LOCUS       DAXISH010000001        83831 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.001, whole genome shotgun sequence.
ACCESSION   DAXISH010000001 DAXISH010000000
VERSION     DAXISH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 83831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83831
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.001"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..454)
                     /locus_tag="ACFOV4_000001"
     CDS             complement(<1..454)
                     /locus_tag="ACFOV4_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFC7618110.1"
                     /translation="MANNKTLFDWVEDRKSTLEEIEQTDFFALPEFVERNLKYPFFEW
                     QKSALENFVIFDRASKLKDFPDIKNRPTHLLFNMATGAGKTMMMAALILYYFEKGYRH
                     FLFFVNQNNIVDKTENNFIDPAHSKFLFTEKILQGDQVIPIHKVETFSP"
     gene            complement(444..2249)
                     /locus_tag="ACFOV4_000002"
     CDS             complement(444..2249)
                     /locus_tag="ACFOV4_000002"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013704.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006306 - obsolete DNA methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HFC7618111.1"
                     /translation="MADKAPKKAKRFILNAVASQPASQPASQLYTKLTRKRQEIFFNQ
                     TLAFDEIDRLFDAKAFSKFSRYTADGKQAVGEIKRHSDGTPAENLIIKGNNLIALHSL
                     AKQFKGKVKLIYIDPPYYFVKKKQQDSFGYNTNFKLSTWLTFMKNRLSIAKELLTDDG
                     IIVISIDDDGNAYLKILLDEIFGFENFIGNLPTIMNLKGNNDEYAFAGTHEYTLVFAK
                     NKDKSTFYEFPIDEDNFLEKWEEDEIGFYKKGAPMRATGTEDKREDRPEMFYPFLVKN
                     NTVSTITDEEFSQIYNKDLEVFNDDFIQKLKEKYENLGYNFILPIADKQWGRWRWGYS
                     IKNKARLQTDIIVSQSKNGISLYKKQRPELDDLPTKKPKTIFYKPEYSSGNGTEQMKN
                     LFGEKAFKNPKPEELIQDFITITTNESDIVLDYHLGSGTTAAVAHKMNRQYIGIEQMD
                     YIETLAVERLKKVIDGEQGGISKAVNWQGGGEFVYAELAPFNETAKQQILACEDSDGI
                     KTLFEGLCERYFLKYNVSVNEFSQIIQEPEFQSLALDEQKQMVLEMLDLNQMYVSLSE
                     MDDEQFAGCLNDDDKALSREFYQSAKNQAEKKDGE"
     gene            complement(2155..2607)
                     /locus_tag="ACFOV4_000003"
     CDS             complement(2155..2607)
                     /locus_tag="ACFOV4_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HFC7618112.1"
                     /translation="MKTVIQTELTQALLSHEKVWANEEKTILAKNILLDLVEKTDPTI
                     IGLLLNNDELKRHFFVEVNGVLVFKLQDLRFFLDKHSVNNSYTKYANRIGLTDGNRFL
                     KDNSDIVLDFPFKDCVLNGGQSTEEGEEIYFKRSSQPASQPASQPIIH"
     gene            complement(2824..3747)
                     /gene="truB"
                     /locus_tag="ACFOV4_000004"
     CDS             complement(2824..3747)
                     /gene="truB"
                     /locus_tag="ACFOV4_000004"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFC7618113.1"
                     /translation="MNTGKPQKRAVNGVLLLDKPEGLSSNTALQKARRLFRAEKAGHT
                     GVLDPLATGLLPVCFGEATKFAQYLLDADKAYTATLKLGEASSTGDAEGEIVATARAD
                     ISLAEFQTACKALTGDIRQVPPMFSALKHEGKPLYEYARKGIVIERKARYITVYAIDI
                     AEFDAPKAVIDVRCSKGTYIRTLSEDIAKHIGTFAHLTALRRTETAGFTIAQSHTLEA
                     LANLNETERDSLLLSCDVLVSHFPQTVLNDYAVHMLRCGQRPRFEEDLPSGTPVRVYT
                     EIGEFVGLAEYQKEICRLKALRLMNTAASAA"
     gene            complement(3780..4151)
                     /gene="rbfA"
                     /locus_tag="ACFOV4_000005"
     CDS             complement(3780..4151)
                     /gene="rbfA"
                     /locus_tag="ACFOV4_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFC7618114.1"
                     /translation="MRKPQRGYARQDRVKEQIMRELAELVRTGLKDPRAGFITVNEVE
                     VTRDYSHATVFYTILNQDAREITEEVLEHARGHLRSELAKRIKLFKIPELHFKYDESL
                     ERGMNLSALIDQVAAEKPVED"
     gene            4341..5585
                     /gene="clpX"
                     /locus_tag="ACFOV4_000006"
     CDS             4341..5585
                     /gene="clpX"
                     /locus_tag="ACFOV4_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFC7618115.1"
                     /translation="MSNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHED
                     GNDGTPSESAGGEPEESGKLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHP
                     KAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQ
                     IITKLLGKCDFDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VASVPPQGGRKHPNQEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSK
                     DENADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEELDEDALINILTEPKNALVK
                     QYQALFGMENVELEFEEGALRSIAWQAMERKTGARGLRSIVERCLLDTMYRLPDLQGL
                     KKVVVGKAVIEEGKEPELVFES"
     gene            complement(5650..6843)
                     /locus_tag="ACFOV4_000007"
     CDS             complement(5650..6843)
                     /locus_tag="ACFOV4_000007"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine/succinyldiaminopimelate
                     transaminase"
                     /protein_id="HFC7618116.1"
                     /translation="MQNYLTPNFAFAPMIPERASGSRVWDTEGREYIDFSGGIAVNAL
                     GHCHPALADALNTQMHKLWHISNIYTTRPAQELAQKLVKNSFADKVFFCNSGAEANEA
                     ALKLARKYARDRFGGGKSEIVACINSFHGRTLFTVSVGGQPKYSKDYAPLPQGITHVP
                     FNDIAALEAAVGEQTCAVIIEPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQT
                     GMGHTGRLFAYEHYGVVPDILSSAKALGCGFPIGAMLATETIAAAFQPGTHGSTFGGN
                     PMACAVGSRAFDIINAPETLHNVCSQGQKLQTALRSLGEQTGVFKQVRGMGLLLGCVL
                     DAPYRGRASEITAAALKHGVMILVAGADVLRFAPSLLLDDEDTAEGLRRLEHVLTEFA
                     AANRP"
     gene            7247..7747
                     /locus_tag="ACFOV4_000008"
     CDS             7247..7747
                     /locus_tag="ACFOV4_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618117.1"
                     /translation="MNAMPQTAAQNETLHICSIIVDDARDFSPMLLDAGRDDTLISES
                     MIPQIRTVAALIAAERHDFSRSSPAEFTDAADFFAARILVLGVRRFHLDVSLLQILKT
                     ANSRARRFAEKHRLFFTPAQAELSLNKHKNRRLLTVETEHEVENKGNPVANSLAFVRK
                     LHTLPL"
     gene            7832..8386
                     /locus_tag="ACFOV4_000009"
     CDS             7832..8386
                     /locus_tag="ACFOV4_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618118.1"
                     /translation="MKKIIASALIATFALAACQDDTQARLEQQQKQIEALQQQLAQQA
                     DDTVYQLTPEAVKDTIPAEAQANGNNGQPVTGKDGQQYIYDQSTGSWLLQSLVGAAAG
                     AFIGNALANKFTRAGNQDSPVARRARAAYHQSAHPNARTSRDLNTRSLRAKQQAAQAQ
                     RYRPTTRPPANYRRPAMRGFGRRR"
     gene            8400..8600
                     /locus_tag="ACFOV4_000010"
     CDS             8400..8600
                     /locus_tag="ACFOV4_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009348581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618119.1"
                     /translation="MPSEGLSDGIFAFVRDIVMLPFDFQTAFCFQAFDVGMAILIYVR
                     WQGGIVMPPLGFQTASYRTVKP"
     gene            complement(8875..10263)
                     /locus_tag="ACFOV4_000011"
     CDS             complement(8875..10263)
                     /locus_tag="ACFOV4_000011"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFC7618120.1"
                     /translation="MSIKFADLNLDKNILSAVSSEGYESPTPIQAQAIPFALEGRDIM
                     ASAQTGSGKTAAFLLPTLQKLTKRSEKPGKGPRALVLTPTRELAAQVEKNALAYAKNM
                     RWFRTVSIVGGASFGYQTRALSKPVDLIVATPGRLMDLMQSGKVDFERLEVLILDEAD
                     RMLDMGFIDDIETIVEATPSDRQTLLFSATWDGAVGKLARKLTKDPEIIEVERVDDQG
                     KIEEQLLYCDDMRHKNRLLDHILRDANIDQCVIFTSTKAMTEVIADELYEKGFAANCL
                     HGDMPQGWRNRTLMDLRKGRCKILVATDVAARGIDVPTITHVINYDLPKQAEDYVHRI
                     GRTGRAGRTGIAITFAEVNEYVKVHKIEKYINRKLPELTIEGMEPTRKRKSAGGKPKG
                     KGGWGNRKSGGRRGDHKPGKEGFGGKTRGEGFKKEGFKKDGFKKTGEGFKGKRKAGDS
                     FAGRGERRYKDR"
     gene            10592..11539
                     /locus_tag="ACFOV4_000012"
     CDS             10592..11539
                     /locus_tag="ACFOV4_000012"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC7618121.1"
                     /translation="MTDITPFANRLGKNIKHLMKWAKRNGIEAWRIYDRDIPQFPFAA
                     DVYGDRIHLQEYDTGWLMRPEEYEAWLAEVLEAVAFVTGFAPEQIRLKRRERQKGLQQ
                     YEKTGKAGDDFVITENGRKFWVNLDKYLDTGLFLDHRNTRKKVGETAAGKRFLNLFSY
                     TGSFTVYAATGGAASSETVDLSNTYLDWARRNFELNGIDTERHKIVRADVFQYLQTAY
                     GEGRRFDLIVMDPPSFSNSKKMSDILDIQRDHKKLIDGAVKLLASDGILYFSNNLRSF
                     VLDDLVSEQYAVKDISKQSVPEDFRNKKIHRCWEIRHKS"
     gene            complement(11592..11924)
                     /gene="trxA"
                     /locus_tag="ACFOV4_000013"
     CDS             complement(11592..11924)
                     /gene="trxA"
                     /locus_tag="ACFOV4_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006662 - glycerol ether metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HFC7618122.1"
                     /translation="MSSELIVHTSDAAFEKDVLNADIPVLLDFWAPWCGPCKMIAPIL
                     DDIAAEFEGRLKVVKINIDDNEATPSRFGVRGIPTLMVFKNGEVVATKVGALAKGQLT
                     AFVEASIA"
     gene            12226..12699
                     /gene="dnrN"
                     /locus_tag="ACFOV4_000014"
     CDS             12226..12699
                     /gene="dnrN"
                     /locus_tag="ACFOV4_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein DnrN"
                     /protein_id="HFC7618123.1"
                     /translation="MTDFSVWETAPFGATVDHILQRYHNVHRAQFEELVPLAQKVAQV
                     HADTFPAEIAELLAYMQNELLMHMMKEERMLFPMINQGVGRGAAMPISVMMHEHEEHD
                     RAIARLKELTDNFQAPEGACGSWTRLYALAKEMVEDLNDHIHLENDILFARVLDS"
     gene            complement(12769..13590)
                     /gene="nadE"
                     /locus_tag="ACFOV4_000015"
     CDS             complement(12769..13590)
                     /gene="nadE"
                     /locus_tag="ACFOV4_000015"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HFC7618124.1"
                     /translation="MMRIFSTGGKMDTQAVITHIVRWLDKYAAQANAKGFVVGVSGGI
                     DSAVVSALAARTGRTTLLLDMPIRQHPDQLERARLHIRNLQGQYANVSAQTVDLTDTF
                     QTFEQTVGVHQTAFDNQPLSLANARSRLRMLTLYYYGQIHGLLVTGTGNKIEDFGVGF
                     FTKYGDGGVDISPIADLTKTQVYRLAEALGVDEAIQKAPPTDGLWDTERTDEEQMGAS
                     YPELEWAMGVYGTRKPEDFEGRQREVLEIYTRLHRAMQHKINPIPVCRIPPELLG"
     gene            13786..15141
                     /gene="xseA"
                     /locus_tag="ACFOV4_000016"
     CDS             13786..15141
                     /gene="xseA"
                     /locus_tag="ACFOV4_000016"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFC7618125.1"
                     /translation="MSDFLHSDVLSVSELNAFAKSLLENHLAGLWIAGEVSNLTRAAS
                     GHYYFSLKDSRAQVRCAMFKGAAARLAKPLKEGDHIEVSGKISIYEARGEFQITVNEV
                     RLKGLGQLYEAYERLKAQLQAEGAFAAERKKLLPTRPQCIGIVTSLAAAALRDVVTTL
                     KRRAPEIPVIVYPTPVQGTGSEFQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNE
                     EPVVRAIEACTVPVVSGVGHETDFTLADFVADMRAPTPTGAAELVSPNRQESLHRLAQ
                     AQGRLKTVLEQRYFDASQKLDWLARQIRHPRQKLDEQRASIGKLAQTLSYSMKQNLRA
                     HTARFERQTQALQHYRPDVSVCKNNIVRLQTALPAAFSQLLTHRRQSLTAQAALLEAV
                     SPQHILERGFSVVKNTRGQVIRNADVLKQGQKLHITFADGETDVRVSKEQGQQDLFDC
                     I"
     gene            16036..17577
                     /locus_tag="ACFOV4_000017"
     CDS             16036..17577
                     /locus_tag="ACFOV4_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HFC7618126.1"
                     /translation="MKFLDREASIAKPGFNRWLVPPAALAVHLAIGQIYAYSVFNAPL
                     TKLIGITESAAGDWKLTTVGWIFSIALAMLGASAALFGTWMERVGPRKAIFAAACCFS
                     LGFFVSAFGVRTHNLFLLYLGNGVIGGVGLGLGYIGPVSTLMKWFPDKPGMATGLAIM
                     GFGGGAMLASPLSVSLMNTFSNAASVGVAETFAVLGLLYLALMMFGAFTIRVPADGWK
                     PEGYTAPKTQNKLVSSNHVNVSQAMKTPQFWLLFWVLCLNVTAGIGVLGQASVMIQEL
                     FSETSIGRQAAVGAGAAAGFVSLLSLFNMGGRFLWSSVSDKIGRKNTYTIFFVLGSLL
                     YFAVPSIGEGGSKALFIIGFCVIISMYGGGFAAIPAYLKDLFGTYQVGAIHGRILLAW
                     STAAVIGPVLVNYIRQSQIDSGIPAAQAYSVTMYIMASLLIIGLLCNLAVKSVHEKYH
                     EKDIKTAARSGNPDDETAISDAYLVGEKVSGGGISVWWRWALAVIPLAYGVVMVFVKA
                     LDLFS"
     gene            complement(17646..18695)
                     /locus_tag="ACFOV4_000018"
     CDS             complement(17646..18695)
                     /locus_tag="ACFOV4_000018"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFC7618127.1"
                     /translation="MSKQPTSKRQWRDGAAPSAKKTAKPFKSKARPKGETRKTAAQAY
                     GQKASDGIKLQNTPKQRADKAKKLVVRNPNQKIMEHARDLKERRSDLSRMEPERLQKV
                     LAASGVGSRREMEEWINNGWVTVNGKTAQLGDKVTPDDHVTVKGSIIKLKWADRLPRI
                     ILYYKQEGEIVSRDDPQGRVSIFDRLPQAASSRWVAIGRLDINTSGLLILTTSGELVQ
                     RFAHPSFEVEREYAVRVLGGLTTEQMRMLTEEGVRLEDGLAKVERIYEQGGEGANKWY
                     NVVIKEGRNREVRRIFESQGLTVSRLVRVGFGPIGLPNRLKRGQFYELNPAEVANIIK
                     WADMLLPGERRRKKA"
     gene            complement(18704..18856)
                     /locus_tag="ACFOV4_000019"
     CDS             complement(18704..18856)
                     /locus_tag="ACFOV4_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020424398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618128.1"
                     /translation="MHKLCPQSRSDDFIRKTAASGTISNRPTEDGILSTRPAAHAAEE
                     PPYQAS"
     gene            18916..19548
                     /gene="pdxH"
                     /locus_tag="ACFOV4_000020"
     CDS             18916..19548
                     /gene="pdxH"
                     /locus_tag="ACFOV4_000020"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HFC7618129.1"
                     /translation="MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAQVNEPT
                     AVNVAAVDGRGRPNSRMVLLKEVNSEGFVFFTNYHSRKGRSLDAHPFVAMTFFWPELE
                     RQVRVEGRVERLAEKLSDEYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKH
                     PLHVPRPPHWGGYIVIPDLLEFWQGRPSRLHDRIQYRLLDGGWIRERLSP"
     gene            complement(19677..20687)
                     /locus_tag="ACFOV4_000021"
     CDS             complement(19677..20687)
                     /locus_tag="ACFOV4_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HFC7618130.1"
                     /translation="MNHTVTLPDQTTFAANDGETVLAAAARQNLNLPHSCKSGVCGQC
                     KAELVSGDIQMDGHSEQALSEAEKAQGKILMCRTTAQSDISINIPGYKADALPVRTLP
                     ARIESIIFKHDVALLKLALPKAPPFAFYAGQYIDLLLPGNVSRSYSIANPPDQEGILE
                     LHIRRRKNGVCSEMIFGSEPKVKEKGIVRVKGPLGSFTLQEDSGKPVILLATGTGYAP
                     IRSILLDLIRQNSSRAVHFYWGARHQDDLYALEEAQGLACRLKNACFTPVLSRPGEGW
                     QGKKGHVQDIAAQDHPDLSEYEVFACGSPAMTEQAKNLFVQQHKLPENLFFSDAFTPS
                     AS"
     gene            complement(20779..22209)
                     /gene="gatB"
                     /locus_tag="ACFOV4_000022"
     CDS             complement(20779..22209)
                     /gene="gatB"
                     /locus_tag="ACFOV4_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003698528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFC7618131.1"
                     /translation="MTWETVIGLEIHVQLNTKSKIFSGASTAFGAEPNAHAGVVECAL
                     PGVLPVMNREVVEKAIKLGLALDAKINRKNVFDRKNYFYPDLPKGYQISQLDLPIVEH
                     GKLEIVVGDDVKTINVTRAHMEEDAGKSVHEGLNGATGIDLNRAGTPLLEVVSEPEMR
                     SAAEAVAYAKALHSLVTWLNICDGNMAEGSFRVDANVSVRPKGQAEFGTRREIKNLNS
                     FRFLEQAINYEAEAQIEILEDGGKVQQATMLFDPEKGETRVMRLKEDAQDYRYFPDPD
                     LLPVIISDAQMQKAKAEMPELPKEMAARFVADYGVSEYDARLLTASRAQAAYFEEAAK
                     ESGQGKPTANWMNGELAAALNKEGMELADSPITAPRLAALVGKIADGTLSSKLAKKAF
                     EAMWAESEATIAEIIEKHGLQQMTDTGAIEAMVDEVLANNAKAVEQFKSGNEKALNAI
                     VGQVMKASKGKANPAQVQELIKAKLA"
     gene            complement(22252..23184)
                     /locus_tag="ACFOV4_000023"
     CDS             complement(22252..23184)
                     /locus_tag="ACFOV4_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK/YbjX family protein"
                     /protein_id="HFC7618132.1"
                     /translation="MKQNRTFTFPDFRTVYSYAPLYRLQHLKYTLRKFFGKKEIYAFE
                     QFVNASPIRQGLFLHCPQNAYPLLREFVDRRFNCKRRLDAMTADFLMAEKLFGTDILH
                     QMEDYRFHLVLAHLSDGISLWLNRNDNCVEEGAWSLSLRDEAGNRLYMATFAFVGTHL
                     LTASVQGPAGEEAKDTVRRITKQLHGLRPQQLMVTALQYFAAVLGLDGAMGIAQKHQV
                     KLRWKLKKRVKMNYDAFWQEYGASLERDGYWHLPQTPARKDLTDIESKKRSMYRKRYE
                     MLDNMVAEMKDGLKTEARGISDGIQTEKPLRRTA"
     gene            complement(23181..24626)
                     /gene="gatA"
                     /locus_tag="ACFOV4_000024"
     CDS             complement(23181..24626)
                     /gene="gatA"
                     /locus_tag="ACFOV4_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFC7618133.1"
                     /translation="MTQYTLKQASVLLQSKQISAVELASAYLAAIAEKNPALNGYITI
                     DQDKTLAEARAADERIAQGNASALTGVPVAYKDIFCQTGWRSACASKMLDNFISPYTA
                     TVVQNLLDEGMVTLGRTNMDEFAMGSTNENSFYGAAKNPWNLEHVPGGSSGGSAAVVA
                     ARLAPAALGSDTGGSIRQPASHCGITGIKPTYGTVSRFGMVAYASSFDQTGPMAQTAE
                     DCAILLNAMAGFDPKDSTSLEREKEDYTRDLNQPLKGLKIGLPKEYFGEGNSADVLTA
                     LQNTIDLLKAQGAELIEVSLPQTKLSIPAYYVLASAEASTNLSRYDGVRYGHRAAQFA
                     DLEEMYGKTRAEGFGSEVKRRIMIGTYVLSHGYYDAYYLKAQKLRRLVADDFQTAFAR
                     CDLILAPTAPTAAPKIGADASPVETYLSDIYTIAVNLAGLPALTLPAGFSGGGLPVGV
                     QLVGNYFAEAKILGAAHQIQLNSDWHGKRPE"
     gene            complement(24689..24979)
                     /gene="gatC"
                     /locus_tag="ACFOV4_000025"
     CDS             complement(24689..24979)
                     /gene="gatC"
                     /locus_tag="ACFOV4_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFC7618134.1"
                     /translation="MALTLADVDKIARLSRLHLTAEEKEKSLQELNDIFTMVEQMQNI
                     NTDGIEPMAHPHEAALRLREDEVTETDRAAEYQAVAPEVRDRLYIVPQVIEE"
     gene            25130..25783
                     /locus_tag="ACFOV4_000026"
     CDS             25130..25783
                     /locus_tag="ACFOV4_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
                     /protein_id="HFC7618135.1"
                     /translation="MGLGMEIGKLIVAFLVLINPFSALSLYLDLTNGHSTKERRKVAR
                     TAAVAVFAVIAVFALIGGTLLKVLGISVGSFQVGGGILVLLIAISMMNGNDNPAKQNL
                     GAQPETGQARPARNAGAIAVVPIAIPITIGPGGISTVIIYASAAKTYGDIALIIAAGL
                     VVSAICYAILIVAGKVSRLLGATGLTILNRIMGMMLAAVSVEIIVSGLKTIFPQLAG"
     gene            25788..27131
                     /locus_tag="ACFOV4_000027"
     CDS             25788..27131
                     /locus_tag="ACFOV4_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HFC7618136.1"
                     /translation="MFHSVNVFTGETLYRRPAQDYAEFERRLADLKMRGGAFAQLGVT
                     ERAARLQKFADRLEAEKERFAEMVCEEVGRCLHECRAEIGKSIELIRYYARLAPELLA
                     HKTIATQASLSQVRFEPLGVVFAVMPWNYPVWQVLRFAVPAMCAGNACAVKPAPSVAR
                     VSQALFDLASDGIPLAGVWLDEAGTLKAVEDTDAMAFTGSTHTGRILAAHAGANLKKT
                     VLELGGSNAFIVMPDADLERAAAEACYSRFRDAGQSCNAAKRIIVTEAAADRFIQLFL
                     AECAKLKMGDPKHPDTTLAPLHREDLRDRVHGQVEDAVSNGAVCLTGGKVPQGSGWFY
                     PATVLDRVNPACRVWREEVFGPVALILRAENEEHAICLANDSPFGLGACIYTADTERA
                     WRFAEKIQAGSVFINRHTSSDLRLPFGGVKDSGYGRELSEFGLYEFVNVKTYWQK"
     gene            complement(27180..27608)
                     /locus_tag="ACFOV4_000028"
     CDS             complement(27180..27608)
                     /locus_tag="ACFOV4_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4124 domain-containing protein"
                     /protein_id="HFC7618137.1"
                     /translation="MNFALSVIAFTLASFLPVPPAGAAVFTWKDGGGNSYSDVPKQLH
                     PDQSQILNPRTLQTKPAVKPKPAVDTNADSAKENEKDIAEKNGQLEEEKKKIAETERQ
                     NKEENCRISKMNLKAVGNSNAKNKDDLIRKYNNDVNKYCR"
     gene            complement(28154..29410)
                     /locus_tag="ACFOV4_000029"
     CDS             complement(28154..29410)
                     /locus_tag="ACFOV4_000029"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HFC7618138.1"
                     /translation="MNAAQLDHTAKVLAEMLTFKQPADAVLSAYFREHKKLGRQDRHE
                     IAETAFAALRHYQKISTALRRPHAQPRKAALAALVLGRSTNISQIKDLFDEEETAFLG
                     NLKARKTEFSDGLNTAAELPQWLVEQLQQHWREEEILAFGRSINQPAPLDIRVNTLKG
                     KRDKVLPLLQAESADAEATPYSPWGIRLKNKIALNKHELFLDGTLEVQDEGSQLLALL
                     LGAKRGEIIVDFCAGAGGKTLAVGAQMANKGRIYAFDIAEKRLANLKPRMTRAGLTNI
                     HPERISSEHDTRIARLAGKADRVLVDAPCSGLGTLRRNPDLKYRQSAETIANLLEQQH
                     SILDAASKLVKPQGRLVYATCSVLPEENELQVERFLSEHPEFELVNCAELLQSLKVDL
                     DTGKYLRLDSARHQTDGFFAAVLQRK"
     gene            complement(29758..30099)
                     /locus_tag="ACFOV4_000030"
     CDS             complement(29758..30099)
                     /locus_tag="ACFOV4_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618139.1"
                     /translation="MKNNVKNWTTKEVKQSLDKFNNILIKNTFLLQYLKKEFSASSAY
                     CLSMLPEEEDIYEILVNGNIIIDLEFNKHTNETVVINVTDVDEYLKTLTNESGRVFFT
                     LAKEIGKQKNI"
     gene            complement(30302..31159)
                     /locus_tag="ACFOV4_000031"
     CDS             complement(30302..31159)
                     /locus_tag="ACFOV4_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1853 family protein"
                     /protein_id="HFC7618140.1"
                     /translation="MNYALDALWWKLTSQPVRDLASLLTAPPLWQSGCELGVRELLGE
                     RGFRYLLALDADPAPLTEHLTRRAPFGHRLGIYAEELLAFWFTNAPHAELLAHNLTVS
                     GSDGNTQGAADFVVRLNGKPYHIELTCKYYGGGTGRLEDMRGLDPKDTLLGKAAKLTA
                     QLGLPHTSDGIRTLRQHGLPLDVKPVSIVRGIGFFPQGFHAFEPPLNPYGWRDVYIQD
                     WAEYGFERQEVRYHLLDRMAYLAPARAAETETLNETEIRRIDQGLIAVLECRPDGFWH
                     EIERIMKAV"
     gene            complement(31220..32035)
                     /locus_tag="ACFOV4_000032"
     CDS             complement(31220..32035)
                     /locus_tag="ACFOV4_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HFC7618141.1"
                     /translation="MTTLKPALPAYLDNIRIILTRTSHPANIGSAARAMKTMGLHKLT
                     IVAPNLMATPMTENPPVFDPEHPQSFKLPEESFILASGAADVLENATIAASLDEALAD
                     TTIACALTSRRREITAPLQTPRDLVSELLQTANRGEKVALVFGNETFGLSIEEVQACN
                     RLMTINGNPDYFSLNLAQAVQVVCYEIFSQTGSPMTHLQQEDHAATHEQIKGMVAHME
                     SVMNDIGFFNRRNGERLMRRMQSLFGRANTQTEDIDILRGFFNTVSHRIHKKD"
     gene            32099..32269
                     /locus_tag="ACFOV4_000033"
     CDS             32099..32269
                     /locus_tag="ACFOV4_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618142.1"
                     /translation="MPSEMFFNNVGNLTLRLKQTRVGRYFTRFGRIYPNQINSDFAAP
                     KDCASEPAVCHP"
     gene            32279..33064
                     /locus_tag="ACFOV4_000034"
     CDS             32279..33064
                     /locus_tag="ACFOV4_000034"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008934 - inositol monophosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006020 - inositol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046855 - obsolete inositol phosphate
                     dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFC7618143.1"
                     /translation="MNPFLNTAFKAARRAGQMMIRAAGNLDAVKTDSKAFNDFVSDVD
                     RNSEIILVEALKEAYPHHKITCEESGSHGKAAAEYEWIIDPLDGTTNFLHGHPQYAIS
                     MALLHKGVLQEALVYAPERNDVYMASRGKGALLNDRRIRVSNRIELNRCLIGTGFPVV
                     DQSMMDKYLAILKDFLAKTAGGRREGAASLDLCAVATGRFDGFFEFNLKPWDIAAGAL
                     IVQEAGGIVTDMTGEDGWLESGDIVAANPKVLAQMLKIISAHV"
     gene            33323..35442
                     /locus_tag="ACFOV4_000035"
                     /pseudo
     CDS             33323..35442
                     /locus_tag="ACFOV4_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219143.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
     gene            35566..37116
                     /locus_tag="ACFOV4_000036"
     CDS             35566..37116
                     /locus_tag="ACFOV4_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HFC7618144.1"
                     /translation="MKKPLISVAAVLLGVALGTPYYLGVKAEESLTQQQKILQETGFL
                     TVESHQYDRGWFTSTETTVIRLKPELLHNAQKYLPDNLKTVLEQPVTLVNHITHGPFA
                     GGFGTQAHIETEFKYAPETEKVLERFFGKQAPVSLANTVYFNGSGKMEVSVPAFDYEE
                     LSGIRLHWEGLTGETVYQKGFKSYRNGYDAPLFKIKLADKGDAAFEKVHFDSETSDGI
                     NPLALGSSNLTLEKFSLEWKEGVDYNVKLNELVNLVTDLQIGAFINPNGSIAPSKIEV
                     GKLAFSTKTGESGAFIDSEGQFRFGTLVYGDEKYGPLDIHIAAEHLDASALTVLKRKF
                     AQISAKKMTEEQIRNDLIAAVKGEASGLFTNNPVLDIKTFRFTLPSGKIDVGGKIMFK
                     DLKKEDLNQLGLMLKKTEADIRMSIPQKMLEDLAVSQAGNIFSVNAEDEAEGRASLDD
                     INETLRLMVDSTVQSMAREKYLTLDGNQIDTAISLKNNQLKLNGKTLQNEPEPDFDEG
                     GMVSEPQQ"
     gene            complement(37477..39264)
                     /gene="lpdA"
                     /locus_tag="ACFOV4_000037"
     CDS             complement(37477..39264)
                     /gene="lpdA"
                     /locus_tag="ACFOV4_000037"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFC7618145.1"
                     /translation="MSLVELKVPDIGGHENVDIIAVEVNVGDTIAVDDTLITLETDKA
                     TMDVPAEVAGVVKEVKVKVGDKISEGGLIVVVEAEGTAAAPKAEAPAAAPAQEAPKAA
                     APAPQAAQFGGSADAEYDVVVLGGGPGGYSAAFAAADEGLKVAIVERYKTLGGVCLNV
                     GCIPSKALLHNAAVIDEVRHLAANGIKYPEPELDIDMLRAYKDGVVSRLTGGLAGMAK
                     SRKVDVIQGDGQFLDPHHLEVSLTAGDAYEQAATTGEKKIVAFKNCIIAAGSRVTKLP
                     FIPEDPRIIDSSGALALKEVPGKLLIIGGGIIGLEMGTVYSTLGSRLDVVEMMDGLMQ
                     GADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDAVLV
                     AAGRAPNGKLISAEKAGVAVTDRGFIEVDKQMRTNVPHIYAIGDIVGQPMLAHKAVHE
                     GHVAAENCAGHKAYFDARVIPGVAYTSPEVAWVGETELSAKASGRKITKANFPWAASG
                     RAIANGCDNGFTKLIFDAETGRIIGGGIVGPNGGDMIGEVCLAIEMGCDAADIGKTIH
                     PHPTLGESIGMAAEVALGTCTDLPPQKKK"
     gene            complement(39341..40924)
                     /gene="aceF"
                     /locus_tag="ACFOV4_000038"
     CDS             complement(39341..40924)
                     /gene="aceF"
                     /locus_tag="ACFOV4_000038"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004742 - dihydrolipoyllysine-residue
                     acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFC7618146.1"
                     /translation="MSIVEIKVPDIGGHENVDIIAVEVKAGDTIAVDDTLITLETDKA
                     TMDVPADAAGVVKEVKVKVGDKISEGGVILTVETGAAAAEAASAAAAPVAAGGATVQV
                     AVPDIGGHTDVDVIAVEIKVGDTVAEDDTLITLETDKATMDVPCTAAGVVKAVFLKVG
                     DKVSEGSAIIEVETVGSAAAAPAQAAQAAAPAAAPPPTAAAAPAAAPAPSAPAAAKID
                     EAAFAKAHAGPSARKLARELGVDLGQVKGTGLKGRIVGDDIKAFVKSVMQGGAAKPAA
                     AGASLGSGLDLLPWPKVDFSKFGNVEVKELSRIKKISGQNLSRNWVVIPHVTVHEEAD
                     MTELEEFRKQLNKEWEREGVKLSPLAFIIKASVSALKAFPEFNASLDGDNLVLKNYFN
                     IGFAADTPNGLVVPVIKDVDQKGLKQISQELTELSKKAREGKLKPQEMQGACFTISSL
                     GGIGGTGFTPIVNAPEVAILGVCKSQIKPVWNGKEFAPRLMCPLSLSFDHRVIDGAAG
                     MRFTVFLAKLLKDFRRITL"
     gene            complement(41074..43737)
                     /gene="aceE"
                     /locus_tag="ACFOV4_000039"
     CDS             complement(41074..43737)
                     /gene="aceE"
                     /locus_tag="ACFOV4_000039"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004738 - pyruvate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HFC7618147.1"
                     /translation="MSTQLHDVDPIETQEWLDALSSVLEYEGGERAQYLLENLVKYCR
                     DKGVRMPHGTTTPYLNTVSVENEKGIPGDQNIEHRIRAFVRWNAAAIVLRAGKKDLEL
                     GGHIASFQSAATMYEVGFNHFWKAKGEGEEGDLVFFQGHVAPGIYARAFVEGRLTEDQ
                     LNNFRQEVDGHGLPSYPHPHLLPDFWQFPTVSMGLGPIMAIYQARFLKYLESRGLAKT
                     KGRKVWCFCGDGEMDEPESQGAIALAAREGLDNLIFVINCNLQRLDGPVRGNGKIIQE
                     LEGNFAGAGWNVVKVIWGRRWDRLLAKDKDGILRQRMEECLDGDYQTYKSKDGAYVRE
                     HFFNTPELKALVADMTDEQLWALNRGGHDPQKVYNAYDRAANHADGKPTVILAKTIKG
                     YGMGASGEGQNVAHQAKKMDKASLKQFRDRFDIPVTDEQIESGDLPYLTFAPDTEEYK
                     YLHARRDALGGYLPQRKPTQEVLEVPELSAFDAQLKSSGEREFSTTMAFVRILSTLLK
                     DKKIGKRVVPIVPDESRTFGMEGMFRQYGIWNPKGQQYTPQDKDQLMFYKESVDGQIL
                     QEGINEPGAMADWIAAATSYANSDFAMIPFYIYYSMFGFQRIGDLAWAAGDMHARGFL
                     LGGTAGRTTLNGEGLQHEDGHSHIQADLIPNCVSYDPTFQYEVAVIVQDGLRRMYANN
                     EDVFYYITLMNENYTHPDMPEGAEQDILKGMYLLKAGGKGDKKVQLMGSGTILQEVVT
                     GAELLKADFGVEADIWSCPSFNLLHRDAVEVERFNRLHPLEAEKVPFVTSKLQGHDGP
                     VIAATDYIRSYADRIRAYIPNDYHVLGTDGFGRSDSRANLRRFFEVDRYNVAVAALSA
                     LAEQGKVSKETVQQAIEKYGIKADSAPSWKR"
     gene            44431..46143
                     /locus_tag="ACFOV4_000040"
     CDS             44431..46143
                     /locus_tag="ACFOV4_000040"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFC7618148.1"
                     /translation="MKASQFFISTLKEAPAEAALASHKLMIRAGLIKANASGLYTWMP
                     MGLRVLRKVENVVREEMARAGSVELLMPVVQPAELWQESGRWEFYGKELLRLKDRHDR
                     DFCMGPTCEEVIADIVRKEINSYKQLPKNFYHIQTKFRDEVRPRFGVMRAREFVMKDA
                     YSFHADYASLQTTYDAMYDSYCRIFTRLGLAFRPVAADTGSIGGTGSHEFQVLAESGE
                     DVIAYSDTSDYAANIELAPTLPLKGERAAAQAVLTKVHTPNVKTIESLVEFLNIPVEQ
                     TLKSIVVEGENEGEIVLLLLRGDHEFNDIKAEKLAGVRSPLTMASPAAIVEQFGANGG
                     SLGPVGFAGKVYADFATEKGADWVIGANEDGYHYTGFNFGRDAAEPEFVDLRNVVEGD
                     ESPDGQGRLKLARGIEVGHVFQLRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVV
                     AAAIEQNNDEKGIIWTKAMAPFEVVIVPMNYKKSDTVREAADKIYAELLAAGADVLLD
                     DRDERAGVLLNDSELLGIPHRIVIGDRALKEGNVEYAERRNNEAQAVAIGEIVARVTA
                     LLNG"
     gene            46206..46862
                     /locus_tag="ACFOV4_000041"
     CDS             46206..46862
                     /locus_tag="ACFOV4_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFC7618149.1"
                     /translation="MASVFLEGEAVEVGNIFCIGRNYAAHIEELKNEIPSEPVVFMKP
                     SGSILNSGGTILLPEFSRDVQFECELVLLVGKDSDGTGEGKDILGCVAGYGVGLDLTA
                     RDIQCRLKEKGLPWLKAKGFRHSACVSDFAAAGRIGNPENVLFSLKQNGVLKQRGDTG
                     LMIYPIREILHKLAADYGLGKGDLVFTGTPSGVGAIGAGDNLALELDGLVRASFTVGC
                     "
     gene            complement(46872..47327)
                     /gene="ruvX"
                     /locus_tag="ACFOV4_000042"
     CDS             complement(46872..47327)
                     /gene="ruvX"
                     /locus_tag="ACFOV4_000042"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFC7618150.1"
                     /translation="MHKIPKGTALAFDFGEARIGVAQGDAELGLSHPLSTVTGGSNDE
                     KFAAIAKLVQEWQPRYFVVGLPVHTDGTKHEMTHLSRKFGRRLNGRFNLPVYWVDERL
                     SSVYAESLLSEAQVFGKKRKSVLDQVAAQAILHGFFEGGPAECFNGREG"
     gene            complement(47320..47868)
                     /locus_tag="ACFOV4_000043"
     CDS             complement(47320..47868)
                     /locus_tag="ACFOV4_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HFC7618151.1"
                     /translation="MNLSNHFLVAMPDMEDAFFSQSVVYICKHDEDGALGIAINKPSP
                     ITMDMIFSATGKNIPMRMQHDSVMMGGPVQVERGYVVHTPIGNWQSSIGVSDNIALTS
                     SRDVIENISREGAVDKALISIGYSSWGKGQLERELADNAWLTVPADEHILFDIPYEHR
                     YAAAFAKLGIDPLALFSGAGHA"
     gene            complement(47870..48430)
                     /locus_tag="ACFOV4_000044"
     CDS             complement(47870..48430)
                     /locus_tag="ACFOV4_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003692938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CreA family protein"
                     /protein_id="HFC7618152.1"
                     /translation="MNRLLLLSAAVLLTACGSGETDKIGRASTVFNILGKNDRIEVEG
                     FDDPDVQGVACYISYAKKGGLKEMVNLEEDASDASVSCVQTASSISFDETAVRKPKEV
                     FKHGASFAFKSRQIVRYYDPKRKTFAYLVYSDKIIQGSPKNSLSAVSCFGGGIPQTDG
                     VQADTSGNLLAGACMISNPIENPDKR"
     gene            48758..50548
                     /locus_tag="ACFOV4_000045"
     CDS             48758..50548
                     /locus_tag="ACFOV4_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HFC7618153.1"
                     /translation="MRYKPLLLALMLVFSTPAVAAHDAAHNRSAEVKKQTKNKKEQPE
                     AAEGKKEKGKNGAVKDKKTGGKEAAKEGKESKKTAKNRKEAEKEATSRQSARKGREGD
                     KKSKAEHKKAHGKSVSGSKEKNAKTQPENKQGKKEAKGQGNPRKGGKAEKDTVSANKK
                     VRSDKNGKAVKQDKKYREEKNAKTDSDELKAAVAAATNDVENKKALLKQSEGMLLHVS
                     NSLKQLQEERIRQERIRQARGNLASVNRKQREAWDKFQKLNTELNRLKTEVAATKAQI
                     SRFVSGNYKNSQPNAVALFLKNAEPGQKNRFLRYTRYVNASNREVVKDLEKQQKALAV
                     QEQKINNELARLKKIQANVQSLLKKQGVTDAAEQTESRRQNAKIAKDARKLLEQKGNE
                     QQLNKLLSNLEKKKAEHRIQDAEAKRKLAEARLAAAEKARKEAAQQKAEARRAEMSNL
                     TAEDRNIQAPSVMGIGSADGFSRMQGRLKKPVDGVPTGLFGQNRSGGDVWKGVFYSTA
                     PATVESIAPGTVSYADELDGYGKVVVVDHGENYISIYAGLSEISVGKGYMVAAGSKIG
                     SSGSLPDGEEGLYLQIRYQGQVLNPSSWIR"
     gene            50675..52159
                     /locus_tag="ACFOV4_000046"
     CDS             50675..52159
                     /locus_tag="ACFOV4_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HFC7618154.1"
                     /translation="MSKPVFKKIALYTLGAISGVAVSLAVQGFAAEKDRRDNEVLPVQ
                     SIRTMAEVYGQIKANYYQDKPDADLFEGAMKGMVAGLDPHSEYMDKKGYAEIKESTSG
                     EFGGLGMEIGQEDGFVKVVSPIEDTPAERAGVKSGDFIVKIDNVSTRGMTVSEAVKKM
                     RGKPGTKITLTLSRKNADKPIVVNLTRAIIKVKSVRHHLIEPDYGYIRVSQFQERTVE
                     SVNTAAKELVKENKGKPLKGLVLDLRDDPGGLLTGAVGVSAAFLPSEAVVVSTKGRDG
                     KDRMVLKAIPEDYVYGMGGDSLAGIPAELKTIPMTVLINSGSASASEIVAGALQDHKR
                     AVIVGTQSFGKGSVQTLIPLSNGSAVKLTTALYYTPNDRSIQAQGIVPDVEVKDKERI
                     FESREADLVGHIGNPLGGEDVNSETLAVPLEKDADKPAVKEKGKKKKDEDLSSRRIPN
                     PAKDDQLRKALDLVKSPEQWQKSLGLAAKKPVSNKDKKDKKDKK"
     gene            52416..54515
                     /gene="uvrB"
                     /locus_tag="ACFOV4_000047"
     CDS             52416..54515
                     /gene="uvrB"
                     /locus_tag="ACFOV4_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFC7618155.1"
                     /translation="MPSERRFRPIPTTHFVRKRITGKIMEVIQYPNSPFKLHQPFPPA
                     GDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQ
                     LYAEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNL
                     MTRDDVIIVATVSAIYGIGDPTEYQQMVLSVKEGDTIAQRDIIATLVSMQYERGDLDF
                     KRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSLIQRVGRYTVFPS
                     SHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCK
                     GIENYSRHFSGKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLV
                     DYGFRLPSARDNRPLKFHEFEKVMPQTVFVSATPAKYEEEHAGQVVEQVVRPTGLVDP
                     QIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRYLHSD
                     IDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQ
                     TIGRAARNVNGVAILYADKITDSMKAAIDETERRREKQIKFNEEHGIVPQQIKKQVKD
                     IIDGVYHEEDGGKGRRQGKNKVKVSEIHNEEDAVKEIAKLEKAMQQAARDLQFEEAAV
                     MRDRIRNIKESLLFGAE"
     gene            54561..55829
                     /locus_tag="ACFOV4_000048"
     CDS             54561..55829
                     /locus_tag="ACFOV4_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT domain-containing protein"
                     /protein_id="HFC7618156.1"
                     /translation="MKLSKTRIDKSGLALAKQQYKDEIDFIELEECFDLYRQSHLSPL
                     SKTTIDIQNILREYIGEYYIAQRLKRKPQIIRKLNRLSVRLTQLQDIGGCRIIVPTNR
                     DVDKIYKFLSSKKDNLDFLIKKVTDYREKGRDDSGYRALHIIIERENLNFELQIRSRI
                     QHYWAESIEKTSVVYGYYLKEQEGDRDVINYFKELSDVFYEIESGRKPTTIQKLNLED
                     LRKRCEVIIQKSDTHKILNSYVNEGIISALIEKEKRNTNSLNNWILIFDWNAGVFVSW
                     DVVAQDPKQAVEVYVNYENQYPSLEGFEVVLIGSSDIASVQKTHSHYFGIASYENILE
                     TLDESIFCFAKKDDIDIGARRILAAMVRHKFWGTKTVTSETLKNHFCQNLFGFDYSLR
                     DLIRKELIKYGRDKDLSLNIAKKMEIESYL"
     gene            56234..56725
                     /locus_tag="ACFOV4_000049"
     CDS             56234..56725
                     /locus_tag="ACFOV4_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC7618157.1"
                     /translation="MKYRRFYRNGGTYFFTVATNKRQRILTDDAVRLALRQAVMAVRE
                     RYPFEILAWVLMPDHLHTIWRLPDNDSAYSERWRQIKRHSKYLIGGNLRLWQKRFWEH
                     TIRDEADFACHFDYLHFNPVKHGYVGQISDWRFSTFHRYVKQGIYPHNWGGGNADFSI
                     EYD"
     gene            56797..56958
                     /locus_tag="ACFOV4_000050"
     CDS             56797..56958
                     /locus_tag="ACFOV4_000050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618158.1"
                     /translation="MRWLNLKNSTSVHNTQGIRTKEAVEQGLRGNNRPEKGIGNRWNY
                     DGFIKELAK"
     gene            57008..57292
                     /locus_tag="ACFOV4_000051"
     CDS             57008..57292
                     /locus_tag="ACFOV4_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618159.1"
                     /translation="MKVITITLFTSCILSGCYGLEYGMSGGIPHDDWAIGSHVSQAKA
                     DAAWKECSDKYMRNGGSGLVEQCMNDKGLIRLSEIRRRQKRAETQRAVIK"
     gene            complement(57417..58133)
                     /gene="trmB"
                     /locus_tag="ACFOV4_000052"
     CDS             complement(57417..58133)
                     /gene="trmB"
                     /locus_tag="ACFOV4_000052"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFC7618160.1"
                     /translation="MTDTAENQTPNDRQAGHPRSIRSFVLRQSHMTAAQQRAIDTLWD
                     SFGIDYQATPADLDANFGSNRPKILEIGFGMGTATAEIARRLPETDFLAIDVHGPGVG
                     NLLKLIEENHLENIRVMRHDAVEVVENMLQDGSLDGIHIFFPDPWHKKRHHKRRLIQA
                     PFIAKLLPKLKTGGYIHLATDWEEYAQQMLEVLSSFDSLQNTAADYAPTPDYRPETKF
                     EARGKRLGHGVWDLVFKRIG"
     gene            complement(58255..59658)
                     /locus_tag="ACFOV4_000053"
     CDS             complement(58255..59658)
                     /locus_tag="ACFOV4_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFC7618161.1"
                     /translation="MNNPDLPYRQALERLSQKQYNFTEVRRLLTEAASAGHPAAAFEL
                     AKHLMDADSPYQDREQGMEMLRIAAEQGHPYARYNLAYIQELEGAPPETLISLYRPLA
                     EEGLPEAQVRLMYLLYASRHFEEALKWAKTSAKNNNPHGQYLLAQYCRYGTPPDFETA
                     HLLYREAAAQGLAAAQWQLGLQYRFGQGTPTDTTQAINHLRAAAQQGYIPAYTPLAEL
                     ILPTAPDKAVYRFQQAAQENDPDAHAALADIYLQGKHPERNYKLALHHAEAAAAERHP
                     EGLRILGDICRYGLGIAPDTEKARHYYRQAAEAGSLTAYQKLISDSALNHPDQYGGIK
                     DSAIRRQRAEQLYQKAQALHYGLQCAPEYAAALKLYTEAAELGHSKAQTNLGSMYYFG
                     QGMTADYNEARKWFEKAAAKKDSMAFYNLACIHYSGHGVGPDKEKACRYLQEAINNGY
                     GQKSVLQELLQQWQNAV"
     gene            complement(59932..61818)
                     /gene="uvrC"
                     /locus_tag="ACFOV4_000054"
     CDS             complement(59932..61818)
                     /gene="uvrC"
                     /locus_tag="ACFOV4_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFC7618162.1"
                     /translation="MPSEAVFQMIDMNTENRSPEQFDIPLFLKNLPKLPGVYRFFDEG
                     GKVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTITRSEAEALILENNFI
                     KALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFGPYPNSNAVRDSIQ
                     VLQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYHDSVREAATFLNGK
                     TDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPNNPNDIDLLA
                     LAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAEAFVAQHYLGKSKPDI
                     IISNFSVPDALKEALEGEHGKQMQFVTKTIGERKVWLKMAEQNAQMAIAQRRLQQSSQ
                     QHRIDELAKILGMDSDGLNRLECFDISHTQGEATIASCVVYDEQNIQPSQYRRYNITT
                     AKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGVAVSVWEELGL
                     HIPLVGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHRFAITGHRK
                     KRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKALAETIY
                     NHLH"
     gene            complement(61873..64035)
                     /locus_tag="ACFOV4_000055"
     CDS             complement(61873..64035)
                     /locus_tag="ACFOV4_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFC7618163.1"
                     /translation="MQQKIRFQIEGMTCQACASRIEKVLNKKDFVESAGVNFASEEAQ
                     VVFDDSKTSVADIAKIIEKTGYGAKEKTEDTLPQPEAEHHIGWRLWLLFTINVPFLIG
                     MAGMMIGRHDWMIPPLWQFALASVVQLWLAIPFYKSAWASIKGGLANMDVLVTIGTVS
                     IYLYSVYMLFFSPHAAYGMAHVYFEVGVMVIGFVSLGKFLEHRTKKSSLNSLGLLLKL
                     TPTQVNVQRNGEWKQLPIDQVQIGDLIRANHGERIAADGIIESGSGWADESHLTGESN
                     PEEKKAGGKVLAGALMTEGSVVYRATQLGSQTQLGDMMNALSEAQGSKAPIARVADKA
                     AAVFVPAVVGIALLTFIVTWLIKGDWTVALMHTVAVLVIACPCALGLATPAAIMVGMG
                     KAVKHGIWFKDAAAMEEAAHVDAVVLDKTGTLTEGSPQVAAVYCVPDSGFDEDALYRI
                     AAAVEQNAAHPLARAIVSAAQARGLDIPAAQNAQTVVGAGITAEVEGVGLVKAGKAEF
                     AELALPKFLDGVWDIASIVAVSVDNKPIGTFALADALKADTAEAIGRLKKHNIDVYIM
                     SGDNQGTVEYVAKQLGIAHAFGNMSPRDKAAEVQKLKAAGKTVAMVGDGINDAPALAA
                     ANVSFAMKGGADVAEHTASATLMQHSVNQLADALSVSRATLRNIKQNLFFAFFYNILG
                     IPLAALGFLNPVIAGAAMAASSVSVLSNALRLKRVKID"
     gene            64174..65124
                     /gene="trxB"
                     /locus_tag="ACFOV4_000056"
     CDS             64174..65124
                     /gene="trxB"
                     /locus_tag="ACFOV4_000056"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFC7618164.1"
                     /translation="MSQHRKLIILGSGPAGYTAAVYAARANLNPVIITGIAQGGQLMT
                     TTEVDNWPADADGVQGPELMARFLAHAERFGTEIIFDQINAVDLQKRPFTLKGDMGEY
                     TCDALIVATGASAKYLGLPSEEAFAGKGVSACATCDGFFYKNQDVAVVGGGNTAVEEA
                     LYLANIAKTVTLIHRRSEFRAEKIMIDKLMKRVEEGKIILKLESNLQEVLGDDRGVNG
                     ALLKNNDGSEQQIAVSGIFIAIGHKPNTDIFKGQLEMDEAGYLKTKGGTADNVGATNI
                     EGVWAAGDVKDHTYRQAITSAASGCQAALDAERWLGSQNI"
     gene            65280..65648
                     /gene="rpsF"
                     /locus_tag="ACFOV4_000057"
     CDS             65280..65648
                     /gene="rpsF"
                     /locus_tag="ACFOV4_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFC7618165.1"
                     /translation="MRHYEIVLIVHPDQSEQVPAMVERYKTMIAEANGKIHRLEDWGR
                     RQLAYPINKIHKAHYVLMNIETTPEVVEELETAFRFNDAVLRHLTIKTKHAVTEASPM
                     LGGEKAKNLLSGASEEAVAQ"
     gene            65649..65951
                     /gene="priB"
                     /locus_tag="ACFOV4_000058"
     CDS             65649..65951
                     /gene="priB"
                     /locus_tag="ACFOV4_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003678153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030894 - replisome [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HFC7618166.1"
                     /translation="MGFNNLVSLAALIEKVFPIRYTPAGIPVLDIILKHKSWQEENGQ
                     QCLVQLEIPARILGRQAEEWQYRQGVYVHVEGFLAQKSRRSLMPMLRIQNIQEYKG"
     gene            65958..66188
                     /gene="rpsR"
                     /locus_tag="ACFOV4_000059"
     CDS             65958..66188
                     /gene="rpsR"
                     /locus_tag="ACFOV4_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009120066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFC7618167.1"
                     /translation="MARQSFKRRKFCRFTAEKIQEVDYKQVDLLKDFISENGKIIPAR
                     ITGTKAFYQRQLAVAVKRARFLALLPYTDQHK"
     gene            66205..66657
                     /gene="rplI"
                     /locus_tag="ACFOV4_000060"
     CDS             66205..66657
                     /gene="rplI"
                     /locus_tag="ACFOV4_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFC7618168.1"
                     /translation="MQIILLEKIGGLGNLGDIVTVKNGYARNFLIPAGKAKRATEANM
                     KEFEARRAELEAKQAEILADARVRQEKLDGQTVTVAQKAGVDGRLFGSVTNADIAAAI
                     VAAGIEAVKANVRLPNGPLKAVGEYEVEVALHTDAVAKITVAVVAATE"
     gene            66671..66778
                     /locus_tag="ACFOV4_000061"
     CDS             66671..66778
                     /locus_tag="ACFOV4_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HFC7618169.1"
                     /translation="MPSETLPIVGMWFQTVFVLFSVYSAKIGMVVFIVD"
     gene            67353..67508
                     /locus_tag="ACFOV4_000062"
     CDS             67353..67508
                     /locus_tag="ACFOV4_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618170.1"
                     /translation="MYTGHYGGNTVWEAAASRGIGTAGDAPMPSGVKAGQSAVWKKAM
                     ESVGRRS"
     gene            complement(67624..68430)
                     /locus_tag="ACFOV4_000063"
     CDS             complement(67624..68430)
                     /locus_tag="ACFOV4_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFC7618171.1"
                     /translation="MWHWDIILILLAVGSAAGFIAGLFGVGGGTLIVPVVLWVLDLQG
                     LAQHPYAQHLAVGTSFAVMVFTAFSSMLGQHKKQAVDWKTVFAMMPGMIFGVFTGALS
                     AKYIPAFGLQIFFILFLTAVAFKTLHTDPQTASRPLPGLPGLTAVSTLFGTMSSWVGI
                     GGGSLSVPFLIHCGFPAHKAIGTSSGLAWPIALSGAISYLLNGLNIAGLPEGSLGFLY
                     LPAVAVLSAATIAFAPLGVKTAHKLSSAKLKKSFGIMLLLIAGKMLYNLL"
     gene            complement(68431..69177)
                     /gene="pssA"
                     /locus_tag="ACFOV4_000064"
     CDS             complement(68431..69177)
                     /gene="pssA"
                     /locus_tag="ACFOV4_000064"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003882 - CDP-diacylglycerol-serine
                     O-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HFC7618172.1"
                     /translation="METPTNTPQRSLRQNSIYLLPNSFTIAALFSAFYAITQSMHGRY
                     ETAAIAVFISMLLDGMDGRVARLTNSQSAFGEQLDSLADMVSFGVAPALIAYKWQLWQ
                     FGKIGYSVAFIYCACAALRLALFNTLIGKVDKRWFIGVPSPTAAALIVGLIWVNHSVE
                     KFPAVHWWALGITLFAGLSMIVQIPFWSFKEINIRRQVPFVGMLLAVLLLLLVTWEPS
                     LVLFLFFLGYSLSGYIMAARRFWKKYRKAD"
     gene            complement(69251..69376)
                     /locus_tag="ACFOV4_000065"
     CDS             complement(69251..69376)
                     /locus_tag="ACFOV4_000065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618173.1"
                     /translation="MPSNNIHPAKIRNNTPGGRQSQTAPQSIRHQKNKPPPRASS"
     gene            69760..70242
                     /locus_tag="ACFOV4_000066"
     CDS             69760..70242
                     /locus_tag="ACFOV4_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4189 domain-containing protein"
                     /protein_id="HFC7618174.1"
                     /translation="MMKKILAVSALCLMTAAARAADTYGYLAVWQNPQNADDVLQVKT
                     TKEDSTKSEAFAELEAFCKGQDTLAGIAEDEPTGCRSVVSLNNTCVALAYPKALGVMR
                     VENAVVITSPRFTSVHQVALNQCIKKYGAQGQCGLETVYCTSSSYYGGTVRSLIQNLK
                     "
     gene            complement(70294..71505)
                     /locus_tag="ACFOV4_000067"
     CDS             complement(70294..71505)
                     /locus_tag="ACFOV4_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HFC7618175.1"
                     /translation="MNQLKLAVSGAQILFVAFGAMVLVPLLTGLNPALALLGAGLGTL
                     LFQITTKRKVPIFLGSSFAFIAPIIYSVGEWGLPSTMFGLFAAGFMYFVFAALIRWRG
                     LAAVHKLLPPVVIGPVIMVIGLSVAVAASSMAMGQADGKQVIDYTDSLILSGFTFAVT
                     AIVSVFGSRMMKLIPILIGVASGYVLALLMGLVDTASIAHAPWFAVPHFETPQVNWQA
                     ALFMLPVAVAPAIEHIGGIMAIGNVTGKDYTKDPGLDKTLAGDGLGVCVAGLIGGPPV
                     TTYGEVTGAVMITKNSNPVIMTWAAVFAVCMAFFGKFNAFLASIPMPVMGGIMLLLFG
                     TIASLGVKTLIDAKVDLMLPKNLVIVSSVLTTGIGGMTLKLGSFSFAGVGLCAVLAIM
                     LNSLLPDPKES"
     gene            71728..74166
                     /locus_tag="ACFOV4_000068"
     CDS             71728..74166
                     /locus_tag="ACFOV4_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFC7618176.1"
                     /translation="MTEKSHKKTAKGRAGSPSPTSARNKKADNGARGNKVSERLKAVK
                     ELQKTETKKARPEHVVNLIGDALWLMGLAATLYLAISLISFDMGDPSWSHSSPVVEDV
                     ANWGGLFGAYVADVGYYLFGWSFWWWIAAACVMLYKNFRLHAKQTENEAYNHKIAAAA
                     LFVLTVFSPVLEYFVLGGKYADSLPVGAGGMVGIRVGAVFAWLLGKSGSLLIILVVLL
                     LSLSLLVQISWLEFLNGAGRAVQNRLSALSGKVMALGKRRPNSKTDGVDTQNTRRMVK
                     EAKNITAKPVALPEGSSSNRKSVAVSVAPSPKIQVSLFEDDEPRQAGEYHKPTLNLLR
                     IPDSEPVSINPAELERTAELIESKLAEFGIGVQVVSATSGPVITRYEIEPAQGVKGSQ
                     IVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDKRQDVMLSEILSSPVFAEAKSK
                     LTVALGKDIAGTPVVGDLAKMPHLLVAGMTGSGKSVGVNGMIMSMLFKATPDEVRFIM
                     IDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEKRYRLLSHAGVRNLEGFN
                     QKVEAAKAAGKPLLNPFSLNPDSPEPLEKLPMIVVVIDELADLMMTERKAVEQQIARL
                     AQKARAAGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDSRTILDQMGADELL
                     KYGDSLFLQPGSAEPTRLQGAFVSDDEVHQVVNYVKSQAPADYIEGLLSGEAALETAN
                     IVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALENAGVVSPTD
                     LNGSRKILAHKDHL"
     gene            74375..75685
                     /gene="tig"
                     /locus_tag="ACFOV4_000069"
     CDS             74375..75685
                     /gene="tig"
                     /locus_tag="ACFOV4_000069"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003742150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFC7618177.1"
                     /translation="MSVTVETLENLERKVVLSLPWSEINAETDKKLKQTQRRAKIDGF
                     RPGKAPLKMIAQMYGASAQNDVINELVQRRFHDVAVAQELKVAGFPRFEGVEEQDDKE
                     SFKVAAIFEVFPEVVIGDLSAQEVEKVTASVGDAEVDQTVEILRKQRTRFNHVEREAR
                     NGDRVIIDFEGKIDGEPFAGGASKNYAFVLGAGQMLPEFEAGVVGMKAGESKDVTVNF
                     PEEYHGKDVAGKTAVFTITLNNVSEATLPEVDADFAKALGIADGDVAKMREEVQKNVS
                     REVERRVNEQTKESVMNALLKAVELKAPVALVNEEAARLANEMKQNFVNQGMADAANL
                     DLPLDIFKEQAERRVSLGLILAKLVDENKLEPTEEQVKAVVANFAESYEDPQEVIDWY
                     YAEPSRLQAPTSLAIESNVVDFVLGKAKVNEKALSFDEVMGAQA"
     gene            75781..76395
                     /gene="clpP"
                     /locus_tag="ACFOV4_000070"
     CDS             75781..76395
                     /gene="clpP"
                     /locus_tag="ACFOV4_000070"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFC7618178.1"
                     /translation="MSFDNYLVPTVIEQSGRGERAFDIYSRLLKERIVFLVGPVTDES
                     ANLVVAQLLFLESENPDKDIFFYINSPGGSVTAGMSIYDTMNFIKPDVSTLCLGQAAS
                     MGAFLLSAGEKGKRFALPNSRIMIHQPLISGGLGGQASDIEIHARELLKIKEKLNRLM
                     AKHCGRDLADLERDTDRDNFMSAEEAKEYGLIDQILENRASLQF"
     gene            complement(76452..77717)
                     /gene="ispG"
                     /locus_tag="ACFOV4_000071"
                     /gene_synonym="gcpE"
     CDS             complement(76452..77717)
                     /gene="ispG"
                     /locus_tag="ACFOV4_000071"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HFC7618179.1"
                     /translation="MNTLQRRKTHQVRIDHITVGSEAPVVIQSMTNTDTADAKATALQ
                     IKELSDAGSEMVRITVNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPE
                     CGKALSKYRINPGNVGKGVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMD
                     ANLASSAPKPPEEVTKEALIVSALESAEKAVLLGLPEDKIILSCKVSAVQDLIQVYRE
                     LGSRCAYPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEV
                     VVGQEILQTMGLRSFTPMVTACPGCGRTTSTVFQELAQDVQNYLRQKMSVWRTAYPGV
                     ESLNVAVMGCVVNGPGESKLADIGISLPGTGETPVAPVYVDGERKVTLKGDNIATEFL
                     AIVEEYVKTNYGENGSKRNQNKIIPIQSL"
     gene            complement(77733..78494)
                     /gene="pilW"
                     /locus_tag="ACFOV4_000072"
     CDS             complement(77733..78494)
                     /gene="pilW"
                     /locus_tag="ACFOV4_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis/stability protein PilW"
                     /protein_id="HFC7618180.1"
                     /translation="MPFKPSKRISLLLVLALGACSTSYRPSRAEKANQVSNIKTQLAM
                     EYMRGQDYRQATASIEDALKSDPKNELAWLVRAEIYQYLKVNDKAQKSFRQALSIKPD
                     SAEINNNYGWFLCGRLNRPAESMAYFDKALADPTYPTPYIANLNKGICSAKQGQFGLA
                     EAYLKRSLAAQPQFPPAFKELARTKMLAGQLGDADYYFKKYQSRVEVLQADDLLLGWK
                     IAKALGNAQAAYEYEAQLQANFPYSEELQTVLTGQ"
     gene            complement(78497..79591)
                     /gene="rlmN"
                     /locus_tag="ACFOV4_000073"
     CDS             complement(78497..79591)
                     /gene="rlmN"
                     /locus_tag="ACFOV4_000073"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFC7618181.1"
                     /translation="MKTNLLNYDLQGLTRHFADMGEKPFRAKQVMRWMHQSGAQNFDE
                     MTDLAKSLRHKLNEQAGIEIPKLMMSQKSSDGTRKWLLDVGTGNGVETVFIPESDRGT
                     LCISSQVGCALECTFCSTGRQGFNRNLTAAEIIGQLWWANKAMGVTPKNERVISNVVM
                     MGMGEPMANFDNVVTALSIMLDDHGYGLSRRRVTVSTSGMVPQMDRLRDVMPVALAVS
                     LHASNDEVRNQIVPLNKKYPLKELMAACQRYLVKAPRDFITFEYVMLDGINDKAQHAR
                     ELIELVTDVPCKFNLIPFNPFPNSGYERSSNENIRVFRDILQQAGFVVTVRKTRGDDI
                     DAACGQLAGQVQDKTRRQQKWQQILIGQQG"
     gene            complement(79735..80160)
                     /gene="ndk"
                     /locus_tag="ACFOV4_000074"
     CDS             complement(79735..80160)
                     /gene="ndk"
                     /locus_tag="ACFOV4_000074"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFC7618182.1"
                     /translation="MAIERTISIIKPDAVGKNVIGKIYSRFEENGLKIVAAKMKQLTL
                     KEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPAEAAEGT
                     IRADFATSVSINAVHGSDTPENAALEIAYFFSQTEICPR"
     gene            complement(80219..81370)
                     /gene="zapE"
                     /locus_tag="ACFOV4_000075"
     CDS             complement(80219..81370)
                     /gene="zapE"
                     /locus_tag="ACFOV4_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HFC7618183.1"
                     /translation="MSNRDQLFKAPPFENHSPLTWYQAASQLPNFIRDDAQAAAIEHL
                     DRLWTELMMFKRKRNRFLGRSLRSPQVPKGLYFYGGVGRGKSFLMDAFFGCLPYRRKR
                     RVHFHAFMAEIHQRLKTLKSESNPLKSVAAEIAKETRVLCFDEFHVSDIADAMILGRL
                     LENLLNEGVVLVATSNYAPSELYPQGQNRSSFLPTIALIESSLTVLNVDGGEDYRLRT
                     LRPAEIFFTPANEENEAKLAKLFKEMTGITDLNPGISTIHGREIPHKAESGRAIWFDF
                     RALCFGPRSQSDYLYLAEHYEMVFISGLEQLSPQEKAEARRLTWLIDVLYDFRVKLCA
                     TGAVDVNHIYTEGDFAEEFTRTASRMVEMQSEVYLEQPHLTLSPKDSGG"
     gene            complement(81761..82588)
                     /gene="fghA"
                     /locus_tag="ACFOV4_000076"
     CDS             complement(81761..82588)
                     /gene="fghA"
                     /locus_tag="ACFOV4_000076"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011961786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018738 - S-formylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0046294 - formaldehyde catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HFC7618184.1"
                     /translation="MKLIEQHQIFGGLQQVWAHDAQTLQCEMKFAVYLPNNSENQPLG
                     VIYWLSGLTCTEQNFITKSGFQLYAAEHQVIVVAPDTSPRGEQVPNDAAYDLGQGAGF
                     YLNATEQPWATNYQMYDYILNELPDLVEANFSTNGKRSIMGHSMGGHGALVLALRNRK
                     RYQSVSAFSPILSPSLVPWGEKAFTAYLGEDREKWQQYDASSLIQQGYKVQGIRIDQG
                     LEDEFLPTQLRTEDFIETCRAANQPVDVRFHKGYDHSYYFIASFIGEHIAYHAAFLK"
     gene            complement(82597..83706)
                     /locus_tag="ACFOV4_000077"
     CDS             complement(82597..83706)
                     /locus_tag="ACFOV4_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004024 - alcohol dehydrogenase (NAD+)
                     activity, zinc-dependent [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0051903 - S-(hydroxymethyl)glutathione
                     dehydrogenase [NAD(P)+] activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase"
                     /protein_id="HFC7618185.1"
                     /translation="MKSRAAVAFAPNQPLQIVEIDVEMPRKGEVLIRNTHTGVCHTDA
                     FTLSGSDPEGVFPVVLGHEGAGVVVAVGEGVSSVKPGDHVIPLYTAECGECEFCCSGK
                     TNLCVSVRDTQGKGLMPDGTTRFSYQGQPIYHYMGCSTFSEYSVVAEVSLAKINPEAN
                     HEQVCLLGCGVTTGIGAVHNTAKVQEGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPSKFELAKQFGATDCLNPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRQALES
                     AHRGWGQSIIIGVAGAGQEISTRPFQLVTGRVWKGSAFGGVKGRSELPKMVEDSMKGD
                     IELEPFVTHTMTLDQINKAFDLMHEGKSIRAVIHY"
BASE COUNT        19962 a        20502 c        22571 g        20796 t
ORIGIN      
        1 gtgggctaaa cgtttctact ttgtgaatgg gaataacttg gtcgccttgc aaaatcttct
       61 cggtaaataa aaattttgag tgcgccgggt caataaaatt attttccgtt ttatccacga
      121 tattattttg attgacgaaa aacaaaaaat gccgataacc tttttcaaaa taatacaaaa
      181 tcaacgccgc catcatcatc gttttgccag cacctgttgc catattgaac agcaaatggg
      241 tagggcggtt tttgatgtca gggaaatcct ttaattttga agcgcggtca aaaatcacaa
      301 agttttctaa agccgatttt tgccattcaa aaaacggata ttttaaattg cgttctacaa
      361 attcaggcag cgcgaaaaaa tctgtctgtt ctatttcttc cagcgttgat ttgcggtctt
      421 ccacccaatc aaataacgtt ttattattcg ccatcttttt tctccgcttg attttttgct
      481 gattgataga attcacggct taacgcttta tcgtcatcat ttaagcaacc tgcaaattgc
      541 tcatcatcca tttcggataa tgaaacatac atttgattta aatccaacat ttcaagcacc
      601 atttgttttt gttcgtctaa tgccaaggat tgaaattcag gctcttgaat gatttgacta
      661 aattcattta cgctgacgtt gtatttcaag aaatagcgtt cgcataaacc ttcaaacagc
      721 gttttgatgc cgtctgaatc ttcgcaagcc aaaatttgtt gttttgcggt ttcgttaaat
      781 ggagcaagtt cggcatagac aaactcgccg ccaccttgcc aattcacggc tttggaaata
      841 ccgccttgct cgccatcaat cacttttttc aagcgttcaa cggcaagcgt ttcaatataa
      901 tccatttgtt caataccgat atattgtcgg ttcattttgt gggcaacggc ggcggttgtg
      961 ccactaccaa gatggtagtc taagacgatg tcggattcgt tggttgtgat ggtaataaaa
     1021 tcttggataa gttcttctgg tttaggattt ttaaatgcct tttcaccaaa aagatttttc
     1081 atctgttcag ttccattacc actactgtat tcaggtttat aaaaaatagt tttaggtttt
     1141 tttgtaggta aatcatctaa ttcaggtctt tgttttttat acaaggaaat tccattttta
     1201 gattggctaa caataatatc cgtctgcagc cttgccttat tctttattga atacccccaa
     1261 cgccaacgcc cccattgttt atcagcaata ggtaaaataa aattgtatcc aagattttcg
     1321 tatttctctt ttagtttttg aataaaatca tcattgaata cttctaaatc tttattatag
     1381 atttgagaaa attcttcatc tgtaattgta ctaactgtgt tattttttac caaaaaagga
     1441 tagaacattt caggtctatc ttctctttta tcttcggttc ctgttgctcg cattggagct
     1501 ccttttttat aaaacccaat ttcatcttct tcccatttct ctaaaaaatt atcttcatct
     1561 attggaaatt cataaaaagt agatttatct ttatttttag caaagactag tgtgtattcg
     1621 tgagtgcctg caaaagcata ttcatcatta ttacctttta aattcataat agtgggtaaa
     1681 tttccgataa aattttcaaa tccaaaaatt tcatctaaca aaatctttaa ataagcattt
     1741 ccgtcatcat caatggaaat aacaataatc ccatcatcag ttaataattc tttggcaatt
     1801 gataaacgat ttttcataaa tgtaagccaa gtagataatt taaagttagt gttataacca
     1861 aaactatctt gttgtttctt tttaacaaaa taataaggcg gatcaatata aatcaacttc
     1921 actttgcctt taaactgttt ggcaagcgaa tgtagggcta tcagattatt gcctttgata
     1981 atgagatttt cggcgggtgt gccgtctgaa tgacgtttga tttcgccaac cgcttgtttg
     2041 ccgtctgcgg tatagcgaga gaattttgag aatgcttttg cgtcaaaaag ccgatcgatt
     2101 tcatcaaaag caagcgtttg attaaaaaag atttcttgtc tttttcgggt taatttagtg
     2161 tataattggc tggctggctg gctggctggc tggctggcta ctgcgtttaa aataaatctc
     2221 ttcgccttct tcggtgcttt gtccgccatt caatacgcaa tctttaaacg gaaaatccaa
     2281 cacaatatcc gaattgtctt tcaaaaagcg gttgccgtcc gtcaaaccaa tgcggttggc
     2341 gtattttgtg taggaattat tgacgctgtg tttgtccaag aaaaaacgta aatcctgcaa
     2401 tttaaacacc aaaacaccat tcacttccac aaagaaatgg cgttttaact catcattatt
     2461 caataacaaa ccgataatgg tcgggtcggt tttttccacc aaatccaaca gaatgttttt
     2521 ggctaaaatg gttttttctt cgttcgccca tactttttcg tgtgatagca gggcttgggt
     2581 taattcggtt tgaatgactg tcttcatcgt tataaatcct catcagtcat tttaatgtgc
     2641 cattcttgtg taacggcaaa tggctttgca aataaattct aataaaatca atcctttgat
     2701 gtcttttctg tttcgggggg cgttcgcaaa gttgcgataa gcggggaggg tgtccgagtg
     2761 tgtcgggatt ttgcggaaat atcaacacat tattcaaaca cagcccgtat ttttaaccgt
     2821 cgttcaggcg gcggatgccg ccgtgttcat caggcgcaag gctttcagac ggcatatttc
     2881 cttttgatat tctgccaaac cgacaaattc tccaatttca gtgtaaacgc gtaccggcgt
     2941 gccggaaggt aggtcttcct cgaaacgcgg acgttgtccg cagcggagca tatggacggc
     3001 ataatcgttt aaaacggttt ggggaaagtg tgaaaccaat acgtcgcagg atagcagcaa
     3061 gctgtcgcgt tctgtttcgt tcaaatttgc caaggcctca agcgtgtggc tttgggcgat
     3121 ggtaaagccg gcggtttcgg tgcggcgcaa ggcggtcagg tgggcgaacg tgccgatgtg
     3181 tttggcgatg tcttcgctga gggtgcggat gtaggtgcct ttgctgcaac gtacgtcgat
     3241 gacggctttg ggcgcgtcaa attcggcaat atcgatggcg taaacggtaa tgtagcgcgc
     3301 tttgcgttcg atgacgatgc ctttgcgggc gtattcgtac agcggtttgc cttcgtgctt
     3361 gagcgcggaa aacattggcg gcacttggcg gatgtcgccc gttaatgctt tgcaggccgt
     3421 ctgaaattcg gctaaggaaa tatcggcacg ggcggtggca acgatttcgc cttcggcatc
     3481 acccgtgctg ctggcttcgc cgagtttcag cgtggcggtg taggctttgt cggcatccag
     3541 caggtattgg gcgaacttgg tcgcttcgcc gaagcagacg ggcaaaagtc cggttgccaa
     3601 aggatcgagc acgccggtat gtccggcttt ttcggcacgg aacaaacgcc gcgctttttg
     3661 cagcgcggtg ttgctggaaa ggccttcggg tttgtccaag agcaaaacac cgttgacggc
     3721 acgtttttgg ggtttgcctg tattcatggt tcgatgttcg gacggcatgg gcatatccgt
     3781 cagtcttcaa ccggtttttc cgccgctact tggtcgataa gggcggacag gttcataccg
     3841 cgttccaagg attcgtcgta tttgaaatgc agctcgggga ttttgaacag cttgatgcgt
     3901 ttggccaatt cgctgcggag gtgtccgcgc gcgtgttcca gcacttcttc cgtaatttcg
     3961 cgcgcgtctt ggtttaaaat ggtgtagaac acggtggcgt ggctgtaatc gcgggtaact
     4021 tcgacttcgt tgacggtaat gaagccggcg cgcgggtctt tcagtccggt acggacgagt
     4081 tcggcaagct cgcgcataat ttgttctttg acacggtctt ggcgggcata gccgcgttgg
     4141 ggttttctca tgaatatcct cagatttcag atttggtttc agacggcatt tttgccgccg
     4201 gggcggttgc gaaagggcgt attatagccg aatcggcggg attttaaggt aatacattga
     4261 taagaacgga tatagttatt atacttggca acccgaacgg cgcgtgccgt ttctgtaacg
     4321 catacattgt aaagaaagcc atgtccaacg aaaaccgtac ctgttccttt tgcggaaaat
     4381 ccaaatcaca cgtcaaacat ttaattgagg gcgaaaacgc ctttatctgt gacgaatgcg
     4441 tctcaaactg tattgaaata ttgcatgaag acggaaatga cggcacgcct tcggaaagtg
     4501 ccggagggga gccggaagaa tccggcaagc tccccacgcc cgccgaaatc gtcgccaacc
     4561 tcaacgacca cgttatcggt caggaacaag ccaagaaagc cttggcggtg tcggtgtaca
     4621 accattacaa acgcctgcgc cacccgaaag ccggagctaa tgtcgaattg tcgaaatcca
     4681 acatcctgct tatcggcccg accggatcgg gtaaaaccct gctggcgcaa tctttggcgc
     4741 gcaaactgga tgtgccgttc gtgatggcag atgcaaccac gctgaccgaa gcaggttatg
     4801 tcggcgaaga tgtcgagcaa atcatcacca aactcttggg caaatgtgat ttcgatgtcg
     4861 aaaaagccca acgcggcatc gtctatatcg acgaaatcga taagatttca cgcaaaagcg
     4921 acaatccgtc catcacgcgt gacgtgtccg gcgaaggcgt gcaacaagcc ttgctgaaac
     4981 tgattgaagg tacggtggcc agcgttccgc cccaaggcgg ccgcaagcat ccgaatcagg
     5041 aatttatcaa cgtcgatacc accaacatcc tgtttatctg cggcggcgcg tttgcaggct
     5101 tggaaaaagt catccgccag cgtactgaaa aaggcggtat cggtttcggt gcgtccgttc
     5161 acagcaagga cgaaaatgcc gacattacca agctgttcgg catcgtcgaa ccggaagatt
     5221 taatcaaatt cggtctgatt ccggaattaa tcggacgttt gcctgtgatt gcaacgttag
     5281 aagaactgga tgaggacgcg ctgattaata ttttgaccga gccgaaaaac gctttggtca
     5341 agcagtatca agccttgttc ggtatggaaa atgtcgagtt ggaatttgaa gaaggcgcat
     5401 tgcgttccat tgcgtggcag gcaatggagc gcaaaaccgg cgcgcgcggc ctgcgttcca
     5461 tcgtcgaacg ctgcctgctc gatacgatgt accgcctgcc tgatttgcaa ggcttgaaaa
     5521 aagtggtggt cggtaaggca gtcatcgaag agggcaagga accggaattg gtgttcgagt
     5581 cctgatggca aacaaaaccg cttcggaacg ttgaaccacg tttccgaagc ggttttttgt
     5641 ttttgatgcc taggggcggt ttgcggcggc aaattccgtc agcacgtgtt ccaaacgccg
     5701 caaaccttcc gccgtatcct catcgtccaa cagcagcgaa ggcgcgaaac gcaatacgtc
     5761 cgcacccgca accaaaatca tcacgccgtg tttcaaggcg gcggcggtta tttcggatgc
     5821 gcgtccgcga taaggcgcgt ccaacacgca gccgagcagc agccccatgc cgcgaacttg
     5881 cttaaacacg cccgtttgtt ctcccaaaga ccgcaatgcc gtctgaagtt tctgcccctg
     5941 actgcagacg ttgtgcaagg tttccggcgc gttgatgatg tcgaaggcgc ggctgccgac
     6001 cgcacacgcc atcgggttgc cgccgaaagt cgagccatgc gtgcccggtt ggaaggcggc
     6061 ggcaatcgtt tctgtcgcca gcatcgcgcc gatcggaaag ccgcagccca aggcttttgc
     6121 cgaactcaaa atatcgggaa caacgccgta atgttcatag gcaaacagcc tgcccgtatg
     6181 ccccatcccg gtttgaactt cgtccaaaat caacaacgca ttgtgccggt cgcacagacg
     6241 gcgcgcggtt tgcaaatatt ccgcagtggc gggcaggatg ccgctttcgc cctgtatcgg
     6301 ctcgatgatg accgcgcagg tctgttcgcc gacggcagct tccagcgcgg caatatcgtt
     6361 gaacggaacg tgcgtaatgc cttgcggcag gggtgcataa tccttgctgt atttcggctg
     6421 accgccgacg gacacggtaa acagcgtgcg tccgtggaaa ctgttgatac aggcgacgat
     6481 ttcgcttttt cctccgccga aacggtcgcg cgcatatttc cttgccagct tcaacgccgc
     6541 ctcattcgct tccgcgcccg agttgcagaa aaaaaccttg tcggcaaaac tgttcttcac
     6601 caatttttgc gccaattcct gcgccggacg cgtcgtatag atattggaaa tgtgccacag
     6661 cttgtgcatc tgcgtgttta aagcatcggc aagggcaggg tggcagtgtc ccagcgcatt
     6721 gacggcgatg ccgcctgaaa agtcaatata ttcacgccct tccgtatccc aaacgcggct
     6781 gcctgaagcg cgttcgggaa tcatcggtgc aaaggcgaaa ttgggggtca gatagttttg
     6841 cataattgct cctgattgcg gttttgctcg ggattatgca ccgtttttca aagcagataa
     6901 agggaaattg ccgacaatat cgggcagcgg taaaaataaa ccgaaatatt ttcaatcgga
     6961 tagatgaaaa atcaaaaaaa tttcgataaa atgcttgagg cgcggcagcg ttttgattta
     7021 gaatctcccc aatattttta tcttcagacg gcatttcatc atgcaaggca aaaaatttac
     7081 aaccgcttat tgctattggt accacacaga cgtgcggtac ttttttgcgc ttgcttgaaa
     7141 tccatcccat acgcaaaaca ggccgctcga aaatggggcg gcttttttgt taccttcaca
     7201 caggtcgccc gattcggcaa cacacgacag aatcaggaaa atgaccatga atgcaatgcc
     7261 ccaaaccgcc gcacaaaacg aaaccctgca catttgcagc attattgtcg atgatgcacg
     7321 ggatttttcc cccatgcttc tcgatgcagg gcgggacgac acactcatca gcgaatcgat
     7381 gattccgcaa atccgcactg ttgccgccct gatagccgcc gaacggcacg acttcagccg
     7441 cagcagcccc gccgagttta ccgatgccgc cgattttttt gccgcacgga ttctcgtatt
     7501 gggcgtgcga cgcttccatc tggacgtatc gctgcttcag attttgaaaa ccgccaacag
     7561 ccgcgcccgc cgctttgccg aaaaacaccg cctgtttttc acacccgcac aagccgaatt
     7621 gagcctgaac aaacacaaaa accgccgcct gctgaccgta gaaaccgaac acgaagtcga
     7681 aaacaaaggc aacccagtcg ccaacagcct cgcatttgtc cgcaaattgc acaccctgcc
     7741 cctgtaaaca tcacgatttg ccggcagaat gcttgccaaa attcccgacg gcgatacaat
     7801 aaaaccgatt ttccacccaa acaggacaca catgaaaaaa atcatcgcct ccgcgcttat
     7861 cgcaacattc gcactcgccg cctgccaaga cgacacgcag gcgcggctcg aacagcagca
     7921 gaaacagatt gaagccctgc aacagcagct cgcacagcag gcagacgata cggtttacca
     7981 actgactccc gaagcagtca aagacaccat tcctgccgaa gcacaggcaa acggcaacaa
     8041 cgggcaaccc gttaccggta aagacgggca gcagtatatt tacgaccaat cgacaggaag
     8101 ctggctgctg caaagcctgg tcggcgcggc ggcaggcgcg tttatcggca acgcgctggc
     8161 aaacaaattc acacgggcag gcaaccaaga cagtcccgtc gcccgacgcg cgcgtgcagc
     8221 ctaccatcag tccgcacatc ccaatgcgcg caccagcagg gatttgaaca cgcgcagcct
     8281 ccgtgcaaaa caacaggcgg cgcaggcgca gcgttaccgc ccgacaacgc gcccgcccgc
     8341 caattaccgc cgccccgcta tgcgcggttt cggcaggagg cggtaaaccc ggcgtgccaa
     8401 tgccgtctga agggctttca gacggcattt ttgcatttgt tagggacatt gttatgttgc
     8461 cgtttgattt tcagacggca ttttgtttcc aagcgtttga tgtcgggatg gcaattctga
     8521 tttacgtgcg ttggcagggt ggcattgtca tgccgccgtt gggttttcag acggcatcat
     8581 atcgaacagt caagccgtag ggcgagcatt cttgcccacc gttgcaaggg cgggattggg
     8641 tgggcaggaa tgcccaccct gcatctgaaa cccttccgtg tcattcccgt gcaggaagga
     8701 atctagatat ttgaatttac ggaaattttc aatcgttgcc aaagcggaaa agggttttta
     8761 ttacagccta atcctttggg tatcaaagcc gggcggtgtt gaaacattgc aaaaatgccg
     8821 tctgaaaccc gaaatcggtt tcagacggca ttggtttatg cggcaggttg gggcttagcg
     8881 gtctttgtaa cggcgttcgc ctctgcctgc aaaagaatcg ccggctttac gtttgccttt
     8941 gaagccttcg ccggtttttt tgaaaccgtc tttcttaaag ccttctttct tgaaaccttc
     9001 gccgcgcgtt ttgccgccga agccttcttt gcccggttta tgatcgccgc gccggccgcc
     9061 ggatttccta ttgccccagc cgcctttgcc ttttggctta ccgcctgcgg atttgcgttt
     9121 gcgggtcggt tccatgcctt cgatggtcag ttcgggcagt ttgcggttaa tgtatttttc
     9181 gattttgtgg actttgacgt attcgttcac ttcggcaaac gtaatcgcaa tacccgtgcg
     9241 gcctgcgcgg ccggtgcgcc cgatgcggtg gacgtagtct tccgcctgtt tcggcaggtc
     9301 gtagttgatg acgtgggtaa tggtcggtac gtcgataccg cgtgcggcaa cgtcggtggc
     9361 aaccaaaatt ttgcagcggc ctttgcgtaa atccatcagc gtgcggttgc gccagccctg
     9421 cggcatgtcg ccgtgcaggc agttggcggc gaaacctttt tcgtacaatt catccgcgat
     9481 gacttcggtc atcgctttgg tggacgtgaa aatcacgcat tgatcgatgt tggcatcacg
     9541 caggatgtgg tcgagcaggc ggtttttgtg acgcatatcg tcgcagtaca gcagttgttc
     9601 ttcgattttg ccttggtcgt ccacgcgttc gacttcgatg atttcagggt ctttggtcag
     9661 tttgcgcgcc agtttgccga ccgcgccgtc ccaagtggcg gagaacaaca aagtctgacg
     9721 gtcgctcggc gttgcttcca cgatggtttc gatgtcgtcg ataaagccca tgtctaacat
     9781 gcggtcggct tcgtccaaaa tcagcacttc caaacgttca aaatcaactt tgccgctttg
     9841 catcaggtcc atcagacggc ccggcgtggc gacaatcaga tcgaccggtt tgctcagggc
     9901 gcgggtttgg tagccgaacg atgcgccgcc gacgatgctg acggtacgga accaacgcat
     9961 atttttggca tacgccagcg cgtttttctc gacttgagcc gccaattcgc gggtcggggt
    10021 caacaccaaa gcacgcgggc ctttgcccgg tttttcgctg cgtttggtca gtttttgcaa
    10081 agtcggtaac agaaaggcgg cggttttgcc ggagccggtt tgcgccgaag ccatgatgtc
    10141 gcggccttcc aaagcaaacg gaatcgcctg cgcctgaatc ggcgtcgggc tttcgtaacc
    10201 ctcgctgctg acggcggaca agatgttttt atcgaggttc aaatcggcaa atttaataga
    10261 catggctatc cttggaagac aacaacgccc gcgtccgaaa ggttcagacg gcctgaagca
    10321 gggaagggta acgatacggg gaatgtgaag ttacagggtt gtcgcaagcg gcttgcttgt
    10381 ggtttacatc gacgacaacc tgcacagaaa ggcttggcaa atatgcaagc aacaaaagaa
    10441 acgcgcccgt aagggcggtt taggttggaa ggcgatggct tcgtatgaca agataagcgg
    10501 cggatggtat agggtttgcc cgaaacggtc aagcaatcgg gcgttaatta cagtaaaatt
    10561 gccgttttcc actttattcc gcctgaaacc aatgaccgac atcacaccgt ttgccaaccg
    10621 cttgggcaaa aacatcaaac accttatgaa atgggcgaaa cgcaacggca tcgaagcctg
    10681 gcgcatttac gaccgcgaca tcccccaatt cccctttgcc gccgatgttt acggcgatcg
    10741 aatccacctt caggaatacg ataccggctg gctgatgcgg cccgaagaat acgaagcgtg
    10801 gcttgccgaa gtcttggaag ccgtcgcctt cgttaccggt tttgcgcccg aacaaatccg
    10861 cctcaaacgc cgcgaacgcc aaaaaggttt gcagcaatac gaaaaaaccg gcaaggcggg
    10921 cgacgatttc gtcatcaccg aaaacggccg caagttttgg gtcaaccttg ataagtattt
    10981 ggatacgggg ctttttttgg atcatcgaaa cacgcgcaaa aaagtcggcg aaacggcggc
    11041 gggcaaacgt tttttaaacc tgttttccta caccggcagc ttcactgtct atgccgccac
    11101 cggcggcgcg gcatccagcg aaactgtcga tttgtctaac acttatctcg attgggcgag
    11161 acgcaatttt gaattgaacg gcatcgatac ggaacggcat aaaatcgtcc gcgccgacgt
    11221 gttccaatat cttcagacgg catatgggga aggcaggcgg ttcgacctca ttgtgatgga
    11281 cccgcccagt ttttccaaca gcaagaaaat gtccgacatc ctcgacatcc agcgcgacca
    11341 caaaaagctg attgacggcg cggtgaagct gctcgcttca gacggcattt tgtacttttc
    11401 caacaacctg cgcagcttcg tcttagacga cttggtatcg gaacaatacg ccgtcaaaga
    11461 catttccaaa caatccgttc ccgaagattt ccgcaacaaa aaaatccata ggtgctggga
    11521 aatccgccac aaatcttaag ggtgcgaaaa agccgccgga atcttccggc ggctttttcg
    11581 attgcgcttt atcaggcgat agaggcttcg acaaaggcgg tcagctgacc ttttgccaat
    11641 gcgccgactt tggtggcgac gacttcgccg tttttgaaca ccatcagggt cggaatgccg
    11701 cgcacgccga aacgggacgg ggtggcttcg ttgtcgtcga tgttgatttt gaccactttc
    11761 agacggcctt caaattcggc ggcaatgtcg tccaaaatcg gggcaatcat tttgcagggg
    11821 ccgcaccacg gagcccaaaa gtccagcagg acggggatat ctgcatttaa aacgtctttt
    11881 tcaaaagcgg catcgctggt gtgtacaatc aattcgctgc tcattatttt tccttttcgg
    11941 ttgggattgg cacgatagcg tgcaggatag ggcttgggca taaaaatttc aagtgggcgg
    12001 gcgggataat agtttttctg taccgcccca atcgcctttg caaattctaa aaaacggttc
    12061 ggacagtatt ttatttctga aaattacttt tattatcaaa atgtaaggaa tacgtttgag
    12121 gctgtacaga agcgcgcggg cggtgtatgc tccgtttaaa tagattctta aagtatgaat
    12181 gttcaaaacc aaacccgaaa ccctataaat aaaaggaacc ctgccatgac tgatttttcc
    12241 gtttgggaaa ctgctccctt tggtgcaacc gtcgatcata tcctgcaacg ctaccacaat
    12301 gtacaccgtg cacaatttga agaattggtg ccgctggcgc aaaaagtggc ccaagttcat
    12361 gccgatacct ttccggcgga aattgccgag ctgcttgcct atatgcagaa cgaactgctg
    12421 atgcatatga tgaaagagga aaggatgctg tttccgatga ttaatcaggg tgtcggtcgg
    12481 ggtgcggcga tgcccatcag cgtgatgatg cacgaacatg aagaacacga ccgcgccatc
    12541 gcaaggctca aagagctgac cgataatttc caagcgcccg aaggagcctg cggaagctgg
    12601 acgcggcttt acgctttggc caaagaaatg gtggaggatt tgaacgacca cattcatttg
    12661 gaaaacgata ttttgtttgc ccgcgtactc gattcttaag ggataggagc cggatatgtc
    12721 aatgccgtct gaaacacggt tttccgcttc agacggcatt tccacgtttc agcccaacaa
    12781 ttcgggcgga atgcggcaca cgggaatcgg gttgattttg tgctgcatcg cgcggtgcag
    12841 ccgcgtatag atttccagaa cttcgcgctg ccgcccttca aaatcttcgg gtttgcgcgt
    12901 gccgtacacg cccattgccc actccagttc gggatagctt gcgcccatct gttcttcgtc
    12961 ggtgcgttcc gtatcccaca ggccgtcggt cggcggggct ttttgaatcg cctcgtccac
    13021 gcccaatgct tcggcaagcc ggtaaacctg ggttttggtc aggtcggcaa tcgggctgat
    13081 gtccacgccg ccgtcgccgt atttggtaaa aaatcctaca ccgaaatctt caattttgtt
    13141 acctgtcccc gtaaccagta gtccgtgtat ctgcccgtag tagtacaggg tcagcatacg
    13201 caggcggctt ctggcgttgg cgagggaaag cggctgattg tcaaatgccg tctgatgaac
    13261 gccgacggtt tgttcaaagg tctggaaggt gtcggtcaga tcgaccgttt gtgcgcttac
    13321 attggcatat tgcccttgca gattgcggat gtgcagcctt gcccgctcaa gctggtcggg
    13381 gtgttggcgt atcggcatat ccagaagcag cgtggtgcgg ccggtgcggg cggcgagtgc
    13441 ggagacgacg gcggaatcga tgccgccgga aacgcccacg acgaaccctt ttgcatttgc
    13501 ctgagcggcg tatttgtcca accatcggac aatatgtgtg ataactgcct gcgtatccat
    13561 ttttcctcct gtcgaaaata tccgcatcat agcctgccgg cggttcgatt tgaatagatt
    13621 gcaggcaggt tgatgaatat ttttcccatt ccccgcttaa aaagtcatac gggcaaagtc
    13681 gggcggcaag atggcgcgtg ttataatatt gttgacaatt taggcgggct aatgccgcct
    13741 taggctttta aacatattca tattttttac tatttgattg attcgatgtc tgattttctt
    13801 cattctgacg tgttgtccgt ttccgagttg aacgcatttg ccaaaagtct tttggaaaac
    13861 caccttgccg gtttgtggat tgccggcgaa gtatccaacc tgacccgtgc cgccagcgga
    13921 cattattatt tctcgctcaa agacagccgc gcgcaggtgc gttgcgcgat gttcaaaggt
    13981 gcggcggcgc gtttggcgaa gcctttgaaa gaaggcgacc atatcgaagt atcaggaaaa
    14041 atcagtattt acgaggcgcg gggcgaattt caaattaccg tgaatgaggt gcggctcaaa
    14101 ggtttggggc agctttacga agcctacgag cggttgaagg cacagttgca ggcggaaggc
    14161 gcgtttgcgg cggaacgcaa aaagctgttg cctacccgtc cgcaatgtat cggcatcgta
    14221 accagtttgg cggcggcggc attgcgcgat gtcgttacca ccttgaaacg ccgcgcgccc
    14281 gaaattcccg ttatcgttta tccgacaccc gttcaaggca caggcagcga gtttcagatt
    14341 gcccaagcga ttaaaaccgc atcgcaacgc gccgaatgcg atgtattgat tgtctgtcgc
    14401 ggaggcggca gcattgaaga cttgtgggcg tttaacgaag aaccggtcgt gcgcgcaatc
    14461 gaagcctgca cggttcccgt cgtcagtggc gtgggacacg aaaccgattt cacgctcgcc
    14521 gatttcgtcg ccgatatgcg cgcgcccacg ccgaccggtg cggcggaact ggtcagcccc
    14581 aaccgccaag aatcgctgca tcgtctcgcc caagcgcaag gccgtctgaa aaccgttttg
    14641 gaacaacgct atttcgatgc cagccaaaaa cttgactggc ttgcgcggca aatccgtcat
    14701 ccgcgccaaa aacttgatga gcagcgcgct tcaatcggca agctggcgca aacgctgtct
    14761 tactctatga agcaaaacct ccgtgcccac accgcccgtt ttgaacgcca aacccaagcc
    14821 ctgcaacatt accgtcctga tgtttccgtt tgcaaaaaca acatcgtccg ccttcagacg
    14881 gcattgcccg ccgccttcag ccaactgctt acccaccgcc gccaaagcct gaccgcccaa
    14941 gccgcattgc tcgaagccgt ttcgccgcag cacattctgg agcgcggctt ttccgtcgtc
    15001 aaaaacacac gcggacaagt catccgcaac gccgatgttt tgaagcaggg gcagaagctg
    15061 cacattacct tcgccgacgg tgaaaccgac gtgcgcgtaa gcaaagaaca agggcagcag
    15121 gatttgttcg attgcattta aacccaatcg gaaaaaccgc tccccctccg ccgtcattcc
    15181 cgcaaaagcg ggagtccgga agcggaaagc cgccggggtt tatcagaaat gactgaaatt
    15241 caaaaaaccg tattcccgcc tgcgcgggaa tgacgattga tacgtttcga tatagtggat
    15301 taacaaaaat caggacaagg cgacgaagcc gcagacagta caaatagtac ggaatcgatt
    15361 cacttggtgc ttcagcacct tagagaatcg ttctctttga gctaaggcga ggcaacgacg
    15421 tactggtttt tgttaatcca ctataattta ttgaagatgg ctgaaattga aagttacaga
    15481 aatttataaa caaaaaacag caacatgcca ccgtcattcc cgcgaaagcg ggaatccgga
    15541 agcgaaaagt ggtgggaatg tattagaaat gactgaaact caaaaaaccg gattcccgcc
    15601 tacgcgggaa tgacgagtca gaagttactc gaaacttaaa aaaccgaaat cgaacgaact
    15661 ggatggattc ccacctacgc gggaatgacg attgatacgt ttcgataatt tattgaagat
    15721 ggctgaaatc caaagttaca gaaatttata aacaaaaaac agcaacccgc cgccgtcatt
    15781 cccgcgaaag cgggaatcca gtcccttgac cttaagataa tctttaattc gtcattcctg
    15841 aaaaagcggg aatccggaag cgaaaagccg caggaatttg tcggaaaaaa cagaaacctt
    15901 tccgtacacc cgaaatgttt cagacggcgc atcttggggc ggataaaaac ccgacccgat
    15961 atttttttat aattttcaat aagtttccat tgagcaaatg aaattttatt tttcaactga
    16021 cagaaagagg atgttatgaa gtttttagac cgtgaggcaa gcattgccaa gccgggtttc
    16081 aaccgttggc tcgtaccgcc cgcagcattg gcggtgcacc ttgccatcgg gcagatttac
    16141 gcctattccg tattcaacgc gccgctgacc aaacttatcg gcataaccga atcggcggcc
    16201 ggagattgga agctgacgac cgtaggttgg attttcagta tcgcactcgc gatgctgggc
    16261 gcgtcggccg ccctgttcgg tacgtggatg gaacgggtag ggccgcgcaa agccatattt
    16321 gccgccgcct gctgtttcag cctgggcttc ttcgtatccg cattcggcgt gcgtacgcac
    16381 aacctcttcc tgctctattt gggcaacggc gtcatcggcg gcgtaggctt gggtttgggc
    16441 tacatcgggc cggtttccac actgatgaaa tggtttcccg acaagccggg tatggcgacc
    16501 ggtttggcga ttatgggttt cggtggcggc gcaatgctgg cctcgccgct ttccgtatca
    16561 ctgatgaaca ccttttcaaa cgctgcttcg gttggggttg ccgaaacctt cgccgtattg
    16621 ggtctgcttt acctcgcact gatgatgttc ggcgcgttta ccatccgcgt acctgccgac
    16681 ggctggaaac ctgaaggcta taccgcgccg aaaacgcaaa acaagctggt cagcagcaat
    16741 catgtcaacg tgtcccaagc catgaaaacg ccgcagtttt ggctgttgtt ctgggtattg
    16801 tgcctgaacg taactgccgg catcggcgta ttgggtcagg catccgtgat gattcaggaa
    16861 ctcttttccg aaacctccat aggcaggcag gcagcagtcg gcgcaggtgc ggcggcaggc
    16921 ttcgtcagcc tcctgagcct gtttaacatg ggcggacgct ttttgtggtc gagcgtttcc
    16981 gacaaaatcg gacgcaaaaa cacctacacc atcttcttcg tactcggttc gctgctgtat
    17041 ttcgccgttc cctccatcgg cgagggcggc agcaaagccc tgttcatcat cggcttttgc
    17101 gtgattattt ccatgtacgg cggcggattt gccgccattc ccgcctacct gaaagacctg
    17161 ttcggcacct atcaggtcgg cgcgattcac ggacgcatcc tgctggcctg gtcaaccgcc
    17221 gccgtcatcg gcccggtact ggtcaattac atacgccaaa gccaaatcga cagcggcata
    17281 ccggcggcac aggcatacag cgtaaccatg tacatcatgg cgagcctgct gattatcggt
    17341 ttgttgtgca acctcgccgt taaatccgta cacgaaaaat accacgaaaa agacatcaag
    17401 acagccgcac gcagcggtaa ccccgacgac gaaaccgcca tatccgacgc ttaccttgtg
    17461 ggcgaaaaag tttccggcgg cggcatatcg gtctggtggc gttgggcatt ggccgtcata
    17521 ccgctcgcct acggcgtggt gatggtcttt gtcaaagcac tcgacctttt ctcctgaaaa
    17581 cgcccgaata aaatgccgtc tgaaacagta gatgtttcag acggcatttt tgtgttttgg
    17641 cgggtttagg cttttttgcg gcggcgttcg cccggcagca gcatgtccgc ccatttgatg
    17701 atgttggcga cttcggcggg gttgagttcg tagaactgtc cgcgtttgag gcggttgggc
    17761 agtccgatgg ggccgaagcc gacgcgcacg aggcggctga cggtgagtcc ttggctttca
    17821 aaaatgcggc gcacttcgcg gttgcggcct tctttaatca cgacgttgta ccatttgttt
    17881 gcgccttcgc cgccttgttc gtagatgcgt tcgacttttg ccaagccgtc ttcgagcctc
    17941 acgccttctt cggtgagcat ccgcatttgt tcggtggtca gcccgcccag tacgcgcacg
    18001 gcgtattcgc gttcgacttc aaaactggga tgggcgaaac gttggacgag ttcgccggag
    18061 gtggtgagga tgagcaggcc gctggtgttg atgtccaagc gtccgatggc gacccagcgg
    18121 ctgctggcgg cctgcggcag gcggtcgaaa atactgaccc tgccttgcgg gtcgtcgcgg
    18181 gaaacgattt cgccttcttg tttgtaatac aggatgatgc gcggcaggcg gtccgcccat
    18241 ttgagcttga tgatgctgcc cttgacggta acgtggtcgt cgggggtaac tttgtcgccc
    18301 agttgcgcgg ttttgccgtt gaccgttacc cagccgttgt tgatccattc ttccatttcg
    18361 cggcgcgagc cgacgccgga cgcggcaagc actttttgca ggcgttcggg ttccatgcgc
    18421 gacaggtcgc tgcggcgttc tttcaaatcg cgcgcgtgtt ccatgatttt ttggttggga
    18481 ttgcggacga cgagtttttt ggctttgtcg gcgcgctgtt tgggggtgtt ttgcagcttg
    18541 atgccgtctg aagctttttg tccgtaagct tgggcggcgg ttttgcgcgt ttcgcctttg
    18601 ggacgggctt tgcttttgaa cggtttggcg gtttttttgg cagacggggc tgcgccgtcg
    18661 cgccattggc gtttgctggt gggctgtttg gacatcattt ttcctaactc gcctgataag
    18721 gcggttcttc tgcggcgtgt gcggcaggac gggttgataa aatgccgtcc tcagtcggac
    18781 ggttcgatat tgtacctgat gcggcggttt tgcggatgaa atcgtcgctg cggctttggg
    18841 gacaaagttt gtgcaacggt tgaaatcggt ttgcgtgcgg gggtagaatc tttcaaataa
    18901 caagaggagc ggtaaatgga tttgcacaat attcgggaag attacagcaa acgggaattg
    18961 tcggaaggcg attgcgccga caatccgatc gagcagttcg agcggtggtt ggacgaggcg
    19021 gtacgcgcac aggtcaacga gccgacggcg gtcaatgtgg cggcggtcga cggacgcggc
    19081 agacccaaca gccgtatggt gcttttgaag gaggttaatt cagaaggttt tgttttcttt
    19141 acgaattatc acagccgcaa ggggcgttcg ctggatgctc atccatttgt ggcgatgacg
    19201 tttttttggc cggagctgga gcgtcaggtg cgcgtggaag ggcgtgttga aaggctggcg
    19261 gagaagttgt cggacgaata ttttgagagt cgcccgtatc agagccgttt gggtgcgtgg
    19321 gcaagcgcgc agagcgaggt gattccgaac aaggcggtat tggtggcaaa ggcggcggcg
    19381 gtcggactca aacatcctct gcacgttccc cgtccgccgc attggggcgg ctatattgtg
    19441 attcccgatt tgcttgagtt ctggcagggc agaccgagca ggctgcacga ccgcatccaa
    19501 taccgtttgc tggatggcgg ctggatacgc gagcggctgt cgccttgaac aggaaaaaac
    19561 atatgccgtc tgaaaaccgg aatcgggttt cagacggcat tttttcacgg gaaaacacgg
    19621 acaggaagtt tttgtgttcc gaacggaaag cccgaatttt ctttgatacc ggggaattat
    19681 gatgcggacg gcgtgaatgc gtcggagaaa aataagtttt ccggcagctt atgctgttgc
    19741 acaaacagat tttttgcttg ttcggtcatg gccggagagc cgcaggcaaa tacttcgtat
    19801 tccgacagat cggggtggtc ttgtgccgcg atgtcttgta cgtggccttt tttcccctgc
    19861 cagccttctc cggggcggga caatacgggg gtgaagcagg cgtttttcag acggcatgct
    19921 aacccttgtg cttcttcgag ggcatacaaa tcatcttgat gacgcgcgcc ccagtagaaa
    19981 tggacggcgc ggctgctgtt ttggcggata aggtcgagca ggatgctgcg gatgggggcg
    20041 tagcctgtgc cggttgccag caggatgacg ggtttgccgc tatcttcctg cagggtaaac
    20101 gaaccgagcg gacctttaac gcggacgatg cctttttctt tgactttggg ttcgctgccg
    20161 aaaatcattt ccgagcagac accgtttttg cgcctgcgga tgtgtagttc caaaatgcct
    20221 tcttggtcgg gcggattggc gatggagtag ctgcggctga cgttgcccgg cagcagtaaa
    20281 tcaatgtatt gcccggcgta gaaggcaaac ggcggggctt tgggcagggc aagtttcagg
    20341 agggcgacat cgtgtttgaa aataatactt tcgatgcgtg cgggcagggt gcggacgggt
    20401 agggcatcgg ctttgtagcc ggggatgttg atgctgatat cgctttgcgc ggtggtgcgg
    20461 cacatcaaaa tcttgccttg cgctttttct gcttcggata aagcctgttc cgagtgtccg
    20521 tccatttgaa tatcgccgct gaccagttcg gctttgcatt gtccgcagac accgcttttg
    20581 caggaatgag gcaggttgag gttttgtcgg gcggcagcgg ccaaaacggt ttcgccgtcg
    20641 ttggcggcaa aggtggtttg gtcgggcagg gtaacggtgt ggttcatgga atattgtttt
    20701 ttatgctgtt ttaatgtggt cagactgtga aaatgccgtc tgaacgtcgg atttgggttt
    20761 cagacggcat cttgcttgtc aggcaagttt ggctttaatc agctcttgaa cctgcgcggg
    20821 gttggctttg cctttgctgg ccttcatcac ttgtcccaca atcgcattca gggctttttc
    20881 gttgccggat ttgaactgtt ccacggcttt ggcgttgttt gccagcactt cgtccaccat
    20941 ggcttcaatc gcgccggtat cggtcatttg ctgcaaaccg tgtttttcaa tgatttcggc
    21001 aatggtggct tcggattctg cccacatggc ttcaaaggct tttttcgcta atttgctgct
    21061 taatgtgccg tcggcgattt tgcctaccag cgcggcgagg cgcggagcgg taatcgggct
    21121 gtcggcaagt tccatgcctt ctttgttcag tgcggcggcg agttcgccgt tcatccagtt
    21181 ggcagtcggc ttgccttgtc cgctctcttt ggcggcttct tcaaaatagg cggcctgtgc
    21241 gcggcttgcg gtgagcaggc gcgcgtcgta ttcggacacg ccgtagtccg ccacgaaacg
    21301 cgctgccatt tctttcggca gctcgggcat ttctgctttg gctttttgca tttgggcatc
    21361 tgaaatgatg acgggcagca aatcggggtc ggggaagtag cggtagtctt gcgcgtcttc
    21421 tttcaggcgc attacgcggg tttcgccttt ttcgggatca aacagcatcg ttgcctgctg
    21481 tactttgccg ccgtcttcca aaatctcgat ttgcgcttct gcttcgtaat taatcgcctg
    21541 ctccaagaaa cggaaggaat tgaggttttt aatctcgcgg cgcgtgccga attccgcttg
    21601 acctttcggg cgaacggata cgttggcatc gacgcggaac gaaccttccg ccatattgcc
    21661 gtcgcaaatg ttcagccagg ttaccaagct gtgcaaggct ttggcgtagg caacggcttc
    21721 ggcggcggag cgcatttcgg gttcggatac gacttccaat aaaggcgtgc cggcgcggtt
    21781 caaatcgata ccggtcgcgc cgttcaagcc ttcatgtacg gacttgcccg cgtcttcttc
    21841 catatgggcg cgggttacgt tgatggtttt cacatcgtcg ccgactacga tttccaattt
    21901 gccgtgttcg acaatcggta agtccaactg gctgatttga tagccttttg gtaagtcggg
    21961 atagaagtag tttttacggt cgaacacgtt tttccggttg attttcgcat ccaaagccaa
    22021 gcctaatttg atggcttttt caacgacttc tcggttcatt accggcagta cgcccggcaa
    22081 agcacattcc actacgccgg cgtgcgcgtt gggttctgcg ccgaatgcgg tcgatgcgcc
    22141 gctgaagatt ttggatttgg tgttcaattg gacgtggatt tccaagccga ttacggtttc
    22201 ccaggtcata agagcttctt tctctaaaat atcaattcga tagtcttcgc gtcaggctgt
    22261 ccggcggagc ggtttttccg tttggatgcc gtctgaaatg ccgcgtgctt ctgttttcag
    22321 accgtccttc atctctgcaa ccatgttgtc cagcatttca taacgcttgc ggtacatcga
    22381 gcgttttttg ctttcgatgt cggtaaggtc tttgcgggcg ggggtttggg ggagatgcca
    22441 gtagccgtcc cgttccaaac ttgcgccgta ttcctgccag aatgcgtcgt aattcatttt
    22501 gacacgcttt ttaagtttcc agcgcagttt gacctgatgt ttttgtgcaa tgcccattgc
    22561 gccgtccaag ccgagtacgg cggcgaaata ttgcagggcg gttaccatca gttgttgggg
    22621 acgcaagccg tgaagttgtt tggttatgcg gcggacagtg tctttggctt cttcacccgc
    22681 aggcccttgt acggaggctg tcagcaggtg tgtgccgaca aaggcgaaag tcgccatata
    22741 cagccggttg cctgcttcgt cgcgcaaaga taaagaccac gcgccttctt cgacgcagtt
    22801 gtcgttgcgg ttgagccaca agctgatgcc gtctgaaagg tgcgccaaga ccaaatggaa
    22861 gcggtagtct tccatttggt gcaggatgtc tgtgccgaac agtttttccg ccatgagaaa
    22921 atctgccgtc atcgcatcta aacggcgttt gcagttaaaa cgcctgtcaa caaattcgcg
    22981 cagcagcgga taggcatttt gcgggcagtg gaggaacagc ccctgacgga taggggaggc
    23041 gttgacaaac tgctcgaagg cgtaaatttc tttttttccg aaaaattttc gcaatgtgta
    23101 ttttaaatgt tgcagccgat ataaaggcgc atagctgtaa acggtgcgaa aatcggggaa
    23161 ggtaaaggtg cggttctgct tcattcgggt cgtttgccgt gccaatcgct gttgagttgg
    23221 atttgatgcg ccgcaccgag gattttggct tcggcgaagt agttgccgac aagctgaacg
    23281 ccgacgggca gtccgccgcc gctgaagcct gcgggcaggg tcaatgcggg cagtccggcg
    23341 aggttgacgg cgatggtgta gatatcgctc aagtaggttt caaccggcga agcatccgct
    23401 ccgatttttg gggctgcagt gggtgcggtc ggcgcgagga tgaggtcgca ccgtgcaaat
    23461 gccgtctgaa aatcatcggc aacgaggcgg cgcagttttt gggctttgag atagtaggca
    23521 tcgtagtagc cgtgcgacag tacataagtg ccgatcatga tgcggcgttt gacttcgctg
    23581 ccgaaacctt cggcgcgggt tttgccgtac atttcttcca aatcggcgaa ttgggcggca
    23641 cggtgtccgt aacgtacgcc gtcgtaacgt gaaaggttgg tgctggcttc tgcggaggcg
    23701 aggacgtagt aggcggggat ggacagcttg gtttgcggca gggaaacttc aatcaattcc
    23761 gcgccttggg ctttcagcaa atcaatggtg ttttgcaatg ccgtcagaac atcggcgctg
    23821 ttgccttcgc cgaaatattc tttgggcagg ccgattttca aacctttgag cggttggttc
    23881 aaatcgcggg tgtagtcttc tttttcgcgc tcgaggctgg tggagtcttt ggggtcgaaa
    23941 cctgccatcg cgtttaacag aatcgcgcag tcttcggcag tttgcgccat cgggccggtt
    24001 tgatcgaagc tggaggcgta ggcgaccata ccgaagcggg aaaccgtgcc gtatgtgggt
    24061 ttgatgccgg taatgccgca gtgcgatgcg ggttggcgga tagagccgcc ggtgtccgaa
    24121 ccgagcgcgg caggggcgag gcgcgcggca acgacggcgg cggaaccgcc tgacgaaccg
    24181 ccggggacgt gctcaagatt ccatgggttt ttggctgcac cgtagaatga gttttcattg
    24241 gtcgaaccca tagcgaactc atccatattg gtgcggccga gcgttaccat accttcgtcg
    24301 agcaggtttt ggacgacggt ggcggtgtag ggggagatga agttgtcgag cattttggaa
    24361 gcgcacgcgc tgcgccagcc ggtttggcag aaaatatcct tgtaggcgac gggtacgccg
    24421 gtaagcgcgg aggcgttgcc ctgcgcgata cgttcgtcgg cggcacgggc ttctgcaagg
    24481 gttttatctt ggtcgatggt gatatagccg ttgagggcgg gatttttttc ggcgatggcg
    24541 gcaaggtatg cgcttgccag ttcgacggcg gaaatctgtt tggactgcaa caggacgctt
    24601 gcctgtttca atgtgtattg ggtcataaat cttccatcct taaagggctt cgggcggtat
    24661 tgctgatgcc gtctgaagcg tattcggatt attcttcgat aacttgcggt acgatgtaca
    24721 ggcggtcgcg tacttccggt gcgaccgcct gatattcggc ggcgcggtcg gtttcggtta
    24781 cttcgtcttc gcgcaggcgc agggcggcct cgtgcgggtg cgccatcggt tcgatgccgt
    24841 ctgtgttgat gttctgcatc tgttcgacca tagtgaaaat gtcgtttaat tcttgaagcg
    24901 atttttcttt ttcttccgca gtcaggtgca atcgggagag tcgggcgatt ttgtctacgt
    24961 cggcaagtgt cagtgccatg aaaagcatcc ttgtctgatg gtaaagatac cgtcgttcgg
    25021 gtatgatggg gcgtattgct tgaattttta attataacgg aaaaatccgt tgcggcggca
    25081 atttgcagca tcggatgcct gccgcacggg tttgaaggag ggggaaataa tgggattggg
    25141 catggaaatc ggcaagctga ttgtggcttt tttggtgctg atcaatccgt ttagcgcgtt
    25201 gtcgctttac cttgacctga ccaacgggca cagcacgaag gagcgcagga aggtcgcgcg
    25261 gacggccgcc gttgccgtgt ttgccgtgat tgcggtattt gcgctgatcg gcggtacgct
    25321 gctgaaggtt ttgggcatca gcgtcggttc gtttcaggtc ggcggcggaa ttttggtgtt
    25381 gctgattgcc atttctatga tgaacggcaa cgacaatccc gccaagcaga atctcggcgc
    25441 gcagccggaa acggggcagg cgcgccccgc ccgcaatgcc ggagcgattg ccgtcgtgcc
    25501 catcgccata ccgatcacca tcggcccggg cggtatttcg accgtgatta tttacgcttc
    25561 ggcggctaaa acatacggcg acatcgcgtt gattatcgcg gccggtttgg tggtcagtgc
    25621 gatttgttat gccattttaa tcgttgccgg gaaggtcagc cgcctgctgg gcgcgacggg
    25681 gctgacgatt ttaaaccgca ttatgggtat gatgctggcg gcggtatcgg tggagattat
    25741 tgtgtcggga ctgaaaacga tattcccgca actggcaggt tgattcgatg tttcacagtg
    25801 tcaatgtatt tacgggcgaa acgctttacc gccgtccagc tcaagattat gcggagtttg
    25861 aacggcggct ggcggatttg aaaatgcgcg gcggggcgtt cgcgcaactg ggcgtaaccg
    25921 aacgtgccgc gcgcctgcaa aaatttgccg accgtttgga ggcggagaaa gagcgttttg
    25981 cggaaatggt gtgtgaggaa gtcggacgct gcttgcacga atgccgtgcg gaaatcggca
    26041 agtctatcga actgatacgc tattacgccc gccttgcccc cgaactgctt gcccacaaaa
    26101 ccatcgcgac gcaggcgagt ttgagtcagg tgcgcttcga gcctttgggc gtggtgtttg
    26161 ccgtcatgcc ttggaactat cccgtctggc aggtattgcg tttcgccgtt cccgctatgt
    26221 gcgcgggcaa cgcgtgcgcc gtcaaacccg cgcccagcgt ggcacgcgtc agtcaggcac
    26281 tgttcgattt ggcttcagac ggcattcctc tggcaggcgt gtggctggat gaggcgggca
    26341 cgctcaaggc ggttgaagat accgatgcaa tggcgtttac cggttcaacg catacggggc
    26401 gcatccttgc ggcacacgcg ggcgcaaacc ttaagaaaac cgtgttggag ctcggcggta
    26461 gcaacgcctt tatcgtgatg cccgatgctg atttggagcg tgccgccgca gaagcctgtt
    26521 attcccgttt ccgcgatgcg gggcaatcgt gtaacgccgc caagcgcatc atcgtaaccg
    26581 aagccgcagc cgaccgcttt attcagctgt ttctcgccga atgcgccaaa ttgaaaatgg
    26641 gcgacccgaa acatcccgat accacgcttg caccgctgca ccgcgaagat ttgcgggacc
    26701 gggttcacgg gcaggttgaa gatgccgttt caaacggcgc ggtgtgcctg accggaggca
    26761 aagttccaca ggggtcgggg tggttttacc ctgcgacggt tttagacagg gtaaatcctg
    26821 cctgccgcgt ctggagagaa gaagtattcg gccccgtcgc cctgattttg cgcgccgaaa
    26881 acgaagaaca cgccatctgc cttgccaatg attccccgtt cgggctcggt gcctgcattt
    26941 ataccgccga tactgaacgc gcctggcggt ttgccgaaaa aatacaggcc ggatcggtgt
    27001 ttatcaaccg ccataccagc agcgatttgc gcctgccttt cggcggagtc aaagattccg
    27061 gttacgggcg cgaactgtcc gaattcgggt tgtacgagtt cgtcaacgtc aaaacctact
    27121 ggcagaaata aacaaacccc gtgccgcttc aggcggcatc gggtttgcgc tagagccgat
    27181 taacggcagt atttgttcac atcgttattg tatttacgga tcaaatcatc cttgtttttc
    27241 gcatttgagt ttcccaccgc cttcaggttc atttttgaaa tccggcagtt ttcttctttg
    27301 ttctgccgtt cggtttcggc aatttttttc ttttcttcct caagctgccc gtttttctcg
    27361 gcgatatcct tttcgttttc cttcgcactg tccgcattcg tatcgacggc aggtttgggc
    27421 ttgaccgccg gtttggtttg gagcgtccgc gggttgagga tttggctctg gtcgggatga
    27481 agctgtttcg gcacatccga atagctgttg ccgccgccgt ctttccaagt aaagacggcg
    27541 gctccggcag gcgggacggg caggaaagag gcgagggtaa atgcgatgac ggataaagca
    27601 aagttcatta gggtttcctt gatggctgac tgcccgggca gaatcgggat tggttcgggc
    27661 ggtgtctttt ccgggttcgg gtcaaagtgg ggaagacact ccgccttaat atggtgcttt
    27721 atatattggg gtaaaacaga ttcccaaaaa tatagtggat taacaaaaat caggacaagg
    27781 cgacgaagcc gcagacagta caaacagtac ggaaccgatt cacttggtgc ttcagcacct
    27841 tagagaatcg ttctctttga gctaaggcga ggcaacgccg tactgatttt tgttaatcca
    27901 ctataattga tgaaatgccg tctgaacgct ttgaaaaggg ttcggacggc attttgttca
    27961 aaccgagacc tttgcaaaaa tagtctgtta acgaaatttg acgcataaaa atgcgccaaa
    28021 aaattttcaa ttgcctaaaa ccttcctaat attgagcaaa aagtaggaaa aatcagaaaa
    28081 gctttgcatt ttgaaaatga gattgagcat aaaattttag taacctatgt tattgcaaag
    28141 gtctcaaacc ggtttatttg cgttgcaata cggcggcgaa gaagccgtcg gtttggtgtc
    28201 gggcggaatc gaggcgcagg tattttccgg tatccaaatc aactttcagg ctttgcagca
    28261 gttcggcgca gttgacgagt tcaaattcgg gatgttcgga caggaaacgt tcgacttgca
    28321 gttcgttttc ttccggcaac acgctgcagg tggcgtacac caagcggcct tgtggtttca
    28381 ccagtttgga ggcggcatcg aggatgctgt gctgctgttc caaaaggttg gcgatggtct
    28441 cggcggactg gcggtatttg aggtcgggat tgcggcgcag cgtgcctaag ccggagcagg
    28501 gcgcatccac taaaacgcgg tcggctttgc ctgccagtcg ggcgatacgg gtatcgtgtt
    28561 cgctgctgat gcgttcgggg tggatattgg tcagtccggc gcgggtcatg cgcggtttga
    28621 ggttggcaag gcgtttttcg gcgatgtcga aggcgtagat tctgcctttg ttcgccattt
    28681 gcgcaccgac agccaaggtt ttaccgccgg cgccggcaca gaaatcaaca atgatttcgc
    28741 cgcgttttgc gcccaacaat aaggcaagca gctggctgcc ttcgtcttgg acttccagtg
    28801 tgccgtctaa aaacagttcg tgtttgttaa gcgcgatttt gtttttcagg cggatgcccc
    28861 aaggcgaata aggggttgcc tctgcatcgg cactttcggc ttgcaataat ggcaacactt
    28921 tatcgcgttt gcctttcaaa gtgttgacgc ggatgtcgag cggggcaggc tggttgatgc
    28981 tgcggccgaa ggcgaggatt tcttcttcac gccaatgctg ttgcagttgt tcgaccagcc
    29041 attgcggcaa ttctgcggcg gtattcaggc cgtctgaaaa ctcggtttta cgggctttca
    29101 aattgccgag gaacgctgtt tcttcttcat caaacaggtc tttgatttgg ctgatgttgg
    29161 tgcttctgcc gagaaccagt gcggcgagtg cggctttgcg cggctgtgcg tgcggacggc
    29221 gcagggcagt gctgattttt tgatagtggc gcagcgcggc aaaggcggtt tcggcgattt
    29281 cgtggcggtc ttggcggccg agctttttat gttcgcggaa ataggcggag aggacggcat
    29341 cggcaggctg tttgaaagtc agcatttcag ccaaaacttt ggcggtatgg tcgagttgtg
    29401 cggcgttcat aatgtaatgg gttctcttac tgtgggttat tcataatcaa tctaacgtcc
    29461 ttaaaataac aatagcatct ttatcattac ttagtattct atccgcaata agaaagatgt
    29521 gttaaaagtg cgcaatcggg atttgtctaa atttctccgt taactacaaa ggcagcctga
    29581 aaaaagttct attttcaggt cgcttgaaca gcatccgata taatcacatc agcgatttca
    29641 ttttgtaatc actccccaaa acatgaggaa aaaaacaaaa tttattttct tcgttcagta
    29701 tatctatcct aaatatgcca tcactccatt gagtttttaa tttgtatttc gctcttgtta
    29761 aatgtttttc tgtttgccga tttcttttgc taatgtaaaa aatactctac cactctcatt
    29821 ggttaaagtt ttcaagtatt catcaacatc agtaacatta ataacaactg tttcatttgt
    29881 atgtttatta aattctaaat caataataat attcccatta accaatattt catatatatc
    29941 ttcttcttca gggagcatag acaaacaata agcacttgaa gctgaaaact cttttttcag
    30001 atactgaaga agaaaagtat ttttaattaa aatattatta aatttatcta atgattgctt
    30061 gacttcttta gttgtccaat ttttaacatt attcttcatt gtattctacc tgggtcgtag
    30121 ttattaaatt accatactta tttgtttgga tcgtcataat attagttggc atgttgttgt
    30181 tatatttatc atatccaata tccttattaa ctcggatgac tctttcataa attgtatggg
    30241 aaatgagatt tccatcacta agcctctcaa tagatatacg cgttaatgtt gggaaagggt
    30301 ttcagacggc cttcataatg cgttcgattt cgtgccaaaa gccgtccggc cgacattcca
    30361 aaacggcaat caagccttgg tcgatacggc ggatttcggt ttcgttcaat gtttcggttt
    30421 cggcggcacg cgcaggtgcg aggtaggcca tgcggtcgag cagatggtag cggacttctt
    30481 ggcgttcaaa cccgtattcc gcccaatctt gaatatagac gtcgcgccag ccgtatggat
    30541 taagcggcgg ctcaaaagca tggaaacctt gcggaaaaaa tccgatgccg cgcacgatgg
    30601 aaacgggttt tacgtcaagc ggcagaccgt gttgccgcaa ggttcggatg ccgtctgaag
    30661 tgtgcggcag accgagttgg gcggtcagtt tggcggcttt tcccaacagc gtgtctttgg
    30721 ggtcgagtcc gcgcatgtct tcgagcctgc ccgtgccgcc gccgtaatat ttgcaggtca
    30781 gctcgatatg gtagggcttg ccgttaagcc ttaccacaaa atccgccgcg ccttgcgtat
    30841 tgccgtccga accggaaacc gtgaggttgt gcgcgagcag ttcggcgtgt ggcgcgttgg
    30901 taaaccaaaa tgccagcagt tcttcggcgt aaatgccgag gcggtgtccg aacggggcgc
    30961 gtcgggtgag gtgttccgtc agcggcgcgg gatcggcatc caatgccaaa agatagcgga
    31021 aaccgcgttc ccccaatagt tcgcgcacgc ccaattcgca accgctttgc cacaaaggcg
    31081 gcgcagtcag cagcgaggcg aggtcgcgga cgggttggct ggtgagcttc caccataatg
    31141 cgtctagggc gtaattcatg cttatccgaa tatcagtcat gccgtctgaa aagctggaaa
    31201 tgttttcaga cggccttaat cagtcttttt tatggatacg atggctgacg gtattgaaaa
    31261 aaccgcgcag gatatcgatg tcttcggttt gcgtgttggc gcgtccgaac aggctctgca
    31321 tacggcgcat cagacgctcg ccgttgcggc ggttgaaaaa gccgatgtcg ttcatcacgc
    31381 tttccatgtg ggcgaccatg cctttgattt gctcgtgggt cgcagcgtgg tcttcttgtt
    31441 gaagatgggt catgggcgaa ccggtttggc tgaagatttc gtagcacacg acctgcacgg
    31501 cttgggcgag gttgagcgag aaatagtcgg gattgccgtt gatggtcatc agtcggttgc
    31561 aggcttggac ttcttcgatg ctcaagccga aagtctcgtt gccgaaaacc agtgccactt
    31621 tctcgcctcg gtttgcggtc tgcagtaatt cggataccaa atcgcgcggg gtttgcagcg
    31681 gcgcagtaat ttcgcggcgg cggctggtca gggcgcaggc gatggtggtg tcggcaaggg
    31741 cttcgtccaa agaagcggca atggtggcat tttccaaaac gtctgccgcg ccggaagcga
    31801 ggatgaagct ttcttccggt aatttaaacg attgaggatg ctccgggtca aacacgggcg
    31861 ggttttccgt catcggcgtt gccatcagat ttggggcgac gatggtcagt ttgtgcagac
    31921 ccattgtttt catcgcgcgc gcggcagagc cgatgttggc gggatggctg gtgcgcgtga
    31981 ggatgatgcg gatgttgtcc agataagcgg gcagggcggg tttgagagta gtcatgttcg
    32041 gttttcggtc ggaatggaat agggtataat gcgccgtctt tttcgttcgg acggtcaaat
    32101 gccgtctgaa atgttcttta acaacgtcgg aaatttaacg ttgcgcctga agcagacacg
    32161 cgtcgggcgg tattttaccc gatttggcag gatttacccc aaccaaataa actccgattt
    32221 tgccgctccg aaggactgcg cgtccgaacc ggcggtatgc cacccttaag gaaatctgat
    32281 gaatccgttt ttgaatacag cctttaaagc cgcccgccgt gccggtcaga tgatgatacg
    32341 cgccgcgggc aatctcgatg ccgtcaaaac cgacagcaaa gcattcaacg attttgtttc
    32401 cgatgttgac cgcaattccg aaatcatcct ggttgaggct ttgaaagaag cctatccgca
    32461 ccacaaaatc acttgcgaag aaagcggctc ccacggtaaa gccgcagccg aatacgaatg
    32521 gattatcgat ccgctcgacg gcacgaccaa cttccttcac ggccatcccc aatacgccat
    32581 ctctatggca ctcctgcaca aaggcgtgtt gcaagaagct ttggtgtacg cccccgaacg
    32641 caacgacgtt tacatggctt cgcgcggcaa aggcgcgttg ctcaatgacc gccgcatccg
    32701 cgtttccaac cgcatcgaat tgaaccgctg cctgatcggt accggctttc ctgttgtcga
    32761 tcaaagcatg atggacaagt atctggcgat tttgaaagat ttcttggcaa aaaccgccgg
    32821 cggccgtcgt gaaggcgcgg cttctttgga tttgtgtgct gtggcgactg gtcgttttga
    32881 cggctttttc gagttcaacc tcaaaccttg ggatattgcc gcaggcgcat tgattgttca
    32941 ggaagcgggc ggtatcgtaa ccgatatgac gggtgaagac ggctggctgg aaagcggcga
    33001 tattgtggct gccaatccca aagtgctggc gcaaatgttg aaaatcattt ccgcacacgt
    33061 ttaaatttca gcccgctccc gggaatgcgg gaaaacgggc gggtatgccg tctgaagtat
    33121 cgcgccgata tttcagacgg tatttttatt ggtaacaaga gtgggaaggt ggaaacggct
    33181 aaatgttcca aactgccgag gatggaaact aaacggagaa ccctgtgcaa tttgtttata
    33241 gtggattaac aaaaaccagt acggtgttgc ctcgccttag ctcaaagaga acgattctct
    33301 aaggtgctga agcaccaagt gaatgggcaa agccaacgcc tttaccgcac cgattaccgt
    33361 cgtcaattac gacgaacaag ccctcaataa caccgaagcg cgtactttgg tggatgccgt
    33421 agcgaaaaaa gatgcttccg tttggcagtt cggcggcgaa agcaacacgt tgaccggact
    33481 gtatttcaga ggttatcagc ttgatgcgcg ccaattcagc gtcaacggtt tggcaggtat
    33541 gtacggcacg caaggcacgg ccagcgtgca agttggatcg gcacaactga ttaaaggcgc
    33601 atccactgcc gtaaacggta tggatcctga aggcgcggta tccggttccg tcaacatcga
    33661 aaccaaaaaa gctgccgatg aaggcaaccg caaaatcggt ttgggctggt tcagtaacaa
    33721 ccgcgcccaa ggtacgttcg acttgggcca acgtttcggc gaaaacaaag cattcggcgt
    33781 gcgcgccaac ggcaaactgc gccacggcga caccccgcgc cacggttaca gcgaagacaa
    33841 caaagaattt gcggtaaatg ccgactatcg cggcgaaaca ctgcgcgtag cgttcgattc
    33901 catctacgca aaacgcaaaa ccaacggcgg tcgcgcgcgt atgcaggaca ttcaaaacgc
    33961 cggcggacgc ttgtttggcg cgcccgatgg taaaaccaac ctgctgcctt cttggaactg
    34021 gcaaaatacc gccggccaaa ccaatatgct tacgtttgaa tgggatgcgt ttgataatgc
    34081 acagattaca ggcggtatcg gctacaacaa ggcacgctat tacggcacgc tgatttcccc
    34141 gaccgtatgt ttgaatgcta ccagcacttg taccgatatg caaaacacaa acgccagcgg
    34201 caaagtaacg gcacgcaact atgactacaa taccggtact gcgcgcctga ccgaccaata
    34261 tttccgcaca ttgagtatga acctgaccgc acgcggcgaa tttgaaaccg gcccggtaac
    34321 acataactgg agtatggctt tcgaccgcgt tatccgccag cggaaaacca taaacggcag
    34381 cgggaacggc aacagcaaga tagaagtgaa ggcaaacgaa aatattgcga atcaattggc
    34441 atcgtttaca gccgactatc ccaattcttg ggagaactct gccaacttgg atgccaatat
    34501 caaagtcaac agcctggctt tgtccgacac cttgggcttc gtggataaca aataccgcct
    34561 gactttgggc ggacgtttcc aaacagtcga atataccgac aaaaaatcac agagcggcga
    34621 tgccaaacgt ttcagcccga tgctgatggc ggcgtgggtg ccgcaacctg atttggttgt
    34681 gtacggcaac tatatggaag acttggagcc tgccgacatc aaaaccgatg attccggcga
    34741 aatgacaatg gcgaaaccgc gtgtcagccg ccagtttgaa gtgggcgtgc gtaaaaactg
    34801 gggcaatttc gtaaccacgt taaacgcgtt ccaaatcaaa cgcccggcta ctggcgcggt
    34861 catacaacta ccaagacaac aaaaggggta acaacaacgc tgacctatgg caacaattcc
    34921 gatttcgccc gctataaggc gcaaggcggc gtagccggcg acgagcaagg tatggaacgc
    34981 aatcgcggta tcgagttcaa tgcctatgct aacctgttaa acaaaaccct gcgtccgact
    35041 ttgggcctga tgtatctgca atcgaccgtg aaagactacc caaattcacg cgatatgctg
    35101 gttaacggcg tacaagtcgc caatccgcgc gtaattgcca aggcaggttt ggaatgggat
    35161 acaccgtttg ccaaaggctt gactttaaac agcaatgttt cgtatttcgg caagtcttac
    35221 caagacacgc aaaaacaata cgccttccca tcctatacct tggttgatgt aggcgcgcgc
    35281 cacaaaacca agctgggcaa aaatacgttg accgtcagca gctcggtaga aaacctgttc
    35341 aacaaaaact actggcaggt acagcgcgga caatttgacc gcagcttcgc cgtcgtcggt
    35401 atgccgcgca cttactggct gaaggcggaa ttggatttct gatttctccg catccggaaa
    35461 atgccgtccg aacaggtttc agacggcatt tcttttaaag aaatatggcg ggatacgctt
    35521 aaataatgct attctagtgc ctttgaaacc tgcttgtttg aagtgatgaa aaaacctttg
    35581 atttcggttg cggcagtatt gctcggcgtt gctttgggga caccttatta tttgggtgtc
    35641 aaagccgaag aaagcctgac gcagcagcaa aaaatattgc aggaaacggg cttcttgacc
    35701 gtcgaatcgc accaatatga ccgcggctgg tttacttcta cggaaacgac ggtcatccgt
    35761 ctgaaacccg aattgctgca taatgcgcag aaatacctgc cggacaacct gaaaacagtg
    35821 ttggaacagc cggttacgct ggtaaaccat atcacgcacg gcccttttgc cggtggattc
    35881 ggcacgcagg cgcacattga aaccgagttc aaatacgcgc ctgaaacgga aaaagttctg
    35941 gaacgctttt ttggaaaaca agctccggtt tcccttgcca ataccgttta tttcaacggc
    36001 agcggtaaaa tggaagtcag tgttcccgcc ttcgattatg aagaactgtc gggcatcagg
    36061 ctgcactggg aaggcctgac gggggaaacg gtttatcaaa aaggtttcaa aagctaccgg
    36121 aacggctatg atgccccctt gtttaaaatc aagctggcag ataaaggcga tgccgcgttt
    36181 gaaaaagtgc atttcgattc ggaaacttca gacggcatca acccgcttgc tttgggcagc
    36241 agcaatctga ctttggaaaa attttcccta gaatggaaag agggtgtcga ttacaacgtc
    36301 aagttaaacg aactggtcaa tcttgttacc gatttgcaga ttggcgcgtt tattaatccc
    36361 aacggcagca tcgcaccttc caaaatcgaa gtcggcaaac tggctttttc aaccaagacc
    36421 ggggaatcag gcgcgtttat cgacagtgaa gggcagttcc gttttggcac gctggtttac
    36481 ggcgatgaaa aatacggccc gctggatatt catatcgctg ccgaacacct cgatgcttct
    36541 gccttaaccg tattgaaacg caagtttgca caaatttctg ccaaaaaaat gactgaggaa
    36601 caaatccgca atgatttgat tgccgccgtc aaaggcgagg cttctggact gttcaccaac
    36661 aatcccgtat tggacattaa aacttttcgt ttcacgctgc cgtcaggaaa aatcgatgtg
    36721 ggcggaaaaa tcatgtttaa agatttgaag aaggaagatt tgaaccaatt gggtttgatg
    36781 ctgaagaaaa ccgaggcaga catcagaatg agtattcctc aaaaaatgtt ggaagatttg
    36841 gcggtaagtc aggctggaaa tattttcagc gtcaatgccg aagatgaggc ggaaggcagg
    36901 gcaagtcttg acgacatcaa cgagaccttg cgcctgatgg tggacagtac ggttcaaagt
    36961 atggcaaggg aaaaatatct tactttagac ggtaatcaga ttgatactgc catttctctg
    37021 aaaaacaatc agttgaaatt gaacggtaaa acgttgcaaa acgaaccgga gccggatttt
    37081 gatgaaggcg gtatggtttc agagccgcag cagtaatggg tcaaatgccg tctgaaatgt
    37141 tcaggcggca ttttgttgta ttggaaactg ccgttttcaa ccattccttt agataagccg
    37201 tgtcggattc gtttttatag tggattaaat ttaaaccagt acggcgttgc ctcgccttag
    37261 ctcaaagaga acgattctct aaggtgctga agcaccaagt gagtcggttc cgtactattt
    37321 gtactgtctg cggcttcgtc gccttgtcct gatttttgtt aatccactat aggtcggaga
    37381 agatatttta atccgctgta aaatagaaaa tgccgtctga acatttcaga cggcatttgc
    37441 tcaaataaac cttatcggct gtttattcag tcggatttat tttttctttt gcggaggcag
    37501 gtcggtacaa gtacccaatg ccacttccgc cgccataccg atggattcgc ccaaggtcgg
    37561 gtgcgggtgg atggttttgc cgatgtctgc cgcgtcgcag cccatttcga tggcaaggca
    37621 gacttcgccg atcatgtcgc caccgttcgg accgacaatg ccgccgccga tgatgcggcc
    37681 ggtttcggca tcaaaaatca gcttggtaaa gccgttgtcg caaccgttgg caatcgcacg
    37741 gccggaagcc gcccacggga agttggcttt ggtgattttg cggccggatg ctttggcgga
    37801 caactcggtt tcgcccaccc acgccacttc gggggaagtg taggcaacgc ccggaatcac
    37861 gcgcgcgtcg aagtaggctt tgtggccggc gcagttttca gcagcaacgt ggccttcgtg
    37921 aacggctttg tgtgccaaca ttggttgacc gacgatgtcg ccgatggcgt agatgtgcgg
    37981 cacattggta cgcatttgtt tgtccacttc gatgaagccg cgatcggtaa cggcaacgcc
    38041 tgctttttcc gcgctgatga gtttgccgtt gggcgcgcgg ccggcggcaa ccaatacggc
    38101 atcgtaacgt tgcggctctt taggcgcatt tgcaccttca aaggtaacgt aaacgccgtc
    38161 ttctttcggc tcgactgcaa cggttttggt gttgaccata atgttgtcaa aacggtattc
    38221 gttttgtttt tgccatactt tcaccaagtc gcggtctgcg ccttgcatca ggccgtccat
    38281 catttcaacc acatccaaac gcgaacccag cgtgctgtaa accgtaccca tctcgaggcc
    38341 gataatgccg ccgccgataa tcagcagttt gcccggtact tctttcagag ccaatgcgcc
    38401 gctggaatcg atgatgcgcg gatcttcagg aatgaaaggc agtttggtta cgcggctgcc
    38461 tgctgcaatg atacagtttt tgaaggcaac gatttttttc tcgccggtag tggctgcctg
    38521 ttcgtacgcg tcgccggcag tcagcgacac ttccaagtgg tgcgggtcta agaattgccc
    38581 gtcgccttgg ataacgtcca ctttacggct tttcgccata cctgccaaac cgcccgtgag
    38641 gcgggaaact acgccgtctt tgtaggcgcg aagcatatcg atgtcgagtt ccggctcggg
    38701 gtatttgata ccgttggcag ccaagtggcg cacttcgtcg ataacggcgg cattgtgcaa
    38761 caaggctttg gaagggatac agccgacgtt caggcaaacg ccgcccaaag ttttgtaacg
    38821 ttcgacgatg gcgactttca agccttcatc ggcagcggca aatgcagcgg agtaaccgcc
    38881 gggaccgcca cccaatacga ccacgtcgta ctcggcatcg gcagaaccgc cgaattgcgc
    38941 ggcttgcgga gcaggagcag cagctttagg ggcttcttgc gccggggcgg cagcaggtgc
    39001 ttcagctttg ggagcggctg ccgtgccttc agcttcaacg acgacaatca agccgccttc
    39061 ggagattttg tcgccgactt tgactttcac ttctttgacc acgcccgcaa cttcggcagg
    39121 cacgtccatc gtcgctttgt cggtttccag ggtaatcagg gtatcgtcaa cggcgatggt
    39181 gtctcctacg ttcacttcaa ctgcgataat atctacattt tcgtgtccgc caatgtcggg
    39241 cactttcaat tcaactaagc tcatgtctca tctttctgaa tgatgttcaa acttcctttt
    39301 cagacggcac aggccgctat gccgtctgaa gccgatcggg ttacagggta atgcggcgga
    39361 agtctttcaa cagcttcgcc aagaatacgg taaagcgcat accggccgca ccgtcgatga
    39421 cgcggtggtc gaaagacagg ctcaacgggc acatcaggcg tggggcaaat tctttgccgt
    39481 tccaaaccgg tttgatttgg gatttgcaca cgcccaagat ggcgacttcg ggagcgttca
    39541 caatcggcgt gaaacctgtg ccgccgatac cgcccaagct ggaaatggta aagcacgcgc
    39601 cttgcatttc ttgcggtttg agcttgcctt cgcgggcttt tttagacaat tcggtcagct
    39661 cttggctgat ttgtttcaag cctttttgat ccacgtcttt gatgacggga acaaccaagc
    39721 cgttcggcgt atcggctgcg aaaccgatgt tgaagtagtt tttcagcacc aggttgtcgc
    39781 cgtccagaga agcgttgaat tcggggaagg ctttcagcgc ggaaacggag gctttgatga
    39841 tgaacgctag aggagacagt ttcacgcctt cgcgttccca ttctttgttc agttgtttgc
    39901 ggaattcttc cagctcggtc atatctgctt cttcgtgtac ggtaacgtgg ggaatcacca
    39961 cccagttgcg agacaggttt tgaccggaga ttttcttaat gcgggacaat tctttaactt
    40021 cgacattgcc gaatttggag aagtccactt taggccacgg cagcaagtcc agaccgctgc
    40081 ccaaagatgc gccggctgcg gcaggttttg ccgcgccacc ctgcattacg gatttcacaa
    40141 aggctttgat gtcgtcgccc acgatgcggc ctttcaagcc ggtacctttg acttggccca
    40201 aatccacgcc caattcgcgc gccagtttgc gtgcggaagg accggcgtgt gctttggcga
    40261 aagcggcctc gtcgattttg gcagcggcag gtgcagaagg tgcaggcgcg gcggcgggtg
    40321 cggcggcagc agtcggaggc ggagcggcag ccggtgcggc agcttgagcg gcttgagcag
    40381 gggctgctgc ggcagagccg acggtttcta cttcgataat ggcagagcct tcggacactt
    40441 tgtcgccgac ttttaagaat acggctttaa cgacaccggc agcggtacaa ggtacgtcca
    40501 ttgtcgcttt atcggtttcc aaagtaatca gcgtgtcgtc ttcggcaacg gtgtcgccca
    40561 ctttgatttc aacggcgatt acatccacat cggtatggcc gccgatatcg ggaacggcta
    40621 cttgaacggt tgcaccgcct gcggcaacgg gtgcggcagc agccgaggcg gcttcggcag
    40681 cggcggcacc ggtttcaacg gtcaaaatta cgccgccttc ggagattttg tcgccgactt
    40741 tgacttttac ttctttcacg acaccggcag catcggcagg cacatccatc gtggctttgt
    40801 cggtttccag tgtaatcagg gtgtcgtcaa cggcgatggt gtcgcccgct ttaacttcta
    40861 cggcgatgat gtcgacgttt tcgtgaccgc cgatatcggg gactttgatt tctacgatac
    40921 tcatttgagt tcctttaatc ttgttcagtt ggatgccgtc tgaaagctgc ttcaggcggc
    40981 atcggtacgg tttgtctgct caaaccattc gggcattcgg ttttcagacg gcctgatgtc
    41041 ggaatggggc aaacagaccg tctgaaacat caatcagcgt ttccagctag gagctgaatc
    41101 ggctttgatg ccgtatttct caatggcttg ttgaacggtt tctttgctga ctttgccttg
    41161 ttccgccaat gcgctcaatg ctgccacggc aacgttgtag cgatccactt caaagaagcg
    41221 gcgcaggttg gcgcggctgt cggagcggcc gaagccgtca gtacccaaga cgtggtagtc
    41281 gttcgggatg taggcgcgga tacggtcagc atagctgcgg atatagtcgg tagcggcaat
    41341 aaccggaccg tcatgacctt gcaatttgga agtaacgaaa ggtacttttt cggcttccag
    41401 cggatgcagg cggttgaagc gttctacctc gacagcgtcg cggtgcagca ggttgaagga
    41461 tgggcaagac caaatgtctg cttccacgcc gaagtcggct ttcagcagct cggcaccggt
    41521 aaccacttct tgcaaaatcg taccggaacc catcagttgg actttcttgt cgcctttgcc
    41581 gccggctttc agcaggtaca tacctttcaa gatgtcttgt tccgcacctt cgggcatatc
    41641 cggatgggtg tagttctcgt tcatcagggt gatgtagtag aacacgtctt cattattggc
    41701 atacatacgg cgcagaccgt cttgtacgat gacggcgact tcgtattgga aagtcgggtc
    41761 ataagatacg cagttcggaa tcaggtcggc ctggatgtgg ctgtggccgt cttcgtgttg
    41821 caggccttcg ccgttcagcg tcgtacggcc ggcagtaccg cccagcagga agccgcgcgc
    41881 gtgcatatcg cccgccgccc aagccaagtc gccgatacgt tggaaaccga acatagaata
    41941 gtaaatgtag aacggaatca tcgcgaagtc gctgttggcg tagctggttg cagccgcaat
    42001 ccagtcggcc atcgcgcccg gttcgttaat accttcttgc aagatttgac cgtcaacgga
    42061 ttctttatag aacatcagtt ggtctttgtc ttgaggggta tattgctgac ctttcggatt
    42121 ccaaataccg tattggcgga acataccttc catgccgaaa gtacggcttt cgtcgggaac
    42181 gataggtacg acgcgtttgc cgattttttt gtctttcagc aaagtggaca ggatgcggac
    42241 gaatgccatc gtggtcgaga actcgcgttc accgctggat ttgagttgtg cgtcgaatgc
    42301 tgacagctcg ggcacttcca atacttcctg cgtcggtttg cgttgcggca ggtagccgcc
    42361 caaagcatcg cggcgtgcgt gcaggtattt gtattcttcc gtatcggggg caaaagtcag
    42421 gtaaggcaga tcgccgcttt cgatttgttc gtcggtaacc ggaatgtcaa agcggtcgcg
    42481 gaattgtttc agggacgctt tgtccatttt tttggcttgg tgggcaacgt tctgaccttc
    42541 gccggatgcg cccataccgt aacctttaat ggttttcgcc aagatgacgg taggtttgcc
    42601 gtcggcatgg ttcgctgcgc ggtcgtaggc gttgtacact ttttgcgggt cgtggccgcc
    42661 gcggttcaat gcccagagtt gctcatcggt catatcggca accaatgctt tcagttcggg
    42721 cgtattgaag aagtgttcgc gcacatacgc gccgtctttg gatttgtaag tttggtagtc
    42781 gccgtccaaa cattcttcca tacgttggcg caggataccg tctttgtctt tcgccaagag
    42841 gcggtcccag cggcggcccc aaatgacttt gacgacattc cagccggcgc cggcaaagtt
    42901 gccttccaat tcttggatga ttttgccgtt gccgcgtacc ggaccgtcca agcgttgcag
    42961 attgcagttg atgacgaaaa tcaggttgtc caagccttcg cgtgcagcca gtgcgattgc
    43021 accttgagat tcgggttcgt ccatttcgcc gtcgccgcag aaacaccata ctttacggcc
    43081 tttggttttt gccaaaccac gcgattccaa gtatttcagg aaacgcgcct gataaatcgc
    43141 catgatgggc cccaagccca tggatacggt cgggaactgc caaaagtcgg gcaagaggtg
    43201 ggggtgcgga taggaaggca gaccgtgtcc gtccacttct tggcggaagt tgttcagctg
    43261 gtcttcggtc agacggccct cgacgaatgc gcgtgcatag atgcccgggg cgacgtgacc
    43321 ttggaagaag accaaatcgc cttcttcgcc ttcgcctttg gctttccaaa agtggttgaa
    43381 accgacttcg tacatggtgg cggcagattg gaaagatgcg atgtgcccac ccagttccaa
    43441 atctttcttg ccggcgcgca atacgatggc ggcggcgttc cagcgcacga atgcgcggat
    43501 gcggtgttcg atgttttggt cgcccggaat gcctttttcg ttttcaaccg aaacggtatt
    43561 caaatacggt gtggtcgtgc cgtgtggcat acgtacgccc ttgtcgcggc agtatttgac
    43621 caggttttcc aagaggtatt gcgcgcgttc gccgccttca tattcgagga cggagcttaa
    43681 cgcgtccagc cactcttggg tttcgatagg gtcaacatcg tgtaattggg tggacatagt
    43741 atctatcctt tatgttgagt gtttaatcgg cagggagggt gtagccaacc cctttatttt
    43801 cgtttgtgaa aaataataag caaaaacgaa aatttctaaa tcaaaccgaa aaaaataatt
    43861 taagtttaat gttttcaaaa aattataaaa gttttggaaa caagggaaaa cttgaaaaaa
    43921 atgttcgatc tgctccacac gaaatcctat cagcaatcgg gtctgctggc aaataaccat
    43981 gcctgtaaaa gcaggtttta tactgaagtt ggcgtttggt aaggtcaagt ctttttgatt
    44041 tcgaaatatt ctgtttgatt ttggcgatat tttttcggaa ttgtggtata tcgaatcatt
    44101 atgtctctgt cggcaatttt cctattgtag aaaatctata cacaagcttt gtggataacc
    44161 gtgttgataa gccacggctt gtgttaaaaa agtcttacgc aacaaatgta cgcttatttt
    44221 gattaaaaaa taggcacatt taaatctata aaaatcatgt gcttatgttc aatatgatgt
    44281 ttctggtcat gtttttgccg tctgttatgg gatttctccc gcgcttgggg cagggggtga
    44341 attttggagg ttggtgcaaa acctgctttt ttcgcgttac aatctgcacc cgatttactt
    44401 ttgaatttgc ctgtttggaa aaatactttt atgaaagcca gccaattctt tatctctact
    44461 ttaaaagaag cccctgccga agccgcgctt gccagccaca agctgatgat tcgcgccggt
    44521 ctgattaaag ccaacgcgtc cggcctttat acttggatgc cgatggggct gcgcgtgtta
    44581 cgcaaagtcg aaaacgtcgt gcgcgaggaa atggcgcgcg cgggcagcgt ggagctgctg
    44641 atgccggtgg tgcagcctgc cgagctgtgg caggaatccg gccgctggga attttacggt
    44701 aaagaactgc tgcgcctgaa agaccgccac gaccgcgatt tctgcatggg cccgacctgc
    44761 gaggaagtca tcgccgacat cgtgcgcaaa gaaatcaaca gctacaaaca gctgccgaaa
    44821 aacttttacc acatccaaac caaattccgc gacgaagtgc gcccgcgttt cggcgtgatg
    44881 cgcgcgcgcg agttcgtcat gaaagacgct tattccttcc atgccgacta cgcctcgctt
    44941 cagacgacct atgatgccat gtatgactct tactgccgca tcttcacccg tctgggcttg
    45001 gcattccgcc ccgtcgccgc agacaccggc agcatcggcg gtacgggttc gcacgagttt
    45061 caagtgttgg cggaaagcgg cgaagatgtt attgcgtaca gcgacacttc cgattacgcc
    45121 gccaatatcg agttggcacc gaccttgccg cttaaaggcg aacgcgccgc tgctcaggct
    45181 gtgttgacca aagtacatac accaaacgtc aaaaccattg agtctttggt tgaattcctg
    45241 aatattccgg ttgaacaaac cctcaaatcc atcgtggtcg aaggcgaaaa cgaaggcgaa
    45301 atcgtcttat tactgttgcg cggcgaccat gagttcaacg acatcaaggc agaaaaactc
    45361 gcaggcgtga gatcgccatt gacgatggca agtcctgccg cgattgtcga acagttcggc
    45421 gcaaacggcg gctcgctggg tccggtcggc tttgcaggta aagtttatgc cgatttcgcc
    45481 actgaaaaag gcgcggactg ggtcatcggt gcgaacgaag acggctacca ctataccggc
    45541 ttcaacttcg ggcgcgatgc cgccgagcct gaattcgtcg atttgcgtaa tgtggtcgaa
    45601 ggcgacgaaa gccccgacgg gcaaggccgt ctgaaactgg cgcgcggcat tgaagtcgga
    45661 cacgtcttcc agttgcgcga caaatacacc caagccatga acgtaagctt ccttgacaac
    45721 aacggcaaat cgcaaattat ggaaatgggc tgctacggca tcggcatcac ccgcgtcgtt
    45781 gccgccgcca tcgagcagaa taacgacgaa aaaggcatca tctggaccaa agcaatggcg
    45841 ccgtttgaag tcgttatcgt gccgatgaac tacaaaaaat cagacaccgt acgcgaagcc
    45901 gccgacaaaa tctatgccga attgctggcg gcaggcgcgg atgtgctgct ggatgaccgc
    45961 gacgaacgcg caggcgtatt gctgaacgat tccgagctgt tgggtattcc gcaccgcatc
    46021 gtcatcggcg accgcgcttt gaaagaaggc aatgtcgaat acgccgaacg ccgcaacaac
    46081 gaagcgcagg cagttgcaat cggagaaatt gttgcgcgtg taacagcttt attaaatggg
    46141 taagcttggt caaatgccgt ctgaaaataa tttcagacgg catttttatt tggggagaaa
    46201 gtgaagtggc ttcagtattt ttagaaggag aagcagtcga ggtcggcaat attttctgta
    46261 tcggcaggaa ctatgccgca catattgaag agttaaaaaa cgaaatacct tccgaacctg
    46321 tggtgtttat gaagccgtca ggcagcattt tgaacagcgg cggtacaatc ttgctgcccg
    46381 agtttagtag ggatgtgcag tttgagtgcg aactcgtgct gctggtcggt aaggattcag
    46441 acggcacggg cgagggtaaa gatattttgg gatgtgtcgc aggatatggt gtagggctgg
    46501 accttacggc acgggatatc caatgccgtc tgaaggaaaa agggctgccc tggctgaagg
    46561 caaaagggtt caggcattcc gcgtgcgtgt cggattttgc ggcggcaggc agaatcggca
    46621 atcccgagaa tgtgttgttt tcattaaaac aaaacggcgt attgaaacag cgcggggata
    46681 ccggtttgat gatttacccg attcgggaaa ttttacacaa actggcggca gattacggtt
    46741 tggggaaagg ggatttggtg tttaccggaa cgccctccgg cgtgggcgca atcggtgcgg
    46801 gggacaattt ggcattggag ctggacggct tggtgcgcgc ctctttcacg gtagggtgtt
    46861 aaccgcgccg cttaaccctc acgcccgttg aaacattccg ccggaccgcc ctcgaaaaaa
    46921 ccgtgcaaga tggcttgcgc cgccacttgg tcgagcaccg atttgcgttt tttgccgaag
    46981 acctgtgctt ccgaaagcag gctttcggca tagacggacg acagccgttc gtcaacccaa
    47041 tagacgggga gattgaacct gccgttcagc ctgcgtccga acttgcgcga caggtgcgtc
    47101 atttcatgtt tcgtgccgtc ggtatgcacg ggcagtccga cgacaaaata acgcggctgc
    47161 cattcttgaa ccagcttggc gattgccgcg aacttttcat cgttgctgcc gccggtaacg
    47221 gtgctcaaag gatgggatag ccctaattcc gcgtctcctt gtgccacgcc gatacgcgct
    47281 tcgccgaagt cgaatgccag tgccgttcct tttggaattt tatgcatggc cggctcccga
    47341 aaacagggcg agcgggtcga tgccgagttt ggcgaatgcg gcggcgtaac ggtgttcgta
    47401 ggggatgtcg aacaggatgt gttcgtcggc gggaacagtc agccacgcat tgtcggcaag
    47461 ttcgcgttcg agctggcctt ttccccagct tgaatagcct atgctgatca aggctttgtc
    47521 aaccgcacct tcgcgtgaaa tattttcaat cacgtctcgg gaagaagtta gcgcgatatt
    47581 gtctgaaacg ccgatactgc tttgccagtt gccgatcggg gtatgcacga cataacctcg
    47641 ctcgacttgc accggcccgc ccatcatcac gctgtcgtgc tgcatccgca tggggatgtt
    47701 tttgccggtg gcggaaaaaa tcatgtccat cgtaatcgga gagggtttgt tgatggcgat
    47761 gccgagtgcg ccgtcttcat cgtgtttgca gatatagacg accgattgtg aaaaaaacgc
    47821 gtcttccata tcgggcatgg cgacgagaaa gtggttggag aggttcatat cagcgtttgt
    47881 cgggattttc tatcgggttg gaaatcatgc aggcgccggc aagcaggttg ccggaagtat
    47941 cggcttgcac cccatcggtt tgcggtatgc cgccgccgaa acaggaaacc gcgcttaagg
    48001 aatttttcgg cgagccttgg atgattttat cgctgtacac caaataggcg aaggttttgc
    48061 gtttggggtc gtaataacgg acaatctgcc ggctcttgaa cgcgaagctc gcaccgtgtt
    48121 tgaaaacttc tttcggtttg cgcacggcgg tttcgtcaaa agaaatcgaa gatgccgtct
    48181 gaacgcacga aaccgatgcg tcggacgcgt cctcttccaa attgaccatt tccttcaagc
    48241 cgcctttttt tgcatacgaa atataacagg caaccccttg aacgtcggga tcgtcgaatc
    48301 cttccacttc gatacggtcg tttttgccca gtatgttgaa aacggtactt gcccgtccga
    48361 ttttatcggt ttcgccgctg ccgcaggcag tcagcaggac ggcggcagac agcagtagca
    48421 gtctgttcat caaaatttcc ttatcggttg aatccccgtt ttccgtgaag gcggcagggc
    48481 ttgctttgtt tggaggggcg cacgttccca aaatcgggca acatacggta tgcggcttaa
    48541 tgtgctaccc tgtgtgtcgg aacacaatat ccgttgcggc attgaaaata tgacgcacaa
    48601 tataaggctg tttgagccga ttgcaagtat ccgcgcaaag aaggcgcaag attgggcaaa
    48661 cggcattttc agacggcata actgacagta taatccaaac gtccggctgc tttcgtgcag
    48721 ccttcagtat tatccaactt tttccgaagg tcgaaccatg cgctacaaac cccttctgct
    48781 tgccctgatg ctcgtttttt ccacgcccgc cgttgccgcc cacgacgcgg cacacaaccg
    48841 ttccgccgaa gtgaaaaaac agacgaagaa caaaaaagaa cagcccgaag cggcggaagg
    48901 caaaaaagaa aaaggcaaaa atggcgcagt gaaagataaa aaaacaggcg gcaaagaggc
    48961 ggcaaaagag ggcaaagagt ccaaaaaaac cgccaaaaac cgcaaagaag cagagaagga
    49021 ggcgacatcc aggcagtctg cgcgcaaagg acgcgaaggg gataagaaat cgaaggcgga
    49081 acacaaaaag gcacatggca agtccgtgtc cggatccaaa gaaaaaaacg caaaaacaca
    49141 gcctgaaaac aaacaaggca aaaaagaggc aaaaggacag ggcaatccgc gcaagggcgg
    49201 caaggcggaa aaagacactg tttctgcaaa taaaaaagtc cgttccgaca agaacggcaa
    49261 agcagtgaaa caggacaaaa aatacaggga agagaaaaat gccaaaaccg attccgacga
    49321 attgaaagcc gccgttgccg ctgccaccaa tgatgtcgaa aacaaaaaag ccctgctcaa
    49381 acaaagcgaa ggaatgctgc ttcatgtcag caattccctc aaacagcttc aggaagagcg
    49441 tatccgccaa gagcgtatcc gtcaggcgcg cggcaacctt gcttccgtca accgcaaaca
    49501 gcgcgaggct tgggacaagt tccaaaaact caataccgag ctgaaccgtt tgaaaacgga
    49561 agtcgccgct acgaaagcgc agatttcccg tttcgtatcg gggaactata aaaacagcca
    49621 gccgaatgcg gttgccctgt tcctgaaaaa cgccgaaccg ggtcagaaaa accgcttttt
    49681 gcgttatacg cgttatgtaa acgcctccaa tcgggaagtt gtcaaggatt tggaaaaaca
    49741 gcagaaggct ttggcggtac aagagcagaa aatcaacaat gagcttgccc gtttgaagaa
    49801 aattcaggca aacgtgcaat ctctgctgaa aaaacagggt gtaaccgatg cggcggaaca
    49861 gacggaaagc cgcagacaga atgccaaaat cgccaaagat gcccgaaaac tgctggaaca
    49921 gaaagggaac gagcagcagc tgaacaagct cttgagcaat ttggagaaga aaaaggccga
    49981 acaccgcatt caggatgcgg aagcaaaaag aaaattggct gaagccagac tggcggcagc
    50041 cgaaaaagcc agaaaagaag cggcgcagca gaaggctgaa gcacgacgtg cggaaatgtc
    50101 caacctgacc gccgaagaca ggaacatcca agcgccttcg gttatgggta tcggcagtgc
    50161 cgacggtttc agccgcatgc aaggacgttt gaaaaaaccg gttgacggtg tgccgaccgg
    50221 acttttcggg cagaaccgga gcggcggcga tgtttggaaa ggcgtgttct attccactgc
    50281 accggcaacg gttgaaagca ttgcgccggg aacggtaagc tatgcggacg agttggacgg
    50341 ctacggcaaa gtggtcgtgg tcgatcacgg cgagaactac atcagcatct atgccggttt
    50401 gagcgaaatt tccgtcggca agggttatat ggtcgcggca ggaagcaaaa tcggctcgag
    50461 cgggtcgctg ccggacgggg aagaggggct ttacctgcaa atacgttatc aaggtcaggt
    50521 attgaaccct tcgagctgga tacgttgatc ggattgccga aacggtaggc tttatgcaaa
    50581 tcgtgccgat atggtgcgct gttccgtgaa gtttgccgtt tgccgtacct gtattttccg
    50641 gtttttggaa atcaagagag aaagttaaag aagaatgtcg aaacctgttt ttaagaaaat
    50701 cgcactttat actttgggtg caatcagcgg cgtggccgtc agtctggcgg tgcagggttt
    50761 tgccgccgag aaggacaggc gggataacga agtcctgccg gtgcaatcca tccgcacaat
    50821 ggcggaggtt tacggtcaaa tcaaggcaaa ctactatcag gacaaacccg atgccgattt
    50881 gtttgaaggt gcgatgaagg gtatggtggc cggtttggat ccgcattccg aatatatgga
    50941 taaaaaaggt tatgccgaga taaaggagtc caccagcggc gaatttggcg gcttggggat
    51001 ggaaatcggg caggaagacg gatttgtcaa agtggtttcg ccgattgagg acacgcctgc
    51061 ggaacgggcg ggggtgaaaa gcggcgattt cattgtgaaa atcgataatg tttcgacacg
    51121 cggcatgacg gtcagcgaag cggtgaagaa aatgcggggc aagccgggta cgaagattac
    51181 tttgacgctg tcgcgcaaaa atgccgacaa gccgatagtc gtcaacctga cccgtgccat
    51241 tattaaagtg aaaagcgtcc gccatcacct gatcgaaccc gattacggct atatccgcgt
    51301 gtcgcagttc caagagcgga cggtcgaaag cgtcaatacc gccgcaaaag agctggtaaa
    51361 ggaaaataaa ggaaaaccgc tcaaggggct ggtgttggat ttgcgcgacg accccggcgg
    51421 gcttttgact ggcgcggtcg gcgtgtcggc ggcatttctg ccgtctgaag cagtcgtcgt
    51481 cagcaccaag ggacgcgacg gcaaagaccg catggtactg aaagccattc ctgaagatta
    51541 tgtgtacggg atgggcggcg attcgttggc gggcattcct gccgagttga aaaccatacc
    51601 gatgacggtt ctgattaatt cgggttcggc ttccgcgtcg gagattgtcg caggtgcatt
    51661 gcaggatcat aaacgcgcgg tcatcgtcgg tacgcagagc ttcggcaaag gttcggttca
    51721 gactttgatt cctttgtcca acggcagcgc ggtcaagctg acaacggcac tgtattatac
    51781 gccgaacgac cgttctattc aggcgcaggg gattgttccc gatgtcgaag taaaagataa
    51841 ggaacgcatt tttgaaagcc gcgaggcgga tttggtcgga cacatcggca atcctttggg
    51901 cggcgaggat gtgaacagtg aaacccttgc cgtgccgctt gaaaaagatg cggataagcc
    51961 cgctgtaaaa gaaaaaggta aaaagaaaaa ggacgaggat ttgtcttcaa ggcggattcc
    52021 caaccctgcc aaagacgacc agttgcggaa agctttggat ttagtcaagt cgcccgagca
    52081 gtggcagaag tctttggggc tggcggcgaa aaagccggtt tcaaataaag ataagaaaga
    52141 taaaaaagat aagaagtagg ttttgacgat gccgtctgaa aggatttcag acggcatatt
    52201 atgtttgaaa ggacaggtta tgagcgattt tttaccggaa tttgaaccgt gcggcattta
    52261 tagtggatta acaaaaatca ggacaaggcg acgaagccgc agacagtaca aatagtacgg
    52321 caaggcgagg caacgccgta ctggtttttg ttaatccact atacttgggt agcgattggg
    52381 tttcagacgg catacattca ggatttcacc gccttatgcc gtctgaaaga cgtttccgac
    52441 ccatccctac tacacacttt gtccgcaaac gcatcacagg caagattatg gaagttatcc
    52501 aatacccaaa ttcccccttc aaactccacc aacccttccc gcccgcaggc gaccagccca
    52561 ccgccattgc aggcctgctc gaagggcttt cagacggcct tgcctatcaa accctgctcg
    52621 gcgtaaccgg ttcgggcaaa acctacacca tggcgaacgt catcgcccaa agcggccgcc
    52681 ccgccatcat catggcgcac aacaaaaccc ttgccgccca gctttacgcc gaaatgcgcg
    52741 aatttttccc cgaaaacgca gtggaatatt tcgtctccta ctacgactat taccagcccg
    52801 aagcctatgt gcccagccgc gacttgttca tcgaaaaaga cagcgcgatc aatgaacaca
    52861 tcgaacaaat gcgcctttcc gccaccaaaa acctgatgac gcgcgacgac gtgattatcg
    52921 tcgccaccgt gtccgccatt tacggtatcg gcgacccgac cgagtatcaa caaatggtgt
    52981 tgtccgtcaa agaaggcgat accatagccc agcgcgacat catcgccacg ctcgtttcca
    53041 tgcagtacga acgcggcgat ttggacttca aacgcggcag cttccgcgtg cgcggcgacg
    53101 tgattgacgt gtaccccgcc gaaagctccg aaaacgcctt gcgtatcagc ctgttcgacg
    53161 acgaaatcga ccgcctcgat atgttcgacc cgctttcagg cagccttatt caacgcgtcg
    53221 gccgctacac cgtcttcccg tccagccact acgttacccc gcgcgacacc gtattgcgcg
    53281 cctgcgagtc catcaaagaa gaattgcgcg aacgcatcga atttttcgcc cgcgaacaac
    53341 gccccgtcga gcaacaacgc atcgaacaac gcacccgctt cgacctcgaa atgctctacg
    53401 aaatgggctt ctgcaaaggc atcgaaaatt attcccgcca cttctccggc aaaaaagaag
    53461 gcgaaccgcc gcccacgctg atggactatc tgcccgacaa cgccatcatg ttcatcgacg
    53521 aaagccacgt taccgttacc caaatcggcg gcatgtacaa aggcgacgca tcgcgcaaac
    53581 aaaacctcgt cgactacggc ttccgcctgc cttccgcccg cgacaaccgc ccgctcaaat
    53641 tccacgaatt tgaaaaagtc atgccgcaaa ccgtcttcgt ttccgctact cccgccaaat
    53701 acgaagaaga acacgccgga caagtggtcg aacaagtcgt ccgccctaca gggctggtcg
    53761 acccccaaat catcatccgc cccgtcgcca cccaagtcga tgacttaatg agcgaaatca
    53821 acgaccgcat ccaaaaaggc gaacgcgttc tcgttaccac cctcaccaaa cgcatggcgg
    53881 agcaactcac cgactattac agcgaactcg gtatcaaagt gcgctacctg cacagcgaca
    53941 tcgacaccgt agagcgcgtt gaaattatta gagatttgcg gcttggactg tttgacgtac
    54001 ttgtcggcat caacctcttg cgcgaaggct tggacatccc cgaagtctcc cttgtcgcca
    54061 tcctcgacgc cgacaaagaa ggcttcctgc gctcgcaccg cagcctgatt caaaccatag
    54121 gccgcgccgc gcgcaacgtg aacggcgtcg cgattctgta cgccgacaaa atcaccgact
    54181 ctatgaaagc cgccatcgac gaaaccgaac gccgccgtga aaaacaaatt aaattcaacg
    54241 aagaacacgg catcgtgccg caacagatta aaaaacaggt caaagacatc attgacggcg
    54301 tgtaccacga agaagacggt ggtaaaggcc gtagacaagg caaaaacaag gttaaagtca
    54361 gcgaaattca caacgaagaa gacgcggtta aagaaatcgc caaactggaa aaagccatgc
    54421 agcaggcagc tagggatttg cagtttgagg aagcggcggt tatgcgtgat agaatacgga
    54481 atattaagga aagcctgttg tttggggcag agtaatgaaa tagtttaata ttctcagctt
    54541 aatgtataaa ggataatttt atgaaattgt caaaaacaag aatagataaa tctggcttag
    54601 cattggctaa acaacaatat aaagatgaaa ttgattttat tgaattggaa gaatgttttg
    54661 atttgtatag gcaatcacat ctttcaccat tatctaaaac aactattgat attcaaaata
    54721 ttcttaggga atatattggt gagtattata tagctcagcg actaaaaaga aaaccacaga
    54781 taatcagaaa gttaaatagg cttagcgtta gactaactca gttgcaagac attggtggtt
    54841 gtagaattat tgttccaaca aatagagatg ttgataagat atataagttt ttatcaagta
    54901 agaaggataa tcttgatttt ttaataaaaa aagtaaccga ttaccgtgaa aaaggtagag
    54961 atgattcagg gtatagagct ttacatataa ttatagaaag agaaaatctt aactttgaat
    55021 tacaaattag aagtaggata caacattatt gggcagaaag tatagagaaa acctctgttg
    55081 tttatggata ttacttaaaa gagcaagaag gggatagaga tgtaattaac tattttaaag
    55141 aattatcaga tgttttttat gaaattgaat cagggagaaa accaactact atacaaaagt
    55201 taaatcttga agatttaaga aaaagatgtg aagttattat tcagaaatca gatactcata
    55261 aaatattaaa tagctatgtt aatgaaggta taattagtgc gttgatagaa aaggaaaaga
    55321 gaaatactaa ttcattgaat aactggatac taatttttga ttggaatgca ggggttttcg
    55381 ttagttggga tgttgtagct caagatccga agcaagccgt tgaggtatat gttaattatg
    55441 agaatcagta tccatcttta gaggggttcg aggttgtttt gataggatca tccgatatcg
    55501 cttctgtaca aaaaacacat agtcattatt ttggcatagc ctcatatgaa aatattctag
    55561 aaacacttga tgaatcaatt ttttgctttg ctaaaaaaga tgatattgat attggggcaa
    55621 gaagaatatt ggcagcaatg gtaaggcata aattttgggg aacaaaaaca gtaacatcag
    55681 aaactttaaa aaatcatttc tgccaaaatc tttttggatt tgattattct ttaagggatt
    55741 taataagaaa agaattaata aaatatggaa gagataaaga tttatcattg aatatagcaa
    55801 agaaaatgga aatagaatcg tatttataag caagcgcagc ttgtatcccc atcaaccgtg
    55861 tgcgtggcta cgccacacac cttacctgcg tatggcacaa aaactttaaa accgaggtgt
    55921 agggtgtgtg cggtacgcac gcacgcgttc tttgtagtgc aaaccactgc ttcaaacttt
    55981 cagacgacct caaacgccgt ctgagaatct atggcataaa ggccgtctga aaaaatggtt
    56041 tcagtacaac tgccactggt tgtaacttga ttaaaaccac cctttcagac agcctgccgt
    56101 tttcagcaag cgtaggtcgg atactcgtat ccgacaaaac ctttaacatt cccgtcgttg
    56161 caatccgttg cagcaatgcc cgaaatgtcg gattcgagaa ttcgacctat acaatcattc
    56221 cgagtataat actatgaaat accgtcgttt ttaccgcaat ggcggcactt acttttttac
    56281 ggttgcaacc aataaacggc agaggatttt gaccgatgat gcggtgcgtt tggctttgcg
    56341 acaggcggta atggctgtgc gcgaacggta tccgtttgaa attttggcat gggtgttgat
    56401 gcccgaccat ctgcatacca tatggcggct gccggacaat gattctgctt attcggaacg
    56461 ctggcggcag atcaagcggc acagcaaata tttaatcggc ggcaatctca ggctttggca
    56521 aaaacgcttt tgggaacata ctatccgcga tgaggccgat tttgcctgcc attttgatta
    56581 tctgcatttc aatccggtca aacatggcta tgtaggacaa atttccgatt ggcggttttc
    56641 tacgtttcac cgttatgtca aacagggtat ttatccgcat aattggggtg gcggcaatgc
    56701 ggacttttct attgaatacg attaaagtaa tgtcggattc aagaatccga cctacggaaa
    56761 actaaagatt ttatacgggc tacggcttgc tggcttatgc gttggcttaa tttgaaaaac
    56821 agcacatcgg ttcataatac acaaggtatt agaacaaaag aagcagttga acagggattg
    56881 cgtggtaata atagacctga aaaaggaata ggtaatagat ggaattatga tggatttata
    56941 aaggaattag cgaagtaaca ggtattccaa atatttctga taaatataaa gaacaaggag
    57001 taaaaaaatg aaagtaatca ctattacatt gtttactagc tgcatactat ctggatgcta
    57061 tgggcttgaa tatggaatga gtggcggcat tcctcatgat gactgggcaa taggtagcca
    57121 tgttagtcaa gccaaagcag atgctgcgtg gaaagaatgt tctgacaaat atatgagaaa
    57181 tggtggttca ggattagtag aacaatgtat gaatgataaa ggattaatac gtttatctga
    57241 aatacgtcgt aggcaaaaga gagcagaaac acaaagagca gtaattaagt aacaataatg
    57301 aaatactact gttcccgaac aaagcggcat ttacgcaggt gatgacggct atattttgaa
    57361 aaatgccgtc tgtaagcaaa cgtgcttcag acggcatttt tttatccggc ggtctgttat
    57421 ccgatccgtt tgaataccaa gtcccaaacg ccgtgtccga ggcgtttgcc gcgcgcttcg
    57481 aatttggttt cggggcggta gtccggggtg ggggcgtagt ctgccgccgt attttgcagg
    57541 ctgtcgaagc tgctgaggac ttcaagcatc tgctgtgcat attcttccca gtctgtcgcc
    57601 aggtggatat agccgccggt tttgagtttg ggcagcagtt tggcgatgaa gggggcttgt
    57661 atcagacggc gtttgtggtg gcgttttttg tgccacgggt cggggaagaa tatgtggatg
    57721 ccgtcgagcg agccgtcttg cagcatattt tcgacaactt ctacggcgtc gtgccgcatc
    57781 acgcggatgt tttccaaatg gttttcttct atgagtttga gcaggttgcc tacgccggga
    57841 ccgtgtacgt cgatggcgag aaagtcggtt tcgggcagcc tgcgggcgat ttctgcggtt
    57901 gctgtcccca taccgaagcc tatttcgagg attttggggc ggttgcttcc gaaattggca
    57961 tcaagatcgg ccggtgttgc ttggtaatcg atgccgaagc tgtcccataa ggtatcgatg
    58021 gcgcgttgct gcgcggcggt catatggctt tggcggagga cgaaactgcg gatgctgcgg
    58081 ggatgtccgg cttgacggtc gtttggtgtt tggttttcgg cggtgtctgt cataatgctt
    58141 ccgtgcgctt gtgcaatcag gatgccgtct gaatgtgaaa ggcctgttcg gacggcggga
    58201 agggaaaggg gcgattatac ctgtttcgtt tcggcagggt aggtgtaacg ctgttcagac
    58261 ggcattttgc cattgttgca gcagttcttg caggacgctt ttttgcccgt atccgttgtt
    58321 tatggcttct tgcaggtagc ggcaggcttt ttctttgtcc ggcccgacac cgtgtccgct
    58381 gtaatggatg caggcgaggt tgtagaacgc catactgtct ttttttgcgg cggctttttc
    58441 aaaccatttg cgtgcttcat tgtagtcggc ggtcataccc tgtccgaagt aatacatgct
    58501 gcccagattg gtttgggctt tgctgtgtcc gagttctgcg gcttctgtgt agagtttgag
    58561 cgcggctgcg tattcgggcg cgcattgtaa tccgtaatgc agggcttggg ctttttgata
    58621 aagctgttct gccctttgcc gcctaatggc ggaatcttta atgccgccgt attggtcagg
    58681 atggtttaac gcgctgtcgg atatgagttt ctgataggcg gtaaggctgc cggcttcggc
    58741 tgcctgccgg taataatgcc gggctttttc cgtatcgggg gctatgccca aaccgtagcg
    58801 gcagatgtcg cccagtatcc gcaaaccttc gggatggcgt tcggcggcgg ctgcttcggc
    58861 gtgatgcagg gcaagtttgt agtttctttc cggatgcttg ccttgcaggt agatgtcggc
    58921 aagtgcggca tgggcatcgg ggtcattttc ctgtgcggcc tgttgaaacc ggtaaacggc
    58981 tttatcggga gccgtaggta ggatgagctc ggcaagcggg gtgtaggcgg gaatgtatcc
    59041 ttgttgtgcg gcggcgcgca aatgattgat agcttgggtc gtgtcggttg gtgtaccttg
    59101 tccgaaacgg tattgaaggc cgagctgcca ttgtgccgcc gccaagcctt gtgctgcagc
    59161 ctcgcggtag agcaggtgtg ccgtttcaaa atccggcggc gtgccgtacc ggcagtattg
    59221 ggcaagcagg tattgcccgt gggggttgtt gttttttgcg cttgtttttg cccatttcag
    59281 ggcttcttca aaatgtcggg acgcatacag caggtacatc aggcggactt gtgcttcagg
    59341 cagcccttcc tctgctaatg gtctgtaaag cgatatcagg gtttccgggg gtgcgccttc
    59401 caattcttgg atatatgcca gattgtaacg cgcgtaggga tgtccctgtt cggcggcgat
    59461 gcggagcatt tccatacctt gttcgcggtc ttggtagggg ctgtccgcgt ccatcaggtg
    59521 ttttgccaac tcgaatgcgg cggcgggatg acctgccgag gccgcttctg tcagcagtcg
    59581 gcggacttcg gtaaagttat attgtttttg agacaggcgt tctaaggcct gccgataggg
    59641 taagtcggga ttgttcatat cagatcgttt tccgttttgt cgaatcatcg ttattgtgtt
    59701 atgaagttag gtttatagtg gattaacaaa aatcaggaca aggcgacgaa gccgcagaca
    59761 gtacaaatag tacggaaccg attcacttgg tgcttgagca ccttagagaa tcgttctctt
    59821 tgagctaagg cgaggcaacg ccgtactggt ttaaatttaa tccactatat atcggtatac
    59881 cgacctgctg tatcatattt tttacagacg gattttgtct ttgacagcat gctaatgcag
    59941 atgattgtaa atcgtttccg ccaatgcctt gctgatgcct tccacttttt ccaagtcctc
    60001 gcggctggcg gcaatcacgc cgcgcagacc gccgaagcgg gtgagcaggg cttggcggcg
    60061 tttgctgcct acgccgggga tgtcgcttaa ggaggaggta acgcgggctt tgtcgcgttt
    60121 tttgcggtga ccggtaatgg cgaaacggtg cgattcatcg cgtacggttt gcaatagatg
    60181 caaggccggg ctgttgggcg gcaggcggaa gacttcgccg gtaaaaggca gtatgagctc
    60241 ctccataccg gctttgcgct ccgggccttt ggcaatgccg accaaaggga tgtgcagccc
    60301 gagttcttcc cataccgata cggctacgcc gatttgccct ttgccgccgt caatcaacac
    60361 ggcatccggc catttgacgg tctcgccgtt ggcttcggcc tcctgcattt tgccgtaacg
    60421 gcgcgtcaac acttcgcgca tggcggcgta gtcgtcgccg ggtttggcgg tcgtgatgtt
    60481 gtagcggcgg tattgcgaag gctggatgtt ttgctcatcg tacacaacgc aggacgcaat
    60541 agtggcttcg ccttgtgtgt ggctgatgtc gaaacattca aggcggttga ggccgtctga
    60601 atccatgccg aggatttttg ccagttcatc aatgcggtgt tgctggctgc tttgttgcag
    60661 gcggcgttgt gcaatcgcca tttgtgcgtt ttgttccgcc attttcaacc agactttgcg
    60721 ttcgcctatg gttttggtga caaattgcat ctgcttgccg tgttcgcctt ccaaagcctc
    60781 tttcagcgca tcgggaacgg aaaagttgct aataatgatg tcgggtttgc ttttgcccaa
    60841 ataatgttgg gcgacgaagg cttcggcgta atcttgtccg tttggctcgg gatcgttttt
    60901 ggtgtcgggg aaaaagcttt tatcgcctac atgccgtccg ccgcgtatgc tgacccagtg
    60961 tacgcagacg aggccgtctg aaacggcgag cgcgagcagg tcgatgtcgt tggggttgtt
    61021 cgggtttttg ctgtcgatga actggttgct ctgcataatg ccgagtgctt ggatttggtc
    61081 gcggtagcgg gcggcttctt caaattgcag attagcggcg gcggtttgca ttttgtgttg
    61141 cagggtacgc gtcagttcgt cggttttgcc attgaggaaa gttgctgctt cacgcacgct
    61201 gtcgtgataa tcttcttcgc tgatatgacc gacacaaggt gcggtacagc gtttgatttg
    61261 gtaaagcaga caaggacggt cgcggtgctc gaatacactg tcttcgcagg tacgcagcat
    61321 aaagactttt tgcaacactt gaatactgtc gcgcacggcg ttgctgttgg gatacgggcc
    61381 gaaatattga tttggctttt tcagtgtgcc gcggtaatac gccatttgcg gatattgatg
    61441 gccactgagc atcaaataag gatagctttt gtcatcgcgg aaaagaatat tgtatttcgg
    61501 cgacagagct ttaatgaagt tgttttcgag aatcagtgct tcggcttcgg aacgcgtgat
    61561 ggtggtttcg atatgatgca cctgttttac catcaatgcg atgcgcggcg aatggtcgtt
    61621 tttttggaaa tagccggaca cgcgccgctt gaggttgacc gctttgccga cgtataagac
    61681 tttgccgcct tcgtcaaaaa aacggtacac gcccggcagc ttgggcaggt ttttgaggaa
    61741 gagcgggatg tcgaattgtt ccggagaacg gttttctgta ttcatatcaa tcatttgaaa
    61801 aacggcttca gacggcatat cggcagcggc agccttatcc gttcggaaaa gctgtcgggt
    61861 ggttatatgc ggtcaatcga tttttacccg tttcaggcgc aaggcgttgc tcaacacgga
    61921 aaccgagctt gccgccattg ccgcgcctgc gatgacaggg tttaaaaaac cgagcgcggc
    61981 aagcggaatg cccaaaatat tgtagaagaa ggcgaaaaac aggttttgct tgatgtttct
    62041 caacgtcgcc cgcgataccg atagggcatc ggcgagttgg ttgaccgaat gttgcatcag
    62101 cgtggcggat gcggtgtgtt cggcaacgtc cgcgccgcct ttcatggcga agctaacgtt
    62161 ggcggcggcg agcgcaggtg cgtcgttgat gccgtctccg accatcgcca cggttttgcc
    62221 ggcggctttg agtttctgca cttcggcggc tttgtcgcgc ggactcatat taccgaaggc
    62281 gtgtgcgatg cccagttgtt tggcgacgta ttcgaccgtg ccttggttgt cgccgctcat
    62341 aatatagaca tcgatattgt gttttttcag acggcctatg gcttcggcgg tatcggcttt
    62401 caacgcgtcg gcaagtgcga atgtgccgat gggtttgtta tcgactgaga ccgcaacaat
    62461 gcttgcaata tcccaaacgc cgtctaaaaa cttcggcaag gccagttcgg caaattcggc
    62521 tttgcctgct ttcaccaaac ccacgccttc cacttcggcg gtaatgcctg cgccgacaac
    62581 ggtttgtgcg ttttgtgcgg cgggaatgtc caaaccgcgc gcttgggcgg cggagacgat
    62641 ggcacgggcg agcggatggg cggcgttttg ttcgacggcg gcggcgatgc ggtacaaagc
    62701 gtcttcgtca aagccgctgt cgggaacgca ataaacggcg gcaacctgcg ggctgccttc
    62761 ggtcagcgta ccggttttgt ccaacacgac ggcatcgacg tgggcggctt cctccattgc
    62821 tgccgcgtct ttaaaccaaa taccgtgttt aaccgctttg cccataccga ccataatcgc
    62881 ggcaggggtt gccagaccca gcgcgcacgg gcaggcaatc accaaaacgg cgacggtgtg
    62941 catcagcgca accgtccaat cgcccttaat cagccaagta acaataaaag tcaacaacgc
    63001 aatgcccacg acggcaggca cgaataccgc agccgcttta tcggctacgc gcgcaatcgg
    63061 tgctttactg ccttgtgctt cagagagcgc gttcatcatg tcgccgagct gggtttggct
    63121 gccgagctgc gtggcgcggt acaccacact gccttcggtc attaacgcgc ccgccaacac
    63181 tttgccgccc gccttttttt cttcaggatt ggattcgccg gtaagatggc tctcgtccgc
    63241 ccaaccgctg ccgctttcaa tgatgccgtc tgcggcaatg cgttcgccgt ggttggcgcg
    63301 gataaggtcg ccgatttgca cttggtcgat gggaagctgt ttccattcgc cgttgcgttg
    63361 cacgttgact tgggttggtg taagtttgag cagcaagccc aagctgttga ggctggattt
    63421 tttggtacgg tgttccaaaa atttacccag tgacacaaaa ccgatcacca tcacgcccac
    63481 ttcaaaatac acatgcgcca taccgtacgc cgcgtgcggg ctgaaaaaca gcatatagac
    63541 ggaatacagg taaatcgaga ccgtgccgat ggtaaccagc acgtccatat tcgccagtcc
    63601 gcccttaatg ctcgcccacg cgcttttgta aaacgggatt gccagccaaa gctgcaccac
    63661 gcttgccaat gcgaactgcc acaacggcgg aatcatccaa tcgtgtctgc cgatcatcat
    63721 ccccgccatg ccgataagga acgggacgtt gatggtgaac agcagccaca gccgccagcc
    63781 gatatggtgt tctgcttcgg gttgcggcaa tgtatcttcc gttttttcct tcgcgccgta
    63841 accggttttc tcaatgattt tggcaatgtc ggctactgag gttttgctgt cgtcaaacac
    63901 tacctgcgcc tcttcgctgg cgaagtttac ccccgccgat tcgacaaaat cttttttgtt
    63961 caacactttt tcaatgcgcg aagcgcaggc ctggcaggtc atgccttcga tttggaaacg
    64021 gattttttgt tgcataagcg tgattcctgc tttgatattc agacggcagt taaggctgcg
    64081 ggatgccgtc tgagcgccgg tatggtcgaa atttctcaaa cgcgccgata attcgagtag
    64141 aatccgaaaa cttgacacag caaaggaaaa acaatgtccc aacaccgcaa actgattatt
    64201 ttgggttccg gccccgccgg atacaccgcc gccgtctatg ccgcgcgtgc caatttaaac
    64261 cccgtcatta ttacaggtat cgcgcaaggc gggcaactga tgaccaccac cgaagtggac
    64321 aactggcctg ccgatgccga cggcgtgcaa gggccggaat tgatggcgcg gtttctcgcc
    64381 cacgccgaac gtttcggaac ggaaatcatt tttgaccaaa tcaacgccgt cgatctgcaa
    64441 aaacgcccgt ttacactcaa aggcgatatg ggcgagtaca cttgcgatgc cctgattgtc
    64501 gcaacaggcg cgtccgccaa atacctcggt ttgccgagtg aggaagcgtt tgcaggaaaa
    64561 ggcgtttccg cttgtgccac ctgcgacggt ttcttctaca aaaaccaaga tgttgccgta
    64621 gttggcggcg gcaatacggc agttgaagag gcactctacc ttgccaatat cgccaaaacc
    64681 gttaccctga tccaccgccg cagcgagttc cgtgccgaaa aaatcatgat cgacaaactg
    64741 atgaaacgcg tggaagaggg caaaatcatc ctcaagctgg aaagcaacct gcaagaagta
    64801 ctgggcgacg atcggggcgt aaacggcgca ttattaaaaa acaacgacgg ttctgagcaa
    64861 caaattgccg tcagcggcat ttttatcgcc atcgggcaca agccgaatac cgatattttc
    64921 aaaggtcagt tggaaatgga cgaagccggt tacctgaaaa ccaaaggcgg cacggcggac
    64981 aatgtcggcg caaccaatat cgaaggcgta tgggcggcgg gcgacgtaaa agaccatacc
    65041 taccgtcagg cgattaccag cgcggcttcc ggctgtcagg cggctttgga cgcggaacgc
    65101 tggctgggca gccaaaacat ttgaatgccg tctgaaaccg aaattttcgg cggaatgcaa
    65161 atttttcgca ccaaatcctt gattccgtcg gcaaacccca atataatgcc tgctctttga
    65221 accttgcttt ctgctttcgc atggcagaag gctgttttta ccatccataa ggagataaca
    65281 tgcgtcatta cgagatcgtg cttatcgttc atcctgatca aagcgagcaa gtgcctgcta
    65341 tggttgaacg ttacaaaacc atgattgccg aagcaaacgg taagattcac cgtttggaag
    65401 attggggtcg ccgccaactg gcttacccga ttaacaaaat ccataaagcc cattacgttt
    65461 tgatgaacat cgaaaccact cccgaagtgg ttgaagagct ggaaaccgca ttccgcttca
    65521 atgatgccgt attgcgccat ctaaccatca aaaccaaaca cgccgttacc gaagcatccc
    65581 ctatgttggg tggtgaaaag gctaagaacc tgttgagcgg tgcgtctgaa gaagcggtcg
    65641 cccaataatt gggattcaat aatcttgttt cgcttgccgc gttaattgaa aaggttttcc
    65701 ctattcgata tacgcctgcc ggaatccctg ttttagatat tattttaaag cacaaatcgt
    65761 ggcaggagga aaacgggcag caatgccttg tccaattgga aattccggca cggattttag
    65821 gcaggcaggc ggaagagtgg cagtatcggc aaggtgtata tgttcacgtc gaaggttttt
    65881 tagctcaaaa aagcagacgt tcccttatgc cgatgctcag gatacaaaat attcaagaat
    65941 ataaaggtta aacgacaatg gctcgtcaat cattcaaacg tagaaaattc tgccgtttca
    66001 cggctgaaaa aatccaagaa gtcgattaca aacaagttga tttgctgaaa gactttatct
    66061 ctgaaaacgg taaaatcatt cctgcacgca tcacaggaac gaaggcattc taccaacgcc
    66121 aattggctgt tgccgtaaaa cgcgcacgct tcctggctct gctgccttac accgaccaac
    66181 acaaataatt ttggagattg aatcatgcaa attattctgt tagaaaaaat cggcggtctg
    66241 ggcaacttgg gcgacatcgt aaccgttaaa aacggctacg cccgcaactt tctaattccc
    66301 gcaggtaagg caaaacgtgc gaccgaagcg aatatgaaag agtttgaagc acgccgtgcc
    66361 gaattggaag ccaaacaggc tgaaattttg gcagatgccc gagtccgtca ggaaaaattg
    66421 gacggtcaaa ccgttaccgt tgctcaaaaa gccggtgtgg acggccgcct gttcggttcc
    66481 gttaccaatg ccgacattgc tgctgcaatc gttgctgccg gcatcgaagc cgtgaaagca
    66541 aatgtacgtc tgccgaacgg tcctctgaaa gccgttggcg agtacgaagt ggaagtggct
    66601 ttgcacactg atgccgttgc taaaattacc gttgccgtcg ttgccgcaac cgagtaattg
    66661 aaattatcag atgccgtctg aaaccctgcc gattgtcgga atgtggtttc agacggtatt
    66721 tgttttgttt tccgtatatt ctgcaaaaat cgggatggtt gtttttatag tggattaaat
    66781 ttaaaccagt acagcgttgc ctcgccttgc cttgccgtgc tatctgtatt gtctgcggct
    66841 tcgtcgcctt gtcctgattt ttgttaatcc actatatttg cctgtggtct ttgcaggaat
    66901 agtttgttaa cgaaatttga tgcataaaat gcgccaaaaa atattggctg tgttttaata
    66961 tagtgttgat aagcgtacct ggcttcaata tactcaatag gatagatctc ttcctaaccg
    67021 aaaaaataat tgtcttttcc cttgcaaata attgaaatca acagattact aaaacacagc
    67081 caaaatattc aattgacaaa aacttttctg attttgagaa atctgtgaaa atcaggggat
    67141 tatttatttt gaaaatggta tcgggcataa aatttggctg tgtttcaata tggtgctgat
    67201 aacatacttt gtttcaaaat gttcaatagg ataacttcct gattgaccga aaaataatgg
    67261 ccttttccct tgcaagcagt tgaaatcaac agattgtcaa aatacatcct aaaaatttaa
    67321 taacttatat atatgattgc aaaggttgcg gcttgtatac cggtcattat ggcggaaata
    67381 ccgtttggga ggcagccgca tcgcgtggaa tcggcacggc aggcgatgcg ccgatgcctt
    67441 cgggcgtgaa ggcggggcaa tcggcagttt ggaaaaaggc aatggaatct gtgggcagaa
    67501 gaagttaagg gtaaaagtcg ggcgcacggt caggttgtct gtccttttgt cggaacagga
    67561 gactgggcag ctttgtcctg attaattgct tgtgcaaacg gtaaaaaggt tttttcgtgt
    67621 gttttaaagc aggttgtaca gcatttttcc ggcaatcaaa agcaacataa tgccgaagga
    67681 ttttttgagt ttggcagaag aaagtttgtg ggcggttttg acaccgagcg gggcaaaggc
    67741 aatggttgcc gcgctgagga cggcgacggc gggcaggtaa aggaagccca gtgacccttc
    67801 gggcaatcct gcaatattca ggccgttgag cagatacgat attgcgccgg agagtgcaat
    67861 cggccaggca aggccggatg atgtgccgat ggctttatgg gcggggaagc cgcagtggat
    67921 taagaagggg acggaaagtg aaccgccgcc tatgccgacc cagctcgaca ttgtgccgaa
    67981 cagtgtggaa accgcagtca gtccgggcag tccgggcagc gggcgggatg ccgtctgagg
    68041 gtcggtatgc agtgttttga atgcgacggc ggttaaaaac aggatgaaga aaatttgaag
    68101 cccgaacgcg gggatatatt ttgcggagag tgcgcccgtg aatacgccga atatcatacc
    68161 cggcatcatc gcaaatacgg ttttccagtc gaccgcctgt tttttgtgct gccccaacat
    68221 actggaaaag gcggtgaaga ccatgacggc gaaggatgtg ccgacggcga ggtgttgcgc
    68281 gtaaggatgt tgtgccaaac cctgcaaatc aagtacccat aaaacgacag ggacaatcag
    68341 cgtgccgccg cctacgccga acagaccggc aataaaacct gccgcactgc ctacggcaag
    68401 caggattaag ataatgtccc aatgccacat ttaatccgcc tttctgtatt ttttccagaa
    68461 tcggcgtgcc gccataatgt agccggacag gctgtatccg agaaagaaca ggaagaggac
    68521 gagcgacggt tcccaagtga ccagaagcag caataagacg gcaagcagca ttccgacaaa
    68581 ggggacttgt ctgcggatgt tgatttcttt aaaactccaa aaagggattt ggacaatcat
    68641 cgacaggccg gcaaacagtg tgatgcccaa tgcccaccag tggacggcgg ggaatttttc
    68701 gacgctgtgg ttgacccaaa tcagcccgac aatcagcgcg gcggcagtcg gactgggcac
    68761 gccgataaac cagcgtttgt ccaccttgcc gatgagtgtg ttgaacaggg cgaggcgcag
    68821 ggcggcgcag gcgcagtaga tgaaggcgac ggaataaccg attttgccga actgccaaag
    68881 ctgccatttg taggcaatca gagcgggagc aacgccgaag ctgaccatat cggcaaggct
    68941 gtcgagctgc tccccgaacg cgctttggct gttggtcagc cgcgccacgc gcccgtccat
    69001 accgtccagc aacatagaga tgaataccgc gatggcggcg gtttcataac gtccgtgcat
    69061 ggattgggtg attgcgtaaa atgcggaaaa cagcgcggcg atggtaaagg agttgggcag
    69121 caggtagata ctgttttgac gcagggagcg ttgcggggtg ttggtcgggg tttccatagc
    69181 tgaagtgtct cacggacgtg gagaatcgat aggggattat aacccaaacc attatcgaac
    69241 aatacgccct ttaggatgaa gccctcggag gcggtttgtt tttctgatgg cggatgcttt
    69301 gcggggcggt ttgactctgc ctgccaccgg gtgtgttgtt tcggattttt gccggatgga
    69361 tattgttgct gggcatttct gggcttgccg gaaggtatcg gggggagggc atcggaatat
    69421 gcggcgcacc gttcaaaccg gggcggcgtt tccctatttt cagggggttg caggtttcaa
    69481 caaattgaaa gatatttttt gcatttccga ccgtatgctg attttgaagc gggataaatt
    69541 ataggacaag gtttttcgcc cgccgcaaag gttggccgca atgccgtctg aaaacaacgg
    69601 cttgccgcta aggcggcggt atgcggattt gcgctgccga aatcggtttg ccatacccgg
    69661 cggtgcaatc tgcggggagg gataagccga taaggcggga cttatcctgt tttttgttta
    69721 taatgcaaca gaatttggac gaaccgtcgg gaatttatca tgatgaaaaa gatactggcc
    69781 gtatcggcac tatgcctgat gactgcggcg gcacgggctg ccgatactta cggctatctc
    69841 gccgtttggc agaatccgca gaatgcggac gatgttttgc aggttaaaac tacaaaagaa
    69901 gattcgacga aaagcgaagc gtttgccgag ttggaagcct tttgcaaagg tcaggacacg
    69961 cttgcgggca ttgccgaaga cgagccgacc ggatgccggt cggtcgtgtc gctgaacaat
    70021 acctgtgtcg cgctggcata cccgaaagcc ttgggcgtga tgcgcgttga aaacgccgtc
    70081 gtgattactt ctccgcgttt tacgagcgtt catcaggtcg cactcaacca gtgcatcaaa
    70141 aaatacggcg cacagggaca atgcggcttg gaaacagtgt attgcacgtc ttcttcttat
    70201 tacggcggaa ctgtgcgctc tttgattcaa aatctcaaat aaaacggaaa atgccgtctg
    70261 aaagatgttc agacggcatt tctatatcga cggtcaggat tctttcggat cgggcagcag
    70321 gctgttcaac ataatggcaa gtacggcgca caagcccacg ccggcaaagc tgaagctgcc
    70381 caatttgagc gtcatgccgc cgatgcccgt ggtcagtacc gagctgacga tgaccaggtt
    70441 tttcggcagc atcaaatcga ctttggcatc aatcagcgtt ttcacgccca aagaagcaat
    70501 cgtgccgaac agcagcagca taatgccgcc cattactggc atcggaatgg aagccaaaaa
    70561 cgcattgaat ttgccgaaaa acgccatgca gacggcaaaa accgccgccc aagtcatgat
    70621 gacggggttg ctgtttttgg taatcattac cgcacccgtt acttcgccgt aggtcgtaac
    70681 cggcgggccg ccgatcagac ccgcaacgca tacgcccaaa ccgtcgcctg caagggtttt
    70741 gtccaagccc gggtctttcg tatagtcttt ccccgtcaca ttgccgattg ccatgatgcc
    70801 gccgatgtgt tcgatggcgg gggcgacggc aacgggcagc ataaacagtg cagcctgcca
    70861 gttgacctga ggcgtttcaa aatggggaac ggcgaaccag ggcgcgtgtg caatgcttgc
    70921 cgtgtccacc agtcccatca gcagtgccaa aacataaccc gaagcgacac cgatcaagat
    70981 aggaatcagc ttcatcatcc tgctgccgaa aaccgatacg atggcggtaa cggcaaaggt
    71041 aaagccggaa agaatcagcg aatcggtata gtcgatgacc tgtttgccgt ccgcctgacc
    71101 cattgccatg ctgcttgccg ccacggcaac agacagaccg atgaccatga tgacggggcc
    71161 gatgacgacc ggaggcagca gtttgtgtac cgctgccagt ccgcgccaac ggatcagcgc
    71221 ggcaaacaca aaatacataa agccggcggc aaacagtccg aacatggtgg aaggcagccc
    71281 ccattcgccg acggagtaga taatcggtgc gataaaggca aacgaagaac caagaaaaat
    71341 cggcactttg cgtttggttg tgatttggaa cagcagcgtt cccaagcctg cgcccaaaag
    71401 cgcaagagcc ggattcagac cggtcagcag gggaaccagc accattgcgc cgaatgccac
    71461 aaataaaatc tgtgcaccgg aaacggcaag tttcagttgg tttataccat cttctttcaa
    71521 tcggttcaaa cggcacggat tatactggtt tgccgagggt ctgcgtaaaa atacatatgg
    71581 cgggcaacag atatgccgtc tgaaaggcaa tgtctgtctg ttgcaggatg aaagcaggag
    71641 aaatggagta taatccgaca ctttccatat tcaatccgca agccgtccgg cttccttatt
    71701 tcagacggca ttttccggta atacggcatg acagaaaaat cccataaaaa aacagcaaaa
    71761 ggcagggcgg gaagcccgtc cccaacgtcc gcacgcaaca agaaagccga caacggcgca
    71821 cggggcaata aagtttccga gcggctcaag gcggtcaaag agttgcagaa aaccgaaacc
    71881 aaaaaggcgc gtcccgaaca tgtcgtcaac cttatcggcg acgcactgtg gctgatgggt
    71941 ttggcggcaa ccctgtattt ggcgatttcc ctgatcagtt tcgatatggg cgatccgtct
    72001 tggtcgcaca gttcgccggt tgtggaagat gtcgccaatt ggggcggact gttcggcgcg
    72061 tatgttgccg atgtcggcta ttatcttttc ggctggtcgt tctggtggtg gatagcggct
    72121 gcctgcgtca tgctgtataa aaattttcgt ctgcacgcaa aacagacgga aaacgaggca
    72181 tacaaccaca aaatcgctgc cgccgcgctg tttgtcctga cggtcttcag ccccgtcttg
    72241 gagtattttg tgctgggcgg aaaatatgcc gactccctgc ctgtcggagc aggcggtatg
    72301 gtcggcatac gcgtcggcgc agtgtttgcg tggctgctgg ggaaatcggg cagcctgctg
    72361 attatcttgg ttgttctgct gttgtcgttg tccctgctgg tgcagatttc atggctggaa
    72421 tttttgaacg gtgcgggcag ggcggttcaa aaccgcctga gtgccttatc cggcaaggtc
    72481 atggctttag gaaaacgccg gccgaatagc aaaacagacg gtgtcgatac ccaaaataca
    72541 cggcgcatgg taaaagaagc caagaatatt acggccaaac ccgttgcctt gcccgaaggc
    72601 agcagcagca accgcaaatc cgtcgcggtt tccgtcgcgc cgtcgcccaa aattcaggtt
    72661 tctctgtttg aagatgacga acctcggcag gcgggcgaat accacaagcc tacattgaac
    72721 ctattgcgga ttcctgacag cgaacccgtc agcatcaatc ccgccgaatt ggagcgcact
    72781 gccgaactga tcgaatccaa actggcagaa ttcggcatcg gcgtacaagt cgtatccgcc
    72841 acatccggtc ccgtcatcac gcgctacgaa atcgaacccg cgcaaggtgt taaaggcagc
    72901 caaattgttg ccttgtcgaa agatttggca cgctctatgt cgctgcaatc cgtgcgtatc
    72961 gtcgaaacca tcgcaggtaa aaacacgatg ggcatcgagt tgcccaacga caaacgccaa
    73021 gacgtgatgt tgagcgaaat cttgtcctcg cccgtgtttg ccgaagccaa atccaagctg
    73081 accgtcgcgc tgggcaaaga cattgccggt acccccgttg tcggcgactt ggcgaaaatg
    73141 ccgcaccttt tggtcgccgg tatgactggt tcgggcaagt ccgtcggcgt gaacggcatg
    73201 attatgtcta tgcttttcaa agctacgccc gacgaagtcc gctttatcat gatagacccg
    73261 aaaatgcttg agttgagcat ttacgacggc attccgcacc tgctctgtcc cgtcgtgacc
    73321 gatatgcgcg aagcggggca ggcgttgaac tggtgcgtcg ccgaaatgga aaaacgctac
    73381 cgcctgcttt cccacgccgg tgtacgcaat ctggaaggct tcaaccaaaa agtcgaagcc
    73441 gcaaaagcgg caggcaagcc gctgctcaat ccgttcagtc tgaaccccga cagccccgag
    73501 cctttggaaa aactgccgat gattgtggtc gttatcgacg aacttgccga cctgatgatg
    73561 accgaacgca aagccgtcga gcagcaaatc gcccgtctcg cccaaaaagc gcgcgccgcc
    73621 ggtatccata tgattgtcgc cacccaacgt cccagtgtcg atgtcgttac tggcctgatt
    73681 aaagccaaca tcccgacgcg tatggcgttt accgtgcaaa gcaaaatcga cagccgtacc
    73741 atcctcgacc aaatgggcgc ggacgaactg ctcaaatatg gcgattcgct gttcctccag
    73801 cccggcagtg ccgaaccgac ccgcctgcaa ggcgcgtttg tttcagacga cgaagtacat
    73861 caagtcgtca actacgtcaa atcgcaagcc ccagccgact atattgaagg tctgctcagc
    73921 ggcgaggccg cgctggaaac tgccaatatc gttaatccga atgcagacag cgacgaattg
    73981 ttcgatcagg cagtcgccta tgttttggaa agcaaaaaaa cctccatttc gtctttgcag
    74041 cggcagttgc gtatcggcta taaccgcgcg gcaaacctga tggaggcact ggaaaatgcg
    74101 ggtgtcgttt ctcccaccga cctcaacggc agccgtaaaa ttttggcgca caaggaccat
    74161 ttgtagcccg tattgcaaaa tgccgtctga acggcggaat tggcgtttca gacggcatat
    74221 tatgtttcag gcggaacatt gtgatatact tgccagctaa aatctcccct ttgcggcaat
    74281 gcggttcaaa tatccgtacc gttgcgctgt ttgcttcccc atgcagggaa gaaggtttac
    74341 cattttatca acacaacaaa tttaagggct tatgatgagc gtaactgttg aaactttaga
    74401 aaatctggaa cgcaaagtag tgttgtccct gccttggtcc gaaatcaacg cagaaaccga
    74461 taaaaaactg aaacaaaccc agcgccgtgc aaaaatcgac ggtttccgcc cgggtaaagc
    74521 acctttaaaa atgattgccc aaatgtacgg tgcgagcgcg caaaacgacg tgatcaacga
    74581 gctggtgcaa cgccgcttcc acgatgttgc cgttgcccaa gagttgaaag tggcaggctt
    74641 cccccgtttt gaaggcgttg aagaacaaga cgataaagaa tctttcaaag ttgccgccat
    74701 ttttgaagtg ttccccgaag tcgttatcgg cgatttgtct gcacaagaag ttgaaaaagt
    74761 aaccgcttcc gtcggtgatg ccgaagtgga ccaaaccgta gaaatcctgc gcaaacaacg
    74821 cacccgcttc aaccatgtcg aacgcgaagc ccgaaacggc gaccgcgtca tcattgactt
    74881 tgaaggcaaa atcgacggcg aaccttttgc aggcggcgca tccaaaaact acgccttcgt
    74941 attgggcgca ggtcaaatgc tgcctgaatt tgaagccggc gtagtcggca tgaaggctgg
    75001 cgaaagtaaa gacgttaccg tcaacttccc tgaagaatac cacggcaaag acgttgccgg
    75061 taaaactgcc gtgttcacca ttacgctgaa caacgtttcc gaagcgactc tgcctgaagt
    75121 cgatgcagat tttgcaaaag ccttgggtat tgcggatggc gacgttgcca aaatgcgcga
    75181 agaagtgcag aaaaacgtaa gccgcgaagt ggaacgccgc gtaaacgaac aaaccaaaga
    75241 atccgtaatg aacgcgctgc tcaaagccgt agagctgaaa gcacctgttg ctttggtcaa
    75301 tgaagaagcc gcacgcttgg caaacgaaat gaaacaaaat tttgttaacc aaggtatggc
    75361 tgatgctgcc aacttggatc tgcctttgga tatattcaaa gaacaagccg aacgccgcgt
    75421 gtctttgggt ctgattttgg ccaaactggt tgatgaaaac aaactggaac cgactgagga
    75481 gcaagtcaaa gccgttgtcg ccaacttcgc agaaagctac gaagatcctc aagaagtaat
    75541 cgactggtac tacgcagagc cttcccgcct gcaagccccg acttctttgg cgatagaaag
    75601 caacgtcgtt gatttcgttt tgggtaaagc caaagtaaac gaaaaagctt tgtcttttga
    75661 cgaagtgatg ggtgcgcaag cctgattatc ctgaaaatgc cgtcttaggg cagtttttga
    75721 aagcaccgaa gccgctttta aagcccgctt tggtgctttt acatcatgaa aggagacgaa
    75781 atgtcttttg ataactatct tgtccctacc gttatcgagc agagcggtcg cggtgagcgt
    75841 gcattcgata tctattcccg gcttttgaaa gagcgcatcg tattcttggt cggtccggta
    75901 accgacgagt ccgccaatct ggtggttgcc caactgttgt ttttggaaag tgagaatccg
    75961 gataaggata ttttcttcta tattaactcg ccgggcggtt cggtaacggc cggtatgtcg
    76021 atttacgaca ccatgaattt tatcaagccc gatgtatcga ctttgtgctt ggggcaggca
    76081 gcaagtatgg gcgcgttctt attgtcggca ggcgaaaaag gcaaacgttt cgccctgccc
    76141 aacagccgga ttatgattca ccagccttta atcagcggcg gcttgggcgg tcaggcatcc
    76201 gatattgaaa ttcacgcacg cgaactgttg aaaatcaaag aaaaactcaa ccgcctgatg
    76261 gcgaaacatt gcggccgcga tttggcagat ttggagcgcg acaccgaccg tgataatttc
    76321 atgtccgccg aagaggctaa agaatatggt ctgattgatc aaatcttgga gaaccgtgct
    76381 tctttacagt tttaataaga aatctgagag aaacaaatgc cgtttgaaaa cagttcagga
    76441 cggcatttgt cttataggga ctgtataggg atgattttgt tctggttgcg tttggagccg
    76501 ttttcgccat aattggtttt aacatattcc tctacaatag ctaggaattc agttgcaata
    76561 ttatcacctt tcagtgtgac tttgcgctcc ccgtccacat aaaccggcgc gacgggtgtt
    76621 tctcccgtac cgggcaggct gatgccgatg tcggccaatt tgctttctcc gggcccattg
    76681 acaacgcagc ccatcacggc aacattcagg gattccacgc ctggataagc agtacgccat
    76741 acgctcattt tttgtcgcag gtaattttga acatcttgtg ccagctcttg aaatacggta
    76801 ctggtggtac gcccgcagcc ggggcaggcg gtaaccatcg gcgtaaacga acgcaatccc
    76861 atagtctgta aaatctcttg cccgacgacg acctcctgag tacgcgggct gccaggttcc
    76921 ggagtcagtg aaatgcggat ggtgtcgccg attccttctt gaagcaagac ggataatgcc
    76981 gccgttgatg cgacaatgcc tttgctgccc ataccggctt cggtcaaacc caaatgcagc
    77041 ggataggcgc aacggctgcc cagttcgcgg taaacctgaa tcaaatcctg aaccgcgctg
    77101 actttgcacg acaggatgat tttgtcttcg ggcagtccca atagaacggc tttttcggca
    77161 gattccaaag cggagacaat cagtgcttcc ttcgtcactt cttcgggcgg tttcggcgcg
    77221 gaagaagcga ggttggcatc catcatacgt ttggcgaggc tttgatccaa agaaccccag
    77281 tttacgccga tgcggacggc tttatcgttt tcagcagcag tccgaatcat aaaggcaaat
    77341 ttttcatcgc cttttacgcc tttgccgaca ttgccgggat tgatgcggta tttggacaat
    77401 gctttgccgc attctggaaa ttccgccaac aggcgttcgc cgttgaagtg gaaatcgccg
    77461 ataagcggtg tggcatagcc catatcgtcc aagcggcggc ggatttcggc aactttggac
    77521 gcggcttcgg ggctgttgac ggtaatacgc accatttcgg atccggcatc gctcaattcc
    77581 ttaatctgca atgcggtggc ttttgcatcg gcagtgtcgg tgttggtcat agattggata
    77641 acgacgggtg cttctgaacc gacggtaata tgatcgatgc ggacttgatg cgtcttgcgg
    77701 cgttggagtg tgttcatatg gtttgaatct gtttattgac cggtgaggac ggtttgcaat
    77761 tcttccgagt aggggaaatt cgcctgcaat tgtgcttcat attcgtatgc cgcctgtgcg
    77821 ttgccgaggg ctttggcaat tttccagcct agcagcaaat catcggcctg aaggacttct
    77881 accctgcttt ggtatttttt aaagtagtaa tcggcatcgc ccaactgccc ggccagcatt
    77941 ttggtgcgcg ccagttcttt aaatgcgggt gggaactgcg gctgggcggc gagggaacgt
    78001 ttcaaatagg cttccgccaa tccgaattgc ccctgttttg cgctgcatat gcctttattc
    78061 aggttggcaa tataaggggt cgggtaggtg gggtcggcca gggctttgtc gaaatatgcc
    78121 atagattcgg cagggcggtt gagcctgccg cacaggaacc aaccgtagtt gttgttgatt
    78181 tcggcactgt cgggtttgat ggagagggct tgccggaaac ttttctgcgc cttgtcgtta
    78241 actttcaggt attggtagat ttcggcacgg accagccagg caagctcgtt tttagggtct
    78301 gatttcaggg cgtcttcaat acttgccgtc gcctgacggt agtcctgacc gcgcatatat
    78361 tccattgcca actgggtttt gatattggaa acctgattgg ctttttctgc ccgcgagggg
    78421 cggtaggaag tgctgcacgc gcccaaggca aggacaagta ataaagagat tcgtttggat
    78481 ggcttaaaag gcataattac ccctgttgtc cgattaaaat ctgctgccat ttttgttggc
    78541 ggcgcgtttt atcctgaacc tgccccgcca actgtccgca ggcggcatcg atgtcgtcgc
    78601 cgcgcgtttt tcgtacggta acgacaaatc ctgcctgctg caaaatatcg cggaacacac
    78661 ggatgttctc attgctggag cgttcgtatc cggagtttgg gaagggattg aacggaatca
    78721 gattgaactt gcagggaaca tctgtgacca gttcgatcag ttcgcgcgca tgttgcgcct
    78781 tatcgtttat tccgtccaac atgacgtatt cgaaagtgat gaaatccctg ggtgctttga
    78841 ccagatagcg ttggcatgcg gccatcaatt ctttcaaggg atattttttg ttcaacggta
    78901 cgatttggtt gcggacttcg tcattggaag cgtggaggga aaccgccaaa gccaccggca
    78961 tgacatcgcg caacctgtcc atttggggaa ccatacccga agtggaaacg gttacgcggc
    79021 ggcggctcaa accgtagccg tggtcgtcca gcatgatgct taaggcggta acgacattgt
    79081 cgaagttcgc catcggctcg cccatgccca tcatgacgac gttggaaatc acgcgctcgt
    79141 ttttcggtgt aacgcccatc gctttgtttg cccaccacaa ttgcccgatg atttcggcag
    79201 cagtcaaatt gcggttgaag ccctgccggc cggtcgaaca aaatgtacat tccaaagcgc
    79261 agccgacttg tgaggaaatg cagagcgtgc cgcgatccga ttcggggatg aagacggttt
    79321 ccaccccgtt gcccgtaccg acatccaaaa gccattttcg agtgccgtct gaagattttt
    79381 gagacatcat cagcttggga atttcgatgc ctgcctgttc gttcagttta tggcgcaacg
    79441 attttgccaa atcggtcatt tcgtcaaaat tttgcgcgcc ggattggtgc atccaacgca
    79501 taacctgttt ggcacggaaa ggtttttcgc ccatatcggc aaaatgtcgg gtcagccctt
    79561 ggaggtcgta gttgagcaga ttggttttca tgtatttgtg tttttcttaa attaaggctt
    79621 caaataaaaa attgcagggc aggcaagttt gatttgaagc cttttgcaac agagttttca
    79681 gacggcatgg atatatttta tgccgtctga agaggagttg tgcggtgtat tgtatcaacg
    79741 ggggcagatt tcggtttggc tgaaaaagta ggcaatttcc aaagcggcat tttccggagt
    79801 gtccgagccg tgtacggcat tgatgctgac cgaagtggca aagtccgcgc gtatcgtgcc
    79861 ttcggcggct tcggcgggat tggtcgcccc catcagttcg cggtttttca gaacggcgtt
    79921 ttcgccttcc agtacttgaa tcataaccgg accgccggtc ataaattcaa ccaatccggc
    79981 gtagaagggg cggtctttat gaaccgcata aaattcttgc gcctctttga gggtaagctg
    80041 cttcattttg gcggcaacga ttttcagacc gttctcctca aagcggctgt atattttgcc
    80101 gatgacgttt ttgccgacgg catcgggttt gatgatggag atggtacgtt caatcgccat
    80161 gctatatcct tatttttact taagaagaat caaatcggta ttctatcaaa aaaataactt
    80221 atccgcctga atccttggga gatagggtca ggtgcggctg ttccaaataa acttcggact
    80281 gcatttcgac catccggctg gcggtgcggg taaattcttc ggcaaaatcg ccttccgtat
    80341 agatatggtt gacatctacc gcgccggtgg cacacagttt gacccggaaa tcgtagagta
    80401 cgtcaatcag ccaagtcagc cgccgcgcct ccgccttttc ttgcggtgag agttgttcca
    80461 aacctgaaat aaaaaccatt tcataatgtt cggccaaata cagatagtcg gactgtgagc
    80521 gggggccgaa gcacagtgcg cggaaatcaa accatatggc acggccggac tcggctttgt
    80581 ggggaatctc ccgaccgtgg atggtgctga tgccggggtt caaatcggta atgcctgtca
    80641 tttctttgaa cagttttgcc agttttgcct cattttcttc attggcaggc gtaaagaaaa
    80701 tctcggcggg gcggagggta cgcagtcggt agtcttcacc gccgtcaacg tttaagacgg
    80761 tcaggctgga ctcgatgagc gcgattgtgg gaagaaaact gctccggttt tgaccttgcg
    80821 ggtagagttc ggaaggcgcg tagtttgaag tcgccaccaa aacaacgccc tcgttaagca
    80881 ggttttccag cagacggcct aaaatcattg catccgcaat atcgctgaca tgaaattcgt
    80941 caaaacataa tacgcgggtt tctttggcaa tctcggcggc aacggatttc aacgggttgc
    81001 tttcgctttt cagggttttc agcctctggt ggatttctgc cataaaggca tgaaagtgga
    81061 cgcggcgttt gcggcggtaa gggaggcagc cgaaaaaagc gtccatcaga aagcttttgc
    81121 cgcgtccgac cccgccatag aaataaagcc ctttggggac ttgcggggaa cgcaaactcc
    81181 tgcctaaaaa acggtttctt ttgcgtttga acatcatcaa ttcggtccaa agccgatcga
    81241 ggtgttcgat ggcggctgcc tgcgcgtcgt cgcggatgaa gttgggcagt tgtgaggcag
    81301 cctgatacca ggtcagcggg ctgtggtttt caaacggcgg ggctttaaaa agttggtctc
    81361 tattactcat atttaacctt gttatacttc ttgcggcgga gaaagaaaat gcttaccgtc
    81421 ggtattataa atgatttcct tcaaacttgg cattttccgt ggaaaagaat aatgacgcgc
    81481 acaagggggt ataagcaaag gcggcgtttc aatatggtgc agatatgagc tcaaatgcct
    81541 tttatagtag attaaattta aaccagtaca gcgttgcctc gccttgccgt actatctgta
    81601 ctgtctgcgg cttcgtcgcc ttgtcctgat ttttgttaat ccactataat ccgtagagtc
    81661 ggctccttcc ggctcagacg gcatacgttt atgccggcac ttcttaccgc cctcgtgccg
    81721 gctatcccaa aactgctttg aacactgaac gctctttggt ttacttcaaa aacgcggcgt
    81781 gataagcaat atgttcgcca ataaaactgg cgatgaagta ataactatgg tcgtagcctt
    81841 tgtggaagcg cacatcgacc ggctggtttg ccgcacgaca ggtttcgata aaatcttcgg
    81901 tacgcaattg tgtcggcaaa aactcatctt ccaagccctg atcaatgcgt ataccttgca
    81961 ctttatagcc ttgttgaatg agcgagctgg catcatattg ctgccatttt tcacgatctt
    82021 cccctaaata agcagtaaag gccttttctc cccaaggcac gaggcttggc gataaaatag
    82081 gcgaaaaagc agaaacgctt tgataacgtt tccgatttcg cagtgccaat accaatgcac
    82141 cgtgtccgcc cattgaatgc cccataatgg aacgtttgcc gttagtagag aaatttgctt
    82201 caaccaaatc aggcaattcg ttcaagatat aatcatacat ttgataattc gtcgcccaag
    82261 gctgctcagt tgcattaaga taaaagcccg caccttgtcc taaatcgtaa gccgcatcgt
    82321 tcggcacttg ctctccgcga gggctggtat caggggcaac cacaatcact tgatgttctg
    82381 ctgcataaag ctgaaagcct gatttagtaa tgaaattttg ttccgtacac gtcaagccgg
    82441 aaagccaata aatcacacca agcggttgat tttccgaatt atttggcaaa tagacggcaa
    82501 atttcatctc gcattgaagc gtttgggcat catgagccca aacttgctgc aaaccgccaa
    82561 aaatttgatg ttgttcaatc agtttcatcg cataccttag tagtgaataa cggcgcggat
    82621 cgatttacct tcgtgcatta agtcaaaggc tttattgatt tgatcgagtg tcattgtgtg
    82681 ggttacaaac ggttctaact caatgtcgcc tttcattgaa tcttccacca ttttcggcag
    82741 ttcagagcga cctttcacac cgccaaatgc tgaacctttc cacacacggc ctgttaccaa
    82801 ctggaacgga cgcgttgaaa tttcttgtcc tgcacctgct acgccgatga taatggattg
    82861 accccaacca cgatgtgcac tttctaatgc ttgacgcatt acgtttacat tgccgataca
    82921 ttcaaaggta tggtcaatgc cccatttgtt gatgtctaac aacacatctt taattggttt
    82981 atcgtaatcg ttcgggttca aacaatccgt tgcaccgaac tgttttgcca actcaaattt
    83041 tgatggattg gtatcaatgg cgataatgcg gccggctttg gcttgacgcg caccttgcac
    83101 caccgccaaa ccaatcgcgc ctaagccaaa cacggcaaca gagtcgcctt cttgcacttt
    83161 tgccgtatta tgtaccgcac caatacctgt ggtaacgccg cagccgagca aacatacttg
    83221 ttcatggttg gcttcagggt tgattttcgc cagtgaaact tcggcaacaa cggagtattc
    83281 actgaaagtc gaacagccca tatagtgata aatcggctga ccttgataag aaaaacgcgt
    83341 cgtgccgtcc ggcattaagc ctttaccttg tgtatcacgc actgagacgc acaagttggt
    83401 tttacctgaa caacaaaact cacattcgcc acattcggcg gtgtaaagcg gaatcacgtg
    83461 atcacccggt tttacgcttg acacaccttc gcccacagca acgaccacac ccgcaccttc
    83521 gtgtccaagc accacaggga atacgccttc aggatcgctt cctgataatg taaacgcatc
    83581 agtatggcac acgccagtgt gggtattgcg gattaacacc tcgcctttac gcggcatttc
    83641 tacgtcgatt tccacaattt gtaagggttg gttaggggcg aatgccaccg ccgcacgaga
    83701 tttgatgctt gaatcggttt gtttcatttc cattgtcttt cctcttaatt cattgacaaa
    83761 gttgccttac ctgagcaaca tagcaacagt ttacacttta gagttaactc taaggcaagt
    83821 gttttttact g
//
LOCUS       DAXISH010000002        75070 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.002, whole genome shotgun sequence.
ACCESSION   DAXISH010000002 DAXISH010000000
VERSION     DAXISH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 75070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75070
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.002"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(123..551)
                     /locus_tag="ACFOV4_000078"
     CDS             complement(123..551)
                     /locus_tag="ACFOV4_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01244 family sulfur transferase"
                     /protein_id="HFC7618186.1"
                     /translation="MAILKLDEHLYISPQLTKADAEQIAQLGIKTVICNRPDREEESQ
                     PDFAQIKQWLEQAGVTGFHHQPVTARDIQKHDVETFRQLIGQAEYPVLAYCRTGTRCS
                     LLWGFRRAAEGMPVDEIIRRAQAAGVNLENFRERLDNARV"
     gene            complement(616..2364)
                     /locus_tag="ACFOV4_000079"
     CDS             complement(616..2364)
                     /locus_tag="ACFOV4_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M61 family metallopeptidase"
                     /protein_id="HFC7618187.1"
                     /translation="MIHYKITPSPLDHEWHILLTFTQDDDLPIEISLPNWVPGSYLIR
                     DFSRHITSIHASCNGTSMPLEQIAKNRWHAAAVRGEWQIRYTVYAFDLSVRGSFLTTE
                     RGFFDGSCLFLKVEGTETLPHRLELTGIPSEWRIATTLPETGRFVFQAASYAELIDRP
                     VEMGLIEFLDFEAAGIPHTIALSGIYPDFDRNRLVSDIKKICETELAVFSSPAPFQKY
                     LFLLHVGDHIYGGLEHTDSTALLADRHSLPPYGMTDADDTYTTLLGLFSHEYFHAWNV
                     KSIKPAAFVPYDLDKENYTEQLWAFEGITSYYDDLFLARSRTISPESYLNLLAQGITR
                     VQQTRGRLRQTLAESSFTAWNKFYKPDENSPNAIVSYYQKGALAALCLDLIIRNRSNG
                     RHSLDTLMDKLYREWRDTHSGIPEKHWQIRCQEITGLDLEDFFQKALYSTEDLPLAEC
                     LATAGVGLTFLPLPRQHGGGYAEHICPVPSAGDFGARFKQNTDHIVLTHVFNGGSAES
                     AALCPQDKIIALDGYACTDFTAQWARYHVNAKINIHFFRAGILRQTVLTVQAAAADTA
                     ILHITDRNLLDNWLFG"
     gene            2691..4124
                     /gene="ccoN"
                     /locus_tag="ACFOV4_000080"
     CDS             2691..4124
                     /gene="ccoN"
                     /locus_tag="ACFOV4_000080"
                     /EC_number="7.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045278 - plasma membrane respiratory
                     chain complex IV [Evidence IEA];
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit I"
                     /protein_id="HFC7618188.1"
                     /translation="MDTQTYNYKVVRQFAIMTVVWGIVGMLVGVIVAAQLFAPALDLS
                     NIGPWFHFGRLRPLHTNAVIFAFGGCGLIGTSYYVVQRTCNTRLFGGWLPAFTFWGWQ
                     AVIVAAVVSFPMGWTQGKEYAELEWPIDILITLVWVAYAIVFFGTIAKRKIKHIYVAN
                     WFYGGFILAVALLHIVNNISIPAGLMKSYPVYSGAIDAMVQWWYGHNAVGFFLTAGFL
                     GMMYYFVPKQAARPVYSYRLSVVHFWALIFTYMWAGPHHLHYTALPDWTQSLGMILSL
                     ILFAPSWGGMINGIMTLSGAWDKLRTDPILKFLIVSLSFYGMSTFEGPMMSIKTVNAL
                     SHYTDWTVAHVHAGALGWVGFVTIGSVYYMIPRLFGKEQMHSTKLVEAHFWIATIGVV
                     LYIAAMWIAGVMQGLMWSSLNDDGTLTYSFVESVKRTMPYYVIRFAGGLLYLSGMCIM
                     AYNVYRTAIGGKAVDAEIPAVSQTQHH"
     gene            4151..4762
                     /gene="ccoO"
                     /locus_tag="ACFOV4_000081"
     CDS             4151..4762
                     /gene="ccoO"
                     /locus_tag="ACFOV4_000081"
                     /EC_number="7.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit II"
                     /protein_id="HFC7618189.1"
                     /translation="MKLQQLAEEKIGVLIVFTLLVVSVGLLIEVVPLAFTKAATQPAP
                     GVKPYNALQVAGRDIYIREGCYNCHSQMIRPFRAETERYGHYSVAGESVYDHPFQWGS
                     KRTGPDLARVGGRYSDEWHRIHLLNPRDVVPESNMPAFPWLARNKVDVDATVANMKAL
                     RKVGTPYSDEEIAKAPEALANKSELDAVVAYLQGLGLALKNVR"
     gene            4767..4937
                     /locus_tag="ACFOV4_000082"
     CDS             4767..4937
                     /locus_tag="ACFOV4_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcoQ/FixQ family Cbb3-type cytochrome c oxidase
                     assembly chaperone"
                     /protein_id="HFC7618190.1"
                     /translation="MDINGIRALFTVWIFICFLLVLYIVFNRRNKKNYDNAANSIFDE
                     NQDAQDKKSENR"
     gene            4961..5872
                     /gene="ccoP"
                     /locus_tag="ACFOV4_000083"
                     /pseudo
     CDS             4961..5872
                     /gene="ccoP"
                     /locus_tag="ACFOV4_000083"
                     /inference="COORDINATES: protein motif:HMM:TIGR00782.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit III"
     gene            5948..6292
                     /locus_tag="ACFOV4_000084"
                     /pseudo
     CDS             5948..6292
                     /locus_tag="ACFOV4_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582195.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c5 family protein"
     gene            6494..7903
                     /locus_tag="ACFOV4_000085"
     CDS             6494..7903
                     /locus_tag="ACFOV4_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /protein_id="HFC7618191.1"
                     /translation="MDTQIKTEADNQSNRRYLTVWRWHFYAGLLVMPFLTLLAVTGLG
                     MLLFANITGKEGERIHVVPQATVQPLSVQAEAARSAVNPETSSVVQYIAPRADDMVAV
                     FRVNNEGKATMVAVDPYTAKVVSTMPRNQGWYYTMDEIHSDMMLGAAGDYLLETAASL
                     TIIMIISGLYLWWVKRRGIKAMLLPSKGRARSWWRNLHGTFGTWVSLILLLFCLSGIA
                     WAGIWGGKFVQAWSQFPAGKWGVEPNPVSVVPTHGEVLNDGKVKEVPWILELTPMPVS
                     GTTVGKDGINPDEPMTLETVDRFAREIGFKGRYQLNLPKGEDGVWTLSQDSMSYDMIS
                     PFADRTVHIDQYSGKILADIRFDDYNPFGKFMAASIALHMGTLGWWSVLANVVFCLAV
                     IFIGISGCVMWWKRRPSGAAGMVPPAQKIKLPVWWMMALPLLAIALIFPTALLAIAVI
                     WLLDTLLLSRIPVLRKWFK"
     gene            8004..11213
                     /gene="recC"
                     /locus_tag="ACFOV4_000086"
     CDS             8004..11213
                     /gene="recC"
                     /locus_tag="ACFOV4_000086"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HFC7618192.1"
                     /translation="MFYLYQSNRLETLAALFAHIQKVKPLKSALQPEQIIVQSQGMRR
                     YLNTCLARDLGVAANLAFSLPASLTWKLMKKLIPGIPELSPFAPEVMRWRLLDLFRSE
                     AFRNTAEFEDVRNVLQDYLGSGESADYQLAGQLADIFDQYLVYRPQWIDAWQQGRILG
                     LGDDEIWQSKLWRYLDDGRQSAPHRVALWEKLLAALDKDKLPERYFVFGISTMAPMYL
                     QLLHKLSEHCDVFVFALNPSGMYWGNVIEAAQILKGGGDPDLTQAGHPLLASLGKQGR
                     DFFDFLNEMEIEGETPVFEEGGRDTLLHALQTDIQNLKMPSENVGSVNTGDGSIRIVS
                     AHSPLRELQILKDKLLKILHEHPDWQPHDIAVLTPNIESYTPFIEAVFGQAQPGAQAL
                     PYSVSDVKISRRQPLFHALSCLFDLLESRFEVDKVLVLLETAPVLRRFGLTEDDLPLL
                     HDMVADLNVHWGLDGEMRGGTDQLFTWKQAVERMILGWMLPEGGNPMWQDVSAWYADV
                     NQTALFGRFAALLETLSDIVRIWRQPATIGEWVARCRDLLETLFQAEADDQKSVQNLE
                     NEWVKWQAETELAQFSGQLPQQTVIRHIRRFLDSESEAGFLRGGITFCSMVPMRSLPF
                     KVICLLGLNDGDFPRNTKAAVFDLIAKHPAKGDRARRDDDRYLFLEALISAREILYLS
                     YIGRDIRKDEELAPSSLLGELIDTVAAMAGIGSRQLAQNWIEQHPLQAFSRRYFQEGG
                     RSDGIFGTRTDYATALGQTPEPPQPFFDQPVENAEPVAEIGQDEFIRFWRNPVKVWLQ
                     QQLAWSEPHIGEAWEPAEPFEPQHADQIAETYIEARREGRDFAQTAARIGAESLLPSG
                     ELGRLWQQNFQTAAKQIDTAVLNSPKLPPLSYAIPSDGQILKGSLGNLYRCGQVFYAY
                     GKPNAPQRIAFLLEHLIFCAVMPSEAEMRQTFIVQSGETEILAEIAQDRALQLLSEWM
                     AFFNIGQNRPLPFFAKTSLATAEAFAQKQDWEAALKKAQTAYHGSKVSKGQKDYTEVA
                     LVFGNASQNPLEQPLFENLVRLLADTLAAAEKKEETGEA"
     gene            complement(11281..12849)
                     /gene="mtrF"
                     /locus_tag="ACFOV4_000087"
     CDS             complement(11281..12849)
                     /gene="mtrF"
                     /locus_tag="ACFOV4_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041421321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family antimetabolite efflux transporter
                     MtrF"
                     /protein_id="HFC7618193.1"
                     /translation="MSQTDTQRDGRFLRTVEWLGNMLPHPVTLFIIFIVLLLIASAAG
                     AYFGLSVPDPRPVGAKGRADDGLIHVVSLLDADGLIKILTHTVKNFTGFAPLGTVLVS
                     LLGVGIAEKSGLISALMRLLLTKSPRKLTTFMVVFTGILSNTASELGYVVLIPLSAII
                     FHSLGRHPLAGLAAAFAGVSGGYSANLFLGTIDPLLAGITQQAAQIIHPDYVVGPEAN
                     WFFMVASTFVIALIGYFVTEKIVEPQLGPYQSDLSQEEKDIRHSNEITPLEYKGLIWA
                     GVVFVALSALLAWSIVPADGILRHPETGLVSGSPFLKSIVVFIFLLFALPGIVYGRVT
                     RSLRGEQEVVNAMAESMSTLGLYLVIIFFAAQFVAFFNWTNIGQYIAVKGATFLKEVG
                     LGGSVLFIGFILICAFINLMIGSASAQWAVTAPIFVPMLMLAGYAPEVIQAAYRIGDS
                     VTNIITPMMSYFGLIMATVIKYKKDAGVGTLISMMLPYSAFFLIAWIALFCIWVFVLG
                     LPVGPGAPTLYPAP"
     gene            13183..13395
                     /locus_tag="ACFOV4_000088"
     CDS             13183..13395
                     /locus_tag="ACFOV4_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618194.1"
                     /translation="MKNEIQKIMDKYDPWHEDDFESYEDIAKDVSLMTDKTFIEHYLL
                     EVYSEENGHFDQENVHAMIEEIKNAI"
     gene            complement(13674..14306)
                     /gene="mtrR"
                     /locus_tag="ACFOV4_000089"
     CDS             complement(13674..14306)
                     /gene="mtrR"
                     /locus_tag="ACFOV4_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux system transcriptional
                     repressor MtrR"
                     /protein_id="HFC7618195.1"
                     /translation="MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTR
                     GALYWHFKNKEDLFDALFQRICDDIENCIAQDAEDAEGGSWAVFRHTLLHFFERLQSN
                     DIYYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKE
                     TAVIFIKSTLDGLIWRWFSSCERFDLGKTAPRIIGIMMDNLENHPDLRRK"
     gene            14714..15952
                     /gene="mtrC"
                     /locus_tag="ACFOV4_000090"
     CDS             14714..15952
                     /gene="mtrC"
                     /locus_tag="ACFOV4_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit MtrC"
                     /protein_id="HFC7618196.1"
                     /translation="MAFYAFKAMRAAALAAAVALVLSSCGKGGDAAQGGQPAGREAPA
                     PVVGVVTVHPQTVALTVELPGRLESLRTADVRAQVGGIIQKRLFQEGSYVRAGQPLYQ
                     IDSSTYEAGLESARAQLATAQATLAKADADLARYKPLVAAEAVSRQEYDAAVTAKRSA
                     EAGVKAAQAAIKSAGINLNRSRITAPISGFIGQSKVSEGTLLNAGDTTVLATIRQTNP
                     MYVNVTQSASEVMKLRRQIAEGKLLAADGVIAVGIKFDDGTVYPEKGRLLFADPTVNE
                     STGQITLRAAVPNDQNILMPGLYVRVLMDQVAVDNAFVVPQQAVTRGAKDTVMIVNAQ
                     GGMEPREVTVAQQQGTNWIVTSGLKDGDKVVVEGISIAGITGAKKVTPKEWASSENQA
                     AAPQSGVQTASEAKTASEAE"
     gene            15964..19167
                     /gene="mtrD"
                     /locus_tag="ACFOV4_000091"
     CDS             15964..19167
                     /gene="mtrD"
                     /locus_tag="ACFOV4_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MtrD"
                     /protein_id="HFC7618197.1"
                     /translation="MAKFFIDRPIFAWVISIFIIAAGIFGIKSLPVSQYPSVAAPTIT
                     LHATYPGASAQVMEDSVLSVIERNMNGVEGLDYMSTSADSSGSGSVSLTFTPDTDENL
                     AQVEVQNKLSEVLSTLPATVQQYGVTVSKARSNFLMIVMLSSDVQSTEEMNDYAQRNI
                     VPELQRIEGVGQVRLFGAQRAMRIWVDPKKLQNYNLSFADIGSALSAQNVQISAGSIG
                     SLPAVRGQTVTATVTAQGQLGTAEEFGNVILRANTDGSNVYLKDVARVGLGMEDYSSS
                     TRLNGVNTTGMAVMLSNSGNAMATAKAVKERMATLEKYFPQGMSWKTPYDTSKFVEIS
                     IEKVIHTLIEAMVLVFVVMYLFLQNIRYTLIPTIVVPISLLGGFAFISYMGMSINVLT
                     MFAMVLVIGIVVDDAIVVVENVERIMAGEGLPPKEATKKAMGQISGAVIGITAVLISV
                     FVPLAMFSGATGNIYKQFALTMASSIAFSAFLALTLTPALCATMLKTIPKGHHEEKKG
                     FFGWFNKKFNSWTHGYEGRVAKVLRKTFRMMVVYIGLAVVGVFLFMRLPTSFLPTEDQ
                     GFVMVSVQLPAGATQERTNATLAQVTQLAKSIPEIENIITVSGFSFSGSGQNMAMGFA
                     ILKDWNERTAPGSDAVAIAGKLTGMMMGTLKDGFGIAVVPPPILELGNGSGLSINLQD
                     RNNTGHTALLAKRNELIQKMRASGLFDPSTVRAGGLEDSPQLKIDINRAAAAAQGISF
                     ADIRTALASALSSSYVSDFPNQGRLQRVMVQADEDARMQPADILNLTVPNKSGVAVPL
                     STIATVSWENGTEQSVRFNGYPSMKLSASPATGVSTGQAMAAVQKMVDELGGGYSFEW
                     GGQSREEAKGGSQTLILYGLAVAAVFLVLAALYESWSIPLAVILVIPLGLIGAAAGVT
                     GRNLFEGLLGSVPSFANDIYFQVGFVTVMGLSAKNAILIIEFAKDLQAQGKSAVEAAL
                     EAARLRFRPIIMTSFAFILGVVPLYIAGGASSASQRAIGTTVFWGMLIGTLLSVFLVP
                     LFYVVVRKFFKETAHEHEMAVKHAAEAGITGSDDSQH"
     gene            19222..20625
                     /gene="mtrE"
                     /locus_tag="ACFOV4_000092"
     CDS             19222..20625
                     /gene="mtrE"
                     /locus_tag="ACFOV4_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MtrE"
                     /protein_id="HFC7618198.1"
                     /translation="MDTTLKTTLTSVAAAFALSACTMIPQYEQPKVEVAETFKNDTAD
                     SGIRAVDLGWHDYFADPRLQKLIDIALERNTSLRTAVLNSEIYRKQYMIERNNLLPTL
                     AANANDSRQGSLSGGNVSSSYKVGLGAASYELDLFGRVRSSSEAALQGYFASTANRDA
                     AHLSLIATVAKAYFNERYAEEAMSLAQRVLKTREETYKLSELRYKAGVISAVALRQQE
                     ALIESAKADYAHAARSREQARNALATLINQPIPEDLPAGLPLDKQFFVEKLPAGLSSE
                     VLLDRPDIRAAEHALKQANANIGAARAAFFPSIRLTGTVGTGSAELGGLFKSGTGVWS
                     FAPSITLPIFTWGTNKANLDAAKLRQQAQIVAYEAAVQSAFQDVANALAAREQLDKAY
                     DALSKQSRASKEALRLVGLRYKHGVSGALDLLDAERSSYSAEGAALSAQLTRAENLAD
                     LYKALGGGLKRDTQTDK"
     gene            complement(20817..21014)
                     /locus_tag="ACFOV4_000093"
                     /pseudo
     CDS             complement(20817..21014)
                     /locus_tag="ACFOV4_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003757319.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21014..21220)
                     /locus_tag="ACFOV4_000094"
                     /pseudo
     CDS             complement(21014..21220)
                     /locus_tag="ACFOV4_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311098.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015727 - lactate transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
     gene            21827..22606
                     /locus_tag="ACFOV4_000095"
     CDS             21827..22606
                     /locus_tag="ACFOV4_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFC7618199.1"
                     /translation="MKLVRPQKISDQVLSVLEERIAEGVYAEGGKIPPERVLAEEFGV
                     SRPSVRSALNVLVARQVLEARQGDGYYVSVKPQQDFLQSWQELLGKHSNWEQDVFDFS
                     CHIEGCMAALAAERRTDADLKRIGFWLEKFEEACESGNLEHQSEADVSFHQTIADAAH
                     NLLFSHLSGGLLKMLYRQTRSSLIYLNQEEDPRPKLMAQHRVLYEAISNRRPGEASEA
                     AKAHLNYVASSIMKDREYQSRNRHADTLAQNDLKRVQDWEV"
     gene            complement(22792..23049)
                     /locus_tag="ACFOV4_000096"
     CDS             complement(22792..23049)
                     /locus_tag="ACFOV4_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone acetyltransferase"
                     /protein_id="HFC7618200.1"
                     /translation="MIELKLVDESSFQAVLDLKISEADERARFVAPNVRSLADAWLYR
                     ENEDVFPRAIYWDKQVVGFLLLEIDKDEAEYFIWRIMIGQQ"
     gene            complement(23093..23467)
                     /locus_tag="ACFOV4_000097"
     CDS             complement(23093..23467)
                     /locus_tag="ACFOV4_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618201.1"
                     /translation="MIMDQYYMELKNKLSNRPILLDNTNDFLFVLVNTVKAMIENTDK
                     SQLSELDKILDGVTSQELKLAYDFCQGKFGQAGFSYRRHPNYFYLSSLIATFPEFELS
                     KADRDYLKGIINFDNYLLYELD"
     gene            complement(23609..24943)
                     /gene="gdhA"
                     /locus_tag="ACFOV4_000098"
     CDS             complement(23609..24943)
                     /gene="gdhA"
                     /locus_tag="ACFOV4_000098"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFC7618202.1"
                     /translation="MTDLNTLFANLKQRNPNQEPFHQAVEEVFMSLDPFLAKNPKYTQ
                     QSLLERIVEPERVVMFRVTWQDDKGQVQVNRGYRVQMSSAIGPYKGGLRFHPTVDLGV
                     LKFLAFEQVFKNALTTLPMGGGKGGSDFDPKGKSDAEVMRFCQAFMTELYRHIGADTD
                     VPAGDIGVGGREIGYLFGQYKKIRNEFSSVLTGKGLEWGGSLIRPEATGYGCVYFAQA
                     MLQTRNDSFEGKRVLISGSGNVAQYAAEKAIQLGAKVLTVSDSNGFVLFPDSGMTEAQ
                     LAALIELKEVRRERVATYAKEQGLQYFENQKPWGVAAEIALPCATQNELDEEAAKTLL
                     ANGCYVVAEGANMPSTLGAVEQFIKAGILYAPGKASNAGGVATSGLEMSQNAIRLSWT
                     REEVDQRLFGIMQSIHESCLKYGKVGDTVNYVNGANIAGFVKVADAMLAQGF"
     gene            25327..26121
                     /locus_tag="ACFOV4_000099"
     CDS             25327..26121
                     /locus_tag="ACFOV4_000099"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFC7618203.1"
                     /translation="MKAYLDLMRHVLDNGTDKSDRTGTGTRSVFGYQMRFDLGKGFPL
                     LTTKKLHLRSIIYELLWFLKGDTNIKYLKDNNVSIWDEWADENGDLGPVYGYQWRNWP
                     APDGRHIDQIANVVEQIKKNPDSRRLIVSAWNPALVDEMALPPCHALFQFYVADGKLS
                     CQLYQRSADIFLGVPFNIASYALLTMMMAQVCGLEAGEFVHTFGDAHLYRNHFEQAAL
                     QLEREPRALPVMKINPEVKDLFSFKFEDFELEGYDPHPHIKAAVSV"
     gene            26130..26727
                     /locus_tag="ACFOV4_000100"
                     /pseudo
     CDS             26130..26727
                     /locus_tag="ACFOV4_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222110.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
     gene            complement(26962..28299)
                     /locus_tag="ACFOV4_000101"
     CDS             complement(26962..28299)
                     /locus_tag="ACFOV4_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HFC7618204.1"
                     /translation="MSNHTSWSSKIGFVLAAAGSAIGLGAIWKFPYTAGTNGGAVFFL
                     LFLIFTVLVALPVQLAEFYIGRTGGKNAVDSFRALRPSTQWLWVGRMGVSACFILLSF
                     YSVVGGWVLNYVVHSFTGAVHTGADFEALFGATISNPAGSLSYQALFMLITVWVVKGG
                     ISDGIEKANRYLMPGLFILFIALAIRSLTLPGAMEGVSFLLKPNWSYFKADTMITALG
                     QAFFALSIGVSAMITYASYLGKDQDMFRSGHTIMWMNLLVSLLAGLVIFPAVFAFGFE
                     PSQGPGLIFIVLPAVFMKMPFGTVLFAVFMLLVVFATLTSAFSMLETVIAATIRQDER
                     KRKKHTWLIGTAIFIVGIPSALSFGVWGEFKVFGKTIFDLWDYLISAVIMPVGALSVA
                     VFTAWIQDRQSVLKDAGAGSTVPRAVLLLWLNTLRYLAPIAIIIVFINSLDIL"
     gene            complement(28686..29750)
                     /locus_tag="ACFOV4_000102"
     CDS             complement(28686..29750)
                     /locus_tag="ACFOV4_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFC7618205.1"
                     /translation="MEKEFRILNIVSAKIWGGGEQYVYDVSKALGLRGCTMFTAVNKN
                     NELMHRRFSEVSSVFTTRLHTLNGLFSLCALTRFIRKNRISHLMIHTGKIAALSILLK
                     KLTGVRLIFVKHNVVANKTDFYHRLIQKNTDRFICVSRLVYDVQTADNPFKAKYRIVH
                     NGIDTGRFPPSQEKPDSRFFTVAYAGRISPEKGLENLIEACVILHRKYPQIRLKLAGD
                     GHPDYMCRLKRDVSASGAEPFVSFEGFTEKLASFYRQSDVVVLPSLVPEAFGLSLCEA
                     MYCRTAVISNTLGAQKEIIEHHQSGILLDRLTPESLADEIERLVLNPETKNALATAGH
                     QCVANRFTINHTADKLLDAI"
     gene            complement(29751..30509)
                     /locus_tag="ACFOV4_000103"
     CDS             complement(29751..30509)
                     /locus_tag="ACFOV4_000103"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFC7618206.1"
                     /translation="MKKVSVLIVAKNEANHIRECIESCRFDKEVIVIDDHSTDNTAEI
                     AEGLGAKVFQRHLNGDFGAQKTFAIEQAGGEWVFLIDADERCTPELSDEISKIVQTGD
                     YAAYFVERRNLFPNHPATHGAMRPDSVCRLMPKKDSSVQGKVHETVQTPYPKRRLKHF
                     MYHYTYDNWEQYFNKFNKYTSISAEKYREQGKPVRFVRDIILRPIWGFFKIYILNKGF
                     LDGKMGWIMSVNHSYYTMIKYVKLYYLYKSGGKF"
     gene            complement(30584..30659)
                     /locus_tag="ACFOV4_000104"
     tRNA            complement(30584..30659)
                     /locus_tag="ACFOV4_000104"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30624..30626),aa:Ile,seq:cat)
     gene            complement(30713..31822)
                     /locus_tag="ACFOV4_000105"
     CDS             complement(30713..31822)
                     /locus_tag="ACFOV4_000105"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase"
                     /protein_id="HFC7618207.1"
                     /translation="MEAQLGAPIEDYAPPKHWTRKQLRSMGRVSYLCVDAAEQALTDA
                     GLLGDESITDGRMGVACGSSSGSTKDIGDVGELLLTGTSRNFSANTYVRMMPHTTAAN
                     IGIFFGLKGRIIPTSSACSSGSQGIGYAYEAIKYGLTDMMLAGGGEEFFSSEVYVFDS
                     LYAASRRNGEPEKTPRPYDANRDGLVIGEGAGIFVLEELEHAKRRGAIIYAELVGYGA
                     NSDAYHISTPRPDAQGAILAFQTALQHAGLAPEDIGWINLHGTGTHHNDSMESRAVAA
                     VFGNNTPCTSTKPQTGHTLGAAGAIEAAFAWGIADRQSNPEGKLPPRLWDGQNDPDLP
                     AINLTGSGSRWETEKHIAASSSFAFGGSNCVLIIG"
     gene            complement(31826..32390)
                     /locus_tag="ACFOV4_000106"
                     /pseudo
     CDS             complement(31826..32390)
                     /locus_tag="ACFOV4_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611451.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            32437..32937
                     /locus_tag="ACFOV4_000107"
                     /pseudo
     CDS             32437..32937
                     /locus_tag="ACFOV4_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714696.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl synthase chain length factor"
     gene            32940..33023
                     /locus_tag="ACFOV4_000108"
                     /pseudo
     CDS             32940..33023
                     /locus_tag="ACFOV4_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222119.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
     gene            33304..33738
                     /locus_tag="ACFOV4_000109"
     CDS             33304..33738
                     /locus_tag="ACFOV4_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003790506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618208.1"
                     /translation="MCGLWLLRALTAKLPQQRYAALFITLFFAAVLVFGRHDSMYWYP
                     VLVNLMMLAVFGGSLFAGQTVIERLARLQQPDLPEKAVRYTRRVTQVWCVFFIANGTL
                     AALLARLGRYDWWAVYTGVIAYVLMGMLFAGEWLYRKLVLKV"
     gene            33745..34260
                     /locus_tag="ACFOV4_000110"
     CDS             33745..34260
                     /locus_tag="ACFOV4_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2199 domain-containing protein"
                     /protein_id="HFC7618209.1"
                     /translation="MYTCTSCGEKHEDMPAIGFTAPDPYNQLSEEERIAYQAECDSDF
                     CIIRYPDQTDRFIRAVLPIPIIGHEETLEYGVWVSVSEKSFNDYQSHFHDNPENAVYF
                     GMICNRLPSYESDTFGLHCNVVTQPDGQRPLLQLHQSGGHPLVRDFYHGIEYAEAQAR
                     IGAVSESDCSG"
     gene            34280..35758
                     /gene="ubiD"
                     /locus_tag="ACFOV4_000111"
     CDS             34280..35758
                     /gene="ubiD"
                     /locus_tag="ACFOV4_000111"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HFC7618210.1"
                     /translation="MKYKDLRDFIVMLEQQGKLKRVAHPVSPHLEMTEIADRVLRAEG
                     SALLFENPIKPDGTRYDYPVLANLFGTPERVAMGMGADSVSKLREIGQTLAYLKEPEP
                     PKGIKDAFSKLPLLKDIWSMAPNVVKNAPCQEIVWEGENVDLYKLPIQHCWPEDVAPL
                     VTWGLTVTRGPHKKRQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEFRKLNPDTSYP
                     VSVVLGCDPATILGAVTPVPDTLSEYQFAGLLRGSRTELVKCIGNDLQVPARAEIVLE
                     GVIHPNETALEGPYGDHTGYYNEQDYFPVFTVERITMRENPIYHSTYTGKPPDEPAVL
                     GVALNEVFVPLLQKQFPEITDFYLPPEGCSYRMAVVSMKKQYAGHAKRVMMGCWSFLR
                     QFMYTKFIIVVDDDVNVRDWKEVIWAVTTRMDPVRDTVLVDNTPIDYLDFASPVSGLG
                     GKMGLDATNKWPGETDREWGRVIKKDPAVTAKIDGIWGELGL"
     gene            complement(35823..37937)
                     /locus_tag="ACFOV4_000112"
     CDS             complement(35823..37937)
                     /locus_tag="ACFOV4_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HFC7618211.1"
                     /translation="MDLLSVFHKYRLKYAVAVLTILLLAAIGLHASVYRILTPENIRS
                     RLQQSIAHTHRKISFDADIQRRLLPRPTVILKNLTITEPGGDRTAVSVQETKIGLSWK
                     NLWSDQIQIEKWVVSSAELALTRDGKGVWNIQDLIDSQKRQASVNRIIVENSTVRLNF
                     LQEQLILKEINLNLQSPDSSGQPFESSGILVWGKLSVPWKSRGLFLSDGIGTPKISPF
                     HFEASTSLDGHGITISTTGSPSVRFNAGGADAAGLGLRADTSFRNLHLTAQIPTLALR
                     NNSIKIETVNGAFTIGGEYARWDGSFKLDKANLHSGIANIGNAEISGSFKTPRHQTNF
                     SLNSPLVWTENKGLDAPRLYVSTLQDTVNRLPQPRFISRLDGSLSVPNLQNWNAELNG
                     TFDRQTVAAKFRYTHEDAPHLEAAVALQKLNLTPYLDDVRQQNGKIFPDTLAKLSGDI
                     EAHLKIGKVQLPGLQLDDMETYLHADKDHIALSRFKSGLYGGHTEGGISIANTRPATY
                     RLQQNASNIQIQPLLQDLFGFHSFSGNGDAVIDLTAGGETRKELIRSLQGSLSLNISN
                     GAWHGIDMDNILKNGISGKTADNAAPSTPFHRFTLNSEISDGISRHIDTELFSDSLYV
                     TSNGYTNLDTQELSEDVLIRNAVHPKNKPIPLKITGTVDKPSITVDYGRLTGGINSRK
                     EKQKILEDTLLEQWQWLKPKEP"
     gene            38028..38921
                     /locus_tag="ACFOV4_000113"
     CDS             38028..38921
                     /locus_tag="ACFOV4_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFC7618212.1"
                     /translation="MIIVMSRRAAEADIAGVVAFIRSRGLREHISHGDERTVIGAIGD
                     DRVLSVREVQTLPEVEKAVRILDTWKTVSRENRAEDSRVAAKGVAFGGGETVRIAAEP
                     SVWRNADAVFLDPFFTSANLYDTSSADEGRGRCRRLAEQTASAHGAGKPVLVRVRNVR
                     HVEAALNAGADILYLGGGLMSDLAVLNEAGSLNIPLVLCKDKHHSAEDWLNAAEYVVS
                     RGNRHLILGESGVLSHTKDHPYRLDVESIVKVRQISHLPVIANITGLWNRDMPQEILY
                     GLAKAAGACGIVGTCFEKSGG"
     gene            39061..39912
                     /gene="folP"
                     /locus_tag="ACFOV4_000114"
     CDS             39061..39912
                     /gene="folP"
                     /locus_tag="ACFOV4_000114"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HFC7618213.1"
                     /translation="MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGAYSQNARTA
                     LAHAERLLKEGADILDIGGESTRPGADYVSSEEEWARVEPVLAEVAGWGVPVSLDTRR
                     TVIMEKALALGGIDIINDVAALTDEGAVELLARQTDTGICLMHMRGLPENMQINPKYQ
                     DVVGEVARYLKARAAECIAAGIAPQRITLDPGFGFGKTLQHNIALMRHLPELMAETGF
                     PLLIGVSRKRMVGELTGETDAAARVHGSVAAAVAAVARGAQIVRVHDVKATADALKVW
                     EALGINL"
     gene            40042..41376
                     /gene="glmM"
                     /locus_tag="ACFOV4_000115"
     CDS             40042..41376
                     /gene="glmM"
                     /locus_tag="ACFOV4_000115"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFC7618214.1"
                     /translation="MAKKYFGTDGVRGEVGQFPITPDFVLKLGYAAGQVLVQHDTDQK
                     PTVLIGKDTRISGYMLEAALVAGFTAAGVNVVQTGPLPTPGVAYLTRALRLSAGVMIS
                     ASHNAYSDNGIKFFAEGGVKLSDEIELEIEAKIDEEMKTQPSARLGRARRISGADDRY
                     IEFCKSTFPSHSDLRGLKLVIDTANGAGYGVAPKVFHELGAQVVSIGDEPNGYNINEK
                     CGATYTKTLQAAVLQHEANYGIALDGDGDRLMMVDKNGKVYDGDSLIYVIAKARAREG
                     INIGGVVGTVMTNMAMENALKEQGVDFCRAKVGDRYVLEQLNQRGWLIGGEASGHILC
                     MDKHNTGDGIISALQVLAALQTLNQDLATVCADWQPYPQTMINVRIGKGQNWQEASKD
                     VLAEVEKELEGKGRVVLRASGTEPVVRVMVEARQADWARDGAERIASAIGSL"
     gene            41565..42248
                     /locus_tag="ACFOV4_000116"
     CDS             41565..42248
                     /locus_tag="ACFOV4_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFC7618215.1"
                     /translation="MFALLEAFFVEYGYAAVFFVLVICGFGVPIPEDLTLVTGGVISG
                     MGYTNPHIMFAVGMLGVLVGDGIMFAAGRIWGQKILKFKPIARIMTPKRYAQVQEKFD
                     KYGNWVLFVARFLPGLRTAVFVTAGISRKVSYLRFLIMDGLAALISVPVWIYLGEYGA
                     HNIDWLMAKMHSLQSGIFIALGVLAAALAWFWWRKRRHYQLYRAQLSEKRAKRKAEKA
                     AKKAAQKQQ"
     gene            42315..43307
                     /locus_tag="ACFOV4_000117"
     CDS             42315..43307
                     /locus_tag="ACFOV4_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFC7618216.1"
                     /translation="MKQKIFVLYTGGTIGMTQSSEGLRPDTALVGQALAPFSNGMDFD
                     WHVCGTLIDSSAVQLQNWCAWLDIIAAALPQYDGVLVLHGTDTLAYTANLFALALQGL
                     DKPIVLTGSQWSYNAVGSDAPRNLATAVAAFPLGLKQTLIAFDGKLYPAVGSSKVSTE
                     TASGFDNPHFGVIAEWDETQGWYNLRIPSQDAAAVSDGLKIRYPDPQAKIAVRTLIPG
                     FAVQELADGLGQLPAHALILQSYGHGNTPADEGFIRAVQDFTQQGKLLLNISQVRQGR
                     TAAVYAQGNAFRNSGIINGGKCNLETATALMTLAVSEGWGAEDVHKELVRLKLV"
     gene            43315..44085
                     /locus_tag="ACFOV4_000118"
     CDS             43315..44085
                     /locus_tag="ACFOV4_000118"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFC7618217.1"
                     /translation="MNFTDTHCHLADPALRENLPHILTAARKVGVKRFIVPATCPQDW
                     QSVAELSEMPSEHGQIRIALGIHPWFSDGIAERDFVRLEAMLARYPQAWVGEIGLDFY
                     DKTQTPPQRERQIQVFVRQLAIAQTLRRRVIIHNLKATADIAAAVKQTGFAQGGIVHA
                     FSGSAEEARVLTKLGFKIGIGSLLLNPNARKVRDTLKALNDGDFVLETDSPFMLKKEI
                     NTPANIPGIAKIAAEIRGTCVEEIAKVTERNADALLGR"
     gene            44189..45265
                     /gene="prfA"
                     /locus_tag="ACFOV4_000119"
     CDS             44189..45265
                     /gene="prfA"
                     /locus_tag="ACFOV4_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003790927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFC7618218.1"
                     /translation="MKPSILEKLQQLGDRLEEVTHLLGQPEATSDMDNYRKLTREHAE
                     LTPVVEVFQNYQLAQSDLADAEEMLSDPEMKDFAAEEIEAAKAKIGALDTELQKLLLP
                     KDADDDKNIFIEVRAGTGGDEAALFAGDLLRMYSRYAERNRWQVEIVSANESELGGYK
                     EVIARIIGLGAYSRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPEADELEDIELN
                     PVDLRIDTFRASGAGGQHINKTDSAVRITHLPTGMVVECQDGRSQHANKAQAMKVLAA
                     RLNDAQKREAQAKEAAERKSLIGSGDRSERIRTYNYPQGRVTDHRINLTLHKLDFVMD
                     GDLAEITDALIAEHQAELLAAMGD"
     gene            45390..46388
                     /locus_tag="ACFOV4_000120"
     CDS             45390..46388
                     /locus_tag="ACFOV4_000120"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008720 - D-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0070404 - NADH binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFC7618219.1"
                     /translation="MKIAIYGTKSYDREHFTRANRHFGFELEFFDFMLDAKTAKMAEG
                     AEAVCIFVNDDGSRPVLEKLAQIGVKTVALRCAGFNNVDLKAAEELGLKVVRVPAYSP
                     ESVAEHTVGLMLTLNRRIHKAYQRTRDANFSLEGLTGFNMYGKTAGVIGTGKIGIATM
                     RILKGFGMNLLAHDPFCNPEAEKIGGRYVDLDELYAQSDIITLHCPATPENHYMLNEA
                     AFDKMKDGVMIINTSRGGLIDSAAAIEALKRRKIGALGMDVYENERELFFEDKSNDVI
                     TDDVFRRLSSCHNVLFTGHQAFLTEEALGNISEVTLSNIREVGQIGDCGNAVRADG"
     gene            complement(46466..47761)
                     /gene="serS"
                     /locus_tag="ACFOV4_000121"
     CDS             complement(46466..47761)
                     /gene="serS"
                     /locus_tag="ACFOV4_000121"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFC7618220.1"
                     /translation="MLDIQSLRSNTAAVAERLAARGYEFDAARFNALEEQRKAVQVKT
                     EELQASRNSISKQIGALKGQGRHEEAQAAMDQVAQIKTDLEQAAADLDAVQKELDAWL
                     SGIPNLPHESVPAGKDETENVEVRRVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSG
                     ARFTVMRGQIARLHRALAQFMLDTHTLKHGYTEHYTPYIVDDTTLQGTGQLPKFAEDL
                     FHVTRGGDESKTTQYLIPTAEVTLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGK
                     DTRGLIRQHQFDKVEMVQIVHPEKSYETLEEMVGHAENILKALELPYRVITLCTGDMG
                     FGATKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGL
                     AVGRTLVAVLENHQNADGSINIPAALQPYMGGVAKLEVK"
     gene            47927..48451
                     /locus_tag="ACFOV4_000122"
     CDS             47927..48451
                     /locus_tag="ACFOV4_000122"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HFC7618221.1"
                     /translation="MLDREGYRPNVGIILINNRNEVFWGKRVREHSWQFPQGGIKPGE
                     SPETAMYRELYEEVGLLPQHVKIVGRTRDWLRYDVPNNWVRREWRGSYRGQKQIWYLL
                     RLTGRDCDVNLRATRHPEFDGWRWHQYWAPVDEVIDFKRDVYLGALKELSTRFLRGME
                     SYEDFAARQPSDNR"
     gene            48518..50503
                     /gene="parE"
                     /locus_tag="ACFOV4_000123"
     CDS             48518..50503
                     /gene="parE"
                     /locus_tag="ACFOV4_000123"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFC7618222.1"
                     /translation="MAKNNQYSESSITVLKGLEPVKERPGMYTRTDSPTHICQEVIDN
                     AADEALGGFATAIDVQIHEDGSLSVHDNGRGIPVGLHPEEGVPVVELVFTRLHAGGKF
                     NKKDGGSAYAFSGGLHGVGVSVTNALSTRLEVTVKREGKIHRIVFAGGDVVEPLAQVG
                     KCAVKDSGTEVRVWPDGKYFESPNYSIPELERLLRAKAVLLPGVRVSLTRPVKGEDEA
                     HTQTWHYPDGLKSYLTDLIADAQEAVPLFSCENYISDEHNGDFSIGEGAAFALTWLEE
                     GSCANESYVNLIPTPLGGTHEAGLKQAVFNAVSNFINLHNLLPRGVKVQSDDVFGKTA
                     FVLSARVLDPQFQGQTKDKLTNRDALKLVATVSGDPLELWLNQNVDFGKKIAELAIRQ
                     AQARMRSVKKIEKKKGSGVAVLPGKLTDCESEDIRENELFLVEGDSAGGSAKLARDKA
                     TQAILPLRGKVLNSFEVHPDQLFGNAEIHDISVAIGVDPHGINDHPDLSGLRYGKIAI
                     LSDADVDGSHIQVLLLTLFYRHFPKLVADGHIYVAQPPLFRVDVNAQGKSKPARKFYA
                     LDQNELDSILERLQKEGVKETAYSISRFKGLGEMNPDQLKDTTMHPDTRRLLQVQIPE
                     GADDETRDIFVKLMGKGEAAARRAWMEREGDTAELDI"
     gene            complement(50577..50981)
                     /locus_tag="ACFOV4_000124"
     CDS             complement(50577..50981)
                     /locus_tag="ACFOV4_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="HFC7618223.1"
                     /translation="MTQETALGAALKSAVQTMSKKKQTEMIADHIYGKYDVFKRFKPL
                     ALGIDQDLIAALPQYDSALIARVLANHCRRPRYLKALARGGKRFDLNNRFKGEVTPEE
                     QAIAQNHPFVQQALQQQSAQAAAEAAGSSAAE"
     gene            complement(51073..52173)
                     /gene="aroC"
                     /locus_tag="ACFOV4_000125"
     CDS             complement(51073..52173)
                     /gene="aroC"
                     /locus_tag="ACFOV4_000125"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFC7618224.1"
                     /translation="MAGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFD
                     LDRRKPGTSRHVTQRREADQVEILSGVFEGKTTGTPIALLIRNTDQRSKDYGNIATSF
                     RPGHADYTYWHKYGTRDYRGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQV
                     GEKEIRFEGCEHISQNPFFAANHSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGL
                     GEPVFDRLDAEIAYAMMGINAVKGVEIGAGFGSVVQRGSEHGDELTPQGFLSNHSGGI
                     LGGISTGQDIHVNIAIKPTSSIATPRRSIDINGNPIELATHGRHDPCVGLRAAPIAEA
                     MLALVLIDHALRHRAQNADVQVNTPDITLSNK"
     gene            52316..53404
                     /gene="trmA"
                     /locus_tag="ACFOV4_000126"
     CDS             52316..53404
                     /gene="trmA"
                     /locus_tag="ACFOV4_000126"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030697 - tRNA
                     (uracil(54)-C5)-methyltransferase activity, S-adenosyl
                     methionine-dependent [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HFC7618225.1"
                     /translation="MSDYTQQLQDKKDHLKTLFAGLDVPEWEVYESPDKHYRMRAEFR
                     IWHEGGEMFYAMFEKGQKAGGASLIRCDRFDAASEAVNCLMPELIAVAAQSAELRNRW
                     YAVEFLSTLSGEMLVTMIYHKKLGDAWQQAAQALQQQLDISVIGRSRGQKIVLKQDYV
                     TETLKVGNRDFRYRQIEGSFTQPNAAVCQKMLEWACGAAEGLDGDLLELYCGNGNFTL
                     PLSEKFERVLATEISKTSVSAAQWNIEANRIGNIKIARLSAEEFTEAYTRKREFKRLK
                     DGGIALTDYAFSTIFVDPPRAGIDEQTLKLVSQFDNIIYISCNPETLRANLDTLVETH
                     AVERAALFDQFPFTPHIESSVLLKKKIL"
     gene            53425..54618
                     /locus_tag="ACFOV4_000127"
     CDS             53425..54618
                     /locus_tag="ACFOV4_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HFC7618226.1"
                     /translation="MYRHIEYYPGDPILSLVETFKNDPRPEKVNLSIGIYFDDEGKMP
                     VLESVSRAETARAAAPAPSPYLPMEGLDTYRSAVQHLLFGKDNPALAQGRIATVQTLG
                     GSGALKVGADFLHRWFPEARAYVSDPTWDNHRGIFEGAGFEVGTYPYYDPATVGVKFD
                     EMTAFFNTLPENSVLILHPCCHNPTGVDMSEQQWDEVLHIIKTRKLIPFMDIAYQGFG
                     GDLDSDAYAVRKAVEMELPLFVSNSFSKNLSLYGERVGGLSVVCPNKEEAELVFGQLK
                     FTVRRIYSSPPAHGAYIAADVMNSPELYALWQNEVYMMRDRIRAMRQKLYDVLTAQIP
                     DRDFAYFIKQRGMFGYTGLSVEQVRRLRDEFAVYLLDSGRMCVAGLNTSNTDYVARAF
                     AEVLK"
     gene            complement(54683..54758)
                     /locus_tag="ACFOV4_000128"
     tRNA            complement(54683..54758)
                     /locus_tag="ACFOV4_000128"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54723..54725),aa:Arg,seq:ccg)
     gene            55043..55882
                     /locus_tag="ACFOV4_000129"
     CDS             55043..55882
                     /locus_tag="ACFOV4_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HFC7618227.1"
                     /translation="MKQLRDNKAQGSALFTLVSGIVIVIAVLYFLIKLAGSGSFGDVD
                     ATTEAATQTRIQPVGQLTMGDGIPVGERQGEQIFGKICIQCHAADSNVPNAPKLEHNG
                     DWAPRIAQGFDTLFQHALNGFNAMPAKGGAADLTDQELKRAITYMANKSGGSFPNPDE
                     AAPADNAASGTASAPADSAAPAEAKAEDKGAAAPAVGVDGKKVFEATCQVCHGGSIPG
                     IPGIGKKDDWAPRIKKGKETLHKHALEGFNAMPAKGGNAGLSDDEVKAAVDYMANQSG
                     AKF"
     gene            complement(56344..59196)
                     /gene="gcvP"
                     /locus_tag="ACFOV4_000130"
     CDS             complement(56344..59196)
                     /gene="gcvP"
                     /locus_tag="ACFOV4_000130"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HFC7618228.1"
                     /translation="MKLSELFNPDEFAARHLSFGDEAALLAAVGEKSIDDFVGNTVPQ
                     SIRMPSELDLPDALTEADALAKLKGIASKNMINKSYIGLGYYPTRVPNVILRNVLENP
                     GWYTAYTPYQAEIAQGRLEALLNFQQVCIDLTGFPVAGASLLDEATAAAEAMAMAHRV
                     GKVKSERFFVDERVYPQTLDVMKTRAKYFGFELVVGDFAQADEGEYFGALFQYVGKDG
                     DVQDLQDVIGRLKAKGTIVAVSADIMSLVLLKPPAELGADIALGNTQRFGVPMGFGGP
                     HAAYFAFKDEFKRSAPGRIIGVSKDASGKPALRMALSTREQHIRREKATSNICTAQAL
                     LANLAGMYAVYHGPEGVKRIANRIHALASAFADALVSDGLNVVHKVFFDTVTIDFGSK
                     EKADQVFAAALASGYNLRRVNDTQVAAAFHETSAYEDLVDLYRAFTGKDTFTFADDVK
                     GRLNAELLRQDDILQHPVFNSYHTEHEMLRYLKKLEDRDLAMNRSMISLGSCTMKLNA
                     TAEMLPITWAEFTDIHPYAPEAQTAGYRELLADMENSLKAITGFDAISLQPNSGAQGE
                     YTGMLAIRRYQESQGEAHRNICLIPKSAHGTNPATAAMLGLKVVVVDTDEHGNVNIDD
                     LKAKAEQHRDALSAIMITYPSTHGVYEEGIRDICRIIHENGGQVYMDGANLNAQIGIM
                     QPAEVGADVLHMNLHKTFCIPHGGGGPGMGPIGLKAHLAPFAPGHTLTDTHNAAADQT
                     AVAAAAYGSASILPITWMYLTMMGKQGMEQATRWALLNANYVAKALGEDYPILYTGKN
                     GRVAHECIVDLRPLKAESGITETDIAKRLMDYGFHAPTVSFPVAGTLMIEPTESESKA
                     ELDRFIAALKQIKQEVLKVGRGEWPKDDNPLVNAPHTAADITGNWAHPYSREEAVFPL
                     PFVREHKFWPFVNRVDDVYGDRNLVCSCPPMENYED"
     gene            complement(59227..59586)
                     /locus_tag="ACFOV4_000131"
     CDS             complement(59227..59586)
                     /locus_tag="ACFOV4_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618229.1"
                     /translation="MTDRPSLLWIKPGQAEIMEYCEPEEASDPYATYRRANLMAGLPL
                     FVVILVLLNIVFPLPAHPLAWLVPAGFMVLGGGFPLSLPLVALLVLTCCILAHCPPLS
                     RLLCYPCPNHPMSKNSA"
     gene            59585..59764
                     /locus_tag="ACFOV4_000132"
     CDS             59585..59764
                     /locus_tag="ACFOV4_000132"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HFC7618230.1"
                     /translation="MPSEPAGRLFQKTPYRCNFMRLYGVGFALQTAYASRSSLVSQSV
                     HDYINNLGADKPLFI"
     gene            complement(59757..60398)
                     /locus_tag="ACFOV4_000133"
     CDS             complement(59757..60398)
                     /locus_tag="ACFOV4_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylesterase"
                     /protein_id="HFC7618231.1"
                     /translation="MPSEKPMNRRIFLLGAGALLLTACGRKSARTHAKIPEGSTVLAL
                     GDSLTFGYGANPGESYPAQLQKLTGWNIVNGGVSGDTSAQALSRLPALLARKPKLVLV
                     GIGGNDFLRKVPEEQTRANIAKIIETVQKENIPAVLVGVPHITLGALFGHLSDHPLYE
                     DLSEEYGIPLFGGAWAEILGDNNLKSDQIHANGKGYRKFAEDLNQFLRKQGFR"
     gene            complement(60388..60939)
                     /locus_tag="ACFOV4_000134"
     CDS             complement(60388..60939)
                     /locus_tag="ACFOV4_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFC7618232.1"
                     /translation="MNYCEFAASLPENTDNPNKHYHDTQYGFPIEDDNELFERLVLEI
                     NQAGLNWTLMLKKQQAFQTAFEGFDINTVAAFDDTDRERLLADAGIVRNRLKIDAAIF
                     NARQIQALQQEYGSFKNWLDAHHPRSKDEWVKLFKKHFKFVGGEIVGEFLMSTGYLKG
                     AHAESCPVYRKTLKYHPKWLDAV"
     gene            complement(60943..61461)
                     /locus_tag="ACFOV4_000135"
     CDS             complement(60943..61461)
                     /locus_tag="ACFOV4_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HFC7618233.1"
                     /translation="MRLFPIAAALTLAACGTMQSTQYFVLPDSRYIRPATQGGETAVE
                     VRLAEPLKRGGLVYQTDPYRLNTAQNHVWADTLDDMLEAALSNAFNRLDSARIFVPAS
                     RSGSTEKWTVYIDAFQGSYTGKTLISGYAVLPDGMNRPFHIETEQQGDGYAAMTAALE
                     QGLKQAAQQMVE"
     gene            complement(61461..63122)
                     /gene="pqiB"
                     /locus_tag="ACFOV4_000136"
     CDS             complement(61461..63122)
                     /gene="pqiB"
                     /locus_tag="ACFOV4_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HFC7618234.1"
                     /translation="MTDNSPPPNGHAQARVRKNNTFLSAVWLVPLIALIAGGWLWVKE
                     IRNRGPVVTLLMDSAEGIEVNNTVIKVLSIDVGRVTRIKLRDDQKGVEVTAQLNADVS
                     GLIRSDTQFWVVKPRIDQSGVTGLGTLLSGSYIAFTPGKSDEAKDVFQVQDIPPVTAI
                     GQSGLRLNLIGKNDRILNVNSPVLYENFMVGQVESAHFDPSDQSVHYTIFIQSPNDKL
                     IHSASRFWLESGINIETTGSGIKLNSAPLPALLSGAISFDSPKTKNSKNVKSEDSFTL
                     YDSRSEVANLPDDRSLYYTAFFKQSVRGLTVGSPVEYKGLNVGVVSDVPYFDRNDSLH
                     LFENGWIPVRIRIEPSRLEINADEQSKEHWKQQFQTALNKGLTATISSNNLLTGSKMI
                     ELNDQPSASPKLRPHTVYAGDTVIATRGGGLDDLQVKLADLLDKFDKLPLDKTVAELN
                     GSLTELKSTLKSANAALSSIDKLVGKPQTQNIPNELNQTLKELRQTLQGVSPQSPIYG
                     DVQNTLQSLDKTLKDVQPVINTLKEKPNALIFNSSSKDPIPKGSR"
     gene            complement(63115..64449)
                     /locus_tag="ACFOV4_000137"
     CDS             complement(63115..64449)
                     /locus_tag="ACFOV4_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqiA/YebS family transporter subunit"
                     /protein_id="HFC7618235.1"
                     /translation="MPPLIFATFPMKPFAENIPHSLRGNCRDEALPPHTVDCPECGCR
                     ADVPRLDRGEAAFCPRCGYKLFRVGRHPFSAPPAYAAASLILMAFAYGMTYIEVGIPG
                     AASVLSLPEMMRLMVFQDYGFLAEVMFVLTFGAPVLFLLLCLYVYAALIRKRVYPALR
                     LATRVMVRLRQAMMVDVFFVSTLVAYIKLSSVAEVRFGPAFYLMFALSVMLIRTSVSV
                     PQHWVYFQIGRLTGDNAVQTVTEDKICCSRCLYFRDKDEQPCGVCGADLYRRRPKSLS
                     ISLAFLVAAFILYFPTNILPIMISSNPTALEINTIFNGIVYMWDDGDRLIAVIIFSAS
                     IMVPVLKIIAMAVLIYSAYFKPVMSADKMSVLYRITESIGRWSMIDIFVIIILMCSFH
                     TYAARVIPGSAAVYFCLVVILTMLSAYYFDPRLLWDKRASDGIAFNETEKYD"
     gene            64793..65422
                     /locus_tag="ACFOV4_000138"
     CDS             64793..65422
                     /locus_tag="ACFOV4_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biliverdin-producing heme oxygenase"
                     /protein_id="HFC7618236.1"
                     /translation="MSETENQALTFAKRLKADTTAVHDSVDNLVMSVQPFVSKENYIK
                     FLKLQSVFHKAVDHIYKDAELNKAIPELEYMARYDAVTQDLADLGDKPYEYGKPLPHE
                     TGNKAIGWLYCAEGSNLGAAFLFKHAQKLDYNGEHGARHLAPHPDGRGKHWRAFVEHL
                     NALNLTPEAEAEAIQGAREAFAFYKVVLRETFGLAADAEAPEGMMPHRH"
     gene            65616..66224
                     /locus_tag="ACFOV4_000139"
     CDS             65616..66224
                     /locus_tag="ACFOV4_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="HFC7618237.1"
                     /translation="MSNSSFKLSALAIACGLALSACSSGGGDAPSVKPTPTVPGASNP
                     APANPEPSAPAASPLKTGELGEKYFYGEGEITKLVINGETINLTVADEQLSRRVKLWT
                     DFDKIITSQGFENLIYGAAKLADGSYALFVQGKLSDSLPGDTVTYSGDVLHFRSRNLT
                     EGNWFNEGNSFRAAGSFTATVNFAGKSLNGKINSGDGLYMGT"
     gene            66240..66425
                     /locus_tag="ACFOV4_000140"
                     /pseudo
     CDS             66240..66425
                     /locus_tag="ACFOV4_000140"
                     /inference="COORDINATES: protein motif:HMM:NF013466.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
     gene            complement(66755..67231)
                     /locus_tag="ACFOV4_000141"
     CDS             complement(66755..67231)
                     /locus_tag="ACFOV4_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease"
                     /protein_id="HFC7618238.1"
                     /translation="MLAACQSGSAPKNAHTASPGTPAGESCKVIRGDTAGSGKNIIYR
                     CCNGQAAINAAIADGVLESGIPVSFGGGGVPVANGRNLVTRQAANGIGKSDSEAYERA
                     LINAARKFQQTAGKLGGRGVTGFHSYFDKQPLQGGQYDCQAGSFHVRVVMRANVVR"
     gene            complement(67365..68720)
                     /gene="yegQ"
                     /locus_tag="ACFOV4_000142"
     CDS             complement(67365..68720)
                     /gene="yegQ"
                     /locus_tag="ACFOV4_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HFC7618239.1"
                     /translation="MKAPELLLPAGGLERMRAAYDYGADAVYAGSPRYSLRARNNEFA
                     KLDVLEQGIKEAHERNKKFFLTVNTLPHNSKLKTFVSDMEPLIAMKPDALIMADPGLI
                     MTVREKWPEMPIHLSVQANTTNYWGVKFWQNIGVERIILSRELSMEEIAEIRQQCPDI
                     ELEVFIHGALCIAYSGRCLLSGYFNHRDPNQGTCTNSCRWDYKVHNATESDAGDAQLL
                     QGFNFEKAQEEANQNFEGINGQKRHPYADKVFLIEESNRPGEMMPIMEDEHGTYIMNS
                     KDLRSIEVVEKLAKIGVDSLKVEGRTKSLYYVARVAQSYRKAIDDAVAGRPFDYSLLS
                     ELEGLANRGYTSGFLERHQTQDYQNYLTGHSIAKQSQYVGHVTEIDAEGWATVEVKNR
                     FAIGDSLEIIHPSGNQTIKLEQMARKGQPVDVAPGNGIQVKIPNMRGKEKALIARVLN
                     P"
     gene            69045..69833
                     /locus_tag="ACFOV4_000143"
     CDS             69045..69833
                     /locus_tag="ACFOV4_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFC7618240.1"
                     /translation="MNPKIVFFDIDDTLYRKYTDTLRPSVKTAVAALRGKGILTALAT
                     GRSLATIPEKVRDMMAETGMDAVVTINGQFALLHGKTVREVPMDAGLMGRVCAHLDGL
                     GMDYAFVGGEGIAVSALSECVCRALQHIASDFFADKDYFSSKPVYQMLVFAEENEMPP
                     WSDIVEREGLKTVRWHEEAVDLLPAGMSKTDGIRSVVGALGLEMADVMAFGDGLNDVE
                     MLSEVGFGVAMGNGEQAAKEAAKYVCPSVDEDGVLRGLQDLGVI"
     gene            complement(69879..70478)
                     /locus_tag="ACFOV4_000144"
     CDS             complement(69879..70478)
                     /locus_tag="ACFOV4_000144"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFC7618241.1"
                     /translation="MALKTSNLEHAMLVHPEAMSVGALADKIRKIENWPQKGILFHDI
                     TPVLQSAEYFQLLVDLLVYRYMDQKIDIVAGLDARGFIIGAALAYQLNVGFVPIRKKG
                     KLPFETVSQSYALEYGEAAVEIHTDAVKPGSRVLLVDDLVATGGTMLAGLELIRKLGG
                     EIVEAAAILEFTDLQGGKNIRASGAPLFTLLQNEGCMKG"
     gene            70606..71223
                     /gene="gmk"
                     /locus_tag="ACFOV4_000145"
     CDS             70606..71223
                     /gene="gmk"
                     /locus_tag="ACFOV4_000145"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFC7618242.1"
                     /translation="MSAYRKGNIFIISAASGTGKTTLVSRLLANHNGLRVSVSHTTRP
                     PREGEVNGVHYHFVSKEEFESLIAQEAFLEYADVFGNYYGTSAEGVNALAAAGYDVIL
                     EIDVQGAAQVRNALPEAVGIFILPPSFDVLAARLNGRGTDSREVIQRRLSKARHEIEQ
                     SVLFDFVVVNDDLARAEEDLRHIVNACRLKRSRQLGFIADLLENS"
     gene            71282..71488
                     /gene="rpoZ"
                     /locus_tag="ACFOV4_000146"
     CDS             71282..71488
                     /gene="rpoZ"
                     /locus_tag="ACFOV4_000146"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFC7618243.1"
                     /translation="MARITTEDCTGKISNHFDLTLVAARRARQLENGNTPLVDDVRNN
                     KPTVTALREIAAGHIGTELLTRNK"
     gene            71581..73737
                     /locus_tag="ACFOV4_000147"
     CDS             71581..73737
                     /locus_tag="ACFOV4_000147"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFC7618244.1"
                     /translation="MPVPQPTAPYDPLTAEARALLFHTASYLKPEEQAELEKAVAYAF
                     RAHDGQTRKSGEPYITHPIAVATQLALWHMDIQGLCAGVMHDVLEDTGVTKGEMAAVF
                     GNTVAEMVDGLSKLEKLKFEDHAEHQAESFRKLILAMTKDVRVIVVKLADRLHNMRTL
                     GSMRPDKRRRIARETLEIYAQIANRIGLNNAYQELQDLSFQNLHPNRYETLKKAMDKS
                     RKNRQDVVGKVLRAFGQRLVGANIEAKIKGREKNLYGIHQKMMAKKLRFAEVMDIYGF
                     RVIVNSIPACYAALGALHTLYQPKPGRFKDYIAIPKSNGYQSLHTTLVGPYGLPIEVQ
                     IRTKEMDAVAEGGIAGHWSYKSYSKTVDQAVLHTNRWLKNILDLQASSANAIEFLEHV
                     KVDLFPNEIYILTPKGKILTLPKGATPVDFAYAVHTDIGHKTVAARINNIMMPLRTKL
                     KTGDSVEIITSEHAKPNPAWLNFAVSGRARSAIRQYIKNLNRHDAVVLGENLLQKALS
                     SLLPKDVLLSDGIKEKYLADLNDKQTSFEEVLYNVGMGHTLPVYVAMHIAELAGKHFG
                     SEVRLSSIKVDGQESGHIHFAECCHPVPGDSIRLLLVKGKGMIIHRDTCPTLLKSDPE
                     QQLDADWENMNGQNYRVGLQVQSEDSHGLLALMAQAISDSGADIESVETPSKSQSGTE
                     GFVEFKFLLKVKNLNQLNQIIQNLHSIPYIRKVIRS"
     gene            complement(73804..74988)
                     /gene="coaBC"
                     /locus_tag="ACFOV4_000148"
     CDS             complement(73804..74988)
                     /gene="coaBC"
                     /locus_tag="ACFOV4_000148"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HFC7618245.1"
                     /translation="MGKHILLGVTGSIAAYKSCELVRLLKKQGHSVTVVMSRSATEFV
                     SPLTFQALSGNPVLTDTHGGNGSNGMEHINLTRNADVFLIAPASMNTVAKICNGVADN
                     LLTSLAAARKCPLAIAPAMNVEMWLNPANQRNIAQLVSDGITVYMPGLGEQACGENGM
                     GRMPEPAELLDLLPDLWTPKILRGKKILITAGATFETIDPVRGITNTSSGKMGVALAR
                     ACRAAGAEVSLIHGQLQTALPFGISDTVQAVSAEDMHRAVHRLIEKQDAFISVAAVSD
                     YKVKNKSTQKFKKDKNAKPLSIELDENPDILASIASLPNPPFCIGFAAETENVMAYAR
                     EKRIKKKIPVIVANDVSIAMGKPTNRITIIGDDGELSFPETSKDEAAMQIVERLAGYL
                     NK"
BASE COUNT        17719 a        18723 c        20623 g        18005 t
ORIGIN      
        1 gcaaaggtct cccactgtaa aaacggagaa ggacagagga cggcagtaag gtttgccgtc
       61 ctctttttca agttgcggtg gaatgccgct tgaaggtgtg gtttaaacgt ttcggcttgt
      121 aatcagacgc gggcgttgtc cagccgctct ctgaagtttt ccaaatttac gcctgccgct
      181 tgggcgcggc ggatgatttc gtcaaccggc ataccttctg ccgcccggcg gaagccccac
      241 aggagggagc agcgcgtacc ggtccggcaa taggcaagga cgggatattc ggcttgtccg
      301 atgagttggc ggaaggtttc gacatcgtgt ttttggatgt cgcgtgcggt aacgggttgg
      361 tgatggaatc cagtaacgcc tgcttgttcc agccactgtt tgatttgggc gaagtcgggt
      421 tgcgattctt cttcgcggtc ggggcggttg cagatgacgg ttttgatgcc cagttgcgcg
      481 atttgttccg catcggcttt ggtcagttgc ggagaaatat agaggtgttc gtcaagtttc
      541 agaatggcca ttttgtttcc tttactttgc ggttgttttt cagacggcat tttgtgtgca
      601 atgccgtctg aaagtttaac cgaacaacca gttgtccaac aggttccggt ctgtgatatg
      661 taggatggca gtatccgctg ccgctgcctg aaccgtcaag acggtttgac gcaatatgcc
      721 ggcacggaag aagtggatat tgatttttgc attgacgtgg tatcgggccc attgtgcggt
      781 aaagtcggtg caggcataac cgtctaaagc aatgattttg tcttgcgggc acagtgccgc
      841 agattccgcg ctgccgccgt tgaagacatg ggtcaggacg atgtggtcgg tgttttgttt
      901 gaaacgtgcg ccaaaatcgc ctgccgacgg gacggggcag atgtgttctg cgtatccgcc
      961 gccgtgttgt cggggaagcg gcaggaaggt cagtcccacg cctgcggttg ccaggcattc
     1021 ggcaagcggc aaatcttcgg tactgtataa cgctttttgg aaaaaatctt ccaaatccaa
     1081 gccggtaatt tcctgacagc ggatttgcca gtgtttttcc ggaatacccg agtgtgtgtc
     1141 cctccactcc cgatagagtt tgtccattaa cgtatcgaga gaatgtctgc cgttgcttcg
     1201 gttgcgtatt atcagatcaa ggcacaatgc ggcaagcgcg cctttctggt agtagctgac
     1261 gatggcgttg gggctgtttt catccggttt gtaaaatttg ttccacgcgg taaaactcga
     1321 ttccgccaag gtctgcctca aacggccgcg ggtttgttgt acgcgcgtaa tgccttgtgc
     1381 cagcaggttt aaataagatt cgggcgagat ggtgcggctg cgtgccaaaa acaaatcgtc
     1441 gtaataggat gtaatacctt cgaatgccca tagttgttcg gtatagtttt ctttgtcgag
     1501 gtcataaggg acgaacgcgg caggtttgat ggatttgacg ttccacgcgt gaaaatattc
     1561 gtgggagaaa agtccgagca atgtggtgta ggtatcgtcg gcatcggtca taccgtacgg
     1621 cggaaggctg tggcggtcgg cgagcagggc ggtgctgtcg gtgtgttcca aaccgccgta
     1681 aatatggtcg ccgacgtgga gcaggaacaa atatttttga aacggggcag gggaggaaaa
     1741 caccgccagt tctgtttcgc agattttttt gatatccgaa accagcctgt tgcggtcgaa
     1801 atcgggatat atgccgctta aggcaattgt gtgcggaatg cctgccgcct caaaatctaa
     1861 aaattcaatc aagcccatct cgacaggtcg gtcaatcaat tcggcataag atgccgcctg
     1921 aaagacaaac ctccctgttt ccggcagcgt tgtggcaata cgccattcgg acggaatacc
     1981 cgtcaattcc aagcggtgcg gcagcgtttc cgttccttcg actttcaaaa acaggcacga
     2041 tccgtcaaaa aaaccgcgtt ctgtcgtcag gaaagaacct cgaaccgaca aatcgaatgc
     2101 atatacggtg tagcggattt gccactcgcc gcgtacggcg gcggcatgcc agcggttttt
     2161 ggcaatttgt tcgagcggca tggacgtgcc gttacaggat gcatggatag aagtgatgtg
     2221 gcgggaaaaa tcccgaatca gatagctgcc cggaacccag tttggcaggc ttatttctat
     2281 aggaagatca tcatcttgtg tgaatgtcag caggatgtgc cactcgtggt cgagagggga
     2341 cggggttatt ttataatgaa tcataactat caaatatatc gttaaacggg atggattaaa
     2401 tacctttaaa atgcagctta acctacatca ataaagtgcc acaaaaaggg aaaattggaa
     2461 acaaaagcaa tggcggtcgg gttgtaattt attataacaa tatgatttat atgtaataaa
     2521 aaacagatta agcaaagggc tcgtcggcgg cgcgaatgta attccgcttg gcgtaataag
     2581 gcagatatgt taaatttaga aaaaattacg cttgcccgga ttgcacctta aacaggctgc
     2641 ggaagcggca ggataaaaat ctttattccc ataaattcat ggagactctc atggacacac
     2701 aaacttacaa ctacaaagtg gtgcgccagt tcgccatcat gactgtagtt tgggggattg
     2761 tgggtatgtt ggtcggcgtt atcgtcgccg cccagctttt tgctcctgcc ctcgacttgt
     2821 ctaatatcgg accttggttc cacttcggcc gcctgcgtcc gctgcacacc aatgcggtta
     2881 ttttcgcatt tggcggttgc ggcctgatcg gcacatcata ctacgttgtc caacgtactt
     2941 gtaatacccg tcttttcggc ggttggctgc cggcatttac cttttggggc tggcaggcgg
     3001 taatcgttgc cgccgtcgtc agcttcccta tgggttggac ccaaggtaag gaatatgccg
     3061 aactggaatg gccgatcgat attctgatta ctttggtttg ggtggcttac gccatcgtat
     3121 tcttcggtac gattgccaaa cgtaagatta aacatattta cgttgccaac tggttctacg
     3181 gcggctttat tttggcggtc gcacttttac acatcgtcaa caatatcagc atcccggccg
     3241 gtttgatgaa gtcatacccc gtctattccg gtgcgattga tgctatggtt caatggtggt
     3301 acgggcataa tgccgtgggc ttcttcctga ctgccggctt cttgggtatg atgtactatt
     3361 tcgtacccaa acaagcagcc cgccccgttt actcctaccg cctgtccgtc gttcacttct
     3421 gggcgttgat tttcacctat atgtgggcgg gtccgcacca tcttcactac actgcgctgc
     3481 ctgactggac gcaatctttg ggtatgattc tgtctttgat tctgttcgca ccctcttggg
     3541 gcggtatgat taacggcatc atgaccttgt ccggcgcgtg ggacaaactg cgtacagacc
     3601 cgattcttaa attcctgatt gtatccttgt ccttctacgg tatgtctacc tttgaaggcc
     3661 cgatgatgtc gattaaaacg gtcaatgcat tgagccacta tacggactgg accgtcgcgc
     3721 acgttcatgc gggtgcgttg ggctgggtag gctttgtaac catcggttcc gtctattaca
     3781 tgattccccg tctgttcggc aaagaacaga tgcacagcac caagctggta gaagcacatt
     3841 tttggattgc gaccatcggc gtggttctgt atatcgctgc catgtggatt gccggtgtga
     3901 tgcagggttt gatgtggagt tctttgaacg atgacggtac gctgacctac tcgtttgtcg
     3961 aatccgtaaa acgcaccatg ccttactacg tgatccgttt tgcaggtggt ttattgtatc
     4021 tgagtggtat gtgcattatg gcgtacaacg tgtaccgcac agccatcggt ggtaaagcag
     4081 tcgatgccga aatccctgcg gtttcccaaa cacagcacca ctaaaatact aagaaagata
     4141 ggctaccaaa atgaaattac aacaattggc tgaagaaaaa atcggcgttc tgattgtgtt
     4201 cacgctgctt gtagtcagtg tcggtctgtt gattgaagtt gtgcccttgg cctttaccaa
     4261 ggcggcaaca cagccggcac cgggcgtgaa gccttacaat gccttgcagg ttgccggacg
     4321 cgatatttac atccgtgagg gctgttacaa ctgccactct caaatgattc gtccgttccg
     4381 tgcggaaacc gagcgttacg gtcattactc tgttgccgga gagtcggttt acgaccatcc
     4441 tttccaatgg ggttccaaac gtaccggtcc tgatttggca cgtgtaggcg gccgctattc
     4501 cgacgaatgg caccgtatcc acctgctgaa tccccgtgat gtcgtgcctg agtccaatat
     4561 gccggcattc ccatggcttg cacgcaataa agtcgatgtc gatgcaaccg ttgccaacat
     4621 gaaggctttg cgtaaagtag gtactcctta cagtgatgag gaaattgcga aagcgcctga
     4681 ggctttggca aacaaatccg agctggatgc tgtagtcgcc tatctgcaag gattgggtct
     4741 ggctttgaaa aacgtaaggt aacatcatgg atattaacgg tattcgcgct cttttcacgg
     4801 tatggatctt tatctgtttc ctgttggtac tctatatcgt cttcaacagg cggaataaga
     4861 aaaactacga taatgccgca aacagcattt ttgatgaaaa ccaagatgcg caagataaga
     4921 aaagcgaaaa ccgttaatat tgtgataacg gagcaaaaca atgaacacaa catcccaatt
     4981 taccagtaat ttctggaata tatatattgc agttattgtc ttactgagct ttatcgcttt
     5041 ggcttggctg ctgctgtctc aaaatgttgt caaacgtccg aagaagggcg aagaagtaca
     5101 aactacgggt catgagtggg acggcattgc cgaatacgac aatccgctgc cccgctggtg
     5161 gttttggctg tgtgttttga cgtggctgtt cggtatcggt tatttggtta tgtatccggg
     5221 tgtcggcgac tacaaaggtc tgctgaaatg gaccagccat aaccaatatg aaaaagaggt
     5281 caaaaaagcc gatgagcaat acggcaaact gtatgccaag tttgcggata tgccgattga
     5341 aaaagtggca aaagaccctc aagccaagca aatcgcccaa aacctgttta acacttattg
     5401 tatccagtgc cacggctctg atgctaaagg ctctaaaggt tttccgaatc tgaccgatag
     5461 cgattggttg tggggcggtg atcccgataa aatccacgag accatcgaaa aaggccgtgt
     5521 tgcgactatg cctgcctggg gtcctgcttt gggcgaagaa ggcgtgaaag acgttgccca
     5581 ttatgtgatg tccctttcaa aacccgaagg tcagtatgat gaggaacgtg ccgcgcgcgg
     5641 acaagccttg ttcagcggtc cgcctgccaa ctgtttcact tgccacggcg ataagggaca
     5701 aggtatccaa ggtttgggtc cgaacctgac tgatgacgtg tggttgtggg gcggtacgca
     5761 aaaatccatt atcgaaacca ttaccaacgg tcgcagcagc caaatgcccg cttggggaca
     5821 tttcttggat aaagacaaac tgcatattat gactgcttat gtatggggtc tttccgataa
     5881 agacggtaaa gctccggtga aaaaagccga gcctgcaccg actcccgcac cggcggcaga
     5941 acccgcagcc tctgctcctg cagaagcagc acaagccgcg tccgaagcca aacctgccgc
     6001 agcagaacct aaagccgagg aaaaagctgc acctgctgcc aaagcggacg gcaaataggt
     6061 ttatgaaacc gtttgtgccg cctgccatgg caatgcgatt ccgggtattc cccatgtagg
     6121 catcaaagcc gattgggccg accgcatcaa aaaaggcaag gacacgttgc acaaacacgc
     6181 gatcgaaggt ttcaatacga tgcccgcaaa aggcggtcgc ggcgatttga gcgatgatga
     6241 ggttaaagct gcggttgact atatggtcaa ccagtcaggc ggcaaattct aacttgactg
     6301 agtttccgat attatcggtt atgaaaatcc agattcagta ttgaatctgg attttttgtt
     6361 ttaacgggca tccggtttta aacgcagact gcctatttgt tgtaatgaat tttgacttta
     6421 gtcataaaga attagtcttt attgtttata atcgcgcatc atcacgatag ccctattttc
     6481 aaaaggacga ttaatggata cacaaatcaa aactgaagcc gacaatcaga gcaaccggcg
     6541 ttatctgacc gtttggcggt ggcattttta tgccggtctg ctggttatgc cttttcttac
     6601 cctgcttgcc gttacgggtt tgggtatgct gctgtttgcc aatattaccg gtaaggaggg
     6661 cgagcggatt catgttgtgc cgcaggcaac ggtacaacct ctgtctgttc aggcggaagc
     6721 ggcacgcagt gccgttaatc cggaaacttc gtccgtcgtt cagtatattg cgccgcgtgc
     6781 cgatgatatg gttgccgtgt tccgtgtcaa caatgagggc aaggcaacga tggtcgcggt
     6841 cgatccttat acggcaaaag tggtcagtac catgccgcgc aatcagggtt ggtattacac
     6901 gatggatgaa atccacagcg atatgatgct cggtgcggca ggcgattatc ttttggaaac
     6961 ggcagcatcg ctgacgatta tcatgataat cagcggcttg tacctttggt gggtgaaacg
     7021 gcgcggcatc aaggcgatgc tgctgccgtc aaaaggcagg gcgcgttctt ggtggcggaa
     7081 tctgcacggc acgtttggaa cttgggtgtc gttgattttg ctgttgttct gcctgtcggg
     7141 tattgcttgg gcgggtattt ggggcggcaa gttcgtacag gcttggagtc agttccctgc
     7201 cggtaaatgg ggtgtcgaac cgaaccccgt ttcagtcgtg ccgacccacg gcgaggtatt
     7261 gaatgacggc aaggttaagg aagtgccgtg gattttggag cttacgccta tgcctgtttc
     7321 agggacgact gtgggcaaag acggcattaa ccccgacgag ccgatgacat tggaaaccgt
     7381 cgaccgtttt gcgcgggaaa tcggtttcaa agggcgttat cagttgaatt tgcccaaagg
     7441 cgaggacggc gtatggactt tgtcgcaaga ctctatgagt tacgatatga ttagtccgtt
     7501 tgccgaccgc acggtgcata tcgaccagta cagcggcaag attcttgccg acatccgttt
     7561 tgatgattac aacccgttcg gcaaatttat ggcggcgagc attgcgctgc atatggggac
     7621 tttgggctgg tggagcgtgt tggcgaacgt cgtgttctgc cttgccgtca tttttatcgg
     7681 tatcagcggc tgcgtgatgt ggtggaaacg ccgtccgtcc ggagcggcgg gcatggttcc
     7741 gccggcacaa aaaatcaagc tgccggtttg gtggatgatg gcattgccgc tattggcaat
     7801 cgcattgatc ttcccaaccg cactgcttgc cattgccgtg atttggctgc tggatacctt
     7861 gctgctgtcg cggattcctg ttttgaggaa atggtttaaa tgaccaaatg ccgtctgaaa
     7921 ggttcagacg gcattttgtt tgaaggcagg cgggggaaag gctatataat cccgaatact
     7981 tttccgcaac ttttgtcgaa atcatgtttt atctgtatca atccaaccgt cttgaaacgc
     8041 tggcggcact gtttgcccac attcaaaaag tcaaaccgct gaaatcggct ttacagcccg
     8101 aacagattat tgtgcagagt caggggatgc gccgctacct caacacctgc ctcgcccgcg
     8161 atttgggcgt ggcggcgaat ttggcgttca gcctgcccgc cagcctgacg tggaagctga
     8221 tgaaaaaact gattcccggc attccggaac tcagcccgtt tgcacccgaa gtcatgcgct
     8281 ggcggctgct ggatttgttc cgcagcgaag cattccggaa tacggcagaa tttgaagatg
     8341 tgaggaatgt gctgcaagac tatctaggca gcggcgaatc ggcagattac cagcttgcgg
     8401 gacagcttgc ggacatattc gaccaatacc ttgtctatcg tccgcagtgg atagacgcgt
     8461 ggcagcaggg caggatactc ggtttgggcg acgacgaaat ctggcagtcc aaactgtggc
     8521 gttacctcga cgatggcagg cagagcgcgc cgcaccgtgt cgcgttgtgg gaaaagctgc
     8581 ttgccgcgtt ggacaaggat aagctgcccg agcgttattt cgtgttcggc atttccacga
     8641 tggcgccgat gtatcttcag cttttgcaca agctgtccga acattgcgat gtgttcgtgt
     8701 tcgcactcaa tccgagcggg atgtattggg gcaacgtcat cgaagcggcg caaatcctca
     8761 aaggcggcgg cgatcccgat ttaactcagg cagggcatcc gctgctcgcc tcattgggca
     8821 agcaggggcg cgactttttc gactttttga acgaaatgga aatagaaggc gaaacgccgg
     8881 tatttgaaga aggcggacgc gatacgcttt tgcacgccct gcaaaccgat attcaaaacc
     8941 tgaaaatgcc gtctgaaaat gtgggaagcg tcaacacggg cgacggctcg atacgcatcg
     9001 tctccgcaca cagccccttg cgcgaattgc agatactcaa agacaaactg ttgaaaattc
     9061 tgcatgaaca tcccgattgg cagccgcatg atatcgccgt attaaccccg aacatcgaat
     9121 cctatacgcc ttttatcgaa gccgtgttcg gacaggcgca gcccggtgcg caggcattgc
     9181 cgtattccgt ttcagacgtg aaaatcagcc gccgacaacc gctgtttcat gctttgtcat
     9241 gcctgttcga cttgttggaa agccgatttg aagtcgataa agtgcttgtg cttttagaaa
     9301 ccgcacccgt gttgcgccgt ttcggactga ctgaggacga tttgccgctt ttgcacgata
     9361 tggttgccga tttgaacgtt cactggggtt tggacggaga aatgcgcggc ggcacggatc
     9421 agctgttcac ctggaagcag gcggtagaac gcatgatatt gggctggatg ctgcccgaag
     9481 gcggcaaccc gatgtggcag gatgtcagcg cgtggtatgc cgacgtgaat caaaccgccc
     9541 tgttcggacg ttttgccgcc ctcctcgaaa ccctgtcgga tattgtacgg atatggcggc
     9601 agcccgcaac gatcggcgaa tgggtggcgc gttgccggga tttgcttgaa acattgttcc
     9661 aagctgaagc cgatgaccaa aagtcagtcc aaaaccttga aaacgaatgg gtcaaatggc
     9721 aggcggaaac agaattggcg caattttccg gacagttgcc gcaacaaacc gtcatccgcc
     9781 atatccgacg tttcctcgac agtgaaagcg aggcaggctt tttacgcggc ggcatcacct
     9841 tttgcagtat ggtgccgatg cggagcctgc cgttcaaagt catctgcctg ttgggtttga
     9901 acgacggaga ttttccccgc aataccaaag ccgccgtatt cgacctgatt gccaaacatc
     9961 ccgccaaagg cgaccgcgcc cgccgcgatg acgaccgcta cctcttcctc gaagccctca
    10021 tcagcgcgcg cgaaatcctc tacctgtcct acatcgggcg cgacatccgc aaagacgaag
    10081 agcttgctcc gtcttcgctg ttgggcgaac tcatcgacac agttgccgct atggcgggca
    10141 tcggtagccg ccaacttgca caaaactgga tagaacagca tccgctgcaa gccttctcgc
    10201 gccgatattt tcaagaaggc ggacgttcag acggcatatt cggcacgcgt accgactacg
    10261 ccaccgcgct cggacaaacg cccgaaccgc cgcaaccctt tttcgaccaa cccgtagaaa
    10321 acgccgaacc tgttgccgaa atcggacagg acgaatttat ccgtttctgg cgcaaccccg
    10381 tcaaagtatg gcttcagcag cagcttgcgt ggagcgaacc ccatatcggc gaagcctggg
    10441 agcctgccga acccttcgag ccgcaacacg ccgatcaaat cgccgaaacc tacatcgaag
    10501 cacggcgcga aggacgggat tttgcccaaa ccgccgcccg catcggggcg gaaagcctcc
    10561 tgccgtcggg agagttgggc agactttggc agcagaactt ccaaactgct gccaaacaaa
    10621 tcgacacggc ggttttaaac agccccaaac tgccaccgct ttcatatgcc ataccgtcgg
    10681 acgggcaaat cctgaaaggc agcttgggca atctgtaccg ctgcggacaa gtgttttacg
    10741 cctacggcaa acccaacgcg ccgcaacgta tcgcttttct gctggaacac ctgatatttt
    10801 gcgccgttat gccgtctgaa gccgaaatgc ggcaaacctt tatcgtccaa tccggagaaa
    10861 ccgaaatatt ggcggaaatc gcgcaagaca gggcattgca gctattgtcg gaatggatgg
    10921 cgtttttcaa tatcgggcaa aaccgcccgc tgccgttttt tgccaaaacc tcgcttgcca
    10981 ccgccgaagc gtttgcccaa aaacaagatt gggaagccgc cctgaaaaaa gcccaaaccg
    11041 cctaccacgg cagcaaagtc agcaaagggc agaaagacta taccgaagtc gccctcgtgt
    11101 tcggcaacgc aagccaaaac ccgctcgaac agcccctgtt tgaaaacctc gtccgtctgc
    11161 ttgccgacac gcttgccgca gcggaaaaaa aggaagagac cggagaagcc tgacgggata
    11221 gaaaggcaaa tgccgtctga aagcgtttaa gcatttcaga cggcattttg tttatcgtgt
    11281 ttaaggtgcg ggatacaaag tgggtgcgcc gggaccgacg ggcagaccca aaacaaatac
    11341 ccaaatgcag aataaggcaa tccacgcaat caagaagaaa gcggaatacg gcaacatcat
    11401 agaaatcagc gtacccacgc ccgcatcttt tttgtatttg atcaccgtcg ccataatcag
    11461 cccgaaataa ctcatcatcg gcgtaataat attggtaacg gaatcaccga tgcggtaagc
    11521 ggcttgaatg acttcgggcg cgtagccggc caacatcagc atagggacga aaatcggcgc
    11581 agttaccgcc cattgcgcgg aggcggagcc tatcatcaga ttgataaaag cacaaattaa
    11641 aataaaaccg ataaacaaca cgctgccgcc caagccgact tcttttaaga acgtcgcccc
    11701 tttaacggca atatattgcc caatattcgt ccaattaaaa aatgcgacaa actgtgcggc
    11761 aaaaaagatg atgaccaaat aaagccccag agtactcatc gattcggcca tcgcattaac
    11821 gacttcctgt tcgccgcgca aacttcgggt tacccggcca taaacaatgc ccggcagcgc
    11881 aaacaacaag aaaataaaaa caacaatcga ttttaaaaac ggcgaaccgg aaaccaatcc
    11941 tgtttcagga tgacgcaaaa taccgtcggc agggacgatg ctccaagcca atagggcgga
    12001 taaggcaaca aacaccacgc cagcccaaat taatccttta tattccaaag gcgtgatttc
    12061 attggaatgc cgaatgtctt tttcttcttg tgacaaatct gattgataag ggcccaattg
    12121 cggttcgacg attttttcag taacaaaata accaatcaaa gcaatcacaa acgtactggc
    12181 taccataaaa aaccagttgg cttcagggcc tacgacgtag tcgggatgga tgatttgcgc
    12241 cgcctgttgg gtgatgcctg ccaagagcgg atcgattgtg cctaagaaca gattggccga
    12301 ataaccgccc gaaacgccgg cgaaagccgc agccagaccg gcaagcggat ggcggccgag
    12361 ggaatgaaag atgatggcgg acaaagggat taggacgaca tagcccaatt cagaagcggt
    12421 attagataaa atccctgtaa aaacaaccat aaaagtagtg agtttgcgtg gagattttgt
    12481 gagcaataag cgcattaatg cggaaatcaa gcccgatttt tccgcaatcc ccacgcccaa
    12541 taaagaaacc aacaccgttc ccaacggcgc gaaaccggtg aaatttttaa cggtatgcgt
    12601 caggattttg atcaaaccgt cagcatcgag caggctgaca acgtgaatca aaccgtcatc
    12661 ggcacgtcct ttcgcaccaa cagggcgcgg atcggggacg gatagtccga aatacgcacc
    12721 ggcggcagag gcaatcagca ataacacaat gaaaataata aaaagcgtaa ccgggtgcgg
    12781 caacatattg cccagccatt cgactgtgcg taaaaatcgt ccgtcccgtt gcgtatcggt
    12841 ttgactcatc tgcttctcct taaaaaaaat atattgagtg cattaaattt ttgaatgtaa
    12901 catgaagtgt tttgtaagca aactaaaata atcgtatatg tatataaccg taatagatta
    12961 aaacagaaaa tgcccacatc gttattctca taaaggcggt aatccgaaaa cttgacgtta
    13021 aagccttatc aggaatgact ggaactcaac aaagcggttt cccgctttcg cggaaatggc
    13081 gggattttcg gtttttgttt gcaaaaatgc cggagaaaaa tgcagtttac attttgaatg
    13141 gtattgttat taattgtaaa taaatattgg aaggtaaatg atatgaaaaa tgaaattcaa
    13201 aaaattatgg acaaatatga tccatggcat gaagatgatt ttgagtcgta tgaagacatt
    13261 gccaaagatg tatcgttgat gacagataaa acgttcattg aacattattt gttagaagtt
    13321 tattcagaag aaaacggaca ttttgaccaa gagaatgtcc atgcaatgat agaagaaatt
    13381 aaaaatgcaa tttagtgaat atgagacctt tgcaaaaata gtctgttaac gaaatttgac
    13441 gcataaaaat gcgccaaaaa attttcaatt gcctaaaacc ttcctaatat tgagcaaaaa
    13501 gtaggaaaaa tcagaaaagt tttgcatttt gaaaatgaga ttgagcataa aattttagta
    13561 acctatgtta ttgcaaaggt ctcaatatgt atttttagaa gaaggctttg tgtcattttg
    13621 atgccgtctg aaagggtttg ttcgtttcag acggcattgt taccaaggct tgattatttc
    13681 cggcgcaggt cgggatggtt ttccaagttg tccatcatta tcccgatgat gcgcggggcg
    13741 gttttgccca aatcgaaacg ttcgcaggaa gagaaccacc gccaaatcag cccgtccaag
    13801 gttgatttga tgaagatgac cgctgtttcc ttgtccaaat cgtcagccaa atcctgattt
    13861 tccaccgctt cggtcaaaac ggcggtaatt ttctcgcgcc agattgcctg atgcttgcgg
    13921 gcaatggcga taacggcggc gttttgttcc gtgtgttcgc attttaaaaa caggatgttg
    13981 tggaatttgt agtagatgtc gttgctttgc agccgctcga aaaagtgcag cagcgtgtgg
    14041 cggaataccg cccaagaccc tccttcggca tcttcggcat cttgcgcgat gcagttttcg
    14101 atgtcgtcgc agatacgttg gaacagcgcg tcgaacaagt cttccttatt tttgaaatgc
    14161 caatagagcg cgccgcgcgt tacgccggcg gcttgggcga tttcgttgag cgaggtgcgc
    14221 gcaatccctt tgcggtaaaa ggtttccaag gcggcaagca tcaggtgttc tttggttttc
    14281 aaggcttcgg ttttggtttt tctcataatg gcgttttcgt ttcgggtcgg tttgatgagg
    14341 gcggattata aaaaagactt tgtaaccatg caatcgtgta tgtataatga aacccatgaa
    14401 attgagacta catctcaact ttgaaaacag gcataacctg ctttgcaacc cgttcgaaca
    14461 ttcgggtatc aaagcaggcg gtttttatat cctgaaatat agtggattaa caaaaatcag
    14521 gacaaggcga cgaagccgca gacagtacag acagatagta cggaaccgat tcacttggtg
    14581 cttgagcacc ttagagaatc gttctctttg agctaaggcg aggcaacgcc gtactggttt
    14641 ttgttaatcc actataagaa tgcctgttga ttggcaaaac cctttacatc aaactagaca
    14701 gataggataa ataatggctt tttatgcttt taaggcgatg cgtgcggccg cgttggctgc
    14761 cgccgttgca ttggtactgt cgtcttgcgg taaaggcgga gacgcggcgc agggcgggca
    14821 gcctgctggt cgggaagccc ctgcgcccgt cgtcggtgtc gtaaccgtcc atccgcaaac
    14881 cgttgcgttg accgtcgagt tgccggggcg tttggaatcg ctgcgtaccg ccgatgtccg
    14941 cgcccaagtc ggcggcatca tccaaaaacg cctgttccaa gaaggcagtt atgtccgtgc
    15001 cggacagccg ctgtatcaga tcgacagttc cacttatgaa gcaggtctgg aaagtgcgcg
    15061 cgcgcaactg gcaacggctc aggcaacgct tgccaaagcg gatgcggatt tggcgcggta
    15121 caagcctttg gttgccgccg aagccgtcag ccggcaggaa tacgatgctg cggtaacggc
    15181 gaaacgttct gccgaggcag gtgtcaaagc agcacaggcg gcaatcaaat ctgccggcat
    15241 taatctgaac cgttcgcgca ttaccgcgcc gatttccggc tttatcggtc agtccaaagt
    15301 ttccgaaggt acgctgttga atgcgggcga tacgaccgtg ctggcaacca tccgccaaac
    15361 caatccgatg tatgtgaacg ttacccagtc tgcatccgaa gtgatgaaat tgcgccgtca
    15421 gatagccgaa ggcaaactgc tggcggcgga tggtgtgatt gcggtcggca tcaaatttga
    15481 cgacggtaca gtttaccctg aaaaaggccg cctgctgttt gccgatccga ccgtcaacga
    15541 atcgaccggt cagattaccc tgcgcgccgc cgtaccgaac gatcagaata tcctgatgcc
    15601 cggcctgtat gtgcgcgtgc tgatggacca agtggcggtg gataacgcat ttgttgtgcc
    15661 gcagcaggcg gtaacgcgcg gtgcgaaaga taccgtgatg attgtgaatg cccaaggcgg
    15721 tatggaaccc cgcgaggtaa cggttgcgca acagcagggt acgaattgga ttgttacgtc
    15781 gggtctgaag gacggggaca aggtggttgt ggaaggcatc agtatcgccg gtataacggg
    15841 tgcgaaaaag gtaacgccca aagaatgggc gtcgtctgaa aaccaagccg ccgcgcctca
    15901 atccggcgtt cagacggcat ctgaagccaa aactgcttct gaagcggaat aaggaaggca
    15961 tcgatggcta aattttttat cgaccgccct atttttgcgt gggttatttc gattttcatt
    16021 attgcggcgg gtattttcgg catcaaaagc ctgcctgttt cgcaatatcc gtctgtcgcc
    16081 gccccgacca ttactttgca cgccacttat ccgggtgcgt ccgcgcaggt aatggaagac
    16141 agcgtgcttt ccgtgatcga gcggaatatg aacggcgtgg aaggtttgga ttatatgtcc
    16201 acttccgccg attcgagcgg cagcggcagc gtgagcctga cctttacgcc cgataccgac
    16261 gagaatctgg cgcaggtgga agtgcagaac aagctttccg aagtattgag cacgctgccg
    16321 gcaaccgtcc agcaatacgg cgtaaccgta tccaaggcgc gttccaattt cctgatgatt
    16381 gtgatgcttt cgtcggatgt gcagtcaacc gaagagatga acgactacgc gcagcgtaat
    16441 atcgttcccg aactgcagcg tatcgaaggc gtggggcagg tacgcctgtt cggcgcgcaa
    16501 cgcgcgatgc ggatttgggt tgatcctaag aaactgcaaa actacaattt gtcgtttgcc
    16561 gatatcggca gtgcgctgtc cgcccagaat gtccagattt cagcgggttc tatcggttcg
    16621 cttcccgccg ttcgcggaca gacggttacg gctaccgtaa cggcgcaagg gcagttgggt
    16681 acggcagaag aattcggcaa cgtcatcctc cgcgccaata ccgacggttc taatgtttac
    16741 ctgaaggatg tggcaagggt cggactgggt atggaagact attcttcctc aacccgtctg
    16801 aacggtgtaa ataccaccgg tatggcggtg atgctgtcca acagcggcaa tgcgatggcg
    16861 acggcaaagg cggttaaaga acgcatggcg acgttggaaa aatactttcc tcagggtatg
    16921 agctggaaaa ccccttacga tacttccaaa ttcgtcgaaa tttcgattga aaaagtgatt
    16981 catactttaa tcgaagcgat ggtgctggtg tttgtcgtaa tgtatctctt cctgcaaaac
    17041 atccgttata cgctgattcc gaccatcgtc gtaccgattt cgctgttggg cggtttcgct
    17101 ttcatctctt atatgggcat gtcgattaac gtactgacca tgtttgcgat ggttttggtc
    17161 atcggcatcg tggtcgatga cgcgattgtg gtggttgaaa acgtcgagcg cattatggcg
    17221 ggtgaaggct tgccgcccaa agaagcgacc aaaaaagcga tgggtcagat ttcgggcgcg
    17281 gtcatcggta ttaccgccgt tctgatttcc gtgttcgtac cgttggcgat gttcagcggg
    17341 gcgacgggca atatttacaa acagtttgcc ctgacgatgg cgtcatcaat cgcattttcc
    17401 gccttccttg cgctgaccct tacccctgct ttgtgtgcca caatgttgaa gacaatcccg
    17461 aaagggcatc acgaagagaa aaaaggtttc ttcggctggt ttaacaagaa attcaacagt
    17521 tggacgcacg gttacgaagg ccgggttgcc aaagtgctgc gtaagacttt ccgcatgatg
    17581 gttgtctata tcggcttggc ggttgtgggc gtgttcctgt ttatgcgcct gccgacttcg
    17641 ttcctgccga ccgaagacca aggcttcgtc atggtcagcg tgcaactgcc tgcaggagcg
    17701 acccaagagc gcaccaatgc gactttggcg caagttaccc aactggcgaa aagcattcct
    17761 gaaatagaaa acatcattac cgtttccggc ttcagctttt cgggcagcgg tcagaatatg
    17821 gcgatgggtt ttgccatatt gaaagattgg aacgagcgta ccgcgcccgg cagcgatgcc
    17881 gttgcgattg ccggcaagct gacgggtatg atgatgggga cgcttaaaga cggttttggc
    17941 atcgccgtcg tcccgcctcc gattctggag ttgggcaacg gttcgggtct gagcatcaac
    18001 ctgcaagacc gcaacaatac cggccatacc gcattgctgg cgaagcgcaa cgagttgatt
    18061 cagaaaatgc gtgccagcgg tttgtttgac cccagcaccg tccgtgccgg cggtttggaa
    18121 gactcgccgc agttgaaaat cgacatcaac cgtgccgccg cggcggcgca aggcatttcg
    18181 tttgccgaca tccgcaccgc attggcaagt gcgctgagtt cgtcttatgt cagcgacttc
    18241 ccgaaccaag gccgtctgca acgcgtgatg gtgcaggccg acgaggatgc ccgtatgcag
    18301 cctgccgata ttttgaacct gaccgtgccg aacaaatccg gcgtcgccgt accgctttcc
    18361 accattgcta ctgtttcttg ggaaaacggt acggaacaga gcgtacgctt caacggttat
    18421 ccttcgatga agctgtccgc ttcgcctgca accggcgttt ccaccgggca ggctatggcg
    18481 gcggttcaaa aaatggttga cgaattgggc ggcggttaca gcttcgaatg gggcggacag
    18541 tcgcgcgaag aggcaaaagg cggctcgcaa accctgattt tgtacggttt ggcggttgca
    18601 gccgtatttt tggtacttgc cgcgctttat gaaagctggt cgattccgct ggcggtcatc
    18661 cttgtgattc cgttgggttt gatcggtgcg gctgcgggcg taaccgggcg caacctgttt
    18721 gaaggactgt tgggcagcgt tccctcgttc gccaacgaca tctactttca agtcggtttc
    18781 gttaccgtga tgggtttgag tgcgaaaaac gcgattttga ttatcgaatt tgccaaagac
    18841 cttcaagcgc aagggaaaag cgcggtcgaa gctgctttgg aagccgcccg cctgcgtttc
    18901 cgtccgatta tcatgacctc gttcgccttt attttgggcg tggttcccct gtatattgcc
    18961 ggcggtgcaa gttctgccag ccagcgcgcc atcggcacga ccgtattctg ggggatgctc
    19021 atcggcacgc tcttgtccgt gttccttgtt ccgcttttct atgtggtggt gcgcaaattc
    19081 ttcaaagaaa ccgcgcacga acacgaaatg gcagtaaaac acgccgccga agcgggcatc
    19141 accggttcgg acgacagcca acattaagca accatgacgt ctgaacgcct acgggttttc
    19201 agacggcatc aggacttttt tatggatact acattgaaaa ccaccttgac ttctgttgca
    19261 gcagccttcg cattatccgc ctgcaccatg attccccaat acgagcagcc caaagtcgaa
    19321 gttgccgaaa cgttcaaaaa cgataccgcc gacagcggca tccgtgcggt cgatttaggt
    19381 tggcatgact attttgccga cccgcgcctg caaaagctga tcgacatcgc actcgagcgc
    19441 aataccagtt tgcgtaccgc cgtattgaac agcgaaatct accgcaaaca atacatgatt
    19501 gagcgcaaca acctcctgcc cacgcttgcc gccaatgcga acgactcgcg ccaaggcagc
    19561 ttgagcggcg gcaatgtaag cagcagctac aaagtcggac tgggtgcggc atcttacgaa
    19621 ctcgatttgt tcgggcgtgt acgcagcagc agcgaggcgg cactgcaagg ctatttcgcc
    19681 agcaccgcca accgcgatgc ggcacatttg agcctgattg ccaccgttgc caaagcctat
    19741 ttcaacgaac gttacgccga agaagcgatg tctttggcgc aacgtgtttt gaaaacgcgc
    19801 gaggaaacct acaagctgtc cgaattacgt tacaaggcag gcgtgatttc cgccgtcgcc
    19861 ctacgtcagc aggaagccct aatcgaatct gccaaagccg attatgccca tgccgcgcgc
    19921 agccgcgagc aggcgcgcaa tgccttggca accttgatta accaaccgat acccgaagac
    19981 ctgcctgccg gtttgccgct ggacaagcag ttttttgttg aaaaactgcc ggccggtttg
    20041 agttccgaag tattgctcga ccgtcccgat atccgtgctg ccgaacacgc gctcaaacag
    20101 gcaaacgcca atatcggtgc ggcacgcgcc gcctttttcc catccatccg cctgaccgga
    20161 accgtcggta cgggttctgc cgaattgggt gggttgttca aaagcggcac gggcgtttgg
    20221 tcgtttgcgc cgtctattac cctgccgatt tttacctggg gcacgaacaa agccaacctt
    20281 gatgcagcca agctgcgcca acaggcacaa atcgttgcct atgaagccgc cgtccaatcc
    20341 gcctttcaag acgtggcaaa cgcattggcg gcgcgcgagc agctggataa agcctatgac
    20401 gctttaagca aacaaagccg cgcctctaaa gaagcgttgc gtttggtcgg tctgcgttac
    20461 aaacacggcg tatccggcgc gcttgatttg ctcgatgcgg aacgcagcag ctattcggcg
    20521 gaaggtgcgg ctttgtcggc acaactgacc cgcgccgaaa accttgccga tttgtacaag
    20581 gcactcggcg gcggattgaa acgggatacc caaaccgaca aataaccggt cgggcaataa
    20641 aatgccgtct gaaacgataa ggtttcagac ggcatttctt tctttatagt ggattaacaa
    20701 aaaccagtac ggcgttggct cgccttagct taaagagaac gattctctaa ggtgctgaag
    20761 caccaagttg tactatttgt actgtctgcg gcttcgtcgc cttgtcctga tttttgttaa
    20821 tccactatat gtttgacggt tgcggtcagg ctgcgcggcg tgccgtaaac gtgaatgtcg
    20881 ggcatagggc ggtagcgttt gttgaacacg ttttcaaagt ccaaaccgat gcgggtggat
    20941 ttgccgattt tgtaatgcgc ggtcaaatac agtgtggcgt aggggcgttg ggtcaatgcg
    21001 gctgcggcgg cagggaagaa accgccatac ccgccggcat cccgaagccg aatacggcaa
    21061 cggcaagcgc aatcagcagc gtataaagcc ccgcctgata gcctttcagc ttcaggacgg
    21121 tcagcgcggc aaagaaaaag acgatgggta agagtgcggc ggcggcagtc agatacaggc
    21181 tgccgccgat tgccgtgtag ttttgaaccc aagtttccat aattgaacat ctccgaaaat
    21241 atttttctaa tcgtcggcaa tagtggtcaa accaattaaa gcaacgttgc attactttgc
    21301 gaaactttaa tattcaggtc aatagagtgg attaaattta aaccagtacg gcgttgcctc
    21361 gccttaccgt actatctgta ctgtctgcgg cttcgtcgcc ttgtcctgat ttttgttaat
    21421 ccactatata tttttgggcg gttcggcaga tttgaatcgg agctttcgtt taaatcctgt
    21481 caaaacaaat atttgcataa acaaaaattg tagtttggtg tagttttttc ctgtgtttcg
    21541 ggggcggtgc gaggtaaatg ccgttgacgg cgggaacggc gtgtcattag aatccgccct
    21601 gattggtcag tccaatttga tgtttgatgt atagtggatg aacaaaaacc agtacggtgt
    21661 tgcctcgcct tagctcaaag agaacgattc tctaaggtgc tgaagcacca agtgaatcgg
    21721 ttccgtacta tttgtactgt ctgcggcttc gtcaccttgt cctgattttt gttaatccac
    21781 tatatttcgg aagggttctg cagggaatct ttataaagga ggagtaatga aactggtaag
    21841 gcctcagaaa atcagcgatc aggtattgtc ggtattggag gagcgcattg cggaaggggt
    21901 ttacgcggaa gggggcaaga ttccgcccga acgcgttttg gcggaagagt tcggcgtgtc
    21961 ccgcccgtcg gtcaggtcgg cattgaatgt tttggttgcc cgtcaggttt tggaagcgag
    22021 gcagggagac ggttattatg tttcggtcaa gccacagcag gattttttgc aaagttggca
    22081 ggagcttttg ggcaagcatt ccaattggga acaggatgtt tttgatttca gctgccacat
    22141 cgagggctgt atggcggcat tggcggcaga acgccggacg gatgccgatt tgaagcggat
    22201 tgggttttgg cttgaaaagt ttgaggaggc gtgcgaaagc ggcaatctgg aacatcagag
    22261 cgaagccgat gtcagcttcc atcagacgat tgcggatgcg gcgcacaatt tgttgttcag
    22321 ccatttgtcg ggcggtttgt tgaaaatgct gtaccggcag acgcgcagca gccttattta
    22381 tctgaatcag gaagaagatc cgcgtccgaa actgatggcg cagcaccgcg tgctgtatga
    22441 ggcgatatcg aaccgtcggc cgggcgaggc ttcggaggcg gcaaaggcac atttgaatta
    22501 tgtggcaagc agcatcatga aagacaggga atatcagagc cgtaaccgcc acgcggatac
    22561 tttggcgcaa aacgatttga agcgcgtgca ggattgggag gtatgaatac cgtttagacg
    22621 gtctggcata ttcggatgta tcggtatagt gaactaaatt taaaccagta cggcgttgcc
    22681 tcgccttagc tcaaagagaa cgattctcta aggtgctgaa gcaccaagtg aatcggttcc
    22741 gtactatttg tactgtctgc ggctcgccgc cttgtcctga tttttgttaa ttcactgctg
    22801 accaatcatt atccgccaga taaagtattc tgcttcatcc ttgtctattt ccagcaggag
    22861 aaagccaacc acttgcttat cccaatagat tgccctcgga aacacatctt cattttcccg
    22921 gtagagccat gcgtcagcta aagagcgtac atttggagcc acaaaacgtg ctcgttcatc
    22981 agcttcagat attttcaaat ccagcactgc ctgaaaactg ctctcatcta ctaatttcag
    23041 ctcaatcatt ttttctcctt ttgaataaat agggttttga ggtgattaaa gactaatcta
    23101 actcatataa aaggtagtta tcaaaattta tgattccttt gaggtaatct cggtctgctt
    23161 tagacaactc aaattctgga aaagtcgcaa ttaaactgga caaataaaaa taattcgggt
    23221 gcctacgata agaaaaacct gcttgaccga atttcccttg acaaaaatca taggcaagtt
    23281 tcaattcttg acttgtgaca ccgtctaaaa ttttatctaa ctctgaaagc tgacttttat
    23341 cagtattttc tatcatagct ttcactgtat ttactaaaac aaaaagaaaa tcattagtat
    23401 tatccagtag gattggtctg ttagataact tattctttaa ctccatatag tattggtcca
    23461 taatcatttc ttcctctcca ctcccaaact atccaacaat tctggataca aatagtatca
    23521 cccgattcga acgggcggat aatgaaatgc cgtctgaaca gcatttgcgg ttcggacggc
    23581 attttgtttg cggagcggcg gcgtttgctt agaagccttg cgccagcatc gcatcggcaa
    23641 ctttgacgaa accggcaatg ttcgcaccat tgacgtagtt tactgtgtcg ccgactttgc
    23701 cgtatttcag acaggattcg tggatgcttt gcatgatgcc gaacaggcgt tggtcgactt
    23761 cttcacgagt ccaagacagg cggatggcgt tttggctcat ttccaaacct gaagttgcta
    23821 cgccgccggc attggaggct tttcccgggg cgtagaggat gccggctttg ataaattgct
    23881 cgaccgcgcc caaagtcgac ggcatattcg caccttcggc aacgacgtag cagccgtttg
    23941 ccaacagggt tttggcggct tcttcgtcca attcgttctg ggtcgcgcag ggcagggcga
    24001 tttcggcggc gacgccccac ggtttttggt tttcaaagta ttgcagacct tgctctttgg
    24061 cgtaggtggc aacgcgttcg cggcggactt ctttcaattc gatcaaggcg gcgagttgcg
    24121 cttcggtcat accgctgtcg gggaagagga cgaagccgtt ggagtcggaa acggtcagca
    24181 ctttcgcgcc cagttggatg gctttttcgg cggcgtattg cgccacgttg ccggaaccgg
    24241 aaatcaggac gcgtttgcct tcaaaactat cgttgcgggt ttgcagcatc gcttgggcga
    24301 aatagacgca gccgtagccg gtcgcttcgg gacggatgag gctgccgccc cattccaaac
    24361 ctttgccggt caggacggaa gaaaactcgt tgcggatttt tttgtattgt ccgaacagat
    24421 agccgatttc gcgtccgcct acgccgatgt cgccggccgg aacgtcggtg tccgcgccga
    24481 tgtggcggta gagttcggtc ataaaggctt ggcagaagcg cattacttcg gcatcggatt
    24541 tgcctttggg gtcgaagtcg gaaccgcctt tgccgccgcc cataggcagg gtggtcaagg
    24601 cgtttttgaa cacttgttca aaagcgagga atttcaatac gcccaaatcg acggtcggat
    24661 ggaagcgcag gccgcctttg taaggaccga tggcggaact catttgcacg cggtagcccc
    24721 ggttgacttg gacttgccct ttatcgtcct gccaggttac gcggaacatg acgacgcgtt
    24781 cgggttcgac gatgcgttcc agcaggcttt gctgggtgta tttcggattt tttgccaaaa
    24841 acggatcgag actcatgaag acttcttcaa ccgcctgatg gaacggctcc tgattgggat
    24901 tgcgttgttt gaggttggca aacagggtgt tcaggtcagt cattcggata ctccttttgg
    24961 ttgatagtgt actaatggga aaacaaattt gtaggtggga atataaacct atttttttct
    25021 gatgccaagc ccgatttggc aaaaattgtt gacattattt tttccatgtt ttcgatgttt
    25081 gatgtttgtt gccgataatt aatcaataat cataaattaa tttcgtaaat aaaaatatta
    25141 ttgaaatttt attctaagta attaaactag attttttgat tccaatcaag gtaattttgt
    25201 tttcccaccg ggttttactg tggaaaagga ctgaaattgc caacaatcct gcctgtctgt
    25261 atccgtgttt tgggcattat ccggaaatgt tacaatatgc gccgtttaat ttgatgaaag
    25321 actgctatga aagcctattt ggacttgatg cgccacgtcc tcgacaacgg tacggacaaa
    25381 tcagaccgca ccggtacggg cacgcgctcc gtattcggtt atcagatgcg ttttgacttg
    25441 ggcaaaggtt ttccgctgct gacgaccaaa aagctgcatc tgcgttcgat tatctacgag
    25501 ctgctttggt ttctcaaagg cgataccaat atcaaatacc taaaggacaa caatgtttcc
    25561 atttgggacg agtgggcgga cgaaaacggc gacttaggcc cggtttacgg ctaccagtgg
    25621 cgtaactggc ccgcgcccga cggcaggcat atcgaccaaa tcgccaatgt ggtggaacaa
    25681 attaagaaaa accccgactc gcgccgcctg attgtatcgg cgtggaatcc ggctttggtc
    25741 gacgaaatgg ccttgccgcc ctgccacgcg ctgtttcagt tttacgttgc cgacggcaaa
    25801 ctgtcctgcc agctttacca gcgtagtgca gatattttcc ttggtgtgcc gtttaatatt
    25861 gccagctacg cattgttgac catgatgatg gcgcaagtgt gcggattgga ggcgggcgag
    25921 tttgtccata cgtttggcga cgcgcatttg taccgcaacc atttcgagca ggccgcattg
    25981 cagttggaac gcgaaccgcg cgccttgcca gtgatgaaaa tcaatcctga agtcaaagat
    26041 ttgttttcct tcaagtttga agatttcgag ttggaaggtt acgaccccca tccgcacatc
    26101 aaggcggcag tgtcggttta ggaggcggta tgggcaggca tttcgggcgc aggcgttttt
    26161 tgacagttgc cgccgttgcg gcggcgggcg cggcggtttc tttcctgccg aatccttttg
    26221 ccgccgatga tgaaaaacgc aataaagatg aaaaacgcaa tgaaaatgtg ttcttctgga
    26281 aaggtgtcgc gctgggttcc ggtgcggagc tgcgcctgtt cggtgtggac gacagacagg
    26341 cggcggattt ggtcaacaag gttttggcgg aagtggcgcg tttggaaaaa attgttcagc
    26401 ctttaccgtg aagacagcct gatcagccgc ctgaacaggg acggttatct gacttcgccg
    26461 tcggcggatt ttttggaact gttgagcctg tgccgcgata ttcacgcgct gacggacggc
    26521 gcgttcgatc cgacagtgca ggcgttgtgg aaactgtatg ccgattattt tgccgcccgt
    26581 cccgatgcgg aaacgccgcc tcctcaaaac agcgtgaagg aagccctgaa acgggtcggc
    26641 ttcggcaaag tctcgtttga cgaccgtgaa atccgttttg ccgaaaaggg tatgggtttg
    26701 tccttgaacg gcatcgcgca aggctatagt ggattaacaa aaaccagtac ggcgttgcct
    26761 cgccttagct caaagagaac gattctctaa ggtgctcaag caccaagtga atcggttccg
    26821 tactatttgt actgtctgcg gcttcgtcgc cttgtcctga tttttgttaa tccactatac
    26881 tttgaacgaa ataggctgaa cctgaagcaa aaatgccgtc tgaaaggctt tcagacggca
    26941 tttttgctgt ttggatggct tttaaaggat gtccaaagaa ttgatgaaaa caataataat
    27001 ggcaatcggg gcgaggtagc gcaaggtatt cagccacagc agcaacactg cccgtggtac
    27061 ggtgctgccc gcgccggcat cttttaacac agactgcctg tcctgaatcc aagcggtaaa
    27121 tacggcaacg ctcaatgcgc cgacaggcat gatgactgca gaaataaggt agtcccacaa
    27181 atcaaaaatg gttttgccga aaaccttaaa ctcaccccat acgccgaaag acagcgcgga
    27241 cgggatgccg acaataaaaa tagccgtgcc gataagccaa gtatgttttt tgcgtttgcg
    27301 ctcgtcttgg cggatggttg cggcgatgac cgtttccaac atcgaaaatg ccgaagtcag
    27361 cgtggcgaaa acgaccagca gcataaatac cgcaaacaaa accgtaccga acggcatttt
    27421 cataaacacc gccggcaata cgataaaaat caatcccggc ccctggctcg gttcaaaacc
    27481 gaaggcgaac accgccggaa aaatcaccaa acctgccaac agcgaaacca agaggttcat
    27541 ccacataatc gtatgccccg agcggaacat atcctgatct tttcccaaat acgaagcata
    27601 ggtaatcata gcggaaacgc cgatgctcaa ggcaaaaaac gcctgaccta aagccgtaat
    27661 catcgtatcg gctttaaagt acgaccaatt cggtttgagc aggaaagaca cgccctccat
    27721 tgcacccggc agcgtcagcg aacggattgc cagcgcaata aagaggataa acagccccgg
    27781 catcagataa cggtttgcct tttcaatgcc gtctgaaatg ccgcctttga ccacccaaac
    27841 cgtaatcagc ataaacagtg cctgatagga cagcgaacct gccggattgg aaatcgtcgc
    27901 gccgaacaag gcttcaaagt ccgcgccggt atgaaccgcc cccgtgaaac tgtggacgac
    27961 ataatttaat acccatccgc cgaccacgct gtaaaacgac agcaaaataa agcaggcgga
    28021 aacgcccatg cgcccgaccc aaagccattg cgtactcgga cgcagagccc tgaaggaatc
    28081 gacggcattt ttaccgcctg tgcgcccgat ataaaactcg gcaagctgga cgggcagggc
    28141 gaccaagacg gtaaatatca aaaacagcag gaaaaacacc gcgccgccgt tggtgcctgc
    28201 cgtataagga aatttccaaa tcgcgcccaa accgatggcc gaacctgccg cagcaagcac
    28261 gaaaccgatt ttggacgacc aagaagtatg gttactcata aaatttatta agaaatgtga
    28321 agatagtata gtggattaac aaaaatcagg acaaggcgac gaagccgcag acagtacaga
    28381 tagtacggaa ccgattcact tggtgcttga gcaccttaga gaatcgttct ctttgagcta
    28441 aggcgaggca acgctgtact ggtttttgtt agtctactat acattgtaac aaagcacttg
    28501 atgcggcagc acaagccggg gaagacgctg caaaactttg ccaataggct gcgtaatatc
    28561 gggggatatt gggattttct tatttttaag gatggattcg gggtgtttct ttccaatgaa
    28621 cgaatataat ttggcggttt gttgcatcaa aggctttcag acggcatatg ccgtctgaaa
    28681 gcagtttata ttgcatccaa taatttgtcg gcggtatggt tgatggtaaa acggttggcg
    28741 acgcattgat gtcctgccgt tgccagtgcg tttttcgttt cagggttcaa gacgaggcgt
    28801 tcgatttcgt ccgccaaaga ttcaggtgtc agcctgtcca gcagaatccc cgattgatga
    28861 tgttcgataa tttccttttg cgcccccaaa gtattggaaa tcaccgccgt tcggcagtac
    28921 atcgcctcgc ataatgacaa accgaatgcc tccgggacga ggctgggcaa aaccacgaca
    28981 tcgctttggc ggtaaaacga agcaagtttt tcggtaaacc cttcaaaaga aacaaatggt
    29041 tctgctcctg aagcagatac gtcccgcttc aggcggcaca tataatccgg atgtccgtcc
    29101 cctgccaatt tgagcctgat ttgaggatat ttccgatgca gtatcacaca ggcttcaatc
    29161 aggttttcca atcctttttc tggactgatc ctgccggcgt aggcgacggt aaaaaaacgg
    29221 ctgtcgggtt tttcttgaga gggagggaaa cggccggtat cgataccgtt atgaacaatc
    29281 cggtattttg ctttaaaggg attgtcggcg gtttgcacat cgtaaaccag acgggaaacg
    29341 caaataaagc ggtctgtgtt tttctgtatc aggcggtggt aaaaatcggt tttgttggcg
    29401 acgacattat gtttgacaaa tatcaggcgc accccggtca gttttttcaa aagtatggat
    29461 aaggcggcaa ttttgccggt gtgtatcatc aggtgggaaa tgcggttttt ccggataaag
    29521 cgggtaagcg cgcagagcga aaacagcccg ttgagcgtgt gaaggcgcgt tgtgaaaacg
    29581 gaagaaactt cggaaaaacg tctgtgcatc aactcattat ttttattgac ggcggtaaac
    29641 atcgtgcaac cccgaagccc caatgctttt gaaacatcat agacatactg ttcgcccccg
    29701 ccccaaatct tggccgatac gatatttaat atcctgaatt ctttttccat ttaaaatttt
    29761 ccgccagatt tgtacagata atatagtttg acatatttaa tcatcgtgta atagctgtgg
    29821 ttgacggaca taatccaacc catttttcca tcgagaaacc ctttgttcag gatataaatt
    29881 ttgaaaaaac cccaaatcgg gcggaggata atgtccctaa cgaaacgcac gggctttccc
    29941 tgctctcggt atttctcggc tgagatggaa gtgtatttgt tgaatttgtt gaaatattgt
    30001 tcccagttgt cgtatgtgta atggtacata aaatgcttca gacggcgttt ggggtagggg
    30061 gtttgtacgg tttcgtgtac tttgccttgc accgaactgt cttttttcgg catcagacgg
    30121 catacgctgt cgggacgcat cgcgccgtgt gtggcgggat ggttggggaa aaggttgcgg
    30181 cgctcgacaa aataggcggc ataatcgccg gtttggacaa tttttgagat ttcatcagat
    30241 agttccggcg tgcagcgttc gtctgcatca atcaggaaaa cccattctcc gcctgcctgt
    30301 tctatggcaa atgttttttg cgctccgaaa tccccgttca aatgccgttg gaagactttt
    30361 gcacccaaac cctcggcaat ttcggcagta ttgtcggtgc tgtggtcgtc gataacgata
    30421 acttctttat cgaaacggca actttcaata cattcccgaa tgtggtttgc ttcgtttttg
    30481 gcaacaatca atacgctgac ttttttcatt atcaaggttt ctcaaagcat tttggtttca
    30541 cagggcggca aaaaagccca aacatacgtc cgggcttggg aattggtggg tccggtgggg
    30601 ttcgaaccca cgaccaaggg attatgagtc ccctgctcta acccctgagc tacagacccg
    30661 tcaagagtag gcgcgtattg tatagcatag cggtgggatt gacaaactta tttcatccga
    30721 tgattaagac gcagttgctt cctccgaagg caaacgacga gctggcggca atgtgttttt
    30781 cggtttccca gcggctgccg ctgccggtca ggttgatggc gggcaggtcg gggtcgttct
    30841 gcccgtccca aagccggggc ggaagtttcc cttcgggatt gctttgccgg tcggcaatgc
    30901 cccacgcgaa cgcggcttcg attgcgcccg ccgcgcccag cgtgtgtccg gtttgcggct
    30961 tggtggacgt gcagggcgta ttgttgccga aaaccgctgc aacggcacgg ctttccatac
    31021 tgtcgttgtg gtgcgtcccg gtgccgtgca gattaatcca gccgatgtct tcgggcgcaa
    31081 gacctgcgtg ttgcaatgcc gtctgaaagg caaggattgc gccttgcgcg tcggggcggg
    31141 gcgtggaaat atggtaggca tcgctgttgg ctccgtagcc gacgagttcg gcgtaaatta
    31201 tcgcaccgcg ccgtttggcg tgttccaatt cttccagcac gaaaatcccc gcgccttcgc
    31261 cgatgaccag cccgtcgcgg ttcgcgtcgt atgggcgcgg ggttttttcc ggttcgccgt
    31321 tgcggcggct ggcggcataa agcgagtcga aaacatacac ttcggacgag aaaaattctt
    31381 cgcctccgcc cgccagcatc atatcggtca gaccgtattt gatggcttcg taggcataac
    31441 ctatgccttg gctgccggac gaacacgcgc tcgatgtcgg gatgatgcgt cctttcagcc
    31501 cgaaaaagat gccgatattg gcggcggtgg tgtgcggcat catacgcaca taggtgttgg
    31561 cactgaagtt gcgcgacgtg ccggtcagca acaattcgcc cacatcgccg atgtctttgg
    31621 tgctgccgct ggaagagccg caggcaacgc ccatccgtcc gtcggtaatg ctttcgtccc
    31681 cgagcaaacc ggcatccgtc aaagcctgct ccgccgcatc gacgcacaaa tacgacacac
    31741 gccccatact tctgagctgc ttgcgcgtcc aatgtttcgg cggcgcgtaa tcctcaatcg
    31801 gcgcacccag ttgcgcttcc aattcgggga aacgttcgtg ccaatccact atattttcgc
    31861 aagacgcgtt ttgcctgatt ccaaaagttc tcaatgccgt taatgtggtt ttgacggtct
    31921 gcaaattcct tggaatggtt gatgcggtaa tggataaaac tgctcacgtc caacttgtcg
    31981 cagctgctca gactatcggt ataaacaata ctgtccggca tgattttctt tttgatgaca
    32041 gggagtaacg tttcagactt ggcattgttt acgacaacgg tatagacccg tccgttgcgt
    32101 ttcagaatgc cgaaaacaac cacttttcct gccgcaccgc gaccacgtct gcctttacgc
    32161 cgtccgccga aatcgctttc gtccggctcg acaggatcct caaaaacctc atcggcagcc
    32221 aagaccaaat gatggttgat aaccgtgcgg attttacggt agaacagtgc tgccgaattg
    32281 ggatggatac ccaaaatatc ggcggcagaa cgggcggtaa cttccagtac aaaaaaatgg
    32341 agcagttctt tctgtacttt tttctttaat ttgcagtgtg ttatcttcat atttcgaggg
    32401 taacatatct gctaatctag taaaatttaa tccactatag tttatgcctc gcacgacggg
    32461 gaaatggcgc gcagtttcga tttgtggttg gaactgttga aatcgcaaat cgtgtcgccg
    32521 acttcgttcg gtttgtcggt gcacaatgca acggcggggt aatggtcgat attgaggcgg
    32581 gatatgagcg agcagacggc attggccgtg tgtgccgacg gtgtggaaac ggcattggcg
    32641 gaagcggcat cactgttgga agagggatgc gggtcggttt tggttttggc ggcggacgat
    32701 ccgctgccgg aaggatatgc cgtatcggca acgcgcgcgc cgtttgctta tgctttggcg
    32761 atggttctga ccaaagggac gcgttacagc ctgactttat ctgcttcgga cgatatgccg
    32821 tctgaagccg gtatgctgcc cgaggcatat tggagcggtt tggaatgggt gcgctttctg
    32881 ctgaacggca gtcgggaatg ccgccgggta tatcgcaatc gtgaatggct gtggcagccc
    32941 gcaagctgca ggctgaagat ttccgcaatg tccgcaccgt caacgacgtg gtacaggcgg
    33001 tattgaagat tcaggcgggc taatcgggta tttctaatta tttttcagac ggcatgtttt
    33061 tatcggatgc cgtctgaaaa catttgtgcg gattcaaaat gaaacccggt tttttcggac
    33121 atatttttct gaccgtatta agcattgcct atcccgcttt gtggtatagt ggattaacaa
    33181 aaatcaggac aaggcgacga agccgcagac agtacggcaa ggcgaggcaa cgctgtactg
    33241 gtttttgtta atccactata ttacggcagg gaggcgggct ggtttgtctg gctggcggcg
    33301 gcgatgtgcg ggttgtggct gctgcgcgcc ctgactgcca aactgcccca acagcgttat
    33361 gcggctttgt ttattacact gttttttgcc gcagtattgg tgttcgggcg gcatgattcg
    33421 atgtattggt atcccgtcct cgtcaatctg atgatgttgg cggtgttcgg cggcagcctg
    33481 tttgccggac agacggtcat agaaaggctc gcgcggctgc aacagcccga cctgcctgaa
    33541 aaagctgtgc gctatacccg ccgggtaacg caggtttggt gcgtattctt tattgccaac
    33601 gggacgcttg ccgctttgtt ggcccggttg gggcgatatg attggtgggc ggtttataca
    33661 ggcgtgattg cctatgtatt gatggggatg ctgtttgccg gcgaatggct ttaccgcaaa
    33721 ctcgttttga aagtctgaaa ccttatgtac acttgcactt cctgcggcga aaaacatgaa
    33781 gatatgcccg caatcggctt taccgccccc gatccctata atcaactcag tgaagaagaa
    33841 cgcattgctt atcaagcaga atgcgattct gatttctgca tcatccgcta tcccgaccaa
    33901 accgaccgct ttatccgcgc ggtgctgccg attccgatta tcgggcatga ggaaacgctg
    33961 gaatatggcg tgtgggtgtc cgtcagcgaa aagagtttta acgactatca aagccacttt
    34021 cacgacaatc cggaaaacgc cgtttatttc ggcatgatct gcaaccggct gccctcttat
    34081 gaatccgaca ccttcggttt gcattgcaat gtcgttaccc aacccgatgg tcaacgccct
    34141 ttgctgcaac ttcatcaaag cggcggacat ccgctggtac gcgactttta tcacggcata
    34201 gaatatgccg aagcacaggc aaggataggg gcggtatccg aatcggattg ttcaggataa
    34261 aaggacaaaa aggataaata tgaaatacaa agacctgcgc gacttcatcg tcatgctcga
    34321 gcagcaaggc aaactcaagc gcgtcgccca ccccgtttcc ccgcatttgg aaatgaccga
    34381 aatcgccgac cgcgtgctgc gtgccgaagg gtcggcgttg ttgtttgaaa acccgattaa
    34441 gcccgacggt acgcgctacg attatcccgt gttggcaaac ctgttcggca cgcccgaacg
    34501 tgtggcgatg ggcatgggcg cggacagcgt gtccaagctg cgtgaaatcg ggcagacgct
    34561 ggcgtatttg aaagaacccg aaccgcccaa aggcatcaaa gatgcgtttt ccaaactgcc
    34621 gctactgaaa gacatttgga gcatggcgcc gaacgtggtg aaaaacgcgc cgtgtcagga
    34681 aatcgtgtgg gaaggcgaaa acgttgattt gtataaactt ccgattcagc attgctggcc
    34741 ggaagacgtt gcgccgctgg taacatgggg cttgaccgta acgcgcgggc cgcacaaaaa
    34801 acgccaaaat ctcggcattt accgccaaca actcatcggc aaaaacaagc tgattatgcg
    34861 ctggctgtcg catcgcggcg gcgcgttgga ttatcaggaa ttccgcaaac tcaatcctga
    34921 tacgtcgtat cccgtctccg ttgtgctcgg ctgcgacccc gccaccattt tgggcgcggt
    34981 aacgcctgtt cccgatacct tgagcgaata ccagtttgcc ggactgctgc gcggttcgcg
    35041 gacggaactg gtgaaatgta tcggcaacga tttgcaagtg cccgcacgtg ccgaaatcgt
    35101 actggaaggc gtcattcatc cgaacgaaac cgcgttggaa ggcccatacg gcgaccacac
    35161 gggctattac aacgagcagg attatttccc tgtgtttacg gtcgaacgca ttaccatgcg
    35221 cgaaaacccg atttaccatt cgacctacac gggcaaaccg cctgatgagc ctgccgtttt
    35281 gggcgtggcg ttgaacgaag tgttcgtacc gcttttgcaa aagcagttcc ccgaaatcac
    35341 cgatttctac ctgccgcccg aaggctgctc ctaccgcatg gcggtggtga gcatgaaaaa
    35401 acagtacgcc ggacacgcca agcgcgtgat gatgggctgc tggtcgttcc tgcgccagtt
    35461 tatgtatacc aaattcatca tcgtggtgga tgacgatgtg aacgtgcgcg actggaaaga
    35521 agtcatctgg gcggtaacca cgcgcatgga ccccgtgcgc gacaccgttt tggtggacaa
    35581 cacgcccatc gactacctcg acttcgccag ccccgtcagc ggactcggcg gcaaaatggg
    35641 tttggatgcg accaacaaat ggccgggaga aaccgaccgc gaatgggggc gcgtcatcaa
    35701 aaaagaccct gcggttacgg cgaagattga tgggatttgg ggggaattgg gcttgtaggt
    35761 tttacggcaa tgccgtctga agcgcgaggg cgtttcagac ggcatttttg tacgcaggat
    35821 gtttacggtt ctttaggttt gagccactgc cattgttcca gcagggtgtc ttcgaggatt
    35881 ttctgtttct ctttgcgcga attgatgccg ccggtcagcc tgccgtaatc gacggtaatg
    35941 gacggcttgt ccaccgtacc ggtgattttc aggggaatcg gtttgttttt cggatggacg
    36001 gcgttgcgga taaggacatc ttcagacaat tcctgcgtat ccagattggt atagccgttg
    36061 ctggtaacat agaggctgtc ggagaagagt tcggtatcga tgtggcggct gatgccgtct
    36121 gaaatttcgc tgttgagcgt gaatcggtgg aagggtgtgc tgggtgcggc attgtcggca
    36181 gttttgcccg aaatgccgtt tttcaggata ttgtccatgt cgataccgtg ccatgcaccg
    36241 ttggaaatat ttagcgacag gctgccctga agcgagcgga taagctcttt tcgggtttcg
    36301 ccgcccgcgg tcaggtcgat gaccgcgtcg ccgttgccgc tgaagctgtg gaagccgaac
    36361 aggtcttgca gcagcggttg gatttggatg ttgcttgcat tctgttgcag gcggtaagtg
    36421 gcgggacggg tgttggcgat gctgatgccg ccttcggtat ggccgccgta aagccctgac
    36481 ttgaaacggc tgagcgcgat atggtctttg tcggcgtgga ggtaggtttc catatcgtcc
    36541 agttgcaggc cgggaagttg gacttttccg attttcaggt gcgcctcgat gtcgccggac
    36601 agcttggcga gggtgtcggg aaatattttg ccgttttgtt gccgcacgtc gtcaagatag
    36661 ggggtcaggt tcaatttttg cagtgcgacg gcggcttcca gatgcggtgc gtcttcatgt
    36721 gtgtatctga atttcgcggc aacggtttgg cggtcgaatg tgccgtttaa ttcggcattc
    36781 caattttgca gattcggtac ggacagcgaa ccgtcgagcc ggctgatgaa acggggttgc
    36841 ggcaggcggt tgacggtatc ctgaagggtc gatacataca ggcgcggcgc gtccagccct
    36901 ttgttttccg tccatacgag cggcgaattg agggagaagt tggtctggtg gcgcggtgtt
    36961 ttgaagctgc cggagatttc ggcgttgccg atgttggcga tgccggagtg caggttggct
    37021 ttgtcgagtt tgaacgaacc gtcccatcgg gcatattcgc cgccgatggt aaatgcgccg
    37081 ttgacggttt caattttaat gctgttgttc ctgagtgcca gcgtagggat ttgggcggtc
    37141 aggtggaggt tgcggaagga agtgtctgca cgcaggccga ggccggcggc atccgctccg
    37201 ccggcgttga aacggacaga agggctgccg gtggtggaaa tggtgatgcc gtgtccgtcc
    37261 agcgaagtgg aagcttcaaa atggaacggt gagattttgg gcgtgccgat gccgtctgaa
    37321 aggaacagcc ccctgctttt ccacgggacg gacagctttc cccaaaccag tatgcccgaa
    37381 ctttcaaacg gctgccccga cgaatcgggg gattgcaggt tgaggttgat ttccttcagg
    37441 ataagctgtt cctgcaggaa attgaggcgg acggtgctgt tttcgacgat aatgcggttg
    37501 actgaggctt ggcgtttttg gctgtcgatc aggtcttgga tgttccaaac acctttcccg
    37561 tcgcgcgtca gggcaagttc cgcactcgaa accacccatt tttcaatctg tatctgatcc
    37621 gaccacaggt ttttccagct caatccgatt ttggtttctt ggacggaaac ggcagtccgg
    37681 tcgccgccgg gttcggtaat ggtcaggttt ttcaggatga cggtcggccg gggcaggagc
    37741 ctgcgctgaa tgtccgcatc aaacgagatt ttccggtgcg tatgagcaat gctttgttgg
    37801 aggcggcttc tgatgttttc aggtgtgagg atgcgatata cggaagcgtg cagcccgatt
    37861 gccgccaaaa gcagtatcgt cagcacggcc accgcatatt tcagacggta tttgtggaaa
    37921 accgataata aatccatagc ccgaacaatc tgtaaaacac gccacagtat aacacggctt
    37981 gcaaaaatcc tattttgggc aggccgtttc ttgtgtcagg aggaaatatg attattgtca
    38041 tgagcaggcg tgccgccgaa gcggacattg ccggcgttgt cgcctttatc cgcagcagag
    38101 gtctgcgaga acacatttct cacggcgacg agcgtactgt catcggcgca atcggcgacg
    38161 atagggtttt gagcgtcagg gaggtgcaga cgctgccgga ggtcgagaaa gccgtccgca
    38221 ttttggatac atggaaaacc gtcagtcggg aaaatcgggc ggaagacagc cgcgttgccg
    38281 ccaaaggcgt ggctttcggc ggcggggaaa ccgtccgtat cgccgcagaa ccgtcagtat
    38341 ggcgcaatgc ggatgcagtg tttctggatc cgtttttcac ttcggcaaac ttatacgaca
    38401 cttcaagtgc ggatgaaggg cggggacggt gcagacggtt ggcggaacag accgcatcgg
    38461 cgcatggcgc agggaaaccc gtattggtgc gcgtccgcaa cgtccgccat gtcgaagcgg
    38521 ctttgaatgc gggggcggac atcctgtatt tgggcggcgg gctgatgtcc gatcttgccg
    38581 tattgaatga agccggaagc ctgaacattc ccttggtgct gtgtaaagac aagcaccatt
    38641 ctgccgaaga ttggttgaat gccgcagaat atgtcgtctc gcgcggcaac cgccacctga
    38701 ttctgggcga gtcgggcgtg ttgagccata ccaaagacca tccctaccgt ttggatgtcg
    38761 aatccatcgt gaaagtccgc caaatcagcc atctgcccgt gattgcgaat attacgggat
    38821 tatggaaccg cgatatgccg caggaaatcc tgtacggctt ggcaaaggcg gcaggcgcgt
    38881 gcggaatcgt cggaacctgt tttgaaaagt cgggcggata gcaggcatac cggcagattc
    38941 aaaggcggag cagacattcg gacaacatgc cgtctgccgc ccgaatagcg gtgccgtctg
    39001 aagcgcacaa gacggtttca gacggcatat aatctgtttt ttattttggg aggagttcag
    39061 atggcacgac acgtttggca ggcaggacgg tttgaaatcg gtttggacaa gccgaaaatc
    39121 atgggcatcg tgaatctcac gcccgattct ttttccgacg gcggcgcgta ttcgcaaaac
    39181 gcccgaacag ctttggcgca cgccgaacgg cttttgaaag agggtgcgga cattctcgac
    39241 atcggcggcg aatcgacgcg gccgggtgcg gattatgttt cgtccgaaga agaatgggcg
    39301 cgggttgagc ctgtattggc agaagtggcg gggtggggcg ttcccgtcag tttggacacg
    39361 cgccgcacgg tgattatgga aaaagcgttg gcactcggtg gcatcgatat tattaacgat
    39421 gtggcggcgt tgaccgacga aggtgcggtc gaattgctgg cgcgccagac ggacacgggc
    39481 atttgcctga tgcacatgcg gggtttgcct gaaaacatgc agattaatcc gaaatatcag
    39541 gatgttgtcg gtgaagtggc gcggtatttg aaagcgcggg cggcggaatg catcgcggca
    39601 ggcatcgcac cgcaacgcat cacgctcgat ccgggtttcg gcttcggcaa aaccctgcaa
    39661 cacaatatcg cgctgatgag gcatttgccc gaattgatgg cggaaacagg ctttccgctg
    39721 ctgatcggcg tatcgcgcaa acgcatggta ggcgaactga cgggcgaaac cgacgcggcg
    39781 gcgcgcgtac acggcagcgt ggcggcggct gtggcggctg tggcgcgcgg cgcgcaaatt
    39841 gtgcgggtgc atgacgtgaa ggcgacggcg gacgcgttga aggtgtggga agcgttgggc
    39901 atcaatctgt aaacagcggt tcgcatactt catgccgtct gaaaaggacg gggcggcttc
    39961 agacggcatc aacggtgcag acagcagggc acaaacagac tgtataatct cggacaacgg
    40021 ttcacattct cggagcaaca catggcaaaa aaatatttcg gcacggacgg cgtgcgcggc
    40081 gaagtcgggc agtttccgat tacgcccgat tttgtattga aactcggcta tgcggcgggg
    40141 caggttttgg tgcagcacga caccgaccaa aaaccgaccg tcctcatcgg caaagacacg
    40201 cgcatttccg gctatatgct ggaagccgct ttggtggccg gttttacggc ggcgggtgtg
    40261 aatgtggtac agaccggacc gctgcccacg cccggcgtgg cttatctgac ccgcgcgttg
    40321 cgcctgtccg ccggcgtgat gatttccgcg tcgcacaacg cctattccga caacggcatc
    40381 aaattcttcg ccgaaggcgg cgtgaagctt tccgatgaaa tcgagttgga aatcgaagcc
    40441 aaaatcgacg aagaaatgaa aacccagcct tctgcacgcc tcgggcgcgc ccgccgcatc
    40501 agcggtgcgg acgaccgcta tatcgaattt tgcaaatcca cctttcccag ccattccgac
    40561 cttcggggtt tgaagttggt tatcgatacc gccaacggcg cggggtacgg tgtcgctccc
    40621 aaggtgtttc acgaactggg cgcacaagtc gtcagcatcg gcgacgaacc caacggctac
    40681 aatatcaatg aaaaatgcgg tgcgacttat accaagacac tccaggccgc cgttttacag
    40741 catgaagcca actacggcat cgccttagac ggcgacggcg accgcttgat gatggtcgat
    40801 aaaaacggta aggtttacga cggcgacagc ctgatttacg tcatcgctaa agcccgcgcc
    40861 cgagaaggta tcaacatcgg cggcgtggtc ggcacggtca tgaccaatat ggcgatggaa
    40921 aacgccctga aagagcaggg cgtcgatttc tgccgcgcca aagttggcga ccgctatgtg
    40981 ttggaacagt tgaaccaacg cggctggctc atcggcggcg aagccagcgg ccatattttg
    41041 tgcatggaca aacacaacac cggcgacggc attatttccg cgctgcaagt tttggcggca
    41101 ctgcaaacgc tgaaccaaga cctcgccacc gtttgcgccg attggcagcc gtatccgcaa
    41161 acgatgatta atgtccgtat cggcaaaggg caaaactggc aggaagcctc aaaagacgtg
    41221 ttggcggaag tggaaaaaga actcgaaggc aaagggcgtg tcgtgttgcg cgcttcggga
    41281 accgaacccg tcgtgcgtgt gatggtggag gcgcggcagg cggattgggc gcgcgacggt
    41341 gcggaacgta ttgcttccgc catcggcagc ctttaggcaa aatcaggcaa aaccgtttca
    41401 acagcggcgg ttttcctgtt taaatgccgt ctgaacgtcc ggcagagggc gcgaatctgc
    41461 cccttgccgc tttcagacgg cataatcttt gatagaatgc cgtttcgcgc agaaaatgtt
    41521 tcggcttgtt ctgacttttt atctccgaca atggaatatc cgctatgttt gcccttttgg
    41581 aagccttttt tgtcgaatac ggctatgcgg ccgtgttttt cgttttggtc atctgcggtt
    41641 tcggcgtgcc gatccccgag gatttgacct tggtaacagg cggcgtgatt tcgggtatgg
    41701 gttataccaa tccgcatatt atgtttgcag tcggtatgct cggcgtattg gtcggggacg
    41761 gcatcatgtt cgccgccgga cgaatttggg ggcagaaaat cctcaagttc aaaccgattg
    41821 cgcgcatcat gacgccgaaa cgttacgcac aggttcagga aaaattcgac aaatacggca
    41881 actgggttct gtttgtcgcc cgcttcctgc cgggtttgcg gactgccgtt ttcgttaccg
    41941 ccggcatcag ccgcaaagta tcgtatctgc gctttctgat tatggacggg cttgccgcgc
    42001 tgatttccgt gcccgtttgg atttacttgg gcgagtacgg cgcgcacaac atcgattggc
    42061 tgatggcgaa aatgcacagc ctgcaatccg gcatcttcat cgcattgggc gtgctggcgg
    42121 cggcgctggc gtggttctgg tggcgcaaac gccgacatta tcagctttac cgcgcacaat
    42181 tgagcgaaaa acgcgccaaa cgcaaggcgg aaaaggcagc gaaaaaagcg gcacagaagc
    42241 agcagtaaat cagattttcg accgtccgga cgcatttcgc gtttcaggcg gtctttgcat
    42301 tttcaggatg agccatgaaa cagaaaattt ttgtccttta taccggcggc accatcggca
    42361 tgacgcaaag cagcgaaggc ctgcgccccg ataccgcgct ggtcgggcag gcactcgcgc
    42421 cgttttcaaa cggcatggat ttcgattggc acgtttgtgg gacgctgatt gattcttccg
    42481 ccgtccaact gcaaaactgg tgcgcttggc tggacatcat tgccgccgcg ctgccgcagt
    42541 acgacggcgt tttggtgctg cacggtacgg acacgctcgc ctataccgcc aatctgttcg
    42601 ccctcgcgct gcagggtttg gacaagccga tcgtcctgac cggttcccaa tggtcgtaca
    42661 acgccgtggg cagcgacgcg ccgcgcaatc tggcgactgc cgttgccgca ttcccactcg
    42721 gattgaagca gacgcttatt gcctttgacg gcaaacttta tcccgccgtc ggcagcagca
    42781 aagtcagcac cgaaaccgcc tcaggcttcg ataatccgca tttcggtgtc atcgccgaat
    42841 gggatgaaac tcaaggctgg tacaatcttc gtattccgtc ccaagatgcg gcggccgttt
    42901 cagacggcct caaaatccgc tatcctgacc cgcaggcaaa aatcgccgtc cgcacgctta
    42961 ttcccggctt tgccgtccaa gaacttgccg acggactcgg acagcttccc gcccacgccc
    43021 ttatcctgca aagttacgga cacggcaaca cgcccgcaga cgaaggtttc atccgcgccg
    43081 tgcaagactt tacgcagcaa ggcaaactgc tgctcaacat cagccaagtc cgacaaggca
    43141 gaaccgctgc cgtttacgcg caaggcaacg cgttccgcaa ctcaggcatc atcaacggcg
    43201 gcaaatgcaa tttggaaaca gcaaccgcat tgatgacgct tgccgtttcc gaaggatggg
    43261 gcgcggaaga tgttcacaaa gaattagtaa gactaaagtt agtgtgaaac cggaatgaac
    43321 ttcaccgaca cccactgcca cctcgccgat cccgccttac gcgaaaacct gccgcacatt
    43381 ttgaccgccg cgcggaaagt tggggtgaag cggtttatcg ttcccgccac ctgtccgcag
    43441 gattggcaaa gcgtggcgga actgtcggaa atgccgtccg aacacggtca aatccgtatt
    43501 gcgctcggca tccatccttg gttttcagac ggcattgccg agcgtgattt cgtccgcctg
    43561 gaagcgatgt tggcacgtta tccgcaggca tgggtcggcg aaatcggttt ggatttttac
    43621 gacaaaaccc aaacgccgcc gcagcgcgaa cggcaaatcc aagttttcgt ccgccagctt
    43681 gccatcgcgc aaaccctgcg ccgccgcgtg attatccata atctcaaagc caccgccgac
    43741 atcgccgccg ccgtcaaaca gacaggcttt gcccaaggcg gcatcgttca cgccttctca
    43801 ggcagcgcgg aagaagcgcg cgtgttgacg aaactgggtt tcaaaatcgg catcggttcg
    43861 ttgttgctca atccgaacgc gcgtaaagtg cgcgatacgc ttaaagcctt gaacgacggg
    43921 gatttcgtat tggaaaccga cagcccgttt atgctgaaaa aagagattaa tacgcctgcc
    43981 aatattccgg gtattgcaaa gattgctgcg gaaatccgcg gaacctgtgt ggaagagatt
    44041 gccaaggtaa cggagcgcaa tgccgatgcc ctgttgggac ggtaggttat ccatctgaga
    44101 ttatcttttt gaatgtccgg aaaacctatt ataataattc agtgttgatg ccgtctgaaa
    44161 ttcaggcggc gtttgttatg gaagaattat gaagccgtct atcttagaaa aactgcaaca
    44221 actcggcgac cggttggaag aagttaccca ccttttaggg caacccgaag ccacatccga
    44281 tatggacaac taccgcaagc tcacgcgcga acacgctgaa ctgacccccg tcgtcgaagt
    44341 attccaaaac tatcaactgg cgcaaagcga tttggcggat gccgaagaaa tgttgtccga
    44401 ccccgaaatg aaagactttg ccgccgaaga aatcgaagcg gcgaaagcca aaatcggcgc
    44461 actcgatacc gaattgcaaa aactgctgct gcccaaagat gccgacgacg acaaaaacat
    44521 ctttatcgaa gtacgcgccg gaacgggcgg cgacgaagcc gcgctgtttg ctggcgattt
    44581 gctgcgtatg tacagccgct acgccgaacg caaccgctgg caggttgaaa tcgtgtccgc
    44641 caacgaaagc gagttgggcg gctataaaga agttatcgcc cgtattatcg gcttaggcgc
    44701 gtacagccgt ttgaaatttg aatcgggcgg acaccgcgtg cagcgcgtcc ccgccaccga
    44761 aagccaaggc cgcatccaca cctccgcctg caccgttgcc gtcatgcccg aagcggacga
    44821 actggaagac atcgagttga accccgtcga ccttcgcatc gacaccttcc gcgcatccgg
    44881 cgcaggcggt cagcacatca acaaaaccga ttccgccgtc cgcattaccc acctgcccac
    44941 cggcatggtg gtcgaatgcc aagacggccg cagccaacac gccaacaaag cgcaggcaat
    45001 gaaagttctc gccgcccgcc tgaacgacgc gcaaaaacgc gaagcccaag ccaaagaagc
    45061 cgccgaacgc aaatccctca tcggcagcgg cgaccgcagc gaacgcatcc gcacctacaa
    45121 ctatccccaa ggcagggtaa cagaccaccg catcaacctc accctgcaca agctggattt
    45181 tgtgatggac ggcgatttgg cagaaatcac cgatgccctg attgccgaac atcaggcgga
    45241 gcttttggcg gcaatgggcg attgagtttt gtgttttgaa atggaaatgc cgtgcatgca
    45301 atcaatttta atccaccata ttctactgat ttgtttgaat tcagtgtatt atgccgtttc
    45361 tcaaccatag acgacaactg gacatattga tgaagattgc gatttacggt acgaaaagct
    45421 atgaccgcga acattttacc cgcgccaacc ggcatttcgg cttcgagctg gagttttttg
    45481 attttatgct ggatgcgaaa acggcgaaaa tggcggaagg cgcggaagcg gtttgtattt
    45541 ttgtaaacga cgacggcagc cggcccgtgt tggaaaaatt ggcgcaaatt ggcgtgaaaa
    45601 ctgtggcgtt gcgttgtgcc ggcttcaata atgtggattt aaaggcggct gaagagttgg
    45661 gcttgaaagt cgtgcgcgtg cctgcctatt cgcccgaatc ggttgcggaa catacggtcg
    45721 gtctgatgct gactttgaac cgccgtatcc acaaagccta tcagcgtacc cgcgatgcga
    45781 atttttcgct ggaaggtctg accggtttca atatgtacgg caaaacggcg ggcgttatcg
    45841 gcacggggaa aatcggtatt gcaaccatgc ggattttaaa gggtttcggc atgaacctgc
    45901 tggctcacga tccgttttgc aaccccgaag cggaaaaaat cggcggcagg tatgtggatt
    45961 tggacgagct gtatgcccag tcggacatca tcacgctgca ttgccccgcc acgccggaaa
    46021 accactatat gctgaacgaa gcggcgttcg acaaaatgaa agacggcgtg atgattatca
    46081 acaccagccg gggcgggctg attgacagtg ccgccgcgat tgaggcgttg aaacgccgga
    46141 aaatcggcgc attgggcatg gatgtgtacg agaacgagcg cgagctgttt tttgaagaca
    46201 aatccaacga tgtgattacc gacgacgtgt tccgccggtt gtcgtcctgc cataacgtgc
    46261 tgtttaccgg tcatcaggcg tttttgacgg aagaggcgtt gggtaatatt tcggaagtta
    46321 cgctgtccaa tatccgcgag gtcggacaga tcggcgattg cggcaatgcg gttcgtgccg
    46381 acggctgacg tgttttaaaa gtttaaagga aatgctgtct gaaccaggtt tcagacggca
    46441 tttgacgttc aggcagcttg caaacttatt tcacttccaa cttggcaacg ccgcccatat
    46501 acggttgcag tgcggcaggg atgttgatgc tgccgtcggc gttttgatgg ttttccaata
    46561 cggcgaccag cgttctgccg acagccaagc cggagccgtt caaagtatgt accaagcggt
    46621 ttttgccgtt ttcgtctttg aaacgcgcct tcatgcggcg ggcttggaaa tcttcgcagt
    46681 tggagcagct tgagatttcg cggtaggtat tttgcgccgg cacccaaact tccaaatcat
    46741 acgttttggt tgcgccgaag cccatgtcgc cggtacacag ggtaatcacg cggtagggca
    46801 gttccaaagc cttcaggatg ttttcggcat ggccgaccat ttcttccagc gtttcgtatg
    46861 atttttcggg atgaacgatt tgaaccattt ccactttgtc gaactggtgc tggcgaatca
    46921 gaccgcgcgt gtctttgccg tacgaacccg cctcgctgcg gaaacagggc gaatgcgcgg
    46981 tcagcttcag cggcagttgt tcggacggga taatgctgcc ggcaacggta ttggtcaggg
    47041 taacttcagc tgtcggaatc agatattgcg tggttttgct ctcgtcgccg ccacgggtaa
    47101 cgtggaacaa atcttctgca aacttcggca gctgacccgt gccttgcaag gtggtgtcgt
    47161 ccacgatata gggtgtgtaa tgctcggtgt agccgtgttt cagcgtgtgc gtatcgagca
    47221 tgaattgcgc cagcgcacgg tgcaggcggg cgatttgtcc gcgcatcacg gtaaagcgcg
    47281 cgccggagag tttcgcgccg ccttcaaaat ccaaacccaa aggttcgccc aaatcgacat
    47341 ggtctttgat ttcaaagtca aattcgcgcg gcgtgccgac tctgcggact tcgacgtttt
    47401 cggtttcgtc tttgccggcg ggcacgcttt cgtgcggcag gttgggaatg cccgacaacc
    47461 acgcgtccaa ttctttttga acggcatcca aatcggcagc agcctgttcc aaatcggttt
    47521 tgatttgggc gacctgatcc atggccgcct gcgcctcttc gtgtctgccc tgacctttca
    47581 gtgcgccgat ttgcttggaa atgctgttgc gcgaggcttg cagctcttcg gttttcacct
    47641 ggacggcttt tcgctgctct tccagcgcat tgaaacgcgc ggcatcaaac tcgtaaccgc
    47701 gcgccgccaa gcgttcggca acggctgcgg tgttgctgcg gagcgattgg atgtctaaca
    47761 ttttctgatt cccgaataat ttgaaataca ttattgtaaa ccaaattcaa gatattttcc
    47821 tgagtccttc ccggttttga cacgcgtgcc gccgtgccgc ccgatttggc aaacacgccc
    47881 gatttgtggg aaaatcgcac gattgaactt aacggagggc gacaccgtgt tggacaggga
    47941 aggctatcgc cccaatgtcg gtatcatctt aatcaacaac cgaaacgaag tcttttgggg
    48001 caagcgcgtg cgcgaacatt cctggcagtt tccgcaaggc ggcattaagc cgggcgaaag
    48061 ccccgaaacc gcgatgtacc gcgagttata cgaggaagtc ggacttctgc cgcaacacgt
    48121 caaaatcgtc gggcggacgc gcgactggct gcgttacgac gtgccgaaca actgggtgcg
    48181 ccgcgaatgg cgcggctctt atcgcggaca gaagcagatt tggtatctcc tgcgcctgac
    48241 cggccgggat tgcgatgtca acctgcgcgc cacccgccac cccgaatttg acggctggcg
    48301 ttggcatcaa tattgggcgc ccgttgacga agtgattgat ttcaaacgcg acgtttactt
    48361 gggggcattg aaagaactct ccacccgctt cctgcgcggt atggaaagtt atgaagactt
    48421 tgccgcccgc caaccttccg acaaccgcta aaacaacgga acgcaacgct ttcaggccgt
    48481 ctgaaagcgt tgtttttctt actttcagat tattcctatg gctaaaaaca accaatacag
    48541 cgaatccagc atcaccgttc tcaaaggctt ggagccggtc aaagaacgtc ccggtatgta
    48601 cacccgcacc gacagcccga cacacatctg ccaagaagtc atcgacaacg cggcggacga
    48661 ggcgttgggc ggtttcgcga ctgcaatcga cgtgcaaatt catgaagacg gttcgctttc
    48721 cgtgcacgac aatgggcgcg gcattcccgt cggtctgcac cctgaagaag gcgtacccgt
    48781 ggtcgaactc gtgtttaccc gtctgcacgc gggcggcaag ttcaacaaaa aagacggcgg
    48841 cagcgcgtat gccttttcag gcggcctgca cggcgtgggc gtatccgtca ccaacgccct
    48901 ttccacccgc cttgaagtaa cggtcaaacg cgaaggcaaa atccaccgca tcgtgtttgc
    48961 cggcggcgac gtggtcgaac cgttggcaca agtgggcaaa tgcgccgtca aagacagcgg
    49021 caccgaagtg cgcgtgtggc cggacggaaa atattttgaa agcccgaatt acagcattcc
    49081 cgaactcgaa cgcctgctgc gtgccaaagc cgtgctgctg ccgggtgtgc gcgtttccct
    49141 gacccgtccg gtcaaaggcg aagacgaagc gcacacccaa acctggcatt accccgacgg
    49201 cctgaaaagc tatctgaccg acctgattgc cgacgcgcag gaagccgtac cgctgttctc
    49261 ttgcgaaaac tacatttcag acgaacacaa cggcgatttc agcatcggcg aaggcgccgc
    49321 ctttgccctg acttggctgg aagaaggctc gtgtgccaac gaaagctatg tcaacctcat
    49381 ccccaccccg ctgggcggca cgcacgaagc gggcttgaaa caagccgtgt tcaacgccgt
    49441 cagcaacttc atcaacctgc acaacctctt accgcgcggc gtgaaagtgc aaagcgacga
    49501 cgtgttcggc aaaactgcct ttgtcctctc tgcccgtgtc ctcgacccgc agttccaagg
    49561 tcagaccaaa gacaaactga ccaaccgcga cgcgctgaaa ctcgttgcta ccgtatcggg
    49621 cgaccctttg gaactgtggc tgaaccaaaa cgtggacttc ggcaaaaaaa tcgccgaact
    49681 cgccatccgt caggcacagg cgcggatgcg ttcggttaaa aagattgaaa agaaaaaagg
    49741 cagcggcgtc gccgtcctgc ccggtaagct gaccgactgc gaaagcgaag acatccgcga
    49801 aaacgaactc ttcctcgtcg aaggcgattc cgccggcggc tcagccaaac tcgcccgcga
    49861 caaagccacc caagccatcc tgcccctgcg cggcaaagtg ctcaacagct ttgaagtcca
    49921 ccccgaccaa ctcttcggca acgccgaaat ccacgacatt tccgtcgcca tcggcgtcga
    49981 tccgcacggt attaacgacc atcccgattt aagcggcctg cgctacggca aaatcgccat
    50041 cctgtccgat gccgacgtgg acggctcgca tattcaagtt ttgctgctga ccttattcta
    50101 ccgccacttc ccgaaactgg ttgccgacgg acacatctac gtcgcccagc cgccgctgtt
    50161 ccgcgtcgat gtcaacgcac aaggcaaaag caaacctgcc cgcaaattct acgccctcga
    50221 ccaaaacgaa ctcgacagca ttttggagcg gctgcaaaaa gaaggcgtca aagaaaccgc
    50281 ctattccatc agccgtttca agggcttggg cgaaatgaac cccgaccagc tcaaagacac
    50341 caccatgcac cctgacaccc gccgcctgtt gcaggtacaa atcccagaag gtgcagatga
    50401 cgagacgcgc gacatcttcg tcaaactgat gggcaaaggc gaagccgccg cccgccgcgc
    50461 ttggatggaa cgcgaaggcg atacggcgga attggatatt tgaaccgtga ttgccgcata
    50521 cgaaaaaatg ccgtctgaaa ccaaatcggt tttcagacgg catttcgttt ggggatttat
    50581 tctgctgcgg aagatccggc tgcttcggcg gcagcttggg cggactgctg ttgcaaagcc
    50641 tgctgcacga aaggatggtt ttgcgcgatc gcctgttctt cgggggtaac ttcgcctttg
    50701 aaacggttgt tcaaatcgaa acgtttgccg ccgcgcgcca aggctttcag ataacgcgga
    50761 cggcggcagt ggttggcgag gacgcgtgca atcagtgcgg aatcgtattg cggcaaagcg
    50821 gcaatcaaat cctgatcaat gccgagcgcc aacggtttga agcgtttgaa tacatcgtat
    50881 ttgccgtaga tgtggtcggc gatcatttcg gtctgtttct ttttgctcat agtttggacg
    50941 gcggatttca gtgccgcgcc caaagcggtt tcttgtgtca tttcggttgt attcctctaa
    51001 acaaacccgt gcgtcaaagc ggcacggcaa tgctcggtat tctattataa agtctgtgtt
    51061 ttggctaaat ttttatttgt ttgaaagggt aatgtcgggc gtattaacct gaacatccgc
    51121 attttgcgcg cgatggcgca gggcgtggtc gattaaaacc aatgccagca tagcttctgc
    51181 aatcggcgcg gcgcgcaagc cgacgcaggg gtcgtgcctg ccgtgcgtgg cgagttcgat
    51241 ggggttgccg ttgatgtcga tactgcggcg cggggtggcg atggagctgg tgggtttgat
    51301 ggcgatattg acgtggatgt cttgtccggt gctgatgccg ccgaggatgc cgcctgagtg
    51361 gttggacagg aagccttgcg gggtcagttc gtcgccgtgt tcgctgccgc gttggacaac
    51421 gctgccaaaa cctgcgccga tttccacgcc tttgacggcg ttgatgccca tcatcgcgta
    51481 ggcgatttcg gcatcgaggc ggtcaaaaac aggttcgccc aagccgacag ggacgttggc
    51541 ggcttcgata tgcagcttcg cgccgacgga atccaaggat ttgcgcacgc tgtccatata
    51601 gttttccagc tcggcaattt ggctatggtt ggcggcaaaa aaaggatttt gggaaatgtg
    51661 ttcgcagcct tcaaaccgga tttctttttc gccgacttgg gtcacgtagg cggtgatttc
    51721 cgtgccgaat ttttctttca accatttttt ggcaacggct ccggcagcaa cgcgggcggc
    51781 ggtttcgcgg gcggaactcc tgccgccgcc ccggtagtcg cgcgtgccgt atttgtgcca
    51841 ataggtatag tcggcgtggc cggggcggaa gctggtggcg atgttgccat agtctttgct
    51901 gcgctggtcg gtattgcgga ttaagagggc gatgggtgtg ccggtggttt tgccttcgaa
    51961 tacgccggag aggatttcga cttggtcggc ttcgcggcgt tgggtaacgt ggcggctggt
    52021 gccgggtttg cgccggtcga ggtcaaattg gatatccgct tcgcttaatt ccaagccggg
    52081 cgggcagccg tcgatgatgc agcccaaacc tgcgccgtgg ctttcgccga acgtggtcac
    52141 ggtgaagagt tgtccgaaag tgttgcctgc catattttcc ttctgtcggc ggtatgttgg
    52201 agacggcgga ttttagcata aaagttggag gaaaacgggt tatatgccgg taaaggggtt
    52261 gcgtgttttg cagtgaatcg gcttataatc cggtctgatt tttcaggata gcgatatgag
    52321 cgactacacg cagcagcttc aagataaaaa agaccacctt aaaacccttt ttgcaggttt
    52381 ggatgttcct gagtgggaag tgtatgaatc tccggacaaa cattaccgta tgcgtgccga
    52441 gttccgtatt tggcacgaag gcggtgaaat gttttacgcc atgtttgaaa aagggcagaa
    52501 ggctggcggg gcaagcctga tccgttgcga ccgcttcgat gctgcttcag aggcagtcaa
    52561 ttgcctgatg cctgaattga ttgccgttgc cgcccaatct gccgaactga gaaaccgttg
    52621 gtatgccgtc gaatttctgt ccacgctcag cggggaaatg ctggttacca tgatttacca
    52681 caaaaaactc ggcgacgcat ggcaacaggc ggcgcaagcg ttacagcaac agttggatat
    52741 ttccgttatt gggcggagca ggggacagaa aatagtctta aaacaggact atgtaacgga
    52801 aactttgaag gtcggcaacc gggatttccg ttatcggcaa attgaaggca gttttaccca
    52861 accgaatgcc gccgtgtgtc agaaaatgct tgaatgggcc tgcggtgcag cagaaggatt
    52921 ggatggggat ttgctcgaac tgtattgcgg aaacggcaac tttacgcttc ctttatctga
    52981 aaagtttgaa cgtgttttgg caaccgaaat ctccaaaacc tccgtcagcg cggcgcaatg
    53041 gaatatcgaa gccaaccgca tcggcaacat taaaatcgcc cgtctgtctg ctgaagaatt
    53101 taccgaagcc tataccagaa aacgtgagtt taaacgcctt aaggatggcg gtattgcttt
    53161 gacggattac gcattttcca ctattttcgt cgatccgccg cgtgccggca tcgatgagca
    53221 aactttgaag ctggtgtcgc agtttgacaa catcatctac atttcctgca atcccgaaac
    53281 gctgcgtgct aatttggaca ccttggtgga aacccatgcg gtcgaacgtg ccgccctgtt
    53341 cgaccaattt ccgtttacgc cgcatattga aagcagcgta ctgttgaaaa agaaaatact
    53401 ttgaaaaatc aagaggtaag aactatgtac cgacacatcg aatactatcc cggcgatccg
    53461 attttgagtt tggtcgaaac cttcaaaaac gacccgcgcc ctgaaaaagt caatttgagc
    53521 ataggcattt atttcgacga cgaaggcaaa atgcccgtgt tggaatccgt gagccgagcc
    53581 gaaaccgccc gcgccgccgc gcctgcgccg tcgccctacc tgccgatgga aggcttggac
    53641 acttaccgca gcgcggtgca gcatttattg ttcggcaaag acaaccctgc gctcgcgcaa
    53701 ggacgcatcg ctaccgtgca aaccttgggc ggctcgggcg cgctcaaagt cggagcagat
    53761 ttcctgcacc gctggtttcc tgaagcgcgc gcctacgtca gcgacccgac ttgggacaac
    53821 catcgcggca tttttgaagg tgcaggtttc gaggttggca cttacccata ttacgaccct
    53881 gccactgtcg gcgtgaaatt cgacgaaatg accgcgtttt tcaacaccct gcccgaaaac
    53941 agcgtcctga tcctccatcc ctgctgccac aacccgaccg gcgtggatat gtcggaacaa
    54001 caatgggacg aagtgttgca catcatcaaa acgcgcaaac tgattccgtt tatggacatt
    54061 gcctaccaag gattcggcgg cgatttggac agcgatgcct acgccgtccg caaagcggtg
    54121 gaaatggaat tgccgctgtt cgtcagcaat tccttctcga aaaacctgtc gctctacggc
    54181 gagcgcgtcg gcggcctgag cgtggtttgc ccgaataagg aagaagcgga attggtattc
    54241 ggacagctca aattcactgt ccgccgtatc tactccagcc cgcccgcgca cggcgcgtat
    54301 atcgccgccg acgtgatgaa cagccccgaa ctttacgcct tgtggcaaaa cgaggtttat
    54361 atgatgcgcg accgcatccg tgcgatgcgg cagaaacttt atgatgtctt aactgcgcaa
    54421 atccccgatc gcgatttcgc ttatttcatc aaacagcgcg gcatgttcgg ctacacagga
    54481 ttgagcgtgg aacaagtccg caggctgcgc gacgaatttg ccgtttacct gctggattcc
    54541 ggcaggatgt gcgtcgccgg actgaatacg tcgaataccg actatgttgc ccgcgcattt
    54601 gcggaagtct tgaaataaga gtttgaagta agtcaaaaga ccgtctgaaa aatatttatc
    54661 tttcagacgg tctctttata attggcgcac ccaacaggga tcgaacctgt gacctccagc
    54721 ttcggaaact gacactcttc caactgagct atgggtgcgt aaaacgtaag gttaacgtaa
    54781 attctgcaaa ttggcaaagg ttatcttgcg ccggcaggcg gcgtatggcg gcataaggag
    54841 agttttcttg aggataaaca attattttca aaggattatt tgttttatac agataccgtt
    54901 ggcaaatttt ttcatatttt caatgatagc gattggaaag accctgtgaa ttcagtataa
    54961 tccagcaaaa tattgttaac tgcgtttaac acaccaaact ataatttaca gcacaaccta
    55021 acctgacggc gaggcctacc aaatgaaaca actccgcgac aacaaagccc aaggctctgc
    55081 actgtttacc cttgtgagcg gtatcgttat tgttattgca gtcctttatt tcctgattaa
    55141 gctggcgggc agcggctcgt tcggcgatgt cgatgccact acggaagcag caacgcagac
    55201 ccgtatccag cctgtcggac aattgacgat gggcgacggc atccccgtcg gcgaacgcca
    55261 aggcgaacag attttcggca aaatctgtat ccaatgccac gcggcggaca gcaatgtgcc
    55321 gaacgctccg aaactggaac acaacggcga ttgggcaccg cgtatcgcgc aaggcttcga
    55381 taccttgttc caacacgcgc tgaacggctt taacgccatg cctgcaaaag gcggtgcggc
    55441 agacctgacc gatcaggaac ttaaacgggc gattacttac atggcgaaca aaagcggcgg
    55501 ttctttcccg aatcctgatg aggctgcgcc tgccgacaat gccgcttcag gaacagcttc
    55561 tgctcctgcc gatagtgcag ctccggcaga agcgaaggca gaagacaagg gtgcggcagc
    55621 ccctgcggtc ggcgttgacg gtaaaaaagt cttcgaagca acctgtcagg tgtgccacgg
    55681 cggttcgatt cccggtattc ccggcatagg caaaaaagac gattgggcac cgcgtatcaa
    55741 aaaaggcaaa gaaaccttgc acaaacacgc ccttgaaggc tttaacgcga tgcctgccaa
    55801 aggcggcaat gcaggtttga gcgatgacga agtcaaagcg gctgttgact atatggcaaa
    55861 ccaatccggt gcaaaattct aaatttagat taaaatttcg gattaaataa aaacggggca
    55921 ggtatctgct ccgttttttt atgggaattt atagtgaatt aacaaaaatc aggacaaggc
    55981 gacgaagccg tagacagtac aaatagtacg gaaccgattc acttggtgct tgagcacctt
    56041 agagaatcgt tctctttgag ctaaggcgag gcaacgctgt actggttttt gttaatccac
    56101 tatatttgtt tgtccgtgtg gaaatgacat caaagggtgt gaataggctt ttcatctttg
    56161 aaatctgttt gcacgatcgg atgaataaaa agtaggatga taaaaaagct gatgtatgga
    56221 tactggttta actcatttgt tttaaagtta tagtcgagat acgtgtattg gtgcaactgg
    56281 tttgccgttg atgaaaatgc cgtctgaaaa tgtttcagac ggcatttttt aagatatcaa
    56341 cagtcagtct tcataatttt ccatcggtgg gcagctgcac acgagattgc ggtcgccgta
    56401 cacgtcgtcc acgcggttga cgaagggcca aaacttgtgt tcgcggacga acggcaacgg
    56461 gaagacggct tcttcgcggg aatacggatg cgcccagttg ccggttatat ctgcggcggt
    56521 gtgcggcgcg ttgaccagtg ggttgtcgtc tttcggccat tcgccgcgcc cgactttcag
    56581 cacttcctgt ttgatttgtt tcagggcggc gatgaagcgg tcgagttcgg ctttgctctc
    56641 gctttcggtc ggttcgatca tcagcgtgcc ggcaacgggg aaggagacgg tcggggcgtg
    56701 gaagccgtag tccatcaggc gtttggcgat gtcggtttcg gtaatgccgc tttcggcttt
    56761 gagcggacgc aagtcgacga tacattcgtg cgcgacgcgg ccgtttttgc cggtgtagag
    56821 aatcggataa tcctcgccca aggctttggc gacgtagttg gcgttgagca atgcccagcg
    56881 cgttgcctgt tccatgcctt gtttgcccat catggtcagg tacatccaag taatcggcag
    56941 gatggatgca gaaccatatg ctgcggcagc cacggcggtt tgatcggcag ccgcgttgtg
    57001 ggtgtcggtc aaggtatggc ccggggcaaa cggagccaaa tgggctttca agccaatcgg
    57061 acccatgccc gggccgccgc cgccgtgagg gatacagaag gttttgtgca ggttcatgtg
    57121 caacacatcc gcaccgactt cggcaggctg catgatgccg atttgggcgt tgaggttcgc
    57181 accgtccatg taaacctgtc cgccgttttc gtgaataatg cggcagatgt cgcggatgcc
    57241 ttcttcgtac acgccgtggg tggacggata ggtaatcatg atggcagaca aagcgtcgcg
    57301 gtgttgctcg gctttggctt tcaaatcgtc aatgttgacg ttgccgtgtt cgtcggtgtc
    57361 gacgacgacg actttcaaac cgagcatggc ggcggtggcg gggttggtac cgtgggctga
    57421 ttttggaatc agacagatgt tgcggtgcgc ttcgccttgg gattcctgat agcggcggat
    57481 ggcgagcata ccggtgtatt cgccttgtgc gccggaattt ggttgcaggg aaatcgcgtc
    57541 aaagccggtg atggctttca ggctgttttc catatcggcg agcaattcgc ggtagccggc
    57601 ggtttgcgct tcgggagcgt aaggatggat gtcggtgaac tcggcccaag taatcggcaa
    57661 catttccgca gtcgcgttga gtttcatagt acagctgccc aatgaaatca tactgcggtt
    57721 catcgccaag tcgcggtctt cgagtttttt cagataacgc aacatttcgt gttcggtgtg
    57781 gtaactgttg aacacaggat gttgcagaat gtcgtcctga cgcagcaatt cggcgttcag
    57841 acggcctttg acatcatcgg caaatgtaaa cgtatccttg ccggtaaacg cgcggtacaa
    57901 atcgaccaaa tcttcgtatg ccgatgtttc atggaatgca gccgcaactt gagtatcgtt
    57961 gacgcggcgc aggttgtaac ccgacgccaa agcagcggca aacacttggt ctgctttctc
    58021 tttactgcca aaatcgatgg taacagtatc gaaaaagact ttgtgaacca cattcaggcc
    58081 gtctgaaacc agcgcatcgg caaaggcaga agccagcgcg tgaatgcggt tggcaatgcg
    58141 tttcacgcct tcagggccgt ggtaaacggc atacataccc gccaaattcg ccagcaatgc
    58201 ctgcgcggta caaatattgg atgtagcttt ttcgcggcgg atgtgttgct cacgggtgga
    58261 caaagccatg cgcaaggcag gtttgcccga tgcgtctttg gatacgccga tgatgcggcc
    58321 cggggcggaa cgtttgaact cgtctttaaa cgcgaaataa gcggcgtgcg gcccgccgaa
    58381 gcccatcggc acgccgaagc gttgtgtgtt gcccaacgca atatccgcac ccaattcggc
    58441 aggcggtttc agcaaaacca agctcatgat gtcggcggaa acggcgacaa tcgtgccttt
    58501 ggctttcaga cggccgataa cgtcctgcaa gtcttgcacg tcgccgtctt tgccgacgta
    58561 ttggaacagc gcgccgaagt attcgccttc gtcggcttgg gcaaaatcgc cgaccaccag
    58621 ctcgaagccg aaatacttgg cacgggtttt catcacgtcc aaagtttgtg gatacacgcg
    58681 ctcgtccaca aagaaacgct cggattttac cttgcccacg cggtgcgcca tcgccatcgc
    58741 ttcggcggcg gcggtcgctt cgtccagcaa agacgcgccc gccacaggga aaccggtcaa
    58801 atcgatacac acttgttgga agttcaacaa agcttccaaa cgaccctgcg cgatttccgc
    58861 ctgatacggc gtgtaggcgg tgtaccaacc cggattttcc aatacgttac gcaaaatcac
    58921 gttcggcacg cgggtcgggt aatagcctaa accgatatag gatttgttga tcatgttttt
    58981 cgacgcaatg cctttcaatt ttgccaacgc gtccgcttcg gtcagggcat cgggcaaatc
    59041 gagttcagac ggcatacgga tgctttgcgg cacggtgttg ccgacaaaat cgtctatact
    59101 tttctcgccg acagcggcaa gcaacgccgc ttcgtcgcca aaactcaaat gccgcgcggc
    59161 aaattcgtcg gggttgaaca gttcggacag tttcatttct actccttcgg gtttgtaggg
    59221 ctgccatcag gcagaatttt tagacatcgg atgattcggg caagggtagc acaaaagacg
    59281 ggataatggc ggacaatgcg ccagaatgca gcaggtcagg acaagcagcg ccacaagcgg
    59341 cagcgataag ggaaagccgc cgcccaaaac catgaaacct gcaggcacca gccaagctaa
    59401 gggatgcgcc ggaagcggaa aaacaatatt gagcagaacc aaaatcacga caaacagcgg
    59461 cagacccgcc atcaggttgg cacgcctgta tgttgcgtac gggtcggatg cttcttcagg
    59521 ttcgcaatat tccatgattt cagcctgtcc gggctttatc cacagcaggc tcggacggtc
    59581 ggtcatgccg tctgaaccgg caggccgtct ttttcaaaaa acgccatacc gctgcaactt
    59641 catgcggctg tatggcgtag gctttgcact tcagacggca tatgcgtccc gaagcagttt
    59701 ggtgtcccag tcggttcatg attatataaa caacttgggt gcggataaac ctttgtttat
    59761 ctaaacccct gttttctcaa aaattgattc aaatcttcgg caaatttccg atagcctttg
    59821 ccgttggcgt ggatttggtc ggatttcaga ttattatcgc ccaaaatttc cgcccacgcg
    59881 ccgccgaaca gcggaatgcc gtattcctcg gacaaatcct catacagcgg atggtcgctc
    59941 aaatgtccga acaacgcgcc cagtgtgatg tgcggcacgc cgacgaggac ggcggggatg
    60001 ttttccttct gcacggtttc gatgattttc gcgatattgg cgcgggtctg ctcctcggga
    60061 actttgcgca gaaagtcgtt gccgcctatg ccgacaagca caagcttggg tttgcgtgcc
    60121 aacagcgcgg gcaggcgcga cagggcttgg gcggatgtat cgcccgatac gccgccgttg
    60181 acaatattcc aacccgtcag tttttgcagt tgcgcggggt aggattcgcc agggtttgcg
    60241 ccgtagccga aggtaagcga atcgcccaag gcaagtacgg tgcttccttc gggaattttg
    60301 gcgtgggttc gggcggattt tctgccgcag gcggtaagca gcaacgcgcc tgcaccgagg
    60361 aggaagattc ttctgttcat tggtttttca gacggcatcg agccatttcg ggtggtattt
    60421 cagggtttta cggtaaaccg gacagctttc ggcgtgcgcg cctttgaggt agccggtact
    60481 catcagaaat tcgccgacga tttcgccgcc gacaaatttg aaatgttttt taaagagttt
    60541 gacccattcg tctttgcttc gcggatggtg cgcgtcgagc cagttcttga acgagccgta
    60601 ttcttgttgc aacgcttgga tttgccgtgc attgaaaatg gcggcatcga ttttcaggcg
    60661 gttgcggacg atgcccgcgt cggcaagcag gcgttcgcgg tcggtgtcgt cgaaggcggc
    60721 aacggtattg atgtcgaacc cttcaaatgc tgtctgaaac gcctgctgct tcttcagcat
    60781 cagcgtccag tttaatcctg cctgattgat ttccaacacc agccgctcaa acaattcatt
    60841 gtcgtcctca atcggaaaac cgtattgcgt gtcgtggtaa tgtttgttcg ggttgtcggt
    60901 gttttcggga agtgaggcgg caaattcgca atagttcacg ttttactcga ccatctgttg
    60961 cgccgcctgt ttcagtccct gttcgagtgc ggcggtcatc gcggcgtagc cgtcaccctg
    61021 ctgttcggtt tcgatatgga agggtctgtt cataccgtcg ggtaggacgg cgtagccgct
    61081 gatgagggtt ttgcccgtgt agctgccttg gaatgcgtcg atatagaccg tccatttttc
    61141 ggtactgccg ctgcgtgagg caggaacaaa gatgcgtgcg ctgtccaaac ggttgaatgc
    61201 attgctcaac gccgcttcga gcatatcgtc caaagtgtct gcccaaacgt ggttttgtgc
    61261 ggtgttgagg cggtaggggt cggtttgata gaccagtccg ccgcgtttga gcggttcggc
    61321 aaggcggact tcgacggcgg tttcgccgcc ttgcgttgca gggcggatgt agcggctgtc
    61381 gggcaacacg aaatattgtg tgctttgcat agtaccgcag gcggcaagcg tcagggcggc
    61441 ggcgatgggg aaaaggcgca ttatcggctt cctttcggga tagggtcttt gctgctgctg
    61501 ttgaaaatca gcgcgttggg tttttctttc aaagtgttaa tgacgggttg aacgtctttt
    61561 aaggttttgt ccaaactttg cagcgtattt tgtacgtcgc cgtagatagg cgattgcggc
    61621 gatacgcctt gcagggtttg acgcaattct ttcagggttt ggttcagttc gttcggaatg
    61681 ttttgcgttt gcggtttgcc gaccagtttg tcgatagagc ttagggcggc attggcagat
    61741 ttgagtgtgg acttgagctc ggtaagcgaa ccgttcaatt cggcaaccgt cttatccaaa
    61801 ggcagtttgt cgaacttgtc cagcaaatcc gccagtttga cctgcaagtc gtccaaaccg
    61861 ccgccccgtg tggcgatgac ggtatcgcct gcataaacgg tatgcggtcg cagcttgggc
    61921 gaggcggaag gctgatcgtt caactcaatc attttgctgc cggtcagcag gttgttgctg
    61981 gagatggtgg cggtcaggcc tttgtttaag gccgtctgaa attgttgttt ccaatgttct
    62041 ttgctttgtt cgtcggcatt gatttccaaa cgggaaggct caatacggat gcgtacggga
    62101 atccagccgt tttcaaacag gtgcaggctg tcgttgcggt cgaaataagg aacatcggaa
    62161 accacgccga cattcagccc tttgtactcg acaggcgaac cgacggtcag tccgcgcacg
    62221 gattgtttga aaaacgcggt gtagtacagc gaacggtcat caggcaggtt ggcgacttcg
    62281 ctgcggctgt cgtaaagcgt gaagctgtcc tcgcttttga cgtttttact gtttttggtt
    62341 ttcggcgaat caaatgaaat cgcgcccgac agcagggcag gcagaggggc ggaattgagt
    62401 ttgatgccgc tgcctgtggt ttcgatattg atgccgcttt ccagccaaaa acggctggcg
    62461 gaatgaatca gtttgtcgtt ggggctttgg atgaagatgg tgtaatgcac gctttggtcg
    62521 gacgggtcga aatgcgcgct ttcgacttgc ccgaccataa agttttcata caaaacaggg
    62581 ctgttgacgt tgaggatgcg gtcgttttta ccaatcaaat tcaagcgcag cccgctttgc
    62641 ccgatggcgg taacgggcgg aatgtcctgc acttggaaca cgtcttttgc ctcgtcgctt
    62701 ttgccgggtg taaaggcgat gtacgaaccc gaaagcagcg tacccaaacc ggttacgccg
    62761 ctttggtcga tacgcggctt gaccacccaa aactgggtat cgctgcggat gaggccggat
    62821 acgtccgcat tgagttgggc ggttacttcc acgccttttt ggtcgtcgcg cagtttgatt
    62881 cgggtaacgc gtccgacatc gatgctcaat actttgatga ccgtattgtt gacctcaatg
    62941 ccttccgcgc tgtccatcaa gagcgtaacc acaggtcccc tgttgcggat ttccttaacc
    63001 caaagccagc cgccggcaat cagcgcaatc agcgggacca gccagacggc ggagaggaag
    63061 gtgttgtttt tacggacgcg agcttgagcg tgtccgtttg gaggagggct gttgtcagtc
    63121 atatttttcc gtttcattga aagcaatgcc gtctgaagcg cgtttgtccc aaagcaggcg
    63181 cgggtcgaaa taataggcgg acagcatcgt cagaatcacg accaggcaga aatagactgc
    63241 cgcactgccc ggaatgacgc gcgcggcata agtgtggaac gaacacatca aaataataat
    63301 cacaaaaata tcaatcatcg accagcggcc gatggattcg gtgatccgat ataaaaccga
    63361 catcttgtcc gcgctcatca cgggtttgaa gtatgcggaa taaatcaaaa ccgccatcgc
    63421 aataatcttc aaaaccggca ccataatact ggcactaaag ataatcacag caatcaagcg
    63481 gtcgccgtcg tcccacatat aaacaatgcc gttgaaaatc gtattgatct ccaaagccgt
    63541 cgggttggac gaaatcataa tcggcaggat gttggtaggg aaatacagga taaacgccgc
    63601 aactaaaaac gccagcgaga tgctcaggct tttcgggcgg cgacggtata agtccgcacc
    63661 gcatacgccg caaggttgct catctttatc gcggaaatac aggcagcggc tacaacagat
    63721 tttgtcttca gtgaccgtct gaaccgcatt atcccccgtc agccgcccga tttgaaaata
    63781 cacccaatgc tggggaactg ataccgaagt ccgaatcagc ataaccgaca gcgcgaacat
    63841 cagataaaac gccggcccga agcgaacctc tgccacagac gagagcttga tatacgccac
    63901 cagagtggaa acaaaaaaca catccaccat catcgcctgc ctcaagcgca ccattacgcg
    63961 cgttgccaaa cgcagcgcag gatacacccg tttccgtatc agcgcggcat agacatacag
    64021 gcacagcaaa aggaacagaa ccggcgcgcc gaaggtcagc acaaacatca cttcggccaa
    64081 aaagccataa tcctgaaaca ccatcaggcg catcatctcg ggcagcgaaa ggacggatgc
    64141 cgcacccggt atcccgacct cgatatacgt cataccgtaa gcaaacgcca tcaaaatcag
    64201 cgaagccgcc gcataagcgg gcggggcgga aaaaggatgc ctgcccaccc tgaagagctt
    64261 atagccgcag cgcgggcaga acgccgcctc ccccctgtcc aaccgaggca catccgcgcg
    64321 gcagccgcat tccgggcaat ctaccgtatg cggcggcagg gcttcatcgc ggcagttgcc
    64381 gcgaaggctg tgggggatat tttcggcaaa cggcttcatc gggaaagtgg caaatataag
    64441 tggcggcatt ataaaggaaa aaaagcgata cacccaatca ggatgcaaaa ccggcaggtt
    64501 cggcagtatg aacaaaccct tggtgtccgg aaatatgtga taataaattt cgtttatgat
    64561 tctttattat ttttatagtg gattaacaaa aatcaggaca aggcggcgaa gccgcagaca
    64621 gtacaaatag tacggaaccg actcacttgg tgcttcagca ccttagggaa tcgttctctt
    64681 tgagctaagg cgaggaaacg ccgtactggt ttttgttaat ccactatata tgcgggcaag
    64741 tgcggatttt gcccgcaccg catccttatc ccttaccgac aaaggaaaaa atatgagtga
    64801 aaccgaaaat caagccctga catttgccaa acgcttgaag gcggatacca cggcggttca
    64861 cgacagcgtg gataacctcg ttatgtctgt ccaaccgttt gtcagcaaag aaaactacat
    64921 caaatttttg aaactccaat ccgttttcca caaggctgtc gaccacatct ataaagatgc
    64981 cgaattaaac aaagccattc ccgagctgga atacatggct cgatacgatg ccgtaacgca
    65041 agaccttgca gatttgggtg acaaacctta cgaatacggc aaaccgctgc cgcatgaaac
    65101 cggcaacaaa gcaatcggct ggctttattg cgccgaagga tccaatttgg gcgcggcatt
    65161 tttgttcaaa cacgcccaaa aactcgatta caacggcgaa cacggcgcgc gccacctcgc
    65221 tccgcatccc gacgggcgcg gcaaacactg gcgcgccttc gtcgagcatc tgaacgcttt
    65281 gaacctgact cccgaagccg aagccgaagc catccaaggc gcgcgcgaag cctttgcatt
    65341 ttacaaagtc gtgttgcgcg aaacctttgg cttggccgct gatgccgaag cgccggaagg
    65401 aatgatgccg cacaggcatt gagtaatgca aaaatcaggt atcggtgttt ttatggagtt
    65461 gcgctttata tgatacgcag ctgtttgccg gaacatattt gcaaccgact atgaaaactt
    65521 gaaatttttt ttcaataaat ttatgaataa gcatcatgcc ttttcgtaaa agaggatgaa
    65581 cttatttttg ttatccatgt cattaggaga atgttatgtc gaattcgtca tttaaattga
    65641 gtgcacttgc catcgcctgc ggtctagctc tttcagcttg tagttcggga ggcggagacg
    65701 cgccaagtgt taagcctacc ccgactgttc cgggtgcatc aaacccggcg cctgccaatc
    65761 ccgaaccttc agcaccggct gcctcaccat tgaaaaccgg tgagttgggt gaaaaatatt
    65821 tttacgggga aggtgaaatc acgaagctgg tcatcaatgg cgaaactatt aatttgacag
    65881 tggctgatga acagctgtca aggagggtga agctttggac agacttcgat aagattatta
    65941 cttcccaagg ttttgaaaat cttatttatg gtgcggctaa attggcagat ggttcatacg
    66001 cactctttgt gcaaggaaag ttgagcgaca gtctgcccgg cgatacggtt acttatagcg
    66061 gcgatgtatt gcatttccgt tcgcgcaact tgaccgaagg taattggttt aatgaaggta
    66121 attcattccg tgcagccggt tcgtttactg ctactgtcaa ttttgccggt aaatccctga
    66181 acggtaagat taacagtggt gacggattgt atatgggtac ctaggaattc gagggaagtc
    66241 ttgatggcaa ccgctttacc ggtacttgga aaaacggtga gaaaggtagt atctctggag
    66301 gattctatgg tgccaaggct gcagaaatgg caggcaggta cagctatgtt aaggatgaac
    66361 caaaacaggc caagacatat acaaataaca gcttcggcgt atttggtggt aagaaaaccc
    66421 aataatcccg tttgaatcct tgatttgacg aaagccccgg tgcggataga ccggggcttt
    66481 tgtttgatat tatatggtta ggatgacgga aagtgataat atagtgaatt aaatttaaac
    66541 cagtacagcg ttggctcgtc ttgctgtact atttgtactg tctgcggctc gccgccttgt
    66601 cctgattttt gttaatccac tatatatccg tataccttgc tgctacagtg ttacagtcac
    66661 agccggagtg ggatgttgaa ggaattgccg gtaaagcctg aaaaaatgcc gtctgaaaac
    66721 gggtttcaga cggcattttt tgattgccga tatgttaacg gacgacattg gcgcgcatga
    66781 cgacgcggac gtggaacgag cctgcctgac agtcgtattg cccgccttgc agcggttgct
    66841 tgtcaaagta gctgtggaag ccggtaacgc cgcgtccgcc gagtttgcct gcggtctgtt
    66901 ggaatttgcg ggcggcattg attagggcgc gttcgtaggc ttctgagtcg gatttgccta
    66961 tgccgtttgc cgcctgacgg gtaactagat tcctgccgtt tgcaaccggt acgcccccgc
    67021 cgccgaagct gacgggaatc cctgattcca atacgccgtc tgcaatggct gcatttattg
    67081 ccgcctgacc gttgcagcaa cggtaaatga tgtttttgcc gcttcctgcg gtgtcgcccc
    67141 ggatgacttt gcatgattct ccggccggtg tgccggggga tgccgtgtgc gcgtttttag
    67201 gtgcgctgcc ggattggcag gctgccagca tcagggcggc ggcggagagt atgaggattt
    67261 tttttcatgt cggatatcct tgcttgcggt gggaaatcat tgccattgta ccgtaagatt
    67321 caacaaaatg ccgtctgaaa acggggttcg gacggcattg tggctcaggg gttcaatacg
    67381 cgtgcgatga gggctttttc tttgccccgc atattgggga ttttgacctg gatgccgttg
    67441 ccgggtgcaa catcgacagg ctggcctttt cgggccattt gttccaattt gatggtttgg
    67501 ttgccgctcg ggtggatgat ttcgagcgaa tcgccgatgg caaagcggtt tttaacttcc
    67561 accgttgccc aaccttcagc gtcgatttcg gtaacgtggc cgacatattg gctttgtttg
    67621 gcgatggagt ggccggtcag gtagttttga tagtcttggg tttggtggcg ttcgaggaag
    67681 ccgctggtgt agccgcggtt ggcgaggcct tcgagttcgc tcaacaggct gtaatcaaac
    67741 ggacggcctg caacggcatc gtcaatcgct ttgcggtagg attgagccac gcgtgcaacg
    67801 tagtagagcg acttggtacg gccttcgact ttgaggctgt ccacgccgat tttggcgagt
    67861 ttctcaacca cttcaatact gcgaaggtct ttggagttca tgatgtaggt gccgtgttcg
    67921 tcttccataa tcggcatcat ctcgcccggg cggttggact cttcaatcag gaaaactttg
    67981 tcggcgtagg gatggcgttt ttgaccgttg atgccttcaa agttttggtt ggcttcttct
    68041 tgggcttttt caaagttgaa accttgcaga agctgggcat cgcccgcatc gctttccgta
    68101 gcgttgtgga ctttgtagtc ccaacggcag gagttggtgc aggtgccttg gttggggtcg
    68161 cggtggttga agtagccgga gagtaggcaa cggccggagt aggcgatgca caatgcgccg
    68221 tgaatgaaga cttcgagttc gatgtcgggg cattgttggc ggatttcggc gatttcttcc
    68281 atactcaatt cgcgcgacag gatgatgcgt tcgacgccga tattctgcca gaatttcacg
    68341 ccccagtagt tggtggtgtt ggcttgtacg gacaggtgga tcggcatttc cggccatttt
    68401 tcgcgcacgg tcataatcaa acccggatcc gccataatca gcgcgtcggg cttcatcgca
    68461 atcaagggct ccatatcgga gacgaaggtt ttgagtttgg agttgtgcgg cagcgtattg
    68521 acggtaagga agaatttttt gttgcgctcg tgcgcttctt taatgccttg ttcgagaacg
    68581 tcgagtttgg caaattcgtt gttgcgggcg cgcagtgagt aacgcgggct gccggcgtaa
    68641 acggcatctg cgccgtaatc gtaggcggcg cgcattcttt ccaatccgcc ggcgggcaat
    68701 aagagttcgg gtgctttcat cgtgtttcct tttcggttga aaccccgccc tttagggcgg
    68761 tagaatcaga ctttatttgg gaggggtgta accctttccg aatcagggca acatataggg
    68821 cgacgcttta tgtgtcgtcc tgtgtgttga aacatgattt gtgtgctttg taaaaatgtt
    68881 tcagacggca ttgctgcaaa tgccgtctga aaagggtttg aggatgggcg gattatccgc
    68941 cttttcgtgt tcgcggtcaa ttttgccggg aaatttataa ggatttatca agtatttgcc
    69001 tgattgggat acaatgcggc agtttgaatg cgagagagaa tgtgatgaat cctaaaatcg
    69061 tgtttttcga tattgacgat acgctgtacc gcaaatatac ggataccttg cgtccttccg
    69121 tgaaaacggc ggtggcggct ttgcgcggca aaggcatatt gacggcgttg gcaacggggc
    69181 ggtctttggc gacgattccc gaaaaggtca gggacatgat ggcggaaacg ggtatggatg
    69241 ccgtggtaac gataaacgga cagtttgcgc tgctgcacgg taaaactgtg cgcgaagtac
    69301 cgatggatgc cggtttgatg ggcagggttt gcgcgcattt ggatggcttg ggcatggatt
    69361 atgcgtttgt cggcggagag gggatcgccg tgtccgcgct gtcggaatgc gtgtgccgcg
    69421 ccttgcagca tatcgccagc gatttttttg ccgataagga ttatttttca agcaaaccgg
    69481 tgtatcagat gctggtgttt gcggaggaaa acgaaatgcc gccctggtcg gatattgtgg
    69541 aacgggaagg cttgaaaacg gtgcgctggc acgaggaagc ggtcgatctg ctgcctgcgg
    69601 gaatgtcgaa aacagacggc atcagaagcg tggttggggc attgggtttg gaaatggcag
    69661 acgtgatggc gttcggcgac ggtttgaacg atgtggaaat gctgtcagaa gtcgggttcg
    69721 gcgtggcaat gggcaacggg gaacaggcgg cgaaagaggc ggcgaaatat gtttgcccca
    69781 gcgttgatga ggacggtgtg ttgaggggct tgcaagattt gggcgtgatt tgaacgcata
    69841 ataacaaccc tgccggtttc agacggcagg gtcggttttc agcccttcat acagccttcg
    69901 ttttgaagca gggtaaataa gggcgcgccg cttgcacgga tattcttgcc gccttgaagg
    69961 tcggtaaatt ccaaaatggc ggcggcttcg acaatttccc cgccgagttt gcggatcagc
    70021 tccagtccgg caagcatcgt gccgcccgtg gcaaccaaat catcgaccag cagcacgcgc
    70081 gaaccgggtt tgacggcatc ggtgtggatt tccaccgcag cttccccgta ttcgagcgcg
    70141 tagctttgcg atacggtttc aaaaggcagc ttgccttttt tgcggatggg gacgaaaccg
    70201 acgttgagct ggtaggcgag tgccgcgccg ataatgaagc cgcgcgcgtc caaaccggca
    70261 acgatgtcga ttttctgatc catatagcgg taaaccaata aatcaaccaa aagttggaag
    70321 tattccgcgc tttgcaggac gggcgtgatg tcgtggaata agatgccttt ttgcggccag
    70381 ttttcgattt tgcggatttt gtcggcaagc gcgccgacac tcatagcttc gggatgaacc
    70441 agcattgcgt gttccaagtt tgatgttttt aacgccatat tgtagccgtc agcctgccgc
    70501 ttgccaaatc aatcaaaaca atagcggcaa aatatgggca tcggcaaata ggaaaccgag
    70561 tgtccgttgt gatacaatcg gctggaaaat atacaggtaa aaaatatgtc cgcttatcga
    70621 aaaggcaaca tctttatcat ttcggccgct tccggcacgg gcaaaaccac gctggtgtcg
    70681 cggctgttgg caaaccataa cggtttgcgc gtttccgtat cgcacacgac gcgtccgccg
    70741 cgtgaaggcg aagtaaacgg cgtacattat cattttgttt ctaaagaaga gtttgagtcg
    70801 cttatcgcgc aggaagcttt tttggaatac gcagacgtgt tcggcaacta ttacggcaca
    70861 agcgcggagg gcgtgaatgc tttggcggcg gcaggctatg acgtaatttt ggaaatcgac
    70921 gttcagggcg cggcgcaggt tcgcaacgcg ctgccggaag ccgtcggcat ctttatcctg
    70981 ccgccgtctt tcgatgtgct tgctgcacgt ctgaacggac gcgggacgga cagtcgggaa
    71041 gttatccaaa ggaggctgtc gaaggcaagg catgaaatcg aacagtccgt attgttcgat
    71101 tttgtcgtgg tcaatgatga cttggcgcgg gcggaggagg atttgcgcca tattgtgaat
    71161 gcctgccgtc tgaaaaggtc gcggcaactg ggatttattg cagatttgtt ggaaaattcc
    71221 taaaaaaccg cgaaaatacc cagtttccta ttttaaatat ttttgaaaga aagcaaataa
    71281 tatggcacgt attaccaccg aagactgtac cggaaaaatt tccaaccatt ttgacctgac
    71341 attggtagcg gcccgtcggg cccgccagct tgaaaatggc aatacgccgc ttgtggacga
    71401 tgtccgcaat aacaaaccga ccgttaccgc cttaagggaa atcgccgccg ggcatatcgg
    71461 tacggaactg ttgacgcgca ataaataaat tctgccggaa acgcacgtcg gcacattctg
    71521 ccgccgtgca gtccgacggt ttgaaacgaa aaataaaata tgttccgaaa gccgtctgaa
    71581 atgcctgtcc ctcaacccac cgcaccttac gaccccctga ccgccgaagc gcgtgccctg
    71641 cttttccata ccgcctccta cctcaagccc gaggaacagg cggagcttga aaaagctgtc
    71701 gcctatgcgt ttcgcgccca cgacgggcaa acccgcaaaa gcggggagcc ctacatcacg
    71761 catccgattg ccgttgcgac gcagctcgcc ctttggcata tggacataca gggtctttgt
    71821 gcaggcgtga tgcacgacgt attggaagat acgggcgtga caaaagggga aatggcggcg
    71881 gtgttcggca atacggttgc cgagatggtg gacgggctgt ccaaactcga aaaactcaaa
    71941 tttgaagatc atgcagagca tcaggcggag agtttccgca aactgatttt ggcaatgacc
    72001 aaagatgtac gcgtcatcgt cgtcaaactt gccgaccgtc tgcataatat gcggacactc
    72061 ggttcgatgc gcccggacaa acgccgccgg attgcaaggg aaacccttga aatctatgca
    72121 cagattgcca accgcatagg tttgaataac gcatatcaag agcttcagga tttatcgttc
    72181 caaaacctgc atcccaaccg ctacgagact ttaaaaaaag cgatggacaa gagccggaag
    72241 aaccggcagg acgttgtcgg caaagtcttg cgcgcattcg gccagcggct ggtaggcgcg
    72301 aatatagagg ccaaaatcaa aggcagggaa aaaaacctgt acggcatcca tcagaaaatg
    72361 atggcgaaaa agctgcgctt tgccgaggtt atggatattt acggtttccg cgtcattgtc
    72421 aacagcattc cagcctgtta tgccgcactc ggcgcattgc acaccctcta tcagcccaag
    72481 cccgggcggt tcaaagacta tatcgccatt ccgaaaagca acgggtatca aagtctgcat
    72541 acgactttgg tcggtcctta cggcttgccg attgaagttc agatacgtac caaggaaatg
    72601 gatgctgttg ccgaaggtgg aatcgccgga cattggagct ataaatcata ttctaagacg
    72661 gtcgatcagg cggtgcttca cacaaaccgg tggctgaaaa atatcttaga tttgcaggca
    72721 agcagtgcca atgccattga gtttctcgaa cacgtcaaag tcgatttgtt tccgaacgaa
    72781 atctacatcc ttacgccaaa aggaaaaatc ctaactttgc ccaaaggggc aacgcctgtc
    72841 gattttgctt atgcggtgca taccgatatc gggcacaaaa ccgttgccgc acgtatcaac
    72901 aatatcatga tgccgttgcg tacgaagctc aaaaccggtg attccgtcga aattattaca
    72961 tccgaacacg ccaaacccaa tcccgcgtgg ttgaatttcg ccgtgtcagg cagggcgcgc
    73021 agtgccatac gccaatatat taaaaacctt aaccggcacg atgcggtcgt tttgggagag
    73081 aacctcttac aaaaagccct gtccagtttg ctgcccaaag atgtcctgct ttcagacggc
    73141 atcaaagaaa aataccttgc cgatctcaac gataaacaga cttcatttga ggaagtgctg
    73201 tacaacgtcg gtatggggca taccctgcct gtttatgtcg ctatgcatat tgccgaattg
    73261 gcaggaaagc atttcggtag tgaggtcagg ctcagttcca ttaaagtcga tgggcaggaa
    73321 agcgggcata ttcattttgc agagtgctgc caccctgttc ccggcgattc catccgtttg
    73381 ctgttggtta agggaaaagg catgattatc cacagagata cctgcccgac gttgttgaag
    73441 tccgatcccg aacagcagct ggatgcagac tgggaaaata tgaacgggca gaactaccgt
    73501 gtcgggcttc aagtccaatc ggaagacagc cacggcctgt tggcattaat ggcgcaagcg
    73561 atttccgatt ccggtgcgga cattgagtcg gtcgaaacac cgtctaaatc ccagtcggga
    73621 acggaaggtt ttgtcgaatt caaattctta ttgaaagtca agaatctgaa tcaattgaat
    73681 cagattattc aaaatctgca tagtattcca tatatccgca aagtcatcag aagttgaagc
    73741 aggtaaaacg ggttgccttt tgattaacag gcaacccgct ttatggttta tccgttcaat
    73801 tgcttatttg ttcaaatatc cggcaagcct ttcaacaatc tgcatcgccg cttcatcttt
    73861 acttgtttcg ggaaaagata gttccccgtc gtccccgata atggtaatcc ggttggtcgg
    73921 tttgcccatc gcgattgaaa catcattggc aactatcacc ggtatttttt tcttaatacg
    73981 tttttctcgt gcatatgcca ttacattctc cgtttcagcg gcaaaaccga tgcagaacgg
    74041 cgggttcggc aatgaggcaa tagaagccaa aatatcgggg ttctcatcca attcgatgga
    74101 taacggtttg gcatttttat cttttttgaa tttttgcgta ctcttgtttt taaccttata
    74161 gtctgagacg gcggcaacag aaataaaagc atcttgtttt tcaatcaaac gatgcactgc
    74221 gcgatgcata tcttcagcgc tgacggcttg aaccgtatcg gatatgccga aaggcagcgc
    74281 ggtttgaagc tgtccgtgaa tcaggctgac ttccgcaccg gcggcacggc acgcccgcgc
    74341 caaagctacc cccatttttc cgctggaggt atttgtgatg cccctgacag ggtcaatggt
    74401 ttcaaatgtc gcacctgcgg taatcaagat tttcttgccc cttaaaattt tcggtgtcca
    74461 caagtccgga agcaaatcca gcaattcggc aggttccggc atccttccca tgccattttc
    74521 tccgcaagcc tgttcgccca agcccggcat atagacagta atgccgtctg aaaccagttg
    74581 tgcgatattc cgttggttgg cagggttgag ccacatttcc acattcatcg cgggagcgat
    74641 ggcaagcgga catttccgtg cggctgccag actggtcagt aggttatctg ccacgccgtt
    74701 acagattttt gccacggtat tcatacttgc cggcgcaatc agaaaaacat ccgcattccg
    74761 ggtcaggttg atatgttcca taccgtttga accgttgccg ccgtgcgtgt cggtcaggac
    74821 aggattgccg cttaaagcct gaaaagtcag cggagaaaca aattcagttg ccgagcggct
    74881 cataaccacc gtaaccgaat gcccctgttt tttcagcaga cgaaccaact cgcaagactt
    74941 atacgccgca atactgcccg ttacacctaa aagaatatgt ttgcccattt tgacaatttc
    75001 taattacgaa gaaaaaacag cagccattct ataacaaagt gtggatacat tagataccgt
    75061 ttggatacaa
//
LOCUS       DAXISH010000003        74063 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.003, whole genome shotgun sequence.
ACCESSION   DAXISH010000003 DAXISH010000000
VERSION     DAXISH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 74063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74063
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.003"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(430..960)
                     /locus_tag="ACFOV4_000149"
                     /pseudo
     CDS             complement(430..960)
                     /locus_tag="ACFOV4_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611093.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(1968..2738)
                     /gene="xth"
                     /locus_tag="ACFOV4_000150"
     CDS             complement(1968..2738)
                     /gene="xth"
                     /locus_tag="ACFOV4_000150"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008311 - double-stranded DNA 3'-5' DNA
                     exonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFC7618246.1"
                     /translation="MKITTWNVNSLNVRLPQVQNLLADNPPDILVLQELKLDQDKFPA
                     AALQMMGWHCVWSGQKTYNGVAIVSRSVPQDVHFGLPALPDDPQRRVIAATVSGVRVI
                     NVYCVNGEALDSPKFKYKEQWFAALTEFVRDEMTRHGKLVLLGDFNIAPADADCYDPE
                     KWHEKIHCSSVERQWFQNLLDLGLTDSLRQVHPEGAFYTWFDYRGAMFQRKLGLRIDH
                     ILVSPAMAAALKDVRVDLETRALERPSDHAPVTAEFDW"
     gene            complement(2798..3079)
                     /locus_tag="ACFOV4_000151"
     CDS             complement(2798..3079)
                     /locus_tag="ACFOV4_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFC7618247.1"
                     /translation="MNTIPLHTILKLMAHPERMAILIQLLDSERNIAELAKSLSLPAT
                     AVSNHLNRLRVEGLVDFTRYHRIIEYRLVSEEAAAILHTVRDLENKRVA"
     gene            complement(3485..4366)
                     /gene="nadC"
                     /locus_tag="ACFOV4_000152"
     CDS             complement(3485..4366)
                     /gene="nadC"
                     /locus_tag="ACFOV4_000152"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HFC7618248.1"
                     /translation="MPSENTLFSLPDTLLRPIVEQALSEDLGRRGDITSAAVIAPDKT
                     AKLFLVSREDGVIAGMDLARLAFQTMDPSVRFQAEIRDGQAVRAGQTLAAVEGNARAL
                     LAAERTALNYLTHLSGIATATARAVAEVAEYGTDIVCSRKTIPLLRVLQKYAVRAGGG
                     VNHRMGLDDAVLIKDNHLAYCGSIAQAVQQAKQAVGALTCVEIEVDTLAQLDEAIAAG
                     AERILLDNMDDETLKEAANRCHTQTAHPHTIYCEASGGIGFDRLKRVAQTGVDGIALG
                     YLTHSSRSLDIGLDFVA"
     gene            complement(4442..5380)
                     /locus_tag="ACFOV4_000153"
     CDS             complement(4442..5380)
                     /locus_tag="ACFOV4_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618249.1"
                     /translation="MDAYPEAEAPPQSIVELVPVLIAVTDGGLRVLTVAQGTLLPNGP
                     LSPLRNSLQAGVKLWVAKQTSQPMGYVEQLYTFVDTHRRNEHGMPVLYVSYLGLVREA
                     ADSILHPDAKWQDCYGYFPWEDLRTDGGQRDAVVSRLRIWANSADTEEVRQMRLKRIH
                     LCWGVEPENWSEEYVLQRYEMLYESGLIVEAAEPQANFDFALTGQPMRHDHRRVLATA
                     LSRLRAKIKYRPVIFELMPPEFTLLQLQNSVEAISGRLLHKQNFRRQIQQQNLIEPSD
                     TGVSGSKGRPAQLCRFRDDVLPDRLISDIGLPLGSR"
     gene            5687..6799
                     /gene="nadA"
                     /locus_tag="ACFOV4_000154"
     CDS             5687..6799
                     /gene="nadA"
                     /locus_tag="ACFOV4_000154"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HFC7618250.1"
                     /translation="MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETAGRL
                     KDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEASTLVVAG
                     VRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAA
                     VKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVH
                     NEFKGQELAALKAEHPEAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSHPEKKFIVA
                     TDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGHNEI
                     LLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA"
     gene            7005..8513
                     /gene="nadB"
                     /locus_tag="ACFOV4_000155"
     CDS             7005..8513
                     /gene="nadB"
                     /locus_tag="ACFOV4_000155"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HFC7618251.1"
                     /translation="MQTDCDVLIAGNGLAALTLALSLPESFRIVILCKNRLDDTASRH
                     AQGGIAAAWSGEDDIEKHVADTLEAGAGLCDEAAVRTILSQGKLAIEWLLAQGVAFDQ
                     NNNGLHLTREGGHTCRRIAHVADYTGEAVMQSLTVQIRCRPNIRVCEQQMALDIQTES
                     GAACGLTVLDCRTQATYSIRARHTVLAGGGLGQIYAATTTPPECTGDAIAMAIRAGCA
                     VENLEFIQFHPTGLARSSENGRTFLISEAVRGEGGILTNQAGERFMPYYDRRAELAPR
                     DIVARAIAAEIAKQTQDFVSLDISHQPAAFVRRHFPSIHRHCLSQCGLDITRQAIPVR
                     PVQHYTCGGIQTDPCGRTSLPQLYSLGETACTGLHGANRLASNSLLECVVTARLAAQT
                     IADGQAFQAKTSPRPSESLSSEAGIFSDGIQSAFSRPVLQAFNQRHLGILRNDTGLRC
                     AIAQLRLWKQNQTEPHTASEYENRNLLECSLAVAQAAYRRRQNIGAHFNSDC"
     gene            complement(8691..9356)
                     /gene="pgmB"
                     /locus_tag="ACFOV4_000156"
     CDS             complement(8691..9356)
                     /gene="pgmB"
                     /locus_tag="ACFOV4_000156"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFC7618252.1"
                     /translation="MTFTAVLFDLDGVITDTAEYHYRAWKKLAEELGIGIDRKFNEQL
                     KGVSRDDSLKRILAHGGKTVGEAEFAELTRRKNDNYLEMIQAVKPEDVYLGILPLLEA
                     LKANGKKIALASASKNGPFLLERMGLTHFFDTVADPAAVAHSKPSPDIFLAAAEGVGA
                     DIRRCIGIEDAAAGVAAIKAAGALPIGVGKAEDLGSDIALVSDTAELTYAYLQNVWAQ
                     SGR"
     gene            complement(9369..11627)
                     /locus_tag="ACFOV4_000157"
     CDS             complement(9369..11627)
                     /locus_tag="ACFOV4_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFC7618253.1"
                     /translation="MYTRIMEISPWTLRSAKLEKEHKRLQESLTSLGNGYMGMRGSFE
                     ETYSADSHLGTYIAGVWFPDKTRVGWWKNGYPKYFGKAINALNFSKVKIFVDGQEVDL
                     AKNDVAGFSVELDMQHGVLRRSFTVFGVRFNVCKFLSVAQKELAVIRWEAVSVDGKTH
                     QVRIDSIIDADVKNEDSNYEEKFWQVLDKGVSDSLSYIAAQTVANPFGVEQFIVNAEQ
                     TFAGSFKALSGSQTDWQVSNSFEVEVGGTPKTFEKRVIVTTSRDYQGLEAVKAAGRAL
                     SEKVAGVVFETLLDAHKAGWLHRWEIADVVIEGNDEAQQGIRFNLFQLFSTYYGEDAR
                     LNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAEPEVTRNLLQYRRNQLPQAQHNARE
                     QGLAGALYPMVTFTGIECHNEWEITFEEIHRNGAIPYAIYNYTNYTGDEGYLAKEGLE
                     VLVEVSRFWADRVHFSKRSGKYMIHGVTGPNEYENNINNNWYTNTLAAWVLDYTREAL
                     AKYPRPDLNVSAAELEKWADISANMYRPYDEELGVFVQHDGFLDKGIRPVSALSPDDL
                     PLNQKWSWDKILRSPFIKQADVLQGIYFFGDRFNIDEKRRNFDFYEPMTVHESSLSPC
                     IHSILAAELGKEEKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLAIVQGFAQMK
                     TWGGKLSFAPFLPGAWTGYAFHINYRGRLIKVAVGKENVVFTLLKGEPLDLQVYGKDI
                     TLDGSHAAALEK"
     gene            complement(11861..12871)
                     /locus_tag="ACFOV4_000158"
     CDS             complement(11861..12871)
                     /locus_tag="ACFOV4_000158"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFC7618254.1"
                     /translation="MSDTPATRDFGLIDGRAVTGYVLSNRRGTRVCVLDLGGIVQEFS
                     VLADGVRENLVVSFDDAASYADNPFQINKQIGRVAGRIRGAAFDINGRTYRVEANEGR
                     NALHGGSHGLAVTRFNAVAADGRSVVLRSRLQQSADGYPNDLDLDISYRLDEDDRLTV
                     TYRATALGDTVFDPTLHIYWRLDAGLHDAVLHIPQGGHIPADAEKLPVSTVSDDLEVF
                     DFSRPKPLDAAVAALRRETGRAGFDDAYRVPSDIGRPAAVLQAGRRRRISIYSDRNGL
                     VIFTAAPQDFARHDAGVYDALATEAQTLPDSLNWPEFGNIRLNKGDTREATIAYGIES
                     LS"
     gene            complement(12875..14230)
                     /locus_tag="ACFOV4_000159"
     CDS             complement(12875..14230)
                     /locus_tag="ACFOV4_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC45 family MFS transporter"
                     /protein_id="HFC7618255.1"
                     /translation="MSEYTPQTAKQGLPALAKSTIWMLSFGFLGVQTAFTLQSSQMSR
                     IFQTLGADPHNLGWFFILPPLAGMLVQPIVGHYSDRTWKPRLGGRRLPYLLYGTLIAV
                     IVMILMPNSGSFGFGYASLAALSFGALMIALLDVSSNMAMQPFKMMVGDMVNEEQKGY
                     AYGIQSFLANTGAVVAAILPFVFAYIGLANTAEKGVVPQTVVVAFYVGAALLVITSAF
                     TIFKVKEYDPETYARYHGIDVAANQEKANWFELLKTAPKAFWTVTLVQFFCWFAFQYM
                     WTYSAGAIAENVWHTTDASSVGYQEAGNWYGVLAAVQSVAAVICSFVLAKVPNKYHKA
                     GYFGCLALGALGFFSVFFIGNQYALVLSYTLIGIAWAGIITYPLTIVTNALSGKHMGT
                     YLGLFNGSICMPQIVASLLSFVLFPMLGGLQATMFLVGGVVLLLGAFSVFLIKETHGG
                     V"
     gene            14617..16293
                     /gene="ettA"
                     /locus_tag="ACFOV4_000160"
     CDS             14617..16293
                     /gene="ettA"
                     /locus_tag="ACFOV4_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0045900 - negative regulation of
                     translational elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HFC7618256.1"
                     /translation="MSQQYVYSMLRVSKVVPPQKTIIKDISLSFFPGAKIGLLGLNGA
                     GKSTVLRIMAGVDKEFEGEAVPMGGIKIGYLPQEPELDPEKTVREEVESGLGEVAAAQ
                     KRLEEVYAEYANPDADFDALAEEQGRLEAIIAAGSSTGGGAEHELEIAADALRLPEWD
                     AKIDNLSGGEKRRVALCKLLLSKPDMLLLDEPTNHLDAESVEWLEQFLVRFPGTVVAV
                     THDRYFLDNAAEWILELDRGHGIPWKGNYSSWLEQKEKRLENEAKSEAARVKAMKQEL
                     EWVRQNAKGRQAKSKARLARFEEMSNYEYQKRNETQEIFIPVAERLGNEVIEFVNVSK
                     SFGDKVLIDDLSFKVPAGAIVGIIGPNGAGKSTLFKMIAGKEQPDSGEVKIGQTVKMS
                     LIDQSREGLQNDKTVFDNIAEGRDILQVGQFEIPARQYLGRFNFKGSDQSKITGQLSG
                     GERGRLHLAKTLLSGGNVLLLDEPSNDLDVETLRALEDALLEFAGSVMVISHDRWFLD
                     RIATHILACEGDSKWVFFDGNYQEYEADKKRRLGEEGAKPKRIKYKPVTR"
     gene            complement(16353..16838)
                     /locus_tag="ACFOV4_000161"
     CDS             complement(16353..16838)
                     /locus_tag="ACFOV4_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFC7618257.1"
                     /translation="MADFKPDFAWLLKRPLCFLAFGFGSGLAPFAPGTFGTLAALPLA
                     FVLILLGIDGLLLAFLCIVLFMWGIRICAYAERETGVSDHGGIVWDEIVAMLFVLAFV
                     PFRWTWWLAAFVLFRLFDALKPSPVGWFDKNLHGGLGIMADDMAAAVMTLIVLRIAML
                     F"
     gene            complement(16831..17787)
                     /gene="thiL"
                     /locus_tag="ACFOV4_000162"
     CDS             complement(16831..17787)
                     /gene="thiL"
                     /locus_tag="ACFOV4_000162"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HFC7618258.1"
                     /translation="MKEFDFIKRYLQTGTDNDVVLGIGDDAAIVRPREGFDLCFSADM
                     LLKDRHFFANVKPEDLAWKVLAVNVSDMAAMGAIPRWVLLSAALPELDEVWLKRFCGS
                     FFGLAKKFGVTLIGGDTTKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMA
                     AAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLALLPFARAAQDVSDGLAQDLGH
                     ILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLD
                     AAERCGVPVTRIGKINGGCRLKVLDDGGRELELHSLGFDHFG"
     gene            complement(18632..19360)
                     /gene="rmpM"
                     /locus_tag="ACFOV4_000163"
     CDS             complement(18632..19360)
                     /gene="rmpM"
                     /locus_tag="ACFOV4_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding outer membrane protein
                     RmpM"
                     /protein_id="HFC7618259.1"
                     /translation="MTKQLKLSALFVALLASGTAVAGEASVQGYTVSGQSNEIVRNNY
                     GECWKNAYFDKASQGRVECGDAVAAPEPEPEPEPAPAPVVVVEQAPQYVDETISLSAK
                     TLFGFDKDSLRAEAQDNLKVLAQRLGQTNIQSVRVEGHTDFMGSDKYNQALSERRAYV
                     VANNLVSNGVPVSRISAVGLGESQAQMTQVCEAEVAKLGAKVSKAKKREALIACIEPD
                     RRVDVKIRSIVTRQVVPAHNHHQH"
     gene            19724..20674
                     /locus_tag="ACFOV4_000164"
     CDS             19724..20674
                     /locus_tag="ACFOV4_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CysB family HTH-type transcriptional regulator"
                     /protein_id="HFC7618260.1"
                     /translation="MKLQQLKYALEVYQHNLNVSEAAEALFTSQPGISKQIKLLEEEI
                     GIQIFIRSGKRVVSVSQPGKVVLDIAERILRDVQNIKNIGSEFTGQDSGSLTVATTHT
                     QARYALPLIVADFVKRYPKVNLTIKQGSPAAIARMVTSGEADLAIVTERIDDHPELGK
                     LPCYDWTHAVIVPNNHPLLECRNPLRIEDLARFPLITYEFAFNAGSSIARAFSKARLE
                     QPDVALAAADTDVLKTYVRLGLGVGLMAKMAYNPDTDGDLQLVDAAHLFEPSPTWIAL
                     RSDTYLRGYAYDFIQAFAPHLTREKVDRILYTPISEDFSI"
     gene            complement(20787..21521)
                     /gene="fnr"
                     /locus_tag="ACFOV4_000165"
     CDS             complement(20787..21521)
                     /gene="fnr"
                     /locus_tag="ACFOV4_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HFC7618261.1"
                     /translation="MASHNTTHQMKTLCSSCSLRELCLPVGLLPNELSQLDAVIRQSR
                     RLKKGEYLFCVGEAFTSLFAIRSGFFKTTVASQDGRDQVTGFFMSGELIGMDGICSHV
                     HSCDAVALEDSEVCELPFTHIEELGQNIPSLRTHFFRMMSREIVRDQGVMLLLGNMRA
                     EERIAAFLLNLSQRLYSRGFAANDFILRMSREEIGSYLGLKLETVSRTLSKFHQEGLI
                     SVEHKHIKILNLQVLKKMVSGCSHAI"
     gene            21724..23145
                     /gene="hemN"
                     /locus_tag="ACFOV4_000166"
     CDS             21724..23145
                     /gene="hemN"
                     /locus_tag="ACFOV4_000166"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003684340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004109 - coproporphyrinogen oxidase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HFC7618262.1"
                     /translation="MKIIQIQNNHNVNDDRPEFDRALIASLPASGPRYTSYPTADRFH
                     DGFREGEYIKALHLRGMGALNKPLSLYIHIPFCNTICYYCGCNKIITKDKSRADAYIE
                     YLEKEMELLAPHLNGRHQLAQLHFGGGTPTFLSDEQIERVFRMIRKHFELIPTGEYSI
                     EIDPRKVSRDTVLMLGRLGFNRMSIGIQDFDPKVQAAVNRIQSYEETKEVIDAAREAG
                     FKSVSVDLIYGLPHQTSESIKTTIDTVLSLDPDRLALYHYAHLPHVFKPQRRIDTASV
                     PDSEEKLDMLQYCVQTLTERGYVFIGMDHFAKPDDELSIALKEGFLQRNFQGYSTYAD
                     CDLVAIGVSSIGKIGSTYSQNERDIDAYYAAIDEGRLPIMRGYQLNQDDILRRNIIQD
                     LMCRFALDYRIYESMFGIPFDRYFKDELADLEKLAGLGLVRLNSHGLTVTPKGRFLIR
                     NIAMVFDYHLRHKETKAKYSQTV"
     gene            complement(23498..25072)
                     /locus_tag="ACFOV4_000167"
     CDS             complement(23498..25072)
                     /locus_tag="ACFOV4_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003748724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HFC7618263.1"
                     /translation="MAQIQMSANVKTINAVFAAMLVGTVGYFIYWGLGYTHYNYAALF
                     IIATMFGVFMAFNIGGNDVANSFGTSVGAGTLTIPQALLIAAVFEVSGAVIAGGEVTN
                     TIRKGIVDLKGVDFEPIQFVFIMMSALLAAALWLLFASKKGLPVSTTHSIIGGIVGSA
                     VCMAVMNDAASGDLIRWGKLGGIGVSWVLSPVLGGAVSYFLFSRVKKNVLDYNAWAEG
                     TLKGIKQEKKAYKERHRLFFEGLSEAEKVEYATKMAHDAQIYDEPEFDPQELQSEYYR
                     GLYAFDNRKNNVDSYKALHSWIPFIASFGAMMISAMLIFKGLKNLHLGMSNVNSFLTI
                     FMIGAAVWMGTFVFAKSLKRKDLGKSTFQMFSWMQVFTACGFAFSHGANDIANAIGPF
                     AAIMDVLRTNSVAAQNVVPPIAMLTFGIALIVGLWFVGKEVIKTVGTSLAEMHPASGF
                     TAELSAASVVMGASLMGLPVSSTHILVGAVLGIGLVNRNANWKLMKPIGLAWVITLPA
                     AAVLSVVCYLVLQAVF"
     gene            25397..26497
                     /locus_tag="ACFOV4_000168"
     CDS             25397..26497
                     /locus_tag="ACFOV4_000168"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HFC7618264.1"
                     /translation="METQLYIGIMSGTSMDGADAVLIRMDGGKWLGAEGHAFTPYPDR
                     LRRQLLDLQDTGADELHRSRILSQELSRLYAQTAAELLCSQNLAPSDITALGCHGQTV
                     RHAPEHGYSIQLADLPLLAERTQIFTVGDFRSRDLAAGGQGAPLVPAFHKALFRDDKE
                     TRVVLNIGGIANISVLPSDAPAFGFDTGPGNMLMDAWMQAHWQLPYDKNGAKAAQGNI
                     LPQLLDRLLAHPYFAQPHPKSTGRELFALNWLETYLGGGENRYDVLRTLSRFTAQTVF
                     DAVSHAAADARQMYICGGGIRNPVLMADLAEYFGTRVSLHSTAELKLDPQWVEAAAFA
                     WLAACWINRIPGSPHKATGASKPCILGAGYYY"
     gene            26616..27557
                     /gene="mafA"
                     /locus_tag="ACFOV4_000169"
     CDS             26616..27557
                     /gene="mafA"
                     /locus_tag="ACFOV4_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin MafA"
                     /protein_id="HFC7618265.1"
                     /translation="MKILLLLIPLVLTACGTLTGIPAHGGGKRFAVEQELVAASSRAA
                     VKEMDLSALKGRKAALYVSVMGDQGSGNISGGRYSIDALIRGGYHNNPESATRYSYPA
                     YDTTATTKSDALSSVTTSTSLLNAPAAALTRNSGRKGERSAGLSVNGMGDYRNETLLA
                     NPRDVSFLTNLIQTVFYLRGIEVVPPEYADTDVFVTVDVFGTVRSRTELHLYNAETLK
                     AQTKLEYFAVDRDSRKLLIAPKTAAYESQYQEQYALWMGPYSVGKTVKASDRLMVDFS
                     DITPYGDTTAQNRPDFKQNNGKNPDVGNEVIRRRKGG"
     gene            27561..28829
                     /gene="mafB"
                     /locus_tag="ACFOV4_000170"
     CDS             27561..28829
                     /gene="mafB"
                     /locus_tag="ACFOV4_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 1"
                     /protein_id="HFC7618266.1"
                     /translation="MKPLRRLTNLLAACAVAAAALIQPALAADLAQDPFITDNAQRQH
                     YEPGGKYHLFGDPRGSVSDRTGQINVIQDYTHQMGNLLIQQANINGTIGYHTRFSGHG
                     HEEHAPFDNHAADSASKEQGNVDDGFTVYRLNWEGHEHHPADAYDGPKGSDYPDPTGA
                     RDEYTYHVNGTARSIKLNPTDTRSIRQRISDNYNNLGSNFSDRADEANRKMFEHNAKL
                     DRWGNSMEFINGVAAGALNPFISAGEAVDQWMQENPNAAETVEALVNVLPFAKVKNLT
                     KAAKPGKAAVSGDFSDSYKHNTASRLSQSVDGEMFQTRNVDFKAKSIGTKIHDGAQGK
                     HISGHRNYIEGKSTLNQNINPQELLNGIHSGAYPVISKGARGNPVVDFGYPIGSDGKS
                     GLSTNFGTIHSGKNGVHIVPANPKTIKKVQ"
     gene            28832..29149
                     /locus_tag="ACFOV4_000171"
     CDS             28832..29149
                     /locus_tag="ACFOV4_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618267.1"
                     /translation="MNILPSWLRVGMNIAMLGMIHSDIRLITVDYEEGRRFLKIKNYL
                     SREAITEDHEDMEYLITELWSMCGEYFDEADFECIYSNHSSMELNQINGAVFRRKELI
                     SQA"
     gene            29283..29912
                     /locus_tag="ACFOV4_000172"
     CDS             29283..29912
                     /locus_tag="ACFOV4_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HINT domain-containing protein"
                     /protein_id="HFC7618268.1"
                     /translation="MVKTADGYKAIARIRTGDRVFSKDEASGKTGYKPVTARYGNPYQ
                     ETVYIKVSDGIGNSQTLISNRIHPFYSGGKWIKAEDLKAGSRLLSESGKTQTVRNIVV
                     KPTPLKAYNLTVADWHTYFVKGSQAETEGVWVHNSCPPKRTGSSKNEKHGDGGRSQIS
                     AESRIAELKNKIIPGMPKNERLKIEKTIKNITKNANRKAKGEEHGRRGR"
     gene            29893..30348
                     /locus_tag="ACFOV4_000173"
     CDS             29893..30348
                     /locus_tag="ACFOV4_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618269.1"
                     /translation="MVDAVVKTPEFLPFTSVGIFRFGADITQYKNILGTFMYEPPDEF
                     RTEYYESPDSNLLIAVKKNKIISIFCYQELYFMGVNIIGLNFEDFKQLFHHPKSYGVD
                     KYYLSNESYPTYVYEFDEIGVQAWEAKGKIVTIIAGGKDNYSTEPYYDE"
     gene            30569..30928
                     /locus_tag="ACFOV4_000174"
     CDS             30569..30928
                     /locus_tag="ACFOV4_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618270.1"
                     /translation="MASYVSIKGWIECSDDDIKIIQENINNFWNNCPFNIEEKESAKI
                     YKSGWVFPTNSFNWSSYIFFGACVKSYFIIYFEKCIKTIMELDIEISGFFELDYYEDS
                     YKVHWKINNGNLIQTTN"
     gene            31143..31913
                     /locus_tag="ACFOV4_000175"
     CDS             31143..31913
                     /locus_tag="ACFOV4_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HINT domain-containing protein"
                     /protein_id="HFC7618271.1"
                     /translation="MVKTADGYKAIARIRVGDRVFAKDEASGKTGYKPVTTRYGNPYQ
                     ETVYIEISDGIGNNQTLISNSIHPFYSQGKWIQAGRLKKGDTLLSESGAKQTVQNITL
                     KQQPLKAYNLTVADWHTYFVKGDRAETEGVWVHNDCPYGSSSAKGKSGSERNTAKRGT
                     FRQETLKNAWDLAADGSQPNSKKCPTCGKDVYGNPHNKEKRNTKDGWDGSHNPSWSNR
                     QHSSDRKEQLNDYNKGVSLECRHCNRSGGNKDERFKKK"
     gene            31910..32455
                     /locus_tag="ACFOV4_000176"
     CDS             31910..32455
                     /locus_tag="ACFOV4_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004463655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="suppressor of fused domain protein"
                     /protein_id="HFC7618272.1"
                     /translation="MITVEHLEHYLGEIESGIKCLDRRYHLSVSVFPSQPYKGVTTFS
                     TLGLNRYDLNYKSRFELIFTCSEEWNKENIAAFLSGVAEYLIDNRQPILRGEIIQLPR
                     VIIEGSKMDALYVSAPFYFDDDFQVCYGGHYNTVFPLLVPLYKQEAELVEKKGWNAFE
                     QFLLDSEVGNLSDMNRKPFVW"
     gene            32620..33294
                     /locus_tag="ACFOV4_000177"
     CDS             32620..33294
                     /locus_tag="ACFOV4_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin-type HINT domain-containing
                     protein"
                     /protein_id="HFC7618273.1"
                     /translation="MAHIQAGDRVLSKDEASGETGYKPVTTRYGNPYRETVYIKVSDG
                     IGNSQTLISNRIHPFYSQGKWIQAGRLKKGDTLLSESGAKQTVQNITFKQQPLKAYNL
                     TVADWHTYFVKGDKAETEGVWVHNDCPYGNLSDNKSVGEGKKFTPAQKKAIIQENMNR
                     NGGVVKSDQSGEVLVRPKKSQKGITPPSNEWQIDHVQAKSKGGSNSYKNAQVLSRREN
                     IKKSNK"
     gene            33303..33574
                     /locus_tag="ACFOV4_000178"
                     /pseudo
     CDS             33303..33574
                     /locus_tag="ACFOV4_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011798993.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            33740..33970
                     /locus_tag="ACFOV4_000179"
     CDS             33740..33970
                     /locus_tag="ACFOV4_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MafI family immunity protein"
                     /protein_id="HFC7618274.1"
                     /translation="METLDERIKNLGKSLEDRIDANLIDATLEYITFSERLLAFETLC
                     DYIEDFNIQLTEKESQEISFINKEFGIESTSD"
     gene            34390..34791
                     /locus_tag="ACFOV4_000180"
     CDS             34390..34791
                     /locus_tag="ACFOV4_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618275.1"
                     /translation="MKIKPLQFSNNNHRFYVDKICVTEQDVNILASDRNYELNIEIFI
                     DNIIHFQITDESYKVKFSEYLFENKEKNDWDRNPAINYFFEIIDDSYMDWLKEESFDF
                     FEKKYYKAYIFFFSDSVIEVISSTEPVFYSK"
     gene            34958..35452
                     /locus_tag="ACFOV4_000181"
     CDS             34958..35452
                     /locus_tag="ACFOV4_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618276.1"
                     /translation="MENRFAKIVKDIFSFTQFVSEAENKIPNQSSRYYDCWWELEILN
                     ASALEDWEISGKPEKWEKWTEKYQTEALQSVKHLFAEEVPENNIVCDISHFLHFADWA
                     EADIPNQSRLYAEYWWEMEMFKMSVLEDWEHSGKPLDWKKWQRQYRSEAFELVKKLNR
                     SKQE"
     gene            35572..36705
                     /locus_tag="ACFOV4_000182"
     CDS             35572..36705
                     /locus_tag="ACFOV4_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618277.1"
                     /translation="MFKKFKPVLLSFFALVFAFWLGTGIAYEINPRWFLSDTATEIPE
                     NPNAFVAKLARLFRNADRAVVIVKESMRTEESLAGAVDDGPLQSEKDYLALAIRLSRL
                     KEKAKWFHVTEQEHGKEVWLDYHIGEGGLVAVSLSQRSPEAFVNAEYLYRNDRPFSVN
                     VYGGTAHGENYETTGEYRVVWQPDGSVFDASGRGKIGEDVYEHCLGCYQMAQVYLAKY
                     RDVANDEQKVWDFREESNRIASDSRDSVFYQNMRELMPRGMKANSLVVGYDADGLPQK
                     VYWSFDNGKKRQSFEYYLKNGNLFIAQSSTVALKADGVTADMQTYHAQQTWYLDGGRI
                     VREEKQGDRLPDFPLNLEDLDKEVRRYAEAAARRSGGRRDLSH"
     gene            complement(36792..37067)
                     /locus_tag="ACFOV4_000183"
     CDS             complement(36792..37067)
                     /locus_tag="ACFOV4_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618278.1"
                     /translation="MNEGEVVLTPEQIQTLRGYAFRGDTYGGWRYLANLGDRYADDAA
                     AIVGKDANLNGLNLWMKKGVENLWDDTVGKKARLMCISVFWIVVFNL"
     gene            complement(37084..37851)
                     /locus_tag="ACFOV4_000184"
     CDS             complement(37084..37851)
                     /locus_tag="ACFOV4_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RTX iron-regulated FrpC family protein"
                     /protein_id="HFC7618279.1"
                     /translation="MRPYATTIYQLFILFIGSVFTMTSCEPVNEQTSFNNPEPMTGFE
                     HTVTFDFQGTKMVIPYGYLARYTQDNATKWLSDTPGQDAYSINLIEISVYYKKTDQGW
                     VLEPYNQQNKAHFIQFLRDGLDSVDDIVIRKDACSLSTTMGERLLTYGVKKMPSAYPE
                     YEAYEDKRHIPENPYFHEFYYIKKGENPAIITHRNYHRYGENDYSTSVGSCINGFTVR
                     YYPFIREKQQLTQQELVGYHQQVEQLVQSFVNNPSKK"
     gene            complement(38237..38512)
                     /locus_tag="ACFOV4_000185"
     CDS             complement(38237..38512)
                     /locus_tag="ACFOV4_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFC7618280.1"
                     /translation="MNASNWSVYLILCENSAFYCGISPNPQQRLAAHTTGKGAKYTRV
                     FKPVAMRIVAGGMDKGTALKQEIAVKKLTAAQKRKLWEQAEKMPSET"
     gene            complement(38509..39792)
                     /locus_tag="ACFOV4_000186"
     CDS             complement(38509..39792)
                     /locus_tag="ACFOV4_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC7618281.1"
                     /translation="MTASKSGFIGQIFSRNMLVCIFTGFASGLPLYFLINLIPAWLRS
                     EQVDLKSIGLMALIGLPFTWKFLWSPLMDAVRLPVLGRRRGWMLLTQAGLLAALAAYA
                     FLNPRNHLPLIAGLSVLVAFFSASQDIVLDAFRREILSDEELGLGNSVHVNAYRVAAL
                     IPGSLSLVLADRMPWPEVFVITSLFMLPGLLMTLFLAREPVLPPAVPKTLKQTVVEPF
                     KEFFTRKGIASAVCVLLFIFLYKLGDSMATALATPFYLDMGFSKTDIGLIAKNAGLWP
                     AVAAGILGGVWMLKIGVNKALWLFGAVQAVTVLGFVWLAGFGPFDTVGTGERLMLAAV
                     IGAEAVGVGLGTAAFVSYMARETNPAFTATQLALFTSLSAVPRTVINSFAGYLIEWLG
                     YVPFFQLCFILALPGMLLLLKVAPWNGEKTQDAGR"
     gene            complement(39948..41366)
                     /gene="glnA"
                     /locus_tag="ACFOV4_000187"
     CDS             complement(39948..41366)
                     /gene="glnA"
                     /locus_tag="ACFOV4_000187"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFC7618282.1"
                     /translation="MSIKNAVKLIEESEARFVDLRFTDTKGKQHHFTVPARIVLEDPE
                     EWFENGQAFDGSSIGGWKGIQASDMQLRPDASTAFVDPFYDDATVVLTCDVIDPADGQ
                     GYDRDPRSIARRAEAYLKSSGIGETAYFGPEPEFFVFDGIEFETDMHKTRYEITSESG
                     AWASGLHMDGQNTGHRPTVKGGYAPVAPIDCGQDLRSAMVNILEELGIEVEVHHSEVG
                     TGSQMEIGTRFATLVKRADQTQDMKYVIQNVAHNFGKTATFMPKPIMGDNGSGMHVHQ
                     SIWKDGQNLFAGDGYAGLSDTALYYIGGIIKHAKALNAITNPSTNSYKRLVPHFEAPT
                     KLAYSAKNRSASIRIPSVNSSKARRIEARFPDPTANPYLAFAALLMAGLDGIQNKIHP
                     GDPADKNLYDLPPEEDALVPTVCASLEEALAALKADHEFLLRGGVFSKDWIDSYIAFK
                     EEDVRRIRMAPHPLEFEMYYSL"
     gene            41450..41599
                     /locus_tag="ACFOV4_000188"
     CDS             41450..41599
                     /locus_tag="ACFOV4_000188"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618283.1"
                     /translation="MPSETRPASNFKLENIVSDGKIVNNMLRFVCSKAEYPPFCPNAD
                     KTDAA"
     gene            41677..42486
                     /gene="aroE"
                     /locus_tag="ACFOV4_000189"
     CDS             41677..42486
                     /gene="aroE"
                     /locus_tag="ACFOV4_000189"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFC7618284.1"
                     /translation="MHALPRYAVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIG
                     GFAQAVSTFFETGGCGANVTVPFKQEAFHLADEHSERALAAGAVNTLIFLKNGKLRGD
                     NTDGIGLANDITQVKNIAIEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKA
                     EELARLFGIEAVPMADVNGGFDIIINGTSGGLSGQLPAVSREIFRNCRLAYDMVYGDA
                     AQAFLNFAQSNGAAEVSDGLGMLVGQAAASYHIWRGFTPDIRPIIEYMKAL"
     gene            42489..43190
                     /gene="mtgA"
                     /locus_tag="ACFOV4_000190"
     CDS             42489..43190
                     /gene="mtgA"
                     /locus_tag="ACFOV4_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009274 - peptidoglycan-based cell wall
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HFC7618285.1"
                     /translation="MFRIIKWLIALPVGIFIFFNAYVYGNIITYRAVAPHQTAFMSMR
                     MKQFEQEGRDVALDYRWMPYNRISVNLKKALIASEDARFAGHGGFDWGGIQNAIRRNR
                     NSGKVKAGGSTISQQLAKNLFLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSI
                     EWHYGVFGAEAASRYFYQIPAAKLTKQQAAKLTACVPAPLYYADHPKSKRLRNKTNIV
                     LRRMGSAELPESDTD"
     gene            complement(43515..43590)
                     /locus_tag="ACFOV4_000191"
     tRNA            complement(43515..43590)
                     /locus_tag="ACFOV4_000191"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43555..43557),aa:Phe,seq:gaa)
     gene            complement(43781..44515)
                     /gene="lptB"
                     /locus_tag="ACFOV4_000192"
     CDS             complement(43781..44515)
                     /gene="lptB"
                     /locus_tag="ACFOV4_000192"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HFC7618286.1"
                     /translation="MSANVSRLVVQNLQKSFKKRQVVKSFSLEIESGEVVGLLGPNGA
                     GKTTSFYMIVGLIAADAGSVTLDGQELRHLPIHERARLGVGYLPQEASIFRKMTVEQN
                     IRAILEIRTKDKNQIDREIEKLLADLNIGHLRRSPAPSLSGGERRRVEIARVLAMKPH
                     FILLDEPFAGVDPIAVIDIQKIIGFLKSRGIGVLITDHNVRETLSICDRAYIISDGAV
                     LASGKPDDLVGNEQVRSVYLGKNFKY"
     gene            complement(44589..45119)
                     /gene="lptA"
                     /locus_tag="ACFOV4_000193"
     CDS             complement(44589..45119)
                     /gene="lptA"
                     /locus_tag="ACFOV4_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0001530 - lipopolysaccharide binding
                     [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide transport periplasmic protein
                     LptA"
                     /protein_id="HFC7618287.1"
                     /translation="MIQKICKLFVLIAFFSASPAFALQSDSRQPIQIEADQGSLDQAN
                     QSTTFSGNVVIRQGTLNISAARVNVTRGGKGGESVRAEGSPVRFSQTLDGGKGTVRGQ
                     ANNVAYSSAGSTVVLTGNAKVQRGGDVAEGAVITYNTKTEVYTISGSTKSGAKSASKS
                     GRVSVVIQPSSTQKSE"
     gene            complement(45100..45681)
                     /gene="lptC"
                     /locus_tag="ACFOV4_000194"
     CDS             complement(45100..45681)
                     /gene="lptC"
                     /locus_tag="ACFOV4_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HFC7618288.1"
                     /translation="MKVRWRYGIAFPLILAVALGSLSAWLGRISEVEIEEVRLNPDEP
                     QYTMDGLDGRRFDEQGYLKEHLSSKGAKQFPESSDIHFDSPHLVFFQEGRLLYEVGSD
                     EAVYHTENKQVLFKNNVVLTKTADGKRQAGKVEAEKLHVDTESQYAQTDTPVSFQYGA
                     SHGQAGGMTYDHKTGMLNFSSKVKATIYDTKDM"
     gene            complement(45678..46214)
                     /locus_tag="ACFOV4_000195"
     CDS             complement(45678..46214)
                     /locus_tag="ACFOV4_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KdsC family phosphatase"
                     /protein_id="HFC7618289.1"
                     /translation="MQAISPELQARAAKIKLLILDVDGVLTDGRIFIRDNGEEIKSFH
                     TLDGHGLKMLQASGVQTAIITGRDAPSVGIRVKQLGINYYFKGISDKRAAYEELRAQV
                     GVEEAECAFVGDDVVDLPVMVRCGLPVAVPDAHWFTLQHAAYIAKRPGGAGAVREVCD
                     LIMQAQGTLGAALNEYIK"
     gene            complement(46432..47406)
                     /locus_tag="ACFOV4_000196"
     CDS             complement(46432..47406)
                     /locus_tag="ACFOV4_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HFC7618290.1"
                     /translation="MAGNEKYLDWAREVLHTEAEGLREIAADLDENFALAADALLHCK
                     GRVVITGMGKSGHIGRKMAATMASTGTPAFFVHPAEAAHGDLGMIVDNDVVVAISNSG
                     ESDEIAAIIPALKRKDITLVCITARPDSTMARHADIHITASVSKEACPLGLAPTTSTT
                     AVMALGDALAVVLLRARAFTPDDFALSHPAGSLGKRLLLRVADIMHKGGGLPAVRLGT
                     PLKEAIVSMSEKGLGMLAVTDGQGRLKGVFTDGDLRRLFQECDNFTGLSIDEVMHTHP
                     KTISAERLATEALKVMQANHVNGLLVTDADGVLIGALNMHDLLAARIV"
     gene            47503..48558
                     /gene="tal"
                     /locus_tag="ACFOV4_000197"
     CDS             47503..48558
                     /gene="tal"
                     /locus_tag="ACFOV4_000197"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004801 - transaldolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HFC7618291.1"
                     /translation="MTILSDVKALGQQIWLDNLSRSLVQSGELAQMLKQGVCGVTSNP
                     AIFQKAFAGDALYADEVAALKQQDLTPKQRYETMAVADVRAACGVCLAEHESTGGKTG
                     FVSLEVSPELSKDAQGTVEEARRLYAAIGCKNAMIKVPATDAGIDALETLVSDGISVN
                     LTLLFSRAQTLKAYAAYARGIAKRLAAGQSVAHIHVVASFFISRVDSALDTTLPDRLK
                     GKIAIALAKAAYQDWEQYFTAPEFAALEAQGANRVQLLWASTGVKNPAYPDTLYVDSL
                     IGAHTVNTVPDATLKAFIDHGTAKATLTEGADEAQAQLAEIAALGIDVETLAARLQED
                     GLKQFEEAFEKLLAPLV"
     gene            48572..48706
                     /locus_tag="ACFOV4_000198"
     CDS             48572..48706
                     /locus_tag="ACFOV4_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618292.1"
                     /translation="MPSERLSDGIARLTGHSAAYQGFTLKILMGKKLMHDITHQHKRK
                     "
     gene            48711..49001
                     /locus_tag="ACFOV4_000199"
     CDS             48711..49001
                     /locus_tag="ACFOV4_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618293.1"
                     /translation="MAKALEIISPNEIYSDLIFKDPVPPHTIYTELMKLVSRNASNER
                     IADRAFDFFSSGLMDGSATEEQYNALYDLTLLEEPGMELNKDEIMALINSLK"
     gene            49018..49905
                     /gene="gluQRS"
                     /locus_tag="ACFOV4_000200"
     CDS             49018..49905
                     /gene="gluQRS"
                     /locus_tag="ACFOV4_000200"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HFC7618294.1"
                     /translation="MYTGRFAPSPTGLLHIGSLLTAAASYADARSNGGKWLVRMEDLD
                     PPREMPGAANHILHTLEAFGFEWDGEVAYQSRRYALYEETLCRLQTAGLVYPCHCSRK
                     DWQTGARRGADGFVYNGRCRNPQQRPAPQGKQPAWRIRVPDRVIGFSDGIVGGYAQNL
                     AGDIGDFVLLRADGYWAYQLAVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLDVPT
                     PQYAHLPLLTNAQGQKWSKQTLAPALDLNRREQLLRQVFRYLNLPEAPEADRPAELLD
                     WAVAHWDMDKVPKHAITTP"
     gene            complement(49975..50985)
                     /gene="dusA"
                     /locus_tag="ACFOV4_000201"
     CDS             complement(49975..50985)
                     /gene="dusA"
                     /locus_tag="ACFOV4_000201"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0002943 - tRNA dihydrouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HFC7618295.1"
                     /translation="MNDNTHTLPPRRLSVAPMLDWTDRHYRYMARQITRNAWLYSEMV
                     NAGAIVYGDKDRFLMFNEGEQPVALQLGGSDPSDLAKAAKAAEAYGYNEVNLNCGCPS
                     PRVQKGSFGACLMNEVGLVADCLNAMQDAVGIPVTVKHRIGVDRQTEYQTVADFVGTL
                     RDKTACKTFIVHARNAWLDGLSPKENRDVPPLKYDYVYRLKQEFPGLEIIINGGITTN
                     EAIAGHLQHVDGVMVGREAYHNPMVMREWDRLFYGDTANPIGYADLVQRLYTYSQAQI
                     QAGRGTILRHIVRHSLGLMHGLKGARTWRRMLSDATLLKDNDGSLILEAWKEVERANT
                     RE"
     gene            complement(51016..51507)
                     /gene="dtd"
                     /locus_tag="ACFOV4_000202"
     CDS             complement(51016..51507)
                     /gene="dtd"
                     /locus_tag="ACFOV4_000202"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFC7618296.1"
                     /translation="MRAVIQKTVGAKVDVVSENGTETCGKIDGGFVVLLGVTHSDTEK
                     DAHYIADKIAHLRVFEDEAGKLNLSLKDVGGAVLLVSQFTLYADAASGRRPSFSQAAP
                     AEQAQQLYLRTAELLRGHGIHVETGRFRTHMQVSLCNDGPVTILLDSFMTRISPKMKV
                     VPD"
     gene            complement(51581..52339)
                     /locus_tag="ACFOV4_000203"
     CDS             complement(51581..52339)
                     /locus_tag="ACFOV4_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFC7618297.1"
                     /translation="MKQKKTAAAVIAAMLAGFAAAKAPEIDPALVDTLVAQIMQQADR
                     HAEQSQKPDGQAIRNDAVRRLQTLEVLKNRALKEGLDKDKDVQNRFKIAEASFYAEEY
                     VRFLERSETVSESALRQFYERQIRMIKLQQVSFATEEEARQAQQLLLKGLSFEGLMKR
                     YPNDEQAFDGFIMAQQLPEPLASQFAAMNRGDVTRDPVKLGERYYLFKLSEVGKNPDA
                     QPFELVRNQLEQGLRQEKARLKIDAILEENGVKP"
     gene            complement(52410..53276)
                     /locus_tag="ACFOV4_000204"
     CDS             complement(52410..53276)
                     /locus_tag="ACFOV4_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFC7618298.1"
                     /translation="MKAKILTSVALLACSGSLFAQTLATVNGQKIDSSVIDAQVAAFR
                     AENSRAEDTPQLRQSLLENEVVNTVVAQEVKRLKLDRSAEFKNALAKLRAEAKKSGDD
                     KKPSFKTVWQAVKYGLNGEAYALHIAKTQPVSEQEVKAAYDNISGFYKGTQEVQLGEI
                     LTDKEENAKKAVADLKAKKGFDAVLKQYSLNDRTKQTGAPVGYVPLKDLEQGVPPLYQ
                     AIKDLKKGEFTATPLKNGDFYGVYYVNDSREVKVPSFDEMKGQIAGNLQAERIDRAVG
                     ALLGKANIKPAK"
     gene            complement(53325..53603)
                     /locus_tag="ACFOV4_000205"
     CDS             complement(53325..53603)
                     /locus_tag="ACFOV4_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family protein"
                     /protein_id="HFC7618299.1"
                     /translation="MPAVDLIRERLQTLDPLVLEIGDESHLHKGHAGNTGGGHYAVLV
                     VSGRFEGVSRLNRQKTVKSLLKDLFSGGMIHALGIRAATPDEYFHTAD"
     gene            complement(53603..53893)
                     /locus_tag="ACFOV4_000206"
     CDS             complement(53603..53893)
                     /locus_tag="ACFOV4_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HFC7618300.1"
                     /translation="MEYFMLLATDGENVYEARMAARPEHLKRLETLKSEGRLLTAGPN
                     PLPEDSNRVSGSLIVAQFESLDAAEAWAEDDPYVHAGVYSEVLIKPFKAVFK"
     gene            complement(53896..54426)
                     /locus_tag="ACFOV4_000207"
     CDS             complement(53896..54426)
                     /locus_tag="ACFOV4_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HFC7618301.1"
                     /translation="MKFVSDLLSVILFFATYTVTKNMIAATAVALVAGVVQAAFLYWK
                     YKKLDTMQWVGLVLIVIFGGATIVLGDSRFIMWKPSVLFWLGALFLWGSHLAGKNGLK
                     ASIGREIQLPDAVWAKLTYMWVGFLIFMGIANWFVFTRFESQWVNYKMFGSTALMLVF
                     FIIQGIYLSTCLKKED"
     gene            54734..57259
                     /gene="tspA"
                     /locus_tag="ACFOV4_000208"
     CDS             54734..57259
                     /gene="tspA"
                     /locus_tag="ACFOV4_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_164729270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FimV/HubP family polar landmark-like protein
                     TspA"
                     /protein_id="HFC7618302.1"
                     /translation="MKNNRQIKLIAASVAVAASFQAHAGLGGLNIQSNLDEPFSGSIT
                     VTGEEAKALLGGGSVTVSEKGLTAKVHKLGDKAVIAVSSEQAVRDPVLVFRIGAGAQV
                     REYTAILDPVGYSPKTKSALSDGKTHRKTAPTAESQENQNAKALRKTDKKDSANAAVK
                     PAYNGKTHTVRKGETVKQIAAAIRPKHLTLEQVADALLKANPNVSAHGRLRAGSVLHI
                     PNLNRIKAEQPKPQTAKPKAETASMPSEPSKQATVEKPVEKPEAKVAAPEAKAEKPAV
                     RPEPVPAANTAASETAAESAPQEAAASAIDTPTDETGNAVSEPVEQVSAEEETESGLF
                     DGLFGGSYTLLLAGGGAALIALLLLLRLAQSKRARRTEESVPEEEPDLDDAADDGIEI
                     TFAEVETPATPEPAPKNDVNDTLALDGESEEELSAKQTFDVETDTPSNRIDLDFDSLA
                     AAQNGILSGALTQDEETQKRADADWNAIESTDSVYEPETFNPYNPVEIVIDTPEPESV
                     AQTAENKPETVDTDFSDNLPSNNHIGTEETASAKPASPSGLAGFLKASSPETILEKTV
                     AEVQTPEELHDFLKVYETDAVAETAPETPDFNAAADDLSALLQPAEAPSVEENITETV
                     AETPDFNATADDLSALLQPSKVPAVEENAAETVADDLSALLQPAEAPAVEENVTETVA
                     ETPDFNATADDLSALLQPSEVPAVEENAAETVADDLSALLQPAEAPAVEENATEITLE
                     TPDSNTSEADALPDFLKDGEEETVDWSIYLSEENIPNNADTGFPSESVGSDAPSEAKY
                     DLAEMYLEIGDRDAAAETVQKLLEEAEGDVLKRAQALAQELGI"
     gene            complement(57432..57848)
                     /gene="gloA"
                     /locus_tag="ACFOV4_000209"
     CDS             complement(57432..57848)
                     /gene="gloA"
                     /locus_tag="ACFOV4_000209"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004462 - lactoylglutathione lyase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0051596 - methylglyoxal catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFC7618303.1"
                     /translation="MRLLHTMLRVGNLEKSLDFYQNVLGMKLLRRKDYPEGRFTLAFV
                     GYGDETDSTVLELTHNWDTERYDLGNAYGHIAVEVDDAYEACERVKRQGGNVVREAGP
                     MKHGTTVIAFVEDPDGYKIEFIQKKSGDDSVAYQTA"
     gene            complement(57873..59042)
                     /gene="lapB"
                     /locus_tag="ACFOV4_000210"
     CDS             complement(57873..59042)
                     /gene="lapB"
                     /locus_tag="ACFOV4_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0008653 - lipopolysaccharide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HFC7618304.1"
                     /translation="MDNELWIILLPIILLPVFFAMGWFAARVDMKTVLKQAKSIPSGF
                     YKSLDALVDRNSGRAARELAEVIDQQPQSYDLNLTLGKLYRQRGENDKAINIHRTMLD
                     SPDTVGEKRARVLFELAQNYQSAGLVDRAEQIFLGLQDGKMAREARQHLLNIYQQDRD
                     WEKAVETARLLSHDDQTYQFEIAQFYCELAQAALFKSNFDVARFNVGKALEANKKCTR
                     ANMILGDIEHRQGNFPAAVEAYAAIEQQNHAYLSMVGEKLYEAYAAQGKPEEGLNRLT
                     GYMQTFPELDLINVVYEKSLLLKCEKEAAQTAVELVRRKPDLNGVYRLLGLKLSDLDP
                     AWKADADMMRSVIGRQLQRSVMYRCRNCHFKSQVFFWHCPACNKWQTFTPNKIEV"
     gene            complement(59053..59367)
                     /locus_tag="ACFOV4_000211"
     CDS             complement(59053..59367)
                     /locus_tag="ACFOV4_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly LapA
                     domain-containing protein"
                     /protein_id="HFC7618305.1"
                     /translation="MKLIYTVIKIIILLLFLLLAVINTDAVTFSYLPGQKVDLPLIVV
                     LFGAFVVGIVFGMFALFGRLLSLRGENGRLRAEVKKNARLTGKELTAPPAQNAPESAK
                     QP"
     gene            59677..60675
                     /gene="ilvE"
                     /locus_tag="ACFOV4_000212"
     CDS             59677..60675
                     /gene="ilvE"
                     /locus_tag="ACFOV4_000212"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HFC7618306.1"
                     /translation="MSRPVPAVFGSVFHSQMPVLAYREGKWQPTEWQSSQDLSLAPGA
                     HALHYSSECFEGLKAFRQADGKIVLFRPTANIARMRQSADILHLPRPETQAYLDALIE
                     LVKRAADEIPDAPAALYLRPTLIGTDPVIGKAGSPSETALLYILASPVGDYFKVGSPV
                     KILVETEHIRCAPHMGRVKCGGNYASAMHWVLKAKAEYGANQVLFCPNGDVQETGASN
                     FILINGDEIITKPLTDEFLHGVTRDSVLTVAKDLGYTVSERNFTVDELKAAVENGAEA
                     ILTGTAAVISPVTSFVIGGKEIEVKSQERGYAIRKAITDIQYGLAEDKYGWLVEVC"
     gene            complement(60860..61645)
                     /gene="fabI"
                     /locus_tag="ACFOV4_000213"
     CDS             complement(60860..61645)
                     /gene="fabI"
                     /locus_tag="ACFOV4_000213"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFC7618307.1"
                     /translation="MGFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKL
                     EERVRKMAAELGSELVFRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSG
                     DFLDSISREAFNTAHEISAYSLPALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVM
                     GMAKASLEAGIRFTAACLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLR
                     RNVTIEEVGNTAAFLLSDLSSGITGEITYVDGGYSINALSTEG"
     gene            complement(61800..62621)
                     /gene="dapD"
                     /locus_tag="ACFOV4_000214"
     CDS             complement(61800..62621)
                     /gene="dapD"
                     /locus_tag="ACFOV4_000214"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008666 -
                     2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HFC7618308.1"
                     /translation="MSLQNIIETAFENRADINPTTVTPEVKEAVLETIRQLDSGKLRV
                     AERLGVGEWKVNEWAKKAVLLSFRIQDNEILNDGVNKYFDKVPTKFADWSEDEFKNAG
                     FRAVPGAVARRGSFVAKNVVLMPSYVNIGAYVDEGAMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQASPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIFDRT
                     TGEIYQGRVPAGSVVVSGSMPSKDGSHSLYCAVIVKRVDAQTRAKTSVNELLRGI"
     gene            complement(62788..64431)
                     /gene="pgi"
                     /locus_tag="ACFOV4_000215"
     CDS             complement(62788..64431)
                     /gene="pgi"
                     /locus_tag="ACFOV4_000215"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFC7618309.1"
                     /translation="MNAFTRAWYALERHYQDTRHVLLRDRFACEPDRFERMHERLDGM
                     LFDYSKNRLGEDTLQLLCRLAETADLEGKMRALRTGAKVNGSEGRAALHTALRLPDGA
                     DAVYADGRDVLPEIRRELNRALEFAHSLDDGSYQGTTGKRITDFVHIGIGGSDLGPAM
                     CVQALEPFRRHITVHFAANADPACLDAVLCRLNPETTVFCVASKSFKTPETLLNAQAV
                     KAWYRGAGFSESETACHFCAVSADTAAAAAFGIAAERVFAMYDWVGGRYSVWSPVGLP
                     VMVAVGGARFRELLAGAHAMDSHFFHTPPRRNIPVLMALIAVWYNNFQHADGQTAVPY
                     SHNLRLLPVWLNQLDMESLGKSRASDGSPAVCKTGGIVFGGEGVNCQHAYFQLLHQGT
                     RLIPCDFIVPMTAQGVEDGRSRFTVANAFAQAEALMKGKTLDEARAELADLPEAERER
                     LAPHKEFPGNRPSNSILLDRLTPYNLGMLMAAYEHKTFVQGAIWNVNPFDQWGVEYGK
                     QLAKTIIGELEGGTSVHDASTEGLMAFYRECRLKGGGAA"
     gene            64941..66173
                     /gene="pilG"
                     /locus_tag="ACFOV4_000216"
     CDS             64941..66173
                     /gene="pilG"
                     /locus_tag="ACFOV4_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4 pilus assembly protein PilG"
                     /protein_id="HFC7618310.1"
                     /translation="MAKNGGFSLFAKKEKRFIFEGRHSASDKLVNGEVSAFTEEEARK
                     KLAKRGIRPLQITRVKTSSKRKITQEDITVFTRQLSTMIKAGLPLMQAFEIVARGHGN
                     PSMTEMLMEIRGEVEQGSSLSRAFSNHPKYFDRFYCNLVAAGETGGVLESLLDKLAIY
                     KEKTQAIRKKVKTALTYPVSVIAVAIGLVFVMMIFVLPAFKEVYANMGAELPALTQTV
                     MDMSDFFVSYGWMVLIALGFAIYGFLKLKARSIKIQRRMDAILLRMPIFGDIVRKGTI
                     ARWGRTTATLIAAGVPLVDVLDSTAGAAGNLIYEEATREIRTRVIQGLSMTSGMRATE
                     LFPNMMLQMSSIGEESGSLDDMLNKAAEFYEDEVDNAVGRLSAMMEPIIIVILGLVIG
                     TLLVAMYLPLFNLGNVVA"
     gene            66247..67107
                     /locus_tag="ACFOV4_000217"
     CDS             66247..67107
                     /locus_tag="ACFOV4_000217"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFC7618311.1"
                     /translation="MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVF
                     AKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAWQNIPIVSYLLLRGKCASCQTKI
                     SIRYPLIELLTGVLFGLVAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLP
                     LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAAL
                     GAWLGISALPVLIFVSSLIGLVAAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRA
                     VNWWLTHPVL"
     gene            67109..67741
                     /gene="coaE"
                     /locus_tag="ACFOV4_000218"
     CDS             67109..67741
                     /gene="coaE"
                     /locus_tag="ACFOV4_000218"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258461.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFC7618312.1"
                     /translation="MTVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDG
                     IALPEIRRLFGDTVFDTQGLLRRDILRKEVFASPSRKALLESVMLPLIFSEIKKQQET
                     FTDAAYGIVEIPLLTEKRQFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVADIISH
                     QASESERLLLADDVLLNDGSLKSLREKTMRLHAFYSGIFASKPTQGKHND"
     gene            67734..67943
                     /locus_tag="ACFOV4_000219"
     CDS             67734..67943
                     /locus_tag="ACFOV4_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HFC7618313.1"
                     /translation="MTESRQTRLQVKCPTCQTAVVWEPENAFRPFCSQRCKLIDLGGW
                     ADGKYTVSGQTESLPEISEPDMAYR"
     gene            complement(68028..69704)
                     /gene="pilB"
                     /locus_tag="ACFOV4_000220"
     CDS             complement(68028..69704)
                     /gene="pilB"
                     /locus_tag="ACFOV4_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV-A pilus assembly ATPase PilB"
                     /protein_id="HFC7618314.1"
                     /translation="MSVGLLRILVQNQVVTVEQAEHYYKESQAGKEVLPILFSDGVIS
                     PKSLAALIARVFSYSILDLRHYPRHRVLMGVLTEEQMVEFHCVPVFRRGDKVFFAVSD
                     PTQMPQIQKTVSAAGIEVELVIVEDDQLAGLLDWVGSRSTSLLQELGEGQEEEESHTL
                     YIDNEEAEDGPVPRFIHKTLSDALRSGASDIHFEFYEHNARIRFRVDGQLREVVQPPI
                     AVRGQLASRIKVMSRLDISEKRIPQDGRMQLTFQKGGKPVDFRVSTLPTLFGEKVVMR
                     ILNSDAASLNIDQLGFEPFQKKLLLEAIHRPYGMVLVTGPTGSGKTVSLYTCLNILNT
                     ESVNIATAEDPAEINLPGINQVNVNDKQGLTFAAALKSFLRQDPDIIMVGEIRDLETA
                     DIAIKAAQTGHMVFSTLHTNNAPATLSRMLNMGVAPFNIASSVSLIMAQRLLRRLCSS
                     CKQEVERPSASALKEVGFTDEDLAKDWKLYRAVGCDRCRGQGYKGRAGVYEVMPISEE
                     MQRVIMNNGTEVDILDVAYKEGMVDLRRAGILKVMQGITSLEEVTANTND"
     gene            complement(70103..70174)
                     /locus_tag="ACFOV4_000221"
     tRNA            complement(70103..70174)
                     /locus_tag="ACFOV4_000221"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(70139..70141),aa:Arg,seq:cct)
     gene            complement(70194..70640)
                     /locus_tag="ACFOV4_000222"
     CDS             complement(70194..70640)
                     /locus_tag="ACFOV4_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFC7618315.1"
                     /translation="MNFSFVPLFLVTLILLGVVSNNNSITISATILLLMQQTALVQFV
                     PLVEKHGLNLGIILLTIGVLSPLVSGKAQVPPVAEFLNFKMISAVFIGIFVAWLAGRG
                     VPLMGQQPVLITGLLIGTVIGVAFMGGIPVGPLIAAGILSFVVGKG"
     gene            complement(70645..71619)
                     /gene="ispB"
                     /locus_tag="ACFOV4_000223"
     CDS             complement(70645..71619)
                     /gene="ispB"
                     /locus_tag="ACFOV4_000223"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HFC7618316.1"
                     /translation="MLENLPYFQRHLPEDLAKVNEVINRAVQSDVALISQIGTYIISA
                     GGKRLRPIMTILAGKAVGYDDEKLYSLAAMVEFIHTSTLLHDDVVDESDLRRGRATAN
                     NLFGNAAAVLVGDFLYTRAFQLMVASGSMRVLEVMADATNIIAEGEVMQLMNIGNTDI
                     TEEQYIQVIQYKTAKLFEAAAQVGAILGKASPEHERALKDYGMYVGTAFQIIDDVLDY
                     SGETEETGKNVGDDLAEGKPTLPLIYLMRQGSEQVANDVRTALENADRSYFEKIHDYV
                     VRSDALAYSIGEARKAVDCAVTALDALPDSEVKDAMIQLAKESLVRVS"
     gene            71843..72151
                     /gene="rplU"
                     /locus_tag="ACFOV4_000224"
     CDS             71843..72151
                     /gene="rplU"
                     /locus_tag="ACFOV4_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFC7618317.1"
                     /translation="MYAVVKTGGKQYKVSVGEKLKVEQIPAELDSQIELTEVLMIADG
                     ESVKVGAPFIEGAKVTAKVVAHGRGEKVRIFKMRRRKHYQKRQGHRQNFTQIEIVAIA
                     "
     gene            72176..72448
                     /gene="rpmA"
                     /locus_tag="ACFOV4_000225"
     CDS             72176..72448
                     /gene="rpmA"
                     /locus_tag="ACFOV4_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFC7618318.1"
                     /translation="MASKKAGGSTRNGRDSEAKRLGVKAYGNELIPAGSIIVRQRGTK
                     FHAGDNVGMGKDHTLFAKVDGYVEFKTKGALNRKTVSIRPYTGSEE"
     gene            72836..74020
                     /gene="ubiM"
                     /locus_tag="ACFOV4_000226"
     CDS             72836..74020
                     /gene="ubiM"
                     /locus_tag="ACFOV4_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016709 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, NAD(P)H as one donor, and incorporation
                     of one atom of oxygen [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-demethoxyubiquinol-8 5-hydroxylase UbiM"
                     /protein_id="HFC7618319.1"
                     /translation="MSLHSDILVVGAGPAGLSFAAELAGSGLKVTLIERSPLTVLQNP
                     PYDGREIALTHFSREIMQRLGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARG
                     EPADCLGYLISNHNIRRAAYEVVSQLDNITILTDTAVKEVKTSDNEAQVILENGKILT
                     ARLLLAADSRFSQTRRQLGISSDMHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIAL
                     LPLEEHLTNTVITVDTDKINSVQNLSPEELAASVKEQLKGRLGDMELVSSIHHYPLVG
                     MIAKRFYGKRSALIGDAAVGMHPVTAHGFNLGLSSADILAKLILEAEQRGQDIGASSL
                     LEKYSNKHMLHAHPLYHGTNMMLKLFTNETAPAKLLRGLVLRAGNNFPPLKKLITKQL
                     TG"
BASE COUNT        18705 a        19931 c        18477 g        16950 t
ORIGIN      
        1 cgcgggaatg acgaatccat ccgcacggaa acctgcacca cgtcattcct acgaatctac
       61 atcccgtcat tcccacaagg acagaaaacc aaaatcagaa acctaaaatt cgtcattccc
      121 gcgaaagtgt gaatctagaa atgaaaagca acaagcattt atcgaaaata actgaaaccg
      181 aacagactag attcccgcct gcgcgggaat gacgaatcca tccatacgga aacctgcacc
      241 acgtcattca cacgaaagtg ggaatccaag acgaaaaatc tcaagaaacc gttttacctg
      301 ataagtttcc gcaccgaccg gtctggattc ccgcctgcgc gggaatgacg gttcgggtat
      361 ttctgatgat tcggcgagcc gtagcaactg tatttttcac cccgtcgggc aaaaatacca
      421 aaactcaaat caagccgtcc ggataccgtt ttcggcggta tcgttttcgg cggtatcgtt
      481 ttcggcaaaa taatcacgca tccgggcatt cgatatcgtc agcagtttgc gcatacatgc
      541 cgtaacggca accttatacg gcttaccctc ggacggcagg cgttggtaga aatcccgaat
      601 aagcggttca aaacgtgtcg ctgccacggt agccatatac agtgccttac gcaccgcaga
      661 ccttccgcca aagcagcggc ttttgaattt ggtttccccg ctctccctcg ggtgcggggc
      721 aatgccgacc aaacccgcta tccgtttgtg cgacagccgc cccaattcgg gtagcattgc
      781 catcagcgta gccgtcgtta tcgaaccgat gcctttgatt tgttctgcca cttgggcttt
      841 gccgtcaaaa tgcgtgtggg tgtggtcgtc gatttgtttg tccaattcgt caatcagccg
      901 gtcaaaatgg gcaatcagtt gtttgacgct tccgacttgc gtttcatgaa actgatgcag
      961 atatagtgga ttaacaaaaa tcaggacaag gcgacgaagc cgcagacagt acaaatagta
     1021 cggcaacgct gtactggttt aaatttaatc cactatattt tgtaatagct gccattatgc
     1081 ctactaggat atataccttc tatataatcc ttatttaaat aaaaaccctt ataaaaatct
     1141 gtgttatctg tcgggattga aaaaaagatt ttatctttct catcaggttt atatttgcta
     1201 tcaatatcaa aaagagaata aggattacaa tgagttcgac atactaggta aaaatttata
     1261 tcttggatca tgaaatattc gatatttatc aggatcgaaa gatgctaaaa attcatcaat
     1321 attggtactg gatattttgt catcactaat aaacatcgct agagatgggc gactttgatt
     1381 ttccatttgt tgattagtaa aggatataaa tactaacttg ccattgtcaa accacataga
     1441 tttatatagt ggattaaatt taaaccagta cgtcgttgcc tcgccttgcc gtactatttg
     1501 tactgtctgc ggcttcgtcg ccttgtcctg atttttgtta atccactata gttattgcct
     1561 ttgggagaat caattctgac agcacataac ataggttcat ctttacagtc gttatattgg
     1621 gtttcatcaa actcaactgc atagcacaat aaaggcaata ggaaaaaaag gagattaatt
     1681 tattactata cataaggcag cctgactatt cattctaaaa taaatccggt ttttaatatt
     1741 tgattctgct ccggattata tacataataa attttactgc tccaaaatct gatattaacc
     1801 ctatggattt cataaatttt tcagaaaaat aggctgtgct tgaacaatcc gccgactccg
     1861 gctgtttgtc agggaaaagg caattatttt cggttagtca gcagcctatc ctattgaatc
     1921 acttaaagat atggatgttt gtcaacgcca tatcaaaaca cggtctttta ccaatcgaat
     1981 tctgccgtca ccggcgcgtg gtcgctcgga cgctccagcg cgcgcgtctc caaatcgacg
     2041 cggacatcct tcaacgccgc cgccatcgca ggcgacacca aaatatggtc gatacgcagg
     2101 cccagtttgc gttggaacat cgcgccgcga tagtcgaacc aggtatagaa cgcgccttcg
     2161 ggatggactt ggcgcaggct gtcggtcagt cccaaatcca gcaggttttg aaaccactgc
     2221 cgttcgacgg acgaacagtg gattttttcg tgccattttt cagggtcgta acagtccgca
     2281 tcggcaggcg cgatattgaa atcgcccagc aacaccagtt tgccgtggcg ggtcatttca
     2341 tcgcggacaa actccgtcag tgcggcaaac cactgttcct tatatttgaa tttggggctg
     2401 tccaaagcct cgccgttgac gcaatagaca ttgatgacgc gcacgccgct gacggttgcc
     2461 gcaatcacgc gccgttgcgg atcgtccggc agtgcgggca aaccgaaatg cacgtcctgc
     2521 ggcacgctgc ggctgacgat tgccacgccg ttgtaggttt tctgcccgct ccaaacacag
     2581 tgccagccca tcatttgcaa agcggcggcc ggaaatttgt cctgatcgag tttgagttcc
     2641 tgcaaaacca aaatatcggg cggattgtcg gcaagcaggt tttgcacctg cggcagccgc
     2701 acattgagcg aattgacatt ccaagtggtg attttcataa catttccgaa aaatgctgtc
     2761 tgaaacgttc agacggcaaa aggaaaggat tctaacacta tgccacgcgt ttgttttcca
     2821 aatcgcgaac cgtgtgcaga atcgccgccg cttcttcgga aaccaggcgg tattcgataa
     2881 tgcggtggta acgcgtaaaa tcgactagac cttccacgcg caggcggttc aaatggttgg
     2941 aaactgcggt ggccggcagg gataaggatt ttgccagttc ggcgatattg cgttcgctgt
     3001 ccaacaattg aatcagtatc gccatacgtt cgggatgcgc cataagtttg agtatggtgt
     3061 ggagcggtat tgtgttcatc ggtattccta aaacctttgc cgcccgccaa gcggattgac
     3121 gggcggcaga tatggatgat tgtgattatc tttataaatc gtattataaa tcaaatattt
     3181 atggatgatt gtacaggatt gtatgttcct tttcccactt ttttgcaaac aagcgtaaag
     3241 gcgggctttc agacggcata aaactgccgc cccccgtcct ttttcctgcc ctaccgatgc
     3301 cgccgcgctg tcgggcaaac aaaatacctg cctgaaatgc tgttttttct aaagcatcac
     3361 gacctttacg aaaaatgccg tctgaagaat ctttcagacg gcatttcctc cctgaggcaa
     3421 taaccggatt agggttaagc ggttccttgc ctgacatatc agacagccgc ccgcacccta
     3481 aaactcacgc cacgaaatcc aaacctatgt ccaacgaacg gctgctgtgg gtcagatagc
     3541 cgagggcgat gccgtccact ccggtttgcg ccacgcgctt caggcggtcg aagccgatgc
     3601 cgcccgatgc ttcgcaatag atggtgtggg ggtgggcggt ttgcgtgtgg cagcggtttg
     3661 ccgcttcttt cagggtttcg tcgtccatgt tatccagcaa aatccgttcc gcgcccgctg
     3721 cgatggcttc gtccagttgt gccaacgtat ccacttcgat ttccacgcag gtcaatgctc
     3781 cgacagcctg ttttgcctgc tgcacggctt gggcgatgct gccgcaatag gcgaggtggt
     3841 tgtctttgat gagcacggcg tcgtccaaac ccatgcggtg gttcacaccg ccgcctgccc
     3901 tgacggcgta tttttgcagg acacgcagca gggggatggt tttgcggctg cacacgatgt
     3961 ctgtaccgta ttcggcgact tcggcaacgg cacgcgcggt ggcggtggcg atgccgctta
     4021 agtgcgtgag gtagttgagc gcggtgcgtt cggcggcgag cagcgcgcgg gcgttgcctt
     4081 cgacggcggc aagcgtctga cctgcgcgga cggcttgccc gtctcggatt tcggcttgga
     4141 agcggacgga cggatccatc gtctgaaagg cgaggcgcgc taaatccatg ccggcgataa
     4201 cgccgtcttc gcggctgacg aggaagagtt tggcggtttt gtcgggggcg ataacggcgg
     4261 cggacgtaat gtcgccgcgc ctgcccaagt cttcgctcaa ggcttgttcg actatggggc
     4321 gcaacagggt gtcgggcagg gaaaagaggg tgttttcaga cggcatgagg tttcctttgt
     4381 cgaaaaagat tgatgttgca ccgatggggc aaaacttcat ttgatgccgt ctgaaaacgg
     4441 gctaacggct gcccagcggc aatccgatgt ccgaaatcag cctgtcgggc aggacgtcgt
     4501 cgcggaagcg gcaaagctgc gcgggacggc ctttgctgcc cgatacgccg gtatccgacg
     4561 gctcgataag gttttgctgc tgaatctggc ggcggaagtt ttgcttgtgc agcaatcttc
     4621 cgctgatggc ttcgacactg ttttgcagtt gcagcagcgt gaattcgggc ggcatcagtt
     4681 caaaaatcac ggggcggtat ttgattttgg cgcgcaggcg ggacagggcg gtcgccagta
     4741 cgcgacggtg atcgtggcgc atgggctgcc ccgtgagcgc gaagtcgaag tttgcctgcg
     4801 gctcggcggc ttccactatc agaccgcttt catacagcat ttcatagcgt tgtaaaacgt
     4861 attcttccga ccagttttcc ggttcgaccc cccagcacaa atgaatgcgc ttgagccgca
     4921 tttgacgcac ttcctccgtg tccgccgaat ttgcccaaat gcgcaggcgg ctgacgacgg
     4981 cgtcgcgctg cccgccgtcg gtgcgcaagt cttcccacgg gaaatagccg tagcagtcct
     5041 gccatttcgc atccgggtgc aggatgctgt cggctgcctc gcgcaccagc cccaaatagc
     5101 tgacgtacaa gacgggcatg ccgtgttcgt tgcggcggtg ggtatcgaca aaggtgtaaa
     5161 gctgttccac atagcccata ggctgcgaag tctgcttggc aacccacagc ttcacgcccg
     5221 cctgcaggga attgcgcaga ggggagagcg ggccgttggg caggagtgtg ccttgggcga
     5281 cggttaatac ccgcaggccg ccgtcggtaa cggcaatcaa tacgggaacc agctcgacga
     5341 tgctttgcgg cggggcttcg gcttcggggt aggcatccat gctcggcttt ctgcgggtgg
     5401 gaaaggcttt attgtatagt ggattaaatt taaaccagta cagcgttgcc tcgccttgcc
     5461 gtactatttg tactgtctgc ggcttcgtcg ccttgtcctg atttttgtta atccactata
     5521 aaccaaagcg gtttgtcgga acgaagcggg tcggttttac ggtatcgcaa acctgttttc
     5581 agacgacctt gcttattata ctcaatttga gcataatata aaaatatttc aaaatataaa
     5641 cggcaaatct ttatgccgtc tgaaaaacca gccataagga agtctcatgc aaaccgccgc
     5701 ccgccgctcg ttcgattacg atatgcccct catccaaacc ccgacttccg cctgccaaat
     5761 ccgtcaggcg tgggcgaagg ttgccgacac gcccgaccgc gagacggcag gccgtctgaa
     5821 agacgaaatc aaggctttgc tgaaggagaa aaacgcggtc ttggtggcgc attattacgt
     5881 cgatccgctg attcaggatt tggctttaga aacgggcgga tgcgtgggcg attcgctgga
     5941 aatggcgcgc ttcggcgcgg aacacgaagc tagtacattg gtggtggcgg gtgtgcgctt
     6001 catgggcgag agcgcgaaaa tcctctgccc tgaaaaaaca gtgctgatgc ctgatttgga
     6061 ggcggaatgt tctttggatt tgggctgtcc ggaagaagcg ttttcagcgt tttgcgacca
     6121 acaccccgac cgcacggtcg tagtgtacgc caacacttcc gccgccgtga aagcgcgtgc
     6181 cgattgggtg gtaacgtctt cggtggcgtt ggaaatcgta tcgtatttga aatcgcgcgg
     6241 cgagaagctg atttggggac ctgaccgcca cctcggcgac tacatccgcc gcgaaacggg
     6301 cgcggatatg ctgctgtggc agggttcgtg catcgtccac aacgaattca aagggcagga
     6361 gctggcggcg ttgaaggcgg aacaccccga agcggtggtg ctggttcatc ccgaatcgcc
     6421 acaaagcgtc atcgaactgg gcgacgtggt cggctcgacc agcaaactgc tcaaagccgc
     6481 cgtatcgcac cctgaaaaaa aattcatcgt agcgaccgac ttgggcatcc tgcacgaaat
     6541 gcaaaagcag gcacccgaca aagaatttat cgccgcaccg acggcgggca acggtggaag
     6601 ctgtaaaagc tgcgcgttct gcccttggat ggcgatgaat tcgctgggcg gcatcaaata
     6661 cgccctgaca agcggacaca acgaaatcct gttggacagg aagctgggcg aagccgccaa
     6721 actgcctttg cagcgtatgc tcgacttcgc ggcaggactc aagcgcgggg atgtgttcaa
     6781 cggcatggga cccgcctgat ttgccgtcca tattatagtg gattaacaaa aatcaggaca
     6841 aggcgacgaa gccgcagaca gtacaaatag tacggaaccg attcacttgg tgcttcaaca
     6901 ccttagagaa tcgttctctt tgagctaagg cgaggcaacg ccgtactggt ttaaatttaa
     6961 tccactatac cgtttcagac gatctctcaa acaaggacaa caccatgcaa accgattgcg
     7021 acgtattgat tgccggaaac gggctggcgg cactgacgct cgccctgtcg ctgcctgaat
     7081 cgttccgcat cgtcattttg tgcaaaaacc ggctggacga cactgccagc cgtcatgcgc
     7141 aaggcgggat tgcggcggcg tggtcgggag aggacgacat cgaaaaacac gttgccgata
     7201 ccttggaggc gggcgcgggt ttgtgcgacg aagccgccgt ccgcaccatc ctgtcgcagg
     7261 gcaaactggc aatcgaatgg ctgctggcgc agggcgtggc gttcgaccaa aataataacg
     7321 gcctgcacct gacgcgcgaa ggcgggcaca cctgccgccg aatcgcccac gtcgccgact
     7381 acacgggcga agccgtcatg cagagcctga ctgtccaaat acgctgccgc ccgaacatcc
     7441 gcgtttgcga gcagcagatg gcgttggaca tccaaaccga atcaggtgcg gcgtgcggac
     7501 tgaccgtcct cgactgccga acgcaagcaa cctacagcat ccgcgcccgc cataccgtac
     7561 tcgcaggcgg cggcttggga cagatttacg ccgccaccac cacgccgccc gaatgcacgg
     7621 gcgacgccat cgccatggcg atacgcgcag gctgcgcagt cgaaaacctc gaatttatcc
     7681 aattccaccc cacaggcttg gcaagatcgt ctgaaaacgg ccgcaccttc ctgatttccg
     7741 aagccgtgcg cggcgaaggc ggcatcctga ccaaccaagc gggcgaacgg tttatgccgt
     7801 attacgaccg ccgcgccgaa ctcgcgccgc gcgacatcgt tgcccgcgcc atcgccgccg
     7861 aaatcgccaa acaaacgcaa gacttcgtct cactcgatat cagccatcaa cccgcagcgt
     7921 tcgtccgccg gcatttcccg tccatccatc ggcactgttt atcccaatgc ggcctggata
     7981 tcacgcgcca agccatcccc gtccgccccg tgcaacacta cacctgcggc ggcatccaaa
     8041 ccgacccctg cggcagaact tccctgccgc agctctactc cttaggcgaa accgcctgca
     8101 ccggcttgca cggagccaac cgccttgcca gcaactccct gctcgaatgt gtcgttaccg
     8161 ccagacttgc cgcccaaacc atcgcagacg gacaagcatt ccaagccaaa acgtctccaa
     8221 ggccgtctga aagcctctcc tccgaagcag gcatcttttc agacggcatc caaagcgcat
     8281 tcagccgccc cgtcctgcaa gcgttcaacc aacgccatct aggcatcctc cgcaacgata
     8341 ccggtctgcg ctgcgccatc gcccagctgc ggctttggaa acaaaaccaa accgaaccgc
     8401 acaccgcgtc cgaatacgaa aaccgcaacc tgctcgaatg cagcctcgcc gtcgcccaag
     8461 ccgcatacag gcggagacag aacatcggcg cgcattttaa tagtgattgt taaggttggc
     8521 tggttagaaa aaaaatcgtt caaataaatt tgaatagcat ggttaagaaa ttggcattta
     8581 gtttttaggg ttgcgtaagt tgggttatca atctgttcta aaagcagaaa ggccgtctga
     8641 aacactgttc agacggcctt ttacttcctt gacactttat ctgacgcgtt ttacctgccc
     8701 gactgtgccc acacgttttg caggtaggcg taggtcagct cggcggtatc ggacaccagc
     8761 gcgatgtcgc tgcccaagtc ttcggctttg cccacgccga taggcaaggc gccggcggct
     8821 ttgatggcgg cgacacctgc ggcagcgtct tcaatgccga tgcagcggcg gatgtccgcg
     8881 cccacgccct cggcggcggc gaggaagatg tcgggggagg gtttggaatg cgcgacggcg
     8941 gcagggtcgg cgacggtgtc gaagaagtgg gtcagcccca tgcgttcgag caggaagggg
     9001 ccgtttttac tggcggacgc aagggcgatt tttttgccgt ttgcttttaa tgcttccagc
     9061 agcggcaaaa tgccgagata cacgtcttcg ggtttgactg cctgtatcat ctccaagtag
     9121 ttgtcgtttt tgcggcgggt cagttcggcg aactcggctt cgccgacggt tttaccgccg
     9181 tgcgcgagga tgcgtttgag cgaatcgtcg cgcgacacgc ctttgagctg ctcgttaaac
     9241 ttgcggtcga tgccgatgcc cagttcttcg gcgagttttt tccacgcgcg gtagtggtat
     9301 tcggcggtgt cggtgatgac accgtcgaga tcgaagagga ctgcggtaaa cgtcattttg
     9361 caccctcctt atttttccaa cgcggcggcg tggctgccgt cgagcgtgat gtctttgcca
     9421 tacacctgca aatcgagcgg ctcgcctttg agcagggtga agacgacgtt ttctttgccg
     9481 acggcgactt taatcagacg gcctcggtag ttgatatgga aggcgtagcc tgtccatgcg
     9541 cccggcagga acggtgcgaa gctgagttta ccgccccaag ttttcatttg ggcgaaacct
     9601 tggacgatgg cgagccacga gccggtcata gaagtaatgt gcaggccgtc ttcggtgtcg
     9661 ttgttgtagt tgtccaagtc caggcgggcg gtgcgctggt acatttccac ggctttttct
     9721 tctttgccca gttcggcggc gagaatagag tggatacaag gcgacaacga gctttcatgc
     9781 acggtcatcg gttcgtagaa gtcgaagttg cggcgttttt cgtcgatatt gaaacggtcg
     9841 ccgaagaaat agatgccttg caatacgtcc gcctgtttga taaagggcga acgcaggatt
     9901 ttgtcccacg accatttctg gttgagcggc aaatcgtcgg gcgaaagcgc ggacacgggg
     9961 cggatgcctt tgtcgaggaa gccgtcgtgt tgcacgaata cgccgagttc ttcgtcatac
    10021 ggacggtaca tattcgcgct gatgtccgcc catttttcca actcggcggc gctcacgttc
    10081 aaatccggac gcgggtattt cgccagggct tcgcgggtgt agtccaatac ccatgcggcg
    10141 agggtgttgg tgtaccagtt gttgttgatg ttgttttcgt attcgttcgg gccggttacg
    10201 ccgtgaatca tgtatttgcc gctgcgtttg gagaagtgga cgcggtccgc ccagaagcgg
    10261 gacacttcga ccaagacttc caagccttct ttggcaagat agccctcgtc gccggtgtag
    10321 ttggtgtagt tgtagatggc gtaaggaatc gcgccgttgc ggtggatttc ctcgaaggtg
    10381 atttcccatt cgttgtggca ctcgatgccc gtaaacgtta ccatcggata gagtgcgccc
    10441 gccaagccct gttcgcgcgc gttgtgttgc gcctgtggca gttggttgcg gcggtattgc
    10501 agcaggttgc gggtaacttc gggttccgcc agtgcgaggt agagcggcac ggcgtaggct
    10561 tcggtgtccc aataggtcgc gccgccgtat ttttctccgg taaagccttt cgggccgatg
    10621 ttcagacgcg cgtcttcgcc gtagtaggtg gagaacagtt ggaacagatt gaaacggatg
    10681 ccttgctgcg cttcgtcgtt gccttcgatg accacgtcgg cgatttccca acggtgcagc
    10741 cagcctgctt tgtgcgcgtc cagcaaggtt tcaaacacaa cgcctgcgac tttttccgac
    10801 aaggcgcggc ctgcggcttt cactgcttcc aagccctgat aatcgcggct ggtggtaaca
    10861 ataacccgtt tttcaaaggt tttgggcgtg ccgccgactt cgacctcgaa agaattggag
    10921 acttgccagt cggtttggct gccgctgagg gctttgaagc tgccggcgaa agtttgctcg
    10981 gcgttgacga taaattgttc cacgccgaaa gggttggcaa cggtttgggc ggcaatgtag
    11041 gagagactgt ctgaaacgcc tttgtccaat acctgccaga atttttcttc gtagttggag
    11101 tcttcgtttt tcacgtcggc atcgatgatg gaatcgatgc ggacttggtg ggttttgccg
    11161 tcaacggata cggcttccca gcggataacc gccagctctt tttgcgcgac ggacaggaat
    11221 ttgcacacat tgaaacgcac accgaatacg gtgaacgagc ggcgcaacac gccgtgctgc
    11281 atatcgagtt cgacggagaa gccggcaaca tcgtttttcg ccaagtccac ctcttgtccg
    11341 tcgacaaaga ttttgacttt gctgaaattg agcgcgttga tggctttacc gaaatatttg
    11401 gggtagccgt ttttccacca gccgacgcgg gttttgtcgg gaaaccacac accggcgatg
    11461 taggtaccca agtggctgtc ggcggaatag gtttcctcaa agctgccgcg catacccata
    11521 tagccgttgc ccaaactggt caggctctct tgcagccgtt tgtgttcttt ttccagcttt
    11581 gccgaacgca gcgtccaagg gctgatttcc ataattcttg tgtacattta tgaagctcct
    11641 gtttggattg atttgaggga atggtgaaat cttatagtgg attaacaaaa atcaggacaa
    11701 ggcgacgaag ccgcaaacag tacaaatagt acggaaccga ttcacttggt gcttcagcac
    11761 cttagagaat cgttctcttt gagctaagcc gaggcaacgc cgtaccggtt tttgttaatc
    11821 cactataaaa aggccgtctg caaccggtgt taggaagctc ctaagaaagg gattcgatgc
    11881 cgtaagcaat cgtcgcctcc ctagtatcac ccttgttcag acgaatattg ccgaactcgg
    11941 gccaattcag gctgtcgggc agcgtctgcg cctcggtcgc cagcgcgtcg taaacgcccg
    12001 catcgtgccg cgcgaaatcc tgcggggcgg cggtaaagat gaccaagccg ttgcggtcgc
    12061 tgtatatgct gatacgacgg cggcgtccgg cttgcaacac agcggcggga cggcctatat
    12121 cggacggcac gcggtaagcg tcgtcaaaac cggcccgacc cgtttcgcgg cgcagggcgg
    12181 caacggcggc atccagcggc ttgggccggc tgaaatcaaa tacttcgagg tcgtctgaaa
    12241 ccgttgagac gggcagtttt tcggcatcgg ccggaatatg tccgccctgc ggaatatgca
    12301 gaaccgcatc gtgcaggccc gcgtccagcc gccagtaaat gtgcagcgtc gggtcgaaca
    12361 ccgtgtcgcc gagcgcggtg gcgcgatagg taacggtaag ccggtcgtcc tcgtccaagc
    12421 ggtaggaaat atccaaatcc aaatcgttgg gataaccgtc ggccgactgt tgcaggcggc
    12481 tgcgcagcac caccgaacgg ccgtctgccg ccaccgcgtt gaaacgggta acggccagcc
    12541 cgtgcgaacc gccgtgcagc gcgttcctgc cttcgttggc ctccacgcgg taagtcctgc
    12601 cgttgatgtc gaacgccgca ccgcggatgc gtccggccac gcgccctatc tgcttgttaa
    12661 tctgaaacgg attgtccgca taggaagccg catcgtcgaa cgacaccacg aggttttcgc
    12721 gcacgccgtc tgccaaaacg gaaaattcct gcacaatccc gcccaagtcc agcacgcaga
    12781 cacgcgtacc acgccggttg gacagcacat agccggttac ggcacgcccg tcgatcaggc
    12841 cgaaatcgcg ggtagcgggg gtatcgctca tcgctcaaac cccgccgtgt gtttctttaa
    12901 tcaggaacac ggaaaacgcg cccagcagca ggacgacgcc ccctaccaag aacatagtgg
    12961 cctgcaagcc gcccagcata gggaaaagca cgaaactcaa cagcgaagcg acgatttgcg
    13021 gcatacagat agagccgtta aacaggccca agtaagtgcc catatgcttg cccgacaagg
    13081 cgttggttac aatcgtcagc ggataagtga taatgcccgc ccaagcgatg ccgattaagg
    13141 tataagacaa caccagcgcg tattggttgc cgatgaagaa aacggagaaa aagccgagcg
    13201 cgcccaaagc caaacagccg aaataacccg ccttatggta tttattcggc actttcgcca
    13261 atacaaacga acaaatcacc gccgcaaccg actgcaccgc cgccaaaacg ccgtaccagt
    13321 tgcccgcctc ctgataacct acggaagacg catcggtggt gtgccagacg ttttccgcaa
    13381 tcgcgcctgc cgagtaagtc cacatatatt ggaaggcgaa ccagcagaaa aactgtacca
    13441 gagtaaccgt ccaaaacgct ttaggcgcgg tttttaagag ttcgaaccag ttggcttttt
    13501 cctgattcgc ggcgacatcg atgccgtggt aacgggcgta ggtttccgga tcgtattcct
    13561 tcactttgaa aatcgtgaac gcgctggtaa tcaccagcaa cgccgcaccc acataaaacg
    13621 ccacgaccac ggtctgcggc acaacgcctt tctcggcggt gttcgccaaa ccgatatacg
    13681 caaacacaaa cggcagaatc gccgccacga ccgcgcccgt attcgctaag aaactttgaa
    13741 tcccgtaggc gtagcctttc tgctcctcgt tgaccatgtc gccgaccatc atcttaaacg
    13801 gctgcatcgc catatttgac gacacgtcca acagcgcaat catcagcgcg ccgaacgaca
    13861 aagccgccag cgacgcatag ccgaaaccga agctgcccga gttcggcatc aaaatcatca
    13921 caataaccgc aatcagcgtg ccataaagca gatacggcag acggcggccg cccaaacgcg
    13981 gcttccaagt gcggtcggag taatggccga caatcggctg caccagcatc cccgccagcg
    14041 gcggcaggat gaaaaaccag cccaaattgt gcgggtctgc gcctagcgtt tgaaaaatgc
    14101 ggctcatttg cgagctttgc agggtaaagg ccgtctgaac gccgagaaag ccgaaactga
    14161 gcatccaaat cgtgcttttt gccagcgcgg gcaaaccttg ttttgctgtt tgaggcgtat
    14221 attccgacat aaggtaaatc cttttttgat ttgaaaagta tagtagatta acaaaaacca
    14281 gtacggcgtt gcctcgcctt agctcaaaga gaacgattct ctaaggtgct gaagcaccaa
    14341 gtgaatcggt tccgtactat ctgtactgtc tgcggcttcg tcgccttgtc ctgatttttg
    14401 ttaatccact atatttgctt tggaaaatcc gaaatggttg ccggggcggc gatcccctat
    14461 cattattatt tttttgtcta tataatttca aagggataag cggattttat gaatcctgcc
    14521 cgattttggc aataccggtt cgcggataaa ctggcttaaa tcaaattatc ggttaaaatg
    14581 gccgtctgaa atttgtttga tgaaaacgag aaaaccatgt cccaacaata cgtctattct
    14641 atgctgcgcg tgagcaaggt tgtgccgccg cagaaaacca ttattaaaga tatttccctt
    14701 tctttcttcc ccggcgcgaa aatcggcctg ctcggtttga acggcgcggg caagtccacc
    14761 gtgctgcgga ttatggcggg cgtggataag gaatttgagg gcgaagccgt gccgatgggc
    14821 ggcatcaaaa tcggctacct gccgcaagag cctgagcttg atcctgaaaa aaccgtgcgc
    14881 gaggaagtgg aaagcggttt gggcgaagtg gcggcggcgc agaaacgctt ggaagaagtg
    14941 tatgccgagt atgccaatcc cgatgcggat tttgacgcgt tggcggaaga gcagggccgc
    15001 ttggaagcga ttatcgcggc cggttcgtcc acgggcggcg gtgcagagca tgaattggaa
    15061 atcgctgccg acgcgctgcg cctgccggaa tgggatgcca aaatcgataa tttgtccggc
    15121 ggtgaaaaac gccgcgttgc cttgtgcaaa ctcttgttga gcaagcccga tatgcttttg
    15181 ctggacgagc cgaccaacca cttggatgcg gaatcggtcg agtggctgga gcaatttctc
    15241 gtgcgcttcc ccggcacagt cgttgcggta acgcacgacc gctacttcct cgacaacgcc
    15301 gccgaatgga ttttggaact cgaccgcggc catggtattc cgtggaaagg caattactcg
    15361 tcttggctgg agcagaaaga aaaacgcttg gaaaacgagg caaaatccga agccgcgcgc
    15421 gtgaaggcga tgaagcagga attggaatgg gtgcgccaaa atgccaaagg ccgccaagcc
    15481 aagtccaaag cgcgtttggc gcgttttgag gaaatgagca actacgaata ccaaaaacgc
    15541 aatgaaacgc aggaaatctt tattcccgtt gccgagcgtt tgggtaacga agtgattgaa
    15601 tttgtaaatg tttccaaatc gttcggcgat aaagtgctga ttgacgattt gagcttcaaa
    15661 gtgcctgcgg gcgcgattgt cggcatcatc ggtccgaacg gcgcgggtaa atctacgctg
    15721 ttcaaaatga ttgcgggcaa agagcagccc gattccggtg aagtgaaaat cgggcaaacc
    15781 gtgaaaatga gcttgattga ccaaagccgc gaaggtttgc aaaacgacaa aaccgtgttc
    15841 gacaacattg ccgaaggtcg cgatatttta caggtcgggc agtttgaaat ccccgcccgc
    15901 caatatttgg gacgcttcaa tttcaaaggc agcgaccaaa gcaaaatcac ggggcagctt
    15961 tccggcggcg aacgcggacg tttgcacttg gcgaaaacct tgttgagcgg cggcaatgta
    16021 ttgctgctgg atgaaccgtc taatgacctc gatgtggaaa ccctgcgcgc gctggaagac
    16081 gcattgttgg aatttgccgg cagcgtgatg gtgatttctc acgaccgttg gttcctcgac
    16141 cgtattgcta cgcatatctt ggcttgcgaa ggcgactcca aatgggtgtt cttcgacggc
    16201 aactatcagg aatacgaagc cgataagaaa cgccgtttgg gcgaagaagg cgcgaaaccg
    16261 aaacgcatca aatacaaacc ggtaacgcgt taacctccga aacaatgccg tctgaaaggc
    16321 tttcaggcgg catttttaca aggcagcacc gtttaaaaca gcattgcaat cctcaagaca
    16381 atcaaagtca tcaccgcagc cgccatatcg tccgccataa tgcccaaacc gccgtgcaga
    16441 ttcttgtcaa accaaccgac gggagacggt ttgagcgcgt caaacagacg gaataggaca
    16501 aatgccgcca gccaccacgt ccacctgaac ggcacaaacg ccagcacaaa cagcatggcg
    16561 acaatctcgt cccaaacaat cccaccatgg tcgctgacac ccgtttcacg ttccgcataa
    16621 gcgcaaatgc gtatgcccca cataaacagc acgatacaca aaaaagccag cagcagcccg
    16681 tctatgccga gcaaaatcag cacaaatgcc aaaggcagtg ccgccaaagt gccaaatgta
    16741 cccggcgcga acggagccag cccgctgccg aaaccaaaag ccaaaaaaca caacggtcgt
    16801 ttcaacagcc acgcaaagtc aggtttaaaa tcagccaaaa tgatcgaatc ctaaagaatg
    16861 tagttccaat tccctgccgc cgtcatctaa aactttcaga cggcatcctc cgttgatttt
    16921 gccgatgcgc gttaccggca cgccgcaccg ttctgccgca tcaagcacgc ggctgcggca
    16981 actttccggc gcggtaaaca ccagctcgta atcgtcgccg cccgccaaag tataagacag
    17041 ccattgcgct cggggcaaaa tatctttcaa tacggataaa gacggcagcg aatcggccca
    17101 aatttccgcc cccacgccgg aagcggtcag gatatgcccc aaatcttgcg cgaggccgtc
    17161 tgaaacatcc tgcgccgccc gggcaaacgg caacagcgca agccccagcc caacccttgg
    17221 ctcggggcgg agcagctttt gttcgcattc ggcaaacaca tcatccggca acacacaccg
    17281 tttcagacgg cagttcaaag ccgccgccgc cataccgaca cgccccgaca cccaaatatc
    17341 gtcgcccgca accgccgcat cacgccgcaa cgccctaccc ttcggcaatt cgccgataat
    17401 ggttacattg aacgccatat cgcccttggt cgtatcgccg ccgattaacg ttacgccaaa
    17461 cttttttgcc aaaccgaaaa agctgccgca aaaccgtttc agccatacct catccaattc
    17521 gggcaacgcc gcgctcagca acacccaacg cggtatcgca cccatcgccg ccatatccga
    17581 aacattgacg gccaaaacct tccaagccaa gtcttcaggt ttgacatttg caaaaaaatg
    17641 cctgtccttc aaaagcatat ccgcactgaa acacaaatcg aagccttcac gcgggcggac
    17701 aatcgccgca tcgtcgccta tgcccaatac gacatcatta tccgtgcctg tttgcaaata
    17761 ccgtttgatg aagtcaaatt ctttcatatc ccaaaatatc cggcgggcga atccaattta
    17821 aatcatagca aggcagcaaa ggccgtacaa acaataaagc ggctcattca gtgtttcagc
    17881 gtatttcact tttagctttg gccataccgt acccgtatgc accgaccacc ctgtttcaac
    17941 acacaaacgg catatcaaag caccgcactg cacgccaccc cgaatgcaaa gcggcaactt
    18001 ccgccaccga ttaggctcaa tcgctgcaac tgacggggtt tcaaccgaaa agggctgatg
    18061 ataaaaccat atccggcata cagtgccgca cacatctggc acgattccat ccatttccca
    18121 atgaagggga aaggcgtgaa tttgtatgaa ttatcccttt cagggcttga tacagaaagg
    18181 attccctttc tatgggcaaa cccacatcct accgccttaa aatcagagtt tcaaccgata
    18241 tagtggatta aatttaaacc agtacagcgt tgccttacct tagctcaaag agaacgattc
    18301 tctaaggtgc tgaagcacca agtgaatcgg ttccgtacta tttgtactat ctgcggcttc
    18361 gtcgccttgt cctgattttt gttaatccac tataaagcac ggcaatggga cacaaacctg
    18421 aatctgaatc tgaatctgaa tccgaatccg aatccgaacc tgcaccccga ttctgacgat
    18481 agccgtttca gaaaaccacc caaaaaaaca aaccccgcaa aagcgggggt ttgtttcaca
    18541 tcatcgatgc cgaccgacgt ttcacgaata ttgcaacagt acccggtaca aaatccgcta
    18601 acctcatgca tcggcaagat attgcctagc cttagtgttg gtgatgattg tgtgccggca
    18661 caacctgacg ggttacgatg ctgcggattt tcacatccac acggcggtca ggttcgatac
    18721 atgcaatcag agcctcacgt tttttggctt tagagacttt cgcacccagt ttggcaactt
    18781 cggcttcaca aacttgagtc atttgcgctt gagattcgcc caagccgaca gcagaaattc
    18841 tagaaacagg tacgccgttg ctgaccaggt tgtttgccac tacgtatgcg cggcgttcgg
    18901 acagggcctg attgtatttg tcagaaccca taaagtcggt atggccttcg acgcggacag
    18961 attggatatt ggtttgaccc aggcgttgcg ccaatacttt caggttgtct tgagcttcgg
    19021 cgcgcaatga atccttatcg aaaccgaaca gggttttggc agacagggaa atggtttcat
    19081 caacatattg cggagcctgc tccacaacga cgacaggcgc gggtgcgggt tcgggttctg
    19141 gctcgggttc gggggcagca accgcatcgc cgcattctac gcgaccttgg cttgctttat
    19201 caaagtaggc gtttttccag cattcgccat agttgttgcg tacgatttcg ttcgactggc
    19261 cgcttacggt gtaaccctga acggacgcct cgcccgcaac agcagtgccg gaagcgagca
    19321 atgcaacgaa taatgcgctt aatttcagct gtttggtcat tttattccct cattaaattt
    19381 gtacagcaga tacagaagca actgctgaat tgccaacata caggccgctg tagaaacatg
    19441 gcggcaaatc ggatatttca gtctccacta taaagaagca gggggaggac tgtcaatact
    19501 caacgcctga aaacaaccgt aaaacagcct gtttcctgat agtctatcat gccgaaaaat
    19561 caattccgtg tcattacttt agggggattt tttccatatc gcacgattgc cgttgcacaa
    19621 aaacaacaaa cacaacggca aagccccata ccgtaccggc aagaaaatat gataaattat
    19681 aaacaatgtt cagccacccg acacagaccc acaccgaccc gccatgaaat tacaacaatt
    19741 gaaatacgcc ttagaagttt accagcacaa cctgaacgtt tccgaagcgg ccgaagcctt
    19801 gtttacttcg caacccggca tctccaaaca aatcaaattg ctggaagaag aaatcggcat
    19861 tcagattttt atccgcagcg gcaagcgcgt ggtttcggtc tcgcagccgg gcaaggtggt
    19921 tttggatatt gcggaacgta ttttacgcga tgtacagaac attaaaaata tcggcagcga
    19981 gtttaccgga caggacagcg gttcgctgac ggttgccacg acgcatactc aggcacgcta
    20041 tgccctaccc ttgattgttg ccgattttgt gaaacgctat ccgaaagtca acctgaccat
    20101 caaacagggg agccctgccg ccatcgcacg tatggttacc tcaggcgagg cggacttggc
    20161 gattgttacg gaacggatag acgaccatcc cgaactggga aaacttccct gctatgactg
    20221 gactcatgcg gttatcgtac cgaacaacca ccccttgctc gaatgcagaa accccctccg
    20281 cattgaagat ttggcgaggt ttccgctgat tacttatgaa tttgcattca atgcgggcag
    20341 cagcatcgcg cgggcatttt ccaaagcccg tttggaacag ccggatgtcg cattggcggc
    20401 ggcggatacg gacgtattga agacttatgt gcgcttgggt ttgggcgtgg gactgatggc
    20461 gaaaatggcg tacaacccgg atacggacgg cgatttgcag cttgtggatg cggcacacct
    20521 gttcgagccg tcgccgacgt ggattgcttt gcgcagcgat acttatttgc gcggatatgc
    20581 ctacgacttt atccaagcgt ttgcgccgca cctgacacgc gagaaggtgg ataggattct
    20641 gtacacgccc atcagcgagg atttttcgat ttaggcggct gccggttttc agacggcact
    20701 ttgcggcaga tacaacaaac aggacagatg ttttcgtctg ccctgtgttt attgagaatg
    20761 ctgtctgaaa tgttcgtacg ggttaatcaa atggcgtgcg agcagccgga caccattttt
    20821 ttcaacacct gcagattgag gattttgatg tgcttatgct cgacggaaat caatccttcc
    20881 tgatggaact tggataatgt gcggctgacg gtttcaagtt tcagcccgag ataactgccg
    20941 atttcttcac gagacatgcg caggatgaaa tcgttggcag caaaaccacg ggaataaagg
    21001 cgttgggaga ggttcagcag gaaggcggca atccgctctt cggcgcgcat attgcccaac
    21061 agcagcataa caccttggtc gcgcacgatt tcacggctca tcatgcggaa gaagtgcgta
    21121 cgcaggctgg ggatgttttg ccccagttct tcgatgtggg taaacggcag ttcgcacact
    21181 tcgctgtctt ccaaggcgac cgcgtcgcaa ctgtgcacat gggaacagat gccgtccatg
    21241 ccgatgagtt cgcccgacat aaagaaaccc gttacctgat cgcggccgtc ctgactggcg
    21301 acggttgttt tgaagaagcc cgaacggatg gcaaagagcg aggtaaaggc ttcgccgaca
    21361 cagaacaggt attcgccctt tttcaggcgg cggctttgac ggatgacggc atcgagttgg
    21421 ctgagctcgt tgggcagcag cccgacaggc aggcagagtt cccgcaaaga acaggaagaa
    21481 cacagcgttt tcatctgatg tgtagtatta tgcgaagcca taccgtacct ttttgtgcgc
    21541 tttgccccat catgattata gtggattaaa tttaaaccag tacggcgttg cctcgccttg
    21601 tccttattta aatttaatcc actatatgtg cttattgaca catatcaaga caggtttatc
    21661 atactgtggc attctaccaa actatccaaa atttgactaa catcataaaa ccgcacacac
    21721 accatgaaaa tcattcagat acagaacaat cacaatgtaa acgatgaccg ccccgagttt
    21781 gaccgcgcgc tgattgccag cctgcccgcc agcggcccgc gctacacttc ctaccctacc
    21841 gccgaccgtt tccatgacgg tttccgcgaa ggcgaatata tcaaagcttt acatttgcgc
    21901 ggtatgggcg cgttaaacaa accgctttcc ctttacattc acattccgtt ctgcaacacc
    21961 atctgctact actgcggctg caacaaaatc atcaccaaag acaaaagccg cgccgatgcc
    22021 tacatcgaat atcttgaaaa agaaatggaa ctgctcgctc cacatctgaa cggacggcac
    22081 cagcttgccc aactgcactt cggcggcggc acgccgacct ttttgagcga cgaacagatc
    22141 gaacgtgtct tccgcatgat acgcaaacat ttcgagttaa tccccaccgg cgaatactcc
    22201 atcgaaatcg acccgcgcaa agtcagccgc gacaccgtcc tcatgctcgg cagactcggc
    22261 ttcaaccgca tgagcatcgg cattcaggat ttcgacccca aagtgcaggc ggcggtcaac
    22321 cgcatccaaa gttacgaaga aaccaaagaa gtcatcgatg cggcgcgcga agcggggttc
    22381 aaatccgtca gcgtcgattt gatttacggc ctgccgcacc agacttcgga aagcatcaaa
    22441 accaccatcg ataccgtttt gtcgctcgat cccgaccgcc tcgcccttta tcactacgcc
    22501 cacctgccgc acgtgttcaa accgcaacgc cgcatcgata ccgcctccgt ccccgacagc
    22561 gaagagaagc tcgatatgct gcaatactgc gtccaaaccc taaccgaacg cggctacgtc
    22621 ttcatcggca tggatcattt cgccaaacct gacgacgaac tctccatcgc cctcaaagaa
    22681 ggcttcctcc agcgcaactt ccaaggctat tcgacctacg cggattgcga tttggtcgcc
    22741 atcggcgtgt cgtccatcgg caaaatcggc agcacctatt cccaaaacga acgcgacatc
    22801 gatgcctact atgccgccat cgacgaaggc agactgccca tcatgcgcgg ttatcagctc
    22861 aatcaggacg acatcctgcg ccgcaacatc attcaggatt tgatgtgccg tttcgcgctc
    22921 gactatcgga tttacgaaag tatgttcggc atcccgttcg accgctactt caaagacgaa
    22981 ctggcggatt tggaaaaact cgccggtttg ggattggtgc gcctgaacag ccacggactg
    23041 accgttaccc cgaaaggacg cttcctcatc cgcaacatcg ccatggtttt cgattaccac
    23101 ctgcgccata aagaaaccaa ggcgaaatat tcgcaaacgg tgtgattgtg gctaacgtac
    23161 aaatgccgtc tgaaaggctt tttcagacgg cattttgctg ccggcaggat aagtgttttc
    23221 aagaacaggc ggcggcatat cataacgttc cgcacctttg tgtccgaccg ttccgaaacc
    23281 aagatatagt ggattaacaa aaaccagtac agcgttgcct cgccttgctg tactatctgt
    23341 actgtctgcg gcttcgtcgc cttgtcctga tttttgttaa tcactatacc aaacggcata
    23401 tcccgacaga acagattgtg cataaggcac aagcccgcac attccatcaa caaaatgccg
    23461 tctgaacacg ggttcagacg gcatcagtat tttacaatca gaatactgcc tgtaaaacca
    23521 agtagcagac aaccgacaat acggcggcgg caggcagggt aatgacccac gccaaaccga
    23581 tgggcttcat cagtttccag ttggcattgc ggttgaccag accgatgccg agtaccgcgc
    23641 cgaccaagat atgcgtactg gacacgggca gccccatcag cgacgcgccc atcacgacgg
    23701 atgcggcgga cagttcggcg gtaaaacccg aagcaggatg catttccgcc aaactcgtac
    23761 cgacggtttt aatcacctct ttaccgacaa accacaaacc gacaatcagc gcgataccga
    23821 aagtcagcat cgcaatcggg gggacgacat tttgcgcggc aacgctgttg gtacgcaaaa
    23881 catccataat cgcggcaaac ggaccgatgg cgttggcgat atcgttcgca ccgtggctga
    23941 atgcgaagcc gcaggcggta aagacctgca tccatgaaaa catctgaaag gtcgatttgc
    24001 ccaagtcttt acgcttgagg cttttggcaa acacaaacgt ccccatccac accgccgcgc
    24061 ctatcataaa gatggtcagg aagctgttga cgttgctcat ccccaaatgc aggtttttca
    24121 agcccttgaa aatcagcata gcggaaatca tcatcgcgcc gaacgaagcg ataaagggaa
    24181 tccaagaatg cagtgccttg taggaatcga cattgttttt acggttgtcg aacgcataaa
    24241 gaccgcggta atactccgat tgcagctctt gcggatcgaa ttcgggttcg tcgtaaattt
    24301 gcgcgtcgtg cgccattttg gtggcgtact cgactttttc ggcttcggac aaaccctcga
    24361 aaaacaggcg gtgccgttct ttataggcct ttttttcctg cttgatgccc ttgagcgtgc
    24421 cttccgccca agcgttgtaa tctaagacgt ttttcttgac gcgcgaaaac aggaaatagg
    24481 acaccgcgcc gcccaacacg ggcgacaata cccaagaaac accaataccg cccagcttgc
    24541 cccaacgtat caaatcgccc gatgcggcat cgttcattac cgccatacat accgcgctac
    24601 cgacaatgcc gccgataatg gaatgggtgg tagataccgg aagccctttt ttcgaggcaa
    24661 acaacagcca caacgccgcc gccaaaagcg cggacatcat aataaacaca aactgtatgg
    24721 gttcgaaatc aacacccttc aaatcgacga tgcctttgcg tatggtattg gttacctcgc
    24781 cgcccgcgat gaccgcgccg ctgacctcaa ataccgccgc aatcagcaaa gcctgcggga
    24841 tggtcagcgt acccgcaccg acgctggtgc cgaaagaatt ggcaacatcg ttgccgccga
    24901 tgttgaacgc cataaacacg ccgaacatcg tggcaataat gaataaggcg gcgtaattgt
    24961 aatgggtata acccaagccc caataaataa aatagccgac tgtacctacc agcatggcgg
    25021 caaagacggc gttgatggtt ttaacatttg cgctcatttg gatttgagcc atggcaatct
    25081 tcctttaatg tggtggaaat catgagtgtt gccgacactg tactgctgcc tccggtcgaa
    25141 ctgccgtttc gggatatggc agacgcatcc ttccttctga accgcatccg aataccccca
    25201 aacctgaccg aatgcaaaac tgctgccgga aacggtttgt atgacacttc tactactgga
    25261 tgttgcgggc gcattataat atttttccat ccgtcttgaa acatttattt acactttatt
    25321 tacactgcgg cggcaaatcg gtatacgagc gtcaatacac gttaaaatgg cgttttgcac
    25381 cagtttggga gtgatgatgg aaacacagct ttacatcggc atcatgtcgg gaaccagcat
    25441 ggacggggcg gatgccgtac tgatacggat ggacggcggc aaatggctgg gcgcggaagg
    25501 gcacgccttt accccctatc ccgacaggct gcgccgccaa ttgctggatt tgcaggacac
    25561 aggcgcagac gaactgcacc gcagcaggat tttgtcgcaa gaactcagcc gcctgtacgc
    25621 gcaaaccgcc gccgaactgc tgtgcagtca aaacctcgcg ccgtccgaca ttaccgccct
    25681 cggctgccac gggcaaaccg tccgacacgc gccggaacac ggttacagca tacagcttgc
    25741 cgatttgccg ctgctggcgg aacggactca gatttttacc gtcggcgact tccgcagccg
    25801 cgaccttgcg gccggcggac aaggtgcgcc gctcgtcccc gcctttcaca aagccctgtt
    25861 ccgcgatgac aaagaaacac gcgtggtact gaacatcggc gggattgcca acatcagcgt
    25921 actcccctcc gacgcacccg ccttcggctt cgacacaggg ccgggcaata tgctgatgga
    25981 cgcgtggatg caggcacact ggcagcttcc ttacgacaaa aacggtgcaa aggcggcaca
    26041 aggcaacata ttgccgcaac tgctcgacag gctgctcgcc cacccgtatt tcgcacaacc
    26101 ccaccctaaa agcacggggc gcgaactgtt tgccctaaat tggctcgaaa cctaccttgg
    26161 cggcggcgaa aaccgatacg acgtattgcg gacgctttcc cgttttaccg cgcaaaccgt
    26221 tttcgacgcc gtctcacacg cagcggcaga tgcccgtcaa atgtacattt gcggcggcgg
    26281 catccgcaat cctgttttaa tggcggattt ggcggaatat ttcggcacac gcgtttccct
    26341 gcacagcacc gccgaactga agctcgatcc gcaatgggtg gaagcagccg catttgcgtg
    26401 gttggcggcg tgttggatta atcgcatccc cggtagtccg cacaaagcaa ccggcgcatc
    26461 caaaccgtgt attctgggcg cgggatatta ttattgagcg caaataccgt ctgaaagcca
    26521 tttccgccgc tcagacggca ttttcgcccc tttcgtttac aaacccttaa aatccattta
    26581 cactcaaacc cgttcaaaac aaaacaaacc ctgccatgaa aatcctgctc ctcctcatcc
    26641 ccctcgtcct aaccgcctgc ggcacactga ccggcatacc cgcccacggc ggcggcaaac
    26701 gctttgccgt cgaacaagaa ctcgtcgccg catcgtcccg cgccgccgtc aaagaaatgg
    26761 atttgtccgc cctgaaagga cgcaaagccg ccctttacgt ctccgttatg ggcgaccaag
    26821 gttcgggcaa cataagcggc ggacgctact ctatcgacgc actgatacgc ggtggctacc
    26881 acaacaaccc cgaaagtgcc acccgataca gctaccccgc ctacgacact accgccacca
    26941 ccaaatccga cgcgctctcc agcgtaacca cttccacatc gctcttaaac gcccccgccg
    27001 ccgccctgac tagaaacagc ggacgcaaag gcgaacgctc cgccggactg tccgtcaacg
    27061 gcatgggcga ctaccgcaac gaaaccctgc tcgccaaccc ccgcgacgtt tccttcctga
    27121 ccaacctcat ccaaaccgtc ttctacctgc gcggcatcga agtcgtaccg cccgaatacg
    27181 ccgacaccga cgtattcgta accgtcgacg tattcggcac cgtccgcagc cgtaccgaac
    27241 tgcacctcta caacgccgaa acccttaaag cccaaaccaa gctcgaatat ttcgccgtcg
    27301 accgcgacag ccggaaactg ctgattgccc ctaaaaccgc cgcctacgaa tcccaatacc
    27361 aagaacaata cgccctctgg atgggacctt acagcgtcgg caaaaccgtc aaagcctcag
    27421 accgcctgat ggtcgatttc tccgacatca ccccctacgg cgacacaacc gcccaaaacc
    27481 gtcccgactt caaacaaaac aacggtaaaa accccgatgt cggcaacgaa gtcatccgcc
    27541 gccgcaaagg aggataaacc gtgaaaccgc tgcgcagact gacaaacctc cttgccgcct
    27601 gcgccgtagc ggcggccgca ctcatacagc ccgccctcgc ggcggacttg gcgcaagatc
    27661 cgttcattac cgataacgcc caacggcagc actacgaacc cggcggcaaa taccacctct
    27721 tcggcgaccc gcgcggcagc gtctccgacc gcaccggtca aatcaacgtc atccaagact
    27781 atacccacca gatgggcaac ctgctcatcc aacaggcaaa catcaacggc acaatcggct
    27841 accacacccg cttttccgga cacggacacg aagaacacgc ccccttcgac aaccacgccg
    27901 ccgacagcgc aagcaaagaa caaggcaacg ttgacgacgg ctttaccgta taccggctca
    27961 actgggaagg acacgaacat catcccgccg atgcctacga cgggcccaaa ggcagcgact
    28021 atcccgaccc cacgggcgca agggacgaat acacctatca cgtcaacggc acagcacgca
    28081 gcatcaaact caatccgacc gacacccgca gcatccggca acgcatatcc gacaactaca
    28141 acaacctcgg cagcaatttc tccgaccgcg ccgatgaagc caacagaaaa atgttcgagc
    28201 acaatgccaa gctcgaccgc tggggcaaca gcatggagtt tatcaacggc gtcgccgccg
    28261 gcgcgcttaa cccctttatc agcgcgggcg aagccgttga ccagtggatg caggaaaacc
    28321 ccaatgccgc cgaaaccgtc gaagccctgg tcaacgtcct gccgtttgcc aaagtcaaaa
    28381 acctgacaaa ggcggcaaaa ccggggaagg ctgcggttag tggggatttc tcagactcct
    28441 acaagcataa cactgcttca agattatctc agtctgtaga tggagaaatg tttcaaaccc
    28501 gcaatgttga ttttaaagca aaatctattg ggactaaaat tcatgatgga gctcaaggga
    28561 aacatatttc aggacataga aactacattg aaggtaagag tactttaaat caaaacatta
    28621 atcctcaaga attgttgaac ggaatacatt caggtgctta tccagttatt tctaaaggag
    28681 caagaggaaa tcctgttgtt gattttgggt atcctatagg cagcgatggg aaatcaggat
    28741 taagtaccaa ttttggtacg attcattcag gtaaaaatgg agttcacatt gttccggcta
    28801 accctaaaac cattaaaaag gtgcaatagt tatgaatata ttaccaagct ggctgcgagt
    28861 cggtatgaat atagcaatgc tgggcatgat acactcagat atcaggttaa ttaccgtaga
    28921 ttacgaggaa ggaagaaggt ttttaaaaat caaaaattat ttatcaagag aagccatcac
    28981 agaagaccat gaagatatgg aatatttgat tacagagtta tggtctatgt gtggagaata
    29041 ttttgatgaa gctgactttg aatgtattta ttctaatcat tcttctatgg agttaaacca
    29101 aataaatggt gcagtattca ggagaaagga attaatttcg caagcgtagg ttaaaaaacc
    29161 aacaatcaca atgtcttctg aaaccgtgtt taattttcag acggcatttc cttcatttga
    29221 aataggatat tgagaactga gttcttcaaa aatcctacac ctgctccttc cacggcagca
    29281 ccttggtcaa aacggcagac ggctacaaag ccattgcccg tatccgaacc ggcgaccgcg
    29341 tcttctccaa ggacgaggca agcggaaaaa cgggatacaa acccgttacc gcccgatacg
    29401 gcaatccgta tcaagaaacc gtttacatta aagtttcaga cggcatcggc aacagccaaa
    29461 ccctgatttc caaccgcatc catccgtttt attcgggcgg caaatggatt aaagcggaag
    29521 atttgaaagc gggaagcagg ctgttatccg aaagtggcaa aacccaaacc gtccgcaaca
    29581 tcgttgtcaa accaacaccg ctcaaagcct acaatctgac cgttgccgac tggcatactt
    29641 acttcgtcaa gggcagtcag gcggaaacgg aaggggtttg ggttcataat tcttgtccgc
    29701 ctaaaagaac aggaagctcc aagaatgaaa aacatggaga cggcggtcga agtcaaatat
    29761 cagcggaatc aagaattgct gaattaaaaa ataaaattat tcccggaatg cccaaaaatg
    29821 aacgcttaaa gattgagaaa acaatcaaaa atattacaaa aaatgccaat cgaaaagcaa
    29881 aaggagaaga gcatggtcga cgcggtcgtt aaaactcccg aatttttacc ttttacttct
    29941 gtaggaatat tccgttttgg tgcggatata acacagtaca aaaacatact gggaactttt
    30001 atgtatgaac ctcctgatga gtttagaaca gaatattatg aatctcccga ctcaaattta
    30061 ctaattgccg tcaagaaaaa caaaattatt tcgatatttt gttatcagga gctatatttt
    30121 atgggcgtta atataatagg tctgaatttt gaagatttta aacagctttt ccatcaccct
    30181 aaatcatacg gtgttgataa atattattta tcaaatgaat cttatccgac atatgtctat
    30241 gagtttgatg aaataggagt acaagcttgg gaagcaaaag ggaaaattgt tactatcatt
    30301 gccgggggca aagacaatta ttcgacagaa ccttactacg atgaataaca ttaatggcag
    30361 gcataggttg ggttgagaac tcaacaacaa aaggtcgtct gaaaccgtaa tcgatttttc
    30421 agacgacctt tctgtcaatc caaacagatt gtcgaatctt aatccaacct gtgcttgctg
    30481 tacggaacag gcacggtgtt cattcacaag ttaagtcata tattgaatca aaaggcggca
    30541 ttgttaaaac aggtttagga gattaaacat ggcatcatat gtttccataa aaggatggat
    30601 tgaatgctct gacgatgata taaaaatcat ccaagaaaac attaataatt tttggaataa
    30661 ttgtcccttc aatatcgaag agaaagaatc tgcaaaaata tataaaagcg ggtgggtttt
    30721 cccgacaaat agttttaatt ggagcagcta tatttttttt ggtgcatgcg taaaatctta
    30781 tttcattatt tattttgaaa aatgcattaa aacaataatg gaattggata ttgaaatatc
    30841 aggttttttt gaattagatt attatgaaga tagttataaa gtacattgga aaataaataa
    30901 tggaaatttg atacaaacga ctaattaaat ggacaaatat aagttagatt ggacacccaa
    30961 acctaaaaac tgtctgaaac tcaatttggt tttcagtaag cgtaggttgg cttaaaaacc
    31021 caaccaccaa aatgccgtct gaagcggtat tcagctttca gacggcattt tgatgaatga
    31081 aacaggatat tgagaactaa gttctttaaa aatcctacac ctgctccttc cacggcagca
    31141 ccttggtcaa aacggcagac ggctacaaag ccattgcccg tatccgagtc ggcgaccgcg
    31201 tctttgccaa ggacgaggca agcggaaaaa caggatacaa acccgttacc acccgatacg
    31261 gcaatccgta ccaggaaacc gtttacattg aaatttcaga cggcatcggc aacaaccaaa
    31321 ccctgatttc caacagcatc catccgtttt acagtcaagg aaaatggata caggcaggtc
    31381 gtctgaaaaa aggcgacacc ctgctttccg aaagcggtgc aaaacagacg gttcaaaaca
    31441 ttaccctcaa acagcagccg ctcaaagcct acaatctgac cgttgccgat tggcatactt
    31501 acttcgtcaa gggtgatagg gcggaaacgg aaggggtttg ggttcataat gattgtccgt
    31561 atggtagttc tagcgcaaaa ggtaaaagtg gcagtgagag aaatactgct aaacgtggaa
    31621 ccttcagaca agaaacgcta aaaaatgcat gggatttggc agcagatggt agccagccta
    31681 attcaaaaaa atgtcctaca tgtggtaaag atgtatatgg taatccccat aacaaggaga
    31741 aacgtaatac aaaagatggt tgggatggaa gtcataatcc atcatggagt aaccgtcaac
    31801 atagttctga tcgtaaggag caactaaatg attataataa aggagtaagt ttagaatgca
    31861 gacattgcaa tcgatctggt ggcaacaagg atgaaaggtt taagaaaaaa tgattacagt
    31921 cgaacattta gagcattatt tgggtgaaat cgaaagcggt ataaaatgct tggatcgacg
    31981 ttatcatctc agcgtttccg tcttcccatc acaaccatat aaaggggtaa ctactttttc
    32041 tactttaggc ttgaatcgat atgacttgaa ctataaaagt aggtttgaat taatttttac
    32101 ctgttctgaa gaatggaata aagaaaatat tgcagctttt ctatcaggag tggctgaata
    32161 tttgattgac aatagacaac ctattttaag aggtgaaatt attcaattac ccagggtaat
    32221 tatcgaaggt agcaaaatgg atgcactgta tgtttccgcc ccattttatt tcgatgatga
    32281 ttttcaggtc tgttatggcg gacactacaa tactgttttt cctttgcttg tcccgttgta
    32341 taaacaggaa gcagaattgg tggaaaaaaa gggttggaat gcttttgagc agttcttgct
    32401 ggatagtgaa gttggcaacc tttcggatat gaatcggaaa ccgtttgttt ggtaagggct
    32461 ttcttaaatt tgattaaagg tcgtctgaaa ccgtgtttaa ctttcagaca acctttcctt
    32521 catttgaaac aggatattgg gaactaagtt cttcaaaaat cctgtctccg tcccttatac
    32581 gtcggtgctt tagtcaaaac ggcagacggc tacaaagcca ttgcccatat tcaagccgga
    32641 gaccgcgtcc tttccaagga cgaggcaagc ggagaaacgg gatacaaacc cgttaccacc
    32701 cgatacggta atccgtatcg ggaaaccgtt tacattaaag tttcagacgg catcggcaac
    32761 agccaaaccc tgatttccaa ccgcatccat ccgttttaca gtcaaggaaa atggatacag
    32821 gcaggtcgtc tgaaaaaagg cgacaccctg ctttccgaaa gcggcgcaaa acagacggtt
    32881 caaaacatta ccttcaaaca gcagccgctc aaagcctaca atctgaccgt tgccgactgg
    32941 catacttact ttgtcaaagg cgataaggcg gaaacggaag gggtttgggt tcataatgat
    33001 tgtccgtatg gaaatttatc ggataataaa tctgttggcg aaggaaaaaa atttacacca
    33061 gctcaaaaga aagcaatcat ccaagaaaac atgaatagaa acggaggggt agtgaagtct
    33121 gaccaatctg gagaagtttt ggttcgtcct aaaaagagcc aaaaaggtat caccccccca
    33181 tcaaatgaat ggcagattga ccatgtgcaa gcaaaaagta aaggaggttc aaatagttat
    33241 aaaaatgcac aggttttatc cagaagagaa aatattaaga aatcaaataa ataggtatca
    33301 atatgcaatg gaaatttgaa gatcctcaaa atactgccgt tattaccacc agaagaattt
    33361 tgtctaaaaa aacggaatct tagaagtatg gcatgatgct gatgatggaa tgtggcaatt
    33421 cttagatggc aatgaaattc atgaaggaga tgctgtgata gttagtttaa aagaaattgt
    33481 cactattgat tcctcagtca atctcttaag taatttacct cttggtggtt acgcttggag
    33541 aaatactata tcggaaaaat ggaatgttga ttagcaagcg taggttaggt taaaaaacca
    33601 acaatcaaag gtcgtctgaa accgtgttta gtttttcaaa cgacctttcc ttcaattaac
    33661 atagaatgtt gggtctcgac ccaacctaca cgcttactaa tctcaaatat aaccttatga
    33721 aataatgagt atttaaaaga tggaaacatt agacgaacga ataaaaaatt taggaaaatc
    33781 tcttgaagat agaattgacg ctaatctaat tgatgccaca ctagagtaca ttactttttc
    33841 agaacgtttg ctagcttttg aaacgctatg tgattatatt gaagatttca atatccagct
    33901 tacggaaaaa gaatcccaag aaatctcttt tattaataag gaatttggaa ttgaaagtac
    33961 atcagattaa taaatattag gtcggtttaa aaacccaaca atcaaaaagt cgtctgaaac
    34021 tgcttttaat tttcagacga cctatttcct tcatttgaaa taggatattg agaactaagt
    34081 tcttcaaaaa tcctacactt gctccttcca cggcagcacc ttggtcaaaa cggcagacgg
    34141 ctgaaaagca aacaccgtcc gtcgtgttgc cgtttgcgga tgagtacggg tcaaccccaa
    34201 tgccgccgaa accgtcgaag ccgccttcaa cattgccgcc gccaaagccg cgaagttggc
    34261 aaaaacggta aaaccgggga gataaaagcc gatggcagga aagtaaatgt gaggatagac
    34321 agtacggagg cagacctgct ttatccggca gggcaataag aaaacaaaaa tcagatatgg
    34381 aaaacgatag tgaagattaa accattacaa ttttctaaca ataatcacag attttacgta
    34441 gacaaaattt gtgttaccga acaagatgtg aacattttgg catccgaccg aaattatgaa
    34501 ttaaatattg aaatatttat tgacaatata attcattttc aaataacaga tgaatcttat
    34561 aaagtaaaat tttcagaata tttatttgaa aataaagaaa aaaatgattg ggatagaaat
    34621 cctgctataa attatttttt cgagataata gatgacagtt atatggactg gttgaaagaa
    34681 gaaagttttg atttttttga aaagaaatat tataaggctt atattttctt ttttagcgat
    34741 tctgtaatag aagttatcag ctcgacagaa cctgtatttt attcaaaata acaaattatc
    34801 aaacaaagct ctgattaaaa acccaacaat caaaatgccg tctgaagcgg tattcggctt
    34861 tcagacggca ttttctccga ttggcacaga atgcaggggc ttgccggctt gattttgccg
    34921 aagttgttgg cacgcaattt ggaagaggca gcaatttatg gaaaatagat ttgcaaaaat
    34981 cgttaaggat atttttagtt ttacccaatt tgtttccgaa gcggaaaata aaattcctaa
    35041 ccaatcctct cgttattacg attgctggtg ggaattggaa atcttgaatg cttccgcatt
    35101 ggaagattgg gaaatatcgg gaaagcctga aaaatgggag aaatggacag aaaaatatca
    35161 gaccgaagcg ttacagtcag tcaagcatct atttgccgaa gaagttcctg aaaataatat
    35221 agtttgcgat atttctcatt ttttgcattt tgccgattgg gcagaagccg acattcccaa
    35281 tcaatcacgt ttatatgccg aatattggtg ggaaatggaa atgttcaaaa tgtcggtttt
    35341 agaagattgg gaacactcgg gaaaaccgtt agattggaaa aaatggcaaa ggcaatatcg
    35401 atctgaagca tttgaattag ttaaaaaatt gaaccgaagc aaacaagagt aacaagccgc
    35461 agcctgcata agggttttta aagtacggca gcaaccgtag attaaattaa aaatcaaaca
    35521 atcaaagctc gtctgatata atcgatatat tctgttaaac gaaaaataaa tatgtttaaa
    35581 aaattcaaac cggtactgtt gtcatttttt gcacttgtat ttgccttttg gctgggaacg
    35641 ggtattgcct atgagattaa tccgcgttgg tttttgagcg atacggcaac tgaaatacct
    35701 gaaaatccga atgcttttgt ggcgaaactt gcccgcctgt tccgaaatgc cgacagggcg
    35761 gttgtcatcg tgaaggaatc gatgaggacg gaggaaagtc ttgccggagc tgtggatgac
    35821 ggtccgttgc agtcggagaa ggattatctc gcgctcgcta tccggctcag tcgtttgaaa
    35881 gaaaaggcga aatggtttca cgtaacggag caggaacatg ggaaagaggt ttggctggat
    35941 taccatatcg gcgagggcgg tttggttgcg gtttcgcttt cgcaacgctc gccggaagcg
    36001 tttgttaatg ccgaatatct gtatcggaac gatcgtccgt tttctgtaaa tgtgtacggc
    36061 ggaacggctc acggagaaaa ttatgaaacg acaggagaat atcgggttgt ttggcaaccg
    36121 gacggttcgg tatttgatgc gtcggggcgc gggaaaatcg gggaagatgt ttatgagcat
    36181 tgcctcgggt gttatcagat ggcccaggta tatttggcga aataccggga tgtcgcgaat
    36241 gatgagcaga aggtttggga cttccgcgaa gagagcaacc ggattgcatc ggactcgcgc
    36301 gattctgtgt tttatcagaa tatgcgggaa ttgatgcccc gggggatgaa ggcgaacagt
    36361 cttgtggtcg gctatgatgc ggacggtctg ccgcaaaaag tctattggag tttcgacaat
    36421 ggaaaaaaac gccagagttt cgaatattat ttgaaaaacg gaaatctttt tattgcacaa
    36481 tcttcgacgg tagcattgaa agcggatggc gtaacagcgg atatgcagac ctatcatgcg
    36541 caacagacgt ggtatttgga tggcgggcgg attgtccgcg aagagaaaca gggagacaga
    36601 ctgcctgatt ttcctttgaa cttggaagat ttggacaaag aagtgcgccg ttatgcggag
    36661 gctgcggcga gacgttcggg cggcaggcgc gacctttctc actgaacgca aatgccgtct
    36721 gaaaccggtt ttcagacggc attggagagt caaacgcttt ttgcaatacc gtatatgccg
    36781 aatccgattc gctacaaatt gaaaaccaca atccaaaaaa cggaaataca cattaaacgg
    36841 gcctttttac cgaccgtatc atcccatagg ttttccacac cttttttcat ccataaattc
    36901 aaaccattta agtttgcatc cttaccgaca attgcagcag catcatccgc ataacggtca
    36961 cccaaattag ccaaataacg ccaaccgcca taggtatcgc cacggaaagc ataaccacgc
    37021 aaggtttgga tttgttctgg tgttaaaaca acttcaccct cattcataat aagatccttt
    37081 aaattatttt ttacttggat tgtttacaaa actctgtacc aattgctcta cttgttggtg
    37141 ataacctacc aactcctgct gtgtgagctg ctgcttttcc cgaataaacg ggtaataccg
    37201 taccgtgaaa ccgttaatac aggaacctac gctagtgctg taatcgttct ctccatacct
    37261 atgatagttc cgatgagtaa taatcgccgg attttctcct tttttaatat agtaaaattc
    37321 atgaaaatat ggattttcag gaatatgtct tttatcttca taagcttcat attcaggata
    37381 ggcagatggc atttttttaa ccccgtaagt aagcaatctt tctcccatag tcgtgcttaa
    37441 actacacgca tcttttcgga taacaatatc gtccacgcta tccaaaccgt cgcgtagaaa
    37501 ttggataaag tgtgctttgt tttgctggtt gtatggctca agaacccagc cttggtcggt
    37561 ttttttgtaa tagacgctaa tctctatcaa attaatggag taagcatcct gcccgggcgt
    37621 gtcggaaagc cattttgtgg cattgtcttg cgtataccgt gcaagatagc cataagggat
    37681 aaccattttg gtgccctgaa aatcaaatgt aaccgtatgt tcaaatcctg tcattggctc
    37741 gggattgttg aaactggttt gttcattaac aggttcacat gaggtcatag taaaaacact
    37801 cccaataaac aaaataaaaa gttgataaat ggtagtagca tatggtctca taatttcaag
    37861 cctagaaatt agttaaagaa tatattatgg tagatactaa ctctttaagt tgacatattg
    37921 tgcgatgtcg agggctgtac catattttcc catcgtattt tcccgttctt tatatgagcg
    37981 gcaggcatcc tcataaaaga agggataccg atacggaaaa ataccccggc ataaaaaata
    38041 tactgattaa tcaatacaaa tccaacaaac agttcatcgt attcttttct gttggcgtat
    38101 aaaaaatact gatatatgcc ttcactttca tagggcgacg ctttatgtac cgtcctgtgt
    38161 gttgaaacgt cggttttcct taccgcctgc cccgcttttc cctgattgct gccaactgcc
    38221 gtccgaacct gaaccgtcag gtttcagacg gcattttttc cgcctgttcc cacaatttcc
    38281 gtttttgtgc ggcggtcagt tttttgacgg cgatttcctg tttgagcgcc gtgcctttat
    38341 ccatcccgcc tgcaacgata cgcatcgcca ccggtttgaa tacgcgggta tatttcgcgc
    38401 ctttaccggt tgtgtgggcg gcaagccgct gttgcggatt cgggctgatg ccgcaataga
    38461 acgcgctgtt ttcacacaat atcaggtaaa cgctccagtt tgacgcgttc atctgcctgc
    38521 atcctgagtt ttttccccgt tccaaggcgc aactttcagc agcagcagca tacccggcag
    38581 ggcaagtatg aaacacagct ggaaaaacgg tacataaccg agccattcga tcagataacc
    38641 ggcaaaggaa ttgatgaccg tgcgcgggac ggcggacagg ctggtaaaca gcgcaagctg
    38701 cgttgcggta aatgcgggat tggtttcacg cgccatatac gatacgaacg ccgccgtccc
    38761 caaccccacg ccgaccgctt ccgcgccgat aactgccgcc agcatcagcc tctcgcctgt
    38821 gccgaccgtg tcgaaaggtc cgaaccctgc cagccataca aaccccaaaa cggttacagc
    38881 ctgcaccgcg ccgaatagcc acaaggcttt gtttacgccg attttcagca tccacacgcc
    38941 gcccaagata cctgccgcca ctgccggcca cagtcctgca ttttttgcaa tcaaaccgat
    39001 gtctgtctta ctgaaaccca tatccagata aaacggcgtt gccaacgcgg ttgccatact
    39061 gtcgccgagt ttgtaaagga agataaacag cagcacgcac accgccgaag cgatgccctt
    39121 gcgcgtaaaa aattctttaa acggctctac cacggtctgc ttcaacgttt taggaacggc
    39181 aggcggcaac acgggttcgc gcgcaagaaa cagcgtcatc agaagaccgg gcagcataaa
    39241 cagcgaagtg atgacaaaca cctccggcca cggcatcctg tctgccagca ccaaactcaa
    39301 tgaaccggga atcagggcgg caacccgata ggcgttcaca tgaaccgagt tgcccaaacc
    39361 caattcctca tccgacaaaa tctcgcgcct gaacgcatcc aatacaatgt cctgactggc
    39421 ggaaaaaaaa gcgacaagca ccgacaagcc ggcaatcagc ggcagatgat tacgagggtt
    39481 taaaaaggca taagccgcca aagccgccag caaacctgcc tgcgtcagca gcatccaccc
    39541 gcgccgccgc cccaaaacgg gcagcctgac cgcgtccatc agcggcgacc acaaaaattt
    39601 ccaagtaaac ggcagaccga ttaacgccat cagcccgatg ctcttcaaat ccacctgctc
    39661 gctgcgtaac cacgccggaa tcaggttaat cagaaagtac agcggcagcc ccgaggcaaa
    39721 ccccgtaaaa atacagacaa gcatattgcg ggaaaagatt tgcccgataa aacctgattt
    39781 cgatgcagtc atcgttcgtg cagcccaaaa aaaacaaaag cctattgtag caaatatcgc
    39841 ccgcctgctg aaaaacgccg ccccgcgccg ccggtttgcc gttcaaatgc aaaatgccgt
    39901 ctgaaactgt gttcagacgg cattgctttt ctgaaaacca gacgtgctta caggctgtaa
    39961 tacatttcaa attccagcgg gtgcggcgcc atgcggatgc ggcgtacgtc ttcttctttg
    40021 aaagcgatgt agctgtcgat ccagtctttg ctgaacacgc cgccgcgcag gaggaattcg
    40081 tggtcggctt tgagggcggc cagtgcttct tccaaagaag cgcaaacggt cggcaccaat
    40141 gcatcttctt ccggcggcag atcgtacagg tttttatcgg cagggtcgcc cggatggatt
    40201 ttgttttgaa tgccgtccaa acccgccatc aacagggcgg caaatgccaa atacgggttg
    40261 gcggtcggat cggggaaacg cgcttcgatg cggcgcgcct tgctgctgtt cacggacgga
    40321 atgcggatgg aagcggaacg gtttttggcg gagtatgcca gtttggtcgg cgcttcaaag
    40381 tgcggcacga ggcgtttgta ggagttggtg gacggattgg taatcgcgtt caaggctttg
    40441 gcgtgtttga tgatgccgcc gatgtagtag agcgcggtgt cgctcaagcc ggcatagccg
    40501 tcgcctgcga acaggttttg accgtctttc caaatggatt ggtgaacgtg cataccgctg
    40561 ccgttgtcgc ccataatggg tttgggcatg aaagtggcgg ttttgccgaa gttgtgggca
    40621 acgttttgaa tcacatattt catgtcttgg gtttggtcgg cgcgtttgac caaagtagca
    40681 aagcgcgtgc cgatttccat ttggctgccg gtgccgactt cgctgtggtg cacttccact
    40741 tcaataccga gttcttccaa aatgtttacc atcgccgaac gcaaatcctg accgcagtca
    40801 atcggtgcaa caggtgcgta accgcctttg acggtcgggc ggtggccggt gttttgaccg
    40861 tccatatgca gaccgcttgc ccacgcgccg ctttcggacg tgatttcgta acgggttttg
    40921 tgcatatcgg tttcaaattc tatgccgtcg aatacgaaaa actcgggttc gggaccgaaa
    40981 taggcggtct cgccgatacc ggaagatttc aaataggctt cggctcggcg ggcgatggag
    41041 cgcgggtcgc ggtcgtaacc ctgaccgtcg gcgggatcga taacgtcgca agtcaacaca
    41101 acagtcgcat catcataaaa aggatcgacg aaggctgtag acgcatcggg acgcaactgc
    41161 atatcggaag cctgaatgcc tttccagccg ccgatagacg aaccgtcaaa cgcctgaccg
    41221 ttttcgaacc actcttcggg gtcttccaac acgatgcgcg caggcacggt aaagtggtgc
    41281 tgcttgcctt tggtatcggt aaagcgcaaa tcgacaaagc gggcttcgct ttcttcaatc
    41341 aattttacgg cgtttttaat agacattttt cagctcctgg aaaagggaaa tagcaaaata
    41401 tacggaacgc ggcagattag cccaaagcca gcatgattct accacgtcca tgccgtctga
    41461 aactcgccct gcgtcaaatt tcaagctgga aaatatagtt tcagacggca agattgtcaa
    41521 caatatgctt cggtttgtct gttcaaaagc agaatacccg cccttttgtc cgaatgccga
    41581 caaaacagat gccgcctgaa aacagtttag acggcatcgt tcccatcttc gcgccgccgt
    41641 tataaaatga ccgccccgcc ttgatggaat atgactatgc acgccctccc ccgctacgcc
    41701 gtttttggca accccgtcgc ccacagcaag tcgccgcaga ttcatcaaca atttgccctt
    41761 caggaaggcg ttgacattga atacgaacgc atttgcgccg acatcggcgg tttcgcgcag
    41821 gcggtttcga cattttttga aacaggcggt tgcggggcaa acgttaccgt accgttcaag
    41881 caggaagcgt ttcatctggc ggacgagcat tctgaacgcg cattggctgc cggcgcggtc
    41941 aacacgctga tttttctgaa aaacggaaaa ctgcgcggcg acaataccga cggtatcggt
    42001 ttggccaacg acatcacgca ggtcaaaaac attgccatcg aaggcaaaac catcttgctt
    42061 ttgggcgcgg gcggcgcggt gcgcggcgtg attcctgttt tgaaagaaca ccgtcctgcc
    42121 cgtatcgtca ttgccaaccg cacccacgcc aaagccgaag aattggcgcg gcttttcggc
    42181 attgaagccg tcccgatggc ggatgtgaac ggcggttttg atatcatcat caacggcacg
    42241 tccggcggct tgagcggtca gcttcctgcc gtcagccgtg aaatttttcg caactgccgc
    42301 cttgcctacg atatggttta cggcgacgcg gcgcaggcgt ttttgaactt tgcccaaagc
    42361 aacggcgcgg ccgaagtttc agacggcctg ggcatgctgg tcggtcaggc tgccgcctcc
    42421 taccatattt ggcgcgggtt tacgcctgat atccgcccca ttatcgaata catgaaagcc
    42481 ctgtaaccat gttccgcatc atcaaatggc tgattgccct gcccgtcggc atctttatct
    42541 ttttcaatgc ctatgtgtac ggcaacatca ttacctaccg cgccgtcgcg ccccatcaga
    42601 ctgcctttat gtcgatgcgg atgaagcagt ttgaacagga aggtcgcgat gtcgcactgg
    42661 attaccgctg gatgccctac aaccgcatct cggtcaacct gaaaaaagcc ctgattgctt
    42721 ccgaagatgc ccgtttcgcc gggcacggcg gcttcgattg gggcggcatt caaaacgcca
    42781 tcaggcgcaa ccggaacagc ggcaaagtga aggcgggcgg ctcgaccatc agccagcagc
    42841 ttgccaaaaa cctcttcctc aacgaaagcc gcagctatat ccgcaaaggc gaagaagcgg
    42901 cgattaccgc gatgatggaa gccgttaccg acaaagacag gatttttgaa ctgtatttaa
    42961 actcaatcga atggcactac ggcgttttcg gcgcggaagc cgcgtcccgg tatttttatc
    43021 aaatacccgc cgccaagctg accaaacagc aggcggcaaa actgacggcg tgcgtccccg
    43081 ccccgctcta ctacgccgac catccgaaaa gcaaacggct ccgcaacaaa accaatatcg
    43141 tgctcagacg catgggttcg gcagagttgc ctgaaagcga cacggactga ttgtttcaga
    43201 tatggaaatg ccgtctgaac tgcggttcgg acggcatatg ttttctggtt tttatagtgg
    43261 attaacaaaa atcaggacaa ggcgacgaag ccgcagacag tacaaatagc acggaatcga
    43321 ttcacttggt gcttcagcac cttagagaat cgttctcttt gagctaaggc gagccaacgc
    43381 tgtaccggtt taaatttaat ccactatacc tgcccgacag ccgcaaagac cgtatcatac
    43441 atagcaggca ttgcggtgcg ggattactgc cgcaaacggc aggcaaaaaa aataaccgct
    43501 tcaaggcggt tttttggtgg ccagaggcgg aatcgaaccg ccgacacacg gattttcaat
    43561 ccgttgctct accaactgag ctatctggcc tttgtctgtc tcgttaagag atgcgtatta
    43621 aaccaaatta cgggacgaca tgcaagcata tcgggcaata ttctttgaaa acaggtttaa
    43681 gtcaatgttt taaatttgaa ttaatttatg taaaaacaac ataaatccgt atttttgccg
    43741 cctgcccgac gatattaggt cgcccgtctg aaaaatattt tcaatatttg aagttcttac
    43801 ccagataaac agaacgaacc tgttcgtttc cgaccaaatc atcaggtttt cccgatgcca
    43861 gcaccgcacc gtctgaaatg atgtaggcgc ggtcgcagat gctgagggtt tcgcgtacgt
    43921 tgtggtcggt aatcagtacg ccgataccgc gcgacttgag aaatccgatg attttttgga
    43981 tgtcgatgac ggcgatggga tcaacaccgg caaaaggctc atccagcaaa ataaaatgcg
    44041 gtttcatggc gagtacgcgg gcgatttcga cgcgccgccg ttcgccgccg gacagcgacg
    44101 gcgcggggct gcggcgcaag tgtccgatat taaggtcggc gagcagtttt tcgatttccc
    44161 tgtcgatttg atttttatct ttggttctga tttccaagat ggcgcggatg ttttgttcga
    44221 cggtcatttt gcggaatatc gaggcttcct gcggcaggta gccgacaccg aggcgggcgc
    44281 gttcgtgtat gggcaggtgg cgcaattctt gtccgtctag ggttacgctg cctgcgtcgg
    44341 cggcaatgag tccgactatc atgtagaagc tggtggtttt acccgcgccg ttgggcccga
    44401 gcaggccgac gacttctccg ctttcgattt cgagggagaa gcttttaacg acttggcgtt
    44461 ttttgaaact tttttgcagg ttttgaacaa caaggcggct gacgtttgcg ctcataaata
    44521 tctcttcaat atcttcggtc ggcaaatgcc gtccgaacca ggtttatgtt tcagacggca
    44581 ttttgggatt attcggattt ttgcgtactc gaaggctgga taacgacgct gaccctgccg
    44641 gatttggaag cggattttgc gccggatttt gtgctgccgc tgatggtata gacttcggtt
    44701 ttggtgttgt atgtaatcac cgcaccttcg gcgacatcgc cgccgcgctg tactttggca
    44761 ttaccggtta agactacggt gctgcctgca gatgaataag caacgttgtt tgcctgtccg
    44821 cgcaccgtgc ctttgccgcc gtccaatgtc tggctgaagc ggactggcga accttccgcc
    44881 ctcacggatt cgccgccttt gccgccgcgt gtaacattga cgcgggcggc ggaaatattg
    44941 agcgtaccct gtctgatgac gacgtttccg ctgaatgtgg tgctttggtt ggcttgatcg
    45001 agcgaacctt ggtcggcctc aatctgaata ggctgcctgc tgtcgctttg aagggcaaaa
    45061 gcgggggacg ccgaaaaaaa tgctattaaa acaaatagct tacatatctt ttgtatcata
    45121 aatcgtggct ttcactttag atgagaagtt caacatgcct gttttgtggt cgtaagtcat
    45181 gccgcccgcc tgaccgtgcg atgcaccata ttggaaactg acaggcgtat cggtttgggc
    45241 atattgagat tcggtatcga cgtgcagctt ttcggcttca actttacccg cctgccgttt
    45301 gccgtcggcg gttttggtca gcacaacgtt gtttttaaaa agaacctgtt tgttttcggt
    45361 atggtaaacg gcttcatcgc tgccgacttc gtacaacaac ctgccttctt ggaagaacac
    45421 gagatgcggt gagtcgaaat gaatgtcgct gctttcggga aactgtttcg cgcccttcga
    45481 actcaaatgt tctttcaagt atccctgttc gtcaaaccgc ctgccatcca atccgtccat
    45541 tgtgtattgc ggttcgtcgg gattgagcct gacttcttca atctcgactt cgctgatgcg
    45601 tcccaaccat gccgacaggc tgcccaaggc aaccgccaat atcaatggga acgcaattcc
    45661 gtaccgccat cttactttca tttgatgtac tcgttcaaag ccgcgcccaa agtcccttgc
    45721 gcctgcataa tcaggtcgca cacttcgcgc accgcgcccg caccgccggg gcgtttggca
    45781 atataggcgg cgtgttgcag cgtaaaccaa tgcgcgtcgg ggacggcaac cggcaatccg
    45841 cagcgtacca taacgggcaa atcgaccacg tcgtcgccga caaaggcaca ctcggcttct
    45901 tccacgccga cctgagcgcg cagctcttca tacgcggcgc gtttgtccga aatgcctttg
    45961 aagtagtaat ttatgcccaa ctgtttgacg cggatgccga cggagggcgc gtcccgacct
    46021 gtgataatcg cagtctgcac gccgcttgcc tgaagcattt tcagaccgtg tccgtccagt
    46081 gtgtgaaacg atttgatttc ttcgccgtta tcgcggataa agatgcgccc gtcggtcaaa
    46141 acgccgtcca catccaggat caacagtttg attttggcgg cgcgcgcctg taattcggga
    46201 gaaattgcct gcatgggatt tccttgtttt cagacggcat atcttaccac aaatgccgtc
    46261 tgaaacggct gcaacgcctt atatagtgga ttaacaaaaa tcaggacaag gcgacgaagc
    46321 cgcagacagt acagatagta cggaaccgat tcacttggtg cttcagcacc ttagagaatc
    46381 gttctctttg agctaaggcg aggcaacgcc gtactggttt ttgttaatcc actatacaat
    46441 ccgcgccgcc aaaaggtcgt gcatattcag cgcgccgatc agcacgccat ctgcatcggt
    46501 aaccagaagc ccgttcacat ggtttgcctg catgactttc agggcttcgg tggcgagacg
    46561 ttcggcggag atggttttag gatgcgtatg catgacttcg tctatcgaaa gaccggtaaa
    46621 attgtcgcat tcttgaaaca ggcggcgcaa atcgccgtcg gtgaatacgc ctttcagacg
    46681 gccttgcccg tccgttaccg ccaacatgcc cagccctttt tcactcatgc tgacgatggc
    46741 ttctttcaag ggcgtgccga gtcggacggc aggcaggccg ccgcctttgt gcataatgtc
    46801 ggcaacgcgc aaaagtaggc gtttgccgag gctgccggca gggtggctca aggcgaagtc
    46861 gtcgggcgtg aacgcgcggg cgcgcagcag gacaaccgcc aacgcatcgc ccaaagccat
    46921 aacggcggtg gtgctggtgg tcggggcaag ccccagcggg caggcttctt tggaaaccga
    46981 cgccgtgatg tggatgtcgg catggcgcgc catggttgaa tcggggcggg cggtgatgca
    47041 gacaagcgtg atatctttgc gtttgagcgc ggggatgatg gcggcgattt cgtcgctttc
    47101 accggaattg gaaatcgcga cgaccacgtc gttgtccaca atcatgccca aatcgccgtg
    47161 tgccgcttcc gcagggtgga cgaaaaacgc gggcgtgccg gtcgaggcca tggttgccgc
    47221 cattttgcgc ccgatatgtc ccgacttgcc catgcccgtg ataacgaccc tgcctttgca
    47281 gtgcaacaac gcgtccgccg caagggcgaa gttttcgtcc aaatccgccg caatttcgcg
    47341 caagccttcc gcttcggtgt gcaacacttc gcgtgcccaa tcaagatatt tttcgtttcc
    47401 tgccatcgcc atccgccttt gctgtaataa aactacccaa aatttccgaa tcggggtagc
    47461 ataagccttt gaaacataca catccatcca aaggaatcag aaatgactat tttatcggac
    47521 gttaaagcat taggacaaca aatctggctg gacaaccttt cccgctcgct cgtgcaaagc
    47581 ggcgaattgg cgcaaatgct gaaacaaggc gtgtgcggcg taacttccaa tcccgccatc
    47641 tttcaaaaag ccttcgccgg cgatgcgctt tacgccgacg aggttgccgc cctcaagcag
    47701 caagacctga cccccaaaca acgctacgaa acgatggcgg ttgccgatgt gcgtgccgcc
    47761 tgcggcgtct gtcttgccga acacgaatcc accggcggca aaaccggctt cgtcagcctc
    47821 gaagtttcgc ccgaattgtc caaagacgcg caaggcacgg ttgaagaagc gcgccgcctc
    47881 tacgccgcca tcgggtgcaa aaacgcgatg attaaagtgc ctgccaccga cgcaggcatc
    47941 gatgcgctcg aaaccctcgt ttcagacggc atcagcgtga acctgaccct gctgttctca
    48001 cgcgcccaaa ccctcaaagc ctacgccgcc tacgcgcgcg gcattgccaa acgcttggca
    48061 gccggacaaa gcgttgccca tatccacgtc gtcgccagct tcttcatctc gcgtgtggac
    48121 agtgcgctgg acacaacact gcccgaccgg ctcaaaggca aaatcgccat cgcccttgcc
    48181 aaagccgcct atcaagattg ggaacaatat ttcaccgccc ccgaatttgc cgcactggaa
    48241 gcccaaggcg caaaccgcgt gcagctttta tgggcatcta ccggcgtgaa aaacccagcc
    48301 tatcccgaca cgctctacgt tgacagcctg atcggcgcgc acaccgtcaa caccgttccc
    48361 gatgccacgc tcaaagcctt tatcgaccac ggcacagcca aagccacgct gaccgaaggc
    48421 gcggacgaag cgcaagcgca gcttgccgaa attgccgcgc tcggcatcga tgtcgaaacc
    48481 ttggcggcgc gtttgcagga agacggtttg aaacaatttg aagaagcctt tgaaaaactg
    48541 ctcgcaccgt tggtttaaac ttttcatccc gatgccgtct gaaaggcttt cagacggcat
    48601 cgcccgtttg accggacaca gtgcggcata tcaaggattc accctaaaaa tattaatggg
    48661 caagaagtta atgcacgaca ttacccacca acacaaaagg aaatagaatc atggcaaaag
    48721 cactcgaaat catttcaccc aatgaaattt attcagatct gatttttaag gatccggtac
    48781 ctccccatac aatatataca gaattgatga aactggttag tagaaatgca agtaatgaga
    48841 gaatcgcaga tagagccttc gattttttct cgtccggcct tatggatggt tcagctaccg
    48901 aagagcaata taatgcccta tatgatttaa ccttacttga agaacccggg atggaactga
    48961 ataaagatga gataatggct ttgattaata gtcttaaata aaggggccgt accggatatg
    49021 tacacaggac gtttcgcccc cagcccgacc gggctgctcc acatcggctc gctgctgacc
    49081 gccgccgctt cctatgccga tgcacgctca aacggcggca aatggctggt ccgcatggaa
    49141 gacctcgatc cgccgcgcga aatgccgggg gcggcaaacc atatcctgca cacgcttgag
    49201 gcattcggat tcgagtggga cggagaagtc gcctatcaga gccgccgtta cgccctgtat
    49261 gaagaaacac tatgccgtct gcaaaccgcc ggactggtct atccctgcca ttgcagccgc
    49321 aaagactggc agaccggggc aaggcggggc gcagacgggt tcgtctataa cggacgctgc
    49381 cgcaatccgc agcaacgccc tgcaccgcaa ggcaaacagc cggcgtggcg catccgcgtc
    49441 cccgaccgcg ttatcggttt ttcagacggc atcgtcggcg gttacgccca aaacctcgcc
    49501 ggcgacatcg gcgatttcgt cctgcttcgt gcagacggtt actgggcata ccaactcgcc
    49561 gtcgttgccg acgatgccga acagggcgtt acccacatcg tccgcggaca agacctgctc
    49621 gtttctacgc cgcgccaaat ctatttgcag cagtgtttgg acgttccgac accgcaatat
    49681 gcccacctgc cgctgctgac caacgcacaa gggcagaaat ggtcgaaaca gacgctcgca
    49741 cccgcattgg atttaaaccg ccgcgaacaa ctcctccgcc aagtgttccg ttacctcaac
    49801 ctgcccgaag caccggaagc cgaccgccct gccgaactgc tcgactgggc ggtggcacac
    49861 tgggatatgg acaaagtgcc gaaacacgcc attaccaccc cctaaacacc gcccgacaaa
    49921 cgcacaaatg ccgtctgaag ccttcagacg gcatttcaca catacagccc cgccctattc
    49981 gcgcgtattt gcccgttcga cctctttcca cgcttcgaga atcaggctgc cgtcgttgtc
    50041 tttcaagagc gttgcgtcgg aaagcatacg ccgccaagtc cgcgcgcctt tcaagccgtg
    50101 catcagcccg aggctgtggc ggacgatatg gcgcaggatt gtgccgcgtc cggcttggat
    50161 ttgggcttgg ctgtatgtgt agaggcgttg caccaaatcg gcgtatccga tcgggttcgc
    50221 agtgtcgccg taaaacaatc tgtcccattc gcgcatcacc atcgggttgt ggtacgcctc
    50281 gcgcccgacc atcacgccgt caacgtgttg caggtgtccg gcgattgctt cgttggtggt
    50341 gatgccgccg ttgatgatga tttccagccc gggaaactcc tgcttgaggc ggtaaacgta
    50401 atcgtatttc aacgggggaa cgtcgcggtt ttctttgggg gaaagaccgt ccagccaagc
    50461 gttgcgggcg tggacgatga aggttttgca ggcggttttg tcgcgcaacg tgccgacgaa
    50521 atcggcaacg gtttggtatt cggtctgcct gtccacacca atgcggtgtt tgacggtaac
    50581 gggaataccg accgcgtcct gcatggcgtt gaggcagtcg gcaaccagcc cgacttcgtt
    50641 catcagacac gcgccgaacg aacctttctg cacgcgcgga ctggggcagc cgcagttgag
    50701 gttgacctcg ttgtagccgt atgcttcggc ggctttggcg gctttcgcca aatcggacgg
    50761 atcgctgccg cccagttgca gggcgacggg ctgctcgcct tcgttgaaca tcaaaaagcg
    50821 gtctttgtcg ccgtaaacaa tcgcaccggc attgaccatt tcgctgtaaa gccaagcatt
    50881 tcgggtaatc tggcgcgcca tataacggta gtgcctgtcc gtccagtcga gcatcggggc
    50941 gacggaaagg cggcgcgggg gaagggtgtg tgtattgtcg ttcattgtcg atatttcatc
    51001 attgcagatt caatttcaat ccggaacaac cttcattttt ggggaaatcc gcgtcatgaa
    51061 agagtccagc agtatggtta ccggcccgtc gttgcagagc gacacctgca tatgcgtgcg
    51121 gaaacgccct gtttcgacat gaatcccgtg tccgcgcaac agttccgccg ttcgcaggta
    51181 aagctgctgc gcctgttctg caggtgcggc ttgggaaaac gaaggccgcc gcccgcttgc
    51241 cgcatcggca taaagtgtaa actgcgacac cagcagcacc gcgccgccga catctttcaa
    51301 agacaggttc aacttgcccg cttcgtcttc aaacacgcgc aaatgggcga ttttgtcggc
    51361 gatatagtgc gcatcttttt ctgtgtcgct atgcgttacg ccgagcagca cgacgaatcc
    51421 gccgtcgatt ttgccacagg tttccgtgcc gttttcggac acgacatcca cctttgcacc
    51481 taccgttttc tgtatgaccg cacgcataag ccgtcctcct tacctgaacg tgcaatgccg
    51541 tctgaaaagg cttcagacgg catcggtatt ggaaatgcca ttacggtttg acaccgtttt
    51601 cttccaaaat ggcatcgatt ttcaagcggg ctttttcctg tctcaaacct tgttccaact
    51661 ggtttctgac caactcgaaa ggctgcgcgt cggggttttt cccgacctcg ctgagtttga
    51721 acagataata gcgttcgccc aatttgaccg gatcgcgggt aacgtcgccc cgattcatcg
    51781 ctgcaaactg cgaagccagc ggctcgggaa gctgctgcgc cataatgaaa ccgtcaaaag
    51841 cctgctcgtc gttcggataa cgcttcatca gcccttcaaa agacagccct ttgagcagga
    51901 gctgctgcgc ctgacgcgcc tcctcttcgg ttgcgaagct gacctgctgc aatttgatca
    51961 tgcggatttg ccgctcataa aattgacgca gtgcgctttc ggaaaccgtt tccgaacgtt
    52021 ccagaaaacg gacgtactcc tcggcataaa aagacgcttc ggcgatttta aagcggtttt
    52081 ggacatcctt atccttatcc aaaccttcct tcaatgccct gtttttcaaa acttccaaag
    52141 tttgcagccg acggacggca tcgtttcgga ttgcctgccc gtccggtttt tgggactgct
    52201 ccgcatgccg gtctgcctgc tgcatgatct gcgccaccag cgtatccacc aaagccgggt
    52261 cgatttcggg tgctttggct gccgcaaaac ctgccaacat tgcagcaata actgcggcag
    52321 cggttttttt ctgtttcatg gtattccctg tcctgcgcgg cggcaaaacg cctgtctgaa
    52381 cgtcttgccg ccgtatcccg ttttcagaat tattttgcag gtttgatgtt tgccttgccc
    52441 aacagtgcac cgacggcacg gtcaatccgt tccgcctgaa ggttgccggc aatctgtcct
    52501 ttcatttcat caaaagaagg cactttcacc tcgcggctgt cgttgacata ataaacgccg
    52561 tagaaatcgc cgtttttcag cggcgttgcc gtaaattcgc cttttttcaa gtccttaatt
    52621 gcctgataaa gcggcggaac accctgttcc aaatctttca gcggcacata tccgaccggc
    52681 gcgccggtct gtttggtacg gtcgttgagg gaatattgtt tcaagacggc atcgaaacct
    52741 tttttcgcct tcaagtcggc aaccgctttt tttgcatttt cttccttgtc ggtcaggatt
    52801 tcgcccaact ggacttcctg cgtacctttg taaaaaccgc tgatattgtc atatgcggct
    52861 tttacttcct gctcggaaac cggttgggtt ttggcgatat gcagcgcgta tgcctcgccg
    52921 ttcaagccat attttaccgc ctgccaaacg gttttgaagg acggtttctt gtcgtcgccc
    52981 gactttttcg cttcggcacg caatttggca agcgcatttt taaactctgc cgaccggtcg
    53041 agtttcaggc gtttcacttc ctgtgcgacc acggtgttga ccacttcgtt ttccagcagg
    53101 gattggcgca gttgcggcgt gtcttcggca cggctgtttt ccgcacggaa tgcggcaacc
    53161 tgcgcatcga tgacggaact gtcgattttc tgaccgttga cggttgccag cgtttgggca
    53221 aacaggctgc cggaacaggc aagcagtgca acggaagtca ggatttttgc tttcataatc
    53281 ttctctcttt aaattttaaa ttgaaatgtt cgggcagact tcattcagtc cgccgtatgg
    53341 aaatactcgt caggggtagc cgcccggatg ccgagcgcgt gaatcatgcc gcctgaaaac
    53401 aaatctttga gcagcgattt gaccgttttc tggcggttca ggcggcttac gccttcaaaa
    53461 cggccgctaa cgaccaaaac ggcataatgt ccgccgccgg tattgcccgc gtgtcctttg
    53521 tgcagatggc tctcatcgcc gatttccaac accagcggat cgagcgtctg caggcgttcg
    53581 cggatcaaat cgacggccgg cattatttga acaccgcttt aaacggcttg atcagcactt
    53641 cgctgtacac gcctgcatga acatagggat cgtcttccgc ccacgcctct gccgcatcca
    53701 aagactcgaa ctgcgccaca atcaaactgc ccgaaacgcg gttggagtcc tccggcaaag
    53761 gattcgggcc tgccgtcaac agccggcctt ccgacttcag cgtctccagc cgtttgaggt
    53821 gttcgggacg tgccgccata cgcgcttcat acacattctc cccgtctgtt gccagcaaca
    53881 taaaatattc cacagtcaat cctccttttt cagacaggta ctcagataaa taccctgaat
    53941 aataaagaaa acaagcatca gtgcagtcga gccgaacatt ttatagttga cccattgcga
    54001 ctcgaaccgg gtaaacacaa accagttggc gatacccata aaaatcagga aaccgaccca
    54061 catatacgtc aatttcgccc atacggcatc cggaagctga atctccctgc cgatactcgc
    54121 cttcaagccg tttttaccgg cgaggtggct gccccacagg aacagcgcgc ccagccaaaa
    54181 caaaacgctc ggcttccaca taatgaagcg gctgtcgccc aaaacaatgg ttgcgccacc
    54241 gaatatcaca atcagcacca gtccgaccca ctgcatcgta tccagctttt tatatttcca
    54301 atacagaaaa gccgcctgaa ccacaccggc aaccaaggcg accgccgtag cggcaatcat
    54361 atttttggta acggtatagg tggcgaaaaa caggatgacg gacaaaaggt cgctgacgaa
    54421 tttcatatcc aaatgagaaa gcaaatcaaa taaacgctaa tcatacaggc agaaccctgt
    54481 ttttgcacct gcaaaaccaa caaattttgt tttgattgat gcaaatatgc acagatgttt
    54541 ttgaaaaaag atggagatat gtcataattt gtaaaaacgg cgaatgattg ccgtttaaaa
    54601 tgtggcggcg gtcggtacat tcacatatta aatgcccgcc ggccgactgc cccgccgatg
    54661 cccgatgatg acgaaattta cagactgtac gcggtcaaac cgtattcagc cgccaaccca
    54721 caggggatac atcttgaaaa acaacagaca aatcaaactg attgccgcct ccgtcgcagt
    54781 tgccgcatcc tttcaggcac atgctggact gggcggactg aatatccagt ccaaccttga
    54841 cgaacccttt tccggcagca ttaccgtaac cggcgaagaa gccaaagccc tgctaggcgg
    54901 cggcagcgtt accgtttccg aaaaaggtct gaccgccaaa gtccacaagt tgggcgacaa
    54961 agccgtcatt gccgtttctt ccgaacaggc agtccgcgat cccgtcctgg tattccgcat
    55021 cggcgcaggc gcacaggtac gcgaatacac cgccatcctc gatcctgtcg gctactcgcc
    55081 caaaaccaaa tctgcacttt cagacggcaa gacacaccgc aaaaccgctc cgacagcaga
    55141 gtcccaagaa aatcaaaacg ccaaagccct ccgcaaaacc gataaaaaag acagcgcgaa
    55201 cgcagccgtc aaaccggcgt acaacggcaa aacccatacc gtccgcaaag gcgaaacggt
    55261 caaacagatt gccgccgcca tccgcccgaa acacctgacg ctcgaacagg ttgccgatgc
    55321 gctgctgaag gcaaacccaa atgtttccgc acacggcaga ctgcgtgcgg gcagcgtgct
    55381 tcacattccg aatctgaaca ggatcaaagc ggaacaaccc aaaccgcaaa cggcgaaacc
    55441 caaagccgaa accgcatcca tgccgtccga accgtccaaa caggcaacgg tagagaaacc
    55501 ggttgaaaaa cctgaagcaa aagttgccgc gcccgaagca aaagcggaaa aaccggccgt
    55561 tcgacccgaa cctgtacccg ctgcaaatac tgccgcatcg gaaaccgctg ccgaatccgc
    55621 cccccaagaa gccgccgctt ctgccatcga cacgccgacc gacgaaaccg gtaacgccgt
    55681 ttccgaacct gtcgaacagg tttctgccga agaagaaacc gaaagcggac tgtttgacgg
    55741 tctgttcggc ggttcgtaca ccttgctgct tgccggcgga ggcgcggcat taatcgccct
    55801 gctgctgctt ttgcgccttg cccaatccaa acgcgcgcgc cgtaccgaag aatccgtccc
    55861 tgaggaagag cctgaccttg acgacgcggc agacgacggc atagaaatca cctttgccga
    55921 agtcgaaact ccggcaacgc ccgaacccgc tccgaaaaac gatgtaaacg acacacttgc
    55981 cttagatggg gaatctgaag aagagttatc ggcaaaacaa acgttcgatg tcgaaaccga
    56041 tacgccttcc aaccgcatcg acttggattt cgacagcctg gcagccgcgc aaaacggcat
    56101 tttatccggc gcacttacgc aggatgaaga aacccaaaaa cgcgcggatg ccgattggaa
    56161 cgccatcgaa tccacagaca gcgtgtacga gcccgagacc ttcaacccgt acaaccctgt
    56221 cgaaatcgtc atcgacacgc ccgaaccgga atctgtcgcc caaactgccg aaaacaaacc
    56281 ggaaaccgtc gataccgatt tctccgacaa cctgccctca aacaaccata tcggcacaga
    56341 agaaacagct tccgcaaaac ctgcctcacc ctccggactg gcaggcttcc tgaaggcttc
    56401 ctcgcccgaa accatcttgg aaaaaacagt tgccgaagtc caaacaccgg aagagttgca
    56461 cgatttcctg aaagtgtacg aaaccgatgc cgtcgcggaa actgcgcctg aaacgcccga
    56521 tttcaacgcc gccgcagacg atttgtccgc attgcttcaa cctgccgaag caccgtccgt
    56581 tgaggaaaat ataacggaaa ccgttgccga aacacccgac ttcaacgcca ccgcagacga
    56641 tttgtccgca ttacttcaac cttctaaagt acctgccgtt gaggaaaatg cagcggaaac
    56701 cgttgccgat gatttgtccg cactgttgca acctgctgaa gcaccggccg ttgaggaaaa
    56761 tgtaacggaa accgttgccg aaacacccga tttcaacgcc accgcagacg atttgtccgc
    56821 attacttcaa ccttctgaag tacctgccgt tgaggaaaat gcagcggaaa ccgttgccga
    56881 tgatttgtcc gcactgttgc aacctgctga agcaccggcc gttgaggaaa atgcaacgga
    56941 aatcactttg gaaacgcctg attccaacac ctctgaggca gacgctttgc ccgacttcct
    57001 gaaagacggc gaggaggaaa cggtagattg gagcatctac ctctcggaag aaaatatccc
    57061 aaataatgca gataccggtt tcccttcgga atctgtaggt tctgacgcgc cttccgaagc
    57121 gaaatacgac cttgccgaaa tgtatctcga aatcggcgac cgcgatgccg ctgccgagac
    57181 agtgcagaaa ttgctggaag aagcggaagg cgacgtactc aaacgtgccc aagcattggc
    57241 gcaggaattg ggtatttgat tcccaactgc cctttcgcag atcaaggatg ccgtttcaga
    57301 cggcatcttt ttttgcctta tcggtgtaac ggataaagtt tgaaccggca caggctcaaa
    57361 cagcaggtcg acggcaacaa aatgccgtct gaaaccccta aaggcttcag acggcattgg
    57421 cggcggcggt atcaggcagt ttgataggca accgaatcgt cgccgctttt cttttgaatg
    57481 aactcgattt tgtatccgtc ggggtcttcg acgaaggcta tcacggttgt gccgtgtttc
    57541 atcgggccgg cttcgcggac gacgtttccg ccctgccgct tcacacgttc gcaggcttcg
    57601 taggcatcgt ccacttcaac cgcgatgtgt ccgtaggcgt tgcccaagtc gtatcgttcc
    57661 gtatcccagt tgtgcgtcag ttccaaaacc gtgctgtcgg tttcatcgcc gtaaccgacg
    57721 aaggcaaggg taaatctgcc ttcgggataa tcttttcggc ggagcagttt catacccaaa
    57781 acgttttggt agaaatcgag ggatttttcg agattgccca cgcggagcat agtatggagt
    57841 aagcgcattt tttgtgttcc tttcggtggt ggttaaactt cgattttatt cggggtaaac
    57901 gtctgccatt tgttgcaggc ggggcagtgc cagaaaaaga cttgtgattt gaagtggcag
    57961 tttcggcacc ggtacatcac gctgcgctgt agctgccgtc cgataaccga acgcatcata
    58021 tcggcatcgg ctttccaagc cggatccaaa tcgctgagtt tcaaaccaag caggcggtac
    58081 acgccgttga ggtcgggctt gcggcggaca agctcgacgg cggtttgcgc ggcttctttc
    58141 tcgcacttaa gcagcaggga tttctcgtac acgacattga tcaggtcaag ttcgggaaac
    58201 gtctgcatat atcctgtcag acggttcaag ccttcttcag gttttccctg cgcggcatag
    58261 gcttcgtaaa gcttctcgcc gaccatgctc aagtatgcat ggttttgctg ctcgatggcg
    58321 gcataggctt cgacggcggc agggaaattg ccttgtcggt gttcgatgtc gcccaaaatc
    58381 atgttggcac gggtgcattt tttgttggct tcgagtgcct tgccgacatt gaaacgcgcg
    58441 acatcgaaat tggacttgaa cagcgcggct tgggcaagtt cgcaataaaa ctgggcgatt
    58501 tcaaactgat aggtctgatc gtcatggctg agcagccggg cggtttcaac cgctttttcc
    58561 caatccctgt cctgttggta gatattgagc aggtgctgtc tggcttcacg cgccatttta
    58621 ccgtcttgca gccccaaaaa aatctgttcg gcacgatcga ccaaccccgc actttggtag
    58681 ttttgcgcca attcaaacag gacgcgcgcg cgcttttcgc cgaccgtatc gggagaatcg
    58741 agcattgtcc ggtgtatgtt gatggctttg tcgttttcgc cacgctgacg gtaaagcttg
    58801 cctagggtga ggtttaggtc gtatgactga ggctgctgat caatgacctc tgccaattcc
    58861 ctggcggcac gtccgctgtt gcggtcaacc aaggcatcca gacttttata aaatcccgac
    58921 ggtatgcttt ttgcctgctt taatacagtc ttcatatcca cacgggcggc aaaccagccc
    58981 atcgcgaaga aaacgggcaa aaggataatc ggcagcagga taatccacaa ttcattgtcc
    59041 atatcggctt tctcaaggct gtttggcaga ttcgggcgca ttttgcgccg gtggtgcggt
    59101 cagctctttc cccgtcaaac gcgcattttt ctttacttcg gcacgcaacc tgccgttctc
    59161 gccacgtaac gacaacaacc gtccgaacaa ggcaaacatt ccgaacacga tgccgacgac
    59221 aaacgcgccg aacaatacga caatcagcgg caaatcgact ttctgtccgg gcaggtagga
    59281 gaaggtaacg gcatccgtat taatgacggc aagcagcagg aagagcagca ggataatgat
    59341 tttgatgacg gtatagataa gtttcatgtt tgctccgtaa ataaaaacgc cgcccggaca
    59401 gcttcgcact ctgaaccaag attgcgctag tttaaacgat ttgcacggtt tcggatagga
    59461 tgcggcagcg tgttcggacg acatacggag tatgcgattg ccgacaattt taccaaatac
    59521 accgttcctt tccatttgaa aaataacgga ttggacaccg catcgacaga aaaacccgcc
    59581 gcgcacttgt caaaaccctg tttgcaggcg tatctttaca atcttcaaat tcaaaccgtt
    59641 cattgaaaca tatcagaata agaaaggctt tacatcatga gcagacccgt acccgccgta
    59701 ttcggcagcg tttttcacag tcaaatgccc gtcctcgcct accgcgaagg caaatggcag
    59761 ccgaccgaat ggcaatcttc ccaagacctc tccctcgcac cgggtgcgca cgccctgcac
    59821 tacagcagcg aatgtttcga gggactgaaa gccttccgtc aggcagacgg caaaatcgta
    59881 ctgttccgtc cgactgccaa catcgcgcgt atgcggcaaa gtgcggacat tttgcacctg
    59941 ccgcgccccg aaacccaagc ctatctcgac gcgctaatcg aattggtcaa acgcgccgcc
    60001 gatgaaattc ccgatgcgcc tgccgccctg tacctgcgtc cgaccttaat cggtaccgat
    60061 cccgtcatcg gcaaggccgg ttctccttcc gaaaccgccc tgctgtatat tttggcttcc
    60121 cccgtcggcg actatttcaa agtcggctcg cccgtcaaaa ttttagtgga aaccgaacac
    60181 atccgctgcg ccccgcatat gggccgcgtc aaatgcggcg gcaactacgc ttccgccatg
    60241 cactgggtgc tgaaggcgaa agccgaatac ggcgcaaacc aagtcctctt ctgcccgaac
    60301 ggcgacgtgc aggaaaccgg cgcgtccaac tttatcctga ttaacggcga tgaaatcatt
    60361 accaaaccgc tgaccgacga atttttgcac ggcgtaaccc gcgattccgt actgacggtt
    60421 gccaaagatt tgggctatac cgtcagcgaa cgcaatttca cggttgacga actcaaagct
    60481 gcggtggaaa acggtgcgga ggcgattctg accggtacgg cagccgtcat ctcgcccgtt
    60541 acttccttcg tcatcggcgg caaagaaatc gaagtgaaaa gccaagaacg cggctatgcc
    60601 atccgtaagg cgattaccga catccagtat ggtttggcgg aagacaaata cggctggctg
    60661 gttgaagtgt gctgatgctt taaataaaaa aatgccgtct gaaacccgtt tggcgtttca
    60721 gacggcattt tcgcgttcgg accatttccg ctgcacctgc agcaagtcgg gcatttccct
    60781 agaaatacgc ttcagacggc aaaccgccgc ccgaaaccga tacgcggtac ggacggcgca
    60841 cggatttgaa aacggcggat tatccctcgg tgctcaaggc attaatgctg taaccgccgt
    60901 caacgtaagt gatttcgccg gtaatgccgg acgacaggtc ggacagcagg aaggcggcgg
    60961 tattgccgac ttcttcaatg gtaacgttgc ggcgcagcgg attgtgggcg gcgacgtgtc
    61021 ccaaaagttt gccgaaatcg gcgataccgg aggcggcaag cgttttaatc gggccggcgg
    61081 aaatgccgtt gcagcggatg ccttctttgc ccagacaggc ggcggtaaaa cggatgcccg
    61141 cctcaaggct ggcttttgcc atacccatca cgttgtaatt tggaatcgcg cgcaccgcgc
    61201 ccaagtagct cagggcaacg atggcggagt ttctgccgcg catcatcgga cgggcggctt
    61261 ttgccaatgc gggcaggctg tatgcggaaa tttcgtgtgc ggtgttgaac gcttcgcggc
    61321 tgatgctgtc gaggaagtcg ccgctcaagg cttctttcgg cgcgaagccg atggaatgca
    61381 ccaaaccgtc caagccgtcc caatgtttgc ccaagtcggc gaacacttgg ttgatttcgt
    61441 cgtcgctggc gacatcgcag cggaatacga gttcggaacc caattccgcc gccattttgc
    61501 ggacgcgctc ttccagtttg tccacaacgt aggtaaacgc cagttccgcg ccttgttcgc
    61561 ggcaggcttt ggcgatgcca taagcgatgg aacgctcgga aatcatgccg gtaatcagaa
    61621 tttttttgcc ttgcagaaaa cccattttgt atccttcaaa tagtgttcgg ttcattctaa
    61681 accgttgatt atagcaaatt gtccctgttt ctgtgttttc acgttgcagc atgcaaacgg
    61741 caatgccgtc cgaagcggat ttcagacggc atcggacgtt tcaaatacgg tttaaggcat
    61801 cagatgccgc gcaacaattc gttcacgctg gttttcgcac gggtttgcgc gtccacgcgt
    61861 ttgacgatga cggcgcagta aaggctgtgg ctgccgtctt tggaaggcat actgccggac
    61921 acgacgaccg aaccggccgg tacgcggcct tggtagattt cgccggtggt gcggtcgaag
    61981 attttggtgg attgaccgat gaacacgccc atagaaatca cgctgccttc ttcgacaatc
    62041 acgccctcaa cgatttcgga acgcgcaccg atgaagcaat tgtcttcaat aatggttggg
    62101 ctggcttgca ggggttcgag tacgccgccg atgccgacac cgccgctcaa gtggacgttt
    62161 ttgccgattt gcgcgcaaga gccgacggtc gcccaagtat cgaccatcgc accttcgtca
    62221 acgtatgcgc cgatgttgac gtaagacggc atcagcacga catttttcgc cacaaagctg
    62281 ccgcgtcggg caaccgcacc cggaacggcg cggaagcctg cgtttttgaa ctcgtcttca
    62341 gaccagtcgg caaacttggt cggcactttg tcgaagtatt tgttcacacc gtcgttgagg
    62401 atttcgttgt cttggatgcg gaaggacagc aacacggctt ttttcgccca ttcgttaact
    62461 ttccattcgc ccacgcccaa gcgttcggcg acgcgcagtt tgccggaatc gagttggcgg
    62521 atggtttcca acacggcttc tttaacttcg ggagtaacgg tggtcggatt aatgtccgcg
    62581 cggttttcaa aggcggtttc gataatgttt tgcaaagaca taatgtttcc ttatgtgaga
    62641 tgtttcgtgg gacgcttgcc ggtattttca agcagtatgt tcatttgaaa tgaatgcgct
    62701 attgtgccac gcaaacgcat attcgtcagc aatacgcggg cggttgccga acattggcgt
    62761 ttcggaatcg ggcgggcggc agtaccttta tgccgcaccg ccgcctttca gacggcattc
    62821 gcggtaaaac gccatcagcc cttcggtcga ggcatcgtgt acggacgtgc cgccttccag
    62881 ttcgccgatg atggtttttg ccaactgttt gccgtattcc accccccact gatcgaaggg
    62941 gttgacgttc catatcgcgc cttggacgaa ggttttgtgt tcgtaagccg ccatcagcat
    63001 acccaaattg tagggcgtga ggcggtcgag caggatgctg ttgctggggc ggttgccagg
    63061 gaactctttg tgcggcgcga ggcgttcgcg ttccgcttcg ggcaaatctg ccagttcggc
    63121 gcgtgcttcg tccaaggttt tgcccttcat cagggcttcc gcttgggcaa aggcgttggc
    63181 aacggtaaaa cggctgcgtc cgtcctccac gccctgcgcc gtcatcggga cgataaagtc
    63241 gcagggaatc aggcgcgtgc cttgatggag cagttggaaa taggcgtgct ggcagttgac
    63301 cccttcaccg ccgaacacga tgccgcccgt tttgcacacg gcgggactgc cgtctgaagc
    63361 gcggcttttg cccaaactct ccatatcgag ctggttcagc cacaccggca gcaggcgcag
    63421 gttgtggctg tacggaacgg cggtctgccc gtccgcgtgt tggaaattgt tataccacac
    63481 ggcaatcagt gccatcagaa cgggaatgtt gcggcgcggc ggcgtgtgga aaaaatggct
    63541 gtccatcgcg tgcgcccccg ccaacaactc gcggaaacgc gccccgccga ccgcaaccat
    63601 cacgggcaaa ccgacgggcg accagacgga atagcgtccg cccacccagt cgtacatcgc
    63661 aaacacgcgt tccgccgcga taccaaaagc cgcagctgcc gcagtgtcgg cagacaccgc
    63721 gcaaaaatgg cacgccgttt cggattccga gaaccccgca ccgcgatacc acgccttgac
    63781 tgcctgtgca ttgagcaggg tttccggtgt tttgaaggac ttgctggcaa cgcaaaacac
    63841 tgtcgtttcg gggttcagac ggcataaaac cgcatccagg caggcaggat cggcgttggc
    63901 ggcaaaatgg acggtgatat gccgtctgaa cggctcaagt gcctgcacgc acattgccgg
    63961 cccgaggtcg gatccgccta tgccgatgtg gacaaaatcc gtaatccgtt ttccggttgt
    64021 cccctgatac gaaccgtcgt ccaaactgtg tgcaaactcc aacgcacgat ttaactcgcg
    64081 gcggatttcg ggcaacacgt ccctgccgtc cgcataaacg gcatccgcac cgtcgggtag
    64141 gcgcaaagcc gtatgcagcg cggcacgccc ctcgctgccg ttgactttcg cacccgtccg
    64201 caaagcacgc attttccctt ccaaatccgc cgtctccgca agacggcaga gcagttgcag
    64261 cgtatcttcg cccaaacggt ttttgctgta atcgaacaac atcccgtcca aacgctcatg
    64321 catacgctca aaacggtcgg gttcgcaggc aaagcggtcg cgcaaaagga catgacgcgt
    64381 atcctgataa tggcgttcga gcgcatacca tgcacgggta aaagcattca tctgttttcc
    64441 ttgatttttc agaaccggat taaaatgtag cagaatgtag tttaacaaac ggcagcggct
    64501 ttggcgaatc tccggaacac cgcccgccgc gtccaatagc accttatttc catatggcga
    64561 aaatatagtg aattaacaaa aatcaggaca aggcggcgag ccgcaaacag tacaaatagt
    64621 acggaaccga ttcacttggt gcttcagcac cttagagaat cgttctctct tgagctaagg
    64681 cgagccaacg ctgtaccggt ttttgttaat tcactatacc ctccggccgg catttgaccc
    64741 gcaacaatat cctgcaagat ttattgtgta cgcataaatg ccggacagcc gcctaaataa
    64801 ggtataatcg catccgattc tgtcccgttt gccgcccgca ggcgggatgt cggcggtttt
    64861 catcttaccg ggaacacgcc ggtactgttt tttaacgatg tttcttacat tttattccaa
    64921 ttactttacg gggctagaat atggctaaaa acggaggatt ttctttgttc gcaaagaaag
    64981 aaaaacgctt tatctttgaa ggcaggcatt ccgcctccga caaactggtc aacggcgaag
    65041 tatccgcgtt taccgaagaa gaggcgcgca aaaaactggc aaaacgcggc atccgcccgt
    65101 tgcagattac ccgtgtgaaa acaagctcca agcgcaaaat cacacaagaa gacatcaccg
    65161 ttttcacccg ccagctgtcc acgatgatta aagcgggcct gccgctgatg caggcatttg
    65221 aaatcgtggc gcgcggacac ggcaacccgt ctatgacgga aatgctgatg gaaatccgag
    65281 gcgaagtgga acagggcagc tcgttgagcc gcgcattctc aaaccaccca aaatatttcg
    65341 accgcttcta ctgcaatctg gttgcggcgg gcgaaacggg cggcgtattg gaaagcctgc
    65401 tggacaaatt ggcaatttac aaagaaaaaa cccaggccat ccgcaaaaag gtaaaaaccg
    65461 cactgaccta tccggtatcc gtcatcgccg tcgccatcgg tttggtattc gtgatgatga
    65521 ttttcgtact gcccgccttt aaagaagttt acgccaatat gggcgcggag cttcccgcac
    65581 tgacccaaac agtgatggat atgtccgact ttttcgtctc atacggctgg atggtgctga
    65641 tcgcactggg ctttgccata tacggcttcc ttaaattgaa ggcgcgttcg attaaaatcc
    65701 aacggcgtat ggatgccata ctgctgcgta tgccgatttt cggagacatt gtccgcaaag
    65761 ggacgattgc ccgctggggc aggacgacgg cgacgctgat tgcggcaggc gtgcctttgg
    65821 tcgatgtatt ggactccact gccggcgcgg cgggcaattt aatctatgaa gaagccaccc
    65881 gggaaatccg tacgcgcgtc atccaaggtt tgtctatgac ttcggggatg cgtgcgacgg
    65941 aactgttccc caatatgatg ttgcagatgt cttccatcgg cgaggaatcg ggttctttgg
    66001 acgatatgct caacaaagcc gccgaatttt acgaagacga ggtggacaat gcggtcggca
    66061 ggctgtccgc tatgatggag ccgatcatta tcgtgatttt aggcttggtc atcggcacgc
    66121 ttctggtcgc catgtatctg ccgctgttta atttgggcaa cgtggtcgcc tgatttgccg
    66181 cacagatccg gcgcggattc gctctgcgcc ggtttgtttt tgttttgaat acattgagaa
    66241 caaaatatgt ctgatttgtc tgtattgtcg ccgtttgccg tgcctttggc agcggtgttc
    66301 gggctgctgg tcggcagttt cttaaacgtc gtcatttacc gcgtgccggt catgatggaa
    66361 cgcggctgga cggtatttgc caaagaatat ttaaacctgc cgctgaccga agaggaaagc
    66421 cgtaccttca acctgatgaa accggattcc tgctgtccca aatgccgcgt gccgatacgc
    66481 gcgtggcaga acatcccgat tgtcagttac ctgctcctgc gcggcaaatg cgcctcctgt
    66541 caaaccaaaa tcagcatacg ttatccctta atcgagctgc tgaccggcgt attgttcggg
    66601 ctggtcgcct ggcaatacgg ctggtcttgg attacgctgg gcggattggt actgaccgcg
    66661 tttctgattt ccctgacctt tatcgatgcg gacacccaat acctgcccga ctcgatgaca
    66721 ctgcccttga tttggctggg gctgatattt aatttggacg gcggcttcgt gcctttgcag
    66781 tctgccgttt taggtgcggt tgccggctat ggttcgatat ggcttttatg cgcggtatat
    66841 aaactgatta aaggcgaaat cggtatgggc aacggagatt tcaaactgat tgccgcattg
    66901 ggcgcgtggc tcggcatatc cgcattgccc gtgctgattt ttgtttcctc gctgatcggt
    66961 ttggtcgcgg caatcgttat gcgcgtcgcc aaggggcagc attttgcctt cggccccgca
    67021 ctgacagttt cgggctggat aatttttacg gcaaacgatt ccgtatggcg ggcggtcaac
    67081 tggtggctga cccatccggt gctgtaagat gacggtatgg gtcggactga ccggcggaat
    67141 cggcagcggc aaatcggcag ccgcgcaatg ttttgccgat ttgggcgtgc cgcgcatcga
    67201 tgcggacgcg gcggcgcact cgctgacggc ttcagacggc atcgccctgc cggaaatcag
    67261 gcggctgttc ggcgacaccg ttttcgacac acagggtttg ttgcgacgcg acatattgcg
    67321 taaagaagtc tttgcctccc catcgcgaaa agccttgctc gaatccgtga tgttgccgct
    67381 gattttctca gaaatcaaaa aacagcaaga aacctttacc gatgcggctt acggcattgt
    67441 cgaaattccg ctgctgacgg aaaagcgtca atttatcagc ctgatacggc gtgtcctgac
    67501 cataagcgca cctttggaaa aacgtatcgg cagggtgatg gcccgcagcg ggctgacgcg
    67561 cggcgaggtg gcggacatca tcagccatca ggcatccgaa tccgaacgcc tgctgcttgc
    67621 agacgatgtg ctgctcaatg acggcagcct caaaagcctg cgtgagaaaa caatgcgcct
    67681 gcacgcgttt tattcaggga ttttcgcctc aaaaccaaca caaggaaaac acaatgactg
    67741 aatcgcggca aacacgcctt caagtcaaat gtccgacctg tcaaacagca gtagtatggg
    67801 aacccgaaaa cgcattccgc cccttctgtt cgcaacgctg caaactgatc gacttgggcg
    67861 gatgggcaga cgggaaatat acggtttccg gccaaacgga aagtttgccg gaaatatccg
    67921 aacccgacat ggcataccgc tgaccgcccc gccttcccgg caaacaccct gaaagtcaaa
    67981 tgccgtctga aacaaacacg cttcagacgg cattttcatt ctcaaaccta atcgttggta
    68041 tttgccgtta cctcttccaa tgaagtaatg ccctgcataa ctttcaaaat accggcccgg
    68101 cgcaaatcca ccataccctc cttataggca acgtccaaaa tatccacttc cgtaccgttg
    68161 ttcataatca cacgctgcat ttcttcgctg atgggcataa cctcatacac gcccgcacgc
    68221 cccttataac cctgcccccg gcaacggtcg caaccgacgg cgcggtaaag tttccaatct
    68281 tttgcaaggt cctcatcggt gaagccgact tccttcaaag cagaggcaga cgggcgttcc
    68341 acttcctgtt tgcagctcga acacagcctg cgtaaaagac gctgcgccat aatcaggctg
    68401 accgaactgg caatattaaa cggcgcgaca cccatattca gcatacgcga caacgtcgcc
    68461 ggcgcattat tggtgtgcag ggtggaaaac accatatgcc ctgtttgtgc cgccttaatc
    68521 gcaatatcgg cagtttccaa atcacgaatc tcaccgacca taatgatgtc cgggtcctga
    68581 cgcaggaaag acttcaaagc agcggcaaaa gtcaggccct gcttatcatt gacgttaacc
    68641 tgattgatgc ccggcaggtt aatctcggca gggtcttccg ccgttgcaat atttaccgac
    68701 tccgtattca aaatattcaa acaggtatag agcgacaccg tcttacccga acccgtcgga
    68761 ccggttacca gcaccatccc gtagggacgg tgaatcgctt ccaacaacaa ttttttctga
    68821 aacggctcaa aaccgagctg gtcgatgttc aaagacgcgg catcggaatt caaaatccgc
    68881 atcacgacct tttcgccaaa cagcgtcggc aatgtgctga cacggaaatc gacaggcttg
    68941 ccgccctttt gaaaggtcag ctgcatcctg ccgtcctgcg gtatccgttt ttcggaaatg
    69001 tccaaacgcg acattacctt aatccgggaa gcaagctgcc cccttaccgc aatgggcggc
    69061 tgaaccacct cgcggagctg cccgtccaca cggaaacgga tacgggcatt gtgttcgtaa
    69121 aactcgaaat ggatgtccga tgccccgctg cgcaaggcat ccgacaaagt cttatggata
    69181 aacctcggaa cagggccgtc ttctgcctcc tcgttgtcga tatacagggt gtggctttcc
    69241 tcttcctcct gcccctcccc aagctcctga agcagcgatg tcgaacgcga acccacccaa
    69301 tcgagcaaac ccgccaactg gtcatcctcg acaatgacca actcaacctc aatccctgcg
    69361 gcagaaacgg ttttctgaat ttgcggcatc tgtgtcggat cggaaaccgc aaaaaatact
    69421 ttgtcgcccc gacggaaaac cggcacacag tggaactcca ccatctgctc ctccgtcaac
    69481 acccccatca gcaccctgtg gcgcggataa tgacgcaaat caagaatcga ataactgaac
    69541 acccttgcaa tcaatgccgc aagcgacttg ggcgaaatga cgccgtctga aaacagtatc
    69601 ggcaacactt ccttacccgc ctgcgactcc ttgtagtaat gctcggcctg ctcaacagta
    69661 accacctggt tttgaaccag aatcctcagc aaacctacgc tcatacgacc ttatccccaa
    69721 atttattcat tgttatacct gtacagcttt tatagtggat taaatttaaa ccagtacggc
    69781 gttgcctcgc cttagctcaa agagaacgat tctctaaggt gctgaagcac caagtgaatc
    69841 ggttccgtac tatctgtact gtctgcggct tcgtcgcctt gtcctgattt ttgttaatcc
    69901 actatatcat aaaacaacag atttccaagc cggaacatct tttacggagc ctgaaaatca
    69961 tttcatgatt ctaccgtcct aaaggtcggt ttttcaagca ggaagaaaaa gttttcagat
    70021 ggcaaaaaag ccctccaaca ctgaaaggcc ttatatcgga aacttcccgc aacacgggaa
    70081 acagacaaat gaaatcgtca aacctcgcca acaggaatcg aacctgtatt ttacgcttag
    70141 gaggcatacg ttctatccgt tgaactatgg cgagccgaaa tgaaaaggag attttaaccc
    70201 tttccgacga caaaagacaa gatgccggcc gcaatcagcg gcccgacagg gataccgccc
    70261 ataaatgcca ccccgataac cgtcccgatt aacagccctg taattaaaac aggctgctgt
    70321 cccatcaaag gcacgccgcg tcccgccagc caagccacga aaataccgat aaaaacggcg
    70381 gatatcattt taaaattcaa aaattcggca acgggaggaa cctgcgcctt tcctgaaacc
    70441 aacggactca aaacccctat ggtcaaaaga atgataccga gattcaaccc atgcttctcg
    70501 accaacggga caaactgtac caatgccgtc tgctgcatca gcagcaatat ggttgccgag
    70561 atggtaatcg aattgttgtt gctgaccacc cccaacagaa tcagcgtaac cagaaacagg
    70621 ggaacaaaac tgaaattcat cgcctcaaga caccctgacc aaagattcct tcgccagctg
    70681 aatcatggca tccttcactt cgctgtcggg cagggcatcc aaggcggtaa cggcacaatc
    70741 gactgctttg cgcgcctcgc ctatcgaata tgccaaagca tccgaacgga cgacataatc
    70801 gtggattttc tcaaaatagc tgcgatctgc attttccaaa gcagtacgca catcgttcgc
    70861 aacctgttcg gaaccctgac gcatcagata aatcaaaggc aaagtcggtt ttccttccgc
    70921 caaatcgtcg ccgacgtttt tgccggtttc ttcggtttcg ccagaatagt ccagcacatc
    70981 gtcaataatt tggaatgccg taccgacata cataccgtag tctttcaacg cccgttcgtg
    71041 ttcgggggaa gccttgccca aaattgcgcc gacctgcgcc gccgcttcaa acaattttgc
    71101 cgttttatat tggatgactt ggatatattg ttcttcggta atgtccgtat tgccgatgtt
    71161 catcagctgc atgacttcgc cctcggcaat aatgttggtt gcatccgcca tcacttccaa
    71221 aacgcgcata ctgcccgagg caaccatcag ttgaaaggcg cgcgtgtata aaaagtcgcc
    71281 aaccaacaca gccgccgcat tgccgaacag attgtttgcc gttgcccgcc cacggcgcaa
    71341 atcgctttca tcgacgacat cgtcgtgcag aagcgtcgaa gtgtggataa actcgaccat
    71401 cgccgccagc gaatacagtt tctcgtcatc ataaccgacc gccttacccg ccaaaatcgt
    71461 cataatcgga cgcaggcgtt tgccgcccgc gctgatgata tatgtaccga tttgcgaaat
    71521 cagtgcgaca tcggattgca ccgcacggtt gatgacttca ttgactttgg caaggtcttc
    71581 aggcagatgt cgctggaaat agggcagatt ctcgagcatg gcagactctc aggtttacgt
    71641 ttccgtcaaa cggcagatac cgcttgaaag ctgattcaaa tagcgggcaa ttatatcagc
    71701 aaagccatca gggtacatct tttcagacgg catatggtta tccgaaccgc gcaaactttg
    71761 acaaaacagg caaataacaa tacaatgccg agttccgcac aatggtgtgc ggatattaac
    71821 cataaccctt atggagttga gtatgtacgc ggtcgtaaaa actggcggca aacagtataa
    71881 agtttccgtc ggcgaaaaat tgaaagtaga acagatacca gccgaactcg acagccaaat
    71941 cgaactgacc gaagttttga tgattgctga cggcgaatct gtaaaagttg gcgcaccctt
    72001 tatcgaaggt gcaaaagtaa cggctaaagt agtggcacac ggtcgtggcg aaaaagtccg
    72061 catcttcaaa atgcgccgcc gcaaacacta ccaaaaacgc caaggccacc gccaaaattt
    72121 cacccaaatc gaaatcgtgg caatcgccta accttaaaac ttaggagcat tacaaatggc
    72181 aagtaaaaaa gcaggcggca gcacccgcaa cggtcgcgat tcagaagcca aacgcttggg
    72241 cgttaaagcc tacggcaacg agctgattcc cgcaggttcc atcatcgtcc gccaacgcgg
    72301 caccaaattc cacgcaggcg acaacgtagg tatgggcaaa gaccacactt tgttcgccaa
    72361 agttgacggt tatgtcgaat tcaaaaccaa aggcgcgctg aaccgcaaaa ccgtaagcat
    72421 ccgtccttac accggttctg aagaataatt caaccgaaca ggaagccgca tcttttcacg
    72481 atgcggcttt ttatagtgga ttaacaaaaa tcaggacaag gcgacgaagc cgcagacagt
    72541 acaaatagta cggaaccgat tcacttggtg cttcagtacc ttagagaatc gttctctttg
    72601 agctaaggcg aggcaacgcc gtactggttt aaatttaatc cactatacat accccacacc
    72661 cgatttgata cacattaagc tgaaagtaaa aatccgcata caccctcccc tgcatatttc
    72721 ttcaacagtg ggttttgata taatcgccta tctgttacag atagttcaaa cggcattcaa
    72781 acccttacaa ataccgtctg aaatcatcgg catccgtcta tgcaaaggat attttatgag
    72841 tttacacagc gacatcctcg tcgtcggcgc aggcccggcg ggtttaagtt ttgcagccga
    72901 acttgccggc agcggtttga aagttaccct gatcgaacgc agcccactga ctgttctgca
    72961 aaatcctcca tatgacggac gcgaaatcgc cctgacccat ttttcccgcg aaatcatgca
    73021 gcgtttgggt atgtgggaca aaattcccga aaacgaaatc taccctttgc gcgatgccaa
    73081 agtgctgaac ggacgttccg actaccagct ccactttccc caaccgaccg aggcgcgcgg
    73141 cgagcctgcc gactgtttgg gctatctgat ttccaaccac aatatccgcc gcgctgccta
    73201 cgaagtcgta tcccaactcg acaacattac cattctgacc gatacggccg ttaaagaagt
    73261 caaaacatct gacaacgaag cacaagtcat tttagaaaac ggcaaaatcc tgaccgcccg
    73321 cctgcttttg gcggcagaca gccgtttttc gcaaacccgc cgacaactcg gcatttcttc
    73381 agatatgcac gactacagcc gaaccatgtt cgtctgccgc atgaaacata ctctttccaa
    73441 ccaacatacc gcttacgaat gcttccatta cgggcgcacc atcgcactgc tgccgctgga
    73501 agaacacctg accaataccg tcattaccgt cgataccgat aaaatcaaca gcgttcaaaa
    73561 cctttcgccc gaagaattgg cggcaagcgt aaaagaacag ctcaagggca ggctcggcga
    73621 tatggaattg gtcagcagca tccaccatta cccccttgtc ggtatgattg ccaaacgttt
    73681 ctacggcaaa cgcagcgcgc tgattggcga tgcggcggtc ggtatgcacc ctgtaacggc
    73741 acacggcttc aacttgggtc tttccagcgc agatattctg gcaaaactga tactcgaagc
    73801 cgaacaacgc ggtcaggaca tcggcgcatc ttccttgttg gaaaaataca gcaacaaaca
    73861 tatgctgcac gcccatccgc tttatcacgg aaccaatatg atgctgaaac tgtttaccaa
    73921 cgaaaccgcg ccggcaaaac tgctgcgcgg tttggtattg cgtgccggca acaacttccc
    73981 gccgctgaaa aagctgatta ccaaacaact gaccggttga aaactgccga aatgccgtct
    74041 gaaacgtttc agacggcatt ttt
//
LOCUS       DAXISH010000004        63005 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.004, whole genome shotgun sequence.
ACCESSION   DAXISH010000004 DAXISH010000000
VERSION     DAXISH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 63005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63005
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.004"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..252)
                     /locus_tag="ACFOV4_000227"
     CDS             complement(<1..252)
                     /locus_tag="ACFOV4_000227"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFC7618320.1"
                     /translation="MVWKTLGEVFDLKNGYTPSKSNKEYWENGSIPWFRMEDIRENGR
                     ILDNSLKHISKSAVKGGKLFPAKSIMMSTTATIGEHALIK"
     gene            complement(385..876)
                     /locus_tag="ACFOV4_000228"
     CDS             complement(385..876)
                     /locus_tag="ACFOV4_000228"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFC7618321.1"
                     /translation="MDMQSKAKKLIEMIQTAPVEWKPLGGENGIAIIKTGQAVSKQKI
                     SNNIGSYPVINSGKEPLGYIDEWNTENDPIGITTRGAGVGSITWQEGRYFRGNLNYAV
                     TIKNRTELDVRFLYHILLEFEQEIHALCTFTGIPALNASNLKKLLIPIPPLETQQKNC
                     KNT"
     gene            complement(1042..2052)
                     /locus_tag="ACFOV4_000229"
     CDS             complement(1042..2052)
                     /locus_tag="ACFOV4_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HFC7618322.1"
                     /translation="MSIILYTANDGTAQFALQEFGGQLWLTQADMAELYQTTKQNISK
                     HIKTILAEQELEEKATVNFQLTVQNENGRKVNRKIAHYSLPMIIAVGYRVRSARGIQF
                     RQWATERLDEYLTKGFAIDDERLKGTGGGDYWKELLNRIRDIRSSEKALYRQVLDLYA
                     TSQDYNPKSSESQTFFAAVQNKLHYAASRQTAAELIYSRADSSKDFMGLTTFQGAIPT
                     LNEAKIAKNYLTEDELFRLNRLVSAFFDLAEIKAQEQSPMYMRDWIAELDKFSGLYGQ
                     GTLQGAGSISRKQAEQKAEREYRAYEARILSPVEQAYLESVKALEKTAVQQIKQKKDR
                     TK"
     gene            complement(2049..3593)
                     /locus_tag="ACFOV4_000230"
     CDS             complement(2049..3593)
                     /locus_tag="ACFOV4_000230"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFC7618323.1"
                     /translation="MMTEMQQRAQLHRQIWKIADEVRGAVDGWDFKQYVLGTLFYRFI
                     SENFTDYMQAGDSSIDYAAMPDSIITPEIKDDAVKVKGYFIYPGQLFCNIAAEAHQNE
                     ELNTKLKEIFTAIESSASGYPSEQDIKGLFDDFDTTSSRLGSTVADKNKRLAAVLKGV
                     AELDFGSFEDHHIDLFGDAYEYLISNYAANAGKSGGEFFTPQSVSKLIARLAVHGQEK
                     VNKIYDPACGSGSLLLQAKKQFDEHIIEEGFFGQEINHTTYNLARMNMFLHNVNYNKF
                     HIELGDTLTNPKLKDSKPFDAVVSNPPYSINWIGSGDPTLINDDRFAPAGVLAPKSKA
                     DFAFILHALNYLSGRGRAAIVSFPGIFYRGGAEQKIRQYLVEGNYVETVIALAPNLFY
                     GTGIAVNILVLSKHKDNTDIQFIDAGGFFKKETNNNVLTEEHIAEIVKLFADKADVPH
                     IAQNAAQQTVKDNGYNLAVSSYVEPEDTREIIDIKQLNAEISETVAKIERLRREIDEV
                     IAEIEA"
     gene            complement(3666..4670)
                     /gene="rfaD"
                     /locus_tag="ACFOV4_000231"
     CDS             complement(3666..4670)
                     /gene="rfaD"
                     /locus_tag="ACFOV4_000231"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008712 - ADP-glyceromanno-heptose
                     6-epimerase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HFC7618324.1"
                     /translation="MTIIVTGAAGFIGSNIVKALNQRGITDIVAVDNLSKGEKFKNLA
                     ECEIAHYLDKHEFIRQVREHILPYQNIEAVFHQGACSDTMNHDGLYMMENNYQYTLDL
                     LDWCQDERIPFLYASSAAVYGKGEIFREERELEKPLNVYGYSKFLFDQVLRRRMKEGL
                     TAQVVGFRYFNVYGQHEQHKGRMASVAFHHFHQYREHGYVNLFGSNDGYGNGEQTRDF
                     VSVEDVAKVNLYFFDHPELSGIYNLGTGRSQQFNELAAATVNACRAAEGKPEMSLKEL
                     VEEELIRYIPFPDALKGKYQSFTQADITKLREAGYTEEFFDVKSGVERYVKWMLENLA
                     "
     gene            complement(4711..5830)
                     /locus_tag="ACFOV4_000232"
                     /pseudo
     CDS             complement(4711..5830)
                     /locus_tag="ACFOV4_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221166.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(5832..7067)
                     /locus_tag="ACFOV4_000233"
     CDS             complement(5832..7067)
                     /locus_tag="ACFOV4_000233"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFC7618325.1"
                     /translation="MTISTMAQTHDTRLQKTLLFPSQQGWKSKTFLKPDSHIRLATVF
                     SGIGAVEQAFHRLNLNHTIVFAGDIDPYVKKSYLGNYKLNEDFWHNDITQFDARKFRN
                     QVDILVGGSPCQAFSMVGKRAGLEDTRGTLFYEFARVVDEVQPKIFIYENVKGLLNHD
                     NGKTWKVVKSVFYSLGYDLYFQIMNSKDYGIPQHRERIFVVGFHTPPINGFQFPEKIE
                     LEHTMQDFLEDYTDSKYFLREKGVKFVTSSKNRQKRYTQINGEIALCQKANQQFNWHG
                     DFIFQAARESEFDDFIFDVNNVEEKYYLSEKIKNYVLAGGTKNFKTSTETDLPVARPL
                     LQTMHKMHRAGVDNYVTHNRGRIRKLTPRECLRLMGFRDDFKILVSDTQMYRQAGNSI
                     VVDVLIAILKQMDITLYGE"
     gene            complement(7104..8075)
                     /gene="hldA"
                     /locus_tag="ACFOV4_000234"
     CDS             complement(7104..8075)
                     /gene="hldA"
                     /locus_tag="ACFOV4_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose synthase"
                     /protein_id="HFC7618326.1"
                     /translation="MSAKFQQETLKSRFAQAKVLVVGDVMLDRYWFGDVSRISPEAPV
                     PVAKIGRIDQRAGGAANVARNIASLGGRAGLLSVTGNDEAADALDALMVQDGVASYLM
                     RDKQIATTVKLRVVARNQQLIRLDFEEHPNCEVLEQIKQKYREILPEYDAIIFSDYGK
                     GGLSHISDMIDWAKHAGKTVLIDPKGDDYEKYVGATLITPNRAELKEVVGSWKNESEL
                     TEKAQNLRRHLDLTAVLLTRSEEGMTLFSEGEPIYQPTRAQEVYDVSGAGDTVIAGMG
                     LGLAAGCTMPEAMYLANTAAGVVVAKLGTAVCSFAELIKALSGQSTM"
     gene            complement(8130..8870)
                     /gene="pyrF"
                     /locus_tag="ACFOV4_000235"
     CDS             complement(8130..8870)
                     /gene="pyrF"
                     /locus_tag="ACFOV4_000235"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFC7618327.1"
                     /translation="MNPLISDFQTPQQRTPVIVALDFSNEKDTLGFVRNLDPTLCQIK
                     IGKELFTATGRNLAESLINQGFKLFLDLKYHDIPHTVAQACKVAADMGVWMVDMHASG
                     GRRMMEAAAEAVAGYGTKPLLIGVTVLTSMEQSDLAEIGLNTAPEEQVIRLAKLAQSS
                     GLDGVVCSAQEAAPLRRELGQDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAASTYL
                     VMGRPVTQAADPVAVLREVNRVANLEAN"
     gene            complement(9396..10043)
                     /gene="adk"
                     /locus_tag="ACFOV4_000236"
     CDS             complement(9396..10043)
                     /gene="adk"
                     /locus_tag="ACFOV4_000236"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004017 - adenylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFC7618328.1"
                     /translation="MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTP
                     LGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAMVEAGVD
                     LDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDK
                     EETVKKRLAVYHEQTEVLVDFYSKLEGEHAPKYIKVDGTQPVEAVKAEVLGALGK"
     gene            10258..11097
                     /gene="htpX"
                     /locus_tag="ACFOV4_000237"
     CDS             10258..11097
                     /gene="htpX"
                     /locus_tag="ACFOV4_000237"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HFC7618329.1"
                     /translation="MKRIFLFLATNIAVLVVINIVLAVLGINSRGGAGSLLAYSAVVG
                     FSGSIISLLMSKFIAKQSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHS
                     PEPNAFATGASRNSSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVV
                     NTFVVFLSRIIANLIARNNDGSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRA
                     DAGAAKLVGAPKMISALQRLKGNPVDLPEEMNAMGIAGDTRDSLLSTHPSLDNRIARL
                     KSL"
     gene            complement(11398..11958)
                     /locus_tag="ACFOV4_000238"
     CDS             complement(11398..11958)
                     /locus_tag="ACFOV4_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618330.1"
                     /translation="MTANFAQTLVEIQDSLYRVVSTVQYGDDNLKRLTADKRKQYELN
                     FKISEGSTRVESDFKETLVRFGRDMLQDMPPKIRSATLVALTTLLVGGALGYGYLEYL
                     KQVASEGYQTERLYNAVDRLAESQERITSAILKGARGADFVQIGRRSYSREDISEANR
                     RAERVPYGAELVSDGNFTAVLSDIGD"
     gene            complement(12072..12464)
                     /locus_tag="ACFOV4_000239"
     CDS             complement(12072..12464)
                     /locus_tag="ACFOV4_000239"
                     /inference="COORDINATES: protein motif:HMM:NF017109.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC7618331.1"
                     /translation="MGKRMTFDTAKSRFQEKFPHLELLEFSGIYKPSSVRCPTHGVVQ
                     LLYYDTAIKSKYGCPECGKLKMKENTPPQNQKPVSILDTATGETLTFPSVQAAAKALN
                     TPYGSIRTKLDGRSNPDNLVCNRYKVLL"
     gene            complement(12672..13064)
                     /locus_tag="ACFOV4_000240"
     CDS             complement(12672..13064)
                     /locus_tag="ACFOV4_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC7618332.1"
                     /translation="MAKSFNQAASELTDIFPNISLTGFDGVNYPVTVNCPMHGNVRYS
                     TFNALIKSKYGCPECAKMSKTQTPPNVGKPLLILDTTTNETLTFPSVTAAGAALGVHF
                     QQINHRLKGRTSPDNLISNRYKVLGYDR"
     gene            complement(13181..13591)
                     /locus_tag="ACFOV4_000241"
     CDS             complement(13181..13591)
                     /locus_tag="ACFOV4_000241"
                     /inference="COORDINATES: protein motif:HMM:NF017109.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC7618333.1"
                     /translation="MALTFTQAVSKLTSKFPHLNLVEFNGVRYPTVIVCPIHGRVTCS
                     TFKSMLDSKSGCPKCASYGVNSHKIPEDTIDKLSKNTVLEDTVTGETLTFPSRASAAR
                     SLGINPAAITDRIKGRVHTETLLAGRYKVHICTK"
     gene            complement(13605..13988)
                     /locus_tag="ACFOV4_000242"
     CDS             complement(13605..13988)
                     /locus_tag="ACFOV4_000242"
                     /inference="COORDINATES: protein motif:HMM:NF017109.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC7618334.1"
                     /translation="MPKSLSLQDVQLRFSSKFPDKTVLKFTKNYEPVTIQCPLHGSVV
                     YGNLQAAMKSSTGCPECTRNPEKPSPNAVAIRLEDTETGEIYEFASTLAASKFIGCSN
                     STLAVRLSGRTPFDRLIRYRYRLVK"
     gene            complement(14467..15765)
                     /locus_tag="ACFOV4_000243"
     CDS             complement(14467..15765)
                     /locus_tag="ACFOV4_000243"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFC7618335.1"
                     /translation="MAKNVVVIGAQWGDEGKGKIVDWLAEEAGGVVRFQGGHNAGHTL
                     VVGGKKTILRLIPSGILHESLDCFIGSGVVVSPEALLGEIDELNAAGVKNVEGRLKIA
                     PTCPLILPYHIALDQAREASRGKGKIGTTGRGIGPAYEDKVARRAIRAADLLHPEKLR
                     EKLDVVLAYYNVQLQHLHNAEPVKAEDVMAVIEKVAPRIAPMITDVSRVLNEKNKNGE
                     KLLFEGAQGALLDIDYGTYPFVTSSNCLAGAASAGAGVGPQMLDYVLGIVKAYTTRVG
                     SGPFPTELFDEVGAGLAERGHEFGSVTGRARRCGWFDAAALKRSIQINGISGMCITKL
                     DVMDGVETINICVGYELPDGGKTDILPCGSDAVEACKPIYETMPGWRESTFGVKDYGA
                     LPENAKAYLKRIEEVCGAPVAIVSTGPDREETIVLHHPFA"
     gene            complement(15869..17020)
                     /locus_tag="ACFOV4_000244"
     CDS             complement(15869..17020)
                     /locus_tag="ACFOV4_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HFC7618336.1"
                     /translation="MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPL
                     MEYAHSLLTHIDAGLSLKTILVTDRLSGRQLGIRADITPQVARIDAHLLSANQGINRL
                     CYAGPVLHAQSDGLLNMREPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLS
                     LGHIGIFRALSDAAHLDAGQSATLLALMQDKDTETVEAQVKAWKLDGMWAKAFSLLPR
                     LYGGREVLSDARGRLPDLSAVGGALGELQAVCDAFPDCEIHIDLSELRVDNYHTGLLY
                     AAYAADFHDAVARGGRYDGLGGYFGRARPATGFSFDLRSFIGRLPTIERQPAVLVDAE
                     DAEAAREAVEALREQGQCVVIDYGIGHNVSEELAGRLKKTDGVWQVVKR"
     gene            17355..18734
                     /gene="norM"
                     /locus_tag="ACFOV4_000245"
     CDS             17355..18734
                     /gene="norM"
                     /locus_tag="ACFOV4_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter NorM"
                     /protein_id="HFC7618337.1"
                     /translation="MLLDLNRFSFSVFLKEVRLLTALALPMLLAQVAQVGIGFVDTVM
                     AGGAGKEDLAAVALGSSAFATVYITFMGIMAALNPMIAQLYGAGKTDEVGETGRQGIW
                     FGLFLGVFGMVLMWAAITPFRNWLTLSDYVEGTMAQYMLFTSLAMPAAMVHRALHAYA
                     SSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGMPALGGAGCGLATMAVFWFSALALW
                     IYIAKENFFRPFGLTAKFGKPDWAVFKQIWKIGAPIGLSYFLEASAFSFIVFLIAPFG
                     EDYVAAQQVGISLSGILYMIPQSVGSAGTVRIGFSLGRREFSRARYISGVSLVLGWML
                     AVITVLSLVLFRSPLVSMYNNDPAVLSIAATVLLFAGLFQPADFTQCIASYALRGYKV
                     TKVPMFIHAAAFWGCGLLPGYLLAYRFDMGIYGFWTALIASLTIAAIALVWCLELCSR
                     EMVRSHKAV"
     gene            18913..19953
                     /gene="murB"
                     /locus_tag="ACFOV4_000246"
     CDS             18913..19953
                     /gene="murB"
                     /locus_tag="ACFOV4_000246"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFC7618338.1"
                     /translation="MQPIRYRTDLTPYNTFGLRAQARAFIALEHADGLRDIVRLPEFN
                     RDTVLWLGGGSNILLMEDYAGLVVHMENKGIREIARSDGMVLIEAQAGEIWHDFVLHA
                     VALGLNGLENLSLIPGTVGASPVQNIGAYGVEAKDVIHSVRCFDLDTETFVTLSNADC
                     RFAYRESLFKQEGKGRYVIVSVVFALKTHFVPNLGYGDLAAAVAELSAGRVPTAKDVS
                     DAVCAIRNSKLPNPNVLGNVGSFFKNPVIGAEKAAALLEQHPDMPHYPQPDGSVKLAA
                     GWLIDQCRLKGFQIGGAAVHDKQALVLVNKNNASANDVRQLAQHIKFTVFARFQVELH
                     AEPNWLPASFSL"
     gene            19965..20615
                     /locus_tag="ACFOV4_000247"
     CDS             19965..20615
                     /locus_tag="ACFOV4_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFC7618339.1"
                     /translation="MPVTRPAKINTYTRIIDASLALFNEEGERNISTNHIAAHLGISP
                     GNLYYHFRNKDEIIVQLFKRYSEALLAYLNEAVLPSDVEDSINYMAGIYDVMWEYRFL
                     FSDVNTLLARSAELLGEHNTFTQAKVSPLLVNLLTQLNGLNIIQADQTAMNDLAVNMW
                     MVTKYWFDFDSSLRGRTKLTEDSKARGIRRTLSLLRPYLLPEHRKKYDRKIGNGNP"
     gene            20670..21437
                     /locus_tag="ACFOV4_000248"
     CDS             20670..21437
                     /locus_tag="ACFOV4_000248"
                     /EC_number="1.1.1.290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFC7618340.1"
                     /translation="MRAVPPPHISITGLGYLGLPLAQKFYQHGSRVAAIKRSLTSDDI
                     NLPIHLDTFDLGSTDAFQTALWRHHADKPVWFFLLPPSSLTHYADTVKQWAELARACN
                     VQHLIFTSSTSVYGDTARECDETATPDPQTESARQILAAEQHLLDSGISNIDILRLGG
                     LYCAERHPVSRLVQKQNIPGGNRPINIVHRNIAVESLFQTAFNPGGRRLKNIIEPRHP
                     TRREFYTEEAAKLGFPAPDFAPDDSMGKIIRTVCDNS"
     gene            21497..22063
                     /locus_tag="ACFOV4_000249"
     CDS             21497..22063
                     /locus_tag="ACFOV4_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032934 - sterol binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HFC7618341.1"
                     /translation="MSALLPIINRLILQSPDSRSELAAFAGKTLTLNIAGLKLAGRIT
                     EDGLLSAGNGFADTEITFRNSAVQKILQGGEPGAGDIGLEGDLILGIAVLSLLGSLRS
                     RASDELARIFGTQADIGSRAADIGHGIKQIGRNIAEQIGGFSRESESANIGNEALADC
                     LDEISRLRDGVERLNERLDRLERDIWID"
     gene            22083..22973
                     /locus_tag="ACFOV4_000250"
     CDS             22083..22973
                     /locus_tag="ACFOV4_000250"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HFC7618342.1"
                     /translation="MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGI
                     KEGCIYTQDTVGCHIVNKTELGQYCDLVAVLGGDGTFLSVAREIALRAVPIIGINQGH
                     LGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGG
                     AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICP
                     QSMTNRPIAIPDTSEIEILVTQGGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHP
                     TDYQYFKTLRQKLHWGEQLV"
     gene            22998..23755
                     /locus_tag="ACFOV4_000251"
                     /pseudo
     CDS             22998..23755
                     /locus_tag="ACFOV4_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225415.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
     gene            complement(23810..24475)
                     /locus_tag="ACFOV4_000252"
     CDS             complement(23810..24475)
                     /locus_tag="ACFOV4_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFC7618343.1"
                     /translation="MTVLDREQVLSAFKNRKSCRHYDAARKISAEDFQFILELGRLSP
                     SSVGSEPWQFVVVQNPEIRQAIKPFSWGMADALDTASHLVVFLAKKNARFDSPFMLES
                     LKRRGVTEPDAMAKSLARYQAFQADDIKILDDSRALFDWCCRQTYIALGNMMTGAAMA
                     GIDSCPVEGFNYADMERVLSGQFGLFDAAEWGVSVAATFGYRVQEIATKARRPLEETV
                     IWA"
     gene            complement(24675..25448)
                     /gene="folE2"
                     /locus_tag="ACFOV4_000253"
     CDS             complement(24675..25448)
                     /gene="folE2"
                     /locus_tag="ACFOV4_000253"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase FolE2"
                     /protein_id="HFC7618344.1"
                     /translation="MNTIADVQSSRDLRNLPINQVGIKDLRFPITLQTAEGIQSTVAR
                     LTMTVYLPAEQKGTHMSRFVALMEQHSEALDFAQLHRLTAEMVALLDSRAGKISVSFP
                     FFRKKTAPVSGIRSLLDYDVCLTGEMKDGAYGYSMKVMIPVTSLCPCSKEISQYGAHN
                     QRSHVTVSLTADAEVGIEEVIDYVEAQASCQLYGLLKRPDEKYVTEKAYENPKFVEDM
                     VRDVATSLIADKRIKSFVVESENFESIHNHSAYAYIAYP"
     gene            25640..26797
                     /locus_tag="ACFOV4_000254"
     CDS             25640..26797
                     /locus_tag="ACFOV4_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aspartate aminotransferase family
                     protein"
                     /protein_id="HFC7618345.1"
                     /translation="MKFATKAIHSSYDCDEHNRALMPPIYQNSMFTLHEIGENVPYRY
                     SRLSNPTRQILEDTVADLEHGAAGFAFSSGMAGIDAVWRTFLQPGDTIVAVADIYGGA
                     YDLLVDVYQKWGVNVVFADLGNPDNLDELLKAHKVKLVWLETPSNPLLRLVDIKALAA
                     KAKATGALVGIDNTFATPYLQQPLDMGCDFVFHSATKYLCGHSDVLMGIVVAKTKELA
                     QPLHDMMVHTGAIAGPMDCWLVLRGIKTLALRMEAHCKNALEIARRLEDHPAIEKVFH
                     PGLPSHEHYELAQAQMPKGIGGVVTVYLKNDTREAANSVIKNMKLVKMASSLGGVESL
                     VNHCYSQSHSGVPHNVKMEMGIKVGLLRFSIGIEDADDIWNDISAALDTTL"
     gene            complement(26860..27861)
                     /gene="hemB"
                     /locus_tag="ACFOV4_000255"
     CDS             complement(26860..27861)
                     /gene="hemB"
                     /locus_tag="ACFOV4_000255"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HFC7618346.1"
                     /translation="MQFPYRNVPASRMRRMRRDDFSRRLMREHTLTADDLIYPVFVLE
                     GSAREEDVPSMPGVKRQSLDRLLFTAEEAVKLGIPMLALFPVVTANKTERAEEAYNPE
                     GLVPAAVRALRERFPELGIMTDVALDPYTVHGQDGLTDENGYVMNDETVEVLVKQALC
                     HAEAGAQVVAPSDMMDGRIGAIREALEDAGHIHTRIMAYSAKYASAFYGPFRDAVGSS
                     GNLGKADKKTYQMDPANTDEALNEVALDIREGADMVMVKPGLPYLDVVRRVKDEFGVP
                     TYAYQVSGEYAMLQAAIANGWLDGGKVVLESLLAFKRAGADGILTYYAIEAAKMLKR"
     gene            complement(28044..28328)
                     /gene="yhbY"
                     /locus_tag="ACFOV4_000256"
     CDS             complement(28044..28328)
                     /gene="yhbY"
                     /locus_tag="ACFOV4_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFC7618347.1"
                     /translation="MTDTKLNTKEILELKARAHHLHPVVMVGQQGLTDAVIKETDAAL
                     TAHELIKVRVFGDDRAERIEICTALCEAVDAQPVQHIGKLLVLWRKNIEG"
     gene            28438..29058
                     /locus_tag="ACFOV4_000257"
     CDS             28438..29058
                     /locus_tag="ACFOV4_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RlmE family RNA methyltransferase"
                     /protein_id="HFC7618348.1"
                     /translation="MAVRSKSSKAWLHEHVNDHYVHMAQKDGYRARAAYKLLEINDKD
                     KLIKPGTVLADLGSAPGSWSQVAAKLTGSSGAVFALDILPMEAIGGVSFIQGDFREND
                     VLAQFETLLDNRPLDLVICDMAPNMSGNAVSDQARSFYLCELALDFASQHLKTGGSFL
                     VKVFQGAGYQEYMAAMREIFGTVQTRKPEASRNRSSEIYLLGKNKR"
     gene            29122..31089
                     /gene="ftsH"
                     /locus_tag="ACFOV4_000258"
     CDS             29122..31089
                     /gene="ftsH"
                     /locus_tag="ACFOV4_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFC7618349.1"
                     /translation="MGNTFKSILVWVALGIGLMAAFNALDGKKEDNGQIEYSQFIQQV
                     NNGEVSGVNIEGSVVSGYLIKGERTDKSTFFTNAPLDDNLIKTLLDKNVRVKVTPEEK
                     PSALAALFYSLLPVLLLIGAWFYFMRMQTGGGGKGGAFSFGKSRARLLDKDANKVTFA
                     DVAGCDEAKEEVQEIVDYLKAPNRYQSLGGRVPRGILLAGSPGTGKTLLAKAIAGEAG
                     VPFFSISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRQRGAGLGGGN
                     DEREQTLNQLLVEMDGFESNQTVIVIAATNRPDVLDPALQRPGRFDRQVVVPLPDIRG
                     REQILNVHSKKVPLDKSVDLLSLARGTPGFSGADLANLVNEAALFAGRRNKVKVDQSD
                     FEDAKDKIYMGPERRSMVMHEDEKRATAYHESGHAIVAESLPFTDPVHKVTIMPRGRA
                     LGLTWQLPERDRISMYKDQMLSQLSILFGGRIAEDIFVGRISTGASNDFERATQMARE
                     MVTRYGMSDKMGVMVYAENEGEVFLGRSVTRSQNISEKTQQDIDAEIRRILDEQYQVA
                     YKILDENRDKMETMCKALMEWETIDRDQVLEIMAGKQPSPPKDYSHNLRENADAAEDN
                     APHAPTREETEAPAPADTASTESEQQPENKA"
     gene            31310..31741
                     /locus_tag="ACFOV4_000259"
     CDS             31310..31741
                     /locus_tag="ACFOV4_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RatA family
                     toxin"
                     /protein_id="HFC7618350.1"
                     /translation="MKKVEKNILVLHGADKMFELVDKVEDYPHFLPWYSKTEVIGRSG
                     NELKARLFMDYMHVRQSFATHNRNIPGREIRMELLEGPFKTLRGTWKFIDLGDDMCKI
                     EFNLEYDFSNAVLSALISPVFNHLSATLVEAFVKEADRRYA"
     gene            31734..32012
                     /locus_tag="ACFOV4_000260"
     CDS             31734..32012
                     /locus_tag="ACFOV4_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HFC7618351.1"
                     /translation="MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLN
                     LHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPKEARRKRVQNQEE"
     gene            32065..32643
                     /gene="pth"
                     /locus_tag="ACFOV4_000261"
     CDS             32065..32643
                     /gene="pth"
                     /locus_tag="ACFOV4_000261"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFC7618352.1"
                     /translation="MSNKIKMLVGLGNPGKEYEQTRHNAGFWFLDELAWKWKASFKEE
                     KKFFGEVARAALPDGDVWLLKPATFMNRSGQAVAALAQFYKIKPEEILVVHDELDIPC
                     GRIKFKLGGGNGGHNGLKDIQAKLGTADYYRLRLGIDHPGDRNLVVGYVLNKPSTEHR
                     RQIDDAVAKSLQAIPDILAGKWEEATRFLHSK"
     gene            32704..32910
                     /locus_tag="ACFOV4_000262"
     CDS             32704..32910
                     /locus_tag="ACFOV4_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dioxygenase"
                     /protein_id="HFC7618353.1"
                     /translation="MTELKQLIQTESIPVIEETLDFLLYECSIDDAPSAEEVAQWRDI
                     LAARGGKFLRLSKICQTWLDEEAA"
     gene            32907..33269
                     /locus_tag="ACFOV4_000263"
     CDS             32907..33269
                     /locus_tag="ACFOV4_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFC7618354.1"
                     /translation="MKLPRNRFSLLSALWFAGGIYSLLFKAADTAPPPFPHFDKAAHL
                     ALFFAQIWLLTKAFKTGKLPIPYRSLMVFALCFALFSECAQAWFTATRTGSLGDVLAD
                     MAGTVLALFAARAADRPD"
     gene            33500..34915
                     /locus_tag="ACFOV4_000264"
     CDS             33500..34915
                     /locus_tag="ACFOV4_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFC7618355.1"
                     /translation="MNLHAKDKTQHPENVELLSAQKPITDFKGLLTTIISAVVCFGIY
                     HILPYSPDANKGIALLIFVAALWFTEAVHITVTALMVPILAVVLGFPDMDIKKAMADF
                     SNPIIYIFFGGFALATALHMQRLDRKIAVSLLRLSRGNMKVAVLMLFLVTAFLSMWIS
                     NTATAAMMLPLAMGMLSHLDQEKEHKTYVFLLLGIAYCASIGGLGTLVGSPPNLIAAK
                     ALNLDFVGWMKLGLPMMLLILPLMLLSLYVILKPNLNERVEIKAESIPWTLHRVIALL
                     IFLATAAAWIFSSKIKTAFGISNPDTVIALSAAVAVVVFGVAQWKEVARNTDWGVLML
                     FGGGISLSTLLKTSGASEALGQQVAATFSGAPAFLVILIVAAFIIFLTEFTSNTASAA
                     LLVPIFSGIAMQMGLPEQVLVFVIGIGASCAFMLPVATPPNAIVFGTGLIKQREMMNV
                     GILLNILCVVLVALWAYAVLM"
     gene            35034..35543
                     /locus_tag="ACFOV4_000265"
     CDS             35034..35543
                     /locus_tag="ACFOV4_000265"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC7618356.1"
                     /translation="MIILHTNKGDIKIELDFDKAPVTAKNFEQYVKNGFYDGVIFHRV
                     IKGFMIQGGGMDENMNEKETRDPIQNEASNGLPNDKYTIAMARTSDPHSASAQFFINT
                     ADNAFLNFRSKELYGKTVVQDWGYAVFGKVVDGFDVVDAIEGVSTKRHGYHDDVPSEP
                     VVIIKAEAV"
     gene            35710..37092
                     /locus_tag="ACFOV4_000266"
     CDS             35710..37092
                     /locus_tag="ACFOV4_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFC7618357.1"
                     /translation="MASIARDIFKAYDIRGIVGKTLTDEAAYLIGKAIAAKAAEKGIT
                     RIALGRDGRLSGPELMEHIRRGFTDSGINVLNVGMVATPMLYFAAVNECGGSGVMITG
                     SHNPPDYNGFKMMLGGDTLAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYLKHI
                     TGHIRLKRPMNIAIDAGNGVGGAFAGKLYKGLGNEVTELFCDVDGTFPNHHPDPSKPK
                     NLQDLIAALKNGDAEIGLAFDGDADRLGVVTKDGNIIYPDRQLMLFAQDVLSRNPKAK
                     VIFDVKSTRLLAPWIKEHGGEPVMEKTGHSFIKSAMKKTGAPVAGEMSGHIFFKERWF
                     GFDDGLYAGARLLEILSASDNPSEVLNNLPQSISTPELNIALPEGSNGHQVIDELAAK
                     AEFEGATEIITIDGLRVEFPDGFGLMRASNTTPILVLRFEADTQEAIERIQNQFKAVI
                     ESNPNLIWPL"
     gene            complement(37112..37867)
                     /locus_tag="ACFOV4_000267"
     CDS             complement(37112..37867)
                     /locus_tag="ACFOV4_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFC7618358.1"
                     /translation="MIKIRNIHKTFGENTILRGINLDVCKGQVVVILGPSGSGKTTFL
                     RCLNALEMPEDGQIEFDNERPLKIDFSKKPSKHDILALRRKSGMVFQQYNLFPHKTAL
                     ENVMEGPVAVQGKPAAQAREEALKLLEKVGLGDKVDLYPYQLSGGQQQRVGIARALAI
                     QPELMLFDEPTSALDPELVQDVLNAMKELAREGWTMVVVTHEIKFALEVATTVVVMDG
                     GVIVEQGSPKELFDHPKHERTRRFLSQIQSTKI"
     gene            complement(37877..38593)
                     /locus_tag="ACFOV4_000268"
     CDS             complement(37877..38593)
                     /locus_tag="ACFOV4_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFC7618359.1"
                     /translation="MFNNFLASLPFMTETRADMIVSAFLPMVKAGFAVSLPLAAASFV
                     IGMMIAVAVALVRIMPAGGIVRKILLKLVEFYISVIRGTPLLVQLVIVFYGLPSVGIY
                     IDPIPAAIIGFSLNVGAYASETIRAAILSVPKGQWEAGFSIGMTYMQTFRRIVAPQAF
                     RVAVPPLSNEFIGLFKNTSLAAVVTVTELFRVAQETANRTYDFLPVYIEAALVYWCFC
                     KVLFLIQARLEKRFDRYVAK"
     gene            complement(38583..39410)
                     /locus_tag="ACFOV4_000269"
     CDS             complement(38583..39410)
                     /locus_tag="ACFOV4_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7618360.1"
                     /translation="MMLKKFVLGGIAALVLAACGGSESGSGASSAPAQSAVSGSLIER
                     INNKGTVTVGTEGTYAPFTYHDKDGKLTGYDVEVTRAVAEKLGVKVEFKETQWDSMMA
                     GLKAGRFDVVANQVGLTSPERQATFDKSDPYSWSGAVLVARNDSNIKSIDDIKGVKTA
                     QSLTSNYGEKAKAAGADLVAVDGLAQSLTLIEQKRADATLNDELAVLDYLKKNPNAGV
                     KIVWSAPADEKVGSGLIVNKGNDEAVAKFSTAINELKADGTLKKLGEQFFGKDISVQ"
     gene            39695..40603
                     /locus_tag="ACFOV4_000270"
     CDS             39695..40603
                     /locus_tag="ACFOV4_000270"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
                     /protein_id="HFC7618361.1"
                     /translation="MNTPQSAIIPDHAQAGIFIEADFAANRLNDIKAACRASLDALSA
                     LKTRFPDDILGLTIAFGSKAWATFGHTDEGSEIKPFSEMGNGLAPSTQHDMSIHIQSF
                     RQNTAYALAQSVLGAFGDSICVASEEHGLRLYQDRGLDGFVDGTENPQGDENVREVAI
                     IPEGKPDAGGSYVLLQKYLHDLKKWDAVPVAEQEASVGRGKETDDEFGRDVRLPDSHL
                     GRVNLKENGVGLKIVRRSLPFGKISGEHGLMFTAYCRTLHNIEAQLLSMFGDTDGKTD
                     LLLQHLSAAVSGGYYYAPSVERLQNL"
     gene            40836..44450
                     /gene="recB"
                     /locus_tag="ACFOV4_000271"
     CDS             40836..44450
                     /gene="recB"
                     /locus_tag="ACFOV4_000271"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HFC7618362.1"
                     /translation="MSAPIQAFDSLTVPIAGTNLIEASAGTGKTYGIAALFTRLIVLE
                     QKNVERVLVVTFTKAATAELKTRLRARLDDVLQVLESKEIAELGDGALSDGIAAYCAE
                     HHKGDTFLPALLKQALQKEGRTRLIVRLKAAIGQFDNAAIYTIHGFCQRILRDYAFLC
                     QAPFDVELTEEDGDRLLIPAQDFWRERVSNDPVLAALAFKRKAVPQTVLAQIRAYLSR
                     PYLNFRRPQADLKQAQRNAETSWQTVCRLLPELEAGFWRIHPDLNGNSYRKNSFGNLF
                     KELAQKSAAGQLPFLDKDTHDRLLKLASDKLEAGLKKGKTPDAAVFAELQKLADFGRD
                     LNALEEAEEATMIRLQLDLIEYLNRSLAEMKKSRRERGFDDLLLDVHTALTDNPHAET
                     LARAVAENWETALIDEFQDTDPLQYEIFQKIFIAQNRPLFLVGDPKQAIYSFRGADIY
                     AYLQAAEDARHRYTLATNYRSHAALIGSIGALFRLKERPFVLENIGYSEVGAARAESR
                     LSPKRPAVQVRWLHENDNEKANKDVLRRRAADYCADEIAHALNEAAECRLNFKGCPLQ
                     SGDIAVLVRTHNEAVMVSAALKKRQVQSVLLSRESVFASPEAAALSALIGFWLEPHRA
                     GTLRFVLTSGIFGYDAQQLHDFNQNESEILHWAESARTALDNWNQYGIFAAMQQFSQT
                     HGIETRLLSRNNGRSLTNYFQLLELLAAEDAQNRNPAALHKWLRDQISLAGNNGGDNR
                     AIRLESDEDLVKIVTMHASKGLQYPLVYCPFAWDAQDTGPSDWQILHQSANRTELLAK
                     AQLSEDEQKQYADEEMAERLRLLYVALTRAEEQLNIYAAYSTNTADNPLAYLIEGSPQ
                     DSRETVRRAYACEKDGIAMLKRNWRRVADNAPSGTNFAFTEDAPPPAAYRGNAGQTAE
                     FAANSIPERRFRFVRHTSFTALSRHTQTPDGGEEDACPSLDAAEISVAAMPSETPTAS
                     DGISIHNFPKGTQAGLCLHEILEDFKFGQAAAGQETLITDKLKKYGFEEIWLPAVAEM
                     AEACRKTPLTGAYGLSDIPPECRCPEMGFTLHTEDFGLKRLRDWFARDDIRLPEVCRA
                     AAETLDFHTVNGFLNGFIDMVCQDPEGNICVIDYKSNHLGADASAYTRQAMDEAVAHH
                     HYYLQALIYAVAAARYFKLRGQPPAAVSVRYLFLRGLDGKGGGVWRWDIDAAALEQIK
                     "
     gene            44489..44848
                     /locus_tag="ACFOV4_000272"
     CDS             44489..44848
                     /locus_tag="ACFOV4_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFC7618363.1"
                     /translation="MNIKHLITTALIASAAFAAQAAPQKPLSAAQTAQHPVVWIDVRS
                     EQEFSEGHLHNAVNIPVDQIVRRIHEAAPDKDTPVNLYCRSGRRAEAALQELKKAGYT
                     NVANHGGYEDLLKKGMK"
     gene            44973..45452
                     /locus_tag="ACFOV4_000273"
     CDS             44973..45452
                     /locus_tag="ACFOV4_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF302 domain-containing protein"
                     /protein_id="HFC7618364.1"
                     /translation="MKHILPLIAASALCISTASAHPASEPQTQNETAMTTHTLTSKYS
                     FDETVSRLETAIKSKGMDIFAVIDHQEAARRNGLTMQPAKVIVFGTPKAGTPLMVKDP
                     AFALQLPLRVLVTKTDGKVRAAYTDTRALIAGSRIGFDEVANTLANAEKLIQKTVGE"
     gene            complement(45728..47107)
                     /gene="radA"
                     /locus_tag="ACFOV4_000274"
     CDS             complement(45728..47107)
                     /gene="radA"
                     /locus_tag="ACFOV4_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFC7618365.1"
                     /translation="MAKTLKTLYQCTECGGTSPKWQGKCPHCGEWNTLQESLAAPEPK
                     NARFQSWAADTSTVQSLSTVTATEVPRNPTGMGELDRVLGGGLVDGAVILLGGDPGIG
                     KSTLLLQTIAKMAQSRKVLYVSGEESAQQVALRAQRLELPTEGVNLLAEIRMEAIQAA
                     LKQHQPEVVVIDSIQTMYSDQITSAPGSVSQVRECAAQLTRMAKQMGIAMILVGHVTK
                     DGAIAGPRVLEHMVDTVLYFEGDQHSNYRMIRAIKNRFGAANELGVFAMTENGLKGVS
                     NPSAIFLASYRDDTPGSCVLVTQEGSRPLLVEIQALVDDAHGFTPKRLTVGLEQNRLA
                     MLLAVLNRHGGIACFDQDVFLNAVGGVKIGEPAADLAVILAMLSSFRNRPLPEKMVAF
                     GEIGLSGEVRPVARGQERLKEAEKLGFKRAIVPKANMPRNAKEFPNLKIYGVSSLQEA
                     IDICRDSRE"
     gene            47135..47296
                     /locus_tag="ACFOV4_000275"
     CDS             47135..47296
                     /locus_tag="ACFOV4_000275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618366.1"
                     /translation="MPSEIGTVGITPIRQHRRRHVLSIHGGYCRIALFFHPSASDGIS
                     GGFLPAYPP"
     gene            complement(47284..48348)
                     /gene="hemE"
                     /locus_tag="ACFOV4_000276"
     CDS             complement(47284..48348)
                     /gene="hemE"
                     /locus_tag="ACFOV4_000276"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HFC7618367.1"
                     /translation="MTLLKNDTFLRALLKQPVEYTPIWMMRQAGRYLPEYKATRAKAG
                     SFLDLCKNTGLATEVTIQPLERFDLDAAILFSDILTVPDAMGLGLYFAEGEGPKFKRA
                     LQHEADIAKLHVPDMEKLQYVFDAVSSIRKALDGRVPLIGFSGSPFTLACYMVEGGGS
                     KEFRTIKTMMYSRPDLLHKILDTNAQAVTAYLNAQIDAGAQAVQIFDTWGGVLSDAAF
                     KEFSLKYIRQIVAGLKRESEGRRVPVIVFAKGGGLWLESMAQIGADALGLDWTCNIGE
                     ARRRVGKQVALQGNFDPFALFGTPESIRTEVARILADYGHGSGHVFNLGHGINQHADP
                     EHAKILVDTVHELSRQYHGG"
     gene            complement(48423..49640)
                     /locus_tag="ACFOV4_000277"
     CDS             complement(48423..49640)
                     /locus_tag="ACFOV4_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme biosynthesis protein HemY"
                     /protein_id="HFC7618368.1"
                     /translation="MKTVVWIVVLFAAAVGLALASGIYTGDVYIVLGQTMLRINLHAF
                     VLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKGRKAALALNKAGLAYFEGRFEK
                     AELEASRVLVNKEAGDNRTLALMLGAHAAGQMENIELRDRYLAEIAKLPEKQQLSRYL
                     LLAESALNRRDYEAAEANLHAAAKMNANLTRLVRLQLRYAFDRGDALQVLAKTEKLSK
                     AGALGKSEMERYQNWAYRRQLADAADAAALKTCLKRIPDSLKNGELSVSVAEKYERLG
                     LYADAVKWVKQHYPHNRRPELLEAFVESVRFLGEREQQKAIDFADAWLKEQPDNALLL
                     MYLGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQRNLVLA
                     SVAEENRPSAETH"
     gene            complement(49637..50911)
                     /locus_tag="ACFOV4_000278"
     CDS             complement(49637..50911)
                     /locus_tag="ACFOV4_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HFC7618369.1"
                     /translation="MPSETSSPRKENETEVHIPAAPFIVKQSGNNALATCALVLAALG
                     LGASGFLFVQGQNVLKNQELAFNQKIDKAALGESENAALLKDNLNRQAAIQSELDRLD
                     GNVKANGEQILEMQKSYRELTKGRADWLVDETETILNLAAQQLVLTGNIQTAVGVLEH
                     IDSRLSRFNQAELLPIKQAVSSDLAELKNRPYVDISGTALRLDRLETAVSGLPLILDG
                     VLKPGVQVKNEAASASWWQNVWEKSLGTLKGLVEIRRLENNDAMLISPEQAYFVRENL
                     RLRLLDARTALMQRNSEVYQGDLNNAEAAVRQYFDAKSPATQSWLKELAELKALDVRM
                     TADDGLKNSLNAVRAYRDGTRMTAAENQEAEQAASEPANENTASEPAAASDVKTIEAP
                     SLPSERKPEQPAKKQPVPEKAGRSPSAKGERA"
     gene            complement(50986..51747)
                     /locus_tag="ACFOV4_000279"
     CDS             complement(50986..51747)
                     /locus_tag="ACFOV4_000279"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HFC7618370.1"
                     /translation="METAKPVMLIVRPSGRAAEDVETCLNAGWRAEVLSPVEIEADAA
                     GLELLSEQYARADAVFWVSPTAVETAVPYLNLSDGIKAQIAVGQGSRRALERCLVRTV
                     IAPDDGNDSEAVLRLPVWNSLPEGARVLFVCGHGGRDFLMNALQEKGFRTEVAEVYFR
                     RHKPLNFQNFQTENIAAAYITSTELVRLLFGQLPPQFSRFFKSLLYFTHHPRIAEALK
                     REGVCSVETVPTLEAALSHSSISVSDGMVFPGTSN"
     gene            complement(51768..52187)
                     /locus_tag="ACFOV4_000280"
     CDS             complement(51768..52187)
                     /locus_tag="ACFOV4_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein Gly1ORF1"
                     /protein_id="HFC7618371.1"
                     /translation="MKKMFLSAVLLLSAATRTVWADTVFSCKTDNNKYIEVQKINRNL
                     YEYSFGSAAKKEIAIRNSKADLLGRSDRWQGMGSGRWATMKFQNGEFMYTIWTGFDSV
                     THTESSGVVVERRGKEVARVGCTPKTAQANFNDDDFS"
     gene            complement(52438..52758)
                     /locus_tag="ACFOV4_000281"
     CDS             complement(52438..52758)
                     /locus_tag="ACFOV4_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2322 family protein"
                     /protein_id="HFC7618372.1"
                     /translation="MNFQDYLATFSSIDHLGGLDVQDADGKTVHHIPAVQGKLGSLKL
                     YNALAERFDGKLDKEAAEQGLIWFAEHVADARAHPGKHPNIDLLEKVVQSGETLLLKP
                     LAAQ"
     gene            complement(52781..53407)
                     /gene="upp"
                     /locus_tag="ACFOV4_000282"
     CDS             complement(52781..53407)
                     /gene="upp"
                     /locus_tag="ACFOV4_000282"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006223 - uracil salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFC7618373.1"
                     /translation="MNVNVINHPLVRHKLTLMREADCSTYKFRTLAIELARLMAYEAS
                     RDFEIEKYLIDGWCGQIEGDRIKGKTLTVVPILRAGLGMLDGVLDLIPTAKISVVGLQ
                     RDEETLKPVSYFEKFVDSMDERPALIIDPMLATGGSMVATIDLLKAKGCKNIKALVLV
                     AAPEGVKAVNDAHPDVTIYTAALDSHLNENGYIIPGLGDAGDKIFGTR"
     gene            complement(53513..53824)
                     /gene="grxD"
                     /locus_tag="ACFOV4_000283"
     CDS             complement(53513..53824)
                     /gene="grxD"
                     /locus_tag="ACFOV4_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Grx4 family monothiol glutaredoxin"
                     /protein_id="HFC7618374.1"
                     /translation="MASIHDQIKEVVTTHRVVLFMKGTKQFPQCGFSSRAVQILNAAG
                     CTDYVTVNVLENPEVRQGIKEYSDWPTIPQLYVNGEFVGGSDILMEMYEAGELQELLK
                     A"
     gene            complement(53925..54139)
                     /locus_tag="ACFOV4_000284"
                     /pseudo
     CDS             complement(53925..54139)
                     /locus_tag="ACFOV4_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
     gene            complement(54165..54944)
                     /locus_tag="ACFOV4_000285"
     CDS             complement(54165..54944)
                     /locus_tag="ACFOV4_000285"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFC7618375.1"
                     /translation="MHIIDSHCHLNFEGLKERLPEVLSNMEANGVGQALAISVSRESF
                     AEVSAIAEVYEHIYCTIGVHPDSKEAEEFSIAEMVAAAASPKEVGIGETGLDYYWCKG
                     DLSWQHKRFADHIEAANQTGLPVIVHTRDAAADTLSILKECRVNSGVIHCFSEDIGFA
                     RAAMDLGLYISFSGIVTFKNAPLVQEAAKYVPDDRILVETDAPFLAPVPKRGRQNEPA
                     FVRHTAEHIAKLRNQTLEQVAAYTTENFYRLFKKVPDMRTV"
     gene            complement(54949..55299)
                     /locus_tag="ACFOV4_000286"
     CDS             complement(54949..55299)
                     /locus_tag="ACFOV4_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HFC7618376.1"
                     /translation="MSDGQNIPAKMMSLQLKDMNLLYSSYMPFLEHGGLFVQTNDVFS
                     IGDDILLAVEILNFPKLFLPTKVAWINPARTSSKPKGVGLAFTKHENCLKVKDQIEVE
                     LGNTIGGSRPTFTM"
     gene            complement(55303..56280)
                     /locus_tag="ACFOV4_000287"
     CDS             complement(55303..56280)
                     /locus_tag="ACFOV4_000287"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFC7618377.1"
                     /translation="MIYPWHNEQWRQIAEHWERRPNAWLFAGKKDTGKTTFARFAAKA
                     LLCETPAPGCKPCGECMSCHLFGQGSHPDFYEITPLSDEPENGRKLLQIKIDAVREII
                     DNVYLTSVRGGLRVILIHPAESMNVQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTI
                     KSRCRKMVLPAPSHEEALAYLRERGVAEPEERLAFHSGAPLFDEADGVRALRIKLLDI
                     LAEPRLLKILDYAALFDKEKLPLDVFVGWMQKWLVDLGLCLQHMKPVYYPAYEDRLLQ
                     TASGFRLRNVFAAEDMLKQLAPYGFHTLNVKMQIEHLLINYLELKKENG"
     gene            complement(56314..57444)
                     /locus_tag="ACFOV4_000288"
     CDS             complement(56314..57444)
                     /locus_tag="ACFOV4_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="HFC7618378.1"
                     /translation="MFTDENMTAKEELFAWLRHMNKNKGSDLFVTTHFPPAMKLDGKI
                     TRITDEPLTAEKCMEIAFSIMSAKQAEEFSSTNECNFAISLPDTSRFRVNAMIQRGAT
                     ALVFRAITSKIPKFESLNLPPVLKDVALKKRGLVIFVGGTGSGKSTSLASLIDYRNEN
                     SFGHIITIEDPIEFVHEHKNCIITQREVGVDTENWMAALKNTLRQAPDVILIGEIRDR
                     ETMDYAIAFAETGHLCMATLHANSTNQALDRIINFFPEERREQLLTDLSLNLQAFISQ
                     RLVPRDGGKGRVAAVEVLLNSPLISELIHNGNIHEIKEVMKKSTTLGMQTFDQHLYQL
                     YEKGDISLQEALKNADSAHDLRLAVQLRSRRAQSSSPDLELL"
     gene            57612..58313
                     /locus_tag="ACFOV4_000289"
     CDS             57612..58313
                     /locus_tag="ACFOV4_000289"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFC7618379.1"
                     /translation="MSLKTVAVIGAMEQEIKLLREMMENIKAVSFGRFSAYEGELVGK
                     RMVLALSGIGKVNAAVATAWLIHQFAPDCVINTGSAGGLGKGLKVGDVVIGTETAHHD
                     VDVTAFGYVWGQVPQLPARFASDGILIEAAKRAARTFEGAAVEQGLIVSGDRFVHSSE
                     GVAEIRKHFPEVKAVEMEAAAIAQTCHQLETPFVIIRAVSDSADEKADISFDEFLKTA
                     AANSAKMVAEIVKSL"
     gene            58455..60248
                     /gene="lepA"
                     /locus_tag="ACFOV4_000290"
     CDS             58455..60248
                     /gene="lepA"
                     /locus_tag="ACFOV4_000290"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFC7618380.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLADRFIQYCGGLDLREMSTQVLDSM
                     DIEKERGITIKAQTAALNYKARDGQVYQLNLIDTPGHVDFSYEVSRSLSACEGALLVV
                     DASQGVEAQTVANCYTAIDLGVEVVPVLNKIDLPAADPERVEQEIEDIIGIDAVGAVQ
                     CSAKSGIDVEDVLEEIVAKIPAPTGDENAPLQAVIVDSWFDNYVGVVMLIRVKNGTIK
                     LKDKVRFMSTKAETQVEQLGVFTPKSVQKQELKAGEVGFLITGVKELGQAKVGDTVTL
                     VANPATEPLPGFQEVQSQVFAGLYPVESHDYEALRDALEKLQLNDASLKFEPEVSQAL
                     GFGFRCGFLGLLHLEIVQERLEREFDMDLITTAPTVVYEVVLKNGEKIEVENPSKLPD
                     IGSIETILEPIITATILVPQEYVGNVMTLCNQKRGVQVNMQYMGRQVMLTYDLPMNEV
                     VMDFFDKLKSTSRGYASLDYHFKEFQPSDLIKLDIMVNGEKVDALSLIVHRQSAVHRG
                     RELASKMRELIPRQMFDIAVQAAIGSQIIARENVKALRKNVLAKCYGGDITRKKKLLE
                     KQKAGKRRMKQVGNVEIPQSAFLAILQVSDK"
     gene            60393..61412
                     /gene="lepB"
                     /locus_tag="ACFOV4_000291"
     CDS             60393..61412
                     /gene="lepB"
                     /locus_tag="ACFOV4_000291"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFC7618381.1"
                     /translation="MNTMLMSGAAAALLAGIILYFKSDKKRQENGEWSSGLEYAYILT
                     AVGVFAALSLFMSFAAVFLIFVVLCGTAWAVYKYRLKTHPEISESSHFGDYFGSFFPT
                     VLVLFLIRSFIAEPFQIPSSSMRPGLIKGDFILVGKFSYGLRVPVLNNIFIPTGKIER
                     GDVVVFNYPLQPEMTYIKRIVGIPGDVVEYRDKILTVNGKPTSDIPNGTYRYPDDTDP
                     SEIHNTDMFRSDLDGKSFNILKKEGQPAVSLPVLGKYTSDIMSENGYSIEQSGLEHCQ
                     YADDGSGFVCKVPEGRYFAMGDNRDNSADSRYWGFVDDKLVVGKAMFILMNFGDFGRS
                     GTAIR"
     gene            complement(61533..61676)
                     /locus_tag="ACFOV4_000292"
     CDS             complement(61533..61676)
                     /locus_tag="ACFOV4_000292"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618382.1"
                     /translation="MPSEALSDGIGAGRIKKAASAAAHTVSRTKCPLFNGMGFHTNGN
                     IVD"
     gene            complement(61785..62690)
                     /locus_tag="ACFOV4_000293"
     CDS             complement(61785..62690)
                     /locus_tag="ACFOV4_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFC7618383.1"
                     /translation="MGKGGDIVVGNGKKYAAPLLVLGCVVFGLGSLIVRSVPVGPYAI
                     AFWRLLISVFVFWFLARFFGQKFPKNRKTVRYALTAGVFLAFDLALWHESIHAVGPGI
                     STLLNSLQIFFLSAIGVFFFNERLSGLKKAGLISAVAGVAMIAGAEFGYNGNAVWGFA
                     SGLVSGLMLALSMVFVRKTHEIEPVALFPSMMILSLGGAVSLVVPALLMDGGVLYPTT
                     WKDAGLVLVYGVVMQCFAWAMVAYAIPLLSLSLTGLLLLSEPVAALFIDYFGLGKPIE
                     GVQWAGVALTLSAIYLGSLKQQSEP"
BASE COUNT        14938 a        17357 c        15745 g        14965 t
ORIGIN      
        1 ttttattaac gcatgctctc ctatggttgc cgttgtcgac atcattattg atttagcagg
       61 aaacagcttg ccgcccttaa ctgcgctttt tgatatatgc ttcaatgaat tatctaaaat
      121 acggccattt tccctaatat cttccattct aaaccaaggg attgagccat tttcccaata
      181 ttctttattt gatttggaag gggtatagcc attcttcaag tcaaacacct cccccaacgt
      241 cttccaaacc acatctttca gacggccttt atagccatca gctatccccc cccgatttga
      301 ttgtcaaaat ctaaaagaaa gtcgcggtaa taccggtatt ggcgtttgcg cagggctaat
      361 tcagcttcca gctcggtgaa tttgtcaagt atttttacaa tttttttgtt gggtttccag
      421 gggtgggata gggattaata attttttcaa gttactggca tttagagcag gaatacctgt
      481 aaatgtacat aaggcatgaa tctcttgttc aaattcaagt aatatatgat agagaaaacg
      541 aacatccaat tctgttctat tcttaatagt aactgcataa tttaagttgc cacgaaaata
      601 tcttccttct tgccacgtta ttgagccgac tcccgctcct cttgttgtga tgccgatagg
      661 gtcattttca gtgttccatt catcaatata gccaagcggc tctttgccac tgttaataac
      721 tggataacta ccaatattat ttgagatttt ctgcttactt acagcttgtc ctgtttttat
      781 gatagctatc ccattttctc cacccaacgg cttccactcc accggtgccg tctgaatcat
      841 ctcaatcaat tttttcgctt tgctttgcat atccatggtt gttttccgtt tctttcccgc
      901 tgtggcggga tgtggggcgg ttgtggggtg cttcggctca ctctgtccgt ttgccgttat
      961 ttctgcgggc tgaagtccgt cctgctttca ggctgcctgc aatggtgtgc aggctgcttt
     1021 ttcaggtagc ctgaatggta gttattttgt gcggtctttt ttctgtttga tctgttgcac
     1081 ggctgttttt tccaacgctt taacgctttc cagataggct tgctccaccg gcgacaggat
     1141 gcgcgcttca taggcgcggt attcgcgttc ggctttctgc tctgcctgtt tgcggctgat
     1201 gctgcctgca ccctgtaatg tgccttgtcc gtacagcccg gaaaatttgt ccaattcggc
     1261 tatccagtcg cgcatataca tggggctttg ctcctgcgct ttgatttccg ctaggtcgaa
     1321 gaaggcggaa accaaacggt tcaggcggaa cagttcgtct tcggtcagat agtttttggc
     1381 gattttggct tcattcagcg tggggattgc gccttgaaag gtggtcagcc ccataaagtc
     1441 tttgctgctg tcggcacggc tgtatatcag ctcagctgcg gtttgccggc tggcggcata
     1501 gtgcagtttg ttttgaacgg cggcaaaaaa ggtttggctt tcgctgcttt tggggttgta
     1561 gtcttggctg gtggcatata aatcaagcac ttgccggtat agggcttttt cgctgctgcg
     1621 gatgtcgcga atgcggttga gcagttcttt ccaatagtcg ccgccgcctg tgcctttcag
     1681 gcgttcgtcg tctatggcaa agcctttggt cagatattcg tccagccgtt cggttgccca
     1741 ttggcggaat tggatgcccc gcgcggaacg gacgcggtag ccgacggcaa taatcatggg
     1801 cagggaataa tgggcgattt tgcggtttac cttgcgcccg ttttcatttt gaactgtcaa
     1861 ctggaagttg acagttgcct tctcttccaa ttcttgctct gcaagaatgg ttttaatgtg
     1921 tttgctgata ttttgtttgg tggtttggta cagttctgcc atgtccgcct gcgtcagcca
     1981 aagctgtccg ccaaattcct gcaaggcaaa ttgggcagtg ccgtcgttgg cggtgtatag
     2041 gatgatgctc atgcttcaat ctctgcaatc acttcgtcaa tttcacgccg cagccgttcg
     2101 attttggcaa cggtttcgct gatttcggcg ttaagctgtt tgatgtcgat aatttcgcgg
     2161 gtgtcttcgg gttcaacata gctgctgacg gcgaggttgt agccgttgtc tttgacggtt
     2221 tgctgggcgg cgttttgggc gatatgcggc acatcggctt tatcggcgaa gagtttgacg
     2281 atttcggcaa tgtgttcttc ggttaagacg ttgttgttgg tttctttttt aaagaagccg
     2341 cctgcgtcga tgaattggat gtcggtattg tctttgtgtt tggacaaaac cagtatattg
     2401 acggcgatgc cggtgccgta aaagagattg ggcgcaaggg cgatgacggt ttccacgtag
     2461 ttgccctcca ccagatattg gcggattttc tgctctgcgc cgccgcgata gaaaatgccg
     2521 gggaatgaga cgatggcggc gcggcctctg ccggaaaggt agttcagtgc gtgcagaatg
     2581 aaggcaaaat cggctttgga tttcggggcg agtacgcctg caggggcaaa gcggtcgtcg
     2641 ttgattaagg tggggtcgcc gctgcctatc cagttgatgg aatagggcgg attggaaacg
     2701 acggcatcaa agggtttgct gtctttgagt ttgggattgg tcagtgtgtc gcccaattcg
     2761 atgtggaatt tgttgtaatt gacgttgtgc agaaacatat tcatgcgggc gaggttgtag
     2821 gtggtgtggt tgatttcctg cccgaagaag ccttcttcga tgatgtgctc gtcaaactgt
     2881 tttttcgcct gcaagagcag gctgcccgag ccgcaagctg ggtcgtagat tttgtttact
     2941 ttctcctgcc cgtgcaccgc cagccgcgca atcagcttgg atacgctttg cggggtgaaa
     3001 aattcgccgc cggatttgcc tgcgttggca gcgtagttgg aaatcaggta ttcgtaggca
     3061 tcgccgaaaa ggtcgatgtg gtggtcttca aaactgccga aatcgagttc cgccacgcct
     3121 tttaggacgg cggcaaggcg tttgttcttg tcggcaacgg tgctgccgag ccggctgctg
     3181 gtggtgtcga agtcgtcaaa caggccttta atgtcttgtt cggacggata gccggaggcg
     3241 gagctttcaa tcgcggtaaa aatttctttc agcttggtgt tgagctcttc gttttgatgg
     3301 gcttcggcgg caatattgca aaaaagctgg ccggggtaga tgaaatagcc tttgactttg
     3361 acggcatcgt ctttgatttc gggcgtgatg atgctgtccg gcatagcggc gtaatcaata
     3421 ctgctgtcgc ctgcctgcat atagtcggta aagttttcgc tgataaagcg gtagaaaagt
     3481 gtgccgagaa cgtattgttt aaagtcccag ccgtccaccg cgccgcgtac ttcgtcggca
     3541 attttccaaa tttggcggtg cagttgggcg cgttgttgca tttcggtcat catcgaaatc
     3601 catataaaag ttaaacaaat cgaaatcgcc tgatattttc agacgatttt ttacgggcat
     3661 tcaaattaag ccaaattttc cagcatccat ttgacgtagc gctcgacgcc tgatttgaca
     3721 tcgaaaaatt cttccgtata acctgcctca cgcaatttgg tgatgtcggc ttgagtgaag
     3781 ctttggtatt tgcctttgag cgcatcggga aatgggatgt agcggataag ttcttcttct
     3841 accagctctt tcaagctcat ttcgggtttg ccttcggcgg cgcggcaggc gttgacggtg
     3901 gcggcggcga gttcgttgaa ctgttggctg cggccggtgc cgaggttgta gatgccggaa
     3961 agttcgggat ggtcgaagaa gtagaggttg actttggcaa cgtcttcgac gctgacaaag
     4021 tcgcgggttt gttcgccgtt gccgtagccg tcgttgctgc cgaacaggtt gacgtaaccg
     4081 tgttcgcggt attggtggaa atggtggaag gcgacggatg ccatacggcc tttgtgttgt
     4141 tcgtgttgtc cgtacacgtt gaagtagcgg aagccgacga cttgggcggt caagccttct
     4201 ttcatgcggc ggcgcaatac ttggtcaaac aggaatttgg aatagccgta cacattgagc
     4261 ggtttttcga gttcgcgctc ttcacggaag atttcgcctt taccatacac ggcggcactg
     4321 gaggcataaa ggaagggaat gcgttcgtcc tgacaccagt ccaacaaatc cagcgtgtac
     4381 tggtagttgt tttccatcat atacaaaccg tcgtgattca tggtgtcgga acacgcgcct
     4441 tgatggaaaa cggcttcgat gttttgataa ggtaaaatgt gttccctcac ttggcggatg
     4501 aattcatgtt tgtcgagata atgggcgatt tcgcactcgg caaggttttt gaatttttcg
     4561 cctttgctca aattatcgac ggcaacaatg tcagtaatac cgcgttgatt aagtgctttg
     4621 acgatgttgc tgccgataaa gccggccgcg cctgttacga tgatggtcat attcggtttc
     4681 ctttgttttg agtaaaatta ataaacttag ttacaagaaa tcatcgatat tgtcctgaaa
     4741 cacaaatttg cgatgatatt ccaaatattt ttctcttcct tcgggatata ttctcatctt
     4801 aattttttgc atttggattg atattaagtt tttcccatgt gtaacggctt agtcgagtac
     4861 cgcaaatcaa acgaccatca tccaagaaag taatataacc ttgatcgaac aaccaatcat
     4921 aagtcggcgt taaagctaac ccatttaaat aatctaatgc ctctttctca tttttctcag
     4981 taatacaaac catataaggt ttaatatgac tagcccttaa caaaatctca tctgtaatta
     5041 atgtaaatgg acattgcggc atatgattta taacatcctt gcgatatttc tgctgccctt
     5101 ttctactttt ctgtttaatg atttcttgct ctacgaattg attaaattct gaagccggta
     5161 tttctaattt ttctcttgat aagagttgcg ggtgcacgat agagcgaaat tgataatcca
     5221 aaaatattcg gaaataaaat aatggttctg aatcttctat atctttgaca ggcaatagtt
     5281 taagaattga taaataacta attttgggca atacaatctt acgccaaatt gaccatatat
     5341 catcctccga acggatataa cccctacggt aacctttaga attttccaaa tggtctgata
     5401 catcatggat tgaaaagaaa atattttctg taggcagatt attaatactt aaaacgtaat
     5461 catcataaaa ccttgaaata tcatgatgat atttctgttc ttgtttgtga tattcaactt
     5521 ttgcatcaac caaataacgc tgtaaatttt tcttattaaa aaaacaattt ttctgaatga
     5581 aaggatattc taccctcctt ccattttttg tctcagtaat cccccaattt tcatactcaa
     5641 aaaatgtact tagttttcga ccactatcat caatataact acctacatat ttgcgtgctt
     5701 ccccattacc accaaaaaca gataacttgt tattcctgtg aataaaacta tcttccgcac
     5761 gtaaattttg aatactatcg acaataaaat actctatgtt ttcaatagta attctttgaa
     5821 aatccggcat tttactctcc ataaagcgta atatccattt gttttaatat agcgattaat
     5881 acatcaacaa caatactgtt tcccgcttgg cgatacattt gagtatcact aactaaaatt
     5941 ttaaaatcat ctctaaaacc cattagccgc aaacattccc taggtgttaa tttacgaata
     6001 cgtccacgat tatgagtaac ataattatca accccggcac gatgcatttt atgcatagtt
     6061 tgcaataatg ggcgagctac aggcaaatca gtttccgtac tggttttaaa attttttgtt
     6121 cctcctgcca aaacataatt tttgattttt tcagaaagat aatatttttc ctcaacgtta
     6181 tttacatcaa aaataaagtc atcaaattca gattcgcggg ctgcctgaaa aataaaatca
     6241 ccatgccaat taaattgttg atttgctttt tggcataagg caatttctcc attaatctgt
     6301 gtataacgtt tttgtctatt tttagaactg gtaacaaatt tcacaccctt ttcacgtaaa
     6361 aaatatttgc tatcagtata gtcctccaaa aaatcttgca tagtatgttc taattcaatc
     6421 ttttcaggaa actgaaaacc atttatagga ggggtatgaa agccaacaac aaaaatacgc
     6481 tcacgatgtt gaggaatccc ataatcctta ctattcatta tttggaaata taagtcataa
     6541 ccaagtgaat aaaaaacact ttttacaact ttccaagttt ttccattatc atgattgagc
     6601 aagcccttta cattttcata aataaatatc tttggttgga cttcatccac aacgcgagca
     6661 aattcataga ataatgttcc tcgtgtatct tctaatcctg cacgtttgcc aaccatggaa
     6721 aatgcttggc aaggactgcc tccaactaaa atatcaactt gatttctaaa ctttctcgca
     6781 tcaaattgag taatgtcgtt atgccaaaaa tcttcattta atttatagtt tccaagataa
     6841 ctttttttaa cgtatggatc aatatctcct gcaaaaacaa tggtatggtt taaatttaat
     6901 cggtggaatg cctgttcaac cgcaccaatc ccgctgaata cggttgctaa tctaatatgt
     6961 gaatcaggtt taagaaaagt tttagatttc caaccttgtt gactgggaaa gagcaaagtt
     7021 ttttgtaatc gagtatcgtg tgtctgtgcc attgtcgaaa tagtcatact tatatcgttc
     7081 tgtttatctt atcaatatga aaactacatt gttgattgcc ctgacaatgc cttgatcaat
     7141 tcggcaaacg agcaaaccgc cgtaccgagt ttcgccacga caaccccggc cgcagtattg
     7201 gcaaggtaca tggcttcggg catggtgcag cctgccgcca aacccaagcc cattccggca
     7261 atgacggtgt cgcccgcacc ggatacgtcg taaacttctt gggcgcgggt gggctggtaa
     7321 atcggttcgc cttcgctgaa caaggtcatg ccttcttcgc ttcgggtcag taaaacggcg
     7381 gtcaggtcga ggtggcggcg caggttttgc gctttttcgg tcagctcgct ttcgtttttc
     7441 caactgccga ccacttcttt caattcggcg cggttaggcg taatcagagt tgcaccgaca
     7501 tatttttcgt aatcgtcgcc tttggggtcg attaagacgg ttttgccggc gtgtttcgcc
     7561 caatcgatca tatcggagat atgcgacagg ccgcctttgc cgtagtctga aaaaatgatt
     7621 gcgtcgtatt cgggcaagat ttcgcggtat ttctgcttga tttgttccaa cacttcgcag
     7681 ttgggatgtt cttcaaaatc aagacggata agctgctggt tgcgggcgac gacgcgcagt
     7741 ttgacggtgg tggcgatttg tttgtcgcgc atcagatagg aggcgacgcc gtcctgcacc
     7801 atcagcgcat cgagcgcgtc ggcggcttcg tcgttgccgg ttacggacaa cagccctgcc
     7861 ctgccgccca acgaagcgat gttgcgcgcg acatttgccg ctccgcccgc gcgttggtcg
     7921 attcgtccga ttttcgccac cggcacgggg gcttcgggcg aaatacggga cacatcgccg
     7981 aaccaatagc ggtcgagcat cacgtcgccg acaaccagga ctttggcttg cgcgaaacgg
     8041 gatttgaggg tttcttgttg gaacttggcg gacatattgc ctccgttgta ttttttcaga
     8101 cggcctcagc ctgtaaggcc gtctgaaaat cagtttgctt caaggtttgc cacgcggttc
     8161 acttcgcgca atacggctac cggatcggca gcttgggtta caggacgacc cattaccaaa
     8221 taagtcgaag cggcagccaa ggcttcggcc ggtgtcatga tgcggcgctg gtcatcatta
     8281 ttgccggcaa cgtccaagcg gatgccgggc gtgaccaaga caaaatcttg tcccaactcg
     8341 cggcgcagcg gtgcggcttc ttgggcggaa cagaccacgc cgtccaagcc cgaactttgc
     8401 gccagttttg ccaagcggat gacttgttct tcaggggcgg tgttcaaacc gatttccgcc
     8461 aaatcgcttt gttccatgct ggtcaacacg gttacgccga ttaagagcgg ctttgtaccg
     8521 tatccggcaa cggcttctgc tgcggcttcc atcatacggc ggccgcccga tgcgtgcata
     8581 tcgaccatcc aaacgcccat atcggcagcg actttgcagg cttgcgcgac ggtgtgggga
     8641 atatcgtggt atttcaaatc gaggaaaagt ttgaaacctt gattgattaa gctttctgcc
     8701 aaattgcgtc ccgtcgcggt aaacagctct ttgccgattt tgatttgaca caatgtcggg
     8761 tcaaggttgc ggacgaatcc gagcgtgtct ttttcgttgg aaaaatcaag ggcgacgatg
     8821 acgggggtgc gttgttgcgg agtttggaag tcggagatta aaggattcat ggtgttttcg
     8881 tttcgggttt tcagacgacc tttatcgtct ttttcgcagt atagtggatt aactttaaac
     8941 cggtacggcg ttgtctcgcc ttagttcaaa gagaacgctt ctctaaggtg ctgaagcaca
     9001 aagtgaatcg gttccgtact gtttgtactg cctgcggctt cgtcgccttg tcctgatttt
     9061 tgttaatcca ctataacaac gtaaattcaa accgtaggtc gggcattgat gtccgaccta
     9121 cgcggactca agcctccgac aaactgtttc ggataaattt gaaccggtac atcagccgtc
     9181 attcccgcgc aggcgggaat ccattgataa aactcagttc atcagattta aacagcgatt
     9241 gcccaaattc agaaatggat tcccgcctgc gcgggaatga cgccaaatga ttatttttcg
     9301 gttgcaacac gctgtttatc aaaaacaggt cgtctgaaaa cctgattttc tgttttcaga
     9361 gtgcgaagcc tgcccgtggg tacgaccttt tcgatttatt tgcccaatgc gcccaatact
     9421 tcggctttca cggcttctac cggctgagtg ccgtcaactt tgatgtattt aggcgcgtgt
     9481 tcgccttcca gtttgctgta aaaatcgacc aaaacttcgg tttgctcgtg gtaaacggca
     9541 aggcgttttt tcacggtttc ttctttgtcg tcgtcgcgct gaatcaaatc ttcgccggtt
     9601 acgtcgtctt tgccttcaac tttgggcggg ttgtaggtaa cgtggtaagt acggccggaa
     9661 gccaaatgca cgcggcggcc gctcatgcgg tcgacaatca cgctgtcagg cacatcgatt
     9721 tcaacgactg catccaaatc cacgcctgct tcaaccatcg cttcggcttg tgccaatgtg
     9781 cgcgggaaac cgtcaaacag gaaaccgttt ttgcagtcgt cttgcgcgat gcgttctttg
     9841 accatgccga taatgatgtc gtcgcgcacc aagccgcctt cgtcaatgat ttttttcgct
     9901 tccaaaccca agggcgtgcc tgccttaatc gcggcacgga gcatgtcgcc ggtagagatt
     9961 tgcggaatgc cgaacgctgc ggtgatgaat tgcgcctgag tgcctttgcc cgcgcccggt
    10021 gcgcctaaaa gtaatgcttt catgaagtga tccttttaaa tgtgtttatt ggaatcaaac
    10081 agatggttta cgattctaca cggcttggca caatagttca aaaaccaact gcacaaactg
    10141 ccatttgcaa gcaaatgttt tgcatacctt tgccgagcct gatattcaca aggcggcaac
    10201 tttttgggac aatccccaaa atttcaaaac atcacaccct accaaaaagg aacatccgtg
    10261 aaacgcattt ttctgttttt ggctaccaat atcgctgttt tggtcgtaat caacattgtt
    10321 ttggcggttc tgggcatcaa cagccggggc ggcgcgggca gcctgttggc gtattccgcc
    10381 gtcgtcggct tcagcggctc gattatttcg ctgctgatgt ccaaattcat cgccaaacaa
    10441 tcggtcggtg cggaagtcat cgacacgccg cgcaccgaag aagaagcctg gcttttgaac
    10501 actgtcgaag cccaagcgcg gcaatggaac ctgaaaacgc ccgaagtcgc catctaccac
    10561 tcccccgaac ccaatgcctt tgccacgggc gcatcgagaa acagctccct gatcgccgtc
    10621 agcaccggtt tgctcgacca tatgacgcgt gacgaagtgg aagccgtatt ggcgcacgaa
    10681 atggcacacg tcggcaacgg cgatatggtt acgctgacgc tgattcaagg cgtggtcaat
    10741 acctttgtcg tgttcctgtc gcgcattatt gccaacctga ttgcccgaaa caacgacggc
    10801 agccagtccc agggaactta tttcctggtc agcatggtat tccaaatcct gttcggcttc
    10861 cttgccagct taattgtcat gtggttcagc cgacaacgcg aataccgcgc cgacgcgggc
    10921 gcggcaaaac tggtcggcgc gccgaaaatg atttccgccc tgcaaaggct taaaggcaac
    10981 ccggtcgatt tgcccgaaga aatgaacgca atgggcatcg ccggagatac gcgcgactcc
    11041 ctgctcagca cccacccttc gctggacaac cgaatcgccc gcctcaaatc gctttaaacc
    11101 gatttgaaac ggcaaaaacc gtacgcgcaa gcagtacggt tttttgtata tgctgtctga
    11161 aaacatcagg tttccatacc gacaccaacc gtatccattt ccgcaccgga tacgccgcat
    11221 tgatataccc tgataaaccg tatccggaca gaaaatatag tggattaaca aaaaccagta
    11281 cggcgttgcc tcgccttagc tcaaagaaaa cgattctcta aggtgctgaa gcaccaagtg
    11341 aatcggttcc gtactattta tactgtctgc ggcttcgtcg ccttgtcctg atttttgtta
    11401 atcccctata tcagataaaa cagcggtaaa attgccgtct gaaaccaact ctgcgccata
    11461 cgggacacgc tctgcacgtc tatttgcctc cgatatatcc tccctactgt aggaacgtct
    11521 gccgatttgc acgaaatcgg cacctctagc acccttcagg atggcggacg ttatccgttc
    11581 ttgggattct gcaagacggt cgacggcatt atacagacgc tcggtctgat acccttccga
    11641 agcaacctgc ttcaggtatt ccaaataacc gtaacccaac gcccctccga caagcagggt
    11701 cgtcaacgct accagcgttg ccgaacggat tttagggggc atatcttgaa gcatatctct
    11761 accgaaccga accaaagtct ctttaaagtc ggactctaca cgcgtagaac cctcggaaat
    11821 cttgaagttc aactcatact gcttccgttt gtccgctgtc aaccgcttga ggttgtcatc
    11881 cccgtattgg acggttgaca caaccctgta cagactgtcc tgtatttcga ccagcgtctg
    11941 tgcaaagttg gcggtcataa ctggattccc aacccttgcc gccgattctg atactcaaaa
    12001 cggtatccag gcgttccagc agggcttcgg gagacagcag tgcgtattct tcaatatttt
    12061 ccataggttg attatagcag aaccttatac ctgttacaga caaggttgtc gggatttgaa
    12121 cgtccgtcga gcttggttcg tatagagccg tagggggtgt ttagggcttt ggcggcagct
    12181 tgtacgctgg ggaacgtgag tgtttcgcct gtggcggtgt cgaggatgga gacaggtttt
    12241 tggttttggg gaggcgtatt ttccttcatt ttaagtttcc cgcactccgg acacccatac
    12301 tttgacttta tagctgtgtc gtaatacaaa agttggacaa ccccgtgcgt aggacatcta
    12361 acactggaag gtttataaat gccactgaac tccaacaatt ctaaatgtgg aaatttctct
    12421 tgaaagcgtg atttggcggt atcgaaagtc attcgcttac ccataatttg tctccatagg
    12481 ttatgtgcaa atggattaca caaccaaaat atagaaattt tcaaattttt tgagacctac
    12541 ctgaaatcct gcgcaagcac aatgtaaaga aaaatggtat acgtctttac taaatcttta
    12601 cataaattaa ctctaatcgg gatttgaacg tccgtcgagc ttggttcgta ggatttaggg
    12661 ggttgtgaac cttacctatc gtacccaagc actttgtacc tgtttgaaat aaggttgtcg
    12721 ggcgacgttc gacccttgag cctgtgattg atttgttgga aatgcacacc taaagcagca
    12781 cctgcggcag taacgcttgg gaacgtgagt gtttcgttgg tcgttgtgtc gaggatgagg
    12841 aggggcttcc ctacatttgg aggtgtttgg gtttttgaca tcttagcaca ctcaggacac
    12901 ccgtactttg actttataag ggcattaaat gtcgaataac gaacgttccc gtgcatagga
    12961 caattaacgg ttactgggta attcacaccg tcaaagccgg ttagagagat attagggaat
    13021 atatcagtaa gttcagaagc tgcttggttg aaagatttgg ccatttgaga ctccaaaatt
    13081 gattgtcaaa tggatttaat agcaaattta taaaaatgtc aaatttttcg agaagcacct
    13141 gatagtggcg aggggtatac actgttaaaa agtgtatacg tcatttagtg cagatgtgaa
    13201 ccttatacct ccctgcaagt aaagtctctg tgtgaacccg accttttata cggtcagtga
    13261 tagctgctgg gtttataccc aatgaccttg cagcagatgc tcttgagggg aatgtaagtg
    13321 tttcgccagt tacagtatcc tccaatactg tatttttaga taatttatct attgtatctt
    13381 ctggaatttt gtgggaattg acaccataag atgcacattt tggacaccca cttttagagt
    13441 ccaacatact tttgaatgta gagcaagtaa ccctcccgtg tataggacag acgattaccg
    13501 tcgggtaacg aacgccattg aactccacaa gattcaaatg tggaaattta gaggttagct
    13561 tagaaactgc ttgagtaaat gtaagtgcca tagtggttgt gaacttactt taccaaccta
    13621 taacgatacc taatcaatcg gtcaaacgga gtgcgtccgc ttaaacgtac agctaaagtg
    13681 ctgttggagc aaccgataaa tttactggca gccagtgtac ttgcaaactc gtagatttcc
    13741 cctgtctctg tgtcctccaa cctaatggca acggcgtttg gagagggctt ttcgggattt
    13801 cgagtacatt caggacatcc tgttgaggat ttcatggcag cttgtagatt cccgtaaaca
    13861 accgacccat gcaaagggca ttggattgtt accggttcgt agtttttagt gaacttcaaa
    13921 accgtcttat caggaaattt actggaaaac cttaactgaa catcttgtag cgagagtgat
    13981 tttggcatta tagacctttt taaaatgaaa gcattataca accaaaatat agaaattttc
    14041 aaattttctc tgaacgcact ggtatccgat ggagctaaat gtaaagaaaa agggtatacg
    14101 tctttactaa atatttacac attttaactg tatagtgttt gacaaacaac aggcataggc
    14161 gcataatgca cccgtagtta gatagataga tagatagata gtaaggagat aaccaatgac
    14221 ttagcacctg ccccctctct ctctcgcgca ccccgcccct cgcttgcggc taatgggctt
    14281 tgcgcgacat atacactttc atctcctgca tggcttaacc gcctatgcaa tagtacacac
    14341 atcaacaaat caggctggca cgtcttggca ttggctgacg taccattgta gcccgaaatg
    14401 ttgataccct actatttatg accaacggcg gattagggct tcagacggca attttactgc
    14461 aaaaccttat gcgaacggat gatgcagcac aatcgtttct tctcggtcgg ggccggtgga
    14521 gacgatggcg accggcgcgc cgcagacttc ttcaatccgt ttcaaatatg ctttggcgtt
    14581 ttcgggcaat gcgccgtagt ccttcacgcc gaaagtggat tcacgccagc cgggcatggt
    14641 ttcgtaaatc ggcttgcagg cttctaccgc atcagagccg caaggcagga tgtcggtttt
    14701 gccgccgtcg ggcagttcgt agccgacgca gatattgatg gtttcaacgc cgtccattac
    14761 atcgagtttg gtaatgcaca taccggaaat gccgttgatt tggatggagc gtttcagggc
    14821 ggcggcatca aaccagccgc agcggcgcgc acgaccggtt acagaaccga attcgtgtcc
    14881 gcgctccgcc aaacctgcgc ctacttcgtc gaacaattcg gtcgggaacg ggcccgaacc
    14941 gacgcgcgtg gtataggctt tgacgatgcc caaaacataa tccagcattt gagggcctac
    15001 gcccgcgcct gccgaagccg cgccggcgag gcagttggac gaggtaacga agggataagt
    15061 gccgtagtcg atgtccaaca acgcaccttg cgcgccttca aacagcagtt tttcgccgtt
    15121 tttgtttttc tcgttcaaca cgcgggacac gtcggtaatc atcggcgcaa tgcgcggcgc
    15181 gactttttcg ataaccgcca tcacgtcttc cgctttaacc ggttcggcat tgtgcagatg
    15241 ttgcagttgg acgttgtaat aagcaaggac gacatccagt ttttcacgca gtttttcagg
    15301 atgcagcaaa tcggcggcgc gaatggcgcg gcgtgccact ttgtcttcgt aggcagggcc
    15361 gatgccgcgg ccggtcgtgc cgattttgcc tttgccgcgc gatgcttcgc gggcttggtc
    15421 gagcgcgatg tgataaggca ggatcagcgg gcaggtcggc gcgattttca gacggccttc
    15481 gacgtttttc acgcctgccg cgttcaactc gtcgatttcg cccaacaggg cttcggggga
    15541 gacgacaacg cccgaaccga tgaagcagtc caaactttca tgcaggatgc cgctcggaat
    15601 caggcgcaaa atggtttttt tgccgccgac aaccaaggta tggcccgcat tgtggccgcc
    15661 ttggaagcgc accacgccgc cggcttcttc cgccagccag tcaacgattt tacctttacc
    15721 ctcgtcgccc cactgtgcgc cgattactac aacattttta gccatagcca tataacctat
    15781 cgatattaaa aattattgcg gaaatcccca aaccggtgcg gctttgcgcc ccgccacgat
    15841 ttgcctttca tccgccatga acgggtattt agcgtttcac gacctgccaa acgccgtccg
    15901 tctttttcag acggcctgca agctcttccg aaacattgtg tccgataccg tagtcaatca
    15961 cgacacactg cccttgttca cgcaaggctt cgactgcttc gcgcgccgct tcggcatctt
    16021 ccgcatcgac caacacggcg ggctgccgtt cgatggtggg caaacgcccg ataaagctgc
    16081 gcaagtcgaa actgaatccc gttgccgggc gcgccctgcc gaaatatccg cccaatccgt
    16141 cataacgccc gccgcgcgcg accgcgtcgt ggaaatcggc ggcataggcg gcatacagca
    16201 agcccgtgtg gtaattgtcg acacgcagct cggacaagtc gatatggatt tcacaatcgg
    16261 ggaatgcgtc gcacaccgcc tgcaattcgc ccaacgcgcc gccgaccgcc gacaaatccg
    16321 gcaaccgtcc gcgcgcgtcg gacaacactt cacgcccgcc gtacaggcgc ggcagcagcg
    16381 agaatgcttt tgcccacata ccgtccagct tccaagcctt gacctgcgct tcgaccgtct
    16441 cggtatcttt atcctgcatc aaggcaagca gcgttgcaga ctgccccgca tccaaatgcg
    16501 ccgcatcgga caaggcgcga aatatgccga tatgccccag cgaaagcagc actttgccca
    16561 tatcggcaat tttcatgctt ttcagcatca ggtctatcag ctcgatgtcg ccacggatgt
    16621 cggcaaaacc gtacatttcc gcccctgcct gcaagggttc gcgcatattc agcagaccgt
    16681 cggactgcgc gtgcaacacc ggaccggcat aacacaaccg gttaatccct tggttggcgg
    16741 ataaaagatg ggcatcgata cgcgccacct gcggcgtgat gtcggcgcgt atgcccaact
    16801 gcctgccgct gagcctgtcc gttaccaaaa tggttttcag ggaaagcccc gcatcgatat
    16861 gcgtcagcag ggaatgtgcg tactccatca gcggaggctg taccagttca taaccgtgta
    16921 cgcggaacag tgccaacaac tgctccctcg cgctttcaag ctgccgcgcg ttcgtgggca
    16981 gtacgtcggc gatatgttcc ggaagctgcc atgtctgcat gagaatctgc cttctatttt
    17041 atcatgtaaa tacaaaaggc tgcccgatcc gcaatcagac ggcatctttg ccgcaacgca
    17101 tcacgccgct gtcaaaacgg cgatgcttcc ttccgattca gaatccgaac agcccctgtc
    17161 cgacggctca atgccgtcaa gtcgttaaaa ccaaacttta ccataaaata cacacaatct
    17221 gaatatactt ttataccctg tatccgccgt ctgacggcac ggcatttttt tactatataa
    17281 tgtgcgccat tatttctcat cacttcctgc tgccgttttc tgcttcagac ggcatttttg
    17341 ttgattgaac acttatgctg ctcgacctca accgcttttc cttttccgtc ttcctgaaag
    17401 aagtccgcct gctgaccgct cttgccctgc ccatgctgtt ggcgcaggtc gcgcaggtgg
    17461 gcatcggttt tgtcgatacc gtgatggcgg gcggtgcggg caaggaagac ttggcggcgg
    17521 tggctttggg cagcagcgcg tttgccacgg tttatattac ctttatgggc attatggcgg
    17581 cgctgaaccc gatgattgcc cagctttacg gcgcgggtaa aaccgacgaa gtgggcgaaa
    17641 cgggacggca ggggatttgg ttcgggctgt ttttgggcgt gttcggcatg gtcttgatgt
    17701 gggcggcgat tacgccgttc cgcaactggc tgaccttgag cgattatgtg gaaggcacaa
    17761 tggcgcagta tatgctgttc accagcttgg cgatgccggc ggcaatggta caccgcgcac
    17821 tgcacgccta cgcctccagc ctgaaccgcc cgcgcctgat tatgttggtc agctttgcgg
    17881 cgtttgtgtt gaacgtgccg ctgaactata ttttcgttta cggcaaattc ggtatgcccg
    17941 ctttgggcgg cgcaggctgc ggactggcga cgatggcggt gttttggttc agcgcgctgg
    18001 cattgtggat ttatatcgcc aaggaaaatt tcttccgccc attcggactg acggcgaaat
    18061 tcggcaaacc ggattgggcg gtgttcaaac agatttggaa aatcggcgca cccatcgggc
    18121 tgtcttattt tttggaagcc agcgcgtttt cgtttatcgt gtttttgatt gcgcctttcg
    18181 gcgaggatta tgtggcggcg cagcaggtcg gcatcagttt gtcggggatt ctctatatga
    18241 ttccgcaaag cgtcggctcg gcggggacgg tgcgcatcgg cttttcgctt gggcggcgcg
    18301 aattttcgcg ggcgcgttat atttcgggcg tgtcactggt gttaggatgg atgctcgccg
    18361 tgattaccgt gctttccttg gtattattcc gttcgccgct ggtaagtatg tacaacaatg
    18421 atccggcggt tttaagcatc gccgccaccg tcttactgtt cgccggcttg ttccaaccgg
    18481 cagacttcac ccaatgtatc gcctcctacg ccttgcgcgg ctacaaagtt acaaaggtgc
    18541 cgatgttcat ccacgccgcc gccttttggg gctgcggtct gctgccgggc tacctgctcg
    18601 cctaccgttt cgatatgggc atttacggct tctggacggc attgattgcc tcgctcacca
    18661 tcgccgccat cgccttggtg tggtgcttgg aattgtgcag tagggagatg gtcagatcgc
    18721 ataaggccgt ctgaaaactc cgccgattaa aaatatagtg gattaacaaa aaccagtacg
    18781 gcgttacctc gccttgccgt actatttgta ctgtctgcgg cttcgttgcc ttgtcctgat
    18841 ttttgttaat ccactataga aacgatgggc tgaagcccgc cactggcaat actcatttta
    18901 aagttcaaac ccatgcaacc catccgatac cgaaccgacc ttacccccta caacactttc
    18961 ggcctgcgcg cccaagcccg agcctttatt gcgcttgaac acgccgacgg gttgcgcgac
    19021 atcgtccggc tacccgagtt caaccgagat actgttttat ggctgggcgg cggcagcaat
    19081 atccttttga tggaggacta cgccggtctg gtcgtacata tggaaaacaa aggcatacgc
    19141 gaaattgctc gttcagacgg catggttctg attgaagcgc aggcgggcga aatctggcac
    19201 gattttgtcc tgcacgccgt cgcgctgggt ttgaacggtt tggaaaacct gagcctgatt
    19261 ccgggtacgg tcggcgcgtc gcccgtgcag aacatcggcg catacggcgt agaggcgaaa
    19321 gatgtgattc acagcgtgcg ctgcttcgat ttggatacgg aaacctttgt aaccctttcc
    19381 aatgccgact gccgcttcgc ctaccgcgaa agcctgttca agcaggaagg taaagggcgt
    19441 tatgtgattg tttcggtcgt atttgcatta aaaacgcatt ttgtgccgaa cttgggttac
    19501 ggcgatttgg cggccgccgt tgccgaactg agcgcgggca gggtgccgac ggcgaaagat
    19561 gtttccgatg cagtgtgtgc aatccgcaac agtaaacttc ctaatcctaa cgtgcttggt
    19621 aatgtcggca gtttctttaa aaatcccgtc atcggcgcgg aaaaagctgc cgccctgttg
    19681 gagcagcatc ccgatatgcc gcattatccg cagccggacg gttcggtcaa actcgccgcc
    19741 ggctggctga tcgaccaatg tcgtctgaaa ggcttccaaa tcggcggcgc ggcggtacac
    19801 gacaaacagg cattggtttt ggtaaacaaa aacaacgcct cggcaaacga tgtccggcag
    19861 ttggcgcaac acatcaaatt tacagtattt gctcggtttc aggtagaatt gcacgccgaa
    19921 cccaattggc tgcctgcttc gttcagcctg taaatccaag gagtatgccc gtgacccgcc
    19981 ccgccaaaat caatacttac acacgcatca tcgacgccag ccttgcgctt ttcaacgagg
    20041 aaggcgagcg caacatcagt accaaccata tcgcggcgca tttgggcatc agtccgggca
    20101 atctctatta ccacttccgc aacaaagacg aaatcatcgt ccaactgttc aaacgttaca
    20161 gcgaagccct gcttgcctac ctcaacgaag ccgtgttgcc gtctgatgtg gaagactcca
    20221 tcaactatat ggcgggcatt tacgacgtga tgtgggaata ccgcttccta ttcagcgacg
    20281 taaacaccct gcttgcacgc agtgccgaat tgttgggcga acacaacacc ttcacccaag
    20341 ccaaagtctc cccgctcttg gtcaacctgc tgacccagct caacggtctg aacatcatcc
    20401 aagccgacca aaccgctatg aacgatctcg ccgtcaatat gtggatggtt acgaaatact
    20461 ggttcgactt cgacagctcc ctgcgcggcc gcaccaagct gaccgaagac tccaaagcac
    20521 gcggcatccg ccgcacctta agcctccttc gtccttatct tttgcccgaa caccgcaaga
    20581 aatacgaccg gaaaatcggc aacggcaacc cgtaaaccca cagcgtccga atcagccttc
    20641 agacggcact tacccgacgg tatcagcgaa tgcgcgcagt ccccccgccc catatctcca
    20701 tcacaggcct aggttacctc ggcctgccgc tggcacaaaa gttttaccaa cacggcagcc
    20761 gcgtcgccgc cataaaacgc agcctgactt cggacgacat caacctgccc atacatctcg
    20821 acaccttcga cctcggcagc accgatgcct ttcagacggc attgtggcgg caccacgccg
    20881 acaaacccgt ctggttcttc ctgctaccgc cctcctcgct gacgcattac gccgacaccg
    20941 tcaaacaatg ggcagaactt gcccgggcgt gcaacgtgca acacctgatt ttcacaagca
    21001 gcaccagcgt ttacggcgat acagcgcgcg aatgcgacga aaccgccaca cccgatccgc
    21061 aaaccgagtc cgcccgccaa atcctcgccg ccgaacaaca cctgctcgac agcggcatct
    21121 ccaacatcga catcctgcgg ctgggcgggc tttattgcgc cgaacgccat cccgtcagcc
    21181 gccttgttca aaagcaaaac atcccgggcg gcaaccgccc catcaacatc gtccaccgta
    21241 atatcgccgt cgaaagcctg tttcagacgg catttaaccc cggcggcagg cggctgaaaa
    21301 acattatcga accgcgccac ccgacacgac gcgaattcta cacggaagaa gccgccaaac
    21361 tcggtttccc ggctcctgat ttcgcacccg acgacagcat gggcaaaatc atccgtaccg
    21421 tttgcgataa cagctgaagc ctgtaaaata agcgtcaaca gcaacaaaca ggcattctcc
    21481 gccccgatca gaaaatatgt ccgccctcct ccccatcatc aaccgcctga ttctgcaaag
    21541 cccggacagc cgctcggaac ttgccgcctt tgcaggcaaa acactgaccc tgaacattgc
    21601 cgggctgaaa ctggcgggac gcatcacgga agacggtttg ctctcggcgg gaaacggctt
    21661 tgcagacacc gaaattacct tccgcaacag cgcggtacag aaaatcctcc aaggcggcga
    21721 acccggggcg ggcgacatcg ggctcgaagg cgacctcatc ctcggcatcg cggtactgtc
    21781 cctgctcggc agcctgcgtt cccgcgcatc ggacgaattg gcacggattt tcggcacgca
    21841 ggcagacatc ggcagccgtg ccgccgacat cggacacggc atcaaacaaa tcggcaggaa
    21901 catcgccgaa caaatcggcg gattttcccg cgaatccgag tccgcaaaca tcggcaacga
    21961 agcccttgcc gactgcctcg acgaaataag cagactgcgc gacggcgtgg aacgcctcaa
    22021 cgaacgcctc gaccggctcg aacgcgacat ttggatagac taaccttcag acggcatccg
    22081 acatgaacag cccttttcac aacatcggca tcgtaacccg ccccaacacg cccgacatcc
    22141 aagacaccgc acacacgctg attacctttt tgaagcagca cggctttacc gtctatctcg
    22201 acgaagtcgg cataaaggaa ggctgcatct atacccaaga caccgtcggc tgccatatcg
    22261 tcaacaagac cgaactgggg caatactgcg acctggtcgc cgttttaggc ggagacggca
    22321 cctttctctc cgtcgcccgc gaaatcgccc tgcgcgccgt tccgattatc ggcatcaacc
    22381 aagggcattt gggcttcctg acccaaattc cccgcgaata tatgacggac aagctattgc
    22441 ccgttttaga agggaaatac cttgccgaag agcgcatcct gattgaggcc gcactcatcc
    22501 gcgaaggcaa aaccgccgaa cgcgccatcg ccctcaacga tgccgtcctc tcccgtggcg
    22561 gtgccggaca gatgattgag tttgaagtct tcgtcaatcg ggaattcgtc tatacccagc
    22621 gttcggacgg gctgattgtc tccaccccca ccggatcgac cgcctattcg cttgccgccg
    22681 gcggccccat catgcaggca ggattgcacg ccttcacgct cgtccccatc tgcccgcaat
    22741 ccatgaccaa ccgccccatc gccattccag acacgtccga aatcgaaatc ctcgttaccc
    22801 aaggcggcga cgcgcgcgtc catttcgacg gtcaaaccca tatcgacgtg caaaacctcg
    22861 accgcatcac catccgccgc taccgaaacc ccttacgcat cctacatccg accgactacc
    22921 aatatttcaa aaccctgcgc caaaaactgc actggggcga acaattggtc tgaaccgacc
    22981 cttaccggaa aacacctatg aatccaaaaa ctccccccga ccatacagaa gatgccgtgc
    23041 gcctgtccaa acgcatggcg caactggggc tttgttcgcg ccgcgaagcc gacggctata
    23101 tcgaacaggg ttgggtaacg gtcaacggca aaaccgccgt actcggtcag aaagtttcgc
    23161 cggcagaccg tatcgaacta aacaagaaag cccacgaaca gcaggcggca cgcattacca
    23221 tcctgctgaa caaacccgtc ggctatgtca gcgcacaagc ggaaaaaggc tataaatccg
    23281 ccgccgaact gattacctct gaaaaccgct gggaaagtga caccagccgc atccgtttcg
    23341 atccgaaaca caaaatcggt cttgccccgc cggcaggctc gatatcgatt cagtcggatt
    23401 actggtgttg acgcaggacg gccgtatcgc caagcagctt atcggcgaaa acagcggcag
    23461 tgaaaaagaa tatttggtgc gcgtgcgcgg aaaattggac gaaaaaggac ttgccttact
    23521 gaatcacgga ttgagtttgg acggtgagaa actgcgtccc gcccaagtag aatggcaaaa
    23581 cgaagaccaa ctgcgcttcg tgttgaaaca gggcaaaaag cggcaaatcc gccgtatgtg
    23641 cgaactggtc ggactgcgcg tcgtcgggct gaaacgcatc cgcatgggta aggtcaagct
    23701 cggcaggctg ccgcccggca aatggcgtta tctcgccccc ggtgaatcgt tttaaataag
    23761 cattaaaaaa tgccgtctga aaatccttgc gttttcagac ggcattgcct tatgcccaaa
    23821 taacggtttc ttccaagggc ctgcgcgcct tcgtggcgat ttcctgaacg cggtaaccga
    23881 atgtcgcggc gacggacacg ccccattctg ccgcatcgaa caaaccgaac tgcccggaca
    23941 atacgcgttc catatcggca tagttgaaac cttccaccgg gcaggaatcg atacctgcca
    24001 tcgccgcacc cgtcatcatg ttgcccaacg cgatataggt ctggcggcaa caccagtcaa
    24061 acaaggcgcg cgaatcgtcc aaaatcttga tgtcgtcggc ttgaaacgcc tgatacctcg
    24121 ccaaagattt tgccatggca tccggttcgg taacgccgcg ccgtttgagg ctttccaaca
    24181 taaacgggct gtcgaagcgg gcatttttct ttgccaaaaa caccaccaaa tgactggcgg
    24241 tatccaaagc atccgccata ccccaagaaa acggcttgat tgcctgtcgg atttcggggt
    24301 tttgaaccac aacaaactgc caaggctccg aaccgaccga actgggcgac aaacgcccga
    24361 gttctaaaat aaactgaaaa tcctcggcac tgattttgcg tgccgcatcg taatgccggc
    24421 atgatttacg gtttttaaat gcggatagaa cctgctctct gtctaatacc gtcatagtgc
    24481 atccttttat tactggtatt gcaaattgat ttcaaaccga tacggcactg ccgcaccata
    24541 caatccgtcc tcgccatcaa gcttcatccg gactttaccc atctctctac ggctgggaaa
    24601 acaaagcggc ggcagactcg ggaataacgc cccaatgcct ttcagacggc atttgggcat
    24661 cattgcaaac gcgcctacgg gtaggcgata taggcataag ccgaatggtt gtggatagac
    24721 tcgaaattct cactctcgac gacgaaactc ttgatgcgtt tgtcagcgat cagcgaagta
    24781 gcgacatcac gcaccatatc ttccacgaat ttcgggtttt cgtaggcttt ttcggtaaca
    24841 tatttttcat cggggcgttt gagcaaaccg tagagttggc agcttgcctg cgcctccaca
    24901 taatcaatga cttcctcgat accgacttct gcatcggcag tcaggctgac ggtaacatgc
    24961 gaacgctggt tgtgcgcgcc atattgggaa atttctttgg aacacgggca aagcgaggtt
    25021 acgggaatca tgaccttcat actgtagccg tatgccccgt ctttcatttc gcccgtgaga
    25081 cagacatcat aatccagtaa ggaccgaata ccggaaaccg gcgcggtttt cttgcggaaa
    25141 aacggaaaag aaacgctgat tttgccggcg cgggaatcta aaagcgcgac catttcggca
    25201 gtcagcctgt gcaattgtgc aaaatccaag gcttcagaat gttgctccat caatgcgaca
    25261 aaacgcgaca tatgcgtccc cttctgctca gcaggcaggt aaaccgtcat ggtcagacgg
    25321 gcaacggtgg actggatgcc ttctgcagtt tgcagggtaa tcggaaagcg caggtctttg
    25381 ataccgacct gattgatcgg cagattgcgc aaatctcggc tggattgcac gtctgcaata
    25441 gtgttcatga gttgtttttc cttaatattc atgtaattgt tgagatgtgt gcatggtatg
    25501 gcgtttccgc cggggaatat accgtcaatc tgcaaatgcg agattatatc actcgctttt
    25561 agcagctgca ttgattgttt ctatttttca gatagtgata aaatcttcga ttattcacat
    25621 ctacataggc agagaccaaa tgaaattcgc cacgaaagcc attcattcca gctacgattg
    25681 cgacgaacac aaccgcgcgc tgatgccgcc gatttatcaa aacagtatgt ttacgttgca
    25741 cgagattggc gaaaatgtgc cttaccgtta ttcgcgcctg agcaacccga cccgtcagat
    25801 tttggaagac accgttgccg atttggaaca cggtgcggca ggctttgcgt tttccagcgg
    25861 tatggcgggg attgatgccg tatggcgtac cttcctgcaa ccgggcgata ccatcgtcgc
    25921 ggtcgccgat atttacggcg gcgcgtatga cttattggtc gatgtttatc aaaaatgggg
    25981 ggtaaatgtt gtttttgccg atttaggcaa tcccgacaat ttggacgaat tgctcaaagc
    26041 gcacaaggtc aaactggttt ggctggaaac gccgtccaat ccgcttttac gcttggtaga
    26101 catcaaagcc cttgccgcaa aagccaaagc gaccggcgcg ctggtcggca tcgacaacac
    26161 ctttgccacg ccgtatctgc aacagccgtt ggatatgggt tgcgattttg tgttccattc
    26221 cgctaccaaa tatttgtgcg gccattccga cgtattgatg ggcatcgtcg ttgccaaaac
    26281 caaagagctg gctcagcctt tgcacgatat gatggtgcat accggtgcga ttgcaggccc
    26341 aatggactgc tggctggtgt tgcgcggcat caaaacgctt gccctgcgta tggaggcaca
    26401 ctgcaaaaac gcactcgaaa tcgcgcgccg tctggaagac catcctgcca ttgaaaaagt
    26461 gttccatccc ggcctgccgt cgcacgaaca ttatgaactc gcccaagcgc aaatgcctaa
    26521 aggcatcggc ggcgtggtga cggtttatct caaaaacgac acgcgcgaag cggcaaacag
    26581 cgtgattaaa aacatgaaac tggtcaaaat ggcttccagc ctcggcggcg tggaaagttt
    26641 ggtcaaccat tgctattccc agtcccacag cggcgtgccg cataatgtga aaatggaaat
    26701 gggcatcaaa gtcggcctgc tgcgtttctc catcggcatc gaagacgcgg acgatatttg
    26761 gaacgatatt tccgccgcac tcgatacgac tttgtaaact gtaaaaatgc cgtctgaaac
    26821 catggtttca gacggcattt caattaaccc ggccgaaaat caacgcttca acatctttgc
    26881 cgcctcaata gcgtaatagg tcaaaatccc gtccgcaccc gcacgtttga atgccagcag
    26941 gctttccaaa accactttgc cgccgtccag ccagccgttg gcaatcgctg cctgcaacat
    27001 cgcgtattct cccgaaacct gataggcata agtcggtacg ccgaactcgt ccttcacgcg
    27061 gcggacaacg tccaaatacg gtaaaccggg cttcaccatc accatatccg caccttcccg
    27121 aatatcgagc gccacttcat tcagcgcctc atcggtattt gccggatcca tctggtaggt
    27181 tttcttgtcc gccttgccca aattgcccga actgcccacc gcatcgcgga acggcccgta
    27241 aaacgccgaa gcatatttgg cggaatacgc cataatccgc gtgtggatat gcccggcatc
    27301 ctccaacgcc tcgcgaatcg caccgatacg cccgtccatc atatcggaag gggcaaccac
    27361 ctgtgcgccc gcttcagcgt ggcacaaagc ctgcttgacc aaaacctcta cggtttcatc
    27421 gttcatcaca taaccgtttt cgtccgtcag cccgtcctga ccgtgaaccg tataaggatc
    27481 gagcgcgaca tccgtcataa tgcccagttc gggaaacctc tcgcgcaggg cgcggacggc
    27541 tgccggcacg agtccttcgg gattgtacgc ttcctctgca cgctcggttt tgtttgccgt
    27601 aaccacggga aagagtgcca acatcggaat accgagcttt accgcctctt ccgccgtaaa
    27661 cagcagcctg tccaaacttt gacgcttcac acccggcata gaaggcacat cctcctcgcg
    27721 cgccgacccc tccaatacga acaccggata aatcaaatca tcggcggtca gcgtgtgttc
    27781 gcgcatcagg cggcgtgaaa aatcgtccct gcgcatacgg cgcatacgcg aagccggaac
    27841 attgcggtaa ggaaactgca taagccctcc aatcatcctg tcaacaattc aaaccatacg
    27901 gaagccgccg caacttgcag acagcatcgg gcggcaatca aaatccgttt tcaccggaaa
    27961 gggtttcggc ccgccgaaat gccgcgccga aggacggcgt cccgcccatt aaagaacaat
    28021 agcaaaacaa cagcttcagg ctgtcagcct tcgatattct tacgccacaa taccaaaagt
    28081 ttcccgatat gctgaacagg ttgcgcgtca accgcctcac ataaggcagt gcagatttcg
    28141 atacgttcgg cacggtcgtc gccgaatacg cgcactttaa tcagctcatg cgccgtcaat
    28201 gccgcatcgg tttccttgat gaccgcgtcc gtcagaccct gctgaccgac catcacaaca
    28261 ggatggagat ggtgcgcgcg cgctttcagt tccaaaattt ctttggtgtt caatttggta
    28321 tccgtcattt tcctactgct tgaataaaaa gaataatgcg gcattgtacg cgatttggca
    28381 cgacatcggc aaaattaacg tacaatacgc ggtttccatt ccgacccgcg aaccactatg
    28441 gctgtacgtt ccaaatcctc aaaagcgtgg ctgcacgaac acgtcaacga ccactacgtc
    28501 catatggcgc aaaaagacgg ctaccgcgcc cgtgccgcat acaaactttt ggaaatcaac
    28561 gacaaagaca aattaatcaa acccggcacg gtacttgccg acttgggcag cgcgccggga
    28621 agctggtcgc aggttgccgc caagctgacg ggttcttccg gagcagtttt cgccttggac
    28681 atcctgccta tggaagccat agggggcgtc tccttcattc agggcgactt ccgcgagaac
    28741 gacgtactgg cacaattcga aaccttgttg gacaaccgcc cgctcgacct tgtaatttgc
    28801 gatatggcgc ccaatatgtc gggaaacgcc gtaagcgatc aggcacgcag cttttatctg
    28861 tgcgaactgg ctttagactt cgcctcgcaa cacctgaaaa ccggcggcag ctttttggtc
    28921 aaagtctttc agggtgcagg ctatcaggaa tacatggcag ccatgcgcga aattttcggc
    28981 acggtgcaga cgcgcaaacc cgaagcctcg cgcaatcgct ccagtgagat ttatttattg
    29041 ggcaaaaata aacgctgaca atacagacgg cgtgctttac aatcatttcc gttttacacc
    29101 tcaattatgg agccttgcta agtggggaac acctttaaat caatccttgt ctgggtcgcc
    29161 ttgggtatcg gcctgatggc tgcgttcaac gctttagacg gtaaaaaaga agacaacggg
    29221 caaatcgaat attctcagtt catccaacag gtcaacaacg gcgaagtatc cggcgtcaac
    29281 atcgaaggat ccgtcgtcag cggctacctg attaagggcg agcgcaccga caaaagcacc
    29341 ttcttcacca acgcgccttt ggacgacaac ctgattaaaa cactgctcga caaaaacgtc
    29401 cgtgtaaaag taacgccgga agaaaaaccg agcgcgctgg ctgccctgtt ttacagcctg
    29461 ctgcccgtcc tgctgctgat tggcgcgtgg ttctacttta tgcgtatgca gacgggcggc
    29521 ggcggcaaag gcggcgcatt ctcattcggc aaaagccgcg cccgcctact ggacaaagat
    29581 gccaacaaag tgacctttgc cgatgtcgcc ggctgcgacg aagccaaaga agaagtgcag
    29641 gaaatcgtcg attacctcaa agcgccgaac cgctatcaaa gcctcggcgg tcgcgtgccg
    29701 cgcggcatcc tgctggcggg cagcccgggt acgggtaaga cgcttttggc aaaagccatt
    29761 gcaggcgaag ccggcgtgcc gttcttcagc atttccggtt ccgactttgt cgaaatgttc
    29821 gtcggtgtcg gtgcgagccg cgtccgcgat atgttcgagc aggcgaagaa aaacgctccc
    29881 tgcatcatct ttattgatga aatcgacgca gtcggccgcc aacgcggcgc aggtttgggc
    29941 ggcggcaatg atgagcgcga gcaaacatta aaccaattgt tggttgaaat ggacggtttt
    30001 gagagcaatc agactgtaat tgtgattgcg gcaaccaacc gccccgacgt actcgatcct
    30061 gcgctgcaac gccccggccg tttcgaccgc caagtggttg tccccctgcc ggacatccgg
    30121 gggcgcgaac agattttgaa cgtccattct aaaaaagtgc ctttggacaa atctgtggat
    30181 ttattgtccc tcgcgcgcgg cacgccgggt ttttccggcg cggatttggc gaacttggtc
    30241 aacgaagccg ccctgtttgc cggccgccgc aataaagtca aagtcgatca gagcgatttt
    30301 gaagacgcca aagacaaaat ctatatgggt ccggaacgcc gcagtatggt gatgcacgaa
    30361 gacgaaaaac gtgcgacggc gtatcacgaa tccggacacg cgattgttgc cgaaagcctg
    30421 ccctttaccg accccgtcca caaagtaacc attatgccgc gcggacgtgc gctgggtctg
    30481 acttggcagc ttccggagcg cgaccgcatc agtatgtata aagatcagat gttgagccag
    30541 ctctccatcc tgttcggcgg acggattgcc gaagacatct tcgtcggacg catctccacc
    30601 ggcgcatcaa acgactttga acgcgcaacc caaatggcgc gcgaaatggt aacgcgctac
    30661 ggcatgagcg acaaaatggg cgtgatggtt tatgcggaaa acgaaggcga agtcttctta
    30721 ggacgcagcg taacccgttc gcaaaacatt tccgagaaaa cccagcagga catcgatgcg
    30781 gaaatccgcc ggattttgga cgagcagtat caggttgcct acaaaatcct cgatgaaaac
    30841 cgcgacaaga tggaaaccat gtgcaaagcc ctgatggaat gggaaaccat cgaccgcgat
    30901 caggtactgg aaatcatggc gggcaaacaa cccagtccgc ccaaggatta cagccacaac
    30961 ctgcgcgaga atgcggacgc ggcggaagat aacgcgccgc acgctccgac tcgggaagaa
    31021 accgaagcac ctgccccggc agacaccgct tcgacagagt ccgagcagca gcctgaaaac
    31081 aaggcttaac ttcccgaaca aacggcagcc cgcaagctgc cgttttccca tcctgttttc
    31141 agacggcatt ttccgctcaa tgccgtctga aacgccaaag ccgtatcggt ttttgcggat
    31201 ctgcgatatg gcggtttaaa ttgaaatcag acgaggcaag gctgtactgg tttaaaatta
    31261 aaccgctata ataccgcctt tcgaatacac gcccgcattg gtgatgcctg tgaaaaaagt
    31321 tgaaaaaaac atcttggtgc tgcacggcgc ggacaaaatg ttcgagctgg tcgataaggt
    31381 tgaagactat ccgcactttc tgccgtggta cagcaagacc gaggtcatcg ggcgtagcgg
    31441 caacgaactg aaggcgcggc tgtttatgga ctatatgcac gttcgccaat cattcgccac
    31501 gcacaaccgc aacattccgg gcagggaaat ccgtatggaa ctgctcgagg gtccgttcaa
    31561 aaccttacgt ggaacgtgga aatttatcga tttgggcgac gatatgtgca aaatcgaatt
    31621 caatttggaa tacgattttt ccaatgccgt tttgtccgcc ttaatttccc ccgtcttcaa
    31681 ccacctttcc gccacgctgg tcgaagcgtt cgtcaaagag gcagaccgcc gttatgcttg
    31741 aaattgagat tgtgtacggg ctgcccgacc gacaggtttt gaaaaccatg cagcttgccg
    31801 agggaacaac cgtccgcgcc gccgcactgc aaagcggttt ggacggcata tttgaagatt
    31861 taaacctgca ttccgcgcct ttgggcattt tcggcaaagc cgtcaaagac gacacgcccc
    31921 tgcgcgacgg cgaccgcatc gaagtgtacc gcccgctgtt gatcgacccc aaagaagcgc
    31981 gccgcaaacg cgttcaaaat caagaagaat aaccatgccg tctgaagcct tcagacagca
    32041 ttcgacagaa acacggaaaa tatcatgtca aacaaaatca aaatgcttgt cggattgggc
    32101 aaccccggca aagaatacga acaaacccga cacaatgcgg gtttttggtt cctcgacgaa
    32161 ctggcgtgga aatggaaggc ttcatttaaa gaagaaaaaa aattcttcgg cgaagtcgcc
    32221 cgtgccgccc tgcccgacgg cgacgtttgg ctgctcaaac ctgccacgtt catgaaccgt
    32281 tccggacagg cagttgccgc gcttgcacag ttctacaaaa tcaaacccga agaaatcctc
    32341 gtcgtccacg acgaactcga cattccctgc ggacggatta aattcaaact cggcggcggc
    32401 aacggcggac acaacggctt gaaagacatt caggcaaaac tcggcacggc agactattac
    32461 cgcctgcgcc tcggtatcga ccacccgggc gaccgcaacc tcgtcgtcgg ctatgtcctg
    32521 aacaaaccca gtacggaaca ccgccgacag attgacgatg ccgtcgccaa atccctgcaa
    32581 gccatacccg acatccttgc cggcaaatgg gaagaagcaa cccgcttcct gcacagcaaa
    32641 tgacccgatg ccgtctgaag ccctttcaga cggcatgttc ccgatttcca tatccgaaca
    32701 gtcatgaccg aactcaagca gcttatccaa accgaatcca tccccgtcat cgaagaaacc
    32761 ctcgatttcc tgctgtacga atgcagcatc gacgacgcac catccgccga agaagtggca
    32821 caatggcgcg acatacttgc cgcacgcggc ggcaaattcc tgcgcctgtc caaaatctgc
    32881 caaacgtggc tggacgagga ggcggcatga agctgccgcg caaccgcttc agcctgcttt
    32941 ccgcattgtg gtttgccggc ggcatctatt cgctgctctt caaagctgcc gacaccgcgc
    33001 cgccgccgtt tccgcatttc gacaaagcag cacaccttgc cctgtttttc gcacaaatct
    33061 ggcttttgac caaagcattc aaaaccggaa aacttcccat cccctaccgc agcctgatgg
    33121 tctttgccct ctgtttcgcc ctcttcagcg aatgcgcgca ggcatggttt accgcaacga
    33181 gaaccggcag tttgggcgat gttcttgccg atatggcagg tacggttctc gcactctttg
    33241 ccgcccgcgc cgccgaccgc ccggactgaa tcggtttatt tcccccaaac aggatgcacc
    33301 tcttcccgat acatcctatt tttcccctta catatcaatc ccatctcata aacaaaaccg
    33361 acaaatcgtt tacaatatat ttacactaca tcagattaca aatatactcg aaccagttgt
    33421 agaatcggcg gttccacaaa ccgtttcgga ttgcacgaca caaaagaaaa accgatttta
    33481 ttgccttaaa ggagtattca tgaacctgca tgcaaaggac aaaacccagc atcccgaaaa
    33541 cgtcgagctg ctcagtgcgc agaagccgat taccgacttt aagggcctgc tgaccaccat
    33601 tatttccgcc gtcgtctgtt tcggcattta ccacatcctg ccttacagcc ccgatgccaa
    33661 taaaggtatc gcgctgctga ttttcgttgc cgcactttgg tttaccgaag ccgtccacat
    33721 taccgtaacc gcactgatgg tgccgattct cgccgtcgta ctcggtttcc ccgacatgga
    33781 catcaaaaag gcgatggctg atttttccaa cccgattatc tacatttttt tcggaggctt
    33841 cgcgcttgcc accgccctgc atatgcagcg gctggaccgt aaaatcgccg tcagcctgtt
    33901 gcgcctgtcg cgcggcaata tgaaagtggc ggttttgatg ttgttcctcg ttaccgcctt
    33961 tctgtccatg tggatcagca acaccgccac cgccgcgatg atgctgcctc tagcaatggg
    34021 tatgctgagc cacctcgacc aggaaaaaga acacaaaacc tacgtcttcc tcctgctcgg
    34081 catcgcctat tgcgccagca tcggcggctt gggcacgctc gtcggctcgc cgcccaacct
    34141 gattgccgcc aaagccctaa atctggactt cgtcggctgg atgaagctcg gcctgccgat
    34201 gatgctgttg attctgccct tgatgctgct ctccctgtac gtcatcctca aacctaattt
    34261 gaacgaacgc gtggaaatca aagccgaatc catcccttgg acgctgcacc gcgtgatcgc
    34321 gctgttgatt ttccttgcca cagccgccgc gtggatattc agctccaaaa tcaaaaccgc
    34381 cttcggcatt tccaatcccg acaccgttat cgccctgagt gccgccgtcg ccgtcgtcgt
    34441 cttcggcgtg gcgcaatgga aggaagtcgc ccgcaatacc gactggggcg tgttgatgct
    34501 cttcggcggc ggcatcagcc tgagcacgct gttgaaaaca tccggcgcgt ccgaagcctt
    34561 gggacagcag gttgccgcca ccttttccgg cgcgcccgca tttttggtga tactcatcgt
    34621 cgccgccttc attatttttc tgaccgagtt caccagcaac accgcctccg ccgcattgct
    34681 tgtaccgatt ttctccggca tcgctatgca gatggggctg cccgaacaag tcttggtatt
    34741 cgtcatcggc atcggcgcat cttgtgcctt catgctgccg gttgccacac cgcctaacgc
    34801 gattgtgttc ggcacgggct taatcaagca acgcgaaatg atgaatgtcg gcatactgct
    34861 gaacatcctc tgcgtagtat tggttgctct gtgggcttat gctgtactga tgtaaaccat
    34921 cgacctaaac aacaagaccg tctgaaagaa tatttttcag acgaccttga agtttgtcgt
    34981 tcagacacaa tttgtcgaat cattcaaaac cggattctaa cgaaaggaaa cccatgatta
    35041 tcctgcacac caacaaaggc gacatcaaaa tcgaactcga tttcgacaaa gcccccgtta
    35101 ccgccaaaaa cttcgagcaa tacgtcaaaa acggcttcta cgacggcgta atcttccacc
    35161 gcgtcatcaa gggcttcatg attcaaggcg gcggcatgga tgaaaacatg aacgaaaaag
    35221 aaacccgcga tccgattcaa aacgaagcgt ccaacggcct gcccaacgat aaatacacca
    35281 tcgccatggc gcgtacttcc gatccccatt ccgccagcgc gcaattcttc atcaacactg
    35341 ccgacaacgc tttcctgaac ttccgttcta aagagctgta cggcaaaacc gtcgtccaag
    35401 actggggcta tgccgtattc ggtaaagtcg ttgacggttt tgacgttgtc gatgccatcg
    35461 aaggcgtttc taccaaacgt catggttacc acgacgacgt accgagcgaa cctgtcgtca
    35521 tcattaaagc cgaagcggta taaaccgaca atccgaaagc agcctgcaca aaggctgctt
    35581 ttatttcaga cggcatgtta tttgatgtaa ccgtgctatg ccgtctgaaa accggacgca
    35641 agccttcaga cggcataccg ctatgttaaa atatgcccgt ttttcctaaa cggacacaaa
    35701 ggaaacctta tggcaagcat cgcccgcgac atcttcaaag cctacgacat ccggggtatt
    35761 gtcggcaaaa ccctgaccga cgaagccgcc taccttatcg gcaaagccat cgccgccaaa
    35821 gccgccgaaa aaggcattac ccgcatcgcg ctcggacgcg acggacgctt gagcggtccc
    35881 gaactgatgg aacacatccg gcgcggcttt accgacagcg gcatcaatgt cctcaatgtc
    35941 ggtatggttg ccactcctat gctctacttc gccgccgtca acgaatgcgg cggcagcggc
    36001 gtgatgatta ccggcagcca caatccgccc gattacaacg gctttaaaat gatgctcggc
    36061 ggcgacacgc ttgccggcga agccatccaa gaacttttgt ccatcattga aaaagacggt
    36121 tttgctgccg ccggcaaaca aggcagcgtc accgaaaaag acatctccgg cgaatacctc
    36181 aaacacatta ccggacacat caggctcaaa cgcccgatga acatcgccat tgacgcgggc
    36241 aacggcgtgg gcggcgcgtt tgccggcaaa ctctacaaag gcttgggcaa cgaagtaacc
    36301 gagcttttct gcgacgtgga cggcactttc cccaaccacc atcccgaccc atccaaaccg
    36361 aaaaacctgc aagatttgat tgccgcgctg aaaaacggtg atgccgaaat cggcttggcg
    36421 tttgacggcg atgccgaccg cttgggtgtg gtcaccaaag acggcaacat tatttatccc
    36481 gaccgccaac tgatgctttt cgcgcaagac gtgttgagcc gcaatcctaa agccaaagtg
    36541 attttcgacg tcaaatccac ccgtctgctt gcgccttgga ttaaagaaca cggcggcgaa
    36601 cctgtgatgg aaaaaaccgg ccacagcttt atcaaatccg ccatgaaaaa aaccggcgcg
    36661 ccggttgccg gcgaaatgag cggacacatc ttcttcaaag aacgctggtt cggcttcgac
    36721 gacggtctgt acgccggcgc acgcctcttg gaaatcctgt ctgcctccga taatccgtcc
    36781 gaagtgttaa acaacctgcc gcaaagcatt tccacgcccg aactcaacat cgccctgccc
    36841 gaaggcagca acggccatca ggttatcgac gaactcgccg ccaaagccga atttgaaggc
    36901 gcaaccgaaa tcatcaccat cgacggtctg cgcgttgaat ttcccgacgg cttcggtctg
    36961 atgcgtgctt ccaataccac gccgattctg gtgttgcgtt ttgaggcgga tacgcaagaa
    37021 gccatcgagc ggattcaaaa ccaattcaaa gccgtcatcg aaagcaatcc gaatctaatc
    37081 tggcctctgt aaacacagga aaaatgctta atcaaatctt ggtagattgg atttggctta
    37141 aaaatctccg cgtccgttcg tgtttggggt ggtcgaacaa ctctttcggg ctgccctgct
    37201 ctacgataac gccgccgtcc atcacgacaa cggtagtcgc aacttccagc gcgaacttga
    37261 tttcgtgggt aacgacgacc atcgtccaac cttcccgcgc caattccttc atggcgttca
    37321 acacgtcttg caccaactcg gggtcaagcg cggaagtcgg ttcgtcaaac agcatcagct
    37381 cgggctgaat cgccaatgct cgggcaatgc cgacgcgctg ctgctgaccg ccggaaagct
    37441 ggtagggata caaatccact ttgtcgccca agccgacttt ttccagcagt ttcagagcct
    37501 cttcgcgcgc ttgggcggca ggcttgccct gtacggcaac cggtccttcc atcacgtttt
    37561 ccaaggcggt tttgtgcgga aagaggttgt attgttgaaa caccatgcct gatttgcggc
    37621 gcagtgccaa aatatcgtgt ttgcttggtt ttttagaaaa atcgattttc agcggtcgct
    37681 cgttgtcgaa ctcgatttgt ccgtcttcgg gcatttccaa cgcgtttagg catcgcagaa
    37741 acgtcgtttt gcctgagccg gaaggcccga ggatgacgac cacctgccct ttgcacacat
    37801 ccaaattgat gccgcgcaaa atggtatttt cgccgaaggt cttatggata ttgcggattt
    37861 taatcatgac aactccttat ttggcgacat agcggtcgaa gcgtttttcc aagcgcgcct
    37921 gaatcaggaa cagcactttg caaaaacacc agtaaaccaa agcggcttcg atatagacgg
    37981 gcaaaaagtc ataagtgcgg tttgccgttt cctgcgcgac gcggaataat tccgttaccg
    38041 tcacgactgc cgcgagcgag gtgtttttaa acaaaccgat aaactcgttg ctcaaaggcg
    38101 gcacggcaac gcgaaatgcc tgcggcgcga cgatgcggcg gaacgtctgc atataggtca
    38161 tgccgatgga gaaacctgct tcccattggc ctttcggtac ggacaaaatt gccgcgcgta
    38221 tggtttcgga agcatatgcg ccgacattga gcgaaaagcc gatgatggcg gcaggaatcg
    38281 ggtcgatata gatgccgacg gaaggcagcc cgtaaaacac aatcacaagc tgaaccaaca
    38341 gcggcgtacc gcgaatgacg gaaatataaa attccaccaa tttcagcagg attttccgca
    38401 cgatgccgcc ggcgggcata atccgcacca aagccacggc taccgcaatc atcataccga
    38461 taacgaaaga agctgccgcc aaaggcagag agaccgcgaa gccggctttg accataggca
    38521 aaaacgcgct gacaatcata tcggcgcgtg tttccgtcat aaacggcagc gaagcaagga
    38581 aattattgaa cactgatgtc ttttccgaag aattgttcgc ccagtttttt cagcgtaccg
    38641 tcggctttca gctcgttgat tgccgtactg aatttcgcca cggcttcgtc attgcccttg
    38701 ttgacaatca ggccggaacc gactttttca tcggcaggtg cggaccaaac gattttcacg
    38761 cccgcattcg ggtttttctt cagatagtcc aaaaccgcca attcgtcgtt cagggttgca
    38821 tcggcacgtt tttgttcaat cagggtcagc gattgcgcca aaccgtccac tgccaccaaa
    38881 tctgcgcctg cagctttggc tttttcgccg tagttgctgg tcagggattg tgcggttttc
    38941 acgcctttga tgtcgtcgat agatttgatg ttgctgtcgt tacgggcaac caatacggca
    39001 ccactccagc tgtaaggatc ggatttgtcg aatgtcgctt ggcgttcggg gctggtcaga
    39061 ccgacttggt ttgccaccac gtcgaaacgc cccgccttca aacccgccat catcgaatcc
    39121 cattgcgttt ctttaaactc gactttcacg cccagttttt ccgccacggc gcgggttact
    39181 tccacatcgt aaccggtcag tttgccgtcc ttgtcgtggt aggtaaacgg tgcgtaagtg
    39241 ccttccgtgc cgacggtaac cgtgccttta ttgttgatgc gctcgattaa agaaccggaa
    39301 actgccgatt gtgcaggcgc ggaagatgct ccgctgccgc tttccgaacc gccgcaggcc
    39361 gccaaaacca atgcggcaat gccgccgagt acgaattttt tcaacatcat tctctcctgt
    39421 aaaaagtgtg caagtgcggc attctaagtg aaattgcggc aaacacaaag aatacttttt
    39481 ttatatggtt attccaaatc ggaatggaaa agatatgccg aagccgccgg aagcggaaat
    39541 aaagggggcg ggaaaggcga cgggcggcac gaaaccgaaa agcggcatca ggtatgcaaa
    39601 cggcggattc acgcacgccg ttccggcaaa aatccgcctg ccgattcggt gctataatcc
    39661 atccgaaaca gatgacacca aaaaggaaca tctcatgaac acgccccaat ccgccatcat
    39721 tcccgaccac gcccaagccg gcatctttat cgaagccgac ttcgccgcca accgcctcaa
    39781 cgatattaaa gccgcctgcc gcgcttcgct cgacgcgtta tccgccttga aaacccgctt
    39841 tccggacgat attttgggtc tgaccatcgc cttcggcagc aaagcctggg caacattcgg
    39901 acatacggac gaaggcagtg aaatcaaacc cttctccgaa atgggcaacg ggcttgcgcc
    39961 gtccacgcag cacgatatgt ccatccacat ccaatctttc cgccaaaaca ccgcctacgc
    40021 gcttgcccaa tccgttttgg gcgcgttcgg cgacagcata tgcgtcgcgt ccgaagaaca
    40081 cggtttgcgc ctgtatcagg atcgcgggct ggacggtttc gtcgacggca cggaaaaccc
    40141 gcagggcgat gaaaatgtcc gcgaagtcgc catcatcccc gaaggaaaac ccgatgcggg
    40201 cggcagctat gtcctgctgc aaaaatacct gcacgatttg aaaaaatggg atgccgtccc
    40261 cgtcgccgaa caggaggcct cggtcggacg cggcaaggaa accgacgacg aattcggccg
    40321 cgatgtccgc ctgcccgatt cgcacctcgg ccgcgtcaac ctgaaagaaa acggagtcgg
    40381 cctgaaaatc gtccgccgca gcctgccctt cggcaaaatc agcggcgaac acggtttgat
    40441 gtttaccgca tactgccgca cgctgcacaa tatcgaagcg caattattga gtatgttcgg
    40501 cgatacggac ggcaaaaccg acctgctgct ccaacatctc tccgccgccg tttcgggcgg
    40561 atactactac gcgccgtctg tcgaacgcct gcaaaacctc taagccggac gatgccgtct
    40621 gaaaccattt ttcagacggc attttcccgt tttatagtgg attaacaaaa accagtacgg
    40681 cgttgcctcg ccttagctca aagagaacga ttctctaagg tgctgaagca ccaagtgaat
    40741 cggttccgta ctatttgcac tgtctgcggc ttcgtcgcct tgtcctgatt tttgttaatc
    40801 cactataccg tccaaccgtt ttccgagcgc gcactatgtc tgcacccatc caagcattcg
    40861 actcgctaac cgtccccatt gccggcacca acctgattga ggcctctgcc ggcaccggca
    40921 aaacctacgg cattgccgcc ctgtttacgc gcctgatcgt attagaacaa aaaaacgtcg
    40981 agcgcgtatt ggtcgttacc ttcaccaaag ccgccaccgc cgagttgaaa acacgcctgc
    41041 gcgcacgttt ggacgatgtg ttgcaggttt tagaaagcaa agaaattgcc gaacttggag
    41101 acggcgcgct ttcagacggc atcgccgcct attgtgcgga acaccacaaa ggcgacacct
    41161 tcctgcccgc actcttaaaa caggctttgc aaaaagaggg ccggacgcgt ctgattgtcc
    41221 gcctcaaggc cgccatcggg caattcgaca acgccgccat ctacaccatc cacggcttct
    41281 gccagcgcat cctgcgcgac tacgccttct tgtgccaagc accgttcgat gtcgaactga
    41341 ccgaagaaga cggcgaccgc ctgcttatcc cggcgcaaga tttttggcgg gaacgcgtca
    41401 gcaatgatcc ggtgcttgcc gcattggcgt ttaaacgcaa agctgtgccg caaaccgtcc
    41461 ttgcccaaat ccgcgcctac ctgtcccgcc cgtacctgaa tttccgccgt ccgcaggcgg
    41521 atttgaaaca ggcgcagcgc aacgccgaaa cctcatggca aaccgtctgc cgcctgctgc
    41581 ccgagctgga agccggcttt tggcgcatcc atcccgacct caacggcaac agttaccgca
    41641 aaaacagctt cggcaacctt tttaaagaac tggcacaaaa atccgccgcc ggacaactgc
    41701 cctttctgga caaagacaca cacgacagac tcttgaaact tgcatccgac aaactcgaag
    41761 ccggactgaa aaaaggcaaa acgcccgatg cggcagtatt tgccgaattg cagaaactgg
    41821 cagacttcgg gcgcgatttg aacgcactcg aagaagcgga agaagcaaca atgatccggc
    41881 tgcaactgga tttaatcgaa tacctcaacc gcagccttgc cgagatgaaa aaatcgcgcc
    41941 gcgaacgcgg tttcgacgac ctgctgctcg atgtccacac cgcgctgacc gacaatccgc
    42001 acgccgaaac cctcgcccgc gccgttgccg aaaactggga aaccgcgctg atcgacgagt
    42061 tccaagacac cgacccgctg caatacgaaa tcttccaaaa aatcttcatc gcccaaaacc
    42121 gaccgctgtt cctcgtcggc gatcccaaac aggcgattta cagctttcgc ggagcggaca
    42181 tttacgccta ccttcaggcg gcggaagacg cgcggcaccg ctacacgctc gccaccaact
    42241 accgcagcca cgccgcgctt atcggcagca taggcgcgct gttccgcctc aaagaacgcc
    42301 cgttcgtttt ggaaaacatc ggctattcgg aagtcggtgc ggcgcgtgcc gaaagcagat
    42361 tgtcgcccaa acgtcctgcc gtacaggttc gttggctgca cgaaaacgac aatgaaaaag
    42421 ccaacaaaga cgttttgcgc cgccgtgccg ccgactattg cgccgacgaa atcgcccacg
    42481 cgctcaacga agccgccgaa tgccgtctga atttcaaagg ctgcccgttg cagtcgggcg
    42541 atattgccgt gctggtacgc acgcacaacg aggcggtgat ggtttccgcc gccctgaaaa
    42601 aacggcaggt gcaaagcgtc ctgctttcgc gcgaatccgt gttcgcctcg cccgaagccg
    42661 ccgccctgtc cgcactcatc ggcttctggc tcgaaccgca ccgcgccgga acgctgcgct
    42721 ttgtcctaac aagcggcata ttcggttatg acgcgcagca attgcacgac ttcaaccaaa
    42781 acgaaagcga gattttgcat tgggcggaat ctgcccgaac cgcgctcgac aactggaatc
    42841 aatacggcat tttcgccgcc atgcagcaat tttcccaaac acacggcatc gaaacacgcc
    42901 tcttaagccg gaacaacggg cgcagcctga ccaactattt ccaactgctc gaactgcttg
    42961 ccgccgaaga cgcgcaaaac cgcaaccccg ccgcgctgca caaatggctg cgcgaccaaa
    43021 tcagcctggc cggcaacaac ggcggcgaca accgcgccat ccgtctggaa agcgacgaag
    43081 atttggtcaa aatcgttacc atgcacgcct cgaaaggttt gcagtatccg ctggtgtact
    43141 gcccgtttgc gtgggacgcg caagataccg ggccgtccga ctggcaaatc ctccaccaaa
    43201 gcgcaaaccg aaccgaactg ttggcaaagg cgcaactgtc cgaagacgaa cagaaacaat
    43261 acgccgatga agaaatggcg gaacgcctgc gcctgcttta tgtcgcgctg acgcgtgccg
    43321 aggaacagct caacatctac gccgcgtact ccaccaatac tgccgacaac cccctcgcct
    43381 acctgattga aggctcgccc caagacagcc gtgaaaccgt ccgccgtgcc tatgcgtgtg
    43441 aaaaagacgg catcgcgatg ctcaaacgca actggcggcg cgtggcggac aacgcccctt
    43501 ccggcacaaa tttcgccttc acagaagatg cgccgccccc tgccgcctat cgcggcaacg
    43561 ccggtcaaac cgccgaattt gccgcaaaca gcattcccga acgcagattc cgatttgtcc
    43621 gccacaccag ctttaccgcc ttaagccgcc atacccaaac gcccgacggc ggcgaagaag
    43681 atgcctgccc gtccttggat gccgccgaaa tctcggtagc cgcgatgccg tctgaaacgc
    43741 cgacggcttc agatggcata tcgatacaca actttccgaa aggcacgcag gcggggctgt
    43801 gcctgcacga aattcttgaa gatttcaaat tcggacaagc agccgccgga caggaaaccc
    43861 tcatcaccga caagctgaaa aaatacggat ttgaagaaat atggctgccc gccgttgccg
    43921 aaatggcgga agcctgccgc aaaacgccgc tgacgggggc atacggcctg tccgacatcc
    43981 cgcccgagtg ccgctgtccc gaaatgggct ttaccctcca caccgaagac ttcggcctca
    44041 aacggctacg cgattggttt gcccgcgacg acatcaggct gcccgaagtc tgccgtgccg
    44101 ctgccgaaac gctagacttc cacaccgtca acggcttttt aaacggcttt atcgacatgg
    44161 tctgccaaga ccccgaggga aatatctgcg tcatcgacta caaatcaaac catctcggcg
    44221 cggacgcatc cgcctacacg cggcaggcga tggacgaagc cgtcgcgcac caccactatt
    44281 accttcaggc gctgatttac gccgttgccg ccgcacgcta cttcaaactg cgcggacaac
    44341 cgcccgccgc cgtttccgtc cgctacctgt ttttgcgcgg attggatggc aaaggcggcg
    44401 gcgtttggcg ttgggacata gatgccgccg ctttggaaca gataaaataa cttcccgtcc
    44461 tttcggacaa caaccgcagg agaaccctat gaatatcaaa cacctgatta ccaccgcact
    44521 cattgcctca gccgcctttg ccgcgcaggc agccccgcaa aaacccctat ccgccgccca
    44581 aaccgcgcaa catccggtcg tttggatcga tgtccgttcc gaacaggaat ttagcgaagg
    44641 gcatttgcac aacgcggtca acatccccgt cgaccaaatc gtccgccgca tacacgaagc
    44701 cgcgcccgac aaagacacgc cggtcaacct ctactgccgc agcggacggc gtgccgaagc
    44761 cgcccttcaa gaactgaaaa aagcaggtta tacaaatgtt gccaatcacg gcggttatga
    44821 agacctgctc aaaaaaggga tgaaatgacg caatgccgtc tgaaaggaca ggctttcaga
    44881 cggcatacgg cgttccggca cgcggcgcaa catcgggcgc ggcgcgcgcc gccccgtccg
    44941 aagcctgata aacaaaccga aaaggaaata cgatgaaaca catactcccc ctgattgccg
    45001 catccgcact ctgcatttca accgcttcgg cacatcctgc cagcgaaccg caaacccaaa
    45061 acgaaaccgc tatgaccacg cataccctca cctcaaaata cagttttgac gaaaccgtca
    45121 gccgccttga aaccgccata aaaagcaaag ggatggacat ttttgccgtc atcgaccatc
    45181 aggaagccgc ccgccgaaac ggcttaacga tgcagccggc aaaagtcatc gtcttcggca
    45241 cgcccaaagc cggcacgccg ctgatggtca aagaccccgc cttcgccctg caactgcccc
    45301 tacgcgtcct cgttaccaaa acggacggca aagtacgcgc cgcctatacc gatacgcgcg
    45361 ccctcatcgc cggcagccgc atcggttttg acgaagtggc aaacactttg gcaaacgccg
    45421 aaaaactgat acaaaaaacc gtaggcgaat aagcccgtcg ccgacatatg gcggatggaa
    45481 atcaaatgca cacgcccctc attcccacga agtcgggaat ccaatcggtt gggttaccgt
    45541 gattttcaat cattgcagaa acggacgact ccagattccc acccttgcgg ggatgacggg
    45601 cgtgtgtgtt tttgccacat cacaggcaac tttgccgcaa atcttatctg tcgccggtat
    45661 gccttcttgt ttcaatccgc cacaaaccaa atgccgtctg aaacccgatt tcagacggca
    45721 tttccgttta ttccctgctg tcgcggcaaa tatcaatggc ttcctgcaaa ctcgaaacgc
    45781 cgtagatttt caggttcgga aactctttgg cattgcgcgg catattggct ttgggaacga
    45841 tggcgcgttt aaagccgagc ttttccgctt ccttgagccg ctcttgtccg cgcgcgacgg
    45901 ggcggacttc accgctcaaa ccgatttctc caaatgcaac cattttttcg ggcagcgggc
    45961 ggttgcggaa gctggaaagc atcgcgagga tgaccgccaa atccgccgcc ggttcgccga
    46021 ttttcacacc gccgacggcg tttaaaaaca catcctgatc gaaacaggcg atgccgccgt
    46081 ggcggtttaa tacggcaagc agcatcgcaa ggcggttttg ttccagtccg acggtgaggc
    46141 gtttgggggt gaagccgtgt gcgtcatcga ccaatgcctg aatttcgacc aaaagcgggc
    46201 ggctgccttc ctgtgtaacc aaaacgcacg aaccgggcgt gtcgtcgcgg tagctggcaa
    46261 ggaagatggc ggacgggttg gacacgcctt tcaaaccgtt ttcggtcata gcgaacacgc
    46321 ccagttcgtt tgccgcgccg aagcggtttt tgatggcgcg tatcatgcgg tagttggaat
    46381 gttggtcgcc ctcgaaatac agcacggtat caaccatgtg ttccagcacg cgcgggccgg
    46441 caatcgcgcc gtctttggtc acgtgtccga ccagtatcat ggcgatgccc atctgtttcg
    46501 ccatgcgcgt cagttgggcg gcacactcgc gcacctgcga cacagaaccg ggggcggaag
    46561 tgatttggtc ggaatacatg gtttggatgg aatcgataac cacgacttcg ggctgatgct
    46621 gtttcaacgc tgcttgaatc gcttccatgc ggatttcggc aagcaggttc acgccttcgg
    46681 tgggcagttc caaacgctgc gcgcgcaggg cgacttgttg ggcggattct tcgccggaaa
    46741 cgtatagcac tttacggctt tgcgccattt tggcgatggt ttgcaacagc agcgtagatt
    46801 tgccgatgcc ggggtcgccg ccgagcagga tgaccgcacc atcgaccaaa ccgccgccca
    46861 atacgcggtc gagttcgccc atgccggtcg gattgcgcgg cacttcggtg gcggtcacgg
    46921 tggagaggga ctggacggtc gaggtatccg ccgcccaaga ttggaagcgg gcgtttttcg
    46981 gctcgggcgc ggcaaggctt tcctgaagcg tgttccactc gccgcaatgc gggcatttgc
    47041 cctgccattt cggggaagtg ccgccgcatt cggtgcattg gtaaagggtt ttaagcgttt
    47101 ttgccatcgg ttttccctgc atctgaaaac aaaaatgccg tctgaaatag ggacggttgg
    47161 gattacgcca atacggcaac accgccgccg tcatgtacta tccatacacg gcggatattg
    47221 ccgcattgcc ttatttttcc atccctcggc ttcagacggc atatcgggcg gtttcctgcc
    47281 ggcttacccg ccgtgatact gccgagacag ctcgtgtacg gtatcgacta agattttggc
    47341 gtgttcgggg tcggcgtgtt ggttgatgcc gtgtccgagg ttgaagacat ggccgctgcc
    47401 gtgtccgtag tcggctagga tacgtgcgac ctcggtgcgg atggattccg gcgtaccgaa
    47461 gagggcgaac gggtcgaagt tgccttgcag ggcgacttgc ttgccgacgc ggcggcgtgc
    47521 ttcgccgatg ttacacgtcc agtccaagcc caatgcgtct gcgccgattt gggccatact
    47581 ttccagccac agcccgccgc ctttggcaaa tacgataaca ggtacgcggc ggccttcgct
    47641 ttcgcgtttg agtccggcga cgatctggcg gatgtatttg aggctgaatt ctttaaacgc
    47701 cgcatcgctc aacacgccgc cccaagtgtc gaaaatctgc accgcctgcg cgcccgcgtc
    47761 gatttgggcg ttgaggtagg cggtaacggc ttgggcgttg gtatcgagga ttttgtgcag
    47821 caaatcgggg cgtgagtaca tcatggtttt gatggtgcgg aattctttgc tgccgccgcc
    47881 ttcgaccata taacaggcga gcgtgaacgg gctgccggag aagccgataa gcggtacgcg
    47941 gccgtccagt gctttacgga tggagctgac ggcatcaaag acgtattgca gtttttccat
    48001 atcgggaacg tgcagcttgg cgatatcggc ttcgtgttgc agggcgcgtt tgaatttcgg
    48061 gccttcgcct tcggcaaagt acagtcccaa gcccattgcg tctgggacgg tcaggatgtc
    48121 ggagaacaaa atcgccgcgt ccaaatcgaa gcgttccaaa ggttggatgg taacttcggt
    48181 cgccaatccg gtgtttttgc acaaatcgag gaagctgccc gctttcgcgc gtgtggcttt
    48241 gtattcgggc agataacgcc ccgcctggcg catcatccaa atcggcgtgt attcgacggg
    48301 ctgtttaagc agggcgcgga ggaaggtatc gttttttaaa agagtcatac gggttttctg
    48361 tcagtctgtt tgtcaagtga aatggttttc agacggcatt tcaacgatgc cgtctgaagg
    48421 tttcaatggg tttcggcgga aggtcggttt tcctcggcaa cgcttgccaa aaccaagttg
    48481 cgctgcgcct ccgccttctg cggttctccg gtttcgtcaa aaacctttgc cagaaccaaa
    48541 cgcgcggaaa tactcggctt taatgcaatg ctcgcttcaa ggtagccttt tgccttgccc
    48601 caaagtttgc ggccgtaggc gagccgaccg agatacatca gcagaagcgc gttatcgggc
    48661 tgttctttca gccaagcatc ggcaaaatcg atggctttct gctgttcgcg ttcgcccaaa
    48721 aagcgcacgc tttcgacaaa ggcttccaaa agctcggggc ggcggttgtg cggataatgc
    48781 tgtttgaccc atttgaccgc atcggcatac agtcccaaac gttcgtactt ttccgcaacc
    48841 gatacgctca attccccgtt tttgaggctg tcgggaatcc gcttcaggca ggttttcaaa
    48901 gcggcggcat cggcagcatc cgccagctgg cggcggtatg cccaattttg ataccgttcc
    48961 atttccgatt tgcccaacgc gcccgccttg gaaagttttt cggtttttgc cagaacctgc
    49021 aacgcgtcgc ccctgtcgaa agcgtaacga agttgcagac gcacgaggcg cgtaaggttg
    49081 gcattcatct tcgccgccgc atgaagattg gcttccgccg cttcgtaatc gcgccggttc
    49141 aacgccgatt ccgccaacaa aagataacgg gaaagctgct gcttttccgg cagtttggcg
    49201 atttccgcaa gataacggtc gcgcagctcg atgttttcca tctgcccggc ggcatgtgcg
    49261 cccaacatca atgccaaagt ccggttgtct ccggcctctt tgttgaccaa cacgcgtgag
    49321 gcttctagtt ccgccttttc aaaacgccct tcaaaatacg ccaaacccgc cttgttcaag
    49381 gcaagcgcgg ccttgcggcc tttacgcgcc gaaccgaaac gctgcatctt ttcggggata
    49441 ttgaatacgc cgataatgaa tttaaacagg aaataccaca ccacgacggc aatcagcgaa
    49501 cctaacacaa aggcgtgcag gttgattctg agcatggtct gtccgagtac gatatacacg
    49561 tcgccggtgt aaatgcccga agccaatgcc agcccgacgg cggcggcaaa caggacgaca
    49621 atccagacta ccgttttcat gcgcgttctc ctttagcgga cggcgaacgc cctgcctttt
    49681 ccggtacggg ctgttttttt gcaggctgtt ccggtttgcg ttccgaaggc agggacggtg
    49741 cttctatggt cttcacatcc gatgcggcag ccggttcgga agctgtgttt tcgtttgccg
    49801 gttcggaagc cgcctgttct gcttcttgat tttccgccgc cgtcatgcgc gtaccgtcgc
    49861 gataggcgcg gacggcattt aggctgtttt tcaaaccgtc atccgccgtc atgcgcacat
    49921 ccaacgcctt caattccgcc agttctttca gccacgactg cgtggcggga gacttggcat
    49981 cgaaatactg tctgacggcg gcttcggcat tgttcaaatc gccctgatag acttcgctgt
    50041 tgcgctgcat taatgcagtc cgcgcatcca aaaggcggag gcgcaggttt tcacgcacaa
    50101 aatatgcctg ttcgggagaa atcagcatgg catcgttgtt ttccaaacgg cggatttcga
    50161 ccagcccctt caatgtgccg agggattttt cccatacgtt ctgccaccat gaagcagaag
    50221 cggcttcgtt cttcacctgt acgcccggct tcaatacgcc gtccaaaatc agcggcagtc
    50281 cggatacggc ggtttccagc ctgtcgaggc gcaatgccgt gccggaaata tcgacatagg
    50341 gacggttttt cagttccgcc aagtcgctgc tgaccgcctg tttgatcggc agaagctctg
    50401 cctgattgaa acgggacagg cggctgtcga tatgctccaa tacgccgact gccgtttgga
    50461 tattgccggt caacaccagc tgttgcgccg ccagattgag tatggtctcg gtttcgtcca
    50521 ccagccaatc ggcgcgtcct ttggtcaact cgcgatagga tttttgcatt tccaagattt
    50581 gttcgccgtt tgctttgacg tttccgtcca aacggtcgag ttctgattgt atggcggctt
    50641 gccggttgag gttgtctttg agcagggcgg cgttttccga ctcgcccaag gcggctttgt
    50701 cgattttttg gttgaatgcc agctcttggt ttttcaagac attctgtcct tggacaaaca
    50761 aaaaaccact tgcgcccaaa cccaatgccg ccaataccaa ggcgcaggtt gccaaagcgt
    50821 tgttgccgga ctgtttgacg ataaaaggag cggcaggaat gtgtacttct gtttcgtttt
    50881 ctttgcgtgg ggaagaggtt tcagacggca tttcttttga tgcctgtatc tcgcgtacgg
    50941 gttcggatga tttgttttca ggttcgccca ccgttttgct ccttattaat ttgaggttcc
    51001 gggaaagacc atgccgtctg aaacggaaat ggaagaatgg gaaagcgcgg cttccagcgt
    51061 agggacggtt tcgaccgaac acacgccttc gcgcttcaat gcctccgcaa tgcgcggatg
    51121 atgggtaaag tatagcaagg atttgaagaa tcgggaaaat tgcggcggaa gctgcccgaa
    51181 cagcaagcgc accagctcgg tcgacgtaat ataggcggcg gcaatatttt cggtttggaa
    51241 attttgaaag ttcaaaggtt tatgccgtct gaaatagact tctgccacct ccgtccgaaa
    51301 acctttctcc tgcaaggcat tcatcaaaaa atcccgcccg ccgtgtccgc acacaaacaa
    51361 tacgcgcgca ccttcgggca gactgttcca aaccggcagg cgcaaaaccg cctcgctgtc
    51421 gttgccgtca tcaggcgcga tgaccgttct gaccaaacag cgttccaatg cgcggcggct
    51481 gccctgccct acggcaatct gcgcctttat gccgtctgaa aggttaaggt acgggacggc
    51541 ggtttcaacg gcggtcggac tgacccaaaa cacggcatcc gcacgggcat attgttcgga
    51601 caaaagttcc agtccggcag catctgcttc gatttcgacc ggactcaata cttccgcgcg
    51661 ccaaccggca ttcaggcaag tttcgacatc ttctgcggcc ctgcccgacg gacggacaat
    51721 cagcatgacg ggtttcgctg tttccatcgc cttatccgcc ccgattacta ggaaaaatcg
    51781 tcatcgttga aattcgcctg cgcggttttc ggcgtacagc cgacccgtgc gacttccttg
    51841 cccctacgct ccacaacgac accgctgctt tccgtatgag tcacggaatc gaagcctgtc
    51901 catatggtgt acataaattc gccgttttgg aatttcatcg ttgcccaacg accgctgccc
    51961 ataccttgcc acctgtcgga acgccccaac aggtcagctt tgctgttgcg tatggcaatt
    52021 tctttttttg ccgcactacc gaacgaatat tcgtaaagat tgcggttgat tttttgaact
    52081 tctatatatt tgttgttgtc cgttttacag gaaaacaccg tatccgccca cacggttcgg
    52141 gtcgcagccg acagaagcaa tacggcagaa aggaacattt ttttcatcgt atttccttaa
    52201 tggttgaaac tccgccattt ggacatccgt ccttcgtggc agcagcatca gatgttattt
    52261 gagaggggtg taaccccttc caaattaggg caacacatag ggcaacactt tatgtgtcgt
    52321 cctgtgtgtt gaaacatcat tgcccgtatc ctgaaataga aaagaaaatg cccgttttac
    52381 ggtcttcttt ccgacaaaat gccgtctgaa acggatttca gacggcatgg tcgaaaatta
    52441 ttgcgcggca agcggcttga gcagcaaggt ttcgccgctt tgcacaactt tttcaagcag
    52501 gtcgatattg ggatgcttgc cgggatgggc gcgcgcgtcg gcaacgtgtt cggcaaacca
    52561 tatcaaaccc tgttctgccg cttctttgtc caattttccg tcaaaacgtt ctgccaaagc
    52621 attgtacagc ttgagcgaac cgagcttacc ctgaacggcg ggaatgtggt gaaccgtttt
    52681 gccgtcggca tcctgaacgt ccaaaccgcc cagatggtcg attgaagaaa atgtggcgag
    52741 atagtcttgg aaattcatat caaatccgaa aatcagtcag ttagcgcgtg ccgaaaatct
    52801 tgtcgcccgc atcgcccaag ccggggatga tgtagccgtt ctcgttcaag tggctgtcga
    52861 gcgcggcggt gtaaatcgta acgtcggggt gcgcgtcgtt gaccgccttc acaccctcgg
    52921 gcgcggcaac cagcaccagt gccttgatgt ttttgcagcc cttggctttc aaaaggtcga
    52981 tggtggcaac catcgaaccg cccgtcgcca gcatcgggtc gataatcagg gcaggacgtt
    53041 cgtccatgct gtccacgaat ttctcgaagt aggaaacggg tttcagcgtt tcctcgtcgc
    53101 gctgcagtcc gactacgctg attttggcag tcggaatcag gtcgagtacg ccgtcaagca
    53161 tacccaaacc tgcacgcagg atgggaacga cggtcaatgt tttgcccttg atgcgatcgc
    53221 cttcaatctg accgcaccat ccgtcgataa ggtatttttc gatttcaaaa tcacggcttg
    53281 cctcgtatgc catcaggcgc gccagctcga tggcaagcgt ccggaatttg taggtgctgc
    53341 aatccgcctc cctcatcagg gttaatttgt ggcggacgag cggatggttg ataacattaa
    53401 cgttcatcgc ggtgttccag tgtgattttg agacgcgcca ttatactttt ttttgatttg
    53461 ccggaaaaga aaatgccgtc tgaaacacgt tcagacggca ttgccgaatc catcaggctt
    53521 tcagcagctc ttgcagctcg cctgcctcat acatttccat caggatgtcc gaaccgccga
    53581 caaactcgcc gttcacataa agttggggga tggtcggcca gtcgctgtat tccttaatgc
    53641 cttggcgtac ttcgggattt tccaatacgt tgacggtaac gtaatcggtg cagcccgccg
    53701 cgttcaggat ttgcacggcg cgggaagaga aaccgcattg cggaaactgc ttcgtacctt
    53761 tcataaacaa tacgacgcgg tgtgtcgtta ctacttcttt aatttggtcg tggatggaag
    53821 ccatcgctta ttccttttga taaagttgac aaaatttgtc aggtaggacg cattatacgc
    53881 aaaagcggaa acttcccaca atatttgccg tatatcgcgc agtatcaatg ttgtgaacgg
    53941 aaatattccc actcctcgac aatcctgctg tccggcaaat ggcacagggc atatccgccg
    54001 ccgctttcgt cttttttact tcccgtctgc cgcctttggc aatgcagaat ttggaagcgg
    54061 aatttgccat gcctgtccga aacgtgttgg caggcagccg gcagcagcgc ggacatacat
    54121 acggatgaat tgccttcatg gttttcctta tcgtcggcac agggtcagac ggtccgcata
    54181 tcgggtactt ttttaaacag ccggtaaaag ttttccgtcg tgtatgccgc aacctgttcc
    54241 aatgtttggt tccgcaattt ggcgatatgt tcggcggtat ggcgcacaaa agccggttcg
    54301 ttctgcctgc ctcgtttggg aacgggggcg aggaacggcg catcggtttc caccaaaatg
    54361 cggtcgtccg gcacatattt tgccgcctcc tgaaccaagg gtgcgttttt aaaggtaacg
    54421 attcccgaga aagaaatata aagccccaaa tccattgctg cacgggcaaa accgatgtct
    54481 tcggaaaaac agtggataac gcccgaatta acccggcatt ctttcaggat agacaaggtg
    54541 tccgccgccg catcacgcgt atggacgata acgggcagtc cggtttgatt ggctgcttcg
    54601 atgtggtctg caaagcgttt gtgttgccag gacaaatcgc ctttgcacca gtaataatcc
    54661 aaacccgtct cgccaatgcc gacctctttc ggcgaggcgg ctgcggcaac catttccgca
    54721 atagaaaatt cttcggcttc cttgctgtcg ggatgtacgc ctattgtgca gtaaatatgt
    54781 tcataaactt cggcgatagc ggatacttcg gcaaaacttt ccctgctgac gctgatggcg
    54841 agcgcctgcc ccacgccgtt tgcttccatg ttggacaaaa cttcgggcag gcgttctttc
    54901 aaaccttcaa aattgaggtg gcagtgcgaa tcgatgatat gcatggcgtt acatggtaaa
    54961 cgtaggtctg ctgccgccga ttgtgttgcc cagttcgact tcgatctggt ctttgacttt
    55021 caggcagttt tcgtgttttg tgaatgccag ccccacccct ttgggtttgg aggaagtacg
    55081 cgcaggattg atccaggcga ctttggtcgg caggaacagt ttggggaagt tgaggatttc
    55141 tacggcaagc agaatatcgt ccccgatgga aaatacgtcg ttggtctgca caaacagacc
    55201 gccgtgttcc aaaaacggca tgtaggagct gtacagcaga ttcatgtctt tcagctgcaa
    55261 cgacatcatt tttgccggaa tattttgtcc gtctgacata attcacccgt tctctttctt
    55321 caattccaaa tagttgatga gcagatgctc gatctgcatt ttgacattta aagtatgaaa
    55381 cccgtagggg gcaagctgtt tgagcatatc ctccgccgca aatacattgc gcaggcggaa
    55441 accggatgcc gtctgaagca gcctgtcttc ataagcggga taatagacgg gtttcatgtg
    55501 ttgcaggcac aatcccaaat cgaccagcca tttctgcatc cacccgacaa atacgtcgag
    55561 cggaagtttc tccttatcga aaagcgcggc gtaatccaaa atcttcaaca accttggttc
    55621 tgccaaaata tccaacagtt taatccgcaa cgcacggaca ccgtccgcct catcaaacag
    55681 cggcgctccg gaatggaaag ccagacgttc ctcaggttcc gccacacccc tttcacgcag
    55741 atatgccaat gcctcttcat gggaaggcgc gggcaaaacc atcttccggc agcggctttt
    55801 aatggtcggt aaaaccttgt ccgccgcgtg gctgaccagc aaaaagacca cttgtggcgg
    55861 cggctcttcc aacactttca acaaactgtt ggcggcttgg acattcatac tttccgcagg
    55921 atgaatcaga atcacgcgca aaccgccccg taccgaagtc aggtacacat tatcgatgat
    55981 ttccctgacg gcatcgattt tgatctgcaa cagtttgcgt ccgttttcgg gttcgtccga
    56041 caagggggtg atttcgtaaa aatcgggatg gcttccctgt ccaaacagat ggcaggacat
    56101 acattcgcca cagggtttgc agcccggtgc aggggtttcg cacaacagtg ccttcgccgc
    56161 aaagcgggca aatgtagttt tccccgtatc ttttttgccg gcaaacagcc atgcattggg
    56221 acgacgctcc caatgttccg caatctgccg ccattgctca ttatgccacg gataaatcat
    56281 ttcaaaccat ccgtccggaa atccataccg ccatcagagc agttccaaat cggggctgga
    56341 actttgcgcg cggcggctgc gcaactgtac cgccaaacgc aaatcgtgtg cggaatcggc
    56401 atttttcaat gcttcttgca gggaaatatc gcctttttca tacaattggt aaaggtgttg
    56461 atcgaaggtc tgcataccca gggtagtgga ttttttcatc acttctttga tttcatggat
    56521 gttgccgttg tgaatcaact ccgaaatcag gggcgaattg agcagcacct cgactgccgc
    56581 caccctgccc ttgccgccgt ctcgcggaac gaggcgttgc gaaataaacg cctgaaggtt
    56641 gagcgacaaa tccgtcagca attgttcgcg ccgctcctcg gggaaaaagt tgatgatgcg
    56701 gtcgagtgcc tgattggtgc tgttggcgtg cagcgtcgcc atacacaaat gccccgtttc
    56761 ggcaaaggca atggcgtagt ccattgtttc gcggtcgcgg atttcgccga taaggatgac
    56821 atccggcgcc tgacgcagcg tgtttttcaa cgccgccatc cagttttccg tatccacgcc
    56881 gacctcgcgc tgggtgatga tgcagttttt gtgttcgtgg acaaactcga tcgggtcttc
    56941 gatggtgatg atgtgtccga acgaattttc attgcggtaa tcgataagcg aggcaagcga
    57001 agtcgatttg cccgagccgg tgccgccgac aaaaataacc agcccgcgtt ttttcagcgc
    57061 gacatccttc aagaccggcg gcaggttcag gctttcaaac ttgggaatct tgctggtaat
    57121 cgcacggaat accaacgccg tcgcgccgcg ctgtatcatc gcattgacgc ggaagcggct
    57181 ggtgtccggc aggctgatgg cgaagttgca ctcgttggtc gatgaaaatt cttccgcctg
    57241 cttcgcactc ataatcgaaa aggcgatttc catacatttt tccgccgtca gcggttcgtc
    57301 cgtgatgcgg gtgattttgc cgtccagctt cattgcgggc gggaaatggg tcgtcacaaa
    57361 caggtcggaa cctttgtttt tgttcatatg gcgcagccat gcgaacagtt cttcctttgc
    57421 ggtcatattt tcatcggtaa acatcctcgt cccctaatct tcaaacaatc tgtaccttcc
    57481 cattctacca aaaacccgcc gtgccgtctg aaaccgtttc agacggcacg gacaaaccgc
    57541 ccccactcaa tcctgccgtg ttagcgtgta taatccggca ttctatccga aattcacaac
    57601 aggtcagcaa tatgtctttg aaaacagtag ccgttatcgg cgcaatggaa caagaaatca
    57661 agcttttgcg cgagatgatg gaaaatatca aagccgtctc tttcggcaga ttttccgcct
    57721 atgaaggcga attggtggga aaacgcatgg tgcttgcatt gagcggcatc ggcaaggtca
    57781 acgcggcggt tgcaacggct tggcttatcc atcaattcgc accggactgc gtcatcaaca
    57841 ccggcagcgc gggcggtttg ggcaagggtt tgaaagtcgg cgacgtagtc atcggtacgg
    57901 aaaccgcaca ccacgatgtc gacgtaaccg cattcggcta tgtttgggga caagtgccgc
    57961 aactgccggc aaggtttgct tcagacggca ttttgattga ggcggcaaaa cgggcggcgc
    58021 ggacgtttga aggcgcggcg gtagaacaag gcctgattgt cagcggcgac cgcttcgtcc
    58081 acagcagcga aggcgtggcg gaaatccgca agcacttccc cgaagttaag gcggtagaaa
    58141 tggaagcggc ggcaatcgcc caaacctgtc atcagttgga aacgcctttc gtcatcatcc
    58201 gcgcggtttc cgattcggca gacgaaaagg cagacatcag ctttgacgag ttcttgaaaa
    58261 cggcggcggc aaattccgca aaaatggtgg cagaaatcgt caaatcttta taaaaccttt
    58321 atcaaatcat gccaaaacag cggttttccg ttagaatatc gggctatttc cacgttgcgc
    58381 ccgatatttg gacgtaccgc tgtttgttca gacggcattt ctaaaaccta ccgttcagca
    58441 ttaaaaacaa ctcaatgaaa aatatccgaa atttctccat cattgcccac atcgaccacg
    58501 gcaaatcgac gcttgccgac cgcttcatcc aatattgcgg cggtttggat ttgcgcgaaa
    58561 tgagtacgca ggtactcgat tccatggaca tcgaaaaaga gcgcggcatt accattaaag
    58621 cgcaaaccgc cgcgctcaac tataaagcac gcgacgggca ggtgtatcaa ctcaacctga
    58681 ttgacacgcc gggacacgtc gacttctctt acgaagtctc tcgttcgctc tctgcctgcg
    58741 aaggcgcgct tttggtcgtt gacgcgtcgc agggcgtgga agcgcaaact gtggcgaact
    58801 gctataccgc gattgatttg ggcgtggagg ttgtgcctgt tttaaacaaa atcgacctgc
    58861 ccgccgccga ccccgaacgc gtggaacaag aaatcgaaga cattatcggc atcgatgccg
    58921 tcggtgcggt gcaatgttcc gccaaaagcg gcatcgacgt ggaagacgtt ttagaagaaa
    58981 tcgttgccaa aatccctgcg ccgaccggcg acgaaaacgc gccgctgcaa gccgtgatcg
    59041 tcgattcgtg gtttgacaac tatgtcggcg tggtcatgct gattcgagtg aaaaacggca
    59101 ccatcaaact gaaagacaaa gtgcgcttta tgagcaccaa ggcggaaacg caggtcgagc
    59161 agctgggcgt attcacacca aaatcagttc aaaaacaaga actcaaagcc ggcgaagtgg
    59221 gctttttgat tactggcgta aaagaattgg gtcaggcgaa agttggcgat acggttacac
    59281 tggttgccaa ccctgccact gagccgctgc ccggcttcca agaagtacaa agccaagtat
    59341 tcgccggact ttatcccgtg gaaagccacg actacgaagc cttgcgcgac gctttggaaa
    59401 aattgcagct taacgacgct tcgttgaaat tcgagcctga agtttcccag gcattgggct
    59461 tcggcttccg ttgcggcttc ttgggtctgc tgcacttgga aatcgtgcag gaacgtttgg
    59521 agcgcgagtt cgacatggac ttgattacca ccgcgccgac ggtggtttac gaagtcgtgt
    59581 tgaaaaacgg tgagaaaatc gaagttgaaa acccgtccaa actgcccgac atcggcagca
    59641 tcgaaaccat actcgagccg attattaccg cgaccatcct cgtgccgcag gaatacgtcg
    59701 gcaacgtcat gactttgtgt aaccaaaagc gcggcgttca ggtcaatatg caatatatgg
    59761 gccgccaagt catgctgact tacgatttgc ccatgaacga agtcgtcatg gacttcttcg
    59821 acaaactcaa atccacttcg cgcggttatg cttcgttgga ctaccatttc aaagagttcc
    59881 aaccgtctga tttgattaag ctggatatca tggtcaacgg cgaaaaagtc gatgccttaa
    59941 gcctgattgt gcaccgtcaa agcgcggttc accgaggccg cgagctggca tcgaaaatgc
    60001 gcgagctgat tccgcgccaa atgttcgaca ttgccgtcca agccgccatc ggcagccaga
    60061 ttatcgcccg cgaaaacgtc aaagcactgc gtaaaaacgt cttggcgaaa tgttacggcg
    60121 gcgatattac gcgtaagaaa aaactgcttg aaaaacaaaa ggcaggtaaa cgccgtatga
    60181 aacaagtggg caatgtggaa atcccgcaaa gcgcgttctt ggcgattttg caggtgagcg
    60241 acaaataata tttcggcaca tagggcggcg cgtcgggaac acctctcaaa ccgccctgat
    60301 ttcaggggca cgcgcccgca aacaaatttt gcaatttgcc gccttaaaac ggttgcacgg
    60361 ccgggcgggt ttttaaccgt tgaggaacaa caatgaacac aatgctaatg tcgggcgcgg
    60421 ctgccgcgct gcttgccggc atcatccttt atttcaaaag cgacaagaag cggcaggaaa
    60481 acggtgaatg gagttccggc ctcgaatacg cctatatcct gacggcggtc ggcgtgtttg
    60541 ccgctttgtc cctgtttatg agctttgccg ccgttttcct gattttcgtt gtattgtgcg
    60601 gtacggcttg ggcggtatac aaataccgcc tgaagactca tcccgaaatc tcggaaagca
    60661 gccacttcgg cgattatttc ggcagtttct tccctaccgt tttggtattg ttcctcatcc
    60721 ggtcgtttat tgccgaaccg ttccaaatcc cgtccagctc gatgcgcccg ggcctgatta
    60781 agggcgattt cattttggtc ggcaaatttt cctacggtct gcgcgtaccc gttttaaaca
    60841 atatatttat tcctacaggc aaaatcgaac gaggcgatgt cgttgttttt aattatcctc
    60901 tgcagccgga gatgacctac atcaagcgta ttgtcggcat tccgggcgat gtggtcgaat
    60961 atcgggataa gattttgacg gtaaatggca aacccacttc cgatattcct aacggcacat
    61021 accgttatcc cgacgacacc gacccttccg aaatccacaa cacggatatg ttccgcagcg
    61081 atctggacgg caaatccttc aatattctga aaaaagaagg acagcctgcc gtttccctgc
    61141 ccgtattggg caaatatacc tccgatatta tgtctgaaaa cggatattcc atagagcaaa
    61201 gcggtttgga acactgccaa tatgccgacg acggcagcgg tttcgtgtgc aaagttcccg
    61261 aaggacgcta tttcgctatg ggcgacaacc gcgacaacag tgccgattcg cgctactggg
    61321 gatttgtgga tgacaagctg gttgtcggca aggcaatgtt cattttgatg aacttcggcg
    61381 atttcggcag gtccggtacg gcaatccgtt aggccggaaa attacgccgg aacatcaaaa
    61441 atgccatccg aaccctgttt cagacggcat ttttatcatc aaacgccttg tttccctgcc
    61501 ggcagcctcg gggataatat agtggattaa atttaatcca ctatatttcc gtttgtgtgg
    61561 aaacccatcc cattgaataa agggcatttc gtccgactga cggtgtgggc ggcagcggag
    61621 gcggcttttt tgattctgcc cgccccgatg ccgtctgaaa gggcttcaga cggcattttc
    61681 cgctccgcgc cgttgctggc gtgtttggtc ttgccggttt tgactgcctg ccagttcaat
    61741 cgtacgcagg tttgccacgg cagaaaatct gatgccggac ggagtcaagg ctcggactgc
    61801 tgtttcagcg aaccgaggta aattgccgaa agcgtcagcg ccacccctgc ccactgcacg
    61861 ccttcaatcg gtttgcccaa cccgaaataa tcgatgaaca gggcggcaac cggttcggac
    61921 aaaagcagca gccccgtcag cgacagcgaa agcagcggaa tcgcataggc aaccatcgcc
    61981 cacgcgaagc actgcatcac cacgccgtac acaagcacca aacccgcatc tttccaagtc
    62041 gtcggataaa gcacgccgcc atccatcagc aatgccggaa caaccagcga taccgcgccg
    62101 cccaaactca aaatcatcat tgaagggaaa agcgccaccg gctcgatttc atgggttttg
    62161 cggacgaaca ccatcgacag ggcgagcatc agtcccgata ccaaaccgct ggcgaatccc
    62221 caaaccgcat taccgttgta gccgaattcc gcaccggcaa tcatcgccac gccggcaact
    62281 gccgatatta agcctgcctt tttcagcccg ctcaaacgtt cgttaaaaaa gaaaacaccg
    62341 attgccgaca agaaaaagat ttgcaggctg ttgagcaggg tggaaatacc cggcccgacc
    62401 gcgtgtatgc tttcgtgcca caacgccaaa tcgaaagcga ggaacacgcc cgccgtcagg
    62461 gcatatcgga cggttttcct gttttttggg aatttttgcc cgaaaaaccg tgccaaaaac
    62521 caaaatacga acaccgaaat cagcaaccgc caaaatgcga ttgcatacgg gccgacgggg
    62581 acggacctga caatcagact gcccagaccg aacaccacgc aacccagcac cagcaatggt
    62641 gcggcatatt ttttgccgtt accgaccaca atatcccctc ccttccccat acggctgccg
    62701 cgccgacggc aagaatgccg ccattccgaa aatatgccgt ctgaagccca aagccccggc
    62761 tgcacccgga caaacggctg attttacggg caggccgact attttccgtt ggggcaaaaa
    62821 accgtcctgc cagataaaac ccgaatatag tggattaaca aaaaccagta cagcgttgcc
    62881 tcgccttagc tcaaagagaa cgattctcta aggtgctgaa gcaccaagtg aatcggttcc
    62941 gtactatttg tactgtctgc ggcttcgttg ccttgtcctg atttttgtta atccactata
    63001 aaaaa
//
LOCUS       DAXISH010000005        59152 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.005, whole genome shotgun sequence.
ACCESSION   DAXISH010000005 DAXISH010000000
VERSION     DAXISH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 59152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59152
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.005"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(99..2075)
                     /locus_tag="ACFOV4_000294"
     CDS             complement(99..2075)
                     /locus_tag="ACFOV4_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFC7618384.1"
                     /translation="MNEFSLAPIVVVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPG
                     MLSLIPKSHATDYLGEIGIVFLMFSIGLEFSLPKLRAMRRLVFGLGGLQVGVTMLSVM
                     GILMLTGVPFNWAFAVSGALAMSSTAIVSRILSEKTELGQPHGQMAMGVLLMQDIAVV
                     PLMILIPALAGGGDGNIWAALGLAFAKMLLTLGLLFFVGSKIMSRWFRMVAKRKSSEL
                     FMINVLLVTLGVAYLTELEGLSMALGAFVAGMLLSETEYRFQVEDDIRPFRDILLGFF
                     FITVGMKLDIQALIGGWRQVLMLLAMLLVLKALVVFAIAFKMKHSVGDSLKTALYLAQ
                     GGEFGFVMLAIAGQLDMVSPEWEQAATAAVLLSMIIAPFLLGGSDALVGRLVKSSWDM
                     KSLDLHSMLVETMSKSDHVLIVGFGRGGQTVGRVLAQEDIPYFALDLDIARVQVARSA
                     GEPVSFGDAKRREVLEAAGLGRAKMVVLTLNNMHETQHVLDNVLSMYPNMPVYVRATN
                     DDYVKTFTDIGAEEAVSDTKETGLVLAGYAMLGNGASYRHVYQTMANIRHSRYAALEG
                     LFVGSDDEAGFGENGETVRHAFPLAAEAYAVGKTVGTLPMAAYGIKLLFVRRRTGRIE
                     NPDASFTLKGGDVLVVAGKKEEIISFENWSLQGI"
     gene            2224..3063
                     /locus_tag="ACFOV4_000295"
     CDS             2224..3063
                     /locus_tag="ACFOV4_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HFC7618385.1"
                     /translation="MTATAAAIDRLLPQTQCRECGYDGCLPYAQAVATGEAYNLCAPG
                     GEAVIRDISALLGKPLVAPAKTQAKALAQIDETACIGCTACIRACPADAIMGAGKLMH
                     TVIADECTGCGLCVAPCPVDCIHMQPVADTVLPRARRFSLSADSRFAAAEHARARYLK
                     RNERKQREADERKAMLAEREAAVRNARPQTPDTPKKPAFNPADLIAKAMAKAQTQQDR
                     LAAADNRKDYQAKQIAEARERAELRRAQRDMKYGSDSEKAAALEYLKQYKAKQEAAQN
                     TAS"
     gene            3263..4294
                     /gene="gap"
                     /locus_tag="ACFOV4_000296"
     CDS             3263..4294
                     /gene="gap"
                     /locus_tag="ACFOV4_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFC7618386.1"
                     /translation="MGIKVAINGYGRIGRQVLRAIYDYQIQDQLQIVAVNASGSLETN
                     AHLTKFDTVHGRFEADVSHDGGNLIVNGDKIPFFSTRNPAELPWKELGVDLVMECTGA
                     FTSKEKAKVHLESGAKKVLISAPGGDDVDATVVYGVNDSVLTADMTVVSNASCTTNCL
                     SPVAKVLSESVGIVKGAMTTIHALTNDQTVTDVRHKDLRRARSGVENMIPTKTGAAKA
                     VGLVLPELKGRLDGLAIRVPTVNVSLVDLNFQAARDTTIEEINALMKAASEAGALKGV
                     LGYNTLPLVSMDFNHTTEASHFDATLTKVVDGNMIKVFAWYDNEWGFSCQMLNTARRM
                     FGLEVRPLK"
     gene            complement(4548..5273)
                     /gene="aat"
                     /locus_tag="ACFOV4_000297"
     CDS             complement(4548..5273)
                     /gene="aat"
                     /locus_tag="ACFOV4_000297"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008914 - leucyl-tRNA--protein transferase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HFC7618387.1"
                     /translation="MRIPLLAPDNYAFPDPAYALARCDGLVGVSGDLDAGRLLEAYRN
                     GVFPWFSRDGWFFWYAVGPRAVIVPERLHVPRSLAKTLRNGSYRVAVNGCFAEVVAHC
                     AAAARPNQDGTWIAPEFQTAYLKLHEMGHAHSFECHYPDESGETRLAGGFYGVQIGSV
                     FYGESMFALQPDASKIAFACAVPFLADLGVELIDCQQDTEHMRRFGSELLPFADFAER
                     LRMLNAVPLKEEIGRREVACKGL"
     gene            complement(5343..5777)
                     /gene="fur"
                     /locus_tag="ACFOV4_000298"
     CDS             complement(5343..5777)
                     /gene="fur"
                     /locus_tag="ACFOV4_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HFC7618388.1"
                     /translation="MEKFNNIAQLKDSGLKVTGPRLKILDLFETHAEEHLSAEDVYRI
                     LLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDHIVCVKCGEVT
                     EFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR"
     gene            5996..6373
                     /locus_tag="ACFOV4_000299"
     CDS             5996..6373
                     /locus_tag="ACFOV4_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HFC7618389.1"
                     /translation="MNKTLILALSALLGLAACSVERVSLFPSYKLKIIQGNELEPRAV
                     ASLRPGMTKDQVLLLLGSPILRDAFHTDRWDYTFNTSRNGIIKDRSNLTVYFENGVLV
                     RTEGNALQNAAEALRVKQNADKQ"
     gene            6383..7192
                     /gene="dapB"
                     /locus_tag="ACFOV4_000300"
     CDS             6383..7192
                     /gene="dapB"
                     /locus_tag="ACFOV4_000300"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFC7618390.1"
                     /translation="MTPLKIAIAGANGRMGRVLVEAVNNHPDTVLSGALEHSGSEALG
                     LDAGYAVGLKTGIAISDDVDAVLAQSDVLIDFTRPEPTLKHLQKCVEKQVNIIIGTTG
                     FDDAGKAAIHTAAEQTGIVFAANFSVGVNLTFHILDTVARVLNEGYDIEIIEGHHRHK
                     VDAPSGTALRMGEVIAGALGRDLKQCAVYGREGHTGPRDPSTIGFATVRAGDIVGDHT
                     ALFATDGERVEITHKAGSRMTFAAGAVRAAVWVNGKTGLYDMQDVLGLNNR"
     gene            complement(7456..7866)
                     /locus_tag="ACFOV4_000301"
     CDS             complement(7456..7866)
                     /locus_tag="ACFOV4_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618391.1"
                     /translation="MTTYTIPKKDYQFLYIYEGTLLNYTLKNDEFHIIVQNVDYPDFP
                     QEIPMPNYSEWVKIKFKQFSYLKFIYGYATKNQDKNIKNVLELGELKQDDEILDYGGA
                     LEVIGGRYDLPTGFSIDIVCREIELEFLDQESFN"
     gene            complement(7868..8113)
                     /locus_tag="ACFOV4_000302"
     CDS             complement(7868..8113)
                     /locus_tag="ACFOV4_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618392.1"
                     /translation="MDYFPEAARITKKGGEIVINGTSNNKYLRGIPNEAELARVGLRL
                     KYNGLLKEEFKQLKFHKSSRTNLDSKNLKLIVFEKVK"
     gene            complement(8121..9293)
                     /gene="lpxB"
                     /locus_tag="ACFOV4_000303"
     CDS             complement(8121..9293)
                     /gene="lpxB"
                     /locus_tag="ACFOV4_000303"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008915 - lipid-A-disaccharide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HFC7618393.1"
                     /translation="MWGQTNMADKKSPLIAVSVGEASGDLLGAHLIRAIRKRCPQARF
                     VGIGGELMKAEGFESLYDQERLAVRGFVEVVRRLPEILRIRRGLVRDLLSLKPDVFVG
                     IDAPDFNLGVAEKLKRSGIPTVHYVSPSVWAWRRERVGKIVHQVNRVLCLFPMEPQLY
                     LDAGGRAEFVGHPMAQLMPLEDDRETARQTLGVDAGIPVFALLPGSRVSEIDYMAPVF
                     FQTALLLLERYPAACFLLPAATEATKRRLAEVLQRPEFAGLPLTVIDRQSETVCRAAD
                     AVLVTSGTATLEVALCKRPMVISYKISPLTYAYVKRKIKVPHVGLPNILLGKEAVPEL
                     LQSEAKPEKLAAALADWYEHPDKVAALQQDFRALHLLLKKDTADLAARAVLEEAGC"
     gene            complement(9341..10333)
                     /locus_tag="ACFOV4_000304"
     CDS             complement(9341..10333)
                     /locus_tag="ACFOV4_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFC7618394.1"
                     /translation="MKTHEISKDSVSLIGVAEHEAGQRLDNYLIKILKGVPKSHIHRI
                     IRAGEVRLNKKRCKPDSRIAEGDTVRIPPVRVAEKEMPSERRAAVPARAFDVVYEDDA
                     LLVIDKPSGVAVHGGSGVSFGVIEQLRRARPEAKYLELVHRLDKDTSGLLMVAKKRSA
                     LVKLHEAIRNDHPKKIYLALGVGKLPDDNFHVKLPLFKYTGAQGEKMVRVSEDGQSAH
                     TVFRVLSRFSDGILHGVGLSHLTLVRATLKTGRTHQIRVHLQSQGCPIAGDERYGDYQ
                     ANRRLQKLGLKRMFLHASELHLNHPLTGEPLVLKAELPPDLAQFAVMLENGTKM"
     gene            10828..13584
                     /locus_tag="ACFOV4_000305"
     CDS             10828..13584
                     /locus_tag="ACFOV4_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HFC7618395.1"
                     /translation="MKRMLFNATQAEELRVAIVDGQNLLDLDIETLGKEQRKGNIYKG
                     IITRIEPSLEACFVDYGTDRHGFLPFKEVSRSYFQDYEGGRARIQDVLKEGMEVIVQV
                     EKDERGNKGAALTTFISLAGRYLVLMPNNPRGGGVSRRIEGEERQELKAAMAQLDIPN
                     GMSIIARTAGIGRSAEELEWDLNYLKQLWQAIEEAGKAHHDPYLLFMESSLLIRAIRD
                     YFRPDIGEILVDNQEVYDQVAEFMSYVMPGNIGRLKLYEDHTPLFSRFQIEHQIESAF
                     SRSVSLPSGGAIVIDHTEALVSIDVNSARATRGADIEDTAFKTNMEAAEEVARQMRLR
                     DLGGLVVIDFIDMENPKHQRDVENVLRDALKKDRARVQMGKLSRFGLLELSRQRLKPA
                     LGESSHVACPRCAGTGVIRGIESTALHVLRMVQEEAMKDNTGEVRAQVPVDVATFLLN
                     EKRAELFAMEERLDVNVVLIPNIHLENPHYEINRIRTDDVEEDGEPSYKRVAEPEEDE
                     SAKPFGGEKAKAARPEPAVKGVRHTSPAPTAAPEKKTSWWDSFKAWLKRIFGGSETQA
                     APAAETSEKRSTANRSGSRANNRRQNPRRSKREGSKVEVREVAGKTAGQEARADKAET
                     RNNGNRRRNERGDRAAERANEAEIQDRNIQPAATVADAAPSETEVQTGKRRRNGSRNE
                     RGQTALETAAVAETAVQTAENTPSEPHTAEDKGSKPKSERNRRERDSRDAKERRERNN
                     QRDRRQNGKKRNIPSAAKIEQYLNIHDTADKVRSAAAHVFGETDANAPITVSIADPLI
                     ATPVQTASSAVSNGDALVYDAAEKIRRAAAILPEGATPKASAQEMPSETATFTAAAEQ
                     ARETAQTGGLVLIETDPAALKAWAAQPEVQTGRGLRRSEQPKPSEAATVPAEEMIQVE
                     TRQG"
     gene            complement(14362..15354)
                     /gene="pdxA"
                     /locus_tag="ACFOV4_000306"
     CDS             complement(14362..15354)
                     /gene="pdxA"
                     /locus_tag="ACFOV4_000306"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HFC7618396.1"
                     /translation="MKQPVFAVTSGEPAGIGPDICLDLAFARLPCRCAVLGDKNLLRA
                     RAEALGKSVVLRDFDPESGGAPGEGELEVLHIPTAEAVAAGRLNPANAAYVLQLLDTA
                     LAGISDGIFDGIVTAPLHKGIINDARASTGFFSGHTEYLAEKSGTGQVVMMLAGKGLR
                     VALVTTHLPLKDVAAAITQPLIESVARILHHDLKHKFGIKNPKILVAGLNPHAGESGH
                     LGHEETDTIIPALENLRREGINLAGPYPADTLFQPFMLEGADAVLAMYHDQGLPVLKY
                     HSFGQGVNITLGLPFIRTSVDHGTALDLAATGRADSGSLITAVETAVEMARGSL"
     gene            15514..16941
                     /locus_tag="ACFOV4_000307"
     CDS             15514..16941
                     /locus_tag="ACFOV4_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFC7618397.1"
                     /translation="MNENFTEWLHGWVGAINDPMWSYLVYMLLGTGLFFTVTTGFVQF
                     RLFGRSIKEMLGGRKQGDDPHGITPFQAFVTGLASRVGVGNIAGVAIAIKVGGPGAVF
                     WMWVTALIGMSSAFVESSLAQLFKVRDYDNHHFRGGPAYYITQGLGQKWLGVLFALSL
                     IFCFGFVFEAVQTNTIADTVKAAWGWEPHYVGVALVILTAPIIFGGIRRISKAAEIVV
                     PLMAVLYLFIALFIILTNIPMIPDVFGQIFSGAFKFDAAAGGLLGGLISQTMMMGIKR
                     GLYSNEAGMGSAPNAAAAAEVKHPVSQGMIQMLGVFVDTIIVCSCTAFIILIYQQPYG
                     DLSGAALTQAAIVSQVGQWGAGFLAVILFMFAFSTVIGNYAYAESNVQFIKSHWLITA
                     VFRMLVLAWVYFGAVANVPLVWDMADMAMGIMAWINLVAILLLSPLAFMLLRDYTAKL
                     KMGKDPEFKLSEHPGLKRRIKSDVW"
     gene            17266..19161
                     /gene="mnmG"
                     /locus_tag="ACFOV4_000308"
     CDS             17266..19161
                     /gene="mnmG"
                     /locus_tag="ACFOV4_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFC7618398.1"
                     /translation="MTHMIYPKTYDVIVVGGGHAGTEAALAAARMGAQTLLLTHNIET
                     LGQMSCNPSIGGIGKGHLVRELDALGGAMALATDKSGIQFRRLNASKGAAVRATRAQA
                     DRILYKAAIREMLENQENLDLFQQAVEDVTLDGDRISGVITAMGVEFKARAVVLTAGT
                     FLSGKIHIGLENYEGGRAGDPAAKSLGGRLRELNLPQGRLKTGTPPRIDGRTIDFSQL
                     TEQPGDTPVPVMSVRGNAEMHPRQVSCWITHTNTQTHDIIRSGFDRSPMFTGKIEGVG
                     PRYCPSIEDKINRFADKDSHQIFLEPEGLTTHEYYPNGISTSLPFDIQIALVRSMKGL
                     ENAHILRPGYAIEYDYFDPRNLKASLETKTIAGLFFAGQINGTTGYEEAAAQGLLAGA
                     NAVQYVREQDPLLLRREQAYLGVLVDDLITKGVNEPYRMFTSRAEYRLQLREDNADMR
                     LTEDGYKIGLVGEAQWRMFNEKREAIEREIQRLKTTWYTPQKLAEDEQIRVFGQKLSR
                     EANLHDLLRRPNLDYAALMTLEGAMPSERLSAEVVEQVEIQVKYQGYIDRQNEEIDSR
                     RDIETLKLPEDIDYSKVKGLSAEVQQKLNQHKPETVGQASRISGVTPAAVALLMVHLK
                     RGFKDAK"
     gene            19229..19813
                     /gene="rnhB"
                     /locus_tag="ACFOV4_000309"
     CDS             19229..19813
                     /gene="rnhB"
                     /locus_tag="ACFOV4_000309"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFC7618399.1"
                     /translation="MHILTAGVDEAGRGPLVGSVFAAAVILPEIFDLPGLTDSKKLSE
                     KKRDALAEMIKNQAVAWHVAAASPEEIASLNILHATMLAMKRAVDGLAVRPERIFIDG
                     NRIPEHLNIPAEAVVKGDSKIIEISAASVLAKTARDAEMYALAQRHPQYGFDKHKGYG
                     TKQHLEALKQYGVLPEHRRDFAPVRNLLAQQALF"
     gene            complement(20486..21259)
                     /locus_tag="ACFOV4_000310"
     CDS             complement(20486..21259)
                     /locus_tag="ACFOV4_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFC7618400.1"
                     /translation="MSANILAIANQKGGVGKTTTTVNLAASLASRGKRVLVVDLDPQG
                     NATTGSGIDKASLQSGVYQVLLGDADVQSAAVRSKEGGYAVLGANRALAGAEIELVQE
                     IAREVRLKNALKAVAEDYDFILIDCPPSLTLLTLNGLVAAGGVIVPMLCEYYALEGIS
                     DLIATVRKIRQAVNPDLDITGIVRTMYDSRSRLVAEVSEQLRSHFGDLLFETVIPRNI
                     RLAEAPSHGMPVMAYDAQAKGTKAYLALADELAARVSGK"
     gene            complement(21358..21981)
                     /gene="rsmG"
                     /locus_tag="ACFOV4_000311"
     CDS             complement(21358..21981)
                     /gene="rsmG"
                     /locus_tag="ACFOV4_000311"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFC7618401.1"
                     /translation="MERKERLQSGIAAMGLDISETAQDRLLAYVDLLKKWNKTYNLTA
                     LRDEEKMIVHHLLDSLTLLPHIEGVQTMLDVGSGGGQPGIPAAVCRPDVQITLLDANT
                     KKTAFLQQAVIELGLDNVRVVSGRVEAVSDVRADVVTSRAFAELADFVSWTVHLLKDG
                     GYWAAMKGVYPQGEIDHLPQDVCVEKVQRLDVPGLDAERHIVILRKR"
     gene            complement(22077..22549)
                     /locus_tag="ACFOV4_000312"
                     /pseudo
     CDS             complement(22077..22549)
                     /locus_tag="ACFOV4_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713215.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22656..22731
                     /locus_tag="ACFOV4_000313"
     tRNA            22656..22731
                     /locus_tag="ACFOV4_000313"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22689..22691,aa:Thr,seq:cgt)
     gene            22805..23932
                     /locus_tag="ACFOV4_000314"
     CDS             22805..23932
                     /locus_tag="ACFOV4_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFC7618402.1"
                     /translation="MNTSQRNRLVSRWLNSYERYRHRRLIHAVRLGGAVLFATALARL
                     LHLQHGEWIGMTVFVVLGMLQFQGAIYSKAVERMLGTVIGLGAGLGVLWLNQHYFHGN
                     LLFYLTVGTASALAGWAAVGKNGYVPMLAGLTMCMLIGDNGSEWFDSGLMRAMNVLIG
                     AAIAIAAAKLLPLKSTLMWRFMLADNLTDCSKMIAEISNGRRMTRERLEQNMVKMRQI
                     NARMVKSRSHLAATSGESRISPAMMEAMQHAHRKIVNTTELLLTTAAKLQSPKLNGSE
                     IRLLDRHFTLLQTDLQQTVALINGRHARRIRIDTAINPELEALAEHLHYQWQGFLWLS
                     TNMRQEISALVILLQRTRRKWLDAHERQHLRQSLLETREHG"
     gene            24113..24670
                     /gene="frr"
                     /locus_tag="ACFOV4_000315"
     CDS             24113..24670
                     /gene="frr"
                     /locus_tag="ACFOV4_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFC7618403.1"
                     /translation="MINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLLDQVEVEY
                     WGSMVPVSQVANVTLLDARTIGVKPFEGNMAAKVEKAIRDSNLGLNPAAVGDLIRVPM
                     PMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDANDHIKKLLKDKEISEDEARRGEEAV
                     QKLTDKYITEADKLLTAKEEDLMAI"
     gene            24726..25472
                     /locus_tag="ACFOV4_000316"
     CDS             24726..25472
                     /locus_tag="ACFOV4_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFC7618404.1"
                     /translation="MKSSTQAVLEHTAIPKHIAVIMDGNGRWAKKRFLPRIMGHKRGL
                     DALENMVKHCAKLGVQYLTVFAFSTENWRRPEDEVSFLMGLFLQALQKQVRRLHENNM
                     RLKILGSRERFSRQILKGIEEAEALTANNTGLTLSIAADYGGRWDILQAANKLIAEGV
                     SEITEDTLAKHLMLGDAPEPDLFIRTGGETRISNFLLWQMAYAELYFTDILWPDFDGK
                     ALDDAVASFQKRERRFGRTSEQLPIEQQRN"
     gene            25475..26272
                     /locus_tag="ACFOV4_000317"
     CDS             25475..26272
                     /locus_tag="ACFOV4_000317"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFC7618405.1"
                     /translation="MLKQRVITAMWLLPLMLGMLFYAPQWLWAAFCGLIALIALWEYA
                     RMGGLCKIKTNHYLAATLVFGVVAYAGGWMLPNLVWYVVLAFWLAVMPLWLRFKWRLN
                     GGWQVYAVGWLLVMPFWFALVSLRPHPDDALPLLAVMGLVWVADVCAYFSGKAFGKHK
                     IAPAISPGKSWEGAIGGAVCVAVYMTAVRSAGWLAFDTGWFDTVLIGLVLTVVSVCGD
                     LLESWLKRAAGIKDSSNLLPGHGGVFDRTDSLIAVISVYAAMMSVLN"
     gene            26277..27512
                     /gene="ispC"
                     /locus_tag="ACFOV4_000318"
     CDS             26277..27512
                     /gene="ispC"
                     /locus_tag="ACFOV4_000318"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HFC7618406.1"
                     /translation="MPSENASDGIRYKVIPIMTPQVLTILGSTGSIGESTLDVVSLHP
                     EKFRVFALAGHKQVEKLAVQCRTFRPEYAVVADAEHAARLEALLKGDGTATQVLHGAQ
                     ALVDVASADEVSGVMCAIVGAVGLPSALAAAQKGKTIYLANKETLVVSGALFMETARA
                     NGAAVLPVDSEHNAVFQVLPRDYAGRLNEHGIASIILTASGGPFLTADLNTFDSITPD
                     QAVKHPNWRMGRKISVDSATMMNKGLELIEAHWLFNCPPDKLEVVIHPQSVIHSMVRY
                     RDGSVLAQLGNPDMRTPIAYCLGLPERIDSGVGDLDFDALSALTFQKPDFDRFPCLKL
                     AYEAMNAGGVAPCILNAANEAAVAAFLDGQIKFTDIAKTVAHCLSQDFSDGIGDIGGL
                     LAQDARTRAQARAFIGTLR"
     gene            27547..28887
                     /gene="rseP"
                     /locus_tag="ACFOV4_000319"
     CDS             27547..28887
                     /gene="rseP"
                     /locus_tag="ACFOV4_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFC7618407.1"
                     /translation="MHTLLAFIFAILILVSLHEFGHYIVARLCGVKVVRFSVGFGKPF
                     FTRKRGDTEWCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKRIAIVAAGPLT
                     NLALAVLLYGLSFSFGVTELRPYVGTVEPDTIAARAGFQSGDKIQSVNGTPVADWGSA
                     QTEIVLNLEAGKVAVGVQTASGAQTVRTIDAAGTPEAGKIAKNQGYIGLMPFKITTVA
                     GGVEKGSPAEKAGLKPGDRLTAADGKPIASWQEWANLTRQSPGKKITLTYERAGQTHT
                     ADIRPDTVEQSDHTLIGRVGLRPQPDRAWDAQIRRNYRPSVVRAFGMGWEKTVSHSWT
                     TLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQSYLEFLALVSISLGVLNLLPV
                     PVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAVAFFNDVTRLLG"
     gene            28944..31337
                     /gene="bamA"
                     /locus_tag="ACFOV4_000320"
     CDS             28944..31337
                     /gene="bamA"
                     /locus_tag="ACFOV4_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0071709 - membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HFC7618408.1"
                     /translation="MKLKQIASALMVLGISPLALADFTIQDIRVEGLQRTEPSTVFNY
                     LPVKVGDTYNDTHGSAIIKSLYATGFFDDVRVETADGQLLLTVIERPTIGSLNITGAK
                     MLQNDAIKKNLESFGLAQSQYFNQATLNQAVAGLKEEYLGRGKLNIQITPKVTKLARN
                     RVDIDITIDEGKSAKITDIEFEGNQVYSDRKLMRQMSLTEGGIWTWLTRSNQFNEQKF
                     AQDMEKVTDFYQNNGYFDFRILDTDIQTNEDKTKQTIKITVHEGGRFRWGKVSIEGDT
                     NEVPKAELEKLLTMKPGKWYERQQMTAVLGEIQNRMGSAGYAYSEISVQPLPNAETKT
                     VDFVLHIEPGRKIYVNEIHITGNNKTRDEVVRRELRQMESAPYDTSKLQRSKERVELL
                     GYFDNVQFDAVPLAGTPDKVDLNMSLTERSTGSLDLSAGWVQDTGLVMSAGVSQDNLF
                     GTGKSAALRASRSKTTLNGSLSFTDPYFTADGVSLGYDVYGKAFDPRKASTSIKQYKT
                     TTAGAGIRMSVPVTEYDRVNFGLVAEHLTVNTYNKAPKHYADFIKQYGKTDGTDGSFK
                     GWLYKGTVGWGRNKTDSALWPTRGYLTGVNAEIALPGSKLQYYSATHNQTWFFPLSKT
                     FTLMLGGEIGYANGYGKTKEIPFFENFYGGGLGSVRGYESGTLGPKVYDEYGEKISYG
                     GNKKANVSAELLFPMPGAKDARTVRLSLFADAGSVWDGKTYDDNSSSATGGRVQNIYG
                     AGNTHKSTFTNELRYSAGGAVTWLSPLGPMKFSYAYPLKKKPEDEIQRFQFQLGTTF"
     gene            31403..31903
                     /locus_tag="ACFOV4_000321"
     CDS             31403..31903
                     /locus_tag="ACFOV4_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH family outer membrane protein"
                     /protein_id="HFC7618409.1"
                     /translation="MTRLTRAFAAALIGLCCTAGAHADTFQKIGFINTERIYLESKQA
                     RKIQKTLDSEFSARQDELQKLQREGLDLERQLAEGKLRNAKKVQAEEKWRGLVAAFRK
                     KQAQFEEDYNLRRNEEFASLQQNANRVIVKIAKQEGYDVILQNVIYVNTQYDVTDSVI
                     KEMNAR"
     gene            31936..32982
                     /gene="lpxD"
                     /locus_tag="ACFOV4_000322"
     CDS             31936..32982
                     /gene="lpxD"
                     /locus_tag="ACFOV4_000322"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HFC7618410.1"
                     /translation="MIPATYTLSQITARLGGEWRGEDISVTAVRPLADAQAEHISFLA
                     NPKYKAEVHDSSAGAVIVSAKAADGFEGRNLIVADDPYLYFAKVARLFSPVVKARGGI
                     HPTAVVEPGATVPASCEIGANAYIGANTVLGEGCRILANAVVQHDCRLGDEVVLHPNA
                     VVYYGCTLGRRVEIHSGAVIGADGFGLAFAGDSWFKIPQTGAVTLGDDVEIGSNTNID
                     RGAMSDTTVGNGTKIDNQVQIGHNCKIGSHTVIAAKTGISGSVTIGSYCIIGGGVGTV
                     GHIEIADKTTIGGGTSVTHSITESGKHLAGIFPMSTHKEWARNAVYIHRLSEMNKRLK
                     TLEQQLSDAGQDSK"
     gene            33016..33465
                     /gene="fabZ"
                     /locus_tag="ACFOV4_000323"
     CDS             33016..33465
                     /gene="fabZ"
                     /locus_tag="ACFOV4_000323"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFC7618411.1"
                     /translation="MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVT
                     INEPQFQGHFPDLPVMPGVLIIEAMAQACGTLAILSEGGRKENEFFFFAGIDEARFKR
                     QVIPGDQLVFEVELLTSRRGIGKFNAVAKVDGQVAVEAIIMCAKRVV"
     gene            33672..34352
                     /locus_tag="ACFOV4_000324"
     CDS             33672..34352
                     /locus_tag="ACFOV4_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HFC7618412.1"
                     /translation="MERYKNAVGEDKAAELYLLNLSLSRELFHVVSIFEIVLRNKIDI
                     CLQQAFKDRNWLYNSIQPQTNPALKYQGCFLRNGTKESAELIKVALSKIQNNSGGKFD
                     HNQLVAGLGFGFWRYLFAGGKDAQFDVTGKVLMKVFPKKPKSTPSVQYNQKWIFRELS
                     NINKFRNRLAHHEPICFKGAIKDTNYARNIHQSIFELLNYMDVDTASVFSHFSDQVIA
                     VCDEIDKL"
     gene            34395..35171
                     /gene="lpxA"
                     /locus_tag="ACFOV4_000325"
     CDS             34395..35171
                     /gene="lpxA"
                     /locus_tag="ACFOV4_000325"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008780 -
                     acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HFC7618413.1"
                     /translation="MTLIHPTAVIDPKAELDSGVKVGAYTVIGPNVQIGANTEIGPHA
                     VINGHTSIGENNRIFQFASLGEIPQDKKYRDEPTKLIIGNGNTIREFTTFNLGTVTGI
                     GETRIGDDNWIMAYCHLAHDCVVGNHTIFANNASLAGHVTVGDYVVLGGYTLVFQFCR
                     IGDYAMTAFAAGVHKDVPPYFMASGYRAEPAGLNSEGMRRNGFTAEQISAVKNVYKTL
                     YHRGIPFEEAKADILRRAETQAELAVFRDFFAQSTRGIIR"
     gene            35528..36919
                     /locus_tag="ACFOV4_000326"
     CDS             35528..36919
                     /locus_tag="ACFOV4_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFC7618414.1"
                     /translation="MQLFLDNLKAFFETVSGWVWGSVMLMLLVGTGIVLTVLLKGLQF
                     TMLGYALKQAFVPSKKYEGGEGHEGDISHFAALMTALSATIGTGNIAGVATAVVTGGP
                     GAVFWMWITAIFGMATKYGEGVLAVKYRVNNSKGEMSGGPMYYIEKGLGKNWKWMAVA
                     FALFGTFASFGIGSSVQSNSVAQAVQTSFGIEPAYTGITLTVLTAVVVLGGIKGIAKA
                     ASFIVPAMAVFYVLGGLSIIAINSDALMPAVKLIFSDAFSAQAVAGGAIGTVIRYGVA
                     RGVFSNEAGMGSAPIAAAAAKTDHPVRQALVSMTGTFLDTIVVCSITGIVLVMGLLGA
                     GGEFVKPEVSGAALTTVTFQKMLPGIGGWIVTIGLIFFAYSTILGWCYYGEKCAVYVF
                     GEKFAGLYRVGYVSSVMLGTVLSLDLVWLASDTFNGLMALPNLIALLLMAKVIVNETR
                     DFKQKITNGELPH"
     gene            36998..38254
                     /locus_tag="ACFOV4_000327"
     CDS             36998..38254
                     /locus_tag="ACFOV4_000327"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008718 - D-amino-acid dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0055130 - D-alanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HFC7618415.1"
                     /translation="MKVLVLGAGVAGVSSAWYLAEAGHEVTVIDRAEGVAMETSFANA
                     GQLSYGYTTPWAAPGIPTKALKWLFKSHPPLLFRPDGSLYQIEWLWQMLQNCTAAHYQ
                     TNKERMVRISEYSREMFRRFEAQTGMNFEERKKGTLQIFRQAKEVEAAEQDIAVLERY
                     GVPYRRLKPEECAEFEPALARVTAKIAGGLHLPADATGDCHLFTENLYKLCQEKGVQF
                     HFNQTISRIDHNGLRIKAVETKTGRFEADAVVCALGCFSRTVLAQLDLDLPIYPVKGY
                     SLTLPVTNSDGAPVSTVLDESYKVAITRFDNRIRVGGMAELSGYEIKLPEKRRETLAL
                     VVNDLFPEGGDLSQASFWSGLRPMTPDSTPLIGRTHFDNLFLNTGHGTLGWTMSLGSA
                     KLTADIVSGKDTEIRSDDLSLSLYQA"
     gene            38435..39244
                     /gene="zupT"
                     /locus_tag="ACFOV4_000328"
     CDS             38435..39244
                     /gene="zupT"
                     /locus_tag="ACFOV4_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HFC7618416.1"
                     /translation="MPDFSMSNLAVAFSITLAAGLFTVLGSGLVMFSKTPNPRVLSFG
                     LAFAGGAMVYVSLTEIFSKSSEAFAEIYDKDHAFAAATMAFLAGMGGIALIDRLVPNP
                     HETLDAQDPSFQESKRRHIARVGMMAAFAITAHNFPEGLATFFATLENPAVGMPLALA
                     IAIHNIPEGISIAAPVYFATRSRKKTVWACLLSGLAEPLGAALGYLVLQPFLSPAVFG
                     SVFGVIAGVMVFLALDELLPAAKRYSDGHETVYGLTTGMAVIAVSLVLFHF"
     gene            39341..42178
                     /locus_tag="ACFOV4_000329"
     CDS             39341..42178
                     /locus_tag="ACFOV4_000329"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFC7618417.1"
                     /translation="MLDKYSPAEIESKHYQNWESQGYFQPDMDLTKPSFSIQLPPPNV
                     TGTLHMGHTFNQTIMDGLTRYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRH
                     DLGREKFLEKVWEWKEVSGGTITQQMRRVGCSADWTREYFTMDDVRAETVTEVFVRLY
                     EQGLIYRGKRLVNWDPVLGTAVSDLEVESVEEQGSMWHIRYPLADNPAEAVIVATTRP
                     ETLLGDVAVAVNPEDERYTHLIGKELILPLTGRTIPVIADEYVEKDFGTGCVKITPAH
                     DFNDYEVGKRHDTRLVNVFDLEAKVLANAEVFNFKGEAQPSFALPEKYAGLDRFAARK
                     QMVADLQEQGFLVEIKAHTLMTPKGDRTGSVIEPMLTSQWFVAMSATPNGGEPDSEFK
                     GLSLADKAKKAVDSGAVRFIPENWVNTYNQWMNNIQDWCISRQLWWGHQIPAWYDNEG
                     NVYVARNQEEAEKQAGKTGLTREEDVLDTWFSSALVPFSTLGWPSETDELKAFLPSNV
                     LVTGYEIIFFWVARMIMMTTHFTGKVPFKDVYIHGIVRDHEGKKMSKSEGNVIDPVDL
                     IDGIDLEKLLVKRTTGLRKPETAPKVEEATKKLFPEGIPSMGADALRFTMASYASLGR
                     SVNFDFKRAEGYRNFCNKIWNATNFVLMNTENQDCGYGATATEPRGYSFPDMWIVGRL
                     NQTIEQVTQAYETYRFDLAAETLYSFVWNDYCDWYLELAKVQLQTGCASRQRATRHTL
                     LRVLEAALRLLHPIIPFITEELWQTVAPMCDAKTADSIMLARFPEADGGEIVQTAFGQ
                     MTVLQDLIGAVRNLRGEMGIQPNVKAPLFVESADDLADYLKYLPMMTRLTEAQQVAAL
                     PESEDAPVAVCNGARLMLKVEIDKAAETARLSKEAEKLQKALDKLNAKLSKPGYTEKA
                     PAHLVEKDKADLAELEDKMAKVQTQLSKLKD"
     gene            42320..42511
                     /locus_tag="ACFOV4_000330"
     CDS             42320..42511
                     /locus_tag="ACFOV4_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618418.1"
                     /translation="MLIHYTWHCIGTDENIHSDAKVEYLQDGSFRGDAILKIDDDGNI
                     LAYRVVGSGKWRFENNACA"
     gene            complement(42508..43428)
                     /gene="oxyR"
                     /locus_tag="ACFOV4_000331"
     CDS             complement(42508..43428)
                     /gene="oxyR"
                     /locus_tag="ACFOV4_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator OxyR"
                     /protein_id="HFC7618419.1"
                     /translation="MTLTELRYIVAVAQERHFGRAARRCFVSQPTLSIAIKKLEEELA
                     VSLFDRSSNDIITTEAGERIVAQARKVLEEAELIRHLANEEQNELEGAFKLGLIFTVA
                     PYLLPKLIVSLRRTAPKMPLMLEENYTHTLTESLKRGDVDAIIVAEPFQEPGIVTEPL
                     YDEPFFVIVPKGHSFEELDAVSPRMLGEEQVLLLTEGNCMRDQVLSSCSELAAKQRIQ
                     GLTNTLQGSSINTIRHMVASGLAISVLPATALTENDHMLFSIIPFEGTPPSRRVVLAY
                     RRNFVRPKALSAMKAAIMQSQLHGVSFIRD"
     gene            complement(43432..43695)
                     /gene="minE"
                     /locus_tag="ACFOV4_000332"
     CDS             complement(43432..43695)
                     /gene="minE"
                     /locus_tag="ACFOV4_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HFC7618420.1"
                     /translation="MSLIELLFGRKQKTATVARDRLQIIIAQERAQEGQAPDYLPTLR
                     KELMEVLSKYVDVSLDNIRISQEKQDGMDVLELNITLPEQKKV"
     gene            complement(43699..44514)
                     /gene="minD"
                     /locus_tag="ACFOV4_000333"
     CDS             complement(43699..44514)
                     /gene="minD"
                     /locus_tag="ACFOV4_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HFC7618421.1"
                     /translation="MAKIIVVTSGKGGVGKTTTSASIATGLALRGYKTAVIDFDVGLR
                     NLDLIMGCERRVVYDLINVIQGEATLNQALIKDKNCENLFILPASQTRDKDALTREGV
                     EKVMQELSGKKMGFEYIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILG
                     ILQSKSHKAEQGGSVKEHLLITRYSPERVAKGEMLSVQDICDILHIPLLGVIPESQNV
                     LQASNSGEPVIHQDSVAASEAYKDVIARLLGENREMRFLEAEKKSFFKRLFGG"
     gene            complement(44543..45256)
                     /gene="minC"
                     /locus_tag="ACFOV4_000334"
     CDS             complement(44543..45256)
                     /gene="minC"
                     /locus_tag="ACFOV4_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004857 - enzyme inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA];
                     GO_process: GO:1901891 - regulation of cell septum
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HFC7618422.1"
                     /translation="MMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQE
                     SGVVPFVLDVQEFDYPESLDLAALVSLFSRHGMQILGLKHSDERWAAAAMKYHLLFCL
                     SHSENVKELGQVEVQKTEDGQKARKTVLITSPVRTGQQVYAEDGDLIVTGAVSQGAEL
                     IADGNIHIYAPMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPDHLHKQ
                     PVQILLQDNRLVISAIGSE"
     gene            complement(45403..45771)
                     /gene="rplQ"
                     /locus_tag="ACFOV4_000335"
     CDS             complement(45403..45771)
                     /gene="rplQ"
                     /locus_tag="ACFOV4_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFC7618423.1"
                     /translation="MRHRNGNRKLNRTSSHRAAMLRNMANSLLTHETIVTTLPKAKEL
                     RRVVEPLITLGKKPSLANRRLAFDRTRDRDVVVKLFGDLGPRFTARNGGYVRVLKYGF
                     RKGDNAPLALVELVDKPAAE"
     gene            complement(45795..46781)
                     /gene="rpoA"
                     /locus_tag="ACFOV4_000336"
     CDS             complement(45795..46781)
                     /gene="rpoA"
                     /locus_tag="ACFOV4_000336"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFC7618424.1"
                     /translation="MQNSTTEFLKPRQIDVNTFSATRAKVSMQPFERGFGHTLGNALR
                     RILLSSMNGFAPTEVAIAGVLHEYSTVDGIQEDVVDILLNIKGIVFKLHGRSQVQLVL
                     KKSGSGVVSAGDIELPHDVEILNPGHVICHLADNGQIEMEIKVEQGRGYQSVSGRQVV
                     RDENRQIGAIQLDASFSPISRVSFEVEPARVEQRTDLDKLVLDIETDGSIDPEEAVRS
                     AARILIDQMSIFADLQGTPVEEVEEKAPPIDPVLLRPVDDLELTVRSANCLKAEDIYY
                     IGDLIQRTETELLKTPNLGRKSLNEIKEVLASKGLTLGSKLEAWPPVGLEKP"
     gene            complement(46807..47427)
                     /gene="rpsD"
                     /locus_tag="ACFOV4_000337"
     CDS             complement(46807..47427)
                     /gene="rpsD"
                     /locus_tag="ACFOV4_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFC7618425.1"
                     /translation="MARYIGPKCKLARREGTDLFLKSARRSLDSKCKIDSAPGQHGAK
                     KPRLSDYGLQLREKQKIRRIYGVLERQFRRYFAEADRRKGSTGELLLQLLESRLDNVV
                     YRMGFGSTRAEARQLVSHKAIVVNGQVVNIPSFQVKAGDVVSVREKAKKQVRIQEALG
                     LATQIGLPGWVSVDADKLEGVFKNMPDRSELTGDINEQLVVEFYSK"
     gene            complement(47447..47842)
                     /gene="rpsK"
                     /locus_tag="ACFOV4_000338"
     CDS             complement(47447..47842)
                     /gene="rpsK"
                     /locus_tag="ACFOV4_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFC7618426.1"
                     /translation="MAKANTASRVRKKVRKTVSEGIVHVHASFNNTIITITDRQGNAL
                     SWATSGGAGFKGSRKSTPFAAQVAAEAAGKVAQEYGVKNLEVRIKGPGPGRESSVRAL
                     NALGFKITSITDVTPLPHNGCRPPKKRRI"
     gene            complement(47862..48224)
                     /gene="rpsM"
                     /locus_tag="ACFOV4_000339"
     CDS             complement(47862..48224)
                     /gene="rpsM"
                     /locus_tag="ACFOV4_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFC7618427.1"
                     /translation="MARIAGVNIPNNAHIVIGLQAIYGIGATRAKLICEAANIAPDTK
                     AKDLDETQLDALRDQVAKYEVEGDLRREVTMSIKRLMDMGCYRGFRHRRGLPCRGQRT
                     RTNARTRKGPRKAIAGKK"
     gene            complement(48290..48403)
                     /gene="rpmJ"
                     /locus_tag="ACFOV4_000340"
     CDS             complement(48290..48403)
                     /gene="rpmJ"
                     /locus_tag="ACFOV4_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006232360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFC7618428.1"
                     /translation="MRVQPSVKKICRNCKIIRRNRVVRVICTDLRHKQRQG"
     gene            complement(48424..48642)
                     /gene="infA"
                     /locus_tag="ACFOV4_000341"
     CDS             complement(48424..48642)
                     /gene="infA"
                     /locus_tag="ACFOV4_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFC7618429.1"
                     /translation="MAKEDTIQMQGEILETLPNATFKVKLENDHIVLGHISGKMRMHY
                     IRISPGDKVTVELTPYDLTRARIVFRAR"
     gene            complement(48647..49957)
                     /gene="secY"
                     /locus_tag="ACFOV4_000342"
     CDS             complement(48647..49957)
                     /gene="secY"
                     /locus_tag="ACFOV4_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFC7618430.1"
                     /translation="MANQQTSSGSSKFGDLKKRLLFLFGALIVFRIGAHIPVPGVDAV
                     ALAKLYESAGNGILGILNMFSGGSLERFSIFAIGIMPYISASIIVQLASEILPSLKAL
                     KKEGEAGRKVITKYTRYGTVLLAILQSLGVASFVFQQGIVVTSSFEFHVSTVVSLVTG
                     TMFLMWLGEQITERGIGNGISLIITAGIASGIPSGIAKLVTLTNQGSMSMLTALFIVF
                     GALLLIYLVVYFESAQRKIPIHYAKRQFNGRAGSQNTHMPFKLNMAGVIPPIFASSII
                     LFPSTLLGWFGSADTNSVLHKIAGLLQHGQLLYMALFAATVIFFCYFYTALVFSPKEM
                     AENLKKSGAFVPGIRPGEQTSRYLEKVVLRLTLFGALYITTICLIPEFLTTVLNVPFY
                     LGGTSLLILVVVTMDFSTQINSYRLTQQYDKLMTRSEMKSFSRK"
     gene            complement(49969..50403)
                     /gene="rplO"
                     /locus_tag="ACFOV4_000343"
     CDS             complement(49969..50403)
                     /gene="rplO"
                     /locus_tag="ACFOV4_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFC7618431.1"
                     /translation="MFLNTIQPAVGATHAGRRVGRGIGSGLGKTGGRGHKGQKSRSGG
                     FHKVGFEGGQMPLQRRLPKRGFKSLTASANAQLRLSELESIAVNEIDILVLKQAGLIA
                     STVSNVKVIASGEISKAVALKGIKVTKGARAAIEAVGGKIEM"
     gene            complement(50405..50590)
                     /gene="rpmD"
                     /locus_tag="ACFOV4_000344"
     CDS             complement(50405..50590)
                     /gene="rpmD"
                     /locus_tag="ACFOV4_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFC7618432.1"
                     /translation="MAEQKKIRVTLVKSLIGTIESHRACARGLGLRRREHTVEVLDTP
                     ENRGMINKISYLLKVES"
     gene            complement(50583..51101)
                     /gene="rpsE"
                     /locus_tag="ACFOV4_000345"
     CDS             complement(50583..51101)
                     /gene="rpsE"
                     /locus_tag="ACFOV4_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFC7618433.1"
                     /translation="MAKHEIEERGDGLIEKMVAVNRVTKVVKGGRIMAFSALTVVGDG
                     DGRIGMGKGKSKEVPVAVQKAMDQARRSMIKVPLKNGTIHHEVIGRHGATKVFMQPAK
                     EGSGVKAGGPMRLVFDAMGIHNISAKVHGSTNPYNIVRATLDGLSKLHTPADIAAKRG
                     LTVEDILGVNHG"
     gene            complement(51120..51473)
                     /gene="rplR"
                     /locus_tag="ACFOV4_000346"
     CDS             complement(51120..51473)
                     /gene="rplR"
                     /locus_tag="ACFOV4_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFC7618434.1"
                     /translation="MDKHTTRLRRARKTRARIADLKMVRLCVFRSNNHIYAQVISAEG
                     DKVLAQASTLEAEVRGSLKSGSNVEAAAIVGKRIAEKAKAAGVEKVAFDRSGFQYHGR
                     VKALAEAARENGLSF"
     gene            complement(51487..52020)
                     /gene="rplF"
                     /locus_tag="ACFOV4_000347"
     CDS             complement(51487..52020)
                     /gene="rplF"
                     /locus_tag="ACFOV4_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFC7618435.1"
                     /translation="MSRVAKNPVTVPAGVEVKFGTEALVIKGKNGELSFPLHSDVAIE
                     FNDGKLAFVANNSSKQANAMSGTARALVSNMVKGVSEGFEKRLQLIGVGYRAQAQGKI
                     LNLSLGFSHPIVYEMPEGVSVQTPSQTEIVLTGSDKQVVGQVAAEIRAFRAPEPYKGK
                     GVRYVGEVVVMKEAKKK"
     gene            complement(52034..52426)
                     /gene="rpsH"
                     /locus_tag="ACFOV4_000348"
     CDS             complement(52034..52426)
                     /gene="rpsH"
                     /locus_tag="ACFOV4_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFC7618436.1"
                     /translation="MSMHDPISDMLTRIRNAQRANKAAVAMPSSKLKCAIAKVLKEEG
                     YIEDFAVSSDVKSILEIQLKYYADRPVIEQIKRVSRPGLRIYKASSEIPSVMNGLGIA
                     IVSTSKGVMTDRKARSQGVGGELLCIVA"
     gene            complement(52442..52747)
                     /gene="rpsN"
                     /locus_tag="ACFOV4_000349"
     CDS             complement(52442..52747)
                     /gene="rpsN"
                     /locus_tag="ACFOV4_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFC7618437.1"
                     /translation="MAKKALINRNLKRQALAKKYAAKRAAIKAVINDSNATEEERFEA
                     RLRFQSIPRNAAPVRQRRRCALTGRPRGTFRKFGLGRIKIREIAMRGEIPGVVKASW"
     gene            complement(52750..53289)
                     /gene="rplE"
                     /locus_tag="ACFOV4_000350"
     CDS             complement(52750..53289)
                     /gene="rplE"
                     /locus_tag="ACFOV4_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008955648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFC7618438.1"
                     /translation="MARLREFYKETVVPELVKQFGYKSVMEVPRIEKITLNMGVGEAV
                     ADKKVMEHAVSDLEKIAGQKPVVTVARKSIAGFKIRDNYPVGCKVTLRRDQMFEFLDR
                     LITIALPRVRDFRGVSGKSFDGRGNYNMGVREQIIFPEIEYDKIDALRGLNITITTTA
                     KTDEEAKALLSLFKFPFKG"
     gene            complement(53299..53622)
                     /gene="rplX"
                     /locus_tag="ACFOV4_000351"
     CDS             complement(53299..53622)
                     /gene="rplX"
                     /locus_tag="ACFOV4_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFC7618439.1"
                     /translation="MNKIIKGDRVVVIAGKDKGKQGQVVRVLGDKVVVEGVNVVKRHQ
                     KPNPMRGIEGGIITKEMPLDISNIAILNPETNKADRVGIKLIENEGKVKRVRFFKSNG
                     SIIGA"
     gene            complement(53634..54002)
                     /gene="rplN"
                     /locus_tag="ACFOV4_000352"
     CDS             complement(53634..54002)
                     /gene="rplN"
                     /locus_tag="ACFOV4_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012728338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFC7618440.1"
                     /translation="MIQMQTILDVADNSGARRVMCIKVLGGSKRRYASVGDIIKVAVK
                     DAAPRGRVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLNNKLEPLGTRIFGPV
                     TRELRTERFMKIVSLAPEVL"
     gene            complement(54224..54487)
                     /gene="rpsQ"
                     /locus_tag="ACFOV4_000353"
     CDS             complement(54224..54487)
                     /gene="rpsQ"
                     /locus_tag="ACFOV4_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFC7618441.1"
                     /translation="MSETKNVRTLQGKVVSDKMDKTVTVLVERKVKHPLYGKIIRLST
                     KIHAHDENNQYGIGDVVVISESRPLSKTKSWVVSELVEKARSI"
     gene            complement(54487..54678)
                     /gene="rpmC"
                     /locus_tag="ACFOV4_000354"
     CDS             complement(54487..54678)
                     /gene="rpmC"
                     /locus_tag="ACFOV4_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009175233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFC7618442.1"
                     /translation="MKANELKDKSVEQLNADLLDLLKAQFGLRMQNATGQLGKPSELK
                     RVRRDIARIKTVLTEKGAK"
     gene            complement(54678..55094)
                     /gene="rplP"
                     /locus_tag="ACFOV4_000355"
     CDS             complement(54678..55094)
                     /gene="rplP"
                     /locus_tag="ACFOV4_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008955643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFC7618443.1"
                     /translation="MLQPTRLKYRKQQKGRNTGIATRGNKVSFGEFGLKAVGRGRLTA
                     RQIEAARRAMTRHIKRGGRIWIRVFPDKPITEKPIQVRMGGGKGNVEYYIAEIKPGKV
                     LYEMDGVPEELAREAFELAAAKLPIPTTFVVRQVGQ"
     gene            complement(55078..55770)
                     /gene="rpsC"
                     /locus_tag="ACFOV4_000356"
     CDS             complement(55078..55770)
                     /gene="rpsC"
                     /locus_tag="ACFOV4_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFC7618444.1"
                     /translation="MGQKINPTGFRLAVTKDWASKWFAKSTDFSTVLKQDIDVRNYLR
                     QKLANASVGRVVIERPAKSARITIHSARPGVVIGKKGEDIEVLKRDLQVLMGVPVHVN
                     IEEIRRPELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRSGAKGIKIMTSGRLNGA
                     DIARSEWYREGRVPLHTLRANVDYATSEAHTTYGVLGLKVWVYTEGNIKSSKPEHESK
                     QRKAGRRNAAAN"
     gene            complement(55780..56109)
                     /gene="rplV"
                     /locus_tag="ACFOV4_000357"
     CDS             complement(55780..56109)
                     /gene="rplV"
                     /locus_tag="ACFOV4_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003795898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFC7618445.1"
                     /translation="MRVNAQHKNARISAQKARLVADLIRGKDVAQALNILAFSPKKGA
                     ELIKKVLESAIANAEHNNGADIDELKVVTIFVDKGPSLKRFQARAKGRGNRIEKQTCH
                     INVTVGN"
     gene            complement(56118..56396)
                     /gene="rpsS"
                     /locus_tag="ACFOV4_000358"
     CDS             complement(56118..56396)
                     /gene="rpsS"
                     /locus_tag="ACFOV4_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFC7618446.1"
                     /translation="MARSLKKGPYVDLHLLKKVDAARASNDKRPIKTWSRRSTILPDF
                     IGLTIAVHNGRTHVPVFISDNMVGHKLGEFSLTRTFKGHLADKKAKKK"
     gene            complement(56403..57236)
                     /gene="rplB"
                     /locus_tag="ACFOV4_000359"
     CDS             complement(56403..57236)
                     /gene="rplB"
                     /locus_tag="ACFOV4_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFC7618447.1"
                     /translation="MAIVKMKPTSAGRRGMVRVVTEGLHKGAPYAPLLEKKNSTAGRN
                     SNGHITTRHKGGGHKHHYRVVDFKRNKDGIPAKVERIEYDPNRTAFIALLCYADGERR
                     YIIAPRGIQVGAVLVSGAEAAIKVGNTLPIRNIPVGTTIHCIEMKPGKGAQIARSAGA
                     SAVLLAKEGAYAQVRLRSGEVRKINVNCRATIGEVGNEEQSLKKIGKAGANRWRGIRP
                     TVRGVVMNPVDHPHGGGEGRTGEAREPVSPWGTPAKGYRTRNNKRTDNMIVRRRYSNK
                     G"
     gene            complement(57242..57556)
                     /gene="rplW"
                     /locus_tag="ACFOV4_000360"
     CDS             complement(57242..57556)
                     /gene="rplW"
                     /locus_tag="ACFOV4_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFC7618448.1"
                     /translation="MNQQRLTQVILAPIVSEKSNVLAEKRNQMTFKVLANATKPEIKA
                     AVELLFGVQVASVTTVTTKGKTKRFGRTLGRRSDVKKAYVSLAAGQELDLEAAAAAAD
                     KE"
     gene            complement(57553..58173)
                     /gene="rplD"
                     /locus_tag="ACFOV4_000361"
     CDS             complement(57553..58173)
                     /gene="rplD"
                     /locus_tag="ACFOV4_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFC7618449.1"
                     /translation="MELKVIDAKGQVSGSLSVSDALFAREYNEALVHQLVNAYLANAR
                     SGNRAQKTRAEVKHSTKKPWRQKGTGRARSGMTSSPLWRKGGRAFPNKPDENFTQKVN
                     RKMYRAGMATILSQLTRDERLFAIEALTAETPKTKVFAEQVKNLGLEQVLFVTKQLDE
                     NVYLASRNLPNVLVLEAQQVDPYSLLRYKKVIITKDAVAQLEEQWV"
     gene            complement(58173..58817)
                     /gene="rplC"
                     /locus_tag="ACFOV4_000362"
     CDS             complement(58173..58817)
                     /gene="rplC"
                     /locus_tag="ACFOV4_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFC7618450.1"
                     /translation="MTLGLVGRKVGMTRVFDEQGVSVPVTVLDMSANRVTQVKSKDTD
                     GYTAVQVTFGQKKANRVNKAEAGHFAKAGVEAGRGLIEFALTEEKLAELKAGDEITVS
                     MFEVGQLVDVTGTSKGKGFSGTIKRHNFGAQRTSHGNSRSHRVPGSIGMAQDPGRVFP
                     GKRMAGQYGNTKATVQKLEVVRVDAERQLLLVKGAVPGAVNSDVVVRPSVKVGA"
BASE COUNT        15274 a        17048 c        13704 g        13126 t
ORIGIN      
        1 agacgctcta ccaactgagc taatcaccct tgcgatttgc gaaagcgtta ttaaaccaaa
       61 taaccggaaa tggcgcaagc cttatttcgg catttcattt atattccctg caaactccag
      121 ttttcaaaag agataatttc ttcttttttg cctgcgacca ccaacacgtc accgcctttc
      181 aatgtaaacg aggcatccgg gttttcaatc cggccggtgc ggcggcggac gaacaagagt
      241 ttgatgccgt aagccgccat cggaagcgtg ccgactgttt tgccgacggc gtatgcttct
      301 gcagccaaag gaaaggcgtg acggacggtt tcgccgtttt cgccgaatcc tgcctcatca
      361 tcactaccga caaacagtcc ctccaacgcg gcataacggc tgtggcggat atttgccatc
      421 gtctgataga cgtgccgata cgacgcgccg ttgcctaaca tcgcatagcc tgccagcacg
      481 agtccggttt ctttggtgtc cgacacggct tcttccgcac ctatatcggt aaacgttttc
      541 acataatcgt cgttggtggc gcgcacatat acgggcatat tgggatacat ggacagcaca
      601 ttgtctaaaa cgtgttgcgt ttcgtgcata ttgttgagcg tcagcaccac cattttcgcc
      661 cgtcccagac cggcggcttc caatacttcc ctgcgtttcg catcgccgaa cgacaccggt
      721 tcgcccgcac ttctggcaac ctgcacccgc gcaatgtcca agtcgagcgc gaaatacgga
      781 atatcctctt gggcaaggac gcgtccgacc gtctgcccgc ccctgccgaa gccgacaatc
      841 agcacatggt cggacttgct catggtttct accagcatac tgtgcagatc gagcgacttc
      901 atgtcccagc ttgacttgac caaacgcccg accagcgcat cgctgccgcc caagaggaag
      961 ggcgcgataa tcatcgacag cagaaccgcc gctgtcgccg cctgttccca ttctggcgaa
     1021 accatatcaa gctgcccggc aatggccagc atcacgaagc cgaactcgcc gccctgcgcg
     1081 agatacaaag ccgttttgag gctgtcgccg accgaatgtt tcattttgaa ggcaatggca
     1141 aacacaacca gtgccttcaa caccagcagc attgccaaca gcatcaatac ctgccgccaa
     1201 ccgccgatca atgcctgaat gtccagcttc atgccgaccg tgataaagaa aaagccgagc
     1261 aaaatatcgc ggaacgggcg gatgtcgtct tcgacttgga aacggtattc cgtttccgaa
     1321 agcagcatgc cggcaacgaa tgcgcccaac gccatagaca aaccttccag ctcagtcaga
     1381 taagccacac ccaaggttac cagcagcaca ttgatcataa agagttcgga cgatttgcgt
     1441 tttgccacca tcctgaacca tcgcgacata attttgctgc cgacgaaaaa cagcagcccc
     1501 agcgtcagca gcatttttgc aaacgccaaa cccaaggccg cccaaatatt tccgtcccct
     1561 ccgcccgcca gcgcgggaat cagaatcatc agcggcacga cggcgatgtc ctgcatcagc
     1621 agcacgccca tcgccatctg accgtgcggc tgccccaatt ccgtcttttc cgacaaaatc
     1681 cggctcacaa tcgccgtgga cgacatcgcc aacgcgcccg acacggcaaa cgcccaattg
     1741 aacgggacgc ccgtcagcat cagtatgccc attaccgaca gcatcgtaac gccgacctgc
     1801 aaaccgccca gcccgaacac cagccgcctc attgccctca gcttgggcag cgaaaactcc
     1861 aagcctatac tgaacatcag gaacacaatc ccgatttcgc ccaaataatc cgttgcatga
     1921 cttttcggaa tcaggctgag cataccgggc cccgccaaaa agcccaccag caggtagccc
     1981 agcatggagg gaatgttgaa cttgcggcac aggatcaccg taatgaccga caccagcaaa
     2041 acaaccacaa taggggcaag cgaaaattcg ttcataggtc gtccgaacag gaaaatacag
     2101 aaaaatgccg tctgaaacgg catacgccgc cgtattataa caaaacaccg cgcaccatcc
     2161 gaaacgggcg cggcatacaa ttctgctaaa atacgccctt tcgattttga gccgcacacc
     2221 gacatgaccg ccacagccgc cgccatagac cgcctgcttc cccaaaccca atgccgcgaa
     2281 tgcggctacg acggctgcct gccctacgca caggcagtcg caacaggcga agcgtacaac
     2341 ctctgcgccc cgggcggaga agccgtcatt cgggacattt ccgccctgct cggcaaaccc
     2401 cttgtcgcac ctgccaaaac ccaagccaaa gcactcgccc agatagacga aaccgcctgt
     2461 atcggctgca ccgcctgcat ccgcgcctgc cctgccgatg ccattatggg tgcgggcaaa
     2521 cttatgcaca ccgtcatcgc cgacgaatgc accggctgcg gactctgcgt cgccccctgc
     2581 cccgtcgact gcatccatat gcagcccgtt gccgacaccg tcctgccccg cgcgcgccgc
     2641 ttcagcctgt ccgccgacag ccgttttgcc gccgccgaac acgcgcgtgc gcgctacctc
     2701 aaacgcaacg aacgcaaaca gcgcgaagcc gacgaacgca aggccatgct tgccgaacgc
     2761 gaagccgccg tccgcaacgc gcgtccgcaa acacccgaca caccgaaaaa accggcgttt
     2821 aaccctgccg acctcatcgc caaagccatg gcaaaagcgc aaacccaaca agaccgcctc
     2881 gccgccgccg acaaccgcaa agactatcag gcgaaacaga tagccgaagc ccgcgaacgc
     2941 gccgagttgc gccgcgccca acgcgatatg aaatacggca gcgacagcga aaaagccgcc
     3001 gccctcgaat atctcaaaca atacaaagcc aaacaggaag ccgcacagaa taccgcctcc
     3061 tgacccttcc ttgatatgcc gtctgaagcc gcttcagacg gcattttatc aagctctccg
     3121 tccgccgcac ccgtgccgtc cgcatcttac cgcccaccct tccggccgcg ccgttttcaa
     3181 taaaatatta attacacgcc actacaaatt tgctataatc cgccccgaaa atctacccaa
     3241 cccctcgaca aaggaacaaa ccatgggcat caaagtcgcc atcaacggct acggacgcat
     3301 cggccgccag gttttgcgcg ccatctacga ctatcagatt caagaccaac tccaaatcgt
     3361 cgccgtcaac gccagcggca gccttgaaac caacgcccat ctcaccaaat tcgacaccgt
     3421 gcacggacgc tttgaagccg acgtatccca cgacggcggc aacctcatcg tcaacggcga
     3481 caaaatcccc ttcttctcga cccgcaaccc tgccgaactg ccgtggaaag aactcggtgt
     3541 cgatttggtc atggaatgca ccggcgcgtt caccagcaaa gaaaaagcca aagttcatct
     3601 ggaaagcggc gcgaaaaaag tcctcatttc cgcaccgggc ggcgacgatg tcgatgcaac
     3661 cgtcgtgtac ggcgtgaacg acagcgtcct gaccgccgac atgaccgtcg tttccaacgc
     3721 ttcctgcacc accaactgcc tctcgccggt tgccaaagtg ttgagcgaaa gcgtcggcat
     3781 cgtcaaaggc gcgatgacca ccatccacgc gctgaccaac gaccaaaccg ttaccgacgt
     3841 gcgccacaaa gacctgcgcc gcgcccgcag cggcgtggaa aacatgattc cgaccaaaac
     3901 cggcgcggca aaagccgtcg gtttggtctt gcccgaattg aaaggcaggc tcgacgggct
     3961 tgccatccgc gtgccgaccg tcaacgtatc attggtagat ttgaacttcc aagccgcgcg
     4021 cgacacgaca atcgaagaaa tcaacgcact gatgaaagcc gcctcggaag caggcgcgct
     4081 caaaggcgtt ttaggctaca acaccctgcc cttggtttcc atggacttca accacactac
     4141 cgaagccagc cacttcgacg caacgctgac caaagtcgtt gacggcaaca tgattaaagt
     4201 cttcgcatgg tatgacaacg aatggggctt cagctgccaa atgctgaaca ccgcacgccg
     4261 tatgttcgga cttgaagtgc gcccgctcaa ataagcaata aaccgtcaaa caaaatgccg
     4321 tctgaaaccc gatgttttca agttccagac ggcatttttc atttttggca gtgattttgc
     4381 ccggctgtcg tcatttctaa ttttatagtg gattaacaaa aaccagtacg gcgttgcctc
     4441 gccttgccgt actatttgta ctgtctgcgg cttcgtcgcc ttgtcctgat ttttgttaat
     4501 ccactataat ccaccatatt tgaacctgac cgaagcataa gccgccatca aagccccttg
     4561 cacgccactt cgcgccgccc gatttcctct ttcaacggca cggcgttcaa catccgcaga
     4621 cgttcggcaa aatccgcaaa cggcagcagc tccgaaccga aacggcgcat atgttccgtg
     4681 tcctgctggc agtctatcag ttccacaccc aaatccgcca aaaacggcac ggcgcaggca
     4741 aacgcgattt tcgacgcatc cggttgcaac gcaaacatcg attcgccata aaacacgctg
     4801 ccgatctgca cgccgtaaaa gccgcccgcc aacctcgttt caccgctttc atcgggataa
     4861 tggcactcga aagaatgcgc gtgtcccatt tcgtgcagct tcaaatatgc cgtctgaaac
     4921 tcgggcgcaa tccaagttcc gtcctgattc gggcgcgccg ctgccgcaca atgcgcgacc
     4981 acttccgcaa aacagccgtt gaccgcaacc cgatagctgc cgttgcgcag cgttttcgcc
     5041 agcgagcgcg gaacgtgcag acgttcggga acaatcaccg cacgcgggcc gaccgcatac
     5101 caaaaaaacc aaccgtcccg agaaaaccac ggaaacacgc cgttccgata cgcctcgagc
     5161 agccgccccg catccaaatc gccgctcacg ccgaccagcc cgtcgcaccg ggccaaagca
     5221 taggcaggat cgggaaaggc ataattgtca ggggcaagca gcggaatacg catggcagtt
     5281 ctccaaaaac acagacggca tccaaaatca tgaatgccgt ctgaacaaca aaccgtccgg
     5341 atttaacgtt tgcccttggc ctgacagtcg ctgcacacgc cgtacatata aagcgcgtga
     5401 tcgacgatgc ggtagccgtt ttcctcagcg attttgtctt gcagggcttc gatttcggga
     5461 ttgtggaatt ccgttacctc gccgcacttc acgcagacga tatggtcgtg gtggtcgccc
     5521 ttgtccaact cataaaccgc cttgcccgtt tcaaaatggt ggcgttgcag aatgcccgcc
     5581 tgctcaaact gggtcagcac gcggtaaatc gtcgccacac cgatttccac accctcttcc
     5641 aacaaaatgc ggtacacatc ttccgcactc aaatgctctt ccgcatgcgt ctcgaacaaa
     5701 tccaaaatct tcaaacgcgg gccggtaacc ttcagaccgc tgtctttcag ttgtgcaata
     5761 ttgttgaatt tttccataat attcaatacc cctgtaaaac aatagacgtt ataatacgca
     5821 atttcggcct gtttgcccac tatcgcacca tagcagtttg caatagtaaa accgcaccgg
     5881 cggccgatgc gcggacaggg cggataccgc ttaatcgtat gattatcgtt cgcttttata
     5941 aaatattcaa gcagtgttac actacccatc ccgatttgca cagaaaggca tttccgtgaa
     6001 caaaaccctc atcctcgccc tttccgccct cctcggcctt gccgcgtgca gcgtcgaacg
     6061 cgtttcactg ttcccctcgt acaaactcaa aatcatacag ggcaacgaac tcgaacctcg
     6121 cgccgtcgcc tccctccgcc ccggtatgac caaagaccaa gtcctgctcc tgctcggcag
     6181 ccccatactg cgcgacgcat tccataccga ccgctgggac tataccttca acacctcccg
     6241 caacggcatc atcaaagacc gaagcaatct gaccgtctat tttgaaaacg gcgtgctcgt
     6301 ccgcaccgaa ggcaacgccc tgcaaaatgc cgccgaagcc ctccgcgtaa aacaaaacgc
     6361 agacaaacaa taaggaacac acatgacacc gctcaaaatc gccatcgccg gcgcaaacgg
     6421 ccgtatgggg cgcgtcctcg tcgaagccgt caacaaccat cccgacaccg tcctttccgg
     6481 tgcgcttgaa cactcaggct cagaagccct cgggctggac gcaggctacg ccgtcggact
     6541 caaaaccggc atcgccattt cagacgacgt tgacgccgtt ctcgcacaaa gcgacgtact
     6601 catcgacttc acccgccccg agcccaccct caaacacctg caaaaatgcg ttgaaaaaca
     6661 agtcaacatc atcatcggca caacaggctt cgacgatgcg ggcaaagccg ctatccacac
     6721 tgccgccgaa caaacaggca tcgttttcgc cgccaacttc agcgtcggcg tcaacctcac
     6781 cttccacatc ctcgacaccg tcgcccgcgt gttaaacgaa ggctacgaca tcgaaatcat
     6841 tgaaggccac caccgccaca aagtcgatgc ccccagcggc accgcgttac gcatgggcga
     6901 agtcatcgcc ggcgcgctcg gcagagacct caaacaatgc gccgtttacg gccgcgaagg
     6961 ccacaccggt ccgcgcgatc cgtcgaccat cggctttgcc accgtccgcg caggcgacat
     7021 cgtcggcgac cacaccgccc tcttcgccac cgacggcgag cgcgtggaaa tcacccacaa
     7081 agccggcagc cgcatgacct ttgccgccgg cgccgtccgc gccgcagttt gggtaaacgg
     7141 caaaacgggt ttgtacgata tgcaggacgt actcgggctg aacaaccgtt aacccccata
     7201 caaaatgccg tctgaaaaga tattgttcag acggcatttt gccgacaggc tccgtatcgg
     7261 catatcaatg tttcaacaca cgggacgata cataaagcgt cgccctatgt gtcgtcctga
     7321 tttggaaggg attacgcccc tcccaaataa agtctgattc taccgccccg aaggacagat
     7381 gtccgagtgg cggggtttca accgaaaagg aaatacgata aagttgcttg cgcggcatga
     7441 caagttacgg ctcgtttaat taaaactctc ctgatctaaa aattctaact ctatttcccg
     7501 gcaaactata tctatactaa aaccggtcgg aagatcatac ctaccgccta tcacttccag
     7561 cgcacctcca taatccaaga tttcatcatc ctgctttaat tctccaagtt ccaatacatt
     7621 tttgatattt ttatcttggt tcttcgtggc gtatccatag ataaatttca gatagctgaa
     7681 ctgcttgaat ttaattttta cccattctga ataattgggc atagggatct cttgaggaaa
     7741 gtccggataa tccacattct ggacgatgat atggaattca tcgtttttca aagtatagtt
     7801 taatagagtg ccctcatata tatacagaaa ttgataatct ttttttggaa tggtataagt
     7861 tgtcatatta ttttaccttt tcaaaaacaa tgagtttaag attttttgag tccaagttgg
     7921 ttctactact cttatgaaat ttcagttgtt taaactcttc ctttaacaga ccattatatt
     7981 ttaaccttaa tcccactcga gccagttctg cttcatttgg aattcctctt aaatacttat
     8041 tgtttgatgt gccattaatc acaatttctc cccctttttt tgtaatacgt gctgcttcgg
     8101 gaaaataatc cattaaccgc tcaacatccc gcctcttcca aaaccgcgcg cgcggccaaa
     8161 tccgccgtat cttttttcaa cagcaggtgc aacgccctga aatcctgttg cagcgcggca
     8221 accttatcgg ggtgttcgta ccagtccgcc aacgccgccg ccagtttttc cggttttgct
     8281 tcagattgca ataattccgg cacagcctcc ttacccaaca ggatattcgg caggccgaca
     8341 tgcggcactt tgattttgcg tttcacataa gcataagtca gcggcgaaat cttgtagctg
     8401 atgaccatcg gacgcttgca caacgccacc tccaaagtcg ccgtaccgct cgttaccagc
     8461 accgcatccg ccgccctgca cactgtttca gactgtctgt cgattaccgt cagcggcaat
     8521 ccggcaaact ccggccgctg caaaacttcc gccaaacgcc gcttcgtcgc ctccgttgcg
     8581 gcaggcagca ggaagcatgc ggcaggatag cgttccaaca acaataatgc cgtctgaaaa
     8641 aacaccggcg ccatatagtc gatttcgctg acgcggctgc cgggcagcag ggcgaatacg
     8701 gggatgccgg catccacgcc caaagtttgc cgcgccgttt cacggtcgtc ttccaagggc
     8761 ataagctgcg ccatcggatg accgacaaac tccgcacgtc cgcccgcatc gagataaagc
     8821 tgcggctcca tcgggaacag gcacaacacg cggttgacct gatgcacgat tttgcccaca
     8881 cgttcccgcc gccacgccca caccgacggg ctgacataat gcacggtcgg aatccccgac
     8941 cgtttcagct tttccgccac acccaaatta aaatcgggcg catcgatacc gacaaagaca
     9001 tcaggtttca acgacagcaa atcccgtacc agccccctgc gtatccgtaa aatttccggc
     9061 agccgcctga ccacttcgac aaagccgcgc accgccagcc gctcctgatc ataaaggctc
     9121 tcgaaacctt ccgccttcat cagttcgccg ccgataccga caaaacgcgc ctgcggacaa
     9181 cgcttgcgga tggcgcgtat caggtgcgcc cccaataggt cgcccgacgc ttcgccgaca
     9241 ctgacggcaa tcaaagggct ttttttatca gccatattcg tctgtcccca catactttca
     9301 cgtcccgatg ccgtctgaag gcttcagacg gcatcggggt tcacattttc gtcccgtttt
     9361 ccaacatcac cgcaaactgc gccaagtccg gcggcagctc cgccttcaac accagcggct
     9421 cgcccgtgag cggatggttc aagtgcagct cggacgcgtg caaaaacatc cgcttcaaac
     9481 ccaacttctg caaacgacgg ttcgcctgat aatcgccgta gcgttcgtcg cccgcaatcg
     9541 gacagccttg agattgcagg tggacgcgga tttggtgcgt acgacccgtt ttcagcgttg
     9601 cccgcaccaa agtcaggtgc gacagcccga caccgtgcaa aatgccgtct gaaaaacggc
     9661 ttaacacacg gaacaccgtg tgcgccgact gcccgtcctc gctgacgcgt accatctttt
     9721 cgccttgtgc gccggtatat ttgaacaggg gcagtttgac atggaaattg tcgtccggca
     9781 gtttgcccac ccccagcgca aggtagattt ttttggggtg gtcgttacgg atggcttcgt
     9841 gaagtttgac gagcgcgctg cgtttcttcg ccaccatcaa caagccgctc gtatccttgt
     9901 ccaaacgatg aaccaactcc aaatacttcg cctccggacg ggcgcggcgc aactgttcga
     9961 taacgccgaa actcacgccg ctgccgccgt ggacggcaac gccggacggt ttgtcgatga
    10021 ccaaaagcgc atcgtcttcg taaacaacgt caaacgcacg cgccggtacg gcggcacgcc
    10081 tttcagacgg catttccttc tccgccacgc gcacaggcgg aatccgcacc gtatccccct
    10141 ccgcaatacg gctgtcgggt ttgcagcgtt tcttgttcaa ccgcacctcg ccggcgcgga
    10201 taatgcggtg gatatggctc ttgggaacac ccttgaggat ttttatcaga tagttatcaa
    10261 ggcgttgacc cgcctcatgt tcggcaaccc ctatcaagct gaccgaatct ttgcttattt
    10321 cgtgcgtttt catctataat ccgaacatcc gtttcagcaa aaagcgcgcc cgccgcgccc
    10381 ccctgaaacg gtttacttta aaacggaatt ttatattaaa aacgcactcc gcaaagcatt
    10441 ttccctgcgc ctgttcccag ccggcaggcg cagaacgtaa tcaagtttga attgattttg
    10501 ccgtttcggc gcggaagtta agacggcagc cgggccccaa gtcccaaacg caaaccgccc
    10561 aaaacacagg catcacgata acaagaagaa gccggccccc atttttccga ccgcagcgtt
    10621 cggaacgcgg cagacaaacc gccgcatcga tctttatagc cttctgtatc cgacccttcc
    10681 gcacacggtt ctccggaacg tgcatccctg cggattttca actcaaaaac tgattaccgg
    10741 ttttatccga aaacatcgga aaacccagcc ttacggaatg ccgaaccgga ccggcgcgcc
    10801 cgaatgccgc ccgtccacga ggtgatcatg aaaagaatgt tattcaacgc aacgcaggcc
    10861 gaagagctgc gcgttgccat cgtcgacgga caaaacctgc tggatttgga catcgaaacg
    10921 ctgggcaaag aacagcgcaa aggcaatatc tacaaaggca tcattacccg catcgagccg
    10981 tcgctggaag cgtgtttcgt ggattacgga accgaccgcc acggtttctt gccgtttaaa
    11041 gaagtctccc gctcatactt ccaagactac gaaggcggac gcgcgcgcat ccaagacgtg
    11101 ctcaaagaag gcatggaagt catcgtccaa gtcgaaaaag acgagcgcgg caacaaaggc
    11161 gcggcgctga ccaccttcat cagcctcgcc ggacgctatc tggtattgat gccgaacaac
    11221 ccgcgcggcg gcggcgtatc ccgccgtatc gaaggcgaag aacgtcaaga actcaaagcc
    11281 gctatggcgc aactcgacat tccgaacggc atgagcatca tcgcccgtac cgccggcatc
    11341 ggccgcagcg cggaagagtt ggaatgggat ttgaactatc tcaaacaact ctggcaggcg
    11401 attgaagaag caggaaaagc gcatcacgac ccttacctgc tctttatgga aagctcgctg
    11461 ctcatccgcg ccatccgcga ctatttccgc cccgacatcg gcgaaattct ggtggacaat
    11521 caagaagttt acgaccaagt tgccgagttc atgagctacg tcatgccggg caatataggc
    11581 cgtctgaaac tctacgaaga ccacacgccg ctgttttccc gcttccaaat cgaacaccaa
    11641 atcgaaagcg cgttttctcg cagcgtcagc ctgccttccg gcggcgcaat cgtcatcgac
    11701 cacaccgaag ccctcgtctc catcgatgtc aactccgcac gcgccactcg cggcgcagac
    11761 attgaagaca ccgcgttcaa aaccaatatg gaagccgccg aagaagtcgc gcgccaaatg
    11821 cgcctacgag acttgggcgg tttggtcgtc atcgacttca tcgacatgga aaaccccaaa
    11881 caccagcgcg atgtggaaaa cgtcctgcgc gacgcgctca aaaaagaccg cgcccgcgtg
    11941 cagatgggca aactctcccg cttcggcctt ttggaattga gccgccaacg cctgaaacca
    12001 gctttgggcg aaagcagcca cgtcgcctgt ccgcgctgcg ccggcaccgg cgtgattcgg
    12061 ggcatcgaat ccaccgccct gcacgttttg cgtatggttc aagaagaagc aatgaaagac
    12121 aacaccggcg aagtgcgcgc ccaagtgccc gtcgatgtcg ccaccttcct gttaaacgaa
    12181 aaacgcgccg agctgtttgc gatggaagag cgtttggatg tcaacgtcgt cctgattccg
    12241 aacatccacc tcgaaaaccc gcactacgaa atcaaccgca tccgcaccga cgacgtagaa
    12301 gaagacggcg aaccgagcta caagcgcgtc gccgagccgg aagaagacga atccgccaaa
    12361 cctttcggcg gcgaaaaagc caaagccgcc cgtcccgaac ccgccgtcaa aggcgtgcgc
    12421 cacaccagcc ccgccccgac tgccgccccc gagaaaaaaa cctcctggtg ggacagcttc
    12481 aaagcatggc tcaaacgcat tttcggcggc agcgaaaccc aagccgcgcc cgctgccgaa
    12541 acctccgaaa aacgcagcac ggcaaaccgc agcggcagcc gcgccaacaa ccgccgccaa
    12601 aacccgcgcc gcagcaaacg cgaaggcagc aaagtagaag tccgcgaagt ggcaggcaaa
    12661 actgccggac aggaagcgcg tgccgacaaa gccgaaacgc gcaacaacgg caaccgccgc
    12721 cgcaacgaac gcggcgaccg tgccgccgaa cgcgccaacg aagcggaaat ccaagaccgc
    12781 aacatacagc ctgccgcaac cgttgcagat gccgcaccgt ccgaaaccga agtgcaaacc
    12841 ggcaaacgcc gccgcaacgg cagccgcaac gaacgcggcc aaaccgcgct ggaaaccgcc
    12901 gccgttgccg aaacagccgt tcagacagcg gaaaacacgc cgtccgaacc gcataccgca
    12961 gaagacaaag gcagcaagcc caaatccgaa cgcaaccgcc gcgaacgcga cagccgcgac
    13021 gccaaagaac gccgcgagcg caacaatcag cgcgaccgcc gtcaaaacgg caaaaaacgc
    13081 aatatcccgt ctgccgccaa aatcgagcag tacctgaata ttcacgacac tgccgacaaa
    13141 gtccgttccg ccgccgcaca cgttttcgga gaaaccgacg caaacgcgcc gattaccgtc
    13201 agcattgccg atccgctcat cgccacaccc gttcagacgg catcttccgc cgtttcaaac
    13261 ggcgacgcac tggtttatga tgcggcagaa aaaatccgcc gtgccgccgc catcctgccc
    13321 gaaggcgcga caccgaaagc ctcagcacag gaaatgccgt ctgaaaccgc aacctttacg
    13381 gctgcggcgg aacaggcacg ggaaaccgca caaaccggcg gactcgtcct gatcgaaacc
    13441 gaccctgccg cattgaaagc atgggcggca caacccgaag tccaaaccgg acgcggtttg
    13501 cgccgttccg aacagcccaa gccgtctgaa gccgcaaccg tccctgccga agaaatgatc
    13561 caagtcgaaa cccggcaagg ctgaaccgac ggcggcaaaa agaggttctg ttccgcagaa
    13621 cctctttttt atatagattc ggatacctgc aatgccgtct gaaacttcgc cattcccgtg
    13681 attaccgaaa cattccgcca ttcccatgat tcccgcaaca ttccgtcatt cccgtgaaaa
    13741 cgggaatcta gaacctcaaa ctttcagata acctttgaat attgccgccg cccgaaggcc
    13801 tggattcccg cctgcgcggg aatgacggtt tagaagttgc ccgaaacctc aaaaaaaaac
    13861 cgaaaccgaa caagccggat tcccgcaaca ttccgtcatt cccgtgaaaa cgggaatcta
    13921 gaacctcaaa ctttcagata atctttgaat attgctgccg cccgaaggtc tggattcccg
    13981 caacattccg tcattcccgt gaaaacggga atctagaacc tcaaactttc ggataatctt
    14041 tgaatattgc cgtcgcccaa aggcctggat tcccgcctgc gcgggaatga cggcggaggg
    14101 tggacgatgc cgtctgaaac tgcgccattc ccatgattac cgcaaccttt cgtcattccc
    14161 gccacctttc gtcattcccg tgaaaacggg aatctagaac ctcaaacttt cagataatct
    14221 ttgaatattg ccgccgccca aaggtctgga ttcccgcctg cgcgggaatg acgatttgga
    14281 aattacccga aacccaaaaa caactgaaac cgaacagacc ggattcccgc ctgcgcggaa
    14341 atgacgggtc ttttatcatc tttaaaggct gccgcgcgcc atctcgacgg cggtctccac
    14401 ggcagttatc aggctgccgg aatccgccct gccggttgcc gccaaatcga gcgcggtgcc
    14461 gtgatcgacg gaggtgcgga taaagggcag ccccagcgtg atgttcacgc cctgtccgaa
    14521 gctgtggtat ttcaacacgg gcagcccttg gtcgtggtac atcgccaata cggcatccgc
    14581 accttcgagc ataaacggtt ggaacaaggt atccgccgga tacgggccgg cgaggtttat
    14641 cccttcgcgg cgcaggtttt ccaatgcggg gataatggtg tcggtttctt cgtgtccgag
    14701 gtgtccgctc tcgccggcgt gggggttgag tccggcgact aggattttgg gatttttgat
    14761 gccgaatttg tgttttaagt cgtgatgcaa aatgcgtgcg acgctttcaa tcagcggttg
    14821 cgtgatggcg gcggcaacgt ctttcagcgg caggtgggtc gttacgaggg cgacgcgcag
    14881 gcctttgccg gcaagcatca tcacaacctg ccccgtgccg cttttttccg ctagatattc
    14941 ggtgtgcccg ctgaaaaaac ctgtgcttgc gcgcgcgtcg ttgatgatgc ctttgtgcag
    15001 cggcgcggta acgatgccgt cgaaaatgcc gtctgaaatg cctgcgagcg cggtgtccaa
    15061 aagttgcagc acataggcgg cgttggcggg attgagccgc cctgccgcaa ccgcttcggc
    15121 ggtcggaatg tgcagcactt ccagctcgcc ttctccgggt gcgccgcctg attccggatc
    15181 gaagtcgcgc aagacgacgc ttttgcccaa ggcttcggcg cgcgcgcgca ataggttttt
    15241 gtcgcccaat accgcgcagc ggcagggcag gcgtgcaaac gccaagtcca aacaaatatc
    15301 ggggccgatg ccggcaggct cgccggaagt aacggcaaaa acaggctgtt tcatcgtgtt
    15361 tgctccaaac aaaatgcgat tctaacgccg cagccgcgcg gcgatgtaaa tttttctgat
    15421 tttgttgaca atctgctaga atgggcgttt acaaaattta aaccctgctt gcataccgcc
    15481 aatatgtgcg agtttcaact ttaaggaagc gatatgaacg agaactttac cgaatggctg
    15541 cacggctggg tcggcgccat caacgatccg atgtggtcat acttggttta tatgcttttg
    15601 ggtacggggc ttttcttcac cgtaaccacg ggctttgtcc aattccgcct gttcgggcgc
    15661 agcatcaaag aaatgctcgg cggccgcaaa cagggggacg accctcacgg catcacgccg
    15721 tttcaggcat ttgtaaccgg ccttgccagc cgcgtgggcg tgggcaatat cgcgggcgtg
    15781 gccatcgcca tcaaagtcgg cggaccgggc gcggtgtttt ggatgtgggt aaccgcctta
    15841 atcggtatga gttcggcgtt tgtcgaatct tcgctggcgc agctctttaa agtccgcgac
    15901 tacgacaacc accatttccg gggcggccct gcctactaca tcactcaagg gctggggcag
    15961 aaatggctgg gcgtgttgtt cgccctgagc ctgattttct gtttcggctt tgtgtttgaa
    16021 gcggttcaga ccaataccat tgccgatacc gtcaaagcgg cgtggggttg ggagcctcat
    16081 tatgtcggcg tcgccctggt gattttaacc gcgccgatta tcttcggcgg catcaggcgc
    16141 atatctaaag cggcggaaat cgtcgtcccc ctgatggcgg ttttgtacct ctttatcgcg
    16201 cttttcatca ttttgaccaa tattccgatg attccggacg tgttcggtca gattttttcg
    16261 ggcgcgttca aattcgacgc ggcagcaggc ggcttactcg gcggtctgat ttcgcaaacg
    16321 atgatgatgg gcatcaaacg cggcctgtat tccaacgagg cgggtatggg ttccgcgccg
    16381 aacgccgccg ccgccgccga agtgaaacac cctgtttcgc aaggtatgat tcaaatgctg
    16441 ggcgtgtttg tcgataccat catcgtttgt tcttgcaccg ccttcatcat cttgatttac
    16501 caacagcctt acggcgattt gagcggtgcg gcgctgacgc aggcggcgat tgtcagccaa
    16561 gtggggcaat ggggcgcggg cttcctcgcc gtcatcctgt ttatgtttgc cttttccacc
    16621 gttatcggca actatgccta tgccgagtcc aacgtccaat tcatcaaaag ccattggctg
    16681 attaccgccg ttttccgtat gctggttttg gcgtgggtct atttcggcgc ggttgccaat
    16741 gtgcctttgg tctgggatat ggcggatatg gcgatgggca ttatggcgtg gatcaacctt
    16801 gtcgccatcc tgctgctctc gcccttggcg tttatgctgc tgcgcgatta caccgccaag
    16861 ctgaaaatgg gcaaagaccc cgagttcaaa ctttccgaac atccgggcct gaaacgccgt
    16921 atcaaatccg acgtttggta aatcccgccc ttaccagagc cgcttccccg cgaagcggct
    16981 tttccctttc cgcacactgt aaaaacaggg cgaacaagcg tacaatccca accctttact
    17041 tttgaatcca tttcgttttt cagacggcat attgaatata gtggtttaac aaaaatcggg
    17101 acaaggcggc gaagccgcag acagtacaga tagtacagaa ccgattcact tggtacttca
    17161 gcaccttaga gaatcgttct ctttgagcta aggcgaggca acgctgtact ggtttttgtt
    17221 aatccactat aaatgccgtc tgaaacaccg tcaggcaata cacacatgac ccacatgatt
    17281 taccccaaaa cctacgacgt tatcgtcgtc ggcggcggac acgccggcac agaagccgcg
    17341 ctcgccgccg cccgtatggg cgcgcagacg cttttgctca cacacaatat tgaaacgctc
    17401 ggacaaatgt cgtgcaaccc ttccatcggc ggcatcggca aagggcattt ggtgcgcgaa
    17461 ctcgacgcgc tcggcggcgc gatggcgttg gcaaccgaca aatccggcat ccagttccgc
    17521 cgtctgaacg ccagcaaagg cgcggcagta cgggccacgc gcgcgcaggc ggatcgtatc
    17581 ctatataaag ccgccatccg cgaaatgttg gaaaaccaag aaaacctcga ccttttccaa
    17641 caagccgtcg aagacgtaac gctcgatggc gaccgcattt caggcgtaat caccgcgatg
    17701 ggcgtggagt ttaaagcacg cgccgtggtg ttgaccgcag gcacgttttt gtccggcaaa
    17761 atccacatcg gtttggaaaa ctacgagggc ggacgcgccg gcgaccccgc cgccaaatcg
    17821 ctgggcggac gtttgcgcga attgaacctg ccgcaaggcc gtctgaaaac cggcacgccg
    17881 ccgcgcatcg acggacgcac gattgacttc tcccaactga ccgaacagcc cggcgacacg
    17941 cccgttcccg tcatgtccgt acgcggcaac gccgaaatgc acccgcgcca agtgtcctgc
    18001 tggattacgc ataccaacac gcaaacccac gacatcatcc gctcaggctt cgaccgcagc
    18061 ccgatgttta ccggcaaaat cgaaggcgtg ggcccgcgtt attgtccgtc tatcgaagac
    18121 aaaatcaacc gcttcgccga caaagacagc caccagattt tcctagaacc cgaaggcctg
    18181 actacgcacg aatactaccc caacggtatc tccaccagcc tgccgttcga catccaaatc
    18241 gcgctcgtcc gcagtatgaa aggtttggaa aacgcccata tcctgcgccc cggctacgcc
    18301 atcgaatacg actacttcga tccgcgcaac ctcaaagcaa gcctcgaaac caaaaccatt
    18361 gccggattgt ttttcgccgg gcaaatcaac ggtacgacag gttatgaaga agccgccgcg
    18421 caaggactgc tggcaggcgc gaacgccgtg caatacgtcc gcgaacaaga cccgctcctg
    18481 ctgcgccgcg aacaagccta tctcggcgta ttggtggacg acctcatcac caaaggcgtg
    18541 aacgaaccct accgaatgtt caccagccgt gccgaatacc gcctgcaact cagggaagac
    18601 aacgccgata tgcgcctgac cgaagacggc tacaaaatcg gcttggtggg tgaagcgcaa
    18661 tggcgcatgt tcaacgaaaa acgcgaagcc atcgaacgcg aaatccaacg tttgaaaaca
    18721 acgtggtaca cgccgcaaaa actcgccgaa gacgaacaaa tccgcgtatt cgggcaaaag
    18781 ctcagccgcg aagccaacct gcacgacctc ctgcgccgcc cgaacctcga ctacgccgcg
    18841 ctgatgacgc tcgaaggcgc gatgccgtct gaacgcctct ccgccgaagt ggtcgaacaa
    18901 gtcgaaatcc aagtcaaata ccaaggctat atcgaccgcc aaaacgaaga aatcgacagc
    18961 cgccgcgaca tcgaaacctt aaagctgccc gaggatatcg attacagcaa agttaaaggt
    19021 ttgtcggcag aagtgcagca aaagctcaac cagcacaaac ccgaaaccgt cgggcaggca
    19081 agccgcattt ccggcgtaac ccctgcggca gtggcattgc tgatggtgca tttgaagcgc
    19141 gggtttaaag acgcgaaata aacacatcgg cgcgatgccg tctgaaacac cgttcagacg
    19201 gcatcgcgcc atcccgacag gaaacatcat gcacatactg accgccggcg tggacgaggc
    19261 agggcgcggg cctttagtcg gcagcgtgtt tgccgccgcc gtcatccttc cggaaatatt
    19321 cgacctgccc ggactgaccg actccaaaaa actcagcgag aaaaaacgcg acgcgcttgc
    19381 cgaaatgata aaaaatcagg cggttgcgtg gcacgttgcc gccgcctcgc ccgaagaaat
    19441 cgccagcctc aacatcctgc acgccaccat gctcgcgatg aaacgcgccg ttgacggttt
    19501 ggctgtgcgt cccgaaagaa tattcatcga cggcaaccgc attcccgaac atttgaacat
    19561 ccctgccgaa gccgtcgtca aaggcgacag caaaatcatc gaaatctccg ccgcatccgt
    19621 tttggcaaag accgcacgcg atgcagaaat gtacgcactg gcgcaacgcc atccccaata
    19681 cggtttcgac aaacacaaag gttacggcac gaagcagcat ctagaagccc tcaaacaata
    19741 cggcgtgctg cccgaacacc gccgagactt cgcccccgtc agaaacctgc tcgcgcagca
    19801 ggccttgttt taaaccggca caaaaatgcc gtctgaactt cagacggcat tttcagcatc
    19861 gcaacttcaa agagaaagaa cccaaaccgt cattcccgcg aaaaatagaa aatcaaaaaa
    19921 aaacctaaaa tccgtcattc ccgcgcaggc gggaatccaa tccgtccggt ttccgttttt
    19981 tttgaatttc aggtaacttc caaaccgcca ttcccgcaaa agcgggaatc tagaaactca
    20041 aagctgcaag aatttatcaa aaatgactga aactcaaaaa accggattcc cgcgaaaaca
    20101 ggaatccgga gtctcagggt tggaaaaacc gtttttcccg ataagtttcc gtaccgacag
    20161 acctagattc ccgcctgcac gggaatgacg atatttcagt tttgtgtttt tgattttttt
    20221 gtttttgcgg gaatgacgat atagtggatt aacaaaaatc aagacaaggc gacgaagccg
    20281 cagacagtac agatagtacg gaaccgattc acttggtgct tcagcacctt agagaatcgt
    20341 tctctttgag ctaaggcgag gcaacgccgt actggttttt gttaatccac tataaatgac
    20401 gatataagta tttttatttt aatccgccat attaacgcac ccggccaaac agcataaagg
    20461 cacgggcagc ccgatttgga ttgacctatt tccccgacac cctcgccgcc agctcgtccg
    20521 ccaaggcaag atacgccttg gtaccctttg cctgcgcatc ataagccatc accggcatac
    20581 cgtggctcgg cgcttccgca aggcggatat tgcgcgggat gacggtttca aacagcaaat
    20641 ccccgaaatg gctgcgcaac tgttcgctga cttcggcaac cagcctgctg cggctgtcgt
    20701 acatcgtgcg cacgatgccc gtgatgtcca aatcgggatt gaccgcctga cgaattttgc
    20761 gcacggtcgc aatcaaatcg gaaatccctt ccagcgcgta atattcgcac aacatcggca
    20821 caatcacgcc gccggctgcc accagcccgt taagcgtcaa cagcgtcagc gaaggcgggc
    20881 agtcgatcag gataaagtcg taatcttccg ccactgcctt gagcgcgttt ttcaaacgca
    20941 cttcccgggc gatttcctgt accaactcga tttccgcgcc ggccagcgcg cggttcgcac
    21001 ccaacacagc gtatccgccc tctttgctgc gtaccgccgc cgactgcacg tccgcatcgc
    21061 ccaataagac ctgataaacg ccggactgca aactcgcctt gtcgatgccg ctgcccgtcg
    21121 tcgcattgcc ctgcggatcc aaatcgacca ccagcacgcg tttgccgcgc gatgccagcg
    21181 aagccgccaa atttaccgtc gtcgtcgttt tgcccacacc gcccttctga ttggcgatgg
    21241 caaggatgtt cgcactcatg tcccgcccgt gtcccgtctg atgttgaaaa aagaaaaaca
    21301 gtgcggaatt ttacctttat ccgcacaaaa aaggtattca tgccgtctga agcgcgctca
    21361 acgcttgcgg agtatgacga tatggcgttc cgcatccaag cccggcacgt caagcctttg
    21421 gactttttcg acgcacacat cctgcggcag gtggtcgatt tccccctgcg gatacacgcc
    21481 cttcatcgcc gcccagtagc cgccgtcttt caacagatgc accgtccacg acacaaaatc
    21541 cgccagttct gcaaacgcac ggctggtaac cacgtcggca cgcacgtccg aaaccgcctc
    21601 cacgcgtccg gataccacgc gcacattgtc caaccccaac tcgataaccg cctgctgtaa
    21661 aaaagccgtt ttcttcgtat tcgcatccaa aagggttatc tgcacatccg gacggcacac
    21721 cgccgccgga atgccgggct gaccgccgcc cgaaccgaca tccagcatcg tttgcacacc
    21781 ctcgatatgg ggcagcagcg tcaggctgtc caaaagatga tggacaatca ttttttcctc
    21841 gtcgcgcagg gcggtcagat tgtaggtttt gttccacttt ttcaacaaat ccacataggc
    21901 caaaagcctg tcctgcgccg tttccgaaat atccagcccc atcgcggcaa tgcctgattg
    21961 caggcgttct ttgcgttcca tatctgcttc ctgtccatat tcaggcgtaa tgttaacgga
    22021 aaaacatgcc gtctgaaacc gcgtgtcggg gttcagacgg catttcccgt tccaacctat
    22081 tttttcctgt gaaacaccac cggctgcacc ggcgcgcgcg tcaggcgttt gggcagcgtc
    22141 agcatcgcca ccagccacac ggcaaacgca tattccaaca ccgcctcccc acgcagcccg
    22201 cccaaagccc cactgccaag cagcagctcg aaaatccaag ccaccgctgc cgccgcgcaa
    22261 gccgccacgc ccgacagaaa cagcgcgtaa cgggaatgcc gccgcatcat ctttttgtac
    22321 gccagcttcg tcaggcctgc cgacacgacc aggttcaaaa acgcaaacac accgaacaca
    22381 aaccaaacag taccgtccca accgccacgc cggccgacac cgacaccagc agccctgccc
    22441 gtccgaacgc aagcgcaaag gcatcatgca ccgccaacgc aaacggcaac gtcaaaaaca
    22501 ccagccccgc aaacagagcc gcataaggat ctttctcgtt cacaaacatc gccgtccccc
    22561 tcttccgaag cagaccgcat tataccgcgc actgccttgc cgcccgccag aaaagttgca
    22621 caaacaaccg ttcatatata tcataacgaa aaaacgccgg tgtagctcag tcggtagagc
    22681 agcgcattcg taacgcgaag gtcgggggtt cgattccctt ctccggcacc aataccaagc
    22741 acagaccctc ccttcctcgg gaagcctgtg ctttttcaca tttccgcttc agacggcaac
    22801 cgatatgaac acctcgcaac gcaaccgcct cgtcagccgc tggctcaact cctacgaacg
    22861 ctaccgccac cgccgcctca tacacgccgt gcggctcggc ggggccgtcc tgttcgccac
    22921 cgcactcgcc cggctgctcc acctccaaca cggcgaatgg ataggcatga ccgtcttcgt
    22981 cgtcctcggc atgctccagt ttcaaggggc gatttactcc aaggcggtgg aacgtatgct
    23041 cggcacggtc atcgggctgg gcgcgggttt gggcgtttta tggctgaacc agcattattt
    23101 ccacggcaac ctcctcttct acctcaccgt cggcacggca agcgcactgg ccggctgggc
    23161 ggcggtcggc aaaaacggct acgtccctat gctggcgggg ctgacgatgt gcatgctcat
    23221 cggcgacaac ggcagcgaat ggttcgacag cggcctgatg cgcgcgatga acgtcctcat
    23281 cggcgcggcc atcgccatcg ccgccgccaa actgctgccg ctgaaatcca cactgatgtg
    23341 gcgtttcatg cttgccgaca acctgaccga ctgcagcaaa atgattgccg aaatcagcaa
    23401 cggcaggcgt atgacgcgcg aacgtttgga gcagaatatg gttaaaatgc gccaaatcaa
    23461 cgcacgcatg gtcaaaagcc gcagccacct cgccgccaca tcgggcgaaa gccgcatcag
    23521 ccccgccatg atggaagcca tgcagcacgc ccaccgtaaa attgtcaaca ccaccgagct
    23581 gctcctgacc actgccgcca agctgcaatc tcccaaactc aacggcagcg aaatccggct
    23641 gcttgaccgc cacttcacac tgctccaaac cgacctgcaa caaaccgtcg cccttatcaa
    23701 cggcagacac gcccgccgca tccgcatcga caccgccatc aaccccgaac tggaagccct
    23761 cgccgaacac ctccactacc aatggcaggg cttcctctgg ctcagcacca atatgcgtca
    23821 ggaaatttcc gccctcgtca tcctgctgca acgcacccgc cgcaaatggc tggatgccca
    23881 cgaacgccaa cacctgcgcc aaagcctgct tgaaacacgg gaacacggct gacggtcgga
    23941 cacgatgccg tctgaaacgc ctgccgcttc agacggcatc cccaatccgc ctgccttgtc
    24001 gtcatgcccg aataacggta ctattcgcag ttaacagttt tcatgccgtc tgaaaggttt
    24061 gaagcgcgtt tcagacggct gcccgcccac cttatcccac cgaaagaaca atatgattaa
    24121 cgatattcaa aaaacagccg aaggcaaaat gcagcgttcg gtcgaagtac tgaaagaaaa
    24181 tctggcgaaa gtgcgtaccg gccgcgcgca taccggtctg ctcgaccaag tggaagtcga
    24241 atactggggc agcatggttc ccgtcagcca agttgccaac gtaacgcttc tggacgcgcg
    24301 caccatcggc gtgaaaccgt ttgagggcaa tatggcggcc aaagtcgaga aagccatccg
    24361 cgattcaaac ttgggactga acccggcagc tgtcggcgac ctgatccgcg tgccgatgcc
    24421 catgctgacc gaggaacgcc gcaaagacct gattaaagtc gtacgcggcg aagcggaaga
    24481 aggccgcgtc tctatccgca acgtgcgccg cgatgccaac gaccacatca aaaaactcct
    24541 caaagacaaa gaaatttccg aagacgaggc acgtcgcggc gaagaagcgg ttcaaaaact
    24601 gaccgacaaa tacattaccg aagccgacaa actcctgact gccaaagaag aagatttgat
    24661 ggcaatttaa cctgcacggt tcggcgttca gacggcattt gaatgccgaa ccgcgaaagg
    24721 cagacatgaa aagcagcacg caggccgttt tggaacacac cgccattccc aagcatatcg
    24781 ccgtgattat ggacggcaac ggccgttggg cgaaaaaacg tttcctcccg cgcataatgg
    24841 gacacaaacg cggtttggac gcattggaaa atatggtgaa gcattgcgcc aaactgggtg
    24901 tgcaatatct gaccgtgttt gccttttcaa ccgaaaactg gcgccgcccc gaagacgaag
    24961 tttcgttcct gatggggctg tttttacagg ctttgcaaaa acaggtacgc cgtctgcacg
    25021 aaaacaatat gcgcctgaaa atactgggca gccgcgaacg cttcagccgt caaatcctga
    25081 agggcatcga agaagcggag gcgttgacag caaacaatac cggtctgacc ctgagcattg
    25141 ccgccgatta cggcggcaga tgggatattt tgcaggcggc aaacaaactg attgccgaag
    25201 gcgtatccga gattacggaa gacacgctgg cgaaacactt gatgctgggc gatgcaccgg
    25261 aaccggattt gttcatccgc accggcggcg aaacgcgcat cagcaatttc ctgctctggc
    25321 agatggcata tgcagaactg tatttcaccg atattttgtg gcccgatttt gacggcaagg
    25381 ctttggacga tgccgtcgct tcgttccaaa aacgcgaacg gcggttcgga cgcacctccg
    25441 agcaactgcc tatcgaacag caaaggaact gaatatgctg aaacaacggg tgataactgc
    25501 tatgtggctg ctgccgctga tgctgggcat gctgttttac gcgccgcaat ggttgtgggc
    25561 tgcattttgc ggactgattg ccctgattgc cttgtgggaa tatgcccgta tgggcggttt
    25621 gtgcaaaatt aaaaccaacc attacctcgc cgcaaccttg gttttcggcg tggttgccta
    25681 tgcgggcggc tggatgctgc ctaatttggt ttggtatgtt gttttggcat tttggctcgc
    25741 cgttatgcct ttatggttga gattcaaatg gaggctcaac ggcggttggc aggtttatgc
    25801 cgtcggctgg cttctggtca tgccgttttg gttcgcgctc gtatccctgc gcccgcatcc
    25861 cgatgatgcc ctgccgctgc tcgccgtgat gggtctggtc tgggttgccg acgtttgcgc
    25921 gtatttcagc ggcaaggcgt tcggcaaaca caaaatcgcg ccggcaatca gccccggaaa
    25981 aagctgggaa ggcgcaatcg gcggcgcggt ttgcgtggcc gtgtacatga ccgccgtacg
    26041 aagtgccggc tggctggcat tcgatacagg ctggttcgat accgtgttaa tcggtttggt
    26101 gttgaccgtt gtcagcgtat gcggcgacct tttggaaagc tggctcaagc gcgcggcagg
    26161 catcaaagac agcagcaacc tgctgcccgg acacggcggc gtgttcgacc gtaccgacag
    26221 cctgattgcc gttatcagcg tctatgcggc gatgatgtcg gttttaaatt gattctatgc
    26281 cgtctgaaaa cgcttcagac ggcatccggt ataaagttat ccccattatg acaccacaag
    26341 tcctgaccat attaggcagt accggcagca taggcgaaag cacgctggac gttgtctccc
    26401 tccaccccga aaaattccgc gtattcgcgc tggcagggca taagcaggtc gagaaactgg
    26461 cggtgcaatg ccggacgttc cgccccgaat atgccgtcgt tgccgatgcc gaacacgccg
    26521 cccggcttga agctttgttg aaaggcgacg gcacggcgac gcaggtttta cacggcgcgc
    26581 aggcattggt tgacgttgcc tctgccgacg aagtcagcgg tgtcatgtgc gccatcgtcg
    26641 gggcggtggg gctgccttcc gcgctcgcag cggcgcaaaa aggcaaaacc atttatctgg
    26701 cgaacaaaga gacgctggtg gtttccggcg cgttgtttat ggaaaccgcc cgtgcaaacg
    26761 gcgcggcagt gctgcccgtc gacagcgaac acaacgccgt tttccaagtt ttgccgcgcg
    26821 attacgccgg ccgtctgaac gaacacggca tcgcttcgat tatcctgacc gcttccggcg
    26881 gcccgtttct gaccgccgat ttaaacacgt tcgacagcat tacgcccgac caagcggtca
    26941 aacaccccaa ttggcgtatg ggacgcaaaa tctccgtcga ttccgccacc atgatgaaca
    27001 aaggtttgga gctgattgaa gcgcattggc tgttcaactg tccgcccgac aaactcgaag
    27061 tcgtcatcca tccgcaatcc gtgatacaca gcatggtgcg ctaccgcgac ggctccgtgt
    27121 tggcgcaact gggcaatccc gatatgcgaa cgcccatcgc ttattgtttg ggtttgcccg
    27181 agcgcatcga ttcgggtgtc ggcgacctgg atttcgacgc attgtccgcg ctgaccttcc
    27241 aaaagcccga ctttgaccgc ttcccctgcc tgaagctcgc ctatgaagcc atgaacgcgg
    27301 gcggggtcgc gccctgcata ttgaacgccg ccaacgaagc cgccgtcgcc gcctttttgg
    27361 acggacagat taagtttacc gacattgcca aaaccgtcgc ccattgtctt tcacaagact
    27421 tttcagacgg cataggcgac ataggggggc tcttggcgca agatgcccgg acacgcgcac
    27481 aagcgcgggc atttatcggc acactgcgct gatgccgtct gaacaccgtt atcaaaggaa
    27541 aaccatttgc acacccttct agcttttatc ttcgccatcc tgattttggt cagcctgcac
    27601 gagttcggac actacatcgt tgccagattg tgcggcgtca aagtcgtacg cttttccgtc
    27661 ggcttcggca aaccgttttt cacccgaaag cgcggcgaca ccgaatggtg cctcgccccg
    27721 attccgttgg gcggttacgt caaaatggtc gacacgcgcg aaggcgaagt atcagaagcc
    27781 gatttaccct acgcttttga caaacaacac cccgccaagc gcatcgccat cgtcgccgcc
    27841 ggcccactga ccaacctcgc actggcggtt ttgctgtacg gactgagctt ttccttcggc
    27901 gtaaccgaac tgcgccccta cgtcggcaca gtcgaacctg acaccattgc cgcccgcgcc
    27961 ggcttccaaa gcggcgacaa aatacaatcc gtcaacggca cacccgttgc agattggggc
    28021 agcgcgcaaa ccgaaatcgt cctcaacctc gaagccggca aagtcgccgt cggcgttcag
    28081 acggcatcgg gcgcgcaaac cgtccgcacc atcgatgccg caggcacgcc ggaagccggt
    28141 aaaatcgcaa aaaaccaagg ctacatcgga ctgatgccct ttaaaatcac aaccgttgcc
    28201 ggcggcgtgg aaaaaggcag ccccgccgaa aaagcaggcc tgaaaccggg cgacaggctg
    28261 actgccgccg acggcaaacc catcgcctca tggcaggaat gggcaaacct gacccgccaa
    28321 agccccggca aaaaaatcac cctgacctac gaacgcgccg gacaaaccca taccgccgac
    28381 atccgccccg atactgtcga acagtccgac cacaccctga tcgggcgcgt cggcctccgt
    28441 ccgcagccgg acagggcgtg ggacgcgcaa atccgccgca actaccgtcc gtctgttgtc
    28501 cgcgcattcg gcatgggctg ggaaaaaacc gtttcccact cgtggacaac cctcaaattt
    28561 ttcggcaaac taatcagcgg caacgcctcc gtcagccata tttccgggcc gctgaccatt
    28621 gccgacattg ccggacagtc cgccgaactc ggcttgcaaa gttatttgga atttttggca
    28681 ctggtcagca tcagcctcgg cgtgctgaac ctgctgcccg tccccgtttt ggacggcggc
    28741 cacctcgtgt tttatactgc cgaatggata cgcggcaaac ctttgggcga acgcgtccaa
    28801 aacatcggtt tgcgcttcgg gctcgccctg atgatgctga tgatggcggt cgccttcttc
    28861 aacgacgtta cccggctgct cggttagatt ttacgtttcg gaatgccgtc tgaaaccgca
    28921 ttccgcacca caaggaactg acaatgaaac tgaaacagat tgcttccgca ctgatggtct
    28981 tgggcatatc gcctttggca cttgccgact tcaccatcca agacatccgc gtcgaaggct
    29041 tgcagcgtac cgagccgagt accgtattca actacctgcc cgtcaaagtc ggcgacacct
    29101 acaacgacac acacggcagt gccatcatca aaagcctgta cgccaccggt ttctttgacg
    29161 acgtacgcgt cgaaactgcg gacgggcagc tcctgctgac cgttatcgaa cgccccacca
    29221 tcggctcgct caacatcacc ggcgcaaaaa tgctgcaaaa cgacgccatt aagaaaaacc
    29281 tcgaatcgtt cgggctggcg cagtcgcaat actttaatca ggcgacactc aatcaggcag
    29341 tcgccggcct gaaagaagaa tacctcgggc gcggcaaact caatatccaa atcacgccca
    29401 aagtaaccaa actcgcccgc aaccgcgtcg acatcgacat cacgattgac gagggcaaat
    29461 ccgccaaaat caccgacatc gaatttgaag gcaaccaagt ctattccgac cgcaaactga
    29521 tgcggcagat gtcgctgacc gaaggcggca tttggacatg gctgacacga agcaaccaat
    29581 tcaacgagca gaaatttgcc caagacatgg aaaaagtaac cgacttctac cagaacaacg
    29641 gctacttcga tttccgcatc ctcgataccg acatccaaac caacgaagac aaaaccaagc
    29701 agaccatcaa aatcaccgtc cacgaaggcg gacgtttccg ttggggcaaa gtctccatcg
    29761 aaggcgacac caacgaagtc cccaaagccg aactggaaaa actgctgacc atgaagcccg
    29821 gcaaatggta cgaacgccag cagatgaccg ccgttttggg tgagattcag aaccgcatgg
    29881 gctcggcagg ctacgcatac agcgaaatca gcgtacagcc gctgccaaac gccgaaacca
    29941 aaaccgtcga tttcgtcctg cacatcgaac cgggccggaa aatctacgtc aacgaaatcc
    30001 acatcaccgg caacaacaaa acccgcgacg aagtcgtgcg ccgcgaattg cgccaaatgg
    30061 aatccgcgcc ttacgacacc tccaagctgc aacgctccaa agagcgcgtc gagcttttgg
    30121 gctacttcga caacgtacag tttgatgccg tcccgcttgc cggcacaccc gacaaagtcg
    30181 atttgaacat gagcctgacc gaacgttcca ccggctcgct cgacttgagc gcgggctggg
    30241 tacaggatac cggcctggtc atgtccgcag gcgtttccca agacaacctg ttcggtacgg
    30301 gcaagtcggc cgccctgcgc gcctcacgaa gcaaaaccac gctcaacggc tcgctgtcgt
    30361 ttaccgaccc gtacttcacg gcagacgggg tcagcctagg ctacgatgtt tacggaaaag
    30421 ccttcgaccc gcgcaaagca tcgaccagca tcaaacaata taaaaccacc acggcaggcg
    30481 caggcatccg catgagcgtg cctgttaccg aatacgaccg cgtgaatttc ggtttggtgg
    30541 cagaacacct gaccgtcaac acctacaaca aagcgcccaa acactatgcc gactttatca
    30601 aacaatacgg caaaaccgac ggcacagacg gcagcttcaa aggctggctg tacaaaggta
    30661 ccgtcggctg ggggcgcaac aaaaccgaca gcgcgttatg gccgacgcgc ggctacctga
    30721 cgggcgtgaa cgccgaaatc gccctgcccg gcagcaaact gcaatactac tccgccaccc
    30781 acaaccaaac ctggttcttc cccctgagca aaaccttcac actgatgctt ggcggcgaaa
    30841 tcggctatgc caacggctac ggcaaaacca aagaaatccc cttctttgaa aacttctacg
    30901 gcggcggcct gggttcggta cgaggttacg aaagcggcac acttggtccg aaagtctatg
    30961 acgaatacgg cgaaaaaatc agctacggcg gcaacaaaaa agccaacgtc tccgccgagc
    31021 tgctcttccc gatgcccggc gcgaaagacg cgcgcaccgt ccgcctgagc ctgtttgccg
    31081 acgcaggcag cgtgtgggac ggcaaaacct acgacgacaa cagcagttcc gcgaccggcg
    31141 gcagggttca aaacatttac ggcgccggca atacccataa atccaccttt accaacgaat
    31201 tgcgctattc cgccggcggc gcggttacct ggctctcgcc tttaggcccg atgaaattca
    31261 gctacgccta cccgctgaag aaaaaaccgg aagacgaaat ccaacgcttc caattccaac
    31321 tcggcacgac gttctaatcc cgcaaatgcc gtctgaagcc cttcagacgg catttcgcgg
    31381 caacattcga aggagtttta ccatgacccg tttgacccgc gcgtttgccg cggctctgat
    31441 cggtttgtgc tgcaccgcag gcgcgcacgc cgacaccttc caaaaaatcg gctttatcaa
    31501 caccgagcgc atctacctcg aatccaagca ggcgcgcaag attcaaaaaa cgctggacag
    31561 cgaattttcc gctcgtcagg acgaattgca aaaactgcaa cgcgaaggtc tggatttgga
    31621 aaggcagctt gccgaaggca aactcagaaa cgcaaaaaag gtgcaagccg aagaaaaatg
    31681 gcgcgggctg gtcgcagcgt tccgcaaaaa acaggcgcag tttgaagaag actacaacct
    31741 ccgccgcaac gaagagtttg cctccctcca gcaaaacgcc aaccgcgtca tcgtcaaaat
    31801 cgccaaacag gaaggttacg atgtcatttt gcagaacgtg atttacgtca acacccaata
    31861 cgacgttacc gacagcgtca ttaaagaaat gaacgcccgc tgaccctttc agacggcata
    31921 ccgaacagga aaaccatgat tccggccacc tacaccctgt cccaaatcac cgcgcggctc
    31981 ggcggcgaat ggcgcggcga ggacatttcc gttaccgccg tgcgcccgct cgcagacgcg
    32041 caggcggaac acatcagctt ccttgccaat ccgaaataca aagccgaagt ccacgacagc
    32101 agcgcgggcg cggtcatcgt ttccgccaaa gcggcagacg gatttgaagg gcgcaacctg
    32161 attgtcgccg acgaccccta tctctatttc gccaaagtcg cgcgcctgtt ttcacccgtc
    32221 gtcaaagcgc gcggcggcat ccatccgacc gccgtcgtcg aaccgggcgc gaccgtcccc
    32281 gcaagctgcg aaatcggtgc gaacgcctac atcggcgcga acaccgtact cggcgaaggc
    32341 tgccgcatct tggcaaacgc cgtcgtccaa cacgattgca gactgggcga cgaagtcgtc
    32401 ctgcatccca acgccgtcgt ttattacggc tgcacactcg gcagacgcgt cgaaatccac
    32461 agcggcgcgg tcatcggcgc ggacggtttc ggactcgcct ttgccggcga ttcgtggttc
    32521 aaaatcccgc aaaccggcgc ggtaacgctg ggcgacgacg tagaaatcgg ctcgaacacc
    32581 aacatcgacc gcggcgcgat gagcgacacc accgtcggca acggcaccaa aatcgacaac
    32641 caagtccaaa tcgggcacaa ctgcaaaatc ggttcgcaca ccgtcatcgc cgccaaaacc
    32701 ggcatctccg gcagcgtaac cataggcagc tactgcatca tcggcggcgg ggtcggtacg
    32761 gtcggacaca tcgaaatcgc cgacaaaacc accatcggcg gcggcacgtc cgtcacccac
    32821 agcattaccg aaagcggcaa acacctcgcc ggcatcttcc cgatgtccac ccataaagaa
    32881 tgggcgcgca acgccgttta catccaccgc ttaagcgaaa tgaacaaacg cctcaaaaca
    32941 ctggagcagc agctttcaga tgccggtcaa gacagcaaat aaccaaaccg actttattca
    33001 aggaatacga cgaacatgga cgtacaactc cccatcgaag ccaaagacat ccaaaaactc
    33061 atcccccacc gctatccgtt tctccagctc gaccgcatca ccgccttcga gccgatgaaa
    33121 accctgaccg ccatcaaaaa cgtaaccata aacgaaccgc agttccaagg ccactttccc
    33181 gacctgcccg tgatgcccgg cgtactcatc atcgaagcga tggcgcaggc gtgcggcacg
    33241 ttggcgattt tgagcgaggg cgggcgcaaa gaaaacgaat tcttcttctt cgccggcata
    33301 gacgaagccc gcttcaaacg ccaagtcatc cccggcgacc aactcgtctt tgaagtcgag
    33361 ctgctgacca gccggcgcgg catcggcaaa ttcaacgccg ttgccaaagt ggacgggcaa
    33421 gtcgccgtcg aagccatcat catgtgtgcc aaacgcgtgg tttgagtgtt cagaaaaagg
    33481 tcgtctgaaa gtttcagacg acctaataaa aagaaaaccc accggtttag gtttattcaa
    33541 acccagggac acggtgggga ttagttttac ctaactgtat caaatatagt ttgaaacgtc
    33601 aatttaaaaa taaagaatca ggtgttagcg tggattataa ggaatgctgt agtatttttt
    33661 ctgatttcag aatggaacgg tataaaaatg ccgttgggga agacaaagca gctgaattgt
    33721 atttattgaa tttatcttta tcaagagaac tttttcatgt tgtttcaata tttgagattg
    33781 ttttaagaaa caaaattgac atttgccttc agcaggcgtt taaagacaga aactggttat
    33841 ataacagcat acagccacag acgaatcccg cattaaaata tcaaggttgc tttttaagaa
    33901 atggcacgaa agaatctgct gaattaatca aggttgcatt atctaaaata caaaataata
    33961 gcgggggaaa gtttgaccac aaccaattgg ttgcaggact aggattcggt ttttggcggt
    34021 atctgtttgc aggagggaaa gatgcccaat ttgatgttac agggaaagta ttgatgaaag
    34081 tttttccaaa aaagcccaaa tctacaccaa gtgtgcaata taaccaaaaa tggatttttc
    34141 gagaactttc caatattaac aaattccgta atcgtttggc acatcacgag ccgatttgtt
    34201 ttaaaggtgc aataaaagat accaactacg ctagaaatat tcaccaatct atttttgaac
    34261 tgcttaatta catggatgta gatactgctt cagtatttag ccattttagc gatcaagtga
    34321 ttgcggtctg cgatgaaatc gacaaactgt aattttctat tatttgtctt aacaagcagc
    34381 ggagtattca aaacatgacc ctcatccacc cgaccgccgt catcgacccc aaagccgaac
    34441 tcgactccgg cgtcaaagtc ggcgcgtaca ccgttatcgg ccccaacgtc caaatcggtg
    34501 cgaataccga aatcggtccg cacgccgtca tcaacggcca caccagcatc ggcgaaaaca
    34561 accgcatttt ccaatttgcc agcctcggcg aaattccgca ggacaaaaaa taccgcgacg
    34621 agccgaccaa gctgattatc ggcaacggta acaccatccg cgaattcacc acctttaatt
    34681 taggcacggt aaccggcatc ggcgaaaccc gtatcggcga cgacaactgg attatggcgt
    34741 actgccacct cgcgcacgac tgcgtggtcg gcaaccacac catcttcgcc aacaacgcct
    34801 cgcttgccgg acacgttacc gtcggcgact acgtcgtttt gggcggctac acgctggttt
    34861 tccaattctg ccgcatcggc gactacgcca tgaccgcgtt tgccgcaggc gtacacaaag
    34921 acgtgccgcc ctactttatg gcatcgggct accgcgccga accggcgggg ctcaacagcg
    34981 aaggcatgcg ccgcaacggt tttaccgcag agcagatttc cgccgtcaaa aacgtgtaca
    35041 aaaccctcta ccatcgcggc attccgtttg aagaggccaa ggcagacatc ctccgccgcg
    35101 ccgaaaccca agccgagctt gccgtattcc gagacttttt cgcacaatcg acgcgcggca
    35161 tcatccgctg accgtatcct tttgatgccg tctgaagccc cgaaagcgtt tcagacggca
    35221 tcggtttttt taaagcggta tattgtttga tcgatgcatc attttgtaga tttcagaagt
    35281 atggcagtcg gcagcattga tgatttctgc cgcccgccac atccccattc ggacatttca
    35341 ttgtgacctc cgccgctgct tttaaagaat tgcaaacaat ttccgcagct tgaaccgacc
    35401 tgctttcggc gaaaaaacca aaagtatttt tcaaaagaac atattgtctt attgaatatt
    35461 ctgtgctgaa attataggac actacaaaag tggtgtttta aaaataaaac agacaaagga
    35521 gaaagccatg caattgtttt tagacaatct caaagccttt ttcgaaaccg tcagcggctg
    35581 ggtctgggga tctgttatgt tgatgctgct ggtcggcacg ggcattgtgc tgaccgtttt
    35641 gctgaaaggc ttgcagttca ctatgttggg ctatgcgctg aaacaggcgt ttgtgccgtc
    35701 aaagaagtat gaaggcggcg aaggccacga aggcgatatt tcccattttg cggcgttgat
    35761 gaccgcgctg tccgccacca tcggtacggg caacatcgcc ggcgtggcga ctgcggtggt
    35821 aaccggcggc ccgggcgcgg tattttggat gtggataacc gccattttcg gtatggccac
    35881 caaatacggc gagggcgtgt tggcggtgaa ataccgcgtc aacaattcca aaggcgaaat
    35941 gtccggcggc ccgatgtatt acatcgaaaa aggcttgggc aaaaactgga aatggatggc
    36001 cgttgcattt gcgctgttcg gcacattcgc ttccttcggt atcggcagct cggtgcagtc
    36061 caactcggtt gcacaggcgg tgcaaaccag cttcggtatc gaacctgcct ataccggcat
    36121 tacgttgacc gttctgactg ccgttgtcgt tttaggtggt attaaaggca tcgccaaagc
    36181 cgcttctttc atcgtgcctg ctatggcggt gttttatgtg ttgggcggtc tttccattat
    36241 cgcgattaat tccgatgcac tgatgcctgc cgtcaagctg attttctccg atgcgttcag
    36301 cgcgcaggca gtggcgggcg gcgctatcgg tacggtcatc cgctacggcg tggcgcgcgg
    36361 cgtgttctcc aatgaggcgg gtatgggttc tgcgcctatt gccgccgcag ccgcgaaaac
    36421 cgaccatccc gtccgtcagg ccttggtttc tatgaccggt acgtttttgg ataccatcgt
    36481 cgtttgctcg attaccggca tcgtgttggt aatgggactg ctcggcgcgg gcggcgagtt
    36541 tgtcaaacct gaagtgagcg gcgcggcact gacaaccgtc acattccaaa aaatgctgcc
    36601 cggcatcggc ggctggattg ttaccatcgg cctgattttc tttgcctact caaccattct
    36661 cggctggtgc tattacggcg aaaaatgcgc ggtgtatgtt ttcggcgaga aatttgccgg
    36721 tttgtaccgc gtcggttatg tttcttccgt tatgctgggt accgtgttga gccttgattt
    36781 ggtgtggctg gcttcggaca cattcaacgg cttgatggca ttgcccaacc tgattgcact
    36841 tttattgatg gcgaaagtca tcgtcaatga aacgcgcgac ttcaaacaaa aaatcacaaa
    36901 tggcgaattg ccgcattaat atccgaggcc gtctgaatcc gaatattcag acggcacggc
    36961 atattaagtc tgttttgaaa aagccggagg gagaaacatg aaagtgcttg ttttaggtgc
    37021 gggtgttgcc ggcgtgtctt ccgcgtggta tctggcagag gcaggacatg aagtaacggt
    37081 catcgaccgc gccgagggtg tggcgatgga aaccagtttt gccaatgcag gccagctttc
    37141 ttacggctat accacgcctt gggctgcacc cggtattccg accaaagcac tgaaatggct
    37201 gtttaaaagc catccgcctt tgctgtttcg ccccgacggc agcctgtatc aaatcgaatg
    37261 gctgtggcaa atgctgcaaa actgcacggc agcgcactat caaaccaata aagagcgcat
    37321 ggtcaggatt tccgaatata gccgtgaaat gttccgccgt tttgaagcgc aaaccggcat
    37381 gaattttgag gaacgcaaaa aagggacgtt gcagattttc cgtcaggcta aagaagttga
    37441 agcggcagaa caagacattg ccgttttgga acgctacggc gtgccgtacc gccgtctgaa
    37501 acccgaagaa tgtgcagaat ttgagcctgc gctggcacgc gttaccgcca aaattgccgg
    37561 cggcctgcac ctgcctgcag atgcgaccgg cgactgccac ctcttcaccg aaaacctata
    37621 caaattgtgt caggaaaagg gcgtacagtt tcatttcaac caaaccatca gccgcatcga
    37681 ccataacggg ctgcgcatca aagccgttga aaccaaaaca gggcggtttg aagcagatgc
    37741 cgttgtctgt gcgctcggct gcttcagtag gactgtgttg gcgcagttag acctcgatct
    37801 gccgatttat cccgtcaaag gctattcctt gaccctgccg gtcaccaatt cagacggcgc
    37861 gccggtgtcc accgttttgg atgaaagcta caaagtcgct atcacgcgct ttgacaacag
    37921 aatccgcgtc ggcggcatgg cagaattgtc gggctacgaa atcaaactgc ccgaaaaacg
    37981 ccgcgaaacc ttggctttgg tcgtcaacga cttgttcccg gaaggcggcg atttgagcca
    38041 agcatcgttc tggagcggcc tcagaccgat gacgcccgac agcacgccgt taatcggtcg
    38101 cacccacttt gacaacctgt ttctgaatac cggccacggt actttaggct ggaccatgtc
    38161 gctgggttcg gcaaaattaa ccgccgatat cgtgagcggc aaagacaccg aaatccgcag
    38221 cgacgatttg agcctgtcgc tctatcaggc ttaagctgga aagcgataag gtttagtggc
    38281 atttcaaatg taaaggccgt ctgaaaacta tttttcagac ggccttttgt ttcaaaatcc
    38341 gtgtatccaa ccaataaaat aaataataac tattatcata cgcattaaaa agtgttagtc
    38401 tgaacctgtc ccagctttta gcgcaggttt tctcatgccc gatttttcga tgtccaattt
    38461 ggccgttgcc ttttccatca cgttggctgc cggtttgttt accgtattag gcagcggctt
    38521 ggtaatgttt tccaaaacgc ccaatccgcg tgtgttgtcg tttggtttgg catttgccgg
    38581 cggtgcaatg gtgtatgttt ccctgacgga gattttcagt aagtccagcg aggcgttcgc
    38641 tgaaatttat gataaagacc acgcgtttgc ggcggcgacc atggcatttt tggccgggat
    38701 gggcggcatt gcgctgattg accgtctggt gccgaacccg catgaaactt tagacgcgca
    38761 agacccgtcg tttcaagaaa gcaaacgccg ccatatcgcg cgagtcggca tgatggcggc
    38821 gtttgcgatt actgcgcaca atttccccga aggcttggcg acgttttttg ccacattgga
    38881 aaatccggcg gtcgggatgc ctttggcctt ggcgattgcc atccataata ttccggaggg
    38941 catttccatc gccgcgccgg tttattttgc cacccgcagc cgtaagaaaa cggtgtgggc
    39001 gtgtctgcta tccggcttgg ccgagccgtt gggggcggct ttgggctatt tggttttgca
    39061 gccgtttttg tcgcctgccg tgtttggttc ggtattcggc gtgatagccg gtgtgatggt
    39121 gtttttggcg ttggacgagc tgctgccggc cgccaaacgc tattcagacg gccatgaaac
    39181 cgtttacggc ctgacaacgg gtatggcggt gattgccgtc agcctggtat tgttccattt
    39241 ttaaaacccg tatgccaaag gccgtctgaa atgattcaga cggccttttt gcgttataat
    39301 ccgcacatca aaaataacct taatttcaca aagttccatc atgttagaca aatactcccc
    39361 cgccgaaatc gaatccaaac actatcaaaa ctgggaaagc caaggttatt tccagcccga
    39421 tatggatttg accaaaccgt ctttttccat ccaactgccg ccgcccaacg taaccggcac
    39481 gctgcacatg ggccatacct tcaaccaaac cattatggac ggtctgaccc gctactaccg
    39541 catgaaaggc tgcaacaccg cctggattcc cggcaccgac cacgcgggca tcgccacgca
    39601 aatcgtggtc gagcgtcagc ttgccgcgca aaacgtgtcc cgtcatgact tgggtcgtga
    39661 aaaattcttg gaaaaagtgt gggaatggaa agaagtttcc ggcggcacga ttacgcagca
    39721 gatgcgccgt gtgggctgtt ctgccgactg gacgcgcgag tatttcacaa tggacgatgt
    39781 acgcgccgaa accgtaaccg aagtgttcgt acgcctgtat gaacagggct tgatttatcg
    39841 cggcaaacgc ttggtgaact gggatccggt attgggtacc gcagtgtctg atttggaagt
    39901 ggaaagcgtg gaagaacaag gctctatgtg gcacatccgc tatccgctgg cggacaatcc
    39961 tgccgaagcc gtcatcgtcg ccaccacccg tcccgaaacg ctgttgggcg acgttgccgt
    40021 tgccgtcaat cccgaagacg aacgttatac ccacttaatc ggcaaagaat taatcctgcc
    40081 gctgaccggc cgcaccattc ccgtgattgc cgacgaatac gttgaaaaag acttcggcac
    40141 cggctgcgtg aaaatcacgc ctgcgcacga cttcaacgac tacgaagtcg gcaaacgcca
    40201 cgatacgcgc ttggttaatg tgttcgactt ggaagccaaa gtattggcaa acgccgaagt
    40261 gttcaacttc aaaggcgaag cgcaaccaag ctttgccctg cctgaaaaat acgcaggctt
    40321 ggaccgcttt gccgcgcgca aacaaatggt tgccgatttg caggaacaag gtttcttggt
    40381 cgaaatcaaa gcgcacacgc tgatgacgcc gaaaggcgac cgtaccggtt ccgtgattga
    40441 gccgatgctg accagccaat ggtttgtcgc catgtccgcc acgccaaacg gcggcgagcc
    40501 tgacagcgaa ttcaaaggct taagccttgc tgacaaagcc aaaaaagccg tcgacagcgg
    40561 cgcggtgcgc tttatccccg aaaactgggt caacacctac aaccaatgga tgaacaacat
    40621 ccaagactgg tgcatctcgc gccaactgtg gtgggggcat caaatccctg catggtacga
    40681 caacgaaggc aatgtgtacg ttgcccgcaa tcaggaagaa gccgaaaaac aagccggcaa
    40741 aacaggcttg acccgagaag aagacgtatt ggacacatgg ttctcctccg cactcgtgcc
    40801 gttctccacg ctcggctggc cgtctgaaac cgacgaactc aaagccttcc tgccgtccaa
    40861 cgtcttggtc accggctacg aaatcatctt cttctgggtg gcgcgcatga ttatgatgac
    40921 cacccacttt accggcaaag taccgtttaa agacgtgtac atccacggca tcgtgcgcga
    40981 ccacgaaggc aaaaaaatgt ccaaatccga aggcaacgtc attgaccctg tggatttgat
    41041 cgacggcatc gacttggaaa aactgctggt gaaacgtacc accggtctgc gcaaacccga
    41101 aaccgcgccg aaagtggaag aagccaccaa aaaactcttt cccgaaggca ttccgagtat
    41161 gggcgcggac gcattgcgtt tcaccatggc gagctacgcc agcttggggc gcagcgtgaa
    41221 cttcgacttc aaacgcgccg aaggctaccg caacttctgc aacaaaatct ggaacgccac
    41281 caacttcgtc ttgatgaaca ccgaaaacca agactgcggc tacggcgcaa ccgccaccga
    41341 accgcgcggc tattccttcc ccgatatgtg gattgtaggc cgtctgaatc agaccatcga
    41401 gcaggttacg caagcctacg aaacctaccg ctttgatttg gcggcggaaa ccctgtacag
    41461 cttcgtgtgg aacgactatt gcgactggta tttggaactt gccaaagtgc agcttcaaac
    41521 cggctgcgcc agccgccaac gcgccacacg ccatacctta ttgcgcgtac tcgaagccgc
    41581 cctgcgcctg ctgcacccga ttatcccgtt catcaccgaa gaactgtggc aaaccgtcgc
    41641 ccctatgtgc gacgcgaaaa ccgccgacag catcatgctc gcccgcttcc ccgaagccga
    41701 cggcggcgag attgttcaga cggcattcgg gcaaatgacc gtgttgcagg atttgatcgg
    41761 cgcagtccgc aacctgcgcg gcgaaatggg catccagccc aacgtgaaag ccccgctgtt
    41821 tgtcgaaagc gcagacgact tggcggacta cctcaaatac ctgccgatga tgacccgcct
    41881 gaccgaagca cagcaagtcg ccgccctacc cgaaagcgaa gacgcgcccg tcgccgtctg
    41941 caacggcgcg cgcctgatgt tgaaagtcga aatcgacaaa gctgccgaaa ccgcccgttt
    42001 gagcaaagaa gccgagaagc tgcaaaaagc cttggacaaa ctcaacgcca aactctccaa
    42061 acccggctac accgaaaaag ccccggcgca tttggtggaa aaagacaaag ccgatttggc
    42121 ggaattggaa gacaaaatgg caaaagtgca aactcagttg tcgaagttga aagactgatt
    42181 tgattgaatc aacaaggccg tctgaaaaat gtttttcaga cggcctcttt tatagtggat
    42241 taacaaaaat caggacaagg cgacgaagcc gcagacagta caaatagtac ggcaaggtga
    42301 ggcaacgccg tactggtttt tgttaatcca ctatacatgg cattgcatcg gcactgatga
    42361 aaacattcac agtgatgcaa aagtcgaata tcttcaggac ggcagtttcc gtggcgatgc
    42421 tatactcaaa atcgatgatg acggcaatat cttggcatac cgtgttgtcg gctcagggaa
    42481 atggcgtttt gaaaacaatg cctgcgccta gtcgcggata aaacttaccc cgtgaagctg
    42541 cgactgcata atcgccgcct tcatcgccga caacgccttc ggacggacaa aattgcggcg
    42601 gtacgccaat acgacccgcc ggcttggcgg cgtaccttca aacggaataa tgctgaacag
    42661 catatgatcg ttttcggtca gcgcggttgc cggtaacacg ctgattgcca aaccgctggc
    42721 gaccatatgg cggattgtat tgatcgagct gccctgcaat gtattggtca acccctgtat
    42781 gcgttgtttc gccgccaatt cggaacagct tgagagtacc tgatcccgca tacagttgcc
    42841 ttccgtcagc agcaaaacct gctcctcacc cagcatccgt ggcgaaacgg catccagttc
    42901 ctcaaatgaa tgccctttcg ggacaatcac gaaaaacggt tcgtcataca agggttcggt
    42961 aacaatgccc ggctcttgaa acggttcggc aacgataatc gcgtcaacgt ccccgcgttt
    43021 gagcgactcg gtcaaagtat gcgtgtaatt ctcttccaac atcaaaggca ttttcggtgc
    43081 agtacggcgc aacgagacaa tcagtttcgg cagcaggtac ggcgcaaccg taaaaatcag
    43141 cccgagtttg aacgcaccct ccagctcgtt ttgttcttca tttgccaaat gcctgataag
    43201 ctctgcctct tccaacacct tacgcgcctg tgcaacgata cgttcccccg cctcggtcgt
    43261 aataatatcg ttgctgctcc ggtcaaacaa agagacggca agctcttctt ccaatttctt
    43321 aatggcaata gacaaagtgg gctggctgac aaaacaacgc cgcgccgccc tgccgaaatg
    43381 acgttcttgg gcgactgcga cgatgtaccg caattcggtt aaggtcatgt cctatacctt
    43441 tttctgttcc ggcaaagtaa tgttcaactc aagcacatcc ataccatcct gtttttcctg
    43501 ggaaatacgg atattgtcta atgaaacatc cacatatttg gacaggactt ccatcaactc
    43561 tttacgtaaa gtcggcaggt aatccggagc ctgaccttct tgggcgcgct cttgggcaat
    43621 gatgatttga aggcggtcgc gggcaacggt tgccgttttc tgctttctgc cgaataaaag
    43681 ttcgattaat gacatacctc atcctccgaa cagacgtttg aagaagcttt ttttctcagc
    43741 ttccaagaaa cgcatttcac ggttctcgcc caaaagacgg gcaataacgt ccttatatgc
    43801 ctcggaagcc gccacgctgt cctgatggat gaccggttct ccggaattgg atgcctgcaa
    43861 gacgttttgg gattcgggaa tcacacccag caaaggaata tgcagaatat cgcaaatatc
    43921 ctgtacagac agcatttcgc cttttgccac acgttcggga gaataacgcg taatcaacag
    43981 atgttcttta accgaaccgc cttgctctgc cttatgggat ttgctttgca aaattcccaa
    44041 aatcctgtcg gagtcacgca cactggaaac ctcgggattg gtcgttacaa tggcttcatc
    44101 agcaaaatac aacgccatca atgcaccctg ctcaataccg gcaggagagt cgcaaataat
    44161 atactcaaag cccattttct tgccggacag ctcctgcatc actttttcta cgccctcgcg
    44221 tgtcaaagcg tctttatccc gagtctggga agccggcaaa ataaacaggt tttcacaatt
    44281 tttatcttta atcaaagcct ggttgagcgt cgcctccccc tgaatgacat tgatcaggtc
    44341 ataaacgaca cgacgctcgc aacccataat gaggtcgagg ttacgcaaac ccacatcaaa
    44401 atcaattacc gcagttttat atccgcgtaa tgccaaacct gtcgcaatac tggcactggt
    44461 agtcgtttta ccgacaccgc ccttacctga agttactaca ataatttttg ccacaatatt
    44521 tcctttttaa aatatcaaac aattactctg agccaattgc actgataacc aatcggttat
    44581 cctgcaacaa tatctgtacc ggctgcttgt gcagatggtc cggcaaatcc tgttcaaaat
    44641 tacggtaaat acccgccaca gaaaccagtt ctgcctgcat ggagtggata aatatgcggg
    44701 cagaagtatc acccttggcg ccggccaaag cacgccccct catcggcgca taaatatgta
    44761 tattgccatc cgcaatcaat tctgccccct ggctgaccgc ccccgtaaca atcaaatcgc
    44821 catcttcggc ataaacctgc tgaccggtac ggacagggga tgtaatcaat actgttttcc
    44881 ttgctttctg accatcctcc gttttctgca cctcaacctg acccagttct ttaacatttt
    44941 ccgaatgaga cagacaaaac agcaaatgat acttcatagc cgcagcagcc caacgttcat
    45001 cagaatgctt cagacccaaa atttgcatac catgccttga aaacaacgaa accaatgcag
    45061 caagatccaa agactcggga taatcaaact cttgaacatc cagaacaaat ggaacaacac
    45121 cagactcttg aaacttcttg cccaatttga ccagcacatc ttccaaatca aacaagtctg
    45181 atgtatgcaa agatatagac aatacgtcca tctttgtcga ctttatatcg aaggcattca
    45241 ttatataaac catcatagaa ttttttaatg atgtaagttt accgcgcaaa ccttagctat
    45301 tcaattaata ttttaaacat gatagccaat accctattac ctatcagata ttgcaaaaat
    45361 aacgccacct gcttttcggc agatggcgtt atatgactaa aattactcag cagccggttt
    45421 gtcaaccaat tcaaccagtg ccagaggtgc attatcacct ttacggaatc cgtatttcaa
    45481 cacccgaaca taaccaccgt tacgagcagt aaaacgagga cccaaatcgc caaacagttt
    45541 tactacaaca tcacggtcgc gagtacggtc aaatgccaaa cggcggtttg ccaatgacgg
    45601 ctttttaccc aatgtaatca acggctctac tacacggcgc aattccttgg ccttaggcag
    45661 agttgttaca atagtttcgt gagtcaataa tgaattcgcc atattacgca gcattgcagc
    45721 acgatgactg ctggtacggt ttaatttgcg attgccatta cgatgacgca tatcaattat
    45781 cctttaattc ttcattaagg cttttccaag cctacaggtg gccatgcttc caacttagaa
    45841 cccagtgtca aacctttaga tgccaatact tccttaatct cattcaaaga tttacgtccc
    45901 aaattcggcg ttttaagaag ctcggtttca gtgcgttgaa tcaaatcgcc aatataataa
    45961 atatcctcag ctttcaaaca attagctgaa cgtactgtca attccagatc atccaccgga
    46021 cgcaaaagaa cagggtcgat aggaggtgct ttttcttcaa cctcctccac aggcgtaccc
    46081 tgcaaatcag caaaaataga catctgatca atcaaaatac gtgccgcact gcgtacagct
    46141 tcctcaggat caatagaacc gtcggtttcg atatccaaaa ccaacttatc aagatccgtc
    46201 cgctgctcta cacgtgcagg ttcaacctca aagctaacac ggctgatggg cgaaaagctc
    46261 gcatccaact ggattgcacc aatctgacgg ttctcatcac gaactacctg acgacctgaa
    46321 acagattgat aaccacgacc ttgctctact ttaatttcca tctcaatttg accgttatca
    46381 gccaaatgac aaatgacatg accaggattc agaatttcta catcatgcgg caactcaata
    46441 tcaccggcag atacgacacc tgaacctgat ttcttcaaca caagttgaac ttggctacga
    46501 ccatggagtt taaacacaat acctttaata ttcagcaaaa tgtcaacaac atcttcctga
    46561 ataccatcaa cagtagaata ttcgtgtaat acaccggcaa tagctacttc agtaggagca
    46621 aaaccattca tggatgacag taagatacgg cgcaaagcat tacctaaggt atgaccgaaa
    46681 ccacgttcaa atggctgcat agatactttt gcacgagttg cagaaaaagt atttacatca
    46741 atttgacgag gtttcaaaaa ttcggttgtg ctattctgca tttaactgtc cctcactgag
    46801 ctagcattat ttagagtaga actctaccac cagctgttca ttaatatcac cggtcaattc
    46861 cgagcgatcc ggcatgtttt tgaacacacc ctcaagttta tccgcatcta cagaaaccca
    46921 acccggcaag ccgatttgag ttgccaaacc caatgcttct tgaatacgta cctgtttttt
    46981 ggctttttca cgaactgaga caacatcacc agctttcact tggaaagaag gaatattgac
    47041 aacttgtcca ttcacaacta tcgccttatg agaaacaagc tgtcttgctt cagctcgggt
    47101 agaaccgaaa cccatacgat aaacgacatt atccaaacga gattccagca actgcaacag
    47161 caactcgccg gtagaacctt tacgacgatc agcttctgcg aaataacgac ggaactgacg
    47221 ttctaatacg ccataaatac ggcggatttt ttgtttttca cgcaactgca aaccatagtc
    47281 tgacaaacgc ggtttttttg caccatgctg accgggagcg gaatcaattt tacatttaga
    47341 atccaaagag cggcgcgcac tcttcaaaaa caaatccgta ccttcgcgac gtgccaactt
    47401 acatttaggg ccaatataac gtgccatgtt tcaaatcact ccaatattaa atacgacgtt
    47461 ttttaggcgg acggcaaccg ttatgaggca acggggtaac gtcagtaatg ctggtaatct
    47521 tgaaaccaag agcattcaaa gcacgtacag aggattcacg acctggacct ggacctttaa
    47581 tacgaacctc taaattttta acgccatact cttgggcaac tttaccagct gcttctgctg
    47641 caacttgtgc tgcaaatggt gtacttttac gagaaccttt aaaaccagcg ccgccagagg
    47701 tagcccaaga caacgcattg ccttgacggt cagtgattgt aatgatggta ttgttgaaag
    47761 atgcatgaac gtgcacaata ccctcactca cggttttacg tactttttta cgtacacgtg
    47821 aagctgtgtt tgctttagcc attaataaaa ttccttaaaa tttatttctt accagcaatc
    47881 gctttacgcg gacctttgcg ggtacgcgca tttgtacgag tgcgttgacc gcggcatggt
    47941 aagccgcgac gatgacggaa gccacgatag cagcccatgt ccatcaatcg cttgatactc
    48001 atagttacct cacgacgcaa atcaccttct acttcatact tggcaacttg gtcacgcaaa
    48061 gcatctaatt gagtctcgtc caaatctttt gctttagtat caggcgcaat atttgcagcc
    48121 tcacaaatca atttagcacg agtagcacca ataccgtaaa tagcctgaag accaattacg
    48181 atgtgtgcgt tattagggat atttacccct gcaatacgag ccatattttt tcctttttag
    48241 ggcaaagtgt gtcactatat cacagaatca cattaaaaga aatattccat taaccttgac
    48301 gctgtttgtg acggagatca gtacaaatta cacgaactac acgatttcga cgaataatct
    48361 tgcaatttcg gcaaattttc ttaacagatg gttgtacacg cattttattt tccttttatt
    48421 ggtttatctt gctctgaaaa cgattcgagc cctagttaga tcataaggtg tcagctctac
    48481 tgtgacctta tctcccggag aaatacgaat gtaatgcatc cgcatcttcc cagaaatatg
    48541 acccaataca atatggtcat tctcaagttt tactttaaat gttgcattag gtaaagtttc
    48601 aagaatttca ccttgcattt ggatagtatc ttctttcgcc ataattctat ttccgagaaa
    48661 atgatttcat ttctgaacga gtcattaact tatcatactg ttgagtaagc ctatacgaat
    48721 ttatttgtgt actaaaatcc atcgttacaa caactagaat caacaaagac gtgccaccca
    48781 aataaaaagg tacatttaaa accgtagtta agaactctgg aattaaacaa atagttgtaa
    48841 tataaagagc tccaaacaat gtcaaacgta atacaacttt ttctaaatac ctagaggtct
    48901 gctcaccagg tctaatccca ggaacaaaag caccactctt ttttaaattc tctgccattt
    48961 ctttagggct aaaaaccaaa gccgtataaa aataacaaaa gaaaataact gtcgctgcaa
    49021 ataaagccat atacagcaat tgaccgtgtt gtaacaatcc agctattttg tgcaaaacac
    49081 tatttgtatc agccgaacca aaccaaccta aaagagtaga tggaaataga ataatactgg
    49141 aagcaaaaat tgggggaata acaccagcca tattcaactt gaaaggcata tgcgtatttt
    49201 gactacccgc cctaccatta aactggcgtt ttgcataatg aataggaatc ttccgctgtg
    49261 cactttcaaa gtatacaacc aaataaatta ataataaggc accaaataca ataaacaacg
    49321 ccgtaagcat gctcatagaa ccttggttcg tcagtgtaac cagctttgca atacccgaag
    49381 gaatacctga agcaatacct gccgtaatga ttaaagaaat accgttcccg ataccccttt
    49441 cagtaatttg ctccccaagc cacataagaa acatggttcc cgttaccaaa gaaactaccg
    49501 tggaaacatg aaactcaaat gaacttgtta caacaattcc ttgctgaaat acgaaagatg
    49561 caacacctag actttgaaga attgctaaca aaacagtacc atacctagta tatttcgtaa
    49621 ttacctttct accagcctcc ccttcttttt ttaaagcctt caatgatggc aaaatttcag
    49681 aagcgagctg tacaataata gaagctgaaa tatatggcat aattcctatt gcaaatatac
    49741 taaagcgctc taacgaccca ccggaaaaca tattcaatat tcccaggatg ccgtttccag
    49801 cgctttcgta taatttagct aaagcaacag catcaactcc aggtacaggt atatgggcac
    49861 caattcgaaa aacaatcaat gctccaaata gaaacaaaag acgtttctta agatctccaa
    49921 atttggatga acctgatgac gtttgttgat tagccacaat attaaacctt acatttcaat
    49981 cttaccacca acagcctcga tagcagctct cgcacctttg gtaactttaa tacccttcaa
    50041 agcaactgcc ttagaaattt caccagaagc aataacttta acattagaga ctgtagatgc
    50101 aatcagaccc gcttgcttta agaccaaaat atcaatctca ttaacagcaa ttgattccag
    50161 ttcacttaaa cgaagctgtg cattagctga tgctgttaaa gatttaaaac ctcttttagg
    50221 gaggcgtcgt tgcaagggca tttgaccacc ctcgaaaccc accttatgaa acccaccaga
    50281 ccggctcttt tgacctttat gaccacgacc acccgttttg ccaagaccac taccaatacc
    50341 gcgtccaaca cgacgaccag catgcgtagc accaacagca ggttgaattg tattcaaaaa
    50401 catatcaaga ctccactttc aacaagtagc tgattttatt aatcatacca cggttttcag
    50461 gggtatctaa aacctctacc gtatgctcgc gacgacgcaa acctaaaccg cgtgcacatg
    50521 cacgatgaga ttcaattgta ccaatcaggc ttttaaccaa tgtaacccta atcttttttt
    50581 gttcagccat ggttaactcc caaaatgtct tccactgtca agccacgttt ggctgcgata
    50641 tcagcaggag tatgcaactt agacaaacca tctaatgttg cacgtacgat attatatggg
    50701 ttagtagatc cgtgcacttt ggcggagata ttatgaatgc ccatagcatc aaaaaccaaa
    50761 cgcataggtc caccggcttt tacgccacta ccctctttag caggctgcat aaatacttta
    50821 gtagcaccat gtcgaccaat aacctcatga tgaatcgtac cattttttaa tggtacctta
    50881 atcatagagc gtcgtgcttg atccatcgcc ttttggactg caacaggcac ttcttttgac
    50941 ttacctttac ccataccaat acgaccatct ccatcaccaa caacagttag cgcagagaaa
    51001 gccataatgc gaccaccttt aactactttg gttacacggt taactgcgac catcttttca
    51061 atcagaccgt caccgcgttc ttcaatttca tgttttgcca tctgaaagtc tccaaatatt
    51121 tagaagctta aaccattttc acgagcagct tcagccaaag ccttcacacg accgtgatat
    51181 tggaaacctg aacgatcaaa agcaaccttt tctacacctg ctgctttagc cttctcagcg
    51241 atacgtttac caactattgc agctgcttca acattgcttc cagatttcag actaccgcgc
    51301 acctcagctt ccaatgtaga ggcttgagcc aatactttat caccttcagc actaattact
    51361 tgagcataaa tatgattatt gcttcggaac acacataatc ttaccatttt caagtccgca
    51421 atacgagcac gggttttgcg tgcacgacgg agtcgggttg tatgtttatc cattagtgaa
    51481 cctcaattat tttttcttgg cttctttcat taccactact tctcctacat agcgaacacc
    51541 tttaccttta taaggctcag gagcacggaa cgcacgaatc tcagcagcaa cttgaccaac
    51601 aacttgttta tccgagccgg ttaaaacaat ctctgtttgg ctaggagttt gaacggagac
    51661 accttcaggc atttcatata cgatcggatg agaaaaaccc aaagacagat tcaagatttt
    51721 accttgtgct tgagcacgat aacccacacc tatcaattgc aatcttttct caaaaccttc
    51781 tgaaacacct ttaaccatat tgctgactaa tgcgcgagca gtaccagaca ttgcatttgc
    51841 ttgtttactg ctgttattcg caacaaaagc caatttgcca tcattaaatt caatggctac
    51901 atcagaatgc aaaggaaaag acaattcacc gttcttaccc ttaataacta atgcctctgt
    51961 tccaaatttt acttctacac cagcgggaac agtcactggg ttttttgcga cacgtgacat
    52021 ttcttttcct ccactaggct acaatgcata acaactcacc accaacacct tgagaacgtg
    52081 ctttacgatc agtcattaca cctttagaag tactaacaat agcaataccc aagccattca
    52141 taacacttgg aatctcacta gacgctttat aaatacgcaa accggggcga gatacacgct
    52201 tgatttgttc aattacagga cgatctgcat agtattttaa ttgaatttcc aatatagact
    52261 ttacgtcaga tgaaactgcg aagtcctcaa tatatccttc ttctttcaat acctttgcaa
    52321 tagcacactt taattttgaa gaaggcattg caaccgctgc tttattagca cgttgcgcat
    52381 tgcggatacg agtcaacata tcggaaatag gatcatgcat actcattctt aattactcct
    52441 attaccagct ggctttaaca acacccggaa tttcgccacg catggcgatt tcacggattt
    52501 taatacgacc caaaccaaat ttacggaaag taccacgagg gcgacctgtc aaagcacaac
    52561 gacgacgttg acgcacaggt gccgcattac gaggaatgga ttgaaacctc aaacgagcct
    52621 caaaacgctc ttcctcagtt gcattcgaat cattgattac cgctttaatt gccgcgcgtt
    52681 tagccgcata ttttttagcc aaagcttgac gtttcagatt acgattaata agtgctttct
    52741 tagccatgat tatcctttga acggaaattt aaacaatgac aataaagctt tcgcttcctc
    52801 atcggttttt gctgtagtag taatagtaat attcaaacca cgcaaagcat caattttatc
    52861 gtattcaatt tccggaaaaa taatttgctc acgaacaccc atattgtaat tgccacggcc
    52921 atcaaatgat ttaccgctca caccacggaa gtcacgtacg cgaggtaatg caatagtaat
    52981 caaacgatcc aagaattcaa acatttgatc acgacgcaat gttactttgc aaccaaccgg
    53041 atagttatca cggattttaa aacctgcgat agatttacgg gcaacagtaa caaccggttt
    53101 ttgaccggca attttctcta aatcggaaac agcatgttcc ataacttttt tgtcagcaac
    53161 agcctcaccc acacccatat tcaaggtgat tttttcaata cgcgggactt ccattactga
    53221 tttgtaacca aattgtttaa ccaattcagg aacaactgtc tctttataaa actctctcaa
    53281 ccgagccatg ttatctcctt atgccccaat gatagagcca tttgatttga agaaacgaac
    53341 gcgtttaact ttgccttcat tttcaatcag cttaatacca acacggtccg ctttattagt
    53401 ttccggattc aggattgcga tattagaaat atccaaaggc atttctttag taataatacc
    53461 gccctcaatg ccacgcattg gattaggttt ttgatggcgt tttacaacat taacgccctc
    53521 aacaacaact ttatcaccca acactcgaac tacttgaccc tgcttacctt tatccttacc
    53581 agcaattact acaaccctat cgcctttaat gattttattc atcgtgccat tccttataat
    53641 acttcaggtg ccaatgaaac gattttcata aatcgctcag tacgcaattc acgggttacc
    53701 ggaccaaaga tacgagtacc caaaggttca agtttattat tcagtaacac ggcggcattg
    53761 ttatcgaatt taattaacgc accatcagga cgacgtacac ccttagcagt acgaacaact
    53821 accgcattat atacatcgcc ttttttgaca cggccacgcg gagccgcatc tttaactgcc
    53881 actttaataa tatcgccaac agaagcgtag cgacgcttag atccgcccaa taccttgata
    53941 cacattacgc gacgcgcacc agagttatca gccacatcta agatggtctg catttgaatc
    54001 atgttattac ctttaaatta accaacttaa tttaccactt tcagataact tacagcaaag
    54061 ccgctgctta ttaaatgaaa ccttgcggtt caagtaaacc agtcttggac cccgaaaggg
    54121 aagaaacttc cagaagaaac tgaaagacag gaaacgaagt ttacacgcaa attaaatttg
    54181 ctgcaatact tcgtttccca ttccaagcac gttgctttaa ttcttaaata gaacgtgctt
    54241 tctcaaccag ctcactgaca acccaagatt tagtttttga caatggacgg gattccgata
    54301 taacaaccac atcaccaatt ccatattgat tattttcatc atgggcatgg attttagtag
    54361 ataaccgaat aatcttacca tacagcggat gttttacttt acgctcaacc aatactgtta
    54421 cggttttatc cattttgtcg cttactactt tgccttgcaa agtacgaaca tttttagttt
    54481 cgctcattac ttagcacctt tttcagttaa aacggtttta atacgagcaa tatcgcgacg
    54541 tacacgtttc aattcacttg gtttgcctaa ttgaccggta gcgttttgca tacgtaagcc
    54601 aaactgagct ttcaacaagt ccaacaaatc tgcattcaac tgctcaacgg atttgtcttt
    54661 caattcattt gctttcatta ttgacccacc tgtcttacta caaaggttgt aggaataggc
    54721 aatttggcag cagccaactc gaatgcttca cgagccagtt cctctggaac gccatccatt
    54781 tcatacaaca ctttacctgg tttaatttcg gcaatgtaat attccacgtt acctttaccg
    54841 ccacccatac gaacttgaat aggcttttca gtaatcggtt tatcagggaa tacacgaatc
    54901 caaatacgac caccacgttt gatatgacgg gtcattgcac gacgagcagc ttcgatttga
    54961 cgggcagtca aacgaccacg acctacggct ttcaagccga actcaccgaa acttacctta
    55021 ttaccgcgag tagcgatgcc agtattgcga cccttttgtt gcttacggta tttcagtcta
    55081 gttggctgca gcattacgtc tacctgcctt tctttgttta ctctcatgtt caggtttgga
    55141 agatttaata ttgccttccg tataaaccca aactttcaga cccaatacac catatgtggt
    55201 gtgcgcttcg ctggttgcat aatctacatt tgcacgtaaa gtatgcagtg gcacacgacc
    55261 ttcacgatac cattcgctac gggcaatatc cgcaccattc agacggcctg aagtcataat
    55321 cttaatgcct ttagcaccag aacgcattgc attttgcatt gctcgtttca tagcacgacg
    55381 gaattgaacg cgcttttcca actgctgggc aataccgtca gcaataattt gagcatccaa
    55441 ctcaggacgg cgaatctctt caatatttac atgaacaggt acacccatca agacttgcaa
    55501 gtcacgtttc aaaacctcga tatcctcacc ttttttaccg ataaccacac ccggacgagc
    55561 ggagtgaatg gtaatgcgtg cagattttgc agggcgttca ataaccactc gaccaaccga
    55621 agcattggcc aatttttgac gcaaataatt gcgaacatcg atatcctgct tcaaaacagt
    55681 agaaaagtcg gtgcttttag caaaccattt tgaagcccag tctttagtta ccgccaggcg
    55741 aaagcctgta gggttaatct tttgtcccat agcttttcct tagttaccca ctgtcacatt
    55801 gatatgacaa gtttgttttt cgatgcggtt accgcgacct ttggcgcgag cttgaaaacg
    55861 tttcaagctt gggcctttgt caacaaagat agttaccact ttcagttcat caatgtccgc
    55921 accgttattg tgctcggcat tagcaatagc tgactccaat acttttttaa tcagctcggc
    55981 acctttttta ggactgaaag ccaaaatatt caaagcttgg gcaacgtctt taccacgaat
    56041 caaatcagct accaaacgag ccttttgagc agagatacgg gcatttttat gttgtgcatt
    56101 tactctcatg attcacctta tttcttttta gcctttttat cggccaagtg gcctttaaag
    56161 gtacgggtca atgagaattc gcctaattta tgaccaacca tattgtcgct gataaacaca
    56221 ggcacatggg tgcggccgtt gtgcacagca atggtcagac cgataaaatc aggcagaatg
    56281 gtagaacgac gagaccaggt tttaatcggg cgtttgtcgt tgcttgcgcg agcagcatct
    56341 acttttttca gcaaatgcag gtctacatat gggccttttt tcaatgaacg agccatacta
    56401 aattaacctt tatttgagta acggcgacga acaatcatgt tatccgtgcg tttgttatta
    56461 cgagtgcggt agcctttagc aggagtaccc catgggctga ccggttcgcg ggcctcgccc
    56521 gtacggcctt caccaccacc atgcgggtga tcgacaggat tcatgacaac accgcgtacg
    56581 gtcggacgaa taccgcgcca acggttggca ccggctttac cgattttttt caggctttgc
    56641 tcttcgttac caacttcacc gatggtcgca cggcaattta cgttgatttt acgaacttcg
    56701 ccagagcgca gacggacttg agcgtacgcg ccttctttag ccagcaatac cgcagaagca
    56761 ccggcagaac gtgcgatttg agcaccttta ccgggtttca tttcgataca gtggatagtc
    56821 gtaccaacgg gaatgttgcg gatcggcagg gtgttgccta ctttgatggc agcttcagca
    56881 ccggaaacca atacggcacc gacttgaata ccgcgaggag cgatgatgta acgacgctcg
    56941 ccgtctgcat agcacaacag tgcgatgaag gcagtacggt taggatcgta ttcgatacgc
    57001 tctaccttag caggaatgcc gtctttgtta cgtttaaagt ctacaacacg gtaatggtgt
    57061 ttatgaccgc cgcctttgtg acgggtggtg atatgaccat tactgttacg accggcagta
    57121 gaatttttct tttcgagcaa aggtgcataa ggcgcacctt tgtgcaaacc ttctgttacc
    57181 acgcgaacca tgccgcgacg gcctgcagag gtcggcttca ttttaacgat tgccattttg
    57241 tttattcctt atctgcagct gcagcagcgg cttccaaatc caactcttga ccggcagcca
    57301 agcttacata agctttttta acatcgctgc ggcggcccaa agtacgacca aaacgcttag
    57361 ttttgccttt agttgtaacg gtagttacag aagcaacttg aacaccaaac agcagctcaa
    57421 cagccgcttt gatttcaggt ttggttgcat ttgccaaaac tttaaacgtc atttggttgc
    57481 gtttttcagc caatacgttg cttttttcag aaacgatagg tgccaaaatc acttgagtca
    57541 aacgttgttg attcataccc attgctcctc taattgtgca actgcatctt tagtgatgat
    57601 tacttttttg taacgcagca agctgtaagg atcaacttgt tgagcttcca aaaccaacac
    57661 gtttggcaag ttgcgtgaag ccaagtaaac attctcgtcg agctgtttgg ttacaaacaa
    57721 cacttgctct agacccagat ttttcacttg ttcagcaaaa actttggttt taggagtttc
    57781 ggcagtcaac gcctcaatcg caaacaaacg ctcgtcacga gtcaattggg acagaatagt
    57841 cgccataccg gcacggtaca ttttgcggtt tactttttga gtgaagtttt cgtcgggttt
    57901 gttcgggaac gcgcgaccac ctttacgcca cagcggagaa gaagtcatac cggaacgggc
    57961 acggccggta cctttttgac gccatggttt tttggttgag tgttttactt cggcacgggt
    58021 tttttgagcg cggttaccgg agcgggcgtt tgccaagtag gcatttacca gctgatgaac
    58081 caacgcttca ttgtattcgc gggcgaacaa agcatcagaa acagacaggc tgcctgaaac
    58141 ttgtccttta gcgtcaatta ctttcaattc cattacgcac ctactttcac gctgggacga
    58201 actacaacat cgctgttgac cgcacccgga acagcaccct taaccaacag cagttggcgt
    58261 tctgcatcaa cacggacaac ttccaatttt tgaacagttg ccttggtgtt gccgtattgg
    58321 ccggccatgc gcttaccggg gaacacgcga cccgggtctt gtgccatacc gatagaacct
    58381 ggaacgcggt gagagcggga gttaccgtgg gaagtacgtt gggcgccgaa gttatgacgt
    58441 ttaatcgtgc cggagaaacc tttaccttta gaggtaccgg ttacatcgac cagttgaccg
    58501 acttcaaaca tagaaacggt gatttcgtca ccagctttca attcagccag tttttcttca
    58561 gtcaaagcaa actcaatcaa accgcgaccg gcttcaacac ctgcttttgc aaagtgcccg
    58621 gcttcggctt tgttgacacg attggctttt ttctgaccaa aggtaacttg aacggcagta
    58681 tagccgtcag tatctttgga ttttacttgt gtaacgcggt tggcagacat atccaaaacg
    58741 gttaccggaa cagaaacacc ctgttcgtcg aacacgcggg tcataccaac tttgcgtcca
    58801 accagaccta aagtcatgat tattttcctt ttaaagtaaa gggacaggct acgattggcc
    58861 tgtctttcag acaaagttaa acttggcaca aatgtaccaa gctcggcatt atatctgaca
    58921 agttaaagaa atatcaacag aaatatcaga aatatcttca atatgccgtc tgaagcgttt
    58981 tgaattttca gacggcatag ggtcagactc ttttaaaggg tcggtatccg gtcatcacag
    59041 cgtatgcatc tttctccgac aaaccggaat atggttgatg actgtaatcg gggatgctca
    59101 gttcgtcaaa gcggcaaaac aggttgaaat cgatgcgggt gatgaggctg tg
//
LOCUS       DAXISH010000006        54877 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.006, whole genome shotgun sequence.
ACCESSION   DAXISH010000006 DAXISH010000000
VERSION     DAXISH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 54877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54877
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.006"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..211
                     /locus_tag="ACFOV4_000363"
     CDS             <1..211
                     /locus_tag="ACFOV4_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618451.1"
                     /translation="DFLIWRPAHHFRPIETPVLKDCVYFHRRFKGRRYSADGAQTAFR
                     RHFHSFGVSVRIALPVRAISPCGLP"
     gene            complement(286..1749)
                     /gene="guaB"
                     /locus_tag="ACFOV4_000364"
     CDS             complement(286..1749)
                     /gene="guaB"
                     /locus_tag="ACFOV4_000364"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003767939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFC7618452.1"
                     /translation="MRIVEKAYTFDDVLLVPAHSTVLPRDVKLQTKLTREITLNLPLL
                     SAAMDTVTEARLAISMAQEGGIGIIHKNMPPEMQARAVSKVKRHESGVVKDPVTVAPT
                     TLIREVLEMRAQRKRKMSGLPVVENGKVVGIVTNRDLRFENRVDLPVSAIMTPRERLV
                     TVPEGTSIDEARELMHTHKVERVLVLNEKDELKGLITVKDILKTTEFPNANKDSEGRL
                     RVGAAVGTGGDTEERVKALVEAGVDVIVVDTAHGHSQGVIDRVKWVKETYPHIQVIGG
                     NIATAKAALDLVAAGADAVKVGIGPGSICTTRIVAGVGVPQLTAIHNVAEALKGTGVP
                     LIADGGIRFSGDIAKALAAGAYSVMLGGMFAGTEEAPGEIELYQGRSYKSYRGMGSLG
                     AMSQGSADRYFQDKTDSTDKYVPEGIEGRVPYKGPIVNIIHQLTGGLRSSMGYLGCAN
                     IAEMHEKAEFVEITSAGMSESHVHDVQITKEAPNYHR"
     gene            complement(1890..4448)
                     /gene="glnD"
                     /locus_tag="ACFOV4_000365"
     CDS             complement(1890..4448)
                     /gene="glnD"
                     /locus_tag="ACFOV4_000365"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0018177 - protein uridylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[protein-PII] uridylyltransferase"
                     /protein_id="HFC7618453.1"
                     /translation="MPANLSSALETFKQQRDAAEAHYLKANRVSVFFREYTAALETLL
                     AALWAEYFQNSALCLMAVGGFGRGELYPCSDVDLAVVSPAPLSDGIQEQIARFVQTLW
                     DCKLMPSVKSGSVDELCESVRNDITGDTAFLEARFLFGNRQTADKLAEKMNAQRNVAA
                     FVEAKLVEMEHRHAKSQGSGAVLEPNIKSCPGGLRDIHTLLWIAKAQGLATDLPDLLK
                     QRILTCAEAGMLSHGYRRLAHIRIHLHLNAKRAEDRLLFDLQPQVAESMGYEGLNLRR
                     QSEELMRVFYRAIKTVKQLGGILTPMLQSRVSSTPLRVTLRIDDDYIQVNNQIAARHT
                     DIFFRRPEHIFKIVEIMQQRNDITALEPQTLRAWWGATRKINRSFYQNSENRHRFAGF
                     FRNGNGLTQTLRFLNLYGVLGRYLPAWEKIVGLLQHDLFHIYPVDDHILAVVRNVRRL
                     ALDMHSHELPYASALMQSFEKQDILYLAAFFHDIAKGRGGDHAIQGISDARQFAADHF
                     LTEEESDLLAWLVENHLLMSIVAQKEDIQDPDVLDAFCKRVQTHERLSALYLLTISDI
                     RGTNPKLWNAWRASLLESLFHAAGRYLAGNGGNPHALFGRRQQEAADLLTRAAVPEKQ
                     QKKLWNALGSAYFARHQSREILWHAANLVHDFETPIVRSRILPKSDSFQVMVFMPNGP
                     RLFARLCRIFSRHGFDILAARAFITEHDYILDTFIVQIPSQHAPEDYPDIQSALEAEL
                     NSFIHGHTVAETSNHSRRISRRSRYMPIAPSITITPEEDYPDWYSVEITAVNRPFLLA
                     DMAEIFFAHNVSLRYAKISTLDERAEDSFTVFSPDLKNPKIQSSLKQTLLEQLS"
     gene            complement(4497..4817)
                     /locus_tag="ACFOV4_000366"
     CDS             complement(4497..4817)
                     /locus_tag="ACFOV4_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC7618454.1"
                     /translation="MMGNKLTLPAELPDEQDLRAVLAYNMRLFRVNKGWSQEELARQC
                     GLDRTYVSAVERKRWNIALSNIEKMAAALGVAAYQLLLPPQERLKLMTNSADTRQMPS
                     ESGI"
     gene            complement(5141..5614)
                     /gene="bfr"
                     /locus_tag="ACFOV4_000367"
     CDS             complement(5141..5614)
                     /gene="bfr"
                     /locus_tag="ACFOV4_000367"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HFC7618455.1"
                     /translation="MKGDRLVIRELNKNLGLLLVTINQYFLHARILKNWGFEELGEHF
                     FKQSIVEMKAADDLIERILFLEGLPNLQELGKLLIGESTEEIIACDLTKEQEKHEALL
                     AAIATAEAQQDYVSRDLLEKQKDTNEEHIDWLETQQELIGKIGLPNYLQTAAQED"
     gene            complement(5642..6106)
                     /gene="bfr"
                     /locus_tag="ACFOV4_000368"
     CDS             complement(5642..6106)
                     /gene="bfr"
                     /locus_tag="ACFOV4_000368"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HFC7618456.1"
                     /translation="MQGNQAVVDYMNELLSGELAARDQYFIHSRLYSEWGYTKLFERL
                     NHEMEEETTHAEDFIRRILMLGGTPKMARAELNIGTDVVSCLKADLQTEYEVRDALKK
                     GIKLCEEAQDYVSRDLMVAQLKDTEEDHAHWLEQQLRLIELIGEGNYYQSQL"
     gene            complement(6570..7553)
                     /gene="lipA"
                     /locus_tag="ACFOV4_000369"
     CDS             complement(6570..7553)
                     /gene="lipA"
                     /locus_tag="ACFOV4_000369"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016992 - lipoate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HFC7618457.1"
                     /translation="MSEIKTDDPKRGIKLRGADKTARIPIKVVPLQEKLKKPEWIRAK
                     LPSRKFFEIKDILREQKMHTVCEEASCPNIGECFSKGTATFMIMGDICTRRCPFCDVG
                     HGRPNMLDPDEPRNLAESVKAMNLRYVVITSVDRDDLRDGGAQHFADCIKAIRETSPN
                     TKIEILVPDFRGRLDIALKILAETPPDVMNHNLETHPSLYRKARPGANYQHSLDLLKR
                     YKEMMPHIPTKSGIMVGLGETDEDVREIMRDMRAHNIEMITIGQYLQPSDGHLPVLRY
                     VTPEQFKIFEKEAYELGFSNAAIGAMVRSSYHADEQAAEALRESHGGCGHH"
     gene            complement(7546..8169)
                     /gene="lipB"
                     /locus_tag="ACFOV4_000370"
     CDS             complement(7546..8169)
                     /gene="lipB"
                     /locus_tag="ACFOV4_000370"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HFC7618458.1"
                     /translation="MKVIHKGLVEYLPTFEAMKTFNAGRNADTEDELWVVEHPPVFTQ
                     GLAGKPEHLLIRDDIPVVQIDRGGQITYHGPGQLVVYTMIDFKRRKTSVRNIVSALEN
                     SIIATLAEYGIEAAADPKRPGVYVGERKIASLGLRIKNGSVYHGLALNVNMDLSPFTH
                     INPCGYAGMEMTQIADFVQPCPTPDEVAAKLTAHLETQFTPKADNNE"
     gene            complement(8171..8446)
                     /locus_tag="ACFOV4_000371"
     CDS             complement(8171..8446)
                     /locus_tag="ACFOV4_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HFC7618459.1"
                     /translation="MTEQKNKTSLIEFPCTFSLKVMGAVHPEFEQAVLDTVRLHAPDT
                     QAHHITTRPSSKGNYTGATVQIKVENQEQLDNIYRALTSHELVKVVL"
     gene            8631..9701
                     /locus_tag="ACFOV4_000372"
     CDS             8631..9701
                     /locus_tag="ACFOV4_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFC7618460.1"
                     /translation="MYRRKGRGIKPWMGAGAAFAALVWLAFALGDTLAPFAVAAVLAY
                     VLDPLVEWLQKKGLNRASASMSVMVFSLILLLALLLIIVPMLVGQFNNLASRLPQLIG
                     FMQNTLLPWLKNTIGGYVEIDQASIIAWLQAHTGELSNTLKAWFPVLMRQGSNIVSSI
                     GNLLLLPLLLYYFLLDWQRWSCGIAKLVPRRFAGAYTRITGNLNEVLGEFLRGQLLVM
                     LIMGLVYGLGLVLVGLDSGFAIGMVAGILVFVPYLGAFTGLLLATVAALLQFGSWNGI
                     LSVWAVFAVGQFLESFFITPKIVGDRIGLSPFWVIFSLMAFGQLMGFVGMLAGLPLAA
                     VTLVLLREGVQKYFAGSFYRGR"
     gene            complement(9898..10845)
                     /locus_tag="ACFOV4_000373"
     CDS             complement(9898..10845)
                     /locus_tag="ACFOV4_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stomatin-like protein"
                     /protein_id="HFC7618461.1"
                     /translation="MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGL
                     NILIPFIDRVAYRHSLKEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSN
                     YIMAITQLAQTTLRSVIGRMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKD
                     LVPPQEILRSMQAQITAEREKRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAV
                     NASNAEKIARINRAKGEAESLRLVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVA
                     AFNNLAKESNTLIMPANVADIGSLISAGMKIIDSSKTAK"
     gene            complement(10860..11267)
                     /locus_tag="ACFOV4_000374"
     CDS             complement(10860..11267)
                     /locus_tag="ACFOV4_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFC7618462.1"
                     /translation="MTVWFVAAVAVLIIELLTGTVYLLVVSAALAGSGIAYGLTSSTP
                     AAVLTAALLSALGIWFVHAKTAVRKVETDSYQDLDAGQYVEILRHTGGNRYEVFYRGT
                     HWQAQNTGQEELEPGTRALIVRKEGNLLIIAKP"
     gene            11348..12007
                     /gene="ung"
                     /locus_tag="ACFOV4_000375"
     CDS             11348..12007
                     /gene="ung"
                     /locus_tag="ACFOV4_000375"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFC7618463.1"
                     /translation="MDTWHDALGGEKQQPYFQEILNAVRQERLSGQIIYPPAADVFNA
                     FRLTAFDRVKAVILGQDPYHGAGQAHGLAFSVRQGIRIPPSLLNIYKELETDIEGFSI
                     PAHGCLTAWAEQGVLLLNTVLTVRAGQAHSHALLGWERFTDTVIRQLATHRKHLVFML
                     WGGYAQQKRKLIDSQNHLILTAPHPSPLSAYRGFFGCRHFSQANSYLSRHGIDPINWK
                     L"
     gene            complement(12114..12470)
                     /locus_tag="ACFOV4_000376"
     CDS             complement(12114..12470)
                     /locus_tag="ACFOV4_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618464.1"
                     /translation="MMKKQRHILCVGCLYIILKVNVFPNTGWMEASKGMQGISFSTFG
                     YADAPGYTFSRIVHTLIFLLGKTTGTRTTVSDSSHNVYYVKLLPKPSTKRLCRICRQA
                     NKSCFWKWRQKMPSEP"
     gene            complement(12515..13030)
                     /locus_tag="ACFOV4_000377"
     CDS             complement(12515..13030)
                     /locus_tag="ACFOV4_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618465.1"
                     /translation="MKSKLPLILINFSLISSPLGANAAKIYTCTINGETVYTTKPSKS
                     CLSTDLPPIGNYSSERYIPPQTSEPTPSPSNGGQAVKYKAPVKTVSKPAKSNTPPPQQ
                     APVNNSRRSILEAELSNERKALTEAQKMLSQARLAKGGNINHQEINALQSNVLDRQQN
                     IQALQRELGRM"
     gene            complement(13496..15299)
                     /locus_tag="ACFOV4_000378"
                     /pseudo
     CDS             complement(13496..15299)
                     /locus_tag="ACFOV4_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706256.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(15376..15747)
                     /locus_tag="ACFOV4_000379"
     CDS             complement(15376..15747)
                     /locus_tag="ACFOV4_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mth938-like domain-containing protein"
                     /protein_id="HFC7618466.1"
                     /translation="MLFEENPIDGQFAEYECGAGGIRLAGQSFHKPVLVHKDSVCLSQ
                     CRTLSDLTPENLLSDIKPVDYPEILIIGTGAAQEFIHPKIMADFSRIGISVECMNTDS
                     AFRTLVFLHSEGRRAWAWLQP"
     gene            15944..17251
                     /locus_tag="ACFOV4_000380"
     CDS             15944..17251
                     /locus_tag="ACFOV4_000380"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HFC7618467.1"
                     /translation="MKPVNIGLLGLGTVGGGTAAVLRDNAEEISRRLGREIRISAVCD
                     LSEEKARQICPSAAFVKDPFELVARKDVDVVVELFGGTGIAKDAVLKAIENGKHIVTA
                     NKKLLAEYGNEIFPLAEEKNVMVQFEAAVAGGIPIIKALREGLAANRIKSIAGIINGT
                     SNFILSEMREKGSAFADVLKEAQALGYAEADPTFDIEGHDAGHKITIMSALAFGTPMN
                     FSACYLEGISKLDSRDIKYAEELGYRIKLLGITRKTGKGIELRVHPTLIPESRLLANV
                     NGVMNAVRVNADMVGETLYYGAGAGALPTASAVVADIIDIARLVEADTAHRVPHLAFQ
                     PAQVQAQTILPMDEITSSYYLRVQAKDEPGTLGQIAALLAQENVSIEALIQKGVIDQT
                     TAEIVILTHSTVEKHIKSAIAAIEALDCVEKPITMIRMESLHD"
     gene            17244..17678
                     /locus_tag="ACFOV4_000381"
     CDS             17244..17678
                     /locus_tag="ACFOV4_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618468.1"
                     /translation="MTEPKHEMPTEEQVAARKKAKAKIRTIRIWAWVILALLASTALL
                     SQCAMSKPQAKQKIVESCVKNIPFAEKWQNDLRARGLDSNNTRLTVDYCKCMWEQPLD
                     RLSEKQIRSFGKLGAQEQLDLLGGANAFEARDKQCVADLKSE"
     gene            complement(17737..18006)
                     /locus_tag="ACFOV4_000382"
     CDS             complement(17737..18006)
                     /locus_tag="ACFOV4_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007342959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFC7618469.1"
                     /translation="MNKSELIEAIAQEADISKAAAQKALDATTNAVTTALKQGDTVTL
                     VGFGTFYVGERAERQGRNPKTGEPLTIAAAKTPKFRAGKALKDAL"
     gene            complement(18188..20650)
                     /gene="lon"
                     /locus_tag="ACFOV4_000383"
     CDS             complement(18188..20650)
                     /gene="lon"
                     /locus_tag="ACFOV4_000383"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HFC7618470.1"
                     /translation="MTQKEKHFEEYAALATLPLRDVVVYPHMVLPLFVGRPKSIAALE
                     NAITREEPVFLLAQTDAALEEPVAADLYQTGTVAQVLQVLKLPDGTVKVLVEGLYRGR
                     VLTIEDTGGLFVSHIEAVVEEDTGGNTDLEAVRRTLLAQFEQYAKLNKKIPAEIIGSI
                     NGIAENSRLTDTVAAHLQLKLAQRQQILEIPEIGKRMEFLLAQLESELDIMQAEKRIR
                     GRVKRQMEKSQREYYLNEQIKAIHKELGEEDENGELDALEAGIKKAGMSKEAEEKCLS
                     ELKKLKMMPPMSAESTVVRNYIDTLLELPWKKKSRVSKDIAKAGLVLDADHYGLEKVK
                     ERILEYLAVQKRMDKLKGPILCLVGPPGVGKTSLGESIAKATGRKYVRMALGGVRDEN
                     EIRGHRRTYIGSMPGKILQNMAKAGVKNPLFLLDEIDKLGSDFRGDPASALLEVLDPE
                     QNNKFADHYAEVDYDLSDVMFIATSNSLNIPTPLLDRMEIIRLSGYTEDEKINIAMQY
                     LVPKQMKRNGVKEGELAIEESAVRDIIRYYTREAGVRSLDREIAKICRKVVMQITLDE
                     DKKRLSETKKTSKAKPKAVKVNEKNLHDYLGVRRFDYGVAESENRIGQVTGLAWTEVG
                     GELLTVEAAALPGKGVIQCTGQLGDVMKESVSAAWSVVRSRAESVGLAPDFYEKKDIH
                     VHVPEGATPKDGPSAGIAMTLAMVSAFTKIPVRADVAMTGEITLRGEVLPIGGLKEKL
                     LAALRGGIKHVLIPKDNLKDLEEIPENVKTGLTIHPVKWIDEVLALGLESQPEPWAEP
                     SGAEAAAESASKPKPRSRATKH"
     gene            20901..22004
                     /locus_tag="ACFOV4_000384"
     CDS             20901..22004
                     /locus_tag="ACFOV4_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HFC7618471.1"
                     /translation="MSSFIFPDNGAEWRNESVQKPPKGWHYVRESGADGILKAAYQNI
                     ATVWQGDFHNAKQVLSAMKKRARKPAAVRSDADIAALFHAHRMKQAQQSRILNMLAVE
                     IRPGFVLDNKRAPDIRAALLDVYGEADGKPFFLPLNLLLGFMGAHEWHKKGVAVPQLG
                     GSIHVPFGVFSPLRGEYLDLLAHAPSTGFQTAFDIGTGSGVLAAILAKQGIPSVIGTD
                     TNPKAVACARANIARLGFEKQVEIRETDLFPEGFADLIVCNPPWLPAKPTSAVESALY
                     DPESAMLAAFLRDAPKHLNPDGEIRLIISDLAEHLHLRPSDFLDKAFAQAGLRVADVL
                     KTKPVHKKAADPNNPLAFARNRETTFLYRLKKA"
     gene            complement(22076..23821)
                     /gene="recD"
                     /locus_tag="ACFOV4_000385"
     CDS             complement(22076..23821)
                     /gene="recD"
                     /locus_tag="ACFOV4_000385"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HFC7618472.1"
                     /translation="MERQTDEFAQAAARAAIRFLEHYAGSGDEVLANCTERLFQALQN
                     GHSFIRLSGGEADALSALAPVVGTSAAPLILEGRRLFLGRMWQLEYDLAAEIKRLAAA
                     DTSAPDAAGARQNLAKWFQGTGSEGQRDAAALALLQSFMVITGGPGTGKTTTVAKLLA
                     LICGEDENLPNIALAAPTGKAAAHMARALHRAINGFDAPEAVRRHLLKLEGQTVHRLL
                     KLRPPKMQAAFNPVYPLPFDVLVIDEASMLDTALMLQLLKAVKTGARVILLGDENQLP
                     SVGIGAVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPVLAQNTAHLSFSHRFGD
                     NSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGN
                     IEAAYAGISDIVVLAAWRQDAEDFNEAYCRHVRRKMNIPEHLAYFAGEPIMIRQNDYA
                     LELFNGDIGLIMEDVGRQGSLAAYFADADGFKKVAVSCLPEFEPAFAMTVHKSQGSEY
                     REVWLLPPSAAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGEEAFRQAAATVKTR
                     QTALGSMLERVFSQE"
     gene            complement(23889..24584)
                     /gene="lolD"
                     /locus_tag="ACFOV4_000386"
     CDS             complement(23889..24584)
                     /gene="lolD"
                     /locus_tag="ACFOV4_000386"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HFC7618473.1"
                     /translation="MSELILKCEGVGKRYRDGGLDVLVLHGLDLEIRAGESTGIIGSS
                     GSGKSTLLHILGGLDMPSEGRVLLMGEDLRTLSQRQLGILRNHHLGFVYQFHHLLPEF
                     SALENVMMPLLIGKKSREEAAEAAMAMLEKVGLKHRSTHRAGELSGGERQRAAIARAL
                     VTQPKCLLADEPTGNLDRANARNVLDMMLELKTELGTGLVVVTHDDELAGRFERVMVM
                     KDGSLHPKQGANA"
     gene            complement(24577..25824)
                     /locus_tag="ACFOV4_000387"
     CDS             complement(24577..25824)
                     /locus_tag="ACFOV4_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit"
                     /protein_id="HFC7618474.1"
                     /translation="MFSLEAWIGLRYLRAKKRNGFMSFITMVSIAGIALGVTALIVVL
                     SVMNGFQKEIRGQLLNVAPHAEIGYIDNTDTDWRNLLRFTENRKGILAAAPYVSNQAL
                     LANAGEIRGVQMRGILPSEERKVVEYGDKMPAGKFEDLIPGEFDIILGVGLAEALGAE
                     VGNKVTVITPEGNVTPAGVVPRLKQFTVVGLVKTGVYEVDNSLAMTHIQDARVLYRLD
                     KEVAGLRLKLADPQNAPALTATLIPEAQRDTVWVRDWTFSNRSYFEAVELEKRMMFII
                     LTLIIAVAAFNLVSSLVMAVTEKQADIAILRTLGLSPGGVMKIFMVQGAFSGFFGTLA
                     GVVCGVLLGWNVGRVVAFFENLLGVHLINSQVYFIDYLPSDVDMGDVALIACISLGLS
                     FVATLYPSRRASKTQPAEALRYE"
     gene            26029..26307
                     /locus_tag="ACFOV4_000388"
     CDS             26029..26307
                     /locus_tag="ACFOV4_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618475.1"
                     /translation="MNIRTAFALCAIALSAAAAAYAKEIKIDANNTPYSEADAQKLAV
                     TAVGMGVKEPISLNGGSDSITVSGSSATQCVFKVGNGGALQIQGLNCK"
     gene            complement(26363..26980)
                     /gene="recR"
                     /locus_tag="ACFOV4_000389"
     CDS             complement(26363..26980)
                     /gene="recR"
                     /locus_tag="ACFOV4_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFC7618476.1"
                     /translation="MSHKKQDAFQGLIDALKVLPNVGPKSAQRIAYHLLQHKRKEAEK
                     LVDALQTALKQVYHCAMCNTFCEGGLCDICADETRDGRRLMVVHMPADVSNMEAANCH
                     DGLYFVLMGQINTALGMDVSAIALDRLAQRLGGGEVEEIIIATAFTAEGNATAYVLSE
                     FFKNLPYKVSRLSQGIPLGGELEYVDAGTLAQAVYERRLIKEGGA"
     gene            complement(27047..28585)
                     /locus_tag="ACFOV4_000390"
     CDS             complement(27047..28585)
                     /locus_tag="ACFOV4_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SurA N-terminal domain-containing protein"
                     /protein_id="HFC7618477.1"
                     /translation="MFHSIEKYRTPAQVLLGLIALTFVGFGVSTVSHPGADYIVQVGD
                     EKISDHSINNAIQNEQADGGGPSRDAVFQSLLQRAYLKQGAKLMGISVSSEQIKQIIV
                     DDPNFHDANGKFDHALLNRYLSQRHMSEDQFVEEIRDQFALQNLVNLVQNGVLVGDAQ
                     AEQLIRLTQVNRTIRSHTFNPDEFIAQVKVSEADLQKFYNANKKDYLLPKAVKLEYVA
                     LNLKDFADKQTVSETEVKNAFEERVARLPANEAKPSFEQEKAAVENELKMKKAVADFN
                     KAKEKLGDDAFNHPSSLAEAAKNSGLKVETQETWLSRQDAQMSGMPENLINAVFSDDV
                     LKKKHNSEVLTINSETAWVVRAKEVREEKTLPFAEAKDAVRQAYIRTEAAKLAENKAK
                     DVLTQLNGGKAVDVKWSEVSVLGAQQARQSMPPEAYAELLKVKPANGKPAYVRLTGLP
                     APVIVEVQAVTPPDDAAARIPLAKQALAQQQSANTFDLLIRYFNGKIKQTKGAQSVDN
                     GDGQ"
     gene            complement(28645..29019)
                     /locus_tag="ACFOV4_000391"
     CDS             complement(28645..29019)
                     /locus_tag="ACFOV4_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HFC7618478.1"
                     /translation="MIVLHGIPNCDTVKKAKNRLAGYGLEFEFRDFKKQVPSEAEICS
                     WLEQVPLATLLNKRGTSWRKLDAETQQKALFSTAEAVKLMSEMPSLIKRPVLECGGKV
                     YAGFSEETYDGIFNRQAPCRQG"
     gene            29169..30797
                     /locus_tag="ACFOV4_000392"
     CDS             29169..30797
                     /locus_tag="ACFOV4_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HFC7618479.1"
                     /translation="MISTNGITMQFGAKPLFENVSVKFGEGNRYGLIGANGSGKSTFM
                     KILGGDLEQTAGEVAIENGVRLGKLRQDQFAYEDMRVLDVVMMGHTEMWAAMTERDAI
                     YANPEATEDDYMKAAELEAKFAEYDGYTAEARAAELLSGVGISEDLHNAKMAEVAPGF
                     KLRVLLAQALFSKPDVLLLDEPTNNLDINTIRWLEGVLNQYDSTMIIISHDRHFLNEV
                     CTHMADLDYNTITIYPGNYDDYMLASAQSRERALKDNAKAKEKLQELQEFVARFSANK
                     SKARQATSRLKQADKIKSEMVEVKPSTRQNPYIRFEADEKAKLHRQAVEVEKLAKRFE
                     TQLFKNLNFILEAGQRLAIIGPNGAGKSTLLKLLAGAYNPEYSDGLLPDEGTIKWAEK
                     ASVGYYPQDHENDFDVDMDLSEWMRQWGQEGDDEQVIRGTLGRLLFGSNDVVKKVKVL
                     SGGEKGRMLYGKLLLLKPNVLVMDEPTNHMDMESIESLNMALEKYNGTLIFVSHDRQF
                     VSSLATQIIELDGKGGYEHYLGDYESYLEKKGVA"
     gene            30869..32122
                     /locus_tag="ACFOV4_000393"
     CDS             30869..32122
                     /locus_tag="ACFOV4_000393"
                     /EC_number="2.7.7.72"
                     /EC_number="3.1.3.-"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004810 - CCA tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional CCA addition/repair protein"
                     /protein_id="HFC7618480.1"
                     /translation="MQTYLVGGAVRDYLLGLPVKDRDWVVVGADAQTMLAQGFQPVGK
                     DFPVFLHPETHEEYALARTERKTAKGYVGFSFHADKDVTLEQDLMRRDLTINAMAQDA
                     DGKIIDPFGGQRDLAAGILRHVSPAFAEDPVRILRTARFAARYRFEIAEETIKLMRQM
                     VENGEADALVAERVWQEFAKGLMEKNPRKMIEVLRECGALKVLLPEVNALFGVPQRAD
                     YHPEIDSGIHTLMTLQRAADMGLSLPERYAALLHDLGKAKTPSDILPRHHGHDLAGVE
                     PVREVNQRLRAPKHCAELAELVCRWHIIFHQVEKLRSKTIIDVLKKTDAFRRPERFQT
                     ALNVCIADTQGRLNREHTPYPQRAHWLALLEAANQADSGKIAAECRAQGKAHLIAEQI
                     DRARLAQIAPLQKAFRAAQDKTEKH"
     gene            32345..32653
                     /locus_tag="ACFOV4_000394"
     CDS             32345..32653
                     /locus_tag="ACFOV4_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618481.1"
                     /translation="MTLKTDLLPKINNEDYQRLILKHSAEFSGGEIRLLNEILEKFNF
                     DVVQAQALAQAVMQQIRFDPNAYHIDSDDEDTTGICPHCINPPMPPLRDYLVWRETRG
                     "
     gene            32735..33766
                     /gene="ruvB"
                     /locus_tag="ACFOV4_000395"
     CDS             32735..33766
                     /gene="ruvB"
                     /locus_tag="ACFOV4_000395"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFC7618482.1"
                     /translation="MLQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQD
                     KAKEQLAIFIQAAKKRGEALDHVLLFGPPGLGKTTLAHIIAKELGVNLRQTSGPVLER
                     AGDLAALLTNLDPHDVLFIDEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKID
                     LPPFTLIGATTRAGMLTNPLRDRFGIVSRLEFYENRDLTTIVSRSAQLLQLDMSEEGA
                     EEIAKRSRGTPRIANRLLRRVRDFADVKNNGTIDGGIADAALSMLDVDAQGLDVMDRK
                     FLEAVLHKFGGGPVGLDNVAAAIGESTDTIEDVIEPYLIQQGFLQRTPRGRMATERAY
                     LHFGLPVEK"
     gene            complement(33789..34517)
                     /gene="rpe"
                     /locus_tag="ACFOV4_000396"
     CDS             complement(33789..34517)
                     /gene="rpe"
                     /locus_tag="ACFOV4_000396"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFC7618483.1"
                     /translation="MTTYRIAPSILSADFARLGEEVESVIAAGADLIHFDVMDNHYVP
                     NLTFGPMVCAALKPYASVPIDVHLMVEPVDDLIQSFAKAGASIITFHPEASRHIDRSL
                     SLIRDMGCQAGLVLNPATPVYLLENVLDRLDMVLLMSVNPGFGGQSFIPYTLEKIRQV
                     RAMLDRYEEKSGRRIAIEVDGGIKTDNIAAAAQAGADTFVAGSAIFGKPDYKAVIDAM
                     RAELEKSGRLNLAPMIEIEMPSEN"
     gene            34828..35262
                     /locus_tag="ACFOV4_000397"
     CDS             34828..35262
                     /locus_tag="ACFOV4_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spy/CpxP family protein refolding chaperone"
                     /protein_id="HFC7618484.1"
                     /translation="MPLPAPCRFAKPAASFLSMALLSCQLSHAATAYIPLNDFQPNCD
                     IRRLGLTQGQHNELRKIRAAFKMAGDRARLKVMHSEHSRRRSVVEIISSDVFNRNEAR
                     DYVESRYLSGMDFAVDELEIQHRFFHILTPQQQQMWLSSCLK"
     gene            complement(35275..36139)
                     /locus_tag="ACFOV4_000398"
                     /pseudo
     CDS             complement(35275..36139)
                     /locus_tag="ACFOV4_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241590.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(36147..36764)
                     /locus_tag="ACFOV4_000399"
     CDS             complement(36147..36764)
                     /locus_tag="ACFOV4_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HFC7618485.1"
                     /translation="MFTGIVQGLGKLTAIHRPSEAFQTYVVELPQEAADNLQRGASVA
                     NNGCCLTITEIEGNRVSFDLMAETLAKSNLGLLKEGDCVNIERAARFGDEIGGHVMSG
                     HIMATVPIVEIERDGFNRTVWFSLPHELKPYILTKGFVGLDGCSLTIGKVEDGRFNVH
                     LIPETLERTLFGSRKVGDRINIEIDPNTQAIVDTVERLMAQRYAK"
     gene            complement(36927..37541)
                     /locus_tag="ACFOV4_000400"
     CDS             complement(36927..37541)
                     /locus_tag="ACFOV4_000400"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HFC7618486.1"
                     /translation="MKTSNFSKRTSAMKTFALILAGGQASRMGGEDKGLALLGGKALI
                     DHVIDRVRPQVSHIAISTNRNLEEYARRSPHIFPDARQWQHFGPLSALCTAANDLQLA
                     TADWLLVVPCDMPYLLGDLVARFETVSKRTPLCNAYYVETPITMHYNIMYIRPQILQS
                     AIPYLFSGMKTLRSWLQQQRARSVRFEFDGHFADLNTQIDLQEG"
     gene            37747..39519
                     /locus_tag="ACFOV4_000401"
     CDS             37747..39519
                     /locus_tag="ACFOV4_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite sensor histidine kinase"
                     /protein_id="HFC7618487.1"
                     /translation="MILPARFSDGISLSLRLKLLTGLWVGLAALSVVLTLLLSLRLEN
                     AASVIEEAGNLRMQAYRLAYMAGEGSPRAQIDNQVAEFEKSLKRIAQSDAIHPLIPSD
                     TPLAYDLIQSMLIIDWQAHILPPLQSYRRPTQVDLYRFAGNIELFLQALENANEKNTW
                     WLRRFQWAIMLMTLVSSVLMLFWHQIWVIRPLQALREGAERIGRRCFDIPVPEGGTPE
                     FKQVGRCFNQMGGRLKILYDDLEGQVAEQTRSLEKQNQNLTLLYQTTRDLHQSYIPQQ
                     AAEHFLNRILPAVGADSGRVCLDGGSDVYVSIHHADCGTAASDLGKYHEEIFPIEYQN
                     ETLGRLLLSFPNGISLDEDDRILLQTLGRQLGVSLAGAKQEEEKRLLAVLQERNLIAQ
                     GLHDSIAQALTFLNLQVQMLETAFAENKREEAAENIGFIKTGVQECYEDVRELLLNFR
                     TKISNKEFPEAVADLFARFTQQTGITVETAWENGSFLPPQEAQLQMIFILQESLSNIR
                     KHARATHVKFTLSEHGGRFTMTIQDNGQGFDTEKIGEPTGSHVGLHIMQERAKRIHAV
                     LEIRSQPQQGTTVSLTGASEESLK"
     gene            39516..40172
                     /locus_tag="ACFOV4_000402"
     CDS             39516..40172
                     /locus_tag="ACFOV4_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFC7618488.1"
                     /translation="MTIKIILIDDHTLFRSGIKALLSRQHGFEVIGEAADGLSGIKMI
                     SRLQPDVVLLDLDMPGMNGREALSQIISINPQQAVIMLTVSEDSDDLTECIRIGARGY
                     LLKNINADFLLESIRKAAEGDNVFSPEMTAKLVKSLISPQPAQGTQALSSLTPRELEI
                     LGYLAAGHSNKIIARHLDLAESTVKVHVQNLLRKLNLSSRVQAAVYAIRHNVPQPMLE
                     "
     gene            complement(40646..41680)
                     /gene="purM"
                     /locus_tag="ACFOV4_000403"
     CDS             complement(40646..41680)
                     /gene="purM"
                     /locus_tag="ACFOV4_000403"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFC7618489.1"
                     /translation="MSTSLSYRDAGVDIDAGDQLVENIKPFAKRTMRPEVLGDLGGFG
                     ALVEIGKKYKNPVLVSGTDGVGTKLKLAFDWDKHDTVGIDLVAMSVNDILVQGAEPLF
                     FLDYFACGKLDVPRATDVIKGIAQGCEESGCALIGGETAEMPGMYPVGEYDLAGFAVG
                     VVEKENVITGRSIGAGDVVLGLASNGAHSNGYSLIRKIIERDNPDLDAEFDNGKTLRE
                     AVIAPTRLYVKPILAALEKFTIKGMAHITGGGITENVPRVLPENTVAQIDAKSWELPK
                     LFQWLQKAGNVETQEMYRTFNCGIGMVVIVAAEDADAVQGLLGEQGETVYRLGLIRER
                     QGDEHQTQVA"
     gene            41921..42109
                     /locus_tag="ACFOV4_000404"
     CDS             41921..42109
                     /locus_tag="ACFOV4_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618490.1"
                     /translation="MADERKGFFDAIIKINIFFFPVETPALGAVNLIAGGSTRFRFGA
                     EQMAALYVPFCVLKHIGR"
     gene            complement(42200..42284)
                     /locus_tag="ACFOV4_000405"
     tRNA            complement(42200..42284)
                     /locus_tag="ACFOV4_000405"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42248..42250),aa:Leu,seq:tag)
     gene            42438..43112
                     /locus_tag="ACFOV4_000406"
     CDS             42438..43112
                     /locus_tag="ACFOV4_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618491.1"
                     /translation="MPAALIKDFLLTQGLKLPLDEVRAAYLTAQTVMGMGTASIDRSV
                     LWRSDEGWKLADYLSCDNVREDALKRLFMALDSVFSRSTGVRSAAVYALMPSENQAFQ
                     LICLSQQGEGLENIWNLDENVADVSLACRCAQSGWMNVASDVRRWLDLGELSGERNHA
                     SAAQISIPICTESGGVLGVVHVEFECAECADEAAQAEWVALALALSEPLKQLLGITAA
                     EGDENV"
     gene            43105..43698
                     /gene="ribA"
                     /locus_tag="ACFOV4_000407"
     CDS             43105..43698
                     /gene="ribA"
                     /locus_tag="ACFOV4_000407"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HFC7618492.1"
                     /translation="MSELLNYVASCRLPTEWGVFTMHGFEEANGQEHVALTVGDFSDG
                     NPVLTRIHSECLTGDALFSRKCDCGPQLEAAMRAVQTEGRGIIVYLRQEGRGIGLINK
                     IRAYHLQDQGMDTVEANLALGLPVDARDFRLAQSIYEYLGIRSVKLLTNNPEKIQTLK
                     DAGINVVERIPLHVGENLENKRYLQTKADKLGHLMSE"
     gene            44019..45032
                     /locus_tag="ACFOV4_000408"
     CDS             44019..45032
                     /locus_tag="ACFOV4_000408"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC7618493.1"
                     /translation="MIFSIIVPIYNVEKYLRCCVDSVLAENFADYEMILVDDGSPDGC
                     GKICDEYAGKYPHIKVIHQENGGLSDARNAGIRAAKGDYLIFLDSDDYWADTNRSKNA
                     GGGILFDLQQLADKKVDLILHPSSLNYHVIPKGADFSDNDFVRHFETLVEGRYYIANA
                     WTKIVRREIIIKNNLFFPKGYIHEDFPYSLQLARFIKTFAFYDNPFYQYRVLGGSISH
                     NIKYKNFSDVLTHLDRGVDFLVENKNSPIYGGLQKFVFDNIGYLRSILVRLYFSKNII
                     LIYRKYFSFKEKCRKIFGAKTIRPVFIGKTAFIIGLPILRLLVPPMLYPAIKAVYQKF
                     FSE"
     gene            complement(45011..45145)
                     /locus_tag="ACFOV4_000409"
     CDS             complement(45011..45145)
                     /locus_tag="ACFOV4_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618494.1"
                     /translation="MPSEAGFVASDGIAAILAGRGLFVPTSRALLIWGLPEAYSEKNF
                     "
     gene            45254..46591
                     /gene="ribBA"
                     /locus_tag="ACFOV4_000410"
     CDS             45254..46591
                     /gene="ribBA"
                     /locus_tag="ACFOV4_000410"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HFC7618495.1"
                     /translation="MTDTAGLRRRNLRQWIAEHYGGLQTRFAEAVALNTGELSALLKN
                     KSFGEKKARKIEQAAKMPAFWLDTEHTARPPEHTGKHTMSHISPIPEILADIKAGKMV
                     IITDAEDRENEGDLLMAAQFVTPEAINFMIKHARGLVCLPMDGEMVEKLGLPMMTQKN
                     GAQYGTNFTVSIEAAHGITTGISAADRALTIQTAVSPTAKPEDIVQPGHIFPLRAQKG
                     GVLVRAGHTEAGVDLAQMNGLIPASVICEIINDDGTMARMPELMKFAEEHKLKIGTIA
                     DLIEYRSRTESLLEDMGNAPVQTPWGEFQQHVYVDKLSGETHLALVKGTPSADTETLV
                     RVHEPFSVMDFIQANPRHSWSLPKALERIQQAESGVVILLHRTEDGAALLDRTLPKGA
                     NQAYKWDSKSYGIGAQILAGLNVKKLRVLGQPSSFTGLTGFGLEVVGFEEAEK"
     gene            complement(46751..46867)
                     /locus_tag="ACFOV4_000411"
     CDS             complement(46751..46867)
                     /locus_tag="ACFOV4_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFC7618496.1"
                     /translation="MPSERLSDGILFGLENTYAVLSLKERIQKTKATGIYRK"
     gene            complement(46899..48500)
                     /locus_tag="ACFOV4_000412"
     CDS             complement(46899..48500)
                     /locus_tag="ACFOV4_000412"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HFC7618497.1"
                     /translation="MTEQHFTEQTKSLIDSLKTICANYGLGNDGNEFKIISQAFLYKF
                     LNDKYDFEVKQIRKENPDEPIEFINMDIEGKTAVLKPEHSIKYLSERQNGADFAKLFD
                     DTLTDIAAHNAELFSVKTEGGAKIVLFERISQYITDEGRRDDFCHALISKLAGFSFEA
                     IFAQKFDFFATIFEYLIKDYNSNSGGKYAEYYTPHAVARIMADILVPKEVRGQIRSVD
                     VYDPSAGSGTLLMNVAHAIGEDKCMIYTQDISQKSSNLLRLNLILNNLVHSLNNVVQG
                     NTILSPAHKDTSGRLKKFDFIVSNPPFKLDFSDFREQLEGEENRERFFAGIPKIKAKD
                     TDKMEIYQLFIQHILFSLKENGKAAIVLPTGFITAQSSIDKKIREYLVENKMLAGMVS
                     MPSNIFATTGTNVSILFIDKANKDNVVLIDASGLGEKIKDGKNQKTVLSREEEQKICN
                     TFTHKQAVEDFSVVVGYDEIKAKNYSLSAGQYFEVKIDYVDISADEFAQKMAGFSADL
                     DKLFAESAKLEKEIKDRLAMLEFNS"
     gene            complement(48548..49741)
                     /locus_tag="ACFOV4_000413"
     CDS             complement(48548..49741)
                     /locus_tag="ACFOV4_000413"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFC7618498.1"
                     /translation="MKRQITIGEIAEINANSLTQKDMFQEIMYLDTGNITRNEIDNIQ
                     VLNVMMDKIPSRAKRKVKDKTIIYSTVRPNQEHYGFLENPGDNFIISTGFSTIDVYDE
                     NTDEKFIYYLLTQKHITDYLHTIGENSVSSYPSINPDDIANLKFAVPDLKTQQSIAAV
                     LSALDKKIALNKQINARLEDMAKTLYDYWFVQFDFPDANGKPYKSSGGEIVFDETLKR
                     EIPKGWGSIELQSCLAKIPNTTKILNKDIKDFGKYPVVDQSQDFICGFTNDEKSILNP
                     QDAHIIFGDHTRIVKLVNFQYARGADGTQVILSNNERMPNYLFYQIINQIDLSSYGYA
                     RHFKFLKEFKIILPSKDISQKYNEIANTFFVKVRNNIKQNHQLTQLRDFLLPMLMNGQ
                     VSVAE"
     gene            complement(49868..52873)
                     /locus_tag="ACFOV4_000414"
     CDS             complement(49868..52873)
                     /locus_tag="ACFOV4_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HFC7618499.1"
                     /translation="MSQTHNENSRVKIPAVLHLMRLGYDYLSLKNENWDKPTNIFPKI
                     FIESLCRINPDLSPDDARRLLTDIRLELDNEDLGQKFYERLTNQSGGKKLIDFQNFDN
                     NSFHVVTELPCINGDEEFRPDITLLVNGMPLVFIEVKKPNNKGGIGEERERMGKRAKN
                     SKFRRFINITQFMIFSNNMEYDDGATEPAQGAFYASSAYGKPVFNYFREEHKLNLAEL
                     LNTLSDGLENNVLQDNNLPVIKHSPEFISNKSPDTPTNRILTSLLCRERLSFLLQHGL
                     TYVKASQGLVQKHIMRYPQLFATLAIEKHLANGGKKGVIWHTQGSGKTALAYYNTRYL
                     THYYAKQGIVPKFYFIVDRLDLLKQAQREFTARDLVVHTIDSREAFAADIKSAQTLHN
                     HAGKAEITVVNIQKFQDDPDVVARNDYDLAIQRVYFLDEVHRSYNPKGSFLANLNQSD
                     VNAVKIGLTGTPLIGVTAGNVNTRELFGDYIHKYYYNASIADGYTLRLIREAISSQYK
                     AQLQAALAQLEVEKGSFDRKEIYAHPHFVRPMLDYILGDFAKFRKTNQDESLGAMVVC
                     DSAEQARQLFEHFQTASDHNFTAALILHDVGTKDERDQWVKDFKAGKTDILFVYNMLL
                     TGFDAPRLKKLYLGRLIKAHNLLQTLTRVNRTYKSYRYGYVVDFADIEREFDKTNRAY
                     WDELSNELGDEIGSYSQLFKTAEEIEQEIADIKNALFDFDTENAEEFCSQISQIEDKK
                     QLLALKKALQTSKELYNALRLQGSHEFLVHLDFDKLNLLYRETAARLDTLNLAEKLQQ
                     GDTAHLLNEALEDVYFQFVKIGEAELKLADDLKDIMRKVREGLAGNFDQDDPEYISLR
                     EELERIFKKKNLAEVGQEEMQANIATLQIVYAKIKELNRQNDLLRHKYGGDAKYARTH
                     KRLMENAAFYGDKLKVFNALNGVKADADQKVLDMEQILDNQNYFEKQMQGIVLKRFRT
                     EQQFPVQPQDIQAINRLLVREYLKESGRM"
     gene            complement(52987..54297)
                     /locus_tag="ACFOV4_000415"
     CDS             complement(52987..54297)
                     /locus_tag="ACFOV4_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFC7618500.1"
                     /translation="MTDLFAREPDAPLAERLRPHTLDDVVGQEHLIGEGKPLRVAVEG
                     GKPHSMLLWGPPGVGKTTLARILAQSFNAQFLPVSAVFSGVKDIREAIDKAEIALQQG
                     RATILFVDEVHRFNKAQQDAFLPHVESGLLTFIGATTENPSFEVNPALLSRAQVYVLQ
                     PLSSDDLKKLIAKVLALPEYQEFTIETDAQKLLVNTADGDARRLLNLLEQLLRAADTR
                     RLKNLTAEFLADSLGAQIRRFDKGGESFYNQISALHKSVRGSHPNAALYWFCRMLDGG
                     TDPRYLARRIVRIAWEDIGLADPRAFQIANDAAATFERLGSPEGELALAQAVLYLAAA
                     AKSNAGYKAYNQMRHFVKENASDEVPVHLRNAPTKLMKELGYGREYRYAHDEPNAYAA
                     GESYMPDGLDEPDFYQPVPRGLEIKIGEKLAWLKSLDEEALKAK"
     gene            54609..>54877
                     /locus_tag="ACFOV4_000416"
     CDS             54609..>54877
                     /locus_tag="ACFOV4_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter"
                     /protein_id="HFC7618501.1"
                     /translation="MEWVSLFSDPQRDDDSLITLKDEKITVKNYIVPWWKKGENFRKL
                     ELITTGKNDNGNLTVNGIYGIQSFADSQLGYTPELLVKSNNDILF"
BASE COUNT        12516 a        14158 c        14272 g        13931 t
ORIGIN      
        1 cgattttttg atatggcggc cggcgcatca tttcaggcca atcgaaacgc ccgtattgaa
       61 agattgcgtt tatttccacc gccgttttaa aggccggcgg tattcggcag acggggcgca
      121 aacggcgttc agacggcatt ttcattcttt cggcgtgtcc gtccgaattg ctttgcccgt
      181 ccgcgcaatc agcccgtgcg gcttgccttg aacggacaaa aaatgccgtc tgaaacccga
      241 aaatcaggtt tcagacggca ttttgccttg aaaaggctgt tcaaatcagc ggtggtagtt
      301 cggtgcttct ttagtgattt gaacgtcgtg aacgtgcgat tcgctcatac ctgcggaagt
      361 gatttccaca aattcggctt tttcgtgcat ttcggcaata ttggcgcaac ccaagtaacc
      421 catactggaa cgcagaccgc cggtcagctg gtggatgatg ttcacaatcg ggcctttgta
      481 aggaacgcgg ccttcgatgc cttcggggac gtatttgtcg gtgctgtcgg ttttgtcttg
      541 gaagtagcgg tcggcagaac cttggctcat cgcgcccaat gaacccatac cgcgatagga
      601 tttgtacgag cggccttgat agagttcgat ttcgcccggc gcttcttccg tgccggcaaa
      661 cataccgccg agcatgacgc tgtacgcgcc tgcggcgagg gctttggcga tgtcgccgga
      721 gaagcggatg ccgccgtcgg caatcagggg aacgcctgtg cctttgaggg cttcggcaac
      781 gttgtggatg gcggtcagtt gcggcacgcc cacgcctgcc acgatacggg tggtgcaaat
      841 cgatcccggg ccgataccga ctttgacggc atccgcaccg gcggcgacca aatccaaagc
      901 ggctttggca gtggcgatat tgccgccgat gacttggatg tgcggatagg tttctttcac
      961 ccatttcacg cggtcaatca cgccttggct gtgcccgtgg gcagtatcga cgacaatcac
     1021 gtccacgccg gcttcgacca aggctttgac gcgctcttcg gtatcgccgc cggtgccgac
     1081 tgccgcaccg acgcgcagac ggccttcgga gtctttgttg gcgttgggaa actcggtggt
     1141 ttttaaaata tctttaacgg taatcagacc tttgagttcg tctttttcgt tcagaaccaa
     1201 aacgcgctcg actttgtgcg tgtgcatcag ttcgcgcgct tcgtctatgc ttgtgccttc
     1261 ggggacggta accagacgtt cgcgcggggt cataatggcg gaaacgggca aatcgacgcg
     1321 gttttcaaaa cgcaggtcgc ggttggttac gatgccgacg actttgccgt tttcaacgac
     1381 gggcaggccg gacattttgc gtttgcgctg cgcacgcatt tccaagactt cgcggatgag
     1441 cgtcgtcggt gcaacggtta cggggtcttt gaccacgccg ctttcgtggc gtttcacttt
     1501 ggaaacggcg cgcgcctgca tttcgggcgg catgttttta tggatgatgc cgatgccgcc
     1561 ttcctgtgcc atcgaaatgg cgaggcgcgc ctcggtaaca gtgtccatcg cagcggaaag
     1621 cagggggagg ttgagtgtga tttcgcgggt gagcttggtt tgaagtttaa cgtctcgcgg
     1681 cagcacggtc gaatgtgcgg gaaccaacaa aacatcgtcg aaagtatagg ctttttctac
     1741 gatacgcata atgctcggtc tttcagtttg tgcaagatgc acggcattat agcacgttac
     1801 cggcggcttg acagtttata ttgtttgcaa tatcccccgc cttcaggcgg catacggcgt
     1861 ggcggcggaa tgccgtctga aggcgggcgt tatgataatt gttccagcag cgtctgcttc
     1921 aatgaggact ggatttttgg gtttttcagg tcggggctaa aaacggtaaa actgtcttcg
     1981 gcgcgttcat ccagtgtgga gattttggca tagcgcaggc tgacgttgtg ggcgaaaaag
     2041 atttccgcca tatcggcgag caggaagggg cggttgacgg cggtaatttc gacggagtac
     2101 cagtcggggt agtcttcttc gggggtaatg gtgatgcttg gcgcgatcgg catgtagcgg
     2161 ctgcggcggc tgatgcggcg gctgtggttt gaggtttcgg caacggtgtg tccgtggata
     2221 aagctgttga gttcggcttc aagcgcgctt tgaatgtcgg ggtagtcttc gggggcgtgt
     2281 tgtgagggaa tttgcacgat gaaggtgtcg aggatgtagt cgtgttcggt gataaaggcg
     2341 cgggcggcga ggatatcgaa gccgtggcgg ctgaaaatgc ggcagagacg ggcaaacagg
     2401 cgcgggccgt tgggcatgaa aaccatgact tgaaagctgt cgcttttggg caggatgcgg
     2461 ctgcggacga tgggggtttc aaagtcgtgg actaggttgg cggcgtgcca caggatttcg
     2521 cgggactggt ggcgggcgaa gtaggcggaa ccgagcgcgt tccaaagctt tttctgctgt
     2581 ttttcgggga cggcggcgcg ggtgagcaag tcggcggctt cttgttggcg gcggccgaag
     2641 agggcgtgcg ggttgccacc gttgcctgcg aggtagcgtc cggcggcatg gaagaggctt
     2701 tccagcaggc tggcgcgcca tgcgttccac agcttgggat tggtaccgcg tatgtcggaa
     2761 atggtcagaa ggtagagcgc gctgaggcgt tcgtgggttt ggacgcgttt gcagaaggca
     2821 tcgagtacgt cggggtcttg gatgtcttct ttttgggcga cgatggacat aagaagatgg
     2881 ttttcgacca gccaggcaag caggtcgctt tcttcttcgg tcaggaagtg gtcggcggca
     2941 aattggcgcg cgtctgagat gccttgtatg gcatggtcgc cgccgcgtcc tttggcgatg
     3001 tcatggaaaa aggcggcaag gtagaggatg tcttgttttt caaaggactg catcagtgca
     3061 gaggcgtagg gcagctcgtg gctgtgcata tccaaggcaa ggcggcggac gttgcggacg
     3121 acggcgagga tgtggtcgtc cacgggatag atgtggaaca ggtcgtgctg gagcaggccg
     3181 acgatttttt cccacgcggg caggtagcgt cccaatacgc cgtagaggtt gaggaagcgc
     3241 agggtttggg tcagtccgtt gccgttgcgg aaaaagccgg cgaagcggtg gcggttttca
     3301 gaattttggt agaagctgcg gttgattttg cgcgtcgcgc cccaccatgc gcgcagggtt
     3361 tgcggttcga gcgcggtaat gtcgttgcgc tgctgcatga tttcgacgat tttgaaaatg
     3421 tgttcgggcc gtctgaaaaa aatatcggtg tgccgcgcgg cgatttggtt gttgacttgg
     3481 atgtagtcgt cgtcaatccg cagggtaacg cgcaacgggg tggaggaaac gcggctttgc
     3541 agcataggcg tgaggatgcc gcccagttgt ttgacggttt taatcgcgcg gtaaaacacg
     3601 cgcatcagtt cttcgctttg gcggcggagg ttcaagcctt cataacccat gctttcggcg
     3661 acttgcggct gcaaatcgaa cagcaggcgg tcttcggcgc gcttggcgtt taaatgcaga
     3721 tggatgcgga tgtgggcgag gcggcggtag ccgtgcgaaa gcataccggc ttcggcacac
     3781 gtcaaaatcc gctgtttgag caggtcgggc aggtcggtcg ccaagccttg cgccttcgct
     3841 atccaaagca gggtgtggat atcgcgcaga ccgcccggac agcttttgat attcggctcc
     3901 aatactgccc ccgaaccttg cgatttggcg tggcggtgtt ccatctccac cagttttgcc
     3961 tcgacaaacg ccgccacatt gcgctgcgcg ttcatttttt ccgctagttt atccgccgtt
     4021 tggcggttgc caaacaaaaa cctagcctct aaaaacgctg tgtcccccgt aatatcattg
     4081 cgcacgcttt cacatagttc atcaacgctg ccgcttttta cagacggcat cagtttgcag
     4141 tcccacaggg tttggacaaa ccgggcaatc tgttcctgaa tgccgtctga aagcggggca
     4201 ggggagacaa ccgccaaatc cacatccgaa cagggataca gttcgccgcg tccgaagccg
     4261 cctaccgcca tcaggcataa cgcgctgttt tgaaaatact ctgcccacaa tgccgccagt
     4321 aaggtttcga gtgccgccgt atattccctg aaaaataccg acacgcggtt ggctttcaaa
     4381 taatgcgctt cggcggcatc gcgctgctgt ttgaaggttt ccagtgctga agacaggttt
     4441 gcaggcattt ttattctttc gattggcggg aaaaagggag gcggatggtt cggcggtcaa
     4501 ataccgcttt cagacggcat ttgtcgggta tcggcggaat tggtcatcag cttcaaccgt
     4561 tcctgcggcg gcagcagcaa ctgatacgcc gccacgccca aagccgccgc cattttttcg
     4621 atattcgaca gggcgatgtt ccagcgtttg cgctcgactg ccgacacata agtcctgtcc
     4681 aaaccgcatt gccgcgccaa ttcttcttgc gaccaaccct tgttcacgcg gaaaagccgc
     4741 atattgtatg ccaataccgc ccgcaaatcc tgttcgtcag gcagttcggc aggcagagtc
     4801 aatttgttgc ccatcatttg cttccagata aatggttaaa gttaagcatt tgctgttacg
     4861 gattttactt cacataaaag ccaaaaaaaa ggggtggcgg cagccacacc caaacacaca
     4921 cacatcaaga ggaaagagat aaaatcagac agattggaaa acagcaaaca agcaccctga
     4981 atttcatatc ggtattatca aacaaaaacc cttatcaggt attgattcaa atcaatttag
     5041 attttattcg caaaccgaaa aagaaaaacg gcatatccgt ttatacggat atgccgtctg
     5101 atggtgcggg ggactgctgt atttggcagt agtttgtgtt ttagtcctct tgcgccgctg
     5161 tttgcaggta gttgggcaga ccgattttgc cgataagctc ttgctgggtc tccagccagt
     5221 ctatatgttc ttcgttggtg tctttttgtt tttccaacaa atcgcggctg acgtaatcct
     5281 gttgcgcttc tgctgtggcg atggcggcaa gcagggcttc gtgtttttcc tgttctttgg
     5341 tcaaatcgca ggcgatgatt tcttcggtgg actcgccaat cagaagcttg cccagttctt
     5401 gcaggttcgg cagaccttcg aggaacagaa tgcgctcgat caaatcgtcg gcagctttca
     5461 tttcaacgat ggactgtttg aagaaatgtt cgcccagttc ttcaaagccc cagtttttca
     5521 aaatacgggc gtgaaggaaa tattggttga tggttaccag cagcaagcct aagtttttgt
     5581 tcagctcgcg gataaccaaa cggtcgcctt tcatacggac tccttttatt ccgaatacgg
     5641 attacagttg gctttggtag tagttgcctt cgccaatcag ctcgatcagg cgcagctgct
     5701 gttccagcca gtgggcgtgg tcttcttcgg tatctttcag ttgggcgacc atcaaatcgc
     5761 ggctgacata gtcttgcgcc tcttcgcaca gtttgatgcc ttttttcaaa gcgtcgcgca
     5821 cttcgtattc ggtttgcagg tcggctttga ggcaggaaac cacgtccgtg ccgatattca
     5881 gctcggcgcg cgccattttc ggcgtaccgc ccagcatcag gatgcgtcgg atgaagtctt
     5941 cggcgtgtgt ggtttcttct tccatctcgt gattgagacg ttcaaaaagt ttggtgtagc
     6001 cccattcgga gtagaggcgg gagtggataa agtattggtc gcgtgccgcc agctcgccag
     6061 acagcaattc gttcatataa tcaacaacag cttgattgcc ttgcataata tctctctttc
     6121 cgtaacttgg ttttcggtat gtctgaacag catctgtgtc gctattcggg atgcgtgcat
     6181 tgtatgcaaa agctgtcggc atgacaaatt ttctatttaa aatacaaaca attatcaaaa
     6241 gaaatagggc gtattccccg atgccttcca aatcagtatg ctgtttctta tcggtttttt
     6301 gtgctgttaa aactaagaat ccatatcatc cataaagaac atttacactt gttaaccata
     6361 gcgaaaagca aatactgtac ggttttttat caaaatttat aatgaatcgt tctcattaac
     6421 cgacagattc ttttgagatt atcggatttt gggaataaat tatgccgtct gaggggcttt
     6481 cagacggcat agacaattaa agctgattaa acaacgcggc agacagcagc gtaggaaatt
     6541 attttttact tcggaacggt attttgggtt taatgatgcc cgcaaccgcc gtggctttcg
     6601 cgtaaggctt cggcagcctg ttcgtcggcg tggtagctgg aacgtaccat cgcgccgatg
     6661 gcggcattgc tgaagcccag ttcgtatgct tctttttcaa agattttgaa ctgctcgggc
     6721 gtaacgtagc gcaggacggg caggtgtccg tctgaaggct ggaggtactg tccgatggta
     6781 atcatttcga tattgtgcgc ccgcatatcg cgcataattt cacgcacgtc ttcgtctgtt
     6841 tcgcccaagc cgaccatgat gccggatttg gtcgggatat gcggcatcat ttctttataa
     6901 cgttttaata agtctaaaga atgttgataa ttagcaccgg gacgggcttt tctgtacagg
     6961 ctcggatggg tttctaggtt gtggttcatc acgtcgggcg gggtttcggc aaggattttg
     7021 agtgcgatgt ccaagcgtcc tcggaagtcg gggacgagga tttcgatttt ggtgttcggg
     7081 ctggtttcgc ggatggcttt gatgcagtcg gcgaaatgct gtgcgccgcc gtcgcgcagg
     7141 tcgtcgcggt cgacggaggt gatgacgacg taacgcaggt tcatggcttt gacggattcg
     7201 gcgaggtttc tcggttcgtc ggggtcgagc atattgggcc gaccgtgtcc cacgtcgcag
     7261 aacgggcagc ggcgggtgca gatgtcgccc ataatcatga aggtcgccgt gcctttgctg
     7321 aagcattcgc cgatgttggg gcaggaggct tcctcgcaaa cggtgtgcat cttttgttcg
     7381 cgcaaaatgt ctttgatttc aaagaatttg cgcgatggga gtttggcgcg tatccattcg
     7441 ggctttttca gtttttcctg aagggggacg actttgatgg ggatgcgcgc ggttttgtcc
     7501 gcgcctctga gtttgatgcc gcgtttgggg tcgtcggttt tgatttcact cattgttgtc
     7561 tgctttcggt gtgaattgtg tttcaaggtg tgcggtaagt ttggcggcga cttcgtccgg
     7621 cgtggggcag ggttggacaa aatccgcgat ttgcgtcatt tccataccgg cgtagccgca
     7681 ggggttgatg tgggtaaacg ggcttaaatc catattgacg ttgagcgcaa gcccgtgata
     7741 gacggagccg tttttgatac gcagccccag tgaggcgatt ttgcgttctc cgacataaac
     7801 gccggggcgt ttggggtctg ccgccgcttc gatgccgtat tctgccaatg tggcgatgat
     7861 gctgttttca agcgcggaaa cgatgtttct aacactggtt ttgcgccgtt tgaaatcaat
     7921 catcgtataa acgaccaatt gcccgggccc gtgataggta atctgcccgc cccggtcgat
     7981 ttggacgacg ggaatgtcgt cgcgaatcag caggtgttcg ggttttcccg ccagtccttg
     8041 tgtgaacacg ggcgggtgtt cgacgaccca cagttcgtct tcggtgtcgg cattccgtcc
     8101 ggcattaaag gttttcatcg cttcaaaagt cggcagatat tcgaccaaac ctttgtgtat
     8161 gactttcatc tcaaagtacc actttgacca gttcgtgcga agtcagtgcg cggtagatgt
     8221 tgtccaattg ttcttggttt tcaaccttta tctgaacggt ggcgccggta tagttgcctt
     8281 tgctgctcgg acgcgtggtg atgtggtgcg cctgcgtgtc gggggcgtgg aggcggacgg
     8341 tgtctaaaac cgcctgctcg aactcgggat gcaccgcgcc cattactttt aatgagaagg
     8401 tgcagggaaa ttcgatgagg gatgttttgt ttttttgttc ggtcatgatg tgctgcctta
     8461 tcgtgtacgg tatgccgtct gaaggcgggt ttgcctttca gacggcatcg gatgtgcgtt
     8521 attttagcct aaaccgcgat aacaggctat cgggaaggcg gaggcttttt tgacggcgcg
     8581 gcggttctgc tatactggcg cgcaatatta tttttagaag ggtggttttt atgtatcgga
     8641 ggaaagggcg gggcatcaag ccgtggatgg gtgccggtgc ggcgtttgcc gccttggttt
     8701 ggctggcttt cgcacttggc gacacactgg ctccgtttgc ggttgcggca gtgttggcgt
     8761 atgtgttgga tcctttggtc gaatggttgc agaaaaaggg tttgaaccgt gcatccgctt
     8821 cgatgtctgt gatggtgttt tccttgattt tgttgttggc attattgttg attattgtcc
     8881 ctatgctggt cgggcagttc aacaatttgg catcgcgcct gccccaatta atcggtttta
     8941 tgcagaacac gctgctgccg tggttgaaaa atacaatcgg cggatatgtg gaaatcgatc
     9001 aggcatctat tattgcgtgg cttcaggcgc atacgggtga gctgagcaac acgcttaagg
     9061 cgtggtttcc cgttttgatg aggcagggca gcaatattgt cagcagtatt ggcaacctgc
     9121 tgctgcttcc cttgctgctt tactatttcc tgctggattg gcagcggtgg tcgtgcggca
     9181 ttgccaaact ggttccgagg cgttttgccg gtgcttatac gcgcattaca ggcaatttga
     9241 acgaggtatt gggcgaattt ttgcgcgggc agcttctggt gatgctgatt atgggtttgg
     9301 tttacggctt ggggttggtg ctggtcgggc tggattcggg gtttgcaatc ggtatggttg
     9361 ccggtatttt ggtttttgtt ccctatttgg gcgcgtttac aggactgctg ctggcaaccg
     9421 tcgccgcctt gctccagttc ggttcgtgga acggcatcct atcggtttgg gcggtttttg
     9481 ccgtaggaca gtttctcgaa agttttttca ttacgccgaa aatcgtggga gaccgtatcg
     9541 ggctgtcgcc gttttgggtt atcttttccc tgatggcgtt cggacagctg atgggtttcg
     9601 tcggaatgtt ggcaggattg cctttggccg ccgtaacctt ggtcttgctt cgcgagggcg
     9661 tgcagaaata ttttgccggc agtttttacc ggggcaggta ggcggttccg aaacatatag
     9721 tggattaaca aaaatcagga caaggcgacg aagccgcaga cagtacaaat agggcaacgc
     9781 cgtactggtt tttgttaatc cactatattt gaagcggaat acaaccttgc ccgggtttaa
     9841 ataaaaatgc cgtctgaacc ccgaaaactg gacttcagac ggcattttca tcacggctta
     9901 tttggcggtt ttgctgctgt cgataatttt cataccggca gaaatcaggc tgccgatgtc
     9961 ggcaacattg gcgggcataa tcagcgtatt gctttctttg gcaagattgt tgaacgcggc
    10021 gacgtattgt tccgcaatct tcaggttgac cgcatccgca ccgccttggg tttgaagggc
    10081 ggcggcaatt tgacggatgg cttcggcatt ggcttcggca acaaggcgca aggattccgc
    10141 ttcacctttg gcgcggttga tgcgggcgat tttctcggca tttgacgcat tgaccgcagc
    10201 ctgagcctcg ccttcggatt gttggatttc ggcttcgcgc tgaccgctgg caaggttgat
    10261 ttgttcgatt ttacggcctt cggattcggc gatacgggcg cgtttttcgc gttcggcggt
    10321 aatttgcgcc tgcattgagc gaaggatttc ttgaggcggc accaagtctt taatctcata
    10381 acgcaaaacc ttcacacccc aagccccggc cgcctcgtcc aaagccgcaa caacagtact
    10441 gttgatttcg tcgcgttctt caaacgtttt gtccaactcc atacgcccga taacggaacg
    10501 cagcgtcgtt tgggcaagct gggtaattgc catgatgtag ttgctcgaac cgtatgaggc
    10561 gagtttgggg tcggttactt ggaaatagat gatgccgtca acagtcagct gcgtattgtc
    10621 gcgcgtgatg cagacctggc tgggtacgtc taaagggatt tctttcagcg aatggcggta
    10681 ggcaacgcgg tcgataaagg gaatcaaaat attcaaaccg gccgtcaggg cgcgatggaa
    10741 acgcccgagc ctttcgacaa cgtggacttc ctgttgtggg atgacaacaa aggatttgaa
    10801 accgaaaacg gcaacggctg ccaacaagat aatgaaaaat tccataattc ctccgagtgt
    10861 taaggttttg cgatgataag aaggttgcct tccttgcgga cgattagggc gcgcgttcct
    10921 ggttcaagct cttcttgccc cgtattttgc gcctgccagt gcgtaccgcg ataaaaaact
    10981 tcgtaacggt tgccgcctgt gtgtcggagg atttcgacat attgtccggc atccaaatcc
    11041 tgatatgaat ccgtttcaac ttttctaacg gcggttttgg cgtgtacgaa ccaaataccc
    11101 agcgcggaaa gcagagcggc ggtcaagacg gcggcaggcg tgctgctggt cagcccgtaa
    11161 gcaatgcccg aacccgccaa agccgcgctg acaaccaaaa gataaaccgt tcccgtcaat
    11221 aattcgatga ttaagacggc aacagcggca acaaaccata cagtcataca tttccccaca
    11281 aagcgcgtcg tttgacaaaa taacgcaata tcagcagtat agccgaattt gaaaggatag
    11341 ggcagatatg gacacttggc acgatgcact cggcggcgaa aaacagcagc cgtattttca
    11401 ggaaatttta aatgcagtca ggcaggaacg tttgtcggga caaatcatct atccgccggc
    11461 ggcggatgtg ttcaacgcat tccgcctgac agcgttcgac cgggtcaaag ccgtcattct
    11521 cggacaagat ccgtatcacg gggcagggca ggcgcacggt ttggcatttt ccgtccggca
    11581 gggtatccgc ataccgccgt ctttactcaa tatctacaaa gaattggaaa ccgacatcga
    11641 aggcttttcc atacccgcgc acggctgcct gacagcgtgg gcggagcagg gcgtattact
    11701 tctgaacacg gttttgacgg tgcgtgcagg acaggcgcat tcgcacgccc ttttaggctg
    11761 ggaacgcttt accgataccg tcatcaggca gcttgcgaca caccgcaagc atcttgtctt
    11821 tatgctgtgg ggtgggtatg cacaacaaaa aaggaaactg atagacagtc aaaaccattt
    11881 gatattgacc gcaccgcatc cgtctcctct gtcggcatat cgcggttttt tcggctgccg
    11941 ccatttttca caggcaaaca gctatttgag ccggcacggt atcgatccga taaactggaa
    12001 gctgtgaatg ccatctgaat gccaagttgc ttaaacccca ctgaaggctg cttttgaaac
    12061 cggaaacaaa gtgattaagg aaaaccggcc cataatgcaa aaccgtctga atcctagggt
    12121 tcagacggca ttttttgccg ccatttccaa aaacaacttt tgttcgcctg ccgacaaatc
    12181 cgacaaagtc gtttggttga gggctttggc aataatttaa cataatatac attatgcgaa
    12241 ctatcggaaa cagttgtacg tgtccctgtg gtctttccaa gtaggaaaat taaagtatgg
    12301 acaatgcggc tgaatgtata gcccggagca tccgcgtatc cgaaggtact gaacgatatg
    12361 ccctgcatcc ctttcgatgc ttccatccag ccggtattgg gaaatacgtt gaccttcaat
    12421 ataatataca ggcagccgac acacaggata tgccgctgct ttttcatcat ttcttctgtc
    12481 aaatccttgg aacggtcgat ttgaaaacac ggctttacat acgtcccaat tctctttgca
    12541 gtgcttggat attttgctgc ctgtccaata cattgctttg taatgcattt atttcttgat
    12601 ggttgatgtt gccgcccttt gccagacgtg cttgtgataa cattttttgg gcttcagtca
    12661 gggctttgcg ttcgttgctc aattctgctt cgagaatgga gcgtctgctg ttgtttacag
    12721 gtgcttgttg aggcgggggc gtattggatt ttgccggctt ggatactgtt ttgaccgggg
    12781 ctttatattt gacagcctgt ccgccgtttg acggtgatgg tgtcggttcg gatgtttggg
    12841 gcgggatata gcgttcgctg ctgtagttgc cgattggggg caaatcggtt gagaggcagc
    12901 ttttggacgg cttggtggtg taaacggttt ctccgttgat tgtgcaggtg tagattttgg
    12961 ccgcattcgc acccaatggg cttgaaatca gggaaaagtt gattaggatt aaggggagtt
    13021 ttgatttcat aatgtgcttg atgctcggat aattatttga ttttttggta ttttttgtaa
    13081 tgctttcttg gcgttttacg ggcttttctt ttcggttgtt tgcttttgat tttctttcgg
    13141 ggctttggca gcctgcttgt tctttttccc ggcaggtttt ttgtttttct ttttactttc
    13201 tatgtgtatt ttggcttctt aactgagttt tttaattttc aggcggtatc cgcctccctg
    13261 atggctgctg attttaggta aatccgcatc ggcgcacgat cctgctgggg ccgatgtata
    13321 tacgcttttg ccatttgagt tgcaatggta tacggaggct tgcgccgccg cgccggaaag
    13381 ggacaggaga cccaaggcgg caaaaagtct gatgtttata ccggtaaaag gcggtgataa
    13441 cgcccgaatt ataccgttat tggcaggcaa agataagcac cctgtccgcg cttctttatc
    13501 gctcggcaaa ctgtttctcg atttcagttt caatccgttc caattcttct tgacaagcca
    13561 gccaaacctc ttcgatttgg gcaagttgtg ttttgacttt tgccagcagg gataaggtat
    13621 tttgcaattt ttctttgttt gcttcaaggt aagcgtcttc ttgtgctaaa aatgcttcac
    13681 atgccgtctg aatttcggaa agctgcgcca tttctttttc ggcacggtct attttctgct
    13741 gtatcggctt gccgcgtcgg gctttttcct gacggatttg cgcttcgatg cgcttggtgt
    13801 ctttgcggct ttggctttgt gcggatgctg cgggtgcggc ggcggcgttt tcctgtgcca
    13861 aacgccattg gcggtaatcg ttcaaatcgc cgtcgaagtt cttcagacgg cctttgtcga
    13921 tcaggaggaa gctgtcggta gtcgcttcaa gcaggctgcg gtcgtgcgat acggcgatta
    13981 atgcgccttg gaaactttgc aacgcgagcg ttaaggcgtg gcgcatatcc aagtccaaat
    14041 ggttggtcgg ttcgtcaagc agcaacaggt tcggcttttg ccagataatc atggcaaggg
    14101 caaggcgggc tttttctccg ccggaaaaag gttcggtttt ctgtaacgcc atatcgccaa
    14161 caaaattgaa gccgccgagg aaatttcgga tttcttgttc gcgtacttcg ggagaaagct
    14221 gctgaatatg ccaaacaggg ttttggtcgg cgcggatggt gtcgagttgg tgttgggcaa
    14281 aatagccgat attgagtttt tcggaacgga tgatgctgcc ggaaagcaaa tcgattttgc
    14341 ctgccaaggc tttgataaag gtggatttgc cgctgccgtt gacacccaat agcccgtagc
    14401 gtgcgccgct ttccagcgac agggtaatgt cgtgtaggac agttttgcct tcgtaaccca
    14461 aatcagcgtg ttctagcttt aacattggtg gctttggctt tgaagcggtc gataaaggat
    14521 tgcaaatgtt tgatttgcgc ctgctgtttg acataggcag cttgttgttg cgcgagacgc
    14581 tgcgcgcgtt cgttttggta aaaatcgtaa ttgccgccgt attgcgtgaa tttttgctgc
    14641 gataattcaa tggtttgggt agttgccgcg ttgagaaaat cgcggtcgtg ggaaatgatg
    14701 atttgcgtgc agggtaaaga agcaagatgg ttttccagcc acaagacggt ttccaaatcc
    14761 aagtggttgg tcggttcgtc caaaagcagc aaatcggcgc ggcaaatcag ggcttgggcg
    14821 agattgaggc gcatacgcca gccgccggaa aaggatttga cggggcggct gtgttcttct
    14881 tgcgaaaaac ccagcccgtt caacaatttt gccgcgcggg ccggcgcggt ataagcgtcg
    14941 atttcttcca atttggcatg atattccgcc tgcttcatgc cgtcattttg cgcttctgcc
    15001 tgcctcaatg ccgtctgaaa agcctgcaac tcggcatcgc cctgcaaaac gtaatccaaa
    15061 gcggaaatat ccaaatcggg cgtttcttgg gaaacggaag cgagccgcca gtttttcgga
    15121 atcgagacat cgccgccgtc ctgagtgatt tcacccttga ttaaggcaaa caggctcgat
    15181 ttgcccgttc cgtttttgcc gatcaaaccg acgcgctgac cgggattgac ggtagcgttg
    15241 gctttgtcga gcaggacttt caaaccgcgt tgcagggtga ggtttttgat ttcaatcata
    15301 acggaaacat cgtcgggcgg gaaaagcccg tattttacct gaaagtcagt gccgatgccg
    15361 tctgaaacgg gaaatttacg gctgaagcca agcccaagcc ctgcgccctt ccgagtgcag
    15421 gaaaaccaat gtcctgaatg ccgaatcggt attcatgcat tccacgctga ttccgattcg
    15481 ggaaaaatcc gccatgattt tgggatggat aaactcctga gccgcgcccg tcccgataat
    15541 caatatttcc ggatagtcaa caggtttgat gtcggacaac aggttttccg gagtcagatc
    15601 ggacaaggtt cggcattgcg acaggcagac cgaatcctta tgtacaagca cgggtttatg
    15661 gaaactttgc cccgccagcc ggattccgcc cgcaccgcat tcatattccg caaactgtcc
    15721 gtctatcgga ttttcttcaa acaacatttt tttaccccgt cgccgcatca tctacaccga
    15781 aaggggtgca aaatcagaca aattcatgta ggattggcag atttcatctg actcgcctgc
    15841 cgatttcaga cggcatttga ttcaaagtgc ggcaccatta tatcggcagc ggatattttc
    15901 gtctttcaat atttacattt cagtcggctt acaaggagac acaatgaagc cagtaaacat
    15961 cggtctttta ggtttgggta cggtcggcgg cggtacggct gccgtgttgc gggacaacgc
    16021 ggaggaaatt tcccgtcgct tggggcgcga aatccgtatt tctgccgtat gcgacttgag
    16081 cgaagaaaaa gcccgccaaa tctgcccgtc cgcagccttt gtcaaagatc cgttcgaact
    16141 ggtcgcgcgt aaagacgtcg atgtcgtcgt cgaattgttc ggcggcacgg gcattgccaa
    16201 agatgcggtg ttgaaagcca ttgaaaacgg caaacacatc gttaccgcca acaaaaaact
    16261 gctcgccgaa tacggcaacg aaatcttccc gctggcggaa gaaaaaaatg tcatggtgca
    16321 atttgaagcg gcagtagcgg gcggtatccc aatcatcaaa gccctgcgcg aaggtttggc
    16381 ggcaaacagg attaaatcca tcgccggcat tattaacggc accagcaact tcatcctctc
    16441 cgaaatgcgt gaaaaaggca gcgcgtttgc cgatgtactg aaagaagcgc aggcactggg
    16501 ctatgccgaa gccgacccga ccttcgacat cgaaggacat gacgcgggcc ataaaatcac
    16561 catcatgagc gcgctggcat tcggcacgcc gatgaacttt tccgcctgct acctcgaagg
    16621 catcagcaaa ctcgacagcc gcgacatcaa atacgccgaa gaacttggct accgcatcaa
    16681 actgttgggc atcacccgca aaaccggcaa aggcatcgag ctgcgcgtcc accctaccct
    16741 gattcccgaa agccgcctct tggcaaacgt caacggcgtg atgaacgccg tgcgcgtcaa
    16801 cgccgatatg gttggcgaaa ccttatatta cggcgcgggc gcgggcgcat tgccgaccgc
    16861 ttccgccgtg gttgccgata tcatcgacat cgcccgcctg gttgaagccg ataccgccca
    16921 ccgcgtaccg catctggcgt tccaacccgc gcaagtccaa gcgcaaacca tcctgcctat
    16981 ggacgaaatt accagcagct actacctgcg cgtccaagcc aaagacgaac cgggcacgct
    17041 ggggcaaatc gccgcgctgt tggcacaaga aaacgtgtcc atcgaagcac tgattcaaaa
    17101 aggcgtgatt gatcagacca ctgccgaaat cgtgattctg acccacagca cggtcgaaaa
    17161 acacatcaag tcggcaatcg cagccatcga agcactggat tgcgtggaaa aaccgattac
    17221 catgatccgc atggaaagcc tgcatgactg agccgaaaca cgaaatgccg acggaagagc
    17281 aggttgccgc gcgcaaaaaa gcaaaagcca aaatccgcac catccgcatt tgggcatggg
    17341 tcattttggc gttgctcgct tcaaccgccc tgctctccca atgcgcgatg tccaaaccgc
    17401 aggcaaaaca gaaaattgtc gagtcttgcg tgaagaatat tccgtttgcc gaaaaatggc
    17461 aaaacgattt acgggcccgc ggtttagatt caaacaatac ccgccttacc gtcgactact
    17521 gcaaatgtat gtgggagcag cctttggaca gattgagcga gaaacagatt agatccttcg
    17581 gcaaactcgg cgcacaagaa cagcttgacc tgctcggcgg cgcaaatgcc tttgaagcac
    17641 gtgacaagca gtgtgttgcc gatttgaaat cagaataatg tggaccgata aaaaagccga
    17701 ttctttaaag aatcggcttt tttcataaaa aacggcttac agtgcgtctt tcaaagcttt
    17761 gccggcgcgg aatttaggcg ttttggcggc ggcaatggtc agaggctcgc cggttttggg
    17821 gttgcggcct tggcgttccg cacgttcgcc cacgtagaaa gtaccgaaac cgaccaaagt
    17881 aacggtgtcg ccttgtttca gggcggtggt tactgcattg gtagtggcat ccaaagcttt
    17941 ttgtgcggcg gctttggaaa tgtcggcttc ttgagcaatc gcttcgatca attcagactt
    18001 gttcacaatc agtcccttcc tgtcttaaaa aatgatgaaa tgcccgaata ctcggggttt
    18061 gtactgcttg agcaactttc gctttatagc aattctgaaa ttgccgtgtc aagcaaaaaa
    18121 tacggaatca ccctatttga caggctttca ggacgaaacc gcatttttac aacacatttc
    18181 ctgcgtttca atgtttggtt gccctgctgc ggggttttgg ttttgaagcg gattccgccg
    18241 ccgcttccgc accagaaggt tctgcccaag gctcaggctg gctttccaaa cccagagcca
    18301 atacctcgtc tatccatttg accggatgga tggtcaggcc ggttttcacg ttttcaggga
    18361 tttcttccaa gtctttgagg ttgtcttttg gaattaaaac gtgtttgatg ccgccgcgaa
    18421 gcgcagccaa cagtttttcc ttcagaccgc caatcggcag gacttcgccg cgcagggtaa
    18481 tttcgcccgt catggcaaca tcggcgcgca ccgggatttt ggtgaatgca gacaccatcg
    18541 ccaaagtcat ggcaatgccc gcactcggac cgtctttcgg cgtcgcacct tcgggaacat
    18601 ggacatggat gtcttttttc tcgtaaaaat caggagccaa gcccactgat tccgcgcggg
    18661 agcggacaac cgaccacgct gcagacacgg attccttcat cacatcgccc aactggccgg
    18721 tgcactgaat cacgccctta cccggcaatg ctgcggcttc gacggtcagc agttcgccgc
    18781 cgacttctgt ccacgccaga ccggttactt gtccgatacg gttttcgctt tcggcaacgc
    18841 cgtaatcgaa gcggcgcaca cccaaatagt cgtgcagatt tttctcattt actttaaccg
    18901 ctttaggttt ggctttgctg gttttcttgg tttcagacaa cctcttctta tcttcgtcca
    18961 aggtaatctg catcaccacc ttgcggcaga ttttggcaat ctcgcggtcg agcgaacgca
    19021 cgcccgcctc gcgggtgtag taacggataa tatcgcgcac cgcgctttct tcgattgcca
    19081 attccccttc tttcacgccg ttgcgcttca tttgcttcgg cacgaggtac tgcatcgcga
    19141 tattgatttt ttcgtcttcg gtgtagccgg acagacggat gatttccata cggtcgagca
    19201 gcggggtcgg gatattcagg ctgtttgaag tcgcaataaa catcacatcg ctcaaatcgt
    19261 aatccacttc ggcataatga tcggcgaact tgttgttttg ctcgggatca agcacttcga
    19321 gcaacgcgct ggcgggatcg ccccggaagt cgctacccaa tttgtcgatt tcgtcgagca
    19381 ggaacaatgg gttttttacg ccggcttttg ccatattctg cagaatctta ccaggcatag
    19441 agccgatata ggtgcggcgg tgtccccgga tttcgttttc gtcgcgcacg ccgcccaaag
    19501 ccatgcggac atatttccgc cccgttgctt tggcgatgga ttcgcccaaa gaggttttgc
    19561 ccacgcccgg aggaccgacc aggcacagaa tcgggccttt gagtttgtcc atacgttttt
    19621 ggacggcgag gtattccaaa atccgttctt tgactttttc caggccgtag tggtcggcat
    19681 ccagcaccag tccggctttg gcgatgtctt tgctgacgcg ggattttttc ttccacggca
    19741 gttcgagcag ggtgtcgatg tagttgcgta cgacggtgga ttcggcagac atcggcggca
    19801 tcattttgag ttttttcagt tcggacaggc atttttcttc cgcttctttg ctcatccccg
    19861 cctttttgat gcctgcttcc aaggcatcca gttcgccgtt ttcgtcttct tcgcccaatt
    19921 ctttgtgtat cgctttaatc tgttcgttca gataatattc gcgctgggat ttttccattt
    19981 ggcgtttgac gcgtccgcgt atgcgttttt cggcctgcat aatgtcgagt tcggattcca
    20041 gctgtgccag caggaattcc atccgtttgc cgatttcggg aatttccaaa atctgttggc
    20101 gttgcgccag tttcaactgc aaatgcgctg cgaccgtatc ggttagccgg ctgttttcgg
    20161 caatgccgtt gatgctgccg ataatttcgg cggggatttt tttattgagt ttggcgtatt
    20221 gttcaaactg cgccaacagg gtgcggcgca cggcttcgag gtcggtattg ccgcccgtgt
    20281 cttcttccac gaccgcctct atatgggaaa cgaacagacc gcccgtgtct tcgatggtca
    20341 gaacacgtcc gcgatacaga ccttcgacca atacttttac cgtgccgtcc ggcagtttca
    20401 atacctgtaa gacttgtgcg acggtaccgg tctgatacag gtcggcggca accggttctt
    20461 ctagcgccgc atcggtttgt gccaatagga aaaccggttc ctcgcgggta atggcgtttt
    20521 ccagtgcggc gatggatttc ggcctgccga caaacagcgg cagaaccata tgcgggtaaa
    20581 cgacgacatc ccgcaaagga agggttgcca aggcggcata ttcctcaaaa tgcttttctt
    20641 tttgtgtcat aggtactctc ttgtgtctga cagattgccg attttcgcgt acattggggt
    20701 tgaaggtatt atttcaagca tatgtggttt atttatggag tttgatgcga tgccgtctga
    20761 aacattccgg cttcagactg catgggcttg gaaagacaag gcgggaacaa aaaactgttc
    20821 tgtgttgccg ctccttgctg taccatccgt atggtttacg gttctgccgc cctattttca
    20881 aaacatgacg caggtatccc atgtcttctt ttatttttcc cgataacggg gccgaatggc
    20941 gcaacgaaag tgtgcaaaag ccgcccaaag gttggcatta tgtccgcgaa agcggtgcag
    21001 acggcatttt gaaggctgcc tatcaaaata ttgcaactgt ctggcagggc gatttccaca
    21061 atgccaaaca ggtgctttct gcaatgaaga agagggctcg caaacctgcc gccgtccgtt
    21121 ccgatgcgga tatcgccgcc cttttccatg cccaccgtat gaagcaggcg cagcagagcc
    21181 gtattctgaa tatgcttgcc gttgaaatcc gccccggttt tgtgttggac aacaaacgcg
    21241 cgcccgatat acgcgccgcc ctgctcgacg tgtacggaga ggcggacggc aaaccgtttt
    21301 tcctgccgct caatctgctg ctggggttta tgggtgcgca cgagtggcat aagaaagggg
    21361 ttgccgttcc gcagctgggc ggcagcatac acgttccttt cggcgtattc tcgccgttgc
    21421 gcggcgaata cctcgacctg ctcgcccatg cgccgtcaac gggttttcag acggcattcg
    21481 atatcgggac gggctcgggc gtgcttgccg ccattttggc gaaacagggc attccttccg
    21541 tcatcggcac ggataccaat ccgaaagccg tcgcctgcgc ccgtgccaat attgcccgtt
    21601 tgggctttga aaaacaggtt gagatacggg aaaccgatct gtttcccgaa gggtttgccg
    21661 atctgattgt ctgcaatcca ccctggcttc ccgccaagcc gacttccgcc gtcgaatccg
    21721 cgttatacga ccccgaatct gcgatgctgg ctgcgttttt gcgggatgcg ccgaaacatc
    21781 tgaatcccga cggagaaatc cgcctgatca tttccgatct tgccgaacat ctgcacctgc
    21841 gtccgtccga ttttctggat aaggcatttg ctcaggcggg tttgcgcgtt gcggatgttt
    21901 tgaaaaccaa accggttcac aaaaaagctg ccgatccgaa caatccgctg gcttttgccc
    21961 gaaacaggga aactactttc ctgtaccgtt tgaaaaaggc ataaggggcg gcggtgcgct
    22021 tccggcggca ggcatcggaa cgcccgcgcc gccggcacgg catcattcgg gcggattatt
    22081 cttgtgaaaa tacccgctcg agcatactgc ccaatgccgt ctgacgcgtt ttgacggtgg
    22141 cggcagcttg ccggaaggct tcttccccgc cgaagaatac gaacttctct ctcgcgcggg
    22201 taatggcggt atataacagc tccttactca atccggacaa tgcatcgtcc ccttcgtccg
    22261 aaggtgcggc ggaaggcggc agcagccata cttcccggta ttccgaacct tggcttttgt
    22321 ggacggtcat ggcgaatgcg ggttcaaatt cgggcaggca gcttaccgct acctttttaa
    22381 atccgtccgc atcggcaaaa taggcggcaa ggctgccctg ccgtccgaca tcttccataa
    22441 tcagtccgat gtcgccgttg aacagttcaa gcgcgtagtc gttctgcctg atcataatcg
    22501 gctctccggc aaaatatgcc aaatgttccg gtatgttcat tttgcggcgt acatggcggc
    22561 aataggcttc gttgaagtct tccgcatcct gccgccaagc tgccagaacc acgatatccg
    22621 aaatgcccgc gtatgcggct tcgatattgc cgtcttttac cgcctgccaa taggctttgt
    22681 gtgcccggta caacctttcg actcgagcgt tcggactgca ttccgaatgt tccagttcgt
    22741 ccggaaaccg gtcaaacaat gcccacgccc cttcatcgcc cgatacggcg gcacgggcaa
    22801 ggcagccgat gccgctgttg tcgccgaagc ggtggctgaa cgacagatgg gcggtgtttt
    22861 gcgccaacac gggtggattt gcgctgacgc tgaaaccgtg ttccggaagg aagccggcca
    22921 gcctttggtg cgtttctccg tccaaaacgg ttttttgtga caaaacggac agcaccgccc
    22981 ctattccgac ggacgggagc tggttttcat cccccagcag aatcacgcgc gcgccggttt
    23041 tgaccgcttt taaaagttgc agcatcaatg ccgtatccag catagaggct tcatcgataa
    23101 ccaatacgtc aaacggcagc gggtaaacag ggttgaacgc cgcctgcatt ttgggcgggc
    23161 gcagcttcag cagtcggtgg acggtctgcc cttccagttt gagcaaatgg cggcggacgg
    23221 cctccggcgc gtcaaaaccg ttgattgcac ggtgcagcgc gcgcgccata tgtgccgccg
    23281 ctttgcccgt cggtgcggca agcgcgatgt tgggaagatt ttcgtcttca ccgcaaatca
    23341 gcgccagcag tttggcaacc gttgtcgttt tgcccgttcc cggcccgccg gtaatcacca
    23401 taaaagactg caacagtgcc aaggcggcgg catcgcgctg cccttcgctg cccgtgcctt
    23461 gaaaccattt tgcgaggttt tgcctcgcgc ctgccgcgtc gggggcggac gtgtcggctg
    23521 ccgccaagcg ttttatctcg gcagccaaat cgtattccaa ctgccacatc ctgcccaaaa
    23581 acagccttct gccttccaaa atcaaaggcg cggcggatgt tccgacaacg ggtgcgagtg
    23641 ccgacagcgc gtcagcctcg ccaccgctca aacggataaa cgaatgaccg ttttgcaatg
    23701 cctgaaacag gcgttcggtg cagtttgcaa gcacttcgtc gccggaaccc gcatagtgtt
    23761 ccaaaaaacg gattgccgcc cttgccgccg cttgggcaaa ttcatctgtc tgccgttcca
    23821 ttttattcct tatccaaatg ccgtctgaag gcgtggggct tcagacggcg cggtgttgtt
    23881 tcggctgttt aggcgtttgc gccctgtttg gggtgcaggc tgccgtcttt catgaccatc
    23941 acgcgctcga agcggccggc gagttcgtcg tcgtgcgtta cgaccaccag ccccgttccc
    24001 aattctgttt tcagttccag catcatatcc aaaacattcc tggcgttcgc acgatcgaga
    24061 ttgccggtcg gttcgtcggc aagcaggcat ttgggttggg taaccaaggc gcgtgcaatg
    24121 gcggcacgct gccgctcacc gcctgaaagt tcgcccgcgc ggtgcgtcga acggtgtttc
    24181 agtccgacct tttccagcat cgccattgcc gcctccgcag cctcttcacg gctttttttg
    24241 ccgatcagaa gcggcatcat tacgttttcc agtgccgaaa attcaggcag aagatggtgg
    24301 aactggtaca cgaaaccgag atggtggttg cgcaggatgc ccagttgtcg ctggcttaat
    24361 gtacgtaaat cctcgcccat cagcagcacc ctgccttcag acggcatatc cagcccgccc
    24421 aaaatatgca gcagcgtcga tttgccgctg cccgaagaac cgatgatgcc ggtgctttcc
    24481 cccgcgcgga tttccaaatc caagccgtgc agcaccagaa cgtccaaacc gccgtcccga
    24541 tagcgtttgc ccacgccttc gcatttcaaa atcaactcac tcataacgca aagcctccgc
    24601 cggttgggtt tttgacgcgc gccggctcgg gtagagcgtc gccacgaaag acagccccaa
    24661 ggaaatgcag gcaatcaggg caacgtcgcc catatcgaca tcgctgggca ggtagtcgat
    24721 aaaataaacc tgcgaattga tgaggtggac accgagcagg ttttcaaaaa acgccacgac
    24781 cctgccgacg ttccaaccca aaagcacgcc gcagaccaca cccgccaacg tgccgaaaaa
    24841 gcctgaaaac gcgccctgca ccataaaaat cttcatcacg ccgccagggg aaagacccaa
    24901 agtccgcaaa atcgcaatgt ccgcctgctt ttccgtaacc gccatcacca aggaagagac
    24961 aaggttgaac gccgccacgg cgataatcag cgtcaggatg atgaacatca tccgtttttc
    25021 caactcgacc gcctcaaaat agcttcgatt gctgaacgtc caatcgcgca cccaaaccgt
    25081 atccctttgc gcctccggaa tcagtgttgc cgtcaaggcg ggggcgtttt gcgggtcggc
    25141 gagtttcagc cgcagccccg caacttcctt atccaagcgg tacagtacgc gcgcgtcttg
    25201 gatatgcgtc atcgccaatg agttgtccac ttcgtaaacg cccgtcttaa ccagaccgac
    25261 cacggtaaac tgcttcaggc gcggcacgac tccggcaggg gtaacgttgc cctccggcgt
    25321 gatgacggta actttattgc cgacttccgc ccccaaagcc tccgccaagc cgacaccgag
    25381 gataatgtca aactcgcccg gaatcaggtc ttcaaatttg cctgccggca ttttgtcgcc
    25441 gtattccacc actttgcgct cttcagacgg caaaatgccg cgcatctgca cgcccctgat
    25501 ttcgcccgca ttggccagca atgcctgatt ggaaacatag ggcgcggcag ccaaaatacc
    25561 tttgcggttt tcggtaaacc gaagcaggtt gcgccaatcc gtatccgtat tgtcgatata
    25621 gccgatttcg gcgtgcggcg cgacattcag gagctgcccg cgtatttctt tctgaaagcc
    25681 gttcataacc gacaagacga caatcagcgc ggttacgccc aaggcgattc cggcaatcga
    25741 aaccatcgtg ataaacgaca taaagccgtt gcgctttttc gccctgagat acctcaagcc
    25801 tatccaagcc tctagagaaa acataacgct accttaaaaa tgtctgcaaa cgtgccgccc
    25861 cggacggcgg tttgggggcg gcggcaaaag tttattgtac cgtaaaaccc cggcagcgtc
    25921 cgaacgcccg agtgcggggg acggggcggc agagcgggcg gaaaacttgc acaacgcgtc
    25981 aaactgccct atcctttcct tcagaaaaac cgtttcttga ggaaaacaat gaatatccga
    26041 actgcttttg ctttgtgcgc catcgcctta tccgccgctg cggctgccta cgccaaagaa
    26101 atcaaaatcg atgccaacaa cacgccttat tccgaagccg acgcgcaaaa gctggcggta
    26161 acggcagtcg gtatgggtgt taaggaacct atcagcctga acggcggcag cgacagcatt
    26221 accgtgtccg gcagcagcgc gacgcagtgc gtgttcaaag tcggcaacgg aggcgcattg
    26281 cagattcaag ggctaaactg caagtaaacc gcccggaaaa atgccgtctg aaggcttcag
    26341 acggcatttt gcattggcgg cgttatgccc cgccttcttt aatcaggcgg cgttcgtaca
    26401 ccgcctgcgc cagcgttccc gcatcgacat attccaattc gccgcccaag ggaatgccct
    26461 gcgacagcct gctgactttg taaggcaggt ttttaaaaaa ctcggacagg acatacgccg
    26521 tcgcattgcc ttctgcggta aaagcggttg caataatgat ttcttcgact tccccgccgc
    26581 ccagccgttg cgccagcctg tccaatgcga tggcggatac gtccattccc aatgccgtat
    26641 tgatttgccc catcaggacg aaatacagcc cgtcgtggca gtttgccgct tccatattcg
    26701 acacgtcggc aggcatatgc accaccatca gccgccgccc gtcgcgtgtt tcatcggcac
    26761 aaatatcgca caatccgcct tcgcaaaacg tgttgcacat cgcgcaatgg taaacctgct
    26821 tcaatgccgt ctgcaaggca tccaccagtt tttcagcctc tttgcgcttg tgttggagca
    26881 aatgatacgc tatccgctgt gccgatttcg gcccgacgtt gggtaaaacc ttcagcgcgt
    26941 cgatcaatcc ttggaaggca tcttgttttt tgtggctcat catattccgc cgtatgggaa
    27001 aacggccgga atattccgac cgttatgttg tcaacaaaag tgtcaattac tgaccgtcgc
    27061 cgttgtcgac cgattgcgct cctttggtct gtttgatttt gccgttgaaa taacgtatca
    27121 acaagtcgaa ggtattggca gactgctgct gcgccaaagc ctgttttgca agcgggatgc
    27181 gcgcggcggc atcatccggc ggggttacag cctgtacttc gacaatcacg ggtgccggca
    27241 ggccggtcag cctgacatag gcgggtttgc cgtttgccgg ttttactttc agcagttccg
    27301 cataagcctc gggcggcatg gactgccttg cctgctgtgc gcccaaaacg gacacttccg
    27361 accatttcac gtcaactgcc ttgccgccgt tcagttgggt aagcacgtct tttgccttgt
    27421 tttcggcaag tttggcggct tcggtacgga tataagcctg acgtaccgcg tctttggctt
    27481 cggcaaacgg cagggttttc tcttcgcgga cttctttggc gcggacgacc cacgcggttt
    27541 cgctgttgat ggtcagcact tcggaattgt gttttttctt caatacgtcg tcgctgaata
    27601 cggcattgat caggttttcg ggcataccgg acatttgcgc atcctgcctg ctcagccaag
    27661 tttcttgggt ttcgactttc aaaccgctgt ttttggcggc ttcggcaagc gaggaaggat
    27721 ggttgaacgc gtcatcgccc agcttttctt ttgccttatt gaagtcggca accgcctttt
    27781 tcattttcaa ttcgttttct acggcggctt tttcctgctc gaaagaaggt ttggcttcat
    27841 ttgccggcaa acgcgccacg cgctcttcaa acgcattttt cacttctgtt tcgctgacgg
    27901 tctgtttgtc tgcaaagtct ttcagattca aggcgacata ttccaatttg accgctttgg
    27961 gaagcaggta gtcttttttg tttgcgttat aaaacttctg caaatcggct tcagacactt
    28021 tgacttgggc gatgaattcg tcggggttga aagtgtgcga acggatggtg cggttgacct
    28081 gcgtcagcct gatcagctgt tccgcctgcg cgtcgccgac caatacgccg ttttggacga
    28141 ggtttaccaa attctgcaag gcaaactgat cgcggatttc ttcgacaaac tggtcttcag
    28201 acatatggcg ttgcgacagg tagcggttta aaagcgcgtg gtcgaatttg ccgtttgcgt
    28261 cgtggaaatt gggatcatcc acgataatct gcttgatttg ttcggaagaa accgaaatgc
    28321 ccatcagctt cgcgccctgt ttcaggtagg cgcgttgcag cagggattgg aacaccgcgt
    28381 cgcgcgaagg gccgccgccg tccgcctgtt cgttctgtat ggcgttgttg atggagtggt
    28441 cgctgatttt ttcgtcgccc acttggacga tgtagtcggc acccggatgg gataccgtgc
    28501 tgaccccgaa gccgacgaag gttaatgcaa tcaggcccaa aaggacttgg gcgggcgttc
    28561 tgtatttttc gatggaatgg aacatatttt aaatcgggat atagaatggg aacgggaaat
    28621 tcaagtcggg tattgtaacg gtttttatcc ctgtctgcac ggggcttgcc ggttgaagat
    28681 gccgtcgtag gtttcttcgc tgaagccggc gtaaaccttg ccgccgcact ccaatacggg
    28741 acgcttgatc aggctcggca tttcggacat cagtttgacg gcctccgctg tcgagaacag
    28801 ggctttttgc tgtgtttcgg catcgagttt gcgccagctt gtcccgcgtt tgttgagcag
    28861 ggttgccaaa ggcacttgtt ccagccacga gcagatttcc gcttcggaag gcacctgttt
    28921 tttaaaatcc cgaaattcaa actccaagcc gtatccggca agccggtttt tggctttttt
    28981 gaccgtatcg caatttggga tgccgtgaag gactatcatt tggaaacctt ttgtctgaaa
    29041 taataaaacg gatattttac tataagtgtc tgaaaatttg cccgtctgtt tcagacggca
    29101 gggcggttat gttacaatcc gaaaattcga aaaatttaat ctcttgttca ataaaggctt
    29161 taccaatcat gatttctacc aacggcatca ccatgcagtt cggcgcgaag ccgctgtttg
    29221 aaaacgtatc cgttaaattc ggcgaaggca accgctacgg tttgatcggc gcgaacggct
    29281 caggcaaatc caccttcatg aaaatcctcg gcggcgattt ggaacagacg gccggcgaag
    29341 tggcgattga aaacggcgtg cgtttgggta aattgcgcca agaccagttt gcctacgaag
    29401 acatgcgcgt gctggacgtg gtgatgatgg ggcataccga aatgtgggcg gcgatgaccg
    29461 aacgtgatgc gatttacgcc aatcccgaag ccaccgaaga cgactacatg aaagccgccg
    29521 aactggaagc caagttcgcc gaatacgacg gctacaccgc cgaagcgcgt gccgccgaac
    29581 tgttgagcgg cgtgggcatt tccgaagatt tgcacaatgc gaaaatggcg gaagtcgccc
    29641 cgggcttcaa actgcgcgta ttgctggcgc aggcgctgtt ctccaagccg gatgtattgc
    29701 tcttggacga accgaccaat aacttggaca ttaataccat ccgctggttg gaaggcgtgt
    29761 tgaaccaata cgactccacg atgattatca tcagccacga ccgccacttt ttgaacgaag
    29821 tctgcactca catggcggat ttggactaca acaccatcac catctatccg ggcaactacg
    29881 acgactacat gctcgcctcc gcccaatcgc gcgaacgcgc cctgaaagac aatgccaaag
    29941 ccaaagagaa actgcaagag ctgcaagagt tcgtcgcccg cttctctgcc aacaaatcca
    30001 aagcccgtca ggcaaccagc cgtctgaaac aggccgacaa aatcaaatcg gagatggtcg
    30061 aagtcaaacc ttccacccgt caaaacccgt atatccgttt tgaagccgat gaaaaagcca
    30121 agctgcaccg tcaggctgtg gaagttgaaa aactggcgaa acgctttgaa acccagttgt
    30181 ttaaaaacct gaacttcatc cttgaagcgg gacaacgcct cgccatcatc ggcccgaacg
    30241 gcgcgggcaa atccaccctg ctgaaactct tggccggcgc gtacaacccc gaatattcag
    30301 acggcctgtt accggacgaa ggcaccatca aatgggcgga aaaagccagt gtcggctact
    30361 atccgcaaga ccatgaaaac gacttcgacg tcgatatgga cctgagcgaa tggatgcgcc
    30421 aatgggggca ggaaggcgac gacgaacaag tcatccgcgg cactttgggg cgtttgctct
    30481 tcggcagtaa cgatgtcgtg aaaaaagtga aggttctctc cggtggtgaa aaaggccgta
    30541 tgctttacgg caaactgttg ctgttgaaac ccaatgtctt agtcatggac gaaccgacca
    30601 accatatgga catggaaagc atcgaatcct tgaacatggc actggaaaaa tacaacggca
    30661 cgctgatttt tgtctcccac gaccgtcagt tcgtttcctc cttggcaacc caaatcatcg
    30721 aactggacgg caaaggcgga tatgaacact acttgggcga ttacgaaagt tacttggaga
    30781 aaaaaggcgt agcataaccg ccggttggaa caatgccgtc tgaagccgct tcagacggca
    30841 ttgttgataa ctttaaaata ggaagcatat gcagacttac ctcgtcggcg gcgccgtccg
    30901 cgattatctt ttgggcttgc ccgtcaaaga ccgcgattgg gtggtcgtcg gcgcagacgc
    30961 acaaaccatg ctggcgcaag gcttccagcc ggtcggcaaa gattttcccg tgtttctcca
    31021 tcccgaaacg cacgaagaat acgccctcgc ccgcaccgag cgcaaaaccg ccaaaggtta
    31081 cgtcggtttc agtttccacg ccgacaaaga cgttacgctg gagcaggact tgatgcgccg
    31141 cgacctgacc atcaacgcga tggcgcaaga tgcggacggc aagattatcg accctttcgg
    31201 cggacaacgg gatttggcgg caggcatttt gcgccacgtt tccccggcct tcgccgaaga
    31261 ccccgtccgc atcctgcgta ctgcccgctt tgccgcgcgt tacaggtttg aaatcgccga
    31321 agaaaccata aagctgatgc ggcagatggt ggaaaacggc gaagcggacg cattggttgc
    31381 cgaacgcgtc tggcaggagt ttgcgaaagg tttgatggaa aaaaatccgc gcaaaatgat
    31441 tgaagtgttg cgcgaatgcg gcgcgctcaa agtcttgctg cccgaagtca atgccctctt
    31501 cggcgtgccg caacgcgccg actaccatcc cgaaatcgac agcggcatcc ataccctgat
    31561 gacgctgcaa cgcgccgccg atatgggttt gagcctgccc gaacgctatg ccgccctgct
    31621 gcacgacttg ggcaaagcca aaacaccgtc cgacatcctg ccgcgccacc acggacacga
    31681 cctcgccggt gtcgaacccg tgcgcgaagt caatcagcgg ctgcgtgcgc cgaaacattg
    31741 cgccgagctt gccgaacttg tctgccgttg gcacatcatc ttccatcagg ttgaaaaact
    31801 ccgcagcaaa accattatcg acgtattgaa aaaaaccgat gccttccgcc gcccagaacg
    31861 ttttcagacg gcattgaacg tctgcattgc cgacacgcaa ggccgtctga accgcgaaca
    31921 cacgccctac ccgcaacgcg cgcactggct cgccttactc gaagccgcca atcaggcgga
    31981 ttcgggcaaa atcgccgccg aatgccgcgc gcagggaaaa gcgcacctta tcgccgaaca
    32041 aatcgaccgg gcgcggctgg cacaaatcgc cccattgcaa aaagcgtttc gagcggcgca
    32101 agacaaaaca gaaaaacatt aaaacgtcca atgcagccac ttttatagtg gattaacaaa
    32161 aatcaggaca aggcgacgaa gccgcagaca gtacagatag tacggcaagg cgaggcaacg
    32221 ctgtactggt ttttgttaat ccactataaa gttttgagga cgatacccaa tccaagcttt
    32281 gcaacagccg ccgccatatc cgctataatt cacgcttcag ccattccgcc cccgacataa
    32341 aatcatgacc ctgaaaaccg atttattgcc taaaatcaac aacgaagatt atcaacgcct
    32401 catcctcaaa cacagtgcgg aatttagcgg tggcgaaatc cgcctgttga acgaaatcct
    32461 cgaaaaattc aatttcgacg ttgttcaggc gcaggcattg gcgcaagccg tcatgcagca
    32521 aatccgcttc gaccccaacg cctaccacat cgacagcgac gacgaagaca ccaccggcat
    32581 ctgcccccac tgcatcaacc cgcctatgcc acccctgcgc gactatctcg tttggcgcga
    32641 aacccgcgga taaaacgctt ttgaccgtta tcttttcaat gccgtctgaa acgccgccga
    32701 ccgttcggac ggcatacccg acaaagggaa cactatgctg caaaccgaca acctgaccgc
    32761 cgcgcaaccg caacgcatcg ttgccgccca aaccgcctcc gcacaggaag aactgctcga
    32821 acgcgccctc cgccccaaaa cgctggacga ctacatcggg caagacaaag ccaaagaaca
    32881 gcttgccatt ttcatccaag ccgccaaaaa acgcggcgaa gcactcgacc acgttttgct
    32941 cttcggcccg cccggactgg gcaaaaccac actggcgcac atcatcgcca aagaattggg
    33001 cgtaaatttg cgccaaacca gcggccccgt cctcgaacgc gcaggcgacc tcgccgccct
    33061 tttgaccaac cttgatccgc acgatgtatt gttcatcgac gaaatccacc gcctcagccc
    33121 tgttgtcgaa gaaatcctct atcccgcgct cgaagactac cggctcgaca ttatgatagg
    33181 cgaaggaccc gccgcccgtt ccgtcaaaat cgacctgccg cccttcacgc tcatcggcgc
    33241 gaccacccgc gccggtatgc tgaccaatcc gttgcgcgac cgcttcggca tcgtctcccg
    33301 ccttgagttt tacgaaaacc gagaccttac caccatcgtc agccgttcgg cacaactgtt
    33361 gcagctcgat atgtccgaag aaggcgcgga agaaatcgcc aaacgcagcc gcggtacgcc
    33421 gcgcatcgcc aaccgcctgt tgcgacgcgt gcgcgatttc gccgacgtga aaaacaacgg
    33481 cacaatcgac ggcggcatcg ccgatgccgc tttaagtatg ctggacgtgg acgcgcaggg
    33541 gctggacgtg atggacagga aatttctcga agccgttttg cacaaattcg gcggcggccc
    33601 ggtcggtttg gacaatgttg ccgccgccat cggcgaatct acagacacca tcgaagacgt
    33661 tatcgaaccc taccttatcc aacaaggctt cctgcaacgc accccgcgcg gcaggatggc
    33721 gaccgaacgc gcctacctgc atttcgggct gcccgtcgaa aaataacgca atgccgtctg
    33781 aaacagagct aattttcaga cggcatttct atttcaatca ttggcgcaag gttcagcctg
    33841 ccgctttttt ccagttccgc cctcatcgca tcaatcaccg ccttatagtc tggtttgccg
    33901 aaaatcgcag aaccggcaac aaaggtatcc gcgccggctt gggcggcggc ggcgatattg
    33961 tcggttttga tgccgccgtc cacttcaatg gcaatacgtc tgccgctttt ctcttcatag
    34021 cggtcaagca tggcacgaac ctgtctgatt ttttccaaag tatacggaat gaagctctga
    34081 ccgccgaacc cggggtttac cgacatcagc aaaaccatat ccagcctgtc caatacgttt
    34141 tccaacagat atacgggcgt tgccggattc aacaccagcc ccgcctgaca gcccatgtcc
    34201 cgaatcaggc tcaagctgcg gtcaatatgg cggctcgctt cgggatggaa cgtgatgatt
    34261 gatgctcctg ctttggcaaa cgactgaatc aggtcatcca cgggttcgac catcagatgc
    34321 acatcgatcg gcacgcttgc ataaggcttc aacgccgcgc aaaccatagg cccgaaggtc
    34381 aggttcggca cataatggtt gtccatcacg tcaaaatgga tcagatctgc acctgccgca
    34441 atgacgcttt ccacctcttc gccaagccgt gcaaaatctg ccgataaaat gctgggtgcg
    34501 atacggtaag tagtcatgtt tttttccttc aatatccttt tatagtggat taacaaaaat
    34561 caggacaagg cgacgaagcc gcagacagta cagatagtac ggaaccgatt cacttggtgc
    34621 ttcagcacct tagagaatcg ttctctttga gctaaggcga ggcaacgctg tactggtttt
    34681 tgttaatcca ctatacgttc cgattccgcc gttatgtctg cctgccggac atacgtacgc
    34741 attattaaca aaagttaacc gcgataatac catctttcac acgtcaatct agtatatttc
    34801 ctaaaatttc caacaagagg aaaagccgtg ccactgcctg ctccctgccg ttttgccaaa
    34861 cctgccgcct cttttttaag tatggctttg ctttcctgcc agctttccca cgccgccacg
    34921 gcttatatcc ccctgaacga ttttcaaccg aactgcgaca tacgccggct cggactgaca
    34981 cagggtcagc acaatgaact gcgtaaaatc cgcgccgcct tcaaaatggc gggcgacagg
    35041 gcgcgtttga aggttatgca ttccgaacac agccgccgcc ggtctgtcgt cgaaatcatt
    35101 tcttcggatg tttttaatcg gaacgaggcg cgcgattatg tcgaaagccg ctatttgtcc
    35161 ggtatggatt ttgcggtgga cgaattggaa atccaacacc gcttcttcca tatcctcaca
    35221 ccgcaacagc agcaaatgtg gctttcttcc tgcctcaaat aatccccgaa acgctcacgg
    35281 cgcacgttgc tccggcagcc tgcccgccca gtcgcaggca aactgccacg cggaacgtcc
    35341 cgaacggctg ccccgcgtct gcgcccactg caatgccgcc atctgtgcgg tttcatcata
    35401 cggcacgccg aaatcttcca gccaattttg caccgccgcc agataatcgt tttgatcgaa
    35461 cggataaaaa ctgagccaca atccgaatcg gtcggacagg gatatttttt cttccaccgc
    35521 ttctttctga tggacttccc ccccgcatcc ccgtcgtacc ggcattctcg tcaaaatatt
    35581 cgggcatcag gtgccgtctg ttggaagtcg cgtaaaccaa aacgttggcg caacgttgag
    35641 acagaccgcc gtctaacgcg gttttcaatg ccttataggt ttcatcgccg ctttcaaacg
    35701 acaaatcgtc gcaaaatacg ataaattttt ccggacgttc cttcaaaagc gtcaacaggt
    35761 aaggcaggcc gattaaatcg cttttatcga cttcgatcag gcgcaatccc ttattcgcat
    35821 attcgtgtag cagggctttg accagcgagg atttgcctgt tccgcgcgcg ccgctcatca
    35881 atacgttatt cgcgggtctg ccgacaatga actgttcggt attacgcacc agcaattcgg
    35941 tttgcctgcc gactcccgcc agccttacca agggaaaggt gtgcggatcg ggcaagtgtt
    36001 ccaaaaaacc ttttttgccc gcactctgcc agcggaaggc aagcgcgttc caatccgtat
    36061 gcccgggttc gggcggaagc acggcatcca aacgccgcaa aacggcatag gctttatcga
    36121 gaaattcgtt caattccatc tctacctcac tttgcatatc tttgcgccat cagccgttcg
    36181 acggtgtcga cgattgcctg cgtattcgga tcgatttcga tgttgatcct gtcgccgacc
    36241 tttctgctgc cgaacagcgt ccgttccaaa gtttcgggaa tcagatggac attgaaacgg
    36301 ccgtcttcga ctttgcctat ggtcaggctg caaccgtcca agccgacgaa ccctttggtc
    36361 aggatatagg gtttgagttc atgcgggagc gaaaaccaaa ccgtgcggtt gaacccgtcc
    36421 cgttcgattt cgacaatagg cacggttgcc ataatgtgtc cgctcatgac gtgtccgccg
    36481 atttcgtctc cgaaacgcgc cgcccgttcg atgttgacgc aatcgccttc cttcagcagc
    36541 cccaaattgc tttttgccaa agtttccgcc attaaatcga agctgacgcg gtttccttcg
    36601 atttcggtaa tcgtcaggca gcagccgtta ttggcaaccg atgcgccgcg ttgcagattg
    36661 tccgccgcct cttgcggaag ctcgacgaca taagtctgaa atgcctccga cgggcggtgg
    36721 attgccgtca gttttcccaa tccttgaaca atgcctgtaa acataatcct gtttccctgt
    36781 gtcggtaaaa atggtgcaaa ttgtagcatc tccccgcgaa aaatgccgtc tgaaatgcct
    36841 tcagacagca ttatgcctcc gattcgggca aaaaccgccc ggtatggctt gacctttcct
    36901 ttccacgccg gtcggcggtc ttgcccttat ccctcctgca aatcgatttg cgtgttcaag
    36961 tcggcaaaat gcccgtcaaa ctcgaatctg accgaccgcg ccctttgctg ctgcaaccag
    37021 cttcttaatg ttttcatacc cgaaaacaga tagggaatcg cgctttgcag aatctgcggg
    37081 cggatataca taatgttgta gtgcatcgtt atcggcgttt ccacataata cgcattgcac
    37141 aacggtgtgc gtttcgacac ggtttcaaac ctcgccacca aatcgcccag cagatacggc
    37201 atatcgcacg gcacaaccaa aagccagtcg gcagtcgcca actgcaaatc gttggctgcg
    37261 gtacacaatg ccgaaagcgg gccgaaatgc tgccactgcc gtgcgtccgg aaaaatatgc
    37321 ggacttcttc gagcatattc ttccaaattc cggttggtgc tgatggcgat atggctgacc
    37381 tgcggcctga ccctgtcgat gacatgatct atcagtgcct taccccccaa aagagcaagc
    37441 cctttgtcct cgcctcccat acggctcgcc tgaccgccgg ccagtatcag ggcaaaagtt
    37501 ttcattgcgg atgttctctt ggaaaagttc gaggttttca tgattgcagt ctgccgttcc
    37561 caatgactca aaatgccgtc tgaagcagac ggcaaataaa ttcatattat ctgaatttta
    37621 tcataacatg atttaacact gaagcggtgc ggattaagtt ttccttaacc aattctttct
    37681 gagcagttgt atctaattcc aaagaatgat attgtttgca ttatttagaa caatttttcg
    37741 ccgagcatga tactgccagc ccgtttttca gacggcatca gcctttccct gcgcctgaaa
    37801 ctcctgaccg gactgtgggt cgggttggcg gcattgtctg tcgttttgac actgctgctc
    37861 tctttgcgtc tggaaaacgc ggcctccgtc atcgaagagg cgggcaactt gagaatgcag
    37921 gcataccgtc tggcatacat ggcgggtgaa ggctcgcccc gtgcgcaaat tgacaatcag
    37981 gttgccgaat ttgaaaaaag tttaaaacgc attgcccaaa gcgatgccat ccatccgctg
    38041 attccttcgg acacccctct tgcttatgat ttgatacaat ccatgctgat tatagattgg
    38101 caggcacaca tcctcccccc gctccagtcc taccggcgac cgactcaggt cgatctctac
    38161 cgctttgccg gaaacatcga actgtttttg caggcattgg aaaatgccaa cgaaaaaaac
    38221 acatggtggc tcaggcgttt tcaatgggca attatgttga tgacgctggt gtcgtctgta
    38281 ctgatgctgt tttggcacca gatttgggtt atccggccgc tgcaggcgtt aagggaaggt
    38341 gcggaacgca tcggacggag gtgtttcgat attccggttc ccgaaggcgg tacgccggaa
    38401 ttcaaacagg tcgggcgttg tttcaatcaa atgggcggca ggttgaaaat tttatatgat
    38461 gatttggaag gacaagtcgc cgagcagaca cgcagtctcg aaaaacaaaa tcaaaacctg
    38521 accctgctgt accaaactac acgggacctg caccaatcct acataccgca acaggctgca
    38581 gaacattttc taaaccgtat cctgcccgcc gtaggagcag attccggcag agtttgtttg
    38641 gacggcggat ccgatgttta tgtttccatt catcatgcgg attgcggcac agcagcttcg
    38701 gatttgggga agtaccatga ggaaatcttc cccattgagt accagaacga aacattgggc
    38761 aggctgttgc tcagctttcc aaacggcatt tctcttgatg aagacgaccg catcctgctt
    38821 caaacactag gcaggcaatt gggcgtatcg cttgccggcg caaaacagga ggaagaaaaa
    38881 cgcctgcttg cagtattgca ggaacgcaac ctgattgcgc aaggattaca tgacagcatc
    38941 gcacaagcat taacgttcct aaacctacag gtacagatgc tggaaaccgc ctttgccgaa
    39001 aacaaacggg aggaagccgc agaaaacatc ggcttcatca aaacaggcgt gcaggaatgt
    39061 tatgaagatg tccgcgaact gctgctcaac ttccgtacca aaatcagcaa taaagaattt
    39121 cccgaagccg ttgccgacct attcgcccgc tttacgcaac aaaccgggat aacggtcgaa
    39181 accgcctggg aaaacggttc gttcctgccg cctcaggaag cgcagctcca aatgattttt
    39241 atcctgcagg aaagcctgtc caacatccgc aaacacgccc gcgccaccca tgtaaaattc
    39301 accctttccg aacacggcgg acgctttacc atgaccatcc aagacaacgg acaaggtttc
    39361 gacacggaga aaataggaga acctacgggc agccatgtcg gactgcacat catgcaggag
    39421 cgtgccaagc gcatccatgc cgttttagaa atccgttccc aaccccaaca gggaaccacc
    39481 gtctcattga cgggtgcatc tgaagaaagc ttgaaatgac cattaaaatt attctgatag
    39541 acgaccacac cctcttccgc agcggcatta aagccctttt gtcgcgccaa cacggttttg
    39601 aagtcatcgg cgaagccgca gacggcctct cgggcatcaa aatgattagt cggctgcaac
    39661 ccgatgtcgt cctgctcgat ttggatatgc ccggcatgaa cggacgcgaa gcactctccc
    39721 aaatcatcag catcaatccg cagcaggcag tgattatgct gaccgtttcc gaagacagcg
    39781 acgacttgac cgaatgtatt cgcatcggcg cgcgcggtta cctgctgaaa aacatcaacg
    39841 ctgactttct gctcgaaagc atacgcaaag ccgccgaagg cgataatgta ttctcgcccg
    39901 agatgaccgc caaactcgtt aaaagcctga tttcccccca acctgcccaa gggacacagg
    39961 cactctcctc acttacccct cgcgaactgg aaatcttggg ctatctcgcc gcagggcaca
    40021 gcaacaaaat catcgcccgc cacctcgatc ttgccgaatc caccgtcaaa gtccacgttc
    40081 aaaacctgct ccgcaaactc aacctcagca gccgggtgca ggccgctgtt tacgccatcc
    40141 ggcacaacgt cccccaaccc atgctggaat aaggcgggtt cagacggcat attaggggtt
    40201 ttaatccccg tacggtcatt cggataacag accaagcatg taagtttatg cccccataag
    40261 tacgcttggc atagcagtaa tattgttcgg ttcagtgttt tccgtttgcc cctatctgat
    40321 actgcaatat cagctatgcc gtctgaaaac gcatcatcat gatattttca gacggcataa
    40381 taaaaagcgg aaatactaat gcagggtaaa atgttccatt ccgaatccca taaatataca
    40441 atggcttata tcgtttaagc atgtgtaacc caccctcata tcaatcaata tatagtggat
    40501 taacaaaaac cagtacggcg ttgcctcgcc ttgccgtact atctgtactg tctgcggctt
    40561 cgtcgccttg tcctgatttt tgttaatcca ctataaaaat gccgtccaaa cccatgtttg
    40621 agacggcatt tcgctataga agcaatcagg caacctgggt ttgatgctcg tctccctgac
    40681 gctcacggat caaacctaaa cggtaaactg tttcaccttg ttcacccaag agaccctgaa
    40741 ccgcatcggc atcttcggca gcaacaataa cgaccatgcc gatgccgcag ttaaaggttc
    40801 ggtacatttc ttgggtttcc acattgcccg ccttttgaag ccattggaag agcttgggca
    40861 attcccacga tttagcatcg atttgtgcaa ccgtgttttc aggcaacacg cgcggcacgt
    40921 tttcggtaat gccgccgccg gtaatgtgtg ccataccttt aatggtaaat ttttccaaag
    40981 cggcaagaat cggtttcaca tacagacggg tcggcgcaat aacagcctca cgcaaggttt
    41041 tgccattatc aaactcggca tccaaatcgg gattgtcgcg ttcgatgatt ttacggataa
    41101 gggaatagcc gtttgaatgt gcgccgttgg aagccaaacc caataccaca tcgcccgcgc
    41161 cgatgctgcg gccggtaatg acattctctt tttccactac gccgacggca aaacccgcca
    41221 aatcgtattc tccgacggga tacatacccg gcatttcggc agtttccccg ccaatcaggg
    41281 cgcagccgga ttcttcgcaa ccttgtgcaa tgcctttgat gacatcggtt gcgcgcggaa
    41341 catccaattt gccgcaggcg aaataatcca agaaaaacag aggttctgct ccttgaacca
    41401 aaatatcgtt gacactcatt gcaacaaggt cgatgcccac cgtatcgtgt ttatcccaat
    41461 cgaaggcaag tttgagcttg gtacccacgc cgtccgtacc gctgaccaat acgggatttt
    41521 tatatttctt gccgatttcg accaatgcgc caaaaccgcc caaatccccc aatacttccg
    41581 gacgcatggt gcgtttggca aacggtttga tgttttcgac cagttggtcg cctgcgtcga
    41641 tatcgacacc tgcatcgcgg taactcaatg aagtactcat cgtttttcct tggtaaatgg
    41701 ggattggacg gtaaaataac ggggcgtatt ctaccttatt tcacgtttgc aggttcagat
    41761 ttttagacaa tattgtaaac agtccgccat atacccgcgc gtgtcgggtt tggcgggacc
    41821 gtccgcagga ttaacgggca gaaacccgcc tgcccttccc ctcaattcct tatatatcgc
    41881 gttccatcaa aagacgcatt gcttttctta accattcctt ttggcagacg agcggaaggg
    41941 gttttttgat gccatcatca aaatcaatat tttcttcttt ccggttgaaa ccccggcatt
    42001 aggggcggtg aatctgattg cgggcggaag cacccgtttc cgattcggtg cggaacaaat
    42061 ggcggcactt tatgtaccgt tctgcgtgtt gaaacatata ggcagataaa aaagccgccc
    42121 gctgaaaagc agacgactta tgttttgtgg cactaatttg tcccgataag cattaactat
    42181 ataatttatt tatcattatt ggtgcggacg gagagactcg aactctcaca cctctcggcg
    42241 ccagaaccta aatctggtgc gtctaccaat ttcgccacgt ccgcatggga attgggcgat
    42301 tatacagatt ttgttttttt gtgcaaggtt ttcggcgggg ctgttgatgg cttggggttt
    42361 ggggcggtaa aatctgtttt tcgtccgcct gacatcggaa tcgggcggtt ttttgttttt
    42421 attgacggaa tttgggtatg cctgctgctt tgattaagga ttttctgctg actcagggtt
    42481 tgaagctgcc gcttgacgag gttcgggcgg cgtatctgac ggcgcagacg gtaatgggta
    42541 tggggacggc ttcgatagac cgttcggttt tgtggcgcag tgatgagggt tggaaacttg
    42601 ccgattacct gtcgtgcgac aatgtccgcg aagatgcact gaaacggctt ttcatggctt
    42661 tggattcggt gttttcgcgc tcgacaggcg tgcggagtgc ggcggtctat gccttgatgc
    42721 cgtctgaaaa ccaggctttc caactgatat gcctgtccca acagggagaa ggtttggaaa
    42781 acatatggaa tctagatgaa aatgttgccg atgtttcact tgcctgccgt tgcgcgcaaa
    42841 gcggctggat gaatgttgcc tcggatgtac gccgttggtt ggatttgggg gagctttcgg
    42901 gagaacgcaa tcatgcttcg gcggcgcaaa tttccattcc aatctgcacg gaaagtggcg
    42961 gtgtgttggg cgtggttcat gtggaatttg aatgcgcaga gtgtgcggat gaggcagcgc
    43021 aggcggaatg ggtggctctt gccttggctt tgtccgaacc tttgaagcag cttttgggca
    43081 tcactgccgc agaaggagat gaaaatgtct gaattattaa actatgttgc ttcctgccgc
    43141 ctgccgaccg aatggggcgt atttacgatg cacggctttg aagaggcaaa cgggcaggaa
    43201 cacgtcgcgc tgaccgtcgg tgatttttca gacggcaatc cggttctgac gcgcatccac
    43261 tccgaatgcc tgacgggcga tgcgctgttc tcgagaaaat gcgactgcgg acctcaactt
    43321 gaagcggcca tgagggcggt acagacagag gggcgcggca tcatcgtcta tctgcgtcag
    43381 gaaggacgcg gcatcgggct gattaacaaa atccgcgcct atcatctgca agaccaaggt
    43441 atggatacgg ttgaagccaa tttggcactc gggctgcccg tcgatgcccg cgatttccgt
    43501 ttggcgcaat ctatctacga atatctgggc atccgctcgg tcaaactgct gaccaacaac
    43561 cccgaaaaaa tccaaaccct gaaagatgcg gggattaacg tggtcgaacg catccccctg
    43621 cacgtcgggg aaaaccttga aaacaaacgc tacctccaaa ccaaagcaga caagctggga
    43681 catctgatgt cggaataagg caaagttgca gggaacgggc atcctgcgcc gcctttcggg
    43741 aaacaggttt ccataccttg ataaagcaat aagttttata gtggattaac aaaaaccagt
    43801 acagcgttgc ctcgccttag ctcaaagaga acgattctct aaggtgctga agcaccaagt
    43861 gaatcggttc cgtactattt gtactgtctg cggcttcgtc gccttgtcct gatttttgtt
    43921 aatccactat ataaagttac agggtgcgga tgcaaacgca ttgcgagcgc gggtttgagg
    43981 catacgcgca aacatcttaa tataatggat tgatatttat gattttctcc atcatcgtcc
    44041 ctatttacaa tgtggaaaaa tacctccgct gctgcgtgga ttccgtgctt gccgaaaatt
    44101 ttgccgatta tgaaatgatt ttggtcgatg acggttcgcc ggacggctgc gggaagattt
    44161 gcgacgaata tgcaggcaaa tatccgcata taaaagtgat tcatcaagaa aacggcgggc
    44221 tgtcggatgc ccgcaacgcc ggtatccggg cggcaaaagg cgattaccta atctttttgg
    44281 acagcgacga ctattgggcc gataccaacc gttcaaaaaa cgcggggggg gggattctct
    44341 ttgatttaca acaacttgca gacaaaaagg ttgatttgat cctgcatccc tcgtccctca
    44401 attaccacgt catccccaaa ggggcggact tttcggataa tgattttgtc cgccattttg
    44461 aaacgctggt ggaggggcgg tactatatcg ccaacgcgtg gacaaaaatc gtcaggcggg
    44521 aaataatcat caaaaacaat ctgtttttcc caaaaggata cattcacgag gatttcccgt
    44581 acagtttgca attggcgcgt tttatcaaga cttttgcctt ttacgataac cctttttacc
    44641 agtaccgcgt tctcggcggc tctatcagcc acaacatcaa atacaaaaat ttcagcgatg
    44701 tgctgacgca tctcgaccgg ggtgtggatt ttttagtcga aaacaaaaat tcccccatct
    44761 acggcggttt gcaaaaattt gtcttcgaca atatcggcta tctgaggtct atattggtaa
    44821 ggctttattt ttccaaaaac attatcctca tctaccggaa atatttttca tttaaagaaa
    44881 aatgcagaaa gatattcggc gcgaagacaa tccgtccggt ttttatcggg aagaccgcat
    44941 tcatcatagg attgccgata ttgcgcctgc tcgtaccgcc tatgctgtac ccggcaatca
    45001 aggccgttta tcagaaattt ttttcggaat aagcttccgg caaaccccaa atcagaagtg
    45061 cgcgggaagt tgggacaaac agcccccggc cggcaaggat tgcggcaatg ccgtctgaag
    45121 ccacgaatcc ggcttcagac ggcatctgtt taccaaaaag caaataattc ggtttggcga
    45181 aaaaaacaga tttgcttttt ggtaaatacg cgattacaat ccgctacatc cgatttctac
    45241 aaaggatgaa acgatgaccg acacagccgg tctgcgccgc cgcaacctgc ggcaatggat
    45301 agcagaacac tacggcggtt tgcaaacccg ttttgccgaa gccgttgccc tcaacacagg
    45361 cgaactctcc gcccttttga aaaacaaatc cttcggcgag aaaaaagccc gtaaaatcga
    45421 acaggcggca aaaatgcccg ccttctggct cgataccgaa cacaccgccc gcccgcccga
    45481 acacacagga aaacacacca tgtcccatat ttcccccatc cccgaaatcc tagccgacat
    45541 caaagccggc aaaatggtca tcatcaccga tgccgaagac cgagaaaacg aaggcgacct
    45601 gctgatggcg gcgcaattcg tcacgcccga agccatcaac ttcatgatca aacacgcgcg
    45661 cggcttggtc tgcctgccga tggacggcga aatggtcgaa aaactcgggc tgccgatgat
    45721 gacccaaaaa aacggcgcgc aatacggcac caactttacc gtctccatcg aagccgcaca
    45781 cggcattacc accggcattt ccgccgccga ccgcgccctg actattcaaa ccgccgtttc
    45841 cccgaccgct aaacccgaag acatcgtcca acccggtcat atctttccgc ttcgcgccca
    45901 aaaaggcggc gtactcgtcc gcgccggaca caccgaagcc ggcgtcgacc tggcgcaaat
    45961 gaacgggctg attcctgcct ccgttatttg cgaaatcatc aacgacgacg gcacgatggc
    46021 gcgtatgccc gaactgatga aattcgccga agaacacaag ctcaaaatcg gcacgattgc
    46081 cgacctcatc gaataccgca gccgtaccga aagcctgctt gaagacatgg gcaatgcgcc
    46141 tgtacaaacc ccgtggggcg agttccaaca acacgtttac gtcgacaaac tctccggcga
    46201 aacccacctc gccctcgtca aaggcacgcc ctccgccgac accgaaaccc tcgtccgcgt
    46261 ccacgaaccc ttcagcgtca tggacttcat ccaagccaac ccgcgccatt catggtcgct
    46321 gcccaaagca ctcgagcgca tccaacaggc cgaaagcggc gtagtcatcc ttctgcaccg
    46381 caccgaagac ggcgccgccc tgctcgaccg caccctgccc aaaggtgcaa accaagccta
    46441 caaatgggac agcaaaagct acggcatagg cgcgcaaatc ctcgccggcc tcaacgtcaa
    46501 aaaactgcgc gtcctcgggc agccctcatc tttcaccggc ctgaccggct tcggtttgga
    46561 agtcgtcggc tttgaagaag cggaaaaata atatagtaaa ttcaaatact ttatatttgc
    46621 tttatttatt gcattatttc cgtgcaaacg aaaacccggt ctgttgggtt ggattttgtt
    46681 tttgcaaatt tcgggtaact tctaattcgt cattcccgcg caggcgggaa tccggttcgt
    46741 cgggtttttg tcatttccga taaattcctg tggctttggt tttttggatt ctctctttca
    46801 gggaaagaac ggcataagta ttttccaaac caaacaaaat gccgtctgaa agcctttcag
    46861 acggcatttt aagtttgacc ggtttcattc atcggtattt acgaattgaa ttccaacatt
    46921 gccagcctat ccttaatctc cttttccaat ttggcagatt cggcgaaaag tttatccaaa
    46981 tccgctgaaa atcccgccat tttttgcgca aattcgtcgg cggaaatatc cacataatca
    47041 atctttacct cgaaatactg ccccgccgac aggctgtaat tcttggcttt gatttcatcg
    47101 tagccgacca ccacgctgaa atcttccact gcctgtttgt gcgtgaaagt attgcaaatt
    47161 ttttgttctt cttcgcggga gagtacggtt ttttggtttt tgccgtcttt gattttttcg
    47221 cccaagcccg atgcgtcgat taataccacg ttgtctttat tggctttatc gataaacagg
    47281 atggaaacgt tggttcccgt ggtggcgaaa atattggaag gcatggaaac catgccggcg
    47341 agcattttgt tttctaccag atattcgcgg atttttttgt cgatactcga ttgggcggtg
    47401 ataaagcccg tcggcaacac aatcgccgct ttgccgtttt ctttcaggct aaacaagata
    47461 tgctggataa aaagctggta aatttccatc ttatccgtat cttttgcctt gatttttggg
    47521 ataccggcaa aaaagcgttc gcggttttcc tcgccttcca attgctcgcg aaaatcgctg
    47581 aaatccaatt taaacggtgg attggaaaca atgaaatcaa attttttcag acgacctgaa
    47641 gtgtctttat gggcgggcga caaaatcgta ttaccctgaa ccacattatt caaagaatgc
    47701 accaaattgt tcaaaatcag attcagccgc aaaagattgg acgatttttg cgaaatatcc
    47761 tgcgtataaa tcatacattt gtcttcaccg atggcgtgcg ccacgttcat cagcagcgtt
    47821 cctgaaccgg ctgacggatc gtaaacgtcc acgctgcgga tttgcccacg tacctccttt
    47881 ggcaccaaaa tatccgccat aatccgcgct actgcgtgcg gcgtgtagta ttcggcatat
    47941 ttgccgcccg aattactgtt gtagtcttta atcaggtact caaaaatcgt ggcgaaaaaa
    48001 tcaaattttt gcgcaaaaat cgcctcgaag ctgaaacccg ccagtttgga aatcagcgcg
    48061 tggcaaaaat cgtcgcggcg accttcatcc gtaatatatt gactgatacg ctcgaacaac
    48121 acgattttcg ccccgccttc ggtttttacc gaaaacagtt ccgcattatg tgcggcaata
    48181 tcggtcagcg tatcgtcaaa gagtttggca aagtccgcgc cgttttgtcg ctctgataaa
    48241 tacttgatgg aatgttcagg cttcaaaacg gctgtttttc cctcaatatc catattgatg
    48301 aattcgattg gctcgtcggg attttctttg cgaatttgtt taacttcgaa atcgtatttg
    48361 tcgtttagga atttatacaa aaatgcctga ctgatgattt tgaactcgtt gccgtcattg
    48421 cccaaaccat agttggcgca aatggttttt aagctgtcga ttagggattt ggtttgttcg
    48481 gtaaagtgtt gttcggtcat ttttttctcg tttgttttat tttgtaggtc tgattcttga
    48541 atttggctta ttccgccaca gaaacctgcc cgttcatcag catgggaagt aggaaatcgc
    48601 ggagttgggt tagttggtgg ttttgtttta tattatttcg aactttaaca aagaaagtat
    48661 ttgctatttc attatatttt tgagaaatat ctttactagg taaaattatt ttaaattctt
    48721 ttaagaattt gaaatgtcta gcatatccat aacttgataa atctatttga tttatgattt
    48781 ggtaaaacaa atagtttggc attcgttcat tattgcttaa tattacttgt gtaccatctg
    48841 ctccccgcgc atattgaaaa ttaactaact taacaattct tgtatgatca ccaaaaataa
    48901 tatgagcatc ttgcgggttt aatatagatt tttcatcatt ggtaaatcca caaataaaat
    48961 cttgactttg gtcaacaaca ggatattttc caaaatcctt aatatcttta tttaatattt
    49021 ttgtagtatt tgggattttt gctaagcaag attgtaattc tatacttccc caccccttcg
    49081 gaatttcccg tttcaaggtt tcatcaaaca caatttcgcc gcctgaggat ttgtagggct
    49141 tgccgttggc gtcagggaag tcgaactgca cgaaccaata gtcgtacagg gttttcgcca
    49201 tatcttccag gcgcgcattg atttgtttat tcagggcgat ttttttgtcc aaagcggata
    49261 ggacggcggc gatggattgt tgggttttga ggtcaggaac tgcaaatttt agatttgcaa
    49321 tatcatcagg atttatcgat ggatatgatg aaacactgtt ctcgccaatt gtatgtaaat
    49381 aatcagtgat atgcttttga gtcaataaat agtaaataaa tttttcatcc gtattctcat
    49441 cataaacatc aattgtacta aaccctgttg atataatgaa attatcacca ggattttcca
    49501 aaaaaccgta atgctcctga tttgggcgaa ctgtagaata gataatagtc ttatctttta
    49561 cttttctttt tgcacggcta ggtattttat ccatcatgac attcaaaact tggatattat
    49621 ctatttcatt tctagtaata ttgccagtat ccaaatacat gatttcttga aacatgtctt
    49681 tttgagtgag ggagttggca tttatttctg cgatttcacc aattgtaatt tgtcgtttca
    49741 tcttaactta atctctcgaa actcttcaaa ggccgtctga aaaaaatttc aaaatccaac
    49801 cgcactttta ttgtccactt cgaacgtatg caatacgccc ataaaggcta cctaaaaaac
    49861 cgctttctca catccgcccg ctttctttta aatattcccg caccaacagg cggttgatgg
    49921 cttggatgtc ttggggttga acaggaaatt gttgctccgt tctaaagcgt tttaatacga
    49981 tgccctgcat ttgtttttca aagtaatttt gattgtccaa aatctgctcc atatccagca
    50041 ctttttggtc ggcatcggct ttgacgccgt ttagagcgtt aaaaactttg agtttgtcgc
    50101 cgtagaaggc ggcgttttcc atcagccgct tgtgggtgcg ggcatactta gcgtcgccgc
    50161 cgtatttgtg ccgcaaaagg tcgttttggc ggttcagctc tttgattttg gcatagacga
    50221 tttggagtgt ggcgatgttt gcctgcattt cttcttgccc gacttcggcg aggttctttt
    50281 tcttgaagat gcgttccagc tcttcgcgca ggctgatgta ttcggggtcg tcttggtcga
    50341 agttgcccgc cagcccttca cggactttgc gcatgatgtc ttttaaatcg tcggcaagtt
    50401 tgagttccgc ctcgccgatt ttgacgaatt gaaagtaaac gtcttccagc gcttcattga
    50461 gcaaatgggc ggtgtcgcct tgctgtaatt tttcggcaag gtttaaggta tccagacggg
    50521 cggcagtttc gcggtacaga aggttgagct tgtcaaaatc cagatgcaca agaaattcgt
    50581 ggctgccttg caggcgcaga gcgttgtata gctctttgga agtttgcagg gcttttttta
    50641 gggcgagaag ctgttttttg tcttctattt ggctaatttg gctgcaaaat tcttcggcgt
    50701 tttcggtatc gaaatcaaac agggcgtttt taatgtctgc aatttcctgt tcgatttctt
    50761 cggcggtttt gaatagctgg ctgtaactgc cgatttcgtc gcccaattcg ttagaaagtt
    50821 cgtcccaata ggcgcggttg gttttgtcaa attcgcgttc gatgtcggca aaatcgacaa
    50881 catagccgta acggtaagat ttgtaggtgc ggttgacgcg ggtcagggtt tgtaaaaggt
    50941 tatgggcttt gatgagtctg cccaaataga gctttttcag gcgcggcgcg tcaaagccgg
    51001 tcaaaagcat gttgtacaca aacaggatgt cggttttgcc tgctttgaaa tctttgaccc
    51061 attggtcgcg ttcgtctttg gtgccgacgt cgtgcaatat cagtgcggcg gtgaaattat
    51121 ggtctgaggc cgtctgaaaa tgctcaaaaa gctggcgcgc ctgttctgcg ctatcgcaaa
    51181 cgaccatggc gccgaggctc tcgtcttggt tggtttttct gaatttggcg aagtcgccca
    51241 agatgtaatc gagcatcggg cggacgaaat gcggatgggc gtagatttct ttgcggtcaa
    51301 agctgccttt ttcgacttca agctgcgcca gtgcagcctg caattgggct ttgtattggc
    51361 tgctgatggc ttcgcgaatc aggcgcaggg tgtagccgtc ggcgatggag gcgttgtaat
    51421 agtatttatg gatgtagtcg ccgaagagtt cgcgggtatt gacgttgcct gcggttacgc
    51481 cgataagcgg cgtgccagtc agcccgattt tgacggcgtt tacgtcggac tggttgaggt
    51541 tggcaagaaa cgagcctttg gggttgtagc tgcggtgtac ttcgtcgaga aaatagacgc
    51601 gctgaatggc gaggtcgtag tcgttacgag cgacgacatc ggggtcgtct tggaattttt
    51661 ggatattaac aacagtgatt tccgctttgc ctgcgtggtt gtgcaaagtt tgggcggatt
    51721 tgatgtcggc agcaaaggct tcgcggctgt cgatggtatg gacgactaaa tcgcgggcag
    51781 taaattcgcg ctgcgcctgt ttcaataaat caagcctgtc cacgatgaaa tagaatttcg
    51841 gcacgatgcc ctgtttggca taatagtggg tcaggtagcg ggtgttgtaa taggcaagcg
    51901 cggttttgcc agagccttgg gtgtgccaaa tcacgccttt tttgccgccg tttgccaaat
    51961 gtttttcaat ggcgagagtg gcaaatagct gcggataccg catgatgtgt ttttgcacca
    52021 agccttgact tgctttgacg taagtcagcc cgtgttgcag aagaaaagaa agacgttcgc
    52081 ggcaaagcag cgaagtcagg atgcggttgg tcggcgtatc gggcgattta ttgctgataa
    52141 attcggggct gtgtttgata acgggcaggt tgttgtcttg caggacgttg ttttcgaggc
    52201 cgtctgaaag cgtgttcaat aattcggcaa gatttaattt atgttcttcg cggaagtagt
    52261 taaacacggg cttaccgtaa gcagacgaag cgtaaaacgc gccttgtgcc ggttcggttg
    52321 cgccgtcgtc gtattccatg ttgttggaaa aaatcatgaa ttgggtgatg ttgatgaaac
    52381 ggcgaaattt ggaatttttc gcacgtttgc ccatgcgctc ccgctcttcg ccgattccgc
    52441 ctttgttgtt gggctttttg acttcgataa aaaccaaagg catgccgttt accagcaggg
    52501 taatgtcggg gcggaattct tcatcgccgt tgatacaggg caattcggtt acaacgtgga
    52561 agctgttgtt atcaaaattt tggaagtcga tcagtttctt gccgccggat tgattggtaa
    52621 ggcgttcgta aaacttttgc cccaagtctt cgttgtccag ttctaagcgt atgtcggtca
    52681 gcaaacggcg tgcatcgtcc ggcgacaaat cgggattgat gcggcagagg ctttctataa
    52741 agattttggg aaagatgttg gttggtttat cccaattttc gtttttgagc gagaggtagt
    52801 cgtagcccaa gcgcatcagg tgcaaaacgg cggggatttt gacgcgggaa ttttcgttgt
    52861 gagtttggga cataaacgta atgattcatc aaaatttatt gaaacggatt ataacacctg
    52921 aaaaacccga tacgcctttt tggtgtaccg gctttgccat accgttctgc ttcagacggc
    52981 attgcttcat tttgccttta atgcctcttc atccagcgat ttgagccacg ccagcttttc
    53041 gccgattttg atttccaacc cgcgcgggac gggttggtag aagtccggtt cgtccaagcc
    53101 gtcgggcata tagctttcgc cggcggcgta ggcgttcggt tcgtcgtggg cgtagcggta
    53161 ttcgcgtccg tagcccaatt ccttcatcag cttggtcggg gcgttgcgca ggtggacggg
    53221 cacttcgtcg ctagcgtttt ctttgacgaa gtggcgcatt tggttgtatg ccttgtagcc
    53281 cgcgttggat ttcgcggcgg cggcaagata caataccgct tgcgccaaag ccagttcgcc
    53341 ttcgggcgag cctaagcgtt cgaaggtggc ggcggcatcg ttggcgattt ggaaggcgcg
    53401 cgggtcggca agcccgatgt cttcccaagc gatacgcacg atgcggcggg cgaggtagcg
    53461 cgggtcggtg ccgccgtcga gcatacggca gaaccaatac agcgcggcgt tcggatgcga
    53521 accgcgcacg gatttgtgca gggcggagat ttggttgtag aaactctcgc cgcctttgtc
    53581 gaaacggcgg atttgcgccc cgagactgtc ggcgagaaat tcggcggtta agtttttcag
    53641 acgacgtgta tcggcggcgc gtaaaagttg ttccaacaaa ttcaacaatc tgcgcgcatc
    53701 accgtcggcg gtattcacga gtaatttttg cgcatccgtt tcaatcgtaa actcttggta
    53761 ttcaggcaaa gccaatacct tggcaatcag ctttttcagg tcgtctgaag acaagggttg
    53821 caaaacatac acctgagcgc ggctcaacag cgcgggattg acttcaaacg acggattttc
    53881 cgtcgtcgca ccaataaagg ttagcaaacc gctttcgaca tgcggcaaaa acgcgtcctg
    53941 ctgcgccttg ttgaagcggt ggacttcatc gacaaacaaa atcgtcgcgc gtccctgctg
    54001 caaagcgatt tcggctttat cgattgcctc gcggatgtcc ttcacgccgg aaaatacggc
    54061 ggaaacaggc aaaaactggg cgttgaaact ctgcgccaaa atccgcgcca acgtcgtctt
    54121 gcccacgccc ggcggccccc acagcaacat agaatgcggc ttgccgcctt ctaccgccac
    54181 gcgcaaaggt ttaccttcgc cgatgaggtg ttcctgcccc accacgtcgt caagcgtatg
    54241 cggacgcaat cgttcggcaa gcggcgcgtc gggttctcgg gcaaacaaat cggtcataac
    54301 ggctccgtca acaggttttc aaacaatatg attatacggc agggaacggc ggcgtgccgc
    54361 atacggattc cgcccctccg tttgccttaa gccgatatta ggcgcatact ggaaaagacg
    54421 agagacttca cacaatatat ccggcacgga gaccgattcc gcatcggcat gacaataccc
    54481 aaatcagcgt ttcaattaaa cattaaggag actaaaatag aaaatttgct ttatctacca
    54541 ttgctttgtt gattcaatcg gcattatgtt ttgaggcgga agcccatgaa tatactaata
    54601 ttcaagagat ggaatgggtg tctttatttt ctgatccgca aagagacgat gatagtctta
    54661 taacccttaa agatgaaaaa atcactgtaa aaaactatat tgtgccttgg tggaaaaaag
    54721 gtgaaaactt tagaaaatta gaacttatta ccactggtaa aaatgataat ggaaatttaa
    54781 cggtaaatgg aatttacggc atccaatctt ttgcagactc tcaattggga tatacgcctg
    54841 aattattggt aaaaagcaat aatgatattc tatttaa
//
LOCUS       DAXISH010000007        50265 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.007, whole genome shotgun sequence.
ACCESSION   DAXISH010000007 DAXISH010000000
VERSION     DAXISH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 50265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50265
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.007"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..296)
                     /locus_tag="ACFOV4_000417"
     CDS             complement(<1..296)
                     /locus_tag="ACFOV4_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MJ0042-type zinc finger domain-containing
                     protein"
                     /protein_id="HFC7618502.1"
                     /translation="MPACFCPHCKTRLWVKETQLNVAQGFVVCQKCEGLFKAKDHLAS
                     TKEPIFNDLPEAVSDVKLVHRIGTRAIGKKQISRDEIAGILNGGTTQPDIPPATA"
     gene            complement(370..1011)
                     /gene="pyrE"
                     /locus_tag="ACFOV4_000418"
     CDS             complement(370..1011)
                     /gene="pyrE"
                     /locus_tag="ACFOV4_000418"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFC7618503.1"
                     /translation="MTDFRQDFLKFSLAQNVLKFGEFTTKAGRRSPYFFNAGLFNDGL
                     STLQLAKFYAQSIIESGIRFDMLFGPAYKGIILAAATAMMLAEKGVNVPFAYNRKEAK
                     DHGEGGVLVGAPLKGRVLIIDDVISAGTSVRESIKLIEAEGATPAGVAIALDRMEKGT
                     GELSAVQEVEKQYGLPVAPIASLNDLFILLQNNPEFGQFLEPVRAYRRQYGVE"
     gene            complement(1073..1810)
                     /locus_tag="ACFOV4_000419"
     CDS             complement(1073..1810)
                     /locus_tag="ACFOV4_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010791194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFC7618504.1"
                     /translation="MLSARYLHLHEALGLGPMWLKQAAAVLPPKNTPATPAQARPQTV
                     RAAPIRPSQPHNGQARLETMKALETAAVHTRKPAPETETPPPGLSDGIAPVPAASGIT
                     KLAVVSLCPPIEDAVYGQLFYGKAGVLLDNILKAVGLDAAYVHKTCWVKTAAVGNPMP
                     SEAAIETATVSVMQELDGCRAPAVLFLGQAFVQPERQTMIETLCGSRPFFIIDHPARL
                     LRQPELKARAWQVLKQLKRALRQGGGS"
     gene            complement(1804..2244)
                     /gene="rimI"
                     /locus_tag="ACFOV4_000420"
     CDS             complement(1804..2244)
                     /gene="rimI"
                     /locus_tag="ACFOV4_000420"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFC7618505.1"
                     /translation="MNIRRASPSDCAALAALDAVCNPSAWTQRQFESALVSPSEQVFL
                     AEKDGGIAAFIVWQNLPDESELHLIATAPECRRRGVASALLEYWFAHLPEDTQRLLLE
                     VRAGNTAAQALYAAHGFTDAGRRKNYYRTADGKTEDAVLMEKIC"
     gene            complement(2241..2918)
                     /gene="tsaB"
                     /locus_tag="ACFOV4_000421"
     CDS             complement(2241..2918)
                     /gene="tsaB"
                     /locus_tag="ACFOV4_000421"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFC7618506.1"
                     /translation="MQADFNRPVLAVDTGTSYLSLALRADGETLLFHQEAGSRQSELI
                     LPEIRTLFRNAGITAADLGAIVYAKGPGAFTGLRIGIGVAQGLATPFNTPLIGIPTLD
                     AAASLPPPQSCILAAADARMGEVFYAWFDTLNRRRLSDYQVGRAADIRLPEGCAFSDG
                     IGSAFALEETPPFSGKPDMPTAADFLNLAAEGGFPAVAAAHSELLYVRNKIALTAKEQ
                     AERKART"
     gene            complement(3057..3878)
                     /locus_tag="ACFOV4_000422"
     CDS             complement(3057..3878)
                     /locus_tag="ACFOV4_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="factor H-binding protein"
                     /protein_id="HFC7618507.1"
                     /translation="MNRTAFCCLSLTAALILTACSSGGGGVAADIGAGLADALTTPLD
                     HKDKSLQSLTLDQSVRKNEKLKLAAQGAEKTYGNGDSLNTGKLKNDKVSRFDFIRQIE
                     VDGQTITLASGEFQIYKQNHSAVVALQIEKINNPDKIDSLINQRSFLVSGLGGEHTAF
                     NQLPDGKAEYHGKAFSSDDPNGRLHYSIDFTKKQGYGRIEHLKTPEQNVELASAELKA
                     DEKSHAVILGDTRYGGEEKGTYHLALFGDRAQEIAGSATVKIREKVHEIGIAGKQ"
     gene            complement(4036..5100)
                     /gene="fba"
                     /locus_tag="ACFOV4_000423"
     CDS             complement(4036..5100)
                     /gene="fba"
                     /locus_tag="ACFOV4_000423"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219833.1"
                     /note="catalyzes the reversible aldol condensation of
                     dihydroxyacetonephosphate and glyceraldehyde 3-phosphate
                     in the Calvin cycle, glycolysis, and/or gluconeogenesis;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFC7618508.1"
                     /translation="MALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVNAP
                     VIVQASAGARKYAGAPFLRHLILAAVEEFPHIPVVMHQDHGASPDVCQRSIQLGFSSV
                     MMDGSLMEDGKTPSSYEYNVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGV
                     GAVGKLSHDQMLTSVEDAVRFVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIK
                     EIHQALPNTHIVMHGSSSVPQEWLKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNI
                     DTDLRLASTGAVRRYLAENPSDFDPRKYLSKTIEAMKQICLDRYLAFGCEGQAGKIKP
                     VSLEKMASRYAKGELNQIVK"
     gene            5294..6211
                     /gene="xerC"
                     /locus_tag="ACFOV4_000424"
     CDS             5294..6211
                     /gene="xerC"
                     /locus_tag="ACFOV4_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFC7618509.1"
                     /translation="MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQM
                     PSEDEGGVPQDLSRRDFTAALRRLSQRGLNARTLARKLSSWRQYCVWLVERGLLHTDP
                     TADIKPPKQPERVPKALSQEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIH
                     GLNADDVYLDEAWVHVTGKGRKQRQVPLVGKSVEALKNYLPLRQTASDGKALFTGRNG
                     TRLSQRQIQKRLAQWAAQNGDGRHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLS
                     TTQIYTKLDFDHIARLYDEAHPRAKRQDE"
     gene            6296..8203
                     /gene="dxs"
                     /locus_tag="ACFOV4_000425"
     CDS             6296..8203
                     /gene="dxs"
                     /locus_tag="ACFOV4_000425"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFC7618510.1"
                     /translation="MNPSPLLDLIDSPQDLRRLDKKQLPRLAGELRTFLLESVGQTGG
                     HFASNLGAVELTIALHYVYDTPEDKLVWDVGHQSYPHKILTGRKNQMHTMRQYGGLAG
                     FPKRCESEYDAFGVGHSSTSIGAALGMAAADKLLGSDRRSVAIIGDGAMTAGQAFEAL
                     NCAGDMDVDLLVVLNDNEMSISPNVGALPKYLASNVVRDMHGLLSTVKAQTGKVLDKI
                     PGAMEFAQKVEHKIKTLAEEAEHAKQSLSLFENFGFRYTGPVDGHNVENLVDVLKDLR
                     SRKGPQLLHVITKKGNGYKLAENDPVKYHAVANLPKESAAQMPSENKPAAKPTYTQVF
                     GKWLCDRAAADSRLVAITPAMREGSGLVEFEQRFPDRYFDVGIAEQHAVTFAGGLACE
                     GMKPVVAIYSTFLQRAYDQLVHDIALQNLPVLFAVDRAGIVGADGPTHAGLYDLSFLR
                     CVPNMIVAAPSDENECRLLLSTCYQADAPAAVRYPRGTGTGAPVSDGMETVEIGKGII
                     RREGGKTAFIAFGSMVAPALAVAEKLNATVADMRFVKPIDEELIVRLARSHDRIVTLE
                     ENAEQGGAGGAVLEVLAKHGICKPVLLLGVADTVTGHGDPKKLLDDLGLSAEAVERRV
                     RAWLSDRDAAN"
     gene            complement(8288..9616)
                     /gene="miaB"
                     /locus_tag="ACFOV4_000426"
     CDS             complement(8288..9616)
                     /gene="miaB"
                     /locus_tag="ACFOV4_000426"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HFC7618511.1"
                     /translation="MKKVFIRTFGCQMNEYDSDKMLAVLAEEHGGIEQVTQADEADII
                     LFNTCSVREKAQEKVFSDLGRVRPLKEKNPGLIIGVAGCVASQEGENIIKRAPYVDVV
                     FGPQTLHRLPKMIVDKETSGLSQVDISFPEIEKFDHLPPARVEGGAAFVSIMEGCSKY
                     CSFCIVPYTRGEEFSRPLNDVLTEIANLAQQGVKEINLLGQNVNAYRGEMDDGEICDF
                     ATLLRIVHEIPGIERMRFTTSHPREFTDSIIECYRDLPKLVSHLHLPIQSGSDRVLSA
                     MKRGYTALEYKSIIRKLRAIRPDLCLSSDFIVGFPGETEREFEQTLKLVKDIAFDLSF
                     VFIYSPRPGTPAANLPDDTPHEEKVRRLEALNEVIEAETARINQTMIGTVQRCLVEGI
                     SKKDPDQLQARTANNRVVNFTGTPDMINQMIDLEITEAYTFSLRGKVVEA"
     gene            9819..9899
                     /locus_tag="ACFOV4_000427"
                     /pseudo
     CDS             9819..9899
                     /locus_tag="ACFOV4_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712609.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-fructose-6-phosphate
                     aminotransferase"
     gene            10002..10385
                     /locus_tag="ACFOV4_000428"
     CDS             10002..10385
                     /locus_tag="ACFOV4_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010950978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-fructose-6-phosphate
                     aminotransferase"
                     /protein_id="HFC7618512.1"
                     /translation="MYCLRLRRLVLIFVNPLYQTEEGIAQTVVKGKTTRAEVEARFGK
                     RNPFGCYAYHEVSLPIYNFLPTNFIYMKSERRHWEWCVDYDWEGVVRDYRFTHKVEKD
                     ERSVIRDAVGVIRKEAGKSLSQPEK"
     gene            10449..11732
                     /gene="hemL"
                     /locus_tag="ACFOV4_000429"
     CDS             10449..11732
                     /gene="hemL"
                     /locus_tag="ACFOV4_000429"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HFC7618513.1"
                     /translation="MNRNEILFDRAKAVIPGGVNSPVRAFGSVGGVPRFIKKAEGAYV
                     WDENGTRYTDYVGSWGPAIVGHAHPEVVEAVREAALGGLSFGAPTEGEIVIAEQIAEI
                     MPSVERLRLVSSGTEATMTAIRLARGFTGRDKIIKFEGCYHGHSDSLLVKAGSGLLTF
                     GNPSSAGVPADFTKHTLVLEYNNIAQLEEAFAQSGNDIACVILEPFVGNMNLVRPTEA
                     FVKALRELTEKHGAVLIYDEVMTGFRVALGGAQSLHGITPDLTTMGKVIGGGMPLAAF
                     GGRKDIMECISPLGGVYQAGTLSGNPIAVAAGLKTLEIIRREGFYENLTARTEQLVQG
                     FQTAADAAGIEFTADSVGGMFGLYFASHTPQNYGDMARSNIEGFKQFFHGMLDRGIAF
                     GPSAYEAGFVSAAHTPELIDETVAVAVEVFKAMAA"
     gene            complement(11948..12220)
                     /locus_tag="ACFOV4_000430"
     CDS             complement(11948..12220)
                     /locus_tag="ACFOV4_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taxon MazF"
                     /protein_id="HFC7618514.1"
                     /translation="MPSEAQILHFRRHFYSRLKSKIYTPVIPAQAGIRKVGLVGHEVV
                     LKMKRYRKSDELKEKYSDIDETFEFIKGFIYVIALAFTAYVAIRFF"
     gene            complement(12231..12794)
                     /gene="orn"
                     /locus_tag="ACFOV4_000431"
     CDS             complement(12231..12794)
                     /gene="orn"
                     /locus_tag="ACFOV4_000431"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HFC7618515.1"
                     /translation="MQDKNNLCWLDMEMTGLNPETDRIIEVAMIITDSDLNVLAQSEV
                     YAIHQSDELLDNMDEWNTATHGRTGLTQRVRESSHTEAEVEQKLLDFMSEWVPERATP
                     MCGNSIHQDRRFMVKYMPKLENYFHYRNLDVSTLKELAKRWNPPVAKSVVKRGSHKAL
                     DDILESIEEMRHYREHFLISAPRAEAQ"
     gene            complement(12812..13699)
                     /gene="prmA"
                     /locus_tag="ACFOV4_000432"
     CDS             complement(12812..13699)
                     /gene="prmA"
                     /locus_tag="ACFOV4_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFC7618516.1"
                     /translation="MPYQQITVNVNDAVAERLADALMEHGALSAAIEDAYAGTQNEQA
                     IFGEPGMPAEQIWQQSKVIALFGEHDEAAAIIQTAAQECGLKDLAYTGEILEDQDWVR
                     LTQAQFDPIRISERLWITPSWHEAPEGTAVNLRLDPGLAFGTGSHPTTRLCLKWLDTQ
                     LKNGESVLDYGCGSGILTIAALKLGAGSAVGVDIDEQAVRAGKDNAEQNNVDAQFFLP
                     DGLPQGQFDVVVANILANPLRMLGEMLAARTKQGGRIVLSGLLDEQAEELGGIYSQWF
                     DLDPAETEESWARLSGTKR"
     gene            complement(13817..15178)
                     /gene="accC"
                     /locus_tag="ACFOV4_000433"
     CDS             complement(13817..15178)
                     /gene="accC"
                     /locus_tag="ACFOV4_000433"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFC7618517.1"
                     /translation="MLKKVLIANRGEIALRVLRACREMGIATVAVHSEADKDSLHVKL
                     ADESVCIGPAASAQSYLNVPAIIAAAEVSCADAVHPGYGFLAENADFAEQVEQSGFTF
                     IGPKPDTIRLMGDKVSAKHAMIAAGVPCVPGSDGALPDDGEEILKIADKVGYPVIIKA
                     SGGGGGRGMRVVEKKEDLLQSVEMTKAEAGAAFGNPMVYMERYLQRPRHVEIQVIADE
                     HGNAIYLAERDCSLQRRHQKVIEEAPAPFITEKERAKIGNACADACKRIGYRGAGTFE
                     FLYEDGEFFFIEMNTRVQVEHPVTELITGVDIVQEQLRIAAGLPLQYKQKDIQVEGHA
                     FECRINAEDPYNFIPSPGPIESCHLPGGFGIRVDSHIYQGYRIPPYYDSLIGKICVHG
                     KTREQAMAKMRVALAELAVTGIKTNTPLHRDLFADAGFQKGGVSIHYLEHWLEDRKAK
                     QDK"
     gene            complement(15292..15744)
                     /gene="accB"
                     /locus_tag="ACFOV4_000434"
     CDS             complement(15292..15744)
                     /gene="accB"
                     /locus_tag="ACFOV4_000434"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFC7618518.1"
                     /translation="MDLRKLKKLIDLVEESGIAEIEVTEGEEKVRITRTIAAAPVYAA
                     PVPAAAPAVTPAAAPVAASAPAAPAARDLSDAQKSPMVGTFYRAPGPNAAPFVEVGQQ
                     VKAGDTLCIIEAMKLMNEIEAEKSGTVKEILVENGTPVEFGEPLFIIG"
     gene            complement(15726..15983)
                     /locus_tag="ACFOV4_000435"
     CDS             complement(15726..15983)
                     /locus_tag="ACFOV4_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase"
                     /protein_id="HFC7618519.1"
                     /translation="MRKIKLPAHFPQKPPFFDILLDIYRQLRENKHILTVVFHHRKTV
                     SEHHSARFAPLPQAGCFLKNQRNNPPEHRQPLKEQKWICAN"
     gene            16100..17140
                     /gene="queA"
                     /locus_tag="ACFOV4_000436"
     CDS             16100..17140
                     /gene="queA"
                     /locus_tag="ACFOV4_000436"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFC7618520.1"
                     /translation="MDISDFDFTLPEKLIAQHPPEVRGSSRLLVALPDMPLQDRVFGD
                     LPDYVEAGDVLVFNNTKVMKARLFGQKDSGGRIEALIERVLDNHTALAHIRSSKSPKP
                     GMGLVFEGGIRAVMVGREGELFCLRFEGGQTVYELLEQNGHLPLPPYIERAADADDDS
                     RYQTVYAKYQGAVAAPTAGLHFTEELLHRLKDKGAVTAEVTLHVGAGTFQPVRVEKIE
                     EHKMHSEWFEVPSETAAAVEAAKARGNKVWAVGTTSMRALESAARATGRLKAGQGDTD
                     IFITPGYRFNVADRLVTNFHLPKSTLLMLVSAFSGMGHIRAAYRYAVEREYRFFSYGD
                     AMVLGRNEGVVR"
     gene            complement(17614..18192)
                     /locus_tag="ACFOV4_000437"
     CDS             complement(17614..18192)
                     /locus_tag="ACFOV4_000437"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005694496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFC7618521.1"
                     /translation="MNILLLDGGKAFGHSHGGLNRTLHKKAKEVLTALGHNVQETVID
                     AGYDVEAEIEKFVWMDAVIWQMPGWWMHEPWTVKKYIDEVLTAGHGKLYQSDGRHRVN
                     PTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMT
                     RLPTFLCNDVVKNPQVEKYLADYQAHLEKVFG"
     gene            18431..19330
                     /gene="crgA"
                     /locus_tag="ACFOV4_000438"
     CDS             18431..19330
                     /gene="crgA"
                     /locus_tag="ACFOV4_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_151940473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator CrgA"
                     /protein_id="HFC7618522.1"
                     /translation="MKTNSEELTVFVQVVESGSFSRAAEQLAMANSAVSRIVKRLEEK
                     LGVNLLNRTTRQLSLTEEGAQYFRRAQRILQEMAAAETEMLAVHEIPQGVLRVDSAMP
                     MVLHLLAPLATKFNERYPHIRLSLVSSEGYINLIERKVDIALRAGELDDSGLRARHLF
                     DSRFRVIASPEYLAKHGTPQSTEELAGHQCLGFTEPGSLNTWAVLDAQGNPYKISPHF
                     TASSGEILRSLCLSGCGIACLSDFLVDNDIAEGKLIPLLAEQTSDKTHPFNAVYYSDK
                     AVNLRLRVFLDFLVEELGNNLCG"
     gene            complement(19560..22775)
                     /gene="carB"
                     /locus_tag="ACFOV4_000439"
     CDS             complement(19560..22775)
                     /gene="carB"
                     /locus_tag="ACFOV4_000439"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFC7618523.1"
                     /translation="MPKRTDLKSILIIGAGPIVIGQACEFDYSGAQACKALREEGYKV
                     ILVNSNPATIMTDPEMADVTYIEPIMWQTVEKIIAKERPDAILPTMGGQTALNCALDL
                     ARNGVLAKYNVELIGATEDAIDKAEDRGRFKEAMEKIGLSCPKSFVCHTMNEALAAQE
                     QVGFPTLIRPSFTMGGSGGGIAYNKDEFLAICERGFDASPTHELLIEQSVLGWKEYEM
                     EVVRDKNDNCIIICSIENFDPMGVHTGDSITVAPAQTLTDKEYQIMRNASLAVLREIG
                     VDTGGSNVQFAMNPENGEMIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGFTLDE
                     LRNDITGGKTPASFEPSIDYVVTKIPRFAFEKFPAADDRLTTQMKSVGEVMAMGRTIQ
                     ESFQKALRGLETGLCGFNPRSSDKAEIRRELANPGPERMLFVADAFRAGFTLEEIHEI
                     CAIDPWFLAQIEDLMKEEKAVSDGILSDLDFAALRRLKRKGFSDKRLAQLLNVSEKEV
                     REHRYALKLHPVYKRVDTCAAEFATETAYLYSTYEEECEARPSDRKKVMILGGGPNRI
                     GQGIEFDYCCVHAALALRESGFETIMVNCNPETVSTDFDTSDRLYFEPLTLEDVLEIV
                     RTENPWGVIVHYGGQTPLKLANALVENGVNIIGTSADSIDAAEDRERFQKVLNDLGLR
                     QPPNRIAHNEEEALVKAEEIGYPLVVRPSYVLGGRAMQIVHSAEQLQKYMREAVQVSE
                     DSPVLLDFFLNNAIEVDVDCVSDGKDVVIGGIMQHVEQAGIHSGDSGCSLPPYSLSEE
                     IQDEIRRQTKAMAYALGVVGLMNVQFAVQDGVVFVLEVNPRASRTVPFVSKATGVPLA
                     KVGARCMAGISLKEQGVEKEVVPDFYAVKEAVFPFIKFPGVDTILGPEMRSTGEVMGV
                     GASFGEAYYKAQLGAGERLNPTGKIFLSVREEDKERVIKTAKNFQALGYGICATRGTA
                     QYLTEHGLIVQTINKVPEGRPHIGDALKNGEIALVVNTVSSDPQSVSDSHIIRQSALQ
                     QRVPQYTTTAGGEAMSEGAKSRDHLGVYSVQELHGRLKNRN"
     gene            complement(22815..23243)
                     /locus_tag="ACFOV4_000440"
     CDS             complement(22815..23243)
                     /locus_tag="ACFOV4_000440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618524.1"
                     /translation="MTEAVNLNNFAARKIIKQLYYTDELNLNLVRQLQKEIQQEEPFD
                     GCSDELKPTLIGINELLETHGSESQKHLLTPIISELKELNQIKHDHKKMKTQSYIAYI
                     IAIISFFIGSISFYYTITAPSGKEIANTVVEQLKANQNQQ"
     gene            complement(24273..24662)
                     /locus_tag="ACFOV4_000441"
     CDS             complement(24273..24662)
                     /locus_tag="ACFOV4_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF559 domain-containing protein"
                     /protein_id="HFC7618525.1"
                     /translation="MNPHEKLLTTDNPILRQRAKAMRQEMSEAEAKLWQHLRAGRLNG
                     YKFRRQQPMGNYIVDFMCVTPKLIVEADGGQHAEQAVYDHARTAYLNSLGFTVLRFWN
                     HEILQQTNDVLTEILLVLQELEKQAAR"
     gene            complement(25235..25360)
                     /locus_tag="ACFOV4_000442"
                     /pseudo
     CDS             complement(25235..25360)
                     /locus_tag="ACFOV4_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687733.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(25406..26539)
                     /gene="carA"
                     /locus_tag="ACFOV4_000443"
     CDS             complement(25406..26539)
                     /gene="carA"
                     /locus_tag="ACFOV4_000443"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HFC7618526.1"
                     /translation="MSTPALLVLADGSVFHGTSIGYEGSTSGEVVFNTSMTGYQEILT
                     DPSYCKQIVTLTYPHIGNTGTNAEDEESRSVYASGLIIRDLPLLHSNFRASESLHDYL
                     VRNQTVAIADIDTRRLTTLLREKGAQGGAILTGADATIEKAQELIAAFGSMVGKDLAK
                     EVSCTETYEWTEGEWELGKGFVTPDEQPYHVVAYDFGVKTNILRMLASRGCRLTVVPA
                     QTSAQDVLALNPDGVFLSNGPGDPEPCTYAIEAVQKLMESGKPIFGICLGHQLISLAI
                     GAKTLKMRFSHHGANHPVQDLDSGKVVITSQNHGFAVDADTLPANARITHKSLFDNTL
                     QGIELTDKPVFCFQGHPEASPGPQDVGYLFDKFIGNMKAAKRA"
     gene            complement(27106..30081)
                     /gene="pilC"
                     /locus_tag="ACFOV4_000444"
     CDS             complement(27106..30081)
                     /gene="pilC"
                     /locus_tag="ACFOV4_000444"
                     /inference="COORDINATES: protein motif:HMM:NF040838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilC family type IV pilus tip adhesin"
                     /protein_id="HFC7618527.1"
                     /translation="MNEQNQPEVKQEGSYSTLREKDRERKFIYNKGRSGGGSVSFNNS
                     DELVSRQSGTAVFGTATYLPPYGKVSGFDADGLEKRNNAAGWIRTTRIALAGYSYASV
                     VCKSSTGCPKLVYKTRFSFDNPDLEKIGGRLDRHTDPSRDNSPIYKLKDHPWLGVSFN
                     LGSENTVKNGKSSSKLISSFNENNNNQTIVSTTEGDPISLGDQQREHTAVVYYLNAKL
                     HLLDKKGIKDITDKTVQLGVLRPSIDVRLQRNTGLAGLLNFWASWDIKDNGQIPVKLG
                     LPEVKAGRCINANNPNKSTKAPSPALTAPALWFGPVQNGKMEMYSASVSTYPDSSSSR
                     IFLQNLKRKNDPNKPGRYSLATLNKSDIESREPTFTGRQTVIRLDKGVHQIKLKGNEV
                     EGFKGNNGNDTFGIVSEGSFMPDDSEWKKVLLPWTVRGVNDDQFKTFNKEEKNGKPKY
                     SQKYRSRDNGNNSKRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKGNGGDERNYSLK
                     LSYIPGTMPRKDIESKDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVNLNGKDHVFM
                     FGAMGFGGRGAYALDLTKADGSDPTAVSLFDVKHDNNGNNSNNSVQLGYTVGTPQIGK
                     THDGKYAAFLASGYATKTIDDQQNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLV
                     DKDLDGTVDIAYAGDRGGKMYRFDLSGQDPQQWSVRTIFSGNKPITSAPAISQLKDKR
                     VVIFGTGSDLSEEDVDNNDIQSIYGIFDNDTDTGTAQDGQGKGLLEQKLSEENKTLFL
                     TDYKRSDGSGDKGWVVKLQPGQRVTVKPTVVLRTAFVTIRKYNDGGCGAETAILGINT
                     ADGGKLTKKSARPIVPEANTAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDK
                     PVNVRYLDEKKTDGFSTTADGDAGGSGIDPDGKRSGKNNRCFSQKGVRTLLMNDLDSL
                     DITGPTCGMKRISWREVFY"
     gene            complement(30078..30200)
                     /locus_tag="ACFOV4_000445"
     CDS             complement(30078..30200)
                     /locus_tag="ACFOV4_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618528.1"
                     /translation="MNKTLKRRVFRHTALYAAILMFSHTGGGGRRRKPITTLLS"
     gene            complement(31457..32536)
                     /gene="apbC"
                     /locus_tag="ACFOV4_000446"
     CDS             complement(31457..32536)
                     /gene="apbC"
                     /locus_tag="ACFOV4_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017146699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HFC7618529.1"
                     /translation="MNIQNIRTLLDTVAVPNTARTLGGEKAVRSVEQRSDGIHIALHF
                     GFPVAHIASETADRIQEILMPLTGDTHIHLSMDTEIGTHKVQPGVTTIKGVKNIIAVA
                     SGKGGVGKSTTTANLAAAMARMGARVGVLDADLYGPSQPTMLGVDDRKPDQKNQKLIP
                     VESSDGIQVMSIGFLVDTDQAVVWRGPMVSQALQQLMFQSEWDEVDYLFIDLPPGTGD
                     IQLTLSQRIPVTGSVIVTTPQDIALIDARKAVDMFRKVNIPILGVLENMSVHICTNCG
                     HSEALFGTDGGKDLAARLNVPLLGQLPLSLPVREAMDGGTPAQLFDEHPAIARIYTDA
                     AFQIALGIADKGKDFSSRFPKIVVE"
     gene            32747..32822
                     /locus_tag="ACFOV4_000447"
     tRNA            32747..32822
                     /locus_tag="ACFOV4_000447"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32780..32782,aa:Lys,seq:ttt)
     gene            32901..33410
                     /locus_tag="ACFOV4_000448"
     CDS             32901..33410
                     /locus_tag="ACFOV4_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein disulfide oxidoreductase"
                     /protein_id="HFC7618530.1"
                     /translation="MKKKLLSGIKFAVQTALVFLLVSLFLDWIRKPEEPAGAAGRPLT
                     LLSGQRLTLGQFSRDKAILVYFWGSWCGVCRYQSPIIDDLAADGVPVVGVAVRSGSAS
                     EVAAYMAKRGLGFPTVNDEDGGLARSWRIVATPAVVLVKNGKMVHYTTGISSYWGLRA
                     RIFQADVFG"
     gene            33753..34193
                     /gene="nadR"
                     /locus_tag="ACFOV4_000449"
     CDS             33753..34193
                     /gene="nadR"
                     /locus_tag="ACFOV4_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family adhesin repressor NadR"
                     /protein_id="HFC7618531.1"
                     /translation="MPNQSKHASINISLIQAREALMTQFRPILNQANITDQQWRIIRL
                     LAENGTLDFQDLANQACILRPSLTGILTRLEKAGLVVRLKPSNDQRRVFLKLTAEGEK
                     LYEEIGEEVDERYDAIEEVLGREKMLLLKDLLAELAKIEDALNS"
     gene            34308..34808
                     /gene="hpaC"
                     /locus_tag="ACFOV4_000450"
     CDS             34308..34808
                     /gene="hpaC"
                     /locus_tag="ACFOV4_000450"
                     /EC_number="1.14.14.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0042537 - benzene-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase,
                     reductase component"
                     /protein_id="HFC7618532.1"
                     /translation="MADLQKTFQTSFRDAMASCAAGVHVITTDGAAGRYGITMTAVAP
                     VTDEPPTVMLCINRSARIIPILSENGSLCINTLADEHQDVAEHFAGLTNLSPEERFAY
                     HIWHYGKTGQPEIEGALAHLHGHIVGQHEIGTHFVFYVRLDEIKNCVGKRPALLYFRR
                     QFRSLD"
     gene            34826..35521
                     /gene="murU"
                     /locus_tag="ACFOV4_000451"
     CDS             34826..35521
                     /gene="murU"
                     /locus_tag="ACFOV4_000451"
                     /EC_number="2.7.7.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramate alpha-1-phosphate
                     uridylyltransferase MurU"
                     /protein_id="HFC7618533.1"
                     /translation="MKAMILAAGRGERMRPLTDTTPKPLLDVAGKPLIGWHLCRLKQA
                     GFTEIVINHAWLGRQIEEALGDGSAYGVNIAYSPEPEGGLETAGGIARALPLLGDAPF
                     LVVNGDVLTDIDFTAAFQAASSLPEHISAHLWLVENPPHHPDGDFSLLPDGSVRPEVN
                     GGNGLTFSGVGIYRPEMFDGIEAGSVAKLAPVLRNEMRQNRVSGQKHTGLWLDVGTVC
                     RLKEAQALAGAWK"
     gene            complement(35752..36183)
                     /locus_tag="ACFOV4_000452"
     CDS             complement(35752..36183)
                     /locus_tag="ACFOV4_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HFC7618534.1"
                     /translation="MGSNAWLFWALASAGFASLTAVFAKMGLQGIDSDFATFIRTLVI
                     LAALVLFLTYTGKWQGVNGFTGHNWTFLILSGLATGASWLAYFKALQLGNASQVAPVD
                     KFSLVLVALMAVVFLDERPNTQEWIGLGLVTAGVLVLALKR"
     gene            36358..38034
                     /locus_tag="ACFOV4_000453"
     CDS             36358..38034
                     /locus_tag="ACFOV4_000453"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFC7618535.1"
                     /translation="MSFKTDAEIAQSSTMRPIGEIAAKLGLNADNIEPYGHYKAKINP
                     AEAFKLPQKQGRLILVTAINPTPAGEGKTTVTIGLADALRHIGKDAVIALREPSLGPV
                     FGVKGGAAGGGYAQVLPMEDINLHFTGDFHAIGAANNLLAAMLDNHIYQGNELNIDPK
                     RVLWRRVVDMNDRQLRNIIDGMGKPVDGVMRPDGFDITVASEVMAVFCLAKDISDLKE
                     RLGNILVAYAKDGSPVYAKDLKANGAMAALLKDAIKPNLVQTIEGTPAFVHGGPFANI
                     AHGCNSVTATRLAKHLADYAVTEAGFGADLGAEKFCDIKCRLAGLKPDAAVVVATVRA
                     LKYNGGVERANLGEENLDALEKGLPNLLKHISNLKNVFGLPVVVALNRFVSDSDAELA
                     MIEKACAEHGVEVSLTEVWGKGGAGGADLARKVVNAIESQTNNFGFAYDVELGIKDKI
                     RAIAQKVYGAEDVDFSAEASAEIASLEKLGLDKMPICMAKTQYSLSDNAKLLGCPEGF
                     RIAVRGITVSAGAGFIVALCGNMMKMPGLPKVPAAEKIDVDEHGVIHGLF"
     gene            38147..39238
                     /gene="ychF"
                     /locus_tag="ACFOV4_000454"
     CDS             38147..39238
                     /gene="ychF"
                     /locus_tag="ACFOV4_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002642527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFC7618536.1"
                     /translation="MSLKCGIVGLPNVGKSTLFNALTQSGIEAANYPFCTIEPNVGIV
                     EVPDPRMAELAKIVNPQKMQPAIVEFVDIAGLVAGASKGEGLGNQFLANIRETDAIVN
                     VVRCFDDDNIVHVSGKVDPIADIETIGTELALADLASVEKAIVREEKRARSGDKDAQK
                     LVDLCKKLLPHLDEGKPVRSFGLDAEERAMLKPLFLLTAKPAMYVGNVSEDGFENNPH
                     LDRLKELAAKENAPVVAVCAAMESEIAELEDGEKAEFLAEMGLEEPGLNRLIRAGYDL
                     LGLQTYFTAGVKEVRAWTIHKGDTAPQAAGVIHTDFERGFIRAQVISYDDFVSLGGEA
                     KAKEAGKMRVEGKEYVVQDGDVMHFLFNV"
     gene            39605..41485
                     /locus_tag="ACFOV4_000455"
     CDS             39605..41485
                     /locus_tag="ACFOV4_000455"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFC7618537.1"
                     /translation="MSQALPYRPDIDTLRAAAVLSVIVFHIEKNWLPGGFLGVDIFFV
                     ISGFLMTMILHREMSGGGGRFSLKAFYIRRIKRILPAFFAVLAATLTGGFFLFTKDDF
                     FLLWKSALTALGFASNLYFARGKDYFDPAQEEKPLLHIWSLSVEEQFYFVFPILLLLV
                     ARKSPRVQFGFLAALCALSLAASFMPSAFDKYYLPHLRACEMLVGSLTAVWMRYRQQR
                     NLAVGRCCAAAGALFSACILSACLFAYSKQTAYFPGPAALIPCLAVAALIYFNHYEHP
                     LKKFFQWKITVAAGLISYSLYLWHWPILAFMRYIGPDNLPPYSTAAAIVLILLLSLIS
                     YHCIEKPFKKWKGSFAQSVLWIYALPMLILGAGSFFAMRLPFMAQYDRLGLTRSNTSC
                     HNNTGKQCLWGDTEKQPELLVLGDSHADHYKTFFDAVGKKEKWSATMVSADACAYVEG
                     YASRVFQNWAACRAVYRYAEEHLPLYSKVVLAMRWGSQMPENSRSLAYDAGFFQKFDR
                     MLHKLSSEKQAVYLMADNLASSYNVQRAYILSSRIPGYRQTLRPDDESTLKANARIRE
                     LAAKYPNVYIIDAAAYIPANFQIGGLPVYSDKDHINPYGGTELAKRFSEKQRFLDTRH
                     NH"
     gene            41548..42843
                     /gene="tyrS"
                     /locus_tag="ACFOV4_000456"
     CDS             41548..42843
                     /gene="tyrS"
                     /locus_tag="ACFOV4_000456"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFC7618538.1"
                     /translation="MSVIQDLQSRGLIAQTTDIEALDALLNEQKISLYCGFDPTADSL
                     HIGHLLPVLALRRFQQAGHTPIALVGGATGMIGDPSFKAAERSLNSAETVAGWVESIR
                     SQLTPFLSFEGGNAAIMANNADWFGKMNCLDFLRDIGKHFSVNAMLNKESVKQRIDRD
                     GAGISFTEFAYSLLQGYDFAELNKRHGAVLEIGGSDQWGNITAGIDLTRRLYQKQVFG
                     LTLPLVTKSDGTKFGKTEGGAVWLNAKKTSPYQFYQFWLKVADADVYKFLKYFTFLSI
                     EEIDAIEAKDKASGSKPEAQRILAEEMTRLIHGEEALAAAQRISESLFAEDQSSLTES
                     DFEQLALDGLPAFEVSDGINVVEALVKTGLASSNKEARGFVNSKAVLLNGKPAEANNP
                     NHAAERPDDACLLNGEHKRFGKYTILRRGKRNHALLVWK"
     gene            43370..44290
                     /gene="ribF"
                     /locus_tag="ACFOV4_000457"
     CDS             43370..44290
                     /gene="ribF"
                     /locus_tag="ACFOV4_000457"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HFC7618539.1"
                     /translation="MRIRLGRHNAPDFPHGAAVTIGNFDGVHLGHKHILQKLRLEADT
                     RGLPVVTVVFEPQPKEFFALRTGRMPPCRISPLRTKLELLEGTGCVDAVWVLRFDQNF
                     SEISAQGFIDRLLRQTLNTRYLLVGDDFRFGAGREGCFELLAQQPDMQTERTPSVIVE
                     DIRTSSTAVRQALSDGNLAYAKKLLGHDYVLSGRVVHGRKLGRTLNAPTANIRLPRHR
                     YALGGVFVVEADGAFGTRRGVASFGFNPTVDSGCSQKLEVHLFDFQGDLYGQRLNVRF
                     LHKLRDEEKFDGMAELKRQIAADMEAAKCW"
     gene            44431..47220
                     /gene="ileS"
                     /locus_tag="ACFOV4_000458"
     CDS             44431..47220
                     /gene="ileS"
                     /locus_tag="ACFOV4_000458"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFC7618540.1"
                     /translation="MTDYSKTVNLLESPFPMRGNLAKREPAWLKSWYEQKRYQKLREI
                     AKGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIRSKTQAGFDAPYVPGWDCHGLPI
                     EVMVEKLHGKDMPKARFRELCREYAAEQVARQKKDFIRLGVLGDWDRPYLTMDFKTEA
                     DTVRMLGEIYKSGYLYRGAKPVQFCLDCGSSLAEAEVEYKDKISPAIDVAYPFKDTAA
                     LAAAFGLAGIEGKAFAVIWTTTPWTLPASQAVSAGADVVYQLIDTPKGKLVLAKDLAE
                     DALKRYGFSDGISILAETTGDKLENLHMNHPFLERDIPMLNGEHVTTDAGTGLVHTAP
                     AHGLEDYAVCNKYGIELYNPVNAEGKYIGETLRVAGMRVWEANPVILQWLEETGNLLA
                     SSKIEHSYAHCWRHKTPLIYRATGQWFVGMDKAGADGKTLRDKAIKAVDDTEFFPSWG
                     RARLEAMIEGRPDWVVSRQRYWGTPMTFFVHKETGELHPNSAELLEKVALKIEEKGIE
                     AWFSLDKSELLSAEDCEHYDKLPDTMDVWFDSGSTHYSVVKQREELEWPADLYLEGSD
                     QHRGWFQSSMLTGCASSMGRAPYKQLLTHGFVVDGEGKKMSKSIGNVVAPQEVYNEFG
                     ADILRLWAASTDYSGELAISKEILKRVTESYRRIRNTLSFLFANLSDFNPIEDAVQQA
                     DMVEIDRYALVLARRLQERLAGDYYPRYAFHFAVKDIVSFCSEDLGAFYLDILKDRLY
                     TTKADSHARRSAQTALYHITRSLVLLIAPILCFTGEEAWDIIGGGEEDSVLFHTWHEF
                     PTINEKAEAELVKKWTAIREAREAVTAAIEPLRADKTVGSSLQAEAEITAPEEMASYL
                     NALGEELRFALLVSKAEVKVGDELAVAAKASDGEKCERCWHYTHDVGAVAGHETICKR
                     CAGNVGGEGETRHYA"
     gene            48093..48590
                     /gene="lspA"
                     /locus_tag="ACFOV4_000459"
     CDS             48093..48590
                     /gene="lspA"
                     /locus_tag="ACFOV4_000459"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFC7618541.1"
                     /translation="MSSSVSSKTRYWVLALAAIVLDQWSKWAVLSSFQYRERVNVIPS
                     FFDLTLVYNPGAAFSFLADQGGWQKYFFLVLAVTVSAYLVRAILRDEFATLGKTGAAM
                     IIGGALGNVIDRLIHGHVVDFLLFYWQNWFYPAFNIADSFICVGAVLAVLDNIVHRKT
                     QEEKY"
     gene            48619..49587
                     /gene="ispH"
                     /locus_tag="ACFOV4_000460"
                     /gene_synonym="lytB"
     CDS             48619..49587
                     /gene="ispH"
                     /locus_tag="ACFOV4_000460"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA];
                     GO_process: GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HFC7618542.1"
                     /translation="MNEKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVH
                     NKFVVDNLREKGAVFIEDLAEVPPGATLVYSAHGVSKAVQQEAAERGFRVFDATCPLV
                     TKVHKEVARLDAQDCEIIMIGHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPD
                     KLAYVSQTTLSVDETKDIIAALNARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIV
                     IVVGSPNSSNSNRLREVAASRGIDAYMVDNAGYLQRAWFEGKNKVGVTAGASAPEVLV
                     QEVLATIRGWGHETVREGEGAEESIVFVLPKELRREGETKPDLCKR"
     gene            complement(49674..50237)
                     /locus_tag="ACFOV4_000461"
     CDS             complement(49674..50237)
                     /locus_tag="ACFOV4_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFC7618543.1"
                     /translation="MCWGFGCREGKEFCKGLSLPEIIRDLLEMPSETAIADITRTYSA
                     HYLNPNNRNMSLFPQALPCLDKLKAQGYWLAVATGKGRAGLDNAISQTATGGYWLATA
                     CAGEYPSKPSPEMVFGICGKLGLDPKEALVVGDTAHDLHMAANAGAAAVGVATGAHSR
                     EQLLGAPHLAVLDDLSELPGFLAQHYA"
BASE COUNT        10911 a        13086 c        14173 g        12095 t
ORIGIN      
        1 gcggttgcgg gcggaatatc gggctgggtt gtgccgccgt tgaggatgcc ggcgatttcg
       61 tcacgggaaa tctgtttctt gccgatggcg cgcgtgccga tacggtgaac gagtttgaca
      121 tccgaaacag cctcgggcaa atcgttgaat atgggttctt tcgtgcttgc cagatggtct
      181 ttggctttaa acagtccttc gcatttttgg cagacgacga agccttgggc gacattgagt
      241 tgggtttctt tgacccagag acgggttttg cagtgggggc agaaacaggc gggcatggta
      301 tttcctcgtg tgtgtcaggt ttgatgccgt ctgaggcgta aggcggttcg gacggcatat
      361 gctttgtttt tattctacgc cgtactgccg acggtaggct cggacgggtt cgaggaactg
      421 tccgaattcg gggttgtttt gcaacagaat aaacaaatcg ttcaggctgg cgatgggggc
      481 gacgggcaga ccgtattgtt tttccacttc ctgaaccgcg ctcaactcac ccgtgccttt
      541 ttccatgcga tcgagcgcga tggcgacacc ggcgggggtt gcgccctccg cttcaatcag
      601 cttgatcgat tcgcgtacgg atgtgccggc ggaaatcacg tcgtcgataa tcagcacgcg
      661 gcctttaagc ggcgcaccga ccaacacgcc gccttcgccg tggtctttgg cttctttgcg
      721 gttgtaggca aacgggacgt tcacgccttt ttccgccagc atcatcgcgg ttgccgccgc
      781 caaaataatg cctttgtagg cggggccgaa cagcatatcg aatcggatgc cgctttcaat
      841 gatggattgt gcgtaaaatt ttgccagttg cagcgtggac aagccgtcgt taaagaggcc
      901 ggcattgaag aaatagggcg accgccgtcc ggctttggtg gtaaattcgc cgaatttcaa
      961 aacattttgg gcgagggaga atttgaggaa atcttggcgg aaatcggtca ttttgtgctt
     1021 tctgtcagat attgggacgc agttgcgatt ctaccgcccc gtgcggtgcg cttcaactgc
     1081 cgccgccttg ccgcaaggcg cgtttcaact gtttcaacac ctgccaggcg cgggctttaa
     1141 gttcgggttg gcgcaacagc cgggcgggat ggtcgatgat gaagaaggga cggctgccgc
     1201 acaaagtttc aatcatcgtt tgccgttcag gctggacaaa agcctgtccg aggaatagga
     1261 cggcgggggc gcggcagccg tcgagttcct gcatgacgga aaccgtcgcg gtttcgattg
     1321 ccgcttcaga cggcatcggg ttgccgacgg cggcggtttt cacccaacag gttttgtgga
     1381 cataggcggc atccagtcct acggctttga gtatgttgtc aagcagaaca cccgctttgc
     1441 cgtagaacag ttgcccgtaa accgcatcct caatcggtgg gcaaaggctg acgacggcaa
     1501 gtttggttat gcccgaagcg gcgggaacgg gggcgatgcc gtctgaaagg ccgggcgggg
     1561 gcgtttcggt ttcaggcgcg ggtttgcgcg tatgtacggc ggcggtttcc aacgctttca
     1621 tcgtttcgag ccgcgcctga ccgttatggg gttgggaagg gcggatcggg gcggcgcgga
     1681 cggtttgagg acgtgcctgt gccggggttg cgggtgtgtt tttgggcggc aggacggcgg
     1741 cggcctgttt cagccacatc gggcctaaac ccaaagcttc gtgcaggtgg aggtagcgcg
     1801 cgcttaacat attttctcca ttaagacagc atcttcggtt ttaccgtcgg ctgtacggta
     1861 atagtttttc cgcctgcccg catcggtaaa gccgtgcgcc gcgtacagtg cctgtgcggc
     1921 ggtgttgcct gcacggactt cgagcagcag gcgttgcgtg tcttcgggca gatgtgcgaa
     1981 ccaatattcg agcagggcgg acgcaacgcc acggcggcgg cattcgggcg cggtggcaat
     2041 caggtgcagt tcggattcgt cgggcaggtt ctgccaaacg ataaaggcgg caatcccgcc
     2101 gtctttttcc gcgaggaaaa cctgttcgga cggcgaaacc aatgcggact caaattggcg
     2161 ttgcgtccac gcggacgggt tgcagacggc atcgagcgcg gcgagtgcgg cgcagtcgga
     2221 cggtgaggcg cggcggatgt tcatgttcgg gctttccgtt ccgcctgttc tttggcggtt
     2281 agggcgattt tgttgcggac gtagagcagt tcggagtgtg cagcagcgac ggcgggaaaa
     2341 ccgccttccg ccgccagatt gaggaagtcg gcggcggtcg gcatatcggg tttgcctgaa
     2401 aacggcggcg tttcttccaa cgcgaacgcg ctgcctatgc cgtctgaaaa ggcacatccc
     2461 tccggcagcc ggatgtctgc cgcccgcccg acctgataat cgctcaaacg gcggcggttc
     2521 agcgtgtcga accacgcata aaacacttcg cccatacgcg cgtccgcagc ggcgagtatg
     2581 cagctttgcg gcggcggcag cgaggcggcg gcatcgagcg tggggatgcc gattaaaggc
     2641 gtattgaatg gcgttgccaa accttgcgcc acgccgatgc cgatacgcag tccggtaaac
     2701 gcgccgggac ctttcgcata aacaatcgcc cccaaatcgg cggcggtaat gcccgcattt
     2761 cggaataggg tgcggatttc cggcaggatc agttcggact ggcggctgcc ggcctcctga
     2821 tggaacagga gggtttcgcc gtcggcgcgc agcgcgagcg acaaatagga agttccggta
     2881 tcgacggcga ggacggggcg gttgaaatcg gcttgcatgg tgtggttctc gttggttcag
     2941 acggcattat atagtgaaac cggcttgcct gccgtgccgt cgtgtcctag ggcagtatgg
     3001 cgcaaaaatg ccgtccgaac ggtaaactat cgtgttcgga cggcattttt caaatgctac
     3061 tgtttgccgg cgatgccgat ttcgtgaacc ttttccctta tcttcacggt tgccgagccg
     3121 gcgatttctt gggcgcggtc gccgaaaagg gcgaggtggt aagtgccttt ttcttcgccg
     3181 ccgtagcgcg tgtcgcccaa aatgacggcg tgtgattttt catctgcttt gagttcggcg
     3241 gaggcaagct cgacattctg ctcgggcgtt ttcaggtgtt cgattctgcc gtaaccctgt
     3301 tttttggtaa aatcaatgga gtagtgcagc ctgccgttcg ggtcgtcgga gctgaatgct
     3361 ttgccgtgat actcggcttt gccgtcaggc agttggttga aggcggtatg ttctccgccc
     3421 aaaccgctga caaggaagga gcgttggttt atcaggctgt cgattttgtc ggggttgttg
     3481 attttttcaa tctgtagggc aacgacggcg gagtggttct gtttgtatat ttgaaattcg
     3541 ccgcttgcca gcgtgatggt ttgtccgtcc acttcgattt gacggataaa gtcgaagcgg
     3601 ctgaccttgt cgttcttcaa tttgcccgta ttgaggctgt cgccgtttcc ataagttttt
     3661 tccgcacctt gtgccgccag cttcagtttc tcgtttttcc tgacggactg atccagcgtc
     3721 aaagactgca aacttttgtc tttatggtcg agcggtgtgg ttagtgcatc ggcaagcccc
     3781 gcgccgatgt cggcggcgac accgccgcct ccgctgctgc aggcggtcag aatcagggcg
     3841 gcggtcaaag aaaggcagca gaaggcagtt cggttcacag gtttgctcct agtcatacgc
     3901 agaatagata atatataaac attttggtta tggtatcttt ttttgcatac tgcatcaatg
     3961 aggcaggtca aagaagcaaa aatcaaatgc cgtccgaaca acggttcaga cggcattttg
     4021 tttacaagca acctgttatt tgacgatttg gttcaattcg cccttggcat aacggcttgc
     4081 cattttttcc aaggaaaccg gtttgatttt gcctgcctga ccttcgcaac cgaacgcaag
     4141 atagcggtcg aggcagattt gcttcatcgc ttcaatggtt ttgctcaggt atttgcgcgg
     4201 atcgaagtcg gacgggtttt cggcaaggta gcggcgtacc gcgccggtgg aagcaaggcg
     4261 caagtcggtg tcgatgttga ctttgcgcac gccgtgtttg atgccttcga cgatttcttc
     4321 aaccggcacg ccgtaggttt cgccgatatt gccgccgtat tcgttgatga ctttcagcca
     4381 ttcttgcgga acggagctgg agccgtgcat cacgatgtgt gtattgggca gggcttggtg
     4441 gatttctttg atgcggtcga tacgcaacac gtcgcctgtg ggcggacggg tgaatttgta
     4501 cgcgccgtgg ctggtgccga cggcaatcgc caatgcgtca acgccggtat ctttaacgaa
     4561 acgcacggca tcttcgacgc tggtgagcat ttggtcgtgg gaaagtttgc ccactgcgcc
     4621 tacaccgtct tcttcgccgg cttcgccggt ttcgaggttg cccaacacgc cgatttcgcc
     4681 ttcgacggat acgccgcaag cgtgggagaa attaaccacg gtacgggtgg cgttgacgtt
     4741 gtattcataa gaagaagggg ttttgccgtc ttccatcagc gagccgtcca tcatcacgga
     4801 ggaaaagccc agttggatgg agcgttggca cacgtcgggc gatgcgccgt ggtcttggtg
     4861 catcacgacg gggatgtgcg gaaattcttc gacagccgcc agaatcaggt ggcgcaaaaa
     4921 cggcgcgccc gcatatttgc gcgcacctgc actcgcctgt acgatgacgg gcgcgttgac
     4981 ttggtcggcg gcttccataa tggcgcgcat ttgttcgagg ttgttgacgt tgaacgcggg
     5041 caggccgtag ctgttttcgg cagcatgatc aagcagttgg cgcatggata cgagtgccat
     5101 ttgtgtctcc ttgggcaata ggtaaataag gcggattata atgttttttg cggcaaaaaa
     5161 ccataaacgg ctcattgatt ttatgttaac gataacggcg ggcggacggg tcggattttg
     5221 ggcggttcgg ggttttggtg tgtcgtttat gataatgttt tcactgtttt tttgatattt
     5281 gtgtggggcg gttatggttt tggacgggtt tgcggcgcat tttgacgctt atttggaaaa
     5341 catcgtgcgc gagggcaagt cggagcacac ggtggcggca taccggcgcg atttggaaga
     5401 actgtttgcg ctgttggcac aaatgccgtc tgaagatgaa ggcggcgtgc cgcaggactt
     5461 gtcgcggcgc gattttacgg cggcgttgcg gcggctgtcg cagcgcggtt tgaatgcgcg
     5521 gacgctggcg cgcaagctgt cgtcttggcg gcagtattgt gtttggctgg tggaacgcgg
     5581 tctgctgcat accgacccga ccgccgacat caaaccgccg aagcagcccg agcgcgtacc
     5641 caaagccctg tcgcaggaat ggctgaaccg gatgctggat ttgcccgtgg acggcggcga
     5701 cccgctggcg gtgcgcgatc acgccctgtt cgagctgatg tacggcagcg gtttgcgcgt
     5761 gagcgagata cacggcttga atgcagatga tgtctatttg gacgaggcgt gggtacacgt
     5821 taccggcaaa gggcgcaagc agcggcaggt gccgctggtc ggcaaaagcg tggaagccct
     5881 gaaaaactat ctgccgctgc gtcagacggc atcggacggc aaagccctgt ttaccggcag
     5941 gaacggcacg cgcctgagcc aacgccaaat ccaaaaacgt ttggcgcaat gggcggcgca
     6001 aaacggcgac ggcaggcacg tttcgccgca tatgatgcgc cacagctacg ccggacacct
     6061 gttgcaggct tcgcgcgaca tccgggcggt gcaggagctg ctcgggcaca gcagcctttc
     6121 gaccacgcag atttacacca aactcgattt cgaccacatc gcccgcctgt atgacgaagc
     6181 ccacccgcgc gccaagcggc aggacgaatg acatacggca aaatcagccg tcagccgcac
     6241 gctcttgata tataattggt cgttgcacct ggacgacaca taaaaaagac acaccatgaa
     6301 cccaagcccc ctactcgacc tgattgacag cccgcaagat ttgcgccgtc tggacaaaaa
     6361 acagctgccg cgccttgccg gcgagttgcg cacctttctg ctggaatctg tcgggcagac
     6421 cggcgggcat ttcgccagca atttgggcgc ggtcgaactg accatcgccc tgcactatgt
     6481 gtacgacacg cccgaagaca agctggtgtg ggatgtcgga caccaaagct atccgcacaa
     6541 aatcctgaca ggcaggaaaa accagatgca caccatgcgc caatatggcg gtttggcggg
     6601 ttttccgaaa cgttgcgagt ccgagtacga cgcgttcggc gtggggcatt cctccacctc
     6661 catcggcgcg gcgttgggca tggcggcggc agacaaactc ttgggcagcg accgccgcag
     6721 cgtcgccatc atcggcgacg gcgcgatgac ggcggggcag gcgtttgaag ccttgaattg
     6781 cgcaggcgat atggatgtgg atttgctggt cgtcctcaac gacaacgaaa tgtcgatttc
     6841 ccccaacgtc ggcgcgctgc cgaaatacct tgccagcaac gtcgtgcgcg atatgcacgg
     6901 cctgttgagt accgtcaaag cgcaaacggg caaggtatta gacaaaatac ccggcgcgat
     6961 ggagtttgcc caaaaagtcg aacacaaaat caaaaccctt gccgaagaag ccgaacacgc
     7021 caaacagtca ctgtctttgt ttgaaaactt cggcttccgc tataccggcc ccgtggacgg
     7081 acacaacgtc gaaaatctgg tcgatgtatt gaaagacttg cgcagccgca aaggccctca
     7141 actgctgcac gtcatcacca aaaagggcaa cggctacaaa ctcgccgaaa acgaccccgt
     7201 caaataccac gccgtcgcca acctgcccaa agaaagcgcg gcgcaaatgc cgtctgaaaa
     7261 caaacctgcc gccaaaccga cctataccca agtgttcggc aaatggctgt gcgaccgggc
     7321 ggcggcagat tcccgactgg ttgcgattac ccccgccatg cgcgagggca gcggcttggt
     7381 tgagtttgaa caacgattcc ccgaccgcta tttcgacgtc ggcattgccg agcagcacgc
     7441 cgtaaccttt gccggcggtt tggcttgcga agggatgaag cccgtcgtgg cgatttattc
     7501 caccttttta caacgcgcct acgaccaact ggtgcacgac atcgccctgc aaaacctacc
     7561 cgttttgttt gccgtcgacc gcgcgggcat cgtcggcgcg gacggcccga cccacgccgg
     7621 tctgtacgat ttgagctttt tgcgctgcgt gccgaacatg attgtcgccg cgccgagcga
     7681 tgaaaacgaa tgccgcctgc tgctttcgac ctgctatcag gcggatgcgc ccgccgccgt
     7741 ccgctatccg cgcggcacgg gtacgggcgc gccggtttca gacggcatgg aaaccgtgga
     7801 aatcggcaag ggcattatcc gccgcgaagg tgggaaaacc gccttcattg ccttcggcag
     7861 tatggtcgcc cccgcattgg cggttgccga aaaactgaac gccaccgtcg ccgatatgcg
     7921 cttcgtcaaa ccgatagacg aagagttgat tgtccgcctt gcccgaagcc acgaccgcat
     7981 cgttaccctt gaagaaaacg ccgaacaggg cggcgcaggc ggcgcggtgc tggaagtatt
     8041 ggcgaaacac ggcatctgca aacccgtttt gcttttgggc gttgccgata ccgtaaccgg
     8101 acacggcgat ccgaaaaaac ttttagacga tttgggcttg agtgccgaag cggtggaacg
     8161 gcgtgtgcgc gcgtggttgt cggatcggga tgcggcaaat taagccgcct ggccgcgcca
     8221 tcgtctgccg atacaaggca aaatgccgtc tgaaacgctt cagacggcat tttttcggcg
     8281 taagggttta ggcttcgaca actttgccgc gcagggagaa ggtgtaggcc tcggtgattt
     8341 ccaaatcgat catttggtta atcatgtcgg gcgtgccggt aaagttgacg acgcggttgt
     8401 tggcggtgcg ggcttggagc tggtcggggt cttttttgga gatgccttcg accaggcagc
     8461 gttgaaccgt gccgatcatc gtttggttga tgcgcgcggt ttcggcttcg atgacttcgt
     8521 tcaaggcttc gaggcggcgc actttttctt cgtgcggcgt gtcgtccggc aggttggcgg
     8581 caggcgtgcc ggggcgcgga ctgtaaataa acacgaagct caagtcgaag gcgatgtctt
     8641 tcaccagttt caaggtttgc tcgaactcgc gttcggtctc gccggggaag ccgacgatga
     8701 aatcgctgct caggcacaaa tcaggacgga tggcacgcag tttgcggatg atggatttgt
     8761 attccaaagc ggtgtagccg cgtttcatcg cgctcaatac gcggtcggaa ccgctttgaa
     8821 tcggcaggtg caggtgggaa accaatttgg gcaggtcgcg gtagcactcg ataatcgagt
     8881 cggtaaactc gcgcgggtgg ctggtggtga agcgcatacg ttcaatgccg gggatttcgt
     8941 ggacgatgcg cagcagggtg gcgaagtcgc agatttcgcc gtcgtccatt tcgccgcgat
     9001 aggcgttgac gttttgtccc aagaggttga tttctttcac gccttgctgg gcaaggttgg
     9061 cgatttctgt caatacgtcg ttgagcgggc gggagaattc ttcgccgcgc gtgtagggga
     9121 cgatgcagaa ggagcagtat ttggaacagc cttccataat cgatacaaat gccgcgccgc
     9181 cttcgacgcg ggcgggcggc aggtggtcga atttttcgat ttcggggaag gaaatatcga
     9241 cttgcgacag cccgctggtt tctttgtcca caatcatttt tggcaggcgg tgcagcgttt
     9301 gcgggccgaa aaccacgtcc acataaggcg cgcgtttgat gatgttttcg ccttcttgcg
     9361 aggcgacgca gccggcaacg ccgatgatga ggccggggtt tttttctttg agcggacgca
     9421 cgcgccccaa atcggagaag actttttctt gcgctttttc gcgcacggag caggtgttga
     9481 acaagatgat gtcggcttcg tcggcttggg taacctgttc gatgccgccg tgttcttcgg
     9541 cgaggacggc gagcattttg tcgctgtcgt attcgttcat ctggcagccg aaggtgcgga
     9601 taaatacttt tttcatggtt tgtgtctttc tcaggcagcc gtaatcgcgg ggctgattgt
     9661 tgttggaatg aaaaaatttc agacggcatg acgatgccgt ctgaaaatcg gtgcggatta
     9721 tagcacgatg tgggttttgt aaacagaata ttgttttaaa atatgaattt aatcggtcgg
     9781 gacggctata taatgtttgg ctttaatggg aggtgtgtat gaaaccggct gtgtgggcgg
     9841 cattgctgct gtgtgcgtgt accagcaatt tcggcgacag ggaacatcag ttcctgcgtt
     9901 atagtggatt aacaaaaacc agtacagcgt tgcctcgcct tagctcaaag agaacgattc
     9961 tctaaggtgc tgaagcacca agtgaatcgg ttccgtacta tttgtactgt ctgcggcttc
    10021 gtcgccttgt cctgattttt gttaatccac tatatcagac ggaagaggga atcgcacaaa
    10081 cggttgttaa aggcaaaacg acccgggcgg aggtagaggc acgtttcggg aagcgcaacc
    10141 ctttcggttg ttatgcctat cacgaggtca gcctgccgat ttataatttt ttgccgacca
    10201 atttcattta tatgaaatca gaacgccgac attgggagtg gtgtgtggat tacgactggg
    10261 aaggagttgt ccgggactac cgctttacac ataaagtgga aaaagacgag cgttccgtca
    10321 tccgggatgc ggttggcgtc atccgcaaag aagcaggcaa atccttgtcg caacctgaaa
    10381 aatgataaaa tgggactttc tgcttctaag cccgaaacct gccgttcaga cggcatttga
    10441 ggataaatat gaaccgtaac gaaattttat tcgaccgcgc caaggcggtc atccccggcg
    10501 gcgtgaattc ccccgtgcgc gcattcggca gcgtcggcgg cgtaccgcgc ttcatcaaaa
    10561 aagccgaagg cgcgtatgtt tgggatgaaa acggcacgcg ctacaccgac tatgtcggct
    10621 cttggggccc tgcgattgtc ggacacgcgc accccgaagt cgtcgaagcc gtgcgcgaag
    10681 ccgcgttggg cggtttgtca ttcggtgcgc ccaccgaggg cgaaatcgtc atcgccgaac
    10741 aaatcgccga aattatgccg tctgtcgaac ggctgcgcct cgtcagctcc ggcacggaag
    10801 cgacgatgac cgccatccgt ctggcacgcg gttttaccgg ccgcgacaaa atcatcaagt
    10861 ttgaaggctg ctaccacggg cattccgaca gcctgctggt gaaagccggc agcggcctgc
    10921 tgacgttcgg caatccttct tccgccggtg tgcctgccga ctttaccaaa cacaccttag
    10981 tcctcgaata caacaacatc gcccaattgg aagaagcctt tgctcaaagc ggcaatgaca
    11041 ttgcctgtgt gattttggag ccttttgtcg gcaatatgaa ccttgtccgc ccgaccgaag
    11101 ccttcgtcaa agccctgcgc gaattgactg aaaaacacgg cgcggtgttg atttacgacg
    11161 aagtgatgac aggtttccgc gtcgcactcg gtggcgcaca atcgctgcac ggcatcacgc
    11221 ccgacctgac cacgatgggc aaagtcatcg gcggcggtat gccgcttgcc gcgttcggcg
    11281 gacgcaaaga cattatggaa tgtatttccc cactgggcgg cgtgtatcag gcaggtacat
    11341 tatcaggcaa cccgattgcc gtcgccgccg gtttgaaaac gctggaaatc atccgccgcg
    11401 aagggtttta tgaaaacctg acggcgcgta ccgaacagtt ggttcaaggt tttcagacgg
    11461 cagcggatgc ggcgggcatc gagttcaccg ccgacagcgt gggcggtatg tttggtttgt
    11521 attttgccag ccatacgccg caaaactacg gcgacatggc gcgttccaat attgaaggct
    11581 tcaaacagtt tttccacggc atgctcgacc gcggcattgc cttcggcccg tccgcttatg
    11641 aagcaggttt cgtttctgcc gcgcatacgc ccgagctgat tgatgaaacg gttgcggttg
    11701 cggttgaagt gttcaaggcg atggctgcat gatgttttga cggacagggt ttccctgttc
    11761 aatttgtttg gcagattgaa gtaagaatgc acaccgccgt cattcccgcg caggcgggaa
    11821 tccagacctt tcagtttctg taatgattga aaataacgtg ccgaaatcag ccgcacccgg
    11881 caggaagccg ccgccacctg aaacaatgcc gtctgaagcc ttcagacggc attttatcgg
    11941 aagcgcatca gaaaaaacgg atagcgacat atgcggtaaa agcaagggca attacataga
    12001 taaacccctt tataaattca aaagtctcat ctatatcgct atatttttct ttcagttcgt
    12061 cagattttcg ataacgtttc attttcaaga ccacttcatg accaacaagc ccgaccttcc
    12121 ggattcccgc ctgcgcggga atgacgggcg tgtatatttt tgatttcaat ctgctgtaaa
    12181 aatgccgtct gaaatgcagg atttgcgctt cagacggcat tgtttgtttc ttattgcgct
    12241 tcggctctcg gggcggaaat cagaaagtgt tcgcggtagt ggcgcatttc ttcgatgctc
    12301 tccaaaatgt cgtccaatgc cttgtgcgaa ccgcgtttga ccacgctttt ggcaacgggc
    12361 ggattccagc gtttggcaag ctctttgagc gtggaaacgt cgaggttgcg gtagtggaag
    12421 tagttttcca gtttcggcat atatttgacc ataaaacgcc ggtcttggtg gatggagttg
    12481 ccgcacatcg gcgtggcgcg ttcgggtacc cattccgaca taaagtccag cagtttctgt
    12541 tcgacttcgg cttcggtatg cgacgattcg cgtacgcgct gcgtcagccc cgtcctaccg
    12601 tgtgtggcgg tgttccactc gtccatattg tcgagcagct cgtcgctttg gtggatggcg
    12661 taaacttcgg attgcgccaa tacattcaaa tccgagtcgg taataatcat cgcgacttcg
    12721 ataatgcggt cggtttcggg attaagcccc gtcatttcca tatcgagcca gcataggttg
    12781 tttttatcct gcatgatgtt tcctttgctt gtcagcgttt tgtcccgctc aagcgcgccc
    12841 agctttcttc ggtttccgcc gggtcgagat cgaaccattg gctgtaaatg ccgccgagtt
    12901 cttcggcttg ttcgtccaac aaaccggata acacgatgcg gccgccttgt ttggtgcggg
    12961 cggcgagcat ttcgccgagc atacgtaaag ggttggcgag gatgttggcg acaactacgt
    13021 cgaattgccc ttgaggcaga ccgtcgggca ggaagaattg tgcatcgacg ttgttctgtt
    13081 cggcgttgtc cttgccggcg cggacggctt gttcgtcaat atccacgccg acggcagaac
    13141 ctgcgccgag tttgagggcg gcgatggtca ggatgcccga accgcagccg tagtcgagga
    13201 cgctttcgcc gtttttgagt tgcgtatcca gccatttgag gcagaggcgc gtggtcgggt
    13261 ggctgccggt gccgaaggcg aggccgggat cgaggcgtag gttgacggca gtgccttcgg
    13321 gggcttcgtg ccaagagggg gtaatccaca ggcgttcgga aattcggatg gggtcgaatt
    13381 gcgcttgggt caggcgtacc cagtcttggt cttcgaggat ttcgccggtg tatgccaagt
    13441 cttttaatcc gcattcttgt gcggcggttt ggatgatggc ggcggcttcg tcgtgttcgc
    13501 cgaacagggc gatgactttg ctctgctgcc agatttgttc ggcgggcata ccgggttcgc
    13561 cgaaaatcgc ctgttcgttt tgcgtgccgg cgtaggcatc ttcgatggcg gcggagagtg
    13621 cgccgtgttc catcagcgcg tcggcgaggc gttcggcgac ggcatcgttg acgttgacgg
    13681 tgatttgttg gtagggcata acgggctttc ttaacagacc ttcggaatag ggtcgtactg
    13741 tataagggga tgggtgtgta acggaaatgc cgtctgaaaa cggacaaact gtttcagacg
    13801 gcatatcggg gacggcttat ttgtcctgtt tggctttgcg atcttccagc cagtgttcca
    13861 aatagtggat gctgacgccg cctttttgga aacccgcatc ggcgaacagg tcgcggtgaa
    13921 gcggcgtatt ggttttgatg ccggttaccg ccagctcggc gagtgcgacg cgcattttcg
    13981 ccattgcctg ttcacgcgtt ttgccgtgta cgcagatttt gccgatcagg ctgtcgtagt
    14041 acggtgggat gcggtagcct tggtaaatgt ggctgtccac gcggataccg aagccgccgg
    14101 gcaggtggca gctttcaatc gggcccgggc tggggatgaa gttgtatggg tcttcggcgt
    14161 tgatacggca ctcaaacgcg tggccttcga cttgaatatc cttttgtttg tattgcaaag
    14221 gcaggccggc ggcgatgcgg agttgctcct gcacaatgtc cacgccggta atcagctcgg
    14281 taaccggatg ctcaacctga acgcgcgtat tcatctcgat aaagaaaaat tcgccgtctt
    14341 cgtacaggaa ttcaaacgta cctgcgccgc gatagccgat gcgtttgcag gcgtcggcac
    14401 aggcgttgcc gattttggcg cgttcttttt cagtgatgaa cggagccggt gcttcctcga
    14461 tgactttttg gtggcggcgt tgcagcgaac agtcgcgctc ggcaaggtag atggcgttgc
    14521 cgtgttcgtc ggcaatcact tggatttcga cgtggcgcgg acgttgcagg tagcgctcca
    14581 tgtaaaccat cgggttgccg aatgccgcgc ctgcttctgc cttggtcatt tcgacagatt
    14641 ggaggaggtc ttcttttttc tcgaccacgc gcataccgcg accgccgccg ccgccagagg
    14701 ctttgataat gacgggataa ccgactttat cggcgatttt gaggatttct tcgccgtcgt
    14761 cgggcaatgc gccgtcagaa ccggggacgc agggtacgcc tgccgctatc atcgcgtgtt
    14821 tggcggagac tttgtcgccc atcaggcgga tggtgtcggg tttcgggccg ataaaggtaa
    14881 agccggactg ctcgacctgt tcggcgaaat cggcgttttc ggcaaggaaa ccgtagcccg
    14941 gatggacagc gtccgcgcag cttacttcgg cggcggcgat aatggcgggg acgttaaggt
    15001 agctttgcgc ggaagcggca gggccgatgc acacggattc gtcggcgagt ttgacgtgca
    15061 ggctgtcttt gtcggcctcg gaatgcacgg cgacggtggc aatgcccatt tcgcggcagg
    15121 cacggagtac gcgtaatgcg atttcgcctc ggttggcgat taaaactttt ttcagcatga
    15181 tgactgttcc tgtggttccg gcaacccgtc cgtaaaaaaa aaggtgcggg aacgccgaag
    15241 ggggaaagca tttcagacgg catcggaagt ttatgccgtc tgaaaacagg attatccgat
    15301 gatgaagagc ggttcgccga attcgacggg cgtaccgttt tcgaccagaa tttctttgac
    15361 cgtgccggat ttttcggctt cgatttcgtt catcagcttc atcgcttcga tgatgcacag
    15421 cgtgtcgccg gctttaacct gttggccgac ttcgacaaaa ggcgcggcat tcgggccggg
    15481 tgcgcggtag aacgtgccga ccataggcga tttttgcgcg tcggacaaat cgcgggcggc
    15541 aggtgcggcg ggcgcggatg ccgcaacggg tgcggcggca ggcgttacgg ccggcgcggc
    15601 ggcaggtacg ggcgcggcgt aaacgggtgc ggcggcgatg gttcgggtga tgcggacttt
    15661 ttcctcgcct tcggttactt cgatttcggc gatacccgat tcttcaacca aatcaatcag
    15721 tttttttaat ttgcgcaaat ccatttctgt tcctttaaag gctgccggtg ttccggcggg
    15781 ttgttgcgtt ggtttttcag aaaacagccg gcttgcggca acggcgcaaa ccgggcggaa
    15841 tggtgttcgg atacggtttt cctgtggtgg aaaacaaccg tgagaatgtg tttattttcc
    15901 cgaagttgtc ggtaaatgtc cagtaaaata tcaaaaaacg gcggtttttg ggggaaatgt
    15961 gcaggaagct tgattttgcg cacaagatgc cccgggtcaa gagtgtttat tctaatctgt
    16021 tggtttttcg gacaaagatg ccgtctgaaa aagggctaaa gtgcgtataa tggcggcttg
    16081 cccgaacgag agtgtaaaaa tggatatttc agattttgat tttaccctgc ccgaaaagct
    16141 gattgcccag catccgcccg aagtgcgcgg cagcagccgc cttttggttg cgttgcccga
    16201 tatgccgctg caagaccggg tgttcggcga tttgccggat tatgtcgagg cgggcgacgt
    16261 tttggtgttc aacaacacca aagtcatgaa ggcgcggctg tttgggcaga aagacagcgg
    16321 cggcaggatc gaagccctga ttgagcgcgt gttggacaac cataccgcac tggcgcacat
    16381 ccgttcgtcc aagtccccca agcccggtat ggggctggtg tttgaaggcg gcatccgtgc
    16441 cgtgatggtc gggcgtgagg gcgaactgtt ctgcctgcgt tttgaaggcg gtcaaaccgt
    16501 ttacgaactt ttggaacaga acggccattt gcctctgccg ccttatatcg aacgtgccgc
    16561 cgacgcggac gacgacagcc gttatcaaac cgtttatgcc aaatatcagg gcgcggtcgc
    16621 cgcgccgacg gcgggcctgc attttacgga agaacttttg caccgtctga aagacaaagg
    16681 cgcggtaacc gcagaagtaa ctctgcacgt cggtgcgggg acattccaac ccgtgcgtgt
    16741 ggaaaaaatc gaagaacaca aaatgcacag cgaatggttt gaagtgccgt ctgaaaccgc
    16801 cgccgccgtt gaggcggcaa aagcccgggg gaacaaagtc tgggcggtcg gcacgacttc
    16861 catgcgcgcc ctcgaatctg ccgcgcgtgc gacgggtcgt ctgaaagcgg ggcagggcga
    16921 caccgatatt ttcatcacgc cgggctaccg ttttaatgtt gccgacaggc tggttaccaa
    16981 tttccatctg ccgaaatcga cgctgctgat gcttgtcagc gcgttttcgg gtatgggtca
    17041 tatccgcgcc gcgtatcgtt atgcggtcga acgcgaatac cgtttcttca gctacggcga
    17101 tgcgatggtt ttggggcgga acgaaggggt ggtacgttag aacagcctca agtctattgg
    17161 gggaagacaa gtgccgtctg aacggatgtt cggacggcat tcttttgttg atttgaatga
    17221 aaggaactgc atgacatata gtggattaaa tttaaatcag gacaaggcaa cgaagccgta
    17281 gacagtacaa atagtacggc aaggcgaggc aacgctgtac tggtttttgt taatccacta
    17341 tagattcagg cgcgagaggc gagaaactca gtcattgttg atgacgcgca atacgttaaa
    17401 attcattccg ttttggtcgt ataaacatat tacatacgcc atttttttgt attcaaggct
    17461 gcctgaaaac agtgggcaag aatatctaac ccaacgaaaa gctgaaaaag caacaaaaaa
    17521 taatctgcac cttagtcggt tggttagtcc aaccttaggg gtgcagacca ttcaatcttt
    17581 caggctgcct ttgtttgttt ataagataaa tttttagccg aacacttttt ccaagtgtgc
    17641 ctgataatct gccaagtatt tttccacttg tggattttta accacatcgt tacataagaa
    17701 tgtcggcagg cgggtcatac ccaaaaactc gttggctttg tggaagtgca tatacaaaac
    17761 atcaacgcct ttgccttcaa agaaatcgcc ttcgcgggta aacgcctcaa tcggcgcatt
    17821 ccaagtcagt gaaagcatat gttttttgcc ttgcaacaag ccgcctgtgc cgtagccctc
    17881 agtcggattg acgcggtgtc tgccgtcgct ttggtagagt ttgccgtgtc cagcggttaa
    17941 tacttcgtct atgtattttt tcactgtcca aggctcgtgc atccaccagc ccggcatctg
    18001 ccaaatcaca gcatccatcc aaacgaattt ttcgatttct gcctcaacat catagccggc
    18061 atcaatcacg gtttcttgaa cattgtgtcc gagcgcggtc aaaacttctt tcgctttttt
    18121 gtgaagcgtg cggtttaacc cgccgtgaga atgtccgaac gctttgccgc cgtctaataa
    18181 taaaatattc atttgttacc tcgtttgtga attgatgaat gtattgtgcc gttttacttt
    18241 ataatttaaa agtgcaaaaa taagaaaaca cttttgcgtc aaatgaaata atcagatgtt
    18301 ccaacacacg ggatggcaca taaagcaccg ccctgtgtgc cgtcctgatt cggaaggggt
    18361 tacacccctc ccaaataaag tctgatcctg ccgccctaaa gggcggggtt ccaaccgaaa
    18421 aggaaacacg atgaaaacca attcagaaga actgaccgta tttgttcaag tggtggaaag
    18481 cggcagcttc agccgtgcgg cggagcagtt ggcgatggca aattctgccg taagccgcat
    18541 cgtcaaacgg ctggaggaaa agttgggtgt gaacctgctc aaccgcacca cgcggcaact
    18601 cagtctgacg gaagaaggcg cgcaatattt ccgccgcgcg cagagaatcc tgcaagaaat
    18661 ggcagcggcg gaaaccgaaa tgctggcagt gcacgaaata ccgcaaggcg tgttgcgcgt
    18721 ggattccgcg atgccgatgg tgctgcatct gctggcgccg ctggcaacaa aattcaacga
    18781 acgctatccg catatccgac tttcgctcgt ttcttccgaa ggctatatca atctgattga
    18841 acgcaaagtc gatattgcct tacgggccgg agaattggac gattccgggc tgcgtgcacg
    18901 ccatctgttt gacagccgct tccgcgtaat cgccagtcct gaatacctgg caaaacacgg
    18961 cacgccgcaa tctacagaag agcttgccgg ccaccaatgt ttaggcttca ccgaacccgg
    19021 ttctctaaat acatgggcgg ttttagatgc gcagggaaat ccctataaga tttcaccgca
    19081 ctttaccgcc agcagcggtg aaatcttacg ctcgttgtgc ctttcaggtt gcggtattgc
    19141 ttgcttatca gattttttgg ttgacaacga catcgctgaa ggaaagttaa ttcccctgct
    19201 cgccgaacaa acctccgata aaacacaccc ctttaatgct gtttattaca gcgataaagc
    19261 cgtcaatctc cgcttacgcg tatttttgga ttttttagtg gaggaactgg gaaacaatct
    19321 ctgtggataa ttctataaaa acctgccata aaattgtttt tactcactta ataactttga
    19381 gaaaaaataa ataagatgat gtatagccgc ggcaatggca gtctatatgg ggagcgtgat
    19441 agggctgttc cttatgtacg gcttgtgtgt ggcaacatcg gctttccaaa tgacaaaatg
    19501 ccgtctgaaa ccgtaaaaaa aaaaaggttt cagacggcat tttcaacctg attcaggcat
    19561 cagttgcggt ttttcaaacg cccgtgcagt tcttgaacgc tgtacacgcc caagtggtcg
    19621 cggcttttcg cgccttcgct catcgcttcg ccgccggcgg tggtggtgta ttgcggcacg
    19681 cgttgctgca atgcgctttg gcggatgatg tggctgtcgg acacggattg cggatcgctg
    19741 gaaacggtat tcacgaccag tgcgatttca ccgtttttca gcgcgtcgcc gatgtgcggg
    19801 cggccttcgg ggactttatt gatggtttgg acaatcagcc cgtgttcggt caggtattgc
    19861 gccgtgccgc gcgtggcgca gatgccgtag cctaaggctt ggaagttttt ggcggtttta
    19921 atgacgcgtt ctttgtcttc ttcgcgcacg gagaggaaga ttttgccggt cgggttgagg
    19981 cgttcgcctg cgccgagttg ggctttgtag taggcttcgc cgaagcttgc gcccacgccc
    20041 atgacttcgc cggtggagcg catttccgga cccaaaatcg tatccacgcc cgggaatttg
    20101 atgaagggga acacggcttc tttaacggca tagaaatcag ggacgacttc tttttccacg
    20161 ccttgttctt tcagggaaat gcctgccata cagcgtgcgc cgactttggc gagcggcacg
    20221 ccggtggctt tggagacgaa ggggacggtg cggctggcgc gcgggttcac ttccaatacg
    20281 aacactacgc cgtcctgcac ggcaaactgc acgttcatca gtccgaccac gcccagcgcg
    20341 tacgccatcg ctttggtttg gcggcggatt tcgtcttgga tttcttcgct taaggagtag
    20401 ggcggcagcg agcagccgga gtcgccggag tggatgcccg cctgttcgac gtgctgcatg
    20461 atgccgccga taaccacatc tttgccgtct gaaacgcagt ccacatcgac ttcaatcgcg
    20521 ttgttcagga agaagtcgag caacacgggg ctgtcttcgg aaacctgcac ggcttcgcgc
    20581 atatattttt gcaactgctc ggcagagtgg acaatctgca tcgcgcgtcc gcccaaaaca
    20641 taagacgggc gcacgaccag cggataaccg atttcttcgg ctttgacgag tgcttcttct
    20701 tcgttgtggg cgatgcggtt gggcggctgg cgcaggccta agtcgttcaa cactttttgg
    20761 aagcgttcgc ggtcttcggc ggcatcgatg ctgtcggcgg acgtgccgat gatgttcacg
    20821 ccgttttcaa ccagcgcgtt ggcgagtttg agcggggttt gaccgccgta atgcacaatc
    20881 acgccccacg ggttttcggt gcggacgatt tccaacacgt cttccaatgt cagcggctcg
    20941 aaatagaggc ggtcgctggt gtcgaagtcg gtggacacgg tttctgggtt gcagttgacc
    21001 ataatcgttt caaaaccgga ttcgcgcagg gcgagcgcgg cgtgaacgca gcagtagtca
    21061 aactcgatgc cctgaccgat gcggttcggg ccgccgccga gaatcatcac ttttttgcgg
    21121 tcggaaggac gcgcttcgca ttcctcttcg taagtggaat agaggtaggc ggtttcggtg
    21181 gcgaactcgg cggcacaggt gtcgacgcgt ttgtaaaccg gatgcagctt cagcgcgtag
    21241 cggtgttcgc gaacttcttt ttcgcttacg ttcaacaatt gtgccaaacg tttgtcggag
    21301 aagcctttgc gtttcagacg gcgtagggcg gcgaaatcca aatcactcaa aatgccgtct
    21361 gaaaccgctt tttcttcctt catcaagtct tcgatttgcg ccaggaacca agggtcgatg
    21421 gcgcagattt cgtggatttc ttccagcgtg aagccggcgc ggaacgcgtc tgccacaaac
    21481 agcatacgct cagggccggg gttcgccagt tcgcggcgga tttccgcttt gtcggagctt
    21541 ctcggattga agccgcacaa gccggtttcc aagccgcgca aggctttttg gaagctttcc
    21601 tgaatcgtgc ggcccatcgc catcacttca cccaccgatt tcatctgtgt ggtcaggcgg
    21661 tcgtctgcgg cagggaattt ttcaaacgcg aaacgcggga ttttggttac gacatagtcg
    21721 atggacggct cgaacgacgc gggggttttg ccgccggtga tgtcgttgcg caactcgtcc
    21781 agcgtaaagc cgaccgccag cttggccgcc accttcgcaa tcgggaagcc cgtcgctttg
    21841 gaagccagcg cggacgaacg gctcacgcgc gggttcatct caatcacaat catctcgccg
    21901 ttttcagggt tcatcgcaaa ctgcacgttt gagccgcccg tgtccacgcc gatttcgcgc
    21961 aataccgcca acgaagcgtt gcgcatgatt tggtattcct tgtccgtcag cgtttgcgcc
    22021 ggcgcgaccg taatcgagtc gcccgtatgc acgcccatcg ggtcgaagtt ttcaatcgag
    22081 cagatgatga tgcagttgtc gttcttgtcg cgcactactt ccatctcgta ctctttccag
    22141 ccgagaacgg actgctcaat cagcagctcg tgcgtgggcg aggcatcgaa accgcgttcg
    22201 caaatcgcca aaaactcgtc tttattgtag gcaatgccgc cgcccgaacc gcccatcgtg
    22261 aaagaaggac gaatcagggt agggaagccg acctgttcct gcgccgccaa agcttcgttc
    22321 attgtgtggc agacaaaaga tttcgggcaa gacaaaccga ttttttccat cgcctcttta
    22381 aagcggccgc ggtcttctgc tttgtcgatg gcgtcttccg tcgcgccgat taattcaaca
    22441 ttgtatttcg ccagcacgcc gttgcgcgcc aaatccagcg cacagttcag cgcagtttga
    22501 ccgcccatgg taggcagaat cgcatcgggc cgctctttgg caataatttt ttccaccgtc
    22561 tgccacataa tcggctcgat gtaggtaaca tccgccattt cggggtcggt cataatcgtg
    22621 gcggggttgg aattcaccaa aatgacttta tagccttctt cacgcaaggc tttgcaggcc
    22681 tgtgcgcccg aatagtcaaa ttcgcaggcc tgaccgataa cgatagggcc ggcgccgatg
    22741 ataaggatgg attttaggtc ggtacgtttg ggcatgatgg gtctttctat gaaatcaaat
    22801 gtttagctaa aaatttattg ctgattttga ttggctttta attgctctac gacagtattg
    22861 gcaatctctt ttcctgatgg ggctgtaatt gtgtaataaa agctaatact gcctatgaag
    22921 aaactgataa tggctatgat ataggctata taactttgtg ttttcatttt tttgtgatca
    22981 tgtttgatct gatttaattc ttttaattca gaaataattg gagttaataa atgtttttga
    23041 ctttcagatc catgcgtttc caaaagttca tttattccta ttagtgttgg ttttagttcg
    23101 tctgagcagc catcaaaagg ttcttcttgt tggatttcct tttgtaactg tctaactaaa
    23161 tttaaattta attcatcagt gtaatatagt tgcttaataa tttttctggc agcaaaatta
    23221 ttaaggttta ctgcttctgt catttgtttt atatcattaa gatctaggtt attgtgatta
    23281 tttttaatat atcaattatt ctagatttaa atttcttttt ctttatattc tctaaatata
    23341 gctgaattgg aataaaaaca attataaaga gcaaaagaaa tatatatgtt agtgccatag
    23401 cccatgtggc aattatattt atcatttatc aatatcttcc atttggttta tatattgtct
    23461 cataataagc aagccgtagc tcgcatgcag ggtgtgtgcg gtacgcacgc gttctccatt
    23521 ttccctgcaa ccccaaccca ccgtgtgcgt gccttgcggc acacacccta ccgatgggtt
    23581 caaaggtcgt ctgaaaaaac gctcgcggcg tttgttccat ctgccttgcg ataaaggctg
    23641 cctgaaaaat tcccgctgtt gatatttcgg gcattctttc tcaaaccgcc tgcaaccgca
    23701 aaatccgctg caacctgccc cctcccccgt gggggagggt tggggagagg gcattccccg
    23761 aatttcggca acctttccca acaactcaac caccgaaata caagccttgt ggcttgttgc
    23821 cctctctcta gctctctccc acgggagaga ggacggagtg gctgtagggc taagggttct
    23881 gcaaggaaac aggttgtgca ggttgctttt tgcttttcag acgacctgaa atcaacggta
    23941 aatccaagtc gcttttcaaa ccgcctgcaa ccgcaaaatc tgctgaaacc tactccctcc
    24001 cccgtggggg agggctgggg agagggcatt ctccgaattt cggcaacctt tcctaacact
    24061 ctaaccgcca agacacaagc cttgcggctt gttgccctct ctctagctct ctcccacggg
    24121 agagaggatg gggtggctgt tggggctaag gtttctgtaa actaatcagg ttatgcaggc
    24181 tgctttttgt ttttcagacg gcctttataa atgctcaatt cagtcggctt tatcctatta
    24241 ttttcaataa tccaatcaaa atcagccatc tgctatcgtg cagcttgctt ttccaattct
    24301 tgcaacacga gcaggatttc tgtcagcaca tcgtttgtct gctgtaaaat ctcgtgattc
    24361 caaaaccgca gtacggtaaa gcccaagctg ttgagatatg ccgtccgcgc gtggtcgtat
    24421 acggcttgtt ccgcgtgctg cccgccgtct gcttcgacaa tcagcttggg cgttacgcac
    24481 ataaaatcaa caatataatt ccccatcggc tgctggcggc ggaatttata gccgttcaga
    24541 cggcctgccc gcaggtgctg ccacaatttt gcttccgcct cgctcatttc ttggcgcatg
    24601 gctttggcgc gttggcgcaa gatggggttg tcggtggtca agagtttctc gtgcgggttc
    24661 attttgttgt cgtgctgttt gctgccctct ctctaactct ctcccacggg gagagaggac
    24721 ggggcggttg ttggggttaa aggggctgta aggaaaacaa gtcgttcagg ccacttttta
    24781 cttttcagac gacctgcaat caacggttgt aaatccaagt tgcttttcaa accgcctgta
    24841 accgcaaaac ttgctgcaac ctaccccctc ccccgtgggg gagggctggg gagagggcat
    24901 tctccgaatc gcggcaatct ttccctaatt ccctaactgc ctcaatacaa gcctttcggc
    24961 ttgttgccct ctctctaacg ctttcccacg ggagagagga cggtgcggct gtagtgatta
    25021 agggttttgc aaggaaaaca aggaaaacaa gttgtacagg ctgtttttta tttttcaagc
    25081 gacctgaaat caacgcttgt aaatccaagt cgcttttcaa actgcctgca accgcaaaat
    25141 ctgctgcaac ctaccccctc ccccgtgggg gagggctggg gagagggcat tttccaagtt
    25201 gcggcaatct ttcccaaatc ccttagtctt ctaaaataca agccttacgg ttgttgccaa
    25261 atgaaacttc ttccataccc aaaacttgcg tgtaaaacgc aatggttcgg tcaatgtcgg
    25321 caacggtcag taccagatgg tcgagtgcgc taatcttcat ttcccgcttt ctttttcagg
    25381 cggcggcagt gccgtctgaa agccattatg cccgttttgc cgctttcata ttgccaatga
    25441 atttgtcaaa caaatagccg acatcttgcg gaccggggct ggcttcgggg tggccttgga
    25501 agcagaacac aggtttgtcg gtcagctcga tgccttgcaa agtgttgtca aacaaggatt
    25561 tgtgggtaat gcgtgcgtta gcgggcaggg tgtcggcatc aacggcaaaa ccgtggtttt
    25621 ggctggtgat gacgactttg ccgctgtcca aatcttgcac agggtggttc gcaccgtggt
    25681 ggctgaagcg cattttcagg gttttcgcgc cgatagcgag gctgatgagc tggtgtccca
    25741 agcagatgcc gaaaatcggt ttgccgcttt ccatcagttt ttgcacggct tcgatggcgt
    25801 aggtgcaagg ctcggggtcg ccggggccgt tggacaggaa cacgccgtcg ggattgagtg
    25861 ccaacacgtc ttgtgcgctc gtttgggcgg ggacgacggt caggcggcag ccgcgcgagg
    25921 cgagcatacg caggatgttg gttttcacgc cgaaatcgta ggcgacgacg tggtaaggct
    25981 gttcgtcagg ggtaacgaaa cccttgccca attcccattc gccttccgtc cattcgtaag
    26041 tttccgtgca ggaaacttct tttgccaagt ctttgccgac catactgccg aacgcggcga
    26101 tgagttcttg cgctttttcg attgtggcat ccgcaccggt cagaatcgcg ccgccttgcg
    26161 cgcctttttc gcgcaacagc gtggtcaggc ggcgggtgtc gatgtcggcg atggcgacgg
    26221 tttggttgcg taccaaatag tcgtgcaggc tttcggaggc gcggaagttg ctgtgcaaga
    26281 gcggcaggtc gcggataatc aggccggagg cataaacgct gcggctttct tcatcttcgg
    26341 cgttggtgcc ggtgttgccg atgtgtgggt aggtgagggt aacgatttgt ttgcagtagg
    26401 acgggtcggt caggatttcc tgatagccag tcatcgaagt attgaacacg acttcgccgg
    26461 aagtcgaacc ttcgtaaccg attgatgtgc cgtggaatac gctgccgtca gcgaggacga
    26521 ggagggcggg ggtgctcatg atgggaatcc tgtttttaat aaaattcttg acaatgccgt
    26581 ctgaagggac ttcggcaggg ggcatccggt cggaaaaatc cggtcaaaaa aaaacacgcc
    26641 gcgcaagata gacgcgtaac gtgcttttcg ggcaagtgcc tataccctga aagcagcata
    26701 ttttaagacg aaacataccc gatttcaagc gcaaacgcgg caggcgggct gatatgttcg
    26761 cgcgaaaacg gaaatccgtg gcgtaaaacc gcccgctccg cgcccactat gcccgttacg
    26821 catttcccca cgtccgtccg gcgaaactat gggaataccc gaatcgtcag gaatacctga
    26881 atcgtcagga atacctgaat cgtcaggaat acccgaaccg tcattcccgc gcaggcggga
    26941 atccagacct gtcggcacgg aaacttatcg ggtacaacgg tttcttgaga ttttacgtcc
    27001 tagattcccg cctgcgcggg aatgacgcgt ttcatttgcc gcccctcccg aaaaacgcaa
    27061 aaaatgccgt ccgaaaacct ttcggacggc attttcgcgt gcaaatcagt agaagacttc
    27121 acgccagctg attcgtttca taccgcacgt cgggccggta atgtccaagc tgtccaaatc
    27181 gttcatcagc agggtgcgca cccctttttg ggagaagcag cggttgtttt tgccggaacg
    27241 cttgccgtcg gggtctatac cgctgccgcc cgcatcaccg tctgccgttg ttgaaaatcc
    27301 gtctgttttc ttttcatcca gataacgcac attaaccggt ttgtcgtaaa catatccgtt
    27361 cgggcagacg atttcattgc ctttttgcat acaacctata gggatggatt tgcctttggt
    27421 ggtttgctta tggccggaat attgcgcgac agccgtattg gcttccggca caatcgggcg
    27481 cgcgcttttc ttcgtcagct tgccgccgtc ggcggtattg atgcccaaaa tggcggtttc
    27541 cgcgccgcag ccgccgtcgt tatatttgcg gatggttaca aaggcggtac gcaataccac
    27601 ggtcggtttg acggtaacgc gctgtccggg ctgcaatttc actacccagc ccttgtcgcc
    27661 cgagccgtcg gatcgcttat aatcggtcag gaataaggtt ttattttcct cactaagctt
    27721 ttgctcgagc agccctttgc cctgcccgtc ttgcgccgta cccgtgtctg tgtcattgtc
    27781 aaaaataccg taaatagatt gtatatcatt attatcaaca tcttcctcac tcaaatcact
    27841 gcccgtgccg aagatgacca cgcgtttgtc tttcagttgg gaaatggcgg gcgcggaagt
    27901 aatcggtttg ttgccgctga aaatggtgcg tacagaccat tgttgaggat cttgaccgct
    27961 taaatcaaag cggtacattt tcccgccgcg atcgccggca taggcgatat cgaccgtgcc
    28021 gtccaaatct ttatccacca acgtggggga cgaaagcccg cccttgccgc cgggtacatc
    28081 gattttttta atcagcgtac cgctgctttc caaatcatac acatacagcg cggttttatt
    28141 ttgttggtcg tcaatggttt tagtcgcata accggaggcg aggaaagcgg cgtatttgcc
    28201 gtcgtgggtt ttgccgattt gcggcgtgcc gacggtgtag cctaattgca cgctattatt
    28261 gctattattg ccattattgt catgtttgac atcaaacagg gaaacggcgg tcgggtcact
    28321 gccgtcggct ttggtcaaat ccaaggcgta tgcgcctctg ccgccaaagc ccatcgcgcc
    28381 gaacataaac acatggtctt taccgtttaa gttaacttgg cgcaagacaa agccgccgtc
    28441 cacgccgtag cggtcgccca catagccttt ttcggcaaag gcgcgcagct ctttggcgag
    28501 tgtagaatct ttgctttcaa tatccttgcg cggcatcgtg cccgggatat aactgagctt
    28561 cagactatag ttgcgctcgt ccccgccgtt gccttttttg aagatatgca ccatcccgtc
    28621 gttggcggaa gtagccaaat acccgccgac cgccacgatg gggctgttga cgatgtcgcc
    28681 caaatcgcgc ttgctattgt tgccgttgtc gcggctgcgg tatttttgac tgtattttgg
    28741 cttgccgttt ttttcttctt tgttgaatgt tttaaattga tcgtcattga caccccgaac
    28801 cgtccaaggc agcagcactt ttttccactc gctgtcatca ggcatgaagc tcccttcact
    28861 aacaatgccg aaagtgtcgt tgccgttgtt tcccttaaaa ccttcgacct cattgccttt
    28921 aagtttgatc tgatgtacgc ctttatccaa tcggatgacg gtttgccgcc ctgtgaaagt
    28981 cggctctcga ctttcaatat ccgacttatt caaggttgcg agggaatagc ggccgggttt
    29041 gttggggtcg ttttttcttt tcagattttg aaggaagatg cggctgctcg aactgtcggg
    29101 gtaggtagaa accgaagcgg aatacatctc catcttacca ttttgcacag gtccgaacca
    29161 cagcgcgggg gcagtcagtg cgggggaagg ggctttggta ctcttattgg ggttatttgc
    29221 gttgatgcag cggcctgctt tgacttccgg caggccgagc ttgaccggaa tctgcccgtt
    29281 atctttaatg tcccaactag cccaaaaatt tagcaagccg gcaagccccg tatttctttg
    29341 cagccgcaca tcgatgctcg gcctcaagac acccaactgc actgttttgt cggtgatatc
    29401 tttaatccct tttttgtcca gcaggtgcag tttggcgttc agataataga ccacggcggt
    29461 atgttcgcgc tgctggtcgc caagggaaat agggtcacct tctgtcgtag agacgatggt
    29521 ttgattatta ttgttttcat taaaagaaga tatcaatttg ctggatgatt tgccattttt
    29581 gacggtattc tcgctgccca aattgaaaga cacgcccaac catggatgat ccttcaattt
    29641 gtaaatgggc gaattgtcgc ggcttgggtc tgtgtgccta tccagcctgc ctcctatttt
    29701 ttccaagtcg ggattatcga aggaaaatcg ggttttatag acaagtttgg gacagcctgt
    29761 gctgcttttg catacgacac tggcgtagct gtagcctgcc agcgcgatgc gggtggtacg
    29821 aatccaaccg gcggcattgt tgcgcttttc cagcccgtcg gcatcaaaac cggaaacctt
    29881 gccgtagggc ggcaggtagg tggctgtgcc aaaaacggca gtaccgcttt gtcgagaaac
    29941 aagctcatcg ctattgttga atgagacaga gcctccaccc gatcggcctt tattatagat
    30001 aaatttgcgt tccctgtctt tttcccttaa ggttgaatat gaaccctcct gctttacctc
    30061 cggctgattt tgttcgttca tgacaatagc gtagttatgg gtttgcgcct gcgccccccc
    30121 ccgccggtat gggaaaacat caagatggcg gcataaagcg cggtatggcg gaaaacccgc
    30181 ctttttaaag ttttattcat cgtatttcct tttcggtcaa accccccgcc cttcgggcat
    30241 ccgtccttcg gggcggcagg atcaggcttt gtccgggagg ggtgcagccc cttccgaatc
    30301 agggcggcgc cttatgtgcc gccctgcgtg ttggaacata ttttatccct taaatcttgc
    30361 ttcgcgggat accgtcggcg gcaggcgcgc cgcaaacggc gggattcggc aaaccgcccg
    30421 attccgcgcc cgccgaattg ccggttggaa aacccctttg gcccggctgc caaaggggga
    30481 tgttcggaaa agtaacacgc ccctttggcc ggatgcaatg tatagggtta ccgcattatt
    30541 ctacccttgc gcgctgatca tggtaaagcg gttttcggca atccgcaacc gcctccttgg
    30601 cccgccattg ccgcgaaagc gggaatccgg aacgtaaaat ctcaaaaaaa ccgttttatc
    30661 cggcaagttt gcccgccggc aggcccgcca ttgccgcctg cgcggcaatg gcgggccggg
    30721 gaggcggcat tttccaagtt gcggcaatct ttcccaacaa ctcaaccgcc ccaatacaag
    30781 cctttcggct tgttgccctc tctctagctc tctcccacag ggagagagga cgggtcggct
    30841 gttggggttg aggtttgctg caaggaaaac aggttgtgca ggctgctttt tatttttcag
    30901 acgacctgaa acaacagctg taaatctaag ttgcctttca aatcgcctgc aaccgaaaaa
    30961 tctgccgaaa cccactccct cccccgtggg ggagggccgg ggaggcggca ttttccaagt
    31021 tgcggcaacc tttcccaaca actcaaccgc cccaatacaa gcctttcggc ttgttgccct
    31081 ctctccagcc ctctcccacg gggagagagg acggggaggc tgttggggtt aagggttttg
    31141 taaactaatc aggttgtgca ggctgctttt tgcttttcag acgacctgca tcaacggttg
    31201 taaatccaat ctgtttttca aaccgcctgc aaccgcaaaa cctgccgcaa tccgctccct
    31261 cccctgtggg ggagggccgg ggagagggca ttctccaagt tgcggcaatc tttcccaaca
    31321 gcttaaccgc cccaatacaa gccttgcggc ttgttgccct ctctccagcc ctctcccacg
    31381 gggagagagg actatgaagc ccgccggcag gcgcggggct tgggacggca ttgctgttgc
    31441 ggtttcggac gcggctttat tcgacgacaa ttttagggaa ccggctgctg aagtctttgc
    31501 ctttgtcggc aatgcccagg gcgatttgga atgcggcatc ggtgtagatt cgggcgatgg
    31561 cggggtgttc gtcgaacagt tgcgccggtg tgccgccgtc cattgcttcg cgcacgggca
    31621 ggcttagggg aagctgtccg agcaggggga cgttgaggcg tgcggctaaa tctttgccgc
    31681 cgtccgtgcc gaacagggct tcgctgtgtc cgcagttggt gcagatgtgg acggacatat
    31741 tttccaatac gcctaaaatg ggaatgttga ccttgcggaa catatccaca gccttgcgcg
    31801 cgtctatcag cgcgatgtcc tgcggcgtgg ttacgatgac ggacccggta acggggatgc
    31861 gttgggacag cgtgagctgg atgtcgccgg taccgggggg caggtcgatg aaaagataat
    31921 ccacttcgtc ccactcgctt tgaaacatca gttgctgcaa ggcttggctg accatcggcc
    31981 cgcgccagac gacggcttgg tcggtatcga cgagaaagcc gatagacatg acctgtatgc
    32041 cgtctgaaga ttcgacggga atgagttttt ggtttttctg atcgggtttg cggtcgtcca
    32101 cacccagcat cgtgggctgg ctcgggccgt aaaggtcggc atcgagtacg ccgacgcgcg
    32161 cgcccatgcg cgccattgcg gcggcaaggt tggcggtggt ggttgatttg cccacgccgc
    32221 ctttgccaga ggcgacggcg atgatgtttt tcacgccttt aatagtggta acgccgggct
    32281 ggactttgtg tgtgccgatt tcagtgtcca tggacagatg gatgtgtgtg tcgcctgtca
    32341 gcggcatcag gatttcctgt atgcggtcgg ctgtttctga ggcaatgtgc gcgacgggga
    32401 agccgaaatg cagggcgata tggatgccgt ctgaacgctg ttcgaccgaa cggacggcct
    32461 tttcgccgcc gagcgtgcgt gccgtattcg gaacggcgac ggtgtcgagg agggtgcgga
    32521 tgttttgtat gttcataatg tgtgtttctg tgtgcagttt gggaaacggg cggaaagtgt
    32581 acattgattt cgggcggttt gcttttcctt gtgcgaactt ttacacggta tgcggcggat
    32641 tgtgaaaatc cgttgtcaaa atatcccgtg caaacagtgg tctgcaatta agcctgtaaa
    32701 atttgcttga cgaggtagga tggtgctgta taatgcacgg cttatcgggt cgttagctca
    32761 gccggtagag cagcggactt ttaatccgtt ggtcgagcgt tcgaatcgct cacgacccac
    32821 cagataaccg gaagccaagt tttgagactt ggctttttgt ttgcctgccg gttgcgcggg
    32881 cgtaccgttt gagagagcgt atgaaaaaga aactgctttc gggcatcaaa tttgccgttc
    32941 agacggcatt ggtgttttta ttggtgtcgc tgtttttgga ttggatacgc aagcccgaag
    33001 agccggccgg tgcggcaggg cggcctttga ccctgctgtc ggggcagcgg ctgactttgg
    33061 gacagtttag ccgggataag gcgattttgg tgtatttttg gggaagctgg tgcggcgtgt
    33121 gccgttatca gtcgccgata atcgatgatt tggcggcgga cggcgttccg gtcgtcggcg
    33181 tggcggtacg ttccggcagc gcgtccgaag tggcggcgta tatggcaaag cggggcttgg
    33241 gctttccgac ggtcaacgat gaggacgggg gtttggcaag gtcttggcgg attgtcgcaa
    33301 cgcctgccgt cgttttggtc aaaaatggga aaatggttca ctatacgacg ggaatcagca
    33361 gttattgggg cttgcgcgca cgaatttttc aggcggatgt tttcggttaa cttttgtttt
    33421 tgttaaactt tacgctatgt agagaatcaa acggcatata ccttgctcgt ctgatgcggc
    33481 ggcttttgtt ttttctggaa gaaagttctt tcgacagtaa atgtaatact ttgttgagat
    33541 tgtagggaaa atagactaag atataactat taaaatattt ttagatagga ttatcggaat
    33601 taaagtcttt tatacccagt cgtccgatgc ggtttatagc gtattgttgc tatatgttcg
    33661 ttttgttata taacggttgc atcaaaaatt acgcccacag gctttcccga cggtttgaaa
    33721 gtttgatttt cgataacttg gagacttgaa caatgcctaa ccaatcaaaa catgcgtcta
    33781 tcaatatcag tctgatacag gcaagggaag ccctgatgac ccaattcagg cctattctga
    33841 atcaggcgaa tattaccgat cagcaatggc ggattatccg tcttttggcg gaaaacggca
    33901 cgctggactt tcaagatttg gcgaatcagg cgtgcatttt gcgccccagc ctgaccggta
    33961 tcctgacccg ccttgaaaaa gcgggtttgg ttgtccgcct gaaaccttcc aacgaccaac
    34021 gacgtgtttt tctgaagctg actgccgagg gcgagaagct gtatgaggaa atcggcgaag
    34081 aagtggacga gcgttacgac gctatcgagg aagtgctggg ccgcgagaaa atgctgctgc
    34141 ttaaagacct gttggcagaa cttgccaaaa tcgaggatgc gttgaactcg taatacgccg
    34201 taacgcgcgg aaatgtccga ccgacggctt tttgaatcag aactgctgca catggggggt
    34261 gccttgtgtg cagcattctt atatagggga cagtttaaag gggaaaaatg gcggatttgc
    34321 agaaaacttt tcaaacttcg ttccgtgatg cgatggcatc ttgcgcggca ggcgttcatg
    34381 tcatcacgac agacggtgcg gcagggcgtt acggcattac aatgacggcg gtcgcgccgg
    34441 ttaccgacga gccgccgacc gtgatgctgt gcatcaaccg gagtgcgcga atcattccga
    34501 tcctgtcgga aaacggcagc ctgtgcatca atacgttggc agacgaacat caggatgtgg
    34561 ccgaacattt tgccggattg accaatcttt cacccgaaga acgttttgcc tatcatattt
    34621 ggcattacgg taaaaccgga caacctgaaa tagaaggcgc gttggcgcat ctgcacgggc
    34681 atattgtcgg ccaacatgaa atcggcacac attttgtgtt ttacgtcagg ctcgacgaaa
    34741 ttaaaaattg cgtgggcaaa cgtcccgcgc tgctttattt cagacggcag tttagatctt
    34801 tagactgata ttcggacaga tatatatgaa agcgatgata ctggcggcag gacgcggcga
    34861 gcgtatgcgc cctttgaccg ataccactcc gaagccgctg ctcgatgtgg cgggtaagcc
    34921 tctaatcggt tggcacctat gccgtctgaa gcaggcaggg tttaccgaaa tcgtcatcaa
    34981 ccacgcttgg ctgggtcggc agatagaaga ggctttgggc gacggctcgg cttatggcgt
    35041 gaacatcgcc tattcgcccg aacctgaagg cggcttggaa accgcaggcg gtatcgcacg
    35101 ggcattgccg ctgttgggcg atgccccgtt tttggtggtc aacggcgacg tgttgaccga
    35161 catcgatttt accgccgcgt ttcaggcggc atcgtccctg cccgagcaca tttccgccca
    35221 tctgtggctg gtggaaaatc ccccgcacca tcctgacggc gatttttccc tgctgcccga
    35281 cggcagcgtg cggccggaag taaatggcgg caacggattg acatttagcg gcgtgggtat
    35341 ttaccgtcct gaaatgtttg acggaatcga agcgggcagt gtggcgaaac tcgcgcccgt
    35401 attgcggaac gaaatgcggc aaaaccgcgt gagcggtcag aagcatacgg gcttgtggct
    35461 ggatgtcggc acggtatgcc gtctgaaaga ggctcaagcc cttgcagggg cttggaagtg
    35521 aaataaaacg gtggcttgcc gagccggctg ccgaacggtt ccgaccggat gtccggcata
    35581 ttttcgtgga ggcgtgaaaa tagggcgttc ggggctttcc gtccaacaaa tgccatctga
    35641 agcgcggcgg tttgccgtcg gcgcggtgtc ggattttatt gggtaacttt gttcagaccg
    35701 ccgcccgtca gattgtcaaa acccggtttc aggcggtatg gcggattcgg tttaacgttt
    35761 caacgccagc accaacacgc ccgccgttac cagccccaag cctatccatt cctgcgtgtt
    35821 cgggcgttcg tccaagaaaa ccaccgccat cagcgcgacc agaaccaggc tgaatttatc
    35881 gacgggggcg acttgcgagg cgttacccag ttgcagggct ttgaagtagg caagccaaga
    35941 tgcgccggta gcaaggccgg ataggataag gaatgtccag ttgtgccccg taaagccgtt
    36001 cacgccctgc catttgccgg tgtaggtcaa aaacagtacc aaagcggcga ggatgaccaa
    36061 ggtgcggatg aaggtagcga aatctgaatc tataccctgc aagcccattt tggcgaaaac
    36121 ggcggtcaat gaggcgaagc ctgccgatgc caatgcccaa aacagccatg cgttgctgcc
    36181 catgttttct ccttggattg tgaacaatat gaacggtatt tttgttgcag cgtcaaaaat
    36241 ttcactgcgg gtttggtgcg gataacgtta taatatgcct gatattattt tcaatccacc
    36301 tgtttgtcgc ctgatgcttt cagacggtat gtccctcctc atttctaaag gaaaatcatg
    36361 agcttcaaaa ccgatgccga aatcgcccag tcttccacca tgcgcccgat tggcgaaatt
    36421 gccgccaagc tgggcctgaa cgccgacaac attgagcctt acggtcatta caaagccaaa
    36481 atcaatcctg ccgaagcgtt taaactgccg caaaaacaag gcaggctgat tttggtaacc
    36541 gccatcaacc cgactcctgc cggcgaaggc aaaaccaccg taaccatcgg tttggcggac
    36601 gcgttgcgcc acatcggcaa agatgccgtg attgccctgc gcgaaccttc tttagggccg
    36661 gtgttcggcg tgaaaggcgg cgcggcaggc ggcggctatg cccaagtttt gccgatggaa
    36721 gacatcaacc tgcacttcac cggagatttt cacgccatcg gtgcggcaaa taatctgctt
    36781 gccgcgatgc tcgacaacca tatctaccaa ggcaacgagt tgaacatcga ccccaaacgc
    36841 gtgctgtggc ggcgcgtggt cgatatgaac gaccgccagt tgcgcaacat catcgacggc
    36901 atgggcaagc ctgttgacgg cgtgatgcgt cctgacggtt tcgatattac cgttgcttcc
    36961 gaagtgatgg cggtattctg tcttgccaaa gacatcagcg atttgaaaga gcgtttgggc
    37021 aacatccttg tcgcctacgc caaagacggc agccccgttt acgccaaaga tttgaaagcg
    37081 aatggcgcga tggcggcatt gcttaaagat gcgattaagc ccaacttggt gcaaaccatc
    37141 gaaggcacgc ccgccttcgt acacggcggc ccgttcgcca acatcgccca cggctgcaac
    37201 tccgtaaccg caacccgtct ggcgaaacac cttgccgatt acgccgtaac cgaagcaggc
    37261 ttcggcgcgg acttgggcgc ggaaaaattc tgcgacatca aatgccgcct tgccggtttg
    37321 aaacctgatg cggctgttgt cgtggcgact gtccgcgcgt tgaaatataa cggcggcgtg
    37381 gaacgcgcca acctcggcga agaaaattta gacgctttgg aaaaaggttt gcccaacctg
    37441 ctgaaacaca tttccaacct gaaaaacgta ttcggactgc ccgtcgtcgt tgcgctcaac
    37501 cgcttcgtgt ccgactccga tgccgagttg gcgatgattg aaaaagcctg tgccgaacac
    37561 ggcgttgaag tttccctgac cgaagtgtgg ggcaaaggtg gtgcgggcgg cgcggatttg
    37621 gcgcgcaaag tcgtcaacgc cattgaaagt caaaccaata acttcggttt cgcctacgat
    37681 gtcgagttgg gcatcaaaga caaaatccgt gcgattgccc aaaaagtgta cggcgcggaa
    37741 gatgttgatt tcagcgcgga agcgtctgcc gaaatcgctt cactggaaaa actgggcttg
    37801 gacaaaatgc cgatctgcat ggcgaaaacc caatactctt tgagtgacaa cgccaaactg
    37861 ttgggctgcc ccgaaggctt ccgcatcgcc gtgcgcggca tcaccgtttc cgccggcgcg
    37921 ggcttcatcg tcgcgctgtg cggcaatatg atgaagatgc cgggtctgcc gaaagttccg
    37981 gccgccgaga aaatcgatgt ggacgaacac ggcgtgattc acggcttgtt ctgaacggtt
    38041 tttgaaaccg gatgctgtct gaagccgttt cagacggcat ttttcggaac gcgggcggcg
    38101 gtatgctata atccgccgtt aaatttctct attttcagga aaaaacatga gtttgaaatg
    38161 cggcatcgtc ggtttgccca acgtcggcaa atccaccctt tttaacgcgc tgacccaatc
    38221 gggtatcgaa gcggcaaact atcctttctg taccatcgaa cccaacgtcg gcatcgtcga
    38281 agtccccgat ccgcgtatgg ccgaattggc aaaaatcgtc aatccgcaaa aaatgcagcc
    38341 tgccatcgtc gaatttgtcg atattgccgg tttggttgca ggcgcgagca aaggcgaggg
    38401 cttgggcaac cagttccttg ccaacatccg cgaaaccgat gcgattgtga atgtcgtgcg
    38461 ctgctttgac gacgacaaca tcgtccacgt ttccggcaaa gtcgatccga ttgccgacat
    38521 cgaaaccatc ggtacagagt tggcgcttgc cgacttggca agtgtggaaa aagccatcgt
    38581 ccgcgaagaa aaacgcgccc gttccggtga caaagacgcg caaaagctgg tcgatttgtg
    38641 caaaaaactg ctgccgcatc tggacgaagg caaacccgtg cgttccttcg gtttggacgc
    38701 ggaagaacgc gcgatgctca aaccgctgtt cctgctgacc gccaaacctg ccatgtacgt
    38761 cggcaacgtt tccgaagacg gttttgaaaa caacccgcac ctcgaccgcc tgaaagaatt
    38821 ggcggcaaaa gaaaacgccc ccgtcgtcgc cgtgtgcgcc gcgatggaga gcgaaatcgc
    38881 cgagttggaa gacggtgaaa aagccgagtt cctcgccgaa atgggcttgg aagaaccggg
    38941 cctgaaccgc ctgatccgcg ccggttacga ccttttgggg ctgcaaacct acttcactgc
    39001 cggcgtcaaa gaagtccgcg cgtggacgat acacaaaggc gacacagccc cacaagccgc
    39061 cggcgtgatt cacaccgact tcgaacgcgg cttcatccgc gcccaagtca tttcttacga
    39121 cgactttgtc tcgctcggcg gcgaagccaa agccaaagaa gccggcaaaa tgcgtgtgga
    39181 aggcaaagaa tacgtcgtgc aggatgggga tgtgatgcac tttttgttta acgtgtaacc
    39241 caaatgcggc aggttttcag acggctttgc cagaaatgcc gtctgaagcc ggttttggtg
    39301 gttttcggcg tttccatacc gccggaatgc ggctgcatca aaataaaatc ccacccgcat
    39361 ttccgatttg ccctccccga ttcctgcaaa acaaaccgcc tgccccgctg ttgcaaaaag
    39421 ccgtccggca ttccgaatat cccgtacaaa atgacctttc agacggcatt tgcgccgccg
    39481 cgtttcgagt atagtggatt aactttaaat caggacaagg cgacgaaacc gcagacagta
    39541 cagatagtac ggcaaggcga ggcaacgccg tactggttta aatttaatcc actataaaaa
    39601 cattatgagc caagccttac cctaccgccc ggacatcgac acattgcgcg ccgccgccgt
    39661 cttgtccgtc atcgtgttcc atatcgaaaa aaattggctg ccgggcgggt ttctcggtgt
    39721 cgatatattc ttcgtgattt caggcttttt gatgacgatg attcttcacc gcgaaatgtc
    39781 gggggggggg gggaggtttt ccctgaaggc attttatatc cgccgcatca agcggattct
    39841 gcccgcattt ttcgccgtat tggcggcaac gctgacaggc ggcttctttt tattcaccaa
    39901 agatgatttc tttcttttat ggaaatccgc gctgaccgcc ttgggtttcg cctccaacct
    39961 gtattttgca agggggaagg attatttcga tcccgcgcag gaagaaaagc ccttgctgca
    40021 catttggtct ttgtcggtcg aagaacaatt ttactttgtc tttccgatat tgctgctgct
    40081 tgtcgcccgc aaaagcccgc gcgtacagtt cggcttcctc gccgcattgt gcgccttaag
    40141 ccttgccgct tcctttatgc cttccgcgtt cgataaatat tacctgcccc acctgcgcgc
    40201 ctgcgaaatg ctggtcggat cgctgaccgc cgtgtggatg cggtaccggc aacagcggaa
    40261 tctcgccgtt ggcagatgct gtgccgccgc cggcgcattg ttttccgcgt gcatactgtc
    40321 cgcctgcctg tttgcctatt cgaaacaaac cgcctatttc ccgggacccg ccgctttgat
    40381 tccctgtctg gctgttgccg cgctgattta tttcaatcat tacgaacacc cgcttaaaaa
    40441 atttttccaa tggaaaatca ctgttgccgc cggtttgatt tcctattcgc tttatctgtg
    40501 gcattggccg atattggcct ttatgcgcta tatcggcccg gacaacctgc cgccttattc
    40561 aacagcggca gcaatcgtcc tgatattgct gctttccctg atttcttatc actgcatcga
    40621 aaagccgttt aaaaaatgga aaggttcgtt cgcacaatcc gttttatgga tttatgcctt
    40681 gcctatgctc attttggggg cgggctcgtt tttcgcgatg aggctgccgt ttatggcgca
    40741 atacgaccgc ttggggctga cgcgttccaa cacctcctgc cacaacaata ccggcaaaca
    40801 atgcctgtgg ggggatacgg aaaaacagcc ggagctgctg gttttgggcg actcccacgc
    40861 cgaccattac aaaacattct tcgatgccgt gggcaaaaaa gaaaaatggt ccgccactat
    40921 ggtttccgcc gacgcttgcg cctatgtgga aggctacgcg tcccgtgtgt tccaaaactg
    40981 ggccgcctgc cgcgccgttt accgctatgc cgaagaacac ctgcccctgt attcaaaagt
    41041 ggttttggcg atgcgctggg gcagccaaat gcccgaaaac agccgctccc ttgcctacga
    41101 tgccggtttt ttccaaaaat tcgaccgtat gctgcacaaa ctctcatccg aaaaacaagc
    41161 cgtttacctg atggcggaca accttgcctc gtcttacaac gtacaacgcg cctatatctt
    41221 gtcttcacgc ataccgggtt accgccaaac cctgcgcccg gacgacgaaa gcactctgaa
    41281 agccaatgca cgcatcaggg aattggcagc caaatacccc aacgtctata ttattgatgc
    41341 cgccgcctat atccccgcaa atttccaaat cggcggattg ccggtttact cggacaaaga
    41401 ccacatcaac ccttacggcg gcacggaatt ggcgaagcgt ttttccgaaa aacaacggtt
    41461 tctcgatacg cgccataacc attgattcgc ttaaatttgt tacaatcggc ggtttgcaaa
    41521 accgctaatt ttttttgaaa gagaccgatg agcgtcatcc aagacctgca atcgcgcggc
    41581 ctaatcgcgc aaaccaccga catcgaagcc ttagacgctt tgttgaacga acaaaaaatt
    41641 tccctttatt gcggcttcga cccgaccgcc gacagcctgc acatcggaca cctgctgccc
    41701 gtattggcat tgcgccgctt ccaacaggcg gggcatacgc cgattgcact ggtgggcggt
    41761 gcgaccggta tgatcggcga ccccagcttc aaagccgccg aacgcagctt gaattccgcc
    41821 gaaaccgttg ccggctgggt ggaaagcatc cgcagccaat taaccccttt cttgagcttt
    41881 gaaggcggaa acgccgccat tatggcgaac aacgccgact ggttcggcaa aatgaactgc
    41941 ctcgacttcc tgcgcgacat cggcaagcat ttctccgtca acgccatgct gaacaaagaa
    42001 tccgtcaaac agcgcatcga ccgcgacggc gcaggcattt ccttcaccga gttcgcctat
    42061 tccctgctgc aaggttacga cttcgccgag ttgaacaaac gccacggcgc ggttttggaa
    42121 atcggcggct ccgaccaatg gggtaacatc actgccggta tcgacctgac ccgccgcctg
    42181 taccaaaaac aagtgttcgg actgactctg cctttggtta ccaaatcaga cggcaccaaa
    42241 ttcggcaaaa ccgaaggcgg cgcggtgtgg ctgaacgcga aaaaaacctc gccctatcag
    42301 ttctaccaat tctggctgaa agtcgccgat gccgatgtgt ataaattcct gaaatacttt
    42361 accttcctgt ccatcgaaga aatcgacgct atcgaagcga aagataaagc cagcggcagc
    42421 aagcccgaag cgcaacgcat cctcgccgaa gaaatgaccc gcctgattca cggcgaagaa
    42481 gcccttgccg ccgcgcagcg catttccgaa agcctgtttg ccgaagacca aagcagcctg
    42541 accgaaagcg acttcgagca gctcgccctc gacggcctgc ctgcatttga agtttcagac
    42601 ggcatcaatg tcgtcgaagc cttggtcaaa accggtttgg catcctccaa taaagaagcg
    42661 cgcggctttg tgaacagcaa agcggttttg ctcaacggca aacctgccga agccaacaac
    42721 cccaaccacg ccgccgaacg ccccgacgat gcctgcctgc tgaacggcga acacaaacgt
    42781 ttcggcaaat acaccatcct tcggcgcggc aaacgcaacc acgcgctttt ggtttggaaa
    42841 taatccgatt gccgcagaaa tgccgtcatt cccgcgcagg cgggaatccg gacctgtccg
    42901 cacggaaact tatcgggcaa aacggtttct tagattccac gttctagatt cccgcctgag
    42961 cgggaatgac gagtttcaag attacggtgt tgtcggaacg caactgaacc gtcattccca
    43021 cgaaagtggg aatctagaat ctcggggttt gagcaactgt ttttatccga taagtttctg
    43081 tgcggacagg tccggattcc cgcctgcgcg ggaatgacgg cggagggttg cttgtctcgg
    43141 tttacctggt taaaaaagaa cgattttcac tgatgttgca tcaggtttgg ggcgatgttt
    43201 caacacatag caccgcgcct gctgcgcgct ttatgcgttt ggcgcgttcg gctgcgggaa
    43261 atttgcctac ttttcccgcg tcgggcgggc gtaacgggcg gcacactgtc tataaaccgc
    43321 aataccgttt acaatgaccg cctgtttcac cacatacccg aacataacaa tgagaatcag
    43381 gctggggcgg cacaacgcgc ccgactttcc gcacggggcc gccgtaacca taggcaattt
    43441 tgacggcgta cacctcggac acaaacacat cctccaaaaa ctccgcctcg aagccgatac
    43501 gcgcggatta cccgtcgtga ccgtcgtttt cgaaccccaa cccaaagaat ttttcgcact
    43561 ccgcaccggc aggatgccac cgtgtcggat cagccccctg cgcaccaagc tcgaattatt
    43621 ggaaggcaca ggctgtgtcg atgccgtctg ggttttgcgt ttcgatcaaa atttttccga
    43681 aatatccgcg caagggttta tcgaccgcct gctgcgtcaa accttgaata cgcgttattt
    43741 gctcgtcggc gacgatttcc gtttcggtgc ggggcgggaa ggctgttttg aacttttggc
    43801 acaacagccc gatatgcaga ccgagcgtac gccttccgtc atcgtcgaag acatccgcac
    43861 cagcagtacc gccgtgcgac aagccctttc agacggcaac cttgcctatg cgaaaaaact
    43921 tttgggacac gactacgtct tgagcggcag ggtggtgcac ggcagaaaac tcggacgcac
    43981 cttaaacgcc ccgactgcca acatccgcct gccccgccac cgttatgcac tcggcggcgt
    44041 gttcgtcgtc gaagcggacg gcgcgttcgg cacgcggcgc ggcgtggcga gcttcggttt
    44101 caatcccacc gttgatagcg gctgttctca aaagcttgaa gtccacctgt tcgactttca
    44161 aggcgacctg tacggacaac ggctgaacgt ccgcttcctg cacaaactgc gcgatgaaga
    44221 aaagtttgac ggtatggcag aactgaaaag gcagatagca gccgatatgg aagccgcaaa
    44281 gtgttggtag aaaaacctta tacaaaccat ccgattgggc tacaatcaat cttttaactg
    44341 ttcagacggc ataggggttt cccgttgtga aatactgttt gaggcgcaat gccgtctgaa
    44401 ccgaaatatt gtaacaatag agattaaaaa atgaccgatt acagcaaaac cgtcaacctg
    44461 ctcgaaagcc cgttcccgat gcgcggcaat cttgccaagc gcgagcctgc atggctgaaa
    44521 agctggtacg agcaaaaacg ctaccaaaaa ctgcgcgaaa tcgccaaagg ccgtccgaaa
    44581 ttcatcctgc acgacggccc gccgtatgcc aacggcgaca tccacatcgg tcatgccgtc
    44641 aataaaattc tcaaagacat cattatccgc agcaaaaccc aagccggttt tgacgcgcct
    44701 tatgtgccgg gttgggactg ccacggcctg cccatcgaag tgatggtaga aaaactgcac
    44761 ggcaaagaca tgcccaaagc gcgtttccgc gaattgtgcc gcgaatatgc cgccgaacaa
    44821 gttgcccgcc agaaaaaaga ctttatccgc ttgggcgtgt tgggcgattg ggaccgtcct
    44881 tacctgacca tggatttcaa aaccgaagcc gataccgtgc gtatgctcgg cgaaatctac
    44941 aaatccggct atctctaccg gggtgcgaaa ccggttcaat tctgcttgga ctgcggttct
    45001 tcgctggccg aagcggaagt ggaatataaa gacaaaatct cgcccgcgat tgacgttgcc
    45061 tatccgttta aagacaccgc cgcgcttgcc gccgcattcg gtttggcagg tatcgaaggc
    45121 aaagcgtttg ccgttatttg gacaaccacg ccttggactt tgcctgcgag ccaagctgtt
    45181 tcagcgggtg cagacgtggt gtatcaatta atcgatacgc ccaaaggcaa attggtattg
    45241 gccaaagatt tggcggaaga cgctttgaaa cgctacggct tttcagacgg catttctatt
    45301 cttgccgaaa ccaccggcga caagctggaa aacctgcaca tgaaccatcc gttcctcgaa
    45361 cgcgatattc ccatgcttaa cggcgaacac gttaccaccg atgccggtac cggcttggtg
    45421 catactgcgc ccgcgcacgg tttggaagac tacgccgtct gcaacaaata cggcatcgag
    45481 ctttacaatc ctgtcaacgc cgaaggcaaa tacatcggcg aaacgctgcg cgttgccggt
    45541 atgcgcgttt gggaggcgaa ccccgtcatc ctgcaatggt tggaagaaac cggcaacctt
    45601 ttggcaagca gtaaaatcga acacagctac gcccactgct ggcggcacaa aacgccgctg
    45661 atttaccgcg cgaccggtca atggtttgtc ggtatggaca aagccggtgc cgacggcaaa
    45721 accctgcgcg acaaagccat caaggccgtg gacgacaccg aattcttccc gtcttggggt
    45781 cgcgcgcgtt tggaagccat gattgaaggt cgtcctgact gggtggtttc acgccaacgc
    45841 tattggggca cgccgatgac tttctttgtt cacaaagaaa cgggcgagct gcatccgaac
    45901 tctgccgaac ttttggaaaa agttgccctg aaaatcgaag aaaaaggcat cgaggcttgg
    45961 ttctccctcg ataaaagcga attattaagc gcggaagatt gcgaacatta cgacaaactc
    46021 cccgatacga tggacgtatg gttcgattcc ggttcgaccc attattccgt tgtgaaacaa
    46081 cgcgaagaat tggaatggcc ggcggatttg tatctcgaag gcagcgacca gcaccggggc
    46141 tggtttcaat cgtccatgct gaccggctgc gcctcatcaa tgggacgcgc accgtataaa
    46201 cagctgctga cccacggttt tgttgtagac ggcgaaggca aaaaaatgtc gaaatccatc
    46261 ggcaacgtcg tcgcgccgca agaagtctat aacgaattcg gcgcggacat cctgcgtctg
    46321 tgggcggcat ctaccgatta cagcggcgaa ttggcgattt ctaaagaaat ccttaagcgc
    46381 gtaaccgaaa gctaccgccg tatccgcaat accttgagct ttttgtttgc caacttgagc
    46441 gactttaatc cgattgaaga tgccgtgcaa caggcggata tggtggaaat cgaccgctat
    46501 gccctggtgt tggcgcgtcg gctgcaagag cgtctggcag gcgattacta tccgcgctac
    46561 gccttccact tcgccgtaaa agacattgtt tctttctgct cggaagactt gggcgcgttc
    46621 tacctcgaca tcctgaaaga ccgcctctat accaccaaag cagacagcca tgcacgccgc
    46681 agcgcacaaa ctgccctgta tcacatcaca cgcagtttgg ttctcttgat tgcaccgatt
    46741 ttgtgcttca ccggcgagga agcgtgggac atcatcggcg gcggcgaaga agacagcgtc
    46801 cttttccata cttggcacga gttcccgacc atcaacgaaa aagccgaagc cgaactggtg
    46861 aaaaaatgga cggcaatccg cgaagcccgc gaagcggtaa ccgccgccat tgagcctttg
    46921 cgcgccgaca aaaccgttgg ttcgtccttg caggcggaag ccgaaatcac tgcgccggaa
    46981 gaaatggcca gctacctgaa cgctttgggc gaagaattgc gctttgccct gctggtgtct
    47041 aaagccgaag tgaaagtagg tgatgaactt gccgttgccg ccaaagccag cgatggtgaa
    47101 aaatgcgaac gctgttggca ctacacccac gatgtgggcg cagttgcagg ccatgaaacc
    47161 atctgcaaac gctgcgccgg gaatgtcggc ggagaaggcg aaacgcgcca ttacgcctga
    47221 taaagtttga gcaaatgccg tctgaaaccg ccaaacagca tttcagacgg cattttttgt
    47281 accgcgattt gtctttataa cggcggaggg gtttcaagat tgcggtgttg tcggaatgca
    47341 actgaaccgt cattcccacg aaagtgggaa tctagaatct cgaggtttca gtcatttccg
    47401 atagattccc gcctgtgcgg gaatgacgga tttcaagatt acggtgttgt cggaatgcaa
    47461 ctgaaccgcc attcccacga aagtgggaat ctagaatctc gaggtttcag tcatttccga
    47521 tagattcccg ccgcgtcgtg ggtctggatt cccgcctgtg cgggaatgac ggatttcgag
    47581 attgcggtgt tgtcggaacg caactgaacc gtcattccca cgaaagtggg aatctagaat
    47641 ctcggggttt cagtcatttc cgatagattc ccgccgcgtc aggggtctgg attcccgcct
    47701 gtgcgggaat gacggatttc gagattacgg tgttgtcgga acgcaactga accgtcattc
    47761 ccacgaaagt gggaatctag aatctcgggg tttcagtcat ttccgataga ttcccgccgc
    47821 gtcggaggtc tggattcccg cctgcgcggg aatgacggat ttcgagattg cggtgttgtt
    47881 ggaacgcaac tgaaccgtca ttcccacgaa agtgggaatc tagaacgcgg ggtttgagca
    47941 actgttttta tccgataagt ttctgtgcgg acaggtctag attcccgcct gcgcgggaat
    48001 gacgggtttc aagattacgg catttgccgt ttcgggtaca ggcagggggt tttcgggtaa
    48061 aatagcactc ttttatccga ctgttgaaaa atatgtcttc atctgtttca agtaaaacgc
    48121 gctattgggt attggcactt gccgccatcg tgctggacca gtggtcgaag tgggcggtgc
    48181 tgtcgtcgtt tcagtatcgg gaacgcgtca atgtcattcc ttcctttttc gatttgacgc
    48241 tggtgtacaa cccgggtgcg gcgttcagct tccttgccga tcagggcggc tggcaaaaat
    48301 actttttttt ggtgctggcg gtgacggtga gcgcgtattt ggtacgcgcc atcttgcgcg
    48361 atgagtttgc aaccctcggc aaaacgggtg cggcaatgat tatcggcggt gcgttaggca
    48421 atgtcatcga ccgcctgata cacggtcatg tcgtcgattt cttattgttt tattggcaaa
    48481 attggtttta tcccgccttt aatattgccg acagctttat ctgcgtcggt gcggtgttgg
    48541 cagtgttgga caacatcgtc caccgtaaaa cccaagaaga aaaatattga tgccgtctga
    48601 aaacgaaata ccgggcttat gaacgagaaa accatcatcc ttgccaatcc gcgcggcttc
    48661 tgcgctggtg tggatcgggc aatcagtatt gtcgaacgtg ctttggaaga attcggcgcg
    48721 ccgatttatg tgcgccacga agtcgtccac aacaaattcg tcgtcgataa cctgcgtgaa
    48781 aaaggcgcgg tgtttatcga agacttggcg gaagtgccgc cgggcgcgac gctggtttat
    48841 tcggcacacg gcgtatcgaa ggcggtgcag caagaagcgg cggaacgtgg tttccgggta
    48901 tttgatgcga cttgcccgct ggtgacgaaa gtgcataagg aagtcgcccg actggatgcc
    48961 caagactgtg aaatcatcat gatcgggcat aagggtcatg tcgaggtcga aggaacgatg
    49021 gggcagcttg cgccgggcaa aatgcttttg gtcgaaacgg taggagatgt ggcaaaactc
    49081 gaagtcagaa accccgacaa actcgcctat gtcagccaaa ccacgctctc ggtcgatgaa
    49141 accaaagaca tcatcgccgc gctgaacgcg cgtttcccca atatccgcaa tccgcacaag
    49201 gaagacatct gctatgcgac gaccaaccgg caaaccgccg tcaaagagtt ggcagaacag
    49261 tgcgacatcg tgattgtggt cggttcgccc aattcgtcta acagcaaccg cttgcgcgaa
    49321 gtggcggcat cgcgcggaat cgatgcgtat atggtggata atgcaggcta cctgcaacgc
    49381 gcatggtttg agggcaaaaa caaagtcggc gtaacggcag gcgcgtccgc gcccgaagtg
    49441 ttggtgcagg aagtattggc aaccatacgc gggtgggggc atgaaaccgt gcgcgaaggc
    49501 gagggtgcgg aagaaagcat cgtgttcgtc ctgcccaaag agttgcgccg cgagggcgaa
    49561 accaaacccg atttgtgcaa gcgttgagca agcgttgaat gtttgggcaa aacaaatgcc
    49621 gtctgaacag gcttcagacg gcatttttgc cgcgtgccgg atgcggaaac caatcaggcg
    49681 taatgctgtg caagaaaacc gggcagttcg gacaagtcgt ccaatacggc gagatgcggt
    49741 gcgccaagga gctgttcgcg cgaatgtgcg ccggtggcaa cgccgactgc cgccgcaccc
    49801 gcgttcgccg ccatatgcag gtcgtgcgcc gtatcgccga cgaccaatgc ctctttcggg
    49861 tcaagtccca gtttgccgca gattccgaat accatttcgg gcgagggttt ggagggatat
    49921 tcccccgcgc aggcggtggc gagccaatag ccgccggtgg cggtttggct gatggcgttg
    49981 tccaaacccg cccgcccttt gcccgtggcg acggcaagcc agtatccttg tgctttgagc
    50041 ttgtccagac agggcagtgc ctgaggaaat aaggacatat tgcggttgtt gggattgagg
    50101 taatgtgcgg aataagtgcg tgtgatgtcg gcaatggcgg tttcagacgg catttcgagc
    50161 aggtcgcgga tgatttcggg caggctgaga cctttgcaaa attcctttcc ctcccgacag
    50221 ccgaaacccc aacacaggtt ttcggctgtt ttcgccccaa atatc
//
LOCUS       DAXISH010000008        49164 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.008, whole genome shotgun sequence.
ACCESSION   DAXISH010000008 DAXISH010000000
VERSION     DAXISH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 49164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49164
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.008"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(75..3680)
                     /gene="putA"
                     /locus_tag="ACFOV4_000462"
     CDS             complement(75..3680)
                     /gene="putA"
                     /locus_tag="ACFOV4_000462"
                     /EC_number="1.2.1.88"
                     /EC_number="1.5.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0004657 - proline dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010133 - proline catabolic process to
                     glutamate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional proline dehydrogenase/L-glutamate
                     gamma-semialdehyde dehydrogenase PutA"
                     /protein_id="HFC7618544.1"
                     /translation="MFHFAFPAQTALRQAITDAYRRNEIEAVQDMLQRAQMSDEERNA
                     ASELARRLVTQVRAGRTKAGGVDALMHEFSLSSEEGIALMCLAEALLRIPDNATRDRL
                     IADKISDGNWKSHLNNSPSLFVNAAAWGLLITGKLTATNDRQMSSALSRLISKGGAPL
                     IRQGVNYAMRLLGKQFVTGQTIEEALQNGKEREKMGYRFSFDMLGEAAYTQADADRYY
                     RDYVEAIHAIGKDAAGQGVYEGNGISVKLSAIHPRYSRAQHGRVMGELLPRLKELFLL
                     GKKYDIGINIDAEEANRLELSLDLMEALVSDPDLAGYKGIGFVVQAYQKRCPFVIDYL
                     IDLARRNNQKLMIRLVKGAYWDSEIKWAQVDGLNGYPTYTRKVHTDISYLACARKLLS
                     AQDAVFPQFATHNAYTLGAIYQMGKGKDFEHQCLHGMGETLYDQVVGPQNLGRRVRVY
                     APVGTHETLLAYLVRRLLENGANSSFVNQIVDENISIDTLIRSPFDTIAEQGIHLHNA
                     LPLPRDLYGKCRLNSQGVDLSNENVLQQLQEQMNKAAAQDFHAASIVNGKARDVGEAQ
                     PIKNPADHDDIVGTVSFADAALAQEAVGAAVAAFPEWSATPAAERAACLRRFADLLEQ
                     HTPALMMLAVREAGKTLNNAIAEVREAVDFCRYYANEAEHTLPQDAKAVGAIVAISPW
                     NFPLAIFTGEVVSALAAGNTVIAKPAEQTSLIAGYAVSLMHEAGIPTSALQLVLGAGD
                     VGAALTNDARIGGVIFTGSTEVARLINKALAKRGDNPVLIAETGGQNAMIVDSTALAE
                     QVCADVLNSAFDSAGQRCSALRILCVQEDVADRMLDMIKGAMDELVVGKPIQLTTDVG
                     PVIDAEAQQNLLNHINKMKGVAKSYHEVKTAADVDSEKSTFVRPILFELNNLNELQRE
                     VFGPVLHVVRYRADKLDSVIDQINSKGYALTHGVHSRIEGTVRHIRSRIEAGNVYVNR
                     NIVGAVVGVQPFGGHGLSGTGPKAGGSFYLQKLTRIPEWVAPTLSQIGQADEAALKRL
                     EALVHKLPFNAEEKKAAAAALGHARIRTLRRAETVLTGPTGERNSISWHAPKRVWVHG
                     GSLLQAFCALTELAASGVQAVVEPDSPLASYTADLEGLLLVNGKPETADISHVAALSP
                     LDSARKQELAAHDGALIRILPSENGLDILQVFEEISCSVNTTAAGGNASLMAVAD"
     gene            complement(3931..5457)
                     /gene="putP"
                     /locus_tag="ACFOV4_000463"
     CDS             complement(3931..5457)
                     /gene="putP"
                     /locus_tag="ACFOV4_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005298 - proline:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0031402 - sodium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0015824 - proline transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HFC7618545.1"
                     /translation="MNPMYITFAIYLVAVLLIGLAAYFSTRNFDDYILGGRSLGPFVT
                     AMSAGASDMSGWLLMGLPGAIYLSGLNEAWIAIGLLVGAYFNWLLVAGRLRVHTEYAN
                     NALTLPDYFFHRFGAGGHLMKVVSALIILFFFTIYCASGIVAGATLFQSLFEGMTYNQ
                     AMWLGAGATIVYTFLGGFLAVSWTDTLQASLMIFALILTPVMVYLGLGGAEQMSAAIQ
                     SVAAGTGKEYGSLFAGTTVIGIISTAAWGLGYFGQPHILARFMAAESAKSLVSARRIG
                     MTWMALCLAGAVAVGYFGIAYFGANPDKVSSMSGNHERIFIALSTLLFNPWIAGIILS
                     AILAAVMSTLSCQLLVCSSAITEDFYKGFLRKNAQQSELVWVGRLMVLAIAVISILIA
                     SDPNSKVLGLVSYAWAGFGAAFGPIVILSVLWKRITAYGALSGMVAGALTVVVWAEWV
                     KKPAQAAGESGLLTMYEIVPGFIVCLIVAVLVSLFNKEPSRETQERFEKADADYRAAR
                     "
     gene            5941..6261
                     /locus_tag="ACFOV4_000464"
     CDS             5941..6261
                     /locus_tag="ACFOV4_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003763371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory factor UbiK family protein"
                     /protein_id="HFC7618546.1"
                     /translation="MFGKQLFEEVGSKISETIVNSPAKDVEKNIKAMLGGAFNRMDLV
                     TREEFDIQQQVLIKTRTKLAALEARLAKLEAAQNPERAALEAAEAAAEEAVAEIRQQT
                     EAGE"
     gene            6275..7771
                     /locus_tag="ACFOV4_000465"
     CDS             6275..7771
                     /locus_tag="ACFOV4_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HFC7618547.1"
                     /translation="MSLALVYSRALSGMNAPLVEVEAHLANGLPHFNIVGLPDTEVKE
                     SRDRVRAAIIQSGFEFPAKKITVNLAPADLPKESGRFDLPIAIGILAASGQVAPEKLA
                     EYEFAGELALSGLLRPVRGALAMAWQGMQAKRAFVLPEENAGQAAVMRGITVYGARSL
                     GEVAAHLNGIEPLAQTECSVPQMPSEHGGQPDLCDVKGQHTARLALEIAAAGGHSLLM
                     MGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRSLLPNHQQQLDSHRPFRSPHHSAS
                     AAAMVGGGSDPRPGEISLAHHGVLFLDELPEFDRKVLEVLREPLENGEIHISRAARQA
                     VYPAKFQLVAAMNPCPCGYLGHPVKPCRCTPESVARYRSKISGPLLDRIDLTIEVPSL
                     SAAELMQQEAGESSASVLERVIAARDKQYARQGKVNAALSVSELDSQARIQKEAQEAL
                     GGLLEKLSLSARSFHRIMRVARTLADLAGDEEVGRSHVMKAIGFRRAL"
     gene            7877..8740
                     /gene="ftsN"
                     /locus_tag="ACFOV4_000466"
     CDS             7877..8740
                     /gene="ftsN"
                     /locus_tag="ACFOV4_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HFC7618548.1"
                     /translation="MNKFSQSGKGLSGFFFGLILATVIIAGILFYLNQSGQNAFKIPV
                     PSKQPAETEILKPKNQPKEDIQPEPADQNALSEPDAAKEAEQSDAEKAADKQPVADKA
                     DEVEEKADEPEREKSDGQAVRKKALTEEREQTVGEKAQKKDAETVKKQAVKPSKETEK
                     KASKEEKKAEKEKVAPKPTPEQILNSGSIEKARSAAAKEVQKMKTPDKAEATHYLQMG
                     AYADRRSAEGQRAKLAILGISSKVVGYQAGHKTLYRVQSGNMSADAVKKMQDELKKHE
                     VASLIRSIESK"
     gene            8743..9387
                     /locus_tag="ACFOV4_000467"
     CDS             8743..9387
                     /locus_tag="ACFOV4_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HFC7618549.1"
                     /translation="MKLKHLLPLLLSAALSAQAYALTEGEDYLVLDKPIPQEQSGKIE
                     VLEFFGYFCVHCHHFDPLLLKLGKALPSDAYLRTEHVVWQPEMLGLARMAAAVNLSGL
                     KYQANPAVFKAVYEQKIRLENRAVAGKWALSQKGFDGKKLMRAYDSPEAAAAALKMQK
                     LTEQYRIDSTPTVIVGGKYRVIFNNGFDGGVHTIKELVAKVREERKRQTPAVQK"
     gene            9420..10241
                     /locus_tag="ACFOV4_000468"
     CDS             9420..10241
                     /locus_tag="ACFOV4_000468"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFC7618550.1"
                     /translation="MDFLIVLKALMMGLVEGFTEFLPISSTGHLIVFGNLIGFHSNHK
                     VFEIAIQLGAVLAVVFEYRQRFSNVLHGLGKDRKANRFVLNLAIAFIPAAVMGLLFGK
                     QIKEYLFNPLSVAVMLVLGGFFILWVEKRQSRAEPKIADVDALRPIDALMIGVAQVFA
                     LVPGTSRSGSTIMGGMLWGIERKTATEFSFFLAVPMMVAATAYDVLKHYRFFTLHDVG
                     LILIGFIAAFVSGLVAVKALLRFVSKKNYIPFAYYRIVFGIAIIILWLSGWISWE"
     gene            complement(10523..10598)
                     /locus_tag="ACFOV4_000469"
     tRNA            complement(10523..10598)
                     /locus_tag="ACFOV4_000469"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10563..10565),aa:Ala,seq:ggc)
     gene            complement(10606..10682)
                     /locus_tag="ACFOV4_000470"
     tRNA            complement(10606..10682)
                     /locus_tag="ACFOV4_000470"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10646..10648),aa:Met,seq:cat)
     gene            complement(10814..12004)
                     /locus_tag="ACFOV4_000471"
     CDS             complement(10814..12004)
                     /locus_tag="ACFOV4_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC7618551.1"
                     /translation="MSGNPINLHKLTLIMPLPLPSPEARQFSLKLQTLIAEKIGKHGN
                     WIPFSRFMELVLYAPQYGYYTGGSHKIGNTGDFITAPTLTSLFAQTLARQLQELLSQT
                     AGNIYEFGAGTGQLAADLLGSISDGISRYYIIEISPELAARQKNLIQARAPEASQKVV
                     HLTALPEAFDGIIIGNEVLDAMPVEIVRKNEGGSFEHVGVCLDNDRFTYSARPLHDLQ
                     LSALASLYFPQTDYPYTSELHPQQYAFIRTLASRLERGGMIFIDYGFDAAQYYHPQRN
                     QGTLIGHYRHHVIHNPFDFIGLADLTAHVNFTDIAQAGTDAGLDLIGYLPQSHFLLNL
                     GITELLAQTGKTDSAAYIREAAAVQKLIDQHEMGELFKVIAFGKNIGVDWAGFRFGDI
                     CHKL"
     gene            12310..12765
                     /gene="mraZ"
                     /locus_tag="ACFOV4_000472"
     CDS             12310..12765
                     /gene="mraZ"
                     /locus_tag="ACFOV4_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFC7618552.1"
                     /translation="MFGGAHELSIDSKGRLAVPAKFRDILSRLYTPAVVVTLESKHKL
                     LMYPVAEWEKVAAQLLNLKVADNPVLRRFQNLLLHNAEILEWDSAGRVLLPAGLRKRV
                     DFDREVVLVGRANRLELWGREQWEAEMVQALDDDPDELAFQLGQTDLQL"
     gene            12762..13748
                     /gene="rsmH"
                     /locus_tag="ACFOV4_000473"
     CDS             12762..13748
                     /gene="rsmH"
                     /locus_tag="ACFOV4_000473"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFC7618553.1"
                     /translation="MSGAESYRHITVLLNEAVDALAVREDGVYVDGTFGRGGHSRLIL
                     SRLGDAGRLIVFDKDPQAIAVAEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGAL
                     FDLGISSPQIDDGSRGFSFRFDAPLDMRMDTTRGMSAAEWIAVASEQDLHEVIKNYGE
                     ERFSRQIARAIVAQRAESPIDTTRKLAQIVAQNVRTRERGQDPATRTFQAVRIFINRE
                     LEEVGAVLPQVMCRLKEGGRLAVIAFHSLEDRIVKQFVKKYSQHAPLPRWAAVREADL
                     PEPPLKIVGRALKPGEAEIAANPRARSAVLRVAERTAGSIPEQSQRKTSEWQ"
     gene            13745..14008
                     /gene="ftsL"
                     /locus_tag="ACFOV4_000474"
     CDS             13745..14008
                     /gene="ftsL"
                     /locus_tag="ACFOV4_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFC7618554.1"
                     /translation="MNKLNFLLLLAVCVSAFSVVMQQNQYRLNFTALDKAKKQEIALE
                     QDYAQMRLQQARLANHEAIRAAAEKQNLHPPVSGNTFMVAHQR"
     gene            14069..15814
                     /locus_tag="ACFOV4_000475"
     CDS             14069..15814
                     /locus_tag="ACFOV4_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFC7618555.1"
                     /translation="MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIA
                     RGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSDRNGAVLALSAPTESLFAVPKEM
                     KEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV
                     FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIV
                     DSLDSPRNKAPKNGKDIILSLDQRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEIL
                     ALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKALDAGKTDLNERLNT
                     QPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRM
                     HSGFPGETAGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFE
                     KQAVAPQGKRIFKESTAREVRNLMVSVTEPGGTGTAGAVDGFDVGAKTGTARKFVNGR
                     YADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGSLNILGI
                     SPTKPLTAAAVKTPS"
     gene            15839..17317
                     /locus_tag="ACFOV4_000476"
     CDS             15839..17317
                     /locus_tag="ACFOV4_000476"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HFC7618556.1"
                     /translation="MFSKLTPLAETGIPTLSCANAAGRLLHSDSRQIKQGDIFVACPG
                     EYADGRSYIPAAVANGAAFVFWDDDGKFAWNPEWKVPNQGIKDLKHRAGILAAQVYGN
                     VSDGLKFWGVTGTNGKTSITQWLAQAADLLGEKTAIVGTVGNGFWGALEETTHTTPAP
                     VDVQTLLYRFRQQGATVAAMEVSSHGLDQSRVNGVSFRSAIFTNLTRDHLDYHGTMEA
                     YGAIKSRLFYWHGLKHAVINVDDEYGAELVGRLKKDCPDLAVYSYGFSEHADIRIIDF
                     TASSDGIAAVFQTPWGEGKCRTRLLGRFNAQNLAACIALLCANGYPLDNVLDVLAKIR
                     PASGRMDCIMNSGKPLVVVDYAHTPDALEKALATLQEIKPQGAALWCVFGCGGNRDRG
                     KRPLMGAAAVQGADKVVVTSDNPRLENPHDIINDILPAVPAPECVEADRAAAIRYAVE
                     QAAANDIILIAGKGHENYQDVQGVKHRFSDLEIVGQALLTRK"
     gene            17340..18986
                     /locus_tag="ACFOV4_000477"
     CDS             17340..18986
                     /locus_tag="ACFOV4_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HFC7618557.1"
                     /translation="MKQSARIKNMDQTLKNTLGICALLAFCFGAAIASGYHLEYEYGY
                     RYSAVGALASVVFLLLLARGFPRVSSVVLLIYVGTTALYLPVGWLYGAPSYQIVGSIL
                     ESNPAEAREFVGNLPGSLYFVQALFFIFGLTVWKYCVSGGVFADVKNYKRRSKIWLTI
                     LLTLILSCAVMDKIASDKDLREPDAGLLLNIFDLYYDLASAPAQYVAKRAHILEAAKK
                     ASTWHIRHVAPKYKNYVVVIGESARSDYMNVYGFPLPDTPFLSQTKGLLINGYQSTAH
                     ATNLSLPQTLGLPGEPNNNIVSLAKQAGFRTAWLSNQGMLGHFANEISTYALRSDYPW
                     FTQRGDYGKSAGLSDRLLLPAFKRVLIGNAGTKPRLIVMHLMGSHSDFCTRLDKDARR
                     FQYQTEKISCYVSTIAQTDKFLEDTVKILNENKESWSLVYFSDHGLMHVGKGGERTLT
                     HGAWKRQSYGVPLVKISSDDTRREMIKVRRSAFNFLRGFGSWTGIETDELPDDGYDFW
                     GNVPDVQGEGNNLAFIDGLPDDPAPWYAGKGKSTKNTSKK"
     gene            19111..20469
                     /gene="murF"
                     /locus_tag="ACFOV4_000478"
     CDS             19111..20469
                     /gene="murF"
                     /locus_tag="ACFOV4_000478"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFC7618558.1"
                     /translation="MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRAGDVFFALA
                     GGRFDAHDFVEDVLAAGAAAVVVSREDCVAMDGALKVDDTLTALQMMAKAWRENVDPF
                     VFGITGSGGKTTVKEMLAAVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLNEKHRYAV
                     IEMGMNHFGELAVLTQIAKPDAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDG
                     MALIPQEDANMAVFKTATLNLNTRTFGIDSGDVHAENIVLKPLSCEFDLVCGDERAAV
                     VLPVPGRHNVHNAAAAAALSLAAGLSLNDVAEGLKGFSNIKGRLNVKSGIKGATLIDD
                     TYNANPDSMKAAIDVLARMPAPRIFVMGDMGELGEDEAAAMHAEVGAYARDQGIEAAY
                     FVGDNSVEAAEKFGADGLWFAAKDPLIQVLRHDLPERATVLVKGSRFMQMEEVVEALE
                     DK"
     gene            20472..20648
                     /locus_tag="ACFOV4_000479"
     CDS             20472..20648
                     /locus_tag="ACFOV4_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618559.1"
                     /translation="MKSRRFFKALLLIAALVGAFYAGMQTQAYLYEDLCLDLGGGKNP
                     GSYPICVIEKVPAR"
     gene            20895..21977
                     /gene="mraY"
                     /locus_tag="ACFOV4_000480"
     CDS             20895..21977
                     /gene="mraY"
                     /locus_tag="ACFOV4_000480"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFC7618560.1"
                     /translation="MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTI
                     RRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILTAITVSTLLWGNWANPYIWILLG
                     VLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAIIASLALFYLAANSANNILI
                     VPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYA
                     SGHSQFAQYLQLPYVAGANEVVIFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAA
                     LGTVAVIVRQEFVLVIMGGLFVVEAVSVMLQVGWYKKTKKRIFLMAPIHHHYEQKGWK
                     ETQVVVRFWIITIVLVLIGLSTLKIR"
     gene            22104..22484
                     /locus_tag="ACFOV4_000481"
     CDS             22104..22484
                     /locus_tag="ACFOV4_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFC7618561.1"
                     /translation="MKQTVKWLAAALIALGLNQAVWADDVSDFRENLQAAEQGDADAQ
                     NNLGAMYAEGQGVRQDDTEAVRWFRQAADQGLAQAQFNLGAMYYKGHGVRQDRALAQE
                     WLGKACQNGNQDGCDNDQRLKAGY"
     gene            22569..23906
                     /gene="murD"
                     /locus_tag="ACFOV4_000482"
     CDS             22569..23906
                     /gene="murD"
                     /locus_tag="ACFOV4_000482"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFC7618562.1"
                     /translation="MTFQNKKILVAGLGGTGISMIAYLRKNGAEVAAYDAELKPERVS
                     QIGKMFDGLVFYTGRLKDALDNGFDILALSPGISERQPDIEAFKQNGGRVLGDIELLA
                     DIVNRRGDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGNIGTPVLEAEWQREGKK
                     ADVWVLELSSFQLENTESLRPTAATVLNISEDHLDRYDDLLDYAHTKAKIFRGDGVQV
                     LNADDAFCRAMKRAGREVKWFSLEYEADFWLERETGRLKQGNEDLIATQDIPLQGLHN
                     ATNVMAAVALCEAVGLPREALLEHVKTFQGLPHRVEKIGEKNGVVFIDDSKGTNVGAT
                     AAAIAGLQNPLFVILGGMGKGQDFTPLRDALAGKAKGVFLIGVDAPQIRRDLDGCGLN
                     MTDCATLEEAVQTAYAQAEACDIVLLSPACASFDMFKGYAHRSEVFIEAFKAL"
     gene            24032..25357
                     /locus_tag="ACFOV4_000483"
     CDS             24032..25357
                     /locus_tag="ACFOV4_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFC7618563.1"
                     /translation="MQTDWQVVFLKISEVLVKVGDSVHTLLLDRPIVRDGRKFDAPLL
                     WMVVLMTAFSLLMIYSASVYLASKEGGDQFFYLTRQAGFVVAGLIASGLLWFLCRMRT
                     WRRLVPWIFALSGLLLVVVLIAGREINGATRWIPLGPLNFQPTELFKLAVILYLASLF
                     TRREEVLRSMESLGWQSIWRGTANLIMSATNPQARRETLEMYGRFRAIILPIMLVAFG
                     LVLIMVQPDFGSFVVITVIAVGMLFLAGLPWKYFFVLVGSVLGGMVLMITAAPYRVQR
                     VVAFLDPWKDPQGAGYQLTHSLMAIGRGEWFGMGLGASLSKRGFLPEAHTDFIFAIIA
                     EEFGFFGMCVLIFCYGWLVVRAFSIGKQSRDLGLTFNAYIASGIGIWIGIQSFFNIGV
                     NIGALPTKGLTLPLMSYGGSSVFFMLISMMLLLRIDYENRRKMRGYRVE"
     gene            25361..26428
                     /gene="murG"
                     /locus_tag="ACFOV4_000484"
     CDS             25361..26428
                     /gene="murG"
                     /locus_tag="ACFOV4_000484"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFC7618564.1"
                     /translation="MGGKTFMLMAGGTGGHIFPALAVADSLRARGHHVIWLGSKDSME
                     ERIVPQYGIRLETLAIKGVRGNGIKRKLMLPFTLYQTVREAQRIIRKHRVECVIGFGG
                     FVTFPGGLAAKLLGVPIVIHEQNAVAGLSNRHLSRWAKRVLYAFPKAFSHEGGLVGNP
                     VRADISNLPVPAERFQGREGRLKILVVGGSLGADVLNKTVPQALALLPDNARPQMYHQ
                     SGRGKLGSLQADYDALGVKAECVEFITDMVSAYRDADLVICRAGALTIAELTAAGLGA
                     LLVPYPHAVDDHQTANARFMVQAEAGLLLPQTQLTAEKLAEILGSLNREKCLKWAENA
                     RTLALPHSADDVAEAAIACAA"
     gene            26583..27992
                     /gene="murC"
                     /locus_tag="ACFOV4_000485"
     CDS             26583..27992
                     /gene="murC"
                     /locus_tag="ACFOV4_000485"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFC7618565.1"
                     /translation="MMKNRVTNIHFVGIGGVGMSGIAEVLHNLGFKVSGSDQARNAAT
                     EHLGSLGIQVYPGHTAEHVNGADVVVTSTAVKKENPEVVAALEQQIPVIPRALMLAEL
                     MRFRDGIAIAGTHGKTTTTSLTASILGAAGLDPTFVIGGKLNAAGTNARLGKGEYIVA
                     EADESDASFLHLTPIMSVVTNIDEDHMDTYGHSVEKLHQAFIDFIHRMPFYGKAFLCI
                     DSEHVRAILPKVSKPYATYGLDDTADIYATDIENVGAQMKFTVHVQMKGHEQGSFEVV
                     LNMPGRHNVLNALAAIGVALEVGASVEAIQKGLLGFEGVGRRFQKYGDIKLPNGGTAL
                     LVDDYGHHPVEMAATLAAARGAYPEKRLVLAFQPHRYTRTRDLFEDFTKVLNTVDALV
                     LTEVYAAGEEPIAAADSRALARAIRVLGKLEPIYCENVADLPEMLLNVLQDGDIVLNM
                     GAGSINRVPAALLELSKQI"
     gene            28106..29020
                     /locus_tag="ACFOV4_000486"
     CDS             28106..29020
                     /locus_tag="ACFOV4_000486"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003764621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFC7618566.1"
                     /translation="MQNFGKVAVLMGGFSSEREISLDSGTAILNALKSKGIDAYAFDP
                     KETPLSELKAQGFQTAFNILHGTYGEDGAVQGALELLGIPYTGSGVAASAIGMDKYRC
                     KLIWQALGLPVPEFAVLHDDTDFDAVEEKLGLPMFVKPAAEGSSVGVVKVKEKGRLKS
                     VYEELKHLQGEIIAERFIGGGEYSCPVLNGKGLPGIHIIPATEFYDYEAKYNRDDTIY
                     QCPSEDLTEAEESLMRELAVRGAQAIGAEGCVRVDFLKDTDGKLYLLEINTLPGMTSH
                     SLVPKSAAVTGVGFADLCIEILKTAHVG"
     gene            29010..29738
                     /locus_tag="ACFOV4_000487"
     CDS             29010..29738
                     /locus_tag="ACFOV4_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFC7618567.1"
                     /translation="MWDNAEAMERLTRWLLVMMAMLLAASGLVWFYNSNHLPVKQVSL
                     KGNLVYSDKKALGSLAKEYIHGNILRTDINGAQEAYRRYPWIASVMVRRRFPDTVEVV
                     LTERKPVARWGDHALVDGEGNVFEARLDRPGMPVFRGAEGTSAEMLRRYDEFSTVLAK
                     QGLGIKEMTYTARSAWIVVLDNGITVRLGRENEMKRLRLFTEAWQHLLRKNKNRLSYV
                     DMRYKDGFSVRYASDGLPEKESEE"
     gene            29824..31068
                     /gene="ftsA"
                     /locus_tag="ACFOV4_000488"
     CDS             29824..31068
                     /gene="ftsA"
                     /locus_tag="ACFOV4_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFC7618568.1"
                     /translation="MEQQQRYISVLDIGTSKVLALIGEVQDDDKINIVGLGQAPSRGL
                     RAGMVTNIDATVQAIRQAVNDAELMADTKITHVTTGIAGNHIRSLNSQGVVKIKDGEV
                     TQADIDRAIETAKAINIPPDQKILDAVVQDYIIDTQLGVREPIGMSGVRLDTRVHIIT
                     GASTAVQNVQKCIERCGLKSDQIMLQPLASGQAVLTEDEKDLGVCVIDIGGGTTDIAV
                     YMNGAIRHTSVIPAGGNLITKDLSKSLRTPLDAAEYIKIHYGVASCDTEGLGEMIEVP
                     GVGDRTSRQVSSKVLAAIISARIQEIFGVVLGELQKSGFPKEVLNAGIVLTGGVSMMT
                     GIVEFAEKIFDLPVRTGAPQEMGGLSDRVRTPRFSTAIGLLHAACKLEGNLPQPENGA
                     VQEREGGGGLLARLKRWIENSF"
     gene            31187..32365
                     /gene="ftsZ"
                     /locus_tag="ACFOV4_000489"
     CDS             31187..32365
                     /gene="ftsZ"
                     /locus_tag="ACFOV4_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFC7618569.1"
                     /translation="MEFVYDVAESAVSPAVIKVIGLGGGGCNAINNMVANNVRGVEFI
                     SANTDAQSLAKNHAAKRIQLGTNLTRGLGAGANPDIGRAAAQEDREAIEEAIRGANML
                     FITTGMGGGTGTGSAPVVAEIAKSLGILTVAVVTRPFAYEGKRVHVAQAGLEQLKEHV
                     DSLIIIPNDKLMTALGEDVTMREAFRAADNVLRDAVAGISEVVTCPSEIINLDFADVK
                     TVMSNRGIAMMGSGYAQGIDRARMATDQAISSPLLDDVTLDGARGVLVNITTAPGCLK
                     MSELSEVMKIVNQSAHPDLECKFGAAEDETMSEDAIRITIIATGLKEKGAVDFVPARE
                     VEAVAPSKQEQSHNVEGMIRTNRGIRTMNLTAADFDNQSVLDDFEIPAILRRQHNSDK
                     "
     gene            32504..33814
                     /locus_tag="ACFOV4_000490"
     CDS             32504..33814
                     /locus_tag="ACFOV4_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFC7618570.1"
                     /translation="MDTSKQTLLDGIFKLKANGTTVRTELMAGLTTFLTMCYIVIVNP
                     LILGETGMDMGAVFVATCIASAIGCFVMGFVGNYPIALAPGMGLNAYFTFAVVKGMGV
                     PWQVALGAVFISGLIFILFSFFKVREMLVNALPMGLKMSIAAGIGLFLALISLKGAGI
                     IVANPATLVGLGDIHQPSALLALFGFAMVVVLGHFRVQGAIIITILTITVIASLMGLN
                     EFHGIIGEVPSIAPTFMQMDFEGLFTVSMVSVIFVFFLVDLFDSTGTLVGISHRAGLL
                     VDGKLPRLKRALLADSTAIVAGAALGTSSTTPYVESAAGVSAGGRTGLTAVTVGVLML
                     ACLMFSPLAKSVPAFATAPALLYVGTQMLRSARDIDWDDMTEAAPAFLTIVFMPFTYS
                     IADGIAFGFISYAVVKLLCRRTKDVPPMVWIVAVLWALKFWYLG"
     gene            34440..35315
                     /gene="prpB"
                     /locus_tag="ACFOV4_000491"
     CDS             34440..35315
                     /gene="prpB"
                     /locus_tag="ACFOV4_000491"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003779818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046421 - methylisocitrate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HFC7618571.1"
                     /translation="MSQHSAGARFRQAVKESNPLAVAGCVNAYFARLATQSGFKAIYL
                     SGGGVAACSCGIPDLGITTMEDVLIDARRITDNVDTPLLVDIDVGWGGAFNIARTIRN
                     FERAGVAAVHIEDQVAQKRCGHRPNKAIVSKDEMVDRIKAAVDARVDENFVIMARTDA
                     LAVEGLDAAIERAQACVEAGADMIFPEAMTDLNMYRQFADAVKVPVLANITEFGSTPL
                     YTQSELAENGVSLVLYPLSSFRAASKAALNVYEAIMRDGTQAAVVDSMQTRAELYEHL
                     NYHAFEQKLDKLFQK"
     gene            35401..36555
                     /gene="prpC"
                     /locus_tag="ACFOV4_000492"
     CDS             35401..36555
                     /gene="prpC"
                     /locus_tag="ACFOV4_000492"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050440 - 2-methylcitrate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HFC7618572.1"
                     /translation="MTETTQTPTLKPKKSVALSGVAAGNTALCTVGRTGNDLSYRGYD
                     ILDLAQKCEFEEVAHLLIHGHLPNKFELAAYKTKLKSMRGLPIRVIKVLESLPAHTHP
                     MDVMRTGVSMLGCVHPERESHPESEARDIADKLIASLGSILLYWYQYSHNGKRIEVES
                     DEETIGGHFLQLLHGKRPSESHIKAMHVSLILYAEHEFNASTFTARVIAGTGSDMYSS
                     ITGAIGALKGPKHGGANEVAYDIQKRYRNADEAEADIRERIGRKEIVIGFGHPVYTIS
                     DPRNVVIKEVARGLSKETGDMRLFDIAERLESVMWEEKKMFPNLDWFSAVSYQKLGVP
                     TAMFTPLFVISRTTGWSAHVLEQRKDGKIIRPSANYTGPEDLAFVEIEER"
     gene            36716..37504
                     /locus_tag="ACFOV4_000493"
     CDS             36716..37504
                     /locus_tag="ACFOV4_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004464335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFC7618573.1"
                     /translation="MEDLYIILALGLVAMIAGFIDAIAGGGGLITLPALLLAGIPPVS
                     AIATNKLQAAAATFSATVSFARKGLIDWKKGLPIAAASFAGGVVGALSVSLVSKDILL
                     AVVPVLLIFVALYFVFSPKLDGSKEGKARMSFFLFGLTVAPLLGFYDGVFGPGVGSFF
                     LIAFIVLLGCKLLNAMSYTKLANVACNLGSLSVFLLHGSIIFPIAATMAVGAFVGANL
                     GARFAVRFGSKLIKPLLIVISISMAVKLLTDERNPLYQMIISMF"
     gene            37582..40188
                     /gene="acnD"
                     /locus_tag="ACFOV4_000494"
     CDS             37582..40188
                     /gene="acnD"
                     /locus_tag="ACFOV4_000494"
                     /EC_number="4.2.1.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047456 - 2-methylisocitrate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0019679 - propionate metabolic process,
                     methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe/S-dependent 2-methylisocitrate dehydratase
                     AcnD"
                     /protein_id="HFC7618574.1"
                     /translation="MAANQRYRKPLPGTDLEYYDARAACEDIKPGSYDKLPYTSRILA
                     ENLVNRADKVDLPTLQSWLGQLIEGKQEIDFPWYPARVVCHDILGQTALVDLAGLRDA
                     IAEKGGDPAKVNPVVQTQLIVDHSLAVECGGYDPDAFRKNREIEDRRNEDRFHFINWT
                     KTAFENVDVIPAGNGIMHQINLEKMSPVVQVKNGVAFPDTCVGTDSHTPHVDALGVIS
                     VGVGGLEAETVMLGRASMMRLPDIVGVELTGKRQAGITATDIVLALTEFLRKERVVGA
                     FVEFFGEGARSLSIGDRATISNMTPEFGATAAMFAIDEQTIDYLKLTGRDDAQVKLVE
                     TYAKTAGLWADALKTAVYPRVLKFDLSSVTRNMAGPSNPHARFATADLAAKGLAKPYE
                     EPSDGQMPDGAVIIAAITSCTNTSNPRNVVAAALLARNANRLGLKRKPWVKSSFAPGS
                     KVAEIYLKEAGLLPEMEKLGFGIVAFACTTCNGMSGALDPKTQKEIIDRDLYATAVLS
                     GNRNFDGRVHPYAKQAFLASPPLVVAYALAGSIRFDIENDVLGVADGKEIRLKDIWPA
                     DEEIDAVVAEYVKPQQFRDVYVPMFDTGTAQKAPSPLYDWRPMSTYIRRPPYWEGALA
                     GERTLRGMRPLAILPDNITTDHLSPSNAILAVSAAGEYLAKMGLPEEDFNSYATHRGD
                     HLTAQRATFANPKLFNEMVKNEDGSVRQGSFARVEPEGETMRMWEAIETYMNRKQPLI
                     IIAGADYGQGSSRDWAAKGVRLAGVEAIVAEGFERIHRTNLIGMGVLPLQFKPDTNRH
                     TLQLDGTETYDVVGERTPRCDLTLVIHRKNGETVEVPVTCRLDTAEEVLVYEAGGVLQ
                     RFAQDFLEGNAA"
     gene            40991..42160
                     /gene="prpF"
                     /locus_tag="ACFOV4_000495"
     CDS             40991..42160
                     /gene="prpF"
                     /locus_tag="ACFOV4_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004464330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylaconitate cis-trans isomerase PrpF"
                     /protein_id="HFC7618575.1"
                     /translation="MPQIKIPAVYYRGGTSKGVFFKRSDLPEAAREAGSARDKILLRV
                     LGSPDPYGKQIDGLGNASSSTSKAVILDKSERADHDVDYLFGQVSIDKPFVDWSGNCG
                     NLTAAVGAFAIEQGLVDKGKIPSDGICTVKIWQKNIGKTIIAHVPMQNGAVLETGDFE
                     LDGVTFPAAEVQIEFLDPADGEGSMFPTGNLVDEIDVPNIGRLKATLINAGIPTVFLN
                     AADLGYTGKELQDDINNDAAALEKFEKIRAYGALKMGLISDVSEAAARAHTPKVAFVA
                     PAADYTASSGKTVNAADIDLLVRALSMGKLHHAMMGTASVAIATAAAVPGTLVNLAAG
                     GGTRKEVRFGHPSGTLRVGAAAECQDGQWTATKAVMSRSARVMMEGWVRVPEDCF"
     gene            42574..43773
                     /locus_tag="ACFOV4_000496"
     CDS             42574..43773
                     /locus_tag="ACFOV4_000496"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HFC7618576.1"
                     /translation="MSDQLILVLNCGSSSLKGAVIDRKSGSIVLSCLGERLTTPEAVI
                     TFSKDGNKRQVPLSGRNCHAGAVGMLLNELEKHGLHDRIKAIGHRIAHGGEKYSESVL
                     IDQAVMDELNACIPLAPLHNPANISGILAAQEHFPGLPNVGVMDTSFHQTMPERAYTY
                     AVPRELRKKYAFRRYGFHGTSMRYVAPEAARILGKPLEDIRMIIAHLGNGASITAIKN
                     GKSVDTSMGFTPIEGLVMGTRCGDIDPGVYSYLTSHAGMDVAQVDEMLNKKSGLLGIS
                     ELSNDCRTLEIAADEGHEGARLALEVMTYRLAKYIASMAVACGGVDALVFTGGIGENS
                     RNIRAKTVSYLDFLGLHIDTKANMDKRYGNSGIISPTDSSPAVLVVPTNEELMIACDT
                     AELVGIL"
     gene            44131..44751
                     /locus_tag="ACFOV4_000497"
     CDS             44131..44751
                     /locus_tag="ACFOV4_000497"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFC7618577.1"
                     /translation="MAQFFAVHPDNPQERLIKQAVEIVNQGGVVVYPTDSCYALGCKL
                     GDKAAMERILSIRKIDLKHHLTLMCADLSELGTYAKIDNVQFRQLKAATPGPYTFILQ
                     ATKEVPARTLHPKRKTIGLRIPDNAIAQALLGELGEPLLSCTLMLPEDGEPLTDPYEI
                     RERLEHAVDLVIDGGWCGTEPTTVVDMTDGTELVRQGCGDTAVFGL"
     gene            complement(44878..45321)
                     /locus_tag="ACFOV4_000498"
     CDS             complement(44878..45321)
                     /locus_tag="ACFOV4_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFC7618578.1"
                     /translation="MYLTQHTDYGLRVLIYTAINDDALVNISTIAVTYGISKSHLMKV
                     VTALVKGGFLHSVRGKGGGLRLAAPPDRINIGSVVRHLEPMQLVECMGENNECLITPS
                     CRLTGILGGAMKSFFTYLDGFTLQDLLNKPTYDLLYEPRIPIAVQ"
     gene            45495..45863
                     /locus_tag="ACFOV4_000499"
     CDS             45495..45863
                     /locus_tag="ACFOV4_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HFC7618579.1"
                     /translation="MKPLKRHPALIGLSRDHHHSLSLCVRLLRTPEERHRDELEPHFA
                     ELETHFREEEAKFAPIWQNVAPELKQRFEKDHARLRQMMASPEYGNAAWNTAFATTLR
                     DHARFEERELFPAAEPFLPA"
     gene            45908..47062
                     /locus_tag="ACFOV4_000500"
     CDS             45908..47062
                     /locus_tag="ACFOV4_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NnrS family protein"
                     /protein_id="HFC7618580.1"
                     /translation="MKFTKHPVWAMAFRPFYSLAALYGALSVLLWGFGYTGTHELSGF
                     YWHAHEMIWGYAGLVVVAFLLTAVATWTGQPPTRGGVLVGLTIFWLAARIAAFIPGWG
                     ASASGILGTLFFWYGAVCMALPVIRSQNQRNYVAVFALFVLGGTHAAFHVQLHNGNLG
                     GLLSGLQSGLVMVSGFIGLIGTRIISFFTSKRLNVPQIPSPKWVAQASLWLPMLTAML
                     MAHGVMPWLSAAFAFAAGVIFTVQVYRWWYKPVLKEPMLWILFAGYLFTGLGLIAVGA
                     SYFKPAFLNLGVHLIGVGGIGVLTLGMMARTALGHTGNPIYPPPKAVPVAFWLMMAAT
                     AVRMVAVFSSGTAYTHSIRTSSVLFALALLVYAWKYIPWLIRPRSDGRPG"
     gene            complement(47119..47991)
                     /locus_tag="ACFOV4_000501"
     CDS             complement(47119..47991)
                     /locus_tag="ACFOV4_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFC7618581.1"
                     /translation="MPILNHIALIGVGLIGGSFVLDLKRQGLVRTVTGIDTDRDNLER
                     ALERGVIDRASVAIDADSIGGADLVLIATPVATVPAILTALRPVLPEHTWISDVGSTK
                     SSVIEAFRRCLPDRLHRCIAAHPIAGSDRSGAQAAQFGLFRHRKLIITPHGGEHSDGI
                     ALIENLWRAVGAEIYTMDAQRHDAVFAAVSHMPHLTAFAYVHQILDHPDGQEYLKFAA
                     TGFRDFTRIASGHPAVWADICLANKDSLLQLVQGLGKQLDVLANILTTDDREALYRYF
                     EEAKTTRDRWLDGN"
     gene            48076..48888
                     /locus_tag="ACFOV4_000502"
     CDS             48076..48888
                     /locus_tag="ACFOV4_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HFC7618582.1"
                     /translation="MDKIRVAAVQMVSGVSPETNVAAMKRLVARAAEQGADWVLLPEY
                     WVLMGANDTDKLALAEPLGGGRFQTALSETAKECGVVLFGGTVPLQSPEAGKVMNTLL
                     VYGRDGKRTGLYHKMHLFGFSGLGERYAEADTIRAGGEVPHLSAEGVPVAAGICYDVR
                     FPEFFRRQLPFDVLMLPAAFTHTTGKAHWELLLRARAVENQCYVVAAAQGGLHENGRR
                     TFGHSMIVDPWGDVLDVLPEGEGVVTADIDANRLNSVRNRLPALKYRVLDAV"
BASE COUNT        11307 a        12416 c        13976 g        11465 t
ORIGIN      
        1 cactataaaa atgccgtctg aaaggttttc agacggcatt ggttcacggg ccgcgctcgg
       61 ggatttcggt aaaatcagtc ggcaaccgcc atcaggctgg cgttgccgcc ggcggctgtg
      121 gtgttgacgc tgcaagagat ttcttcaaac acttgcagga tgtcgagtcc gttttccgaa
      181 gggaggatgc ggatgagtgc gccgtcgtgg gcggcaagtt cctgtttgcg cgcgctgtcc
      241 aaaggcgaca gggcggcaac gtggctgatg tcggcggttt cgggtttgcc gttgaccagc
      301 agcagacctt ccaagtcggc ggtgtaggaa gccagcgggc tgtcgggttc gaccactgcc
      361 tgtacgccgg aggcggcaag ttcggttagg gcgcagaagg cttgcaggag gctgccgccg
      421 tgtacccaga cgcgttttgg cgcgtgccat gagatgctgt tgcgctcgcc ggtcgggccg
      481 gtaaggacgg tttcggcacg gcgcagggtg cggatgcggg cgtgtcccaa agcggccgct
      541 gcggcttttt tctcttcggc gttgaacggc agtttgtgaa ccagtgcttc gaggcgtttg
      601 agcgcggctt cgtctgcctg tccgatttgg ctcagggtcg gggcaaccca ttcggggatg
      661 cgggtcagtt tttgcaggta gaacgaaccg cctgctttgg ggcctgtgcc ggacagaccg
      721 tgtccgccga agggctgtac gccgacgact gcgccgacga tgttgcggtt gacgtaaacg
      781 ttgccggctt cgatgcggct gcggatgtgg cgtactgtgc cttcgatgcg gctgtgtacg
      841 ccgtgggtca gggcgtagcc tttgctgttg atttggtcga tgacgctgtc gagtttgtcg
      901 gcgcggtagc ggacgacgtg caggacggga ccgaagactt cgcgttgcag ttcgttgagg
      961 ttgttcaatt caaacaggat ggggcggacg aacgtggatt tttcggaatc gacatcggca
     1021 gcggttttga cttcgtggta agacttggca acgcctttca ttttgttgat gtggttcaac
     1081 aggttttgct gtgcttcggc atcgatgacg gggccgacat cggtagtgag ctgaatcggt
     1141 ttgccgacga cgagttcgtc catcgcgcct ttgatcatgt cgagcatacg gtcggcaacg
     1201 tcttcttgga cgcacaagat acgcagggcg gagcagcgtt gtcccgcgct gtcgaaggcg
     1261 gagttcaata cgtcggcgca gacttgttcg gcaagtgcgg tggaatcgac aatcatggcg
     1321 ttttgtccgc cggtttcggc aatcaggacg ggattgtcgc cgcgtttggc aagggctttg
     1381 ttgatcaggc gcgccacttc ggtcgagccg gtgaaaatca cgccgccgat gcgggcatcg
     1441 ttggtcaatg ccgcacccac gtcgcctgcg ccgaggacga gttgcagggc ggaagtcggg
     1501 atgccggctt cgtgcatgag ggaaacggca taaccggcaa tcaggctggt ttgttcggcg
     1561 ggtttggcga tgacggtgtt gcctgccgcc aatgcggaaa cgacttcgcc ggtaaagatg
     1621 gcgagcggga agttccacgg gctgatggcg acaatcgcgc cgacggcttt tgcgtcttga
     1681 ggcagggtat gttcggcttc gtttgcgtag tagcggcaga aatcgacggc ttcgcgcact
     1741 tcggcaatgg cgttgttcag cgttttgcct gcttcgcgca cggcaagcat catcagcgcg
     1801 ggggtgtgct gttcgagcag gtcggcgaaa cggcgcaggc aggcggcgcg ttcggcggca
     1861 ggtgtcgcac tccattcggg gaacgcggca acggctgcgc caaccgcttc ttgggcaagc
     1921 gcggcatcgg caaagctgac tgtgccgacg atgtcgtcgt ggtcggcagg gtttttaatc
     1981 ggttgcgctt cgccgacatc gcgggctttg ccgttgacga tggatgcggc gtggaagtct
     2041 tgcgcggcgg ctttgttcat ctgttcttga agctgctgca atacgttttc gttgctcaag
     2101 tccacgcctt gcgagttcag acggcatttg ccgtacaaat cgcgcggcag cggcagggcg
     2161 ttgtgcaggt ggatgccttg ttcggcgatg gtgtcgaacg ggctgcggat gagcgtgtcg
     2221 atgctgatgt tttcatcgac gatttggttg acgaaagacg agttcgcgcc gttttccaac
     2281 aggcggcgca ccaagtaggc gagcagggtt tcgtgtgtgc cgaccggggc gtacacgcgc
     2341 acgcggcggc ctaagttttg cgggccgacg acttggtcgt acagggtttc gcccatgccg
     2401 tgcagacatt ggtgttcaaa gtctttgcct ttgcccattt ggtagattgc gcccaaggtg
     2461 taggcgttgt gggtggcgaa ttgcggaaat accgcgtctt gcgcggaaag cagtttgcgc
     2521 gcgcaggcga ggtaggagat gtcggtgtgg actttgcggg tgtaggtcgg atagccgttc
     2581 aagccgtcca cttgcgccca tttgatttcg ctgtcccaat acgcgccttt gacgaggcgg
     2641 atcattagtt tttggttgtt gcggcgggca aggtcgatca ggtagtcgat aacgaacgga
     2701 caacgttttt ggtaggcttg aacaacgaaa ccgatgcctt tgtagcctgc caaatcggga
     2761 tcggaaacga gtgcctccat caaatccaaa gacagctcca gacggttggc ttcttcggca
     2821 tcgatgttga taccgatatc gtatttttta cccaaaagga acagctcttt caggcgcggc
     2881 aacagttcgc ccatcacacg gccgtgttgg gcgcgcgagt agcgcggatg tatggcggag
     2941 agtttgacgg aaatgccgtt gccttcgtaa acgccttgtc ctgccgcatc tttgccgatg
     3001 gcgtggatgg cttcgacata gtcgcggtag tagcggtcgg catcggcttg ggtgtaggcg
     3061 gcttcgccca acatatcgaa ggagaagcgg tagcccattt tttcgcgttc tttgccgttt
     3121 tgcagggctt cttcaatggt ctgtccggtt acgaactgtt tgcccaacag gcgcatggcg
     3181 taatttacgc cttggcggat gagcggtgcg ccgcctttgc tgatcaggcg gctgagtgcg
     3241 gaactcattt gtctgtcgtt tgtggcggtc agtttgccgg taatcagcag gccccaggcg
     3301 gcggcgttga cgaagaggga agggctgttg ttcaaatggc ttttccagtt gccgtctgaa
     3361 atcttgtcgg caatcaggcg gtcgcgcgtg gcgttgtcgg ggatacgcag cagggcttct
     3421 gccagacaca tcagcgcgat gccttcttcg ctggagagtg aaaactcgtg catcagcgca
     3481 tccacgccgc cggctttggt gcggccggcg cggacttggg taaccaaacg gcgggcaagc
     3541 tcggaggcgg cgttgcgctc ttcgtcgctc atctgtgcac gttgcaacat atcctgtacg
     3601 gcttcgattt cattacggcg gtaggcatcg gttatcgctt ggcgcagggc agtttgtgcc
     3661 ggaaatgcaa aatgaaacat tttttggatt ctccaaagtt tttcgggggg ttcagacggc
     3721 atcggtgcgg tctgaatacg gtaatatcgt aataaatccg cagatgaaat acaaggcttc
     3781 aaatgcgggc agggtaggtg cttccgtttc tttgaaaatg aaacgggtaa aacacaaata
     3841 aggcctgtat gcaggcaagg tttatttgtg tttgacccgg aaacgggttc agacggcacg
     3901 aaccgggatg ccgtgccgtc tgaaaggggt ttatcgggcg gcgcggtaat ctgcgtcggc
     3961 tttttcaaag cgttcttggg tttcgcgcga aggttctttg ttgaacaggg aaaccaacac
     4021 ggcaacgatc aagcaaacaa taaagcccgg gacgatttcg tacatcgtca acaagccgct
     4081 ttcgcctgcc gcttgagccg gttttttcac ccattccgcc catacgacca cggttaaggc
     4141 acctgcaacc atacccgaca acgcgccgta ggcagtgatg cgtttccaca atacggacag
     4201 aatcacaatc gggccgaatg ccgcaccgaa acctgcccac gcgtaagaca ccagtcccaa
     4261 tactttgctg ttcggatcgg aagcaatcag gatggaaatc acggcaatcg ccaagaccat
     4321 caggcggccg acccatacca gttccgactg ttgcgcgttt ttacgcaaaa agcctttgta
     4381 gaagtcttcg gtaatcgcgc tggagcaaac caaaagctgg caggacaggg tggacatcac
     4441 cgccgccaaa atcgcgctca aaataatgcc ggcgatccaa gggttgaaca gcagggtgga
     4501 aagcgcgatg aagatgcgtt cgtggttgcc gctcatagaa gaaactttgt cgggatttgc
     4561 accgaaatac gcaatgccga aataaccgac cgctaccgcg cccgcaaggc acaacgccat
     4621 ccaagtcatg ccgatgcggc gtgcggatac cagcgatttc gcgctttcgg ccgccataaa
     4681 gcgcgccaaa atgtgcggct gtccgaaata gcccaagccc catgcggcgg tggaaatgat
     4741 gccgatgacg gtcgtaccgg caaacaggct gccgtattct ttgcccgtgc ctgcggcgac
     4801 gctttgaatc gcggcagaca tctgttccgc gccgcccaag cccagataga ccatcaccgg
     4861 cgttaaaatc agggcgaaaa tcatcaaaga tgcttgcagc gtatccgtcc agctgactgc
     4921 caagaaaccg cccaagaagg tatagacgat ggtcgcgccc gcacccagcc acattgcctg
     4981 gttgtaagtc ataccttcaa acagactttg gaacagggtt gcgccggcca caatgccgga
     5041 agcacagtaa attgtgaaga aaaacaagat aattagtgcg gaaaccactt tcatcaagtg
     5101 tccgcccgcg ccgaagcggt ggaagaaata atccggcagc gtcagcgcat tgttggcgta
     5161 ttcggtatgc acgcgcaggc ggcccgccac caagagccag ttgaaatacg cgccgaccaa
     5221 gaggccgatg gcaatccaag cctcattcaa accgctcagg taaatcgcgc ccggcagacc
     5281 catcagcagc cagccggaca tatcggacgc gcctgccgac atcgcggtaa caaacgggcc
     5341 taggctgcgc ccgcccaaaa tataatcgtc gaaattgcgc gtagaaaaat aggcggcaag
     5401 cccgatgaga aggactgcaa ccagatagat tgcaaaagta atgtacatgg gattcatgtg
     5461 ctattcctcg tctaaaactt cagaattaca ggctttgaaa ttgcaagcaa cttgcgcctg
     5521 aaatgttttt ctaaataaaa gtacaacgga aaatccggat acccgaaagg gggattcgga
     5581 taaattatct tcaatcacaa taagatatgt aataaaacta tatgaaattg taaataatcc
     5641 gtttcagcat aacccaattt ctgttgtttg caaagcactt aatggcttaa aaagccgagt
     5701 ttgaaacgat gcgcgtcgga aaaatcattt aaaacagtat attgttttgt agtgtcttgt
     5761 aatctggcgt tgcgcggaat atgaaatccg ttttcaggcg gcaggtgttt tgaggtgtaa
     5821 tttagcaacc gcaaaggagg cgcggtatgt tttgccgatt atccgccgcc cgttttcaga
     5881 cggcattttt ccttatacaa tagccgattg aatttgatat gttcaggaag gatacagatt
     5941 atgttcggca agcagctttt tgaagaagtc ggttcgaaaa tcagcgaaac catcgtcaac
     6001 agccctgcca aagatgtgga aaaaaatatt aaggcgatgc tgggcggcgc gttcaaccgt
     6061 atggatttgg ttacgcgcga agaattcgac atccagcagc aggttttaat caaaacccgt
     6121 accaaactgg cggctttgga agcgcgtttg gcaaaactcg aagccgcgca aaatcccgaa
     6181 cgggcagcat tggaagcggc tgaagccgct gccgaagaag ccgtcgccga aatcaggcag
     6241 caaaccgaag ccggcgaata aggccgtctg aaatatgtcg cttgccttgg tttacagccg
     6301 cgccttgagc ggtatgaatg cgccgttggt cgaagtggaa gcccaccttg ccaacggcct
     6361 gccacatttc aacatcgtcg gactgcccga tacggaagtc aaagaaagtc gcgaccgcgt
     6421 ccgtgccgcc attattcaaa gcggttttga attccccgcc aaaaaaatca ccgtcaacct
     6481 cgcccccgcc gacctgccca aagagtcggg gcgtttcgat ttgccgattg caatcggcat
     6541 ccttgccgca tcggggcagg ttgcgcccga aaaactggcg gaatacgagt ttgcggggga
     6601 attggcactg tcggggctgt tgcgccccgt gcgcggcgcg ttggcgatgg cgtggcaggg
     6661 tatgcaggca aaacgtgcat ttgttttgcc tgaagaaaac gcaggacaag ccgccgtgat
     6721 gcgcggcatt accgtttacg gcgcgcgctc tttgggcgaa gtcgccgccc atttgaacgg
     6781 tatcgaacct ttggcgcaaa ccgaatgttc cgtaccgcaa atgccgtctg aacatggcgg
     6841 acaacctgat ttgtgtgatg tgaaaggtca gcacactgcc cgccttgctt tggaaatcgc
     6901 tgccgcaggc ggacacagcc tcttgatgat gggtccgccg ggaacgggca agtctatgct
     6961 ctcccaacgg ctgccaggca tcctgccgcc gctgaccgaa gacgaattgg ttgaagtttg
     7021 ggcattgcgt tcgctcctgc ccaaccacca gcaacaactc gacagccacc gtcctttccg
     7081 cagtccgcat cacagtgcca gcgcggcggc tatggtcggc ggcggttccg acccgcgtcc
     7141 gggcgagatt tcattggcgc accacggcgt attgtttttg gacgagctgc ccgagttcga
     7201 ccgcaaagtt ttggaagttt tgcgcgaacc gttggaaaac ggcgaaatcc acatttcccg
     7261 cgcggcgcgc caagccgtct atcctgccaa attccaactt gttgccgcca tgaacccctg
     7321 cccgtgcggt tatctcgggc atcccgtcaa accctgccgc tgcacgcccg aaagcgtcgc
     7381 gcgttaccgc agcaaaattt ccggcccgct gctcgaccgc atcgatttga ccatcgaagt
     7441 ccccagcctg tccgccgccg aactgatgca gcaggaagcg ggtgaaagca gcgcgtccgt
     7501 tttggaacgc gttatcgccg cccgcgacaa acaatacgcg cggcagggca aagtcaacgc
     7561 cgctttgagt gtcagcgaac tcgattccca agcccgcatt caaaaagaag cgcaggaagc
     7621 attgggcggc ctgctggaaa aactctccct ttccgcccgc agcttccacc gcattatgcg
     7681 cgtggcgcgt acattggcgg atttggcggg cgacgaagaa gtcggcagaa gccacgtcat
     7741 gaaagccata ggtttccgtc gtgctttata ggaatgggaa tggaagcagg ttttgcccaa
     7801 atatggcgat attgttagaa tatccgcccg taagcaaacg gcgttaatgc cgtctgaaac
     7861 acattaaggt atgtttatga acaaattttc ccaatccgga aaaggtctgt ccggtttttt
     7921 cttcggtttg atactggcga cggtcattat tgccggtatt ttgttttatc tgaaccagag
     7981 cggtcaaaat gcgttcaaaa tcccggttcc gtcgaagcag cctgcagaaa cggaaatcct
     8041 gaaaccgaaa aaccagccta aggaagacat ccaacctgaa ccggccgatc aaaacgcctt
     8101 gtccgaaccg gatgctgcga aagaggcaga gcagtcggat gcggaaaaag ctgccgacaa
     8161 gcagcccgtt gccgacaaag ccgacgaggt tgaggaaaag gcggacgagc cggagcggga
     8221 aaagtcggac ggacaggcag tgcgcaagaa agcactgacg gaagagcgtg aacaaaccgt
     8281 cggggaaaaa gcgcagaaga aagatgccga aacggttaaa aaacaagcgg taaaaccatc
     8341 taaagaaaca gagaaaaaag cttcaaaaga agagaaaaag gcggagaagg aaaaagttgc
     8401 acccaaaccg accccggaac aaatcctcaa cagcggcagc atcgaaaaag cgcgcagtgc
     8461 cgctgccaaa gaagtgcaga aaatgaaaac gcccgacaag gcggaagcaa cgcattatct
     8521 gcaaatgggc gcgtatgccg accgccggag cgcggaagga cagcgtgcca aactggcaat
     8581 cttgggcata tcttccaagg tggtcggtta tcaggcggga cataaaacgc tttaccgggt
     8641 gcaaagcggc aatatgtctg ccgatgcggt gaaaaaaatg caggacgagt tgaaaaaaca
     8701 tgaagtcgcc agcctgatcc gttctatcga aagtaaataa ttatgaagct caaacatctg
     8761 ttgccgctgc tgctgtcggc agcgttgtcc gcgcaggcat atgccctgac ggaaggggaa
     8821 gactatcttg tgttggataa acccattcct caagaacagt cgggtaaaat tgaggttttg
     8881 gaatttttcg gctatttctg cgtacattgc catcatttcg atcctttgtt attgaaactg
     8941 ggcaaggcat tgccgtctga tgcctatttg aggacggagc acgtggtctg gcagcctgaa
     9001 atgctcggtc tggccaggat ggcggctgcc gtcaatttgt cgggtttgaa atatcaggca
     9061 aaccctgccg tgtttaaagc agtttacgaa caaaaaatcc gcttggaaaa cagggctgtt
     9121 gccggaaaat gggctttgtc tcaaaaaggc tttgacggca aaaaactgat gcgcgcctat
     9181 gattcccccg aagctgccgc cgccgcatta aaaatgcaga aactgacgga acaataccgc
     9241 atcgacagca cgccgaccgt tattgtcggc ggaaaatacc gcgttatctt caataacggc
     9301 tttgacggcg gcgttcatac gattaaagaa ttggttgcca aagtcaggga agaacgcaag
     9361 cgtcagaccc ctgctgtaca gaaatagccg aactcccgta tccgaaagaa gcgcaagcaa
     9421 tggattttct gattgtcctg aaagccctga tgatgggctt ggtagaaggt tttaccgaat
     9481 ttttaccgat ttccagcacc ggacatttga ttgtgttcgg caatctgatt ggttttcaca
     9541 gcaatcacaa ggtttttgaa attgccatcc agctcggtgc ggttttggcg gtagtgtttg
     9601 aataccggca acgtttcagc aatgtgttgc acggcttggg aaaagaccgg aaagccaacc
     9661 gcttcgtcct taatcttgcc attgctttta tacctgccgc cgtgatgggg ctgttgttcg
     9721 gcaaacaaat caaagagtat ctgtttaacc ccttgagtgt tgcagtcatg ctggttttgg
     9781 gcggtttttt tattttgtgg gtggagaaac gccaaagccg agcagagcct aaaattgccg
     9841 atgttgatgc attgcgtccg attgatgcct tgatgatcgg cgttgcccaa gtgtttgcac
     9901 tggttccggg tacgtcccgt tcgggcagta cgattatggg cgggatgctt tggggcatcg
     9961 aacggaaaac tgcgacagaa ttctcgtttt tcttggctgt gccgatgatg gttgccgcaa
    10021 cggcttatga tgtcctgaaa cattaccgat ttttcaccct gcatgatgtc ggtttgattc
    10081 tgataggctt tattgctgcc tttgtttcag gcttggtagc ggtaaaagcg ttgctgaggt
    10141 ttgtttccaa gaaaaattat attccttttg cctattaccg cattgttttt ggtattgcca
    10201 tcattatatt gtggctgtca ggctggataa gttgggaatg aaaccataaa cccgacctga
    10261 agacattatt cgggtcgggt ttgtctggcg ggctgatata gtgaattaac aaaaatcagg
    10321 acaaggcgac gaagccgcag atagtacggc aaggcgagcc aacgctgtac cggtttaaat
    10381 ttaattcact ataaaatcag gacaggcggg gcgataggtt taaagtcgat tgcctgtttt
    10441 gaaggcagtg gtttattctt tatttgctgg caatcaggca ataaaaaagc acataccttt
    10501 ttacggtctg tgctttttta tctggtggag gtaagcggaa tcgaaccgct gacctcttgc
    10561 atgccatgca agcgctctac caactgagct atacccccga aaatttggtg gcgaatcagg
    10621 gactcgaacc ccggacacaa ggattatgat tcctctgctc taaccgactg agctaattcg
    10681 ccgtttcgtg aagacgctat tatatgtttt tctgtttttt tgacaagccg tattttttaa
    10741 ttttgaatta gttgactgtt tttaaatgtt aaaaagttta tgtcgtctga agcggattca
    10801 ggcggcatga gggttagagt ttgtggcaga tgtcgccgaa gcggaatcct gcccagtcga
    10861 cgccgatatt ttttccgaat gcgatgactt taaacagttc gcccatttca tgctggtcaa
    10921 tcagtttctg aacggcagca gcttcacgga tataggctgc cgaatccgtt ttccccgtct
    10981 gtgccaatag ctcggtaatg cccaggttca ataagaaatg ggattgggga aggtaaccta
    11041 tcaaatctaa tccggcatcc gtaccggctt gggcaatgtc ggtaaagttg acatgcgcgg
    11101 tcaggtcggc caacccgatg aagtcaaaag gattgtggat aacgtgatgt cggtagtgtc
    11161 cgatcagagt accttgattg cgttgagggt ggtaatactg cgctgcatca aaaccgtagt
    11221 cgatgaatat catacccccg cgttcaagtc ttgaggcaag ggtgcggata aaggcatatt
    11281 gttgcggatg tagttcgctg gtgtagggat aatctgtttg aggaaaatag agggaagcca
    11341 aggcagatag ctgtaagtcg tgcagcggtc gtgccgaata ggtaaaacgg tcattatcta
    11401 ggcaaacgcc gacatgctcg aatgagccgc cttcattttt acggacgatt tcgacaggca
    11461 tggcatcgag tacttcgttg ccgatgatga tgccgtcaaa cgcttcggga agtgcggtca
    11521 agtggacaac tttttgagat gcttccggtg cgcgggcttg aatcaggttt ttctgacgtg
    11581 ctgccagctc cggcgatatt tcaataatat agtaacggct gatgccgtcc gaaatgctgc
    11641 ccaacaaatc ggcggcaagc tgtccggttc ccgcgccgaa ttcatagata ttgcccgccg
    11701 tttgggatag aagttcttga agttggcgtg ccagtgtctg tgcaaacaga gaggtgaggg
    11761 tcggtgcagt aataaaatcc ccggtattgc cgattttatg gctgccgccg gtgtagtagc
    11821 cgtattgcgg agcgtataaa accaattcca taaaacgtga aaatggaatc cagttgccgt
    11881 gtttgccgat tttttcggca atgagggttt gcagtttgag cgagaattgc cgtgcttcgg
    11941 gagaggggag ggggaggggc atgataagtg ttagcttgtg taaatttatt ggatttcccg
    12001 acatattaca cgttggtacg ggtgctgtca tggctttatt ttaatactat atattgtgtt
    12061 tatattatta aattaatcat atatagttgt ttattggttc gattattctg taccgcaccc
    12121 gccgtgccgt tgtcgtcatt ttttatctta ttgtttttaa aaggaataaa aatttcagat
    12181 atgttaatga gttttcatgc cctgatttga ccgagtgttt aaaatttctt atagtgtcga
    12241 ttggtgggga attgtggggc aaagtgtctc ttttaccctt gtgattttga tttcggcttg
    12301 ggacatgtca tgttcggcgg cgcacacgaa ttaagcatcg acagtaaggg gcggttggct
    12361 gttcctgcca aattccgtga cattctgtcg cgcctctata cgcctgccgt agtggtaacg
    12421 ctcgagtcga aacacaagct gttgatgtac cctgttgcgg agtgggaaaa ggttgcggcg
    12481 caacttttaa acttaaaagt ggcggataac cctgttttgc ggcggtttca aaatcttttg
    12541 ctgcataacg cggaaatttt ggaatgggac agcgccggcc gggtgctgct tcctgccgga
    12601 ctgaggaaaa gggtggattt cgaccgtgaa gtcgttttgg tcggtcgtgc caaccgtttg
    12661 gagctttggg gtcgcgagca gtgggaggct gagatggttc aggctttgga tgacgatcct
    12721 gacgaacttg ccttccagtt gggtcagacg gatttgcaat tgtgagtgga gcagaaagtt
    12781 accggcatat cacggtcttg ctgaatgagg cggtggatgc gcttgccgtg cgcgaagacg
    12841 gtgtctatgt ggacggtacg ttcggcaggg gagggcattc ccggctgatt ttgtcgcgtt
    12901 tgggcgatgc ggggcggttg attgttttcg acaaagaccc tcaggcgatt gctgtggcag
    12961 aagagctggc gcgttcggac aaacgggtcg gtgtcgtgca tggcggtttt gcttcgtttc
    13021 agacggcatt ggacggtttg ggtatcggca aggtggacgg tgcgctgttt gatttgggga
    13081 tttcgtcccc gcaaatcgat gacggcagcc gcggtttcag cttccgtttc gatgcccctt
    13141 tggatatgcg tatggatacg acgcgcggta tgtctgccgc agagtggata gcggttgcgt
    13201 cggaacagga tttgcacgag gtaatcaaga attatggtga agagcggttt agccgccaga
    13261 ttgcgcgcgc cattgttgcg caacgggcgg aaagtccaat cgatacaacc cgcaagctgg
    13321 cgcagatcgt ggcacaaaac gtccgtactc gcgagcgggg gcaggatcct gcgacgcgca
    13381 ccttccaggc ggtccgcatc tttattaacc gcgagcttga agaagtaggg gcagtattgc
    13441 cgcaggtcat gtgtcgtctg aaagagggcg gacgtttggc ggtcattgct ttccattcgt
    13501 tggaagaccg cattgtgaag cagtttgtca aaaaatattc gcaacacgcg cccctgccgc
    13561 gctgggcggc ggtcagggaa gcggatttgc ccgagccgcc cctgaaaatc gtgggcaggg
    13621 cattaaagcc gggtgaggcg gaaattgccg ccaatccgag ggcgagaagt gcggttttgc
    13681 gtgtggcgga gcggactgcc ggttcgatac cggaacaatc acagagaaaa acgtctgaat
    13741 ggcaatgaac aaattgaatt tccttctgct gcttgcggtg tgcgtttccg ctttttccgt
    13801 tgtgatgcag caaaaccagt acaggctcaa cttcacagct ttggacaagg cgaaaaaaca
    13861 ggaaatcgcc ttggagcagg attatgcgca aatgaggctg caacaggcgc gtttggcgaa
    13921 ccacgaagcg atcagggcgg cggcagaaaa acaaaacctc catccgccgg tttcgggcaa
    13981 tacctttatg gtggcgcatc aaagatagaa gcagcctgtg tgccggaatc ggattcctgc
    14041 gtcaggataa taataacgag aagtaaaaat gttgattaag agcgaatata agcctcggat
    14101 gctgcccaaa gaagagcagg tcaaaaagcc gatgaccagt aacggacgga tcagcttcgt
    14161 cctgatggca atagcggtct tgtttgccgg tctgattgct cgcggactgt atctgcagac
    14221 ggtaacgtat aactttttga aagaacaggg cgacaaccgg attgtgcgga ctcaaacatt
    14281 gccggctaca cgcggtacgg tttcggaccg gaacggtgcg gttttggcgt tgagtgcgcc
    14341 gacggagtcc ctgtttgccg tgcctaaaga gatgaaggaa atgccgtctg ccgcacaatt
    14401 ggaacgcctg tccgagcttg tcgatgtgcc ggttgatgtt ttgaggaaca agctcgaaca
    14461 gaaaggcaag tcgtttatct ggattaagcg gcagctcgat cccaaggttg ccgaagaggt
    14521 caaagccttg ggtttggaaa actttgtatt tgaaaaagaa ttaaaacgcc attacccgat
    14581 gggcaacctg tttgcacacg tcatcggatt taccgatatt gacggcaaag gtcaggaagg
    14641 tttggaactt tcgcttgaag acagcctgca tggcgaagac ggcgcggaag tcgttttgcg
    14701 ggaccggcag ggcaatattg tggacagctt ggactccccg cgcaataaag ccccgaaaaa
    14761 cggcaaagac atcatccttt ccctcgatca gaggattcag accttggcct atgaagagtt
    14821 gaacaaggcg gtcgaatacc atcaggcaaa agccggaacg gtggtggttt tggatgcccg
    14881 cacgggggaa atcctcgcct tggccaatac gcccgcctac gatcccaaca ggcccggccg
    14941 ggcagacagc gaacagcggc gcaaccgtgc cgtaaccgat atgatcgaac ccggttcggc
    15001 aatcaaaccg tttgtgattg cgaaagcatt ggatgcgggc aaaaccgatt tgaacgaacg
    15061 gctgaatacg cagccttata aaatcggacc gtctcccgtg cgcgataccc atgtttaccc
    15121 ctctttggat gtgcgcggca tcatgcagaa atcgtccaac gtcggcacaa gcaaactgtc
    15181 tgcgcgtttc ggtgccgaag aaatgtatga cttctatcat gagttgggca tcggtgtgcg
    15241 tatgcactcg ggctttccgg gcgaaactgc aggtttgttg agaaattggc gcaggtggcg
    15301 gcctattgaa caggcgacga tgtctttcgg ttacggcctg caattgagcc tgctgcaatt
    15361 ggcgcgcgcc tataccgcac tgacgcacga cggcgttttg ctgccggtca gctttgaaaa
    15421 acaggcggtt gcgccgcaag gcaaacgcat attcaaagaa tcgaccgcgc gcgaggtacg
    15481 caatctgatg gtttccgtga ccgagccggg cggcaccggt acggcgggtg cggtggacgg
    15541 tttcgatgtc ggcgcgaaaa ccggcacggc gcgcaagttc gtcaacgggc gttatgccga
    15601 caacaaacac atcgctacct ttatcggttt tgcccccgcc aaaaaccccc gtgtgattgt
    15661 ggcggtaacc attgacgaac cgactgccca cggttattac ggcggcgtag tggcagggcc
    15721 gcccttcaaa aaaattatgg gcggcagcct gaacatcttg ggcatttccc cgaccaagcc
    15781 cctgaccgcc gcagccgtca aaacaccgtc ttaatccgag tatcaacgag attgttttat
    15841 gttcagcaag ttaacccctt tggctgaaac cggcatcccg accctgtcgt gtgcaaacgc
    15901 ggcagggcgt ttgttgcatt cagacagccg ccaaatcaaa caaggcgata ttttcgttgc
    15961 ctgtccgggc gaatatgccg acggacgcag ttatatcccc gccgccgttg ccaacggcgc
    16021 ggcttttgtt ttttgggacg acgacggcaa atttgcgtgg aatcccgaat ggaaagtccc
    16081 caatcaaggc atcaaagatt tgaaacaccg tgccggcata ttggcggcgc aagtttacgg
    16141 caacgtttca gacggtctca aattctgggg cgtaaccgga accaacggca aaacctccat
    16201 cacgcaatgg ctggcgcaag ctgccgattt gttgggcgaa aaaaccgcca ttgtcggcac
    16261 ggtcggcaac ggcttttggg gtgcattgga agaaaccacg cataccacac ccgcccccgt
    16321 cgatgtccaa accctgctct accgtttccg tcaacaaggc gcaacagtcg ccgcgatgga
    16381 agtctccagc cacgggcttg accagtcgcg cgtcaacggc gtgtcattcc gcagcgcaat
    16441 ctttaccaac ctcacccgcg accacctcga ctaccacggc acgatggaag cctacggtgc
    16501 catcaagtcg cgcctgtttt actggcacgg cttgaaacac gcagtcatca acgtggatga
    16561 cgaatacggc gcggaactcg taggtcgtct gaaaaaagac tgtcccgatt tggccgttta
    16621 tagctacggc ttcagcgaac acgccgacat ccgcattatc gatttcaccg cctcttcaga
    16681 cggcatagca gctgtattcc aaaccccgtg gggcgaaggg aaatgccgca cgcgcctgct
    16741 cggacggttc aacgcgcaaa acctcgccgc ctgcatcgcc ttgctgtgcg ccaacggcta
    16801 tccgcttgat aatgtattgg atgtgctggc aaaaatccgt cccgcttcag ggcgcatgga
    16861 ctgcatcatg aacagcggca aacctttggt cgttgtcgat tatgcccata cgcccgacgc
    16921 attggaaaaa gcactcgcca ccttgcagga aatcaaaccg cagggtgcgg ctttgtggtg
    16981 cgtattcggt tgcggcggca accgcgatcg cggcaaacgc ccgctgatgg gcgcggcagc
    17041 cgtacagggc gcggataaag tcgtcgtcac cagcgacaat ccgcgtttgg aaaatccgca
    17101 cgacatcatc aacgacatcc tgcctgccgt tcccgcgccc gaatgcgtcg aagccgaccg
    17161 tgccgccgcc atccgttatg cggttgaaca agccgccgca aacgacatca tcctgattgc
    17221 cggcaaaggg catgaaaact atcaggatgt acaaggcgtg aagcaccgtt tttccgatct
    17281 tgaaatcgtc ggacaggctt tgttaactcg taaataatgg gatattcgga cggcatcgta
    17341 tgaaacaatc cgcccgaata aaaaatatgg atcagacatt aaaaaataca ttgggcattt
    17401 gcgcgctttt agccttttgt tttggcgcgg ccatcgcatc aggttatcac ttggaatatg
    17461 aatacggcta ccgttattct gccgtgggtg ctttggcttc ggttgtattt ttattattat
    17521 tggcacgcgg tttcccgcgc gtttcttcag ttgttttact gatttacgtc ggcacaaccg
    17581 ccctatattt gccggtcggc tggttgtatg gtgcgccgtc ttatcagata gtcggttcga
    17641 tattggaaag caatcctgcc gaggcgcgtg aatttgtcgg caatcttccc gggtcgcttt
    17701 attttgtgca ggcattattt ttcatttttg gcttgacagt ttggaaatat tgtgtatcgg
    17761 ggggggtatt tgctgacgta aaaaactata aacgccgcag caaaatatgg ctgactatat
    17821 tattgacttt gattttgtcc tgcgcggtga tggataaaat cgccagcgat aaagatttgc
    17881 gagaacctga tgccggcctg ttgttgaata ttttcgacct gtattacgat ttggcttccg
    17941 cgccggcaca atatgtcgcc aagcgcgccc acattttgga agcagcaaaa aaagcgtcaa
    18001 catggcatat ccgtcatgtt gcgcccaagt ataaaaatta tgttgtggtt atcggtgaga
    18061 gcgcgcgttc ggattatatg aatgtttacg gtttcccatt gcccgatacg ccttttttga
    18121 gtcagaccaa agggctgttg ataaacggtt accaatcgac cgcccacgcg acgaatcttt
    18181 cgctgccgca gactttgggg ctgccgggag aaccgaacaa taacatcgtc agcttggcga
    18241 agcaggcggg ttttcggacg gcgtggctgt ctaatcaagg aatgttgggg cattttgcca
    18301 acgaaatttc cacctatgcc ctacgcagcg attatccgtg gtttacccaa aggggtgatt
    18361 atggcaaaag cgcggggttg agcgaccgcc ttttgttgcc ggcgttcaaa cgggttttga
    18421 taggaaatgc aggcacgaag cctcggctga ttgtgatgca cctgatgggt tcgcacagtg
    18481 atttttgcac acgtttggat aaggatgcgc ggcggtttca gtatcaaact gaaaaaatat
    18541 cctgctatgt ttccaccatc gcgcaaaccg ataaattttt agaagataca gttaagatat
    18601 tgaatgaaaa taaagaaagc tggtctttgg tttacttttc cgaccacggt ttgatgcatg
    18661 tcggtaaagg cggcgagcga acgttgacac atggtgcgtg gaagcgtcaa agctacggcg
    18721 tgccgctggt taaaatttcg tccgatgaca cgcggcgcga aatgattaaa gtgaggcgca
    18781 gcgcgtttaa ttttttacgc ggattcggca gttggacggg tatcgaaacc gacgagttgc
    18841 ccgatgacgg ctatgatttt tgggggaatg ttcccgatgt gcagggcgaa ggcaataacc
    18901 ttgcctttat cgacggactg cccgacgacc ccgcgccgtg gtatgcggga aaaggcaaat
    18961 cgactaaaaa tacgtctaaa aaatgatacg tacagaaaaa atgccgaatg agaatgggaa
    19021 aataatctgt gttttaccac agcaaaacag gcgataaaaa aatcagccgc taccgatgtg
    19081 tccgccgccc gaatattaac gaaagtaaat atgaaaccac tggacctaaa tttcatctgc
    19141 caagccctca agcttccgat gccgtctgaa agcaaacccg tgtcgcgcat cgtaaccgac
    19201 agccgcgaca tccgcgcggg cgatgtgttt ttcgcattgg cgggcgggcg gtttgatgcg
    19261 catgattttg ttgaagacgt attggctgct ggtgcggcgg cggttgtggt ttcgcgcgaa
    19321 gattgcgttg caatggatgg cgcgttgaaa gtcgatgaca cgcttaccgc gttgcaaatg
    19381 atggcgaagg cgtggcgtga aaacgtggat ccgtttgtgt tcggcattac cggttcgggc
    19441 ggcaagacga cggtgaagga gatgctggct gcggtattgc gccgccgttt cggcgataat
    19501 gccgttttgg cgacggcagg caacttcaac aaccacatcg gattgccgtt gactttgttg
    19561 aaattaaacg aaaaacaccg ctatgccgtg attgaaatgg gtatgaacca ttttggcgaa
    19621 ctggcggttt tgacacaaat cgccaaaccc gatgccgcat tggtcaacaa cgccatgcgc
    19681 gcccatgtcg gctgcggttt cgacggagtg ggcgatattg ccaaagcgaa aagcgagatt
    19741 tatcaaggct tatgttcaga cggcatggca ctgattcctc aagaagatgc caatatggct
    19801 gtcttcaaaa cggcaacgct taatttgaat acgcgcactt tcggcatcga tagcggcgat
    19861 gtccacgcgg aaaatatcgt gctgaaaccg ttgtcgtgcg aatttgattt ggtgtgcggc
    19921 gacgaacgcg ccgccgtggt gctgcctgtt cccggccgcc acaatgtcca caacgccgcc
    19981 gctgccgccg cgctgtcttt ggctgcaggt ttgagtttga acgatgtggc ggaaggtttg
    20041 aaaggcttca gcaatatcaa aggccgtctg aacgtcaaat ccggaatcaa gggcgcaacc
    20101 ctgattgacg atacttataa tgcgaaccct gacagcatga aagctgcgat tgacgtgttg
    20161 gcgcgtatgc ctgcgccgcg tattttcgtg atgggcgata tgggcgaact gggtgaggac
    20221 gaagccgccg ccatgcacgc cgaagtcggc gcgtatgctc gcgaccaagg catcgaagcg
    20281 gcttattttg tcggcgacaa cagcgtcgaa gcggcggaaa aatttggcgc ggacggtttg
    20341 tggttcgccg ccaaagaccc gttgattcaa gtgttgcgcc acgatttgcc cgaacgcgcc
    20401 accgtgttgg tgaaaggttc gcgctttatg cagatggaag aagtggtcga ggcattggag
    20461 gataagtgaa aatgaaaagt cgacgttttt ttaaagcctt attgttgatt gccgcgctgg
    20521 tcggcgcgtt ttatgccgga atgcagacgc aggcgtatct ttatgaagat ttatgtttag
    20581 acttgggtgg cggcaaaaat ccggggagtt acccgatttg cgtgattgag aaagtccctg
    20641 cacgttaatc tgcaaaagcc gtccgaaacc ttgccgggcg gcaagccaac ctcaaacggg
    20701 cgcaggcccg atgtatagtg gattaacaaa aatcaggaca aggcgacgaa gccgcagaca
    20761 gtacaaatag tacggaaccg attcacttgg tgcttcagca ccttagagaa tcgttctctt
    20821 tgagctaagg cgaggcaacg ccgtactggt ttttgttaat ccactataac gacaaaacaa
    20881 aaaaaggaag ccccatgttt ttatggctcg cacatttcag caactggtta accggtctga
    20941 atatttttca atacaccaca ttccgcgccg tcatggcggc gttgaccgcc ttggcgtttt
    21001 ccctgatgtt cggcccgtgg acgatacgca ggctgaccgc gctcaaatgc gggcaggcag
    21061 tgcgtaccga cggtccgcaa acccacctcg tcaaaaacgg cacgccgacg atgggcggtt
    21121 cgctgattct gaccgccatt accgtgtcca ccctgttgtg gggcaactgg gcaaacccgt
    21181 atatctggat tctcttgggc gtattgctcg ccacgggcgc actcggtttt tacgacgact
    21241 ggcgcaaagt cgtctataaa gaccccaacg gcgtgtccgc caaattcaaa atggtgtggc
    21301 agtcaagcgt tgccattatc gccagtttgg cattgtttta ccttgccgcc aattccgcca
    21361 acaatatttt gattgtcccg ttcttcaaac aaatcgccct gccgctgggc gtggtcggct
    21421 ttttggtgtt gtcttacctg accatcgtcg gcacatccaa tgccgtcaac ctcaccgacg
    21481 gcttggacgg ccttgcgacc ttccccgtcg tcctcgttgc cgccggcctc gccatcttcg
    21541 cctatgccag cggccactca caatttgccc aatacctgca attaccttac gttgccggcg
    21601 caaacgaagt ggtgattttc tgtaccgcca tgtgcggcgc gtgcctcggt ttcttgtggt
    21661 ttaacgccta tcccgcgcaa gtctttatgg gcgatgtcgg tgcattggca ttgggtgccg
    21721 cgctcggtac cgtcgccgtc atcgtccgcc aagagtttgt cctcgtcatt atgggcggat
    21781 tatttgtcgt agaagccgta tccgttatgc ttcaggttgg ctggtataag aaaaccaaaa
    21841 aacgcatctt cctgatggcg cccatccatc accactacga acaaaaaggc tggaaagaaa
    21901 cccaagtcgt cgtccgcttt tggattatta ccatcgtctt ggtattgatc ggtttgagta
    21961 ccctcaaaat ccgctgaacc tatgccgtct gaacaccttt cagacggcat ttgaacgcgc
    22021 aataaacctg cggcggcaat ctgtcccgtc ctatcgttaa cggtggctga aaaaccgccc
    22081 cacaccgaaa taggagagaa aacatgaaac agacagtcaa atggcttgcc gccgccctga
    22141 ttgccttggg cttgaaccaa gcggtgtggg cggatgacgt atcggatttt cgggaaaact
    22201 tgcaggcggc agagcaggga gatgctgatg cccaaaacaa tttgggcgcg atgtatgccg
    22261 aaggacaagg cgtgcgccaa gatgataccg aagcggtcag atggtttcgg caggcggcgg
    22321 atcaggggtt agcacaagcc caatttaatt tgggcgcaat gtattacaaa gggcacggcg
    22381 tgcgccaaga ccgcgccctt gcacaagaat ggcttggcaa ggcgtgtcaa aacggaaacc
    22441 aagacggctg cgacaatgac caacgcctga aagcgggtta ttgaacagct cgcaatgccg
    22501 tctgaaagcg gcttgagcag gagtagacat ccccctgccc aatatgattt gttttaggac
    22561 aaaccaaaat gactttccaa aacaaaaaaa tcctcgtcgc cggacttggc ggcacgggta
    22621 tttccatgat tgcctacctg cgcaaaaacg gcgcggaggt tgctgcgtat gatgcggagc
    22681 tgaagccgga acgcgtgtcg caaatcggta agatgtttga cgggctggtg ttttacacgg
    22741 gccgtctgaa agatgcgctg gacaacggtt tcgatattct ggcgctcagt cccggcatca
    22801 gcgagcggca gccggatatc gaggcgttca agcaaaacgg cggacgcgtg ttgggcgaca
    22861 tcgaattgct ggcggacatt gtgaaccgcc ggggcgacaa ggtaattgcg attaccggca
    22921 gcaacggcaa aaccacggta acgagcctgg tcggctatct ctgtatcaag tgcgggctgg
    22981 ataccgttat cgcgggcaat atcggcacgc cggttttgga ggcggaatgg cagcgcgaag
    23041 gcaaaaaggc ggacgtgtgg gtgttggagc tttccagctt ccaactggaa aacaccgaaa
    23101 gcctgcgccc gactgcggcg acggtgctga acatttccga agaccatctc gaccgctacg
    23161 acgacttgct cgactacgcg cataccaaag ccaagatttt ccgtggcgat ggcgtgcagg
    23221 ttttgaatgc ggacgatgcg ttctgtcgtg cgatgaagcg cgccgggcgc gaggtgaaat
    23281 ggttttcgtt ggaatacgaa gccgattttt ggttggaacg tgagacaggt cgcctgaaac
    23341 aaggcaatga agatttgatt gccacgcaag atattccgct gcaaggcttg cacaacgcca
    23401 ctaacgtgat ggctgccgtt gccttgtgcg aagccgtcgg tttgccgcgc gaagcattgc
    23461 tcgaacacgt caaaaccttt caaggcctgc cgcaccgcgt ggaaaaaatc ggcgagaaaa
    23521 atggcgtggt gttcatcgac gacagcaaag gcacgaacgt cggtgcgacc gccgccgcga
    23581 ttgccggttt gcaaaatccg ctcttcgtga ttttaggcgg catgggcaaa gggcaggact
    23641 tcacgcctct gcgcgacgcg cttgccggca aggcaaaagg cgtgttcctg atcggcgttg
    23701 atgcgccgca aatccgccgc gatttggacg gctgcggtct gaatatgacc gactgcgcca
    23761 ctttggaaga agccgttcag acggcatatg cccaagccga agcgtgcgat atcgtgctgc
    23821 tcagcccggc ttgtgcgagt tttgatatgt ttaaaggcta cgcgcaccgt tcggaagtgt
    23881 ttatcgaagc gtttaaggct ttgtgatgcc gtctgaaatg caaacgccgt cattgttggg
    23941 cggcaagtaa agatttagaa taccgatttg ggatgtatcg tatgttcgga cggcattgtc
    24001 tgccgtctga aatttttgcc ctttgcggca ggtgcaaaca gactggcagg tggttttttt
    24061 gaagatttcg gaagtattgg taaaagtggg cgacagtgtc cacactctgc tgctcgacag
    24121 gccgattgtg cgcgacggca ggaaattcga cgcgccgctt ttgtggatgg tggtgctgat
    24181 gacggcgttc agcctgctga tgatttattc ggcttctgtg tatttggcat caaaagaagg
    24241 cggcgatcag tttttctatt tgaccagaca ggcggggttc gtcgttgccg gcttgatagc
    24301 gagcggtttg ttatggtttc tttgcaggat gaggacatgg cggcggcttg tgccgtggat
    24361 ttttgcccta tccggcctgt tgctggtagt cgtattgatt gccgggcgcg aaatcaatgg
    24421 cgcgacccgt tggatacctt tgggtccgtt gaatttccag ccgaccgagc tgttcaagct
    24481 ggcggtcatc ctttatttgg caagcctgtt cacgcgccgt gaagaagtgt tgcgcagcat
    24541 ggaaagtttg ggttggcagt cgatttggcg ggggacggcc aatctgatca tgtccgccac
    24601 caatccgcag gcacgtcgtg aaacattaga aatgtacggc cgtttccggg cgatcatcct
    24661 gccgattatg ctggtggcgt tcggtttggt gctgataatg gtacagccgg atttcggttc
    24721 gtttgtcgtc attaccgtca ttgccgttgg aatgctgttt ttggcaggat tgccgtggaa
    24781 atattttttc gtcctggtag gcagcgtctt gggcgggatg gtgctgatga ttaccgccgc
    24841 tccctaccgt gtgcagcggg tagtggcatt tttggacccg tggaaagacc cgcagggtgc
    24901 cggctaccag cttacccact ctctgatggc aatcgggcgc ggagagtggt tcggtatggg
    24961 tttgggtgcg agtttgagca aacgcggctt tctgccggaa gcgcataccg attttatttt
    25021 tgccatcatc gccgaagaat tcggtttctt cggtatgtgt gtgctgatat tctgttacgg
    25081 ctggctggtg gtgcgggcgt tttccatcgg caagcagtcg cgcgatttgg gtttgacttt
    25141 caacgcctat atcgcttcgg gtatcggcat ttggatcggt atccaaagtt tcttcaatat
    25201 cggtgtgaac atcggtgctt tgccgaccaa aggtctgacg ctgccgttga tgtcctatgg
    25261 cggttcgtca gtctttttca tgctgatcag catgatgctg ctgttgcgta tagattatga
    25321 aaaccgccgg aaaatgcgcg gttatcgggt ggagtaaatc atgggcggta aaacctttat
    25381 gctgatggcg ggcggaacgg gcggacatat tttccccgcg ctggcggtgg cggattcatt
    25441 gcgcgcgcgc ggccatcatg tgatttggct gggcagcaag gattcgatgg aagagcgtat
    25501 cgtgccgcaa tacggcatac gcttggaaac gctggcgatt aaaggcgtgc gcggcaacgg
    25561 catcaaacgc aaactgatgc tgccgtttac tttgtatcaa accgtccgcg aagcgcagcg
    25621 gattatccgc aaacaccgtg tcgagtgcgt catcggcttc ggcggcttcg ttaccttccc
    25681 cggcggtttg gcggcgaagc tattaggcgt gccgattgtg attcacgagc aaaacgccgt
    25741 ggcaggtttg tccaaccgcc acctgtcgcg ctgggcgaag cgggtgttgt acgcttttcc
    25801 gaaagcgttc agccacgaag gcggcttggt cggcaacccc gtccgcgccg atattagcaa
    25861 cctgcccgtg cctgccgaac gcttccaagg gcgtgaaggc cgtctgaaaa ttttggtggt
    25921 cggcggcagt ttgggcgcgg acgttttgaa caaaaccgta ccgcaggcat tggctttgct
    25981 gcccgacaat gcgcgtccgc agatgtacca ccaatcggga cggggcaagc tgggcagctt
    26041 gcaggcggat tacgacgcgc tgggcgtgaa agccgaatgt gtggaattta ttaccgacat
    26101 ggtgtccgcc taccgcgatg ccgatttggt gatttgccgt gccggcgcgc tgacgattgc
    26161 cgagttgacg gcggcgggat tgggtgcgtt gttagtgccg tatcctcacg ccgttgatga
    26221 ccatcaaacc gccaacgcac gttttatggt gcaggcggag gcgggattgc tgttgccgca
    26281 aacccagttg acggcggaaa aactcgccga aatcctcggc agcctgaacc gcgaaaaatg
    26341 tctcaaatgg gcagaaaacg cccgtacttt ggcactgccg cacagtgcgg acgacgttgc
    26401 cgaagccgcg attgcgtgtg cggcgtaaac tgccgaacca tgccgtctga aaagccgttc
    26461 agacggcatg gatgtttttt atttcaatcc gctatatatt tgtcagaaaa ctatggcgcg
    26521 caaacggtca gccctttaaa ataacgcctt tacgcactaa aaaccaaccg gaacgcaaca
    26581 ttatgatgaa aaatcgagtt accaacatcc attttgtcgg tatcggcggc gtcggcatga
    26641 gcggcatcgc cgaagtcttg cacaatttgg gttttaaagt ttccggttcg gatcaggcgc
    26701 gaaatgccgc taccgagcat ttgggcagcc tgggcattca agtttatccc ggccataccg
    26761 cagaacacgt taacggtgcg gatgtcgtcg ttacctctac cgccgtcaaa aaagaaaatc
    26821 ccgaagttgt cgctgcgttg gagcagcaaa ttcccgttat tccgcgcgcc ctgatgttgg
    26881 cggagttgat gcgcttccgt gacggcatcg ccattgccgg cacgcacggc aaaaccacga
    26941 ccaccagcct gaccgcctcc atcctcggcg cggcaggact tgacccgact ttcgttatcg
    27001 gcggcaaact caacgccgca ggcaccaacg cccgcttggg caaaggcgaa tacatcgttg
    27061 ccgaagccga cgagtcggat gcatcctttc tgcacctgac accgattatg tccgtcgtta
    27121 ccaatatcga cgaagaccat atggatacct acgggcacag tgttgagaag ctgcatcagg
    27181 cgtttatcga tttcatccac cgtatgccct tctacggcaa agcctttttg tgtattgaca
    27241 gcgaacacgt ccgcgcgatt ttgcccaaag tgagcaaacc ttatgctact tacggtttgg
    27301 acgataccgc cgacatctac gccaccgaca tcgaaaacgt cggcgcgcaa atgaaattca
    27361 ccgtccatgt tcaaatgaaa ggacatgagc aggggtcgtt tgaagtcgtg ctgaatatgc
    27421 ccggcagaca caacgtgctg aacgcattgg cagccatcgg cgtggcgctg gaagtcggcg
    27481 catcggttga agcgatccaa aaaggcttgc tcggctttga aggcgtcggc cgccgcttcc
    27541 aaaaatacgg cgacatcaag ttgccaaacg gcgggaccgc gctcttggtg gacgactacg
    27601 gacaccaccc cgtcgaaatg gcggcgaccc ttgccgccgc acgcggcgcg tatccggaaa
    27661 aacgtttggt actcgccttc cagccgcacc gctatacccg cacgcgcgat ttgtttgaag
    27721 actttaccaa agtcctcaat accgttgacg cgctggtgct gaccgaagtt tatgccgccg
    27781 gtgaagagcc gattgccgcc gccgattccc gcgctcttgc ccgcgccatc cgcgtgttgg
    27841 gcaaactcga gccgatttac tgcgaaaacg ttgccgatct gcccgaaatg ctgttgaacg
    27901 ttttgcagga cggcgacatc gtgttgaata tgggcgcggg aagcatcaac cgcgttcccg
    27961 ccgcgctact ggaattgtcg aaacagattt gaggcacacc ctcctgacag acggaacatc
    28021 atataaaggt cgtctgaaac cgcaaatcag gtttcagacg acctctggca acaagcataa
    28081 agcaatcagg aaagaacaaa aaacaatgca gaattttggc aaagtggccg tattgatggg
    28141 cggtttttcc agcgaacgag aaatctcgct ggacagcggc accgccattt tgaacgcttt
    28201 aaaaagcaaa ggcatagacg catacgcctt cgatcccaag gaaaccccat tgtctgaatt
    28261 gaaggcacaa ggttttcaga cggcattcaa catccttcac ggtacttacg gcgaagacgg
    28321 ggcggttcaa ggcgcgttgg aactgttggg cattccctat accggcagcg gtgtcgccgc
    28381 ctccgccatc ggcatggaca aataccgctg caaactgatt tggcaggcat tggggctgcc
    28441 cgttcccgag ttcgccgtcc tgcacgacga cactgatttc gatgccgtcg aagaaaaatt
    28501 gggcctgccg atgtttgtga aaccggcggc cgaaggcagc agcgtcggtg tggtaaaagt
    28561 caaagaaaaa ggccgtctga aaagcgttta cgaagaattg aaacaccttc agggcgaaat
    28621 cattgccgaa cggtttatcg gcggcggcga atattcctgc cccgtcctga acggcaaagg
    28681 cctgcccggc atacacatca tccccgcgac cgagttttac gactacgaag ccaagtacaa
    28741 ccgcgacgac accatttatc aatgtccttc ggaagatctg accgaagccg aagaaagcct
    28801 gatgcgcgaa ctggcggttc gcggcgcgca ggcaatcggt gcggaaggct gcgtgcgcgt
    28861 cgatttcctc aaagataccg acggcaaact ctatctgttg gaaatcaaca ccctgcccgg
    28921 tatgacgagc catagtttag taccgaaatc cgctgccgtt acgggcgtgg gttttgccga
    28981 tttatgtatt gaaattttga agaccgcaca tgtgggataa tgccgaagcg atggaacggc
    29041 tgacgcgctg gctgcttgtc atgatggcga tgctgcttgc tgcgtccggg ctggtttggt
    29101 tttacaattc gaatcatctg cccgtcaagc aggtgtcgct gaagggcaac ctggtttatt
    29161 ccgataagaa agcattgggc agtttggcga aagaatacat ccatgggaat attttgagga
    29221 cggacatcaa tggcgcacag gaggcctacc gccggtatcc gtggattgcg tcggtcatgg
    29281 tgcgccgccg ttttcccgac acggttgagg tcgtcctgac cgagcgcaag ccggtcgcgc
    29341 gttggggcga ccatgccttg gtggacggcg aaggcaatgt ttttgaagcc cgcttggaca
    29401 gacccggaat gccggtattc agaggcgcgg aaggaacgtc tgccgaaatg ctccgccgtt
    29461 atgacgaatt ttcgactgtt ttggcaaaac agggtttggg catcaaagag atgacctata
    29521 cggcacgttc ggcgtggatt gtcgttttgg acaacggcat caccgtcagg ctcggaaggg
    29581 aaaacgagat gaaacgcctc cggcttttta ccgaagcgtg gcagcatctg ttgcgtaaaa
    29641 ataaaaatcg gttatcctat gtggatatga ggtataagga cggattttca gtccgctatg
    29701 cttccgacgg tttacccgaa aaagaatccg aagaatagtg ggaacaggta tcggacagat
    29761 tacggccgtg ccgtctgaaa cggtgcgacg caaatttcaa tcagttttaa gagcagacga
    29821 acaatggaac agcagcaaag atacatcagc gtactggata tcggtacgtc taaagtcctc
    29881 gcactgatcg gggaagttca agatgacgac aaaatcaaca tcgtcggttt ggggcaggct
    29941 ccttcacggg gcttgcgcgc gggcatggta accaatatcg atgccaccgt ccaagccatc
    30001 aggcaggcgg tcaatgatgc cgagctgatg gcggatacca aaattactca cgttaccaca
    30061 ggtatcgcag gcaaccacat ccgcagtctc aattcgcaag gtgtggttaa aattaaagat
    30121 ggggaagtca cgcaggcaga catcgatcgc gccattgaaa cggcaaaggc aatcaatatc
    30181 ccgcccgatc aaaaaattct cgatgccgtg gttcaagact acattattga cacccaactt
    30241 ggcgtgaggg agcccatcgg tatgagcggt gtgcgtctgg atacgcgggt gcacatcatt
    30301 accggtgcaa gtacggcagt gcagaatgtc caaaaatgta tcgagcggtg cggtttgaaa
    30361 agcgatcaga tcatgcttca gccgttggca agcgggcagg cggtgctgac tgaagatgaa
    30421 aaagacctcg gcgtatgcgt catcgacatt ggtggcggaa cgaccgatat tgccgtttat
    30481 atgaacggtg ccatccgcca tacgtccgtc attccggccg gtggtaatct gattaccaaa
    30541 gatttgtcca aatcgttgag aacacctctc gatgccgccg agtacattaa aatccattat
    30601 ggcgtggcat catgcgatac ggaaggcttg ggtgagatga ttgaagttcc gggcgtgggt
    30661 gaccggacat cgcgtcaggt ttccagtaag gttttggcag caatcatcag cgcacgtatt
    30721 caggagattt ttggcgtagt gctgggcgag ctgcaaaaat cgggtttccc caaagaagtg
    30781 ctgaatgcgg gtatcgttct gaccggcggt gtgtccatga tgaccgggat tgtggaattt
    30841 gccgaaaaaa tcttcgattt gcctgtacgc accggtgcgc cccaagaaat gggcggtttg
    30901 tccgaccgcg tccgcacacc gcgcttttct accgccatcg ggctgcttca tgcagcatgc
    30961 aagctggaag gaaacttgcc gcagccggaa aacggtgcag tgcaagagag ggaagggggc
    31021 ggcggtttgt tggcaagatt gaaacggtgg attgaaaaca gcttctgaac aggtggattg
    31081 ccgtttgaca ggtgagaagt attttgccag cagcaagata cttcttatat aatgaataat
    31141 aatttattta aaccgtcctc tgaatggggc gagcaggagt ttttgaatgg aatttgttta
    31201 cgacgtggca gaatcggcag tcagccctgc ggtgattaaa gtaatcggct tgggcggcgg
    31261 cggttgcaat gcaatcaata acatggttgc caacaatgtg cgcggtgtgg agtttatcag
    31321 tgccaatacg gatgcgcagt ctttggcaaa aaaccatgcg gcgaagagaa tccagttggg
    31381 tacgaatctg acacgcggtt tgggcgcggg cgcgaatccc gatatcggcc gtgcggcagc
    31441 ccaggaagac cgggaagcca ttgaagaagc cattcgcggt gcgaatatgc tgtttatcac
    31501 gaccggtatg ggcggcggta ccggtaccgg ttccgcgccg gttgttgctg agattgccaa
    31561 gtctttgggc attctgaccg ttgccgtggt tacccgaccg ttcgcatatg aaggtaagcg
    31621 cgtccatgtc gcacaggcag ggttggaaca gttgaaagaa cacgtcgatt cgctgatcat
    31681 catcccgaac gacaaactga tgactgcatt gggtgaagac gtaacgatgc gcgaagcctt
    31741 ccgtgccgcc gacaatgtat tgcgcgatgc ggtcgcaggc atttccgaag tggtaacttg
    31801 cccgagcgaa atcatcaacc tcgactttgc cgacgtgaaa accgtgatga gcaaccgcgg
    31861 tatcgctatg atgggttcgg gttatgccca aggtatcgac cgtgcgcgta tggcgaccga
    31921 ccaggccatt tccagtccgc tgctggacga tgtaaccttg gacggagcgc gcggtgtgct
    31981 ggtcaatatt acgactgctc cgggttgctt gaaaatgtcc gagttgtccg aagtcatgaa
    32041 aatcgtcaac caaagcgcgc atcccgattt ggaatgcaaa ttcggtgcgg ctgaagacga
    32101 gaccatgagc gaagatgcca tccggattac cattatcgct accggtctga aagaaaaagg
    32161 cgcggtcgat tttgttccgg caagggaggt agaagcggtt gctccgtcca aacaggagca
    32221 aagccacaat gtcgaaggta tgatccgcac caatcgcggt atccgcacga tgaaccttac
    32281 cgctgcggat ttcgacaatc agtccgtact tgacgacttt gaaatccctg cgattttgcg
    32341 tcgtcaacac aattcagaca aataatgtgc tgtttgcccg taaacctgct gcctcccgaa
    32401 tcggtttgtc cggtttggga ggtatgtttt tcaagatgtt gcaatttcgt acggtttgcg
    32461 gtcggcggat tcagattttt ccacttgata cagactttca gatatggaca cttcaaaaca
    32521 aacactgttg gacgggattt ttaagctgaa ggcaaacggt acgacggtgc gtaccgagtt
    32581 gatggcgggt ttgacaactt ttttgacgat gtgctacatc gttatcgtca accctctgat
    32641 tttgggcgag accggcatgg atatgggggc ggtattcgtc gctacctgta tcgcgtctgc
    32701 catcggctgt tttgttatgg gttttgtcgg caactatccg attgcactcg caccggggat
    32761 ggggctgaat gcctatttca cctttgccgt cgttaagggt atgggcgtgc cttggcaggt
    32821 tgcgttgggt gcggtgttca tctccggtct gatttttatc ctgttcagct tttttaaagt
    32881 cagggaaatg ctggtcaacg cactgcctat gggtttgaaa atgtcgattg ctgccggtat
    32941 cggtttgttt ttggcactga tttccctgaa aggcgcaggc attatcgttg ccaatccggc
    33001 aaccttggtc ggtttgggcg atattcatca gccgtccgcg ttgttggcat tgttcggttt
    33061 tgctatggtg gtcgtattgg gacatttccg cgttcaaggc gcaatcatca tcaccatctt
    33121 gaccattacc gtcattgcca gcctgatggg tttgaatgaa tttcacggca tcatcggcga
    33181 agtaccgagc attgcgccga cttttatgca gatggatttt gaaggcctgt ttaccgtcag
    33241 catggtcagt gtgattttcg tcttcttctt ggtcgatcta tttgacagta ccggaacgct
    33301 ggtcggcata tcccaccgtg ccgggctgct ggtggacggt aagctgcccc gcctgaaacg
    33361 cgcactgctt gcagactcta ccgccattgt ggcaggtgcg gctttgggta cttcttccac
    33421 cacgccttat gtggaaagcg cggcgggcgt atcggcaggc ggacggaccg gcctgacggc
    33481 ggttaccgtc ggcgtattga tgctcgcctg cctgatgttt tcacctttgg cgaaaagtgt
    33541 tcccgctttt gccaccgcgc ccgccctgct ttatgtcggc acgcagatgc tccgcagtgc
    33601 gagggatatt gattgggacg atatgacgga agccgcaccc gcattcctga ccattgtctt
    33661 catgccgttt acctattcga ttgcagacgg catcgccttc ggcttcatca gctatgccgt
    33721 ggttaaactt ttatgccgcc gcaccaaaga cgttccgcct atggtatgga ttgttgccgt
    33781 attgtgggca ctgaaattct ggtatttggg ctgattgatt cgatattaaa aatgccgtct
    33841 gaaaggtttt cagacggcat tttgtttgcc gatatattta atttttatta aattatataa
    33901 aaatcaaata tataataaaa tacatcggat tgcttaaaaa taatacattg tttttatgta
    33961 taaaatattt tataagtttt caggattttg attatcgaaa atttttcttg atttcctgac
    34021 aattttattg aaacaaataa ttcaaaatta atctagttta atcatggaat taaaataaaa
    34081 tattaaaatt atgtaatgag tctccttaaa aatgtttgac attttcagtc ttgtgtttta
    34141 gattatcgaa aaataaaact acataacact acaaaggaac attactatga aaccaattca
    34201 gatgttttcc ccttttctga ataatcccct tgttttcttc ttgtctgcgg ttttgccgca
    34261 taattccgaa cggtctgctg tttttctttg attcgtttta aatatcaata agataatttt
    34321 tcccatatat ttttaatgat tggattggga tgcccgacgc gtcggatggc tgtgttttgc
    34381 cgtccgaatg tgatggaagc ctgtccatac tgaaaaaaag tctataaagg agaaatatga
    34441 tgagtcaaca ctctgccgga gcacgtttcc gccaagccgt gaaagaatcg aatccgcttg
    34501 ccgtcgccgg ttgcgtcaat gcttattttg cacgattggc cacccaaagc ggtttcaaag
    34561 ccatctatct gtccggcggc ggcgtggcag cctgttcttg cggtatccct gatttgggca
    34621 ttaccacaat ggaagatgtg ctgatcgacg cacgacgcat tacggacaac gtggatacgc
    34681 ctctgctggt ggacatcgat gtgggttggg gcggtgcatt caatattgcc cgtaccattc
    34741 gcaactttga acgcgccggt gttgcagcgg ttcacatcga agatcaggta gcgcaaaaac
    34801 gctgcggcca ccgtccgaac aaagccattg tatctaaaga tgaaatggtc gaccgtatca
    34861 aagctgccgt agatgcgcgc gttgatgaga acttcgtgat tatggcgcgt accgatgcgc
    34921 tggcggtaga aggtttggat gccgctatcg aacgcgccca agcttgtgtc gaagccggtg
    34981 cggacatgat tttccctgaa gccatgaccg atttgaacat gtaccgccaa tttgcagatg
    35041 cggtgaaagt gcccgtgttg gcgaacatta ccgagtttgg ttccactccg ctttataccc
    35101 aaagcgagct ggctgaaaac ggcgtgtcgc tggtgctgta tccgctgtca tcgttccgtg
    35161 cagcaagcaa agccgctctg aatgtttacg aagcgattat gcgcgatggc actcaggcgg
    35221 cggtggtgga cagtatgcaa acccgtgccg agctgtacga gcatctgaac tatcatgcct
    35281 tcgagcaaaa actggataaa ttgtttcaaa aatgatttac cgctttcaga ctgcctttca
    35341 acaaatccgc atcggtcgtc tgaaaacccg aaacccataa aaacacaaag gagaaatacc
    35401 atgactgaaa ctactcaaac cccgaccctc aaacctaaaa aatccgttgc gctttctggc
    35461 gttgcggccg gtaataccgc tttgtgtacc gttggccgta ccggcaacga tttgagctat
    35521 cgcggttacg acattctgga tttggcacaa aaatgcgagt ttgaagaagt cgcccacctg
    35581 ctgattcacg gccatctgcc caacaaattc gagctggccg cttataaaac caagctcaaa
    35641 tccatgcgcg gcctgcctat ccgtgtgatt aaagttttgg aaagcctgcc tgcacatacc
    35701 catccgatgg acgtaatgcg taccggcgta tccatgctgg gctgcgttca tcctgaacgt
    35761 gaaagccatc cggaaagtga agcgcgcgac atcgccgaca aactgatcgc cagcctcggc
    35821 agcatcctct tgtactggta tcaatattcg cacaacggca aacgcattga ggttgaaagc
    35881 gacgaagaga ccatcggcgg tcatttcctg caactgttgc acggcaaacg cccaagcgaa
    35941 tcacacatca aagccatgca cgtttcactg attctgtatg ccgaacacga gttcaacgct
    36001 tctaccttta ccgcccgcgt gatcgccggt acaggctctg atatgtactc cagcattacc
    36061 ggagcaatcg gcgcgttgaa aggtccgaaa cacggcggcg cgaacgaagt ggcttacgat
    36121 attcaaaaac gctaccgcaa tgccgacgaa gctgaagccg acatccgcga acgcatcggc
    36181 cgcaaagaaa tcgtgatcgg tttcggtcat ccggtgtaca ccatttccga ccctcgcaac
    36241 gttgtcatta aagaagtggc acgcggtttg agcaaagaaa ccggcgatat gcgcctcttt
    36301 gacattgccg aacgtttgga aagcgtgatg tgggaagaga aaaaaatgtt cccgaatctg
    36361 gactggttct ctgccgtttc ctaccaaaaa ttgggcgtac cgaccgctat gttcacaccg
    36421 ctgttcgtaa tttcccgtac aaccggttgg agcgcacacg ttcttgagca acgcaaagac
    36481 ggcaaaatca tccgtccgag cgcaaactac acaggccctg aagatttggc gtttgtggag
    36541 attgaagaac gataattgaa gaatgcaata gcagtttgtt ctttaatttc ggtatgcaaa
    36601 gctgaggatt tcagacgacc ttgcctgatt ggaaaggttg tctgaaataa gtttaaaaat
    36661 ttaacctaat agaagaagat aatcctgtat tggtgcaagt aacaggataa gaaacatgga
    36721 agatttatac ataatactcg ctttgggttt ggttgcgatg attgccggat ttatcgatgc
    36781 gattgcgggt gggggtggtt tgattacgct gcctgcactc ttgttggcag gtattcctcc
    36841 cgtgtcggca attgccacca acaagctgca agcagccgct gctacgtttt cggctacggt
    36901 ttcttttgca cgcaaaggtt tgattgattg gaagaaaggt ctcccgattg cggcagcatc
    36961 gtttgcaggc ggcgtggtcg gtgcattatc ggtcagcttg gtttccaaag atattctgct
    37021 ggcggtcgtg ccggttttgt tgatatttgt cgcgctgtat tttgtgtttt cgcccaagct
    37081 cgacggcagt aaggaaggca aagccagaat gtcttttttt ctgttcggtc tgacggttgc
    37141 accacttttg ggtttttacg acggtgtgtt cggaccgggt gtcggctcgt tttttctgat
    37201 tgcctttatt gttttgctcg gctgcaagct gttgaacgcg atgtcttaca ccaaattggc
    37261 gaacgttgcc tgcaatcttg gttcgctatc ggtattcctg ctgcacggtt cgattatttt
    37321 cccgattgcg gcaacgatgg cggtcggtgc gtttgtcggt gcgaatttag gtgcgagatt
    37381 tgccgtccgc ttcggttcga agctgattaa gccgctgctg attgtcatca gcatttcgat
    37441 ggctgtgaaa ttgttgacag acgagagaaa tccgctgtat cagatgatta tttcgatgtt
    37501 ttaaaccctt tcagacgacc ccttcaaaac gtcggctgaa acctcaaacc acaagaaaaa
    37561 cagatcccca ggagaaccga catggctgcc aaccaacgtt accgcaaacc gctgcccggt
    37621 acggatttgg aatactacga cgcgcgtgcg gcgtgtgagg acatcaagcc cggctcttac
    37681 gacaagctgc cttacacgag ccgcattttg gcggagaatt tggtcaaccg cgcggacaaa
    37741 gtcgatttgc cgacgctgca aagctggctg ggtcagctga ttgagggaaa acaggaaatc
    37801 gactttcctt ggtatccggc gcgggtggtg tgccacgata ttctggggca gaccgcgttg
    37861 gtggatttgg caggtctgcg cgatgcgatt gccgaaaaag gcggcgatcc tgccaaagtg
    37921 aatccggtgg tgcaaaccca gctcattgtc gaccactctt tggccgttga atgcggcggt
    37981 tacgatcctg atgccttccg caaaaaccgc gaaatcgaag acagacgtaa cgaagaccgt
    38041 ttccacttta tcaactggac aaaaaccgca tttgaaaatg tggacgtgat tccggcgggc
    38101 aacggcatca tgcaccaaat caatctggaa aaaatgtcgc cggttgttca agttaaaaac
    38161 ggcgtggcgt tccccgatac ctgcgtcggc acggattcgc acacgccgca cgtcgatgcg
    38221 ctgggcgtga tttccgtggg tgtgggcgga ttggaagcgg aaaccgtaat gctgggacgc
    38281 gcgtccatga tgcgcctgcc cgatattgtc ggtgtggagc tgaccggcaa acggcaggcg
    38341 ggcattacgg cgacggatat tgtgttggcg ctgaccgagt ttctgcgcaa agagcgcgtg
    38401 gtcggggcgt ttgtcgaatt cttcggcgag ggcgcgagaa gcctgtctat cggcgaccgc
    38461 gcgaccattt ccaacatgac gccggagttc ggcgcgactg ccgcgatgtt cgctattgat
    38521 gagcaaacca ttgattattt gaaactgacc ggacgcgacg acgcgcaggt gaaattggtg
    38581 gaaacctacg ccaaaaccgc aggcttatgg gcagatgcct tgaaaaccgc cgtttatcct
    38641 cgcgttttga aatttgattt gagcagcgta acgcgcaata tggcaggtcc aagtaacccg
    38701 catgcccgtt ttgcgaccgc cgatttggcg gcgaaagggc tggcgaagcc ttacgaagag
    38761 ccttcggacg gacaaatgcc cgacggcgcg gtcatcatcg ccgcgattac cagttgcacc
    38821 aacacttcca acccgcgcaa cgtcgttgcc gccgcgctgt tggcacgcaa tgccaaccgc
    38881 ctcggcttga aacgcaaacc ttgggtgaaa tcttcatttg ccccgggttc aaaagtagcc
    38941 gaaatctatt tgaaagaagc aggcctgctg cccgaaatgg aaaaactcgg cttcggtatc
    39001 gtcgccttcg cctgcaccac ctgtaacggc atgagtggcg cgctggatcc gaaaacccag
    39061 aaagaaatca tcgaccgcga tttgtacgcc accgccgtac tgtcaggcaa ccgcaacttc
    39121 gacggccgtg tccatccgta tgcgaaacag gctttcctcg cttcgcctcc gttggtcgtt
    39181 gcctacgcgc tggcaggcag tatccgtttc gatattgaaa acgacgtact cggcgttgca
    39241 gacggcaagg aaatccgcct gaaagacatt tggcctgccg atgaagaaat cgatgccgtc
    39301 gttgccgaat atgtgaaacc gcagcagttc cgcgatgtgt atgtaccgat gttcgacacc
    39361 ggcacagcgc aaaaagcacc tagtccgctg tacgactggc gtccgatgtc cacctatatc
    39421 cgccgcccac cttactggga aggcgcactg gcaggggaac gcacattaag aggtatgcgt
    39481 ccgctggcga ttttgcccga caacatcacc accgaccacc tctcgccgtc caatgcgatt
    39541 ttggccgtca gtgccgcagg cgagtatttg gcgaaaatgg gtttgcctga agaagacttc
    39601 aactcttacg caacccaccg cggcgaccac ttgaccgccc aacgcgctac cttcgccaat
    39661 ccgaaactgt ttaacgaaat ggtgaaaaac gaagacggca gcgtgcgcca aggctcgttc
    39721 gcccgcgtcg aacccgaagg cgaaaccatg cgcatgtggg aagccatcga aacctatatg
    39781 aaccgcaaac agccgctcat catcattgcc ggtgcggact atggtcaagg ctcaagccgc
    39841 gactgggctg caaaaggcgt acgcctcgcc ggcgtagaag cgattgttgc cgaaggcttc
    39901 gagcgtatcc accgcaccaa ccttatcggc atgggcgtgt tgccgctgca gttcaaaccc
    39961 gacaccaacc gccataccct gcaactggac ggtacggaaa cctacgacgt ggtcggcgaa
    40021 cgcacaccgc gctgcgacct gaccctcgtg attcaccgta aaaacggaga aaccgtcgaa
    40081 gttcccgtta cctgccgcct cgatactgca gaagaagtat tggtatatga agccggcggc
    40141 gtgttgcaac ggtttgcaca ggattttttg gaagggaacg cggcttagag gtcgtctgaa
    40201 aagcaagacg tagcgtgggt cgggttcaac attttgctca ttcacgtaat tctcgatatg
    40261 gcaggcatct actgtaaatc gtcattcccg cgcaggcggg aatccagaaa gtggaattga
    40321 ggaaacctta tttatccgat gagtttctgt gcggacaaat ttggattccc gcctgcgcgg
    40381 gaatgacggg gtttaataat ctgccgtatc acaacacagt agccgtagat tgtggcgaac
    40441 cccgacagtt tgcggaatca aacggctttg tcggagtggc agcctaatgt acttctggaa
    40501 agtgggtgta gcgtgggctt tgcccgcgaa ataaaggctg aattgacatg gtatagagga
    40561 ttaacaaaaa tcgggacaag gcggcgaagc cgcagacagt acagatagta cggaaccgat
    40621 tcacttggtg cttcagcacc ttagagaatc gttctctttg agctaaggcg agccaacgct
    40681 gtactggttt ttgttaatcc actataaatt taatccacta tactgtaaat cgtcattccc
    40741 gcgcaggcgg gaatccagaa agtggaattg aggaaacctt tttatccgat gagtttctgt
    40801 gcggataaat ctggattccc gcctgcgcgg gaatgacggg gtttaataat ctgccgtatc
    40861 acaacacagt agccgtagat tggggcgaac cccgacagtt tgcggaatca aacggctttg
    40921 gtcggagtgg cagcctaatc cactataaaa atcgtgggca gagcccacgc tacataagga
    40981 gaatctagaa atgccgcaaa ttaaaattcc cgccgtttac taccgtggcg gtacatcaaa
    41041 aggcgtgttt ttcaaacgtt ccgacctgcc cgaggcggcg cgggaagcgg gaagcgcacg
    41101 cgacaaaatc ctcttgcgcg tactcggcag cccggatccc tacggcaagc agatagacgg
    41161 tttgggcaac gccagctcgt ccaccagcaa ggcggtgatt ttggacaagt ccgaacgcgc
    41221 cgatcacgat gtcgattacc ttttcgggca agtttccatc gacaaacctt ttgtcgattg
    41281 gagtggcaac tgcggcaacc tcaccgccgc cgtgggcgca tttgccatcg agcaaggctt
    41341 ggtcgataaa ggcaagattc cttcagacgg catctgcaca gtcaaaatct ggcagaaaaa
    41401 catcggcaaa accattattg cccatgtacc gatgcaaaac ggcgcagttt tggaaacagg
    41461 cgattttgag ctcgacggcg taacgttccc ggcagccgaa gtacaaatcg aatttcttga
    41521 tccagccgac ggcgaaggca gtatgttccc aaccggcaat ttggtcgatg aaattgatgt
    41581 gccgaatata ggccgtttga aagccacgct catcaacgcg ggcattccga ccgttttcct
    41641 gaatgccgcc gacttgggct acacgggcaa agagttgcaa gacgacatca acaacgatgc
    41701 cgcagctttg gaaaaattcg agaaaatccg cgcttacggt gcgctgaaaa tgggtctaat
    41761 cagcgacgta tccgaagctg ccgcccgcgc gcacacgccg aaagtcgcct tcgtcgcgcc
    41821 cgccgccgat tacaccgcct ccagtggcaa aaccgtgaat gccgccgaca tcgatttgct
    41881 ggtacgcgcc ctgagcatgg gcaaattgca ccacgcgatg atgggtaccg cctctgttgc
    41941 cattgcgacc gccgccgccg tgcccggtac gctggtcaac cttgccgcag gcggcggaac
    42001 gcgtaaagaa gtgcgcttcg ggcatccttc cggcacattg cgcgtcggtg cagccgccga
    42061 atgtcaggac ggacaatgga cggccaccaa agcggttatg agccgcagcg cacgcgtgat
    42121 gatggaaggt tgggtcaggg tgccggaaga ttgtttttaa attgacgtag catgggtttg
    42181 cccgcgagcc ataaacaggt cgtctgaaaa acaagtaaac atcaaatcac tgaccattcc
    42241 tttcccttgc cctgtggcgg aaggcggcaa atcacaagga agaacacgga aaccccgata
    42301 aaagacagct tcccgtatta ccgtcattcc cgcgcaggcg ggaatctaga cctgtcaata
    42361 tggaggattg gtaggggaaa acaggtttcg tgagttctac attctggatt cccgccacag
    42421 cctgtcctcg cgtaggcggg gacggaataa cgatagaaaa tgcggcatac gctttgccca
    42481 aagaggccgt ctgaaacacc ttgcgcctga tgtctgcctt tttcagacga ccccacacca
    42541 aaaaaacaac cacaaactac aaggagaaac atcatgtccg accaactcat cctcgttctg
    42601 aactgcggca gttcatcgct caaaggcgcc gttatcgacc gcaaaagcgg cagcatcgtc
    42661 ctaagctgcc tcggcgaacg cctgaccacg cccgaagccg tcattacgtt cagcaaagac
    42721 ggcaacaaac gccaagttcc cctgagcggc cgaaattgcc acgccggcgc ggtgggtatg
    42781 cttttgaacg aactggaaaa acacggtctg cacgaccgca tcaaagccat cggccaccgc
    42841 atcgcccacg gcggcgaaaa atacagcgag tctgttttga tcgaccaggc cgtaatggac
    42901 gaactcaatg cctgcattcc gcttgcgccg ctgcacaacc ccgccaacat cagcggcatc
    42961 ctcgccgcgc aggaacattt ccccggtctg cccaatgtcg gcgtgatgga tacttcgttc
    43021 caccaaacca tgccggagcg tgcctacact tatgccgtgc cgcgcgagtt gcgtaaaaaa
    43081 tacgctttcc gccgctacgg tttccacggc accagtatgc gttacgttgc ccctgaagcc
    43141 gcacgcatct tgggcaaacc tctggaagac atccgcatga ttattgccca cttaggcaac
    43201 ggcgcatcca ttaccgccat caaaaacggc aaatccgtcg ataccagtat gggtttcacg
    43261 ccgatcgaag gtttggtaat gggtacacgt tgcggcgaca tcgatccggg cgtatacagc
    43321 tatctgactt cccacgccgg gatggatgtt gcccaagtgg atgaaatgct gaacaaaaaa
    43381 tcaggtttgc tcggtatttc cgaactttcc aacgactgcc gcaccctcga aatcgccgcc
    43441 gacgaaggcc acgaaggcgc gcgcctcgcc ctcgaagtca tgacctaccg cctcgccaaa
    43501 tacatcgctt cgatggctgt ggcctgcggc ggcgttgacg cactcgtgtt caccggcggt
    43561 attggcgaaa actcacgtaa tatccgagct aaaaccgttt cctatcttga tttcttgggt
    43621 ctgcacatcg acactaaagc caatatggac aaacgctacg gcaattcggg tattatcagc
    43681 ccgaccgatt cttctccggc tgttttggtt gtcccgacca atgaagaact gatgattgcc
    43741 tgcgacactg ccgaacttgt cggcatcttg tagccaaaaa agggacgagt ccgcacaatg
    43801 ccgtctgaaa ccccaaacgc ccgattaggc tgatgaggat tttagacggc attgttcatt
    43861 tttttgttat cttgcatttt tgtgcggacg gtggaatttc atcctgtaaa cataaatatt
    43921 tgtcggaaaa cagaaaccct ccgccgccat ttctacgaaa gcaggaaacc agcaacgcaa
    43981 agcgacaggg atttgttgga aatgaccgaa accgaacgaa ccggattccc gcctgcgcgg
    44041 gaatgacggg attttctgtt tttgtggaaa tgacgggatt ttgaatttcg ggcgtacaat
    44101 acggaaaaca tgacgataag gacacaaacc atggcacagt ttttcgccgt tcatcccgac
    44161 aatccccaag aacgcctcat caagcaggcg gttgaaatcg tcaatcaagg cggcgtggtg
    44221 gtttatccga ccgattcgtg ttacgccttg ggttgcaaac tcggcgataa ggcggcgatg
    44281 gaacgcatac tctccatccg caaaatcgat ttgaaacacc acctgaccct gatgtgcgcc
    44341 gatttgagcg agttgggcac gtacgccaaa attgacaacg tacagtttcg tcagcttaaa
    44401 gccgccacgc ccgggcctta tacctttatc ttgcaggcga cgaaggaagt gccggcgcgc
    44461 acgctgcacc cgaaacgcaa aaccatcggg ctgcgtattc ccgataatgc cattgcacaa
    44521 gccctgctgg gggaattggg cgagccgctt ttaagctgca ccctgatgct gcccgaagac
    44581 ggcgaaccat tgaccgatcc ttatgaaatc cgcgagcgtt tggaacacgc cgtcgatttg
    44641 gtgattgacg gcggctggtg cggaaccgag ccgaccaccg tcgtcgatat gaccgacggc
    44701 acggaattgg tgcgccaagg ttgcggcgat acggcggtgt tcggtttgta gggaaaccga
    44761 tgccgtctga agcatcggct gttcagacgg cattgcgcgc cttgccggcg gcagtccgaa
    44821 atgccggcgc gtatcgcgct cggtcggaat atccgtttga aacggcattt tgatgcatta
    44881 ctgcaccgca atcggaattc tcggttcgta gagcaggtcg taggtcggct tgttgagcag
    44941 gtcttggagc gtgaaaccgt ccagatacgt gaaaaatgac ttcatcgcgc cgccgagtat
    45001 gcccgtcagc cggcaggacg gtgtaatcag gcattcgttg ttctcgccca tgcactcgac
    45061 cagctgcatc ggttcgaggt ggcggacaac cgagccgatg ttgatgcggt cgggcggtgc
    45121 ggcaagccgc agaccgccgc cttttccgcg cacactgtgg aggaagccgc ctttgaccag
    45181 cgcggtaacg accttcatca gatggctttt ggaaatgccg taggttacgg cgatggtact
    45241 gatgttgacc agcgcatcgt cgttgatggc agtgtagata aggacgcgca gcccgtagtc
    45301 cgtatgttgt gtcaaataca tgattttctc ggtatggatc gttattctta tcggtacggt
    45361 ttaagtttca cggaaaatac cttaatggtt gaaaccctgt ccgtcggggc ggtagaatgc
    45421 agcctgtctg cggcggtatg ccgtctgaaa catccgcgct accgtttgat aatttgttat
    45481 tgtaactcaa aatcatgaaa ccgttgaaac gacatcccgc ccttatcggg ctttcgcgtg
    45541 accaccacca ttcgctttcc ctgtgcgtgc gtctgttgcg gacgccggaa gaaaggcatc
    45601 gggacgaact cgaaccgcat tttgccgaat tggaaaccca ttttcgcgaa gaagaagcca
    45661 agtttgcccc aatttggcag aatgtcgccc ccgaattgaa acaacgtttc gagaaagacc
    45721 acgcccgact gcggcagatg atggcaagcc ccgaatacgg taacgcggcg tggaataccg
    45781 cttttgccac aaccctgcgc gaccacgcgc gctttgaaga acgcgagctg tttcccgccg
    45841 ccgaaccgtt tttgccggca tgattccgtt ttgcggcaaa tatattaatg ataaacaagg
    45901 aacacacatg aaatttacca agcaccccgt ctgggcaatg gcgttccgcc cgttttattc
    45961 gctggcggct ctgtacggcg cattgtccgt attgctgtgg ggtttcggct acacgggaac
    46021 gcacgagctg tccggtttct attggcacgc gcatgagatg atttggggtt atgccggact
    46081 ggtcgtcgtc gccttcctgc tgaccgccgt cgccacttgg acggggcagc cgcccacgcg
    46141 gggcggcgtt ctggtcggct tgactatctt ttggctggct gcgcggattg ccgcctttat
    46201 cccgggttgg ggtgcgtcgg caagcggcat actcggtacg ctgtttttct ggtacggcgc
    46261 ggtgtgcatg gctttgcccg ttatccgttc acagaatcaa cgcaactatg ttgccgtgtt
    46321 cgcgctgttc gtcttgggcg gcacgcatgc ggcgttccac gtccagctgc acaacggcaa
    46381 cctaggcgga ctcttgagcg gattacagtc gggcttggtg atggtgtcgg gttttatcgg
    46441 tctgattggt acgcggatta tttcgttttt tacgtccaaa cggttgaatg tgccgcagat
    46501 tcccagtccg aaatgggtgg cgcaggcttc gctgtggctg cccatgctga ccgccatgct
    46561 gatggcgcac ggcgtgatgc cttggctgtc ggcggctttc gcgtttgcgg caggcgtgat
    46621 ctttaccgtg caggtgtacc gctggtggta taaacccgtg ttgaaagagc cgatgctgtg
    46681 gattctgttt gccggctatc tgtttaccgg attggggctg attgcggtcg gcgcgtctta
    46741 tttcaaaccc gctttcctca atctgggtgt gcatctgatc ggggtcggcg gtatcggcgt
    46801 gctgactttg ggcatgatgg cgcgtaccgc gctcggtcat acgggcaatc cgatttatcc
    46861 gccgcccaaa gccgttcccg ttgcgttttg gctgatgatg gcggcaaccg ccgtccgtat
    46921 ggttgccgta ttttcttccg gcactgccta cacgcacagc atacgcacct cttcggtttt
    46981 gtttgcactc gcgcttttgg tgtatgcgtg gaagtatatt ccttggctga ttcgtccgcg
    47041 ttcggacggc aggcccggtt gagacaaacc gccgcagatt tcgggtctgg gcggtttgct
    47101 tttcagacgg cagggcggtc agttgccgtc cagccagcgg tcgcgtgtgg ttttggcttc
    47161 ttcaaaatag cggtacaggg cttcgcggtc gtcggtggtc aggatgtttg ccaaaacgtc
    47221 caactgtttg cccaagcctt gaaccagttg cagcaggctg tctttgttgg caaggcagat
    47281 gtccgcccac acggcgggat gaccggaggc gatgcgggtg aagtcccgaa agcccgtggc
    47341 ggcgaatttc agatattcct gtccgtcggg gtggtcgaga atctggtgga cataggcgaa
    47401 ggcggtcagg tggggcatat gggagacggc ggcgaaaacc gcgtcgtggc gttgcgcgtc
    47461 catcgtataa atttccgccc cgaccgcgcg ccacaggttt tctatcaagg caatgccgtc
    47521 tgaatgttcg ccgccgtgtg gcgtgatgat gagttttctg tggcggaaca gcccgaactg
    47581 cgcggcttgc gcaccgcttc tgtccgaacc ggcaatcggg tgggcggcga tgcagcggtg
    47641 caggcggtcg ggcagacagc ggcggaaggc ttcgatgacc gaagatttgg tgctgccgac
    47701 atcggaaatc caagtgtgtt ccggcaaaac ggggcgcagc gcggtcaaaa tggcgggaac
    47761 ggtggcgacg ggcgtggcaa tcagtaccaa gtccgcaccg ccgatgctgt ccgcgtcgat
    47821 ggcaacggaa gcccggtcaa tcacgccgcg ttccaatgca cgttcgaggt tgtcgcggtc
    47881 ggtgtcgata ccggtaacgg tgcggacgag tccctgcctt ttgaggtcga gaacgaacga
    47941 accgccgatc agccctacac cgatgagggc aatatggttc aaaatgggca tttgtgtaaa
    48001 cggttttcgc aaagtaccgt catggtagcc tatcggcgga atatgccgca aggtcggcag
    48061 gaaaaaggag aagaaatgga caaaatcaga gttgccgccg tgcagatggt gtcgggcgtg
    48121 tcgccggaaa ccaacgtcgc cgccatgaaa cgcctggtcg cacgggcggc ggagcagggt
    48181 gcggattggg tgctgctgcc cgaatattgg gtgctgatgg gcgcaaacga taccgacaaa
    48241 ctcgcgcttg ccgagccttt gggcggcgga cgctttcaga cggcattgag cgaaacggcg
    48301 aaagaatgcg gcgtggtgct gtttggcgga accgtgccgc tgcaaagccc cgaggcgggc
    48361 aaggtcatga atactttatt ggtgtacggg cgcgacggca aacggacggg gctgtaccac
    48421 aaaatgcacc tcttcggctt ttccggtttg ggcgaacgct atgccgaagc cgataccatc
    48481 cgcgcgggcg gggaagtgcc gcacttgtcg gcagaaggcg tgccggtggc ggcaggtatt
    48541 tgttacgatg tccgctttcc cgaatttttc cgccgccagc tgccgtttga cgtattgatg
    48601 ctgcccgctg cgtttacgca cacgacgggc aaggcgcatt gggagctgct gctgcgcgcg
    48661 cgtgccgtcg aaaaccaatg ttacgtcgtg gcggcggcac agggcggttt gcacgaaaac
    48721 ggacggcgca cgttcggaca cagcatgatt gtcgatccgt ggggcgacgt gttggacgta
    48781 ttgcccgaag gcgaaggcgt tgttacggca gacatcgatg ccaaccgcct gaacagcgtc
    48841 cgcaaccgcc tgcccgcctt gaaataccgg gttttggatg ccgtctgaag gttcagacgg
    48901 catcggtgcc ggggaatcag cgggctgtag gatgggcttc agcctgccat ttccatcaat
    48961 cccacatttc taccgttttc atcgaatcca tcgaatccgc ccctttcgac gccccagtcc
    49021 tacgcaactg aaccgtcatt cccacggaag tgggaatcta gaatctcggg gtttcagtca
    49081 tttccgatag attcccgccg cgtcaggggg ctggattccc gcctgcgcgg gaatgacgaa
    49141 tccatccata cggaaacctg cacc
//
LOCUS       DAXISH010000009        40913 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.009, whole genome shotgun sequence.
ACCESSION   DAXISH010000009 DAXISH010000000
VERSION     DAXISH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 40913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40913
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.009"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(323..625)
                     /locus_tag="ACFOV4_000503"
     CDS             complement(323..625)
                     /locus_tag="ACFOV4_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HFC7618583.1"
                     /translation="MQRQSLTNADGEVRELAAEDFALARPIAEALPEDLAQVLFSHQK
                     QLEEKGVMQKRNTGKTPKQLVTIRLSADVVEKFRAGGKGWQTRINEVLRQYVAQLK"
     gene            complement(597..884)
                     /locus_tag="ACFOV4_000504"
     CDS             complement(597..884)
                     /locus_tag="ACFOV4_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HFC7618584.1"
                     /translation="MKIEFDSEKNQRNIEERNLPFESVGQIRWTTAVIVPDVCFDYPE
                     PRYVAAAYLGDTQRLHIVCFTPIKDGIRVISFRKANKREVKKYATSILNKR"
     gene            964..1569
                     /locus_tag="ACFOV4_000505"
     CDS             964..1569
                     /locus_tag="ACFOV4_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618585.1"
                     /translation="MTIYFKNGFYDDTLGSIPEGAVAVRAEEYAALLAGQAQGGQIAA
                     DSDGRPVLTPPRPSEYHEWDGKKWEIGEAAAAARFAEQKTATAFRLAAKADELKNSLL
                     AGYPQVEIDSFYRQEKEALARQADNNAPTPMLAQIAAARGVELDVLIEKVVEKSARLA
                     VAAGAIIGKRQQLEDKLNTIETAPGLDALEKEIEEWTLNIG"
     gene            1548..1844
                     /locus_tag="ACFOV4_000506"
     CDS             1548..1844
                     /locus_tag="ACFOV4_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrD"
                     /protein_id="HFC7618586.1"
                     /translation="MDAKHRLKKYVYHLLVAIDQLFNALTGGAADETLSSRTYRGARL
                     AQKPKTRWKVLYTLINGVFFDRQHCRQAYISELKGRQHDARFNQSRAAGEKGTR"
     gene            1841..2050
                     /locus_tag="ACFOV4_000507"
     CDS             1841..2050
                     /locus_tag="ACFOV4_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618587.1"
                     /translation="MNYFGMVEFLRLMAMVRPPFVFFSGTRSELPTYLDLVAELRLTG
                     WERFAGSQTLTVSSTSTAIQATTTT"
     gene            complement(2220..3302)
                     /locus_tag="ACFOV4_000508"
                     /pseudo
     CDS             complement(2220..3302)
                     /locus_tag="ACFOV4_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003743106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SbmA/BacA-like family transporter"
     gene            complement(3745..4392)
                     /locus_tag="ACFOV4_000509"
     CDS             complement(3745..4392)
                     /locus_tag="ACFOV4_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF799 domain-containing protein"
                     /protein_id="HFC7618588.1"
                     /translation="MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPL
                     NESPDVNGTWGVLASTAAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQ
                     IFGNDAVLYITVTEYGTSYQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSN
                     SGLLGALVSAVVNQIANSLTDRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK"
     gene            complement(4389..4757)
                     /locus_tag="ACFOV4_000510"
     CDS             complement(4389..4757)
                     /locus_tag="ACFOV4_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4810 domain-containing protein"
                     /protein_id="HFC7618589.1"
                     /translation="MNPKTLSRLSLCAAVLALTACGGNGQKSLYYYGGYPDTVYEGLK
                     NDDTSLGKQTEKMEKYFVEAGNKKMNAAPGAHAHLGLLLSRSGDKEGAFRQFEEEKRL
                     FPESGVFMDFLMKTGKGGKR"
     gene            complement(4767..5438)
                     /locus_tag="ACFOV4_000511"
     CDS             complement(4767..5438)
                     /locus_tag="ACFOV4_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsgG/HfaB family protein"
                     /protein_id="HFC7618590.1"
                     /translation="MKTVSTAVVLAAAAVSLTGCATESSRSLEVEKVASYNTQYHGVR
                     TPISVGTFDNRSSFQKGIFSDGEDRLGSQAKTILVTHLQQTNRFNVLNRTNLNALKQE
                     SGISGKAHNLKGADYVVTGDVTEFGRRDVGDHQLFGILGRGKSQIAYAKVALNIVNVN
                     TSEIVYSAQGAGEYALSNREIIGFGGTSGYDATLNGKVLDLAIREAVNSLVQAVDNGA
                     WQPNR"
     gene            complement(5603..6322)
                     /locus_tag="ACFOV4_000512"
     CDS             complement(5603..6322)
                     /locus_tag="ACFOV4_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFC7618591.1"
                     /translation="MATLSDKTILITGASQGLGEQVAKAYAAAGATVILVARHQKKLE
                     KVYDAIVEAGHPEPFAIRFDLMSAEEKEFNQFAATIAEATQGKLDGIVHCAGYFYALS
                     PLDFQTVAEWVNQYRINTVAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGF
                     GASKAALNYLCKVAADEWERFGNLRANVLVPGPINSPQRIKSHPGEAKSERKSYGDVL
                     PAFVWWASTESKGRSGEIVYL"
     gene            complement(6406..7719)
                     /gene="hpnE"
                     /locus_tag="ACFOV4_000513"
     CDS             complement(6406..7719)
                     /gene="hpnE"
                     /locus_tag="ACFOV4_000513"
                     /EC_number="1.17.8.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="HFC7618592.1"
                     /translation="MMNTPHPRPKIAVIGAGWAGLSAAVTLARYADVTLFEAGRQAGG
                     RARALAGNTDGFGFLDNGQHILLGAYRGVLRLMKTIGSDPRAAFLRVPLHWHMHGGLQ
                     FRALPLPAPLHILGGVLLARRVPSAFKGKLLADMSDLQKSARLGQPDTTVAQWLKQRN
                     VPRAAVMQFWQPLVWGALNTPLETASLRVLCNVLSDGVLTKKSGSDYLLPKQDLGAIV
                     AEPALAELQRLGADIRLETRVCRLNPLPDGKVLVNGEAFDAAVPATAPYHAAALLPEG
                     TPEHVQTAYQNLRYHAITTVYLRYAEPVRLPAPLTGLADGTAQWLLCRGRLGLPENEV
                     SAVISVSDRVGAFTNRAWADKVHADLKRILPHLGEPEAVRVITEKRATTAADAPPPDL
                     SWLHRHRIFPAGDYLHPDYPATLEAAVQSGFASAEACLQSLSDAV"
     gene            complement(7749..7955)
                     /locus_tag="ACFOV4_000514"
                     /pseudo
     CDS             complement(7749..7955)
                     /locus_tag="ACFOV4_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224552.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8117..8989)
                     /gene="hpnD"
                     /locus_tag="ACFOV4_000515"
     CDS             complement(8117..8989)
                     /gene="hpnD"
                     /locus_tag="ACFOV4_000515"
                     /EC_number="2.5.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA];
                     GO_process: GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="HFC7618593.1"
                     /translation="MKGLDYCRQKAEESRSSFLSGFRFLTQEKRDAVTVLYAFCRELD
                     DVVDECSNPDVAQATLNWWRGDLDKVFGGAMPEHPVNQALRQVKETFKLPKYELEALI
                     DGMQMDLVQARYGSFEELKLYCHRVAGVVGCLIARILGFSDDQTLEYADKMGLALQLT
                     NIIRDVGEDARRGRIYLPMEEMRRFDVPASVILQCSPTGNFAELMAFQIKRARETYCE
                     AVSLLPAADKKAQKVGLVMAAVYYELLNEIDRDGAQNVLKYKIALPSPRKKRIALKTW
                     LFGFKPRPGTPERA"
     gene            9160..11022
                     /gene="hscA"
                     /locus_tag="ACFOV4_000516"
     CDS             9160..11022
                     /gene="hscA"
                     /locus_tag="ACFOV4_000516"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HFC7618594.1"
                     /translation="MALLQISEPGMSAAPHRHRLAAGIDLGTTNSLVATVRSGSAACL
                     PDAEGRVTLPSVVRYLENGGIEVGKTALSAQKTDPLNTVSSAKRLIGRTLADLHQNTH
                     YLPYRFGGNQRVIELHTRQGVKTPVEVSAEILKTLKSRAEETLGGDLVGVVITVPAYF
                     DDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNASEGTFVVYDLGGGTFDVSVL
                     QLTKGLFEVKATGGNSALGGDDFDHRLFCRLLEQNGLSQLNEQDSQLLLSLVRAAKEQ
                     LTTQTEARIQATLSDGMPIDTSISRAEFHNLTQHLVMKTLEPVTQALKDAGVGKNEVK
                     GVIMVGGSTRMLHVQQAVATFFGQTPLNNLNPDEVVALGAAIQANVLAGNKTDGEWLL
                     LDVTPLSLGLETYGGLAEKIIPRNSTIPTARAQDFTTFKDGQTAMTIHVVQGERELVS
                     DCRSLAKFTLRGIPPMAAGAARIRVTFQIDADGLLSVSAQEQSTGVQAQIEVKPSYGL
                     DDDTITQMLKDSMSNAAEDMAARARAEAVVEAESLTDAVNAALELDSDLLEAEELQQI
                     RQGIADLQGRVKDGKAEDIRAAAAKLGSITDNFAAKRMNRNIQRALTGQSVDNI"
     gene            11098..11745
                     /locus_tag="ACFOV4_000517"
     CDS             11098..11745
                     /locus_tag="ACFOV4_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFC7618595.1"
                     /translation="MEKSGIVYLMKTVIKGVYKIGISDVSNFEGRMRHLENNGYANVA
                     GLERILAVKTDNYKEKENLLHEIFSKSRTELFAVDENLVKRLFLSLRGEIVFPKNETA
                     ESEFEKSVHERRQEGNAGSGRKQLLDLVRRGHREYPYALPRLLAGAASYKPKKSKIRL
                     FKEAYLRKSGTRLTDEIADGIHIYTCFSRADLEKAYSEYLELFKSESDAEGRKPR"
     gene            11781..12542
                     /locus_tag="ACFOV4_000518"
     CDS             11781..12542
                     /locus_tag="ACFOV4_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2314 domain-containing protein"
                     /protein_id="HFC7618596.1"
                     /translation="MMGDSVIYYVEQADEPVNRAGERARKTFKYFWRELFWERRRIIP
                     ALDFAMVKAPFFQDGEDGEICEHMWIDDIYFDGLYIYGVLNNEPGELTNVEQGESICV
                     PVDDISDWMFVCNGIPYGGFTVQAMRGQMTEEERTEHDAAWGIDFGDPGQILLVYEEK
                     EHPENLEEHPMCRNCIDDFRQQLSQNSDFLHEQDEDGYTPLHHEAIAGNALMVQAMLE
                     YGASPASTTSEGYTALDFARLAGWQNVADLLEPRH"
     gene            12598..12939
                     /gene="fdx"
                     /locus_tag="ACFOV4_000519"
     CDS             12598..12939
                     /gene="fdx"
                     /locus_tag="ACFOV4_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009425374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HFC7618597.1"
                     /translation="MPKITVLPHATLCPEGAVIDNAPEGKTVLDVLLDHDIEVDHACE
                     KSCACTTCHVIIRKGFDSLEEPTELEEDLLDQAWGLEADSRLSCQAVVAGEDLIVEIP
                     KYTINHAREEH"
     gene            complement(13226..13813)
                     /locus_tag="ACFOV4_000520"
     CDS             complement(13226..13813)
                     /locus_tag="ACFOV4_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFC7618598.1"
                     /translation="MNNMFAAKLSKLVYTASDHPDSLSEMEEFDRLILLIRKLYQILD
                     GQHILSRVTVCLHHQNRRGLIALDKAAAGCDAAMLRAQRWRIYTQIAERLSGSGGGFT
                     VTAESVSAACPELEGRYLELVRRAAVSFGFTQGWENPAGGQEKTQAVPDAASGHSVRK
                     PIKINIEAKVERYPAYRPTAALKVTRRRFFRLQNR"
     gene            14026..14223
                     /gene="iscX"
                     /locus_tag="ACFOV4_000521"
     CDS             14026..14223
                     /gene="iscX"
                     /locus_tag="ACFOV4_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HFC7618599.1"
                     /translation="MKWTDTRRIAEELYDLHSETIDPRTVRFTQLRDLIMALPEFDDD
                     PARCGERILEAVQQAWIDEAE"
     gene            complement(14291..14692)
                     /locus_tag="ACFOV4_000522"
     CDS             complement(14291..14692)
                     /locus_tag="ACFOV4_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFC7618600.1"
                     /translation="MKDKHDSSAMRLDKWLWAARFFKTRSLAQKHIELGRVQVNGSKV
                     KNSKTIDIGDIIDLTLNSLPYKIKVKGLNHQRRPASEARLLYEEDAKTAALREERKQL
                     DQFSRITSAHPDGRPTKRDRRQLDRLKKGDW"
     gene            14903..15862
                     /locus_tag="ACFOV4_000523"
     CDS             14903..15862
                     /locus_tag="ACFOV4_000523"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HFC7618601.1"
                     /translation="MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKS
                     NDLTKSIFSKLTPAQISQVSRHPQRPYTLDYIEALFTDFEELHGDRHFADDYAIVGGL
                     ARFNGQSVMVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDT
                     PGAYPGIGAEERGQSEAIGKNLYELTRLHVPVLCTVIGEGGSGGALAVAVGDYVNMLQ
                     YSTYSVISPEGCASILWKTAEKAADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDF
                     GQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ"
     gene            15930..17240
                     /gene="tilS"
                     /locus_tag="ACFOV4_000524"
     CDS             15930..17240
                     /gene="tilS"
                     /locus_tag="ACFOV4_000524"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFC7618602.1"
                     /translation="MLTLDAFEQCLKDCFPQGLNGKKTAVALSGGLDSVVLLHLLVRA
                     GKKGGFIPDALHIHHGLSPRADDWADFCQNYCDMLGVGLETVKICVEKNGLGIEAAAR
                     QKRYAAFAEKGFDVLALAHHRDDQIETFMLAVARGGGLRALAAMPAVRPFGEKGIIWR
                     PLLPFSRQDIWDYAQKHGLPNIEDESNSDTAYLRNRFRHRILPELSAQIPHFGRHLLN
                     NVRALQEDLALLDEVVVQDCRWVCGAGYFDTARWLTFSPRRKTHILRHFLKENGIPVP
                     NQNALADIARVLTEAKTGRWNVQGFELHHYAGRLFVFRPEKTDKLRFLKDRQISGNLR
                     EILAGQGFVLKRHPFGLPGHLLEQDGILRTVAASDRLAVGGIHKDVKKILQEKRVLPA
                     LRPFWPVVADKDNRPLALANYGTDFQISVSDGILPVHPDFPVLF"
     gene            17291..18076
                     /locus_tag="ACFOV4_000525"
     CDS             17291..18076
                     /locus_tag="ACFOV4_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFC7618603.1"
                     /translation="MKHISSANNEHIRHLHRLLSQGKFRRQYAQTVLEGVHLLQVFLQ
                     SGGMPVGVYIPEAKMPSEEVRKLTAVLPEDGVFSVSDGILKKISSLTCADDVLALIDI
                     PDAGALPAGGDCVVLDGVQDPGNVGTVLRSAAAAGIGAVVLGKGCADAWSPKVLRAGM
                     GAHFLSEIYPQADLEIWLARYEDRVFATALREEKQAVLYNEDLREPTAWVFGNEGAGV
                     GKAVLDRADKCVRIPMHDATESLNVAMAATICLFEQMRQRSAY"
     gene            18086..18283
                     /locus_tag="ACFOV4_000526"
     CDS             18086..18283
                     /locus_tag="ACFOV4_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618604.1"
                     /translation="MPSEKIYYGVLIFLCIASMLLSPFFYAGALKPKKAALRKDGQWK
                     LILLSNTVAAAVLAWVWWKWF"
     gene            18545..18897
                     /locus_tag="ACFOV4_000527"
                     /pseudo
     CDS             18545..18897
                     /locus_tag="ACFOV4_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691158.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18909..19214
                     /locus_tag="ACFOV4_000528"
     CDS             18909..19214
                     /locus_tag="ACFOV4_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618605.1"
                     /translation="MRVSKIIGSMLLVTAVQTVFSANVYACRHNGKTSYSQTPGKHCT
                     NAGLGRDRVYSSVRPAVKDRAEDAGVGDYSDTVRDEHVQNPRENTHKDASNTGAKTH"
     gene            19276..20652
                     /gene="mpl"
                     /locus_tag="ACFOV4_000529"
     CDS             19276..20652
                     /gene="mpl"
                     /locus_tag="ACFOV4_000529"
                     /EC_number="6.3.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HFC7618606.1"
                     /translation="MKHIHIIGIGGTFMGGIAAIAKEAGFEVSGCDAKMYPPMSTQLE
                     ALGIGVHEGFDAAQLEEFKADVYVIGNVAKRGMDVVEAILNRGLPYISGPQWLAENVL
                     HHHWVLGVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENFSVSARLPQTPRQDPN
                     SQSPFFVIEADEYDTAFFDKRSKFVHYRPRTAVLNNLEFDHADIFADLGAIQTQFHHL
                     VRTVPSEGLIVCNGRQQSLQDTLDKGCWTPVEKFGTEHGWQAGEANADGSFDVLLDGK
                     KAGHVAWSLMGGHNRMNALAVIAAARHAGVDIQTACEALSTFKNVKRRMEIKGTVNGI
                     TVYDDFAHHPTAIETTIEGLRQRVGNARILAVLEPRSNTMKLGTMKSALPESLKEADQ
                     VFCYAGGVDWNVAEALAPLGGRLHVGKDFDAFVAEIVKNARTGDHILVMSNGGFGGIH
                     TKLLDALR"
     gene            20859..21911
                     /gene="bioB"
                     /locus_tag="ACFOV4_000530"
     CDS             20859..21911
                     /gene="bioB"
                     /locus_tag="ACFOV4_000530"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HFC7618607.1"
                     /translation="MTVSPVALRRKTECKPHPTARYWKKCDVEALFGLPFLDLIYQAA
                     EIHRQNFNPREIQLSTLLSIKTGGCPEDCAYCPQSAHHNTNLGKEQMMDVDEIVEKAK
                     IAKSRGASRFCMGAAWRGPKPKDVETVSAIIKAVKGLGMETCGTFGMLEEGMAEDLKE
                     AGLDYYNHNLDTDPDRYNDIIHTRRHEDRMDTLGKVRNAGLKVCCGGIVGMNETRAER
                     AGLIASLANLDPQPESVPINRLVKVEGTPLADAEDLDWTEFVRTIAVARITMPQSYVR
                     LSAGRSNMPEAMQAMCFMAGANSIFYGDKLLTTGNPDEDGDRILMEKLNLYPLQFELE
                     GEVAEVEKASGIKVDY"
     gene            complement(22058..22624)
                     /locus_tag="ACFOV4_000531"
     CDS             complement(22058..22624)
                     /locus_tag="ACFOV4_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFC7618608.1"
                     /translation="MNIKYSGIENRFETAILKKNGVRSGFVSFAPNLAAVKLNDYAKV
                     RKRITKTKQKADIVIVMFHGGAEGKQAEHLPFDTEIFYGENRGNVVEFARLAVDSGAD
                     VVFGQGPHVTRAVELYRDRFISYSGGNFATYGAINTSGISGIAPIFKIITNKQGKFIS
                     GTIIPITQADDKIPKIDPEKPLSGGLFI"
     gene            complement(22748..22987)
                     /locus_tag="ACFOV4_000532"
     CDS             complement(22748..22987)
                     /locus_tag="ACFOV4_000532"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618609.1"
                     /translation="MGGCTFFRRTAFVKQRAFEVADGNVRVLQGRFDVFQNIGIGQVI
                     DRIIAAEHNVAHADNGNGIGCLFVRRILSVHIAGI"
     gene            22974..23207
                     /locus_tag="ACFOV4_000533"
     CDS             22974..23207
                     /locus_tag="ACFOV4_000533"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFC7618610.1"
                     /translation="MQPPKICYAFRTPSAYGQYLADAGFDYLSFANNHSNDFGAQGIT
                     ATAASGSSFTYSIALKPLPITRPKLRKIPPSPR"
     gene            complement(23270..25129)
                     /gene="ilvD"
                     /locus_tag="ACFOV4_000534"
     CDS             complement(23270..25129)
                     /gene="ilvD"
                     /locus_tag="ACFOV4_000534"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HFC7618611.1"
                     /translation="MPDYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFT
                     QFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIAD
                     SIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQ
                     PERRLDLIDAMIESADDNVSNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSL
                     PGNGSYLATHAGRKELFLEAGRMIVEITKRYYEQNDETVLPHSIATKKAFENAMTMDI
                     AMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGG
                     IFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDVTNPENTRAIERFKAAPGGVRTTQ
                     AFSQNRMWKTLDLDREKGCIRDVAHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILK
                     FTGRARVFESQEDAVEGILGNQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLG
                     KACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIHLAISDE
                     ELAARRAEMEARGSKAWKPKNRDRYVSAALRAYGAMATSADKGAVRDIAQIER"
     gene            complement(25301..27070)
                     /gene="cysI"
                     /locus_tag="ACFOV4_000535"
     CDS             complement(25301..27070)
                     /gene="cysI"
                     /locus_tag="ACFOV4_000535"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA];
                     GO_function: GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HFC7618612.1"
                     /translation="MTVQTKTKGLEWQEKPLSNNERLKTESNFLRGTILDDLKDQLTG
                     GFKGDNFQLIRFHGMYEQDDRDIRAERAEAKLEPLKFMLLRCRLPGGIIKPSQWIELD
                     KFARENSYYRSIRLTNRQTFQFHGVPKTKLQTMHRLLHKLGLDSIATAADMNRNVLCT
                     SNPIESALHQQAYEYAKKISEHLLPRTRGYLDVWVDGKKVQSSDDFLQEDEPILGKTY
                     LPRKFKTAVVIPPLNDVDCYGNDLDFVAISDGGGQLAGFNVLAGGGLSMEHGNTKTYP
                     NISLELGFVPPEHALKAAEAVVTTQRDFGNRSDRKNARTRYTIQNMGLDNFRAEVERR
                     MGMPFEPIRPFKFTGRGDRIGWVKGIDGNWHLTLFIESGRLVDEGGKQLLTGVLEIAK
                     IHKGDFRITANQNLIVANVAEADKAKIEELARTYGLIRNDVSKLRENAMSCVSFPTCP
                     LAMAEAERVLPDFIDDLDKIMAKHGTSDDYIVTRITGCPNGCGRAMLAEIGLVGKAVG
                     RYNLHIGGDREGVRIPRLYKENITLPEILAELDDLIGKWAAERNIGEGFGDFAIRTGI
                     VKPVLNAPVDFWDASKAVAIARA"
     gene            complement(27097..28911)
                     /locus_tag="ACFOV4_000536"
     CDS             complement(27097..28911)
                     /locus_tag="ACFOV4_000536"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA];
                     GO_function: GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     flavoprotein subunit"
                     /protein_id="HFC7618613.1"
                     /translation="MSEHDMQNTNPPLPPLPPEITQLLSGLDAAQWAWLSGYAWAKAG
                     NGASAGLPALQTALPAAEPFSVTVLSASQTGNAKSVADKAADSLKAAGIQVRLAELKD
                     YKAKNIADERRLLLVTSTQGEGEPPEEAVVLHKLLNGKKAPKLDKLQFAVLGLGDSSY
                     PNFCQAGKDFDRRFEELGAKRLLERVDADLDFTASANAWTDNIAALLKEEAAKNRATP
                     APQAMPPADLQTVPESRYCKADPFPAALLANQKITARQSDKDVRHIELDLSGSDLSYQ
                     AGDALGVWFDNNPALVGEILDLLGIDPATEIQAGGKMMPVARALSSHFELTQNTPAFV
                     KGYAAFAHYEELDKIIADNAVLQDFVQNTPIVDVLHRFPASLTAEQFIRLLRPLAPRL
                     YSISSAQAEVGDEVHLTVGVVRFEHEGRARTGGASGFLADCVEEDGTVRVFVERNDGF
                     RLPEDSRKPIVMIGSGTGVAPFRAFVQQRAAENAEGKNWLIFGNPHFAADFLYQTEWQ
                     QFAKEGFLHKYDFAWSRDQEEKIYVQHKIREQAAELWQWLQEGAYVYVCGDAAKMAKD
                     VEAALLDVIIQAGHLNRDDAEEYLNTLREEKRYQRDVY"
     gene            complement(28908..30194)
                     /locus_tag="ACFOV4_000537"
     CDS             complement(28908..30194)
                     /locus_tag="ACFOV4_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit 1"
                     /protein_id="HFC7618614.1"
                     /translation="MTAQHQTPLRFITAGSVDDGKSTLIGRLLYDSKALLSDQIKTLE
                     SGKSNGLKETIDFSILTDGLEAEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRN
                     MVTGASTASAAVVLVDASQLDFGAQPLQLLPQTKRHSAILRQLNCPHIVVAVNKMDLL
                     DYSEDKFNAIVEAYRRLAEQLGLKDAHFVPVSALLGDNIVYPGGNMPWYKGEPLLSIL
                     ETLPGADEVSRTADDFYFPVQLVVRQDADKADDFRGYQGRIERGSVAVGQTVRIEPNG
                     LTAEVSEIITPKGEVAQAFAGEAATLRLDRDIDVSRGDLFVDKNSPLAPQKHLEATLC
                     WFDERPLNTARKYLLKHGTQTVPAKVGEIESVLDVRTLEQEAGAESLKMNDIAKVRIN
                     LQKPVTATPYAENTAAGSFILIDESTYGTVAAGMIL"
     gene            complement(30233..31156)
                     /gene="cysD"
                     /locus_tag="ACFOV4_000538"
     CDS             complement(30233..31156)
                     /gene="cysD"
                     /locus_tag="ACFOV4_000538"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HFC7618615.1"
                     /translation="MTKTEPNNAQLDWLESESIHIIREVAAECENPALLFSGGKDSVV
                     LLALACKAFRLGSRPVKLPFPLVHIDTGHNYPEVIAFRDAQAAKLNARLIVGRVEDSI
                     AKGTVVLRKETDSRNAAQAVTLLETIEANGFDALMGGARRDEEKARAKERIFSFRDEF
                     GQWNPKAQRPELWSLYNTRLHKGENMRVFPISNWTELDIWQYIARENLELPPIYYSHR
                     REVVRRRGLLVPVTPLTPKMPSETSEILDVRFRTVGDISCTCPVESTASTPTEIIRET
                     AVADISERSATRLDDQASEAAMEKRKKEGYF"
     gene            complement(31194..31934)
                     /locus_tag="ACFOV4_000539"
     CDS             complement(31194..31934)
                     /locus_tag="ACFOV4_000539"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenylyl-sulfate reductase"
                     /protein_id="HFC7618616.1"
                     /translation="METTLFKPALWQIPHIGSGGETALAEKTETLKQRLHRIVGSHRD
                     ARFASSLAAEDMVITDLIAGENLNIGIFTLDTGLLHTETLNLLDRLGRAYPHLRIKRF
                     RPVREDADRYVESKGRFAFYDSVEARRECCRIRKIEPLNRAIAGADAWLTGQRREQSA
                     TRTELPFAEYDAGRDIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQGFPSIGCDPCT
                     RPVKAGEDIRAGRWWWEGRNSKECGLHK"
     gene            complement(31945..33396)
                     /gene="cysG"
                     /locus_tag="ACFOV4_000540"
     CDS             complement(31945..33396)
                     /gene="cysG"
                     /locus_tag="ACFOV4_000540"
                     /EC_number="1.3.1.76"
                     /EC_number="2.1.1.107"
                     /EC_number="4.99.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0043115 - precorrin-2 dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0051266 - sirohydrochlorin ferrochelatase
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="siroheme synthase CysG"
                     /protein_id="HFC7618617.1"
                     /translation="MNYFPIFANLAGRPVLVVGGGAVAARKISLLLKAGAEVRVAAKH
                     LNAELSALAAENKILWLAEEFRAEHIRTVFLIIAASSDQALNRRVFHLAESCQKPVNV
                     VDDRDHCSFIFPSVIDRNPVQIAVSSSGSAPVLARLLRERLEALLPPSLGDMAEISGR
                     WRDAVKGKLKSVTERRRFWEKQFNGRFAALVKNRQNTLAERELAGQLEQSRQNDQGGS
                     VSLVGAGPGDAGLLTLKGLQEIQQADVVLYDALVSDGILSLVRRDAERIFVGKRARGD
                     RTPQEDTNALMVRLAREGRRVVRLKGGDPFVFGRGGEELETLARHQIPFSVVPGITAA
                     VGATAYAGIPLTHRDYAQSAVFVTGHRKADAPDIEWQTLARSRQTLVIYMGALKAALI
                     AERLQQHGRSPDTPAAVISQGTLPAQKTATGTLANLAELAETAPNPALIVIGEVVGLH
                     EKLAWFGENGEGENRVGQTYPALGGLNAGQRAA"
     gene            complement(33846..34502)
                     /locus_tag="ACFOV4_000541"
     CDS             complement(33846..34502)
                     /locus_tag="ACFOV4_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b/b6 domain-containing protein"
                     /protein_id="HFC7618618.1"
                     /translation="MKNKSKVWDLPTRLFHWLLAASLPFMWYSAKAGGDMLQWHTRVG
                     LFILFLLVFRLCWGIWGSDTARFSRFVRGWSGIRDYLKNGIPEHIQPGHNPLGALMVV
                     ALLAAVSFQIGTGLFAADENTFSTNGYLNHLVSEHTGSLMRKIHLNFFNLLAVFSAIH
                     IAAVAAYRVFKKKNLVLPMITGFKYIEGKTSIRFAGKTALAAALSVAALAAAAILLLS
                     "
     gene            34567..35457
                     /locus_tag="ACFOV4_000542"
     CDS             34567..35457
                     /locus_tag="ACFOV4_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFC7618619.1"
                     /translation="MFPVFHLSGESRRRMLQAALRFPYVFKARAEDSHKGTFGTLAVV
                     GGSAGMSGAPVLAASAAMYLGCGKVWAGFNQDALPFAVIAGFPEIMLDTADGLTKRQG
                     INAWVVGCGLGTDKAAVGTLAGILTEHTDKPVLLDADALNILSTDAETRNLARGCKNL
                     ILTPHPAEAARLLGTTVAQVQADRTAAVRKIRAIFGATVVLKGHKTLVASPDTEIYVN
                     ESGNAGLATAGSGDVLGGIIGSLLAQGVPVFEAACAGAWLHGAAADVIKESAGIAAGL
                     LAGEIAPAARWLRNRITESM"
     gene            35727..37538
                     /gene="typA"
                     /locus_tag="ACFOV4_000543"
     CDS             35727..37538
                     /gene="typA"
                     /locus_tag="ACFOV4_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFC7618620.1"
                     /translation="MKQIRNIAIIAHVDHGKTTLVDQLLRQSGTFRANQQVDERVMDS
                     NDLEKERGITILAKNTAIDYEGYHINIVDTPGHADFGGEVERVLGMVDCVVLLVDAQE
                     GPMPQTRFVTKKALALGLKPIVVINKIDKPSARPSWVIDQTFELFDNLGATDEQLDFP
                     IVYASGLSGFAKLEETDESNDMRPLFDTILKYTPAPSGSADETLQLQISQLDYDNYTG
                     RLGIGRILNGRIKPGQVVAVMNHDQQIAQGRINQLLGFKGLERVPLEEAEAGDIVIIS
                     GIEDIGIGVTITDKDNPKGLPMLSVDEPTLTMDFMVNTSPLAGTEGKFVTSRQIRDRL
                     QKELLTNVALRVEDTADADVFRVSGRGELHLTILLENMRREGYELAVGKPRVVYRDID
                     GQKCEPYENLTVDVPDDNQGAVMEELGRRRGELTNMESDGNGRTRLEYHIPARGLIGF
                     QGEFMTLTRGVGLMSHVFDDYAPVKPDMPGRHNGVLVSQEQGEAVAYALWNLEDRGRM
                     FVSPNDKIYEGMIIGIHSRDNDLVVNPLKGKKLTNIRASGTDEAVRLTTPIKLTLEGA
                     VEFIDDDELVEITPQSIRLRKRYLSELERRRHFKKLD"
     gene            complement(38102..38192)
                     /locus_tag="ACFOV4_000544"
     tRNA            complement(38102..38192)
                     /locus_tag="ACFOV4_000544"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38156..38158),aa:Ser,seq:gga)
     gene            complement(38231..38317)
                     /locus_tag="ACFOV4_000545"
     tRNA            complement(38231..38317)
                     /locus_tag="ACFOV4_000545"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38281..38283),aa:Leu,seq:cag)
     gene            complement(38353..38439)
                     /locus_tag="ACFOV4_000546"
     tRNA            complement(38353..38439)
                     /locus_tag="ACFOV4_000546"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38403..38405),aa:Leu,seq:cag)
     gene            38528..40903
                     /gene="rnr"
                     /locus_tag="ACFOV4_000547"
     CDS             38528..40903
                     /gene="rnr"
                     /locus_tag="ACFOV4_000547"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFC7618621.1"
                     /translation="MNKNIKSLNLREKDPFLSREKQRYEHPLPSREWIIELLERKGVP
                     SKIESLARELSITEDEYVFFERRLKAMARDGQVLINRRGAVCAADKLDLVKCRVEAHK
                     DGFGFAVPLTPAKDGDFVLYERQMRGIMHGDIVTVRPAGIDRRGRREGTVLDIVERAQ
                     SKVVGRFYMDRGVAILEPEDKRLNQSIVLEPDGVARFKPESGQVIVGEIEVYPEQNRQ
                     AVAKIIEVLGDYADSGMEIEIAVRKHHLPHQFSEACAKAVKKIPDHVRKSDLKGRVDL
                     RDLPLVTIDGETARDFDDAVFAEKIGRNYRLVVAIADVSHYVRPDDAIDTDAQERSTS
                     VYFPRRVIPMLPENLSNGICSLNPNVERLCMVCDMVITYAGNIKEYRFYPAVMRSHAR
                     LTYNQVWKWLSGGIGHPFKTQIDTLYKLFKILQKKRFERGAVEFDSIETQMLFDDNGK
                     IEKIVPVVRNDAHKLIEECMLAANVCAADFLLKNKHTALFRNHLGPTPEKLATLREQL
                     GLLGLQLGGGDNPSPKDYAALVEQFKGRPDAELLQVMMLRSMQQAVYEPHCDGHFGLA
                     YEAYAHFTSPIRRYPDLTVHRAIKAVLNQQTYTPKKSWQALGVHTSFCERRADDASRD
                     VENWLKTYYMRDKVGEVFEGKISGMTSFGIFVTLDGIHIDGLVHISDLGEDYFNFRPE
                     IMAIEGERSGIRFNMGDRVAVRVARADLDDGKIDFVLIAGGSGRGRKVKSSASAKPAG
                     TAGKGKPKTAAEKKTARGGKVRGRGASAAAESGKKAKKPVPIKVKKRKGKS"
BASE COUNT         9211 a        10720 c        11607 g         9375 t
ORIGIN      
        1 aatctatcgg aaaaaacaga aacccccgcc gccgtcattc ccgcgcaggc gggaatccag
       61 accccaaacg cggcaggaat ctatcggaaa cggctgaaac cgaacggact ggattcccgc
      121 ctgcgcggga atgacggaaa gtggcgttcg ggattcccgc cttcgcggga atgacggaaa
      181 gtggcgggaa taacgaaagg cgggaatgac cgcgcaaaaa gccgctgccc ccttcggacg
      241 gcaccggcaa caaaaaaccg cacggccgaa accgcgcggg aaaggatagt cgggcgcgcc
      301 cgataagcag cggccgcccc cgttatttca attgggcgac atattggcgc aaaacctcgt
      361 tgatgcgcgt ctgccagccc ttgccgccgg cgcggaattt ttcgaccaca tcggcggaca
      421 ggcgtatggt aacgagttgt ttcggggttt tgcctgtgtt tcgtttttgc attacgccct
      481 tttcttccaa ttgtttttga tgggaaaaaa gcacctgtgc caagtcttcg ggcagggctt
      541 cggcaatggg gcgggcaagc gcaaaatctt cggcggcaag ttcccgcact tcgccgtcag
      601 cgtttgttaa ggattgacgt tgcatatttt ttaacctctc ttttattcgc tttgcgaaaa
      661 ctgatgacac ggatgccgtc ttttatcggc gtaaaacaga caatgtgcag gcgttgcgta
      721 tcgcctagat aagcagcggc aacataacgc ggttcggggt aatcaaagca gacatcgggc
      781 acaataacgg ccgttgtcca gcgtatttgc ccgactgatt caaagggcaa attccgctct
      841 tcgatattgc gttgattttt ttcggagtca aattcaatct tcattgcagc ttgcagcgta
      901 ttttgtcgtt acattataag cggcaaaaaa ccaaaatgta aatacaaaaa aggaaacccc
      961 gaaatgacca tctatttcaa aaacggcttt tacgacgaca ccttgggcag catccccgaa
     1021 ggcgcggttg ccgtccgcgc cgaagaatac gccgcccttt tggcaggaca ggcgcagggc
     1081 gggcagattg ccgcagattc cgacggccgc cccgttttaa ccccgccgcg cccgtccgaa
     1141 taccacgaat gggacggcaa gaaatgggaa atcggcgaag ccgctgccgc cgcccgtttc
     1201 gccgaacaaa aaaccgccac ggcattccgc ctcgcggcaa aggcggacga actcaaaaac
     1261 agcctcttgg cgggctatcc ccaagtggaa atcgacagct tttacaggca ggaaaaagaa
     1321 gccctcgcgc ggcaggcgga caacaacgcc ccgaccccga tgctggcgca aatcgccgcc
     1381 gcaaggggcg tggaattgga cgttttgatt gaaaaagttg tcgaaaaatc cgcccgcctg
     1441 gccgttgccg ccggcgcgat tatcggaaag cggcagcagc tcgaagacaa attgaacacc
     1501 atcgaaaccg cgccaggatt ggacgcgctg gaaaaggaaa tcgaagaatg gacgctaaac
     1561 atcggctgaa aaaatacgtt taccacctgt tggtagccat cgaccaactg ttcaacgccc
     1621 taaccggcgg cgcggcggac gaaaccctct caagccgcac ctatcgcggc gcgcggctcg
     1681 cccaaaagcc caaaacccgc tggaaggttt tatacaccct gatcaacggc gtatttttcg
     1741 accgccaaca ctgccggcag gcgtatatca gcgaactgaa aggcaggcag cacgacgcgc
     1801 ggttcaacca aagccgcgcc gccggggaaa aggggacgcg atgaactact tcggcatggt
     1861 agagtttctg cgcctgatgg caatggtgcg gccgccattt gtcttcttct ccggcacccg
     1921 cagcgaactg cctacttatc ttgacctcgt ggcagaactg cgcctgaccg gatgggagcg
     1981 ttttgcaggc agccaaacct tgactgtgag cagcacatca acagcaattc aagctacgac
     2041 gaccacctga tttataagtt ctgaccgcaa gtagcgtact acttttaaag gcataagata
     2101 atccccgttt aacagaccat taaacgggga taaatttgtg caaaagctaa tacaatttcc
     2161 tacgcttcgg cggtgcaaaa gctgccgcca attcgtgcaa aagctgccgc cgccttacat
     2221 tccagtgcaa tgccgtctga aacttcgcta atctcgggtt gccgcgcgct gtgttgttct
     2281 tcggtactca gcaaaaagcc gtacagacgc tccaatcggg cgcggtaggc ggtgaatttg
     2341 ttgtagaaca tccggaaaaa agatagcgcg ttttgcagtc gcgcaaaggc ttggacggtc
     2401 tgctggatgt cgccgatttt gatttgtccg gcaaacaggc gcggcgcttg caaaataatg
     2461 gggaagagtt tgatgccgtt ggtgaacata tcgttaaagc cgcttaagca gacgctttgc
     2521 cgcgcgatgc gccaacggtt gcggataatg gctttaaagc ggtcggaaag ccggccgtgt
     2581 tcgtgttgtt cgccgttgta aaacgctacg ctttcggcgt ggtcgcgtac gcggatgagg
     2641 gaataacggt agtcgccgtt gagtttttcg ttttcatagt tgtaacgaat caaggggttg
     2701 cctatccaca tcgcgataaa ggtcgccaaa atcacaaaaa taaagacgag ccaaacaatg
     2761 ccgcgcggaa tgtcgaagcc gaacacggtc aggatgccag ccaagcccca caaaacaacg
     2821 gcaaattcca aagaggtaac gaccgaattg accatgccgc gtacaaattc gatggtcgaa
     2881 gcgatgaaat cctgcgcgtc ctgttggata cgttggtcga tgttgtccgg cgcgtggcgg
     2941 cgcatttgca ggcggtagta gtttttgtcg gcaagccagc gcgtcgtcag cacttcattg
     3001 agctgctccg accatttaat cgccaagcct tgatcgagga agtcgttgac gacattgtta
     3061 aacgcccgta tcagcaccac gcccgcgttc atcgcggcaa acatccaaaa cgcggaggcg
     3121 ttcaaatcct gcatcgagtc gtaaagtcct ttggacataa aggtactcaa cacattcagc
     3181 cgtacttcgg tcaacagcag cgtaaccatt accgtaatca gcagcaagac tttgaccgtg
     3241 cttttcggtg tcaggcaaag ccaaagcggt gtggaataaa gctcggtttg ccatttctgc
     3301 atgggaaatt tcttacggta tcaatgccgt ctgaaaaaga cgggtacagt tgattttttg
     3361 atgaagtttg gggaagtttt gccggtcagg gtacattgcg tgttaattta tagtggatta
     3421 aatttaaacc agtacagcgt tgcctcgcct tagctcaaag agaacgattc tctaaggtgc
     3481 tgaagcacca agtgagtcgg ttccgtacta tttgtactgt ctgcggcttc gtcgccttgt
     3541 cctgattttt gttaatccac tataccatac aaccacgccg gaattaagtt taaatttgaa
     3601 taaaaggttc gggttctgca aaatacagaa cccgaacctt gttcggatat tgaaaccggc
     3661 cgcccgattt tgggcggtgc ggcttgcaag tatcaagatt cgcatatgcc gtctgaagct
     3721 cggagaggtt cagacggcat atgcttattt gggctgctct tcgacgaatc tcggaccttt
     3781 caagatgccg ttgtgagaat agggcgacag caggttgtat gcggcggttt tggaaacctg
     3841 ataaccgcgg tcggtcaggc tgttggcaat ctgattgacc actgcgctga ccaaagcccc
     3901 caacaggccg ctgttgctgt tgttgctgcc ttcgcggatg ctggccgaac ccgaccacaa
     3961 ctcttttccg ttgcgggaat cgaccagccg tgctttggcg gatacggtcg tcacgctgtc
     4021 taaaatttga tatgaagtgc cgtattcggt aaccgtaatg tacaaaaccg catcattgcc
     4081 gaaaatctga tgcagttttt ccggccggac ggcgtgaata tcggcggcat tggtcaagcc
     4141 gttttgtttg aaggtttcct ccacgactgc ggcggggaag acgtaatagc cggcttcgga
     4201 aagcggcgcg gcggtcgaag ccagtacacc ccatgttccg ttgacatcgg gcgattcgtt
     4261 cagcggcgga accaccaaaa ttgaagccgg tttgctttcc ttgaatgacg tgtagtcgaa
     4321 atcgggcgct ttttgaactt ggcaggcaga cagcgccaac acggcggcaa gccctaaaat
     4381 caaaggtttc atcgcttgcc tcctttacct gttttcatca ggaagtccat aaatacgccc
     4441 gattcgggaa acagcctttt ctcttcttca aactggcgga acgcgccctc tttgtctccc
     4501 gaacgggaaa gcagcagtcc cagatgggcg tgcgcacccg gggcggcatt catttttttg
     4561 ttgccggctt ccacaaagta tttttccatc ttttcggtct gcttgcccaa cgaagtgtcg
     4621 tcgtttttca aaccttcata gacggtatcg ggatagccgc cgtaataata cagggatttt
     4681 tgcccgttgc cgccgcaggc ggtcagagcc aagaccgccg cacacagcga caaacggctc
     4741 aaggttttcg gattcatcat ttctccttaa cggttgggtt gccatgcgcc gttgtcaaca
     4801 gcctgaacca ggctgttgac ggcttcgcgg attgccaagt ctaaaacttt gccgttcaaa
     4861 gtcgcatcgt agccggaagt gccgccgaaa ccgatgattt cacggttgga aagtgcgtat
     4921 tcgcccgcgc cctgtgcgga atagacgatt tcggaagtat tgacgttgac gatattcaga
     4981 gccacttttg cataggcgat ttgcgatttg ccgcgaccca aaatgccgaa gagctgatga
     5041 tcgccgacat ctctgcgtcc gaattcggtt acatcgccgg taacgacata atctgcgcct
     5101 ttcaggttat gcgctttgcc ggaaatgccg gattcctgtt ttaatgcgtt caaattggtg
     5161 cggttcagta cgttgaagcg gttggtctgt tgcaggtgcg ttaccagaat ggtttttgcc
     5221 tggctgccca aacggtcttc cccgtcggag aaaatgcctt tttggaagct ggagcggttg
     5281 tcgaatgttc cgacggaaat cggggtacga acaccgtgat attgcgtatt gtaggaggcg
     5341 actttctcta cctcgagact gcgtgaggat tcggtcgcac agccggtcag tgaaacggca
     5401 gcggcggcaa ggacaacggc ggtggaaacg gttttcataa aatttaccct aaggtcaagt
     5461 taaggaaata acgggttatc attattgtcc ttatgtaaat ttaagtcaag gtgtttgtct
     5521 gtgcgggacg gatgcgcgcg gaaggtacgg atatttttca aacggaatcg cggcgcgggc
     5581 gggatgcctg ccttttccgg atttagaggt aaacgatttc gccgctccgc cctttgcttt
     5641 cggtacttgc ccaccagaca aatgcgggca gcacgtcccc gtagcttttg cgttcgcttt
     5701 tggcttcgcc cggatgggat ttgatgcgtt gcggggaatt gatggggccg gggacgagga
     5761 cgttggcgcg caggttgccg aagcgttccc attcgtcggc ggcgactttg cacaggtagt
     5821 tcaacgcggc tttggacgcg ccgaagccgc cccagtaggc tttgggtgtt tcgccgtggc
     5881 tttcgccgac gaagatgacg gacgcgtcgg gcgactgctt cagcagcggg aacagggcgc
     5941 gggtcagccc cataggtgcg acggtgttga tgcggtattg gttgacccat tcggcgacgg
     6001 tttggaaatc cagcggcgag agggcgtaaa aatagccggc gcagtggacg atgccgtcca
     6061 gtttgccttg cgtggcttcg gcaatggtgg cggcgaactg attgaattct ttttcttccg
     6121 cactcatcag gtcgaaacgg atggcgaagg gttcggggtg tccggcttcg acaatcgcgt
     6181 catagacttt ttccagtttt ttctgatggc gtgccaccag aatcacggtt gcgcctgccg
     6241 ccgcataggc tttggcgacc tgttcgccca gaccttgcga tgcgccggta attaagatgg
     6301 ttttgtcgga cagtgtcgcc atactttttc ctttttggtg gtcggtcggg ggtattttag
     6361 cgttttgccg caccttgtaa agcgtcccga taccggccgg cgttttcaga cggcatcgct
     6421 caggctttgc aggcaggctt ccgccgacgc gaaacctgat tgtacggcgg cttcgagcgt
     6481 ggcggggtag tctgggtgga ggtagtcgcc ggcggggaag atgcggtgcc ggtgcaacca
     6541 cgacaaatcc ggcggcgggg catcggctgc ggttgtggcg cgtttttcgg tgatgacgcg
     6601 cacggcttcg ggttcgccca aatgcggaag gatgcgtttg aggtcggcgt gaactttgtc
     6661 cgcccacgct cggtttgtaa acgcgccgac gcggtcggaa acgctgatga cggcggacac
     6721 ttcgttttca ggcagtccga gcctgccccg gcaaagcaac cattgtgccg tgccgtcggc
     6781 aaggccggtc agcggggcgg gcaggcggac gggttcggcg tagcgcagat agacggtggt
     6841 gatggcgtga tagcgaaggt tttgatatgc cgtctgaacg tgttcgggcg tgccttcggg
     6901 caggagcgcg gcggcgtggt agggcgcggt ggcggggacg gcggcatcga aagcttcgcc
     6961 gttgacgagc actttcccgt ccgggagggg gttcagacgg catacgcgcg tttcgaggcg
     7021 gatgtccgcg ccgagccgtt gaagctccgc caaggcaggt tcggcgacga ttgcgcccaa
     7081 atcctgcttg ggtaggagat agtcgctgcc ggattttttc gtcagcacgc cgtcggacaa
     7141 aacgttgcac aacacgcgca ggcttgcggt ttccaaaggc gtgttgagcg caccccacac
     7201 cagcggctgc caaaactgca tcacggcggc acgcggcacg ttccgctgtt tcagccattg
     7261 tgcaactgtc gtgtcgggct gtccgaggcg tgcggacttc tgcaaatcgg acatatcggc
     7321 aagcagtttg cctttgaatg cggacggtac gcgccgggca agcagcacgc cgcccaaaat
     7381 atgcagcggt gcgggcaggg ggagggcgcg gaactgtaaa ccgccgtgca tatgccagtg
     7441 cagcggtacg cgcaaaaagg cggcacgggg gtctgaaccg atggttttca tcaggcgcaa
     7501 cacgccccgg tatgcgccga gcaaaatgtg ctgcccgttg tccaaaaaac cgaaaccgtc
     7561 ggtatttccg gccagtgcgc gcgccctgcc gcccgcctgc cggccggctt caaacagggt
     7621 aacgtcggcg taccgcgcca aggtgacggc ggcggacagt cctgcccagc ctgcgccgat
     7681 gacggcgatt ttcgggcgcg gatgcggcgt gttcatcatt tattcctcca atggttttgc
     7741 agccgtatct atttccgttt ctgaaaatga cggtagaaaa ggatacaggc taaaaataaa
     7801 ggcagcagaa agcgcgcata gggatatcac ggatggtctg catgccagta tccgtaccgt
     7861 ccctgtggaa cggtatcata gcggtaattg tcggggaaaa agttgatcca aaccgttact
     7921 gccggccata aggctatatc cctgactgct ttcatttgct tctgctcctg tttaaattcc
     7981 cggcaattcg atttcaaagc gcgaacgcca acgggattgc gcggttacga tgcagacttt
     8041 cagacgatgg ttgaaacccc gtccggcggg gctgtgggaa tcgggtttgc ctgacgggcg
     8101 gcgggcggta tgcgccttat gcccgttccg gcgtgccggg gcgcggtttg aatccgaata
     8161 accaggtttt cagggcaatg cgttttttgc gcggcgaagg gagggcgatt ttgtatttga
     8221 ggacgttttg tgcgccgtcc cggtcgattt cgttcaatag ctcgtaataa accgccgcca
     8281 taaccagtcc gactttttgg gcttttttat cggcagccgg cagcagcgat acggcttcgc
     8341 agtaggtttc acgggcgcgt ttgatttgga acgccatcaa ttcggcaaaa ttgcccgtcg
     8401 ggctgcattg caaaatcacg cttgcgggta cgtcaaaccg ccgcatttcc tccatcggca
     8461 ggtaaatccg tcccctgcgc gcgtcttcgc cgacatcgcg gatgatgttg gtcagttgca
     8521 gcgcaagtcc catcttgtcg gcgtattcca gcgtttggtc gtctgaaaac cccaaaatcc
     8581 gcgcaatcag gcagccgacc acgcctgcga cgcggtggca atacagtttc aattcttcaa
     8641 aactgccgta acgggcttga accaaatcca tctgcatccc gtcgattaag gcttccagtt
     8701 catatttcgg cagcttgaag gtttccttaa cttgccgcaa ggcctgattg acggggtgtt
     8761 ccggcatcgc gccgccgaat accttgtcca aatcgccgcg ccaccagttc aatgtcgcct
     8821 gtgcaacatc ggggttggaa cattcgtcaa ccacatcgtc caattcgcgg caaaaagcat
     8881 ataaaaccgt taccgcatcc cgtttttcct gagtcaggaa acggaagccc gacaaaaaac
     8941 tggagcggct ttcttctgct ttttggcggc aatagtcgag tcctttcacg atttatattc
     9001 ctaatgatgg gcgggaaagg cggattttat cggcatttgg cggtagaggg caatttcggc
     9061 ggcacgacct aatccttagc ggtttgctca actatcggcg caaattctgt taaaatgccg
     9121 ctttccttcc tttacacacc gcaccgacag gcagaattta tggctctttt gcagatttca
     9181 gaaccgggta tgtccgccgc cccgcaccgg caccgtttgg cggcaggcat cgatttgggt
     9241 acgaccaaca gcttggtcgc caccgtccgc agcggcagtg ccgcctgcct gcccgatgcc
     9301 gaagggcgcg ttaccctgcc ttccgtcgtc cgctatctgg aaaacggcgg cattgaagtc
     9361 ggcaaaaccg ccctgtccgc ccaaaaaacc gacccgctga acaccgtcag ctccgccaaa
     9421 cgccttatcg ggcggacgct tgccgatctg catcaaaata cgcactacct gccttaccgt
     9481 ttcggcggca atcaacgcgt tatcgaactg catacgcggc agggggtgaa aacgcctgtc
     9541 gaagtgtcgg cggaaatcct caaaaccctt aaatcgcgcg ccgaagaaac cttgggcggc
     9601 gatttggtcg gcgtggtgat taccgtcccc gcctatttcg acgatgccca acgccaggcc
     9661 accaaagatg ccgcgcgtct ggcgggtttg aacgtattgc gcctgctcaa cgaacccacc
     9721 gccgccgcaa tcgcctacgg gctggacaac gcctcggaag gcacgtttgt cgtgtacgac
     9781 ttagggggcg gcacattcga cgtatccgta ttgcaactga ccaaaggact gtttgaagtc
     9841 aaagccaccg gcggcaacag cgcgttgggc ggcgacgatt tcgaccaccg cctgttctgc
     9901 cgcctgctcg aacaaaacgg actctcccaa ctcaacgaac aagacagcca actcctgctc
     9961 tcgctcgtcc gcgccgccaa agaacaatta accacgcaaa ccgaagcgcg cattcaggcg
    10021 acgctttcag acggcatgcc aatcgacaca agcatcagtc gcgccgagtt ccacaacctg
    10081 acgcagcatt tggtgatgaa aacgctcgaa ccggtcacac aggcgttgaa agatgccggt
    10141 gtcggtaaaa acgaagtcaa aggcgtgatt atggtcggcg gttcgacccg tatgctgcac
    10201 gtccaacagg cagtcgccac cttcttcgga caaaccccgc tgaacaacct caatcccgac
    10261 gaagtcgtcg cgctcggcgc cgccatacag gcaaacgtcc tcgcaggcaa caaaaccgac
    10321 ggcgaatggc tgctgctgga cgttacacct ttgtcgctcg gtttggaaac ctacggcggc
    10381 ttggcggaaa aaatcatccc gcgcaattcc accatcccca ccgcgcgcgc gcaggacttt
    10441 actaccttca aagacggtca gaccgcgatg acgatacacg tcgtacaagg cgagcgcgag
    10501 ctcgtttccg actgccgcag ccttgccaaa ttcaccctgc gcggcattcc gcctatggcg
    10561 gcgggtgcgg cgcgtatccg cgtaaccttc caaatcgatg cggacggtct gctgtccgtt
    10621 tccgcccaag aacaaagcac cggcgtacag gcgcaaatcg aagtcaaacc ttcctacggc
    10681 ttggacgacg acaccatcac ccaaatgctc aaagacagca tgagcaacgc cgccgaagac
    10741 atggcggcac gtgcccgagc cgaagccgtg gtcgaagccg aaagcctgac cgatgccgtc
    10801 aacgccgccc tcgagttgga cagcgatttg ctggaagccg aagaattgca acagattcgg
    10861 caaggcatcg ccgatttgca aggccgtgtg aaagacggaa aagccgaaga catccgtgcc
    10921 gccgccgcca aactcggcag tattaccgac aatttcgccg ccaaacgcat gaaccgcaac
    10981 atccaacgcg cgttgactgg tcaaagcgtt gataatattt gacggcaaat ggtttcagac
    11041 ggcatagata taacctgata ccgtctgaag gctcgaaaac acttgaaaaa catcgatatg
    11101 gaaaagtcag gcattgtcta tctgatgaaa accgtcatca agggcgtgta taaaatcggc
    11161 atttcggacg taagcaattt tgaaggcaga atgcgccatt tggaaaacaa cggctatgcg
    11221 aacgttgccg gattggaacg catcctcgcc gtcaaaaccg acaattacaa agaaaaagaa
    11281 aacctgctcc atgaaatttt tagtaaaagc aggaccgaat tgttcgccgt ggacgagaat
    11341 cttgtaaaac gtttgttttt atcgcttcgc ggcgaaatcg tgttcccgaa aaacgaaacg
    11401 gcggaatcgg aatttgaaaa aagcgtccac gaacgcaggc aggaagggaa tgccggatcc
    11461 ggtcgcaaac aactgcttga tttggtacgg cgcggacacc gggaataccc ttacgcgctg
    11521 ccccggcttt tggcgggcgc ggcatcctac aagccgaaaa aatcgaaaat ccgccttttt
    11581 aaagaagcat atttacgcaa aagcggtacg aggctgaccg acgaaattgc agacggcatc
    11641 catatttaca cctgtttttc gcgggcggat ttggaaaaag cctattccga atatttggaa
    11701 cttttcaaat ccgaatcgga tgccgaaggc agaaaaccac ggtaaggtgc aaacagatac
    11761 cgtacacgtt gaggagcagt atgatgggcg attccgtcat ttattatgta gaacaggcag
    11821 acgaaccggt aaaccgtgcc ggcgaacgcg cccgtaaaac attcaaatac ttttggcgcg
    11881 agcttttttg ggaacgccgc cgcatcattc ccgccttaga ttttgccatg gtcaaagccc
    11941 cttttttcca agacggcgaa gacggcgaaa tttgcgaaca tatgtggatc gacgatattt
    12001 attttgacgg tctttacatt tatggcgtgc tgaacaatga acccggcgaa ctgaccaatg
    12061 tcgaacaagg cgaaagcatt tgcgttccgg ttgacgacat cagcgactgg atgttcgtgt
    12121 gcaacggcat tccctacggc ggctttaccg tacaggcaat gcgcgggcag atgacggaag
    12181 aggagcgcac cgaacacgat gccgcatggg gaatcgattt cggcgatccc gggcagatat
    12241 tgctggtgta tgaagaaaaa gaacatcccg aaaatctgga agagcatccg atgtgccgga
    12301 actgtattga cgattttcgg caacagttgt cccaaaattc ggattttctg catgagcagg
    12361 acgaagacgg ctatacgccg cttcatcatg aagccatcgc aggaaatgca cttatggttc
    12421 aagccatgct tgaatatggc gcaagtcctg cctcaacgac atcggaaggc tataccgccc
    12481 tcgattttgc ccgcctggcg ggctggcaaa atgttgccga cctgctcgaa ccgagacatt
    12541 aggcagacag ttttccgaaa aacggacgca accacttttt acagaaagac aataaaaatg
    12601 cccaaaatta ccgtacttcc acacgcgacg ttatgccccg agggtgcagt catcgataac
    12661 gcgccggaag gcaaaaccgt cctcgacgta ctgctcgacc acgacatcga agtcgatcac
    12721 gcctgcgaaa aatcctgcgc ctgcaccacc tgccacgtca tcatccgcaa aggtttcgac
    12781 agtttggaag aaccgaccga attggaagaa gacctgctcg accaagcatg gggtttggaa
    12841 gccgattcgc gcctgagttg tcaggcggtt gtcgccggcg aggatttgat tgtggaaatc
    12901 cccaaataca ccatcaacca cgcgcgcgaa gaacactgaa aacaggccgt ctgaagccgg
    12961 cacgcttcag acggcattgt tgcgcggata aggcgcaatc gcccgaaaac aggcgttcgt
    13021 acaggcggaa ctttcgattc tatagcgaat taacaaaaat caggacaagg cggcgagccg
    13081 cagacagtac aaatagtacg gcaaggcgag gcaacgctgt accggtttaa atttaattca
    13141 ctatatattg atttttatcg gttttctgac ggaacggatt ggtgcggcat ccgaggcgga
    13201 ttactcgggc gcgatgcacg ggtatttatc ggttttgcag ccggaaaaac cgccggcggg
    13261 ttactttcag ggcggcggtc gggcggtatg ccggatagcg ttccactttc gcttctatat
    13321 tgattttgat tggttttctg acggaatgac ccgatgcggc atccgggacg gcttgtgttt
    13381 tttcctgccc gcctgccgga ttttcccatc cttgcgtgaa accgaaagag acggcggcgc
    13441 ggcggacaag ctcgagatag cgtccttcaa gctccgggca ggcggcggac acgctttctg
    13501 ccgtaaccgt gaagccgccg cccgacccgg aaaggcgttc cgcaatctgc gtgtagatac
    13561 gccaacgttg ggcgcgcaac attgccgcat cgcaaccggc agccgcttta tccaaggcaa
    13621 tcaggccgcg ccggttttgg tggtgaaggc aaaccgttac tctggagagg atatgttgcc
    13681 cgtccaatat ttgatacagt ttgcgtatca gcagaatcag gcggtcaaac tcctccatct
    13741 ccgacaggga atcaggatgg tcggaagcgg tataaaccag tttggacaat tttgcggcaa
    13801 acatattgtt catcaatctt ccttgtcggt tgaaaccccg ctcttcgggg cggtagaatc
    13861 agatttgttt gggagggaca actcctccca gatcaggacg acacataggc tggtgcttga
    13921 tgtgttgtcc ggcgagttga aacattcagc catcctcaag gtgcggcagt tttgccgaaa
    13981 catattctac acggcttcaa tgccggacga taaaaggaaa ttcatatgaa atggaccgac
    14041 acccggcgta tcgccgaaga actctatgac ctgcacagcg aaaccatcga tcccagaacc
    14101 gtgcgcttta cccaactgcg cgacctgatt atggcattgc ccgaatttga tgacgatccc
    14161 gcccgttgcg gcgaacgtat tctcgaagcc gtgcagcagg catggataga cgaggcagaa
    14221 taagtttcgg gaatgccgtc tgaaatacgg cggtacgcgg ttcgtgcttc tgtttgcagt
    14281 gggaacggtt ttaccagtct ccttttttca gcctatccag ttggcggcgg tcgcgcttgg
    14341 tcggtctgcc gtcgggatgg gcggaagtga tgcggctgaa ttggtcgagc tgtttgcgct
    14401 cttccctcaa tgctgccgtt tttgcgtctt cttcatacag aagccgcgcc tcggatgccg
    14461 ggcggcgttg gtggttcaaa cctttaacct tgattttata gggaagggaa ttgagcgtca
    14521 ggtcgataat atcgccgatg tctatggttt tactgttttt gaccttcgag ccgtttactt
    14581 gaaccctacc cagttcgatg tgcttttgcg caagggaacg ggtcttgaaa aaacgtgccg
    14641 cccaaagcca tttgtccagc cgcatggcgg aagaatcgtg cttgtctttc atacgatttt
    14701 gtttgaaata attgaatttg tttcgagttt agcataagat acgccgccta taactagtat
    14761 atatgcacta atccactgtt ttccatgctg tccgaacaca aaaagagggt gtggaaaagc
    14821 cgttttggac aataaattaa ctgcggaata tgcacaaata gcgtatgata gcggcagaat
    14881 ctgttgatga gagcttcatt ctatgaaacc tgtttttttg gattttgaac aacccatagc
    14941 cgaactgacc aacaaaatcg atgagctgcg tttcgtccaa gacgagtctg ccgtcgatat
    15001 ttcggacgaa atacaccgtt tgcagaaaaa aagcaacgac ctgaccaaat cgattttcag
    15061 caaactcaca cccgcccaaa tttcacaggt ttcccggcat ccgcagcgtc cctatacttt
    15121 ggattacatt gaggcactgt ttaccgattt tgaagaactg cacggcgacc gccactttgc
    15181 cgacgattat gcgattgtcg gcggattggc gcgtttcaac ggacaaagcg tgatggtcgt
    15241 cgggcatcag aaagggcgcg acaccaaaga aaaaatccgc cgcaacttcg gtatgccccg
    15301 tcctgaaggc taccgcaaag ccctgcgcct gatgaagacg gcagaaaaat tcggcttgcc
    15361 cgtcatgacc tttatcgata cgccgggcgc gtatcccggc atcggcgcgg aagaacgcgg
    15421 acagtcggaa gccatcggca aaaacctgta cgaactgacg cgcctgcacg tccccgtttt
    15481 gtgtaccgtc atcggcgaag ggggctcggg cggtgcgttg gcggtcgccg taggcgatta
    15541 cgtcaatatg ctgcaatatt cgacctattc tgttatctcc cccgaaggct gcgcttcgat
    15601 tttgtggaaa accgccgaaa aggcggcgga tgcggctcag gctttgggca ttactgctga
    15661 ccgcctgcaa aagctggact tggtcgatac cgtcatcaaa gaaccattgg gcggcgcgca
    15721 tcgggatttc gggcaaacca tgaaaaacgt aaaagccgtt ttggaaaaac aactgcacga
    15781 agcgcaaagc atcccgcttg ccgatttgct ttcgcgccgt ttcgaccgca ttatggctta
    15841 cggcaaattt tcggaacaat aattcaggta gaacaagcag caagcagttt gtctgaaact
    15901 gcttgctttt tctttatcgg gacggaaccg tgctgacttt agatgcgttt gagcaatgct
    15961 tgaaggattg ttttcctcaa ggtctgaatg gaaaaaaaac agcggtggca ttaagcggcg
    16021 gcttggattc cgtcgttttg ctgcatctgc ttgtccgcgc cgggaaaaaa ggcggtttta
    16081 ttccggatgc attgcatatc catcacggct tgagtccccg tgccgacgat tgggcggatt
    16141 tctgccaaaa ctattgcgat atgctcgggg tggggctgga aacggttaag atctgcgtgg
    16201 aaaaaaacgg tttgggcatc gaggcggcgg cgcggcaaaa gcgttatgcc gcgtttgccg
    16261 aaaaaggctt tgacgttttg gcgttggcgc accacaggga cgatcaaatc gaaaccttta
    16321 tgctggcggt cgcgcgcggc ggcggtttgc gcgctttggc ggctatgccc gccgtccgcc
    16381 cttttgggga aaaaggcatt atctggcggc ccttgctgcc tttttcgcgc caagatatat
    16441 gggattatgc ccaaaaacac ggtttgccga atatcgagga cgaaagcaat agcgatacgg
    16501 cttatttgcg aaaccgcttc cggcaccgta ttttgcccga actttcggcg cagattcccc
    16561 atttcgggcg gcatctgttg aacaatgtcc gtgccttgca ggaggatttg gctttgttgg
    16621 acgaggtcgt cgttcaagac tgccgttggg tttgcggagc cggttatttc gatacggcgc
    16681 ggtggctgac gttttccccg cgccggaaaa cccatatttt gcggcatttt ttgaaggaaa
    16741 acggcattcc cgtgccgaat cagaatgccc ttgccgacat tgcccgggtt ttgacggagg
    16801 caaaaaccgg acgctggaac gtgcaaggct ttgaattgca tcattatgca ggcaggctgt
    16861 ttgtgttccg accggaaaaa acggataaac tgcggttttt gaaagacagg cagataagcg
    16921 gaaatttaag ggaaatattg gcggggcagg gatttgtttt aaaacgtcat ccgttcggac
    16981 ttcccgggca tcttttggag caggacggaa tcttgcggac ggttgcggca tcggacaggc
    17041 tggctgtcgg cggtatccat aaggatgtga agaaaatcct tcaggaaaag cgggttttgc
    17101 ccgcgctgcg cccgttttgg ccggtcgtcg ccgacaagga caaccgtccg ctggcgttgg
    17161 caaattacgg tacggatttt caaatctcgg tttcagacgg cattttgccc gtccatccgg
    17221 attttcccgt tttattttga tggaatcgga atcgccgtta cctattatat attcttgaaa
    17281 aggcggtaaa gtgaagcata tcagttcggc aaacaatgaa cacatcagac acctgcaccg
    17341 cctgttgtct caagggaagt tcagacggca atacgcccaa accgttttgg agggcgtgca
    17401 cctgcttcag gttttcctgc aatccggcgg gatgccggtc ggggtatata ttcccgaagc
    17461 gaaaatgccg tctgaagaag tccgtaaatt gacggcggtt ttgccggaag acggggtttt
    17521 ttccgtttca gacggcatat tgaagaaaat cagcagcctg acttgcgcgg atgatgtgct
    17581 tgcgctgatt gatattccgg atgcgggtgc tttgccggcc ggcggcgact gtgtggtttt
    17641 ggacggcgtg caagatccgg gcaatgtcgg cacggtgttg cggagcgcgg cggcggcagg
    17701 aatcggcgcg gtcgttttgg gcaaaggttg tgcggacgcg tggtcgccca aagtgctgcg
    17761 agccggaatg ggcgcgcatt tcttgtcgga gatttatccg caggcggatt tggaaatatg
    17821 gttggcgcgt tatgaagacc gtgtgtttgc caccgcgttg cgtgaggaaa aacaggcggt
    17881 tctgtataac gaagatttgc gcgaaccgac agcctgggtg tttggcaacg aaggcgcggg
    17941 tgtcggcaaa gcggttttag acagggcgga caagtgcgtc aggataccga tgcacgatgc
    18001 aaccgagtct ttaaatgtcg cgatggcggc gacaatctgc ctgtttgaac agatgcggca
    18061 gcggtcggcg tattgaggaa aagaaatgcc gtctgaaaaa atctattacg gcgtattgat
    18121 tttcttatgt atcgcttcta tgctgctgtc gccgtttttt tatgcgggtg ctttgaagcc
    18181 caagaaggcg gcattgcgga aggacgggca gtggaaactc atcttattgt ccaataccgt
    18241 ggcggcggcg gttttggctt gggtgtggtg gaaatggttt tgacagatat tgctcaaaat
    18301 cgtgctaatg gaatccgaac aaataaagaa ttttgtaaaa aatttgttaa atcaacgaat
    18361 taaagttttg tggaaaacaa aacagctcta agcaaatagg gcgtttgtcg gtaaatacgg
    18421 aagagttgcg gcattatcgg gcatctttaa caagtagtgc cgtcttggca ggcaatcggt
    18481 ttttatgggc agcttgcaaa atcgcggata taaaattgcg aatcggttaa agtgtgggga
    18541 cgctatgaaa aattgcgaat tttttatgac ccgacaaggg caatctatga tagcggtgca
    18601 gattatttaa ccagagaaaa acatagattc gtcgtaattg caaatagtgc ttgggggcta
    18661 ttgcttaatt tatcttgtta ttatgacaag gttttggaaa agcggaaaat accgttcggc
    18721 aaacaggaaa ttgatgacga tatggacaaa gtgtccgccc ataagcggaa gtttaaagat
    18781 atttctgaaa tcaaagtagg ggatggttgg gaatacccgt tcaattatga gcagggaatg
    18841 aaagaattag atgaagtgct attgaaatac attccctttt ttgaagaaga acgataaagg
    18901 aggttgatat gcgcgtatct aaaataattg gaagtatgtt gcttgttaca gcggttcaga
    18961 ccgtattttc ggcaaatgtt tacgcgtgcc gccataatgg taaaaccagt tacagccaaa
    19021 ctccgggaaa acattgtacc aacgcgggtt tggggcggga tcgggtgtac agttcggtta
    19081 gaccggcagt aaaagacagg gcggaagacg caggggtcgg cgattattcg gacacggtga
    19141 gggacgaaca cgtccaaaat ccgagagaga atacgcataa ggatgcttcg aataccggtg
    19201 caaagacgca ttgattgaaa ccgaatcagc catgacggcg ttgaataata gaatttgaac
    19261 gattagggaa ctctgatgaa acacatccac attatcggta tcggcggcac gtttatgggt
    19321 gggattgccg ccattgccaa agaagcaggg tttgaagtca gcggttgcga tgcgaagatg
    19381 tatccgccga tgagcaccca gctcgaagcc ttgggcatag gcgtacacga aggcttcgac
    19441 gcggcgcagt tggaggaatt taaagccgac gtttacgtca tcggcaatgt cgccaagcgc
    19501 gggatggatg tggttgaggc gattttgaac cgcgggctgc cttatatttc cggtccgcaa
    19561 tggctggctg aaaacgtgct gcaccatcat tgggtactcg gtgtggcggg gacgcacggc
    19621 aaaacgacca ccgcgtccat gctcgcatgg gtcttggaat atgccggact cgcaccgggc
    19681 ttccttatcg gcggcgtacc ggaaaacttc agcgtttccg cccgcctgcc gcaaacgccg
    19741 cgccaagacc cgaacagcca atcgccgttt ttcgtcattg aagccgacga atacgacacc
    19801 gcgtttttcg acaaacgctc caaattcgtg cattaccgtc cgcgtaccgc cgtgttgaac
    19861 aatctggaat tcgaccacgc cgacatcttc gccgatttgg gcgcgataca gacccagttc
    19921 caccacctcg tgcgtaccgt gccgtctgaa ggcctcatcg tctgcaacgg acggcagcaa
    19981 agcctgcaag acactttgga caaaggctgc tggacgccgg tggaaaaatt cggcacggaa
    20041 cacggctggc aggccggcga agccaatgcc gatggctcgt tcgacgtgtt gcttgacggc
    20101 aaaaaagccg gacacgtcgc ttggagtttg atgggcggac acaaccgcat gaacgcgctc
    20161 gccgtcatcg ccgccgcgcg tcatgccgga gtcgacattc agacggcctg cgaagccttg
    20221 agcacgttta aaaacgtcaa acgccgcatg gaaatcaaag gcacggtaaa cggcatcact
    20281 gtttacgacg acttcgccca ccatccgacc gccatcgaaa ccaccataga aggtctgcgt
    20341 cagcgcgtcg gaaacgcccg catcctcgcc gtcctcgagc cgcgttccaa cacgatgaag
    20401 ctgggcacga tgaagtccgc cctgcccgaa agcctcaaag aagccgacca agtgttctgc
    20461 tacgccggcg gtgtggactg gaacgtcgcc gaagccctcg cacctttggg cggcaggctg
    20521 cacgtcggca aggatttcga tgccttcgtt gccgaaattg tgaaaaacgc ccgaaccggc
    20581 gaccatattt tggtgatgag caacggcggt ttcggcggaa tacacaccaa actgctggac
    20641 gctttgagat agcccgggcg atgccgtctg aaagcccttc agacggcatc gtccggctgc
    20701 gcggcacaaa ggcggaaaaa ccgtttgccc cgtattttca aacgcgttac acttgccgcc
    20761 gctgttttca gccatttgat tacccgcaac cgccgtcatt gcgccggcgg tttgcctgtc
    20821 agcgtcattg cgccgctgta aatacgaaag aacacattat gaccgtatcc cccgtcgcct
    20881 tgcgccgtaa gaccgagtgc aagcctcatc ccaccgcgcg ctattggaaa aaatgcgatg
    20941 tcgaagccct gttcggactt cccttcctcg acctcattta ccaagccgcc gaaatccacc
    21001 gccaaaattt caacccgcgc gaaatccagc tttccacgct gttgtccatc aaaaccggcg
    21061 gctgtcccga agattgcgcc tactgtccgc aatcggcgca ccacaacacc aatctgggca
    21121 aagaacagat gatggatgtg gatgaaatcg tcgaaaaagc caaaatcgcc aaatcgcgcg
    21181 gcgcaagccg gttttgcatg ggcgcggcgt ggcgcggccc caaacccaaa gacgtggaga
    21241 cggtttccgc aatcatcaaa gccgtcaagg gcttgggtat ggaaacctgc ggcacgttcg
    21301 gtatgctcga agaaggtatg gcggaagact tgaaagaggc gggcttggat tattacaacc
    21361 acaacctcga caccgacccc gaccgctaca acgacatcat ccatacacgc cggcatgaag
    21421 accgtatgga caccttgggc aaagtccgca acgccggttt gaaagtctgc tgcggcggca
    21481 tcgtcgggat gaacgaaacc cgcgccgaac gcgcagggct gattgccagc ctcgccaacc
    21541 tcgacccgca gcccgaaagc gtgccgatta accggttggt caaagtggaa ggtacgccgc
    21601 ttgccgatgc cgaggatttg gactggacgg aatttgtccg caccatcgcc gtggcgcgga
    21661 ttacgatgcc gcaaagttat gtccgactgt cggcagggcg cagcaatatg ccggaagcga
    21721 tgcaggcgat gtgctttatg gcgggcgcga actcgatttt ttacggcgac aagctgctga
    21781 ccacgggcaa tccggatgaa gacggcgaca gaatcctgat ggaaaagctc aacctgtatc
    21841 ccttacagtt tgagctggaa ggcgaggtcg ccgaagtgga aaaagcctct gggattaaag
    21901 tggattattg acgattgcaa aaatgccgtc tgaaacccga aaaaaggctt tcagacgaca
    21961 tttgttcgga cggtatttcc aatatctttt taccggcgcg tgatgttgcc gtcgggcgag
    22021 acatccagcc cgttctcgtt ggggaagtcg ctgcggttca gataaataat ccgcccgata
    22081 acggtttttc agggtcgatt ttggggattt tatcgtcggc ttgggtaata gggatgatag
    22141 ttccggaaat aaatttaccc tgtttgttgg tgataatttt gaaaatcggc gcaatgccgc
    22201 tgatgccgga ggtgttgatt gcgccgtagg tggcaaagtt gccgccgctg taagagatga
    22261 agcggtcgcg gtaaagttcg acggcgcgtg taacgtgcgg cccctgcccg aatacgacat
    22321 ccgcgccgga atcgacggca agccgtgcaa actcgacgac gttgcccctg ttttccccat
    22381 agaagatttc ggtatcgaac ggcaggtgtt ccgcctgttt cccttccgcg ccgccgtgga
    22441 acattacaat gacgatgtcg gctttctgtt tggttttggt aatccgtttt ctaactttgg
    22501 cataatcgtt cagtttgacg gcggcaaggt tgggggcgaa ggagacgaag ccggatctta
    22561 cgccgttttt cttcaggatg gcggtttcaa acctgttttc gatgcccgaa tatttgatgt
    22621 tcaattcgtc aaggttcgcc ctttatgccg tttccgcacc gcaaaccgcc ggggtcaagc
    22681 cctcggcgca tcctgccgga acggaatccc cgtgctgccg attgacggtt caaaccccgc
    22741 gcccgtttca aataccggcg atgtggacgg acaggatgcg cctgacgaaa agacagccga
    22801 taccgtttcc attatcggcg tgggcgacat tatgctcggc agcaattatc cggtcgatta
    22861 cctgcccgat accaatattc tgaaaaacgt cgaatctgcc ttgcaagacg cggacattac
    22921 cgtcggcaac ctcgaaggca cgctgtttga cgaaggcggt acgccgaaaa aatgtgcaac
    22981 cccccaaaat atgctatgca ttccgaacgc cctccgcata cgggcaatac cttgccgacg
    23041 cgggattcga ctacctcagc ttcgccaaca accacagcaa cgacttcggc gcgcaaggca
    23101 tcacggcaac ggcggcgagc ggcagctctt ttacatactc gatcgcgcta aagccgctgc
    23161 cgataacgag gccaaaattg cggaaaatac cgccatcgcc cagataaatt tgtccatcat
    23221 cagaccttta ctgttcagac gagacagcat ttgccgcacg ttttggggct tatctttcga
    23281 tttgcgctat gtcgcgcacc gcgcctttgt cggcggaagt cgccatcgcg ccgtaagctc
    23341 ttaatgcggc ggagacgtag cggtcgcggt ttttaggctt ccatgctttg ctgccgcgcg
    23401 cttccatttc ggcacggcgt gcggcaagct cttcatcgga aatggcaagg tggatgctgc
    23461 ggttggggat gtcgatttcg acggtatcgc cttcgtgtac caaaccgatc gcgccacctt
    23521 ccgccgcttc gggcgaggcg tgtccgatgg acaaacctga tgtgccgccg gagaagcgtc
    23581 cgtcggttaa gagagcgcag gctttgccga ggcctttaga tttcaggtag gaagtcggat
    23641 acagcatttc ctgcatgccc gggccgcctt tcgggccttc gtagcggatg atgacgatgt
    23701 cgccggcgac gatttggttg cccaaaatgc cttctactgc gtcttcttgg ctttcaaaca
    23761 cgcgggcgcg gccggtgaat ttgaggatgc tctcgtccac gcctgcggtt tttaccacgc
    23821 agccgcgctc ggcgatgttg ccgaacaaga ccgccaaacc gccgtcttgc gagtaggcgt
    23881 gtgccacgtc gcggatacag cctttttcgc ggtcgaggtc gagggttttc cacatacggt
    23941 tttgcgagaa cgcttgggtg gtgcgtacgc cgccgggcgc ggctttgaag cgttcgatgg
    24001 cgcgggtgtt ttcagggttg gttacgtccc atttttcaat cgcgtctttc agcgtcggtg
    24061 cgtggatagt gtgcacgtcg gtgtgcagct tgcccgcttt gtccaattct ttcaggatgg
    24121 cgaaaatgcc gccggcgcgg tgcacgtctt ccatatagta gtcgtggttg ttgggtgcgg
    24181 ttttgcagat gcagggcaca acgcggctta agcggtcaat gtcggccatt ttgaaatcga
    24241 caccggcttc gttggcaacg gccaacaggt gcaaaatggt attggtgctg ccgcccatcg
    24301 caatatccat cgtcatagcg ttttcaaacg cttttttggt ggcaatgctg tgcggcagca
    24361 cggtttcgtc gttttgttcg taataacgtt tggtgatttc gacaatcata cgtcctgctt
    24421 cgaggaacaa ttctttacgg cctgcgtggg tcgccaaata cgaaccgttg ccgggtaggg
    24481 acagaccgag tgcttcggtc aggcagttca tcgaatttgc cgtaaacata cccgaacacg
    24541 aaccgcaggt cgggcaggcg ttttgttcga cttcctcgac ttgccggttg ctgacattgt
    24601 cgtccgccga ttcgatcatc gcgtcaatca agtccaaacg gcgttcgggt tggatgtttg
    24661 ccacgccgat aactttgccc gcttccatcg ggccaccgga aacgaagatg gtcgggatat
    24721 tcaggcgcat ggcggcaatc agcattcccg gggtgatttt gtcgcagttg gaaatgcaca
    24781 ccagcgcgtc ggcgcagtgg gcgttgacca tgtattcgat ggagtcggca atcaaatcgc
    24841 ggctgggcag ggaatacagc atgccgctgt gtcccatagc gatgccgtcg tcgatggcga
    24901 tggtgttgaa ttctttggcg atggcgccgg ctttttcgat ttcgcgggca accagctggc
    24961 ccatattgtg caggtggaca tgacctggca cgaattgggt gaacgagttg gcaacggcga
    25021 taatcggttt gccgaagtcg gtttccatca cgccggtggc gcgccacaat gcgcgcgcgc
    25081 ccgccatatt gcgaccgtgg gtggaggttt tggagcggta gtccggcata gtgtgtttcc
    25141 ttgtctgcta tgccgtctga acggcaaaag gctttcagac ggcatttttg ttgtgttttg
    25201 aaatgaaaaa aaaggtattt tataccaagt atcggaattt tgcgggattg aaacggcgtg
    25261 cggcaaaaaa gaaaatcccc gcaggaatgc ggggacgggt tcaggcgcgg gcaatcgcga
    25321 cggctttgga tgcgtcccaa aaatcaacgg gggcatttaa tacgggtttg acgatgcccg
    25381 tccgtatggc gaaatcgccg aaaccttcgc cgatattgcg ttctgccgcc catttgccga
    25441 tcaggtcgtc caattcggca aggatttcgg gcagggtgat gttttctttg taaaggcggg
    25501 ggatgcgtac gccttcacgg tcgccgccga tatggaggtt gtagcgtccg acggctttgc
    25561 cgaccagccc gatttccgcc aacattgccc gtccgcagcc gttggggcag ccggtaatgc
    25621 gggtaacgat atagtcgtcc gacgtgccgt gtttcgccat aatcttatcc agatcgtcga
    25681 tgaagtctgg cagcacgcgt tcggcttccg ccattgccaa ggggcaggtc ggaaaggaaa
    25741 cgcaggacat cgcattttcg cgcagcttgc tgacatcgtt gcggattaat ccgtatgttc
    25801 gggcaagttc ttcgattttt gctttgtctg cttcggcaac atttgccacg atgaggtttt
    25861 ggtttgcggt aatgcggaaa tcgcctttgt ggattttggc gatttccaac acgccggtca
    25921 gaagctgttt cccgccttcg tcaaccaaac gcccgctttc gatgaaaagg gtcaaatgcc
    25981 agttgccgtc tatgcctttc acccagccga tgcggtcgcc gcgcccggta aatttgaacg
    26041 ggcgtatggg ttcgaacggc atacccatac ggcgttcgac ttccgcgcgg aagttgtcca
    26101 agcccatatt ttgaatggtg tagcgggtgc gggcgttttt gcggtcgctg cggttgccga
    26161 agtcgcgctg tgtggttacc accgcttcgg cggccttcag cgcgtgttcc ggaggtacga
    26221 aacccagttc cagtgaaatg ttcggatagg ttttggtgtt gccgtgttcc attgaaagcc
    26281 caccgcctgc caaaacatta aaaccggcaa gctgtccgcc gccgtctgaa atggcgacaa
    26341 aatccaagtc gttgccgtag cagtccacat catttaaggg cgggatgacg actgcggttt
    26401 tgaatttgcg cggcagatag gttttgccca aaatcggctc gtcttcttga aggaagtcgt
    26461 cggaactttg aacttttttg ccgtccaccc aaacatccag ataaccgcgc gtgcgcggca
    26521 gcaagtgttc ggaaatcttt ttcgcgtatt cgtaagcctg ttggtggagt gccgactcga
    26581 tgggattgga ggtgcaaagc acgttgcggt tcatatccgc cgccgtggcg atggaatcca
    26641 aacccagttt gtgcaagagg cggtgcatcg tctgcaactt ggttttcggc acgccgtgaa
    26701 attggaaggt ttgccggttg gtcagcctga tggatcggta ataactgttt tcgcgggcga
    26761 atttgtccaa ttctatccat tgggacggct tgatgatccc acccggcagc cggcagcgca
    26821 aaagcataaa tttcaagggt tcgagttttg cctcggcgcg ttcggcgcgg atatcgcggt
    26881 catcctgctc atacatgccg tggaagcgga tgagttggaa attgtcgccc ttgaagccgc
    26941 ccgtgagctg gtctttcaaa tcgtccaaaa tcgtgccgcg taaaaaattg ctttcggttt
    27001 tcaggcgttc gttgttggat agcggttttt cttgccactc caaacctttt gtcttggtct
    27061 gtacggtcat tttgtgttcc ttccgatttc atttaatcaa taaacatcac gctgatagcg
    27121 tttttcttca cgcagcgtat ttaaatattc ttctgcgtcg tcccggttta aatgtcctgc
    27181 ttgaataatc acatccaata aggcggcttc gacatctttt gccatttttg ccgcatcgcc
    27241 gcacacataa acatatgcgc cctcctgcaa ccattgccaa agctctgccg cctgttcgcg
    27301 gattttgtgc tgcacataga ttttttcttc ctgatcgcgg gaccaggcga aatcgtattt
    27361 atgcaggaaa ccctctttgg caaactgctg ccattcggtc tgatagagga agtcggcggc
    27421 aaaatgcgga ttgccgaaaa tcagccagtt tttgccttcc gcattttctg cggcacgttg
    27481 ttggacgaaa gcgcggaacg gtgcgacgcc ggtgcccgag ccgatcatca caatcggctt
    27541 gcggctgtct tcgggcagtc tgaagccgtc gttgcgctcc acaaatacac gcaccgtgcc
    27601 gtcttcttcg acgcaatcgg caagaaaacc ggatgcgccg cccgttctgg cgcggccttc
    27661 gtgttcaaaa cgaaccacgc cgacagttaa atgcacttca tcgcccactt ccgcctgtgc
    27721 tgaagaaatc gaatacaaac ggggtgcaag cggacgcagt aaacggatga attgttctgc
    27781 cgtcaggctt gccgggaagc ggtgcagcac atcgacaata ggcgtgtttt gcacgaaatc
    27841 ctgcaaaacg gcgttatcgg caatgatttt atcgagttct tcataatggg cgaacgcggc
    27901 atagcctttg acgaaagccg gagtgttttg cgtgagttcg aaatgagatg aaagtgcgcg
    27961 cgcaaccggc atcatctttc cgcctgcctg tatttccgtt gccggatcga tgccgagcag
    28021 gtctaggatt tccccgacca gtgccggatt gttgtcaaac caaacgccga gcgcgtcgcc
    28081 tgcctgatag cttaaatccg aaccgctcaa atcaagttcg atgtggcgca cgtctttatc
    28141 ggattggcgg gcggtgattt tctgattggc cagcagggcg gcgggaaagg ggtctgcctt
    28201 gcagtacctg ctctccggta ccgtctgaag gtcggcgggg ggcattgcct gtggcgcggg
    28261 tgttgcccgg ttttttgcgg cttcttcttt taagagtgcg gcgatattgt ctgtccaggc
    28321 gtttgcagag gcggtaaagt ccaaatccgc atcaacgcgt tcgagcaggc gtttcgcccc
    28381 caattcttca aaacgccggt cgaaatcttt acctgcctga cagaaattcg gataggagct
    28441 gtcgcccaag cccagtacgg caaattggag tttgtccaat ttcggggctt ttttgccgtt
    28501 cagcagtttg tgcagcacga cggcttcttc cggcggttcg ccttcgccct gggtggacgt
    28561 aaccagcagc aggcggcgtt cgtctgcgat gtttttcgcc ttgtagtctt tcagttcggc
    28621 gagcctgact tgtatgccgg cggctttcag gctgtccgcc gctttgtcgg caacggattt
    28681 cgcattgccg gtttgcgagg cggaaaggac ggtaacggaa aagggttctg ccgccggcaa
    28741 tgctgtctga agcgcgggca gccctgcgga tgccccgttt cctgcttttg cccaagcata
    28801 gccggacagc cacgcccatt gtgccgcgtc cagccccgac aggagctgcg tgatttcggg
    28861 cggcagaggc ggtaatggcg gatttgtgtt ctgcatatcg tgttcactca taaaatcata
    28921 cctgccgcaa cagtgccgta tgtcgattcg tctatcagga taaacgaacc ggcggcggtg
    28981 ttttccgcat aaggcgttgc cgtaacgggt ttttgaaggt tgatgcggac tttggcgatg
    29041 tcgttcatct tcaaggattc cgcgccggcc tcttgttcca gcgtgcggac atccaaaacg
    29101 ctttcaattt ccccgacttt tgccggcacg gtttgcgtgc cgtgcttgag caggtatttg
    29161 cgcgcggtgt tgagcggacg ttcgtcaaac cagcaaagcg tggcttccag atgtttttgc
    29221 ggggcgagcg gggaattttt atcgacaaaa aggtcgccgc gcgaaacatc gatgtcgcgg
    29281 tccagccgga gggttgccgc ctcgccggca aaagcctgcg ccacttcccc tttcggcgtg
    29341 atgatttcgg acacttcggc ggtcagcccg ttcggttcga tgcggacggt ttgcccgacg
    29401 gcgaccgaac cgcgttcgat gcgcccctga tagcctcgga aatcatcggc cttgtcggca
    29461 tcttggcgga cgaccagttg cacggggaaa taaaaatcgt cggcggtgcg gctgacttcg
    29521 tccgcccccg gcagggtttc caaaatggac aataagggtt cgcctttata ccaaggcata
    29581 ttgccgccgg ggtaaacaat gttgtcgccc aagagtgcgg acaccggtac gaaatgcgcg
    29641 tctttcaaac cgagctgttc ggcaagtcgg cggtatgcct ccacaatggc gttgaatttg
    29701 tcttcgctgt aatccagcag gtccattttg ttgaccgcca ccacaatatg cgggcagttg
    29761 agttggcgga ggatggcgga atggcgtttg gtctgcggca gaagctgtaa gggctgcgcg
    29821 ccgaaatcca gttgggatgc gtcaaccagt acgactgccg ccgaagcggt gcttgcgccc
    29881 gtaaccatat tgcgcgtgta ttgttcgtgc cccggcgtgt cggcgatgat gaatttccgt
    29941 ttcgccgtgg aaaaatagcg gtatgccaca tcgatcgtaa tgccctgttc gcgttcggct
    30001 tccagtccgt cggtcaggat ggagaagtct atggtttctt tcaaaccgtt gcttttgccg
    30061 gattccaagg ttttgatttg gtcggacagc agggctttgc tgtcgtagag cagtcgtccg
    30121 attagggtgc ttttgccgtc atcgacgctg ccggcggtaa tgaagcggag cggggtttgg
    30181 tgttgtgccg tcatattttc ttcctcatat ctgcttaaag ggtttttgaa atttagaaat
    30241 agccttcttt tttgcgtttt tccattgccg cctcgcttgc ctgatcgtcc agccgggtcg
    30301 cgctgcgttc ggaaatgtcg gcaaccgccg tttccctgat aatctccgtc ggcgtggacg
    30361 cggtgctttc taccgggcag gtgcagctga tgtcgccgac ggtgcggaag cggacatcaa
    30421 ggatttcgga ggtttcagac ggcattttcg gcgtaagcgg cgtaacgggg accagcagcc
    30481 ccctgcgtct gaccacttcg cgcctgtggc tgtaataaat cggcggcagt tcgaggtttt
    30541 cgcgggcgat gtattgccag atgtcgagtt ccgtccagtt ggaaatcggg aagacgcgca
    30601 tattttcgcc tttgtgcagc ctggtgttgt acagcgacca cagctcgggg cgttgcgcct
    30661 tcggattcca ttgtccgaac tcgtcgcgga acgagaaaat ccgttctttg gcgcgggctt
    30721 tttcttcgtc gcgccgcgcg ccgcccatca gcgcgtcaaa gccgtttgcc tcgatggttt
    30781 ccaacagcgt aaccgcctgc gccgcattgc gcgaatcggt ttctttgcgt aaaactactg
    30841 tgcctttggc gatggagtct tccacgcgcc ccactatcag gcgggcattg agttttgccg
    30901 cctgcgcgtc gcggaaggca atcacttcgg ggtagttgtg ccccgtgtcg atatgcacca
    30961 gcgggaaggg cagttttacc ggcctgctgc ccagccggaa ggctttgcag gcgagggcga
    31021 gcaggaccac ggaatctttg ccgccggaaa agagcagggc ggggttttcg cattctgccg
    31081 ccacttcgcg gataatgtgg atggattcgg attccaacca gtcgagttgg gcgttgttcg
    31141 gttcggtttt cgtcatacca tattccttat ttcttctgtc tgatatttat gaattatttg
    31201 tgcagcccgc attctttgct gtttctgcct tcccaccacc accgcccggc gcggatgtct
    31261 tcgcccgcct tgacggggcg ggtgcagggg tcgcagccta tgctgggaaa tccttgccgg
    31321 tacaaatcgt tgtaaggcac attgttggcg aggatgtatg cccacacgtc gtgttccgac
    31381 cagtcgaaaa tcgggttgta tttgccgatg tcccgtccgg catcgtattc ggcaaacggc
    31441 agttccgtgc gtgtggcgga ctgttcgcgg cgttgcccgg taagccaggc gtccgcgcct
    31501 gcaatggcgc ggttgagcgg ttcgattttt cggatgcggc agcattcgcg gcgcgcttca
    31561 acgctgtcgt aaaaggcaaa cctgcctttg ctttccacat aacggtcggc atcttctcga
    31621 accggccgga aacgctttat ccgcaaatgg ggatatgcgc gtccgagtct gtccagcagg
    31681 tttagggttt ccgtgtggag cagccccgta tccaaggtaa aaatgccgat attgaggttt
    31741 tcgccggcga taaggtcggt aatcaccata tcttctgccg caaggctgct ggcaaaccgt
    31801 gcatcccggt ggctgccgac aatccggtgc aggcgttgtt tgagggtttc cgttttttcc
    31861 gcaagggcgg tttcgccgcc ggatccgata tgcggtatct gccacagggc gggtttgaac
    31921 agtgtcgttt ccatttttcc cgccttatgc cgcccgttgt ccggcattca gtccgcccaa
    31981 tgcgggatac gtctgcccga cccggttttc tccttcgccg ttttcaccga accaggcgag
    32041 tttttcgtgc agccccacca cttcgcctat gacaatcaat gccggattcg gcgcggtttc
    32101 ggcgagttcg gcaaggttgg cgagcgtgcc ggttgcggtt ttttgagccg gcagcgtgcc
    32161 ttggctgatg acggctgctg gcgtgtcggg cgagcgtccg tgctgttgca gccgttcggc
    32221 aatcagggcg gctttgagcg cacccatata aatcaccaag gtctggcggc tgcgggcgag
    32281 ggtctgccat tcgatgtcgg gcgcatccgc cttgcggtgg ccggttacga aaaccgcact
    32341 ttgggcataa tcgcggtgcg tgagcgggat gccggcatag gcggtcgcgc cgacggcggc
    32401 ggtaatgccg gggacgaccg aaaacgggat ctgatggcgt gccaaggttt ccaattcttc
    32461 gccgccgcgt ccgaacacga aagggtctcc gcctttcaaa cgcaccacgc gcctgccttc
    32521 gcgggccagc ctgaccataa gcgcattggt gtcctcttgc ggggtgcggt cgccccgggc
    32581 gcgcttgccg acaaaaatcc gttccgcatc gcggcggacg agggacagta tgccgtctga
    32641 aaccagcgcg tcgtaaagca ccacgtctgc ctgctggatt tcctgcagcc ctttgagcgt
    32701 cagcagcccc gcatcgccgg gacccgcgcc gaccagcgag acggagccgc cttgatcatt
    32761 ttgacgactt tgttccaatt ggcctgccaa ttcccgttcg gcaagggtgt tttgccggtt
    32821 tttgacgagg gcggcgaaac gtccgttaaa ctgcttttcc caaaagcggc ggcgttcggt
    32881 aacggatttc agtttgccct tgacggcatc gcgccacctt cctgaaattt ccgccatatc
    32941 gcccaaagac ggcggcagca gggcttccag cctttcacgc agcagtcggg cgaggacggg
    33001 cgcgctgccg gagctggaaa cggcaatctg aaccgggttg cggtcgataa ccgacgggaa
    33061 gatgaagctg caatggtcgc ggtcgtccac cacgttgacc ggcttttggc agctttcggc
    33121 aagatggaaa acgcgccggt tgagggcttg gtcgctgctt gccgcaatga tgaggaaaac
    33181 cgtgcggatg tgttcggcac gaaattcttc ggcaagccac aggattttgt tttccgccgc
    33241 caacgcggag agttcggcat tcaggtgttt tgcggcaacc ctgacctctg cgcccgcctt
    33301 cagcagcagg ctgattttgc gtgcggcgac cgcgccgccg cctacgacca atacggggcg
    33361 gccggcgagg ttggcgaaaa tagggaaata attcactggc tgactccttt gctgtttgcc
    33421 cgcaccttgt ttccgatacg gtgcgtcgcg gcatttttgt cggaatgcgg gtcattttag
    33481 acaaaaggat tttcccggtt aaataataaa aaggcatttg ttagaagctg aaagctatat
    33541 gagggcggct gcggatacgg cggttttccg ttttatagtg gattaacaaa aaccagtacg
    33601 gcgttgcctc gccttagctc aaagagaacg attctctaag gtgctgaagc actaagtaaa
    33661 tcggttctgt actatccgta ctgtctgcgg cttcgtctcc ttgtcctgat ttttgttaat
    33721 ccactataaa acggtttggg acggaaaaac ggcctgaagc cgtttcgggc attcagaccg
    33781 tttgcgcgga gaggggatgc cgtccgaagg gcgaaaaggg cttcagacgg cattgatgtc
    33841 gggtttcagg acaggagcag gatggcggct gcggcaagcg cggcaaccga taatgcggcg
    33901 gcaagcgcgg ttttaccggc aaagcggatt gaggttttgc cttcgatgta tttgaagccg
    33961 gttatcatcg ggaggacgag gtttttcttt ttgaacacgc ggtatgcggc gacggcggcg
    34021 atatgaatgg cggaaaaaac ggcgagcagg ttgaaaaagt tgaggtggat tttccgcata
    34081 aggctgcctg tatgttcgga aaccaaatgg ttgaggtagc cgttggtgct gaaggtgttt
    34141 tcatcggcgg caaaaagccc cgtgccgatt tgaaatgaga cggcggccaa aagcgcgacg
    34201 accatcagtg cgcccaaggg gttgtgtccg ggctggatat gttcgggaat accgtttttc
    34261 agataatccc tgatacccga ccatccgcgg acgaaacggg agaaacgggc ggtatcgctg
    34321 ccccaaatgc cccagcagag gcggaatacg agcaggaaaa ggataaacag cccgacgcgc
    34381 gtgtgccatt gaagcatatc gccgccggct tttgcgctat accacataaa gggcaaggac
    34441 gcggcaagca gccagtggaa aaggcgggtg gggaggtccc agactttgct tttgtttttc
    34501 ataatcggtt tccggcggta gaatcggttt gttttcgagc cttaatttta accgattgga
    34561 ggggaaatgt ttcccgtttt ccatctttca ggcgaaagcc gccgccggat gcttcaggcg
    34621 gcattgcgtt ttccctatgt tttcaaagcc cgtgcggaag attcgcacaa agggactttc
    34681 ggcacgctcg ccgtagtcgg cggatcggca gggatgagcg gtgcgcccgt attggcggca
    34741 tcggcggcga tgtatctcgg ctgcggcaag gtgtgggcgg gtttcaatca ggatgcgctt
    34801 ccgtttgccg tcattgccgg tttccccgaa attatgttgg acacggcaga cggtttgacc
    34861 aagcgtcaag gcataaacgc ctgggttgtc ggttgcggct tgggtacgga taaggcggcg
    34921 gtcggaacgc ttgccggaat tttgacggaa cacacggaca agcccgtcct tttggatgcg
    34981 gacgcgctga acatattatc aaccgatgcc gaaacccgaa atctggcacg cgggtgtaaa
    35041 aacctgattt taacgccaca ccccgccgaa gccgcgcgcc tgcttggaac gacggttgca
    35101 caggttcagg cggatcggac ggcggcagtg aggaagataa gggcaatttt cggcgcaacc
    35161 gtggttttaa aggggcacaa aacattggtt gcctcacccg atacggaaat ctatgtcaac
    35221 gaaagcggca acgcgggatt ggcaacggcg ggcagtggcg acgtattggg cggcatcatc
    35281 ggcagtctgc tcgcacaggg cgtgccggtt tttgaagccg cctgcgcggg cgcgtggctg
    35341 cacggcgcgg cggcggatgt cataaaagaa tcggcaggca ttgcggcagg gctgttggct
    35401 ggcgaaatcg ccccggcggc aaggtggctg cgcaaccgga taactgaaag tatgtaagaa
    35461 gatatagtgg attaacaaaa accagtacat cgttgcctcg ccttagctca aagagaacga
    35521 ttctctaagg tgctgaagca ccaagtgaat cggttccgta ctatttgtac tgtctgcggc
    35581 ttcgtcgcct tgtcctgatt tttgttaatc cactataccg tctgaaaggc aagggcttca
    35641 gacggcatct tcatttccca aatactgtcc ggtaaagcgt ggtataatgc gcagttatct
    35701 cttacagttt ttgaaaaaca ttaattatga aacaaatccg caacatcgcc atcatcgccc
    35761 acgtcgacca cggcaaaacc acattggtcg accaactgct gcgccaatcc ggcacattcc
    35821 gcgccaacca gcaggttgac gagcgcgtga tggacagcaa cgacctcgaa aaagaacgcg
    35881 gcatcaccat cctcgccaaa aacaccgcca tcgattacga aggctaccac atcaatatcg
    35941 tcgacacgcc gggacacgcc gacttcggcg gcgaagtgga gcgcgttttg gggatggtgg
    36001 actgcgtcgt cttgttggtg gacgcgcagg aaggcccgat gccgcaaacc cgtttcgtga
    36061 ccaaaaaagc cttggctttg gggctgaaac cgattgtcgt catcaataaa atcgacaaac
    36121 cgtccgcccg tccgagctgg gtcatcgacc aaactttcga gctgttcgac aacttgggcg
    36181 cgaccgacga gcagttggat ttcccgattg tttatgcttc cggtctgtcc ggtttcgcca
    36241 aattggaaga aaccgacgag agcaacgaca tgcgtccgct gttcgatact atcttaaaat
    36301 atacgcctgc accgagcggc agcgcggacg aaacgctgca actgcaaatt tcccaactcg
    36361 actacgacaa ctacaccggc cgcctcggta tcggtcgtat cttgaacgga cgtatcaagc
    36421 ccggtcaagt tgttgccgtc atgaaccacg atcaacaaat cgcccaaggc cgcatcaacc
    36481 agcttttggg tttcaaaggt ttagaacgcg tgccgcttga agaagccgaa gccggcgaca
    36541 tcgtgattat ttccggtatt gaagacatcg gcatcggcgt aaccatcacc gacaaagaca
    36601 accccaaagg cctgccgatg ttgagcgtgg acgaaccgac gctgaccatg gactttatgg
    36661 ttaacaccag cccgttggcg ggtacggaag gcaaattcgt aaccagccgc caaatccgcg
    36721 accgcctgca aaaagaattg ctgaccaacg tcgccctgcg cgtggaagac accgccgatg
    36781 ccgacgtgtt ccgcgtatcc ggacgcggcg agctgcacct gaccattttg ttggaaaata
    36841 tgcgccgcga aggctacgaa ctcgccgtcg gcaaaccgcg cgtcgtgtac cgcgacatcg
    36901 acggtcaaaa atgcgaacct tatgaaaacc tgactgtgga cgtacccgac gacaaccaag
    36961 gcgcggtaat ggaagaactc ggccgccgcc gtggcgaact gactaatatg gaaagcgatg
    37021 gcaacggacg cacccgcctc gaataccata ttccagcgcg cggcttgatc ggtttccaag
    37081 gcgaattcat gaccctgacg cgcggtgtcg ggctgatgag ccacgtgttc gacgattacg
    37141 cgcccgtcaa acccgatatg cccggccgcc acaacggcgt gctggtgtcc caagagcagg
    37201 gcgaggcggt cgcttacgcc ttgtggaatc ttgaagaccg cggccgtatg ttcgtatcac
    37261 ccaacgacaa aatctacgaa ggtatgatta tcggcatcca cagccgcgac aacgatttgg
    37321 tggtcaaccc gctcaaaggc aaaaaactta ccaacatccg cgccagcggc accgacgaag
    37381 ccgtgcgcct gaccacgccg atcaagctga cgctggaagg tgcggttgag tttatcgacg
    37441 atgacgaact cgttgaaatc acgccgcaat ccatccgtct gcgcaagcgt tacttgagcg
    37501 aattggaacg ccgccgccac tttaaaaagc tggattgatg tttactggat taatgtttaa
    37561 atgatacgcg atgccgtctg aaaaatttca gacggcattt tttattcgga cgggctttgc
    37621 ggcttcttga agctgtttca gacggcgttt ttcctaccca atcaagaaac tgccgccatt
    37681 tttccagcgg tatatcgccc cgtcgcgttt cggtatcggg ttcggcttcc cggcagcatg
    37741 tcgaacaatg ccgtttgaag gaatacgcct tttgagtcct tacaagctta ggaagaggat
    37801 atagtggatt aacaaaaatc aggacaaggc gacgaagccg cagacagtac agatagtacg
    37861 gaaccgattc acttggtgct tcagcacctt agagaatcgt tctctttgag ctaaggcgag
    37921 gcaacgccgt actggttttt gttaatccac tataaaatat accgcaaaac ataccataaa
    37981 aaaacggtaa cggatagttg taagcggttg atgacgatta tagacaataa cgggttttcc
    38041 caatgaaatt attgtttgaa taataaaaaa tcccaaaccg taaaagtttg ggatttgtat
    38101 ttggcagaga ggaagggatt cgaaccctcg atacgctatt cacgtataca cgctttccag
    38161 gcgtgcgact taaaccactc atccacctct ctaatggcgg aaattatccc aatcgggata
    38221 atttattatt tggtgcccgg gagaagactc gaacttccac acccatgagg ataccagcac
    38281 ctgaagctgg cgcgtctacc aattccgcca cccgggcaat ctaaatattg aaataaagca
    38341 aagcatttga tttggtgccc gggagaagac tcgaacttcc acacccgtga ggatactagc
    38401 acctgaagct agcgcgtcta ccaattccgc catccgggct ttgctttatt tgctgttttg
    38461 cggtacagtg tcctgccgca aagaagtcgc tattatatag ttcataaaga gaatgtcaac
    38521 agtccaaatg aataaaaata ttaaatcttt aaatttacgg gaaaaagacc cgtttttaag
    38581 tcgtgaaaaa cagcgttatg aacatccttt gcccagtcgg gaatggataa tcgaattgtt
    38641 ggagcgcaaa ggtgtgcctt caaaaatcga atcgcttgcg cgcgagctgt cgattacgga
    38701 agacgagtat gtctttttcg aacgccgtct gaaggcgatg gcgcgggacg gtcaggtttt
    38761 aatcaaccgt cggggcgcgg tttgcgcggc ggacaaattg gatttggtca aatgccgcgt
    38821 cgaggcgcat aaggacggtt tcggttttgc cgtgccgctc acgcccgcca aagacggtga
    38881 ttttgttttg tatgaacgcc agatgcgcgg cattatgcac ggcgatattg tcactgttcg
    38941 tcctgccggc atcgaccgta ggggccgccg cgaagggaca gttctggata ttgtcgaacg
    39001 cgcgcaaagc aaagtggtcg gccgtttcta tatggatagg ggcgtggcga ttttggagcc
    39061 ggaagacaag cgtctgaacc aaagcatcgt attggaaccg gacggcgtgg cgcgtttcaa
    39121 acctgaatcc ggtcaggtca tcgtcggcga aattgaggtt tatcctgagc aaaaccggca
    39181 ggcagtggca aaaatcatcg aagttttggg cgattatgcc gacagcggca tggagattga
    39241 aattgccgtg cgcaagcatc atttgccgca ccaattcagt gaagcgtgtg ccaaagccgt
    39301 gaaaaaaatt cccgaccatg tacgcaaaag cgatttgaaa ggccgcgtcg atttgcgcga
    39361 cctgcctttg gtaacgattg acggcgaaac ggcgcgcgat tttgacgatg cggtgtttgc
    39421 cgaaaaaatc ggacgcaatt accgtctggt cgtggcgatt gccgatgtca gccattatgt
    39481 ccgccccgat gacgctatcg acacggacgc tcaggaacgc agcaccagtg tttacttccc
    39541 gcgccgcgtg attcccatgt tgccggaaaa cctgtccaac ggcatctgct cgctcaatcc
    39601 taatgtcgag cgtttgtgta tggtgtgcga tatggtcatc acttacgcgg gcaatattaa
    39661 agaataccgc ttctaccccg ccgtgatgcg ctctcatgcc cgcctgacct acaaccaagt
    39721 ttggaaatgg ctttcaggcg gcatcgggca tccgttcaaa acacaaatcg acacgcttta
    39781 caaactcttc aaaatccttc agaaaaagcg tttcgaacgc ggggcggtgg agtttgacag
    39841 catcgaaacc caaatgcttt tcgacgacaa cggtaaaatt gaaaaaatcg tccccgttgt
    39901 ccgcaacgat gcccacaagc tgattgaaga atgtatgctg gcggcgaatg tttgcgcggc
    39961 ggattttctg ttgaaaaaca agcatacggc tttgttccgc aaccatttgg gccccacgcc
    40021 cgaaaaactc gccaccctgc gcgagcagct cggtctgttg gggcttcaac ttggcggcgg
    40081 cgacaacccg tcgccgaaag actatgccgc gcttgtcgaa caattcaaag gcagacctga
    40141 tgccgaattg ctgcaagtca tgatgttgcg ctccatgcaa caggcggttt acgaaccgca
    40201 ttgcgacgga cactttggtc ttgcctacga agcatacgcc cacttcacct cgcccatccg
    40261 ccgctatccc gacctgaccg tacaccgcgc catcaaagcc gtgttgaatc agcaaaccta
    40321 cacgccaaaa aaaagctggc aggctttggg cgtgcatacc tcgttctgtg agcgccgtgc
    40381 cgacgacgcc agccgcgacg tggaaaactg gctgaaaacc tattatatgc gcgataaggt
    40441 cggcgaagta ttcgaaggta aaatctccgg catgaccagt tttggtatct ttgtaacact
    40501 ggacggcatc cacattgacg gcttggtgca tatcagcgat ttgggcgaag actatttcaa
    40561 cttccgcccc gaaatcatgg caatcgaagg cgaacgcagc ggcatccgtt tcaacatggg
    40621 ggacagggtt gccgtccggg tcgcccgtgc cgatttggat gacggaaaaa tcgattttgt
    40681 cctgattgcc ggggggagcg gcagggggcg gaaagttaaa tcatccgcgt ctgccaaacc
    40741 ggcagggacg gcggggaaag ggaagccgaa aaccgccgcc gagaaaaaaa cagcccgagg
    40801 cggcaaagta aggggaaggg gcgcgtctgc cgccgcagaa tcggggaaaa aggcaaagaa
    40861 accggttccg attaaggtaa aaaaacggaa aggcaaatca taatgctgac ggg
//
LOCUS       DAXISH010000010        40011 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.010, whole genome shotgun sequence.
ACCESSION   DAXISH010000010 DAXISH010000000
VERSION     DAXISH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 40011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40011
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.010"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(175..867)
                     /locus_tag="ACFOV4_000548"
     CDS             complement(175..867)
                     /locus_tag="ACFOV4_000548"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HFC7618622.1"
                     /translation="MKRFTYTLSDGLCIEIELKRSAKKNLILRPVNMQTVSINVPPFF
                     QDHALANWLAANETILRNTLAKTPVHPVSHPNLPEWIWYRGIKTKLDTHSQSHIRITS
                     SEILLPRKETAAQIDHLRRLLNERAREYLLPRLEKHAAETGLTPTATDLSNAKTFWGV
                     CRPHTGIRLNWRLIGAPKYVADYVCIHELCHLRHPDHSPRFWHLVNTLTPHTDNAKSW
                     LKAHGRELFVLG"
     gene            complement(975..2168)
                     /locus_tag="ACFOV4_000549"
     CDS             complement(975..2168)
                     /locus_tag="ACFOV4_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HFC7618623.1"
                     /translation="MSDQKNRRNALIGAAFLMATSAIGPGFLTQTATFTQALAASFGF
                     VILLSILLDIGAQLNIWRIVAVSEKQAQDIANQVLPGAGYFLAVLIVMGGLAFNIGNV
                     GGAGLGLNLLTGLSPETGAVISGVIAIGVFLFKEAGKVMDKFAQVMGFVMIALTVYVA
                     WQANPPLADAAVHTFMPEKLDAMAIVTLVGGTVGGYITFAGAHRLLDAGIKGKSALPE
                     VSQSSVRAILIASIMRIVLFLAVLGVVSQGVQLNPDNPASTPFEYAAGYIGLLIFGVV
                     IWAASITSVIGAAYTSVSFFSGLSPSIERNKNKWIIAFIAVSTAVFSTIGKPAQVLVF
                     VGALNGLILPISLGLILIAAYKTKIVGDYKHPLWLTVSGVIVVGLMAVLSAITISKYI
                     GGLFG"
     gene            complement(2297..3034)
                     /gene="pxpA"
                     /locus_tag="ACFOV4_000550"
     CDS             complement(2297..3034)
                     /gene="pxpA"
                     /locus_tag="ACFOV4_000550"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HFC7618624.1"
                     /translation="MKQVDLNADLAEGCGSDEALLQLITSANIACAQHAGSIADIRAA
                     LAYAQQNGVRIGAHPGYPDRENFGRTEMNLSEADLRACLNYQLGALQALCRDQGLEMA
                     YVKPHGAMYNQAAKNRALADTVARIVADFDPKLKLMALSGSLLLEAGKAAGLGVISEV
                     FADRRYMPDGTLVPRSRPDAQVDSDEEAIAQVLQMVRDGRVKAVNGSLVAVQADSICL
                     HGDGPHAVVFAEKIRQELLAAGIKVSA"
     gene            complement(3021..3950)
                     /locus_tag="ACFOV4_000551"
     CDS             complement(3021..3950)
                     /locus_tag="ACFOV4_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HFC7618625.1"
                     /translation="MIHVSAVQAPAHIQDTGRYGHRRYGIGHAGAMDTVALAAGNILL
                     GNDEGTAAIEIALGGIMLVFERDTPFCLTGAVYQAELDGEPVYSYWRYTARKGQTLKM
                     VRAVQGMYGYVCVAGGFDVPEVMGSRSTDLKAGFGGHQGRMLQKGDYLPIGKGAQELS
                     KVGIAPIPFTDTVHLVPSSEYAAFSEKGRLNLERETWTLQSDSNRMGYRFDGQPLTLS
                     QPLEMLSHAVQAGTVQVPPGGKPIILLADAQTTGGYPKIATVAAADLGRLAQVRFGSK
                     VKFKIIGLKEATALRRKNQAYLNQIRRITHEAG"
     gene            complement(3947..4594)
                     /gene="pxpB"
                     /locus_tag="ACFOV4_000552"
     CDS             complement(3947..4594)
                     /gene="pxpB"
                     /locus_tag="ACFOV4_000552"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HFC7618626.1"
                     /translation="MRIEITPISESALVCRLNAPSELGKQQKLWAFAAALGQHDRIEE
                     VVVGMNNLTVFTRFDTDLATLADELQYVWEHTAVTDHQGKLVEIPVCYGGEYGPDLAE
                     VAAFHQTVISEIVRRHTAQTYTVFMMGFQPGFPYLGGLPEALHTPRRAVPRTSVPAGS
                     VGIGGSQTGVYPFASPGGWQIIGRTELPLFRADLNPPTLLAAGDQVRFVAERIEP"
     gene            4778..6985
                     /gene="uvrD"
                     /locus_tag="ACFOV4_000553"
     CDS             4778..6985
                     /gene="uvrD"
                     /locus_tag="ACFOV4_000553"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HFC7618627.1"
                     /translation="MFPDQSAPNLLQGLNPEQLSAVTWPPQSALVLAGAGSGKTRVLT
                     TRIAWLLQTGQASVHSIMAVTFTNKAAKEMQTRLGAMIPINVRAMWLGTFHGLCHRFL
                     RLHHRDAGLPSSFQILDGGDQLSLIKRLLKSLNIAEEIIAPRSLQGFINAQKESGLRA
                     SVLSAPDPHTSRMIECYAEYDKICQREGVVDFAELMLRSYEMLQSNEILRQHYQNRFN
                     HILVDEFQDTNKLQYAWLKLMAGGNAAVFAVGDDDQSIYRFRGANVGNMTALMEEFHI
                     DAPVKLEQNYRSVGNILAAANAVIENNDERLGKNLRTDAEAGDKIRYYSAFTDLEEAR
                     FILDETKALEREGWDLDEIAVLYRSNAQSRVIEQSLFRSGIPYKIYGGLRFYERQEIK
                     HALAYLRLAVNPDDDNALLRVINFPPRGIGARTVENLQTASQEQGVSLWQAACNAGAK
                     AAKVAAFVRLIEALRNQVGQMPLPEIIAGILKDSGLTEHYRTQKGDNQDRLDNLDELV
                     NAAIEFKPEDSNFETLPDNISDDPAFPILAFLSNAALESGENQAGAGEKAVQLMTVHA
                     AKGLEFNAVFLTGMEEGRFPSEMSLAERGGLEEERRLMYVAITRARKRLYITMAQQRM
                     LHGQTQFGIVSRFVEEIPPEVLHYLSVKKTAYDSYGSPRQTAASKDKIIDDYKQPQTY
                     AGFRIGQNVRHAKFGTGVIIDAADKGESARLTINFGKQGVKELDTKFAKLEEM"
     gene            7273..7812
                     /locus_tag="ACFOV4_000554"
     CDS             7273..7812
                     /locus_tag="ACFOV4_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042546 - cell wall biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="HFC7618628.1"
                     /translation="MSQVFKDFDLSSVWESDSWADENYQEAPFTPEILAAVESELGYK
                     LPQSFIELMAVQNGGIFVKNCFPTTQRNSWAENHVQICEVSGIGFEKEGSLCGETGQK
                     LWLEEWEYPPIGVYFANDPSGGHAMFALDYRACGKDGEPKVVFVEQESDFEIVELAPD
                     FETFIRSLRHEDEFIDEEI"
     gene            complement(8002..8217)
                     /locus_tag="ACFOV4_000555"
     CDS             complement(8002..8217)
                     /locus_tag="ACFOV4_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618629.1"
                     /translation="MNIINYTGDDIIISLTREELQLLRSLVIEIYAGVCIDAEEFEIV
                     SGIRNSKLVQELEQQLIEAYDLMDTKG"
     gene            complement(8341..8700)
                     /locus_tag="ACFOV4_000556"
     CDS             complement(8341..8700)
                     /locus_tag="ACFOV4_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 8 family protein"
                     /protein_id="HFC7618630.1"
                     /translation="MIKLDLKSINLYDIDFEKFTPEIPDNFHRWIDLDIGIEGEQGSS
                     IFSLCICSPKWISHHCNKEGFFWSNALILEQFDHKIIKSEIDKILEYCSKETWDLTLS
                     NLLRFFSWEFEDYNPNT"
     gene            8753..9129
                     /locus_tag="ACFOV4_000557"
                     /pseudo
     CDS             8753..9129
                     /locus_tag="ACFOV4_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060537127.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            9328..9948
                     /locus_tag="ACFOV4_000558"
     CDS             9328..9948
                     /locus_tag="ACFOV4_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused MFS/spermidine synthase"
                     /protein_id="HFC7618631.1"
                     /translation="MNSTASKTLKGLSLVFFASGFCALIYQVSWQRLLFSHIGIDLSS
                     ITVIISVFMVGLGVGAYFGGRIADRFPSSIIPLFCIAEVSIGLFGLVSRGLISGLGHL
                     LVEADLPIIAAANFLLLLLPTFMMGATLPLLTCFFNRKIHNVGESIGILYFFNTLGAA
                     LGSLAAAEFFYVFFTLSQTIALTACFNLLIAASVWLRYRKDGYSEH"
     gene            9971..11422
                     /locus_tag="ACFOV4_000559"
     CDS             9971..11422
                     /locus_tag="ACFOV4_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused MFS/spermidine synthase"
                     /protein_id="HFC7618632.1"
                     /translation="MLSFLSGLLSLGIEVLWVRMFSFAAQSVPQAFSFTLACFLTGIA
                     VGAYFGKRICRSRFVDIPFIGQCFLWAGIADFLILGAAWLLTGFSGFVHHAGIFITLS
                     AVVRGLIFPLVHHVGTDGNKSGRQVSNVYFANVAGSALGPVLIGFVILDFLSTQQIYL
                     LICLISAAVPLFCTLFQKSLRLNAVSVAVSLMFGILMFLLPDSVFQNIADRPDRLIEN
                     KHGIVAVYHRDGDKVVYGANVYDGAYNTDVFNSVNGIERAYLLPSLKSGIRRIFVVGL
                     STGSWARVLSAIPEMQSMIVAEINPAYRSLIADEPQIAPLLQDKRVEIVLDDGRKWLR
                     RHPDEKFDLILMNTTWYWRAYSTNLLSAEFLKQVQSHLTPDGIVMFNTTHSPHAFATA
                     VHSIPYAYRYGHMVVGSATPVVFPNKELLKQRLSRLIWPESGRHVFDSSTVDAAAQKV
                     VSRMLIQMTEPSAGAEVITDDNMIVEYKYGRGI"
     gene            11884..12240
                     /locus_tag="ACFOV4_000560"
     CDS             11884..12240
                     /locus_tag="ACFOV4_000560"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="HFC7618633.1"
                     /translation="MLSAYFPVFVFILVGLAAGVLFILLGTILGPKRHYAEKDAPYEC
                     GFEAFENARMKFDVRYYLVAILFILFDLEVAFMLPWAVVFKDLGVYGFWSMLVFIVVL
                     TVGFVYEWKKGALEWE"
     gene            12231..12713
                     /locus_tag="ACFOV4_000561"
     CDS             12231..12713
                     /locus_tag="ACFOV4_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045271 - respiratory chain complex I
                     [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B family
                     protein"
                     /protein_id="HFC7618634.1"
                     /translation="MGIEGVLKKGFITTSADTVLNYMRTGSLWPVTFGLACCAVEMMH
                     AGMARYDLDRFGIIFRPSPRQADLMIVAGTLTNKMAPALRRVYDQLAEPRWVLSMGSC
                     ANGGGYYHYSYSVVRGADRVVPVDVYVPGCPPTAEALIYGLIQLQQKIKRTSTIARDE
                     "
     gene            12726..13319
                     /locus_tag="ACFOV4_000562"
     CDS             12726..13319
                     /locus_tag="ACFOV4_000562"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HFC7618635.1"
                     /translation="MASIQNLYETVIGVLGNQAGKVISALGEITVECLPEHYISVMTA
                     LRDHEDLHFELLVDLCGVDYSTYKNEVWQGKRFAVVSQLLSVKNNQRIRVRVWVSDDD
                     FPVVESVVDIYNSADWYEREAFDMYGIMFNNHPDLRRILTDYGFVGHPFRKDFPISGY
                     VEMRYDEEQKRVIYQPVTIEPREITPRIVREENYGGQ"
     gene            13309..14565
                     /gene="nuoD"
                     /locus_tag="ACFOV4_000563"
     CDS             13309..14565
                     /gene="nuoD"
                     /locus_tag="ACFOV4_000563"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase (quinone) subunit D"
                     /protein_id="HFC7618636.1"
                     /translation="MANKLRNYTINFGPQHPAAHGVLRMILELEGETIVRADPHIGLL
                     HRGTEKLAETKTYLQALPYMDRLDYVSMMVNEQAYCLAVEKLAGIDVPIRAQYIRVMF
                     AEVTRILNHLMGIGSHAFDIGAMTAILYAFRDREELMDLYEAVSGARMHAAYFRPGGV
                     YRDLPDFMPKYESSKFRNAKVLKQLNESREGTMLDFIDAFCERFPKNIDTLETLLTDN
                     RIWKQRTVGIGVVSPERAMQKGFTGVMLRGSGVEWDVRKTQPYEVYDKMDFDIPVGVN
                     GDCYDRYLCRMEEMRQSVRIIKQCSEWLRVNPGPVITTNHKFAPPKRTEMKTGMEDLI
                     HHFKLFTEGMHVPEGETYTAVEHPKGEFGVYIISDGANKPYRLKIRAPGFAHLQGMDE
                     MAKGHMLADVVAIIGTQDIVFGEVDR"
     gene            14565..15038
                     /gene="nuoE"
                     /locus_tag="ACFOV4_000564"
     CDS             14565..15038
                     /gene="nuoE"
                     /locus_tag="ACFOV4_000564"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HFC7618637.1"
                     /translation="MLSAESLKQIDTELAKYPADQRRSAIMGALRIAQTEKGWLAPET
                     IAFVADYIGITPAQAYEVATFYNMYDLEPVGKYKLTVCTNLPCALRGGMATGEYLKQK
                     LGIGYGETTPDGKFTLVEGECMGACGDAPVMLVNNHSMCSFMTEEAIEKKLAELE"
     gene            15428..16729
                     /gene="nuoF"
                     /locus_tag="ACFOV4_000565"
     CDS             15428..16729
                     /gene="nuoF"
                     /locus_tag="ACFOV4_000565"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HFC7618638.1"
                     /translation="MAIYQSGVIFDQVDTANPDCWTLDEYVKRGGYTALRKILSENIS
                     QTDVIDEVKTSGLRGRGGAGFPTGLKWSFMPRSFPGEKYVVCNTDEGEPGTFKDRDII
                     MFNPHALIEGMIIAGYAMGAKAGYNYIHGEIFEGYQRFEAALEQARAAGFLGKNILGS
                     DFEFELFAHHGYGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTET
                     FSSVSFIIRDGGQAFADKGIPNAGGTKLFCISGHVERPGNYEVPLGTPFAEVLKMAGG
                     MRGGKKLKAVIPGGSSAPVLPADIMMQTNMDYDSISKAGSMLGSGAIIVMDEDVCMVK
                     ALERLSYFYYDESCGQCTPCREGTGWLYRIVHRIVEGKGRMEDLDLLDSVGNQMAGRT
                     ICALADAAVFPVRSFTKHFRDEFVHYIEHGGPMKEHKWGGW"
     gene            16729..17166
                     /locus_tag="ACFOV4_000566"
     CDS             16729..17166
                     /locus_tag="ACFOV4_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618639.1"
                     /translation="MVEAKIFILYGAANKGKSTTLNTLFNQICWKFSKFLVFFERHGN
                     GLDFVAVFDHEGQRIGFYSSGDNEYEVRRNLYKLYSHNCDFIFGTSRTRGGSCDAVGC
                     YAELLHGDVNIINWCEKFEPTDEDNERAVKELFKSFKNIINEL"
     gene            17456..19717
                     /gene="nuoG"
                     /locus_tag="ACFOV4_000567"
     CDS             17456..19717
                     /gene="nuoG"
                     /locus_tag="ACFOV4_000567"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003776117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006120 - mitochondrial electron transport,
                     NADH to ubiquinone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HFC7618640.1"
                     /translation="MLQIEIDGKQVSVEQGATVIEAAHKLGTYIPHFCYHKKLSIAAN
                     CRMCLVNVEKAPKPLPACATPVTDGMIVRTHSAKAREAQEGVMEFLLINHPLDCPTCD
                     QGGECQLQDLAVGYGKTTSRYTEEKRSVVGKDMGSLVSAEEMSRCIHCTRCVRFTEEI
                     AGLQEIAMVNRGEHSEIMPFIGKTVETELSGNVIDLCPVGALTSKPFRFNARTWELNR
                     RKSVSAHDALGSNLIVQTKDHTVRRVLPLENEAINECWLSDRDRFSYEGLYHESRLKK
                     PKIKQGGEWMDVDWKTALEYVRSAIECIAKDGNQNQVGIWANPMNTVEELYLAKKLAD
                     GLGVKNFATRLRQQDKRLSDGLKGAQWLGQSIESLADNDAVLVVGANLRKEQPLLTAR
                     LRRAAKDRMALSVLAGSKEELLMPLLSQEAAHPDEWAGRLKNLSANAEHAVTASLKNA
                     EKAAVILGAEVQNHPDYAAIYAAAQELADATGAVLGILPQAANSVGADVLGVNSGESV
                     TEMANAPKQAVLLLNVEPEIDTVDGAKAVAALKQAKSVMAFTPFVSETLLDVCDVLLP
                     IAPFTETSGSFINMEGRLQSFHGVVQGFGDSRPMWKVLRVLGNLFDLKGFEYHDTAAI
                     LKDALDAESLSSKLDNRSTWTGEGVQTASDRLVRVGGVGIYHTDAIVRRSAPLQETSH
                     AAVPAARVNPNTLARLGLQDGQTAVAKQNGASVSVAVKADAGLPENVVHLPLHTENAA
                     LGALMDTIELAGA"
     gene            19720..20796
                     /gene="nuoH"
                     /locus_tag="ACFOV4_000568"
     CDS             19720..20796
                     /gene="nuoH"
                     /locus_tag="ACFOV4_000568"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HFC7618641.1"
                     /translation="MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVA
                     YLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFKLLFKEVTRPKLSNKALFYIGPI
                     MSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGA
                     MRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIF
                     IVYLISAVAETNRAPFDVAEGESEIVAGHHVEYSGFAFALFFLAEYIFMILIAALTSL
                     MFLGGWLSPFPQSWGFIGTPSAFWMFVKMAAVLYWYLWIRATFPRYRYDQIMRLGWKV
                     LIPIGFAYIVVLGVWMISPLNLWK"
     gene            20877..21356
                     /gene="nuoI"
                     /locus_tag="ACFOV4_000569"
     CDS             20877..21356
                     /gene="nuoI"
                     /locus_tag="ACFOV4_000569"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HFC7618642.1"
                     /translation="MANLVKTFLLGELVKGMGVTLKNFFARKDTIYFPEEKTPQSVRF
                     RGLHAQRRYPNGEERCIACKLCEAVCPAMAINIESEEREDGTRRTKRYDIDLTKCIFC
                     GFCEEACPTDAIVETHIFEYHGEKKGDLHMTKPILLAIGDKYEAEIAKRKAADAPYR"
     gene            21368..22039
                     /locus_tag="ACFOV4_000570"
     CDS             21368..22039
                     /locus_tag="ACFOV4_000570"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HFC7618643.1"
                     /translation="MTFSAILFYILATIVLYGALRTVTAKNPVHAALHLVLTFCVSAM
                     LWMLMQAEFLGVTLVVVYVGAVMVLFLFVVMMLNIDIEEMRAGFWRHAPVAGVVGTLL
                     AVALILILVNPKTDLAAFGLMKDIPADYNNIRDLGSRIYTDYLLPFELAAVLLLLGMV
                     AAIALVHRKTINPKRMDPADQVKVRADQGRMRLVKMEAVKPQVESAEESEVSDGLKPE
                     GEGKA"
     gene            22036..22341
                     /gene="nuoK"
                     /locus_tag="ACFOV4_000571"
     CDS             22036..22341
                     /gene="nuoK"
                     /locus_tag="ACFOV4_000571"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HFC7618644.1"
                     /translation="MITLTHYLVLGALLFGISAMGIFMNRKNVLVLLMSIELMLLAVN
                     FNFIAFSQHLGDTAGQIFVFFVLTVAAAESAIGLAIMVLVYRNRQTINVADLNKLKG"
     gene            22636..23508
                     /locus_tag="ACFOV4_000572"
     CDS             22636..23508
                     /locus_tag="ACFOV4_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFC7618645.1"
                     /translation="MSFSIALPLVYLFIGILIGKTPFRKIKGTFSVILSRWIIPFVIV
                     YNITTYRDGMQYVMLWMIISMGLIILIGKRVDKDPVWNLCLCYLNIGWLGLPIVATLF
                     GDEAAQVLISAYVGSSLFGNSVGVGLLLNNSNFISGLKKTLKSPPVVALVIGMFGIPL
                     GHFVADYFGEVYFFSKIAMGILGMVILGIWLAEIKLNLNDLKKSIKPFLIKNILFIGI
                     VFLFIQIAAYFDLKLILENQKTLYLIPLLPPAANIIVLETAYLKTGRSASMIAYGTIF
                     SLIAISIYILLVQI"
     gene            23509..25533
                     /gene="nuoL"
                     /locus_tag="ACFOV4_000573"
     CDS             23509..25533
                     /gene="nuoL"
                     /locus_tag="ACFOV4_000573"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HFC7618646.1"
                     /translation="MNDMTLYLIIALVPLAGSLIAGLFGNKIGRAGAHTVTILGVAVS
                     AVLSAYVLWGFLNGSRAKFDENVYTWLTMGGLDFSVGFLVDTMTAMMMVVVTGVSLMV
                     HIYTIGYMHDEKVGYQRFFSYISLFTFSMLMLIMSNNFIQLFFGWEAVGLVSYLLIGF
                     YFKRPSATFANLKAFLINRVGDFGFLLGIGLVLAYFGGSLRYQDVFAYLPNVQNATIQ
                     LFPGVEWSLITVTCLLLFVGAMGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGL
                     FMVSRMSPIYEMSSTALSVIMVIGAITALFMGFLGVIQNDIKRVVAYSTLSQLGYMTV
                     ALGASAYSVAMFHVMTHAFFKALLFLAAGSAIIGMHHDQDMRHMGNLKKYMPITWLTM
                     LIGNLSLIGTPFFSGFYSKDSIIEAAKYSTLPGSGFAYFAVLASVFVTAFYAFRQYFM
                     VFHGEEKWRSLPEHHDDHHGEEHHSLGKNDNPHESPLVVTLPLILLAIPSVIIGYLAI
                     EPMLYGDFFKDVIFVNTDAHPTMHIMKEEFHGALAMVSHSLHSPVLYLAIAGVLSAWL
                     LYVKLPHLPAKIAQTFRPIYVLFENKYYLDALYFNVFAKGTRALGTFFWKVGDTAIID
                     NGIVNGSAKLVGAIAAQVRKAQTGFIYTYAAAMVFGVLVLLGMTFWGLFR"
     gene            25717..26880
                     /locus_tag="ACFOV4_000574"
     CDS             25717..26880
                     /locus_tag="ACFOV4_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HFC7618647.1"
                     /translation="MTQLFLHSDTPNEKELISIYEKAVSEAVELYIFSAYLTHWDVKN
                     KLNSKLQEFKFIFGQDFGLSKKEAIRKVLKWLPSHLKFTLMVAQGIQGFHPKAVFWKN
                     DKNEYYALIGSSNLTHAAFNSNYEANILTKISEQDFIKVKSWADEIAMKSIPVSEDWL
                     EEYQEAEINYKKSTVSQSLMDKLFMEMPNYNQELIAARRKQMRNHQTVCNQLKSLIKQ
                     CAAGKIDNDEFYVEFNKLWSWKSENKGEGVGNRFQDQTWKRTGKSSDFRKLCIAIQSV
                     FDAPLAERDNVVAKQIDWLKECGVSTRGSVFSEMLCQEYPDRYPVLNAPIKKFLEKNK
                     FKSAKGASEGSRYIDLSMKLRALLAMQSEIKNLAELDVLVQAEYRDSTDIDWE"
     gene            26990..28486
                     /locus_tag="ACFOV4_000575"
     CDS             26990..28486
                     /locus_tag="ACFOV4_000575"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HFC7618648.1"
                     /translation="MFSNYLLSLAIWIPIAAGVLVLSTGKDSRAPLARVLAFMGALAG
                     FLVTLPLFTGFDRLSGGYQFTEFHEWIPLLKINYALGVDGISVLFIILNAFITLLVVL
                     AGWEVIQKRPAQYMAAFLMMSGLINGAFAAQDAILFYVFFEGMLIPLYLIIGVWGGPR
                     RVYASVKLFLYTLMGSLLMLVAMVYLYYQTGSFSIVDFQNIKQIPLGVQQLLFVAFFL
                     SFAVKVPMFPVHTWLPDAHVEAPTGGSMVLAAITLKLGAYGFLRFILPIMPDAARYFA
                     PVIIVLSLIAVIYIGMVALVQTDMKKLVAYSSISHMGFVTLGMFLFVDGQLDDWALKG
                     AVIQMISHGFVSAAMFMCIGVMYDRLHTRNIADYGGVVNVMPKFAAFMMLFGMANAGL
                     PATSGFVGEFMVIMGAVKVNFWVGALAAMTLIYGASYTLWMYKRVIFGEIRNPHVADM
                     KDINCREFAVLAVLAAAVLGMGLYPNAFIEVVHQAANDLIAHVAQSKI"
     gene            28496..29941
                     /gene="nuoN"
                     /locus_tag="ACFOV4_000576"
     CDS             28496..29941
                     /gene="nuoN"
                     /locus_tag="ACFOV4_000576"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HFC7618649.1"
                     /translation="MNWSDLNLMPAMPEIVLLSLLVLLLLADLWVSDDKRRWTHYGAL
                     ATVAVTAVVQLAVWEQGSTSSFNGMYIADGMSRLAKMVLYALTFALFVYARPYNQVRG
                     IFKGEFYTLSLFALLGMGVMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAAL
                     KYFVLGALASGLLLYGISMVYGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVG
                     FKLGAVPFHMWVPDVYHGAPTSVTALVGTAPKVAAVVFAFRILVTGLGTVHHDWSLMF
                     ALLAAASLLVGNLAAIMQTNIKRMLAYSTVSHMGFILLAFMAGAVGFAAGLYYAITYA
                     LMAAAGFGVLMVLSDGDNECENISDLAGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYA
                     KFGVIMALLKQGYVWLSVFAVVMSLIGAFYYLRVVKVMYFDESGRARLAAGGNNAAKF
                     LLSVNALLLVLWGIMPQTVIDWCAKALENTL"
     gene            30053..30352
                     /locus_tag="ACFOV4_000577"
     CDS             30053..30352
                     /locus_tag="ACFOV4_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2818 family protein"
                     /protein_id="HFC7618650.1"
                     /translation="MTASMYILLVLALIFANAPFLTTRLFGVAALKRKHFGHHLIELA
                     AGFALTAVLAYILESRAGAVHNQGWEFYATVVCLYLIFAFPCFVWRYFWHTRNRE"
     gene            complement(30461..31357)
                     /locus_tag="ACFOV4_000578"
     CDS             complement(30461..31357)
                     /locus_tag="ACFOV4_000578"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFC7618651.1"
                     /translation="MNPTNDLKAWQLRAQAQTELLLERFLPSEGEIPHTLHEAMRYAA
                     LDGGKRLRPMLVLAASELGGAVADAVGQAMAAIEMIHVYSLVHDDMPAMDNDSLRRGK
                     PTCHIQYDEATALLVGDALQTQAFDVLSRPTELPAARQLAMLSVLAKAGGSAGMAGGQ
                     AIDLANVGKQMVQADLEQMHSLKTGALIRAAVLLGAMSCPNLSEDSLAVLDDYAAKLG
                     LAFQVIDDVLDCEADTATLGKTAGKDADNDKPTYVKLMGLEAARSYAHKLVAEAVALL
                     EPFGDKALRLRQLAEFAVARKY"
     gene            complement(31341..31565)
                     /locus_tag="ACFOV4_000579"
     CDS             complement(31341..31565)
                     /locus_tag="ACFOV4_000579"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009115303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFC7618652.1"
                     /translation="MKKNAPKSFEEALSRLESLTQSMQGEMPLEDALAAYQEGNELVR
                     YCQTKLAQVEQKLQVLDADGLKELNLESDE"
     gene            complement(31812..32735)
                     /gene="rsgA"
                     /locus_tag="ACFOV4_000580"
     CDS             complement(31812..32735)
                     /gene="rsgA"
                     /locus_tag="ACFOV4_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFC7618653.1"
                     /translation="MPSEHPFSDGISTPNPKETMNDTAQITASYGRRYIVRTPDGTTY
                     EASTRKKRVDFACGDRVRISPVNAEQVVIEDFLPRQSLLYRQDAWKTKLIAANVTQLL
                     IVTAAVPSPSVRLLQRALLAAEAAGIEAVIVLNKADLPETALWREKLKFYETLGYPVI
                     ETRALENAGSLRPALQGHSNILLGQSGMGKSTLTNALLGSQTARTGDISAALDSGKHT
                     TTHARLYDLNGETQLIDSPGLQEFGLHHLQAADLPRYFPDFRHLVGQCRFHNCTHRAE
                     PGCAFKAAAQTGAASPERLAFLQGITDELPG"
     gene            complement(32740..34596)
                     /locus_tag="ACFOV4_000581"
     CDS             complement(32740..34596)
                     /locus_tag="ACFOV4_000581"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC7618654.1"
                     /translation="MLNKIFSWFESRIDPYPEAAPKTPEKGLWRFVWSSMAGVRKWIA
                     ALAALTAGIGIMEALVFQFMGKIVEWLGKYAPAELFAEKGWELAAMAAMMVFSVVWAY
                     AASNVRLQTLQGVFPMRLRWNFHRLMLNQSLGFYQDEFAGRVSAKVMQTALALRDAVM
                     TVADMVVYVSVYFITSGVILASLDSWLLLPFIGWIVGFASVMRLLIPKLGQTAAWQAD
                     ARSLMTGRITDAYSNIATVKLFSHGAREAAYAKQSMEEFMVTVRAQMRLATLLHSCSF
                     IVNTSLTLSTAALGIWLWHNGQVGVGAVATATAMALRVNGLSQYIMWESARLFENIGT
                     VGDGMATLSKPHTILDKPNALPLKVSQGEIKFEHIDFCYEAGKPLLNGFNLTIRPGEK
                     VGLIGRSGAGKSTIVNLLLRFYEPQSGTVSIDGQDISGVTQESLRAQIGLVTQDTSLL
                     HRSVRDNIIYGRPDATDAEMVSAAERAEAAGFIPELSDAKGRRGYDAHVGERGVKLSG
                     GQRQRIAIARVMLKDAPILLLDEATSALDSEVEAAIQESLDKMMDGKTVIAIAHRLST
                     IAAMDRLVVLDKGRIIEEGIHAELLEKRGLYAKLWAHQSGGFLNEHVEWQHD"
     gene            complement(34622..34759)
                     /locus_tag="ACFOV4_000582"
     CDS             complement(34622..34759)
                     /locus_tag="ACFOV4_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618655.1"
                     /translation="MPSEGGAAFALTKPCVSASRCLPDGFSRKMALLSFLSDGIVFDA
                     V"
     gene            complement(34759..35343)
                     /gene="ruvA"
                     /locus_tag="ACFOV4_000583"
     CDS             complement(34759..35343)
                     /gene="ruvA"
                     /locus_tag="ACFOV4_000583"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFC7618656.1"
                     /translation="MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGES
                     VQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGGIGAKTALGILSAMTADELARAV
                     AEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAAAPAADETEDIVSTLLA
                     LGYSEREAKAAVKGVPKGTDVGEGVRLALKNLLK"
     gene            complement(35425..35751)
                     /locus_tag="ACFOV4_000584"
     CDS             complement(35425..35751)
                     /locus_tag="ACFOV4_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFC7618657.1"
                     /translation="MNIKHLLLTAAATALMGISAPALAHHDGHGDDDHGHAAHQHSKQ
                     DKIISRAQAEKAALARVGGKITDIDLEHDNGRPHYDVEIVKNGQEYKVVVDARTGRVI
                     SSRRDD"
     gene            complement(35813..36532)
                     /locus_tag="ACFOV4_000585"
     CDS             complement(35813..36532)
                     /locus_tag="ACFOV4_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring lytic transglycosylase RlpA family
                     protein"
                     /protein_id="HFC7618658.1"
                     /translation="MTLTRKTLFLLTAAFGTHSLQTASADAVVKAEKLHASANRSYKV
                     AGKRYTPKNQVAEFTQTGNASWYGGRFHGRKTSGGERYDMNAFTAAHKTLPIPSYVRV
                     TNTKNGKSVIVRVNDRGPFHGNRIIDVSKAAAQKLGFVSQGTAHVKIEQIVPGQSALV
                     AENKDIFIDLKSFGTEHEAQAYLNQAAQNLASSASNPNLSVEKRHYEYVVKMGPFSSQ
                     ERAAEAEAQARGMVRAVLTAG"
     gene            complement(36529..36651)
                     /locus_tag="ACFOV4_000586"
     CDS             complement(36529..36651)
                     /locus_tag="ACFOV4_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFC7618659.1"
                     /translation="MPSENLSGHIPNRRPHCTAVRNVSGGHDAHSSSTQERNTF"
     gene            complement(36662..37126)
                     /gene="trmL"
                     /locus_tag="ACFOV4_000587"
     CDS             complement(36662..37126)
                     /gene="trmL"
                     /locus_tag="ACFOV4_000587"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFC7618660.1"
                     /translation="MFTIVLYQPEIPPNTGNIIRLCANTGADLHLVKPLGFPLDSAKM
                     KRAGLDYHEFASLTVHENFDDCLKALAGRRIFALTTKGTARPDETAFQKGDVLLFGPE
                     TRGLPADILDSLPAAQKIRLPMQPGSRSMNLSNTVAVILFEAWRQHGYAGGV"
     gene            complement(37191..37916)
                     /locus_tag="ACFOV4_000588"
     CDS             complement(37191..37916)
                     /locus_tag="ACFOV4_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFC7618661.1"
                     /translation="MDFLSCWRRIADAPTIRRCVLCHGSSGVSDGICAGCRDDLAAYR
                     TDAANSCPLCFMHVQGGAVCGGCQKKPPAFDRMWASLHYEPPVSNMIHALKHLADLSM
                     VQPLADLMMQNPPDRLADECFDFVLPVPLSRERLLQRGFNQSESIVGLLAQRYGWQIL
                     PRHTVFRHHRPPQSTLKGGERRRNIKNAFEIRTPIPENCNILLIDDVFTTGATLDELA
                     KTLKKSGANRICCWTLARTPMKK"
     gene            37915..38658
                     /gene="bioH"
                     /locus_tag="ACFOV4_000589"
     CDS             37915..38658
                     /gene="bioH"
                     /locus_tag="ACFOV4_000589"
                     /EC_number="3.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HFC7618662.1"
                     /translation="MPDAVKKVYLIHGWGANRHVFDDLMPRLPATWPVSAVDLPGHGD
                     APFAQPFDIEAAADAVAAQIDTPADILGWSLGGLVALYLAARHPDKVRSLCLTASFAR
                     LTADEDYPEGLAAPALGKMVGAFRTDYAKHIKQFLQLQLLHTPDADGIIGRILPDLAR
                     CGTPSALQEALDAAERADARHLLDKIDVPVLLVFGSKDAITPPRMGEYLHRRLKGSRL
                     VVMEKAAHAPFLSHAEAFAALYRDFVEGV"
     gene            38660..39448
                     /locus_tag="ACFOV4_000590"
     CDS             38660..39448
                     /locus_tag="ACFOV4_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HFC7618663.1"
                     /translation="MNPQDKCWQVHRHLAEYADQRLTLVRNAPKYILLAGADADISRS
                     LLAKRYPQAVFEEYDSRADFLAAAAAARKGGFWQRFTGKGVVQHCQSPIAPLPEACAD
                     MLWSNLGLLAAEQILPVLHNWARALKTDGLLFFTCFGRDTFTELKCRLKENGIESRSV
                     MFPDMHDLGDMLAENGFYDPVTDTAKLVLDYKKAETFWADMDTLGVWRAMAWNDENAA
                     RSCVGTIFEREGGLSITLETVYGHAVKKLMLPQGENVVQFFPKR"
     gene            39586..39855
                     /locus_tag="ACFOV4_000591"
     CDS             39586..39855
                     /locus_tag="ACFOV4_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618664.1"
                     /translation="MYCLRLRRLVLIFVNPLYADAGDVYCVYNIRLKQYTACQVTRVE
                     EHGGKKTHATLLALDWQGNKPLGAEELADLKPLYKDLKNNIGNIV"
BASE COUNT         9161 a        10096 c        10667 g        10087 t
ORIGIN      
        1 cctctttcag ttacagcagc ttgatccctt tcccttatcc aacgggggaa ggctaggata
       61 gggtggcttg caaatataca gaacaaggga caagagccac cctctctcca accctctccc
      121 tccgtacggg agggggtgga ttctcgcggg cgaagcccac gctacggtta gcctttaccc
      181 cagcacaaac aattcccgcc cgtgcgcctt cagccaactt ttagcattgt cggtatgcgg
      241 cgtcagcgtg ttcaccaaat gccaaaagcg cggactgtgg tcggggtggc ggaggtggca
      301 gagttcgtgg atgcagacat agtcggcaac gtacttgggc gcgccgatca gccgccagtt
      361 gaggcggatg ccggtgtgcg ggcggcatac gccccaaaag gttttggcgt tgctcaggtc
      421 tgtggcggtg ggcgtcagtc ctgtttcggc tgcgtgtttt tcaaggcggg gcagcaggta
      481 ttcgcgggcg cgttcgttca acaggcggcg caggtggtcg atttgtgcgg cggtttcttt
      541 tcggggaagc aggatttcag acgacgtgat acggatatgg ctttggctgt gggtatccag
      601 cttggtcttt attccccgat accaaatcca ctcgggtaag tttgggtggg aaacaggatg
      661 cacgggcgtt ttggcaagcg tgttccgcaa aatcgtttcg tttgccgcca gccagtttgc
      721 taacgcgtgg tcttgaaaaa agggtgggac gttgatgctg accgtctgca tattgacggg
      781 gcgcagaatc agatttttct tggcactgcg tttgagttcg atttcgatgc acaagccgtc
      841 ggaaagagta taggtgaagc gtttcatagt tgtgaatagg tttcagaccg gatacatcgt
      901 ctgaaacagg aattttccat atcaggcggc aaacttcgga taatatacaa aatcaaacat
      961 ctgcgctaca aggttcagcc gaacaagccg ccgatatatt tgctgatggt gatggcgctg
     1021 agtactgcca tcaaaccgac cacaatcacg ccggaaacgg tgagccacag cgggtgtttg
     1081 tagtcgccga caattttggt tttgtaggcg gcaatcagaa tcagaccgag ggaaatcggt
     1141 aaaatcaggc cgtttaatgc gcctacgaac accagcacct gcgccggttt gccgatggtg
     1201 gaaaatacgg cggtggacac ggcgataaag gcaataatcc atttgttttt attgcgttcg
     1261 atagacgggc tgagaccgga gaagaacgac accgaagtat aagccgcacc aatcaccgaa
     1321 gtaatcgaag ccgcccaaat caccacgccg aaaatcagca ggccgatgta tcccgccgca
     1381 tattcaaacg gtgtggaagc agggttgtcg ggattgagct gtacgccttg gctgaccacg
     1441 cccaaaaccg ccaaaaacaa tacaatccgc ataatcgagg caatcaggat cgcccgcacc
     1501 gagctttggc tcacttccgg caacgccgat ttgcctttga tgcctgcgtc cagcagacgg
     1561 tgcgcaccgg cgaaggtgat gtagccgccg accgtgccgc ccaccagtgt aacaatcgcc
     1621 attgcatcga gtttttccgg cataaaggta tgcacggcgg catctgccag cggcggattc
     1681 gcctgccatg ccacataaac cgtcagcgca atcattacga aacccatcac ttgggcgaat
     1741 ttgtccatca ctttgcctgc ttctttaaac agaaacacac cgatggcaat cacgccgctg
     1801 atcacggcac cggtttccgg cgacagtccg gtcagcaggt tcagacccaa gcctgcgccg
     1861 ccgacgttgc caatattgaa cgccaaaccg cccatcacaa tcagcacagc caagaaatag
     1921 cctgcgccgg gcaagacctg attggcaata tcctgcgcct gtttttcgga aacggcgaca
     1981 atccgccaaa tattgagctg cgccccgatg tcgagcagaa tcgagagcag aatcacaaag
     2041 ccgaaacttg ccgccagtgc ttgggtgaag gtggcggttt gggtcagaaa gcccgggccg
     2101 atggcggaag tcgccatcag gaatgcagcg ccgattaagg catttctgcg gtttttttga
     2161 tcagacataa tcgcttatcc tctataaaat tggttgttgc tgtgtttggg cgaaacctgc
     2221 ggttttagct acgcagaaac tcgctttgct cgttttggcg aaacctgcgg ttttcagacg
     2281 gcctatgaac tgtttttcaa gcagaaactt tgatgcctgc cgccagtagt tcctgccgga
     2341 ttttttcggc aaacaccacg gcgtgcggcc cgtctccgtg cagacagatg ctgtcggctt
     2401 gcacggcaac caggctgccg ttcactgctt tgacccgccc gtcccgcacc atctgcaata
     2461 cttgggcgat ggcttcttcg tcgctgtcaa cctgcgcatc ggggcggctg cggggaacca
     2521 gcgtaccgtc gggcatatag cggcggtcgg cgaatacttc ggaaatcaca cccaagcctg
     2581 cggcttttcc ggcttccaag agcaggctgc cggaaagtgc catcaatttc aatttcgggt
     2641 cgaaatccgc cacaattcgg gcaacggtat ccgccagcgc acggtttttc gccgcttggt
     2701 tgtacattgc gccgtgcggt ttgacataag ccatttccaa accctgatca cggcacaagg
     2761 cctgcaatgc gcccaactgg taattcagac acgcccgcaa atcggcttcg gacagattca
     2821 tttcggtacg gccgaagttt tcccgatcgg gatagccggg gtgtgctccg atgcgcacgc
     2881 cgttttgttg ggcatacgcc aatgccgccc gaatatcggc aatgctgccg gcgtgttggg
     2941 cgcaggcgat gttggccgaa gtaatcagct gcaacaaggc ttcgtcgctg ccgcagcctt
     3001 cggcgagatc ggcgtttaaa tcaacctgct tcatgggtga ttctccgtat ttggttcaga
     3061 taggcttggt ttttgcgccg cagggcggtg gcttctttca agccgattat tttgaatttg
     3121 actttgctgc cgaagcgcac ctgtgccagc ctgcccaaat cggcggcggc aacggtagcg
     3181 attttcggat aaccgccggt ggtttgtgca tcggccagca ggataatcgg tttgccgccg
     3241 ggcggcacct gcacggttcc tgcctgaaca gcgtgggaca gcatttccaa aggttgcgac
     3301 agggtcagcg gctgtccgtc gaagcggtag cccatgcggt tgctatcgct ttgcagcgtc
     3361 cacgtttccc gttccagatt cagacgccct ttttcactga aagcggcata ttccgacgaa
     3421 ggaacaaggt ggacggtatc ggtaaacggt atcggggcaa tgccgacttt ggacaattcc
     3481 tgcgcacctt tgccgatggg gagataatcg cctttttgca gcattctgcc ctgatggccg
     3541 ccgaaaccgg ctttcaggtc ggtacttctc gaacccatca cttccggcac atcaaatccg
     3601 cccgccacgc acacatagcc gtacatgccc tgcacggcac gcaccatttt caaggtctgc
     3661 cctttgcggg cggtataacg ccaatacgaa tagaccggtt cgccgtccaa ttccgcctga
     3721 tacacggcac cggtgagaca aaacggcgta tcccgttcaa acaccagcat tatcccgccc
     3781 aaagcgattt cgattgcggc cgtgccttcg tcgttgccca ataaaatatt acccgccgcc
     3841 aaagcaaccg tgtccatcgc accggcatga ccgatgccgt aacgccggtg tccgtagcgt
     3901 ccggtatcct gaatatgcgc cggtgcctgc actgccgaaa cgtgaatcat ggctcaatcc
     3961 tttctgcaac aaagcggact tggtcacccg ccgccagcag ggtcggcgga ttcaaatcgg
     4021 ctcggaacaa gggtaattcg gttctgccga taatctgcca gccgccgggc gaagcgaacg
     4081 gatacacacc ggtctgactg ccgccgatac cgaccgaacc ggcaggaacg gacgttctcg
     4141 gcacggcacg gcggggcgtg tgcaatgctt cgggcaagcc gcccagataa gggaaaccgg
     4201 gctggaagcc catcataaat acggtataag tttgcgccgt atggcggcgg acgatttcgg
     4261 aaataaccgt ctgatggaaa gcagcgactt ccgccaaatc cgggccgtat tcgccgccgt
     4321 agcagacggg aatttccacc agtttgccct gatggtctgt aacggcggtg tgttcccaca
     4381 catattgcaa ttcatcggca agcgtcgcca aatcggtatc gaaacgggta aacacggtca
     4441 gattgttcat gccgaccacc acttcctcaa tcctgtcgtg ctgcccgagc gcagcggcaa
     4501 acgcccacaa cttttgctgt ttgcccagtt cggaaggcgc attcagtcgg cagaccaaag
     4561 cggattcgct gattggtgtg atctctattc tcatttgttg ttcattttgg ttatgtttta
     4621 atgaatctat atgcaggggc ggcggtttgt caatatcttc tgtgctgcat catcaaaccg
     4681 tcgattggaa aagtgctgcc ctgccgctgc actttttcag acgaccttaa accgtttcta
     4741 ttaaaatagc gcattccact tttcagacgg catccttatg tttcccgacc aatccgcccc
     4801 caacctgctg caaggcttga atcccgaaca actctccgcc gtaacctggc cgccgcaatc
     4861 cgcacttgtg ctggcgggcg cgggcagcgg caaaacgcgc gtgctgacca cgcgcatcgc
     4921 atggctgttg caaaccggtc aggcaagcgt gcacagcatt atggcggtaa cgtttaccaa
     4981 caaagccgcc aaagaaatgc aaacccgttt gggcgcgatg attcccatca atgtccgcgc
     5041 catgtggctc ggcacgttcc acggcctctg ccaccgcttt ttgcgcctgc accaccgcga
     5101 cgccggtctg ccgtcttcct ttcaaatcct cgacggcggc gaccagcttt ccctcatcaa
     5161 acgcctgctc aaaagcctca acatcgccga agaaatcatc gcgccgcgtt cgctgcaagg
     5221 ctttatcaac gcgcaaaaag aatccggttt gcgcgcttcc gtcttgagtg cgcccgatcc
     5281 gcacacaagc cgcatgattg aatgctacgc cgaatacgac aaaatctgcc aacgcgaagg
     5341 cgtggtcgat tttgccgaac tcatgctccg cagctacgaa atgctgcaaa gcaacgaaat
     5401 cctgcgccag cattaccaaa accgcttcaa ccacattctc gtcgacgagt tccaagacac
     5461 caacaaactg caatacgcct ggctcaaact catggcgggc ggaaacgcag cggtatttgc
     5521 cgtcggcgac gacgaccaaa gcatttaccg tttccgtggc gcaaacgtcg gcaacatgac
     5581 cgcgctgatg gaagaattcc acatcgacgc gcccgtcaaa ctcgaacaaa actaccgctc
     5641 cgtcggcaac atccttgccg ccgccaatgc cgtgattgaa aacaacgacg aacgactcgg
     5701 caaaaacctg cgcaccgacg ccgaagcagg cgacaaaatc cgctactact ccgcctttac
     5761 cgacctcgaa gaagcccggt tcatcttgga cgaaaccaaa gccctcgaac gcgaaggctg
     5821 ggatttggac gaaatcgccg tcctctaccg tagcaacgcc caatcccgcg ttatcgaaca
     5881 aagcctgttc cgcagcggca tcccctacaa aatctacggc ggcttgcgct tttacgaacg
     5941 ccaagaaatc aaacacgcgc ttgcctatct gcgcctcgcc gtcaatcccg acgacgacaa
     6001 cgccctcttg cgcgtgatta acttcccacc gcgcggcatc ggcgcacgca ccgtcgaaaa
     6061 ccttcagacg gcatcgcaag agcaaggcgt ttcactttgg caggcagcct gcaatgccgg
     6121 cgcaaaagcc gccaaagtcg ccgccttcgt ccgcctcatt gaagccctgc gcaaccaagt
     6181 cggacaaatg cccctgcccg aaatcatcgc cggcatcctc aaagacagtg gcttgaccga
     6241 acactaccgc acccaaaaag gcgacaacca agaccgcctc gacaaccttg acgaactcgt
     6301 caacgccgcc atcgagttca aacccgaaga cagcaacttt gaaaccctgc ccgacaacat
     6361 ttcagacgac cccgccttcc ccatcctcgc tttcttgagc aacgccgccc tcgaatccgg
     6421 cgaaaaccaa gcaggcgcag gcgaaaaagc cgtccaactg atgaccgtcc acgccgccaa
     6481 aggcttggaa ttcaacgccg tcttcctcac cggcatggaa gaaggccgct tccccagcga
     6541 aatgagcctt gccgaacgcg gcggcctcga agaagaacgc cgcctcatgt acgtcgccat
     6601 cacccgcgcc cgcaaacgcc tctacatcac catggcgcaa caacgcatgc tgcacggaca
     6661 aacccaattc ggcatcgtct cccgcttcgt cgaagagatc ccacccgaag tattgcacta
     6721 cctgtccgtc aaaaagaccg cctacgacag ctacggcagc ccgcgccaaa ccgccgcatc
     6781 caaagacaaa atcatcgacg actacaaaca gccccaaacc tacgcaggtt tccgtatcgg
     6841 acaaaacgtc cgccacgcca aatttggcac cggcgtgatt atcgatgccg cagataaagg
     6901 cgaatccgcc cgactgacca tcaatttcgg caaacagggc gtgaaagagt tggacaccaa
     6961 gtttgcgaaa ttggaagaga tgtaaatttg aaatgcaggc tggatactcg tatccgacct
     7021 atggcaaaaa actgtagcaa ggacaaggca aaaggccgtc tgaatccggt aacaacaaat
     7081 tttgccgaaa cctccgccgt cattcccgcg caggcgggaa tccagacctt tcggcacgga
     7141 aacttatcgg ataaaaggtt tctttagatt ccacgttcta gattcccgcc tgcgcgggaa
     7201 tgacggacgg taaaagccgg gtatagatac ctaacccttg tttatagctg aaaatcaata
     7261 aggaagaaca ttatgtccca agtttttaaa gattttgatt tgtcctccgt atgggaatcc
     7321 gacagttggg cagatgaaaa ctaccaagaa gccccgttta cccctgaaat tttggctgcc
     7381 gtagaaagtg aactgggcta taaattgccg caaagtttta ttgaattgat ggcggtacaa
     7441 aacggcggaa tatttgtcaa aaactgtttt ccgaccacgc agagaaattc gtgggcggaa
     7501 aatcatgtgc aaatttgcga ggtatcgggc atcggctttg aaaaagaagg gagtttgtgc
     7561 ggcgaaacag ggcaaaaact ttggctggaa gaatgggaat atccgcccat cggcgtgtat
     7621 tttgccaacg acccgtcagg cggtcatgcc atgtttgcct tggactatcg ggcgtgcggc
     7681 aaagacggcg agccgaaagt ggtgtttgtc gagcaagaat cggattttga aatcgtcgaa
     7741 cttgcccccg attttgaaac ctttatccgc agcttgcggc atgaagatga gtttattgac
     7801 gaggaaatat aaaacggcgg ttgaaaaacc ggaatcatca agggaaaacg ggcgaaataa
     7861 cggataatcg cttgaatccg taaggaaaac ggtttggtgg aacgcgccat ccaagacctt
     7921 tgcaaagaaa aactgtctcc gacagcattg acattattaa cagaacttat caagtttgga
     7981 gctatctcaa atataattcg gttatccttt tgtatccatt aaatcatatg cttcaattaa
     8041 ttgttgttct agctcttgta ccaattttga attgcgaatt cctgacacaa tctcaaattc
     8101 ttctgcatct atgcaaacac ctgcataaat ttcaataaca agggaacgca ataattgaag
     8161 ctcttctctt gttaaagaaa taataatgtc atcacctgtg taattgatta tattcataat
     8221 aattttattt ttgtttgtca aagtaagttt tgcctaaggt tggtctaaat gcagttccac
     8281 catcttttga atttgggtct ctgattacaa ttgctccaga cttatcatcc caaattgctc
     8341 ttatgtgttt ggattgtaat cttcgaattc ccaagaaaaa aatcgtaata agtttgaaag
     8401 tgtcaaatcc caagtttctt ttgagcaata ttctaatatt ttatcaattt cacttttaat
     8461 aatcttatga tcaaactgtt ctaatattaa tgcattagac caaaaaaaac cttctttatt
     8521 acaatgatgg gaaatccatt taggagaaca aatgcaaagt gaaaaaatag atgagccttg
     8581 ttctccttcg attccgatat ccaaatctat ccatctatgg aaattatctg gaatttcggg
     8641 ggtaaatttt tcaaaatcaa tatcatataa atttatgctt tttaaatcca atttaatcat
     8701 tagggctgtc ctagataaat agggaaattc aaattaagtt agaattatcc ctatgagaaa
     8761 aagtcgtcta agccggtata aacaaaataa actcattgag ctatttgtcg caggtgtaac
     8821 tgcaagaaca gcaacagagc ctgacagcat tgtttatacg gattgttatc gtagctatga
     8881 tgtattagat gtgagcgaat ttagccattt ccgtatcaat cacagcacac attttgctga
     8941 acgacaaaac catatcaatg gaattgagaa cttttggaac caggcaaaac gtcatttacg
     9001 caagtttaac ggcattccca aagcgcattt tgagctgtat ttaaaggagt gcgaatggcg
     9061 ttttaacaac agtgagataa aagttcttgt tccattttaa aacaattagt aaaatcgagt
     9121 ttatcttagt tgtccaggac agccccatta tttttataac accgtgaagc cgcacagcag
     9181 tttgaacagt gatacgccgt ttgcgggctt acgagtttat tttcccggcc tgcagtttga
     9241 gcaatacggt gatttcctac ggttaataca aatgtttaca cattgataca tttcatttat
     9301 agttccgcct atttgaaaat agaaaatatg aattcgaccg caagtaaaac cctgaaagga
     9361 ttgtcgctgg tgtttttcgc ctctggattc tgcgccctga tttaccaggt cagctggcag
     9421 aggcttctat tcagtcacat aggtatcgat ttaagttcga ttactgtcat tatttctgta
     9481 tttatggtcg gcttgggtgt gggtgcgtat ttcggtggac gcattgctga ccgttttcct
     9541 tcaagtatca tccccctgtt ttgcatcgct gaagtatcca tcggtctgtt cggtttggta
     9601 agcaggggtc tgatttccgg cttggggcat cttttagttg aggctgattt gcccatcatc
     9661 gctgctgcca atttcctctt attgctgctt cctaccttta tgatgggcgc gaccttgccc
     9721 ttgctgacct gtttttttaa ccggaaaata cataatgttg gcgagtctat cggtatctta
     9781 tattttttca acactttggg tgcggcactc ggatcgcttg ccgccgccga atttttctac
     9841 gtctttttta ccctctccca aaccattgcg ctgacagcct gctttaacct tctgattgct
     9901 gcttcagtat ggctgcgtta cagaaaggat ggatatagtg aacactaaac cgaatactag
     9961 tttgatttat atgctttctt tccttagcgg cttattgagc ttgggtatag aagtcttgtg
    10021 ggtaaggatg ttttcgttcg cagcacagtc cgtgcctcag gcattttcat ttactcttgc
    10081 ctgttttctg accggtatcg ccgtcggcgc gtattttggc aaacggattt gccgcagccg
    10141 ctttgttgat attcccttta tcgggcagtg cttcttgtgg gcgggtattg ccgacttttt
    10201 gattttgggt gctgcgtggt tgttgacggg tttttccggc ttcgtccacc acgccggtat
    10261 cttcattacc ctgtctgccg tcgtcagagg gttgattttc ccgctcgtac accatgtggg
    10321 tacggatggc aacaaatccg gacgacaggt ttccaatgtt tatttcgcca acgttgccgg
    10381 cagtgcattg ggtccggtcc ttatcggctt tgtgatactt gatttcttgt ccacccaaca
    10441 gatttacctg ctcatctgtt tgatttctgc tgctgtccct ttgttttgta cactgttcca
    10501 aaaaagtctc cgactgaatg cagtgtcggt agcagtttcc ctaatgttcg gcatcctcat
    10561 gttcctactg ccggattctg tctttcaaaa tattgctgac cgtccggata ggctgattga
    10621 aaacaaacac ggcattgttg cggtttacca tagagatggt gataaggttg tttatggggc
    10681 gaatgtatac gacggcgcat acaataccga tgtattcaat agtgtcaacg gcatcgaacg
    10741 tgcctatctg ctaccctccc tgaagtctgg catacgccgc attttcgtcg ttggattgag
    10801 tacaggttcg tgggcgcgcg tcttgtctgc cattccggaa atgcagtcga tgatcgttgc
    10861 ggaaatcaat ccggcatacc gtagccttat cgcagacgag ccgcaaatcg ccccgctttt
    10921 gcaggacaaa cgtgttgaaa ttgtattgga tgacggtagg aaatggctgc gtcgccatcc
    10981 tgatgaaaaa ttcgacctga ttttgatgaa tacgacttgg tactggcgtg cctattccac
    11041 caacctgttg agtgcggaat ttttaaaaca ggtgcaaagc caccttaccc cggatggtat
    11101 tgtaatgttt aataccacgc acagcccgca tgcttttgct accgccgtac acagtattcc
    11161 ctatgcatac cgctatgggc atatggtagt cggctcggca accccggtag ttttccctaa
    11221 taaagaactg ctcaagcaac gtctctcccg gttgatttgg ccggaaagcg gcaggcacgt
    11281 atttgacagc agcaccgtgg atgctgcagc acaaaaggtt gtctctcgta tgctgattca
    11341 gatgacggaa ccttcggctg gggcggaagt cattaccgac gataatatga ttgtagaata
    11401 caaatacggc agagggattt aaccgtctta aagggtttca ggcaacgcag gttttaggta
    11461 acgtcctgct agttcaaaaa aaccgcatca cagcagtcgg gacaaaatgg tttaaacatt
    11521 ttgtcccgaa ttcttattcc tatatatagt ggattaacaa aaatcaggac aaggcgacga
    11581 agccgcagac agtacagata gtacggaacc gattcacttg gtgcttgagc accttagaga
    11641 atcgttctct ttgagctaag gcgaggcaac gccgtactgg tttttgttaa tccactatac
    11701 cacgaattac ggtgtaaaaa tttatatgac cttataaaat caaataagaa tcgttatcat
    11761 aacatgattg tatttattgg gtttttttgg gcgttttgcc gatatttacc ttttaatggt
    11821 ttttgaaatt cgctaaaata cgaaattatt gtagaaattt tgttaacgga tttgggtgta
    11881 accatgttgt ccgcttactt tcccgtcttt gtctttatcc ttgtcggtct tgcagccggc
    11941 gtactgttta tcctgctcgg cacaattttg ggcccgaaac gtcactatgc cgaaaaagac
    12001 gcgccttacg aatgcggttt tgaagccttt gaaaacgcaa ggatgaagtt cgacgtgcgc
    12061 tattacctcg tcgccatcct cttcatcctg tttgatttgg aggtcgcgtt tatgctgccg
    12121 tgggctgtcg tgttcaaaga tttgggcgtg tacggcttct ggtctatgct ggtgtttatc
    12181 gtcgttctga cggtaggctt tgtttacgaa tggaaaaaag gtgcgctgga atgggaatag
    12241 aaggcgtttt gaaaaaaggt ttcatcacca ccagcgcgga tacggtgctg aactatatgc
    12301 gtaccggttc attgtggccg gttactttcg gcttggcctg ctgcgccgtg gaaatgatgc
    12361 atgcaggtat ggcgcgttat gaccttgacc gtttcggcat cattttccgt ccgtccccac
    12421 gtcaggccga cctgatgatt gtggcaggta cgctgaccaa caaaatggcg cccgccctgc
    12481 gccgcgtata cgaccagctc gccgagccgc gttgggtatt gtctatgggc tcgtgtgcca
    12541 acggcggcgg ttattatcac tattcttatt ccgttgtgcg cggtgccgac cgcgtcgtgc
    12601 cggtagacgt ttatgtgccg ggttgtccgc cgactgcgga agccctgatt tacggcctga
    12661 ttcagctcca acaaaaaatc aagcgcactt ccaccatcgc gcgtgacgag taaggagagg
    12721 acgatatggc aagcattcaa aatttatacg agaccgtcat cggtgtgctg ggcaatcagg
    12781 caggcaaagt catttcagct ttgggcgaga ttaccgtcga gtgtctgccc gaacactata
    12841 tctcagtcat gaccgcattg cgcgaccatg aagatttgca tttcgagctt ctggtcgatt
    12901 tgtgcggtgt cgattacagc acttacaaaa acgaagtatg gcagggcaaa cgctttgccg
    12961 tcgtcagcca gctgctttcc gttaaaaaca atcaacgcat ccgcgtacgc gtctgggttt
    13021 cagacgacga cttccccgta gtcgaatccg tagtcgatat ttacaacagc gcggattggt
    13081 acgaacgcga agccttcgat atgtacggca tcatgttcaa caaccacccg gacttgcgcc
    13141 gcatcctgac cgattacggc tttgtcggac atccgttccg caaagacttc ccgatttccg
    13201 gctatgtgga aatgcgttac gacgaagagc aaaaacgcgt gatttaccaa cctgttacca
    13261 ttgagccgcg cgagatcacg ccgcgtatcg tccgtgagga gaactacggt ggccaataaa
    13321 ttaagaaact acaccatcaa cttcggcccg caacaccctg cggcgcacgg cgtattgcgt
    13381 atgattttgg agttggaggg cgaaaccatc gtccgtgccg atccgcatat cggcctcctg
    13441 caccgcggta ctgaaaaact ggctgaaacc aaaacctatc tgcaagccct gccctatatg
    13501 gaccgcttgg actacgtttc catgatggtc aatgagcagg cgtattgttt ggcagtagaa
    13561 aaacttgccg gtatcgatgt acctatccgc gcccagtata tccgtgtgat gtttgccgaa
    13621 gtaacgcgca tcctcaatca cttgatgggc atcggttcgc atgccttcga catcggcgcg
    13681 atgaccgcca tcctctacgc cttccgcgac cgcgaagagc tgatggactt gtacgaagcc
    13741 gtttccggcg cgcgtatgca cgcagcctac ttccgtcccg gcggcgttta ccgcgacctg
    13801 cccgacttca tgcctaaata cgagagcagc aaattccgca atgccaaagt attgaagcag
    13861 ctcaacgaat cccgcgaagg caccatgctc gactttatcg atgccttctg cgaacgcttc
    13921 cccaaaaata tcgacacact cgaaaccctc ctgaccgaca accgcatctg gaaacagcgt
    13981 accgtcggca tcggcgtcgt ctcccccgaa cgcgccatgc aaaaaggctt taccggcgtg
    14041 atgttgcgcg gttcgggcgt ggaatgggac gtgcgtaaga cacagcctta cgaagtgtac
    14101 gacaaaatgg atttcgacat ccccgtcggc gtcaacggcg actgttacga ccgttacctc
    14161 tgccgtatgg aagaaatgcg tcaatccgta cgcatcatca aacaatgttc cgagtggttg
    14221 cgtgtcaatc cgggtccggt cattaccaca aaccacaaat ttgctccgcc caaacgtacc
    14281 gaaatgaaaa caggtatgga agacctgatt caccatttca aactctttac cgagggtatg
    14341 cacgttcccg agggtgagac ctacaccgct gtcgaacatc cgaaaggcga gttcggcgtt
    14401 tacatcattt cagacggcgc aaacaaaccc taccgcctga aaatccgcgc acccggcttc
    14461 gcccatctgc aaggcatgga cgaaatggca aaaggccaca tgctcgccga cgtcgttgcc
    14521 atcatcggta cgcaggacat cgtattcggg gaggttgacc gataatgtta tccgcagagt
    14581 ccttaaaaca aatcgacaca gaactggcga aatatcccgc cgaccaacgc cgttccgcca
    14641 tcatgggtgc gttgcgtatc gcccaaaccg aaaaaggctg gctcgccccc gaaaccatcg
    14701 cttttgttgc cgactatatc ggcatcacgc ctgcacaagc ctacgaagtc gccactttct
    14761 acaatatgta cgaccttgag cctgtcggca aatacaaact gaccgtttgt accaacctgc
    14821 cctgcgccct gcgcggcggt atggctaccg gcgaatacct caaacaaaaa ctcggtatcg
    14881 gctacggcga aactacccct gacggcaagt ttacccttgt cgaaggcgaa tgcatgggcg
    14941 catgcggcga cgctcccgtt atgctggtca acaaccacag catgtgcagc tttatgaccg
    15001 aagaagcgat tgagaagaaa ctggcggagt tggagtaggt cgtctgaaac gacgatttaa
    15061 acgtaggtcg gatacttgta gccgacagag tgggtaaaaa ggcaaaatgt cggatttaag
    15121 aatccgccct actgaaatac cgaaatgccg tcattcccgc gcaggcggga atccaccggt
    15181 aagattcggt ttctgaattt aataagacat tgcttaccat tgaggatgga ttcccgcctg
    15241 cgcgggaatg acgacagaca agcaagtggt cgagatccaa caaaaacgat taaaggtcgt
    15301 ctgaaaatat cgatttgata aactagattt tatttcagac gacgttacaa gccggtacac
    15361 aaagacatct taaggtcgtc tgaaacagcg gccgcaaccg atacgaaaac aaacaggcac
    15421 accaaaaatg gctatttacc aatcaggcgt gatttttgac caagtggata ccgccaatcc
    15481 cgattgctgg acattggacg aatacgtcaa acgtggcggt tataccgccc tgcgtaaaat
    15541 cctgtccgaa aacatctcgc aaaccgatgt gattgacgaa gtcaaaacct ccggcttgcg
    15601 cggtcgtggc ggtgcgggct tcccgaccgg tttgaaatgg agctttatgc cccgttcttt
    15661 ccccggcgaa aagtacgtcg tttgcaacac cgacgaaggc gagccgggta catttaaaga
    15721 ccgcgacatt attatgttca acccccatgc cctgattgaa ggcatgatta tcgccggtta
    15781 cgcgatgggc gcgaaagccg gttacaacta tatccacggc gaaatttttg aaggctacca
    15841 acgctttgag gccgctttgg agcaggcgcg tgccgcaggc tttttgggta aaaatatttt
    15901 gggttcggat tttgaattcg aactcttcgc ccaccacggc tacggtgcat acatctgcgg
    15961 cgaagaaacc gcattgcttg aatcgctgga aggcaaaaaa ggccagccgc gctttaaacc
    16021 gccattccct gcttcgttcg gcctgtacgg caaaccgact accatcaaca ataccgaaac
    16081 tttctcctcc gtttcattca ttatccgtga cggcggacag gcatttgccg ataaaggtat
    16141 tccgaatgca ggcggtacca aattattctg tatttccggc catgtcgagc gtccgggcaa
    16201 ctatgaagtg ccattgggca caccgtttgc cgaagtcttg aaaatggcag gcggtatgcg
    16261 cggcggcaaa aaactcaagg ccgttattcc tggcggttcg tccgcgcccg tattgcctgc
    16321 cgacatcatg atgcagacaa atatggacta cgactcgatt tccaaagcag gctcgatgct
    16381 gggttctggc gcgattatcg tcatggacga agacgtgtgc atggtgaaag cccttgagcg
    16441 cctgagctac ttctactacg acgagtcttg cggccaatgt acgccttgcc gagaaggcac
    16501 cggctggctt taccgcatcg tccaccgcat cgtagaaggc aaaggccgca tggaagattt
    16561 ggatttgctg gattctgtcg gcaaccaaat ggcaggccgc accatctgcg cccttgccga
    16621 tgccgccgtc ttccccgtcc gaagctttac caagcatttc cgtgatgagt ttgtgcatta
    16681 catcgaacac ggcggaccga tgaaagagca taagtgggga gggtggtaat ggtggaagct
    16741 aaaattttta ttctatacgg tgcagccaac aaaggtaaga gtacgacact caatacgctt
    16801 tttaatcaga tttgttggaa attttctaaa tttctagtct tttttgaaag acatggaaat
    16861 ggcttagatt ttgttgcagt atttgatcat gaaggtcaga gaattggttt ttattcatct
    16921 ggtgataatg aatacgaggt taggagaaat ttatacaaac tttattcgca taattgtgat
    16981 tttatttttg gcacgtcaag gacacggggt ggtagttgcg atgcagtagg atgttatgca
    17041 gagttattgc atggcgatgt aaatataatt aattggtgtg aaaagtttga gcctacagat
    17101 gaagacaatg agcgtgctgt taaagagtta tttaagtcat ttaaaaatat aataaatgag
    17161 ttatagtttt agttggtttt atattggtta aaagcaaaat gctaaaaatt taactttgcc
    17221 gtcattcccg cgtaggcggg aatccatagt ggaatttaca gaacccgata tttgaaaagc
    17281 agttgccgaa attcaaaaaa tggattcccg cctgtgcggg aatgacggca aggtggcagt
    17341 aaacgtttta aacagtattg attgtcaatg aaactcaaaa ggccgtctga aacccatttt
    17401 tcagacgacc tccataaaag attatttatc aaatacccgt aactaggaac gaaccatgtt
    17461 acaaatcgaa atcgacggca aacaagtatc tgtggagcag ggcgcgacgg tgattgaagc
    17521 cgcgcacaag ctcggtactt atattccgca tttctgttac cacaaaaaac tttccatcgc
    17581 cgccaactgc cgtatgtgtc tggtgaacgt agaaaaagcc ccaaaacccc tgcctgcctg
    17641 tgccacgccg gttacagacg gcatgattgt gcgtacgcat tcggcaaaag cccgagaggc
    17701 gcaggaaggc gtgatggagt tcctgctcat caaccatccg cttgattgtc cgacctgcga
    17761 ccaaggcggg gaatgccagt tgcaggattt ggcggtgggc tacggaaaaa ccaccagccg
    17821 ctacaccgaa gaaaaacgtt ccgtcgtcgg caaagatatg gggtccttgg tttccgccga
    17881 ggaaatgagc cgctgtatcc actgcacccg ctgcgttcgt ttcactgaag aaatcgccgg
    17941 tttgcaggaa attgcgatgg tgaatcgcgg cgaacactcc gaaatcatgc cctttatcgg
    18001 caaaacggtg gaaaccgaat tgtcgggcaa cgtcattgat ttgtgtcccg tcggcgcgct
    18061 gaccagcaaa ccgttccgct tcaatgcgcg tacttgggaa ttgaaccgcc gcaaatccgt
    18121 ttccgcccac gacgctttgg gcagcaacct gattgtacaa accaaagacc ataccgtccg
    18181 ccgcgtgttg ccgctggaaa atgaagcgat taacgaatgt tggctgtctg accgcgaccg
    18241 tttttcctac gaaggcctgt atcacgaaag ccgtctgaaa aaaccgaaaa tcaaacaggg
    18301 cggcgagtgg atggacgtgg attggaaaac cgcgttggaa tatgtccgca gcgcgattga
    18361 atgtatcgcc aaagacggca accaaaacca agtcggcatt tgggcgaacc cgatgaatac
    18421 ggttgaagag ctgtatctgg ccaaaaaact tgccgacggc ttgggtgtta aaaactttgc
    18481 cacccgtttg cgccaacaag acaaacgtct ttcagacggc cttaaaggtg cgcaatggtt
    18541 gggacaaagc attgaatcgc tggcggacaa cgatgccgta ttggtagtcg gtgcgaacct
    18601 gcgcaaagaa cagccgctcc tgaccgcccg cctgcgccgc gccgccaaag accgtatggc
    18661 gttgagtgta ttggccggca gtaaagaaga gttgttgatg ccgcttctct ctcaagaagc
    18721 cgcacatccc gacgagtggg caggccgtct gaaaaacctg tctgccaatg cggaacacgc
    18781 cgttaccgcc agcctgaaaa acgctgaaaa agcagcggtg attttgggcg cggaagtgca
    18841 aaaccatcct gattacgccg ccatttatgc cgccgcgcaa gagctggcgg atgcaaccgg
    18901 cgcggtactg ggtattttgc cgcaagccgc caacagcgtc ggtgcggacg tattgggcgt
    18961 gaactcaggt gagagcgtta ccgaaatggc aaacgcgccg aaacaggcag tcttgctgct
    19021 caacgtcgag cctgaaattg atacggttga cggtgcaaaa gccgtagccg cgttgaaaca
    19081 ggcaaaaagc gtgatggcgt ttacaccgtt tgtcagcgaa acgctgctgg acgtgtgcga
    19141 cgtgttgttg ccgattgcgc cgtttaccga aacctcaggc agcttcatca atatggaagg
    19201 ccgtctgcaa tctttccacg gcgtggtaca aggcttcggc gattcgcgtc cgatgtggaa
    19261 agtgttgcgc gtattgggca atctgtttga cctgaaaggt tttgaatacc acgataccgc
    19321 tgcgattttg aaagacgcgc tggatgcaga aagcctgtcg tccaaactgg acaaccgcag
    19381 tacatggaca ggggagggcg ttcagacggc atcagaccgc ctcgtccgtg tcggcggcgt
    19441 cggtatttat cacaccgatg ccatcgtacg ccgttccgca ccgttgcaag aaaccagcca
    19501 tgccgccgtg cctgccgcgc gtgtaaatcc gaacacattg gcacgcttgg gcctgcaaga
    19561 cggacaaacc gctgtcgcca aacaaaacgg cgcaagcgta tcggttgctg tcaaagccga
    19621 tgccggtttg cctgaaaacg tggtgcatct gccgctgcat accgaaaatg ccgcgctggg
    19681 tgcgttgatg gacactattg aactggcggg agcttgatca tgcaagaatg gttccaaaac
    19741 ctctttgccg caacgctcgg tctgggcgat ttgggcatca ccgtaggctt ggtggtatcc
    19801 gtcatcgtca aaatcgtgat tatcctgatt ccgctgattc tgaccgttgc ctacctgacg
    19861 tatttcgaac gtaaagtcat cggcttcatg cagcttcgcg tcggtccgaa cgtaaccggc
    19921 ccgtggggtc tgattcagcc gtttgccgac gtgttcaaac tcttgtttaa agaggtaacc
    19981 cgtccgaagc tgtcaaacaa agccctgttc tacatcggcc cgattatgtc gcttgctccg
    20041 tctttcgcag catgggcagt gattccgttc aacgaagaat gggtgctgac caacatcaat
    20101 atcggccttt tgtacatcct gatgattacc tcgctgtcgg tttacggcgt gatcatcgcg
    20161 ggctgggctt ccaactccaa atattcgttc ttgggtgcaa tgcgtgcttc cgcacaaagc
    20221 atttcctacg agattgccat gagtgccgcg ctggtgtgcg ttgtgatggt atcgggcagc
    20281 atgaacttct ccgacatcgt tgccgcacaa gccaaaggca tcgcgggcgg ttccgtgttc
    20341 tcgtggaact ggctgccgct cttccccatc ttcatcgttt atctgatttc cgccgttgcc
    20401 gaaaccaacc gtgcgccgtt tgacgtggca gagggtgagt ctgaaatcgt tgccggtcac
    20461 cacgtcgaat attccggctt cgcgttcgcg ctgttcttcc ttgccgaata cattttcatg
    20521 attctgattg ccgcgctgac atcgctgatg ttcctcggcg gctggttgtc cccgttcccg
    20581 caaagttggg gctttatcgg cacaccttcc gcattctgga tgttcgtgaa aatggcggcg
    20641 gtgttgtact ggtacctgtg gatccgtgca accttcccgc gctaccgtta cgaccaaatc
    20701 atgcgtttgg gctggaaagt gctgattccg atcggcttcg cctacatcgt ggttttgggc
    20761 gtgtggatga tttcaccgct gaatttgtgg aaataagttt cagacggcat cttgaggccg
    20821 tctgaacaaa gcgattttga atacctaacg aaatccctgt tttgagggaa cataatatgg
    20881 ctaacttagt aaaaaccttt ctgcttggcg aattggtaaa aggtatgggc gtaacgctca
    20941 aaaacttttt cgcccgcaaa gacacgattt attttcccga agagaaaacg ccgcaatccg
    21001 tgcgtttccg cggcctgcac gcgcagcggc ggtatccgaa cggtgaggaa cgctgcattg
    21061 cgtgtaagtt gtgcgaggcg gtgtgtccgg caatggcgat caatatcgaa tcggaagaac
    21121 gcgaagacgg cacccgccgc accaagcgtt acgacatcga cctgaccaag tgcatcttct
    21181 gcggcttctg cgaagaggcc tgcccaaccg atgcgattgt ggaaacgcat atttttgaat
    21241 accacggcga gaaaaaaggc gacttgcaca tgaccaagcc gatcctcttg gcaatcggcg
    21301 acaaatacga agccgaaatc gccaaacgca aagccgctga cgcgccgtac cgttaaggag
    21361 cagacgaatg actttttccg cgattctgtt ctatatcctt gccaccatcg tcttatacgg
    21421 cgcgctgcgt accgttaccg ctaaaaaccc tgtccacgcc gctttgcatc tggtgctgac
    21481 cttctgcgtg agcgcgatgc tttggatgct gatgcaggct gagtttttgg gcgtgacgct
    21541 ggtggtggtt tacgtcggcg ccgtgatggt gttgttcctg ttcgtcgtga tgatgttgaa
    21601 catcgacatt gaagaaatgc gtgccggttt ctggcggcac gcgcctgttg ccggtgtggt
    21661 cggcacattg ttggcggttg cgctgatcct gattctggtc aacccgaaaa ccgaccttgc
    21721 cgcatttggt ctgatgaaag acattcctgc cgattacaac aatatccgcg atttgggcag
    21781 ccgtatttat accgactatc tgttgccgtt tgaattggcg gcggtattgc tgttgttggg
    21841 tatggtggcg gcgattgcgc tggttcaccg taaaaccatc aatccgaaac gtatggatcc
    21901 tgccgaccag gttaaagtac gcgccgacca aggccgtatg cgtctggtga aaatggaagc
    21961 ggtcaaaccg caagtcgaat ctgccgaaga aagcgaagtt tcagacggtc tcaagccgga
    22021 aggggagggc aaagcatgat taccttgacg cattatctgg tattgggcgc gctcctgttc
    22081 ggtatcagcg cgatgggcat ctttatgaac cgcaaaaacg tgctggtctt gctgatgtcc
    22141 atcgagctga tgcttttggc ggtgaacttc aactttatcg ccttctcgca acatttgggc
    22201 gataccgccg gacagatttt cgtattcttc gtactgaccg ttgccgctgc cgaatctgcc
    22261 atcggtttgg cgattatggt attggtgtac cgcaaccgac aaacaatcaa cgttgccgat
    22321 ttgaacaaac ttaaaggttg atttggaatt tttaaagaaa aaaggagata gataatgttt
    22381 gatattgctg ctgttggatt aggtgcagca ggagttagct taatcaaaca gttacaggta
    22441 aaaactcttg tttgccatat caaggcactt tggtctccac acgcccatat atgcataaat
    22501 tgtggattag tatgagtgaa agagaatgtt tacaatttca agggctcatt ggcagccatt
    22561 gggctgtatg gcgggtaatt gggtaaaaca atgggttttt gaaaatttta gaatttcaga
    22621 aagtggagag tgattatgtc attttcaatt gctcttccat tggtatatct gtttattggc
    22681 attttgattg ggaaaacccc ttttagaaaa attaaaggca ctttttctgt aatattgagc
    22741 agatggatta tcccttttgt tattgtctat aacataacga catatcgtga tggtatgcag
    22801 tatgttatgt tatggatgat tatttcgatg gggttgatta tcctaatcgg gaaaagagtt
    22861 gataaagatc ctgtttggaa tttgtgtttg tgctatttga acatcggatg gttggggctt
    22921 cccatagttg caaccttgtt tggagatgag gcggcgcaag tgcttatttc ggcatacgtg
    22981 ggaagttctt tattcggaaa ttcggtcggg gtcgggttgt tattgaataa tagtaatttc
    23041 atatccggat tgaaaaagac tttaaaatcc cctcccgttg ttgcattggt aataggaatg
    23101 ttcggtattc cgctagggca ttttgtagca gattattttg gggaagttta ttttttctcg
    23161 aaaatagcaa tgggaatatt ggggatggtg atactcggta tttggctggc tgagataaaa
    23221 ctaaatttga atgatttgaa gaaaagtatt aaaccgtttc taataaaaaa cattttattt
    23281 atagggattg tttttctttt tatccaaata gctgcatatt ttgacttgaa gttgattctt
    23341 gaaaaccaaa aaacattgta tttaataccg ttgctgccgc ctgctgccaa tattattgtg
    23401 ttggaaacgg catatttgaa aacagggcgt tcggcttcta tgattgcgta tggtacgatt
    23461 tttagtttaa tcgcaatcag catttatatt ttactggtgc aaatttaaat gaacgacatg
    23521 actttatatc tcatcatcgc cctcgtgcct ttggcaggct cgctgattgc gggtttgttc
    23581 ggcaacaaaa tcggacgtgc cggcgcgcat acggttacga tactcggcgt ggctgtgtcc
    23641 gccgtgctgt cggcttatgt gctgtgggga ttcctcaatg gcagccgtgc caagtttgac
    23701 gaaaacgtct atacctggct gacaatgggc ggcttggatt tttccgtcgg cttcttggtt
    23761 gatacgatga cggcgatgat gatggtcgtg gtaacgggcg tgtcgttgat ggtgcatatc
    23821 tacaccatcg gctatatgca cgacgaaaaa gtcggctacc aacgcttctt cagctacatt
    23881 tctttgttta cattcagcat gttgatgctg attatgagca acaacttcat ccagctcttc
    23941 ttcggttggg aagcggtggg tttggtgtcg tatctcttga tcggtttcta tttcaaacgc
    24001 ccgagcgcga catttgccaa cctgaaagcc tttttgatca accgtgtcgg cgacttcggc
    24061 tttttgctcg gtatcggctt ggtgcttgcc tatttcggcg gcagcctgcg ctatcaggac
    24121 gtattcgcct atctgcccaa cgtccaaaat gccaccatcc agcttttccc cggcgtggaa
    24181 tggtctttga ttaccgtaac ttgtttactt ctgtttgtcg gtgcgatggg taaatcggca
    24241 caattcccgc tgcatgtctg gctgcccgat tcgatggaag gcccgacccc gatttccgca
    24301 ttgattcacg ccgcaaccat ggttaccgcc ggtctgttca tggtatcgcg tatgtcgccg
    24361 atttatgaga tgagcagcac tgcgctgtct gtcatcatgg taatcggtgc gattactgct
    24421 ctgtttatgg gtttcttggg cgtgattcaa aacgacatca aacgtgtggt tgcgtattcc
    24481 accctgtcgc aactgggcta catgaccgtg gctctgggcg cgtctgccta ttccgtggcg
    24541 atgttccatg tgatgaccca cgccttcttt aaagccttgc tgttcttggc ggcgggcagc
    24601 gcgattatcg gtatgcacca tgaccaagat atgcgccaca tgggcaatct gaaaaaatac
    24661 atgccgatta cttggctgac catgctgatc ggtaacttgt cgctgatcgg tacgccgttc
    24721 ttctccggct tctattccaa agattcgatt atcgaagcgg cgaaatacag caccctgccg
    24781 ggcagcggct ttgcctattt tgccgtcctc gccagcgttt ttgttactgc gttctacgca
    24841 ttccgccaat actttatggt gttccacggc gaagagaaat ggcgcagctt gcctgaacat
    24901 catgacgatc atcatggcga agaacatcac agcttgggca aaaacgacaa tccgcacgaa
    24961 agcccgttgg ttgttaccct gcctttgatt ttgcttgcca ttccgtccgt catcatcggc
    25021 taccttgcca tcgagcctat gctttacggc gatttcttca aagatgtgat tttcgtcaat
    25081 accgacgcgc atccgaccat gcacatcatg aaggaagagt tccacggcgc attggcaatg
    25141 gtgtcgcaca gcctgcattc gcccgtactc taccttgcta tcgcaggcgt gttgagcgca
    25201 tggcttttgt acgtcaaact gccgcacctg ccagcgaaaa ttgcacagac gttccgtccg
    25261 atttacgttt tgtttgaaaa caaatactac ctcgacgccc tgtatttcaa cgttttcgcc
    25321 aaaggcacac gcgcattggg taccttcttc tggaaagtcg gcgataccgc cattatcgat
    25381 aacggcatcg tcaacggctc tgccaaactg gtcggcgcga ttgccgcgca agtgcgtaaa
    25441 gcccaaaccg gctttatcta cacctacgcc gccgctatgg tattcggcgt attggtactg
    25501 ctcggcatga ccttctgggg attgttcaga taaaggcgga gtttcagacg acctgttcat
    25561 agttttgtag aggtcgtctg aaaagtttga gaagtgggca ttaagtcaaa gggtggaaca
    25621 aaatggtacc caacaggcgt gaaatagcca acatgcaaat tatctgtttc ctaaattttt
    25681 taggcaatct caacaaatat agaggagtca aaagggatga cacagttatt tttacattca
    25741 gatacaccaa atgagaagga actgatttca atatatgaga aagctgtttc agaggcagta
    25801 gagctgtata ttttctctgc gtatctcact cattgggatg taaaaaataa gctcaatagc
    25861 aaattgcaag agtttaaatt tatttttgga caagatttcg gattgtctaa aaaagaggct
    25921 attcggaaag tgttgaaatg gcttccgtcc catttgaaat tcacactgat ggtagctcaa
    25981 ggcattcagg gttttcatcc taaagctgta ttttggaaga atgataagaa tgaatattat
    26041 gctttaatcg gttcttcaaa tttgactcat gctgcgttta atagcaatta tgaagcaaat
    26101 attttgacta aaatttccga gcaggatttt ataaaagtca aatcttgggc tgatgaaatt
    26161 gcgatgaaat ctatcccagt atcggaagat tggcttgagg agtatcagga agctgaaatt
    26221 aattataaga aatcaactgt tagccaatca ttgatggata agttatttat ggaaatgcca
    26281 aattataatc aagaactgat tgcagcacgg agaaaacaga tgagaaacca tcaaactgtg
    26341 tgtaatcaat taaaaagtct tattaagcaa tgtgctgcag gaaagataga caatgatgag
    26401 ttttatgtgg aatttaataa attatggtct tggaaaagcg aaaataaagg agaaggggta
    26461 ggtaatcgat ttcaagatca aacgtggaaa aggaccggaa agtcttcaga ttttagaaaa
    26521 ttatgcattg ctatccaatc agtttttgat gcaccacttg ctgagagaga taatgttgtt
    26581 gccaagcaaa ttgattggct aaaagaatgt ggagtttcca ctcgtggttc agttttttct
    26641 gaaatgcttt gtcaagaata tccagataga tatccagtgt taaacgctcc tattaaaaaa
    26701 tttttagaaa aaaataaatt taagtctgca aaaggagcaa gtgaaggctc tagatatatt
    26761 gatttaagta tgaagttaag agctttacta gcaatgcagt cagaaataaa aaatttggct
    26821 gaattagatg ttttagtgca ggcagaatat cgcgatagta cagatattga ttgggagtga
    26881 gtaaagaggg gagagagtat tcatcccttt ttcagacgac ctcctgaaac gtcgtctgac
    26941 aaactaaccc gcactacgat atttttattt taaccacagg ttaaccacta tgttttccaa
    27001 ctacctactc agcttggcaa tatggatacc catcgccgca ggtgtgctgg ttttgtcgac
    27061 cggtaaggac agccgtgcgc cgctggcgcg tgtgcttgcc tttatgggtg cgcttgccgg
    27121 tttcttggta acgctgcccc tgtttaccgg tttcgaccgt ttgagcggcg gctatcaatt
    27181 taccgagttc cacgagtgga ttccgctgct gaaaatcaac tatgcattgg gcgtggacgg
    27241 tatttcagtg ctctttatca tcttgaatgc gtttattacg ctgctggtgg tattggccgg
    27301 ttgggaagtc attcagaaac gtccggcgca gtatatggcc gctttcctga tgatgtcggg
    27361 tttgattaac ggcgcgtttg ccgctcagga tgcgattctg ttttatgtgt tctttgaggg
    27421 tatgctgatt ccgctgtacc tgattatcgg tgtatggggc ggcccgcgcc gcgtctatgc
    27481 gtcggtcaag ctgttcctct atacgctgat gggttcactc ttgatgctgg ttgccatggt
    27541 ttacctgtac tatcaaacag gcagcttctc tattgtcgat ttccaaaaca tcaaacagat
    27601 tccgttgggc gtacagcagc ttttgtttgt ggcattcttc ctgtcatttg ccgtaaaagt
    27661 gccgatgttc cccgtacaca cttggctgcc ggatgcccac gttgaagcac cgaccggcgg
    27721 ttcgatggtg ttggctgcga ttacgctgaa actgggtgcg tatggtttct tgcgctttat
    27781 cctgccgatt atgccggatg cggcacgcta ttttgccccc gtgatcatcg tattgagtct
    27841 gattgccgtg atttatatcg gtatggtggc tttggtgcaa accgatatga aaaaactggt
    27901 ggcgtattcg tccatcagcc atatgggttt tgtaacgctt gggatgtttt tgtttgttga
    27961 cgggcagttg gacgactggg cattgaaagg cgcggtcatt cagatgattt cgcacggttt
    28021 cgtgtcggcg gcgatgttta tgtgcatcgg tgtgatgtac gaccgcctgc acacgcgcaa
    28081 tatcgccgat tacggcggcg tggtcaacgt gatgcccaag tttgcggcgt ttatgatgtt
    28141 gttcggtatg gcgaacgccg gtttgccggc gacttccggc ttcgtgggcg agtttatggt
    28201 gattatgggc gcggttaaag tgaatttctg ggtgggcgcg ttggcggcta tgacgctgat
    28261 ttacggcgcg tcttataccc tgtggatgta caaacgcgtg attttcggcg agattcgcaa
    28321 tccgcacgtt gccgatatga aagacatcaa ttgccgcgaa tttgcggttt tggcggtttt
    28381 ggcggcggct gttttgggta tgggcctgta tccgaacgcg tttatcgaag tggtacatca
    28441 ggcggcaaac gatttgattg cccatgtggc acaaagcaag atttgaggtg tgtaaatgaa
    28501 ctggtctgat ttgaatttaa tgcccgccat gcccgaaatc gtgctgctgt cgctgctggt
    28561 gttattgttg ctggcagact tgtgggtcag tgatgacaaa cgccgttgga cgcattacgg
    28621 cgcgttggca acggtggcgg ttacggctgt ggtgcagctt gccgtttggg aacagggcag
    28681 cacgtcttcg ttcaacggca tgtatattgc agacggtatg tcgcgtttgg caaaaatggt
    28741 tttatatgcc ttgacctttg ccctgtttgt ctatgccagg ccctacaacc aagtgcgcgg
    28801 tattttcaaa ggcgagtttt acaccctgtc gctgtttgcc ctcttgggta tgggcgtgat
    28861 ggtgagcgcg gggcattttt taactgccta tatcggtttg gaactcttgt cgcttgccct
    28921 ttacgccctg attgccctgc gccgcgattc cggctttgcc gccgaagccg ccttgaaata
    28981 ttttgttcta ggcgcgctgg catccggcct gctgctctac ggtatttcta tggtttacgg
    29041 cgcaaccggt tcgctggaat ttgccggcgt gcttgcctct tccttcaatg aagaagccaa
    29101 cgaatggctg ttgaaactgg gtctggtgtt tatcgtcgtc gccgttgggt tcaaactcgg
    29161 cgcggtaccg ttccatatgt gggtgcccga cgtgtatcac ggcgcgccca cttctgttac
    29221 cgccctagtc ggcactgccc cgaaagtcgc cgccgtcgtt ttcgctttcc gcatcctcgt
    29281 taccgggctg ggaaccgtgc atcatgactg gtctctgatg tttgccctgc ttgccgccgc
    29341 ctcgctgctg gtcggcaacc ttgccgccat catgcagacc aatatcaaac gtatgctcgc
    29401 ctattccacc gtatcgcata tgggtttcat cctgttggcg tttatggcgg gcgcggtcgg
    29461 ctttgcggcg ggtctctatt acgccattac ctacgcgctg atggcggcgg cagggttcgg
    29521 cgtgttgatg gtgttgtcgg atggggacaa cgagtgcgaa aacatcagcg atttggcagg
    29581 gctgaaccaa caccgcgtat ggcttgcctt tttgatgtta ctggttatgt tctctatggc
    29641 gggcattccg ccgctgatgg gtttttacgc caaatttggc gtgattatgg cactcttaaa
    29701 acaaggctat gtttggttgt cggtgtttgc cgtcgtgatg tcgctgattg gcgcgttcta
    29761 ctacctgcgc gtggtcaaag tcatgtattt tgacgaatcc ggccgcgccc gtctcgccgc
    29821 cggcggcaac aatgccgcaa aattcctctt gagcgtcaac gcgctgctgt tggtgctgtg
    29881 gggcattatg ccgcaaaccg ttatcgactg gtgcgccaag gcgttggaaa acacgctgta
    29941 agccgccgca acggcagccg tgtcagaggc tgccgttttt gttaagatat gccgttccgc
    30001 aatgcagttc agacggcatc gccgccgaca acgcccaaac agaaagccca ccatgaccgc
    30061 atccatgtac atccttttgg tcttggcact catctttgcc aacgccccct tcctcacgac
    30121 cagactgttc ggcgtggccg cgctcaagcg caaacatttc ggacaccact tgatcgagct
    30181 ggcggcaggt ttcgcgctga ccgccgttct tgcctacatc ctcgaatccc gtgcgggagc
    30241 ggtacacaat cagggttggg agttctacgc caccgtcgtc tgcctgtacc tgatttttgc
    30301 gtttccctgt ttcgtgtggc ggtatttttg gcacacgcgc aacagggaat aggcaggcat
    30361 aggaatgccg tctgaaaccc tttcagacgg catttgtttc attcaagtgc aggccggcat
    30421 cgctgtgccg gcacgtttca gccggcgata tacgccggtt ttaatatttg cgggcgactg
    30481 caaattctgc caactgccgc aggcgcaggg ctttgtcgcc gaagggttcg agcagcgcga
    30541 ccgcttcggc aaccagtttg tgtgcgtatg agcgcgccgc ttccaagccc atcagtttca
    30601 cataagtcgg cttgtcgttg tctgcgtctt tgcccgccgt tttgcccaaa gtcgccgtgt
    30661 ccgcttcaca atccaacaca tcgtcaatga cttggaacgc cagccccagt tttgccgcat
    30721 aatcgtccaa taccgccaga ctgtcttcag acagattcgg gcaggacatc gcccccaata
    30781 aaaccgccgc acggattagc gcacccgttt tcaggctgtg catctgttcc aaatcggctt
    30841 gaaccatttg tttgccgaca ttcgccaaat cgattgcctg accgcccgcc atgcccgcgc
    30901 tgccgcccgc tttcgccaac accgacaaca ttgccaactg gcgtgctgcg ggcagttctg
    30961 tcggacggct taacacgtcg aaggcttggg tttgcaaagc gtcgccgacc agtagcgcgg
    31021 tggcttcgtc gtattgtata tggcaagtcg gtttgccgcg ccgcaggctg tcgttgtcca
    31081 tcgccggcat atcgtcgtga accaaagaat agacgtggat catttcgatt gccgccattg
    31141 cctgtccgac cgcatccgcc acggctccgc ccaattccga agccgccagc accagcatcg
    31201 gacgcagacg tttgcccccg tccaaagccg cataacgcat ggcttcgtgc agtgtgtgcg
    31261 gtatttcccc ctcagacggt aaaaaccgtt caagcagcag ctctgtttgc gcctgcgccc
    31321 taagctgcca tgctttcaaa tcattcgtcg gattcaaggt tcaactcctt cagcccgtcc
    31381 gcatccaaaa cctgtaattt ctgttcgact tgtgccagtt tggtttggca gtacctgacc
    31441 agctcgttgc cttcctgata ggcggcaagc gcgtcttcca agggcatttc gccctgcata
    31501 gactgcgtca gcgattcgag gcgcgacaag gcttcttcaa acgatttcgg ggcgtttttc
    31561 ttcatcgtat ttccttttcg gttgaaaccc cgccctttag ggcggcagga tcagacttta
    31621 tttgggaggg gtgtaaccct ttccaaatca gggcaataca tagggcggtg ctttatgtgc
    31681 cgtcctgtgt gttggaacat agtttcggat gttccggtaa aaagcggatt gtagcatttt
    31741 tgaaaaacgg atgccgtctg aaacccgaat ccggcttcag acggcatttt ttccgcccag
    31801 gcggcaaggc gttacccggg cagttcgtcg gtgatgccct gcaaaaaggc gaggcgttcg
    31861 gggcttgccg ccccggtttg cgcggcggct ttgaaggcgc agccgggttc ggcgcggtgg
    31921 gtgcagttgt ggaagcggca ttgcccgaca aggtggcgga aatcggggaa atagcgcggc
    31981 aaatcggcgg cttggaggtg gtgtaaacca aattcttgca aacccgggga gtcgatgagt
    32041 tgggtttcgc cgttcaaatc ataaagccgg gcgtgggtgg tggtgtgttt tcccgagtcg
    32101 agtgcggcgg aaatgtcgcc ggtgcgggcg gtttggctgc ccaaaagggc gttggtcagg
    32161 gtggatttgc ccataccgct ctgcccgagc aggatgttgc tgtgcccttg cagggcgggg
    32221 cgcaggctgc cggcgttttc cagtgcgcgg gtttcgatga cgggataacc cagcgtttcg
    32281 tagaatttga gtttttcgcg ccaaagggcg gtttcgggca ggtcggcttt gttcaggacg
    32341 atgacggctt caataccggc ggcttcggcg gcaagcaggg cgcgttgcag cagccgcacg
    32401 ctcggactcg ggacggcggc ggttacgatg aggagttggg taacgttggc ggcgatgagt
    32461 ttggttttcc acgcgtcttg gcggtagagc aggctttggc gcggtaaaaa atcttcaatc
    32521 acaacttgtt cggcgttgac ggggctgatg cggacacggt cgccgcaggc gaaatcgacg
    32581 cgttttttgc gggtgctggc ttcgtaggtt gtgccgtcgg gcgtgcgcac gatgtagcgg
    32641 cggccgtagc tggcggtaat ttgggcggtg tcgttcatgg tttctttggg gttgggtgtg
    32701 gaaatgccgt ctgaaaacgg gtgttcggac ggcatcggtt cagtcgtgct gccactcgac
    32761 gtgttcgttg aggaagccgc cgctctggtg cgcccagagt ttggcgtaaa gcccgcgttt
    32821 ttcgaggagt tcggcgtgta tgccttcttc gatgatgcgg cctttgtcga ggacgacgag
    32881 cctgtccatt gcggcgatgg tggagaggcg gtgggcgatg gcgatgacgg ttttgccgtc
    32941 catcattttg tcgaggcttt cctggatggc ggcttcgact tcggaatcga gcgcgctggt
    33001 ggcttcgtcg agcagcagga tgggcgcgtc tttgagcatc acgcgggcaa tggcgatgcg
    33061 ctggcgttgc ccgccggaga gtttcacgcc gcgttcgccg acgtgcgcgt catagccgcg
    33121 ccgccctttg gcatcggaaa gttcggggat gaagccggcg gcttcggcgc gttcggcggc
    33181 ggaaaccatt tcggcatcgg tcgcgtcggg gcggccgtaa ataatgttgt cgcgcacgga
    33241 acggtgcagc agcgaggtat cttgcgtgac caaaccgatt tgggcgcgta aagattcttg
    33301 ggtaacgccg cttatgtcct gcccgtcgat cgaaaccgtg ccgctttgcg gttcgtagaa
    33361 gcgcaaaagc aggttgacga tggtggattt gcccgcgccg ctgcgtccga tcaagccgac
    33421 tttttcgccc gggcggatgg tgaggttgaa gccgttgagc agcggtttgc cggcttcgta
    33481 gcagaaatcg atgtgttcaa atttgatttc gccttgcgac actttcagcg gcagggcgtt
    33541 cggcttgtcg aggatggtgt gcggtttgga cagggttgcc atgccgtcgc cgacggtgcc
    33601 gatgttttca aacagccgcg cggattccca cataatgtat tgcgacagcc cgttgacgcg
    33661 caacgccatc gcggtggcgg tggcgaccgc gcccacgccg acctgcccgt tgtgccagag
    33721 ccagatgccc agtgcggcgg tggagagggt cagggaggtg ttgacgatga agctgcacga
    33781 atgcagcagc gtcgccagcc gcatttgggc gcgcaccgta accataaatt cttccatcga
    33841 ctgcttggca taggcggctt cgcgcgcgcc gtgggagaag agtttgacgg tggcgatatt
    33901 ggaataggca tcggtaatgc ggccggtcat cagcgagcgg gcatccgcct gccatgcggc
    33961 ggtttgcccc aatttgggaa tcagcaggcg catcaccgaa gcgaaaccga caatccagcc
    34021 gataaagggc agcagcagcc atgagtcgag cgaggcgaga atcacgccgg aggtaatgaa
    34081 atacaccgac acataaacga ccatatcggc aaccgtcatc accgcgtcgc gcaacgccag
    34141 cgcggtctgc atgactttgg cggacacgcg tccggcaaat tcgtcctgat aaaaaccgag
    34201 gctttggttc agcatcaggc ggtggaagtt ccagcgcagg cgcataggga acacgccctg
    34261 aagggtttgc aggcgcacgt tggacgcggc atacgcccac acgaccgaaa acaccatcat
    34321 cgccgccatt gccgccagtt cccaaccttt ttcggcaaac agttcggcgg gcgcgtattt
    34381 gccgagccac tccacgattt tgcccataaa ttgaaaaacc agggcttcca taatgccgat
    34441 gccggcggtc agcgcagcca gggcggctat ccatttccgc acgccggcca tgctgctcca
    34501 gacaaaccgc cacaagcctt tttctggcgt tttcggggcg gcttcgggat aagggtcgat
    34561 tcgggactcg aaccaggaaa atattttgtt caacattgtt ttcgatttcg gtaaaacagt
    34621 ttcagacggc atcaaacaca atgccgtctg aaaggaagga caataacgcc attttacggg
    34681 aaaagccgtc gggaagacag cgcgaggcgg aaacgcaggg tttcgtcagg gcaaacgccg
    34741 cgccgccttc agacggcatt atttcagcag gtttttcaaa gcaaggcgca cgccttcgcc
    34801 cacgtccgtc cctttcggaa cgcctttgac cgccgctttt gcttcgcgtt cgctgtaacc
    34861 cagtgcaagc agtgtgctga cgatgtcttc cgtttcgtcg gcggcgggtg cggcggcaaa
    34921 cagcccgtcc gttaccgtat gcgcgaccag cttgccgcgc agttccaaga ccatacgttc
    34981 ggcggttttt ttgccgattc ccggcgcgga agacaggcgt ttgacatctt cttctgcaac
    35041 cgcccgcgcc agctcgtctg ccgtcatcgc tgacaaaatg cccaaagccg ttttcgcgcc
    35101 gatgccgccg accttaatca gttggcggaa ggtcttgcgt tcttccgcag tggcaaaacc
    35161 aaataaaaga tgtgcgtctt cccgaatgat aagctgggta aacagttgta cgctttcacc
    35221 cacgggcggc aggttgtaga aggtctgcat cgatacgtcg gcctcatagc cgacaccgtt
    35281 gacatcgatg acgatttgcg gagggttttt ttcaaccagt ttgccggtca gtctgctgat
    35341 catgtatgaa ggatcctgaa gtgtcgggtg caaaatgccg tctgaaaccg gttcgggctt
    35401 cagacggcac ggattgtatc aaattcagtc gtcgcggcgg gaggaaatca cgcggccggt
    35461 acgggcatcg acaacgactt tgtattcctg tccgtttttg acgatttcga catcatagtg
    35521 cggacggccg ttgtcgtgtt cgagatcgat gtcggtgatt ttgccgccga cacgcgccaa
    35581 cgctgctttt tcggcttggg cgcggctgat gattttgtct tgtttgctgt gttggtgtgc
    35641 ggcgtgtccg tggtcgtcat cgccgtgtcc gtcgtggtgg gcgagtgcgg gggcggaaat
    35701 gcccatcagt gcggttgcgg cggcggtcaa gagaaggtgt ttgatgttca tattttgcct
    35761 ttgtaaatcg tgggttggaa aatgtggata ttaataaggt atcaaataac cgtcagccgg
    35821 cagtcaatac cgcccgaacc ataccgcgcg cctgagcttc ggcttcggcg gcgcgttcct
    35881 gcgaggaaaa cggccccatt ttgacgacat attcgtaatg gcgtttttca accgataggt
    35941 tcgggtttga tgccgatgaa gccaggtttt gggcggcttg gttcagatag gcttgtgctt
    36001 cgtgttccgt accgaaagat ttcaagtcga tgaagatgtc tttgttttcg gcaaccagtg
    36061 cggattggcc cgggacgatt tgttcgattt tgacgtgcgc cgtcccttgg ctgacaaagc
    36121 ccaatttttg cgcggcggct ttggatacgt cgatgatgcg gttgccgtgg aagggaccgc
    36181 ggtcgttgac gcggacgatg acgcttttgc cgtttttggt attggttacg cgcacatagc
    36241 tggggatggg cagggttttg tgggcggcgg taaaggcgtt catatcgtat cgttctccgc
    36301 cggaagtttt gcgcccgtga aacctgccgc cgtaccacga ggcgttgccg gtttgcgtga
    36361 attcggcgac ttggtttttc ggcgtgtagc gttttccggc gactttgtag ctgcggttgg
    36421 cggaggcgtg cagtttttct gccttgacca ctgcgtcggc ggatgccgtc tgaagggagt
    36481 gtgtgccgaa tgcggcggtg agaaggaaaa gggtttttcg ggttaaagtc aaaacgtgtt
    36541 ccgttcttga gttgaagacg aatgggcatc atgcccgccg gatacgttcc gaaccgccgt
    36601 acagtgcgga cggcggttcg gaatgtgtcc ggataggttt tcagacggca tgaacttgcg
    36661 ttcaaacgcc gcctgcgtaa ccgtgttgcc gccacgcttc aaagagaatc acggcaacgg
    36721 tattggaaag gttcatactc cggctgccgg gctgcatcgg caggcggatt ttttgcgcgg
    36781 cgggcaggct gtcgaggatg tcggcaggca gtccgcgcgt ttccggcccg aacagtaaaa
    36841 catcgccttt ctgaaacgcg gtttcatcgg ggcgcgccgt gcctttggtg gtcagggcga
    36901 aaatgcgcct gcctgcgagt gccttgaggc agtcgtcgaa gttttcgtgc accgtcaggc
    36961 tggcgaattc gtggtagtcg agcccggcgc gtttcatttt ggcggaatcc aatgggaagc
    37021 cgagcggttt gacaaggtgc aaatccgcgc cggtattggc gcacaggcgg atgatattgc
    37081 ccgtgttcgg cgggatttcc ggttggtata aaacgatggt aaacataaat atcaatcact
    37141 tataggcgcg taaccttgcc acaaggcgga tggggtgtca aaaaatttag ttattttttc
    37201 attggcgtgc gtgccagcgt ccagcagcag attcggtttg cgcccgattt tttcagcgtc
    37261 tttgccagtt cgtccagcgt cgcgccggtg gtaaagacat cgtcgattaa caaaatatta
    37321 cagttttccg gtatcggtgt gcggatttca aaggcgtttt tgatgtttcg ccgccgttcg
    37381 ccgcctttga gcgtgctttg cggcgggcgg tggtgtcgga aaacggtgtg tcggggcagt
    37441 atctgccagc cgtagcgttg tgccagcagc ccgacgatgc tttcactttg gttgaacccg
    37501 cgttgcagca gccgctccct gcttagcggt acgggcagga cgaaatcgaa acattcgtct
    37561 gcaagccggt cgggcggatt ctgcatcatc aggtctgcca gcggctgcac catgctcaaa
    37621 tcagccaagt gcttcagcgc gtgtatcata ttgctgacgg gcggttcgta atgcagcgaa
    37681 gcccacatcc ggtcgaatgc gggcggtttt ttctgacagc cgccgcacac cgcgccgcct
    37741 tgaacgtgca tgaaacacag ggggcagctg tttgccgcgt cggtgcggta tgccgccaaa
    37801 tcgtcgcggc agccggcgca gatgccgtct gaaacgccgg acgaaccgtg gcataatacg
    37861 caacgcctga tagtgggcgc gtctgcgatg cgccgccaac aagagagaaa atccatgcct
    37921 gatgccgtca aaaaagttta cctgatacac ggttgggggg cgaaccgcca cgtgttcgac
    37981 gatttgatgc cgcgcctgcc tgcaacgtgg ccggtgtccg ccgtcgattt gcccggacac
    38041 ggcgacgcgc ccttcgcgca acccttcgat attgaggcag ccgccgacgc tgttgccgca
    38101 caaatcgata cgcccgccga cattctcggc tggtcgctcg gcggattggt cgcgctgtat
    38161 ctggcggcgc gccatcccga caaagtccgt tcgctctgcc tgacggcgag tttcgcacgg
    38221 ctgacggctg acgaagacta tcccgaaggg cttgccgcgc ctgcattggg caaaatggtc
    38281 ggcgcgttcc gaacggatta tgccaaacat atcaaacagt ttctacaact ccagcttttg
    38341 cacacgcctg atgcggacgg aatcataggc agaatcctgc ccgatttggc gcgctgcggc
    38401 acgccctccg ccttacagga agctttggac gcggcggaaa gggcggatgc gcggcatttg
    38461 ttggacaaga tagatgttcc ggtactgctg gtgttcggta gcaaagacgc gattacgccg
    38521 ccgcgcatgg gcgagtatct gcaccgccgt ttgaaaggca gcaggctggt tgtgatggaa
    38581 aaggcggcgc atgcgccgtt tttgagccat gcggaagcgt ttgccgcgct gtaccgcgac
    38641 tttgtcgaag gggtttgaca tgaatccgca ggacaaatgc tggcaggttc accgccatct
    38701 cgccgaatat gccgaccaac gcctgacact cgtccgcaac gcgcccaagt atatcctgct
    38761 tgcaggtgcg gatgcggaca tcagccgcag cctgctggcg aaacgctatc cgcaggcggt
    38821 atttgaagaa tacgattccc gtgcggattt tttggcggct gccgctgccg cccgcaaagg
    38881 cggtttttgg caaaggttta cgggtaaggg cgtggtgcaa cactgccaat ccccgatcgc
    38941 gccgctgccc gaagcgtgtg ccgatatgtt gtggtcgaat ctcggactgt tggcggcgga
    39001 acaaatcctt cctgtgctgc acaactgggc gcgcgccttg aagacggacg ggctgctgtt
    39061 ttttacctgc ttcgggcgcg acacttttac cgaactgaaa tgccgtctga aagaaaacgg
    39121 cattgaaagc cgcagcgtga tgtttcccga tatgcacgac ttgggcgata tgcttgctga
    39181 aaacggcttt tacgaccccg ttaccgatac ggcgaagctg gtgttggatt acaaaaaggc
    39241 ggaaacgttt tgggcggata tggacacgct gggcgtttgg cgggcgatgg cgtggaacga
    39301 tgaaaacgcc gcgcgttcgt gtgtcgggac aatatttgaa cgggaaggcg gtttgagtat
    39361 tacgctggaa acagtgtacg gacacgccgt taaaaaactg atgctgccgc aaggggagaa
    39421 cgtggtgcag ttttttccga agagatgatg tgcagatgcc gtctgaagcc gtttccaagt
    39481 ttcagacggc atttgtttgt gaaaaccgac agaactaaag gaaatgccga tgtatagtga
    39541 attaaattta aaccagtaca gcgttgcctc gccttgccgt actatttgta ctgtctgcgg
    39601 cttcgccgcc ttgtcctgat ttttgttaat ccactatatg ctgatgccgg agacgtatat
    39661 tgcgtctata acatcagact gaagcagtac actgcctgcc aggttacccg agttgaagaa
    39721 cacggtggca aaaaaacaca tgcgaccctg ctggctttgg actggcaggg caacaaaccg
    39781 cttggggcgg aggagctggc ggatttgaaa ccactttaca aagacttaaa gaataatatt
    39841 ggaaatattg tatgaacaaa aaattaaact atatttttat gttggactgt ttagggttgg
    39901 tgatattgtt tacttgtata atagctactt ttgaaagaga ttatggattt aaaattttta
    39961 ctaattctaa gaggcctgaa ttttattatt ggattggaat gttttattat g
//
LOCUS       DAXISH010000011        38133 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.011, whole genome shotgun sequence.
ACCESSION   DAXISH010000011 DAXISH010000000
VERSION     DAXISH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 38133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38133
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.011"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..1073
                     /locus_tag="ACFOV4_000592"
     CDS             <1..1073
                     /locus_tag="ACFOV4_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NnrS family protein"
                     /protein_id="HFC7618665.1"
                     /translation="RPFFVGAAVLAILGALVFFINPGAIVLHRQIFLELMLPAAYGGF
                     LTAALLDWTGFSGNLKPVATLMAALLLAASAILPFSPQTASFFVAAYWLVLLLFCARL
                     IWLDRNTDNFALLMLLAAFTVFQTAYAVSGDLNLLRAQVHLNMAAVMFVSVRVSILLG
                     AEALKECRLKDPVFIPNVVYKNIAITFLLLHAAAELWLPAQTAGFTSLAVGFILLAKL
                     RELHHHELLRKHYVRTYYLLQLFAAAGYLWTGAAKLQNLPASAPLHLITLGGMMGSVM
                     MVWLTAGLWHSGFTKLDYPKLCRIAVPILFAAAVSRTFLMNVNPIFFITIPAILTAVV
                     FTLYLFTFVPIFRANAFTGDPE"
     gene            complement(1119..3308)
                     /locus_tag="ACFOV4_000593"
     CDS             complement(1119..3308)
                     /locus_tag="ACFOV4_000593"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFC7618666.1"
                     /translation="MIYHRIAVNVPLSDGLLTYSHSDPLPPGTRVLVPFRNKTVVGMV
                     WETDIAPDMDTARILSVRTAFSDEPLLPESWRDLLSFTSRYYHYPTGQAVFAALPQGL
                     KETRAVEMPQPPLFYALNEAGRAQTPPPARFNKKAALWDALLSGEMTMAALKQVNAQA
                     AKLIEDWAEQGWIETTEAAKPVLRSCNGQASHSEFVLNADQQKASDAIQTALGRFQPF
                     LLYGITGSGKTEVYFDAMAKVLAQGRQVLFLLPEINLTPQLLKRVGNRFADVPTAVLH
                     SQMAAGRRTQDYLRAMLGQAKLVIGTRLAVFTPMDDVGLIVVDEEHDGSFKQDNELRY
                     HARDLAVWRAKQGGCPIILGSATPSLESWHKAQSGAYRLLQLTERAHTAAQLPQVDIL
                     NVGRLKLDNGFSPQALQLLKQNFEAGGMSLVYLNRRGFAPALFCGDCGHTFGCPNCSA
                     KMVLHQRARQLRCHHCDHREPIPYKCPDCGNQDLTAVGHGTQRVEETLRTFLPKAAVV
                     RVDRDSTAHKNDWADLYRRIADNKIDILVGTQMLAKGHDFARLNLVIVLNADGSLYSA
                     DFRAPERLFAELMQVSGRAGRADKPGKVLIQTQLPEHPVFAAVKAQDYAVFAENELNE
                     RQMFAMPPFGFQTAVRADAPRVADAMEFLNAAKETLAPLLPESVSQFGAAPMLMVRLA
                     ERERAQIFLESTSRQDLHRAVSLWVQVLQQNRDGKIRWSVDVDPQEA"
     gene            3447..4229
                     /locus_tag="ACFOV4_000594"
     CDS             3447..4229
                     /locus_tag="ACFOV4_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbC family protein"
                     /protein_id="HFC7618667.1"
                     /translation="MKTKLIKILTPFTVLPLLACGQTPVSNANAEPAVKAESAGKSVA
                     ASLKARLEKTYSAQDLKVLSVSETPVKGIYEVVVSGRQIIYTDAEGGYMFVGELINID
                     TRKNLTEERAADLNKIDFASLPLDKAIKEVRGNGKLKVAVFSDPDCPFCKRLEHEFEK
                     MTDVTVYSFMMPIAGLHPDAARKAQILWCQPDRAKAWTDWMRKGKFPVGGSICDNPVA
                     ETTSLGEQFGFNGTPTLVFPNGRSQSGYSPMPQLEEIIRKNQ"
     gene            complement(4547..6481)
                     /locus_tag="ACFOV4_000595"
     CDS             complement(4547..6481)
                     /locus_tag="ACFOV4_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MacB family efflux pump subunit"
                     /protein_id="HFC7618668.1"
                     /translation="MSLIECKNINRYFGSGENRVHILKDISLSIEKGDFVAIIGQSGS
                     GKSTLMNILGCLDTAGSGSYRIDDIETAKMQPDELAALRRERFGFIFQRYNLLSSLTA
                     RDNVALPAVYMGAGGKERSARAEKLLQDLGLASKEGNKPGELSGGQQQRVSIARALMN
                     GGEIIFADEPTGALDTASGKNVMEIIHKLHEAGHTVIMVTHDPGIAANANRVIEIRDG
                     EIISDTSKNPEIPASNVGRIREKASWSFYYDQFVEAFRMSVQAVLAHKMRSLLTMLGI
                     IIGIASVVSVVALGNGSQKKILEDISSIGTNTISIFPGRGFGDRRSGRIKTLTIDDAK
                     IIAKQSYVASATPMTSSGGTLTYRNTDLTASLYGVGEQYFDVRGLKLETGRLFDENDV
                     KEDAQVVVIDQNVKDKLFADSDPLGKTILFRKRPLTVIGVMKKDENAFGNSDVLMLWS
                     PYTTVMHQITGESHTNSITVKIKDNANTQVAEKGLTDLLKARHGTEDFFMNNSDSIRQ
                     IVESTTGTMKLLISSIALISLVVGGIGVMNIMLVSVTERTKEIGIRMAIGARRGNILQ
                     QFLIEAVLICVIGGLVGVGLSAAVSLVFNHFVTDFPMDISAASVIGAVACSTGIGIAF
                     GFMPANKAAKLNPIDALAQD"
     gene            complement(6547..7725)
                     /locus_tag="ACFOV4_000596"
     CDS             complement(6547..7725)
                     /locus_tag="ACFOV4_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MacA family efflux pump subunit"
                     /protein_id="HFC7618669.1"
                     /translation="MAKMMKWAAVAAVAAAAVWGGWSYLKPEPQASYITETVRRGDIS
                     QTVSATGEISPSNLVSVGAQASGQIKKLYVRLGQQVKKGDLIAEINSTTQTNTLNMEK
                     SKLETYQAKLVSAQIALGSAEKKYKRQAALWKDDATSKEDLESAQDALAAAKANVAEL
                     KALIRQSKISINTAESELGYTRITATMDGTVVAILVEEGQTVNAAQSTPTIVQLANLD
                     MMLNKMQIAEGDITKVKAGQDISFTILSEPDTPIKAKLDSVDPGLTTMSSGGYNSSTD
                     TASNAVYYYARSFVPNPDGKLATGMTTQNTVEIDGVKNVLIIPSLTVKNRGGKAFVRV
                     LGADGKAAEREIRTGMRDSMNTEVKSGLKEGDKVVISEITAAEQQESGERALGGPPRR
                     "
     gene            7951..8340
                     /locus_tag="ACFOV4_000597"
     CDS             7951..8340
                     /locus_tag="ACFOV4_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin protein"
                     /protein_id="HFC7618670.1"
                     /translation="MKNVQKGFTLLELMITVAILGILTLITYPSYKTYIRRVRLTEVR
                     TTLLHNAQTMERYYRQKGTFEHYNLTKLEQNEYFDITLSEVSPDHFTLKATPNPTTND
                     GETCVVTLNDGGTIAASGTNQSCPGFD"
     gene            8371..8493
                     /locus_tag="ACFOV4_000598"
     CDS             8371..8493
                     /locus_tag="ACFOV4_000598"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618671.1"
                     /translation="MPSGHSFRRHFYGFAVRFFKLETCRPSSGNRPDAAPFQLL"
     gene            8622..9668
                     /gene="adhP"
                     /locus_tag="ACFOV4_000599"
     CDS             8622..9668
                     /gene="adhP"
                     /locus_tag="ACFOV4_000599"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HFC7618672.1"
                     /translation="MKMQAVVVNKNVAGDVEIVEREVRPLKYGEALVEVEYCGVCHTD
                     LHVAAGDYGEKPGRVLGHEGIGLVKEVADGVKNLKVGDRVSIAWLFQSCGSCEYCNTG
                     RETLCRSVLNAGYTADGGMATYCIVSADYAVKVPEGLDPAQASSITCAGVTTYKAIKV
                     SSVRPGQWIAIYGAGGLGNLGVQYAKKVFGAHVVAIDINDDKLAFAKETGADLVVNAA
                     KEDAAKVIQEKTGGAHAAVVTAVSAAAFNSAVNCVRAGGRVVAIGLPPESMDLSIPRL
                     VLDGIEVVGSLVGTRKDLEEAFQFGAEGLVVPKVQLRALDEAPAIFQEMREGKITGRM
                     VIDMKKECGCGHHH"
     gene            complement(10019..13504)
                     /gene="smc"
                     /locus_tag="ACFOV4_000600"
     CDS             complement(10019..13504)
                     /gene="smc"
                     /locus_tag="ACFOV4_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFC7618673.1"
                     /translation="MRLTHIKLSGFKSFTDPTTIHVPGQLVAVIGPNGCGKSNVIDAV
                     RWVLGEASAKQLRGESMQDVIFNGAATRRPAPRASVELVFDNSDHSLQGAWGQYAEVS
                     IKRQLTRQGESTYFINNQTVRRRDITDLFLGTGVGARGYAVIEQGMISRIIEARPEEL
                     RAYIEEAAGVSKYKERRKETEGRLKDTREHLQRLGDLQNELARQVEKLEKQAETAERY
                     KSLTAQLNQQQDLLDYAQWQQSLAAADKATAQHQSLQAQQDETAAQVQALNDEVHALQ
                     TTEQSQQQAVHELGNKRGVLREQIARLEEQIRHQQNLHQRIERDKQAAQAQMQRIHQE
                     QQQIRVKLEENESQVEEKQTELAEWAMQVAEHEERLPELEETQTALNAAFQTQQDEAN
                     RIRRELALKQQQLAHAEQTVAKHEERKGRLKQENQALNLPDEAETAAAQEAAALLQSR
                     QEHYEEQIIAAEEALHAAREAFQTASNRFQSLKQQHITLQAQQQALSQILSQQQEAAD
                     FWQATGHAAAPQLWQHITAPAEWQHALSVILAERLHARDVPQGFVPPEPLPQGQAAWL
                     SDGLSGGIKKSLPVQALLNQIQAQPPFQTALHHWLDGVLCAPDLSYALAHQNDLGAHQ
                     IWLTPEGHQVDKVSVLLYAKPAQESLIAQKAHLDGIASELDNLAPELSAAEAAFKQAE
                     AAVRSSEVQHKNLMQQQQQHTRQYSQAQQRAAELLARTNQGQIRREHIERELAQLAEE
                     QTVLQHTSDGLSDDIAILQEAAAELEHQQQTAAHSRQEQQGRLKQAQLALLEANRQYG
                     LAEVAVHKLNQQKQNYQQQIAQLEQQTFDWQERQQELALAYETEFQNDEQHIKLEELS
                     EAVQSLDEEYIVVQEKLAQIQEQGREQYARVQTLQTKLPQLQAATQTALLQQQEALIN
                     AKRYHQNLTERAADLDALEALAKESPKVLNSSIGSLSQQIEALGAVNLAALQELEEAR
                     ERDGYYRSQSEDVQTAITLLEEAIAQIDDKTKARFKETFDAVNGKVQTFFPTLFGGGE
                     ATLKMIGDDLLTAGVSIMARPPGKKNSTIHLLSGGEKALTAMSLVFALFSLNPAPFCL
                     LDEVDAPLDDANTSRFCNLVKEMSAQTQFLYISHNRLTMEMAEQLVGVTMQEKGVSRV
                     VAVDIKQALEMAESV"
     gene            13488..13757
                     /locus_tag="ACFOV4_000601"
     CDS             13488..13757
                     /locus_tag="ACFOV4_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009345706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618674.1"
                     /translation="MWVRRIMVGKNKKEAYFNGNPAAPPHILPAKPYRIPHPRCRLKP
                     SDGIFNAPEPRFRQRPMLGAAFAVLPRRRARYNPPRHPPDLETCL"
     gene            13754..14476
                     /gene="lpxH"
                     /locus_tag="ACFOV4_000602"
     CDS             13754..14476
                     /gene="lpxH"
                     /locus_tag="ACFOV4_000602"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HFC7618675.1"
                     /translation="MKPAYFISDLHLSEKHPELTALLLRFLRSSAAGQARAVYILGDL
                     FDFWVGDDEVSELNTSVAREIRKLSDKGVAVFFVRGNRDFLIGQDFCRQAGMTLLPDY
                     SVLDLFGCKTLICHGDTLCTDDRAYQRFRKIVHRKRLQKLFLMLPLKWRTRLAAKIRR
                     VSKMEKQVKPADIMDVNAAFTARQVRAFNAERLIHGHTHREHIHHENGFTRIVLGDWH
                     NDYASILRVDGDGAVFVPLEKC"
     gene            14745..16331
                     /locus_tag="ACFOV4_000603"
     CDS             14745..16331
                     /locus_tag="ACFOV4_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HFC7618676.1"
                     /translation="MALFLSIFPIVLLIWLMVKKNSMPSYVALPITAVLIYAIKLFYF
                     GDAGMLLNATAASGLVKTLTPITVIFGAIMFNRMMETTGCIDVIRKWLATISPNPVAQ
                     LMIIGWAFAFMIEGASGFGTPAAIAAPILMSLGFNPLKVAIFTLVMNSVPVSFGAVGT
                     PTWFGFAPLNLSAEDILAIGRQTGVMHFFAGFVIPVIGLGFIVPWSEIRKNLGFVAIA
                     VFSCTIPYVALAMVNEEFPSLVAGAIGLMVSVFAANQGWGLSKDHAKDPNAEKVPFAQ
                     VAKALAPLGMLIGMLVVTRIKQLGIKGILTSKEEWFSFQLPFDLSKITVSDSLTITFG
                     NIFGQDVSASYQTLYVPAWIPFVLTVWICILLYKTKFKDAWTIYAVTFNQTKKPLLAL
                     MGALIMVQLMLVGGDNSMVKIIGKEFAAMAGEHWVYFSPYLGAIGAFFSGSNTVSNLT
                     FGPIQQQIALDTGLSVTLILALQSVGGAMGNMVCLNNIIAVCTVLDVKNSEGAIIKKT
                     VIPMAIYGVIAVVAAMIFFL"
     gene            complement(16500..16703)
                     /locus_tag="ACFOV4_000604"
     CDS             complement(16500..16703)
                     /locus_tag="ACFOV4_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-finger domain-containing protein"
                     /protein_id="HFC7618677.1"
                     /translation="MDNLNLQEISVLPENLPLYCSGPDNEQWNGHPRVFLPLCEGESG
                     SVACPYCGTRYRLDGKMPHHHYA"
     gene            16819..17316
                     /locus_tag="ACFOV4_000605"
     CDS             16819..17316
                     /locus_tag="ACFOV4_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-mimic protein DMP19"
                     /protein_id="HFC7618678.1"
                     /translation="MTALTLPEDIRQQEPSVLLYTLVSAYLEHTAQTGDESLSCLSDD
                     QHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKAL
                     YEQHGETIETLADGGADIESLRKQFPDFEEWDGAYYEAAEQDLPLLAEHILSNWETFA
                     HIGQA"
     gene            17398..18591
                     /locus_tag="ACFOV4_000606"
     CDS             17398..18591
                     /locus_tag="ACFOV4_000606"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid aminotransferase"
                     /protein_id="HFC7618679.1"
                     /translation="MFFKHIEAALADPILGLGEAFKAETRPEKVNLGIGVYKDASGAT
                     PIVKAVKEAEKHLLESETTKNYLTIDGVADYNAQTQILLFGKDHEIIASRRAKTAQSL
                     GGTGALRIAAEFAKRQLNAQTIWISNPTWPNHNAIAKAVGIQDKPYRYYDAAKHGLDW
                     DGMIEDLSRAQKGDIVLLHGCCHNPTGIDPTPEQWETLAKLSAEKGWLPLFDFAYQGF
                     GNGLEEDAYGLRVFLKHNTELLIASSYSKNFGMYNERVGAFTLVAEDEETAIRAHSQV
                     KTIIRTLYSNPASHGANTIALVLKNDDLKAQWIAELDEMRGRIKAMRQKFVALLKAKG
                     ASQDFDFIIEQNGMFSFSGLTPEQVDRLKNEFAIYAVRSGRINVAGITDDNIDYLCES
                     IVKVL"
     gene            complement(18995..19930)
                     /gene="hemC"
                     /locus_tag="ACFOV4_000607"
     CDS             complement(18995..19930)
                     /gene="hemC"
                     /locus_tag="ACFOV4_000607"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HFC7618680.1"
                     /translation="MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTR
                     GDQILDKTLSKVGGKGLFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERA
                     NPFDAFVSNQYARLEEMPKGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLD
                     NGEYDAIILAAAGLQRLELDERIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKP
                     LNHDTTHACVTAERALARALGGSCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADA
                     QAPAEYADALGRAVAKKLADDGARELIGAVLNTEN"
     gene            20049..20564
                     /gene="ybeY"
                     /locus_tag="ACFOV4_000608"
     CDS             20049..20564
                     /gene="ybeY"
                     /locus_tag="ACFOV4_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFC7618681.1"
                     /translation="MKRTKKYPFLTLQRQRFHLNFENASSAAGIPAERDFYRWAWSAL
                     KSGYRRADISLILLDEEEARAYNRDYRGKDYATNVLSFALNEGEILPCQVSEKLYGDL
                     IICPQVVLKEAAEQGKTPERHFAHLTIHGVLHLMGYDHIEDDEAEIMEAEEIRLMLAA
                     GFPNPYQEDEY"
     gene            20566..21390
                     /locus_tag="ACFOV4_000609"
     CDS             20566..21390
                     /locus_tag="ACFOV4_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HFC7618682.1"
                     /translation="MDGTQSKPKFFERLISRLAGEPDSAEDVLTLLRQAHEQEVFDAD
                     TLLRLEKVLDFSDLEVRDAMITRSRMNVLKENDSIERITAYVIDTAHSRFPVIGEDKD
                     EVLGILHAKDLLKYMFNPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVID
                     EYGGTSGLVTFEDIIEQIVGDIEDEFDEDESADNIHAVSSERWRIHAATEIEDINTFF
                     GTEYSSEEADTIGGLVIQELGHLPVRGEKVIIGSLQFTVARADNRRLHTLMATRVK"
     gene            complement(21533..22912)
                     /gene="nhaC"
                     /locus_tag="ACFOV4_000610"
     CDS             complement(21533..22912)
                     /gene="nhaC"
                     /locus_tag="ACFOV4_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFC7618683.1"
                     /translation="MFAFKSLLDMPRGEALAVVVALIAAMGYTIISLEWLPHMSIIAA
                     IVVLILYGLARGLKYNDMQQGMIGALNQGMGAIYLFFFIGLMVSALMMSGAIPTLMYY
                     GFGLISPTYFYFSAFALCSVIGVSIGSSLTTCATVGVAFMGMAAAFQADMAMTAGAIV
                     SGAFFGDKMSPLSDTTGISASIVGIDLFEHIKNMMYTTIPAWLISAALMLWLLPSVAA
                     QDLNSVESFRSQLEATGLVHCYSLIPFALLVVLALMRVNAVVAMLFTVIAAVAVTYLH
                     STPDLRQLGAWFYGGYKLEGEAFKDIAKLISRGGLESMFFTQTIVILGMSLGGLLFAL
                     GAIPSLLDAVRSFLTNAGRATFSVAMTSVGVNFLIGEQYLSILLSGETFKPVYDKLGL
                     HSRNLSRTLEDAGTVINPLVPWSVCGVFISHALGVPVWEYLPYAFFCYLSLALTLLFG
                     WTGLTLSKK"
     gene            complement(23203..24426)
                     /locus_tag="ACFOV4_000611"
     CDS             complement(23203..24426)
                     /locus_tag="ACFOV4_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar MFS transporter"
                     /protein_id="HFC7618684.1"
                     /translation="MSAQSQNNHTSPLVVLTTLFFMMGFITCMNDILIPHLKEIFDLS
                     YVQAMLIQFCFFTAYAVMSIPMGAFVGKVGYKNGVIGGFLLTAVGCLLFYPAAGSHSY
                     AVFLGALFILASGVTLLQVAGNPYVTLLAKPGKESATLTLVQAFNALGTTIAPQIGAF
                     LILADATQTVSKAEQISSVQIPYLGLAGLLIILAVFVKMIRLPDARKIAAEESAHNHD
                     GKTSVWQYKHLVFGTAGIFCYVGAEVSIGSLMVNVLGYLKGLDHASAAHYLSFYWGGA
                     MVGRFLGSAVMAKFAPNRYLAFNASAAVVLLAVAMATGSGNADVAMWSLLAIGFFNSI
                     MFPTIFSLATKGLGKFTNAASGVLCTAIVGGAVVPVVQGWVADTYTLMSSFVVSVICY
                     LYIVFFAVYGYRADK"
     gene            25016..25429
                     /locus_tag="ACFOV4_000612"
     CDS             25016..25429
                     /locus_tag="ACFOV4_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqaA family protein"
                     /protein_id="HFC7618685.1"
                     /translation="MMPAYAYAALAFSAFTSATLLPGTSEAAFALFVHRFPEHAYGAL
                     LCAGLANGLGSMVSYWMGRLLPSRKMPSEKTLNLMRRFGIWLLAFAWLPVVGDALPLA
                     AGWLRLNPWTSGLMLVIGKTARYAFILWGMQYYAA"
     gene            25475..26104
                     /gene="nth"
                     /locus_tag="ACFOV4_000613"
     CDS             25475..26104
                     /gene="nth"
                     /locus_tag="ACFOV4_000613"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFC7618686.1"
                     /translation="MNRHIRQEIFERFRAANPHPTTELNFNSPFELLIAVLLSAQATD
                     VGVNKATAKLFPVADTPQAMLDLGLDGVMEYTKTIGLYKTKSKHIMQTCRILLEKYNG
                     EVPEDREALESLPGVGRKTANVVLNTAFGHPVMAVDTHIFRVSNRTKIAPGKDVREVE
                     DKLMRFIPKEFLMDAHHWLILHGRYTCKALKPQCQTCIINDLCEYPAKA"
     gene            26242..27741
                     /locus_tag="ACFOV4_000614"
     CDS             26242..27741
                     /locus_tag="ACFOV4_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegQ family serine endoprotease"
                     /protein_id="HFC7618687.1"
                     /translation="MFKKYQYLALAALCAASLAGCDKAGSFFGADKKEASFVERIKHT
                     KDDGSVSMLLPDFVQLVQSEGPAVVNIQAAPAPRTQNGSSNAENDSDPLADSDPFYEF
                     FKRLVPNMPEIPQEEADDGGLNFGSGFIISKDGYILTNTHVVTGMGSIKVLLNDKREY
                     TAKLIGSDVQSDVALLKIDATEELPVVKIGNPKDLKPGEWVAAIGAPFGFDNSVTAGI
                     VSAKGRSLPNESYTPFIQTDVAINPGNSGGPLFNLKGQVVGINSQIYSRSGGFMGISF
                     AIPIDVAMNVAEQLKNTGKVQRGQLGVIIQEVSYGLAQSFGLDKAGGALIAKILPGSP
                     AERAGLRAGDIVLSLDGGEIRSSGDLPVMVGAITPGKEVSLGVWRKGEEITIKVKLGN
                     AAEHIGASSKTDEAPYTEQQSGTFSVESAGITLQTHTDSSGGHLVVVRVSDAAERAGL
                     RRGDEILAVGQVPVNDEAGFRKAMDKAGKNVPLLVMRRGNTLFIALNLQ"
     gene            27943..29463
                     /locus_tag="ACFOV4_000615"
     CDS             27943..29463
                     /locus_tag="ACFOV4_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HFC7618688.1"
                     /translation="MQLIDYSHSFFSVVPPFLALALAVITRRVLLSLGIGILVGVAFL
                     VGGNPVDGLTHLKDMVVGLAWSDGDWSLGKPKILVFLILLGIFTSLLTYSGSNQAFAD
                     WAKRHIKNRRGAKMLTACLVFVTFIDDYFHSLAVGAIARPVTDKFKVSRAKLAYILDS
                     TAAPMCVLMPVSSWGASIIATLAGLLVTYKITEYTPMGTFVAMSLMNYYALFALIMVF
                     VVAWFSFDIGSMARFEQAALNEAHDETTVSDATKGRVYALIIPVLALIASTVSAMIYT
                     GAQASETFSILGAFENTDVNTSLVFGGTCGVLAVVLCTLGTIKTADYPKAVWQGAKSM
                     FGAIAILILAWLISTVVGEMHTGDYLSTLVAGNIHPGFLPVILFLLASVMAFATGTSW
                     GTFGIMLPIAAAMAVKVEPALIIPCMSAVMAGAVCGDHCSPISDTTILSSTGARCNHI
                     DHVTSQLPYALTVAAAAASGYLALGLTKSALLGFGTTGIVLAVLIFLLKDKKRANA"
     gene            29520..30605
                     /gene="nagZ"
                     /locus_tag="ACFOV4_000616"
     CDS             29520..30605
                     /gene="nagZ"
                     /locus_tag="ACFOV4_000616"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HFC7618689.1"
                     /translation="MTVPHIPRGPVMADIAAFRLTGEEKQRLLDPAVGGIILFRRNFQ
                     NIEQLKTLTAEIKALRTPELIIAVDHEGGRVQRFIEGFTRLPAMSTLGEIWDKDGASA
                     AETAAGQVGRVLATELSACGIDLSFTPVLDLDWGNCPVIGNRSFHSNPEAVTRLALAL
                     QKGLAKGGMKSCGKHFPGHGFVEGDSHLVLPEDGRSLDELEAADLIPFRIMSREGMAA
                     VMPAHVVYPQVDTKPAGFSEIWLKQILRRDIGFKGVIFSDDLTMEGACGAGGIKERAR
                     ISFEAGCDIVLVCNRPDLVDELRDDFRIPDNPALAQRWQYMANTLGSAAAQAVMQTAD
                     FQAAQAFVAALASPQDTAGGVKVGEAF"
     gene            30686..30762
                     /locus_tag="ACFOV4_000617"
     tRNA            30686..30762
                     /locus_tag="ACFOV4_000617"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30720..30722,aa:Pro,seq:cgg)
     gene            complement(31097..31735)
                     /locus_tag="ACFOV4_000618"
     CDS             complement(31097..31735)
                     /locus_tag="ACFOV4_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003777273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HFC7618690.1"
                     /translation="MKKINVAPENPQYRIVEIFESLQGEGWNTGMPAVFVRLGKCNLA
                     CGWCDTDYLTFGMMSLSDILGCLKTYAARNIIITGGEPTIQPHLDMLLDTLKAEGYFL
                     CLETNGLNPAPPQIDYVATSPKACYAAKYENSCIETADEVRIVADGDVLAFCENMERK
                     IRAHHYYLSPCEQDGAMNIYDTIRQIGILNSRPDASVHWQLSVQTHKWAGIE"
     gene            complement(31732..32103)
                     /locus_tag="ACFOV4_000619"
     CDS             complement(31732..32103)
                     /locus_tag="ACFOV4_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFC7618691.1"
                     /translation="MKLLFILLVLFVAVEHFYIAWLEMTQIPSEKAAETFKLPYEFME
                     QNRVQTLFGNQGLYNGFLGIGLVWSRFAAPDNAVYGVTVLFLGFVLIAAAWGAFSSGN
                     KGILVKQGLPAFLAAAAVLAV"
     gene            complement(32208..32333)
                     /locus_tag="ACFOV4_000620"
     CDS             complement(32208..32333)
                     /locus_tag="ACFOV4_000620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618692.1"
                     /translation="MKSMDIRFARIAALTKQLAAIQRQIEKRAYKAKAATMKKVA"
     gene            complement(32353..32709)
                     /locus_tag="ACFOV4_000621"
     CDS             complement(32353..32709)
                     /locus_tag="ACFOV4_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618693.1"
                     /translation="MNTTSSMIQEEGIIAESIDVINKFVQFLLKLYDDFGIDGMHDLV
                     DPDLDTLESIVKNLQQEVDKLPISPNDFSLENKKISLAQGLLYAQSMITNVRNKDTEE
                     CSRNRSMLKNNQSSLY"
     gene            complement(32818..33240)
                     /gene="queD"
                     /locus_tag="ACFOV4_000622"
     CDS             complement(32818..33240)
                     /gene="queD"
                     /locus_tag="ACFOV4_000622"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HFC7618694.1"
                     /translation="MKITKIFTFDSSHMLDGHDGKCQNLHGHTYKLEITVSDGIIKGG
                     AKDGMVMDFTDLKAIVKQHITDPFDHAFIYHGGNSRECQIAALLEGWNMKTLRLPCRT
                     TAENMAVEMYDRLKNAGLNVCRVKLWETPTSCAEYEGE"
     gene            complement(33247..33765)
                     /locus_tag="ACFOV4_000623"
     CDS             complement(33247..33765)
                     /locus_tag="ACFOV4_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003698058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1543 domain-containing protein"
                     /protein_id="HFC7618695.1"
                     /translation="MPKLHMFYLGGNAGRSNIEVHDIQFAVCDDYREAVPALKAAWFG
                     DADKIHIDGWQIVEWADGYDIAVSETPKTKMPSEHAPRLYFANVGGYRAGQLAEAHAF
                     GLFAAATPAEAKQKALQTLLTDSYVQQHKDNLKDVDNLLALDRIGNFHIRLTPNPHGK
                     PAEIGFQGYLPI"
     gene            complement(33793..34452)
                     /gene="queC"
                     /locus_tag="ACFOV4_000624"
     CDS             complement(33793..34452)
                     /gene="queC"
                     /locus_tag="ACFOV4_000624"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HFC7618696.1"
                     /translation="MSNQKALVIFSGGQDSTTCLIQAIQIYGRENVQAITFQYGQRHA
                     VELERASWIAQDLGVKQTVLDLSLMRQITHNALMDDTAAIETAENGVPNTFVDGRNAL
                     FLLYAAIYAKGQGIRHIIAGVCETDFSGYPDCRDVFVKSMNVTLNLAMDYDFQIHTPL
                     MYLTKAQTWALADEMGVLDYIREQTHTCYNGIVGGCRECPSCILRERGLAEYLESKKA
                     V"
     gene            complement(34656..34842)
                     /locus_tag="ACFOV4_000625"
                     /pseudo
     CDS             complement(34656..34842)
                     /locus_tag="ACFOV4_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003779592.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            34997..36223
                     /locus_tag="ACFOV4_000626"
     CDS             34997..36223
                     /locus_tag="ACFOV4_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003699499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY family inner membrane protein"
                     /protein_id="HFC7618697.1"
                     /translation="MTFLQRLQGLADNKICAFAWFVVRRFDEERVPQAAASMTFTTLL
                     ALVPVLTVMVAVASIFPVFDRWSDSFVSFVNQTIVPQGADMVFDYINAFREQANRLTA
                     IGSVMLVVTSLMLIRTIDNTFNRIWRVNSQRPWMMQFLVYWALLTFGPLSLGVGISFM
                     VGSVQDAALASGAPQWSGALRTAATLTFMTLLLWGLYRFVPNRFVPARQAFVGALATA
                     FCLETARSLFTWYMGNFDGYRSIYGAFAAVPFFLLWLNLLWTLVLGGAVLTSSLSYWQ
                     GEAFRRGFDSRGRFDDVLKILLLLDAAQKEGKALPVQEFRRHINMGYDELGELLEKLA
                     RYGYIYSGRQGWVLKTGADSIELNELFKLFVYRPLPVERDHVNQAVDAVMMPCLQTLN
                     MTLAEFDAQAKKQQQS"
     gene            complement(36244..36525)
                     /locus_tag="ACFOV4_000627"
     CDS             complement(36244..36525)
                     /locus_tag="ACFOV4_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFC7618698.1"
                     /translation="MIHEEISAMPMGYETLIGDMGSALSGGQKQRIVLARALYCEPKI
                     LFLDAATSHLDIANEKAVNANLNGLSIIKIMAAHRKETVESADRKMSLG"
     gene            complement(36604..36738)
                     /locus_tag="ACFOV4_000628"
                     /pseudo
     CDS             complement(36604..36738)
                     /locus_tag="ACFOV4_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225556.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            complement(36737..37195)
                     /locus_tag="ACFOV4_000629"
     CDS             complement(36737..37195)
                     /locus_tag="ACFOV4_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618699.1"
                     /translation="MLTKLKILLFLFLFVFVLAINLLFFFFSSDIESFGNYQFEYVYD
                     KGWPANYILVMKDGNEGNFDKIISGLVLEYYKEDDNIYFSYIDGQGFASDSCYYKPEI
                     LYGKIILNKNHIININSMEKNNFLSEDKIMKGTRNWLADPKNKCNIQTLD"
     gene            complement(37759..37962)
                     /locus_tag="ACFOV4_000630"
     CDS             complement(37759..37962)
                     /locus_tag="ACFOV4_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618700.1"
                     /translation="MLSLEIQQEGFTIGGGLVLGGCAGAHLARKEPLILTGKTGAGAS
                     AIANASIGYQWTVNLSEPKEGAK"
BASE COUNT         8838 a        10603 c         9671 g         9021 t
ORIGIN      
        1 tgcggccgtt tttcgtcggc gcggcggtgc ttgccatact cggtgcgctg gtgtttttca
       61 tcaaccccgg tgccatcgtc ctgcaccgcc aaattttctt ggaacttatg ctgccggcgg
      121 catacggcgg ttttttgact gcggctttgt tggactggac gggtttttcg ggtaacctga
      181 aacctgtcgc gactttgatg gcggcattat tgctcgccgc atccgctata ctgccctttt
      241 cgccgcaaac tgcctcgttt ttcgtcgccg cctattggct ggtgttgctg ctgttctgcg
      301 cccggctgat ttggctagac cgaaacaccg acaacttcgc cctgctaatg ttacttgccg
      361 cgttcactgt ttttcagacg gcatatgccg tcagcggcga tttgaacctg ttgcgcgcgc
      421 aagtgcatct aaatatggcg gcggtgatgt tcgtatccgt gcgcgtcagt attcttttgg
      481 gcgcggaagc cctgaaagaa tgccgtctga aagacccagt attcatcccc aatgtcgtct
      541 ataaaaacat cgccattacc ttcctgctcc tgcacgccgc cgccgaactt tggctgcctg
      601 cgcaaaccgc cggttttacc tcgctcgccg tcggctttat cctgcttgcc aagctgcgtg
      661 agcttcacca tcacgaactc ctgcgcaaac actacgtccg cacttattac ctgctccaac
      721 tctttgccgc cgcaggctat ttgtggacag gcgcggcgaa attacaaaac ctgcccgcct
      781 ccgcgcccct gcacctgatt accctcggtg gcatgatggg cagcgtgatg atggtgtggc
      841 tgaccgccgg actgtggcac agcggcttta ccaaactcga ctaccccaaa ctctgccgca
      901 ttgccgtccc catcctcttc gccgccgccg tctcgcgcac tttcttgatg aacgtgaacc
      961 cgatattctt catcaccatc cccgcgattc tgaccgccgt cgtgttcacg ctttatcttt
     1021 tcacgtttgt tccgattttt cgggcgaatg cgtttacggg cgacccggaa taaaaatgcc
     1081 gtctgaaacg gtttcagacg gcatcgtatt gccgataatc aagcctcctg cggatcgaca
     1141 tccaccgacc atctgatttt gccgtcgcgg ttttgctgca acacctgcac ccacaaactc
     1201 acggcacggt gcaaatcctg tcgggatgtc gattcgagga agatttgcgc gcgttcgcgt
     1261 tcggcgaggc gcaccatcag catcggggcc gcgccgaact gggaaacgct ttcgggcaac
     1321 agcggggcga gggtttcttt ggcggcattg agaaattcca tcgcatcggc aacgcgcggc
     1381 gcatcggcgc ggacggcggt ctggaaaccg aagggcggca tggcgaacat ttgccgctcg
     1441 ttcaattcgt tttcggcaaa cacggcatag tcttgcgctt tgacggcggc gaagacagga
     1501 tgttcgggca gttgggtctg tatcaacacc ttgccgggtt tgtcggcgcg ccccgccctg
     1561 cctgacactt gcatcagctc ggcaaacagc ctttccggcg cgcgaaagtc cgcgctgtac
     1621 aggctgccgt cggcgttcaa tacgataacg aggttgagcc gcgcgaaatc atggcctttg
     1681 gcaagcatct gcgtgccgac caaaatgtcg attttgttgt cggcgatgcg gcggtacaaa
     1741 tccgcccagt catttttgtg cgcggtgctg tccctgtcaa cacggacgac ggctgccttg
     1801 ggcaggaagg tgcgcagggt ttcttcgacg cgctgcgtgc cgtggccgac ggcggtcagg
     1861 tcttggttgc cgcagtcggg gcatttgtac gggatgggtt cgcggtggtc gcagtggtga
     1921 cagcgcagtt ggcgggcgcg ttggtgcagt accattttgg cggagcagtt tgggcagccg
     1981 aaggtatggc cgcagtcgcc gcaaaacagc gcgggtgcga agccgcgccg gttgaggtac
     2041 accagcgaca taccgcccgc ttcaaaattc tgtttcaaaa gctgcaaggc ttgcggcgag
     2101 aaaccgttgt cgagtttcag acggcctacg ttgagaatgt ccacttgcgg cagttgcgcg
     2161 gcggtatggg cgcgttcggt cagttgcagc aggcggtacg cgccgctttg cgccttgtgc
     2221 cagctttcca agctgggcgt ggcactgccc aatatgatgg ggcagccgcc ctgcttcgcc
     2281 cgccacaccg ccaaatcgcg ggcgtggtag cgcaattcgt tgtcttgttt gaacgagccg
     2341 tcgtgttcct catcgactac aatcagcccg acatcatcca tcggcgtaaa caccgccagc
     2401 cgcgtgccga tgaccaattt cgcctgcccc aacatcgcgc gcaaataatc ctgcgtgcgc
     2461 ctgcctgccg ccatctgact gtgcaacacg gcggtcggca cgtcggcaaa acgatttccc
     2521 acccgcttca aaagctgcgg cgtgaggttg atttcgggca acagaaacaa cacctgccgc
     2581 ccctgagcca acactttcgc catcgcatcg aaatacactt cggtcttgcc gctgccggtg
     2641 atgccgtaca gcagaaacgg ctggaagcgt cccaatgccg tctgaatggc atcggaagcc
     2701 ttctgctggt cagcatttaa tacaaattca gagtgcgaag cctgcccatt acacgacctt
     2761 aaaacgggct tcgccgcttc cgtcgtttca atccaaccct gctccgccca atcttcgatt
     2821 aacttcgccg cctgcgcgtt tacctgcttc aacgctgcca tcgtcatttc gcccgacagc
     2881 agcgcgtccc acaaagccgc ttttttgttg aaccgcgccg gcggcggcgt ttgcgccctg
     2941 cccgcttcgt tcaacgcgta aaacaagggc ggctgcggca tttccaccgc gcgcgtttcc
     3001 ttcaaacctt gcggcaatgc ggcaaatact gcctgcccgg tcggatagtg gtaataacgc
     3061 gacgtaaacg agagcaaatc acgccagctt tcgggcagca gcggctcgtc cgaaaaggcc
     3121 gtccgaacgc tcaaaatccg cgccgtatcc atatccggcg caatatccgt ttcccacacc
     3181 atcccgacca cggttttatt gcggaaaggc acaagcaccc gcgttcccgg aggaagcgga
     3241 tcggaatggg aataagtcaa aaggccgtct gaaagcggca cgtttacggc gatgcggtgg
     3301 tagatcatac aggcaggcaa atcatttttt tgcgtatttt aacaggcgga agctattttc
     3361 agacgataaa ttgagcctag gcgcaatgca ggcgcaacag agatttgata caattccgct
     3421 tttccaacac gcgcaatcat ctttatatga aaaccaagtt aatcaaaatc ttgaccccct
     3481 ttaccgtcct cccactgctg gcttgcgggc aaacgcccgt ttccaatgcc aacgccgaac
     3541 ccgccgtcaa agccgagtcc gccggcaaat ccgttgccgc ctctttgaaa gcgcgtttgg
     3601 aaaaaaccta ttccgcccaa gatttgaaag tgttgagcgt cagcgaaaca ccggtcaaag
     3661 gcatttacga agtcgtcgtc agcggcaggc agattatcta caccgatgcc gaaggcggct
     3721 atatgttcgt cggcgaactc atcaacatcg acacgcgcaa aaacctgacc gaagaacgcg
     3781 ccgccgattt gaacaaaatc gacttcgcct ccctgccttt ggacaaagcc atcaaagaag
     3841 tgcgcggcaa cggcaagctg aaagtcgccg tcttttccga ccccgattgt ccgttctgca
     3901 aacgcttgga acacgagttt gaaaaaatga ccgacgtgac ggtttacagc tttatgatgc
     3961 ccattgccgg cctgcacccc gatgccgcgc gcaaggcgca aatcttatgg tgtcagcccg
     4021 accgcgccaa agcgtggacg gattggatgc gtaaaggcaa attcccggtc ggcggcagca
     4081 tctgcgacaa tcccgtcgcg gaaaccactt ccttgggcga acaattcggc ttcaacggca
     4141 cgccgaccct cgtcttcccc aacgggcgca gccaaagcgg ctacagcccg atgccccaac
     4201 tggaggaaat catccgcaaa aatcaataat ccatccgcaa aacaaaaggc ttggaaaatt
     4261 ccaagccttt tttgcgggaa atgccgcctg aaaaccaatc cgcactgaaa gttatagtgg
     4321 attaaattta tagtggatta aatttaaacc agtacagcaa gccaacaaac acatcctaac
     4381 ccattgaatg attgaaaata ataaattgaa caatacgaaa cacaccgccg tcattcccac
     4441 gcaagtggga atttggaacg tagaatctaa gaaaccgttt ttgtccaata agtttctgct
     4501 ccaaaatgac cggttctgca gcttcaggcg gcatctttgt ccaacctcaa tcctgtgcca
     4561 atgcgtctat cggattgagt ttggctgctt tattggcagg cataaagccg aacgcgatgc
     4621 cgattccggt cgagcaggcg accgccccga taacggatgc cgccgaaatg tccatcggga
     4681 agtcggttac aaaatgattg aacacgaggc tgacggcggc ggacaaaccc acgccgacca
     4741 aaccgccgat gacgcagatt aacaccgcct caatcaaaaa ctgctgcaaa atattgccgc
     4801 gccgcgcgcc gattgccatc cgtatgccga tttctttggt gcgctcggta acggacacca
     4861 gcatgatgtt catcacgccg atgccgccga ctaccaatga aatcagggcg atggaggaaa
     4921 tcagcagctt catcgtaccg gtggtgcttt cgactatctg cctgatgctg tcgctgttgt
     4981 tcatgaagaa atcttccgtg ccgtgccgcg ctttgagcag atcggtcagc cctttttcgg
     5041 caacctgggt attggcattg tctttgattt tgacggtgat ggagttggtg tggctctcgc
     5101 ctgtgatttg gtgcatcacc gtcgtatagg gcgaccaaag catcagcacg tcggaattgc
     5161 cgaaagcgtt ttcgtctttt ttcatcacgc cgatgacggt caaggggcgt ttcctgaaca
     5221 aaatggtttt acccaacgga tccgagtccg caaagagttt gtctttgaca ttttggtcga
     5281 tgacgacgac ctgcgcgtct tctttcacat cgttttcgtc aaacagccgc cccgtttcca
     5341 gcttcagtcc gcgcacgtcg aaatattgtt cgcccacgcc gtacaaagaa gcggtcaggt
     5401 cggtattgcg gtaagtcagc gtgccgccgc tcgaagtcat gggcgtggcg gaagcaacgt
     5461 agctttgttt ggcgatgatt tttgcgtcgt ctatggtcag ggttttaatc ctgccgctgc
     5521 gcctgtcgcc gaagccgcgc cccgggaaga tgctgatggt gttcgtccct atcgaactga
     5581 tgtcttcaag gatttttttc tgcgaaccgt tgcccaatgc gacgacggaa accaccgacg
     5641 cgatgccgat gatgatgccg agcatcgtca gaagcgaacg cattttgtgc gccaatactg
     5701 cttgcaccga cattctgaag gcttcgacaa actggtcgta ataaaacgac cacgaggctt
     5761 tttcccgaat cctcccgaca ttgcttgcgg ggatttcggg atttttcgag gtgtcggaaa
     5821 tgatttcgcc gtcccggatt tcgatgacgc ggttggcatt ggcggcgatg ccggggtcgt
     5881 gcgtgaccat aatgacagta tgcccggctt cgtgcagctt gtggatgatt tccatcacgt
     5941 ttttgccgct ggcggtatcg agtgcgccgg tcggctcgtc ggcgaagatg atttctccgc
     6001 cgttcatcag ggcgcgggcg atggagacgc gctgctgctg tccgcccgag agttcgccgg
     6061 gcttgttgcc ctctttgctt gccaaaccca aatcctgcaa caacttctcc gcacgcgcgg
     6121 aacgctcttt gccgcccgcg cccatataga cggctggcag cgcgacgttg tcccttgcgg
     6181 tcagcgagct taagaggttg tagcgttgga agatgaaacc gaagcgttcg cggcgcaatg
     6241 ccgccagctc gtcaggctgc attttggcag tttcgatgtc gtcgattcgg tacgaaccgg
     6301 aaccggcggt atccaaacag ccgagtatgt tcatcagcgt ggacttgccc gaaccggact
     6361 gcccgatgat ggcgacaaaa tcgcccttct ctatcgacag gctgatgtct ttcaaaatat
     6421 ggacgcggtt ctcgccgctg ccgaaatagc ggttgatgtt tttacattcg atcaagctca
     6481 taatattccg taaatcaata acaaatgccg tctgaaaccg tttccgtgtt cagacggcat
     6541 attcgtttat cggcgcggcg ggccgcctag ggcgcgttcg ccgctttcct gctgctcggc
     6601 ggcggttatt tcggagatga ccactttgtc cccctctttc aacccgcttt ttacttcggt
     6661 attcatactg tctctcatac cggtccggat ttcgcgttcc gccgccttgc cgtccgcacc
     6721 caacacgcgc acaaacgcct tgccgccgcg atttttcacg gtcagcgacg gaataatcag
     6781 cacatttttc acgccgtcga tttcaaccgt attctgcgtc gtcatccccg tggcgagttt
     6841 gccgtccgga ttcggcacaa acgaacgggc ataatagtag accgcattgg aagccgtatc
     6901 cgtactgctg ttgtaaccgc ccgacgacat cgtggtcagc ccggggtcga cgctgtcgag
     6961 cttcgcctta atcggcgtat ccggttcgga caaaatcgta aacgaaatat cctgccccgc
     7021 cttcaccttg gtaatatcgc cctcggcaat ctgcattttg ttcaacatca tatccagatt
     7081 cgccaattgg acaatcgtcg gcgtagactg cgccgcgttc acagtctgcc cctcttccac
     7141 gagaatcgcc accaccgtgc cgtccatcgt tgcggtaatg cgcgtgtagc ccaattccga
     7201 ctcggcggta ttgatggaaa ttttgctctg tctgattaga gccttcagct cggcaacatt
     7261 ggctttggcg gcggcaagcg catcctgcgc gctttccaaa tcttctttag aggtcgcatc
     7321 atccttccac aacgccgcct ggcgtttgta tttcttctcc gcgctgccca atgcaatctg
     7381 tgccgacacc agcttcgcct gatacgtttc caatttggat ttttccatat tgagcgtgtt
     7441 ggtctgcgtg gtcgaattga tttccgcaat caaatcgccc tttttaacct gttgcccgag
     7501 ccggacataa agtttcttaa tctgccccga tgcctgcgcg ccgaccgata ccaggttgga
     7561 cggcgaaatc tcccctgttg cagaaaccgt ctggctgatg tcgccgcgcc tgaccgtttc
     7621 cgtaatataa gaagcctgcg gttcgggctt cagataagac catccgcccc aaaccgctgc
     7681 cgccgcgacc gccgcaacag ccgcccattt catcattttt gccatgtttt caattctctg
     7741 tatgcgtcaa tcccataaat cggaagcgga ttctaccgca agtccctgcc ccatccaagg
     7801 cggcaaactg ccgacaataa aaataaccat ttgttttaaa tggcttatac aatctgcttt
     7861 cccgaaaatt tcaatccgtt tacatattcc gccatttccg atacggcgtt ataatgtcgc
     7921 cgaccgacaa acaaatggaa acacattgct atgaaaaacg ttcaaaaagg ctttacgctg
     7981 ctcgagctga tgattaccgt cgccatcctc ggcatcctga cgctcatcac ctacccttcc
     8041 tataaaacct acatccggcg cgtccgcctg acggaagtca ggacgaccct gctgcacaac
     8101 gcgcagacca tggaacgtta ctaccgccaa aaaggaacgt ttgaacacta caatctgacg
     8161 aaactggaac aaaacgaata tttcgatatc actttaagcg aagtcagccc cgaccatttt
     8221 acccttaagg caacgcccaa tcccaccacc aacgacggcg aaacctgcgt cgttacgctc
     8281 aacgacggcg gtaccattgc cgcttccggt acaaaccaat cctgccccgg cttcgactaa
     8341 tcctccgccg aagcccgcaa acccgtaaag atgccgtccg gacacagctt cagacggcat
     8401 ttttacgggt ttgccgtccg gtttttcaaa cttgaaacct gccgcccctc atccggcaac
     8461 cgccccgatg ccgcgccttt ccaactgtta taatataaca tataacccat atttttcaac
     8521 aacataccac ttgacctgtg agatgcggaa gcgtatgctt acccttatat cggacaacat
     8581 tccgtttaca ggtttttttg ccgtaactaa ggagcgcaat catgaaaatg caggcagttg
     8641 ttgtgaataa aaatgtagcg ggcgatgtgg aaatagtcga acgcgaggtt cgcccgttga
     8701 aatacggcga ggcgttggtc gaagtcgaat attgcggcgt gtgccacacc gacctgcacg
     8761 ttgcggcagg cgactacggc gaaaaaccgg gccgcgtgct gggacacgag ggcatcggtt
     8821 tggttaaaga agttgccgac ggtgtgaaaa atctgaaagt cggcgaccgc gtcagcatcg
     8881 cctggctgtt ccaaagctgc ggctcgtgcg aatactgcaa taccggccgc gaaaccctgt
     8941 gccgctctgt attgaacgcg ggctacaccg ccgacggcgg tatggcgacc tactgcatcg
     9001 tgagtgccga ttacgcggtc aaagtccctg aaggtttgga tcctgcgcaa gcttccagca
     9061 ttacttgtgc cggcgtgacc acttataaag ccattaaagt ttccagtgtt cgtccgggac
     9121 agtggattgc catctacggc gcgggcggtt tgggcaactt gggggtccaa tacgcgaaaa
     9181 aagtatttgg cgcacacgtt gtcgccatcg acatcaacga cgacaaactg gcgtttgcca
     9241 aagaaaccgg cgcggatttg gttgtcaacg ccgccaaaga agacgctgcc aaagtgattc
     9301 aggaaaaaac cggcggcgca cacgctgcgg tcgtaaccgc cgtatctgct gccgcattca
     9361 actctgccgt gaattgcgtc cgcgcaggcg gacgtgtggt tgccatcggg ctgccgccgg
     9421 aatcgatgga tttgtccatc ccgcgtttgg ttttggacgg catcgaagtg gtcggctctt
     9481 tggtcggcac gcgcaaagat ttggaagaag ccttccaatt cggcgcggaa ggtttggttg
     9541 tgccgaaagt ccaactgcgt gctttggatg aagcacccgc cattttccaa gaaatgcgcg
     9601 aaggcaaaat caccggtcgt atggtaatcg atatgaaaaa agaatgcggc tgcggccacc
     9661 accactgatt tgacgtggcg atacacatcg aaatgccgtc tgaacgctgt tcagacggca
     9721 ttttttatgg atttggattt gattttaatc tgttctgttt gaaataccgt ctgaaaaccc
     9781 ttatcgcaac acgtcattat agtggattaa caaaaatcag gacaaggcgg cgagccgcag
     9841 acagtacaaa tagtacggaa ccgattcact cggtgcttca gcaccttaga gaatcgttct
     9901 ctttgagcta aggcgagcca acgctgtacc gatttaaatt taattcacta taccgtctga
     9961 caacccgtat cgcaacactt cattaaaaac ggcaagattc agccgttctg caacccgttc
    10021 aaacggattc cgccatttcc aacgcctgtt tgatgtccac ggcgacgacg cgcgatacgc
    10081 ctttttcctg catggttaca ccgaccagct gttccgccat ttccatggtc aggcggttgt
    10141 gggagatgta gagaaactgg gtttgcgccg acatttcttt gaccaggttg cagaaacgcg
    10201 aagtgttggc atcgtctagc ggagcgtcga cttcgtccaa aagacagaac ggagcggggt
    10261 tgaggctgaa cagggcgaac acgaggctca tcgcggtaag ggctttttcg ccgccggaaa
    10321 ggaggtggat ggtgctgttt ttcttgccgg gcgggcgcgc catgatagac acgccggcgg
    10381 tcaaaaggtc gtcgcctatc attttgaggg tggcttcgcc gccgccgaac agggtcggga
    10441 agaaggtttg gactttgccg ttgacggcgt cgaaggtttc tttgaaacgc gctttggttt
    10501 tgtcgtcgat ttgggcgatg gcttcttcca aaagggtgat ggcggtctgc acgtcttcgc
    10561 tttggctgcg gtagtagccg tcacgttcgc gcgcttcttc gagttcttgc agggcggcga
    10621 ggttgaccgc gccgagtgct tcgatttgtt gcgaaaggct gccaatgctg ctgttcaata
    10681 ctttcggcga ttctttcgcc aacgcttcga gcgcgtccaa atcggcggcg cgttcggtca
    10741 ggttttgatg gtagcgtttg gcgttgatca gggcttcctg ctgctgcaac agggcggttt
    10801 gggtggcggc ctgaagctgc ggcagcttgg tttgcagggt ttgtacgcgg gcgtattgtt
    10861 ccctaccctg ctcctgaatc tgcgcgagtt tctcctgtac gacaatatat tcttcgtcca
    10921 aactctgtac ggcttcgctc aactcttcga gcttgatgtg ctgctcgtcg ttttggaact
    10981 cggtttcata ggcgagggca agctcttgct ggcgttcctg ccaatcgaag gtttgttgtt
    11041 caagctgggc aatttgctgt tggtagtttt gtttttgctg gttgagcttg tggacggcga
    11101 cttcggcaag cccgtattgg cggttggctt ccaacagggc aagctgcgcc tgtttcagac
    11161 gaccttgctg ctcttggcgg ctgtgcgcgg cggtttgctg ctggtgttcg agttcggcgg
    11221 cggcttcctg caaaatggcg atgtcgtctg aaagcccgtc ggacgtgtgt tgcaacacgg
    11281 tctgctcttc cgccaactgc gccagttcgc gctcgatgtg ttcgcggcgg atttgccctt
    11341 ggttggtgcg cgccagaagt tcggcggcgc gttgctgcgc ctgactgtat tggcgcgtgt
    11401 gctgctgttg ttgctgcatc aggtttttgt gctgcacttc ggacgagcgc acggcggctt
    11461 ccgcctgttt gaacgcggct tcggcggcgg agagttcggg ggctaggttg tccagttcgg
    11521 atgcgatgcc gtcgaggtgc gctttttggg caatcaggct ttcctgcgcg ggcttggcat
    11581 agagcaggac gctgacctta tcgacctgat gaccttcggg cgtgagccag atttggtgtg
    11641 cgcccaaatc gttttgatgc gcgagggcat agctcaaatc gggcgcgcac aatacgccgt
    11701 cgagccagtg gtgcaatgcc gtctgaaacg gcggctgcgc ttggatttgg ttcagcaatg
    11761 cctgtacggg cagggatttt ttgatgccgc cggagagacc gtctgaaagc cacgccgcct
    11821 gcccctgcgg caaaggttcg ggcggtacga aaccttgcgg cacgtcgcgg gcgtgcaggc
    11881 gttcggcaag gatgacggac agggcgtgct gccactcagc aggcgcggta atgtgttgcc
    11941 acagttgcgg cgcggcggcg tggccggttg cctgccagaa atcggctgct tcctgctgtt
    12001 gcgacaggat ttgcgacaac gcctgctgct gcgcctgcaa ggtgatatgt tgctgcttca
    12061 ggctttggaa gcggtttgag gccgtctgaa acgcctcgcg ggcggcgtgt aaggcttctt
    12121 cggcggcgat gatttgttct tcgtaatgct cttgccggct ttgcaacaag gcagcggcct
    12181 cctgcgcggc ggcggtttcc gcttcgtcgg gcaggttcag ggcttggttc tcctgtttca
    12241 gacggccttt gcgctcttcg tgcttggcaa cggtttgttc ggcatgggca agctgctgct
    12301 gcttcaacgc cagttcgcgg cggatgcggt ttgcctcgtc ctgctgggtt tggaaggcgg
    12361 cattgagcgc ggtttgggtt tcttccaatt cgggcagacg ctcttcgtgt tcggcaacct
    12421 gcatcgccca ttccgccagc tcggtttgct tttcttcgac ctgcgactcg ttttcttcca
    12481 gcttgacgcg gatttgctgc tgctcctgat ggatgcgttg catctgcgcc tgcgctgcct
    12541 gcttgtcgcg ttcgatgcgt tggtgcaggt tttgctgatg gcggatttgt tcttccaaac
    12601 gggcaatctg ctcgcgcaac acgccgcgtt tgttgcccag ttcgtgtacc gcctgctgct
    12661 gcgattgttc ggtggtctgc aaggcgtgta cttcgtcgtt taacgcctga acctgcgcgg
    12721 cggtttcgtc ctgctgcgcc tgcaaagact gatgctgcgc ggtcgccttg tcggcggcgg
    12781 caagcgattg ctgccattgg gcgtaatcga gcaaatcctg ctgttggttc aactgcgcgg
    12841 tcagggattt gtagcgttcg gcggtttccg cttgtttttc cagcttttcc acctgacgcg
    12901 ccaactcgtt ctgcaaatcg cccaaacgct gcaaatgctc gcgcgtgtct ttcagacgac
    12961 cttccgtctc cttgcggcgt tccttatatt tggacacgcc cgccgcctcc tcgatatagg
    13021 cgcgcaactc ctccggccga gcttcgatga tgcgcgaaat catcccctgc tcgataacgg
    13081 cataaccgcg cgcgcccacg cccgtaccca gaaacaaatc agtaatatcg cggcggcgca
    13141 cggtctgatt gttgatgaaa tatgtcgatt cgccctgacg cgtcaactgc cgcttgatgc
    13201 tcacctcggc atactgcccc cacgccccct gcaaactgtg gtcgctgttg tcaaacacca
    13261 gctccaccga agccctcggc gcaggacggc gcgtcgccgc accgttaaaa atcacgtcct
    13321 gcatactctc gccacgaagc tgcttcgccg aagcctcgcc caacacccag cgcaccgcgt
    13381 caatcacatt cgacttgccg cagccgttgg gcccgataac cgcgacaagc tgccccggaa
    13441 catgaatcgt ggtcgggtcg gtaaaagatt tgaagccgga gagtttgatg tgggtcaggc
    13501 gcataatggt cggaaaaaat aaaaaagaag cgtattttaa cggaaatccc gccgcaccac
    13561 cccatatctt gccggcaaaa ccttaccgca tcccgcaccc tcgatgccgt ctgaagcctt
    13621 cagacggcat ttttaacgcg cccgaacccc gattccgcca acgcccgatg cttggcgcgg
    13681 catttgccgt attgccccgc cgccgggcgc gttataatcc gccacgacat ccgcccgatt
    13741 tggaaacctg cctatgaaac ccgcctattt catctccgac ctgcatttga gcgaaaagca
    13801 ccccgaactg accgcgctgt tgctgcgttt tttacgttct tccgccgccg ggcaggcgcg
    13861 ggcggtttac attttgggcg atttgtttga tttttgggtg ggcgatgacg aagtttccga
    13921 gttgaatact tcggttgcgc gtgaaatcag gaaattgtcc gacaaaggcg ttgccgtgtt
    13981 cttcgtcagg ggcaaccgcg acttcctgat tggtcaggat ttttgccggc aggcaggcat
    14041 gacgctgctg ccggattact cggttttgga cttgttcggc tgcaaaaccc tcatctgcca
    14101 cggcgacact ctgtgtacgg atgacagggc ataccaacgt ttccgcaaaa tcgtgcatcg
    14161 gaagcggctg caaaaactgt tcctgatgct gcccctgaag tggcgcacgc gccttgccgc
    14221 caaaatcagg cgcgtcagca aaatggaaaa acaggtcaag cccgccgata ttatggatgt
    14281 caatgccgcc tttaccgcgc ggcaggttcg cgcctttaac gcggaaaggc tgatacacgg
    14341 acacacccac cgcgagcata tccatcacga aaacggcttt acccgcatcg ttttgggcga
    14401 ctggcataac gactatgctt caatcctccg cgtggacggg gacggcgcgg tattcgtgcc
    14461 gctggaaaaa tgctgaaaat gccgtctgaa gcctttcggg cggctttttt tacacgcccc
    14521 tttcccacac tccctccgcc gcatcatcac catccttaac ccgcattaat gggcgttatc
    14581 gataaaatgc ttgaccgatt acataagatt acgtaaagtg tgcaaacgca taacaattgg
    14641 tcttaccaat ttatctttta accaaaatat cgggtgtacg ggatttgaac gtctttccaa
    14701 acctcgacgc gccttatgat gcaaatgcct aaaaaggatt cgttatggca cttttcctca
    14761 gcatattccc catcgtcctg ctgatttggc tgatggtgaa aaaaaacagt atgccctcct
    14821 acgtcgcgct gccgattacc gcagtgctga tttacgccat caaacttttc tacttcggcg
    14881 atgcgggcat gctgctcaac gccaccgccg cttccggcct cgtcaaaacg ctcacgccga
    14941 ttaccgtgat tttcggcgcg attatgttca accgtatgat ggaaaccacg ggctgcattg
    15001 atgtcatccg caaatggctg gcgaccatca gccccaaccc cgtagcgcaa ctgatgatta
    15061 tcggctgggc ttttgccttt atgattgaag gcgcatccgg cttcggcacg cctgccgcga
    15121 ttgccgcgcc gattctgatg agcttgggct tcaacccgtt gaaagtggcg attttcactt
    15181 tggtgatgaa ctccgtcccc gtctctttcg gcgcggtcgg tacgccgacc tggttcggtt
    15241 tcgcaccgct gaacctgagt gccgaagaca tcctcgccat cggcaggcag accggcgtaa
    15301 tgcacttctt cgcaggtttc gtcatccccg tcatcggctt gggcttcatc gtaccttggt
    15361 ctgaaatccg caaaaacttg ggcttcgtcg ccattgccgt cttctcctgc accattcctt
    15421 atgtcgcatt ggcgatggtc aacgaagaat tcccgtcgct cgtcgccggc gcaatcggcc
    15481 tgatggtgtc cgtattcgcc gccaaccaag gctggggctt gagcaaagac cacgccaaag
    15541 acccgaatgc cgaaaaagtg ccgttcgccc aagtcgccaa agcactcgcc cctttgggta
    15601 tgctgatcgg catgctggtg gttacgcgca tcaaacagct cggcatcaaa ggcattttga
    15661 ccagcaaaga agaatggttc agcttccaac tgccgtttga tttgtccaaa atcaccgtca
    15721 gcgactccct gacgattacc ttcggcaata ttttcggaca agatgtcagc gcgtcttacc
    15781 aaacgctgta cgtcccggct tggattccgt ttgtgctgac cgtttggatt tgcatcctgc
    15841 tgtataaaac caaattcaaa gatgcctgga cgatttatgc cgtaaccttc aatcaaacca
    15901 aaaaaccgct gcttgccctg atgggcgcgc tgattatggt tcagctgatg ctggtcggcg
    15961 gcgacaattc gatggtgaaa atcatcggta aagaatttgc cgcaatggcg ggcgaacact
    16021 gggtttattt ctcgccgtat ttgggcgcga ttggcgcgtt cttctccggt tccaacaccg
    16081 tgtccaacct gaccttcggc ccgattcagc agcaaatcgc cttggatacc ggcctgtccg
    16141 ttaccctgat tctggcgttg cagtccgtcg gcggcgcgat gggcaatatg gtgtgcctca
    16201 acaacatcat cgccgtatgt accgtattgg atgtgaaaaa ttccgaaggt gcgattatca
    16261 agaaaaccgt tatcccgatg gcgatttacg gcgtgattgc cgtcgtcgcg gcaatgattt
    16321 tcttcctcta ggcgaaacgc caccatccat agcggcagca cgcggggaac ggaaaccgcc
    16381 gttccccgtc tgggcggcgc gtcgggcaga atcccggtgc cggaacaagc ccgccccgcc
    16441 aaacaaatgc cgtctgaaac cggaaaaggc ttcagacggc atttttccgc cgcttgcgtt
    16501 caggcgtaat gatgatgcgg catcttgccg tcaaggcggt agcgcgtgcc gcaatacggg
    16561 caggcaacgc tgcccgattc tccttcgcac aaaggcaaaa acactctcgg atgcccgttc
    16621 cactgctcgt tgtcgggtcc cgagcaatac agcggcagat tttccggcaa cacggaaatt
    16681 tcctgcagat tcagattgtc catttgattt tcctttgcgt ggttggcgtg cgcccatttt
    16741 acgccatcgg caggctaaag gatattttcg gcgcaaagcc gcaatccgct ataatcccca
    16801 cttttcagac ggcataccat gactgcgctt acccttccgg aagacatccg ccaacaagaa
    16861 ccatccgttc tgctctatac cctcgtttcc gcctacctcg aacacaccgc ccaaaccggc
    16921 gacgaatccc tctcctgcct gtccgacgac cagcacacgc tgaccgcatt ctgctacctc
    16981 gacagccaag tcgaagaagg cggcttcgtg caactcatcg cctccggtta cggcgaatat
    17041 attttccgca acccgcttgc cgacagcctg cgccgctgga aaatcaaagc cgtgccgaaa
    17101 gtcttggaca aagccaaagc cctctacgaa caacacggcg aaaccatcga aacgctcgcc
    17161 gacggaggcg cagacatcga atccctgcgc aaacagttcc ccgactttga agaatgggac
    17221 ggcgcatact acgaagccgc cgaacaagac ctgcccctgc ttgcagaaca catcctgtca
    17281 aactgggaaa ccttcgccca tatcgggcag gcgtgattgc gtctgtttcc agcccgtgta
    17341 aaacagcgta aaatcggcaa acccgaatga ccttccgtcc ccatcaagga gcaagctatg
    17401 ttcttcaagc acatcgaagc cgccctcgcc gatccgattc tcggtttggg cgaagcattc
    17461 aaagccgaaa cccgccccga aaaagtcaac ctcggcatcg gcgtttataa agacgcatcc
    17521 ggcgcgacac ccattgtcaa agccgtcaaa gaagccgaaa aacacctgtt ggaaagtgaa
    17581 accaccaaaa actacctcac catcgacggc gttgccgatt acaacgcgca aacccaaatc
    17641 ctgctgttcg gcaaagacca cgaaatcatc gccagccgcc gcgccaaaac agcgcaaagc
    17701 ctcggcggta cgggcgcatt gcgtattgcg gccgagtttg ccaaacgcca gttgaacgcg
    17761 caaaccatct ggatttccaa tccgacctgg ccaaaccaca acgccatcgc caaggcggtc
    17821 ggtatccaag acaaacctta tcgttattat gatgccgcca aacacggttt ggattgggac
    17881 ggtatgattg aagacttgag ccgggcgcaa aaaggcgaca tcgtcctgct gcacggctgc
    17941 tgccacaatc ctaccggcat cgaccctacg cccgaacaat gggaaacttt ggcaaaactt
    18001 tctgccgaaa aaggctggtt gccgctgttt gactttgcct accaaggctt cggcaacggt
    18061 ctggaagaag atgcctacgg cttgcgcgtg ttcttgaaac acaatacaga attgctgatt
    18121 gccagctctt attccaaaaa cttcggtatg tacaacgagc gcgtcggcgc gttcactttg
    18181 gtggccgaag acgaagaaac agcaatccgc gcacacagcc aagtcaaaac catcatccgt
    18241 accttgtatt ccaacccggc ttcacacggt gcgaacacca ttgcgctggt gttgaaaaat
    18301 gatgatttga aagcccaatg gattgccgaa ctcgatgaaa tgcgcggccg catcaaagcc
    18361 atgcgccaaa aatttgttgc gttgctcaaa gccaaaggtg caagccaaga ctttgatttc
    18421 attatcgaac aaaacggtat gttctctttc agcggtctga ctcccgaaca agttgaccgt
    18481 ttgaaaaacg agtttgccat ttatgccgtc cgctccggcc gcatcaacgt cgccggcatt
    18541 accgacgaca acatcgatta tctgtgcgaa agcatcgtga aagtcttgta aaacaaaagc
    18601 gcatacgaaa tgccgtctga accttaacca gttcagacgg catctgtttt ttgttaaaaa
    18661 acaataaacc ataacaattt caaacaagct aaaaaacatc tataaaatca acccaatatg
    18721 atgaactcaa ataaaaaata cgaatatcat cattctcaaa ttcaaaattt gaacgccaca
    18781 gtattatccg aagccacaaa aacctttccg ccgtcattcc cgcgcaggcg ggaatccggg
    18841 aacccaatgc tgcaagaatt gattagaaac aactgaaacc gagcaaactg gattcccgcc
    18901 tgcgcgggaa tgacgaaata aggcgagtaa aactgatgaa acaaattgat taaaaacaat
    18961 aacttatatt attttattta aattttcgat aaaatcaatt ttccgtattc aatactgctc
    19021 caatcaattc ccgcgcaccg tcgtccgcca atttcttagc gacagcgcgt ccgagcgcgt
    19081 cggcatattc ggcaggggct tgcgcgtccg cccgcaacac aaccgaaccg tcgggatgac
    19141 cgaccaagcc gcgcaaggtc agcaagccgt tttcttccgt gcaatatgcc gccagcggca
    19201 cttggcagct tccgcccaaa gcgcgcgcca acgcgcgttc agccgtaacg caggcgtgtg
    19261 tggtatcgtg gttcaacggc tttaagactt catacaaatc ttcgcgatgc gctgcaattt
    19321 caatacccaa tgcaccttgt ccggcggcag gcagactgtc agattccgac aaaatcatgc
    19381 ggatgcgttc gtccaattcc agacgctgca aaccggcggc ggcaaggata attgcgtcgt
    19441 attcgccgtt atcgagtttg gacaaacggg tttgcacatt gccgcgcaaa ggtttgataa
    19501 ccaaatgcgg atagcgcgca cgcaactggg cttcgcggcg caggctggat gtaccgacga
    19561 cagcgccttt gggcatttct tccaaacgcg cgtattggtt ggacacaaac gcgtcaaacg
    19621 gattggcgcg ttcgccgatg gcggcaagcg cgaaaccttc aggcaaatcc atcggcacgt
    19681 ccttaatcga atgcaccgcc aaatcggcgc gcccgtcata taaagcctgt tccaactctt
    19741 tgacaaacaa gcctttaccg ccgacttttg acaaagtttt gtccaaaatc tgatcgccgc
    19801 gcgtggtcat gcccaaaatc tcgacttcgc aatcgggata cagagccttc agacggcctt
    19861 ggatatgctt tgcctgccac atggcaagca ggctttcgcg gctggcgatg acgagttttt
    19921 tcgggttcat gttcaatgcg ttcaaagaat ggaaacggcg tgaagtctat catattttga
    19981 acgtttcttc agacggcacc gtcaggtcta tgttatattt acacccacaa aacacgaaac
    20041 ccgccacaat gaaacgcacc aaaaaatacc ctttcttaac gttgcagcgg caacgtttcc
    20101 atttgaactt tgaaaacgcc tcttccgccg ccggcatccc agccgaacgc gatttctacc
    20161 gctgggcgtg gtctgccttg aaaagcggat accgccgcgc cgacatcagc ctgattcttc
    20221 tggacgaaga agaagcccga gcctacaacc gcgactaccg cggcaaagat tacgccacca
    20281 atgtattgag tttcgcgctc aacgaaggcg aaatcctgcc ctgccaagtt tcggaaaaac
    20341 tgtacggcga tttgattatc tgcccgcaag tggttttgaa agaagccgcc gaacagggca
    20401 aaacgcccga acggcatttt gcccacctga ccatacacgg cgttttgcac ctgatgggct
    20461 acgaccacat cgaagacgat gaagccgaaa taatggaagc cgaagaaatc cgcctgatgc
    20521 tggcggcagg cttccccaac ccctaccaag aggacgaata ttaaaatgga cggtacgcag
    20581 tcgaaaccca agtttttcga acgcctgatc tcccgacttg ccggcgagcc cgactccgcc
    20641 gaagacgtat tgaccctgct gcgccaagcg cacgagcagg aagtttttga tgcggatacg
    20701 cttttaaggt tggaaaaagt cctcgatttt tccgatttgg aagtgcgcga tgccatgatt
    20761 acgcgcagcc gtatgaacgt tttaaaagaa aacgacagca tcgaacgcat caccgcctac
    20821 gttatcgata ccgcccattc gcgcttcccc gtcatcggtg aagacaaaga cgaagttttg
    20881 ggtattttgc acgccaaaga cctgctcaaa tatatgttca accccgagca gttccacctc
    20941 aaatcgatat tgcgccctgc cgtcttcgtc cccgaaggca aatcgctgac cgccctttta
    21001 aaagagttcc gcgaacagcg caaccatatg gcgatcgtca tcgacgaata cggcggcacg
    21061 tcgggtttgg taacttttga agacatcatc gagcaaatcg tcggcgacat cgaagatgag
    21121 tttgacgaag acgaaagcgc ggacaacatc cacgccgttt cttccgaacg ctggcgcatc
    21181 cacgcggcta ccgaaatcga agacatcaac accttcttcg gtacggaata cagcagcgaa
    21241 gaagccgaca ccattggcgg cctggtcatt caagagttgg gacatctgcc cgtgcgcggc
    21301 gaaaaagtca ttatcggcag cctgcaattt accgtcgcac gcgccgacaa ccgccgcctg
    21361 catacgctga tggcgacccg cgtgaagtaa gcagagcctg cccgcaccgc cgtttctgca
    21421 cagtttagga tgacggtacg gacgttttct gtttcaatcc tccccatccg ccaaacataa
    21481 aaatgccgtc tgaaaccgga aaacaggttc agacggcatt tcgcttatcc gcttattttt
    21541 tgctcaaagt cagccccgtc cagccgaata acagggttaa agccaaactc aaatagcaga
    21601 aaaaggcata gggcagatat tcccagaccg gcacacccag cgcatggctg ataaatacgc
    21661 cgcacacgct ccacggaaca agcgggttga tgaccgtacc cgcgtcttcg agcgtacgcg
    21721 agaggttgcg ggaatgtagt ccgagcttat cgtaaacggg tttgaacgtt tcacccgaca
    21781 acaaaatact caaatattgc tcgccgatca ggaaattaac cccgaccgaa gtcatggcaa
    21841 cgctgaatgt ggcacgtccg gcattcgtca aaaagctgcg gacggcatcc agcagggaag
    21901 gaatcgcgcc cagcgcaaac agcagcccgc ccaaactcat cccgagaatc acgatggttt
    21961 gcgtgaaaaa catactttcc aagccgccgc gcgaaatgag tttggcgatg tctttaaacg
    22021 cttcgccttc gagtttgtag ccgccgtaaa accacgcgcc gagctgacgc agatcgggcg
    22081 tgctgtgcag atacgttacg gcaacggcgg caatgacggt aaagagcata gcgaccacgg
    22141 cattgacgcg catcaatgcc aaaacgacca acagcgcaaa cggaatcagc gaatagcagt
    22201 gcaccaatcc cgtggcttca agctggctgc ggaaggattc gacgctgttc aaatcctgcg
    22261 cggcgacgct gggaagaagc cacagcatca gtgccgcact gatgagccac gcgggaatgg
    22321 tggtgtacat catatttttg atgtgttcaa acaggtcgat accgacaatg gacgcggaaa
    22381 tgcccgtcgt atcggaaagc ggggacattt tgtcgccaaa aaatgcgccc gaaacaatcg
    22441 cgcccgccgt catcgccata tcggcctgaa acgccgccgc catacccata aaggcaacgc
    22501 cgacagtggc gcaggtggtc aggctgctgc cgatggacac gccgatgacg gaacacagcg
    22561 cgaaggcgga aaaataaaaa taagtcgggg aaatcagtcc gaaaccgtaa tacatcagcg
    22621 tcggaatcgc gccgctcatc atcagcgcgc tgaccatcag cccgatgaag aaaaacaggt
    22681 aaatcgcgcc cataccctga ttcaacgcgc ctatcatgcc ctgctgcata tcgttgtatt
    22741 tcaaaccgcg cgccaagccg tacaaaatca gcacgacgat ggcggcaata atggacatat
    22801 gcggcagcca ctccaatgaa atgatggtat agcccatcgc ggcaatcaga gcgacgacga
    22861 cggcaagtgc ctcaccgcgc ggcatatcga gtaaggattt gaaagcgaac atgattcttt
    22921 gcccgatttg atataaagtt aacggattct aacacaccat accgaatccg cccgacgttt
    22981 tcagacggca ttttagcgtt ttacaaaagc cggacagaaa caaaacggca attttctcaa
    23041 tttaaattaa tttttttgaa atataatttt ttattttttt gtttgttgac atataagact
    23101 tttatggatt gaagtattaa aacctcggca cacacgccgc aaacaccggt acgcaaaaat
    23161 gccgtctgaa agatgttcag acgacatttc tcaagaaaaa gattatttgt ccgccctata
    23221 tccgtacacc gcaaaaaaca cgatatacag ataacagatg acggaaacga caaacgaaga
    23281 catcagggtg taagtatctg ccacccagcc ctgcacgaca ggaacgaccg caccgccgac
    23341 aatcgcggta cacagtacac cggaagccgc gttggtaaat tttcccaatc ctttggttgc
    23401 caaagagaaa atcgtcggga acataatcga gttgaaaaaa ccgatggcaa gcagcgacca
    23461 catcgccaca tccgcattgc cgctacccgt cgccatcgcg acggcaagca gtacgaccgc
    23521 agccgatgcg ttaaacgcca aataacggtt gggcgcgaat ttcgccatca ccgccgaacc
    23581 gaggaaacgt ccgaccatcg cgccgcccca atagaacgac aggtaatgcg cggcagaagc
    23641 atgatccagc cctttcagat aacccaatac gttgaccatc aacgaaccga tagacacctc
    23701 cgcgccgaca tagcagaaaa tgcctgccgt accgaacacg agatgtttgt attgccatac
    23761 gctggttttg ccgtcgtggt tgtgcgcgct ttcctcggcg gcaattttgc gcgcgtcggg
    23821 cagccggatc attttcacga aaacggcaag gataatcagc agccccgcca gtcccaaata
    23881 gggaatctgt acggaagaaa tctgttccgc cttgctgacg gtttgggttg cgtccgccag
    23941 aatcaggaac gcgccgattt gcggcgcaat ggtcgtaccc aaagcgttaa acgcctgaac
    24001 cagcgtcagt gttgccgatt ccttgccggg tttcgccagc agggtaacat aaggattacc
    24061 ggcgacctga agcagcgtta cgccggaagc caaaataaac aacgcgccca aaaataccgc
    24121 gtaagaatgg ctacccgcag caggataaaa cagcaggcat ccgaccgccg tcagcagaaa
    24181 gccgccgata acgccgtttt tgtagccgac tttgccgaca aaagccccca tcgggatgga
    24241 catcaccgca taggcggtaa agaaacagaa ttggatcagc atcgcctgaa cgtaagacag
    24301 gtcgaaaatt tctttcaaat gagggataag gatgtcgttc atgcaggtaa taaaacccat
    24361 catgaagaac agcgtggtca agacgaccaa tggggacgta tgattgtttt gtgattgcgc
    24421 agacatgatt tgcctttcgt ggtgtcggaa tattacccgt ttcaagaaaa tagaaattga
    24481 catttcttaa cggcaatgca aatcatactg atatttgaac attttgcaaa ctttatcgga
    24541 tgcaggcaat gcgccgatct gaaattcaag cagcagaaat taatatttta cagttgcttg
    24601 catagatttt aatagatttt aaaaaattcc ggcggacttg caaaaaccgt tcccaataaa
    24661 atgaaaatcc gccgccgtat ccggaaaatt cggaaatgcc gcatcgtggc atcaaaaccg
    24721 gagcggaaag aatgtcgtat gcccgacaaa aaaggggcat acggctgtgc cgtatttttt
    24781 gcaccgtcct ccgcccttcg gcgggggcgt gaaaatatag tggattaaca aaaatcagga
    24841 caaggcgacg gagccgcaga cagtacaaat agtacggaac cgattcactc ggtgcttcag
    24901 caccttagag aatcgttctc tttgagctaa ggcgaggcaa cgccgtactg gtttttgtta
    24961 atccactata ccgtacaatc cgtcgccgat ttttgcctgt ttgagactgt ttgcaatgat
    25021 gcccgcctac gcctacgccg cgctcgcttt ttccgccttc acttccgcca ccctcctgcc
    25081 cggcacatcc gaagccgcct ttgccctgtt cgtccaccgc tttcccgaac acgcatacgg
    25141 cgcgttgctg tgcgccggcc ttgccaacgg attgggcagt atggtttcct attggatggg
    25201 gcgtttgctg ccctcccgaa aaatgccgtc tgaaaaaaca ctgaatctga tgcggcgttt
    25261 cggtatttgg ctgcttgcgt ttgcctggct gcccgtcgtc ggcgacgcac tgccgcttgc
    25321 cgccggctgg ctgcggttga atccgtggac aagcgggctg atgctggtta tcggcaaaac
    25381 ggcgcgttac gccttcattc tgtggggaat gcaatattac gccgcctgaa ccatacgtta
    25441 taatgccgaa cacacaaacc caccgtataa aaaaatgaac agacacatcc gccaagaaat
    25501 cttcgaacgc ttccgcgccg ccaaccccca tccgaccaca gaactcaact tcaactcccc
    25561 tttcgagctt ttaatcgccg ttttactgtc ggcacaggca accgacgtcg gcgtaaacaa
    25621 agcgacggcg aagctgtttc cggttgccga tacgccgcag gcgatgctgg atttgggttt
    25681 ggacggcgtg atggaataca cgaaaaccat cgggctgtat aaaaccaagt ccaagcacat
    25741 catgcaaacc tgccgcatcc tgctggaaaa atacaatggc gaagtgccgg aagaccgcga
    25801 ggctttggaa tcgttgccgg gcgtggggcg caaaacggca aacgtggtat tgaacacagc
    25861 gttcggacac cccgttatgg cggtcgatac gcatattttc cgcgtgtcca accgaaccaa
    25921 aatcgccccc gggaaagatg tgcgcgaagt cgaagacaaa ctgatgcgct tcattcctaa
    25981 agaatttctg atggacgcgc accactggct gattttgcac ggacgctaca cctgcaaggc
    26041 actcaaaccg caatgccaaa cctgcatcat caacgatttg tgcgaatatc ccgccaaagc
    26101 ctgaccgccg ccgcccttca aaatgaaacg cttgaaaatt cggacggacg ttgtagaatt
    26161 tcaacctatg ccgtctgaag ccgacaaaat gcgcttcaga cggcattaaa gccggtaccg
    26221 gcatccgaca aaggacaaaa cgtgttcaaa aaataccaat acctcgcttt ggcagcactg
    26281 tgtgccgcct cgctggcagg ctgcgacaaa gccggcagct ttttcggtgc ggacaaaaaa
    26341 gaagcatcct tcgtagaacg catcaaacac accaaagacg acggcagcgt cagtatgctg
    26401 ctgcccgact ttgtccaact ggttcaaagc gaaggcccgg cagtcgtcaa tattcaggca
    26461 gcccccgccc cgcgcaccca aaacggcagc agcaatgccg aaaacgattc cgacccgctt
    26521 gccgacagcg acccgttcta cgaatttttc aaacgcctcg tcccgaacat gcccgaaatc
    26581 ccccaagaag aagcagatga cggcggattg aacttcggtt cgggcttcat catcagcaaa
    26641 gacggctata ttctgaccaa tacgcacgtc gttaccggca tgggcagtat caaagtcctg
    26701 ctcaacgaca agcgcgaata taccgccaaa ctcatcggtt cggatgtcca atccgatgtc
    26761 gcccttctga aaatcgacgc aacggaagag ctgcccgtcg tcaaaatcgg caatcccaaa
    26821 gatttgaaac cgggcgaatg ggtcgccgcc atcggcgcgc ccttcggctt cgacaacagc
    26881 gtgaccgccg gcatcgtgtc cgccaaaggc agaagcctgc ccaacgaaag ctacacaccc
    26941 ttcatccaaa ccgacgttgc catcaatccg ggcaactccg gcggcccgct gttcaactta
    27001 aaaggacagg tcgtcggcat caactcgcaa atatacagcc gcagcggcgg attcatgggc
    27061 atttccttcg ccatcccgat tgacgttgcc atgaatgtcg ccgaacagct gaaaaacacc
    27121 ggcaaagtcc aacgcggaca actgggcgtg attattcaag aagtatccta cggtttggca
    27181 caatcgttcg gtttggacaa agccggcggc gcactgattg ccaaaatcct gcccggcagc
    27241 cccgcagaac gtgccggcct gcgggcgggc gacatcgtcc tcagcctcga cggcggagaa
    27301 atacgttctt ccggcgacct tcccgttatg gtcggcgcca ttacgccggg aaaagaagtc
    27361 agcctcggcg tatggcgcaa aggcgaagaa atcacaatca aagtcaagct gggcaacgcc
    27421 gccgagcata tcggcgcatc atccaaaaca gatgaagccc cctacaccga acagcaatcc
    27481 ggtacgttct cggtcgaatc cgcaggcatt acccttcaga cacataccga cagcagcggc
    27541 ggacacctcg tcgtcgtacg ggtttccgac gcggcagaac gcgcaggctt gaggcgcggc
    27601 gacgaaattc ttgccgtcgg gcaagtcccc gtcaatgacg aagccggttt ccgcaaagct
    27661 atggacaagg caggcaaaaa cgtccccctg ctggtcatgc gccgtggcaa cacgctgttt
    27721 atcgcattaa acctgcaata acccacataa tttaaccaaa atatttttta aatgataaaa
    27781 tgcccgtcaa taccgattaa cgggcatttt acaaaaatca gttggttgat tttaaacaaa
    27841 tattttttac gacaaaaaat atttccgccc attttgccaa caaaacccaa accggaggcg
    27901 gacagatacg ctcccatccg gacgcttaat acccccataa ccatgcagct gatcgactat
    27961 tcacattcat ttttctcggt tgtgccaccc tttttggcac tggcacttgc cgtcattacc
    28021 cgccgcgtac tgctgtcttt aggcatcggt attctggtcg gcgttgcctt tttggtcggc
    28081 ggcaaccccg tcgacggtct gacacacctg aaagacatgg tcgtcggctt ggcttggtca
    28141 gacggcgatt ggtcgctggg caaaccaaaa atcttggttt tcctgatact tttgggtatt
    28201 tttacttccc tgctgaccta ctccggcagc aatcaggcgt ttgccgactg ggcaaaacgg
    28261 cacattaaaa accggcgcgg cgcgaaaatg ctgaccgcct gcctcgtgtt tgtaaccttt
    28321 atcgacgact atttccacag tctcgccgtc ggtgcgattg cccgccccgt taccgacaag
    28381 tttaaagttt cccgcgccaa actcgcctac atcctcgact ccactgccgc gcctatgtgc
    28441 gtgctgatgc ccgtttcaag ctggggcgcg tcgattatcg ccacgcttgc cggactgctc
    28501 gttacctaca aaatcaccga atacacgccg atggggacgt ttgtcgccat gagcctgatg
    28561 aactattacg cactgtttgc cctgattatg gtgttcgtcg tcgcatggtt ttccttcgac
    28621 atcggctcga tggcacgttt cgaacaagcc gcgttgaacg aagcccacga tgaaactacc
    28681 gtttcagacg ctaccaaagg tcgtgtttac gcactgatta ttcccgtttt ggccttaatc
    28741 gcctcaacgg tttccgccat gatctacacc ggcgcgcagg caagcgaaac cttcagcatt
    28801 ttgggggcat ttgaaaatac cgacgtaaac acttcgctgg tattcggcgg cacttgcggc
    28861 gtccttgccg tcgttctctg cacgctcggc acgattaaaa ccgccgacta tcccaaagcc
    28921 gtttggcagg gtgcgaaatc tatgttcggc gcaatcgcca ttttaatcct cgcttggctc
    28981 atcagtacgg ttgtcggcga aatgcacacc ggcgattacc tctccacgct ggttgcgggc
    29041 aacatccatc ccggcttcct gcccgtcatc ctcttcctgc tcgccagcgt gatggcgttt
    29101 gccacaggca caagctgggg gacgttcggc attatgctgc cgattgccgc cgccatggcg
    29161 gtcaaagtcg aacccgcgct gattatcccg tgtatgtccg cagtaatggc gggggcggta
    29221 tgcggcgacc actgctcgcc catttccgac acgaccatcc tgtcgtccac cggagcgcgc
    29281 tgcaaccaca tcgaccacgt tacctcgcaa ctgccttacg ccttaaccgt tgccgccgcc
    29341 gccgcatcgg gctacctcgc attgggtctg acaaaatccg cgctgttggg ttttggcacg
    29401 acaggcattg tattggcggt gctgattttt ctgttgaaag ataaaaaacg cgccaacgcc
    29461 tgaccccttt ccctgttcag acggcatatg ccgtctgaag ctttttggag caaaccgcaa
    29521 tgaccgtccc ccatattccg cgcggccccg tcatggcaga cattgccgcc ttccgcctga
    29581 ccggagaaga aaaacaacgc ctgctcgatc ccgccgtagg cggcatcatc ctcttccgcc
    29641 gcaacttcca aaacatcgaa cagctcaaaa cactcaccgc cgaaatcaaa gccctccgca
    29701 cacccgaact catcatcgcc gtcgatcacg agggcggaag ggtgcaacgt ttcatcgaag
    29761 gcttcacccg cctgcccgca atgagtacgc tcggcgagat ttgggacaaa gacggcgcgt
    29821 ccgccgccga aaccgccgcc ggacaagtcg gccgggtttt ggcaaccgag ctttccgcct
    29881 gcggcatcga cttgtccttc acgcccgtct tagatttgga ctggggaaac tgccccgtca
    29941 tcggcaaccg cagtttccac agtaaccccg aagccgtaac ccgcctcgcc ctcgcccttc
    30001 aaaaaggttt ggcaaaaggc ggtatgaaat cctgcggcaa acattttccc ggacacgggt
    30061 ttgtcgaagg ggacagccat ttggtgctac ccgaagacgg gcgcagcctc gacgaactcg
    30121 aagccgccga cctcattcct ttccgcatta tgagccgcga aggtatggcg gcggttatgc
    30181 ccgcccacgt cgtttatcca caagtggaca caaagcccgc cgggttttcc gaaatctggc
    30241 tgaaacagat tttgcgccgc gacatcgggt tcaaaggcgt gattttctcg gacgatttga
    30301 ctatggaggg cgcgtgcggg gcaggcggca tcaaagaacg cgcccgcatt tcctttgagg
    30361 caggttgcga cattgtcctc gtctgcaacc gtcccgacct tgtggacgaa ctgcgcgatg
    30421 atttccgcat tcccgacaat cccgctttgg cgcaacgttg gcaatacatg gccaacacgc
    30481 tcggcagcgc cgccgcgcaa gccgttatgc agacggcgga tttccaagcg gcgcaagcct
    30541 ttgttgccgc ccttgcctcg ccgcaggata cagcgggcgg cgtaaaagtc ggcgaagcct
    30601 tttaaatccg cccgacacgc ggcaaaaagg caaaacggta taggcacgcc gtattttttg
    30661 cgctataatc acgccttact taattcggaa tgtagcgcag cccggtagcg cacttcgttc
    30721 gggacgaagg ggtcggaggt tcgaatcctc tcattccgac caaatccaaa ccgcctcggc
    30781 atccattgcc ggagcggttt ttccttttgg cgtcaacaga aaaatgccgt ctgaaacagc
    30841 attctgtttc agacggcatt tcgttttccc taacccttct atttgcgtgc actgacaaag
    30901 ggtatcggca aggttcaaaa gaccatcgga atttaggaag ccgggcttgt acccaacggc
    30961 agcatcttat tcagtaaggc tccgtcctga ttgggcggtg gaaataccgg catttccacg
    31021 cagaagcggc acactttccc cgtatgtcaa acatcggtaa aacggtacgc cggccctttg
    31081 agttacactg cttaaactac tctattcccg cccatttgtg cgtctgcacg ctcaactgcc
    31141 aatgcacgga tgcgtcgggg cgactgttta aaataccgat ttggcggatg gtgtcgtaga
    31201 tgttcatcgc accgtcttgc tcacagggcg aaaggtagta atgatgtgcg cggattttgc
    31261 gttccatgtt ttcgcagaac gcaaggacat caccatcggc aacaatccgc acttcgtcgg
    31321 ctgtttcgat acagctattt tcatatttgg cggcgtagca ggctttgggg ctggtggcga
    31381 cgtagtcgat ttgcggcggc gcgggattga gtccgttggt ttcgagacag aggaaatagc
    31441 cttccgcctt gagcgtgtcc agcagcatat cgagatgcgg ctgtatggtc ggttcgccgc
    31501 cggtgatgat gatgttgcgg gcggcatagg ttttcagaca gcctaagatg tcggacaggc
    31561 tcatcatgcc gaatgtcaaa taatcggtat cacaccagcc gcaggcgagg ttgcatttgc
    31621 ccaagcggac gaaaacggcg ggcatgcccg tgttccagcc ttcgccttgc aggctttcaa
    31681 agatttcgac gatgcggtat tggggatttt cgggggcaac attgattttt ttcataccgc
    31741 caacaccgcc gccgctgcca aaaatgcggg caaaccttgt ttgacgagta tgcctttgtt
    31801 gccggaagag aacgcgcccc acgcggcggc aatcaggacg aagccgagaa acagtaccgt
    31861 cacgccgtac accgcgttat ccggcgcagc aaaccgcgac cacaccagcc cgatgccgag
    31921 aaagccgtta tacagccctt ggttgccgaa cagggtctgc acgcgatttt gttccataaa
    31981 ttcataaggc agcttgaacg tttccgccgc tttttcgctg ggaatctgtg tcatttcaag
    32041 ccaggcgatg tagaaatgtt cgacggcgac gaagaggact aggaggatga agaggagttt
    32101 catgggtaag caccttaatt tgcactaaga tttatattta acaaacttta ccaattttat
    32161 ttaacaaaaa agccacccat tatggatggc ttctctacca aaacttttca tgctactttt
    32221 ttcatggttg cagcttttgc tttataagct cgtttttcaa tttgtctttg aatagctgca
    32281 agttgcttcg ttaatgcagc aatgcgagcg aaacggatat ccattgattt cataaataac
    32341 tccttgctgt tgttaataaa ggctcgactg attatttttg agcatagaac gattccgaga
    32401 acattcctca gtatctttat ttctaacgtt agtaatcata gattgtgcgt agagaagtcc
    32461 ttgagccaaa ctaatttttt tgttttccaa agaaaaatca ttgggactga tcggaagttt
    32521 atcaacctct tgttgtaaat ttttcacaat ggattccaaa gtatccaaat caggatcaac
    32581 taaatcatgc ataccatcaa tcccaaaatc atcgtacagt ttcaaaagaa attgtacgaa
    32641 cttattaatt acatctatgc tctcggcaat aatgccttcc tcttgaatca tactactagt
    32701 tgtattcatg gttattatgc ctgaaatttt ctattacggt cgatttttta gaaagtatgg
    32761 aattttacaa ttgattatat gacaagtcaa aacaaatctt taaaatttgt ttcaatatta
    32821 ctccccttca tactccgcac acgatgtcgg cgtttcccac aatttgacgc ggcacacgtt
    32881 cagccccgcg tttttcagac ggtcgtacat ttcgaccgcc atattttcgg cagtggtgcg
    32941 gcagggcagg cgcagggttt tcatgttcca gccctccaaa agcgcggcga tttggcattc
    33001 gcggctgttg ccgccgtggt agatgaaggc gtggtcgaag gggtcggtaa tgtgttgttt
    33061 gacaatggct ttcaagtcgg taaagtccat caccataccg tctttcgcgc cgcctttgat
    33121 aatgccgtct gaaacggtga tttcgagttt gtaggtatgt ccgtgcaggt tttggcattt
    33181 gccgtcatgc ccgtcgagca tatgcgagga gtcgaaggtg aagattttgg tgattttcat
    33241 gggttctcaa atgggcaaat agccttgaaa gccgatttcg gcgggtttgc cgtgcggatt
    33301 cggggtcagg cggatatgga aattgccgat gcggtcgagc gcaagcaggt tgtccacgtc
    33361 ttttaagttg tctttatgct gctgaacata gctgtcggtc aacagggttt gcagggcttt
    33421 ttgtttggct tcggcaggcg tggcggcggc gaacagcccg aaagcgtgtg cctcggcaag
    33481 ctgacccgcg cgataaccgc cgacattggc gaaatacagg cgcggggcgt gttcagacgg
    33541 cattttcgtt ttgggcgttt cggatacggc gatgtcgtaa ccgtccgccc attcgacaat
    33601 ctgccagccg tcgatgtgga ttttgtccgc atcgccgaac cacgcggctt tgagcgcggg
    33661 gacggcctcg cggtagtcgt cgcacacggc aaattggatg tcgtgcactt cgatattcga
    33721 cctgccggca ttgccgccga ggtaaaacat atggagcttg ggcatatcgt attccttatg
    33781 gtttgcgcgt gttcagacgg cctttttact ttccagatat tccgccagcc cgcgttcgcg
    33841 caagatacag ctcgggcatt cgcggcagcc gccgacgatg ccgttatagc aggtgtgggt
    33901 ttgctcgcgg atatagtcca gcacgcccat ttcgtccgcc aacgcccaag tttgcgcctt
    33961 ggtcagatac atcagcggcg tgtggatttg aaaatcatag tccatcgcca aattaagggt
    34021 aacgttcatc gatttgacaa acacgtcgcg gcagtcagga tagccggaga agtcggtttc
    34081 gcacacgccc gcgatgatgt gccgtatccc ctgccctttg gcgtaaatcg cggcatagag
    34141 caggaaaagc gcgttgcggc cgtctacaaa ggtattcgga acgccgtttt cggcagtttc
    34201 gatggcggcg gtgtcgtcca tcagggcatt gtgcgtaatc tgccgcatca ggctcaagtc
    34261 gagtacggtt tgtttgacgc ccaaatcctg cgcaatccag ctggcacgtt ccagctcgac
    34321 ggcatggcgt tgcccgtatt ggaaagtaat ggcttggacg ttttcgcgcc cgtagatttg
    34381 gattgcctga atcaggcagg tggtcgaatc ctgaccgccc gaaaagatga ccaaggcttt
    34441 ttggtttgac atatcgaatc ctagttttgg taacgcggga ggtttgcgaa ccgcgaagtt
    34501 ggacagtaaa gacgcggatt atacaggcaa acgcgttcag acggcatctg aacgccatgc
    34561 cgtctgaaca cgcggcttat gccgacttga cggcgagttc cgccaagcgt ttgctttgtg
    34621 cgaaggcgat attgttttct tcggcggtca ggacgggagc cgctgtcggg aatatctttt
    34681 ttgacggctt cgcagacggc ggagactttg gggacggtgc gcaatacggc ttcgcaacct
    34741 tcaacgctgt cgatgccgcg agcgattcgg agtgcgggat tgcgggtgct gccgttttgg
    34801 aaatagtaga ggacgaggat tttgaggggg atttgggttc atgggcggat tccgttaaaa
    34861 tggttcggtc ttcagacggc ataacagttg ttccgatgcc gtctgaaaca gccgcagttc
    34921 aggcatttgt tcctgacggc aaaattggct ataacatcgg gcatcaatgc ccaacttact
    34981 gaccgggcaa gaaattatga cctttttaca acgtttgcaa ggtttggcag acaataaaat
    35041 ctgtgcgttt gcatggttcg tcgtccgccg ctttgatgaa gaacgcgtac cgcaggcggc
    35101 ggcaagcatg acgtttacga cgctgctggc actcgtcccc gtgctgaccg tgatggtggc
    35161 ggtcgcttcg attttccccg tgttcgaccg ctggtcggat tcgttcgtct ccttcgtcaa
    35221 ccaaaccatt gtgccgcagg gcgcggacat ggtgttcgac tatatcaatg cgttccgcga
    35281 gcaggcgaac cggctgacgg caatcggcag cgtgatgctg gtcgttacct cgctgatgct
    35341 gattcggacg atagacaata cgttcaaccg catctggcgg gtcaattccc agcgtccgtg
    35401 gatgatgcag tttctcgtct attgggcttt actgacgttc gggccgctgt ctttgggcgt
    35461 gggcatttcc tttatggtcg gctcggtaca ggatgccgcg cttgcctcag gtgcgccgca
    35521 gtggtcgggc gcgttgcgaa cggcggcgac gctgaccttc atgacgcttt tgctgtgggg
    35581 gctgtaccgc ttcgtgccaa accgcttcgt tcccgcgcgg caggcgtttg tcggggcttt
    35641 ggcaacagcg ttttgtctgg aaaccgcgcg ctccctcttc acttggtata tgggcaattt
    35701 cgacggctac cgctcgattt acggcgcgtt tgccgccgtg ccgttttttc tgttgtggct
    35761 gaacctgttg tggacgctgg tcttgggcgg cgcggtgctg acttcttcac tctcctactg
    35821 gcagggagaa gcgttccgca ggggcttcga ttcgcgcgga cggtttgacg acgtgttgaa
    35881 aatcctgctg cttctggatg cggcgcaaaa agaaggcaaa gccttgcctg ttcaggagtt
    35941 cagacggcat atcaatatgg gctacgacga gttgggcgag cttttggaaa agctggcgcg
    36001 gtacggctat atctattccg gcagacaggg ttgggtgttg aaaacggggg cggattcgat
    36061 tgagttgaac gaactcttca agctcttcgt ttaccgtccg ttgcctgtgg aaagggatca
    36121 tgtgaaccaa gctgtcgatg cagtaatgat gccgtgtttg cagactttga acatgacgct
    36181 ggcagagttt gacgctcagg cgaaaaaaca gcagcaatct tgagtatttt tgaaactgta
    36241 tttttatcct aaagacattt tcctatctgc tgattccacc gtttcctttc tgtgtgccgc
    36301 cataattttt atgatagaca agccattcaa gtttgcattg actgcttttt cattggcaat
    36361 atccaaatgg ctggtcgctg catctaaaaa taggattttc ggttcgcaat ataaggcccg
    36421 cgccaatacg atgcgttgtt tttgtccgcc tgacagtgcg ctgcccatat cgccgatcaa
    36481 ggtttcatag cccataggca tggcggagat ttcttcgtga atcatagcaa ggcaggcgca
    36541 atgttcgatt tttcctctat ccggttccgt atcgaaaaaa caaggggctg tactagatta
    36601 gccctaaatc ccacaccaat cccgcaggat tttaagctgt tgagacggtg tgccgaagtt
    36661 aaatcgaaat tcgcattctt tcaagaacag cgggaaagat ttacgatcga ttccgttgta
    36721 ttttcgcaag acgcgtttag tctagagtct gtatattaca tttattttta gggtctgcta
    36781 gccaatttct tgttcccttc attattttat cttctgaaag aaaattattt ttttccatgc
    36841 tattaatatt aatgatatga tttttattta aaataatttt tccatataaa atttccggtt
    36901 tgtaatagca agagtctgaa gcaaatcctt gcccgtcaat ataagaaaaa taaatgttat
    36961 catcctcctt ataatattct aaaaccaatc cggatattat tttatcaaaa ttcccttcat
    37021 ttccatcttt catgactaaa atataattag caggccaacc tttatcgtaa acatattcaa
    37081 actgatagtt cccgaaactc tcgatatccg aactaaaaaa gaagaaaagc aaattaatag
    37141 ccaatacaaa aacaaataag aacaaaaata gcaaaatttt caacttagtt aacaatattt
    37201 acctctcctt taaattcaat cctgaaaggt accccttacc ctgggctacc aattatagtt
    37261 tccatatttc taaatattgt ttttacatta cttttttctc cccccaaagg aatgcatttt
    37321 aaaatcatgc ttttcaggtg ctaatcgata cttaccatta acatctttaa tcacagatat
    37381 atttccatgt atagcccaac gtgaaaaatc tgagtattat atacagttat accttactga
    37441 aacaaagcta gctgtacata tctgtaccat atttttacta caaacaaaaa atatttataa
    37501 ttattaagga taagataaaa acccccaacg ctagattaat tcttaataat ttcaaataaa
    37561 aaatatttga gattttttct tttccaaata atatattgaa atatttaaag ttaaggtagc
    37621 ttgatttaag tagaaaatca aaaaaaccat taattaattt ttcttcttta aatattttat
    37681 atgatattat aaaattaaat aacattgcga aaacatatga aatcatcaaa ataccaaata
    37741 tatagtggga atgcattatt atttagctcc ttcttttggc tctgacaaat tgacagtcca
    37801 ttgatatcca atgcttgcat ttgcaattgc tgacgcacct gcccctgttt tccctgttag
    37861 tatcaatggt tcttttcttg caagatgtgc acctgcacaa ccacctaata ctaaaccacc
    37921 acctattgta aatccttcct gttgtatctc taatgataac attttcttct tgtgccgccc
    37981 ttaatacaga ttgtggaatt ggattgacct gagcaggaac ttctaaaata agttttcctt
    38041 caagctgtct tcctcttagc gaagcaggtg tacttggaac attggaaatg acaaagtgag
    38101 tgcgcaaagc cacctgaagg cgatgtgttt gaa
//
LOCUS       DAXISH010000012        37429 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.012, whole genome shotgun sequence.
ACCESSION   DAXISH010000012 DAXISH010000000
VERSION     DAXISH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 37429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37429
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.012"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..696
                     /locus_tag="ACFOV4_000631"
     CDS             <1..696
                     /locus_tag="ACFOV4_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFC7618701.1"
                     /translation="NNSITGIASFSFSQLIMNKEAIKYDPRQIRELVKFISQFSFLSW
                     YENKLFLDITDFSELHLLENQFIADTQPQERLDSLEIMRLGKTNNNFLLMNEIVSLSI
                     DDQAFSEGGKIKVTHLITERNSILRKIYFSKTQNAQICRMCGLDTQRSYEWSEHIIEV
                     HHLLPLSSPVRVEDKTTSLKDLVGICPTCHRATHKYYTFWLNLHKKKDFVSYEEAYHV
                     YEEAKSKVKRIYK"
     gene            709..1911
                     /locus_tag="ACFOV4_000632"
     CDS             709..1911
                     /locus_tag="ACFOV4_000632"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFC7618702.1"
                     /translation="MLIPQTSLFDQENNRIISQRKLLEQSLLQGIPLNELIRQNQMSY
                     DDLIYIHHDKKPFEKRKNLVLSDFQKKENHIPIISFFSGAGGLDLGFEAAGFQHSMLI
                     EKIPLFCDTLRLNRPNWSVFNADVSETEEMVELIRNNIGSLSFDGVFIGGPPCQPFSI
                     ASNQRFSKTDKNFKRVGFEHKQNGNLLFNYVELIKIFRPKVFLIENVSGLMDIDNGKQ
                     LASVYCDLQQQGYSLYKPQIINSEYFHVPQQRIRLFIIGYLGDKKFSPLQPTNTPLAC
                     GNTFEIPIINQHNHITREHSAESILRYMELAYGQRDKKGRVDRLDPSKPSKTIIAGGT
                     KGGGRSHLHPYIPRTLSVRESARLQTFPDDYIFTGAVARQFTQVGNAVPPILAAQLAT
                     AIKHSYFE"
     gene            2197..2340
                     /locus_tag="ACFOV4_000633"
     CDS             2197..2340
                     /locus_tag="ACFOV4_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618703.1"
                     /translation="MARYRRNFIAGGTFFFTVKLADPKSRLLVEHIGFAYGLYGCAKT
                     ISL"
     gene            2312..2635
                     /locus_tag="ACFOV4_000634"
                     /pseudo
     CDS             2312..2635
                     /locus_tag="ACFOV4_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258178.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2875..3765)
                     /gene="sucD"
                     /locus_tag="ACFOV4_000635"
     CDS             complement(2875..3765)
                     /gene="sucD"
                     /locus_tag="ACFOV4_000635"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016655272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HFC7618704.1"
                     /translation="MSVLINKDTKVLVQGFTGKNGTFHSEQALAYGTKVVGGVTPGKG
                     GQTHLNLPVFNTMKEAVKETGADASVIYVPAPFVLDSIVEAVDSGVGLVVVITEGVPT
                     LDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHTPGRIGIISRSGTLT
                     YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQEDPDTDAIIMIGEIGGTAEE
                     EAAEYIQSNVTKPVVGYIAGVTAPKGKRMGHAGAIISGGKGTAEEKFAAFEKAGIAYT
                     RSPAELGTTMLEVLKAKGLA"
     gene            complement(3776..4987)
                     /gene="sucC"
                     /locus_tag="ACFOV4_000636"
     CDS             complement(3776..4987)
                     /gene="sucC"
                     /locus_tag="ACFOV4_000636"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HFC7618705.1"
                     /translation="MEANSGHYTNLKEKSMNLHEYQAKELLAGYGLPVQGGILAHNGE
                     EAAAAYDKLGGKFAVVKAQVHAGGRGKAGGVKVVKSREEAKEVAESLIGTNLVTYQTD
                     ANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTRRVTFMASTEGGVEIEKVAAETPEKI
                     FKVTVDPLVGLQPCQAREVAFQLGLKDKQINEFVKLMTGAYKAFVENDFALFEVNPLA
                     VRENGALACVDGKIGIDSNALYRLPKIAELRDKSQENERELKASEFDLNYVALEGNIG
                     CMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVVEAFKLILEDKSVQGVLINI
                     FGGIVRCDMIAEAIVAAVKEINVDVPVVVRLEGNNAELGAKILNESGLKLTSADGLND
                     AAEKIVAAVNA"
     gene            complement(5041..5328)
                     /locus_tag="ACFOV4_000637"
     CDS             complement(5041..5328)
                     /locus_tag="ACFOV4_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618706.1"
                     /translation="MNKEIVGIFFIPMGIISMCMAALWQMYVMMTETYTLNRFKDKEL
                     VWRVALLFISFSLAVYLLCPNSRKKGIVFFILGGGGAAMYLLARMWLPFSK"
     gene            complement(5423..6856)
                     /gene="lpdA"
                     /locus_tag="ACFOV4_000638"
     CDS             complement(5423..6856)
                     /gene="lpdA"
                     /locus_tag="ACFOV4_000638"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003745605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFC7618707.1"
                     /translation="MSQYDVVVIGAGPGGYVAAIRAAQLGFKTACVDAGVNKAGNAPA
                     LGGTCLNVGCIPSKALLQSSEHFHAAQHEFAEHGITVGDVKFDVAKMIERKDAIVTKL
                     TGGVKFLFQKNKVTSLFGTASFAGKNGDAYQIEVDNKGEKTVIEAKHVIVATGSVPRP
                     LPQVAIDNVNVLDNEGALNLTEVPAKLGVIGSGVIGLEMGSVWNRVGAEVTILEAAPT
                     FLAAADQQIAKEAFKYFTKEQGLSIELGVKIGDIKSEGKGVSVAYETAAGEAKTEVFD
                     KLIVAIGRIPNTKGLNAEAVGLEKDERGFIKVDGECRTNLPNVWAIGDVVRGPMLAHK
                     ASDEGVAVAERIAGQKPHIDFNNVPFVIYTDPEIAWVGKTEEQLKAEGVEYKKGTSGF
                     GANGRALAMGKAKGTVKVLADAKTDRILGVHMIGPVVSELLTEGVTALEFFASSEDIA
                     RIIHAHPTLSEVVHEAALAADKRALHG"
     gene            7053..7169
                     /locus_tag="ACFOV4_000639"
                     /pseudo
     CDS             7053..7169
                     /locus_tag="ACFOV4_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(7221..8402)
                     /gene="odhB"
                     /locus_tag="ACFOV4_000640"
     CDS             complement(7221..8402)
                     /gene="odhB"
                     /locus_tag="ACFOV4_000640"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA];
                     GO_function: GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HFC7618708.1"
                     /translation="MIIDVKVPMLSESVSEGTLLEWKKKVGEAVARDEILIDIETDKV
                     VLEVPSPQAGVLVEIVAQDGETVVADQVLARIDTAATAAAEAPAAAPAEAAPAAAPAA
                     AQNNAAMPAAAKLAAESGVDVNALQGSGRDGRVLKEDVQNAAAKPAAAAAPAVALPAG
                     ARPEERVPMSRLRARVAERLLASQQENAILTTFNEVNMKPIMDLRAKYKEKFEKEHGV
                     KLGFMSFFVKAAVAALKKYPVVNASVDGKDIVYHGYFDIGIAIGSPRGLVVPILRDAD
                     QMSIADIEQAIVDYAKKAKDGKIAIEDLTGGTFSITNGGTFGSMMSTPIINPPQSAIL
                     GMHATKERAVVENGQVVVRPMMYLALSYDHRIIDGREAVLTLVAIKDALEDPARLLLD
                     L"
     gene            complement(8502..11330)
                     /locus_tag="ACFOV4_000641"
     CDS             complement(8502..11330)
                     /locus_tag="ACFOV4_000641"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HFC7618709.1"
                     /translation="MMDEKLNFSYLFGSNAPYIEELYEAFLENPDTVDEKWKQYFTDL
                     SKQPGTVAVDVAHTPIRESFVTLAKKKIASAVAGGADEAMLKKQVSVLRLISAYRIQG
                     VGAAQLDPLKRIPPRDIEALDPKFHGLSDADMALQFNMGEGDFANRGKLPLSQIISNL
                     KQTYCGHIALEYIYIPNTEERRWVRNYFESVLSTPHYNADQKRRILKEMTAAETLERY
                     LHTKYVGQKRFGVEGGESAIAGLNYLIQNAGKDGVEEVIIGMAHRGRLNVLVNILGKK
                     PGDLFAEFEGRAEIKLPSGDVKYHMGFSSDIATPHGPMHVSLAFNPSHLEIVNPVVEG
                     SARAKQKRLGENGRDKVLPVLIHGDSAFIGLGVNQATFNLSKTRGYTTGGTVHIVINN
                     QIGFTTSDIRDTRSTVHCTDIAKMVSAPVIHVNGDDPERVCFAIQAALDYRKKFHKDI
                     VIDVVCYRKWGHNEGDDPTLTQPMMYKKVSQHPGARALYTEQLIAEGVVTQAEADGYI
                     QAYRDALDKGEHVEQTTLSNFQRTQIDWSKYQGKDWREHIETGLPAADIERLTEKFTA
                     VPEGFALHPTAKRVIEARKAMASGKQAIDWGMAETLAYASLVTKGHGVRISGEDSGRG
                     TFSHRHAVLHDQKREKWDDGTYVPLRHMGEGMGEFLVIDSILNEEAVMAFEYGFACSA
                     PDKLTIWEAQFGDFANGAQVTIDQFLSSGETKWGRLCGLTTILPHGYDGQGPEHSSAR
                     VERWLQLCSENNMQVIMPSEASQMFHLLQRQVLGSYRKPLVIFMSKRLLRFKGAMSPL
                     ENFTEGSTFRPVVGDTAERASNDSVKRVVLCAGQVYYDLEAGRAERKLEDDVAIVRVE
                     QLYPFPYDEVKAELAKYPNAKSVVWAQEEPKNQGAFYQIRHRIEDVISEEQKLSYAGR
                     PSSASPAVGYSSKHIAQLKQLVEDALAL"
     gene            complement(11535..12818)
                     /gene="gltA"
                     /locus_tag="ACFOV4_000642"
     CDS             complement(11535..12818)
                     /gene="gltA"
                     /locus_tag="ACFOV4_000642"
                     /EC_number="2.3.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004108 - citrate (Si)-synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HFC7618710.1"
                     /translation="MSKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFD
                     PGFVSTASCESKITYIDGDQGLLYYRGYPIEQLAEKSDYLEVCYLLIYGELPTPEQKA
                     EFDNTVRRHTMVHEQLTWFFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKI
                     AIYRLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLAR
                     ALDRIFILHADHEQNASTSTVRLAGSSGANPFACIAAGIACLWGASHGGANEAVLKML
                     DEIGDVSNVAAYMEGVKQRKYRLMGFGHRVYRNMDPRASIMRETCYEVLKELGLEDSP
                     KFKLAMELEQIALKDPFFIERKLYPNVDFYSGIVLSALGIPTEMFTVIFALSRSVGWI
                     SHWHEMISDPSLKIGRPRQLYTGSERRDYVPPGER"
     gene            complement(12930..13178)
                     /locus_tag="ACFOV4_000643"
     CDS             complement(12930..13178)
                     /locus_tag="ACFOV4_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase assembly factor 2"
                     /protein_id="HFC7618711.1"
                     /translation="MMVFDDIAKRKIRFQTRRGLLELDLIFGRFMEKEFEHLSDKELS
                     EFSEILEFQDQELLALINGHSETDKGHLIPMLEKIRRA"
     gene            complement(13182..13889)
                     /locus_tag="ACFOV4_000644"
     CDS             complement(13182..13889)
                     /locus_tag="ACFOV4_000644"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008177 - succinate dehydrogenase
                     (quinone) activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit"
                     /protein_id="HFC7618712.1"
                     /translation="MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKA
                     QDDTLSFRRSCREGICGSDGMNINGKNGLACLTDLRGLKQPVKIRPLPGLPVIRDLIV
                     DMTQFFKQYHSVKPYVVNDNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFW
                     WNPDKFVGPSGLLNAYRFIADSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLN
                     PTRAIGKIKEIMLKRAV"
     gene            complement(14010..15773)
                     /gene="sdhA"
                     /locus_tag="ACFOV4_000645"
     CDS             complement(14010..15773)
                     /gene="sdhA"
                     /locus_tag="ACFOV4_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HFC7618713.1"
                     /translation="MGFPVRKFDAVIVGGGGAGLRAALQLSKSGLNCAVLSKVFPTRS
                     HTVAAQGGISASLGNVQEDRWDWHMYDTVKGSDWLGDQDAIEFMCRAAPEAVIELEHM
                     GMPFDRVESGKIYQRPFGGHTAEHGKRAVERACAVADRTGHAMLHTLYQQNVRANTQF
                     FVEWTAQDLIRDENGDVVGVTAMEMETGEVYIFHAKAVMFATGGGGRIYASSTNAYMN
                     TGDGLGICARAGIPLEDMEFWQFHPTGVAGAGVLITEGVRGEGGILLNADGERFMERY
                     APTVKDLASRDVVSRAMAMEIYEGRGCGKNKDHVLLKIDHIGAEKIMEKLPGIREISI
                     QFAGIDPIKDPIPVVPTTHYMMGGIPTNYHGEVVVPQGDEYEVPVKGLYAAGECACAS
                     VHGANRLGTNSLLDLVVFGKAAGDSMIKFIKEQSDWKPLPADAGELTRQRIERLDNQT
                     DGENVDALRRELQRSVQLHAGVFRTDEILSKGVREVMAIAERVKRTEIKDKSKVWNTA
                     RIEALELDNLIEVAKATLVSAEARKESRGAHASDDHPERDDENWMKHTLYHSDTNTLS
                     YKPVHTKPLSVEYIKPAKRVY"
     gene            complement(15776..16117)
                     /gene="sdhD"
                     /locus_tag="ACFOV4_000646"
     CDS             complement(15776..16117)
                     /gene="sdhD"
                     /locus_tag="ACFOV4_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0045273 - respiratory chain complex II
                     (succinate dehydrogenase) [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, hydrophobic membrane
                     anchor protein"
                     /protein_id="HFC7618714.1"
                     /translation="MVERKLTGAHYGLRDWAMQRATAVIMLIYTVALLVVLFSLPKEY
                     SAWQAFFSQTWVKVFTQVSFIAVFLHAWVGIRDLWMDYIKPFGVRLFLQVATIVWLVG
                     CLVYSIKVIWG"
     gene            complement(16111..16488)
                     /gene="sdhC"
                     /locus_tag="ACFOV4_000647"
     CDS             complement(16111..16488)
                     /gene="sdhC"
                     /locus_tag="ACFOV4_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045273 - respiratory chain complex II
                     (succinate dehydrogenase) [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, cytochrome b556
                     subunit"
                     /protein_id="HFC7618715.1"
                     /translation="MSAKPRPVYLDLPNIRLPIPGIVSILHRISGVGLFIMLPFLLYF
                     LSGTLSQESAFETYRAIVSHPLVKLVLIGVLWAYLHHSLAGIRFLFLDAHKGLELNTA
                     RNTAKAVFASALVLTVVLGALLW"
     gene            complement(16767..18170)
                     /locus_tag="ACFOV4_000648"
     CDS             complement(16767..18170)
                     /locus_tag="ACFOV4_000648"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFC7618716.1"
                     /translation="MKKIQADVVVIGGGTAGMGAFRNARLHSDNVYLIENNVFGTTCA
                     RVGCMPSKLLIAAAEARHHALHTDPFGVHLDKDSIVVNGEEVMQRVKSERDRFVGFVV
                     ADVEEWPADKRIMGSAKFIDEHTVQIDEHTQITAKSFVIATGSRPVILPQWQSLGNRL
                     IINDDVFSWDTLPKRVAVFGPGVIGLELGQALHRLGVKVEIFGLGGIIGGISDPVVSD
                     EAKAVFGEELKLHLDAKTEVKLDADGNVEVHWEQDGEKGVFVAEYMLAAVGRRPNVDN
                     IGLENINIEKDARGVPVADPLTMQTSIPHIFIAGDASNQLPLLHEAADQGKIAGDNAS
                     RYPNIGGGLRRSTIGVVFTSPQIGFVGLKYAQVAAQYQADEFVIGEVSFKNQGRSRVM
                     LVNKGHMRLYAEKATGRFIGAEIVGPAAEHLAHLLAWAHQMKMTVPQMLDMPFYHPVI
                     EEGLRTALRDADAKLKA"
     gene            complement(18419..19156)
                     /locus_tag="ACFOV4_000649"
     CDS             complement(18419..19156)
                     /locus_tag="ACFOV4_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HFC7618717.1"
                     /translation="MALQDRTGQKVPSVVFRTRVGDTWKDVSTDDLFKGKKVVVFSLP
                     GAFTPTCSSSHLPRYNELFGAFKENGVDAIYCVSVNDTFVMNAWAAEEESDNIYMIPD
                     GNGEFTEGMGMLVGKEDLGFGKRSWRYSMLVNDGVVEKMFIEPEEPGDPFKVSDADTM
                     LQFVAPDWKAQESVAIFTKPGCQFCAKAKQALQDKGLSYEEIVLGKDATVTSVRAITG
                     KMTAPQVFIGGKYIGGSEDLEAYLAKN"
     gene            complement(19433..21709)
                     /gene="metE"
                     /locus_tag="ACFOV4_000650"
     CDS             complement(19433..21709)
                     /gene="metE"
                     /locus_tag="ACFOV4_000650"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFC7618718.1"
                     /translation="MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLRE
                     KNWKHQAAANADYVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGN
                     KDQFAIEMTKWFDTNYHYLVPEFHADTEFKANAKHYVQQLKEAQALGLKAKPTVVGPL
                     TFLWVGKEKGEVAFDRLSLLPKLLPVYVEILTALVEAGAEWIQIDEPALTVDLPKEWV
                     EAYKDVYATLSKVSAKILLSTYFGSVAEHAALLKSLPVDGLHIDLVRAPEQLDAFADY
                     DKVLSAGIIDGRNIWRANLNKVLETVEPLQAKLGDRLWISSSCSLLHTPFDLSVEEKL
                     KANKPDLYSWLAFTLQKTQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRA
                     DVAKRLADLPANADQRKSPFADRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARSAFK
                     KGELSAADYEAAMKKEIALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQY
                     GWVQSYGSRCVKPPIIFGDVSRPEAMTVAWSTYAQSLTKRPMKGMLTGPVTILQWSFV
                     RNDIPRSTVCKQIALALNDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAG
                     ESFRLSSAGCEDSTQIHTHMCYSEFNDILPAIAAMDADVITIETSRSDMELLTAFGEF
                     KYPNDIGPGVYDIHSPRVPTEAEVEHLLRKAIEVVPVERLWVNPDCGLKTRGWKETLE
                     QLQVMMNVTHKLRAELAK"
     gene            complement(21844..22722)
                     /gene="metF"
                     /locus_tag="ACFOV4_000651"
     CDS             complement(21844..22722)
                     /gene="metF"
                     /locus_tag="ACFOV4_000651"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HFC7618719.1"
                     /translation="MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIH
                     RLQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAK
                     DYWDSGIRRIVALRGDEPPGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSA
                     QADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQL
                     GKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLN
                     RSELTYAICHILGVRP"
     gene            22922..23197
                     /locus_tag="ACFOV4_000652"
     CDS             22922..23197
                     /locus_tag="ACFOV4_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFC7618720.1"
                     /translation="MKPNIHPDNYRTVLFFDSSANEGWLIRSCAETHGKTMVWTDGKE
                     YPLFSLDTSSASHPVYTGKQRNVNTEGRASKFNQRFQSVMSSFRKDK"
     gene            23197..23322
                     /gene="ykgO"
                     /locus_tag="ACFOV4_000653"
     CDS             23197..23322
                     /gene="ykgO"
                     /locus_tag="ACFOV4_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HFC7618721.1"
                     /translation="MQVLSSLKTAKQRHRDCQIVRRRGKVYVICKSNPRFKARQR"
     gene            complement(23584..23784)
                     /locus_tag="ACFOV4_000654"
     CDS             complement(23584..23784)
                     /locus_tag="ACFOV4_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618722.1"
                     /translation="MIGRLFRIFFFFALAALIINRLFSRRQKRALREVAEISAWVLLG
                     AAAAMLFWYLFMLYFKHIPDSY"
     gene            23934..25073
                     /locus_tag="ACFOV4_000655"
     CDS             23934..25073
                     /locus_tag="ACFOV4_000655"
                     /EC_number="2.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-acetyltransferase"
                     /protein_id="HFC7618723.1"
                     /translation="MSQNASVGIVMPQKIPFEMPLVLENGKTLPRFDLMIETYGELNA
                     EKNNAVLICHALSGNHHVAGRHSAEDKYTGWWDNMVGPGKPIDTERFFVVGLNNLGGC
                     DGSSGPLSINPETGREYGADFPVVTVKDWVKSQAALADYLGIEQWAAIVGGSLGGMQA
                     LQWTISYPERVRHALVIASAPKLSTQNIAFNDVARQAILTDPDFNEGHYRSHNTVPAR
                     GLRIARMMGHITYLAEDGLGKKFGRDLRSNGYQYGFGVEFEVESYLRYQGDKFVGRFD
                     ANTYLLMTKALDYFDPAADFGDSLTRALQNVKAKFFVASFSTDWRFAPERSHELVKAL
                     ITAQKSVQYIEVKSAHGHDAFLMEDEAYMRAVAAYMNNVYKECQQ"
     gene            25070..25651
                     /gene="metW"
                     /locus_tag="ACFOV4_000656"
     CDS             25070..25651
                     /gene="metW"
                     /locus_tag="ACFOV4_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine biosynthesis protein MetW"
                     /protein_id="HFC7618724.1"
                     /translation="MNLRDDLQLIYDRIPEGSRVLDLGCGDGELLAALVEHKKCSGYG
                     IEIDTDSVIAAMSRGVNVIQADLEEGLTAFNDQSFDVIVLSQTIQAMQNTEKILRCLM
                     RVAKQAIVSFPNFGYWRNRVQIALGGHMPVSERMPYHWYDTPNIHWCTLKDFDLLCAK
                     NNIRVLERAVMTGNRQVKHFPNLLGSLAFYRVG"
     gene            25768..26604
                     /locus_tag="ACFOV4_000657"
     CDS             25768..26604
                     /locus_tag="ACFOV4_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NMB0938 family lipoprotein"
                     /protein_id="HFC7618725.1"
                     /translation="MKNKTSSLLLWLAAIMLTACSPNKNDKTKEVGASAASSSASSAS
                     SQSDLQPAASAPDNVKQAESAPPSNCTSLHPATGIDDLMQQIAEHIDSDCLFALSHHE
                     LETRFGLPGGGYDNIQRLLFPDIRPEDPDYHQKIILAIEDLRYGKRTISRQAQDALME
                     PERRLREATLLLIQGSQETRGQGEEPKRTRYFEVSATPAYSSRHNNGLGGNFQYIGQL
                     PGYLKIHGEMLENQSLFRLSNRERNPDKPFLDIHFDENGKITRIVVYEKNIYFNPNLG
                     RR"
     gene            complement(26654..27214)
                     /gene="efp"
                     /locus_tag="ACFOV4_000658"
     CDS             complement(26654..27214)
                     /gene="efp"
                     /locus_tag="ACFOV4_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFC7618726.1"
                     /translation="MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNL
                     LTGAASETIYKADDKFDVVILSRKNCTYSYFADPMYVFMDEEFNQYEIEADNIGDALK
                     FIVDGMEDQCEVTFYEGNPISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTE
                     IQVMSYIENGDKIEIDTRTGEFRKRA"
     gene            complement(27257..28408)
                     /gene="earP"
                     /locus_tag="ACFOV4_000659"
     CDS             complement(27257..28408)
                     /gene="earP"
                     /locus_tag="ACFOV4_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0106361 - protein-arginine
                     rhamnosyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P maturation arginine
                     rhamnosyltransferase EarP"
                     /protein_id="HFC7618727.1"
                     /translation="MNTYAFPVCWIFCKVIDNFGDIGVSWRLARVLHRELGWQVHLWT
                     DDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDAVIETFACDLPENVLH
                     IIRRHKPFWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYRD
                     AVRFDTEALRQRLMLPEKNAPEWLLFGYRSDVWAKWLEMWQQAGSPMTLLLAGTQIID
                     SLKQSGVIPQNALQNDGDVFQTASVCLVKIPFVPQQDFDKLLHLADCAVIRGEDSFVR
                     AQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTSETASAHRRLSDDLNGGEALSA
                     TQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSASEKLAAFVSKHQKIR"
     gene            complement(28427..28705)
                     /locus_tag="ACFOV4_000660"
     CDS             complement(28427..28705)
                     /locus_tag="ACFOV4_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618728.1"
                     /translation="MFRNLLVRWLAVCLIPLATLAVFAANPPEDKPQHLINGIILACE
                     ATFLFKFVLFDTIKHHLKQEFDLKHQTMFLFIPIVLLVVYLFHYFGAF"
     gene            29059..30000
                     /gene="miaA"
                     /locus_tag="ACFOV4_000661"
     CDS             29059..30000
                     /gene="miaA"
                     /locus_tag="ACFOV4_000661"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFC7618729.1"
                     /translation="MPTPKAFALLGPTAGGKTALALKIAETLPVEIISLDSALVYRDM
                     DIGTAKPSASERAFVPHHLIDIIPPTESYSAARFVEDCTRLVGEISSRGRFALIVGGT
                     MMYFRALTQGLNDLPEADACLRADLDEQKQMYGLDFLYRTLQKVDPETACRLKPNDSQ
                     RIGRALEVYYLTGKPMSTHLGSLTSHTLPFDLHTAALIPENRARLHENIALRFHLMLE
                     QGFIGEVENLRRRYPSLTADSPAIRCVGYRQAWKYLDGKTDFPAFVEKGIAATRQLAK
                     RQLTWLRKTPLDCVADPFSDGTSCTRLIEAAKRFFGA"
     gene            30004..30723
                     /gene="tadA"
                     /locus_tag="ACFOV4_000662"
     CDS             30004..30723
                     /gene="tadA"
                     /locus_tag="ACFOV4_000662"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFC7618730.1"
                     /translation="MLTTPPLAPKTVAALHRLGIRTLEELRQNGSVKAFLLLKASGLT
                     LTKSTLWQLESLLDGTPPQEMSQAHKARLLAELKNHPPVAAFPPQEEMEHFMREALRQ
                     AEQSAADGEIPVGAVIVSDGKIIAAAHNTCIADCNVSRHAEINALAQAGSEMQNYRLD
                     GCDIYITLEPCAMCASALIQARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTAIRG
                     GILQEECRAVLSRFFQNKRKG"
     gene            30728..31216
                     /locus_tag="ACFOV4_000663"
     CDS             30728..31216
                     /locus_tag="ACFOV4_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF456 domain-containing protein"
                     /protein_id="HFC7618731.1"
                     /translation="MTALLVILALALIAAGTAGIVYPALPGLALMFAGTWLLAYSGGY
                     QIYGAGVLWTVGLISLAGILADYVAGIWGTKYTGAGKLAVRGALVGSIIGIFFSLPGL
                     ILGPFIGAAAGELIDRRNMLQAGKAGLGTLLGLIVGTTFKIGCAVSILFILLVKYIAY
                     LF"
     gene            31282..32034
                     /gene="rlmB"
                     /locus_tag="ACFOV4_000664"
     CDS             31282..32034
                     /gene="rlmB"
                     /locus_tag="ACFOV4_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFC7618732.1"
                     /translation="MANQRPIYGFHAVNARLWQNPKSIVELYVQEGKNDVRTREVLEK
                     AANENIRVYFADADRLNAISKGARHQGVVGFIDASKNHVHLEDVLENLSEPPLLLILD
                     GITDPHNLGACLRTADAMGVHAVIAPKDKSAGLNATVSKVASGAAETVPYITVTNLAR
                     TLRELKEYGIWIIGTDMGGNADLYHCDLPDSAAWVMGNEGDGMRRLTREHCDMLVSIP
                     MFGTVESMNVSVSAGMVLSETRRQRVLKNEKA"
     gene            complement(32096..33488)
                     /locus_tag="ACFOV4_000665"
                     /pseudo
     CDS             complement(32096..33488)
                     /locus_tag="ACFOV4_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
     gene            complement(33503..33757)
                     /locus_tag="ACFOV4_000666"
     CDS             complement(33503..33757)
                     /locus_tag="ACFOV4_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618733.1"
                     /translation="MLPIVAYFTAGVKSGGSGMHGAAWRRMRRVCIFVFEIRLLRFAN
                     DIPAATVRNLFAGRARMPSEIEIEAVWRIRYNPRFGFFNI"
     gene            33795..34670
                     /gene="dapA"
                     /locus_tag="ACFOV4_000667"
     CDS             33795..34670
                     /gene="dapA"
                     /locus_tag="ACFOV4_000667"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFC7618734.1"
                     /translation="MLQGSLVALITPMNQDGSIHYEQLRDLIDWHIENGTDGIVAVGT
                     TGESATLSVEEHTAVIEAVVKHVAKRVPVIAGTGANNTVEAIALSQAAEKAGADYTLS
                     VVPYYNKPSQEGIYRHFKAVAEAAAIPMIIYNVPGRTVVSMTNDTILRLAEIPNIVGV
                     KEASGNIGSNIELINRAPEGFVVLSGDDHTALPFMLCGGHGVITVAANAAPKLFADMC
                     RAALQGDIALARELNDRLIPIYDTMFCEPSPAAPKWAVSALGRCEPHVRLPLVPLTEG
                     GQAKVRAALKASGQL"
     gene            34679..35875
                     /gene="bamC"
                     /locus_tag="ACFOV4_000668"
     CDS             34679..35875
                     /gene="bamC"
                     /locus_tag="ACFOV4_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HFC7618735.1"
                     /translation="MPSEPFGRHNATNTLISITQDDTMTHIKPVIAALALIGLAACSG
                     SKTEQPKLDYQSRSHRLIKLEVPPDLNNPDQGSLYRLPAGSGAVRASDLEKRRTPAVQ
                     QPADAEVLKSVKGVRLERDGSQRWLVVDGKSPAEIWPLLKAFWQENGFDIKSEEPAIG
                     QMETEWAENRAKIPQDSLRRLFDTVGLGGIYSTGERDKFIVRIEQGKNGVSDIFFAHK
                     AMKEVYGGKDKDTTVWQPSPSDPNLEAAFLTRFMQYLGVDGQQAENASAKKPTLPAAN
                     EMARIEGKSLIVFGDYGRNWRRTVLALDRIGLTVVGQNTERHAFLVQKAPNESNAVTE
                     QKPGLFKRLLGKGKAEKPAEQPELIVYAEPVANGSRIVLLNKDGSAYAGKDASALLGK
                     LHSELR"
     gene            complement(35932..36864)
                     /gene="pip"
                     /locus_tag="ACFOV4_000669"
     CDS             complement(35932..36864)
                     /gene="pip"
                     /locus_tag="ACFOV4_000669"
                     /EC_number="3.4.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl aminopeptidase"
                     /protein_id="HFC7618736.1"
                     /translation="MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAG
                     ASPECRGFFNPDVFRIVIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIRKWL
                     VFGGSWGSTLSLAYAQTHPERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKF
                     VAPIAENRRNRLIEAYHGLLFHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASL
                     AIARLENHYFVNGGWLQGDRAILNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFP
                     EAELRVVQAGHRAFDPPLVDALVQAVEDILPHLL"
     gene            complement(37168..>37429)
                     /locus_tag="ACFOV4_000670"
     CDS             complement(37168..>37429)
                     /locus_tag="ACFOV4_000670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618737.1"
                     /translation="RFWIPAFAGMTKSGGNDGSVATVIVRFRLCWNFGKLMNCHSRAG
                     GNLEFQCLKNLSEKTKTLPPSFPRKWESRNEKQQEFIGNDRN"
BASE COUNT         9467 a         9911 c         9050 g         9001 t
ORIGIN      
        1 aataatagta ttacaggtat tgcttctttt tcattctcac agttaattat gaataaagaa
       61 gcaattaaat atgatcctcg tcaaattaga gagttggtaa agtttattag tcaattctct
      121 tttttgtctt ggtatgaaaa taagttgttt ttagatatta cagattttag tgaactacat
      181 ttattagaaa accaatttat tgcagataca caaccacaag aaagattaga tagtttagag
      241 ataatgagat tgggtaagac aaataataat ttcttattga tgaatgaaat cgtttcatta
      301 tctattgatg atcaggcgtt tagtgagggt ggtaaaatta aagtcaccca tttaattaca
      361 gaacgtaata gtattttaag aaaaatctat tttagcaaga cccaaaatgc acaaatatgt
      421 cgcatgtgtg gattagatac gcaaaggagc tatgaatgga gcgaacatat cattgaagta
      481 caccatctat taccactatc ttctcctgta agggtagaag ataaaactac ttcattaaaa
      541 gatttggttg gtatctgtcc aacctgtcat cgtgccacac acaagtacta tactttttgg
      601 cttaatttgc acaagaaaaa agattttgtt agttatgaag aagcatatca tgtatatgaa
      661 gaagctaaaa gtaaagttaa aagaatttat aaatagatag gagtatctat gttaataccg
      721 caaacctctt tatttgacca agaaaataat agaattattt cacaaagaaa attattagaa
      781 caaagtttat tacaaggtat tccattgaat gaactaatac gccagaatca aatgagctat
      841 gatgatttaa tttatattca tcatgataaa aagccttttg aaaagagaaa gaatttggtt
      901 ctaagtgatt ttcaaaaaaa ggaaaatcac attccgataa ttagtttttt ttcaggagcc
      961 ggtggattag acttagggtt tgaagcagca ggctttcaac attctatgct gattgaaaaa
     1021 atacctttat tttgtgatac attgcgtctt aatcgcccta attggtctgt gtttaatgct
     1081 gatgtttctg aaacagaaga aatggttgaa ctaatcagaa ataatattgg gtctttaagt
     1141 tttgatggtg tatttattgg aggtcctccc tgtcagcctt tctccatagc ctcaaaccag
     1201 agattctcaa aaactgataa aaattttaaa cgtgtcggct ttgagcataa gcaaaatggt
     1261 aatctattat ttaattacgt tgaattgatt aagatttttc gtcctaaagt atttcttatt
     1321 gaaaatgtct ctggattgat ggatatagat aatggtaaac agttagctag tgtatattgt
     1381 gatttacagc agcaaggcta ctcactctat aaacctcaaa taattaattc tgaatatttt
     1441 catgtacctc aacagagaat taggctattt ataattggtt atttaggaga taaaaaattt
     1501 agtccgctac aaccaaccaa taccccattg gcatgtggta atacatttga aattccaatt
     1561 attaaccaac ataaccatat tacaagagaa cattcggctg aatcgatttt acgctatatg
     1621 gaattagctt atgggcaacg tgataaaaag ggacgtgtag ataggttaga tccaagcaaa
     1681 ccatctaaaa ctattattgc tggtggcact aaaggtggag gaaggtctca cttacatcca
     1741 tatatcccaa gaacgttatc tgttcgtgaa agtgcacgat tacaaacgtt tcctgatgat
     1801 tatattttta caggagcggt tgcgcggcaa ttcacgcagg ttggtaatgc cgttcctccc
     1861 atccttgctg ctcaattagc aacagcaatt aagcattctt attttgaata gcaagcaagc
     1921 tatagcaagt tgtagccttt atacccaacc caccgtatgc gtggttgcgc cacacctacc
     1981 tgtgagtcta cgaaacttca aagccaacgt gcagtgtgtg tgcggtacgt acgcggttgg
     2041 ttgattaacg gtttgccgtt ccaactttta acttcgttga agccagcgct ttcagacggc
     2101 ctccaatgtc gtctgaaaac atcagctcca acaaagttaa aaccttaaac aacaaaccat
     2161 tccttctcca acacccaaac cacaaacaaa aatcctatgg cgcgttatcg cagaaacttc
     2221 attgccggcg gcacattctt tttcaccgtc aaactcgccg acccgaaatc gcgcctgctt
     2281 gtcgaacata tcggcttcgc gtacggctta tatggatgtg caaaaacaat atccctttga
     2341 aaccgtcgcc gtatgcgtgc tgccgaacca tatccacgcc atttggacgc tgccgcccga
     2401 cgatgcggat tattccctac tccggcggct gattaaaacc aaattctccg catattcccc
     2461 ttatactaaa aacttatccg ccggcaaaca gcggcggaac gaacgcggta tttggcaacg
     2521 gcgtttttac gaacacaccg tgcgcgatga aacggatttg cagtgttacg cggactatat
     2581 ccattctaat cctatcaaac aaagaatgtc gcgtgctaaa acagaatcct gcaaaaataa
     2641 tatcagtctt ttcaaatgcg atacttatca ttccctgact tcaaaaaaat atgtgcaacc
     2701 tgacttacgg gtttgctcct gtttgaccga taaatattct gactgcctca aagggcaaaa
     2761 aataatgtgg gtatgttgag gctgcctctt tttgaaatga caaacaaaat gccgtctgaa
     2821 acccgatttc cggtttcaga cggcatttga tgtttaatca gttgtcaaac ctgattatgc
     2881 caaacctttt gccttcaaca cttccagcat cgtcgtgccc aactcggcag ggctgcgggt
     2941 gtaagcgata ccggcttttt cgaaagcggc gaatttttcc tcggcagtac ctttgccgcc
     3001 ggaaataatc gcaccggcgt ggcccatacg tttgccttta ggagcggtaa caccagcaat
     3061 gtaacctaca acaggtttgg ttacgttgga ttggatgtat tcggctgctt cttcttccgc
     3121 agtaccgccg atttcaccga tcatgatgat ggcgtcggta tctgggtctt cttggaaaag
     3181 tttcagtgcg tcgatttggt tcataccagg aatcgggtca ccgccgatac caatacaggt
     3241 tgattgaccc aagcccagtt tggtggtttg tgccacggct tcgtaagtca atgtaccgga
     3301 acgggaaata ataccgatgc ggcccggagt gtggatgtgg cccggcataa taccgatttt
     3361 gcactcgccc ggagtaatca cgcccgggca gttagggccg accaaacggg taccgttgcc
     3421 gttggtttcc aaataacgtt tggctttgag catgtccaaa gtaggtacgc cttcggtaat
     3481 cacaacgacc aagcctacgc ctgaatcaac ggcttcaacg atagaatcca acacaaacgg
     3541 agcgggaacg taaattacgg atgcatccgc gccggtttct ttaacagctt ctttcatggt
     3601 gttgaataca ggcaggttca ggtgggtttg accgcctttg cccggggtaa cgccgccgac
     3661 aactttagtg ccgtaagcca gagcttgttc ggagtggaaa gtaccgtttt taccggtgaa
     3721 accttgaacc aatactttgg tgtctttatt aatcaatacg ctcattcttt tctccttagg
     3781 cgtttacggc tgcaacaatt ttttcggctg cgtcattcag gccgtctgca gaagtcagtt
     3841 tcaggcctga ttcgttcagg attttcgcgc cgagttcggc gttgttgcct tccaaacgaa
     3901 caacgacagg aacgtcgacg ttgatttctt taacggctgc cacgatagct tccgcaatca
     3961 tgtcgcaacg tacgataccg ccgaagatgt tgatcaatac gccttgaacg gatttgtctt
     4021 ccagaatcag tttgaacgct tcaaccacgc ggtctttggt tgcgccgccg ccaacgtcca
     4081 agaagttggc aggttggccg cctttcagtt tgatgatgtc catggtggcc atcgccaaac
     4141 cggcaccgtt aaccatacag ccgatattac cttccagggc aacatagttc aggtcgaatt
     4201 cggaagcttt cagctcgcgt tcgttttctt gagatttgtc gcgcaattcg gcgattttcg
     4261 gcaggcggta gagcgcgttg ctgtcgatgc cgattttgcc gtccacgcaa gccagtgcgc
     4321 cgttttcgcg aactgccagc gggttgactt caaacagggc gaagtcgttt tcgacaaacg
     4381 ctttgtacgc gccggtcatc agtttgacga actcgttgat ttgtttgtct ttcaagccca
     4441 gttggaaggc aacttcgcga gcttggcaag gttgcaggcc gaccagcgga tcaacggtta
     4501 ctttgaagat tttttctgga gtttcggcag caactttttc gatttccaca ccgccttcgg
     4561 tagaagccat gaatgtaacg cggcgggtag aacggtcaac cactgcgccc aagtacagct
     4621 cggtttgaac cggatacata tcttcgcaaa ccaaaacgct gttgacaggt tgaccgttgg
     4681 catcggtttg gtaagttacc aagttggtgc caatcaggct ttcagccact tctttagctt
     4741 cttcgcggct tttaacgact tttacgccgc ccgctttacc gcggccgccg gcgtgtactt
     4801 gtgctttgac aacagcgaat ttgccgccca atttgtcgta agctgcagcg gcttcttcgc
     4861 cgttgtgtgc caaaataccg ccttgtacgg gcaaaccgta gccagccagc agttctttag
     4921 cctgatactc gtgtaaattc atggatttct cctttagatt agtgtaatgc cccgagtttg
     4981 cctccaaatg gcaagcccgt gcgtttcaga ctacctttcg gcggtcggaa aatcgtcgtt
     5041 tcacttgctg aaaggcaacc acatccgcgc cagcagatac atggctgcac cgcctccccc
     5101 gagaataaaa aagacaatgc cttttttacg cgaattcgga cagagcagat aaacggcaag
     5161 gctgaaactg ataaacaaca atgccacgcg ccaaaccaat tctttatctt tgaaacggtt
     5221 gagcgtataa gtttcggtca tcatcacata catctgccac aatgcggcca tacacatgct
     5281 gatgatgccc atcggtataa agaaaatacc gactatttct ttgttcataa cgaatgtaaa
     5341 tgctgtttgt ttgtctgacg gaattataaa tcagaaaacg aagctctcgg aacattcaat
     5401 ttgtcggagg ccttaatgtc tatcaaccgt gcaaagcgcg tttgtcggcc gccaatgcag
     5461 cttcgtgaac cacttcggac aaggttgggt gggcatggat aatgcgggcg atgtcttcgc
     5521 tgctggcgaa gaattcgagc gcagtcacgc cttcggtaag caattcgctg acaaccggac
     5581 caatcatgtg tacgcccaag atgcggtcgg ttttggcgtc tgccaacact ttaaccgtac
     5641 ctttggcttt gcccattgcc aatgcgcgac cattcgcacc aaaacctgaa gtaccttttt
     5701 tgtactccac gccttcggct ttgagctgct cttcggtttt acccacccaa gcgatttcag
     5761 gatcggtgta aatcacgaac ggtacgttgt tgaagtcgat atgcggtttt tgaccggcaa
     5821 tgcgttcggc aacggcaacg ccttcgtcgc tggctttgtg tgccaacatc gggccgcgaa
     5881 ccacgtcgcc gattgcccat acgttaggca ggttggtacg gcattcgcca tctactttga
     5941 taaagccgcg ctcgtctttt tccaagccta cggcttcggc gttcaggcct ttggtgtttg
     6001 gaatacggcc gatggcaacg atcagtttgt cgaatacttc ggttttggct tcgccggcag
     6061 cagtttcgta agcaacggaa acacctttgc cttcagactt gatgtcgccg attttcacgc
     6121 ccaattcgat gctcagacct tgctctttgg tgaagtattt gaaggcttct ttggcgattt
     6181 gttggtcggc ggcagccagg aaggtcggcg cggcttcaag aatggtaact tccgcaccca
     6241 cgcggttcca tacggaaccc atttccaaac caatcacacc ggaaccgatc acgccgagtt
     6301 tggcaggtac ttcggtcagg ttcaatgcgc cttcgttgtc caatacgttc acattgtcga
     6361 tagcgacttg tggcagcgga cgcggtacgg aaccggtcgc tacgatgacg tgtttggctt
     6421 cgataacggt tttctcacct ttgttatcga cttcgatttg gtaagcatcg ccatttttgc
     6481 cggcaaagga agccgtaccg aacaggctgg ttactttgtt tttctggaac aggaatttca
     6541 cgccgccggt cagtttggtt acgatggcat ctttgcgctc aatcattttg gccacgtcga
     6601 attttacgtc gccgacagtg ataccgtgtt cggcaaactc gtgttgcgct gcgtggaaat
     6661 gttcgctgga ttgcaacagg gctttagaag ggatacaacc tacgttcaag caagtaccgc
     6721 ccaatgcagg ggcattgcct gctttgttaa cgcctgcatc gacacaggca gttttgaaac
     6781 ccagttgtgc ggcacggatg gcggcaacgt atccgcccgg gcctgcacca atcactacta
     6841 catcatattg agacatcgtg tcatcctttg cttttagcag tatctcaaaa taaaaacgat
     6901 acttttcgtt tcttttttat tttgaatgac tgcgttttga tggttttaag aaaaagccgt
     6961 ctgaaagtcc atatctgccg attcattcga atcaaatgtt tcagacggtc tcaatcgttt
     7021 gttgagccta ttgtagcacg atactacatt acgctacatc taaatatagt ggattaaatt
     7081 taaatcagga caaggcgacg aagccgcaga cagtacaaat agtacggcaa ggcgaggcaa
     7141 cgccgtactg gtttaaattt aatccactat aaaaattcag acggcctttt cattaacaaa
     7201 taaaaggccg tctgaaacga ttacagatcc aacaacaggc gggctgggtc ttccaacgcg
     7261 tctttaatgg ctaccaaggt caatacagct tcgcggccgt caatgatacg gtggtcgtaa
     7321 gacagagcca gatacatcat tggacggaca acaacttggc cgttttcaac cacagcgcgc
     7381 tctttagtgg cgtgcatacc caaaatcgca gattgaggcg gattgatgat cggggtggac
     7441 atcatagaac cgaaagtacc gccgttggta atactgaatg taccgccggt cagatcttcg
     7501 atagcgattt tgccgtcttt ggcttttttc gcgtaatcaa caattgcttg ttcaatgtcg
     7561 gcaatgctca tttggtcggc atcgcgcagg attggcacaa ccaaaccgcg tgggctgcca
     7621 atcgcgatac cgatgtcgaa gtagccgtgg tacacaatgt ctttgccgtc aacagaagca
     7681 ttcacaaccg ggtatttttt cagggctgca acagcggctt taacgaagaa ggacataaag
     7741 cccagtttca cgccgtgttc tttctcgaat ttttctttgt acttcgcacg caagtccatg
     7801 attggtttca tgttgacttc gttgaatgta gtcagaatgg cgttttcttg ttgagaagcc
     7861 aagaggcgtt ctgcaacacg ggcacgcagg cggctcatcg gtacgcgttc ttcaggacgt
     7921 gcgccggcag gaagtgcaac ggcaggagca gcggctgcgg caggtttggc tgcggcattt
     7981 tgtacgtctt ctttcaatac gcgaccgtca cggccggaac cttgcaatgc gttcacgtca
     8041 acaccgctct ctgcagccag tttggcggcg gcaggcatag cggcgttgtt ttgtgcagca
     8101 gcaggagcgg cggccggggc agcttcggca ggagcggcgg caggtgcttc agcagcggca
     8161 gtagcagcgg tatcgatacg tgccaaaact tggtcggcaa caacggtttc accgtcttgc
     8221 gctacgattt caaccaatac gccggcttgt ggagaaggta cttccaaaac cactttgtcc
     8281 gtttcgatat cgatcaggat ttcgtcacgg gcaacggctt cgccaacttt tttcttccat
     8341 tccaagagcg tgccttcaga tacgctttca gacagcatag gtacttttac atcaataatc
     8401 attttgtgtc tccaatggcc ctttcagacg gcctgttgtg tgtttttcat tctgcatatg
     8461 ggcattccgc ctgagcagcc tcagacggaa tgctgcttgg tttacaacgc caaagcgtct
     8521 tcaaccaatt gtttcaattg agcaatgtgt ttgcttgagt agcccactgc aggcgatgcg
     8581 ctgcttggac gaccggcata agacagtttt tgctcttcgc tgataacgtc ttcgatgcgg
     8641 tggcggattt ggtagaacgc gccttggttt ttcggctctt cttgcgccca aaccacagat
     8701 tttgcgttcg gatatttcgc cagttcggct ttaacctcat cgtatgggaa cggatacagc
     8761 tgctcaacgc ggacaatcgc aacatcatct tccagtttac gttcggctcg accggcttcc
     8821 aagtcatagt aaacctgacc ggcacacaat accacgcgtt tcacgctgtc gttgcttgcg
     8881 cgttcggcgg tatcgccgac aaccggacgg aaagtcgaac cttcggtgaa gttttccagc
     8941 gggctcattg cccctttgaa tcgcaacagg cgtttggaca tgaaaattac cagcggtttg
     9001 cggtatgaac ctaagacttg acgttgcaag aggtggaaca tttgcgacgc ttcagatggc
     9061 atgatgactt gcatattgtt ctcagaacac agttgcaacc agcgttctac gcgtgcagaa
     9121 gagtgctcag ggccttgacc gtcgtaaccg tgcggcagga tggtggtcag accgcacaag
     9181 cgaccccatt tggtttcgcc tgaagacagg aattggtcaa tagtcacttg cgcgccgttg
     9241 gcgaagtcac cgaattgagc ttcccaaatg gtgagcttgt caggagcgga gcaggcaaag
     9301 ccgtactcga acgccatcac ggcctcttcg ttcaagatgg agtcgataac caggaactcg
     9361 cccattcctt cgcccatatg gcgcagggga acataagtac cgtcgtccca tttttcgcgt
     9421 ttttgatcgt gcaatacggc gtggcggtgc gagaacgtac cgcggccgga gtcctcaccg
     9481 gagatacgca cgccatgacc tttggttacg aggctggcgt atgccaaggt ttcggccata
     9541 ccccaatcta tggcctgttt gccggatgcc atggctttac gcgcttcaat cacacgtttt
     9601 gcagtcggat gcagggcaaa gccttccggt acggcggtaa acttctcagt gagacgctca
     9661 atatctgcgg caggcaaacc ggtttcgatg tgttcgcgcc aatctttgcc ttggtatttg
     9721 ctccagtcga tttgcgtgcg ttgaaagttg ctcaacgttg tttgctcgac gtgttcgcct
     9781 ttgtccaaag catcacggta ggcttggatg taaccgtctg cctcggcttg ggttaccacg
     9841 ccttcggcaa tcagttgctc ggtgtacaaa gcacgcgcac cggggtgttg cgatactttt
     9901 ttgtacatca tcggttgggt caaggtcgga tcatcgccct cgttgtgacc ccatttacgg
     9961 tagcagacaa cgtcaatcac gatgtcttta tggaattttt tgcggtaatc caaagcggct
    10021 tggatggcaa agcaaacacg ctcaggatca tcgccgttca catggataac cggagcggaa
    10081 accatttttg cgatatcggt acagtgtacg gttgaacggg tatcgcggat atcggaagtg
    10141 gtaaagccga tttgattgtt gatgacgata tgaaccgtac cgccggtggt ataaccgcgc
    10201 gttttagaca ggttgaatgt cgcttggttg acacccaaac cgataaatgc ggagtcgccg
    10261 tgaatcaata cgggcaagac tttatcgcgg ccgttttcgc ccaaacgttt ttgcttggcg
    10321 cgtgcagaac cttccactac cggattgacg atttccaagt gggacgggtt gaacgccaaa
    10381 gaaacatgca tcgggccgtg cggggtagca atatcggagc tgaagcccat atggtatttc
    10441 acgtcgccgc tgggcagttt gatttcggca cgaccttcaa attcggcaaa caaatcgccg
    10501 ggttttttgc ccaaaatgtt caccaaaaca ttcagacggc cacggtgcgc cataccgatg
    10561 atgacttctt ccacgccgtc tttaccggcg ttttgaatca ggtagttcaa accggcaatc
    10621 gcgctttcgc cgccttcgac accgaaacgt ttctgaccga catatttggt atgcagataa
    10681 cgttccaaag tctcggcagc agtcatctct ttcaagatac ggcgtttttg atcggcattg
    10741 taatgcggtg tggacaatac gctttcaaaa taattgcgta cccagcggcg ctcttcggta
    10801 ttgggaatat agatatattc caatgcgatg tggccgcagt aggtttgttt gaggttgctg
    10861 atgatttggg acaaaggcag tttgccgcga ttggcaaaat cgccctcgcc catattgaat
    10921 tgaagcgcca tatcggcatc agacagaccg tggaatttcg gatcgagggc ttcaatatcg
    10981 cgcgggggga tacgtttgag cggatcaagt tgggctgcac ccacgccttg gatacgatag
    11041 gcagaaatca gccgtaaaac gctgacttgc tttttcagca ttgcctcatc cgcaccgccc
    11101 gcaacggcag atgcaatttt ctttttcgcc aaagtaacaa atgattcgcg aatcggtgtg
    11161 tgtgcgacat cgacagcaac cgtccccggc tgtttgctca aatcggtgaa atactgcttc
    11221 catttttcat caaccgtatc ggggttttcc aaaaaagcct cgtacaattc ctcaatgtag
    11281 ggtgcgttcg aaccgaacag gtaagagaaa ttgagttttt cgtccatcat ggcgtgcgct
    11341 cttttcttta aaatataaac aaagggtaga agtccgcgtc ctgacggcta aactgatgcc
    11401 gtctgaaaag acattttatt ctaccctatt ttaaaccgga ttgcttgtct tgatttcatc
    11461 cgactacaat cagacggatt cgggaaacaa tccggttctc tgatattgcc tgtttgacaa
    11521 tatattaatg tatgttacct ctcgcctggc ggcacataat cgcggcgttc cgaaccggta
    11581 taaagctggc gcgggcggcc gattttcagc gaaggatcgc taatcatctc gtgccagtgc
    11641 gaaatccagc ccacgctgcg cgacagggcg aagatgacgg taaacatttc ggtcgggatg
    11701 cccagcgcgg acaggacgat gccggaatag aaatcgacgt ttggatacag tttgcgttcg
    11761 ataaagaacg ggtctttcag cgcaatctgt tccaattcca tcgccagttt gaatttcgga
    11821 ctgtcttcca agcccaattc cttcaaaact tcatagcagg tttcgcgcat aatgctggca
    11881 cgcggatcca tattgcggta cacgcggtga ccgaagccca tcagacggta tttgcgttgt
    11941 ttcacacctt ccatgtatgc ggcaacatta gacacatcgc cgatttcgtc caacattttc
    12001 aacacggctt cgttcgcacc gccgtgcgaa gcaccccaca ggcaggcgat accggcagca
    12061 atacaggcaa acggattcgc acccgaagag cctgccagac ggacggttga agttgaggcg
    12121 ttttgctcgt ggtcggcatg caaaataaag atgcggtcga gcgcgcgtgc caaaacggga
    12181 ttgggtttgt agtcttcaca cggcgtggcg aacatcatat gaaggaagtt ttcggaataa
    12241 gaaagattat tcttcggata attgaacggc agaccgtttg aatagcggta gcacattgcc
    12301 gcaatggtcg ggattttaga aatcaggcgg taaatcgcga ttttgcggtg ttcgggattg
    12361 ctaatgtcca agctgtcttg gtagaacgca gacagtgcgc cgaccacgcc gaccatcatc
    12421 gccatcggat gcgcgtcgcg gcggaagccc cggaagaacc aagtcagctg ttcatgcacc
    12481 atcgtgtggc ggcggacggt attgtcaaat tctgcctttt gctcgggagt cggcagttcg
    12541 ccgtaaatca acaggtagca gacttccaaa taatcggact tttcggccag ctgctcgatg
    12601 gggtatccgc gataataaag caagccttga tcgccgtcga tgtaagtaat tttagactca
    12661 cagcttgcgg ttgaaacaaa tccggggtcg aaggaaaaca aacctgtatt ttttgtcagc
    12721 ccccgaatgt caaccacatc gtgcccgatg ctggcttcca ataccggcag ctccaaacct
    12781 gcctgacccg gtacgttgag tttgattgat ttggacatat tattgctcct ttgcaagtta
    12841 taacccacgt tactgcatcc gcagcacgtt ctttgccttc agacggcttt tgcattttga
    12901 aatctgcctg caggcagatt tcagatgcct catgcccgtc tgattttttc aagcatcggg
    12961 ataaggtgcc ctttgtccgt ttccgaatgc ccgttaatca aggcaagcaa ttcttgatct
    13021 tgaaattcaa ggatttcgga aaactcggac agctctttat cgctcaaatg ctcgaattct
    13081 ttttccataa acctgccgaa gattaaatct aactccaaca atccccggcg ggtttgaaaa
    13141 cggattttcc gtttggcaat atcgtcaaaa accatcattt cttaaacggc ccgtttcaac
    13201 ataatctctt taatcttacc gatggctcgg gtcggattca agtgtttggg acatacgtct
    13261 acgcagttca taatggtgtg gcaacggaac aaacggtatg ggtcgttcag attatccaaa
    13321 cgctcattag tgatggtatc tcggctgtcc gcaatgaagc ggtaagcatt cagcaaaccg
    13381 gacggaccaa cgaatttatc agggttccac caaaatgacg ggcaggcagt cgaacagcag
    13441 gcgcacaaaa tacactcgta caaaccgtcc aactctttac gctcttcctg agtttgcaga
    13501 cgctctttgt ccgcatcaat cggattatcg ttgacaacat aaggtttgac ggaatggtat
    13561 tgtttgaaga actgggtcat atccacaatc aggtcacgga taacaggcag acctggcaga
    13621 ggacgaattt taaccggctg tttcaagcca cgcagatcgg tcaaacacgc caagccgttt
    13681 ttgccgttga tgttcatacc gtcagaaccg caaatgcctt cgcggcagga gcggcggaaa
    13741 gacaaggtat cgtcttgtgc tttcaggcgt accaaagcat ccaaaagttt cacgtcggtc
    13801 ggttccaatt ccaactcgta acgctgcata taaggcttgg catcaacatc cgggttgtaa
    13861 cggtaaattt caaaactcat tttttccatg agaagtgttc cttttctcat caactgccca
    13921 atgattttgt attataaatt caagcagttc aatgtgggta tggttagatt tcagacgagc
    13981 ttatgaggcg aaaaccgtct gaaaacgcat caataaacgc gcttggccgg tttgatgtat
    14041 tccacgctca aaggcttggt atgtaccggt ttgtaagaca aagtattggt atctgaatgg
    14101 tacagcgtat gtttcatcca gttttcatca tcgcgctcag gatggtcgtc tgaagcgtgc
    14161 gcaccgcgtg attctttacg tgcttcggca gacaccaaag tcgctttcgc cacttcaatt
    14221 aggttatcca attccaaagc ctcgatacgc gcggtattcc acactttgct cttgtctttg
    14281 atttcggtac gtttcacacg ctcggcaatc gccatgactt ctcgaacgcc tttgctcaga
    14341 atctcatcag tacggaacac gccggcgtgc agttgtacgg agcgttgcaa ttcgcgacgc
    14401 aatgcatcaa cgttttcgcc atcagtttga ttgtccaaac gctcgatacg ttggcgggtc
    14461 agctcgcccg catccgcagg caaaggtttc cagtcgcttt gctctttgat gaatttaatc
    14521 atgctgtcgc cggcagcttt accgaatacc accaagtcca acagggagtt ggtacccaag
    14581 cggttcgcac cgtgtacgga agcacaagcg cactcacctg ccgcatacag accttttaca
    14641 ggcacttcgt attcgtcgcc ttgaggaacg acaacttcgc catggtagtt ggtcggaata
    14701 ccgcccatca tatagtgggt agtcggcaca acgggaatcg ggtctttaat cggatcgata
    14761 ccggcgaact gaatggaaat ctcgcggatg cccggcagtt tttccataat tttttctgcg
    14821 ccgatatggt cgattttcag taagacatgg tctttgtttt taccgcagcc gcgaccttcg
    14881 tagatttcca tcgccatcgc gcgggaaaca acgtcgcgag aagccaagtc ttttacggtc
    14941 ggcgcatagc gttccataaa gcgttcgccg tcggcattca acagaatacc gccctcgccg
    15001 cgtacgcctt cggtaatcaa cacgcccgca cctgccacgc cggtcgggtg gaattgccag
    15061 aattccatgt cttccaacgg gatacctgca cgcgcgcaaa tacccaaacc atcgccggta
    15121 ttcatatagg cattggtaga agaggcataa atacggccgc cgccgccggt agcaaacatc
    15181 acagctttag cgtggaaaat ataaacttcg ccggtttcca tttccatggc ggttacgccg
    15241 acgacatcgc cgttttcatc acgaatcaaa tcttgtgccg tccattccac aaagaattgc
    15301 gtattggcac ggacgttttg ttggtacaaa gtatgcagca tcgcatgacc tgtacggtcg
    15361 gcaaccgcac aggcgcgttc taccgcgcgt ttaccgtgtt cggcagtatg gccgccgaaa
    15421 ggacgctgat aaattttacc gctttccaca cggtcaaaag gcatacccat gtgttccaac
    15481 tcaatcaccg cttcaggcgc agcgcggcac ataaactcaa tcgcatcttg gtcgcccagc
    15541 cagtcggaac ctttcacggt atcgtacatg tgccagtccc aacggtcctc ctgcacatta
    15601 cccaaagagg cggaaatacc gccctgcgcc gctacggtat gcgaacgggt cgggaacact
    15661 ttagacaaaa cagcacaatt cagaccggat ttggataatt ggagggctgc gcgtaaacct
    15721 gcaccaccac cgccgacaat cacggcatca aacttgcgaa caggaaaacc catacttacc
    15781 cccaaattac tttaattgaa tacaccaagc agccgaccag ccagacgatg gtggcaacct
    15841 gcaaaaacaa acgcacgccg aagggtttga tatagtccat ccacaaatcg cggataccca
    15901 cccaagcgtg caagaatacg gcgatgaagc tcacttgggt aaatactttt acccaagttt
    15961 gactaaaaaa tgcctgccat gccgaatatt ctttaggcag ggaaaataga accactaaaa
    16021 gtgcaacggt ataaatcaac ataataaccg cagtcgcacg ttgcatcgcc caatcgcgca
    16081 aaccgtaatg ggcaccggtc aatttacgtt ctaccataac aacgctccca aaacgacagt
    16141 caaaaccaat gcagaagcaa atacggcttt agcggtattg cgcgcagtat tcagctcaag
    16201 gcctttgtgc gcatccaaaa ataaaaagcg gataccggcg agagaatggt gcagataagc
    16261 ccacaataca ccgattaaaa ccagcttgac caaaggatgg gaaacaatgg cacggtaagt
    16321 ttcaaatgca gactcttgac tcagggtacc ggacaggaaa tacagcagga aaggcagcat
    16381 aataaacagc ccgaccccac tgatgcggtg aaggatggaa actatcccgg gtatcggcag
    16441 acggatgttc ggcaaatcca gataaacagg acgcggtttg gcagacatag tcaattcctc
    16501 tgtagttata tatcgactca aaaaccgtaa acccattgct acactgggtt acataaacgt
    16561 taatttacct gttttatccc attttgaaca gtgtatttta aaaacaaact gatagatttt
    16621 gacaaacacg cgtggaaaca gcagattaaa agaaagattt ttagttttgc cgcccccttc
    16681 ccgacacggt atcagcatcc gaccccatcc ccaaaaacaa aatgccgtct gaaaaaattt
    16741 cagacggcat tgttttgcca tatcggtcag gctttcaatt tcgcatcggc atcgcgcaac
    16801 gcggtacgca gaccttcctc gataacggga tggtagaacg gcatatccag catttgcgga
    16861 acggtcatct tcatttgatg cgcccatgcc aacaagtgcg ccaaatgttc ggcggcaggg
    16921 cctacgattt ccgcgccgat aaagcggccg gtggcttttt cggcatacag gcgcatatgg
    16981 cctttgttta ccagcatcac gcggctgcgg ccttggtttt tgaacgatac ttcgccgatg
    17041 acaaattcgt cggcttggta ttgcgcggca acctgcgcgt atttcagacc gacaaagccg
    17101 atttgcggac tggtaaacac cacgccgatg gtgctgcggc gcaaaccgcc gccgatattc
    17161 gggtagcggc tcgcgttatc gccggcaatc ttgccttggt cggcagcttc atgcagcaga
    17221 ggcagttggt tggacgcatc gcctgcgatg aagatatgcg gaatactggt ctgcatggtc
    17281 agcggatcag caacaggtac gccgcgcgca tctttttcga tattgatatt ttccaaaccg
    17341 atattgtcaa cgttcggacg gcggcccacg gctgccagca tatattcggc aacaaatacg
    17401 cctttttcgc catcctgctc ccaatggact tctacattgc cgtctgcatc gagcttgacc
    17461 tcggttttag catccaaatg cagtttcaat tcttcgccga acacggcttt cgcctcgtct
    17521 gaaacgacgg ggtcggaaat gccgccgatg attccgccca aaccgaaaat ttcaactttc
    17581 acgcccaaac ggtgcaatgc ctgacccagt tccaaaccga taacacccgg cccgaacacg
    17641 gcaacgcgct taggcagcgt atcccatgag aaaacgtcat cgttgataat caaacgattg
    17701 cccaaagact gccattgcgg caggatgacg ggacgcgaac cggtagcaat cacgaaactt
    17761 tttgccgtaa tttgagtatg ctcgtcgatt tggacggtat gctcgtcgat aaatttagcc
    17821 gaacccataa tgcgcttgtc ggcaggccac tcttccacat cggcaacgac aaagccgaca
    17881 aaacggtcac gctcggattt aacgcgctgc atgacctctt cgccgttgac gacgatgctg
    17941 tctttgtcca aatgcacgcc gaacgggtcg gtatgcaatg cgtgatgacg cgcctctgcg
    18001 gcggcaatca agagtttgga aggcatacag cccacgcgcg cgcaggttgt gccgaacaca
    18061 ttgttttcaa tcaggtaaac attatccgaa tgtaaacggg cattgcgaaa cgcacccata
    18121 ccggcagtac cgccgccgat tacgacgaca tccgcttgaa tttttttcat aatctttgtc
    18181 cttccgtttt cgtctgaaac attgccgaca cagaacatat cggtttcaga cagcatttaa
    18241 atattttccc aatcaaaaac atcattcaga taaataaaaa caaaatttcg attgagtgca
    18301 acaatatcca aattctctta taaatataga gttattcgga gcggcagtgt agaaccgccc
    18361 gaataactct atccggtata tcagacagtt taatcaaacc gccttaagca aacagctatc
    18421 agtttttagc caagtaagct tccaaatctt cgctgccgcc gatgtatttg ccgccgatga
    18481 agacttgagg ggcagtcatc ttgccggtaa tggcgcgaac ggaagtaacg gttgcatctt
    18541 tgcccaatac gatttcttcg taagacaaac ctttgtcttg caaagcttgt ttggctttag
    18601 cgcagaattg gcaacctggt ttagtgaaaa ttgccacaga ctcttgagcc ttccaatcgg
    18661 gagcaacgaa ttgcagcata gtatctgcat cggatacttt gaacggatcg cccggttctt
    18721 caggttcgat gaacattttt tcaaccacgc cgtcgttaac cagcatggag taacgccaag
    18781 agcgtttacc gaagcccaag tcttctttac cgaccagcat acccatacct tcggtaaatt
    18841 cgccgttgcc atcaggaatc atgtagatgt tgtcggattc ttcttcggca gcccaagcgt
    18901 tcattacgaa cgtatcgttt acagatacgc agtagattgc gtcaacgccg ttttctttga
    18961 acgcgccgaa caattcgttg taacgcggca ggtgtgaaga agaacaagtc ggggtaaatg
    19021 caccgggcag ggagaatacg actacttttt tgcctttgaa caaatcatcg gtagacacat
    19081 ctttccaagt gtcgccgacg cgggtgcgga atactacgga aggtactttt tgaccggtac
    19141 gatcttgcaa agccatttta agctccttaa tagattggtt tgagaaataa ttgtgaatcg
    19201 ctgggcattc taccccgaat aagtcgattt gtataattta tagttcaaat aatattaatt
    19261 actcaaaact attaatcacc aacctcgacc aactttttac agtatataaa gccatgccta
    19321 aaaaaaacaa gtcttatttg agaaaaattc ttagaaactc ccctacgccc atttgaaaac
    19381 agaaatgccg tctgaaaagt attcagacga catccgatca cgttatccct gcttatttcg
    19441 ccagttcggc acgcagtttg tgggttacgt tcatcatcac ttggagttgt tccagagttt
    19501 ctttccagcc acgggttttc aggccgcagt ctgggttaac ccacagacgt tcaaccggta
    19561 caacctcgat ggctttgcgc aacagatgct caacttcagc ttcagtcggt acgcgcgggc
    19621 tgtggatgtc gtaaacgccc gggccgatgt cgttcgggta tttgaattcg ccgaacgcgg
    19681 tcaagagttc catatcggaa cgtgaagttt cgatggtgat gacatcagca tccatagcgg
    19741 cgatggcagg taggatgtcg ttgaactcgg agtaacacat atgagtgtgg atttgggtgc
    19801 tgtcttcgca accggcagag gacaggcgga aggattcgcc cgcccagttc aggtaggcat
    19861 cccaatcggc gcgtttcagc ggcaagcctt cgcggatggc aggttcgtca atttggatga
    19921 ctttgatgcc ggctttttcc agatccaata cttcgtcgtt cagagccagt gcgatttgtt
    19981 tgcacacggt agagcgagga atgtcgttgc ggacgaaaga ccattgcaga atggttacag
    20041 ggccggtcaa catacctttc atcgggcgtt tggtcaggct ttgtgcgtaa gtagaccaag
    20101 ccacggtcat ggcttcagga cggcttacgt cgccaaagat aatcggtggt ttcacgcagc
    20161 gtgagccgta gctttgtacc cagccgtatt gagtgaatgc aaaaccgctc aacaattcgc
    20221 cgaagtattc aaccatgtcg ttacgctcgg cttcgccgtg taccagtacg tccaagtcca
    20281 gtttttcttg ctcttcaacc accaaggcga tttctttttt catcgcggct tcgtaatcgg
    20341 cggcagacag ttcgcctttt ttgaaggctg agcgtgcctg gcggatttcg gtggtttgcg
    20401 ggaaagaacc gatgttggta gtcggtagca gaggtaggtt caaccatgct tgttgcgctt
    20461 tgatacggtc ggcaaatgga gatttgcgtt ggtctgcgtt ggcaggcaaa tcggccaggc
    20521 gtttggcaac gtctgcacga tggatttcgc tgctgttggc acgggagtcg gcagcagctt
    20581 ggctggcggc gagttcttcg gcaacagaat cacggccttc gttcaatgca gctttcagaa
    20641 cgcgcaattc ttgggttttt tgcagggtga atgccaacca agagtacagg tcgggtttgt
    20701 tggctttcag tttttcttca actgacaagt caaatggagt gtgcagcaga gagcaagagc
    20761 tggaaatcca caaacgatcg cccagtttgg cttgcagagg ctcaacagtt tccaaaactt
    20821 tgttcaggtt ggcgcgccag atgttgcggc cgtcgatgat gcctgcagac agaactttgt
    20881 cgtagtcggc aaatgcgtcc agttgctcgg gagcgcgtac caagtcgatg tgcaggccgt
    20941 caacaggcag ggatttcaac aatgcggcgt gttcggcaac agaaccgaag taagtgctca
    21001 gcaggatttt ggcacttact ttgctcaaag tagcgtaaac gtctttgtat gcttctaccc
    21061 attctttagg cagatcgaca gtcaaagcag gctcgtcgat ttgaatccac tcggcaccgg
    21121 cttcaaccaa cgcagtcagg atttcaacgt aaacaggcaa cagtttaggc aacaggctca
    21181 gacggtcgaa tgcgacttca cctttttctt tacccaccca caggaaagtc aacggaccaa
    21241 caacggtcgg tttggctttc aagccgaggg cttgggcttc tttcagttgt tggacgtaat
    21301 gtttggcgtt ggctttgaat tcagtatcgg cgtggaattc aggcaccaag tagtggtagt
    21361 tggtgtcgaa ccatttggtc atttcgatag cgaattggtc tttgttacca cgggccagtt
    21421 ggaagaattg ttccaaagac aggttttggc tgtcgaagcc gaagcgggcg ggaatcgcgc
    21481 cggtagcgac ttgcaggtcg aggatgtggt cgtagaaagt gaaatcgcct acggcaacgt
    21541 aatcggcgtt ggcggcagct tggtgtttcc agtttttctc gcgcaagtct ttggcaacag
    21601 ccagcaattc ttgctcgctg atttctttgc gccagtattt ttcttgggca aatttcaatt
    21661 cgcggaaggc gccgacacgc gggaagcctg aaaaatgtaa tgttgtcata taaactctcc
    21721 agttggattt tgtaaggacc ggttcgatcc gaatcggccg gtattgtaaa tcagaatggc
    21781 ttagatgggg cggcgttttg cttttcagac ggccttggat gccgtctgaa gccgttttcg
    21841 gctttaaggg cgcacgccta aaatatggca gatggcgtaa gtcagctcgc tgcggttgag
    21901 cgtgtagaag tggaaatctt tcacgccttc gcgggacagg actttaacca tatcgatggc
    21961 gatacttgcc gccaccagat tgcgcgtgcc ttggtcatcg tccaaacctt catacatttg
    22021 cgacagccag cttgggattt tgacattggt cacttgcgcc attttgccca gttgtttgaa
    22081 attggtaacg ggcaggatgc cggggacgat ttccacatcg atgcccaaca tcacgcagcg
    22141 gtcgcggaag cgcaggtagc gttccacatc aaagaaaaat tgggtgatga cgtggtttgc
    22201 gcccgcatcg attttgcgtt tcagattaat caggtcggct tgtgcggatt tggcttcggg
    22261 atgtacttcg ggatatgccg ctacggaaat gtcgaagtcg gcgacggagc gcaacagttt
    22321 gaccaagtct tcggcgtaaa acggtttttt ctcataaccg ggcggctcgt cgccgcgcag
    22381 ggcgacaatg cggcggatgc cgctgtccca ataatctttg gcaatttggc gtaattcgtc
    22441 gggggatgcg tcgatgccgg tcaggtgcgg cgcggcttcc aagccggttt cctgcttgat
    22501 gcgtttgacg atgccgtgcg tgcggtcgcg ttcgccggag ttggcgccgt aagttacgga
    22561 tacgaacttg ggatgcaggg tttgcagacg gtggatggaa tcccacagca tcgtttccat
    22621 ttgttcgttt ttcggcggga aaaattcaaa cgaaacgttg atgtcgcctt tcaaatcgga
    22681 aaggctgttg tttaacgcat tgatttcttt tgcgtaattc attgctgtgt accttttatt
    22741 atcttttata tgatatttca ggcgacataa taaagttgca ccgaatatga gtcaatttca
    22801 aaattttcag gtttatgatg aaaattttta atatttcgca aaaacaatct gcttttcttg
    22861 tacaagcctt ctaaattatg ataaagtttg ttatgttata acacttcaag taaggcgata
    22921 tatgaaaccg aatattcatc ctgacaatta ccggaccgtc ctttttttcg acagcagtgc
    22981 caatgaaggc tggctgattc gttcttgcgc cgaaacacac ggaaaaacga tggtttggac
    23041 agacggcaaa gaatatccgc tgttttcgct ggatacttct tctgcatccc atcccgtcta
    23101 taccggcaaa cagcgcaacg tcaataccga aggccgtgcc agcaaattca accaacgttt
    23161 ccaatccgtc atgtcatcgt ttagaaagga caaataatgc aggttctgtc ttcactcaaa
    23221 accgccaaac aacgccaccg cgactgccaa atcgtcaggc gcaggggcaa agtttacgtc
    23281 atctgcaaaa gcaatccgcg ttttaaagcg cgccaacgct gactccctgc ccttcctgct
    23341 tcggttgtat agtggattaa caaaaatcag gacaaggcga cgaagccgca gacagtacaa
    23401 atagtacgga accgattcac ttggtgcttc agcaccttag agaatcgttc tctttgagct
    23461 aaggcgaggc aacgccgtac tggtttaaat ttaatccact ataaagcacc tcctaccgca
    23521 agcccttttc atcaaatatg ccgtctgaaa cagaaaaatg cgtttcagac ggcatttttt
    23581 ccgtcaatac gaatccggaa tgtgtttgaa atacagcata aacagatacc aaaacagcat
    23641 cgcggcggct gcaccgagca gtacccatgc gctgatttcg gcgacttcgc gcagggcgcg
    23701 tttttgcctg cggctgaaaa ggcggttgat aatcaacgcg gcaagtgcga aaaagaaaaa
    23761 aatacggaaa agtctgccta tcatgtcggg aagcggtgga ggtcgtctga aaaagtatga
    23821 ttcgtgtgcg gcggatgagg gtcaaacgcg tccggctgct tgtccgaccg tgtcaaaaag
    23881 tcatgccgtt tgcgatataa taacgctttt cgccgcattt gttggaacag gatatgagtc
    23941 aaaatgcctc ggtgggcatt gtaatgcccc aaaaaattcc gtttgagatg ccgctggttt
    24001 tggaaaacgg taaaactttg ccgcgtttcg atctgatgat tgaaacctac ggcgagctga
    24061 atgctgaaaa aaacaatgcg gttttaatct gccacgcgct gtcgggcaac catcatgttg
    24121 cgggcaggca ttcggcggaa gataaatata cgggctggtg ggacaatatg gtcggacctg
    24181 gcaaaccgat tgatacggaa cgttttttcg tggtcggttt gaataatctg ggcggctgcg
    24241 acggcagcag cgggcctttg tcgattaatc ctgaaacggg cagggaatac ggcgcggatt
    24301 ttccggtggt tacggtgaag gactgggtaa aatcccaagc cgcgcttgcc gactatctcg
    24361 gtatcgaaca atgggcggcg attgtcggtg gcagcttggg cggcatgcag gctttgcagt
    24421 ggacgatttc ctaccccgag cgtgtgcgcc atgctttggt gattgcgtct gcgccgaaac
    24481 tgtccacgca aaatatcgcg tttaacgatg tggcgcgtca ggcaattttg accgaccctg
    24541 atttcaatga aggacattac cgcagccaca ataccgttcc tgcacggggc ttgcggattg
    24601 cccgcatgat gggacacatc acttatcttg ccgaagacgg tttaggcaaa aaattcggac
    24661 gcgatttgcg ttccaacggt tatcaatacg gctttggtgt tgaatttgaa gtggaatcct
    24721 atcttcgcta tcagggcgac aaattcgtcg gacggttcga cgccaacact tacctgctca
    24781 tgaccaaggc tttggactat ttcgatccgg cggcagattt cggcgacagc ctgacccgcg
    24841 ccctgcaaaa tgtgaaagcg aaattctttg tcgccagctt cagcaccgac tggcgtttcg
    24901 cacccgaacg ttcgcacgaa ctggtcaagg cactgattac cgcccaaaaa tccgtgcagt
    24961 atatcgaagt caaatccgca cacgggcacg atgccttttt aatggaagac gaagcctata
    25021 tgcgtgcggt cgccgcctat atgaacaacg tttataagga atgtcagcaa tgaacctgcg
    25081 cgacgattta cagttgattt acgaccggat acccgaaggc agccgcgtct tggacttggg
    25141 ctgcggcgac ggcgaactgc ttgccgcctt ggtcgaacac aaaaaatgca gcggctacgg
    25201 catcgaaatt gacaccgaca gcgtgattgc cgcgatgtcg cgcggcgtaa atgttatcca
    25261 agccgatttg gaagaaggtt taaccgcatt caacgatcaa agttttgatg tgattgtgtt
    25321 gagccaaacc atccaagcga tgcagaatac cgaaaaaatc ctgcgctgcc tgatgcgcgt
    25381 tgccaaacag gcgattgtca gcttcccgaa tttcggctac tggcgcaacc gcgtccaaat
    25441 cgcactcggc ggacatatgc cggtttccga acgtatgccc taccattggt acgacacgcc
    25501 caatatccat tggtgcacgc tcaaagactt tgatttgttg tgcgccaaaa acaacatccg
    25561 cgtcctcgaa cgcgccgtga tgacgggcaa cagacaggtc aaacatttcc ccaacctttt
    25621 gggcagcctt gcgttttacc gcgtcgggta agacaggttg agaaccttgt cggcaataac
    25681 aggttcttcg gttctattaa caacaggccg tctgaaaaat gaaatggcag gttttcagac
    25741 ggcctcttta atactggaaa caatagaatg aaaaacaaaa cctcatcact tctcttatgg
    25801 cttgccgcaa tcatgctgac cgcgtgttct ccgaacaaaa acgataaaac caaagaagtc
    25861 ggtgcatctg ctgcttcgtc ctccgcgtca tcagcttctt cccaatccga tttgcaaccg
    25921 gccgcatccg cccctgataa cgtcaagcag gcagaaagcg cgccgccgtc aaattgcacc
    25981 agcctgcacc ccgccaccgg cattgacgat ctcatgcagc aaatcgccga acacatcgac
    26041 tcggactgtc tgtttgccct ttcccatcac gaactggaaa cccgtttcgg cttacccggc
    26101 ggcggctatg acaacataca gcggctgctg tttcccgaca tccgccctga agatcccgac
    26161 taccatcaga aaatcatact ggcaattgaa gacttgcgtt acggaaagcg cacgatcagc
    26221 cggcaggcac aagatgcctt gatggaaccg gaacgccgcc tccgagaagc gacgctgttg
    26281 ctgatacagg gcagtcaaga aacccgcgga caaggcgagg agccgaaacg cacgcgttat
    26341 tttgaagttt cggcaacccc tgcctattcg agccggcaca acaacggact tggcggcaat
    26401 ttccaataca tcggccaatt gcccggctat ctgaaaatac acggagaaat gcttgaaaac
    26461 caatcactct tccggctgtc caaccgtgaa cgcaatcccg acaaaccgtt tttagacatc
    26521 cattttgacg aaaatggcaa aatcacacgt attgtcgttt acgaaaaaaa catctacttc
    26581 aatccaaact tggggcgaag ataaaaaaat gccgtctgaa acgttttcag acggcatttt
    26641 tcaatgcaac aaatcaagcg cgtttgcgga attcgccggt gcgggtatcg atttcgattt
    26701 tgtcgccgtt ttcgatgtaa gacatcactt ggatttcggt gcccccgacc aggcgcgcgg
    26761 ttttcatcac tttgcctgaa gtatcgcctt tgacggcagg ctcggtatac tcgacttcgc
    26821 gtacgatgat ggtaggcagt tcgacagaaa tggggttgcc ttcgtagaag gtaacttcgc
    26881 attggtcttc cataccgtca acgatgaatt tcaacgcgtc gccgatgttg tcagcttcga
    26941 tttcgtattg gttgaattct tcgtccataa agacgtacat cgggtcggca aagtagctgt
    27001 acgtacagtt tttgcgggac aggatgacca cgtcgaattt gtcgtcggct ttgtaaatgg
    27061 tttcggaagc cgcgccggtc agcaggtttt tcagtttcat gctgactttg gcggaagagc
    27121 ggccgccttt gatgtattcg gttttttgaa cgaccatagg atcgttgccg accataaata
    27181 cattgccggc gcgcagttct tgtgctgttt tcattgtgat tttccaatca aatcggttgt
    27241 cgtaaaacgc gctattctag cgtatttttt gatgctttga aacaaaggcg gcgagttttt
    27301 cggatgcgga aggctgcccg aaaagataac ggctccaatc ctccgcgcct tgccgccagc
    27361 cgttttgatg ttgttgcagg gtttgccaac attcgaggcg ttgcgtggcg gataaagcct
    27421 ctccgccgtt aaggtcgtct gaaaggcggc ggtgtgccga tgcggtttcg gacgtgtaga
    27481 aaccgtgtgc cttatcccaa aaggcgtgga gcttgtcgag atggacgttt tcatcttgcg
    27541 ggtagatgtg ccaaaagaag ggtttgcccg caagctgggc gcgcacgaaa ctgtcttcgc
    27601 cgcgaatgac ggcgcaatcg gcgaggtgca gcagtttgtc gaagtcctgt tgcggcacga
    27661 aagggatttt gacaaggcag acggatgccg tctgaaaaac atcgccgtcg ttttgcaggg
    27721 cattttgcgg aatgacgccg ctttgtttga ggctgtcgat gatttgcgtc cccgccagca
    27781 atagggtcat cgggctgcct gcctgttgcc acatttccag ccacttcgcc caaacatcgc
    27841 tccggtagcc gaaaagcagc cattcggggg cgtttttttc aggcagcatc agccgctgac
    27901 gcagggcttc ggtatcgaaa cggacggcat cacggtaatc gcgttcgcgt atcagcccgc
    27961 cgcttttttc gctgaaaccc ataaaccaaa aatatttttg aacaccctcc tgcggcgaag
    28021 gcatcaggtg cagcctttca ttgctttcct ccgcgctcaa atattcccaa ttcagccaaa
    28081 acggcttgtg tcggcggatg atgtgcagca cattttcggg caggtcgcag gcaaaagttt
    28141 cgatgacggc atcgggaaca ggcgcggtat caatatctgc cgcatcggaa tgccaagtgc
    28201 ggacatgaat atcctgatga acgcagggaa catcgggcaa atcagggcaa agcgcgcgca
    28261 aggcggacac atcgtccgtc cacaaatgca cctgccaacc gagttcgcgg tgcaaaacac
    28321 gggcaagccg ccacgaaacg ccgatgtcgc cgaaattgtc gatgaccttg caaaaaatcc
    28381 aacagacagg aaaagcgtat gtattcataa ccatctagaa aacaagctaa aatgcgccaa
    28441 aataatggaa caaatacaca accagcaaaa caatcggaat aaacagaaac atagtttgat
    28501 gtttcaaatc aaactcttgt ttcaaatgat gcttgatggt gtcgaaaagg acgaatttga
    28561 acagaaacgt cgcttcgcag gcaaggatga tgccgttaat cagatgctgg ggtttgtctt
    28621 cgggcggatt ggcggcgaaa acggcaagcg tcgccaaggg tatcaggcag acggcaagcc
    28681 agcggacaag caggtttcgg aacatcgcaa ggctttcaaa caaaaaaagc aaaacgccat
    28741 tatcgcccca agcacgcgcc ttgtctaacg gatgcgccga cgatgccgtc tgaagccttg
    28801 ccgcaggaaa acaccgcacc gccgaacctt taaatacgcc cgagacgggc gttccccgaa
    28861 aaatcggacg ctgccgccga tgcctgagga caaggctgca tcgggcgcgg gcatattgaa
    28921 aacccggcgc gtcggtttga aattttataa aggcatacgg taaacacgcc cccttgccgt
    28981 cggcgtgctt ccgcaaacca aaatataacg tcggcacgct ttccgctata atccgtattt
    29041 ttccaaacct gaaacgttat gccgaccccg aaagcctttg ccctgctcgg gccgaccgcc
    29101 ggaggcaaaa ccgcgctcgc cctcaaaatt gccgaaaccc tgcctgtcga aatcatcagc
    29161 ctcgattccg cgctggttta ccgcgatatg gacatcggca cggcgaaacc gtccgcctcc
    29221 gaacgcgcct ttgtcccgca ccaccttatc gacatcatcc cgcctaccga atcatacagc
    29281 gccgcccgct ttgtcgaaga ctgcacgcgc ttggtcgggg aaatttcctc acgcggcagg
    29341 tttgccctta ttgtcggcgg cacgatgatg tatttccgcg ccctgaccca aggtttgaac
    29401 gatttgcccg aagccgacgc ctgcctgcgt gccgacttgg acgaacaaaa acagatgtac
    29461 ggcttggatt tcctctaccg caccctgcaa aaagtcgacc ctgaaaccgc atgccgtctg
    29521 aaaccgaacg acagccagcg tatcggacgc gctttggaag tttattattt aaccggcaaa
    29581 ccgatgagca cacatctcgg cagcctgacc tcccatacgc tcccttttga tttgcatacc
    29641 gccgccctga ttcccgaaaa ccgcgcccgc ctgcatgaaa acatcgccct gcgtttccac
    29701 ctgatgcttg aacagggctt tatcggcgaa gtggaaaacc tgcgccgccg ctatcccagc
    29761 ctgaccgccg actcccccgc catccgctgc gtcggctacc gtcaggcatg gaaatatctg
    29821 gatggaaaaa ccgatttccc ggcatttgtc gagaaaggca ttgccgccac ccgccaactt
    29881 gccaaacgcc aactgacttg gttgcgcaaa acacctttag actgcgttgc cgacccgttt
    29941 tcagacggca cttcatgcac acgcctgatt gaggcggcaa aacggttttt cggcgcataa
    30001 accatgctga ccacaccgcc gctcgccccc aaaaccgtcg ccgccctgca caggctcggt
    30061 atccgtacgc tcgaagaact gcggcaaaac ggttcggtca aagcctttct gctgctcaaa
    30121 gcatcgggtt tgaccctcac gaaaagcacg ctgtggcaac tcgagtcgct gctggacggc
    30181 acgccgccgc aagaaatgtc ccaagcgcat aaagctcgcc tgcttgccga attgaaaaac
    30241 catccgcccg tcgccgcctt tccgccgcag gaagaaatgg aacacttcat gcgcgaagca
    30301 ctgcgccaag cagaacaatc cgccgccgac ggcgaaatac ccgtcggggc agtcatcgtt
    30361 tcagacggca aaatcatcgc ggcggcacac aacacctgca ttgccgactg caatgtcagc
    30421 cgccacgccg aaatcaacgc cctggcacag gcaggcagcg aaatgcaaaa ctaccgcctt
    30481 gacggatgcg acatctacat caccctcgaa ccctgcgcca tgtgcgcgtc cgcactgata
    30541 caggcacgaa tcaggcgcgt gatctacggt gcggcagaac ccaaaaccgg cgcggcagga
    30601 agcatcgtca acctgtttgc cgacaaacgc ctcaatacgc acaccgccat acggggcgga
    30661 atcctgcaag aagaatgccg cgccgtatta agccgttttt tccaaaacaa aagaaaaggt
    30721 tgaacctatg accgccttgc tcgtcatcct cgccctcgcc ctgatagccg ccggtacggc
    30781 gggcatcgtt taccccgccc tgcccggatt ggcattgatg tttgccggaa cctggctgct
    30841 cgcctactcc ggcggctacc aaatctacgg cgcgggcgtt ttgtggacgg tcggactcat
    30901 cagccttgcc ggcatactgg cggactatgt ggcaggcata tgggggacaa aatataccgg
    30961 agcgggcaag ctcgccgttc gcggcgcatt ggtcggcagc atcatcggca tatttttctc
    31021 ccttcccgga ctaatactcg gtccctttat cggcgcggcg gcaggcgaac tgatcgatcg
    31081 gcgcaatatg cttcaggcag gtaaagcggg cttgggtacg ctgttggggc ttatcgtcgg
    31141 tacgacattc aaaatcggct gcgccgtatc catcttgttt atcctgttgg tgaaatacat
    31201 cgcctacctg ttttaacccc ttcagacggc ataccggcaa attgctataa tgccgtctga
    31261 acccttttca caaagcacca tatggcaaac caaagaccta tctacggctt ccatgccgtc
    31321 aacgcccgat tgtggcaaaa ccccaaatcc atcgtcgaac tctatgtcca agaaggcaaa
    31381 aacgatgtac gcacgcgcga agtgttggaa aaggcggcaa acgaaaacat ccgcgtatat
    31441 tttgccgatg ccgaccgcct caacgccatc agcaaaggtg cgcgccatca gggcgtggtc
    31501 ggatttatcg atgcctccaa aaaccacgtc cacctcgaag acgtattgga aaacttaagc
    31561 gaaccgccgc tgctgctgat actcgacggc atcaccgatc cgcacaacct cggcgcgtgc
    31621 ctgcgtaccg ccgacgcaat gggcgtacat gccgtcatcg caccgaaaga caaaagcgcg
    31681 gggctgaacg ccaccgtcag caaagtcgcc agcggcgcgg cggaaaccgt cccctacatc
    31741 accgtaacca acctcgcccg caccctgcgc gagctgaaag aatacggcat ttggatcatc
    31801 ggcaccgata tgggcggcaa cgccgacctt taccattgcg atctgcccga cagcgcggca
    31861 tgggtgatgg gcaacgaagg cgacggtatg cgccgcctga cacgcgaaca ttgcgacatg
    31921 ctggtgtcca tacccatgtt cggcacggtc gaaagcatga acgtctccgt gtctgccgga
    31981 atggtattaa gcgaaacccg ccggcagcgc gtattaaaaa acgaaaaagc gtaagcctca
    32041 aaaacaatgc cgtctgaaac agggattctg tttcagacgg cattcgtttt caaaatcagt
    32101 gttccaagtg gtcggtatca aacttgaccg ccgcctcggt tttatcttcg ggcaagacca
    32161 aattcagcaa gactgccgta atgccgccgg cggaaataga gttttggaac aagacaggca
    32221 ggtttttaaa cacttccggc tcaaacgcca cgcccaagcc caagccgacc gaagtcgccg
    32281 caatcaccgc ctcgcgcctg cggatgccgt ggctgaccaa aatccgcaca cccgcaatcg
    32341 caatcaagcc gaacatcaaa accatcgcgc cgcctaaaac cggactcgga atcgtcgtaa
    32401 acgcgcgtcc gacaacgggg gaacagaccc aacagcacca aaatcacggc aatatatttg
    32461 cccacatggc gcgaagccac gccggtcatc tgaatcacgc cgttgttttg cgcaaacgtt
    32521 gtcagcggca gcgaacccaa agccgtcgca atcaccgaca ccaagccgtc tgccaacacg
    32581 ccgccgcgca ggcgtttggt gtattcctcg ccttcaatcg gctgatcgga caccattgcc
    32641 gttgcggtca aatcgccgac cgcctcaaac acgctcaaca ggaaaatcgc acccgccaca
    32701 ataaatgcgt gccagtcaaa agcaaaacca tatttaaacg gtacgggcag cgtaaccagc
    32761 ggcaggtttt gcagtgccga aaaatccacc ttgcccaaaa acagcgcgac gatatagccg
    32821 gcaatcagac cgaccgcaat gccgctcatc cgcagcagcg ggtttttcat gcagttgaac
    32881 accagcacaa tcagcagcac cagcgatgcc agccccaagt tttccatcga gccgaacgtg
    32941 ccgtccgcct ttgcgccgaa gccgccgccg aaatcggtaa taccgacgtg taccaaactc
    33001 aagccgatca gcatcaccac cacaccgctg accgtcggcg taatcacttt tttcaaatac
    33061 ggcagaagcc acgccgagaa acacaccaaa aacgcgccga caaacgatac gcccaagagc
    33121 gtcgaaatca tcgcatcctt agtcaaaccg ccctctttca tccccgcgcc cagcgcaatc
    33181 atgacggtaa cgaacgagaa attcaccgac tggatagaca gcatccccga accgaccggc
    33241 ccgaagcggt tgacctgcaa ataagtgccg acacccgacg caaccatcgc catcgacacg
    33301 agatacgccg tcatctccac cggcagttcc agcgcgccgc ccacaatcag cgcgggcgta
    33361 atcatcggca cgaaaatcgc caaaagatgg gtaaccgcgc tcaacagcgc attaccgaac
    33421 ggcggcctat cctccaaacc gtacaccaaa tcaggcgcat ccgccccttt tcccatatga
    33481 ccgctcataa tgtttccttg cttcaaatat tgaaaaaacc aaagcgcgga ttgtagcgaa
    33541 tccgccatac cgcttcaatt tcgatttcgg acggcatacg cgcccgtccg gcaaacagat
    33601 tccgaaccgt cgccgccgga atatcgtttg caaaacgcaa taacctgatt tcaaacacaa
    33661 aaatacaaac ccgacgcatc cgccgccaag ccgccccgtg cataccggac ccgccggatt
    33721 tcacacctgc ggtaaagtag gctacaatcg gaagcattac cgccccctac accacaactg
    33781 ataaaaggtt ctgtatgtta caaggtagcc tggttgccct gattaccccg atgaatcaag
    33841 acggcagcat ccattacgaa caactccgcg acttaatcga ctggcacatt gaaaacggca
    33901 cggacggcat cgtcgccgtc ggcacgacag gcgaatccgc caccctctcc gtcgaagaac
    33961 acaccgccgt tatcgaagcc gtcgtcaaac acgttgccaa acgcgtcccc gtcatcgccg
    34021 gcacaggggc gaacaacacc gtcgaagcca tcgccctttc ccaagccgcc gaaaaagccg
    34081 gcgcggacta caccttatcc gtcgtcccct attacaataa gccctcccaa gaaggcattt
    34141 accgccattt caaagccgtt gccgaagccg ccgcgattcc gatgattatc tacaacgtgc
    34201 ccggccgtac cgtcgtcagc atgactaacg acactatcct gcgccttgcc gaaatcccca
    34261 acatcgtcgg cgtgaaagaa gccagcggca acatcggcag caacatcgaa ctcatcaacc
    34321 gcgcgcccga aggcttcgtc gtcctgtccg gcgacgacca caccgcccta ccgttcatgc
    34381 tctgcggcgg acacggcgtt attaccgtag ccgccaacgc cgcgcccaag ctctttgccg
    34441 atatgtgccg cgccgcgctt caaggcgata tcgcccttgc acgcgaactc aacgaccggc
    34501 tgattccgat ttacgacacc atgttctgcg aacccagccc cgccgcaccg aaatgggcgg
    34561 tatccgccct gggcagatgc gaaccgcacg tccgcctgcc gctcgttccg ctgacggaag
    34621 gcggacaggc aaaagtccgc gccgccctga aagcctcagg acaactctaa atataactat
    34681 gccgtctgaa ccgttcggac ggcataacgc aacaaacact ttaatatcca tcacacagga
    34741 tgacacgatg acccatatca aacccgtcat tgccgcgctc gcactcatcg ggcttgccgc
    34801 ctgctccggc agcaaaaccg aacagcccaa gctcgactac caaagccggt cgcaccgcct
    34861 gatcaaactt gaagtcccac ccgatttgaa caaccccgac caaggcagcc tctaccgcct
    34921 gcctgccggt tcgggcgccg tccgcgccag cgatttggaa aaacgccgca cacccgccgt
    34981 ccaacagcct gccgatgccg aagtattgaa aagcgtcaaa ggtgtccgcc tcgagcgcga
    35041 cggcagccaa cgttggcttg tcgttgacgg caaatcccct gccgaaatct ggccgcttct
    35101 gaaagccttt tggcaggaaa acggcttcga catcaaatcc gaagaacccg ccatcggaca
    35161 aatggaaacc gagtgggcgg aaaaccgtgc caaaatcccc caagacagct tgcgccgcct
    35221 attcgacaca gtcggtttgg gcggcatcta ctccaccggc gagcgcgaca aattcatcgt
    35281 ccgtatcgaa cagggcaaaa acggcgtttc cgacatcttc ttcgcccaca aagccatgaa
    35341 agaagtgtac ggcggcaaag acaaagacac gaccgtatgg cagccctccc cgtccgatcc
    35401 caacctcgaa gccgctttcc tgacgcgctt tatgcaatat ttgggcgttg acggacagca
    35461 ggcggaaaac gcatcggcaa aaaaacctac ccttcccgcc gccaacgaaa tggcgcgtat
    35521 cgaaggcaaa agcctgattg tctttggcga ctacggcaga aactggcggc gcaccgtgct
    35581 cgccctcgac cgcatcgggc tgaccgtcgt cggtcaaaac accgaacgcc acgctttcct
    35641 ggttcaaaaa gccccgaacg aaagcaatgc agttaccgaa caaaaacccg gcctgttcaa
    35701 acgcctgctg ggcaaaggca aagcggagaa acctgccgaa cagccggaac tgattgtcta
    35761 tgccgagcct gtcgccaacg gctcgcgcat cgtcctgctc aacaaagacg gcagcgcata
    35821 tgccggcaaa gacgcatccg cattattggg caaactccat tccgaactgc gttaaaccat
    35881 tcaaaacaaa agcagcttcc aaacagaagc tgctttttta tgcggaactt tttacaacaa
    35941 atggggcaaa atatcctcaa ctgcctgaac caacgcatcc accaaaggcg gatcgaacgc
    36001 acgatgccct gcctgaacca ccctcaattc cgcttcggga aaggctttcg acagcgccca
    36061 cgcactctgc atcggcgtac acaaatcata ccgcccctgc acgataatgg tcgggatatg
    36121 ccgtattttg ccgatattgt tcaaaatcgc cctatcgccc tgcaaccagc cgccgttgac
    36181 aaaataatgg ttttccaaac gcgcgattgc cagcgaggca taagcatctt catccacttc
    36241 ctccggctcg aaacggatca gatagctttc ccaatccgcc caagcctttg cggcagacag
    36301 gcacacttct tcatcttgat gaaacagcaa cccgtgatac gcctcaatca gccggttccg
    36361 ccgattttca gcaatcggcg cgacaaattt ttgccattgt tccggataaa tccggctcac
    36421 accgcccgcc tcgttcagcc acgccgtttc agacggcctg cacaaaaata tcccgcgcaa
    36481 taccaatccc tttacccgtt caggatgggt ttgggcataa gccagcgaca aagtgctgcc
    36541 ccacgaaccg ccgaacacca gccatttcct gatacccagc atttcacgga ctttttcaat
    36601 atccgccacc aaatcccaag tcgtattgtc ttccgcacaa gcatacgggc gcgaacgtcc
    36661 gcaaccgcgc tggtcgatga tgacgatacg gaacacatcg ggattgaaaa aaccccgaca
    36721 ttcaggcgaa gcccccgcgc ccggcccgcc atgtaaaaaa ataaccggca caccgtcggg
    36781 attgcccgat tcctcccaat aaatttgatg aatttcagac acctgcaagt atccgctatg
    36841 aaaaggctgt tttatctcat acatcatctt ctcccatatt gcttctgaca atccgaacat
    36901 tcccacacgc aacatcacgc acgagacaca agccgccccg aaaggcaaat gccgaaaaat
    36961 cgcgatatag tgaattaaca aaaatcagga caaggcggcg agccgcagac agtacggata
    37021 gtacggaacc gattcactcg tgcttaagca ccttagagaa tcattctctt tgagctaagg
    37081 cgaggcaacg ccgtaccggt ttttgttcat ccactataac agcaaccctg tcgccgtcat
    37141 tcccgcaaaa gcgggaatcc agtccgttca atttcggtca tttccgataa attcctgctg
    37201 cttttcattt ctagattccc actttcgtgg gaatgacggc ggaagggttt tggttttttc
    37261 cgataaattc ttgaggcatt gaaattccag attcccgcct gcgcgggaat gacaattcat
    37321 aagtttcccg aaattccaac ataaccgaaa cctgacaata accgtagcaa ctgaaccgtc
    37381 attcccacca cttttcgtca ttcccgcgaa agcgggaatc cagaatctc
//
LOCUS       DAXISH010000013        33876 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.013, whole genome shotgun sequence.
ACCESSION   DAXISH010000013 DAXISH010000000
VERSION     DAXISH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 33876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33876
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.013"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..744
                     /locus_tag="ACFOV4_000671"
     CDS             <1..744
                     /locus_tag="ACFOV4_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7618738.1"
                     /translation="KLGVKTGLSIDKNRLPYLDEYYKTTKPAGTLFEPDYEALNAYKP
                     QLIIIGSRAAKAFDKLNEIAPTIEMTADTANLKESAKERIDALAQIFGKQAEADKLKA
                     EIDASFEAAKTAAQGKGKGLVILVNGGKMSAFGPSSRLGGWLHKDIGVPAVDEAIKEG
                     SHGQPVSFEYLKEKNPDWLFVLDRSAAIGEEGQAAKDVLDNPLVAETTAWKKGQVVYL
                     VPETYLAAGGAQELLNASKQVADAFNAAK"
     gene            762..911
                     /locus_tag="ACFOV4_000672"
     CDS             762..911
                     /locus_tag="ACFOV4_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618739.1"
                     /translation="MPSETRMQTASCVSDGIARYGGFKQGFPLRRFGLPCLNLLRRNA
                     FPFCL"
     gene            908..1876
                     /locus_tag="ACFOV4_000673"
     CDS             908..1876
                     /locus_tag="ACFOV4_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFC7618740.1"
                     /translation="MTAKPFSLNLTNLLLLAVLFAVSLSVGVADFRWSDVFSLSDSQQ
                     VMFISRLPRTFAIVLTGASMAVAGMIMQILMRNRFVEPSMAGASQSAALGLLLMSLLL
                     PAAPLPVKMSVAAVAALIGMLVFMMLIRRLPPTAQLMVPLVGIIFGGVVEAVATFIAY
                     ENEMLQMLGVWQQGDFSSVLLGRYELLWITGGLAVFAYLIADRLTILGLGETVSVNLG
                     LNRTAVLWSGLIIVALITSLVIVTVGNIPFIGLVVPNIISRLIGDRLRQSLPAVALLG
                     ASLVLLCDILGRVIVFPFEIPVSTVFGVLGTALFLWLLLRKPAHAV"
     gene            1866..2840
                     /locus_tag="ACFOV4_000674"
     CDS             1866..2840
                     /locus_tag="ACFOV4_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFC7618741.1"
                     /translation="MPSEKNIGFMAGSSRPLWVAFALLLVSCVLFMTLNVKGDWDFVL
                     HLRLTKLAALLMVAYAVGVSTQLFQTLTNNPILTPSILGFDSLYVFLQTLLVFTFGGV
                     GYASLPLTGKFGFELAVMMGGSLLLFYTLIRQGGRDLPRMILIGVIFGILFRSLSSLL
                     SRMIDPEEFTAAQANMFAGFNTVHSELLGIGALILLVSAAVVWRERYRLDVHLLGRDQ
                     AVNLGISYTRNTLWILLWIAALVATATAVVGPVSFFGLLAASLANHFSPSVRHSVRLP
                     MTVCVGGILLVGGQTVFEHFLGMKAVLSVVVEFAGGLVFLYLVLKHKK"
     gene            2885..3511
                     /locus_tag="ACFOV4_000675"
     CDS             2885..3511
                     /locus_tag="ACFOV4_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HFC7618742.1"
                     /translation="MTQERLPEFFDRAPTLTVQDPLAAFLGAAENGILTYRYADAVRL
                     CGHSCPTVAGAYLMVIKGLKALYGEELPERGGIEAFMQGARDEGTVGVTASVVQLLTG
                     AAPETGFGGVGPAGRFARRNLLSFGAGEINGTLALRRRDTGKTVAVSLNAALQPFAPE
                     MRELMPKTVGGSASAEELERFGQLWQARIKAFLTESADDPQFVIVREV"
     gene            3595..4353
                     /locus_tag="ACFOV4_000676"
     CDS             3595..4353
                     /locus_tag="ACFOV4_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC7618743.1"
                     /translation="MITIRNVSYRIGTRPILDNVSLDIPEGGITALVGPNGAGKSTLF
                     SFMARLRPLESGSIAYRGKNLACTPTAELAKTLSILTQENSIMSRITVRDLLMFGRYP
                     YHQGRPTAECRRIVNGAIEEFHLQDFADRYLTELSGGQRQRAMIAMVFCQRTDYVLLD
                     EPLNNLDMYHARSLMQILRRLTDEHKRTTVVVLHDINQAAAYADHVVAMKNGQVAMQG
                     KPDDIFTAANIKTLFDMDVSVLDHQSKKLIVHHI"
     gene            complement(4412..4750)
                     /locus_tag="ACFOV4_000677"
     CDS             complement(4412..4750)
                     /locus_tag="ACFOV4_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFC7618744.1"
                     /translation="MKKIEAIVKPFKLDDVREALTEIGITGMTVSEVKGFGRQKGHTE
                     IYRGAEYAVDFLPKVKIELVLADDAVERAIDVIVEVARSGKIGDGKIFVLPVEEAIRI
                     RTGERADAAV"
     gene            4845..5057
                     /locus_tag="ACFOV4_000678"
     CDS             4845..5057
                     /locus_tag="ACFOV4_000678"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618745.1"
                     /translation="MPETVIPAQAGIPISAFQQYLKVSVNPNFHIPNRTETTAFDLKT
                     YGSSCPPLYFLQLSAYPALGKNQKNR"
     gene            5214..9176
                     /gene="purL"
                     /locus_tag="ACFOV4_000679"
     CDS             5214..9176
                     /gene="purL"
                     /locus_tag="ACFOV4_000679"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HFC7618746.1"
                     /translation="MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFAG
                     SEKALDAATVEKLQALLAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENC
                     GLAGIERIERGMAVWLEGRLNDDEKQQWAALLHDRMTESVLPDFQTASKLFHHLESET
                     FSTVDVLGGGKEALVKANTEMGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSE
                     HCRHKIFNADFILNGEKQPKSLFGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYP
                     DAAENQGYRFHEEDTHIIMKVETHNHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKA
                     GLTGFTVSNLNIPCLKQPWEQDYGKPEHISSPLDIMIEGPIGGAAFNNEFGRPNLLGY
                     FRTFEEKFDGQVRGYHKPIMIAGGLGSIQAQQTHKDEIPEGALLIQLGGPGMLIGLGG
                     GAASSMDTGTNDASLDFNSVQRGNPEIERRAQEVIDRCWQLGGKNPIISIHDVGAGGL
                     SNAFPELVNDAGRGAVFKLREVPLEEHGLTPLQIWCNESQERYVLSILEKDLDTFRAI
                     CERERCPFAVVGTATDDGHLKVRDDLFANNPVDLPLNVLLGKPPKTTRTDKTVTPSKK
                     PFHADDIDITEAAYRVLRLPAVAAKNFLITIGDRSVGGMTHRDQMVGKYQTPVADCAV
                     TMMGFNTYRGEAMSMGEKPTVALFDAPASGRMCVGEAITNIAAINIGDIGNIKLSANW
                     MAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSMKTVWQDGEEKKSVVSPLS
                     LIISAFAPVQDVRKTVTPELKNVEDSVLLFVDLGFGKARMGGSAFGQVYNNMSGDAPD
                     LDDTGRLKAFYNVIQQLVAEDKLLAYHDRSDGGLFAVLVEMAFAGRCGLDIDLNLLLA
                     QTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEELGAVIQVRKQDVADIINLFYQ
                     QQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTWQETSHQIQRLRDNPACAD
                     SEFALIGDNDRSALFANLKFDVNEDIAAPFINSGAKPKIAILREQGVNGQIEMAAAFT
                     RAGFDAYDVHMSDLMAGRFRLADFKMLAACGGFSYGDVLGAGEGWAKSILFHPALRDQ
                     FAAFFADPDTLTLGVCNGCQMVSNLAEIIPGAEAWPKFKRNLSEQFEARLSMVHVPKS
                     ASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQYVDGQNQVTQTYPLNP
                     NGSPQGIAGITNADGRVTIMMPHPERVYRAAQMSWKPEGWTELSGWYRLFAGARKALG
                     "
     gene            9271..10029
                     /gene="gloB"
                     /locus_tag="ACFOV4_000680"
     CDS             9271..10029
                     /gene="gloB"
                     /locus_tag="ACFOV4_000680"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003678284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004416 - hydroxyacylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019243 - methylglyoxal catabolic process
                     to D-lactate via S-lactoyl-glutathione [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HFC7618747.1"
                     /translation="MKITPVKALTDNYIWMIQHGNHAVCVDPSEPSPVLEFLVRNRLM
                     LAQTWVTHPHPDHEGGAAALWRGYMESPVYGESDIEAATHTVTAGTQFTFGDGQVTVW
                     ATPGHTDRHTSYLLETSDGIHVFCGDTLFSAGCGRVFTGTIEQLYDSFQRFNRLPENT
                     LFYPAHEYTAANLDFAAHIEPDNADIQTALKAAAHTPTLPVTLARERRVNPFLRVDLP
                     HVRDRAEALSGKTLNSSLDTFVALRELKNQYRTK"
     gene            10343..14816
                     /locus_tag="ACFOV4_000681"
                     /pseudo
     CDS             10343..14816
                     /locus_tag="ACFOV4_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003678286.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S6 family peptidase"
     gene            15048..16502
                     /gene="mgtE"
                     /locus_tag="ACFOV4_000682"
     CDS             15048..16502
                     /gene="mgtE"
                     /locus_tag="ACFOV4_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFC7618748.1"
                     /translation="MSIEPTPPNLENDGIENDVERVSADFDRVHSLCEILEPAFEQIE
                     NGTPLEDAPLRDKLTELTVLLSELHPADVAAVLESLPPRERNIVWILVKPEDDGEVLL
                     EVSDAVRETLIESMDKDELLAAVDDLDADELAELADDLPHQVVYEALQTRDEEERAQV
                     KAAMSYEDNQVGAIMDFELVSIRADVACEVVLRYLRRFDSLPDHTDKIFVVDENDVLQ
                     GVLPIRKLLVADPEDLVENVMAKDVVRFRAEDDVEEAAQAFERYDLVTAPVVDENKKL
                     IGRITVDEMVDVIREESEADMLNMAGLQEEEDLFAPVLDSVKNRWMWLAVNLCTAFLA
                     SRVIGAFESSIEKIVALAALMPIVAGIGGNSGNQTITMIVRAMAMGQLTDMQAGRLLK
                     KEVSVALVNGIIWGAVMGAVSWLLYGSLGIGLVMIAAMTLNLLLAATVGVLIPVVMEK
                     FGRDPALGSSVLITAVTDSGGFLIFLGLATLFLL"
     gene            complement(16588..17496)
                     /gene="hslO"
                     /locus_tag="ACFOV4_000683"
     CDS             complement(16588..17496)
                     /gene="hslO"
                     /locus_tag="ACFOV4_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFC7618749.1"
                     /translation="MNQTAINRADVRTRFIFDDMPVRGLHVRLENVWQHIVKQKNYPA
                     AIRRALGELLAAGVLLSGNLKNEGTLIVQVQGQGRLKMLVAEATSDRTVRATARWDEA
                     AEIGEDESLVDLLGEGGVFVLTLQPKDGEPWQGVVPLEGDGIAQMLMNYMKRSEQLDT
                     HIVLSASDEAAGGLLVQRLPEEVLDEEAWEHVSTLARTLTAEELAELDAQHVLYRLFH
                     ETPPRVFEPETFEFSCTCSRGKVSDMLLMLGGEEVGGVVVEQGSIEVDCDFCHSKYVF
                     DETDVNVLFGEDVVGVAKGLPRHTVQ"
     gene            17741..18496
                     /locus_tag="ACFOV4_000684"
     CDS             17741..18496
                     /locus_tag="ACFOV4_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFC7618750.1"
                     /translation="MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAED
                     EQPVLPINRAPARRAGNADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLN
                     EQPVLPVNRAPARRAGNADELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAM
                     GINLPRTSAEQARMGTPVARSELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTG
                     KNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN"
     gene            18515..18733
                     /locus_tag="ACFOV4_000685"
     CDS             18515..18733
                     /locus_tag="ACFOV4_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618751.1"
                     /translation="MSMPEMPKWYDDDGQIVSCTEKVKVMSENMAELYQTAQDAFEDA
                     LLMGCGERQLRDYLLALIEGLENPYRKV"
     gene            18878..19222
                     /locus_tag="ACFOV4_000686"
     CDS             18878..19222
                     /locus_tag="ACFOV4_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFC7618752.1"
                     /translation="MNIIRALLIILGCLATGETAVFLAGIKLPGSIVGMGVLFALLQA
                     GWVKTSWLQQLTDALMANLTLFLVPPCVAVISYLDLIADDWFSILVSASASTLCVLLI
                     TGKVHRWIRSII"
     gene            19222..19914
                     /locus_tag="ACFOV4_000687"
     CDS             19222..19914
                     /locus_tag="ACFOV4_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFC7618753.1"
                     /translation="MNEILRQPSVLLFLTLAVYALAIIVRTRTGNIFCNPVLVSTVVL
                     IAYLKILGIDYAVYHNAAQFIDFWLKPAVVVLAVPLYQNRRKIFNQWLPVIVSQLAGS
                     VTGIVTGMYFAKWLGAEREVVLSLASKSVTNPIAIEITRSIGGIPAITAATVIIAGLV
                     GQIAGYKMLKNTVVMPSSVGMSLGTASHAMGIAASLERSRRMAAYAGLGLTFNGVLTA
                     LIAPLLIPVLGF"
     gene            19981..21201
                     /gene="argJ"
                     /locus_tag="ACFOV4_000688"
     CDS             19981..21201
                     /gene="argJ"
                     /locus_tag="ACFOV4_000688"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HFC7618754.1"
                     /translation="MAVNLTEKTAEQLPDIDGIALYTAQAGVKKPGHTDLTLIAVAAG
                     STVGAVFTTNRFCAAPVHIAKSHLFDEDGVRALIINTGNANAGTGAQGRIDALAVCAA
                     AARQIGCKPNQVLPFSTGVILEPLPADKIIAALPKMQPAFWNEAARAIMTTDTVPKAA
                     SREGKVGDKHTVRATGIAKGSGMIHPNMATMLGFIATDAKVSQPVLQLMTQEIADETF
                     NTITVDGDTSTNDSFVIIATGKNSQSEIDNIADPRYAQLKELLCSLALELAQAIVRDG
                     EGATKFITVRVENAKTRDEARQAAYAVARSPLVKTAFFASDPNLGRLLAAIGYAGVVD
                     LDTDLVEMYLDDILVAEHGGRAASYTEAQGQAVMSKAEITVRIKLHRGQSAATVYTCD
                     LSHGYVSINADYRS"
     gene            21261..22663
                     /locus_tag="ACFOV4_000689"
                     /pseudo
     CDS             21261..22663
                     /locus_tag="ACFOV4_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            22852..24243
                     /gene="hrpA"
                     /locus_tag="ACFOV4_000690"
     CDS             22852..24243
                     /gene="hrpA"
                     /locus_tag="ACFOV4_000690"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HFC7618755.1"
                     /translation="MFPDFSQTLSKDRHFLQSAFKNPNKYGGLSKVEEKYRKSHEIFL
                     RRLAALPKPEFDNTLPVHEKLEEIKKTVAEHQVTIICGETGSGKTTQLPKICLELGRG
                     AAGLIGHTQPRRLAARSVAERIAEELKSEIGSAVGYKVRFTDHTSRDACVKLMTDGIL
                     LAETQTDRYLAAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDAER
                     FSRHFNGAPVLEVSGRTYPVEILYRPLTGKDEDDAEVELTDAIVDAADELARHGEGDI
                     LVFLPGEREIREAAEALRKSTLRRNDEILPLFARLSHAEQHKIFHPSGAKRRIVLATN
                     VAETSLTVPGIKYVIDTGLARVKRYSARAKVEQLHIEKISQAAARQRSGRCGRVSAGV
                     CIRLFSEEDFNSRPEFTDPEIVRSNLAAVILRMASLKLGDVAAFPFLEMPDSRYINDG
                     FQVLLELGAVEAA"
     gene            24344..25471
                     /locus_tag="ACFOV4_000691"
     CDS             24344..25471
                     /locus_tag="ACFOV4_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HFC7618756.1"
                     /translation="MKHLLIDFENVQPQNLDKLLTENTHIWLFIGVLHKMLPISLVQS
                     LLRFGERVHLVQLQKTGKNALDFYLSYYLGQITATDPNAQIGILSRDGGYDVLVEHIL
                     KNHQAKGIVRLANIDEVQHQKITTEPPSALLENTPQPETTLKPQQPLTSYFQAALTAL
                     RRPDAFRPCRLHNLRQNLRKHILSDLFKEKTDEECEITTANVINKLKAQNFISIDEQE
                     TVSYHLSDNDLLQRIQRHILSQRPKTYADFQAVVQNRADALHLTVGTNDIQSFARHLR
                     DQNLIRQNNGKIEYAPFTEPKPQPTPKQPKKTAWEPDEIIWKKVIAALSLKNRPNKTK
                     TLRNTIQALTKSNAQETDKLLQHLQGTQVLRIDGTKIVYIK"
     gene            25648..27225
                     /gene="lpt3"
                     /locus_tag="ACFOV4_000692"
     CDS             25648..27225
                     /gene="lpt3"
                     /locus_tag="ACFOV4_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipooligosaccharide phosphoethanolamine
                     transferase"
                     /protein_id="HFC7618757.1"
                     /translation="MMKKSLFVLFLYSSLLTASEIAYRFVFGIETLPAAKMAETFALT
                     FVIAALYLFARYKTSRLLIALFFAFSIIANNVHYAVYQSWMTGINYWLMLKEVTEVGS
                     AGASMLDKLWLPALWGVLEVMLFCSLAKFRRKTHFSADILFAFLMLMIFVRSFDTKQE
                     HGISPKPTYSRIKANYFSFGYFVGRVLPYQLFDLSRIPAFKQPAPSKIRQGSVQNIVL
                     IMGESESAAHLKLFGYGRETSPFLTRLSQADFKPIVKQSYSAGFMTAVSLPSFFNAIP
                     HANGLEQISGGDTNMFRLAKEQGYETYFYSAQAENQMAILNLIGKKWIDHLIQPTQLG
                     YGNGDNMPDEKLLPLFDKINLQQGKHFIVLHQRGSHAPYGALLQPQDKVFGEADIVDK
                     YDNTIHKTDQMIQTVFEQLQKQPDGNWLFAYTSDHGQYVRQDIYNQGTVQPDSYLVPL
                     VLYSPDKAVQQAANQAFAPCEIAFHQQLSTFLIHTLGYDMPVSGCREGSVTGNLITGD
                     AGSLNIRDGKAEYVYPQ"
     gene            27327..30407
                     /locus_tag="ACFOV4_000693"
     CDS             27327..30407
                     /locus_tag="ACFOV4_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3418 domain-containing protein"
                     /protein_id="HFC7618758.1"
                     /translation="MDARSNPVNVSDGLQNSSGHIGTNTRYRLTKLGEQMARLPIDPK
                     IARILLAAKKHDCMAEILVIASALSIQDPRERPLEARDAAAKAHERFTDKQSDFLAYL
                     NIWDSFQRERDKGLSNKQLVQWCRQYFLSHLRMREWRELHHQLAQTAIEMGLTTKEAA
                     FRRPPEIRQLTSSESQGDQDLAAKLKQKQLDKKQHRAQIRAAKEAGYEQIHRALLTGL
                     IANVGMKSPDGNDYTGARGSRFHLFPASALFKAKPKWVMAAELVETTRLYARDVAVIQ
                     PEWIEQEAPHLVRYHYFEPHWEQKRGEVVASERVTLYGLTVLPRRPVPYGKVAPEEAR
                     EIFIRSALVAQECDLKADFFVHNKKLIKEITELEHKSRKQDVLVDDEALFAFYHERLP
                     NFYTADAVSDDLHPTNPQQTAPSPVGEGWGEGKTVAAQTNFSATAANPLPNPLPQERE
                     QSAAASAVSNDLHPANPQQTAPSPVGEGWGEGKTVAAQTNFSATAANPLPQEGEQSAA
                     ASALSDDPQPQKQPASQKGRLKPLPLADIRTFQAWLKTAERENPRLLFLSRDDLMQHA
                     AAHITEEQFPKFWQTADGKFKLSYRFEPHHPLDGVTLTLPLTVLNRISPAALEWLVPG
                     MLREKIQLLIKALPKQIRRICVPVPDFITKFLESNPDRQAAIIPQLAHFIAKSAGDMR
                     IFEQIDQDAWAVQELPEHCYLNLRIIDDGGQELAGGRKLHELQQQLGQAAATTFRDNT
                     QEFERDNVTAWDIGTLPESIKFARGKQQLTGYLGLQKEKDGRIALRLCDTIEAAEQAH
                     RQGVIELMKLQLKEQVKDLNKGIQGFTQAAMLLKHINADTLRDDLTQAVCDRAFIGED
                     ELPRNEKAFKEQIKRARSRLPAVKEALSRYLQETAAAYAELNGKLGKHPLTHLLRLRL
                     QTLLAPSFATRTPWAQWPRLPIYLKAMTLRLEKYSSNPARDAAREADIQELEQMWQEK
                     TDSLVKQGLPISDGLAGFKWMIEELRVSLFAQELKTPYPVSVKRLMKEWERLNK"
     gene            30466..32073
                     /locus_tag="ACFOV4_000694"
     CDS             30466..32073
                     /locus_tag="ACFOV4_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003758255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFC7618759.1"
                     /translation="MKSENNYERIVQNSKKFQHSQKNEMQKRITDLLQQLTNGIHERD
                     QIMAVSLLGAIAGHNTFLFGPPGTAKSLISRRLACAFENPQYFEYLMNRFSTPEEVFG
                     PVSIKALKEDRYLRKIEGYLPTADFAFLDEIWKSSPAILNNLLTIINEHIFKNGDERF
                     NVPLKALIAASNEIPPENQGLEALYDRFIIRLLVPPIEQEENFNRLLDSKPSSDKPEI
                     SEDLRISYHELAKWREQLHKVRLSTDTLLIIKYIREELAAQFDKLGVYVSDRRWQRAA
                     VLLKASAFCNGRKETNHSDVILLKYCLWTTPENRESVEQIVMNAIKSCGFDTGIDLAE
                     LDREKESLDKEINKELYHSQDVYETVEMSGKKYFPVQAVFKNVHNSHANKELKIYVPY
                     SKFRSKEKFYPIDSTGNEIQEIECEFDGQGCCKLELKVRGGHWNEQYKPLKFKPNILF
                     HKGDKKSDVNERLIHSLTQSISDIRKQLIDTQKQVEKKYEKYQQYLQSPFVAQADIDV
                     AISGILDQIDKLNLRIKDCERLESLCR"
     gene            32064..33524
                     /locus_tag="ACFOV4_000695"
     CDS             32064..33524
                     /locus_tag="ACFOV4_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003758253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HFC7618760.1"
                     /translation="MSLNRKLSEQIRWIKASLQIDYADLFKQHGSLNGQIQQRLSDWQ
                     YQAKLALLQKNPFILHEEKLKKHQQTEIFNQQSVDDYRYFCKLAGVPFEKEFWQQELT
                     QSKNSKPNKQNLPLKLLTGKWQQQLDYAKSQWYLKQLNQLRQEFIDKLKQELDTIRQL
                     AEQLEQFGFEAGLWFDNSIGNLSQQNIEEMKRWLNYLTQDKNAQQIAELLGKMRQIEQ
                     SEKIEQVKQTVYTKSPQIDVNSREEIIGLRLGKDLEYVLPSELALMADEETSTLFDLK
                     FLESKLMCFELQGMTYCDAPTEIIVEQKSQEDEKLGPMILCVDTSGSMVGLPENIAKA
                     MALFLGAKAKSENRSCFVINFSTGIETFELTSKTGISNLIAFLRQSFHGGTDAAPALR
                     HALKMMEQEIYQKADLLMISDFVMNSLPDDLLASIEIQRETGNQFNSLVIGDAFMSKR
                     LKTHFDREWIYNPNVQTIQELVQFKKDIFNKQVVNS"
     gene            complement(33610..>33876)
                     /locus_tag="ACFOV4_000696"
     CDS             complement(33610..>33876)
                     /locus_tag="ACFOV4_000696"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618761.1"
                     /translation="DNARRKFFGHREPCPAENTKGRVRRYGAGTGEEGGYGAWLASKK
                     LLKYGEFTGSGDVWGEGWEFLFCEVEKGRLKMGFRRPFLGWKGE"
BASE COUNT         8578 a        10008 c         8229 g         7061 t
ORIGIN      
        1 aaattgggcg tgaaaaccgg tttatccatc gataaaaacc ggctgcctta tttggacgaa
       61 tattacaaaa ccacgaaacc tgccggaact ttgttcgagc cggattacga agccttaaac
      121 gcctacaagc cgcagctcat catcatcggc agccgcgccg ccaaggcgtt tgacaaattg
      181 aacgaaatcg cgccgaccat cgaaatgacc gccgataccg ccaacctcaa agaaagtgcc
      241 aaagagcgta tcgacgcgct ggcgcaaatc ttcggcaaac aggcggaagc cgacaagctg
      301 aaggcggaaa tcgacgcgtc ttttgaagcc gcgaaaactg ccgcgcaagg caaaggcaaa
      361 ggtttggtga ttttggtcaa cggcggcaag atgtcggctt tcggcccgtc ttcacgactg
      421 ggcggctggc tgcacaaaga catcggcgtt cccgctgttg acgaagccat caaagaaggc
      481 agccacggcc agcccgtcag ctttgaatac ctgaaagaga aaaatcccga ctggctgttc
      541 gtcctcgacc gaagcgcggc catcggtgaa gagggtcagg cggcgaaaga cgtgttggat
      601 aatccgctgg ttgccgaaac aaccgcttgg aaaaaaggac aagtcgttta ccttgttcct
      661 gaaacttatt tggcggccgg tggcgcgcaa gagctgctga atgcaagcaa acaggttgcc
      721 gacgctttta acgccgcgaa ataatgaaac ggcggcattc gatgccgtct gaaacacgga
      781 tgcaaaccgc ttcctgtgtt tcagacggca ttgcccgata cggaggcttc aaacaaggct
      841 ttccgctccg acggttcgga ctgccttgtt tgaatcttct acgccgtaac gcttttccct
      901 tctgtttatg actgccaaac ctttttccct caacctgact aacctcctgc tgctggcggt
      961 gttgtttgcc gtcagcctgt cggtcggcgt tgccgatttc cgctggtcgg atgtgttttc
     1021 gctgtccgac agccagcagg ttatgttcat cagccgcctg ccgcgcacgt ttgcgattgt
     1081 gctgacgggc gcgtcgatgg cggtggcggg gatgattatg cagattctga tgcgcaaccg
     1141 ttttgtcgaa ccttctatgg cgggcgcgag ccaaagtgcg gctttgggtt tgcttctgat
     1201 gtccctgctg ctgcctgccg cgccgctgcc ggtcaaaatg tcggttgccg ccgttgccgc
     1261 gctaatcgga atgctggtgt ttatgatgct tatccgccgc ctgccgccga cggcgcaact
     1321 gatggtgccg ctggtgggga ttattttcgg cggcgtggtt gaggcggtgg cgacctttat
     1381 cgcgtatgaa aacgaaatgc tgcaaatgct cggcgtgtgg cagcagggcg atttttcgag
     1441 cgtgctgctg gggcggtacg agctgctttg gattacgggc ggtttggcgg tgtttgccta
     1501 tctgattgcc gaccggctga cgattttggg gctgggcgag acggtcagcg tgaatttggg
     1561 tttgaaccgg acggcggtgt tgtggtcggg gctgattatt gtggctttga ttacgtcgct
     1621 ggttatcgtt acggtcggca atattccgtt tatcgggctg gtcgtgccga acatcatcag
     1681 ccgcctgata ggcgacaggc tgcgccaaag cctgcctgcg gtggctttgt tgggcgcgtc
     1741 tttggtttta ttgtgcgata ttttgggacg cgtgattgtg tttccgtttg aaattccggt
     1801 ctcgaccgtc ttcggggtat tgggtacggc gttgtttttg tggcttttat taaggaaacc
     1861 tgcccatgcc gtctgaaaaa aatatcggtt ttatggcagg aagcagccgt ccgttgtggg
     1921 tagcttttgc attgttgctg gtttcctgcg tcctgtttat gacgctcaac gtcaaaggcg
     1981 attgggattt tgtactgcac ctgcgtctga ccaaacttgc cgcgctgctg atggtcgcct
     2041 atgcggtcgg cgtgtccacg caactcttcc aaacgctgac caacaatccg attctgaccc
     2101 cttcaatttt gggtttcgat tcgctgtatg tgtttttgca gaccttgctg gtgtttacgt
     2161 tcggcggcgt gggctatgct tccctgccgt tgacgggcaa attcggcttt gaacttgccg
     2221 ttatgatggg cggctcgctg ctgctgtttt acacgctcat ccgtcagggc ggacgcgatt
     2281 tgccgcgtat gattttaatc ggcgtgattt tcgggatttt gttccgcagc ctgtcgtcgc
     2341 tgctttcgcg catgatcgac cccgaagaat ttacggcggc gcaggcgaat atgtttgccg
     2401 gattcaatac cgtccacagc gagcttttgg gcataggcgc gctgattctg ctcgtcagcg
     2461 cggcggtcgt ttggcgcgaa cgctaccgct tggacgtaca ccttttgggg cgcgaccaag
     2521 ccgtcaattt gggcatcagc tacacgcgca acaccttgtg gatactgctt tggattgccg
     2581 cattggtggc gacggcgacc gccgtggtcg gcccggtaag ctttttcggg cttctcgccg
     2641 cctcgcttgc caaccacttt tccccgtccg tgcgccattc cgtccgcctg ccgatgacgg
     2701 tttgtgtcgg cggcatcctc ctggtcggcg gacagaccgt attcgaacac ttcttgggca
     2761 tgaaggcggt attaagcgtg gtggtcgaat ttgcgggcgg actcgttttc ctctatctcg
     2821 ttttaaaaca caaaaaatga cggatgccat ctgaacggca gcccgccccg aaaggacaaa
     2881 ccatatgacg caagaacgtt tacccgaatt tttcgaccgc gccccgacgc tgaccgtaca
     2941 agacccgctt gccgcattcc tcggcgcggc cgaaaacggc atcctcactt accgctacgc
     3001 cgatgccgtg cgcctgtgcg gacattcctg cccgaccgtc gcgggcgcgt acctgatggt
     3061 tatcaaaggt ctgaaagcac tttacggcga agagctgccc gaacgcggcg gcatcgaagc
     3121 ctttatgcag ggcgcgcgcg acgaaggcac ggtcggcgta accgcgtccg tcgtccaact
     3181 ccttaccggc gccgcacccg aaaccggctt tggcggcgta ggccctgccg gacgctttgc
     3241 ccgccgcaac ctcttgtcct ttggtgcagg cgaaatcaac ggcacactcg cgctccgccg
     3301 ccgcgatacc ggcaaaaccg tcgccgtcag cctcaacgcc gccctgcaac ccttcgcacc
     3361 cgaaatgcgc gaacttatgc ccaaaaccgt cggcggcagc gcaagcgcag aagaactcga
     3421 acgcttcgga caactctggc aggcacgcat taaagcattt ttgaccgaat cggcggacga
     3481 cccgcagttc gtcatcgtcc gcgaagtgtg agcgttcaga cggcattccg aatttcaaat
     3541 gccgtccgaa cccccgccaa acaacaacaa acctacgccc gacaagcatc cgccatgatt
     3601 accatccgca acgtcagcta ccgcatcggc acacgcccca tcctcgacaa cgtcagcctc
     3661 gacatccccg aaggcggcat taccgccctc gtcggcccca acggtgcggg caaatccacc
     3721 ctgttttcct ttatggcgcg gctgcgcccg cttgaaagcg gcagcatcgc ctaccgcggc
     3781 aaaaaccttg cctgcacccc caccgccgaa ctcgccaaaa ccctgtccat cctcacccaa
     3841 gaaaacagca tcatgagccg catcaccgtg cgcgacctgc tcatgttcgg ccgctatccc
     3901 taccatcaag gcagaccgac tgccgaatgc cgccgtatcg ttaacggtgc aatcgaagaa
     3961 ttccacctgc aagacttcgc cgaccgctac ctgaccgagc tttccggcgg acaacgccaa
     4021 cgcgccatga ttgccatggt gttctgccag cgcaccgact acgttttgct ggacgaaccg
     4081 ctgaacaacc tcgacatgta tcatgcccgc tccctcatgc aaatcctgcg ccggctgacc
     4141 gacgaacaca agcgcaccac cgtcgtcgta ttacacgaca tcaaccaggc cgccgcctac
     4201 gccgaccacg tcgtcgccat gaaaaacggc caagtcgcca tgcagggcaa gcccgacgac
     4261 attttcaccg ccgcaaacat caaaaccctg ttcgatatgg atgtgtccgt cctcgaccac
     4321 caaagcaaaa aactcatcgt ccaccatatc tgaagctcaa aaagaaaatg ccgtctgaaa
     4381 acctttcaga cggcatttcc attccaaacg ctcaaaccgc cgcgtccgca cgttcgcccg
     4441 tgcggatacg gattgcctcc tcgaccggca gcacaaaaat cttgccgtcg ccgatttttc
     4501 ccgaacgcgc cacctcgaca atcacgtcaa tcgcgcgttc cacagcgtca tccgccaaca
     4561 ccagctcgat tttgaccttg ggcaggaaat cgacagcgta ttccgcgccc cggtaaatct
     4621 ccgtatgccc cttctgcctg ccgaaccctt tgacctcgct gacggtcata cccgtaatgc
     4681 cgatttccgt caacgcctcg cgcacgtcgt cgagtttgaa cggtttgaca atcgcctcga
     4741 tttttttcat cacattctcc attaattaac gtaaacaaac gacaaatata gcagaaaccg
     4801 ccggcaaacg ataaacggta ctgttcgccc ggcgatgcgg cgatttgccg gaaaccgtca
     4861 ttcccgcgca ggcgggaatc ccgatctctg catttcagca atatttaaag gtttctgtaa
     4921 atccaaactt ccatattcct aaccgtacgg aaacgacggc atttgatcta aaaacatacg
     4981 gaagcagttg cccgcccctc tacttcctgc aattatccgc atacccggct ttgggtaaaa
     5041 atcagaaaaa cagataaaac ccttattcct taatatcttc agacggcacc tgtattttcc
     5101 ccaactgtat gccgtctgaa gattgtcaac attttaagcc aaaataccca agcaatacag
     5161 ccccgttgcg cgtataatga cagattttcc aaccgcattt gagagccgaa tccatgtctg
     5221 tcgttttgcc cttgcgcggc gttaccgccc tttccgattt ccgtgtcgaa aaactcttgc
     5281 aaaaagccgc cgcactcgga ctgcccgaag tcaaattaag cagcgaattt tggtatttcg
     5341 ccggcagcga gaaagcattg gatgccgcga ctgtcgaaaa actgcaagcc ttgttggcgg
     5401 cgcaaagcgt tgaacaaacg ccaaaagcgc gcgagggctt gcatttgttt ttggtaacgc
     5461 cccgtttggg tacgatttcg ccgtgggctt ccaaggcgac caatatcgcg gaaaactgcg
     5521 gtttggcagg catcgaacgc atcgagcgcg gcatggcggt gtggctggaa ggtcgtctga
     5581 acgacgatga gaaacagcaa tgggcggcgt tgctgcacga ccgcatgacc gaatccgtgc
     5641 tgcccgattt tcagacggca tccaaattat tccaccatct cgaatccgaa accttttcca
     5701 ccgttgatgt tttaggcggc ggtaaagagg ctttggtcaa agccaatacc gaaatgggtt
     5761 tggcactctc cgccgacgaa atcgattatc tggttgaaaa ctatcaggct ttgcagcgca
     5821 atccgtccga tgttgaattg atgatgttcg cgcaggcaaa cagcgaacac tgccgccaca
     5881 aaatcttcaa cgccgatttc atcctcaacg gcgaaaaaca accgaaatcc ctgttcggca
     5941 tgatacgcga cacgcacaac gcgcatcccg aaggtacggt cgtcgcttat aaagacaatt
     6001 cgtccgtaat cgaaggcgcg aaaatcgagc gtttctatcc ggatgcggcg gaaaaccaag
     6061 gctaccgttt ccacgaggaa gacacgcata tcatcatgaa agtggaaacg cacaaccacc
     6121 cgaccgccat cgcgccgttt gcgggcgcgg caacgggcgc gggcggcgaa atccgcgacg
     6181 aaggtgcgac gggcaaaggt tcgcgtccga aagcaggctt gaccggcttt accgtgtcca
     6241 acctcaacat cccctgcctc aaacagccgt gggaacaaga ttacggcaag ccggaacata
     6301 tttcctcgcc gctggacatt atgattgaag gccccatcgg cggcgcggcg ttcaacaacg
     6361 aattcggccg ccccaacctc ttgggctact tccgcacctt tgaagaaaaa tttgacggtc
     6421 aggttcgcgg ctaccacaaa ccgattatga ttgccggcgg tctgggcagc attcaggcgc
     6481 agcagacgca taaagacgaa atccccgaag gcgcattgct gattcaactg ggcggcccgg
     6541 gcatgcttat cggcttgggc ggcggcgcgg cttcttcgat ggataccggc acgaacgacg
     6601 cgtctttaga cttcaattcc gtacaacgcg gcaaccccga aatcgaacgc cgcgcgcagg
     6661 aagtcatcga ccgctgctgg cagctcggcg gcaaaaaccc gattatctcc atccacgacg
     6721 tgggcgcggg cggtttgtcc aacgccttcc ccgaactcgt caacgatgcc ggacgcggcg
     6781 cggtattcaa gctgcgcgaa gtgccgttgg aagaacacgg tttaacgcct ttgcaaatct
     6841 ggtgtaacga atcgcaagag cgttatgtgt tgtcgatttt ggaaaaagat ttggacacct
     6901 tccgcgccat ctgcgaacgc gaacgctgcc cgtttgccgt ggtcggcacg gcgaccgacg
     6961 acggccattt gaaagtgcgc gacgatttgt tcgccaacaa ccccgtcgat ttgccgctga
     7021 acgtcttgct cggcaaaccg cccaaaacca cgcgtaccga caaaacggtt acgccgtcca
     7081 aaaaaccgtt tcacgccgac gatatcgaca tcaccgaagc cgcctaccgc gttttgcgcc
     7141 tgcctgccgt agccgccaaa aacttcctga ttaccatcgg cgaccgcagc gtcggcggca
     7201 tgacccaccg cgaccaaatg gtcggcaaat accaaacccc cgtagccgac tgcgccgtta
     7261 ccatgatggg cttcaatacc tatcgcggcg aagcaatgtc tatgggcgaa aaaccgaccg
     7321 ttgccctgtt tgacgcgccc gcctcgggca gaatgtgcgt cggcgaagcc atcaccaaca
     7381 tcgcggcgat caacatcggc gacatcggca atatcaaact ctccgccaac tggatggcgg
     7441 cgtgcggcaa cgaaggcgaa gacgaaaaac tctaccgcac cgtcgaagcg gtttccaaag
     7501 cctgtcaggc attggatttg agcattcccg tgggcaaaga cagcctgtcg atgaaaaccg
     7561 tatggcagga tggcgaagag aaaaaatccg tcgtttcgcc gttaagcctg attatctccg
     7621 cgttcgcgcc ggttcaagac gtacgcaaaa ccgttacgcc cgaattgaaa aacgtcgagg
     7681 acagcgtatt gctgtttgtc gatttgggct tcggcaaagc gcgtatgggc ggctctgcat
     7741 tcggtcaggt atacaacaac atgagcggcg acgcgcccga tttggacgac acaggccgtc
     7801 tgaaagcgtt ttacaacgtg attcaacagc ttgtcgccga agacaaactc ttggcatacc
     7861 acgaccgcag cgacggcggc ttgtttgccg ttttggtaga aatggcgttt gcagggcggt
     7921 gcggcttgga tatagattta aatttattgc ttgcacaaac atttattacc aaccataccg
     7981 ctctgtctca atcattgcgg actgaagagg taaaagcgtt ggctgaatgg caagaaacca
     8041 ttgcccgcac attatttaat gaagagttgg gtgctgttat ccaagttaga aaacaagatg
     8101 ttgccgatat tatcaattta ttctatcaac aacagctgca tcataatgtc tttgaaatcg
     8161 gtacgttaac tgatgagaac acgttaatca tccgcgacgg gcaaacgcac cttatttctg
     8221 acaacctaat caaactgcaa caaacctggc aagaaaccag ccatcaaatc caacgcctgc
     8281 gcgacaaccc tgcctgcgcc gacagcgagt ttgccctgat tggcgacaac gaccgcagcg
     8341 cattgtttgc caacctgaaa ttcgacgtga acgaagacat cgccgcgccg tttatcaaca
     8401 gcggcgcgaa acccaaaatc gccatcctgc gcgaacaggg cgtgaacggg caaatcgaaa
     8461 tggccgccgc gttcacccgt gccggattcg atgcctacga cgtgcatatg tccgacctga
     8521 tggcaggccg cttccgcctt gccgacttca aaatgctggc ggcgtgcggc ggcttcagct
     8581 acggcgacgt actcggcgcg ggcgaaggct gggcgaaatc catcctgttc caccctgctc
     8641 tgcgcgacca gtttgccgcc ttcttcgccg acccggacac gctgacattg ggcgtgtgca
     8701 acggctgcca aatggtcagc aacctcgccg agattatccc gggtgcagag gcatggccga
     8761 agttcaaacg caacctgagc gaacagtttg aagcgcgcct aagcatggtt cacgtcccca
     8821 aatccgcgtc gctgattctg aacgaaatgc aaggctccag cctgcccgtc gtcgtcagcc
     8881 acggcgaagg ccgcgccgac ttcgcacttc acggcggcaa catttctgcc gatttgggca
     8941 ttgcgctgca atatgtggac ggtcaaaacc aagttaccca aacctatccg ctcaacccca
     9001 acggctcgcc gcaaggcatc gccggcatta ccaacgccga cggccgcgtg accatcatga
     9061 tgccccaccc cgaacgcgtg taccgcgccg cacaaatgag ctggaaaccg gaaggctgga
     9121 cggaactgtc cggctggtac cgcctctttg ccggcgcacg taaagccttg ggctaaccgc
     9181 cctactcaaa ccaatgccgt ctgaagaata tttcagacgg cattccggca caccatcctt
     9241 taaacggtat ccgtccaccg aggaacactc atgaaaatca cacccgtcaa agccctaacc
     9301 gacaactaca tctggatgat acagcacggc aaccatgccg tctgcgtcga cccttccgaa
     9361 ccctcgcccg tcttggaatt cctcgtccgc aaccgcctca tgcttgccca aacatgggta
     9421 acgcaccccc accccgacca cgagggcggt gcggcggcac tctggcgcgg ctacatggaa
     9481 tcgcccgttt acggcgaatc cgacatcgaa gcagcaaccc acaccgtaac cgccggcacc
     9541 caattcacct tcggcgacgg acaggttacc gtttgggcaa cacccggcca cacagaccgc
     9601 cacaccagct accttctcga aacttcagac ggcatacacg tcttttgcgg cgacaccctg
     9661 ttttccgccg gctgcggacg cgtgtttacc ggcacaatcg aacagcttta cgacagcttc
     9721 caacgcttca accgcctgcc tgaaaacacc ctgttctacc cggcacacga atacaccgcc
     9781 gccaacctgg attttgccgc ccatatcgag ccggacaacg ccgacattca gacggcactg
     9841 aaagcggcgg cgcatacgcc taccctgccc gttaccctcg cgcgcgaacg ccgcgtcaac
     9901 ccgtttttgc gcgtcgacct gccgcacgtc agagaccgcg ccgaggcatt gagcgggaaa
     9961 acgttaaaca gcagcctcga tacctttgtc gcgctgcgtg aacttaaaaa ccaataccgg
    10021 acgaaataaa acaacgggaa aacgcagcca ttcctaggat ttttattaaa atcttaaata
    10081 aaatcataca atcatcgcca atagacgaaa ggacaccgtt gccttataat caaacaaaaa
    10141 caaaatatat aatatagtgg attgaattta aatcaggaca aggcgacgaa gccgcagata
    10201 gtacggcaag gcgaggcaac gctgtactgg tttttgttaa tccactatat tgttaatcca
    10261 ctatataaat ccagcacaaa acgggatcgg tgattcttgt ccgcaagaat cgttgatttt
    10321 ctctattaca cggataatca tcatgcgctt cacacacacc accccatttt gttccgtatt
    10381 gtccaccctc ggtctttttg ccgtttcccc tgcttactca tccattgtcc gcaacgatgt
    10441 cgattaccaa tattttcgcg actttgccga aaataaaggc gcgttcgccg taggtgcaag
    10501 caatatttcc atccaagaca agcaaggcaa aatattaggc agggttctca acggcatccc
    10561 catgcccgac ttccgcgtca gcaaccggca aaccgccatc gccaccctga ttcaccccca
    10621 atacgtcaac agtgtcaaac acaacgtcgg ctacggttcc atacaattcg gcaacgacac
    10681 ccaaaatcca gaagaacaag cctataccta ccgcctcgta tcacgcaacc cgcacccgga
    10741 ctacgactac caccttcccc gcctcaacaa actggttacc gaaatctcac ctgccgcact
    10801 cagcagcgta cccttgcttg gaaacggcca gccaaaggcc aatgcctacc tcgataccga
    10861 ccgcttcccc tactttgtac gactcggctc aggcacgcaa caagtccgca aagcagacgg
    10921 cacgcgcaca caaaccgccc cggcatacca atacctgacc ggcggcacgc cgctgaaagt
    10981 attgggtttc caaaaccacg gcttactcgt cggcggcagc ctgaccgacc aaccccttaa
    11041 cacctacgca atcgccggag acagcggttc ccccctgttt gccttcgaca agcatgaaaa
    11101 ccgctgggtg cttgcgggcg tactcagcac ctacgccggc ttcgacagct tcttcaacaa
    11161 atacatcgtc acgcaacccg aattcatccg ttccaccatc cgccaatacg aaacccggct
    11221 ggatgtcggg ctgaccacca acgaactcat atggcgcgac aacggtaatg gcgacagcac
    11281 cctgcaaggg ctcaacgaac gcatcaccct gcccattgca aacccttcgc ttgccccaca
    11341 aaacgacagc aggcacatgc cgtctgaaga tgccggcaaa acgctcatcc tatccagcag
    11401 gttcgacaac aaaacactga tgctggcaga caatatcaac caaggcgcag gcgcattgca
    11461 gttcgacagc aacttcaccg tcgtcggtaa aaaccacaca tggcaaggtg caggcgttat
    11521 cgtagccgac ggcaaacgcg tcttctggca agtcagcaac cccaaaggcg accggctctc
    11581 caaactgggc gcaggcacgc ttatcgccaa cggacaaggc atcaactagg gcgacatcag
    11641 catcggggaa gacactgtcg tactcgccca aaaagctgct tcagacggca gcaaacaagc
    11701 attcaaccaa gtcggcatca ccagcggcag gggcacggcc gtcctcgccg acagccagca
    11761 aatcaaaccc gaaaacctct atttcggctt caggggcgga cggctcgacc tcaacggcaa
    11821 caaccttgcc tttacccata tccgccatgc ggacggcggc gcgcaaatcg tcaatcacaa
    11881 ccctgaccaa gccgcgacac tgacgctgac cggcaacccc gtcctcagtc ccgagcatgt
    11941 cgagtgggtg caatggggca accgtccgca aggcaacgcg gcggtttacg aatacatcaa
    12001 cccgcaccgc aaccgtcgga ccgactactt catactcaaa cccggcggca acccgcgcga
    12061 atttttcccg ttaaatatgg aaaactcaac aagctggcaa tttatcggca acaacaggca
    12121 acaggccgcc aaacaagtcg cccaagccga aaatgcccgc cccgacctaa ttaccttcgg
    12181 cggatacttg ggtgagaacg cgcaaacggg caaagccgca ccgagttaca gcaaaaccaa
    12241 tatcgaatgg gtgaatggtc caaacacccc acacaagccc tcgccctata cgaatacgcc
    12301 aacccgcaca ggggcaggcg taccgacgat taccgcctca aagaaggcgg caaccccggc
    12361 gcctacttcc catggaatgc ctacagcacc caagactggg aatttctcgg acatgaccgg
    12421 cgaagcagcc atagaaaaaa cccgccatat cgcaaatgcc gccgtatacg gccggcccga
    12481 ataccgttac aacggcgcac tcaacctgca ctatcgtccc aaacgcaccg acagcacgct
    12541 gttgctcaac ggcggcatga accttaacgg ggaagtcttg attgagggcg gcaatatgat
    12601 tgtgtcaggc aggcccgtac cccatgccta cgaccaccag gccaaacgcg aacccgttct
    12661 tgaaaacgaa tggaccgacg gcagcttcaa ggctgcacgg ttcaccctgc gaaaccatgc
    12721 ccgactgacg gcagggcgca ataccgcgca tctggacggc gacataaccg catacgatct
    12781 gtccggcatc gacctcggct ttatccaagg caaaacaccg gaatgctacc gctcctacca
    12841 tagcggcagc acccactgca cacccaacgc cgttttaaaa gccgaaaact atcgtgcact
    12901 acctgcaacg caagtacgcg gcgacattac ccttaacgac cgttcagagc tccgcctggg
    12961 caaagcacac ctgtacggca gcatccgtgc cggcaaagac accgcagtcc gcatggaagc
    13021 agacagcaac tggacacttt cccagtccag ccacaccggc gcactgacgc ttgacggcgc
    13081 acaaattacc ctgaaccccg atttcgccaa taatacacac aacaaccgct tcaacacact
    13141 gaccgtcaac ggcacacttg acgggttcgg cacattccga ttcctgaccg gcatcgtccg
    13201 aaaacaaaat gccccccctc aaactggaag gggacagccg cggcgcattc caaatccacg
    13261 tcaaaaacac cggacaagaa cctcaaacaa ccgaatcgct tgcacttgtg agcctcaatc
    13321 cgaaacacag ccaccaagcc cgattcaccc tccaaaacgg ctatgccgat ttgggtgcct
    13381 accgctacat cctccgcaaa aacaacaacg gatacagcct gtacaacccg ctcaaagagg
    13441 ccgaacttca aattgaagcc acgcgtgcgg aacatgagcg caaccaacag gcatacaacc
    13501 aattacaggc aaccgacatc agcagacagg ttcaacatga ctctgacgcg accaggcagg
    13561 cactacaggc ctggcagaac agtcaaaccg aacttgcccg catcgacagc caagtccaat
    13621 atctgtccgc ccaattgaaa cagacagacc cgctgaccgg cattctgacg cgtgcccaaa
    13681 acctgtgtgc cgcacaagga tacagtgtcg atatctgccg tcaggttgcc aaagccgccg
    13741 acacgaacga cctgacactc ttcgaaaccg aactggatac gtatatagaa cgtgtagaaa
    13801 tggccgaatc cgaacttgac aaagcacggc aaggcggcga tgcgcaagcc gtcgaaacag
    13861 cccggcacgc ctacctgaac gcactcaacc gtctgtcccg acaaatccac agtttgaaaa
    13921 ccggcgttgc cggcatccgt atgccgaacc tggccgaact gatcagccgg tcggccaaca
    13981 ccgccgtttc cgaacaggcc gcctacaata ccggccggca acaggcggga cgccgcatcg
    14041 accgccacct taccgatccg cagcagcaaa acatctggct ggaaaccggt acgcaacaaa
    14101 ccgactacca tagcggcaca caccgtccct accaacaaac taccaactat gcacatatcg
    14161 gcatccaaac cggcatcacc gaccgtctca gtgtcggtac gattttaacc gatgagcgca
    14221 caaacaaccg ttttgatgaa ggcgtatccg cccgaaaccg cagcaacggc gcacatctgt
    14281 tcgtcaaagg ggaaaacggc gcactctttg ccgcggcaga tttaggctac agcaacagcc
    14341 gtacccgatt taccgattat gacggggctg ccgtccgccg ccacgcatgg gatgcaggca
    14401 tcaacaccgg catcaaaatc gataccggca tcaacctcag accctatgcc ggcatccgta
    14461 taaaccgcag caacggcaac cggtacgtac tcgacggcgc agagataaac agcccggcgc
    14521 aaatccaaac cacatggcat gccggcatcc gtctcgataa aaccgtcgaa ctgggtcaag
    14581 ccaagctgac ccccgctttc agcagcgatt actaccatac ccgccaaaac agcggttccg
    14641 ccctcagcgt caacgaccgt accttactgc agcaagccgc ccacggcaca ctgcataccc
    14701 tgcaaatcga cgccggatac aaaggctgga acgccaaact tcatgccgct tacggcaaag
    14761 acagcaacac cgcccgccac aaacaggcag gaatcaaaat aggctacaac tggtaacaag
    14821 ccgataaaaa tgccgtctgg aacccgcgtt tcagacggca tttgcgttaa aaatagtaaa
    14881 ccgttccaaa agggagtaga atagtgccgt ttccaaccct gcgcctgtac cgtcaggctt
    14941 ttattatgga ccttcccagt tcgtttttac tgaacacccc ttccgattcc aaacgacaat
    15001 aaccatcccg ccggaatgcc tccccgcaca cggcgggcgg agcatttatg agcatcgaac
    15061 caacccctcc gaaccttgaa aacgacggta tcgaaaacga tgtagaacgc gtttccgccg
    15121 atttcgaccg tgtccactcc ctctgcgaaa tcctcgaacc tgcttttgaa caaatcgaaa
    15181 acggtacacc gctcgaagac gcgccgctgc gcgacaagct gaccgagctg accgtcctct
    15241 tgagcgagct gcaccctgcc gacgtggcgg cggtattgga atcgctaccg ccgcgcgaac
    15301 gcaatatcgt ctggattctg gtcaaaccgg aagacgacgg cgaagtattg ctggaagtat
    15361 ccgacgcggt gcgcgaaacg ctgatcgagt cgatggacaa agacgaattg ttggcagcgg
    15421 tcgatgattt ggacgcggac gaattggcgg aactggcaga cgatttgccg caccaagtgg
    15481 tttacgaagc gctacaaacc cgcgatgagg aagaacgcgc ccaagtcaaa gcggcaatgt
    15541 cctacgaaga caaccaagtc ggtgcgatta tggacttcga gttggtcagc atccgcgccg
    15601 atgtcgcctg tgaagtggtg ctgcgctatc tgcgccgctt cgacagcctg cccgaccata
    15661 ccgacaagat ttttgtggtc gatgaaaacg acgtactgca aggcgtgctg cccatccgca
    15721 aacttttggt cgccgatccc gaagatttgg tggaaaacgt gatggcgaaa gatgtcgtgc
    15781 gtttccgcgc cgaagacgac gtggaagaag cggcgcaggc gtttgaacgc tacgacttgg
    15841 taactgcgcc ggttgtcgat gaaaacaaaa agctcatcgg taggattacc gttgacgaga
    15901 tggtggacgt gatccgcgaa gaatccgaag cggatatgtt gaacatggcg ggtttgcagg
    15961 aagaggaaga cttattcgcc cccgtcttgg attccgtcaa aaaccgctgg atgtggctcg
    16021 ccgtcaacct ctgcaccgcc ttcctcgcca gccgcgtcat cggcgcgttt gaaagcagca
    16081 tcgaaaaaat cgtcgcactc gccgcgctga tgcccatcgt cgccggcata ggcggtaact
    16141 cgggcaacca gacgattacc atgattgtcc gcgcgatggc gatggggcag ctgacggata
    16201 tgcaggcggg acgtttgctg aaaaaagaag tcagtgtcgc cctggtcaac ggcatcattt
    16261 ggggagcggt catgggcgca gtatcttggc tgctctacgg cagcctcggc atcgggctgg
    16321 ttatgattgc cgcgatgacg ctcaacctcc tgctggcggc aaccgtcggc gtattgattc
    16381 ccgtggtaat ggaaaagttc ggacgcgacc ccgcgctggg cagctcggtg ctgattacgg
    16441 cggtaacgga ttccggcggc ttcctgattt tcttgggtct cgccaccctg ttcctgcttt
    16501 aaatgccgtc cggacccgcg caaaaatgcc gtctgaagcg gaagctgctt cagacggcat
    16561 ttgactattt atccttgttg cacaagatta ttggacggta tgccggggca gccctttggc
    16621 aacgccgacc acatcctccc cgaacagcac gttgacatcg gtttcgtcaa acacatattt
    16681 gctgtggcag aaatcgcaat cgacttcgat gctgccttgt tccaccacca cgccgccgac
    16741 ttcttccccg cccagcatca acagcatatc gctgactttg ccgcgcgaac aggtgcatga
    16801 aaattcaaac gtttccggct cgaacacgcg cggcggcgtt tcgtggaaca ggcggtataa
    16861 aacgtgttgc gcatccaatt ctgccagctc ctccgccgtc agcgtgcgcg ccagcgtact
    16921 gacgtgttcc catgcctctt catccaacac ctcttcaggc agacgctgca ccagcagacc
    16981 gcccgccgct tcatcgcttg cagacaggac gatgtgcgta tcaagctgtt cggaacgttt
    17041 catatagttc atcaacattt gcgcgatacc gtcgccttcc aaaggcacta cgccctgcca
    17101 gggttcgccg tctttgggct gcagcgtcag cacgaatacg ccgccctcgc ccaaaagatc
    17161 gaccaaactt tcatcttcac cgatttctgc cgcctcgtcc caccgcgcgg ttgcacggac
    17221 ggtacggtcg gaagtcgctt ccgcaaccag cattttcagc cgcccctgcc cctgaacctg
    17281 cacaatcagc gtgccttcgt ttttgaggtt gcccgacagc agaacaccgg cagccaacag
    17341 ctcgcccaag gcgcggcgga tggcggcggg atagtttttc tgttttacaa tgtgctgcca
    17401 cacgttttcc agacggacgt gcagcccgcg cacgggcata tcgtcgaaga taaagcgggt
    17461 acgcacatcg gcgcggttga tggcggtttg attcatgatt ttctctgact gattgttcgg
    17521 atggcggcta tatggttgcg gtcggcgcga aaacaagacg gacggcggat gcgcttccca
    17581 aattatcaat aaattatata aaaatcaaca tattaactca atctaacaag ccgttttttg
    17641 ccaaacagcc gtttttttat atacaatcaa caagatattt tcgactgata cagcataaca
    17701 tcgcacggcg gcacgatgcc tcctgcgcgg aaacaccgat atggattctt ttttcaaacc
    17761 ggcagtttgg gcggttttgt ggctgatgtt tgccgtccgc cccgcccttg ccgacgagtt
    17821 gaccaacctg ctcagcagcc gcgagcagat tctcagacag tttgccgaag acgaacagcc
    17881 cgttttaccc atcaaccgag cccccgcccg acgggcgggc aatgccgacg aactcatcgg
    17941 cagcgcgatg gggcttaacg aacagcccgt tttacccgtc aaccgagtcc ccgcccggcg
    18001 ggcgggcaat gccgacgaac tcatcggcaa cgcgatgggg cttaacgaac agcccgtttt
    18061 acccgtcaac cgagcccccg ctcggcgggc gggcaatgcc gacgaactca tcggcaacgc
    18121 gatgggactt ttgggtattg cctaccgcta cggcggcaca tcggtttcta ccggttttga
    18181 ctgcagcggc ttcatgcagc acatctttaa acgcgccatg ggcatcaacc tgccgcgcac
    18241 gtcggcagaa caggcgcgga tgggtacgcc ggttgcccga agcgaattgc agcccgggga
    18301 tatggtgttt ttccgcacgc tcggcggcag ccgcatttcc catgtcggac tttatatcgg
    18361 caacaaccgc ttcatccacg cgccgcgcac ggggaaaaat atcgaaatca ccagcctgag
    18421 ccacaaatat tggagcggca aatacgcgtt cgcccgccgg gtcaagaaaa acgacccgtc
    18481 ccgctttctg aactgatttc ccaaggaata cgcaatgagt atgcccgaaa tgcccaaatg
    18541 gtacgacgat gacggacaga tcgtgtcctg taccgaaaag gtcaaagtga tgtccgaaaa
    18601 tatggccgag ctgtatcaga cggcacaaga cgcgtttgaa gacgcgctgc tgatgggttg
    18661 cggcgaacgt cagttgcgcg attacctgct cgcgctgatt gaaggtttgg aaaatcccta
    18721 ccgcaaagtc tgaacacgcc ccggttgctg cggcacggtt tatccgtgcc gtttttgcgt
    18781 ttgtgcgcgg cttcggcttt tcagacggca tatttgacgt tatgattaaa cagttaacaa
    18841 gatttatcac aacgccgtca aaagacagac acacaacatg aacatcatcc gcgcgctcct
    18901 catcatcctc ggctgcctcg ccaccggcga aaccgccgtt ttcctagcag gcatcaaact
    18961 gcccggcagc atcgtcggca tgggcgtgct gtttgcgctt ttgcaggcgg gttgggtcaa
    19021 aacgtcttgg ctgcaacagc ttaccgacgc gctgatggcg aatctgacgc tgtttctcgt
    19081 gccgccctgc gtggcggtca tcagctattt ggatttgatt gccgacgatt ggttttcgat
    19141 actggtttcc gcctccgcca gcactttgtg cgtactgctg attacaggca aggttcaccg
    19201 ctggatacgg agcattatct gatgaacgaa atcctcaggc agcccagcgt tctgcttttc
    19261 ctcacgcttg ccgtgtacgc gcttgcgatt atcgtgcgca cgcgcacggg caatatcttc
    19321 tgcaaccccg tactcgtcag caccgtggtg ctgattgcct acctgaaaat cctcggtatc
    19381 gattacgcgg tgtaccacaa cgccgcgcag tttatcgatt tctggctcaa gcccgccgtc
    19441 gtcgtgcttg ccgtgccgct ctaccaaaac cgccgtaaaa tcttcaacca atggctgccc
    19501 gtcatcgttt cacagcttgc gggcagcgtt acgggcattg ttacggggat gtattttgcc
    19561 aaatggctgg gcgcggaacg cgaagtcgtc ctctcgctcg cgtccaaatc tgttaccaac
    19621 cccatcgcca ttgaaattac ccgctccatc ggcggcattc ccgccattac cgccgccacc
    19681 gtcatcattg ccggtctagt cggacagatt gccggttaca aaatgctgaa gaacacagtc
    19741 gtcatgccct cgtccgtggg tatgtcgctc ggcacggctt cgcacgcgat ggggattgcc
    19801 gcctcgctcg aacgcagccg ccgcatggcg gcatacgcgg gactggggct gacgttcaac
    19861 ggcgtactga ccgcgctgat tgcgccgctg ctcatccccg ttttgggatt ttgaacccgt
    19921 ttcagacggc atttcagccc atgctgtctg aacgccgaca cactcgcaag gagaaccgtt
    19981 atggctgtca acctgactga aaaaaccgcc gaacaactgc ccgacatcga cggcattgcc
    20041 ctctacaccg cccaagcagg cgtgaagaag cccgggcata ccgacctgac actgattgcc
    20101 gtagccgccg gcagcaccgt cggtgcagtc ttcacgacca accgtttctg tgccgcgccc
    20161 gtccacatcg ccaaatcgca ccttttcgac gaagacggcg tgcgcgccct catcatcaac
    20221 acgggcaacg ccaacgcggg tacgggcgca cagggcagaa tcgatgcttt ggcagtgtgt
    20281 gccgccgccg cccggcaaat cggctgcaaa ccgaaccagg tgctgccctt ctccaccggc
    20341 gtgattctcg aaccgctgcc cgcagacaaa atcatcgccg cgctgcccaa aatgcagcct
    20401 gccttctgga acgaagcggc acgcgccatc atgaccaccg acaccgtgcc caaagccgcc
    20461 tcgcgcgaag gcaaggtcgg cgacaaacac accgtccgcg ccacgggcat cgccaaaggc
    20521 tcgggcatga ttcatcccaa tatggcgacc atgctcggtt tcatcgccac cgatgccaaa
    20581 gtttcccaac ccgtcctcca actgatgacg caggaaatcg ccgacgaaac cttcaacacc
    20641 atcaccgttg acggcgacac cagcaccaac gacagcttcg tcatcatcgc caccggcaaa
    20701 aacagccaaa gcgaaatcga caacatcgcc gacccgcgtt acgcccaact caaagaattg
    20761 ttgtgcagcc tcgcgctcga actcgcccaa gccatcgtcc gcgacggcga aggtgcgacc
    20821 aagttcatca ccgtccgcgt cgaaaacgcc aaaacccgcg acgaagcccg ccaagccgcc
    20881 tacgccgtgg cacgttcgcc gctggtcaaa accgcctttt tcgcctccga ccccaacctc
    20941 ggcaggctgc tcgccgccat cggttatgcc ggcgttgtcg acctcgatac cgacctcgtg
    21001 gaaatgtatc tcgacgatat tttggttgcc gaacacggtg gacgcgccgc aagctacacc
    21061 gaagcacaag ggcaggcggt gatgtcgaag gccgaaatca ccgtccgcat caagctgcat
    21121 cgcggacaaa gtgccgccac cgtctatacc tgcgacctgt cgcacggata cgtttccatc
    21181 aacgccgact accgttcctg acccgacacg gcttcagacg gcatacataa aatgccgtct
    21241 gaaccgccgg acaacatgcc atgacctcca cattcccccg ccgcctcgcc cgcaaaatcc
    21301 gccaaacccg ccgcctgtcg cgcaaaagca tcgcctttct gttccttttg gcaggttcgg
    21361 cactcgtcgc cctgaccgcg ctgttttttg cccatcttgc cgattttgcg ctggaactga
    21421 acgccaaact ggttcaacaa tacccgtggt tcgcgtgggt cgcgcttcct ttgggtttac
    21481 cgcttattgc gtggctcaca cgcaaattcg cccccttcac cgccggcagc ggcatcccgc
    21541 aggtcatcgc ctcactgtcg ctgccctacg gcgcacagaa aacgcggctg atccgcctcg
    21601 ggcagacgct gctgaagatt ccgctgacct ttttgggtat gctgttcggc gcgtccatcg
    21661 gacgcgaagg tccgtccgtg caggtcggcg cggcagtgat gggcgcgtgg ggcgcgtggt
    21721 gcaagaaaca cggcttggca ttcaaaggga tgcaggaaaa cgatttgatg gcggcgggcg
    21781 cggcgggcgg tttggcagcc gcgttcaacg cgccgctggc gggcgtgatt ttcgccattg
    21841 aggaactcgg gcgcggcatc atgttgcgct gggaacggca gattctgctc ggcgtactcg
    21901 ccgccggttt catacaggtc gccattcagg gcaacaaccc gtatttttcc ggcttcaacg
    21961 gcggcgtatt ggaacatatc tttctgtggg tcgcactgtc cggcctggtt tgcggcgcgg
    22021 cgggcgggct gttcggacgt ttgctctatc gcggtgcggc ggcgtttgca ccgcgcaaga
    22081 tacgcggctt catccgcaac cgtccgctgc tgctggcggc actgatgggg ctgctgctcg
    22141 ccctgctcgg cacgttctac caaggcaaaa cctacggcac cggctaccac gaagccgccc
    22201 aagccctgca cggcatctac gaagccccct tcggactcac cgccgccaaa tggctcgcca
    22261 ccgtattcag ctattgggca ggcattccgg gcggcatttt cactccctcg ctgaccatag
    22321 gcgcggtttt gggcgagcat atcgccgcca tcgccgacat atcgcagggt gcaaacatca
    22381 tcgtcctcat ctgcatggcg gcatttctgg cgggcgcgac acaatccccg attacttccg
    22441 ccgtcgtcgt catggaaatg acgggcggac aaagcctgct gttttggatg ctgattgcct
    22501 gcattttcgc ctcgcaggtt tcgcgccagt tttcgccgcg tccgttctac cacgcatcgg
    22561 gaatgcgctt ccgccagcgc gtgcttcaag aaaccgccgc ccaaaccggc aatgcgcccg
    22621 caagaccgca aacagcaaaa cgggaatgcc gtctgaaaat taaaacgccc ccgatcaaac
    22681 gccggcagcc gccttgattc gaataccgtt ccgccgccgc ttgaaatttc agcaacaatg
    22741 ccgtctgaac gacagaatgc ggttttcaga cggcatttcc ccatcccgat attgcctaaa
    22801 caaaaccgaa gcgtttgcta taattgcact ttttaccgca cacgcacgcc catgtttccc
    22861 gatttctccc aaaccctctc caaagaccgc cacttcctgc aatccgcctt caaaaatccc
    22921 aacaaatacg gcggtttgtc caaagtcgaa gaaaaatacc gaaaatcgca cgaaatcttt
    22981 ttgaggcgtt tggccgcatt gcccaaaccc gaattcgaca acaccctgcc cgttcacgaa
    23041 aaactcgaag aaatcaaaaa aaccgttgcc gaacatcagg taacgattat ttgcggcgaa
    23101 accggttcgg gcaagaccac tcagttgccc aagatttgtt tggaactcgg gcgtggggcg
    23161 gcggggctga tcgggcatac ccagccgcgc cgtttggccg cgcgctccgt ggcagagcgg
    23221 attgccgaag agctgaaatc cgaaatcggc agcgcggtcg gctataaagt acgcttcacc
    23281 gaccacacct cgcgcgatgc ctgcgtcaag ctgatgaccg acggcatcct gctggcggaa
    23341 acgcagaccg accgttatct cgccgcctac gacacgatta tcatcgacga agcgcacgag
    23401 cgcagcctga acatcgactt ccttttgggc tatttgaaac aactcctgcc gcgccgcccc
    23461 gatttgaaag tcatcatcac ctcggcaacg atagacgcag aacgcttctc ccgacacttc
    23521 aacggcgcgc ccgttttaga agtgagcgga cggacgtatc ccgtcgaaat cctctaccga
    23581 ccgctgaccg gcaaagacga agacgacgca gaagtggagt tgaccgacgc gattgtcgat
    23641 gcggcggacg aattagcgcg acacggcgaa ggcgatattt tggtattcct gccgggcgag
    23701 cgcgaaatcc gcgaagccgc cgaagccctg cgcaaatcca cgctgcgccg caacgacgaa
    23761 atcctgcccc tgttcgcacg cctgtcgcac gccgagcagc acaaaatctt ccacccctca
    23821 ggcgcgaaac gccgcatcgt attggcaacc aacgtcgccg aaacctcgct taccgtgccg
    23881 ggcatcaaat acgtcatcga caccggcctc gcgcgtgtta aacgctattc cgcacgggcg
    23941 aaagtggagc agcttcatat cgaaaaaatc tcccaagccg ccgcccgcca acgatccggc
    24001 cgctgcggac gcgtctccgc aggcgtgtgt atccgactgt tttcagaaga agatttcaac
    24061 agtcgccccg aatttaccga ccccgaaatc gtccgcagca acctcgccgc cgtcatcctg
    24121 cgcatggcat cgctgaaact cggcgacgta gcggcattcc catttttaga aatgcccgat
    24181 tcgcggtata ttaatgatgg gtttcaggtg ttgctggaat taggggcggt ggaggccgcc
    24241 tgaaaacaag taggatatac acttctacct gacaaagacc aacaaacgat aaaactacgg
    24301 cacatctaga tgcccaacct acaacattgc acacggtaaa aacatgaaac acttactcat
    24361 cgattttgaa aacgtccagc cgcaaaactt agacaaatta ctaaccgaaa atacccatat
    24421 ttggctattt ataggtgtat tacacaaaat gttacctatt agtctggtgc aatccctact
    24481 acgtttcggc gaacgtgtcc atcttgtcca gttacaaaaa acagggaaaa acgcattgga
    24541 tttttacctg tcctattacc tcggacaaat taccgccaca gaccccaatg cccaaatcgg
    24601 catactctcg cgtgatggag gatacgatgt tctggtcgaa catattttga aaaaccacca
    24661 ggcgaagggt atcgtgcgcc tagccaatat agatgaagta caacatcaga aaattactac
    24721 cgaaccgccg tcagcattgc tggaaaacac tcctcagcct gaaaccaccc tcaaaccaca
    24781 gcaaccatta acttcctatt tccaagcagc cctaactgca ctgcgccgcc ccgacgcttt
    24841 ccgcccctgc cgcctgcata acctgcgaca aaatctgcgt aagcatattt tgagtgattt
    24901 gtttaaagaa aaaaccgatg aagaatgcga aataaccact gctaacgtta tcaataaact
    24961 caaagcacaa aacttcatca gcattgatga acaggaaacc gtttcctacc atctcagtga
    25021 taatgatttg ttacaaagaa tccaacgcca tattttaagc caacgtccca aaacctacgc
    25081 tgattttcaa gccgtcgtgc aaaaccgagc agatgcactt cacttaacag tcggtaccaa
    25141 cgacattcaa tcctttgcgc gacatttgcg cgaccaaaac ctgatccgcc aaaacaatgg
    25201 gaaaattgaa tatgcaccgt ttactgaacc taaaccacag ccaacgccca agcagcctaa
    25261 aaaaaccgca tgggaacctg atgaaattat ttggaaaaaa gtgattgccg cgttatcgtt
    25321 aaagaaccgt cctaataaaa ccaaaacttt acgcaataca atccaggcac tcacaaaatc
    25381 caatgcacaa gaaactgaca aactgctaca acatttacaa ggtacccaag tcctacgtat
    25441 tgacggtact aaaattgtgt atatcaagta ggatgggcat ttatgcctga cctacaaaac
    25501 caaaaacaac ctaccgccct taatcaactc cacaaaccct tttcagacaa cctcgttttt
    25561 tgaaaaacaa tctgtaaaca gataactgct gaagaatacc gttgccgagc cccaaaacct
    25621 gcctgcaact tttattgtga acttcccatt atgaaaaaat cccttttcgt tctctttctg
    25681 tattcatccc tacttaccgc cagcgaaatt gcctatcgct ttgtattcgg aattgaaacc
    25741 ttaccggctg caaaaatggc agaaacgttt gcgctgacat ttgtgattgc tgcgctgtat
    25801 ctgtttgcgc gttataaaac ttcgcggctg ctgattgcgc tgtttttcgc gttcagcatt
    25861 attgccaaca atgtacatta tgcggtttat caaagttgga tgacgggtat taactattgg
    25921 ctgatgctga aagaggttac cgaagtcggc agtgcgggcg cgtcgatgtt ggataagttg
    25981 tggctgcctg cgttgtgggg cgtgttggaa gtcatgttgt tttgcagcct tgccaagttc
    26041 cgccgtaaga cgcatttttc tgccgatata ctgtttgcct tcctaatgct gatgattttc
    26101 gtgcgttcgt tcgacacgaa acaagagcac ggtatttcgc ccaaaccgac atacagccgc
    26161 atcaaagcca attatttcag cttcggttat tttgtcggac gcgtgttgcc gtatcagttg
    26221 tttgatttaa gcaggattcc cgcctttaag cagcctgctc caagcaaaat caggcagggc
    26281 agtgttcaaa atatcgtcct gattatgggc gaaagcgaaa gcgcggcgca tttgaagctg
    26341 tttggctacg gacgcgaaac ttcgccgttt ttaacccggc tgtcgcaagc cgattttaag
    26401 ccgattgtga aacaaagtta ttccgcaggc tttatgactg cagtgtccct gcccagtttt
    26461 ttcaatgcga taccgcacgc caacggcttg gaacaaatca gcggcggcga taccaatatg
    26521 ttccgcctcg ccaaagagca gggctatgag acgtattttt acagtgctca ggctgaaaac
    26581 caaatggcaa ttttgaactt aatcggtaag aaatggatag accatctgat tcaaccgacg
    26641 cagcttggct acggcaacgg cgacaatatg cccgatgaga agctgctgcc gttgttcgac
    26701 aaaatcaatt tgcagcaggg caagcatttt atcgtgttgc accaacgtgg ttcgcacgcc
    26761 ccatacggcg cattgttgca gcctcaagat aaagtattcg gcgaagccga tattgtggat
    26821 aagtacgaca acaccatcca caaaaccgac caaatgattc aaaccgtatt cgagcagctg
    26881 caaaagcagc ctgacggcaa ctggctgttt gcctatacct ccgatcatgg ccagtatgtt
    26941 cgccaagata tctacaatca aggcacggtg cagcccgaca gctatctcgt gccgctagtg
    27001 ttgtacagcc cggataaggc cgtgcaacag gctgccaacc aggcttttgc gccttgcgag
    27061 attgccttcc atcagcagct ttcaacgttc ctgattcaca cgttgggcta cgatatgccg
    27121 gtttcaggtt gtcgcgaagg ctcggtaacg ggcaacctga ttacgggtga tgcaggcagc
    27181 ttgaacattc gcgacggcaa ggcggaatat gtttatccgc aatgagtggc gtaaaaacca
    27241 ataaagacaa atttagatga tgtcggggaa gatgcccgac cgacaagact atgcaaaata
    27301 tgaaaaacca agtacgcgga tcaggcatgg atgcccgatc caatccggtc aatgtttcag
    27361 acggcctgca aaacagttcg ggtcatatcg gtaccaacac gcgttaccgc ctgaccaaac
    27421 tcggcgaaca aatggcgcgc ctgcccatcg acccgaaaat cgcgcgcatt ttgctggcgg
    27481 cgaagaaaca cgactgcatg gcggaaatat tggtgatagc gtccgcgctg tcgattcaag
    27541 acccgcgcga gcggccgttg gaagcgcgcg atgccgccgc caaggcacac gagcgtttta
    27601 ccgacaagca atccgacttc cttgcctatc tgaacatttg ggacagcttc cagcgcgagc
    27661 gcgacaaagg tttgtccaac aagcagttgg tgcaatggtg ccgtcaatat ttcctgtcgc
    27721 acctgaggat gcgcgagtgg cgcgagttgc accaccagct tgcccaaacc gcgattgaaa
    27781 tgggtttgac caccaaggaa gcggctttca gacggcctcc cgaaatcagg cagctcacgt
    27841 cgtctgaaag ccaaggcgac caagatttgg cggccaaact caaacaaaaa caactggata
    27901 agaagcaaca ccgcgcccaa atccgcgccg ccaaagaagc gggctacgaa caaatccacc
    27961 gcgccctgct gaccggcctt atcgccaacg tcggcatgaa atcgcccgac ggcaacgact
    28021 acaccggcgc acgcggcagc cgttttcatc ttttcccggc atcagccctg ttcaaagcca
    28081 agcccaaatg ggtgatggcg gcagaattgg ttgaaaccac gcgcctttac gcgcgcgacg
    28141 tcgccgttat ccagcccgaa tggatagagc aggaagcgcc gcacctcgtc cgctatcatt
    28201 atttcgagcc gcattgggaa caaaaacgcg gcgaagtcgt cgccagcgaa cgcgtgacgc
    28261 tttacggtct gaccgtattg ccgcgccgcc ccgtgcctta cggcaaagtt gcgcccgaag
    28321 aagcacgcga aatctttatc cgcagcgcat tggtggcgca ggaatgcgat ttgaaagcgg
    28381 atttttttgt ccacaacaaa aagctgatta aagaaattac cgaactcgaa cacaaatcgc
    28441 gcaagcaaga cgtattggtc gacgacgaag ccctgtttgc gttttatcac gaacggctgc
    28501 ccaattttta tacggcggac gcggtttcag acgacctgca tcctacaaat ccgcagcaaa
    28561 ctgccccctc ccccgtgggg gagggctggg gagagggcaa aacagttgcc gcacaaacca
    28621 acttttccgc aaccgcagca aaccctctcc ctaaccctct cccacaggag agggagcaga
    28681 gtgccgcagc ttcagcggtt tcaaacgacc tgcatcctgc aaatccccaa caaaccgccc
    28741 cctcccccgt gggggagggc tggggagagg gcaaaacagt tgccgcacaa accaacttct
    28801 ccgcaaccgc agcaaaccct ctcccacagg agggggaaca gagtgccgca gcttcagcac
    28861 tttcagacga ccctcaaccc caaaagcagc cagcatctca aaaaggccgt ctgaaacccc
    28921 tccccctcgc cgacatccgc accttccaag cctggctcaa aaccgccgaa cgcgagaacc
    28981 cgcgcctgct gttcctcagc cgcgacgatt tgatgcaaca cgccgccgca cacattaccg
    29041 aagaacaatt ccccaaattc tggcaaaccg cagacggcaa attcaaactc agctaccgct
    29101 tcgagccgca ccacccgctc gacggcgtta ccctcaccct gccgctcacc gtgctcaacc
    29161 gcatcagccc cgccgccctc gaatggctcg tgcccggtat gttgcgcgag aaaatccagc
    29221 tgctgattaa agcactgccg aagcaaatcc gccgcatttg cgtgcccgta cccgatttca
    29281 ttaccaaatt tctcgaaagc aatcccgacc gccaagcggc catcattccc cagttggcgc
    29341 actttatcgc caaaagcgca ggcgatatgc ggattttcga gcaaatcgac caagacgcat
    29401 gggcggtgca agaattgccc gaacactgct atctgaatct gcgcattatc gacgacggcg
    29461 gacaagagct tgccggcggc cgcaaactgc acgaattgca acaacagctc ggccaagccg
    29521 ccgccaccac cttccgcgac aacacccaag aattcgagcg cgacaacgtt accgcatggg
    29581 acatcggcac cctacccgaa tccatcaaat tcgcacgcgg caaacaacag ctcaccggct
    29641 atctcggtct gcaaaaagaa aaagacggcc gcatcgccct gcgcctgtgt gacaccatcg
    29701 aagccgccga gcaggcacac cgtcaaggcg tcatcgaatt gatgaagctg caattaaaag
    29761 agcaggtaaa agacctgaac aaaggcatcc aaggcttcac ccaagccgcc atgctgctca
    29821 aacacatcaa cgccgacacc ctgcgcgacg acctcaccca agccgtctgc gaccgcgcct
    29881 ttatcggcga agacgagctg ccgcgcaacg aaaaagcctt caaagaacaa atcaaacgcg
    29941 cccgcagccg cctgcccgcc gtcaaagaag ctctcagtcg ttacctgcag gaaaccgccg
    30001 ccgcctatgc cgaactgaac ggcaaactcg gcaaacaccc gctcacccat ctcctaagac
    30061 tacgcctgca aaccctgctt gcccccagct tcgccacccg caccccgtgg gcacaatggc
    30121 cgcgcctccc catctatctc aaagccatga ccctgcgcct cgaaaaatac agcagcaacc
    30181 ccgcccgcga cgcagcccgc gaagccgata tccaagagct ggaacaaatg tggcaggaaa
    30241 aaaccgatag cttggtgaaa caaggattgc ccatttcaga cggccttgca gggtttaaat
    30301 ggatgattga agaattgagg gtgtcgctgt ttgcgcagga attgaagaca ccgtatccgg
    30361 tgtcggtgaa gcggctgatg aaggagtggg agaggttgaa taagtagtga tattatccaa
    30421 tacatttaca ggaaaatttc taacttacat aaaaggtaca actcaatgaa aagcgaaaat
    30481 aattatgaac gtattgttca aaattctaaa aaattccaac actctcagaa gaatgagatg
    30541 cagaaacgca taacagattt gctgcaacaa ctcacaaatg gcattcatga acgcgaccaa
    30601 attatggcgg tttccctact tggtgcgatt gccggacata atactttcct atttggaccg
    30661 ccgggaaccg cgaaaagtct gatttcccgc cgtttggcat gtgcatttga aaatccgcaa
    30721 tactttgaat acttgatgaa ccgtttcagc acacctgaag aagtattcgg acctgtatct
    30781 attaaggcat tgaaagaaga ccgatatctc cgaaaaatcg aaggctattt gccaactgcc
    30841 gattttgcat ttttggatga aatttggaaa tccagtcctg caattttgaa taacctgctg
    30901 accattatca acgagcatat ttttaaaaac ggcgatgaga ggtttaatgt gccacttaaa
    30961 gccctgattg cggcttccaa cgaaattcca cctgaaaatc aaggtttaga ggcactgtat
    31021 gaccgcttta ttatccgtct gcttgtgccg ccgattgaac aagaagagaa cttcaaccgt
    31081 ttgctggata gcaaaccaag cagcgacaaa cctgaaatca gtgaagattt acggattagt
    31141 tatcatgagc ttgccaaatg gcgtgaacaa ctccacaaag tcaggctaag tacagataca
    31201 ttactgatta ttaagtatat cagagaagaa ttagcagccc agtttgataa gttaggcgtt
    31261 tatgtatccg accgacgttg gcaacgtgca gccgtattat taaaggcttc tgctttttgc
    31321 aatggacgca aagaaaccaa tcatagcgat gtgatcttgc tgaaatattg tctgtggaca
    31381 acacctgaaa atcgagagtc agtggaacaa attgtgatga atgccattaa atcctgtggg
    31441 tttgatacag gtattgatct ggctgaatta gatagagaaa aagagagttt ggataaggaa
    31501 ataaataagg aactttatca ttcacaagat gtttatgaga cggttgaaat gagtggaaaa
    31561 aaatattttc cagtacaggc tgttttcaaa aacgtacata atagtcatgc taataaagaa
    31621 cttaagattt atgttccata tagcaaattt cgtagtaaag aaaaatttta tccaatagat
    31681 agtacaggaa atgaaattca agaaattgaa tgtgaatttg atgggcaagg ttgctgtaaa
    31741 ttggaattga aagtgcgggg tggtcactgg aatgagcaat ataagccatt aaaatttaaa
    31801 cccaatatct tatttcacaa aggagataaa aaatcagatg ttaacgaacg tctaattcat
    31861 tcactaaccc aatctatatc tgatattcgc aaacaattga ttgatacaca gaaacaagtt
    31921 gagaaaaaat acgaaaaata ccagcagtac ctgcaaagcc cctttgttgc ccaagcagat
    31981 attgatgttg ctatatcagg tattctagac caaatcgata aactcaattt gcggattaaa
    32041 gactgcgaac gtttggagtc tttatgtcgt taaacagaaa attatccgaa caaataagat
    32101 ggattaaagc ttctctacaa atagattatg cagatttatt taaacagcat ggttcgttaa
    32161 atggacagat tcagcaacgt ttatcagatt ggcaatatca ggccaaactg gctttgttgc
    32221 agaaaaaccc atttatatta catgaagaaa agctaaaaaa acaccaacaa acagaaattt
    32281 ttaatcaaca gtctgttgat gattatcggt atttttgcaa attagcaggc gtgccatttg
    32341 aaaaagaatt ctggcagcag gaattaacac aaagcaaaaa ttcaaaaccc aataaacaga
    32401 atttgccttt gaaattgcta acaggaaaat ggcagcagca attagactat gccaaatctc
    32461 aatggtattt aaagcaactt aatcaattac gacaggaatt tatagataag ttaaaacagg
    32521 aactcgacac tatccgacag cttgcagaac agttagagca atttggtttt gaagcagggc
    32581 tgtggtttga taacagtatc ggcaatttaa gccagcaaaa tattgaagaa atgaaacgct
    32641 ggctgaatta cttgacccaa gataagaatg cccaacagat tgctgaatta ctaggcaaaa
    32701 tgcgccaaat cgaacaatct gaaaaaatcg aacaggtaaa acagactgtt tacacaaaaa
    32761 gcccacaaat tgatgtgaat tcgcgtgaag aaattatcgg attacgttta ggtaaagatt
    32821 tagagtatgt attgccgtct gaattggctt taatggcaga tgaagaaaca tcgactttat
    32881 ttgatttgaa gtttttggaa tccaaattaa tgtgttttga attgcaagga atgacctatt
    32941 gcgatgcccc aactgaaatt atagttgaac aaaaaagcca agaggatgaa aagctcggac
    33001 caatgatttt atgtgtagat accagtggtt caatggttgg tctacctgaa aatattgcca
    33061 aagcaatggc tttattttta ggagcaaaag ctaaaagcga aaaccgttct tgttttgtta
    33121 tcaatttttc cactggaata gaaacttttg aattaacaag taaaacaggg atttccaatt
    33181 tgattgcttt tttacgtcaa tcctttcatg gtggtacaga tgctgcccca gctttacgtc
    33241 atgcgctaaa aatgatggag caagaaatct atcaaaaggc agacttatta atgatttccg
    33301 attttgtgat gaacagctta cctgatgatt tgttggcatc aatcgaaata caacgagaaa
    33361 ccggtaatca gtttaattct ttggttattg gtgatgcttt tatgagtaaa cgcctaaaaa
    33421 cacattttga tcgtgagtgg atatacaatc ctaatgttca gacaattcaa gaattagtac
    33481 agttcaagaa agatattttc aataaacaag ttgtcaactc ataacactat cctactcata
    33541 tgtatttttg gaagatacca ccctatacaa cttggaatcc atacgcagaa tatgtgtgga
    33601 ctttctaaac tactcccctt tccaccctaa aaaaggtcgt ctgaaaccca ttttcagacg
    33661 acctttttcc acttcgcaaa acaagaattc ccacccctct ccccaaacgt cgcccgaacc
    33721 agtaaactcc ccatatttca acaacttctt ggaagccaac catgccccgt atccaccctc
    33781 ctcacctgtt cccgccccat atcgccgaac gcggcctttt gtattttcag cagggcaagg
    33841 ttcgcgatgt ccgaaaaact tccgccgggc gttatc
//
LOCUS       DAXISH010000014        31964 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.014, whole genome shotgun sequence.
ACCESSION   DAXISH010000014 DAXISH010000000
VERSION     DAXISH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 31964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31964
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.014"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(112..858)
                     /gene="fabG"
                     /locus_tag="ACFOV4_000697"
     CDS             complement(112..858)
                     /gene="fabG"
                     /locus_tag="ACFOV4_000697"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HFC7618762.1"
                     /translation="MSTQDLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESG
                     AAAISERLAQWGGEGRVLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRM
                     KEEEWDDIMQVNLKSVFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKA
                     GLIGFSKSMAREVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTALGRFGDAQD
                     IADAVLFLASDQAKYITGQTLHVNGGMLMP"
     gene            complement(920..2485)
                     /gene="guaA"
                     /locus_tag="ACFOV4_000698"
     CDS             complement(920..2485)
                     /gene="guaA"
                     /locus_tag="ACFOV4_000698"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFC7618763.1"
                     /translation="MTQDKILILDFGSQVTQLIARRVREAHVYCELHSFDMPLDEIKA
                     FNPKGIILSGGPNSVYESDYQADTGIFDLGIPVLGICYGMQFMAHHLGGEVQPGNQRE
                     FGYAQVKTIDSELTRDIFDDAPNTLDVWMSHGDKVSKLPDGFAVIGNTPSCPIAMMEN
                     AEKQFYGIQFHPEVTHTKQGRALLNRFVLDICGAQPGWTMPNYIEEAVAKIREQVGSD
                     EVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKMVMDMFARNLGVKVI
                     HVDAEGQFMAKLAGVTDPEKKRKIIGAEFIEVFDAKEKKLTNAKWLAQGTIYPDVIES
                     AGAKTQKAHAIKSHHNVGGLPENMKLKLLEPLRDLFKDEVRELGVALGLPREMVYRHP
                     FPGPGLGVRILGEVKKEYADLLRQADDIFIQELRNTTDENGTSWYDLTSQAFAVFLPV
                     KSVGVMGDGRTYDYVVALRAVITSDFMTAHWAELPYSLLGRVSNRIINEVKGINRVVY
                     DVSGKPPATIEWE"
     gene            complement(2585..4450)
                     /gene="msbA"
                     /locus_tag="ACFOV4_000699"
     CDS             complement(2585..4450)
                     /gene="msbA"
                     /locus_tag="ACFOV4_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005319 - lipid transporter activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006869 - lipid transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A export permease/ATP-binding protein
                     MsbA"
                     /protein_id="HFC7618764.1"
                     /translation="MIEKLTFGLFKKEDARSFMRLMAYVRPYKIRIVAALIAIFGVAA
                     TESYLAAFIAPLINHGFSAPAAPPELSAAAGIISTLQNWREQFTYMVWGTENKIWTVP
                     LFLIILVVIRGICRFTSTYLMTWVSVMTISKIRKDMFAKMLTLSSRYHQETPSGTVLM
                     NMLNLTEQSVSNASDIFTVLTRDTMIVTGLTIVLLYLNWQLSLIVVLMFPLLSLLSRY
                     YRDRLKHVISDSQKSIGTMNNVIAETHQGHRVVKLFNGQAQAANRFDAVNRTIVRLSK
                     KITQATAAHSPFSELIASIALAVVIFIALWQSQNGYTTIGEFMAFIVAMLQMYAPIKS
                     LANISIPMQTMFLAADGVCAFLDTPPEQDKGTLAPQRVEGRISFRNVDVEYRSDGIKA
                     LDNFNLDIRQGERVALVGRSGSGKSTVVNLLPRFVEPSAGNICIDGIDIADIKLDCLR
                     AQFALVSQDVFLFDDTLFENVRYSRPDAGEAEVLSALQAANLQSLIDSSPLGLHQPIG
                     SNGSNLSGGQRQRVAIARAILKDAPILLLDEATSALDNESERLVQQAFERLMENRTGI
                     IVAHRLTTIEGADRIIVMDDGKIIEQGTHEQLMSQNGYYTMLRNISNKDAAVRTA"
     gene            complement(4589..5515)
                     /gene="fabD"
                     /locus_tag="ACFOV4_000700"
     CDS             complement(4589..5515)
                     /gene="fabD"
                     /locus_tag="ACFOV4_000700"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFC7618765.1"
                     /translation="MSFAFFFPGQGSQSLGMMNGFTGQAVVKNTFDEASAILGQDLWA
                     MINGSDAEIIGQTVNTQPIMLAAGVAVYRAYLEAGGKTPAAVAGHSLGEYTALVAAGA
                     LDFADAVKLVRLRAELMQSAVPQGVGAMAAILGLEDEQVKQICAESTQGEVVEAVNFN
                     SPGQVVIAGNTAAVERAMLAAKEAGAKRALPLPVSVPSHCSLMKPAADKLAEALKTVE
                     IKQPQIRVIHNADVAAYDDADKIKDALVRQLYSPVRWTETVNALVSDGIAESAECGPG
                     KVLAGLAKRINKAAACSALTDAGQVAAFIEAH"
     gene            complement(5541..5912)
                     /locus_tag="ACFOV4_000701"
     CDS             complement(5541..5912)
                     /locus_tag="ACFOV4_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFC7618766.1"
                     /translation="MKRQAFFKPIACAAFLSAISLRLPVLGACYAILSLYAFALYGID
                     KRRAVRGKRRIPEHRLLLPALFGGWAGAYLGSRIFRHKTAKKRFVVLFRLTVSGNVLA
                     TLILIDYFVPPELFVKLGQHL"
     gene            complement(5959..6921)
                     /locus_tag="ACFOV4_000702"
     CDS             complement(5959..6921)
                     /locus_tag="ACFOV4_000702"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFC7618767.1"
                     /translation="MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRH
                     IAAENEKTSDLAAEAARRALDATGLDSGEIDLIIVATATPDMQFPSTATIVQQKLGIT
                     NGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFG
                     DGAGAVVLSASDKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKF
                     AVKMLSKIADDVIEEAGYTAAQIDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHG
                     NTSAASIPLALDTGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY"
     gene            complement(6948..7151)
                     /locus_tag="ACFOV4_000703"
     CDS             complement(6948..7151)
                     /locus_tag="ACFOV4_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618768.1"
                     /translation="MPSEACLVFRRHFLRLKQRIGNPALPVHGNLHLKTICIPNHTPI
                     PVSVICTLPVLGNHRFFAYNSRI"
     gene            complement(7171..7586)
                     /locus_tag="ACFOV4_000704"
                     /pseudo
     CDS             complement(7171..7586)
                     /locus_tag="ACFOV4_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7613..7864)
                     /locus_tag="ACFOV4_000705"
     CDS             complement(7613..7864)
                     /locus_tag="ACFOV4_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MafI family immunity protein"
                     /protein_id="HFC7618769.1"
                     /translation="MKTLEKRMKALDKQMMKFGKSLEGRLDARLIESALDYIHYSERF
                     LAFEILCTYIEDFDVRLTEQESREISFINKEFEIESTSD"
     gene            complement(8000..9055)
                     /gene="plsX"
                     /locus_tag="ACFOV4_000706"
     CDS             complement(8000..9055)
                     /gene="plsX"
                     /locus_tag="ACFOV4_000706"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFC7618770.1"
                     /translation="MITLAVDAMGGDQGLAVTVPGATAFLQAHPDVRLIMTGDETQLR
                     QALTAAGAPMERIDICHTTQVVGMDESPQSALKNKKDSSMRVAINQVKEGKAQAAVSA
                     GNTGALMATARFVLKTIPGIERPAIAKFLPSDTDHVTLALDLGANVDCTPEQLAQFAV
                     IGSELVHALHPQKGQPRVGLVNVGTEDIKGTDTVKQTYKLLQNSKLNFIGNIESNGIL
                     YGEADVVVADGFVGNVMLKTIEGAVKFMSGAIRREFQSNLFNKLAAVAALPALKGLKN
                     KLDPRKFNGAILLGLRGIVIKSHGGTDETGFRYALEEAYHEAKSAGLSKIEQGVAEQL
                     AALETAKAVQNENADGL"
     gene            complement(9143..9670)
                     /locus_tag="ACFOV4_000707"
     CDS             complement(9143..9670)
                     /locus_tag="ACFOV4_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase"
                     /protein_id="HFC7618771.1"
                     /translation="MKQKIWYTYDDIHRVIKALAEKIRNADIKYDAMIAIGGGGFIPA
                     RMLRCFLEIPIYAVTTAYYDSDNEGQVTEEVKKVQWLDPVPEALRGKNVLVVDEVDDS
                     RVTMEFCLTELLKEDFGTIGVAVLHEKIKAKAGKIPEGIPYFSGITVEDWWINYPWDA
                     LDIDEHNRLAEAGRG"
     gene            complement(9845..10024)
                     /gene="rpmF"
                     /locus_tag="ACFOV4_000708"
     CDS             complement(9845..10024)
                     /gene="rpmF"
                     /locus_tag="ACFOV4_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFC7618772.1"
                     /translation="MAVQQNKKSPSKRGMHRSHDALTAPALSVDSTTGEVHRPHHISP
                     NGMYRGRKVVKAKGE"
     gene            complement(10058..10561)
                     /locus_tag="ACFOV4_000709"
     CDS             complement(10058..10561)
                     /locus_tag="ACFOV4_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003776445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFC7618773.1"
                     /translation="MSDPNLIDSEIFAAEGQNLQGSFLLEELDERVSSHDYPADRQTK
                     ISFTLTGGRDRLQRLFLDLNVKADMPLICQRCIKPMPFMLDESSRIVLFSNEESLDES
                     MLADEELEGILIEKELDVRTLVEDQILMSLPFSPRHEDCGDNGTLEEVNRDKPNPFAV
                     LAGLKSN"
     gene            10709..11299
                     /locus_tag="ACFOV4_000710"
     CDS             10709..11299
                     /locus_tag="ACFOV4_000710"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFC7618774.1"
                     /translation="MGLELPLILGTSSVFRREQMERLGIAFQAASPDFDETPMLGESA
                     PQTALRLAEGKARSLAGRFPEALIVGADQVAWCDGRQWGKPMNLANAHKMLMHLSGRE
                     IEFYSAVVLLNTVTGRMQRHIDKTVVVMRKLDELHILRYLEREPDAVYCSCALKSEAL
                     GALLIERIESTDPNALIGLPVFRLVDFLKNEGVEVL"
     gene            11346..12071
                     /locus_tag="ACFOV4_000711"
     CDS             11346..12071
                     /locus_tag="ACFOV4_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HFC7618775.1"
                     /translation="MSEGMVSPVLYLIPTPLGTPDTPCLLPHEQQAIVGLTDFVVEAE
                     KTARAHLKHLGVTMPIRELNLQTLNEHTDLKTLPELLKPLQEGRSMGIVSEAGCPAVA
                     DPGANLVALAHKHGFEVRPLVGPSSLLLALMASGANGQNFAFKGYLPSEKNERIQSLK
                     ALEQRSRQQNETQLFIETPYRNDVLLADAVENLHPETRLCTATDLTLPTQSVVSKTVA
                     DWRRMKEMPNLKKRPTIFVMYAG"
     gene            complement(12152..13789)
                     /gene="yidC"
                     /locus_tag="ACFOV4_000712"
     CDS             complement(12152..13789)
                     /gene="yidC"
                     /locus_tag="ACFOV4_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFC7618776.1"
                     /translation="MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQAAQQQAVTA
                     SAEAALAPATPITVTTDTVQAVIDEKSGDLRRLTLLKYKATGDENKPFILFGDGKEYT
                     YVAQSELLDAQGNNILKGIGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKG
                     SYLVNVRFDIANGSGQTANLSADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKV
                     SFSDLDDDAKSGKSEAEYIRKTPTGWLGMIEHHFMSTWILQPKGGQSVCAAGDCRIDI
                     KRRNDKLYSTSVSVPLAAIQNGAKAEASINLYAGPQTTSVIANIADNLQLAKDYGKVH
                     WFASPLFWLLNQLHNIIGNWGWAIIVLTIIVKAVLYPLTNASYRSMAKMRAAAPKLQA
                     IKEKYGDDRMAQQQAMMQLYTDEKINPLGGCLPMLLQIPVFIGLYWALFASVELRQAP
                     WLGWITDLSRADPYYILPIIMAATMVAQTYLNPPPTDPMQAKMMKIMPLVFSVMFFFF
                     PAGLVLYWVVNNLLTIAQQWHINRSIEKQRTQGEVVS"
     gene            complement(13961..14182)
                     /gene="yidD"
                     /locus_tag="ACFOV4_000713"
     CDS             complement(13961..14182)
                     /gene="yidD"
                     /locus_tag="ACFOV4_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFC7618777.1"
                     /translation="MNFLLSKLLLGLIRFYQYCISPLIPPRCRYTPTCSQYAVEAVKK
                     YGAFKGGRLAIKRIARCHPFGGHGHDPVP"
     gene            complement(14247..14612)
                     /gene="rnpA"
                     /locus_tag="ACFOV4_000714"
     CDS             complement(14247..14612)
                     /gene="rnpA"
                     /locus_tag="ACFOV4_000714"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFC7618778.1"
                     /translation="MDYRFGRQYRLLKTDDFSSVFAFRNRRSRDLLQVSRSNGNGLDH
                     PRIGLVVGKKTAKRANERNYMKRVIRDWFRLNKNRLPPQDFVVRVHRKFDRSTAKQAR
                     AELAQLMFGNPATGCGKQV"
     gene            complement(14615..14749)
                     /gene="rpmH"
                     /locus_tag="ACFOV4_000715"
     CDS             complement(14615..14749)
                     /gene="rpmH"
                     /locus_tag="ACFOV4_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003816025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFC7618779.1"
                     /translation="MKRTYQPSVTKRKRTHGFLVRSKTRGGRAVLAARRAKGRKRLAV
                     "
     gene            15041..16597
                     /gene="dnaA"
                     /locus_tag="ACFOV4_000716"
     CDS             15041..16597
                     /gene="dnaA"
                     /locus_tag="ACFOV4_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFC7618780.1"
                     /translation="MTLAEFWPLCLRRLHDILPQGQFAQWIAPLTVGEEGGVWVVYGK
                     NQFACNMLKSQFAGKIEAVREELAAGRSAFVFKPGEGVRYEMAAVESAVEPAEPSLHA
                     VSEEMPVQEVLLDELPSEGSAKSVQAKTAADILAERMKNLPHEPRHTAGSASRPESEV
                     LAKARTDAQRDAEEARYEQTNLSPDYTFDTLVEGKGNRLAAAAAQAIAESPGQSYNPF
                     FLYGSTGLGKTHLVQAVGNELLKNRPDAKVRYMHSDDYIRSFMKAVRNNTYDVFKQQY
                     KQYDLLIIDDIQFIKGKDRTMEEFFYLYNHFHNEKKQLILTCDVLPAKIEGMDDRLKS
                     RFSWGLTLELEPPELEMRIAILQKKAEAAGISIEDEAALFIANLIRSNVRELEGAFNR
                     VGASSRFMNRPVIDIDLARTALQDIIAEKHKVITADIIIDAVAKYYRIKISDVLGKKR
                     TRNIARPRQVAMSLTKELTTLSLPSIGDSFGGRDHTTVMHGIRAVAKLREEDPELAQD
                     YEKLLILIQN"
     gene            16676..17779
                     /gene="dnaN"
                     /locus_tag="ACFOV4_000717"
     CDS             16676..17779
                     /gene="dnaN"
                     /locus_tag="ACFOV4_000717"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFC7618781.1"
                     /translation="MLILQAERDSLLKPLQAVTGIVERRHTLPILSNVLIEGKGGQTK
                     LLATDLEIQIDTAGPEGGAGDFRITTNAKKFQDILRALPAGALVSLDWDDSRLTLKAG
                     KSRFALQTLPAADFPMMNVGEDISATFSLEQERFKTMLSQVQYSMAVQDIRYYLNGLL
                     MQVEGSQLRLVATDGHRLAYAACAIDADLPRAEVILPRKTVLELFKLLNNPDDPIQIE
                     LLDKQVRFQCNGTTIVSKVIDGKFPDFNRVIPLDNDKIFVLSRAELLGALERVSILAN
                     EKFRGARLFLQSGLLSVVCSNNEQEEAREEIEIAYQGGELEVGFNIGYLMDVLRNIHS
                     DDMQLAFGDANRSTLFTVPNNPNFKYIVMPMRI"
     gene            complement(18042..20099)
                     /gene="ppk1"
                     /locus_tag="ACFOV4_000718"
     CDS             complement(18042..20099)
                     /gene="ppk1"
                     /locus_tag="ACFOV4_000718"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HFC7618782.1"
                     /translation="MPEQNRILCRELSLLAFNRRVLAQAEDKNVPLLERLRFLCIVSS
                     NLDEFFEVRMAWLKRENKLHPRRRLDNGKMPSETIADVTEAARSLIRHQYDLFNNVLQ
                     PELAQEGIHFYRRRNWTGAQKKWIESYFDRELLPILTPIGLDPSHPFPRPLNKSLNFA
                     VELDGTDAFGRPSGMAIVQAPRILPRVVPLPSELCGGGHGFVFLSSILHAHVGKLFPG
                     MNVKGCHQFRLTRDSDLTVDEEDVQNLRAAIQNELHDREYGDGVRLEVADTCPSYIRD
                     FLLAQFKLTAAELYQVKGPVNLVRLNAVPDLVNRPDLKFPTHTPGRLKALGKTASIFD
                     LVRQSPILLHHPYQSFDPVVEMMREAAADPDVLAVKMTIYRTGTRSELVRALMKAALA
                     GKQVTVVVELMARFDEANNVNWAKQLEEAGAHVVYGVFGYKVHAKMALVIRREDGVLK
                     RYAHLGTGNYHQGTSRIYTDFGIITADEQITADVNTLFMEITGLGKPGRLNKLYQSPF
                     TLHKMVIDRIARETEHAKAGKPARITAKMNSLIEPTVIEALYRASAAGVQIDLIVRGM
                     CTLRPGVKGLSENIRVRSIIGRQLEHARVYCFHNNGADDTFISSADWMGRNFFRRIET
                     AAPITAPELKKRVIREGLEMALDDNTHAWLMQPDGGYIRAAPAEGESEADLQNDLWTL
                     LGG"
     gene            complement(20268..20711)
                     /locus_tag="ACFOV4_000719"
     CDS             complement(20268..20711)
                     /locus_tag="ACFOV4_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HFC7618783.1"
                     /translation="MPFRLFLGILCDLSMVAPVYAQGQPDAVNAYIQKKKVIVNTSKA
                     ELCFADDRQCHPVLIGVATPKGTFGLTLNSTDKPGYGGEVIGFKQEGDFLFALHRVWN
                     QIPSERRNERIASPSVSDRIMTNGCINVSDAVYEKLRHYFVLEVI"
     gene            complement(20718..21233)
                     /locus_tag="ACFOV4_000720"
     CDS             complement(20718..21233)
                     /locus_tag="ACFOV4_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HFC7618784.1"
                     /translation="MKIKQIVKPGLAVLAAGILSACATKSNVKADGATDNPVFPKPYS
                     VTLDNKRGTFPTYDELDQMRPGLTKDDIYKILGRPHYDEGMYGVHEWDYLFHFHTPGV
                     GIDPENTSGVEDVTTCQYKVIFDKDKFARSFYWNPVFPKDAACPPPAPKAEPQVIIRE
                     IVPAKPKRIRQ"
     gene            21500..24130
                     /gene="leuS"
                     /locus_tag="ACFOV4_000721"
     CDS             21500..24130
                     /gene="leuS"
                     /locus_tag="ACFOV4_000721"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFC7618785.1"
                     /translation="MQEQYQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYP
                     SGKLHMGHVRNYTIGDVLSRFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTY
                     DNIEYMKTQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDP
                     VDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKT
                     MQRNWIGKSRGMTVRFAVSDDSKQGLEGDYAKFLQVYTTRPDTLMGATYVAVAAEHPL
                     AAAAAADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYVVNPLNGDKLEVWIANY
                     VLWGYGDGAVMAVPAHDERDFEFAAKYNLPKKQVIAVGDNAFDANRWQEWYADKENGV
                     LVNSGDLDGLDFQTAFDAVAAKLQSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCE
                     KCGDVPVPADQLPVVLPENVVPDGMGSPLAKMPEFYETACPCCGGAAKRETDTMDTFM
                     ESSWYFFRYMSPKFSDGMVSAEAAKYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEG
                     LVNVDEPFKRLLTQGMVVCETYYRENDKGGKDWINPADVELTFDDKGRPVSAVLKADG
                     LPVVISGTEKMSKSKNNGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAH
                     RFLRRLWRTVYEYLKQGGAVKAFAGSQDGLSKELKDLRHKLHSTIAKVSDDYGRRQQF
                     NTAIAAVMELLNQYDKTDTGSEQGRAVAQEVLEAAVRLLWPIVPHICETLWSELNGAK
                     LWEAGWPTVDEASLVKSEIEVMVQVNGKLRGKITVAADASKADLEAAALATEGAVKFM
                     EGKPAKKIIVVPGRLVNIVV"
     gene            24365..25177
                     /locus_tag="ACFOV4_000722"
     CDS             24365..25177
                     /locus_tag="ACFOV4_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HFC7618786.1"
                     /translation="MASKPFLKWAGGKHKLVPFIEHNLPTPTRKRLIEPFCGSAALSL
                     ALDFEQYLLNDINADLIGLFRILKEEKSGFIDYARSFFISENNSDSRFYELREQFNFS
                     KNLHERSALFIYLNRHAFNGLCRYNSKGVFNVPFGRYKSPYFPQQEMEGFIQKSDRVE
                     LMCGDFQMILSQTDNTDTVYCDPPYAPLSPTASFTTYAKEGFNLDNQIRLAQSAQQIA
                     PDSQGVLISNHDTEFTRDIYSFAILKTIEVQRNIAAKGSSRKKVGELLAIYD"
     gene            25170..25970
                     /locus_tag="ACFOV4_000723"
     CDS             25170..25970
                     /locus_tag="ACFOV4_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HFC7618787.1"
                     /translation="MIDFDKPAEEDAIYQSRLKKIVSDDLVLYNENSLNVMRKILEKY
                     PNGCFDMIFADPPYFLSNDGFSCQNGQMVSVNKGNWDKSKGMAADLEFYEEWLRLCYA
                     LLKPNGTIWVCGTFHNIYLIGYLMQTIGYHILNNITWEKPNPPPNLSCRFFTHSTETI
                     LWAKKNKKAKHTFHYEMMKAQNDGKQMKCVWTFPPPNKAEKTFGKHPTQKPLPLLERC
                     ILSASNIGDLIFDPFMGSGTTGVAALKHGRKFCGCELEEDFFELAKKG"
     gene            25975..26529
                     /locus_tag="ACFOV4_000724"
     CDS             25975..26529
                     /locus_tag="ACFOV4_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618788.1"
                     /translation="MIIGGIGGARTQTGLRFEERTDLRKLFEEIPGYDLRKTYDNAGY
                     EVWFNGELKAYCFKKYEFYRFLKRPGYSINWKDHLSKRLLPDNGLFIIIRDTLFIIEI
                     KFQQTPGSVDEKLQTCDFKRKQYTKLVHSLGWRVEYVYVLNDWFTKPEYKDVLDYIIS
                     VNCHYQFNTIPLRWFGLPDGETNE"
     gene            complement(27404..27715)
                     /locus_tag="ACFOV4_000725"
     CDS             complement(27404..27715)
                     /locus_tag="ACFOV4_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC7618789.1"
                     /translation="MKYKSEALAAIHEMMEGAYNIGAIDKKTMRGFDKSCLTEIKPLS
                     GGDIKAIREKEALSQAAFAIYLNVGKNHVSAWERGVKKPSGAALKLLTIVKNKGIEAI
                     A"
     gene            complement(27712..28079)
                     /locus_tag="ACFOV4_000726"
                     /pseudo
     CDS             complement(27712..28079)
                     /locus_tag="ACFOV4_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582268.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(28883..28968)
                     /locus_tag="ACFOV4_000727"
     tRNA            complement(28883..28968)
                     /locus_tag="ACFOV4_000727"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28932..28934),aa:Leu,seq:gag)
     gene            complement(28982..29332)
                     /gene="secG"
                     /locus_tag="ACFOV4_000728"
     CDS             complement(28982..29332)
                     /gene="secG"
                     /locus_tag="ACFOV4_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFC7618790.1"
                     /translation="MEAFKTLIWIVNIISALAVIVLVLLQHGKGADAGATFGSGSGSA
                     QGVFGSAGNANFLSRSTAVAATFFFATCMAMVYIHTHTTKHGLDFSNVQQTQQAPKPV
                     SNTEPSAPVPQQQK"
     gene            complement(29339..30112)
                     /gene="tpiA"
                     /locus_tag="ACFOV4_000729"
     CDS             complement(29339..30112)
                     /gene="tpiA"
                     /locus_tag="ACFOV4_000729"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFC7618791.1"
                     /translation="MYHQIGMWDQKWVIGNWKMNGRLQNNNSLMHRFRILPTAERVLI
                     GLAAPTVYLLQLHNAMQIVLNNRILTCAQDVSRFPDNGAYTGEVSAEMLADTGTDIVL
                     IGHSERSLYFGEKNEIQRRKMENVLNVGLIPLLCVGESLEEREAGKEHEVIAHQLSIL
                     QGLDTKNIAVAYEPVWAIGTGKVATVEQIADMHAFIYKEILSLCGSDVKIRVLYGGSV
                     KADNAADIFAVPYVDGALVGGASLSYDSFTAIISAAQNA"
     gene            30272..30799
                     /locus_tag="ACFOV4_000730"
     CDS             30272..30799
                     /locus_tag="ACFOV4_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFC7618792.1"
                     /translation="MYATIGDVMHALHFSASDKAALYREVLPQIESVVADETDWVANL
                     ANTAAVLKEAFGWFWVGFYLVDTRSDELVLAPFQGPLACTRIPFGRGVCGQAWAKGGT
                     VVVGDVDAHPDHIACSSLSRSEIVVPLFSDGRCIGVLDADSEHLAQFDETDALYLGEL
                     AKILEKRFEASRQAA"
     gene            30901..31557
                     /locus_tag="ACFOV4_000731"
     CDS             30901..31557
                     /locus_tag="ACFOV4_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HFC7618793.1"
                     /translation="MDFEKARFNMVEQQIRPWDVLDFDVLDALEEIPRELFVDEDLQG
                     LAYADMALPLANGHKMLEPKVVARLAQGLKLTKNDTVLEIGTGSGYATALLAKLAGRV
                     VSDDIDAEQQNRAKAVLDGLSLENIDYVQNNGLTELSAGAPFDAVYVGGAVNLVPEVL
                     KEQLKDGGRMVVIVGRKPVQRALLITRRGDVFEEKVLFDTLVAHLDDKDADPFGGFQF
                     "
     gene            31636..31959
                     /locus_tag="ACFOV4_000732"
     CDS             31636..31959
                     /locus_tag="ACFOV4_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFC7618794.1"
                     /translation="MDIVQLGSAELKAWMDEGRMFCLLDVRTDEETAVCSLPNALHIP
                     MNLIPLRQNELPDDVPLVVYCHHGIRSLHTAMYLADAGFENLYNLQGGIDAWAAEIDG
                     NMMRY"
BASE COUNT         6938 a         7670 c         9293 g         8063 t
ORIGIN      
        1 cttgtgcctg atccgcaggg gcagggcggg gtgtggcgtg tgttcatttt gtttgggaat
       61 gcaaatgccg tctgaaaggg cttcagacgg cattgtcggc acggctgtcc gtcagggcat
      121 cagcatgccg ccgttgacgt gcagcgtctg gccggtaatg tattttgcct gatcggaagc
      181 caagaacaag actgcatcgg caatgtcttg cgcgtcgccg aatctgccca aggcggtttg
      241 ggcggtaaag gtttggcggg tttcttccgg cagggcgcgg gtcatgtcgg tatcgataaa
      301 gccgggggcg acgcagttga cggtaatgcc ccggctgccg acttcgcgcg ccatggattt
      361 ggagaaaccg attaagcctg cttttgccgc ggcatagttg gtttgaccgg cattgcccat
      421 cacgccgacg acggatgtga tgttgatgat acggccggcg cgctgcttca tcatgccgcg
      481 caagacggct ttggaggcgc gaaagacgga tttgaggttg acctgcatga tgtcgtccca
      541 ctcttcttct ttcatacgca tcaggaggtt gtcgcgggtg atgccggcgt tgttgaccag
      601 aatatcgagt ttgccgaacg ttttttcgat gtcggcaatc aggttttcga cggtttcggg
      661 ttcggcggaa tttaatacgc ggccttcgcc gccccattgc gccaaccgct cgctaatcgc
      721 cgccgcaccg ctctcactgg tcgccgtacc gatgactttg gcaccggctg ccgccagtgt
      781 gtcggcaatt gctgcaccga taccgcgcga ggcgcctgtt accaaagcga ttttgccgct
      841 taaatcttgt gtgctcatat tttttccttt tttccgataa tcgaaagact gcgccggacg
      901 gtgcagccct gtttgctggt tattcccact cgatggtggc aggcggtttg ccgctgacat
      961 cgtacaccac gcggttgatg cctttgactt cgttgatgat gcggttggac acgcgtccga
     1021 gcagtgagta aggcaactca gcccaatgtg cggtcataaa gtcgctggtg atgactgcgc
     1081 gcagtgcgac gacgtagtcg taagtgcgtc cgtcgcccat tacgccgacg gatttcacag
     1141 gcaggaacac ggcgaaggct tggctggtca ggtcgtacca agacgtgccg ttttcgtcgg
     1201 tggtgttgcg taattcttga ataaaaatat cgtctgcttg acgcaataag tcggcgtatt
     1261 cttttttcac ttcgcccaag atgcgcacgc ccaaaccggg gccggggaac ggatggcggt
     1321 acaccatttc gcgcggcaga cccaaagcaa cgcccagttc gcgcacttcg tctttaaaca
     1381 agtcgcgcaa cggctcaagc agcttgagct tcatattttc gggcagaccg ccgacgttgt
     1441 ggtgcgattt gatggcgtgg gctttttggg ttttcgcgcc tgcggattcg attacgtcgg
     1501 ggtaaatcgt gccttgcgcc agccatttgg cgttggtgag ttttttctct ttggcatcaa
     1561 atacttcgat aaattccgcg ccgatgattt tgcgtttttt ctcagggtcg gtaacgccgg
     1621 cgagtttcgc cataaactgc ccttcggcat cgacgtgaat cactttcaca cccaagttgc
     1681 gggcgaacat atccatcacc attttgcctt cgttcaggcg caacaaaccg tgatcgacga
     1741 acacgcaggt cagttggtcg ccgatggcgc ggtgaatcag cgcggcggct acggaagagt
     1801 ctacgccgcc tgacaaacct aaaatcactt cgtcgctgcc gacctgttcg cggattttgg
     1861 caacggcttc ttcgatgtag ttcggcatcg tccagcccgg ttgtgcgccg caaatatcca
     1921 agacaaagcg gttcaacagg gcgcggcctt gtttggtgtg ggtaacttcg gggtggaact
     1981 ggatgccgta gaattgtttt tcggcgtttt ccatcatggc aatcgggcag gacggggtgt
     2041 tgccgatgac ggcgaagccg tcgggcagtt tggacacttt gtcgccgtgg ctcatccata
     2101 cgtcgagtgt gttgggcgcg tcgtcgaaaa tatcgcgggt cagttcgctg tcgatggttt
     2161 tgacttgcgc gtaaccgaat tcgcgctggt tgccgggctg cacttcgccg cccaagtggt
     2221 gcgccataaa ctgcattccg tagcagatgc ccaaaaccgg aatgcccaaa tcaaaaatac
     2281 cggtatcggc ctgatagtcg gattcgtaaa cggaattagg gccgccggaa aggatgatgc
     2341 ctttggggtt gaaggctttg atttcgtcca aaggcatatc gaaggaatgc agttcgcagt
     2401 aaacgtgggc ttcgcgcacg cggcgggcaa tcagctgggt aacttgcgaa ccgaagtcga
     2461 ggatgaggat tttgtcttgg gtcataatgg gttttacagt gattgaagat aatcggatgg
     2521 gtcggcggat atagtgccgt ctgaaagggt cggggcgatt ataccatttc ggacggcatt
     2581 ttgtttatgc cgtccggacg gcggcatctt tgtttgagat attgcgtaac atcgtgtagt
     2641 agccgttttg ggacatcagt tgttcgtgtg tgccttgttc gatgattttg ccgtcgtcca
     2701 ttacgatgat gcggtcggcc ccttcgatgg tggtcaggcg gtgggcgacg atgatgccgg
     2761 tgcggttttc catcaggcgt tcgaacgctt gttggacgag gcgttcggat tcgttgtcta
     2821 atgcgctggt ggcttcgtcc aataataata tcggcgcgtc tttcaaaatg gcgcgggcga
     2881 tggcgacgcg ttgccgctgt ccgccggaca agttgctgcc gttcgatccg atgggctggt
     2941 gcagtccgag cggggagctg tcaatcaggc tttgcaggtt ggcggcttgg agggcggaca
     3001 ggacttcggc ttcgcctgcg tcgggacggc tgtatcggac gttttcaaac agggtgtcgt
     3061 caaacaggaa tacgtcttgg gagacgaggg cgaattgggc gcgcaggcag tcgagtttga
     3121 tgtcggcgat gtcgataccg tctatgcaga tgttgccggc agacggttcg acaaagcggg
     3181 gcagcaggtt gacgacggtg gatttgccgc tgccggaacg tccgaccagg gcgacgcgtt
     3241 cgccttgtct gatgtcgagg ttgaagttgt cgagggcttt gatgccgtcc gaacggtatt
     3301 cgacatcgac gttgcggaag ctgatacgcc cttcgacacg ctgcggcgcg agcgtgcctt
     3361 tgtcctgttc gggcggggtg tcgagaaatg cacatacgcc gtcggcggcg aggaacatcg
     3421 tctgcatagg gatgctgatg ttggcaaggc ttttgatggg tgcgtacatt tgcagcatcg
     3481 cgacgatgaa tgccataaat tcgccgatgg tggtgtagcc gttttggctt tgccacaggg
     3541 cgatgaagat gacaacggcg agggcaatcg aggcaatcag ttcgctgaac ggggaatgtg
     3601 ccgccgttgc ctgcgtgatt tttttgctga ggcggacgat ggtgcggttg accgcgtcaa
     3661 accggtttgc cgcctgcgcc tgcccgttga acagcttgac gacgcggtgt ccctgatggg
     3721 tttcggcaat cacgttgttc atcgtgccta tgcttttttg cgagtcggaa atgacgtgct
     3781 tcagacggtc gcggtagtag cgcgagagca gggagagcag ggggaacatc aggacaacga
     3841 tgaggctgag ctgccagttg aggtaaagca ggacgatggt caggccggta acgatcatcg
     3901 tgtcgcgcgt gaggacggtg aagatgtcgc tggcgttact gaccgactgt tcggtcaggt
     3961 tgagcatatt catcagtacg gtgccggacg gcgtttcctg atggtagcgg gaggaaaggg
     4021 tcagcatttt ggcaaacata tctttgcgga ttttgctgat ggtcatcacg gagacccaag
     4081 tcatcagata ggtgctggta aagcggcaga tgccacggat gacgacgagg atgatgagga
     4141 agagggggac ggtccagatt ttgttttccg tcccccaaac catataggta aactgttcgc
     4201 gccagttttg cagggtggaa atgatgccgg cggcggcaga cagctcgggc ggcgcggcag
     4261 gtgcggaaaa gccgtggtta atcagggggg cgatgaaggc ggcaaggtag ctttcggtgg
     4321 cggcaacgcc gaaaatggca atcagggcgg caacgatgcg gattttgtag gggcggacgt
     4381 acgccatcag gcgcataaag ctgcgcgcgt cttctttttt aaacagtccg aaagtcagtt
     4441 tttctatcat atcggtaggg cgggaactgc aacggcagcc gctgtcggtg gtttggtcgt
     4501 catcaattat agcgcaaata tgcggctgtt tgccgttcgg acgtgaaaag cagcctgaag
     4561 agggcaggct gctttttgcg gaacgaagtc agtgcgcttc gataaaggcg gcaacctgtc
     4621 cggcatcggt cagtgcgctg cacgcggcgg ccttgttgat gcgttttgcc aagcccgcca
     4681 acactttgcc cgggccgcat tcggcggatt cggcaatgcc gtctgaaaca agggcgttga
     4741 cggtttctgt ccagcgtacg gggctgtaaa gctggcggac gagcgcgtct ttgattttgt
     4801 cggcatcatc gtaggcggca acgtcggcgt tgtggatgac gcggatttgc ggctgcttga
     4861 tttcaacggt tttcagggct tcggcgagtt tgtcggcggc gggtttcatc aggctgcaat
     4921 gggaaggtac ggacacgggc agcggcaggg cgcgtttggc gccggcttct ttggcggcaa
     4981 gcatagcgcg ctcgacggcg gcggtattgc ctgcaatcac gacttgtccg ggcgagttga
     5041 agttgacggc ttcaaccact tcgccttgtg tggattcggc gcaaatttgt tttacctgtt
     5101 catcttccaa gccgagaatc gccgccattg cgcccacgcc ttgcggtacg gcagactgca
     5161 tcagttcggc gcgcaggcgc acgagtttga ccgcgtcggc aaaatccaat gcgccggcgg
     5221 caacgagtgc ggtatattcg ccgaggctgt gtccggcaac ggcggcaggc gttttgccgc
     5281 ccgcttccaa ataggcgcgg taaacggcaa cgccggcggc gagcatgatg ggttgggtat
     5341 tgacggtttg accgatgatt tcggcatcgc taccgttaat catcgcccac aagtcttgac
     5401 ccaatatggc ggatgcttcg tcaaatgtgt ttttgacgac ggcctgccct gtaaagccgt
     5461 tcatcatgcc gaggctttga gaaccttgtc cgggaaagaa gaatgcaaaa gacatggtat
     5521 tcctttgttt ggttggattg tcagagatgt tgcccgagtt tgacaaaaag ttcgggcgga
     5581 acgaaataat caatcaggat gagggtcgcc aggacattac ctgaaacagt cagacggaac
     5641 agcacaacaa aacgcttttt cgccgtttta tgcctgaata tcctgctgcc caagtatgcg
     5701 cccgcccaac cgccgaacaa ggcaggcagc agcaggcggt gttcgggaat gcggcgtttt
     5761 ccccgcacgg cacgccgttt gtcgatgccg taaagtgcaa acgcatagag ggacaatatt
     5821 gcgtaacacg cgcccaatac ggggaggcgc agcgaaatgg cagacagaaa tgccgcacac
     5881 gcaattggtt tgaagaaagc ctgccgcttc atgatatggg aaataccgtc tgaaaacctg
     5941 cttcagacgg catggtattc aatattgcag caataccgcg ccccacgcga aaccgccgcc
     6001 gatgccttcg agcagcaggt tttgaccgcg tttgatttgt ccgctgcgga tgcccgtatc
     6061 caaagccagc ggaatcgatg cggcggatgt gttgccgtgg tcttggacgg tcaggacgac
     6121 tttgtccata ctcaaaccta aatgtttcgc ggtcgattcg ataatgcggc ggtttgcctg
     6181 atgcggcacg atccagtcga tttgagcggc ggtataaccg gcttcttcga taacgtcatc
     6241 ggcgattttg gacagcattt tgacggcaaa cttgaacacg ccgggaccgt ccatcgaaat
     6301 gtacggcgaa ccggaaactt tgccgcaggc gatttgcccg gggacgttta agagtttcag
     6361 ataattgccg tcggctttga gtttgctgtg gatgatgccc ggtttgtcgg acgcgcttaa
     6421 aaccaccgcg cccgcaccgt cgccgaacaa tacgcaggtt gtgcggtcgt tccagtctac
     6481 aatgcgactg aaggtttccg cgccgatgac cagcgcgttt tttgccatgc cgcttttgat
     6541 gtaggcgttt gccgtggtca gcgcgtacat aaagcccgca cacaccgcct gtacgtcaaa
     6601 cgcggggcag ccgttggtga tgcccagttt ttgttggacg atggtggcgg tagaaggaaa
     6661 ctgcatatcc ggcgttgccg tcgccacaat aattaaatcg atttcgccgc tgtctaatcc
     6721 ggttgcatcc agtgcgcggc gggctgcttc ggcggcaaga tcgctggttt tctcattttc
     6781 ggctgcaata tggcggaact tgatgcccgt acgcgcggta atccactcgt cagaggtatc
     6841 taccttttgg gcaaggtcgt cattgctgac gcggttggcg ggaagatagc tgcccgtgcc
     6901 ggaaattttt gcatactgca tgggaacggc ctttttagag agttggttca gattcggcta
     6961 ttgtaagcga aaaaccgatg attgcccaat acgggcaggg tgcaaatgac ggaaacaggg
     7021 atgggggtgt ggtttgggat acagatggtt ttcagatgca gattgccgtg gacaggcagg
     7081 gcggggttgc cgatacgctg ttttaagcga aggaaatgcc gtctgaaaac caaacatgct
     7141 tcagacggca ttttgattgt tggttttcca tcaaattatt ggtgccggtg tttgtttttg
     7201 tatcataaat tcagaaatta tattttgaat tgtagaaata tttttagaga tatgctcaat
     7261 agggtaggaa tctcccaaga tttcccttgc cttcccgctg taattttctg ttttaaggtt
     7321 tttgacttca atatccccgt cttctaaaat tgtttgaatc attggcaaat aatatccttt
     7381 ttcaaaatag atagttaatt cggtatcgcc aaattccggc tcggggatga ttctgaaaac
     7441 aaggacgccg gcttttttct caaaatttga tacggaaaaa agtgattgat ttccctaatg
     7501 tcaggatttt ccaaaacggg gatttggatt cgctctccgt tgtctgccat aaaaaatccg
     7561 ccaaaaacga ccgtcgatgt tttcatgttt atcaacccat tggctttatt ggttaatcgg
     7621 acgtgctttc tatctcaaat tccttgttga taaaagaaat ttcccgggat tcttgttccg
     7681 tcagccggac atcgaaatct tcgatataag tacacaggat ttcaaaagcc aaaaaacgtt
     7741 ccgaataatg aatataatcc aatgcggatt caatcagacg ggcatcaagc ctgccttcaa
     7801 gggattttcc gaacttcatc atctgtttgt ctagagcttt catccgtttt tctaatgtct
     7861 tcatttttca aatactcctt attttacagg gaagtatttg ggaagtgccg gacaggcgca
     7921 tcgccgtccg cgcccgcagg tttggtgcgg gcggatgccg tctgaaaggg gcgggggcgt
     7981 tcagacggca tcgtgtgtgt tacagaccgt cggcattttc gttttggacg gctttggcag
     8041 tttcgagtgc ggcgagttgt tcggcaacgc cttgttcgat tttggaaagg ccggcggact
     8101 tggcttcgtg gtaggcttct tcgagtgcgt agcggaaacc ggtttcgtct gtgccgccgt
     8161 ggcttttgat gacgatgccg cgcagcccga gcaggatggc cccgttgaat ttgcgcggat
     8221 cgagtttgtt tttcagccct ttgagggcgg gtagggcggc aacggcggca agtttgttga
     8281 acaggttgct ttggaattcg cggcggatgg ctccgctcat gaatttgacc gcgccttcga
     8341 tggttttgag catgacgttg ccgacaaagc cgtcggcgac gacgacatct gcttcgccgt
     8401 acaggatgcc gttgctttcg atgttgccga taaagttgag tttgctgttt tgcagcagtt
     8461 tgtaggtttg tttgacggtg tccgtacctt tgatgtcttc cgtgccgacg ttgaccagcc
     8521 cgacacgcgg ctgtcctttt tgaggatgga gtgcgtggac gagttcgctg ccgataacgg
     8581 caaattgggc gagctgttcg ggcgtgcagt cgacgtttgc gccgaggtcg agggcgaggg
     8641 taacgtggtc ggtgtcggaa ggaaggaatt tggcgatggc ggggcgttcg atgccgggaa
     8701 tggttttgag gacgaaacgt gcggttgcca tgagtgcgcc cgtgttgcct gcggatacgg
     8761 cggcttgggc tttgccttct ttaacttggt tgatggcaac gcgcatggag gagtcttttt
     8821 tgttctttag ggcggactga ggggattcat ccatgccgac aacttgggtg gtatggcaga
     8881 tgtcgatgcg ttccatcggt gcgcctgccg cggtcagggc ttggcgcagt tgcgtttcgt
     8941 cgccggtcat aatcaggcgg acatcggggt gtgcttggag gaatgcggtt gcgccgggta
     9001 cggtaacggc aagtccttgg tcgccgccca tggcatctac ggcaagtgta atcatagggt
     9061 tctccggtag gttttcggtc tgcggcaggg gtcgtgcggg cttcagacgg catcggttcg
     9121 gaaaatatgc cgtctgaaag ggtcagcctc ggccggcctc ggcaaggcgg ttgtgttcgt
     9181 cgatgtcgag tgcgtcccac ggatagttga tccaccagtc ttctacggtg atgccgctga
     9241 aatagggaat gccttcgggg attttgcctg ctttggcttt gattttttcg tgcagtacgg
     9301 cgacgccgat cgtaccgaag tcttctttga gcagctctgt caggcaaaat tccatggtta
     9361 cgcggctgtc gtccacttca tcgacgacga gtacgttttt gccccgcagg gcttcgggaa
     9421 cggggtcgag ccattggact tttttgactt cttctgtaac ctgtccttcg ttgtcgctgt
     9481 cgtaataggc ggtggttacg gcataaatcg gaatttccag aaaacagcgc agcatacgtg
     9541 ccggaataaa gccgccgccg ccgatggcaa tcatggcatc gtatttgatg tcggcgttcc
     9601 ggattttttc tgccaatgct ttgatgacgc ggtggatgtc atcgtaggtg taccagattt
     9661 tctgtttcat cggaatttcc ttggtggttg gggcttttgg aatattttca cgggttatta
     9721 tacggaacgc tttgcccctg tgtgttgacg tatggcgaaa gtttggacgg atggtgcgtc
     9781 caatgcaaaa aaagccagta attgcatggc aatgttctgg ctttttcagt cagtcgaata
     9841 gggattattc gcctttggct ttgaccactt tgcggccgcg gtacataccg ttgggggaaa
     9901 tgtggtgcgg gcggtgtact tcgccggttg tgctgtcgac agacagtgcg ggcgcggtca
     9961 gcgcgtcgtg cgaacggtgc ataccgcgtt tggaagggga ttttttgttt tgttgaacgg
    10021 ccatttcaag ctcctagata aataaactgt gtcctaatca attgcttttc aaacctgcca
    10081 aaacagcaaa ggggttgggt ttgtcccgat tgacttcttc cagtgtccca ttgtcgccgc
    10141 agtcttcgtg tcgcggcgaa aagggcaggg acatcaggat ttggtcttct accaatgtgc
    10201 gcacgtcgag ttctttttca atcagtatgc cttcgagttc ttcgtcggca agcatggatt
    10261 cgtccaagga ctcttcgttg gaaaacagga cgatacggct gctttcatca agcatgaacg
    10321 gcatgggttt gatacatctc tggcaaatca ggggcatatc ggctttgacg ttcaggtcga
    10381 ggaacaggcg ttgcagccgg tcgcgaccgc cggtcagtgt aaacgatatt ttggtctgcc
    10441 tgtcggcggg ataatcgtgc gaactgacgc gttcatccaa ttcttccagc agaaaactgc
    10501 cttgcaggtt ctgcccttcg gcggcaaaaa tttccgagtc aatcaaatta gggtctgaca
    10561 taaacgggat atgatataat ttagatgttc taacgtcaat atttttaaga aaaatgttgc
    10621 ggtacgccga aggcgggtat ccgtgtttcg gcgcatggct ggattttact gccccttcgg
    10681 gcgtgttttc aacggtaagg aggatgggat gggtttggaa ctgcctttga ttttgggtac
    10741 gagttcggtt ttccgccgcg aacagatgga aaggctcggc attgcctttc aggcggcgtc
    10801 ccccgatttt gacgaaacgc cgatgttggg ggaatccgcc cctcagacgg cattgcgcct
    10861 tgccgagggt aaggcgcggt cgttggccgg gcgtttccca gaggcgttga ttgtcggtgc
    10921 ggaccaggtg gcgtggtgcg acggcaggca gtggggcaag ccgatgaacc ttgctaatgc
    10981 gcacaagatg ttgatgcatt tgagcggcag ggagattgag ttttacagcg cggtcgttct
    11041 gctaaatacg gttacgggca ggatgcagcg gcatatcgat aagacggtgg tcgtgatgag
    11101 gaagttggac gagctacaca tcctccgcta tttggagcgc gagcctgatg cggtttattg
    11161 ctcgtgtgcg ttgaagagcg aggctttggg tgcattgttg atcgaaagga ttgagagtac
    11221 cgatccgaat gctttaatcg gtttgccggt tttccgtctg gttgattttt tgaaaaatga
    11281 gggcgtggag gttctgtaac tgcccgttta tgccgtctga agggttcaga cggcattttt
    11341 aaccgatgag tgagggaatg gtgtctcctg ttttgtattt gattcctacg cctttgggta
    11401 cgcctgacac gccgtgcctg ttgccgcatg aacaacaggc gattgtcggg ctgacggatt
    11461 ttgtcgtgga agcggaaaaa acggcgcgcg cgcatttgaa acatttgggc gtgacaatgc
    11521 ctatccgcga actgaatttg caaacgctga acgaacacac ggatttgaag actttgccgg
    11581 aattgctgaa acctttgcaa gaagggcgca gtatgggcat tgtcagcgag gcgggttgcc
    11641 cggctgtggc tgatccgggt gcgaatttgg tggcattggc gcataaacac ggttttgaag
    11701 tacggccttt ggtcggtccg tccagcttgt tgctggcgct gatggcttcg ggtgcgaatg
    11761 ggcagaactt tgcgtttaag ggttatttgc cgtctgaaaa aaatgagcgg attcagagtt
    11821 tgaaggcttt ggaacaacgt tcgcgccagc agaatgaaac gcagctgttt atcgaaacgc
    11881 cgtatcgcaa cgatgtgttg ttggcggatg cggtggaaaa cctgcatcct gaaacgcgct
    11941 tgtgcacggc tacggatttg acgttgccga ctcagtcggt ggtcagtaaa acggttgcgg
    12001 attggcgcag gatgaaggaa atgcccaatc tgaaaaaacg cccgacgatt tttgtgatgt
    12061 atgcaggttg aagatttccg ccccgatagg gggtgaacaa taaaaatgcc gtctgaacag
    12121 gtttcagacg gcatttttca tgctgcggca tttaggaaac gacttcgcct tgggtgcgtt
    12181 gtttttcgat gctgcggttg atgtgccatt gctgggcgat ggtcaggagg ttgttgacta
    12241 cccagtacaa taccagaccg gcagggaaga agaagaacat gacggagaaa accaacggca
    12301 tgattttcat cattttcgcc tgcatcgggt cggtcggcgg cgggttcaga taagtttggg
    12361 cgaccatcgt tgccgccata atgatgggca ggatgtagta ggggtcggcg cggctgaggt
    12421 cggtaatcca acccagccaa ggtgcctggc gcaattctac ggaggcgaac aatgcccaat
    12481 acaatccgat gaagacgggg atttgcaaca gcataggcag gcagccgccc agcgggttga
    12541 ttttctcgtc tgtgtaaagc tgcatcatcg cctgttgttg cgccatgcgg tcatcgccgt
    12601 atttctcttt gattgcctgc agtttgggcg cggcagcacg cattttcgcc atcgaacggt
    12661 aggacgcgtt ggtcaatgga tacagtacgg ctttgacgat gatggttaaa acgataatcg
    12721 cccagcccca gttgccgatg atgttgtgca gttggttcag gagccagaag agcggggaag
    12781 cgaaccagtg tactttgccg tagtctttgg ccagttgcag gttgtcggcg atgtttgcga
    12841 taacggatgt ggtctgtggg ccggcgtaga ggttgatgga ggcttcggct ttcgcgccgt
    12901 tttggatggc ggctaaaggc acgctgacgc tggtgctgta cagcttgtcg ttgcggcgtt
    12961 tgatgtcgat acggcagtcg ccagcggcgc aaacgctttg tccgcctttg ggttggagga
    13021 tccaggtgga catgaagtgg tgttcaatca tgccgagcca gccggtcggg gttttgcgga
    13081 tgtattcggc ctcggatttg ccggatttgg catcgtcgtc caagtcggag aagctgactt
    13141 tttggaagtt gccttcaggg gtataaacaa cagggccgac gtaagagtgg gtaaagtagc
    13201 cttgaccctc gggttcgctg tggtcgcgga cgatgcggta gtccgcgctc aggttggcgg
    13261 tttgaccgct gccgttggcg atgtcgaagc ggacgttgac cagatagctg cctttggtga
    13321 aagtataaac tttgtcgatt ttcagaccgc gtgtttcagg cgcgctcagg cggacttcaa
    13381 ctttgtcgcc ttccaagctg tactgttttt tcggtgcgct aaagccgatg ccttttagaa
    13441 tgttgttgcc ctgcgcgtcc aaaagttcgg attgggcgac gtaggtgtat tctttgccgt
    13501 cgccaaacag gatgaacggt ttattttcgt cgccggttgc tttgtatttg agcagggtca
    13561 gccggcgcag gtcgccgctt ttttcatcaa tgacggcttg aaccgtgtcg gtcgttacgg
    13621 taatcggcgt tgcgggcgcg agcgcggctt cggcggaagc ggttacggcc tgttgttgtg
    13681 ctgcctgttg gggcgcgggg acgggcttcg gagtggggaa catcttttcc catccgatca
    13741 taatcaccag tgcgatggcg aaaaacgccg tgagtctttt aaaatccata agagtttcct
    13801 gaatggtcgg aaatgccgca ggttgcgtgt tccgatagac ggggaataag ggtgggcttc
    13861 atacccgacg gtcgtgccgc cagcccgaag tttcagacgg cattatatag aaaccgatgg
    13921 gaaataaaag gaaagcgtgc aatttgaata ttgcgtcggg tcagggaacg gggtcgtgtc
    13981 cgtgtccgcc gaaagggtgg cagcgtgcaa tgcgcttgat ggcgagccgg ccgcctttga
    14041 atgcgccgta ttttttgacc gcttcgaccg cgtattgcga acaggtcggc gtataacggc
    14101 agcgcggcgg aatcagcggg ctgatgcaat attggtagaa ccgtatcagt cccagcagga
    14161 gtttggacaa tagaaagttc atcgggatgt tccttgtatg ggaaacccgt tgccgtctga
    14221 accttgcctg cagagtaccg ttctaatcat acctgtttcc cgcatccggt tgcggggttg
    14281 ccgaacatga gttgtgccag ttccgccctt gcctgttttg cggtagacct gtcgaattta
    14341 cggtggacgc gcacgacgaa atcttgcggc ggcagccggt ttttgttcaa tctaaaccag
    14401 tcgcggataa cgcgcttcat ataatttcgt tcgttggcgc gtttggcggt ttttttgccg
    14461 accaccagac cgatgcgggg atggtccagc ccgttgccgt ttgaacgcga aacttgcagc
    14521 aggtcgcggc tgcggcggtt tctgaatgca aaaacggatg aaaaatcatc cgtttttaac
    14581 aagcggtact gccttccgaa gcggtagtcc aaaattatac cgctaggcgt ttgcggcctt
    14641 tggcgcggcg tgcagccaat actgcgcggc cgccgcgtgt tttggagcgc accaggaagc
    14701 cgtgggtgcg tttgcgtttg gtaacggaag gttgataagt gcgtttcatg atgtttccta
    14761 aaatagaatg ggtagataat taaaccgtga attacactcc aatttgccgc ttttgtcaat
    14821 caatatagaa actttgcagg aggattgccc gattgcctgc ggatttctgc cgcctttctg
    14881 tggataaatt tttgcacggg ttgtggataa aatattcgtg agtcggtata atcgggcagt
    14941 cgcgttttga accgatgcgc gttcaacaga tttgttttct ttttgaaaat attatatttt
    15001 ctttgttttc gatttcattt ttaccgattc gagcctatcc atgacattag cagagttttg
    15061 gccgctgtgc ctccgccgtc ttcacgatat cttgcctcaa gggcagtttg cgcaatggat
    15121 tgcgcccctt accgtcggtg aggagggtgg cgtatgggtg gtgtacggca agaaccagtt
    15181 tgcctgcaat atgcttaaga gccagtttgc cgggaaaata gaagcggtga gggaagagtt
    15241 ggctgctggc cgttccgcct tcgtattcaa accgggagaa ggcgtgcgtt atgagatggc
    15301 ggcggttgaa agtgctgtcg aacctgctga gccgtccttg catgcggtgt cggaggaaat
    15361 gcccgtgcag gaggttctgt tggacgagct gccgtctgaa gggtctgcca aatccgtaca
    15421 ggcgaaaacg gcggcggata ttttggcgga acgtatgaaa aacctcccgc atgagccgcg
    15481 ccatactgcc gggtctgctt cccgtccgga atcggaggta cttgcgaaag cgcggacgga
    15541 tgcgcagcgt gatgcggaag aggcgcgtta cgaacaaacc aacctgtctc cggattacac
    15601 atttgatacg ttggtagaag gcaagggcaa ccgccttgcg gcagctgccg cgcaggcgat
    15661 tgcggaaagt ccgggacaga gttataaccc gttcttcctc tatggcagta cgggtttggg
    15721 taaaacccac cttgtgcagg cggtcggcaa cgaactgttg aaaaaccgtc ccgatgccaa
    15781 agtgcgctat atgcattcgg acgactatat ccgcagcttt atgaaggcgg ttcgcaacaa
    15841 tacctacgac gtgttcaagc agcaatacaa gcaatacgac ctgctgatta tcgacgacat
    15901 ccagttcatc aaaggcaaag accgtacgat ggaggaattc ttctatctgt acaatcattt
    15961 ccataacgag aaaaaacagc tcatcctcac ttgcgatgtt ttacccgcca aaatcgaagg
    16021 tatggacgac cgcctcaaat cccgtttttc atggggactg actttggaac tcgagccgcc
    16081 cgaattggaa atgcgtatcg ccattttgca gaaaaaggcg gaagcggcgg gcatcagtat
    16141 tgaagacgaa gccgcgctgt tcattgccaa tctgatccgt tccaacgtgc gtgagcttga
    16201 aggcgcgttc aaccgcgtcg gagcgagcag ccgctttatg aaccgtcccg tcatcgacat
    16261 cgatttggcg cgtaccgctt tgcaggacat tattgccgag aagcacaaag tcatcaccgc
    16321 cgatattatt attgatgccg ttgcgaaata ttaccgcatc aaaatcagcg atgtgctcgg
    16381 taagaaacgg acacgaaaca ttgcccgtcc gcgccaggtg gcgatgagcc tgaccaaaga
    16441 actgaccact ttgagcctgc cgtctatcgg cgattcgttc ggcggacgcg accatacgac
    16501 cgttatgcac ggcatcaggg cagtggcgaa actgcgcgaa gaagatccgg aattggctca
    16561 ggattatgaa aagctgctga ttctgattca aaactgatgg aaaacgtttt cagacggcat
    16621 gatattgccc atgccgtccg aagggtaaaa aatccaaccg atttaaggag cgaaaatgtt
    16681 gattttacaa gccgaacgcg acagcctgct caagccgctg caagccgtta ccggcatcgt
    16741 cgaacgccgc cacaccctgc ccatcctgtc caacgtcctg attgagggaa aaggcggtca
    16801 gaccaaactc ttggcaaccg atttggaaat ccaaatcgac actgcgggtc ccgagggcgg
    16861 cgcgggcgac ttccgcatca ccaccaatgc caagaaattt caggacattt tgcgcgcgct
    16921 gcctgccggt gcgctggtgt cgctggattg ggacgacagc cgtctgacgc tgaaggcggg
    16981 caaatcgcgt tttgccctgc agaccctgcc tgccgccgat tttccgatga tgaatgtcgg
    17041 cgaggacatc agcgcgactt tctcgctgga gcaggagcgt ttcaaaacca tgctgtcgca
    17101 agtgcagtac agcatggcgg tgcaggacat ccgctattat ctcaacggtc tgctgatgca
    17161 ggttgagggc agccagttgc gccttgtggc gaccgacgga caccgccttg cctatgcagc
    17221 ctgcgcgatt gatgcggatt tgccgcgcgc cgaagtgatt ttgccgcgca aaacggtgct
    17281 ggaactgttc aaactgttga acaaccccga cgatccgatt caaatcgagc tgctggacaa
    17341 acaggtgcgt ttccaatgca acggcacgac catcgtcagc aaggttatcg acggcaaatt
    17401 ccccgatttc aaccgcgtga ttcctttgga caacgacaag attttcgttt tgtcccgtgc
    17461 cgaacttttg ggcgcgctgg aacgtgtgtc cattcttgcc aacgaaaaat tccgtggcgc
    17521 gcgcctgttc ctgcaatccg gcctgttgag cgtcgtgtgc agcaacaacg agcaggaaga
    17581 agcgcgcgaa gaaatcgaga ttgcctatca gggcggcgaa ctcgaagtcg gtttcaatat
    17641 cggctatctg atggacgtgt tgcgcaacat ccattccgac gatatgcagc ttgccttcgg
    17701 cgatgccaac cgctcgacgc tgtttaccgt gccgaacaat ccgaatttca aatatattgt
    17761 gatgccgatg cggatttgac ggttttccgg agcacgatgc ccgtattgga gatatgcccc
    17821 gaaccgtgca gacggattcg gggttttgtt cggctgtcgg aaaggcaatg ccgtctggaa
    17881 tgcggcggat tggggttggg agcgtatagg ggaagtgctt atgcggaaat ggcgaaggtg
    17941 tgtttttgac tccggtccgc cctgtttaga ttgctgtaaa accatgccgt ctgaaacgga
    18001 aaggtttcag acggcatggt ttttgattgg ggcggtgcgg ttcagcctcc gagcagtgtc
    18061 cacaaatcgt tttgcagatc ggcttcgctt tcgccctcgg cgggcgcggc gcggatatag
    18121 ccgccgtcgg gctgcatcag ccatgcgtgg gtgttgtcgt ccagtgccat ttccaaacct
    18181 tcgcggatga cgcgtttttt gagttcgggc gcggtaatcg gcgcggcggt ttcgatgcgg
    18241 cggaagaagt tgcgccccat ccaatccgcg ctggagataa aggtatcgtc cgcgccgttg
    18301 ttgtggaagc aatacacgcg cgcgtgttcg agctgcctgc cgatgatgga gcggacgcgg
    18361 atgttttcgg acaagccttt tacacccggg cgcaaggtgc acataccgcg cacaatcaaa
    18421 tcgatttgta cgcctgccgc gcttgcccga tacagggctt cgatgacggt cggttcgatg
    18481 agcgaattca tcttggcggt aatccgcgcc ggtttgccgg cttttgcgtg ttcggtttcg
    18541 cgtgcgatgc ggtcgataac cattttgtgc agggtaaacg ggctttggta gagtttgttc
    18601 agccgcccgg gtttgcccaa gcctgtgatt tccataaaca atgtgttcac atcggcggtg
    18661 atttgttcgt cggcggtaat gatgccgaag tcggtgtaga tgcgcgatgt gccttggtgg
    18721 tagttacccg tgccgaggtg ggcgtaacgc ttgagtacgc cgtcttcgcg gcggatgacc
    18781 agtgccatct tggcgtggac tttgtagccg aacacgccgt acacgacgtg cgcgcccgcc
    18841 tcttcgagct gcttcgccca gttgacgttg ttggcttcgt caaaacgcgc catcagttcg
    18901 acgacgacgg ttacttgttt gccggcgagt gccgccttca tcagggcgcg gacgagttcg
    18961 gaacgcgtgc cggtgcggta aatcgtcatt ttgacggcaa gcacgtcggg gtcggcggca
    19021 gcttcgcgca tcatttcgac aacggggtcg aacgattggt aggggtggtg cagcaggatg
    19081 ggcgattggc gcaccaaatc gaatatggac gcggttttgc ccaaggcttt cagtctgccc
    19141 ggcgtgtgtg tgggaaattt caaatcgggg cggttgacta ggtcggggac ggcgttgagg
    19201 cgcacgaggt tgaccgggcc tttgacctga tagagttcgg cggcggtcag tttgaattgc
    19261 gcgagcagaa agtcgcggat gtaggaggga caggtgtcgg cgacttcgag ccgcacgccg
    19321 tcgccgtatt cgcggtcgtg cagttcgttt tgaatggcgg cgcggaggtt ttgtacgtct
    19381 tcttcgtcaa cggtcaagtc gctgtcgcgc gtgaggcgga actggtggca gcctttgacg
    19441 ttcatgcccg ggaagagttt gccgacgtgg gcgtgcagga tggaggagag gaagacgaag
    19501 ccgtgtccgc cgccacacag ttcggacggc aggggaacaa cgcgcggcag gatgcgcggt
    19561 gcctgcacaa tcgccatccc cgaaggcctg ccgaacgcgt ccgtgccgtc gagttcgacg
    19621 gcgaagttga gcgatttgtt cagcggtcgc gggaaggggt gggacgggtc gagtccgatg
    19681 ggggtcagaa tcggcagcaa ttcgcggtcg aaatagcttt cgatccactt tttctgcgcg
    19741 cccgtccagt tgcggcggcg gtaaaaatgg atgccttctt gtgccagctc gggctgaagg
    19801 acgttgttga acaggtcgta ctggtgccgt atcagggagc gcgccgcttc ggtaacgtcg
    19861 gcgatggttt cagacggcat tttgccgttg tccagcctgc gccgggggtg cagcttgttt
    19921 tcacgcttga gccacgccat gcggacttcg aaaaactcgt caagattgga cgacacgatg
    19981 cacaggaagc gcaggcgttc caaaaggggg acgtttttgt cttccgcctg tgccaacacg
    20041 cggcggttga atgccagcag gcttagttcg cggcagagga tgcggttttg ttcgggcata
    20101 aggttctccc aaagatggtt gttgttcggt cggagcgggc aggcaatgcc gtctgaaggc
    20161 ttggcggcat ctgcgccggt ttcagacggc atgacgtggc ggacagtctg tttcaggcat
    20221 cggggcaatg tgaaaacaga taccggcgcg tgcggtatcc gtctgtttca aatcacttcc
    20281 aacacaaaat aatgacgcag tttttcgtac accgcatcgc tgacgttgat gcagccgttg
    20341 gtcataatcc tgtcggacac ggacggggag gcgatgcgtt cgttccgcct ttccgacggt
    20401 atctgattcc aaacgcggtg cagggcgaaa agaaaatcac cctcctgctt gaaaccgatg
    20461 acttcgccgc cgtatccagg cttgtcggta ctgttcagcg tcagcccgaa cgtccccttg
    20521 ggcgtggcaa caccgatgag gacggggtgg cactgcctgt catcggcaaa acagagttcc
    20581 gctttggatg tgtttacgat gacttttttc ttttgaatat aagcgttgac cgcatccggt
    20641 tgcccctgtg catatacggg ggcaaccatc gataggtcgc acaatatccc taaaaacagg
    20701 cggaacggca tgtcggatta ttggcggata cgtttcggtt ttgccggcac gatttcgcgg
    20761 atgatgactt gcggctcggc tttgggtgcg ggcggcggac aggcggcatc tttcgggaag
    20821 acggggttcc agtagaagct gcgggcaaat ttgtctttat cgaaaatcac tttgtattgg
    20881 caggtagtaa catcttctac gccggacgtg ttttcagggt cgatacctac gcccggggta
    20941 tggaagtgga acaggtaatc ccattcgtgt acgccgtaca tgccttcgtc gtaatgcggg
    21001 cgacccagga ttttgtagat gtcgtctttg gtcaggccgg ggcgcatctg atccagttcg
    21061 tcataggtcg ggaatgtgcc gcgcttgttg tcgagcgtta cggaataggg tttcgggaaa
    21121 accggattgt cggtcgctcc gtcggctttg acgttgcttt tggttgcgca ggcagacaga
    21181 atgcccgccg ccaatactgc caagcccggt ttgacgattt gtttgatttt catatgcaga
    21241 atcctttttt acccgatgcc cgtctgcctt ttgttcggaa gagccgcatc aggagagttt
    21301 taaacatttg attttggttt gtaatattag cataaaaaac gtgcgtatca gtaaacgcgg
    21361 tgtatttgta cggcatacgg aatgatgcgc gtacgaattt acgcatcctg ccggcaattt
    21421 gccgattcgc cgacatcggc aacctgttat aattcctcct ttaaattcct aacgttttca
    21481 agcgaaaaac agaatgacta tgcaagaaca atatcaaccc gccgccatcg agcctgcggc
    21541 gcagaaaaaa tgggacgacg cccgtatttt caacgtctcc gaagacgctt ccaaacccaa
    21601 atactactgc ctctccatgt tcccctaccc cagcggcaag ctgcatatgg ggcatgtgcg
    21661 caactacacc atcggcgacg tattgagccg cttcaaactt ttaaacggct tcaacgtcat
    21721 gcagcctatg ggttgggacg cgttcggcat gccggcggaa aacgcggcga tgaaaaacaa
    21781 cgtcgcccct gccgcttgga cgtacgataa catcgaatac atgaaaaccc agctcaaaag
    21841 cctgggtttt gcgattgact gggcgcgcga aaccgcaacc tgcaaacccg aatactaccg
    21901 ctgggaacaa tggctgttta ccaagctgtt tgaaaaaggc atcgtttatc gcaaaaacgg
    21961 cacggtaaac tgggacccgg tcgaccaaac cgtccttgcc aacgagcaag ttatcgacgg
    22021 acgcggttgg cgttcgggcg cgttgatcga aaaacgcgaa atcccgatgt attacttcaa
    22081 aatcaccgat tacgccgaag agctgctcaa cgacttggac aagctggaac actggcctga
    22141 acaagtcaaa accatgcagc gcaactggat cggcaaatct cgcggcatga ccgtgcgctt
    22201 tgctgtttca gacgacagca aacaaggctt ggaaggcgat tacgcgaaat tcctgcaagt
    22261 ttataccacc cgccccgaca cgctgatggg tgcgacttat gttgccgttg ccgccgagca
    22321 tccgctggca gccgccgcag ccgccgacaa acccgaattg caggcattta ttgccgaatg
    22381 caaagccggt tcggttgccg aagccgatat ggcgacgatg gagaaaaaag gcgtgccgac
    22441 cggtcgctac gtcgtcaacc cgctcaacgg cgacaagctg gaagtgtgga ttgccaacta
    22501 tgtattgtgg ggctacggcg acggcgcagt gatggcggtt ccggcgcacg acgaacgcga
    22561 ttttgagttc gccgccaaat acaatctgcc taaaaaacaa gtcattgccg tcggcgacaa
    22621 cgcattcgac gcaaaccgat ggcaagaatg gtatgccgac aaagaaaacg gcgtattggt
    22681 caacagcggc gacttggacg gcttggattt tcagacggca ttcgatgccg ttgccgccaa
    22741 gctgcaaagc caaggcgcgg gcgaaccgaa aacccaatac cgcctgcgcg actggggcat
    22801 ttcgcgccaa cgctactggg gctgtccaat tcccatcgtc cattgtgaaa aatgcggcga
    22861 cgtacccgtc ccagccgacc aactgcccgt cgttctgccc gaaaacgtcg tacccgacgg
    22921 catgggttcg ccgctggcaa aaatgcccga gttttacgaa actgcctgcc cgtgctgcgg
    22981 cggcgcggcg aaacgcgaaa ccgacaccat ggacaccttc atggaatcaa gctggtattt
    23041 cttccgctat atgtcgccca agttttcaga cggcatggta tcggcagaag ccgcgaaata
    23101 ctggggcgcg gtcgaccaat acatcggcgg tatcgaacac gcgattttgc atctcttgta
    23161 cgcgcgtttc ttcaccaaac tgatgcgcga cgaaggtttg gtcaatgttg acgaaccgtt
    23221 caaacgcctg ctcacgcaag gcatggtcgt ctgcgaaacc tactaccgcg aaaacgacaa
    23281 aggcggcaaa gactggatca accccgccga tgtcgagctg acgttcgacg acaaaggccg
    23341 ccccgtttcc gccgtcctca aagccgacgg cctgcccgtc gtcatcagcg gcacggaaaa
    23401 aatgtccaag tccaaaaaca acggcgtcga tccgcaagaa ctgattaacg cctacggcgc
    23461 ggacaccgcc cgcctgttca tgatgtttgc cgcaccgccc gaacagtccc tcgaatggag
    23521 cgacagcggc gtcgaaggcg cacaccgctt cctgcgccgc ctgtggcgca ccgtttacga
    23581 atacctgaaa caaggcggcg cggtcaaagc gttcgcaggc agccaagatg gtttgtctaa
    23641 agaactcaaa gacctgcgcc acaaactgca ttccactatc gccaaagtca gcgacgacta
    23701 cggccgccgc cagcagttca acaccgccat cgccgccgtg atggaattgc tcaaccaata
    23761 cgacaaaacc gacaccggca gcgaacaagg ccgcgccgtc gcccaagaag tattggaagc
    23821 cgccgtacgt ctgctgtggc ccatcgtgcc gcacatctgc gaaaccctgt ggagcgaatt
    23881 gaacggcgcg aaattgtggg aagcaggctg gccgacagtc gacgaagcct ccttggtcaa
    23941 atccgaaatc gaagtcatgg ttcaagtcaa cggcaaactg cgcggaaaaa tcaccgtcgc
    24001 cgccgacgca tccaaagccg acctcgaagc cgccgcactc gccaccgagg gcgcagtgaa
    24061 attcatggaa ggcaagcccg ccaagaaaat catcgtcgtg ccgggcagac tggtgaacat
    24121 cgtcgtctaa ccgcttttaa ggtttagcca cacggataaa ggccgtctga aacttggaaa
    24181 cagggtttca gacggccttt ttaaggcaga tggagttgat aagtccaata acatattgga
    24241 atggaaaggt tctattggat ttagactcac tctacacacg cccccaaata taaatccatt
    24301 gtattcctca cgatgttttg gcacaattcc aagccaatca accacgcttg tactcggcat
    24361 cctaatggct tcaaaacctt ttctaaaatg ggcaggcggc aaacataaac ttgtcccctt
    24421 tatcgaacac aatctaccta ctcccacacg aaaacgcctg attgaaccct tttgcggttc
    24481 tgccgctttg tctcttgcat tggatttcga acaatatctg ctcaatgata ttaacgctga
    24541 cttaatcggc ttattccgta tcctaaaaga agaaaaatcc ggattcatcg actacgcccg
    24601 ctctttcttt atttccgaaa acaatagcga ttcaagattc tatgaattgc gggaacaatt
    24661 caacttcagc aaaaatctgc acgaacgctc ggcactattt atttatttga accgtcatgc
    24721 ttttaacggt ttatgccgtt acaacagcaa aggggtattc aatgtgccgt tcggacgcta
    24781 caaatcgccg tactttcccc aacaagaaat ggaaggtttc attcagaaat ctgacagagt
    24841 tgaattaatg tgcggagatt ttcaaatgat tctatctcag acagacaata ccgatacggt
    24901 ttattgcgat cccccttacg cgcctttaag cccaaccgct tcatttacca cttatgccaa
    24961 agaaggtttc aatttagaca atcaaatccg tcttgcccag tcagcccaac aaattgcgcc
    25021 cgattcccaa ggcgttttga tttcaaatca tgatactgaa ttcacaaggg atatttattc
    25081 ttttgctatt ctgaaaacaa ttgaagtaca acgcaatatt gccgcaaaag gcagcagccg
    25141 taaaaaagtc ggagaattat tggcaattta tgattgattt tgacaaaccg gctgaagaag
    25201 acgccattta tcaaagtcgt ttgaaaaaaa tcgtttcaga cgaccttgtc ctctacaacg
    25261 aaaattccct taacgtcatg cggaagatat tggaaaaata tccaaacggc tgttttgata
    25321 tgattttcgc agacccgcct tactttcttt ccaatgacgg cttcagttgt caaaacggac
    25381 aaatggtttc cgtcaataag ggcaactggg ataaatccaa aggaatggcg gcagatttgg
    25441 aattctacga agaatggctc cgactgtgtt acgccttatt aaaaccaaac ggcacaattt
    25501 gggtttgcgg cacattccat aatatttatt taatcggcta cctgatgcaa actatcggat
    25561 accatatttt gaacaatatt acttgggaaa aacccaatcc tccccctaat ttgtcctgcc
    25621 gtttttttac ccattcgaca gaaacaatct tatgggcaaa gaaaaataaa aaagccaaac
    25681 acacgtttca ttatgaaatg atgaaagcac aaaatgatgg caaacagatg aaatgtgttt
    25741 ggacatttcc tcctccaaac aaagccgaaa aaacattcgg caaacatccg acacaaaaac
    25801 cactcccctt gcttgaacgc tgcatactct cagcttcaaa catcggagat ttaatttttg
    25861 accctttcat gggcagcggc acaacaggcg ttgccgcctt aaaacatggt cggaaatttt
    25921 gtggttgcga actggaagaa gatttttttg aattagcaaa aaaaggttag aaaaatgatt
    25981 attggcggaa tcggtggtgc aaggacacaa acaggactca gattcgaaga acgtacagac
    26041 ttacgaaagt tgtttgaaga aattcccggg tacgacttaa gaaaaacata tgataatgcg
    26101 ggttatgaag tttggttcaa tggagaattg aaggcttatt gttttaaaaa atatgagttt
    26161 taccgatttt tgaaaagacc gggatacagt attaattgga aagaccatct gtctaaaaga
    26221 ttactacccg acaatggctt atttatcatc atccgtgata ccttatttat tattgagatc
    26281 aaattccaac aaactcccgg ttcagtagat gagaaattac aaacttgcga ttttaagaga
    26341 aaacaatata caaaattggt tcactcttta ggttggcggg ttgaatatgt ctatgttttg
    26401 aatgattggt ttacaaagcc ggaatataaa gatgttttag attatattat cagtgttaac
    26461 tgccattacc aatttaacac gattccctta aggtggtttg gactgcctga tggtgaaaca
    26521 aatgaataaa taccatattt aaaacacagc cgttcaaggt cgtctgaata tcatttcaga
    26581 cgacctttca ccaatccccg ccgttttcca tctttctgct attgtgataa agtagcccga
    26641 ccttttgttc aaaatacgcg gattccgcga cactgaatgc agcatctgtc aaagattatt
    26701 tgaaaacggt cgagttagac aagtctgccg acaatgtcga taccacatcc aaaactatcc
    26761 gcagggttta ggcggtattc cagagtacgg tgtcttatgc tgatgctgta aacaatgccc
    26821 gtatagaaaa tctaaaacgg ttgttgccga ccgttatgcc ggtttatgag caaagtgtca
    26881 gaaataaggg gcgcgttaat atagtggatt aaatttaaat caggacaagg cgacgaagcc
    26941 gcagacagta cagatagtac ggcaaggcga ggcaacgctg tactggtttt tgttaatcca
    27001 ctataaaaaa cgtcggcgtt aagggaaggg gatcgagaat ttgagccgtt gtttcaaaat
    27061 gccgtctgaa atcgtttgag attcagacgg catttaaaca gttctgcgcc cgcccgtttt
    27121 gccttcaagc ccgcgccgct taaatccaat cccccctgca acgggcgcaa aaaaatctcc
    27181 gtgcctcgcg gtcggggatg tttcgggttt cacgcccgtc tgcgccgtgc cttgctgtcg
    27241 ggctatgccg tctgcaccgc cgccgtttcg gcttggtttg atgcggtcgg gcatttatgc
    27301 ggctacgccc tgatattcag ttcggcggtc ttgcctgttt tggcaggcat attcagcagc
    27361 gcgtctattg tgaacttgct gattttgccg tttgccaagt cggctacgca atggcttcga
    27421 tacccttgtt tttgacgatg gtcagcagct tcaacgccgc gccgctgggc tttttaacgc
    27481 cccgctccca agccgaaacg tgattttttc ccacgttgag atagatggcg aaagcggctt
    27541 gcgatagtgc ctccttctcc ctgattgcct tgatgtctcc gccgctcaac ggtttgattt
    27601 cggtcaggca ggacttgtca aagccgcgca tagtcttttt gtcgattgcg ccgatgttgt
    27661 aagccccttc catcatttca tgaatggcgg ctaatgcctc gcttttgtat ttcatgattc
    27721 tatctccgtg ataatgccgt cttctttcaa agccgccagc tctgcccgcg tgtatttcag
    27781 ataatatgcg gcggcttttc ggtaaacgtc cagttcttta tccgaaatgt tttccctgtc
    27841 gttcttggca aaggcgtaaa cgaaaatgcc ctatctgcct gtttgaacaa tatcaggctg
    27901 cgatagccgc cgcttctgcc ttgtccttgc cttgctatgc gctgcttaat cacaccgccg
    27961 cctaaatctg cgtctatcag cccgttatcc gcccgctcta ccgcttccag cagctcggaa
    28021 tcgttgattt tgtgcttctt ggcaaatttc actatccatt ggtttttgaa tatccgcatt
    28081 gtgtagccgt tgattagtga tacttggaat tataccagag acagacaaca cggcaagctg
    28141 ccttttttat gccccgcaat ttctccgttt atgccgcctg aaacactggc ggctaacctg
    28201 attatttttt aatcaatcgc ttttaatggc tcaaattgcg tttttagcgc gtttcgctgt
    28261 cttcctatgt ccccatatat aaccaagtgg tttaaccgcc attcctgctc aaaataggcg
    28321 cggttccgtg cgttttggct tttcattccg ctacgctccc actgccaaga cggtgaaaaa
    28381 ccggaaaacc ccaaaagttg ttaccgattc gttaccattt gttaccgcat ttgttaccaa
    28441 ttttttatct ttttcttatt ttatagtgaa ttaaatttaa accggtacgg caaggcgagg
    28501 caacgccgta ccggtttaaa tttaatccac tatagtatag gttttttcca aaaacccaaa
    28561 aaaaaaccgc tctgcatctt ggacggtttc cccctcattc cctacggtgc gtcagtattc
    28621 cccgcaagct atttcccgct tggcattcct gatttggtgg tcgttcagct ttatttttac
    28681 ggtattttct cgcggtattt tcggatgctg taaaaaatca ggttagttca attagggtgg
    28741 attggacggg attgtacggt caggaagggg gacggcagga taacaatcag cctgaaagcc
    28801 ttgtattgat tgggattggt tgacggcatt agacaggatt aaacgaaaaa aaacgcttag
    28861 aatttctaag cgttttgtgt gttggtgccg acagcgagat ttgaactcgc acagcctacg
    28921 gccactaccc cctcaagata gcgtgtctac caatttcacc atgtcggcat ttgaaaaact
    28981 gttatttctg ctgctgagga acaggggcag aaggttcggt attgcttacg ggtttgggtg
    29041 cttgctgagt ttgttgtacg ttgctgaagt ccaaaccgtg ttttgttgtg tgggtgtgaa
    29101 tatacaccat agccatgcag gttgcaaaga aaaatgttgc tgcaacggcg gtcgagcggc
    29161 tgaggaagtt agcgttgccg gcagagccga atacgccttg cgcgctgccg cttcccgatc
    29221 cgaaagtcgc gccggcatcc gcgcctttgc cgtgttggag caatactaac acgatgacgg
    29281 ccaaagcgga aattatatta acaatccaaa ttagggtttt gaaggcttcc atatttttct
    29341 acgcattttg tgcggcactg atgatggcgg taaaggagtc gtacgacaat gacgcgccgc
    29401 cgacgagtgc gccgtccaca taaggtactg cgaagatgtc ggccgcgttg tccgctttca
    29461 cacttccgcc gtaaaggacg cggattttaa catcgcttcc gcacaaagac aagatttctt
    29521 tgtagatgaa tgcgtgcata tcggcaatct gttcgacggt ggcgactttg ccggtgccga
    29581 tcgcccagac gggttcgtag gcgacggcga tgtttttggt atccagccct tgcaggatgg
    29641 aaagctgatg ggcgatgact tcgtgttctt tgccggcttc gcgctcttcg aggctttcgc
    29701 cgacgcacaa taacgggatg agtccgacgt tgaggacgtt ttccattttg cggcgttgga
    29761 tttcgttttt ttcgccgaaa taaaggctgc gttcggagtg tccgatgagg acgatgtctg
    29821 tgccggtgtc ggcgagcatt tcggcggaca cttcgccggt gtacgcgccg ttgtcgggga
    29881 agcggctcac gtcttgggcg caggtgagga tgcggttgtt taagacgatt tgcatggcgt
    29941 tgtgcagttg cagcaggtaa acggtcgggg cggcgagtcc gatgaggacg cgttcggcgg
    30001 tggggaggat gcggaagcgg tgcatgagcg aattgttgtt ctggagccgg ccgttcattt
    30061 tccagttgcc gatgacccat ttttgatccc acattccgat ttggtgatac atcttttttg
    30121 ctccgtgtcg tgttttttct gtctgccgcg tgtggcgcgt tgcaatgtga agtttagtgg
    30181 atatgcggcg ggttcgcaac ttggggcggg cggctgcggg ggcggtttgg aatgttgttt
    30241 cgggcaggtt gttttataat ggccgcctga tatgtatgca actataggag atgtgatgca
    30301 cgcgcttcat ttttcggctt cggacaaggc cgcgctttat cgggaggtgt tgccgcagat
    30361 tgagtctgtg gtggcggacg agacggattg ggtggcgaat ttggcgaaca cggcggcggt
    30421 tttgaaggag gcgttcggtt ggttttgggt gggtttttat ttggtcgata cgcgttcgga
    30481 cgaattggtt ttggcaccgt ttcaggggcc tttggcgtgt acgcggattc cgttcggtcg
    30541 cggggtgtgc ggtcaggctt gggcgaaggg cgggacggtg gtcgtcgggg atgtggacgc
    30601 gcatcccgac catattgcct gttcgtcttt gtcgcgttcg gagattgtcg tgccgctgtt
    30661 ttcagacggc cgctgtatcg gcgtgttgga cgcggacagc gaacatttgg cgcagtttga
    30721 tgagacagat gctttgtatt tgggcgaact ggcgaagatt ttggagaagc ggtttgaggc
    30781 ttcgcgccag gcggcttgag tgatggaaag gggcgggcgg cgcgtgccga agttggcgcg
    30841 gcgggagtgt ggttttataa tgcctgccat tgttgaaaca attatttgac ggagcactaa
    30901 atggattttg aaaaagcgcg gttcaatatg gtcgaacagc aaatccgtcc ttgggatgta
    30961 ttggattttg acgttttgga cgctttggag gagattccgc gcgagctttt tgtcgatgag
    31021 gatttgcagg gtttggcgta tgcggatatg gcgctgccgc ttgccaacgg tcataagatg
    31081 ctggagccga aagtcgtggc gcggctggcg cagggcttga agctgacgaa aaacgatacg
    31141 gttttggaaa tcggcacggg ttcgggctat gcgaccgcgc ttttggcaaa attggctggt
    31201 cgtgtggtgt cggacgacat cgatgccgaa cagcaaaacc gcgccaaagc ggtgttggac
    31261 ggcttgtctt tggaaaacat tgattatgtg caaaacaacg ggttgaccga actttccgca
    31321 ggtgcgccgt ttgatgcggt ttatgtcggc ggtgcggtaa accttgtgcc tgaagtgttg
    31381 aaagaacagt tgaaagatgg cggacgcatg gtggttatcg taggacgcaa gcctgttcaa
    31441 cgcgcgcttt tgattacgcg caggggcgat gtgtttgaag agaaggtgct gttcgatacc
    31501 ttggtggcgc atttggatga taaggatgcc gatccgtttg gtggttttca gttttgatgt
    31561 tcggattgcg atgccgtctg aaagcgggtt tggggcttca gacggcattt tgcttggttt
    31621 tttttggggg gtgcgatgga tattgtgcaa cttgggtcgg cggaattgaa ggcgtggatg
    31681 gacgaagggc ggatgttttg tttgttggac gtgcgtacgg atgaagaaac ggcggtttgt
    31741 tcgctgccaa atgcgctgca tatcccgatg aatctgattc cgctgcggca gaacgagctg
    31801 ccggatgatg tgccgcttgt ggtgtattgc caccacggta tccgcagcct gcatacggcg
    31861 atgtatctgg cggacgcggg ttttgaaaac ctgtacaacc ttcagggcgg catcgatgca
    31921 tgggcggccg agattgacgg caacatgatg cgttattgag gcag
//
LOCUS       DAXISH010000015        31860 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.015, whole genome shotgun sequence.
ACCESSION   DAXISH010000015 DAXISH010000000
VERSION     DAXISH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 31860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31860
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.015"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..522
                     /locus_tag="ACFOV4_000733"
     CDS             <1..522
                     /locus_tag="ACFOV4_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC7618795.1"
                     /translation="QAIEVDEEGQINGQTTPSKDKDARWIKKNGLYKLGYKQHTRTDA
                     EGYIEKLHITPANAHECKHLSPLLEGLPKGTTVYVDKGYDSAENRQHLEEHQLQDGIM
                     RKACRNRPLTEAQTKRNRYVVEQSFGTLHRKFRYARAAYFGLIKVSAQSHLKAMCLNL
                     LKAANRLSAPAAA"
     gene            661..777
                     /locus_tag="ACFOV4_000734"
                     /pseudo
     CDS             661..777
                     /locus_tag="ACFOV4_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            788..1758
                     /locus_tag="ACFOV4_000735"
                     /pseudo
     CDS             788..1758
                     /locus_tag="ACFOV4_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225028.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter six-transmembrane
                     domain-containing protein"
     gene            complement(1809..2861)
                     /gene="sohB"
                     /locus_tag="ACFOV4_000736"
     CDS             complement(1809..2861)
                     /gene="sohB"
                     /locus_tag="ACFOV4_000736"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HFC7618796.1"
                     /translation="MWKEILLNYGIFLLELLTVFGAIALIVLAIVQSKKQSESGSVVL
                     TDFSENYKKQRQSFEAFFLSGEEAKHQEKEEKKKEKAEAKAEKKRLKEGGEKSAETQK
                     SRLFVLDFDGDLYAHAVESLRHEITAVLLIAKPEDEVLLRLESPGGVVHGYGLAASQL
                     RRLRERNIPLTVAVDKVAASGGYMMACVADKIVSAPFAIVGSVGVVAEVPNIHRLLKK
                     HDIDVDVMTAGEFKRTVTFMGENTEKGKQKFRQELEETHQLFKQFVSENRPQLDIEEV
                     ATGEHWFGRQALALNLIDEISTSDDLLLKAFENKQVIEVKYQEKQSLIQRIGLQAEAS
                     VEKLFAKLVNRRADVM"
     gene            complement(2965..3054)
                     /locus_tag="ACFOV4_000737"
     tRNA            complement(2965..3054)
                     /locus_tag="ACFOV4_000737"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3018..3020),aa:Leu,seq:taa)
     gene            complement(3157..3230)
                     /locus_tag="ACFOV4_000738"
     tRNA            complement(3157..3230)
                     /locus_tag="ACFOV4_000738"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3196..3198),aa:Cys,seq:gca)
     gene            complement(3256..3331)
                     /locus_tag="ACFOV4_000739"
     tRNA            complement(3256..3331)
                     /locus_tag="ACFOV4_000739"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3296..3298),aa:Gly,seq:gcc)
     gene            complement(3353..3428)
                     /locus_tag="ACFOV4_000740"
     tRNA            complement(3353..3428)
                     /locus_tag="ACFOV4_000740"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3393..3395),aa:Gly,seq:gcc)
     gene            complement(3452..3527)
                     /locus_tag="ACFOV4_000741"
     tRNA            complement(3452..3527)
                     /locus_tag="ACFOV4_000741"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3492..3494),aa:Gly,seq:gcc)
     gene            complement(3553..3628)
                     /locus_tag="ACFOV4_000742"
     tRNA            complement(3553..3628)
                     /locus_tag="ACFOV4_000742"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3593..3595),aa:Gly,seq:gcc)
     gene            complement(3708..4271)
                     /gene="pgsA"
                     /locus_tag="ACFOV4_000743"
     CDS             complement(3708..4271)
                     /gene="pgsA"
                     /locus_tag="ACFOV4_000743"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFC7618797.1"
                     /translation="MPWNLPIFLTWLRVLLIPVMTALFYLPFPWFAEETINLTAAVIF
                     AVAALTDWFDGFLARLWKQTSDFGAFLDPVADKLMVAVSLLLLVKLDRTYVLFAMIII
                     GREITISALREWMAQMGKRNSVAVATVGKFKTAAQMLAIFLLLLNIPDFYGFNLVVIG
                     NVLMFIASLLTVWSMLYYLKMAWKEIA"
     gene            complement(4377..4800)
                     /locus_tag="ACFOV4_000744"
                     /pseudo
     CDS             complement(4377..4800)
                     /locus_tag="ACFOV4_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4934..4999)
                     /locus_tag="ACFOV4_000745"
                     /pseudo
     CDS             complement(4934..4999)
                     /locus_tag="ACFOV4_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5132..5467)
                     /locus_tag="ACFOV4_000746"
     CDS             complement(5132..5467)
                     /locus_tag="ACFOV4_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003699221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFC7618798.1"
                     /translation="MFKDWKEHTALVKKSFGELGKAHPKMLQAYGALEQAAAAEALDA
                     KTRELIAIAVAITTRCESCISVHAAAAAKAGATDSEIAGALATAIALNAGAAYTYALR
                     ALEAVETQK"
     gene            5596..6501
                     /gene="mtrA"
                     /locus_tag="ACFOV4_000747"
     CDS             5596..6501
                     /gene="mtrA"
                     /locus_tag="ACFOV4_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter MtrCDE transcriptional
                     activator MtrA"
                     /protein_id="HFC7618799.1"
                     /translation="MDILDKLVDFAQLTGSVDVQCLLGGQWSVRHETLQREGLVHIVT
                     SGSGYLCIDGETSPRPVSTGDIVFFPRGLGHVLSHDGKCGESLQPDMRQHGAFTVKQC
                     GNGQDMSLFCARFRYDTHADLMNGLPETVFLNIAHPSLQYVVSMLQLESKKPLTGTVS
                     VVNALSSVLLVLILRAYLEQDKDVELSGVLKGWQDKRLGHLIQKVIDKPEDEWNVDKM
                     VAAANMSRAQLMRRFKSRVGLSPHAFVNHIRLQKGALLLKKNPDSVLSVALSVGFQSE
                     THFGKAFKRQYHVSPGQYRKEGGQK"
     gene            complement(6563..7051)
                     /locus_tag="ACFOV4_000748"
     CDS             complement(6563..7051)
                     /locus_tag="ACFOV4_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFC7618800.1"
                     /translation="MKKYLIPLSIVAVLSGCQSIYVPTLTEIPVNPINTVKTEAPAKG
                     FRLASSHWTDVAKISDEATRLGYQVGIGKMTKVQAAQYLNNFRKRLVGRNAVDDSMYE
                     IYLRSAIDSQRGAINTEQSKLYIQNALRGWQQRWKNMDVKPNNPAFTNFLMEVMKMQP
                     LK"
     gene            7198..8100
                     /locus_tag="ACFOV4_000749"
     CDS             7198..8100
                     /locus_tag="ACFOV4_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFC7618801.1"
                     /translation="MDTAKKDILGSGWMLVAAACFTIMNVLIKEASAKFALGSGELVF
                     WRMLFSTVALGAAAVLRRDTFRTPHWKNHLNRSMVGTGAMLLLFYAVTHLPLATGVTL
                     SYTSSIFLAVFSFLILKERISVYTQAVLLLGFAGVVLLLNPSFRSGQETAALAGLAGG
                     AMSGWAYLKVRELSLAGEPGWRVVFYLSVTGVAMSSVWATLTGWHTLSFPSAVYLSCI
                     GVSALIAQLSMTRAYKVGDKFTVASLSYMTVVFSALSAAFFLAEELFWQEILGMCIII
                     LSGILSSIRPTAFKQRLQSLFRQR"
     gene            complement(8141..9271)
                     /locus_tag="ACFOV4_000750"
     CDS             complement(8141..9271)
                     /locus_tag="ACFOV4_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7618802.1"
                     /translation="MTKHLPLAVLTALLLAACGGSDKPPAEKPAPAENRNVLKIYNWS
                     EYVDPETVADFEKKNGIKVTYDVYDSDETLESKVLTGKSGYDIVAPSNAFVGRQIKAG
                     AYQKIDKSLIPNYKHLNPEMMRLMDGVDPGHEYAVPFYWGTNTFAINTERVKKALGTD
                     KLPDNQWDLVFDPEYTSKLKQCGISYLDSAAEIYPMVLNYLGKNPNSSNTEDIREATA
                     LLKKNRPNIKRFTSSGFIDDLARGDTCVTIGFGGDLNIAKRRAEEAGGKEKIRVMMPK
                     EGVGIWVDSFVIPKDAKNVANAHKYINDFLDPEVSAKNGNFVTYAPSSKPARELMEDE
                     FKNDNTIFPTEEDLKNSFIMVPIQPAALKFMVRQWQDVKAGK"
     gene            9476..12100
                     /gene="alaS"
                     /locus_tag="ACFOV4_000751"
     CDS             9476..12100
                     /gene="alaS"
                     /locus_tag="ACFOV4_000751"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFC7618803.1"
                     /translation="MKTSELRQKFLKFFETKGHTVVRSSSLVPHDDPTLLFTNAGMNQ
                     FKDVFLGFDKRPYSRATTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGDYFK
                     RDAIHFAWEFLTSPEWLNIPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKG
                     AKYVSDNFWQMGDTGPCGPCSEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFN
                     RDEQGNMNPLPKPSVDTGMGLERMAAVMQHVHSNYEIDLFQDLLKAVARETGAAFSMD
                     EPSLKVIADHIRSCSFLIADGVLPSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLV
                     ADLVKEMGDAYPELKEKQVQIEEALKNEESRFAQTLETGMALLENALAKGGKTLDGEI
                     IFKLYDTYGFPYDLTADICRERNIELDEAGFEREMEAQRARARAAQSFKANAQLPYDG
                     QDTEFKGYSERQTESKVLALYKDGEQVDELNEGDSGAVVIDFTPFYAESGGQVGDVGY
                     IFSGENRFEVRDTQKIKAAVFGQFGVQTSGRLKVGDSVTAKVDDEIRNANMRNHSATH
                     LMHKALRDVLGEHVEQKGSLVTAESTRFDISHPQAVTAEEIAEVERRVNEAILANVAV
                     NAAIMSMEDAQKTGAMMLFGEKYGDEVRVLQMGGFSTELCGGTHVSRTGDIGLFKIIS
                     EGGIAAGVRRIEAITGLNALKWAQEQERLVKDIIAETKAQTEKDVLAKIQAGAAHAKA
                     LEKELAKAKAELAVHAGAKLLDDAKDLGAAKLVAAQIEADAAALREIVTDLTGKSDNA
                     VILLAAVNDGKVSLCAGVSKPLTGKVKAGDLVKFAAEQVGGKGGGRPDLAQAGGTDAG
                     KLPEMLVSVESWLCQKLS"
     gene            12162..12893
                     /locus_tag="ACFOV4_000752"
     CDS             12162..12893
                     /locus_tag="ACFOV4_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618804.1"
                     /translation="MNTKTELQKLLEEDISTLTETLICADALPPRYVRSIATPIVRRW
                     LIDKQLNILAKEIGLTIELPILDTSLVFEKLSTLENKVNFYMAGGVYLGGEFISSIYH
                     SSQEFSGEPIIYAEPNIILCPAEKFLTLKRVFHNGNIFNMNQIITFLSNKQGGVHFDK
                     NYDKYKTWQVAIEKAANFLKLGNPYNEDKLSLSEEHDTILVVLPLEKGYEWNCLEIEV
                     LSAAQSLANIYCNKVRLIDGHVWKE"
     gene            13200..14093
                     /locus_tag="ACFOV4_000753"
     CDS             13200..14093
                     /locus_tag="ACFOV4_000753"
                     /inference="COORDINATES: protein motif:HMM:NF042870.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IIL restriction-modification enzyme MmeI"
                     /protein_id="HFC7618805.1"
                     /translation="MKTLLQLQTAAQNFAAYYKDQTDERREKDTFWNEFFAIFGIDRK
                     NVAHFEYPVKDPADNTQFVDIFWEGIFLAEHKSANKNLTKAKEQAERYLQEIGRTKPS
                     ALPEYYAVSDFAHFHLYRRVPEEGVENQWQFPLEALPEYITRGVFDFMFGIEAKVRQI
                     QEEADIQAAAAIGRLHDALKEEGIYEEHELRLFITRLLFLFFADDSAVFQRNYLFQDF
                     LESCKETDTLGDKLNQLFEFLNTPDQKRSKTQSEKFKGFEYVNGGLFKERLRTFDFTA
                     KQHRALIDCGNFDWRNMRPLQ"
     gene            14259..16199
                     /locus_tag="ACFOV4_000754"
                     /pseudo
     CDS             14259..16199
                     /locus_tag="ACFOV4_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
     gene            complement(17100..17783)
                     /locus_tag="ACFOV4_000755"
     CDS             complement(17100..17783)
                     /locus_tag="ACFOV4_000755"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFC7618806.1"
                     /translation="MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKE
                     NGYEFDIAFTSVLTRAIKTCNIVLEESDQLFVPQIKTWRLNERHYGRLQGLDKKQTAE
                     QYGDEQVRIWRRSYDTLPPLLDKDDEFSAHKDRRYAHLPADVIPDGENLQVTLERVLP
                     FWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDN
                     LKVIEKFYL"
     gene            18079..20382
                     /gene="parC"
                     /locus_tag="ACFOV4_000756"
     CDS             18079..20382
                     /gene="parC"
                     /locus_tag="ACFOV4_000756"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009340 - DNA topoisomerase IV complex
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFC7618807.1"
                     /translation="MNMQPHAPHTDSNTLMLGQYAERAYLEYAMSVVKGRALPEVSDG
                     QKPVQRRILFAMRDMGLTAGAKPVKSARVVGEILGKYHPHGDSSAYEAMVRMAQDFTL
                     RYPLIDGIGNFGSRDGDGAAAMRYTEARLTPIAELLLSEINQGTVDFVPNYDGAFDEP
                     LHLPARLPIVLLNGASGIAVGMATEIPSHNLNEVTQAAIALLKKPTLETADLMQYIPA
                     PDFAGGGQIITPADELRRIYETGKGSVRVRARYEIEKLARGQWRVIVTELPPNANSAK
                     ILAEIEEQTNPKPKAGKKQLNQDQLNTKKLMLDLIDRVRDESDGEHPVRLVFEPKSSR
                     IDTDTFINTLMAQTSLEGNVSMNLVMMGLDNRPAQKNLKTILQEWLDFRTVTVTRRLK
                     FRLNQVEKRLHILEGRLKVFLHIDEVIKVIRESDDPKADLMAAFGLTEIQAEDILEIR
                     LRQLARLEGFKLEKELNELREEQGRLNILLGDENEKRKLIIKEMQADMKQYGDARRTL
                     VEEAGRAVLTQTTADEPITLILSEKGWIRSRAGHNLDLSQTAFKEGDRLKQTLEGRTV
                     LPVVILDSLGRTYTLDAAEIPGGRGDGVPVSSLIELQNGAKPVAMLTGLPEQHYLLSS
                     SGGYGFIAKLADMVGRVKAGKVVMTTDSGETVLPPIAVYASSFINPDCKIIAATSQNR
                     ALAFPIGELKIMAKGKGLQIIGLNAGESLTHTAVSSEPEILIESEGRRGAAHKDRIPV
                     SLLEAKRGKKGKLLPISGSLKQLSSPK"
     gene            20403..21979
                     /locus_tag="ACFOV4_000757"
                     /pseudo
     CDS             20403..21979
                     /locus_tag="ACFOV4_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237220.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
     gene            21972..22439
                     /locus_tag="ACFOV4_000758"
     CDS             21972..22439
                     /locus_tag="ACFOV4_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009117578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFC7618808.1"
                     /translation="MTELQHPVLVVDDETDILDLMEMTLMKMGLRVHTASGVAEAKNK
                     LDSQRYSLVLTDMRMPDGSGLEVVQHINSRLLDTPVAVITAFGNADQAQEALRCGAFD
                     PDTMQIQDYLDQIERDIIEQTLKQTEGNRTQAAKRLGISFRSMRYRMERLNIG"
     gene            22543..23295
                     /locus_tag="ACFOV4_000759"
     CDS             22543..23295
                     /locus_tag="ACFOV4_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC7618809.1"
                     /translation="MTDILIDNTATETVRTLIRAFPLVPVSQPPEQGSYLLAEHDTVS
                     LRLVGEKSSVIVDFASGAAQYRRTKGGGELIAKAVNHTAHPTVWDATAGLGRDSFVLA
                     SLGLAVTAFEQHPAVACLLSDGIRRALLNPETQDTAARINLHFGNAAVQMPALVQTQG
                     KPDIVYLDPMYPERRKSAAVKKEMTYFHRLVGEAQDEAALLHTARQTAKKRVVVKRPR
                     LGEHLAGQAPAYQYTGKSTRFDVYLPYGTDKG"
     gene            24217..24329
                     /locus_tag="ACFOV4_000760"
                     /pseudo
     CDS             24217..24329
                     /locus_tag="ACFOV4_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(24428..24634)
                     /locus_tag="ACFOV4_000761"
     CDS             complement(24428..24634)
                     /locus_tag="ACFOV4_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2788 domain-containing protein"
                     /protein_id="HFC7618810.1"
                     /translation="MDEAVFADWALKICLTGLIIFLGFIVWNLGKESKAGKFGIAILF
                     LVLGLGVFGFVFKELLIKFLVLPK"
     gene            complement(24729..25898)
                     /gene="metZ"
                     /locus_tag="ACFOV4_000762"
     CDS             complement(24729..25898)
                     /gene="metZ"
                     /locus_tag="ACFOV4_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-succinylhomoserine sulfhydrylase"
                     /protein_id="HFC7618811.1"
                     /translation="MSKKLHPQTLAIRGGKEQTGYREHNQALFLTSSFMWDNAQHAAD
                     LFSKKIKGFTYTRTANPTTAAFEKRIAALEGAERAVATSTGMSAIQAAFFTFLQAGDH
                     VISSRSLFGTTVGFINNIVTKFGIEVSHVSPTDINEWKAAVKANTKLLFLETPSNPLG
                     EVADLEALAELAHGIGALLVVDNSLLSPVGSQPLKHGADISVSSATKAIDGHGRVMGG
                     VLAGSEELMAQVAVYCNSCGLAMSPFNAWQLLSGVETLSLRMEKQFDNALKIAQWLQA
                     QPQVQAVYYTGLPDHPQAELIRKQQNGGGIVIGFEVADQAAAWKVVDGVELFSRTANL
                     GDVRSTITHPWTTTHGRMQPEEKLAANIRPGLVRLSVGLEYVGDLIDDLKQALAR"
     gene            complement(26197..26958)
                     /locus_tag="ACFOV4_000763"
     CDS             complement(26197..26958)
                     /locus_tag="ACFOV4_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618812.1"
                     /translation="MDVNKEPNWEKRLENLRQTRRMKAVPTYAPLSRPSETGTDAPVP
                     KLDDESRDHVLKAYLKKWQEEHNAAVADCGEEVETDPMIVLQENWLNAQASLQMSVSE
                     KHIESRRRILFDAKKDSAEFETGQIEGGENADAAESGTAADGVAENGEGGAEEALMPV
                     QINILNPKAVNRREVFCLSEQELTERLIKRLRPHLTDTVNGIIRTAVQKQMALFTYQL
                     QQMLHDQAGAVVEDVLEHDVRKILNDIKYELKYKR"
     gene            27058..27309
                     /locus_tag="ACFOV4_000764"
     CDS             27058..27309
                     /locus_tag="ACFOV4_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618813.1"
                     /translation="MGSIEQRLEYLEEANDVLRMQNHVLSTAFKALIRALPAETAEIA
                     VESIQLAFEDALAELSYEDSPHTDLFHDVTYAFFREKER"
     gene            27361..28167
                     /locus_tag="ACFOV4_000765"
     CDS             27361..28167
                     /locus_tag="ACFOV4_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="HFC7618814.1"
                     /translation="MNMKKWIAAALACSALALSACGGQGKDAAAPAANPDKVYRVASN
                     AEFAPFESLDSKGNVEGFDVDLMNAMAKAGNFKIEFKHQPWDSLFPALNNGDADVVMS
                     GVTITDDRKQSMDFSDPYFEITQVVLVPKGKKISSSEDLKNMNKVGVVTGYTGDFSVS
                     KLLGNDNPKIARFENVPLIIKELENGGLDSVVSDSAVIANYVKNNPTKGMDFVTLPDF
                     TTEHYGIAVRKGDEATVKMLNDALKKVRESGEYDKIYAKYFAKEDGQAAK"
     gene            28474..29997
                     /locus_tag="ACFOV4_000766"
     CDS             28474..29997
                     /locus_tag="ACFOV4_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HFC7618815.1"
                     /translation="MTVIKQEDFIQSICDAFQFISYYHPKDYIDALYKAWQKEENPAA
                     KDAMTQILVNSRMCAENNRPICQDTGIATVFLKVGMDVQWDADMSVEEMVNEGVRRAY
                     TWEGNTLRASVLADPAGKRQNTKDNTPAVIHMSIVPGDKVEVTCAAKGGGSENKSKLA
                     MLNPSDNIVDWVLKTIPTMGAGWCPPGILGIGIGGTPEKAVLMAKESLMSHIDIQELQ
                     EKAASGAELSTTEALRLELFEKVNALGIGAQGLGGLTTVLDVKILDYPTHAASKPIAM
                     IPNCAATRHVEFELDGSGPVELTPPRVEDWPDLTYSPDNGKRVDVDKLTKEEVASWKT
                     GDVLLLNGKILTGRDAAHKRLVDMLNKGEELPVDFTNRLIYYVGPVDPVGDEVVGPAG
                     PTTATRMDKFTRQMLEQTDLLGMIGKSERGVATCEAIADNKAVYLMAVGGAAYLVAKA
                     IKSSKVLAFPELGMEAIYEFEVKDMPVTVAVDSKGESIHATAPPQWQAKIGIIPVES"
     gene            30095..31507
                     /gene="trkA"
                     /locus_tag="ACFOV4_000767"
     CDS             30095..31507
                     /gene="trkA"
                     /locus_tag="ACFOV4_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HFC7618816.1"
                     /translation="MKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRL
                     DVQTVFGNGASPFTLERAGAEDADLLLALSRSDETNIVACKVAADLFNIPGRIARVRS
                     SEYLEYLSPKLENNENGSLSIFGITETISPEQLVTEQLAGLIDCPGALQVLRFADDRV
                     RMVIIQARRGGLLVGRSIADIAQDLPDGADCQICAVYRNNRLIVPAPQTVIIEGDEIL
                     FAAAAENIGAVIPELRPKETSTRRIMIAGGGNIGYRLAKQLEHAYNVKIIECRSRRAE
                     WIAENLDNTLVLQGSATDETLLDNEYIDEIDVFCALTNDDESNIMSALLAKNLGAKRV
                     IGIVNRSSYVDLLEGNKIDIVVSPHLITIGSILAHIRRGDIVAVHPIRRGTAEAIEVV
                     AHGDKKTSAIIGRRISGIKWPEGCHIAAVVRAETGETIMGHHTETVIQDGDHIIFFVS
                     RRRILNELEKLIQVKMGFFG"
BASE COUNT         8014 a         8926 c         7734 g         7186 t
ORIGIN      
        1 caggccatag aagttgacga agaaggacaa atcaacggtc aaaccacacc gagtaaggac
       61 aaagatgccc gttggataaa gaaaaacggc ctctacaaac tcggttacaa acaacatacc
      121 cgtaccgatg cggaaggcta tatcgagaaa ctgcacatta ctcccgccaa tgcccatgag
      181 tgcaaacacc tgtcgccttt gctggaagga ctgcccaaag gtacgaccgt ctatgtcgac
      241 aaaggctacg acagtgcgga aaaccggcaa catctggaag aacatcagtt gcaggacggc
      301 attatgcgca aagcctgccg caaccgtccg ctgacggagg cacaaaccaa acgcaaccgt
      361 tatgtggtcg aacaaagctt cggtacgctg caccgtaaat tccgctatgc gcgggcagcc
      421 tatttcgggc tgattaaagt gagtgcgcaa agccacctga aggcgatgtg tttgaacctg
      481 ttgaaagcgg ccaacaggtt aagtgcgccc gctgccgcct aaaaggcagc ccggatgcct
      541 aattatcggg cgtccggtga ggattaaggg ggtatttggg tagaattagg agtaattagg
      601 agcgaaaata gacgaaaacc tgtgtttggg tttcggctgt cgggagggaa aggaattttg
      661 caaaggtctc acaaagtatt tgccacattc ggcgacaagc gcacaacccg gctgtttgcc
      721 gatttggatg cactggctga agtgatggaa aaaacaatct cggaaaataa aaaatagggg
      781 ggcaaatatg tggaaaatgt tgaaacacat agcccaaacc caccgcaagc gattgattgg
      841 cacattttcc ctggtcggac tggaaaacct tttgatgctg gtgtatccgg tgtttggcgg
      901 ccgggcgatc aatgccgtga ttgcggggga ggtgtggcag gcgttgctgt acgctttggt
      961 tgtgctttta atgtggctgg tcggtgcggc gcggcggatt gccgatacac gcacgtttac
     1021 gcggatttat accgaaatcg ccgtgccggt tgtgttggaa cagcggcagc ggtaagtccc
     1081 gcattcggca atatagtgga ttaaatttaa accagtacgg cgttgtctcg ccttgccgta
     1141 ctatttgtac tgtctgcggc ttcgtcgcct tgtcctgatt tttgttaatc cactataact
     1201 gcgcgggttg ccctgtcgcg tgagtttgtc agcttttttg aagaacacct gccgattgcc
     1261 gcgacatccg tcgtatccat attcggcgcg tgcatcatgc tgctggtgct ggaattttgg
     1321 gtcggcgtgt cggcggtggg catacttgcg ttgtttttat ggcttttgcc acgttttgcg
     1381 gccatcagcg aaaacctgta tttccgcctg aagaacagct tggaacgcga caaccacttt
     1441 atccgaaaag gcgaccggcg gcagctgtac cgccattacg gactgcttgc gcgcctgcgt
     1501 gtgctgattt ccaaccgcga agccttcggc tatctctgcg tcggcacggc gatgggtatt
     1561 ttgttcggct ttgcttttgt gatgatgacg ctcaaaggct acagcagcgc ggggcatgtc
     1621 tattcggtcg gcacttatct gtggatgttt gccatgagtt tggacgacgt gccgcgattg
     1681 gtcgaacaat attccaattt gaaagacatc ggacaacgga tagagtggtc ggaacggaac
     1741 atcaaagccg gaacttgaaa aatgccgtct gaacacgctt cagacggcat ttccatccgt
     1801 tcggcaaact acatcacatc cgcccgccgg ttgacaagtt tggcaaacaa cttttcaaca
     1861 gaagcttccg cctgcaaacc aatgcgctgg atcaggcttt gcttctcctg atatttcact
     1921 tcgataacct gtttgttttc aaacgctttc aacaacaaat catcactggt cgaaatctcg
     1981 tcaatcaagt tcaacgccaa cgcctgccga ccgaaccaat gctcgcccgt tgccacttcc
     2041 tcaatatcca attgagggcg gttctcgctg acaaactgct tgaacaactg atgcgtttcc
     2101 tccagttcct gtcggaattt ctgtttgccc ttttccgtat tttcacccat aaaagtaacc
     2161 gtgcgcttaa attcgcccgc cgtcatcaca tccacatcaa tatcatgttt tttcaacagg
     2221 cggtggatat tcggtacttc cgccaccaca cccaccgaac cgacaatcgc aaacggagcg
     2281 gaaacaattt tatccgccac acacgccatc atataaccgc cgctcgccgc caccttatcg
     2341 acggcgacgg tcagcggaat attgcgttcg cgcaaacgcc taagctgtga agccgccaaa
     2401 ccgtaaccgt gaaccacgcc gcccggactt tccaatctaa gcagaacctc atcttcaggc
     2461 ttggcaatca aaagcaccgc cgtaatctca tgacgcaagg attctacggc gtgtgcatac
     2521 aaatcgccgt caaaatccaa cacaaaaagg cgggattttt gcgtttcggc agatttctcc
     2581 ccaccctcct tcaaacgctt tttctctgct ttggcttccg ccttttcctt tttcttttcc
     2641 tctttttcct gatgttttgc ctcttccccg cttaaaaaga atgcttcaaa cgattgccgc
     2701 tgttttttat aattttccga aaaatccgtc agtacgacac tgccgctttc cgactgtttc
     2761 ttactctgta cgatagccaa cacaatcagc gcaattgcac cgaacacggt aagcagttcg
     2821 agcaggaaaa taccgtaatt cagtaaaatt tctttccaca ttgattggat ttcctcttgt
     2881 tcaggcatga acatgtcaat attgtccatc accgtccgac agataaaaaa ataaccgctt
     2941 ggagcggcat tgtcattttc agcttggtgc ccggagccgg aatcgaaccg gcacgggatg
     3001 tttagtcccg acggatttta agtccgttgt gtctacctat ttcaccaccc gggcatttgt
     3061 gaaaggtgga ggcgggggcg cggattttaa ccggcctata tgaagattgc actcctcata
     3121 gcataaacac tctgccaccc cgccatagta cgataatgga ggcgagagtc ggaatcgaac
     3181 cggcgtagac ggatttgcaa tccgctgcat aaccactttg ctatctcgcc ctaaaactgg
     3241 cttatctaaa aaacttggag cgggaaacga gtctcgaact cgcgacctca accttggcaa
     3301 ggttgcgctc taccaactga gctattcccg cgcgttcaaa catatcggtt tttggagcgg
     3361 aaaacgagtc tcgaactcgc gacctcaacc ttggcaaggt tgcgctctac caactgagct
     3421 attcccgcgt tgatatgttt gaaataaaac ttggagcggg aaacgagtct cgaactcgcg
     3481 acctcaacct tggcaaggtt gcgctctacc aactgagcta ttcccgcaat gattgtggga
     3541 aaatgaaatt tttggagcgg gaaacgagtc tcgaactcgc gacctcaacc ttggcaaggt
     3601 tgcgctctac caactgagct attcccgccc gatttcattc tccaacatcg aagagacgca
     3661 attattatgg attctgtttt tgccgtcaag ctatttttat gtttttttca ggcgatttct
     3721 ttccacgcca ttttcagata atacagcatc gaccagactg tcagcaaaga tgcgataaac
     3781 atcaatacat tgccgataac aacaagatta aatccgtaaa aatcgggaat attcagcagc
     3841 agcaggaaga ttgccagcat ttgcgcggcg gttttgaact taccgacggt ggcgacggca
     3901 acgctgttcc ttttgcccat ttgcgccatc cattcgcgca atgcggaaat ggtaatttcc
     3961 ctgccgataa tgatcatggc aaacaaaaca taggtccggt cgagtttgac cagtaaaagt
     4021 agcgatacgg caaccatcag cttgtcggcg acgggatcga ggaaggcgcc gaaatcggaa
     4081 gtctgtttcc acagtcttgc caaaaatccg tcaaaccagt cggttaaggc ggcaacggca
     4141 aaaatgacgg cggcggtgag attaatcgtt tcctccgcga accacggaaa aggcaggtaa
     4201 aaaagggctg tcatgacagg aatgagcaag accctcaacc atgtgaggaa gatggggaga
     4261 ttccaaggca tcgattttct ctgtgcagac tgtaaagttg tgattataac ggttatcctc
     4321 ataacccaaa acgtaaaatt gctgcatggg cattcccccg ccccgccaat ctgttttcac
     4381 attcttttca aacgcaggaa aatggcgggc aataaaagca aaatacccag tttcaggctg
     4441 aaaacggcag gttgtgccaa cacttcgaca aggcggtctt ccgtgcgggc aaaatcttta
     4501 ttgcttatag acactgccac tgttgcggta ttccaacaga acgccgttta aaaaaccttt
     4561 gccgacggtt tcgcttaaaa cggctctaac ctgctccgcc ctgatggttc tgccgatatt
     4621 gccgcctgtg cacaaactgt cgaacccata gcaggaaagc cggtaatgct gcccgtctgc
     4681 atccagtttg attgcccgtc cgctgcggtt gggggcggta acggtcaatt ccgcatattc
     4741 taatgttttt tcttgttcgt gaaatgccgt caggtaaggt gcaataaaaa cggcggacaa
     4801 cagcagacag cttatggcgg caaaccatac ccagcgataa tatagtggat taacaaaaac
     4861 cagtacagcg ttgcctcgcc ttagctcaaa gagaacgatt ctctaaggtg ctgaagcacc
     4921 aagtgaatcg gttccgtact atttgtactg tctgcggctt cgtcgccttg tcctgattta
     4981 aatttaatcc actatatttc acgcttaccc cttgtttctc aaatgccgtc tgaaaaaaac
     5041 ggctgtatat gttgtctgca aaatatcggg aagcataaca gacaaaatgc cgtctgaaat
     5101 attttcagac ggcatttcaa tccgattcgg attatttttg cgtttcaacc gcttccaatg
     5161 cacgcagggc gtaagtgtaa gcggcaccgg cattcagggc gatggcggtt gccaatgcgc
     5221 cggcgatttc gctgtcggtc gcaccggctt tggcggcggc ggcggcgtga acactgatgc
     5281 agctctcaca acgtgtggta atggcaacgg cgatggcaat cagttcgcgc gttttggcat
     5341 caagtgcttc ggcggcggcg gcctgttcca atgcgccgta ggcctgcagc attttaggat
     5401 gcgccttacc cagctcgccg aacgattttt taaccaatgc ggtatgttct ttccaatctt
     5461 taaacatttt cttttccttt ctcttgcgtt taaccctgat acgcgcttgc gtatctgttt
     5521 tcgatgtgcg tattattgca attattcagt tgtgtttctc gtttaatcat ctcattttat
     5581 ggttcaaaaa gatttatgga cattctggac aaactggtcg atttcgccca attgacgggc
     5641 agtgtggatg tgcagtgcct tttgggcgga caatggtcgg tacggcatga aaccttgcaa
     5701 cgcgaaggat tggtacacat tgttacatcg ggcagcggct atctctgcat cgacggcgaa
     5761 acttccccgc gtccggtcag tacaggggat attgtatttt tcccgcgcgg cttgggtcat
     5821 gtgttgagcc acgacggaaa atgcggagaa agtttacaac cggatatgcg gcagcacggt
     5881 gcgtttacgg tcaaacagtg cggcaacgga caggatatga gcctgttttg cgcccgtttc
     5941 cgctacgaca cccacgccga tttgatgaac gggctgcctg aaaccgtttt tctgaacatt
     6001 gcccatccga gtttacagta tgtggtttca atgctgcaac tggaaagcaa aaaacctttg
     6061 acggggacgg tttccgtggt caacgcattg tcgtccgtcc tgctggtgct tatcctgcgc
     6121 gcctatctcg aacaggataa ggatgtcgaa ctctcgggcg tattgaaagg ttggcaggac
     6181 aaacgtttgg gacatttaat ccaaaaggtg atagacaaac cggaagacga atggaatgtc
     6241 gacaaaatgg tggcggctgc caatatgtcg cgcgcgcaac tgatgcgccg tttcaaaagc
     6301 cgggtcggac tcagcccgca cgcctttgtg aaccatatcc gcctgcaaaa aggcgcgttg
     6361 ctgctgaaaa aaaacccgga ttcggttttg tcggtcgcac tgtcggtagg ctttcagtcg
     6421 gaaacgcact tcggcaaggc gttcaaacgg caatatcacg tttcgccggg tcaataccgg
     6481 aaagaaggcg ggcaaaaata aatcggggct tcaaacgcaa atgccgtctg aaaaggcttt
     6541 catacagcat ttgcgtaccg cgtcatttca agggctgcat cttcatcact tccatcaaaa
     6601 agttggtaaa tgcggggttg ttgggtttga catccatatt tttccaacgc tgctgccagc
     6661 cgcgcaaggc attctggata tacagcttgg actgttccgt attgattgcg ccccgctggc
     6721 tgtctatcgc cgaacgcagg tagatttcat acatactgtc atcgacggca ttgcgtccga
     6781 ccaggcgttt tctgaagttg ttcagatatt gcgccgcctg aaccttggtc attttaccga
     6841 tacccacctg atagcccaag cgcgtcgctt catcgctgat tttggcaaca tccgtccaat
     6901 gcgaagaggc aaggcggaaa ccttttgcag gtgcttccgt tttgacggta ttgataggat
     6961 tcacggggat ttccgtcaat gtgggcacat aaatagactg gcagccggaa agaactgcca
     7021 caatggaaag agggataagg tattttttca tgcccccatt ataatcaagt ttgccttgag
     7081 aaaacaaatt gttcggcaag aaaaataaaa tttcggcatc agaagcaggc aaaaacacat
     7141 tccacaagcc ttgccgcaag gtttacaatc cgaccgtcct tatcgcaacg accgtttatg
     7201 gataccgcaa aaaaagacat tttaggatcg ggctggatgc tggtggcggc ggcctgcttt
     7261 accattatga acgtattgat taaagaggca tcggcaaaat ttgccctcgg cagcggcgaa
     7321 ttggtctttt ggcgcatgct gttttcaacc gttgcgctcg gggctgccgc cgtattgcgt
     7381 cgggacacct tccgcacgcc ccattggaaa aaccacttaa accgcagtat ggtcgggacg
     7441 ggggcgatgc tgctgctgtt ttacgcggta acgcatctgc ctttggccac cggcgttacc
     7501 ctgagttaca cctcgtcgat ttttttggcg gtattttcct tcctgatttt gaaagaacgg
     7561 atttccgttt acacgcaggc ggtgctgctc cttggttttg ccggcgtggt attgctgctt
     7621 aatccctcgt tccgcagcgg tcaggaaacg gcggcactcg ccgggctggc gggcggcgcg
     7681 atgtccggct gggcgtattt gaaagtgcgc gaactgtctt tggcgggcga acccggctgg
     7741 cgcgtcgtgt tttacctttc cgtgacaggt gtggcgatgt cgtcggtttg ggcgacgctg
     7801 accggctggc acaccctgtc ctttccatcg gcagtttatc tgtcgtgcat cggcgtgtcc
     7861 gcgctgattg cccaactgtc gatgacgcgc gcctacaaag tcggcgacaa attcacggtt
     7921 gcctcgcttt cctatatgac cgtcgttttt tccgctctgt ctgccgcatt ttttctggcc
     7981 gaagagcttt tctggcagga aatactcggt atgtgcatca tcatcctcag cggtattttg
     8041 agcagcatcc gccccactgc cttcaaacag cggctgcaat ccctgttccg ccaaagataa
     8101 aaaatgccgt ccgaacatcc ttcagacggc atatcgggct ttatttcccc gccttcacat
     8161 cctgccactg gcgcaccata aacttcaatg ccgccggctg gataggcacc atgataaagc
     8221 tgtttttcaa atcctcctcg gttgggaaaa tcgtattgtc gtttttaaat tcgtcttcca
     8281 tcagctcacg cgcaggcttg ctcgaaggcg cgtaagtaac gaaattgccg tttttcgccg
     8341 acacttccgg gtcgaggaag tcgttgatgt atttgtgcgc gttggcgacg tttttcgcat
     8401 ctttcggaat cacgaaagaa tccacccaaa tccccacgcc ctctttgggc atcatcacgc
     8461 ggattttttc cttgccgccc gcttcttcgg cacggcgttt ggcgatgttc aaatcgccgc
     8521 cgaaaccgat tgttacgcag gtatcgccgc gcgccaaatc atcgataaag ccggacgaag
     8581 taaagcgttt gatattgggg cggtttttct tgagtagggc ggttgcctcc ctgatgtctt
     8641 ccgtattgct gctgttcggg tttttaccca aatagttcaa caccatagga tagatttccg
     8701 ccgcgctgtc caaatagctg atgccgcatt gcttgagttt ggacgtgtat tcggggtcga
     8761 acaccaaatc ccactggttg tccggcagct tgtccgtacc caaagccttt ttcacgcgtt
     8821 cggtattgat ggcgaaggta tttgtccccc aataaaacgg cacggcgtat tcgtggccgg
     8881 gatcgacccc gtccatcagc ctcatcattt cggggttgag gtgtttataa ttgggaatca
     8941 gcgacttatc gattttctga tacgcacctg ccttaatctg cctgcccaca aacgcattgg
     9001 acggcgcgac aatgtcgtaa ccagattttc cggtcagcac cttgctttcc agcgtttcat
     9061 cgctgtcgta cacatcataa gtaaccttga tgccgttttt cttttcaaaa tcggcaacgg
     9121 tttccggatc gacgtattcc gaccagttgt aaattttcaa tacgtttcgg ttttccgccg
     9181 gcgccggttt ttcggcaggc ggtttgtccg aaccgccgca cgctgcaagc agcaaagcag
     9241 tcaggacggc caggggcaga tgtttggtca ttatcattcc ttgcatatcg ggttggagaa
     9301 agcggccatt atagccgata ttggcaacag ggcttcagac ggcattcaaa atcccgccac
     9361 actcttccga aaaccgccgc ttccatagct agaaacaggg atttgcggta agataccgcc
     9421 gttcgttttc cctgctttta ccatgacaag acatttgaga gacattgaaa aaattatgaa
     9481 aacctccgaa ctgcgccaaa aattcctaaa attttttgaa accaaaggcc acaccgtcgt
     9541 ccgctcttcc agcctcgtgc cgcacgacga cccgaccctg ctgtttacca acgcgggcat
     9601 gaaccagttt aaagacgtat tcttaggttt cgacaaacgc ccgtacagcc gcgccaccac
     9661 cgcgcaaaaa tgcgtacgcg caggcggcaa gcacaacgac ttggaaaacg tcggctacac
     9721 cgcccgccac cacaccttct ttgaaatgat gggcaacttc tccttcggcg actacttcaa
     9781 acgcgacgcc atccacttcg cttgggaatt tctgacttcc cccgaatggc tcaacatccc
     9841 taaagacaaa ctgttggcga ccgtttacgc ggaagacgac gaagcctaca acatctggtt
     9901 gaacgaaatc ggtatgccgt ccgagcgcat cgtccgcatc ggcgacaaca aaggcgcgaa
     9961 atacgtgtcc gacaacttct ggcaaatggg cgacaccggc ccttgcggcc cctgctccga
    10021 aattttctac gaccacggcg aagaaatctg gggcggcatt cccggcagcc ccgaagaaga
    10081 cggcgaccgc tggatcgaaa tttggaactg cgtatttatg cagttcaacc gcgacgaaca
    10141 aggcaatatg aatccgctgc ccaagccgtc cgtcgatacc ggtatgggct tggaacgtat
    10201 ggccgccgtc atgcagcatg ttcacagcaa ctacgaaatc gacttgttcc aagacctgct
    10261 caaagccgtt gcccgcgaaa ccggcgcagc tttcagcatg gatgaaccca gcctgaaagt
    10321 catcgccgac cacatccgct cctgctcgtt cttgattgca gacggcgtgt tgccttccaa
    10381 cgaaggccgc ggctacgtat tgcgccgcat catccgccgc gccgtgcgcc acggttacaa
    10441 actgggtcaa agcaaaccgt tcttccacaa actggtggcc gatttggtca aagagatggg
    10501 cgatgcctac cctgaattga aagaaaaaca agttcaaatc gaagaagcgt tgaaaaacga
    10561 agaaagccgt tttgcccaaa cgctggaaac cggtatggct ttgttggaaa acgcgttggc
    10621 taaaggcggc aaaacactcg acggcgaaat catcttcaaa ctctacgata cttacggttt
    10681 cccatacgat ttgaccgccg acatctgccg cgaacgcaat atcgaactgg acgaagcagg
    10741 cttcgagcgc gaaatggaag cccaacgcgc acgcgcacgc gccgcccaaa gcttcaaagc
    10801 caacgcccaa ctgccttatg acggtcaaga caccgagttt aaaggttata gcgaacgcca
    10861 aaccgaatcc aaagtcctcg ccctctacaa agacggcgag caagtcgacg aattgaacga
    10921 aggcgacagc ggcgcagtcg tcatcgactt taccccgttc tatgcagaat ccggcggcca
    10981 agtcggcgac gtcggctata tcttctcagg cgaaaaccgc tttgaagtac gcgataccca
    11041 aaaaatcaaa gcagccgtat tcggccaatt cggtgtacaa acttcaggcc gtctgaaagt
    11101 cggcgacagc gttaccgcca aagtggacga cgaaatccgc aatgccaata tgcgcaacca
    11161 cagcgcgacc cacctgatgc acaaagccct gcgcgacgta ttgggcgaac acgtcgaaca
    11221 aaaaggctct ttggttaccg ccgaatccac ccgtttcgac atttcccatc cccaagcggt
    11281 aactgccgaa gaaattgccg aagtcgaacg ccgcgtcaac gaagccattt tggcgaacgt
    11341 tgccgtcaat gcagccatta tgagcatgga agacgcgcaa aaaaccggcg cgatgatgct
    11401 tttcggcgaa aaatacggcg acgaagtgcg cgtactgcaa atgggcggtt tctcaaccga
    11461 attgtgcggc ggcacacacg tttcacgcac cggcgacatc ggcctcttca aaatcatcag
    11521 cgaaggcggt attgccgcag gcgtgcgccg tatcgaagcc atcaccggcc tgaacgcact
    11581 caaatgggcg caagagcaag agcgtttggt gaaagacatc attgctgaaa ccaaagccca
    11641 aaccgaaaaa gacgtactgg cgaaaatcca agcaggcgcg gcacacgcca aagccttgga
    11701 aaaagagttg gcaaaagcca aagccgaact cgccgtccac gcaggcgcaa aactcttgga
    11761 cgacgcaaaa gacttgggcg cagccaaact cgttgctgcc caaatcgaag ccgacgcagc
    11821 cgccctgcgc gaaatcgtta ccgatttaac cggtaaatcc gacaacgccg tgattctttt
    11881 agcggcagta aacgacggca aagtctccct gtgcgccggc gtatccaaac cgttgaccgg
    11941 caaagtgaaa gcaggcgatc tggttaaatt tgcagccgaa caagtcggcg gcaaaggagg
    12001 cggccgtccc gacttggcgc aggccggcgg cacggatgcc ggcaaattgc ccgaaatgct
    12061 ggtaagcgtg gaaagctggc tttgtcagaa attaagttaa atttaaatct taataagcca
    12121 tttgagtctt gttcaaatgg cttatatttt ggattgttag aatgaatact aaaacagagt
    12181 tacaaaaact tttagaagag gatatatcaa ctttaacaga aacactaatt tgtgcagatg
    12241 ctcttcctcc aagatatgta cgtagcattg caactcctat tgtccgtcga tggttaattg
    12301 acaaacaatt aaatattctc gcaaaagaaa taggtttaac tatagaattg cccatccttg
    12361 atacaagttt ggtatttgaa aaattgtcaa ccttagagaa taaagttaat ttttatatgg
    12421 ctggtggagt ttatttaggc ggagaattta ttagctctat atatcattca tcacaagaat
    12481 tttctggtga accaataatc tatgctgaac caaatataat tttatgtcct gctgaaaaat
    12541 ttttaacttt aaaacgagtt ttccataatg gaaatatttt taatatgaat cagataatta
    12601 cttttttatc caataaacaa ggaggagtac attttgataa aaattacgat aaatataaaa
    12661 cttggcaagt tgctatagaa aaagcagcaa attttttaaa actcggtaat ccatataatg
    12721 aagataaatt atctcttagt gaagaacatg atactatttt agtagtttta ccattagaaa
    12781 aaggatatga atggaattgt cttgagatag aagtactatc cgctgctcaa tctctagcaa
    12841 atatctattg caacaaagtt cgcctcatag atggtcatgt ttggaaggaa taaaagaaaa
    12901 agcatagttg gtaattttta gttacgtagg gtgggcttca gcccaccgtt ttttcatttt
    12961 tgattgttga ttggtgggct aaagcccacc ctacggttac taaaatcccg tcattacctc
    13021 gcaggcggga atccggtttg ttcggtttcg gttttttagg gacagtgccg caacattaaa
    13081 tttccagatt cccactttcg cacaaataac agcgcaaata gggcaaagat aaggatatgg
    13141 gtttttttct ttgaatttac tatacaattc gcccgtcccc gttatagaaa cccaagccga
    13201 tgaaaaccct gctccaactc caaaccgccg cacaaaactt cgccgcctac tacaaagacc
    13261 aaaccgacga acgccgcgag aaagacacct tctggaacga atttttcgcc attttcggca
    13321 tcgaccgcaa aaacgtcgcc cacttcgaat accccgtcaa agaccctgcc gacaacaccc
    13381 aattcgtcga tatattttgg gagggcatct tccttgccga acacaaatcc gccaacaaaa
    13441 acctgaccaa ggccaaagag caggcggagc gttatttgca ggaaatcggg cgcaccaagc
    13501 cctctgcgct gcccgaatat tacgccgtca gcgattttgc ccatttccac ctttatcgcc
    13561 gcgtacctga agaaggcgtg gaaaaccaat ggcagttccc tttggaagca ttgcccgaat
    13621 acatcacgcg cggcgttttc gacttcatgt tcggcatcga agccaaagtc cgccaaattc
    13681 aagaagaagc cgatattcaa gcggcggcgg ccatcggcag gctgcacgac gcgctcaaag
    13741 aagaaggcat ttacgaagaa cacgagctgc gcctcttcat cacgcgcctg cttttcctct
    13801 tttttgccga cgacagcgcc gttttccagc gcaactatct ctttcaagac tttttagaaa
    13861 gctgcaaaga aaccgacacg ctcggcgaca agctcaacca actctttgaa ttcctcaaca
    13921 cacccgacca aaagcgcagc aagacccaaa gcgaaaaatt taaaggtttc gaatacgtca
    13981 acggcggcct gtttaaagaa cgcctgcgca ccttcgactt caccgccaag cagcaccgcg
    14041 ccttaatcga ctgcggcaat ttcgactggc gcaacatgag acctttgcaa taacataggt
    14101 tactaaaatt ttatgctcaa tctcattttc aaaatgcaaa acttttctga tttttcctac
    14161 tttttgctca atattaggaa ggttttaggc aattgaaaat tttttggcgc atttttatgc
    14221 gtcaaatttc gttaacagac tatttttgca aaggtctcaa catcagtccc gaaatcttcg
    14281 gcacgctctt ccaatcagtc atggacgcac aagagcggcg cgaagcgggc gcacactaca
    14341 ccgaaaccgc caacatcgac aaagtcatca acggcctttt tttagaaaac ctgcgcgccg
    14401 aatttgaagc cgtcaaagcc ctcaaacgcg acaaagacaa aaaactcgcc gccttctacc
    14461 aaaaaatcca aaacctgcaa ttcctcgacc cggcctgcgg ctgcggcaac ttccttatcg
    14521 tcgcctacga ccgtatccgc gccctcgaag acgacatcat cgccgaagcg ctcaaagaca
    14581 aaacaggcgg cttattcgac agcccgtccg tccaatgccg tctgaaacag tttcacggca
    14641 tcgaaataga cgaatttgcc gtcctcatcg cccgcaccgc catgtggctc aaaaaccacc
    14701 aatgcaacat ccgcacgcaa atccgcttcg acggcgaagt cgcctgccat acgctgccgc
    14761 tcgaagacgc cgccgaaatc atccacgcca acagcctccg cacaccttgg caggcggcgg
    14821 actacatctt cggcaatccg ccctttatcg gctcgaccta ccaaaccaaa gagcagaaaa
    14881 acgacctcga aagcatctgc ggccatatca aaggctacgg cctgttggat tacgtctgca
    14941 actggtatgt caaagccgcc ggtatcatgg cgcagcatcc ccaagttcag acggcatttg
    15001 tttccaccaa ttccatctgc caaggccagc aggtcgaaat cctttggggc agccttttga
    15061 agcaagacat cgaaatccac tttgcccacc gcacctttca atggacgagc caagccgcag
    15121 gcaaagccgc cgtccactgc atcatcgtcg gcttccgcca aaagccgcaa atgccgtctg
    15181 aaaaaaccct ctacgactat cccgacatca aaggcgaacc cgtaaaacac gccgcggcca
    15241 acatcaatcc gtatctgatt gacgcgcccg atgtgattat tgccaagcgc agccgtcccg
    15301 tacattgcga acctgacatg gtcaacggaa gcaaaccgac cgaaggcggc aaccttatcc
    15361 tttcaaccga tgaaaaagaa gccctgattg ccgccgaacc cttggcggaa caatacatcc
    15421 gtccctttgt cggcgcagag gaatttatca acggcaaaac ccgttggtgc ctgtggtttc
    15481 acggcgtatc cgacgttaaa cgcaaccacg acctgaaaca gatgccccaa gttcaagccc
    15541 gtattcaggc agtcaaaacc atgcgcgaag ccagcagcga caaacaaact caaaaagatg
    15601 cagcaacccc gtggcttttt caaaaaatcc gccagccttc agacggcaat tttctgatta
    15661 tcccacgcgt ctcatccgaa agccgccgtt tcgtccccat cggttatcta tcatatgaaa
    15721 cagttgtcag cgatttggta tttacccttc caaacgccag cctctaccac ttcggcatcc
    15781 tcagctccac catgcacaac gcctttatgc gtaccgttgc cggccgtctg gaaagtcgtt
    15841 accgctattc caataccgtt gtgtacaaca acttcccctt ccccgaaagc tgccggatgc
    15901 cgtctgaaaa cgaccgccaa gacccgctcc gcgccgccgt cgaaaccgcc gcccaagccg
    15961 tcctcgacgc gcgcggacaa taccgccgag aagcgcggga agccggtttg cccgagccga
    16021 ccctcgccga actctatgcg cccgacgcag gctataccgc cctagacaaa gcccacgccg
    16081 ccctcgacaa ggcagtcgat aaagcctacg gctacaaaac aggcaaaaac accgacgacg
    16141 aagccgaacg caccgccttc ctgttcgagc tgtaccgcaa ggcggcggca attgcgtagt
    16201 agttgcgtag tagttgcgta gtagttgcgt agtagttgcg tagtagttgc gtagtagttg
    16261 cgtagtagtt gcgtagtagt tgcgtagtag ttgcgtagta gttgcgtagt agttgcgtag
    16321 gatagttgcg tagggtgggc ttcagcccac caactcccac caactcccac catcttcacc
    16381 ctaaaacccc gtcatctccg caaaagcaat tgcgtagggt gggcttcagc ccaccgtttt
    16441 tcttcatttt cggttgttga ttggcaggct gaagcccacc ctgcggttac aaaaatcccg
    16501 tcattcccgc gcaggcggga atccagacct ttcggggcgg aaacttatcg gataaaacga
    16561 tttcccctgc atcctggatt cccactttca tgggaatgac gggatatagg tttccctacg
    16621 gacgtgttca gattcccgcc ttcgcgggaa tgacggcgga gaagtttctg tctttccgat
    16681 aacttaccgt aacttaaaat cccgtcatta ccgcaaaagc agttgctacg gttacaaaaa
    16741 tcccgtcatc cccacgaaag cgaaaatcct gcctgtcgga tttcggtttt ttcgggcgtt
    16801 tcgggaactt ataaatcgtc attcccgcgc aggcgggaat ccagaacgcg ggacggcggc
    16861 aatattcaaa ggttgtctga aaattcagag gttctagatt cccgcctgcg cgggaatgac
    16921 ggcggagcgg tttctgcttt tccgataaat gaccgcaacc taaaacccat ccttcccacg
    16981 aaaacagaaa aacaaaaacc taaaatcccg tcgttctcgc gaaagcagtt gctacgttta
    17041 ccgtcaaaaa tgccgtctga acgctcaagc cttcagacgg cattttttat ttcacaccct
    17101 tacaggtaga atttttcgat gactttcaaa ttgtcgtcca atttgtacac caacggctga
    17161 ccggtcggga tttccaagcc catgatgtct tcgtcggaaa tgccctcgat gtgttttgcc
    17221 agcgcgcgca gggagttgcc gtgcgccgcc accaagacgc gtttgccgct caaaatcgcg
    17281 ggggcgattt ggtcttccca aaacggcaat acgcgctcca gcgttacttg caggttttcg
    17341 ccgtcgggga taacatcggc aggcagatgg gcatagcggc ggtctttgtg tgcggaaaac
    17401 tcatcgtctt tgtccaaaag cggcggcagg gtgtcgtagc tgcgccgcca gatgcggact
    17461 tgctcgtcgc cgtattgttc ggcggtttgt tttttgtcca ggccttgcag tcggccgtag
    17521 tggcgttcgt tcagccgcca tgttttgatt tgcggtacga acagttggtc ggattcttcc
    17581 aaaacgatgt tgcaggtctt aatcgcgcgg gtcaggacgg atgtgaaggc gatgtcgaac
    17641 tcatagccgt tttctttcag ttttttaccg gcggcagcag cctcggcaag cccctgctcg
    17701 ctcagcttca cgtcgcgcca gcctgtaaac aggtttttcg cgttccattc gctttgtccg
    17761 tggcggataa ataccaattc catatcgtct ccaatgtgtg aaagtgggaa agccttattt
    17821 ataacatatt ttcacattcc cgtatttgat tcagattcag acacgcgccc actatggttt
    17881 gccgttttga tttacaataa tgccctttgc tttacattcc gcatacacaa tgtttcaaca
    17941 cacaggacga cacataaagc accgccctat gtgttgccct gatttggaag gggttgcccc
    18001 ctcccaaata aagtctgatt ctaccgcccc gaaggacaga tgtccaagtg gcgggggttc
    18061 aaccgaaaag gaaatacgat aaatatgcaa ccgcacgctc cacataccga ttccaatacg
    18121 ctgatgctcg gtcaatacgc cgaacgcgcc tatctcgaat acgccatgag cgtggtcaaa
    18181 ggccgcgcgc tgcctgaagt ttcagacggc cagaagcccg tgcagcggcg cattttgttt
    18241 gccatgcgcg atatgggttt gacggcgggg gcgaagccgg tgaaatcggc gcgcgtggtc
    18301 ggcgagattt tgggtaaata ccacccgcac ggcgacagtt ccgcctatga ggcgatggtg
    18361 cggatggcgc aggattttac cttgcgctat cccttaatcg acggcatcgg caacttcggc
    18421 tcgcgcgacg gcgacggggc ggcggcgatg cgttacaccg aagcgcggct gacgccgatt
    18481 gcggaattgc tgttgtccga aatcaatcag gggacggtgg attttgtgcc gaactacgac
    18541 ggcgcgtttg acgaaccgct gcacctgccc gcccgcctgc ctatagtgtt gctcaacggc
    18601 gcgtcaggca ttgcggtggg catggcgacc gagattccgt cgcacaattt gaacgaagtg
    18661 acgcaggcgg cgattgcgtt gttgaaaaag ccgacgctgg aaaccgccga cctgatgcaa
    18721 tacattcccg cacctgattt tgccggcggc ggtcaaatca tcacgccggc ggacgaattg
    18781 cgccggattt atgaaaccgg caagggcagt gtgcgcgtgc gtgcgcgtta tgaaatcgaa
    18841 aaattggcgc gcggacaatg gcgcgtcatc gtaaccgagc taccgccgaa cgccaattcc
    18901 gccaaaatcc ttgccgaaat cgaagagcag accaacccga aaccgaaagc gggcaaaaag
    18961 cagctcaacc aagaccagct caataccaaa aagctgatgc tggatttaat cgaccgcgtg
    19021 cgcgacgagt ccgacggcga acatcccgtg cgactggtgt tcgaaccgaa atccagccgc
    19081 atcgataccg ataccttcat caacacgctg atggcgcaaa cttcgctgga aggcaatgtg
    19141 tccatgaact tggtgatgat ggggctggac aaccgccccg cgcagaaaaa cctgaaaacg
    19201 attttgcagg aatggctgga tttccgcacc gtaaccgtaa cacgccgtct gaaattccgt
    19261 ttgaaccaag tggaaaaacg gctgcacatc ctcgaaggcc gtctgaaagt ctttctgcac
    19321 atcgacgaag tgattaaagt catccgcgaa tcagatgacc cgaaagccga tttgatggcg
    19381 gcgttcgggc tgaccgaaat ccaagccgaa gacattttgg aaatccgcct gcgccagttg
    19441 gcacgtttgg aaggtttcaa actcgaaaaa gaattgaacg aattgcgcga agaacaaggc
    19501 cgtctgaaca tccttttggg cgatgaaaac gaaaagcgca agctgattat caaagagatg
    19561 caggcggata tgaaacaata cggcgatgca cgccgcacgc tggtggaaga ggccggacgc
    19621 gccgtgctga cacaaaccac cgccgacgaa cccatcacac tgattctgtc ggaaaaaggc
    19681 tggatacgca gccgtgccgg acacaatctc gatttgagcc aaaccgcgtt caaagaaggc
    19741 gaccgcctca aacaaaccct tgaaggcaga acggttttac ccgtcgtcat cctcgattca
    19801 ttgggcagaa cctatacact cgatgccgcc gaaattcccg gcggacgcgg cgacggcgtg
    19861 ccggtttcat ccttgatcga gttgcaaaac ggcgcgaaac ccgttgcgat gttgacagga
    19921 ttgccggaac aacattattt attatcaagc agcggcggct acggcttcat cgccaagttg
    19981 gctgatatgg tcggacgcgt aaaagcgggc aaagtggtga tgaccacaga cagtggcgaa
    20041 accgtcctgc cgccgattgc cgtctatgcc tcctcgttca tcaaccccga ctgcaaaatc
    20101 attgccgcca ccagtcaaaa ccgcgccctc gccttcccca tcggcgaatt gaaaattatg
    20161 gcgaaaggca aagggctgca aatcatcgga ttaaacgccg gcgaatcgct gacgcatacc
    20221 gccgtttctt ccgagccgga aatcctgatt gaaagcgaag gcaggcgcgg cgcggcgcac
    20281 aaagaccgca tccccgtctc cctgcttgag gcaaaacgcg gcaaaaaagg caaactatta
    20341 cccatatcgg gcagcctgaa acagctttct tcccccaaat aaacccgatt ccacacataa
    20401 ttatggtgat ttccaacccc cgcgaacttg aaaaactcaa agaccggatt cccaatctga
    20461 tcaacatcat ccgcgtcgcc atcgtttttc cgctgatgat tatgcacatc ctcgggctgg
    20521 aaaccggcag ccgtgcgaac ctgcacgctt cgtggacggc gtgggcgttt tatgtttggc
    20581 tcgccattgc ctgctggctg attttctttt ccatcatcca tccgcattgg caatggcagg
    20641 ctttgagaat accgagtttc agcgcggtgg cggacatcac gatgatcggc gtgctgacct
    20701 acctgttcgg cggcatcgac tccggcttcg gcatcctgat tctgcccttc gtcgtctgct
    20761 cctgcctgct cagctacggg cgctaccccc tgctctattc cagctacgcc gccatcctgc
    20821 tgatattcaa cgccattgcc gacggcgata tcggcaaata cccgctcata tcggatgccc
    20881 gaaccgcctc ggcaaccttc atccttgtcg ccgcctccta tctttccgcc atcttcacct
    20941 cgctgtcggt cagatacatc gaccgtgccg gcaaacttgc ccgcgacaac cacctcgcct
    21001 accggcgcat caaaggcttg agccaaaccg tactcgaacg cgttcaagaa gccgtcgtcg
    21061 tcatcaatac cgaagggctg gcggtgctgt tcaaccggaa ggcgaaagac cttttccccg
    21121 cactcgaaat cggacggcgc gccgacctgt ccgattctgc cgccgaactg tgggaccaag
    21181 cctctccgca cactttcgaa aacgtcctcg gcacactcgg cctgaccgcc cgcatccgcg
    21241 ccgttccggt caacaaaggg ccggacaagc tgctcatcct ctacatccgc ccgcaaagcg
    21301 aaattcaggc agaagccctg tccgtcaaac ttgccgcgct cggacaactg accgccaacc
    21361 ttgcccacga aatccgcaac ccgatgtccg ccatccgcca cgccaacgac ctgctgcgcg
    21421 aaaatatgga agcgggggcg gcagatccgt tcaacgccaa attgtgcaaa atcatcgacg
    21481 gcaacgtctg ccgtatcgac aaaatgctcg aagatatttc ctcgctcaac aagcgcaaca
    21541 aaaccgaacg cgaagccatc ggcctgatac cgttttggga agaattcaaa caagagttcc
    21601 tgctcggcca tcccgatgcc gccggctgca tccgcctaga tatgcagggc aatcacctga
    21661 ccgcctattt cgatcccgcc cacctgcggc aaattatgtg gaacctcgcc aacaacgcgt
    21721 ggcggcacag ccgcaaacag cccggctcga tttccgtcac catccgcccc gcgcaaaaaa
    21781 acaccgtctg tatcctcttt gccgaccgcc cgaagtgcag gaacacctgt tcgaaccctt
    21841 ttacaccacg gcggaaaacg gcaccggcct cgggctgtat gtcgcccgcg aactggcgca
    21901 cgccaatttc ggcgatttga cctacctacc ggaagccaaa tgtttcgaac tcacattacc
    21961 ggaaaaaacc aatgactgaa ctgcaacacc ccgtcctcgt cgtcgatgac gaaaccgaca
    22021 ttctcgacct gatggaaatg accctgatga aaatgggctt gcgcgtccat accgcgtcag
    22081 gcgttgccga agccaaaaac aagctcgaca gccaacgcta ttcgctcgtc ctgaccgata
    22141 tgcgtatgcc ggacggctcg gggctggaag tcgtccaaca catcaacagc cgcctgctcg
    22201 atacgccggt tgccgtcatc accgccttcg gcaacgccga tcaggcacag gaagcgttgc
    22261 gttgcggcgc gttcgacccc gataccatgc agatacagga ctatctcgac caaatcgaac
    22321 gcgacattat cgaacaaacc ctcaaacaaa ccgaaggcaa ccgcacgcag gccgccaaac
    22381 gcttgggcat cagcttccgt tccatgcgct accgtatgga acgcctcaac atcggctgac
    22441 gacaaaacgg catccgcacc atctccgccc acccgaaaaa atgccgtctg aaacggcacg
    22501 ggaaagcggg ttcgccccac gcccgaacgg acacaaaaca ccatgaccga catccttatt
    22561 gacaacaccg ccaccgaaac cgtccgcacc ctgatacggg cattccccct tgtgcccgtt
    22621 tcccaaccgc ccgaacaagg cagttacctc cttgccgaac acgataccgt cagcctcagg
    22681 cttgtcgggg aaaaaagcag cgtcatcgtc gattttgcct ccggcgcggc acaataccgg
    22741 cgcacaaaag gcgggggcga actcatcgcc aaagccgtca accacaccgc gcaccccacc
    22801 gtttgggacg caaccgcagg attggggcgc gacagcttcg tcctcgcctc gctcgggctg
    22861 gccgttaccg ccttcgagca acatcccgcc gtcgcctgcc tgctttcaga cggcatccgc
    22921 cgcgccctcc tcaatcccga aacgcaagac accgccgcgc gcatcaacct ccatttcggc
    22981 aacgccgcag tacaaatgcc cgcccttgtt caaacacaag gcaaacccga catcgtctat
    23041 ctcgacccca tgtatcccga acgccgcaaa agtgccgccg ttaaaaaaga aatgacctac
    23101 ttccaccggc tcgtcggcga agcgcaagat gaagcggcac tcctgcatac cgcacgccaa
    23161 acagcaaaaa aacgcgtcgt cgtcaaacgc ccccgcctcg gcgaacacct tgccggacaa
    23221 gcccctgcct accaatacac cggcaaaagc acccgcttcg acgtttacct gccctacggg
    23281 acggacaagg gataacgccc ataaaacaag acaccgaaaa atttgccgtt cttatgcaaa
    23341 cgagaaaccg gtttttgcgt ttcgactgtt ttggataaat catcacacct taaagtttgt
    23401 cattcccacg gaagtgggaa tccagaaatg aaaagcaaca ggaatttatc gtaaatgacc
    23461 gaaaccgaac ggactagatt cccgcctgcg cgggaatgac ggggcgggcg gatgccgtct
    23521 gaaattccgt cattcccgta aaaacgggaa tctagaactt ctgatttttc agacgacttt
    23581 tgaacattgc cgccacccaa tgatctggat tcccacctgc gcgggaatga cgaggtttca
    23641 ggttgctgtt tttaagttgc tgtttcgggt tgctgttttt tatggaaatg acgaggtttt
    23701 agattgcgag aatttatccg ctccgccgtc attcccacgg aagtgggaat ctagaaatga
    23761 aaggcaacag gaatttatcg taaatgaccg aaaccgaacg gactagattc ccgcctacgc
    23821 gagaatgaca aggtttcagg ttgctgtttc gggttgctgt tttttatgga aatgacgagg
    23881 ttttagattg cgagaattta tccgctccgc cgtcattccc acggaagtgg gaatcaggaa
    23941 atgaaaagca ataggaattt atcgtaaatg accgaaaccg aacagactag attcccgcct
    24001 gcgcgggaat gacggggcgg gcggatgccg tctgaaattc cgtcattccc gtaaaaacgg
    24061 gaatctagaa cttctgattt ttcagacgac ttttgaacat tgccgctacc caatgatctg
    24121 gattcccacc tgcgcgggaa tgacgatgta aaattatccg ggattcaaaa agacaggctt
    24181 tcgcatccgt gggaatgact gcggaaagat gatttttata gtggattaaa tttaaatcaa
    24241 gacaaggcga cgaagccgca gacagtacaa atagtacggc aaggcgaggc aacgccgtac
    24301 tggtttttgt taatccacta tattttgtca taaaaatccg caccttaatc agttggcggt
    24361 taaatcaaac ttttagggtg cagattactt tttatgattt cagacggcat tttgacagac
    24421 cgcaaaccta tttcggcaat accaaaaact taatcaataa ctctttgaac acaaaaccaa
    24481 acacgcccaa gcccaaaacc aaaaacaaaa tggcgatgcc gaatttgccc gctttagact
    24541 ccttgcccaa attccaaacg ataaaaccca aaaaaataat caagccggtc aggcagattt
    24601 tcaacgccca atcggcaaaa accgcttcat ccatattttt ttcctattgt tgacgtgtat
    24661 gtcatataag ataagggttt cagacggcat ttgcggtgtt tttccgccga tgccgtctga
    24721 acacgcaatc agcgcgcgag tgcctgtttc aaatcgtcaa tcaaatcgcc aacatattcc
    24781 aaaccgaccg acaggcgcac caatccgggg cggatgttgg cggcgagttt ttcttcgggc
    24841 tgcatcctgc cgtgcgtggt tgtccacgga tgggtaatgg tcgagcgcac gtcgccgagg
    24901 ttggcggtac gggagaaaag ttcgacgccg tccacgactt tccacgcggc tgcttggtcg
    24961 gcgacttcaa agccgatgac gatgccgccg ccgttttgct gtttgcggat aagctccgcc
    25021 tgaggatggt cgggtaatcc ggtgtaatac acggcttgaa cctgcggctg cgcttgcagc
    25081 cattgcgcga ttttcaaggc gttgtcgaac tgtttttcca tacgcagaga cagggtttcc
    25141 acgccgctca acaactgcca tgcgttaaac ggcgacattg ccagcccgca agagttgcag
    25201 taaacggcga cctgcgccat cagttcttcc gaacccgcca acacgccgcc catcacgcgc
    25261 ccgtgtccgt ctatggcttt ggtcgcggag gaaacggaaa tatccgcgcc gtgtttcaaa
    25321 ggctgagagc cgacaggcga cagcaggctg ttgtccacca ccaagagcgc gccgatgccg
    25381 tgcgccaatt ccgccaaggc ttccaagtcg gccacttctc ccaagggatt ggacggcgtt
    25441 tccaaaaaca gcagtttggt gttggctttg acggcggctt tccattcgtt tatatcagtc
    25501 ggcgacacgt gactcacttc gatgccgaat ttggtaacga tgttattgat aaagccgacg
    25561 gtcgtgccga acaggctgcg gctggaaatc acatggtcgc ccgcctgcaa aaaggtgaaa
    25621 aacgccgcct gaatcgcgga catgccggtc gaagtggcga ccgcgcgttc cgcaccttcc
    25681 aaagcggcga tgcgtttttc aaaggcggct gtggtcgggt tggcggtacg ggtataagtg
    25741 aagcctttga ttttttttga aaacaaatcg gcagcgtgtt gggcgttgtc ccacatgaaa
    25801 ctgctggtca ggaacaatgc ctgattgtgt tcgcggtatc cggtttgttc tttgccgccg
    25861 cgtatggcga gcgtttgcgg atggagtttt ttgctcatcg gtgattcctc ggttttatcc
    25921 gttcggcaac ggagcgtgcg cccgttgttt aatttatagt ggattaacaa aaaccagtac
    25981 agcgttgcct cgccttagct caaagagaac gattctctaa ggtgctgaag caccaagtga
    26041 atcggttccg tactatttgt actgtcttcg gcttcgtcgc cttgtcctga tttttgttaa
    26101 tccactatat taatattttg cgcccgttcc gtgaggcttt caagtcggat gagaatgcaa
    26161 atgccgtctg aacacggctt tcagacggca tgacggtcag cgtttgtatt ttaactcgta
    26221 cttgatgtcg ttgaggattt tgcggacatc gtgttccaac acgtcttcga ccaccgcgcc
    26281 cgcctgatcg tgcagcattt gctggagctg ataagtaaag agtgccatct gcttttgcac
    26341 cgccgttcga atgatgccgt tgacggtatc ggtcagatgc ggacgcaggc gtttgatcag
    26401 ccgttcggtc agctcctgtt cggacaggca gaacacttcg cgccggttga cggctttcgg
    26461 gttcaggata ttgatttgga cgggcatcaa cgcctcttcc gcaccgcctt cgccgttttc
    26521 cgcaaccccg tctgccgccg tacccgattc tgccgcatcg gcgttttccc cgccttcaat
    26581 ctgtccggtt tcaaattcgg cactgtcttt tttggcatcg aacaggattc tccgccgcga
    26641 ttcgatgtgt ttttccgaaa ccgacatttg cagggaagcc tgcgcgttga gccagttttc
    26701 ctgaaggaca atcatcgggt cggtttcgac ttcctcgccg caatcggcaa cggcggcatt
    26761 gtgttcctcc tgccattttt tcagatacgc cttcaacaca tggtctcggc tctcatcgtc
    26821 cagtttcggc acaggcgcgt ccgttccggt ttcagagggg cgggacagcg gcgcgtaagt
    26881 cggcactgcc ttcatacggc gcgtctgacg caggttttcc aaacgttttt cccaattcgg
    26941 ctctttattc acatccattt tcggcttccg gttcttaatc tttgcaggca gacaaacccg
    27001 cgcccaaagc gcggtttgat ataatggcgc attttaacag attcgcgagg atacatcatg
    27061 ggcagcatcg aacagcgttt ggaatatctg gaagaggcga acgacgtgct gcgtatgcag
    27121 aaccacgtcc tgtccaccgc attcaaagcc ttaatccgcg cccttcccgc cgaaaccgcc
    27181 gaaatcgcgg tcgagtcgat tcagcttgct tttgaggacg ccttggcaga attgagctat
    27241 gaggacagcc cccataccga tttgttccac gacgttactt atgcgttttt ccgtgaaaaa
    27301 gaacgttaat tttatgttaa actgattttt taggcttttt gattaccgaa aggaattttg
    27361 atgaatatga aaaaatggat tgccgccgcc cttgcctgtt ccgcgctcgc gctgtctgcc
    27421 tgcggcggtc agggtaaaga tgccgccgcg cccgccgcaa accccgacaa agtgtaccgc
    27481 gtggcttcca acgccgagtt tgcccccttt gaatctttag actcgaaagg caatgtcgaa
    27541 ggtttcgatg tggatttgat gaacgcgatg gcgaaggcgg gcaattttaa aatcgaattc
    27601 aaacaccagc cgtgggacag ccttttcccc gccttgaaca acggcgatgc ggacgttgtg
    27661 atgtcgggcg taaccattac cgacgaccgc aaacagtcta tggacttcag cgacccgtat
    27721 tttgaaatca cccaagtcgt cctcgttccg aaaggcaaaa aaatatcttc ttccgaagat
    27781 ttgaaaaaca tgaacaaagt cggcgtggta accggctaca cgggcgattt ctccgtatcc
    27841 aaactcttgg gcaacgacaa cccgaaaatc gcgcgctttg aaaacgttcc cctgattatc
    27901 aaagaactgg aaaacggcgg cttagattcc gtagtcagcg acagcgcggt catcgccaat
    27961 tatgtgaaaa acaatccgac caaaggaatg gacttcgtta ccctacccga cttcaccacc
    28021 gaacactacg gcatcgcggt acgcaaaggc gacgaagcaa ccgtcaaaat gctgaacgat
    28081 gcgttgaaaa aagtacgcga aagcggcgaa tacgacaaaa tctacgccaa atattttgca
    28141 aaagaagacg gacaggccgc aaaataagcc cgcccatccg aacacaatgc cgtctgaagc
    28201 cctttcagac ggcattgttc atcaatcggc ctacaatgaa ctgcctgctg atttctccct
    28261 accgcaaagc aacaggcaaa gattacaaat atcaaaatcc gagtaaaaca gtattttatt
    28321 aaaacaaatt gataatcaag agattagaat tatgtattgt ctttaccgta caaacgctgg
    28381 cactatttca acctgataaa aaacagcctt caaaaaggtt gcttaaaaca acagcagaca
    28441 cttaccgcca caaccttgaa aaggaacaca atcatgaccg tcatcaaaca ggaagacttt
    28501 atccaaagca tttgcgatgc cttccaattc atcagctact accatcccaa agactacatc
    28561 gacgcgctct ataaagcgtg gcagaaagaa gaaaaccccg ccgccaaaga cgcgatgacg
    28621 cagattttgg tcaacagccg catgtgtgcc gaaaacaacc gccccatctg ccaagacaca
    28681 ggtatcgcaa ccgtgttttt gaaagtcggt atggatgtgc agtgggatgc ggacatgagc
    28741 gtggaagaaa tggttaacga aggcgtacgc cgcgcctaca cttgggaagg caatacgctg
    28801 cgcgcttccg ttctcgccga cccggccggc aaacgtcaaa acaccaaaga caacacgccc
    28861 gccgtcatcc atatgagcat cgtgccgggc gacaaagtcg aagtaacctg cgcggcaaaa
    28921 ggcggcggtt ctgaaaacaa atccaaactc gccatgctca atccttccga caacatcgtc
    28981 gattgggtat tgaaaaccat cccgacgatg ggcgcgggct ggtgtcctcc cggcatcttg
    29041 ggcatcggca tcggcggcac gcctgaaaaa gccgtgttga tggcaaaaga gtccctgatg
    29101 agccacatcg acatccaaga attgcaggaa aaagccgcgt ccggcgcgga attgtccacc
    29161 accgaagccc tgcgcctcga actctttgaa aaagtcaacg cgctgggcat cggcgcacaa
    29221 ggtttgggcg gtctgaccac cgtgttggac gtgaaaatcc tcgattaccc gacccacgcc
    29281 gcctccaaac cgattgccat gattccgaac tgcgccgcca cccgccacgt cgaatttgaa
    29341 ttggacggct caggccctgt cgaactcacg ccgccgcgcg tcgaagactg gcccgatttg
    29401 acttacagcc ccgacaacgg caaacgcgtc gatgtcgaca agctgaccaa agaagaagtg
    29461 gcaagctgga aaaccggcga cgtattgctg ttgaacggca aaatcctcac cggccgcgat
    29521 gccgcacaca aacgcctcgt cgatatgctc aacaaaggcg aagaattgcc cgtcgatttc
    29581 accaaccgcc tgatttacta cgttggtccc gtcgatccgg tcggcgatga agtcgtcggt
    29641 ccggcaggtc cgaccacagc cacccgcatg gacaaattca cccgccaaat gctcgaacaa
    29701 accgacctct tgggcatgat cggcaaatcc gagcgcggcg tggccacctg cgaagccatc
    29761 gccgacaaca aagccgtgta cctcatggca gtcggcggcg cggcgtatct cgtggcaaaa
    29821 gccatcaaat cttccaaagt cttggcgttc cccgaattgg gcatggaagc catttacgaa
    29881 tttgaagtca aagacatgcc cgtaaccgtc gccgtagaca gcaaaggcga atccatccac
    29941 gccaccgccc cgccccaatg gcaggcgaaa atcggcatca tccccgtcga atcttgaggc
    30001 gccatgccgt ctgaacacaa aatctgcctt cagacggcat ttccgccccc ggttgcggta
    30061 caatccacca tttcatcact cggcgaccca caccgtgaaa atcctcattt taggcaacgg
    30121 acaggtaggt tctaccgtcg cacaaaacct tgccgccata cccaacaacg acgtaaccgt
    30181 tatcgacatc gacgaaaaag cattgcagga aacaggcagc cgcctcgatg tccaaaccgt
    30241 tttcggcaac ggcgcatccc ccttcacatt agaacgcgcc ggcgcggaag atgccgactt
    30301 gctgctcgcg ctctcccgca gcgacgaaac caacatcgtc gcctgcaaag ttgccgccga
    30361 cctgttcaac atccccggcc gcatcgcgcg cgtccgttcc agcgaatacc tcgaatacct
    30421 cagccccaag ctcgaaaaca acgaaaacgg cagcctttcc atattcggca taaccgaaac
    30481 catcagcccc gaacagctcg ttaccgaaca gcttgccggc ctgatagact gcccgggcgc
    30541 attgcaggtt ttacgttttg cagacgaccg cgtgcggatg gtcatcatac aggcgcggcg
    30601 cggcggactg cttgtcggac gcagcattgc cgacatcgcc caagatttgc ccgacggggc
    30661 cgactgccaa atctgcgccg tttaccgcaa caaccgcctc atcgtccccg cgccgcaaac
    30721 cgtcatcatc gaaggcgacg aaatcctatt tgccgccgcc gccgaaaaca tcggcgcggt
    30781 catacccgaa ttgcgcccca aagaaaccag cacccgccgc atcatgattg ccggcggcgg
    30841 caacatcggc taccgtctcg ccaagcagct cgaacacgca tacaacgtca aaatcatcga
    30901 atgccggtcg cgccgtgccg aatggatagc cgaaaacctc gacaacaccc tcgtcctgca
    30961 aggttcggca accgacgaaa ccctgctcga caacgaatac atcgacgaaa tcgacgtatt
    31021 ctgcgccctg accaacgacg acgaaagcaa cattatgtcc gcccttttgg cgaaaaacct
    31081 cggcgcgaag cgcgtcatcg gcatcgtcaa ccgctcaagc tacgtcgatt tgctcgaagg
    31141 caacaaaatc gacatcgtcg tctcccccca cctcatcacc atcggctcga tactcgccca
    31201 catccggcgc ggcgacatcg ttgccgtcca ccccatccgg cgcggcacgg cggaagccat
    31261 cgaagtcgtc gcacacggcg acaaaaaaac ttccgccatc atcggcaggc gcatcagcgg
    31321 tatcaaatgg ccagaaggct gccacattgc cgccgtcgtc cgcgccgaaa ccggcgaaac
    31381 cattatggga caccataccg aaaccgtcat ccaagacggc gaccacatca tctttttcgt
    31441 ctcgcgccgg cgcatcctga acgaactgga aaaactcatc caggtcaaaa tgggcttttt
    31501 cggataaacc gccccattcc ggacatattg ccgccaagcg gtatggaagc agaaataatg
    31561 gtaggtgggc ttcagacggc atccgccctc cccgtcattc ccgcgcaggc gggaatctag
    31621 accttgggat agcggcaata ttcaaaggtt atctgaaaat ttagaggttc tagattcccg
    31681 ttttcacggg aatgacgaag agttgcggga atctagacca ttggaaagcg gcaatattca
    31741 aaggttagct gaagctttag aggttctaga ttcccgtttc cacgggaatg acgaaaggtg
    31801 gcgggaatcc agaacgtcgg gcaacggcaa tattcaaaag ccgtctgaaa atttaaaagt
//
LOCUS       DAXISH010000016        30678 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.016, whole genome shotgun sequence.
ACCESSION   DAXISH010000016 DAXISH010000000
VERSION     DAXISH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 30678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30678
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.016"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(34..267)
                     /locus_tag="ACFOV4_000768"
     CDS             complement(34..267)
                     /locus_tag="ACFOV4_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618817.1"
                     /translation="MPSESPSDGICFPKRIILPQAYANPFYRIGNSKKNPFHSHAGKP
                     VFDFGYFWLFRVIYESSFPRRRESRPFGFGFFG"
     gene            complement(297..3062)
                     /gene="tdfH"
                     /locus_tag="ACFOV4_000769"
     CDS             complement(297..3062)
                     /gene="tdfH"
                     /locus_tag="ACFOV4_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent zinc piracy receptor TdfH"
                     /protein_id="HFC7618818.1"
                     /translation="MKSSFRLKPICFYLMGVMLYHHSYAEDAGRAGSEAQIQVLEDVH
                     VKAKRVPKDKKVFTDARAVSTRQDIFKSSENLDNIVRSIPGAFTQQDKSSGIVSLNIR
                     GDSGFGRVNTMVDGITQTFYSTSTDAGRAGGSSQFGASVDSNFIAGLDVVKGSFSGSA
                     GINSLAGSANLRTLGVDDVVQGNNTYGLLLKGLTGTNSTKGNAMAAIGARKWLESGAS
                     VGVLYGHSRRSVAQNYRVGGGGQHIGNFGAEYLERRKQRYFVQEGALKFNSDSGKWER
                     DLQRQQWKYNPYKNYNNQELQKYIEDHDKSWRENLAPQYDITPIDPSSLKQQSAGNLF
                     KLEYDGVFNKYTAQFRDLNTKIGSRKIINRNYQFNYGLSLNPYTNLNLTAAYNSGRQK
                     YPKGSKFTGWGLLKDFETYNNAKILDLNNTATFRLPRETELQTTLGFNYFHNEYGKNR
                     FPEELGLFFDGPDQDNGLYSYLGRFKGDKGLLPQKSTIVQPAGSQYFNTFYFDAALKK
                     DIYRLNYSTNTVGYRFGGEYTGYYSSEGEFKRAFGENSPTYKKHCNPSCGLYEPVLKK
                     YGKKRANNHSVSISADFGDYFMPFASYSRTHRMPNIQEMYFSQIGDSGVHTALKPERA
                     NTWQFGFNTYKKGLLKQDDTLGLKLVGYRSRIDNYIHNVYGKWWDLNGNIPSWVSSTG
                     LAYTIQHRNFKDKVHKHGFELELNYDYGRFFTNLSYAYQKSTQPTNFSDASESPNNAS
                     KEDQLKQGYGLSRVSALPRDYGRLEVGTRWLGNKLTLGGAMRYFGKSIRATAEERYID
                     GTNGGNTRDVRQLGKRSIKQTETLARQPLIFDFYAAYEPKKNLIFRAEVKNLFDRRYI
                     DPLDAGNDAATQRYYSSFDPKDKDEEVTCNDDKTLCNGKYGGTSKSVLTNFARGRTFL
                     MTMSYKF"
     gene            complement(3871..4431)
                     /locus_tag="ACFOV4_000770"
     CDS             complement(3871..4431)
                     /locus_tag="ACFOV4_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA large subunit pseudouridine synthase E"
                     /protein_id="HFC7618819.1"
                     /translation="MKNLIAFNKPYGVICQFSPHEKHKSLKDFINLPGFYPAGRLDTD
                     SEGLLLLTDDGRLQAQITDPKFKHPKTYWAQLEGVPDESRLESLRKGIDLGGFVTRPA
                     SIRILKHGEADSLWERIPPIRVRKTVPDFWIEITISEGKNRQVRRMTAKAGYPCLRLI
                     RVASGRLKLFDLDLKPGEWAYAPFKP"
     gene            4560..4751
                     /locus_tag="ACFOV4_000771"
     CDS             4560..4751
                     /locus_tag="ACFOV4_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618820.1"
                     /translation="MDFQFFVETIRRQEKKLKHGVYRLFEIYSWLEDGKATKARIRYF
                     VKIEVDKQILRRIHRGIAD"
     gene            complement(4947..5141)
                     /locus_tag="ACFOV4_000772"
     CDS             complement(4947..5141)
                     /locus_tag="ACFOV4_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HFC7618821.1"
                     /translation="MKHKLASWWKTIKLTANLMAGVPDYENYVAQQRKHNPNAPVMTK
                     LQFQDYCRKRRCGANGGRCC"
     gene            complement(5131..7212)
                     /locus_tag="ACFOV4_000773"
     CDS             complement(5131..7212)
                     /locus_tag="ACFOV4_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HFC7618822.1"
                     /translation="MKSLKTFLIWGIVVLVGLASFTTLALSRGEQVSAVWMVTAAISV
                     YCIAYRFYSLYIANRVMRLDPNRLTPAERHNDGLDYVPTHKGVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGTLWIIFGVVFAGAVQDMMVLFVSMRRDGKSLGDIVKQELGTVPG
                     VIASIGILMIMVIIMAVLALIVVKALVHSPWGTFTIAATMPIALFMGIYTRYIRPGKI
                     GEISIVGFILLMLAVIYGEDVAKSSIGHWFDLDGIQLTWAIMIYGFVASVLPVWLLLT
                     PRDYLSTFLKIGTIAALALGIVIVNPTLQMPAVTHFIDGSGPVFSGALFPFLFITIAC
                     GAVSGFHALISSGTTPKMLENETHVRMIGYGGMLMESFVAIMALAAAASLDPGVYFAM
                     NSPAALIGTDANTAAEVITTKLQFPVDAATLLHTAKEVGENTILSRAGGAPTLAVGMA
                     HIMSRLIPGEAMMAFWYHFALLFEALFILTAVDAGTRVARFMIQDLGSIFYKPFGNTD
                     SIPANLIATFFAVALWGYFLYTGVTDPLGGINSLWPLFGIANQMLAGVALIMCAVVLI
                     KMKRDRYVWVVLVPAVGVLFVTCYAGLQKLFHSDPRISFLAHAGKYSDALAKNEVLAP
                     AKDIGEMAQIIFNDKINAGLTILFLSVVVIVAAYGLRTALKARKVGWPTAKEIPAVYR
                     DGKQPEAQSEA"
     gene            7688..8068
                     /locus_tag="ACFOV4_000774"
     CDS             7688..8068
                     /locus_tag="ACFOV4_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MliC family protein"
                     /protein_id="HFC7618823.1"
                     /translation="MNIRFFALTVPVLSLAACAVPEAYDDGRRGYMPPVQNQAGPNDF
                     RAFSCENGLSVRVRRLDGGKIALRLDGRRAVLSSDVAASGERYTAEHGLFGNGTEWHQ
                     KGGEAFFGFTDAYGNSVETSCRAR"
     gene            complement(8201..8694)
                     /locus_tag="ACFOV4_000775"
                     /pseudo
     CDS             complement(8201..8694)
                     /locus_tag="ACFOV4_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713843.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="contact-dependent growth inhibition system
                     immunity protein"
     gene            9171..10604
                     /locus_tag="ACFOV4_000776"
     CDS             9171..10604
                     /locus_tag="ACFOV4_000776"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFC7618824.1"
                     /translation="MNEYSQLIKHPDISLSPISDSIGIGNPATGEILAYVRNTGSDKL
                     KNLIQKAAAAQKLWAAKTALERADILWRWYFLVKENKEALARLMTMEQGKSLTEARGE
                     IDYAASFVRWFAEEARRIDGDVLTSVKASQKLVVLKQPVGVTAAITPWNFPSAMIARK
                     AAPALAVGCAMIVKPASLTPLSAYALASLAYEAGIPQDLLPVVSGSASEIGHEFATNP
                     IIRKISFTGSTEVGAKIFADSAADIKKLSLELGGNAPFIVFDDADLDKAVEGALASKF
                     RNSGQTCVCTNRVYAQSAIYDEFCRKLSEKAAALKLGNGLEDGVNQGPLIEEKAVEKV
                     EQHIADALAKGASCLTGGKRSALGGTFFEPTVLSGVTAQMAVAREETFGPLCPVFRFE
                     TEAEVIEAANNTEYGLAAYLFTADTARQWRVGEALEYGMVGINTGLISNEAAPFGGVK
                     RSGLGREGSKYGADEYLELKYLCMDVG"
     gene            10713..11501
                     /locus_tag="ACFOV4_000777"
     CDS             10713..11501
                     /locus_tag="ACFOV4_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimb protein"
                     /protein_id="HFC7618825.1"
                     /translation="MMENGKTVPRWRFALKSAGWHLLISLSVAGLAALLVFKVWYPYP
                     YAELTGGLSLYQLVVAVDIVCGPLLTLILASPKKKTKARMVDFSMVGIIQLAALVYGL
                     HSVSLARPVVEAFEQDRMTIVTAAEVVVEDLHKAPEGLQSLSWFGIRRIALKEPEDAD
                     EKNKTLDLSLKGIEPSMRPDQWLPYSDKEAEEIRKHLKPLKVLADARKTTVADILKQA
                     GLAEGEELYYLPFTSSRQKEWIVITDKEGNTKGYAPIDGFIITP"
     gene            11869..13425
                     /locus_tag="ACFOV4_000778"
     CDS             11869..13425
                     /locus_tag="ACFOV4_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter associated domain-containing
                     protein"
                     /protein_id="HFC7618826.1"
                     /translation="MDFSWLAEPHTWIGFATLLVLEVVLGIDNLVFVAILANKVQPAR
                     RDRARIIGLGLAVVIRIIMLAFMAHIITLTEPLFQIGGLAVSGKDMIMLAGGIFLLYK
                     ATTELHERLEGHNRFTVADNQKKHAPFWGVVAQILILDAVFSIDSVITAVAMVDHIVV
                     AMGAVVVAMAVMISASKLLTEFVDRHPTVVMLCLGFLLMIGFSLIAEAFHFHIPKGYL
                     YAAIGFSILIELFNQISQRNSRKNDYIGSSWRKRTAENVLGMMGIRESVLADAGGESG
                     DDAHFEENEKSMIRSVLTLAERPIMGVMIPRRDIERLDISQSREEQCAQLQNTPYSRL
                     LVVGKAGVDEPLGYINKKDLLSQLLETGGLDIQTALRQPLVLPDSTTALGAIELFRQS
                     SADYALVVDEFGAVLGMVTMKDLLETIAGEFPEEFEREEEPAVQGNPDESLTVEGALE
                     YVELAPQLNLPQQEEDADFHTVAGLIMEELQTIPDVGDFADFHGWRFEVVEKEGQRIE
                     RVKITKLPEE"
     gene            13442..14188
                     /gene="surE"
                     /locus_tag="ACFOV4_000779"
     CDS             13442..14188
                     /gene="surE"
                     /locus_tag="ACFOV4_000779"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HFC7618827.1"
                     /translation="MNVLISNDDGYLSEGIAVLARVTAEFANVRVVAPERDRSGVSNS
                     LTLERPLQLKQAQNGFYYVNGTPTDCIHIGQSVFSDFQADFVFSGINRGANMGDDTLY
                     SGTVAAATEAYLMGIPAVAFSLNDASGRYWATAEKALWTLLAHFFKNPPQSPILWNIN
                     IPAVEPEDVRGIKIARLGRRHHGQNVIPARNPRGEQIYWIGPVGRVSDKEEGTDFGEC
                     GAGFITVTPLQIDLTAYPDMAETAVFWHAD"
     gene            14444..15691
                     /locus_tag="ACFOV4_000780"
     CDS             14444..15691
                     /locus_tag="ACFOV4_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HFC7618828.1"
                     /translation="MLKQTTLLAACASFAALLGGCATQQPAPVIAGNSGMQDAPSSAV
                     YNNPYGATPYSPAPAGDAPYVPPVQSAPVYTPPAYVPPSAPAVSGTYVPSYAPVDINA
                     ATHTIVRGDTVYNISKRYHISQDDFRAWNGMTDNTLSIGQIVKVKPAGYAAPKTAAVK
                     SRPAVPAAAQPPVQSAPVDINAATHTIVRGDTVYNISKRYHISQDDFRAWNGMTDNML
                     SIGQIVKVKPAGYAAPKTAAVESRPAVPAAVQTPVKPAAQPPVQSAPQPAAPAAENKA
                     VPAPAPQSPAASPSGTRSVGGIVWQRPTQGKVVADFGGNNKGVDIAGNAGQPVLAAAD
                     GKVVYAGSGLRGYGNLVIIQHNSSFLTAYGHNQKLLVGEGQQVKRGQQVALMGNTDAS
                     RTQLHFEVRQNGKPVNPNSYIAF"
     gene            complement(15898..16380)
                     /locus_tag="ACFOV4_000781"
     CDS             complement(15898..16380)
                     /locus_tag="ACFOV4_000781"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFC7618829.1"
                     /translation="MTQQRQLPSHELIMSELMMPDTANFSGNVHGGELLLLLDQVAYS
                     CASRYSGNYCVTLSVDKVLFKEPIHIGDLVTFYAAVNYTGRTSMEIGIRVEAQNIRTG
                     EIRHTNSCYFTMVAVKDGKPVPVPPLEILTDRQRCRYEKAKKRRDISLQASEDMSCGC
                     "
     gene            complement(16533..16694)
                     /locus_tag="ACFOV4_000782"
     CDS             complement(16533..16694)
                     /locus_tag="ACFOV4_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618830.1"
                     /translation="MSEQPEKHHTSPIEDERKNPVYRMGRAVAGFMLVVWAGVLALVF
                     FLVFRFWLS"
     gene            complement(16768..17229)
                     /gene="recX"
                     /locus_tag="ACFOV4_000783"
     CDS             complement(16768..17229)
                     /gene="recX"
                     /locus_tag="ACFOV4_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFC7618831.1"
                     /translation="MKPQKSLRARAMDILSRQEVSRIGLKRKLAPHAESEEELENVLN
                     EFAERNWQSDLRYAEAYIRSKSRKHGSLRLKQALAQQGIDEETSRNLLPDRSNEKQAA
                     IDVLRKKFKHPAADLKEKQKQARFLAYRGFDADTVQTALKHAWDENWEDGC"
     gene            complement(17286..17993)
                     /locus_tag="ACFOV4_000784"
     CDS             complement(17286..17993)
                     /locus_tag="ACFOV4_000784"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008967 - phosphoglycolate phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HFC7618832.1"
                     /translation="MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPA
                     KVVESYVGDGIGKLVHRVLSNDRDREADSELWEKGFVSYMKYYRDHLSVFTRPYPETE
                     AGLALLKSLGIPLAVITNKNEILAAELLKQLGLADYFSLILGGDSLPEKKPSPLPLRH
                     AAEVLGIDVANMVMVGDSRNDIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIG
                     SLPEIYENLQPQKNKEE"
     gene            18400..19665
                     /locus_tag="ACFOV4_000785"
     CDS             18400..19665
                     /locus_tag="ACFOV4_000785"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="HFC7618833.1"
                     /translation="MSEALAKETLNPFEIARKQVKTACDRLKTDPAVYEILKSPTRVL
                     EVNFPVKLDDDTVKTFTGYRSQHNNAVGPYKGGVRFHPGVNLDEVKALSIWMTIKCCV
                     AGIPYGGGKGGITLDPRDYSEAELERIARAYSEAISPLIGEKIDIPAPDVNTNGKIMS
                     WMVDAYENVVKHSAPGVFTGKPVEFGGSLARTEATGYGVNLAAVQALEKLGKDVKGAT
                     YAIQGFGNVGYHTGYYAHQSGAKIVAVSTVDVAIYNENGLDMEAIIKEFQTKGFITNE
                     AGYGKEISNAELLALEVDVLAPCALENQLTSENAGKVRATIVVEGANGPTTPEADVIL
                     RQNGVLVVPDILANCGGVVVSYFEWVQNLQGYYWEFDEVQEKETVVLRRAFRDIWNLA
                     QEYDVDLRTASYMMSIRRVEKAMKLRGWY"
     gene            complement(19723..20529)
                     /locus_tag="ACFOV4_000786"
     CDS             complement(19723..20529)
                     /locus_tag="ACFOV4_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /protein_id="HFC7618834.1"
                     /translation="MKKTLTLLAVSALFATSAHAHRVWVETAHTHGGEYLKADLGYGE
                     FPELEPIAKDRLHIFSKPMQLVTEKGKENMIQRGTYNYQYRSNRPVKDGSYLVIAEYQ
                     PTFWSKNKAGWKQAGIKEMPDASYCEQTRMFGKNIVNVGHESADTAIITKPVGQNLEI
                     VPLDNPANIHVGERFKVRVLFRGEPLPNATVTATFDGFDTSDRSKTHKTEAQAFSDST
                     DDKGEVDIIPLRQGFWKANVEHKADFPDQSVCQKQANYSTLTFQIGHSHH"
     gene            20874..21083
                     /locus_tag="ACFOV4_000787"
     CDS             20874..21083
                     /locus_tag="ACFOV4_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase family protein"
                     /protein_id="HFC7618835.1"
                     /translation="MPYVNIKVTGGKEAPTAAQKAELIGGVTELLARVLGKNPETTVV
                     VIDEVDTDNWGIGGKSVSERRKEGR"
     gene            21172..22386
                     /locus_tag="ACFOV4_000788"
     CDS             21172..22386
                     /locus_tag="ACFOV4_000788"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFC7618836.1"
                     /translation="MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPA
                     PFGFEAPDEILVDVIRNLPTSQGYCDSKGLYSARKAIVHYYQTKGLRDITVDDVYIGN
                     GVSELITMSMQALLNDGDEILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLAD
                     MEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGA
                     VHHHIAALAPDLLTVTFNGLSKAYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRL
                     CANTPMQHAIQTALGGYQSINEFILPGGRLLEQRNRAWELVNQIPGVSCVKPMGAMYM
                     FPKIDTEMYRIHDDMKFVYDLLVREKVLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAM
                     GRLARFLQTYRQ"
     gene            complement(22472..25051)
                     /gene="clpB"
                     /locus_tag="ACFOV4_000789"
     CDS             complement(22472..25051)
                     /gene="clpB"
                     /locus_tag="ACFOV4_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFC7618837.1"
                     /translation="MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNS
                     GAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGDILPSRELQAVLNLMDKAATKRG
                     DAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
                     LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIVNGEVPESLRNKRLLVLDLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIF
                     IDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYRQYIEKDAALERRFQ
                     KVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAID
                     LIDEAASRVKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEING
                     LQKEYADLDEIWKAEKAISDGAANIKKQIDEVKIKIEQAKRQGDLALASKLMYEDLEH
                     LEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGERDKLLKM
                     EEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAG
                     FLFDSEDHLIRIDMSEYMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDE
                     VEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTSNIGSQHIQQMGIQDYEAV
                     KEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTV
                     SDAALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEADGDRL
                     KFA"
     gene            25312..26322
                     /gene="trpS"
                     /locus_tag="ACFOV4_000790"
     CDS             25312..26322
                     /gene="trpS"
                     /locus_tag="ACFOV4_000790"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFC7618838.1"
                     /translation="MSKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLA
                     DYHGIIKCHEPEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNWILTCITA
                     KGLMNRAHAYKAAVQANAENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQ
                     IQHVEMARDIAGRFNHRFRELFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWEND
                     KKTQKSVNKIITNMKEPGEPKQPDESPLFEIYKAFSTPSETVEFTKMLADGLAWGEAK
                     KLLAAKINAELAEPRERYNELTADPSQIEEILQAGAQKARKEARELLDKVRDAVGIRP
                     LK"
     gene            26328..26669
                     /locus_tag="ACFOV4_000791"
     CDS             26328..26669
                     /locus_tag="ACFOV4_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618839.1"
                     /translation="MPSEPLKGLPEQNVVRLTGKHPNDLEAVSGKCMETDDKGGPVGW
                     AENGVCHTLFAKLVGNIAEDGGKLTDYLISHSALQPYQAGKSGYAAVQNGRYVLEIDS
                     EGAFYFRRRHY"
     gene            26991..27314
                     /locus_tag="ACFOV4_000792"
     CDS             26991..27314
                     /locus_tag="ACFOV4_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618840.1"
                     /translation="MKKLLIAAMMAAALAACSQEAKQEVKEAVQAVESDVKDTAASAA
                     ESAASAVEEVKDQVKDAAADAKASAEEAVTEAKEAVTEAAKDTLNKAADATQEAADKM
                     KDAAK"
     gene            complement(27523..29031)
                     /gene="ppx"
                     /locus_tag="ACFOV4_000793"
     CDS             complement(27523..29031)
                     /gene="ppx"
                     /locus_tag="ACFOV4_000793"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004309 - exopolyphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006798 - polyphosphate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HFC7618841.1"
                     /translation="MTTTPANVLASVDLGSNSFRLQICENNNGQLKVIDSFKQMVRFA
                     AGLDEQKNLSAASQEQALDCLAKFGERLRGFRPEQVRAVATNTFRVAKNIADFLPKAE
                     AALGFPIEIIAGREEARLIYTGVIHTLPPGGGKMLVIDIGGGSTEFVIGSTLNPDITE
                     SLPLGCVTYSLRFFQNKITAKDFQAAISAARNEIQRISKNMRREGWDFAVGTSGSAKS
                     IRDVLAAEMPQEADITYKGMRALSERIIEAGSVKKAKFENLKPERIEVFAGGLAVMMA
                     AFEEMKLDRMTVTEAALRDGVFYDLIGRGLNEDMRGQTVAEFQHRYHVSLNQAKRTAE
                     TAQTFMDSLCHAKNVTVQELALWQQYLGRAAALHEIGLDIAHTGYHKHSAYILENADM
                     PGFSRKEQTILAQLVIGHRGDMKKMSGIIGTNEMLWYAVLSLRLAALFCRSRQDLSFP
                     KNMQLRTDTESCGFILRIDREWLERHPLIADALEYESVQWQKINMPFKVEVV"
     gene            complement(29147..29987)
                     /locus_tag="ACFOV4_000794"
                     /pseudo
     CDS             complement(29147..29987)
                     /locus_tag="ACFOV4_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714481.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein assembly modifier"
     gene            30350..>30678
                     /locus_tag="ACFOV4_000795"
     CDS             30350..>30678
                     /locus_tag="ACFOV4_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="opacity family porin"
                     /protein_id="HFC7618842.1"
                     /translation="MQADLAYAAERITHDYPQATGANNTSTVSDYFRNIRAHSIHPRV
                     SVGYDFGGWRIAADYASYRKWNDNKYSVNTKEVLRNNSTGTENWQELKTENQENGSFH
                     AASSLGLS"
BASE COUNT         7105 a         7596 c         8310 g         7667 t
ORIGIN      
        1 aaagtgggaa tctagaaatt taatgttgcg gcactaacca aaaaaaccga aaccgaacgg
       61 tctagattcc cgcctgcgcg ggaatgacga ctcataaatt acccgaaaca accaaaaata
      121 accgaaatca aaaaccggct tccctgcgtg ggaatgaaat ggatttttct ttgagttgcc
      181 gatgcgataa aacggattgg cataggcttg cggcaggatg atgcgtttgg ggaaacaaat
      241 gccgtctgaa gggctttcag acggcattgc ggttttctac aaaacgcggg ctgcctttaa
      301 aacttgtagc tcatcgtcat caaaaaggtg cgtccgcgtg caaaattggt caatacgctt
      361 ttgcttgtgc cgccgtattt gccgttgcac aacgttttat catcattaca cgttacttct
      421 tcgtccttgt ctttcgggtc gaacgagctg taataacgct gcgttgccgc atcattgccc
      481 gcatcgagcg gatcgatata acgcctgtcg aacagatttt tgacttcggc gcggaaaata
      541 aggtttttct tcggctcgta agcggcgtaa aaatcaaaaa tcaaaggctg gcgggcaagg
      601 gtttcggttt gtttgatgga acgcttgccc agttgccgga catcgcgggt atttcccccg
      661 ttggtgccgt cgatatagcg ttcttcagcc gtcgcgcgga tgctcttgcc gaaatagcgc
      721 atcgcgccgc ccaaagtcag tttgttgccc aaccagcgcg taccgacttc caaacgtccg
      781 taatctcgcg gcagggcgga aaccctgctc aacccataac cttgtttgag ttggtcttct
      841 ttggacgcat tgttgggcga ttcgctcgca tcgctgaagt tggtcggttg cgtgcttttt
      901 tgataggcgt aagaaaggtt ggtgaaaaaa cgcccataat cgtaattcag ctccaactca
      961 aaaccgtgtt tgtgcacttt gtctttgaaa ttgcggtgtt ggatggtgta ggcaagcccg
     1021 gtgctgctga cccagctcgg aatattcccg ttcaaatccc accatttccc gtaaacgttg
     1081 tggatgtagt tgtcgatgcg gctgcggtag ccgaccagtt ttaatcctaa tgtatcatct
     1141 tgttttaaca gtcctttttt ataggtattg aagccaaatt gccaagtgtt tgcgcgctct
     1201 ggttttaagg cggtgtgaac gccggagtcg ccgatttggg aaaaatacat ttcttggatg
     1261 ttgggcatac ggtgtgtgcg cgaatagctg gcgaacggca tgaaataatc gccgaagtcc
     1321 gcactaatgc tgaccgaatg gttgttggcg cgctttttgc cgtatttttt caatacgggt
     1381 tcataaagcc cgcagctcgg gttgcaatgt ttcttgtatg tcggcgagtt ttctccgaat
     1441 gcccgcttaa attcgccttc cgagctgtaa tagcccgtat attcgccgcc gaaacggtag
     1501 ccgacggtat tggtgctgta gtttaagcgg taaatgtctt ttttgagcgc ggcatcgaag
     1561 tagaacgtgt tgaaatattg gctgccggcc ggttggacaa tggttgattt ttggggcagc
     1621 agccctttat cgcccttaaa ccgccccaaa taggaataaa gcccgttgtc ctgatcagga
     1681 ccgtcgaaaa acagccccaa ttcttcagga aagcggtttt tgccgtattc gttgtggaaa
     1741 taattgaagc ccaacgtggt ttgcaactcg gtttcgcggg gcagccggaa ggtggcggtg
     1801 ttgttgaggt cgaggatttt cgcgttgttg taggtttcaa aatcctttaa aagtccccag
     1861 cctgtaaact tcgacccttt cggatatttc tgcctgcccg aattgtaggc tgcggtcaga
     1921 ttgaggttgg tatacgggtt caaagacaaa ccgtaattga attgataatt gcggttgatg
     1981 attttgcggc tgccgatttt ggtgtttaaa tcgcgaaatt gcgccgtgta tttattgaat
     2041 acgccgtcgt attccaattt aaacagattg cctgccgact gctgcttcag gctggacgga
     2101 tcgatggggg tgatgtcgta ttgcggcgcc aggttttccc gccagctttt atcatggtct
     2161 tcgatgtatt tttgtagttc ttggttgttg taatttttat acggattgta tttccactgt
     2221 tgcctttgta aatcccgctc ccattttccg ctgtcggaat tgaatttcaa agcaccctct
     2281 tgtacaaaat atcgctgctt gcgccgttcc aaatattccg cgccaaaatt tccgatgtgc
     2341 tgcccgccgc cgcccacgcg gtaattttgc gccacgctgc gcctgctgtg cccgtaaagc
     2401 acaccgacag atgctccgct ttccagccat ttgcgcgcac ctatcgccgc catcgcatta
     2461 cctttggttg aattggtgcc ggtcagacct tttagcagca ggccgtaggt attattgccc
     2521 tgaacgacgt catccacgcc taaagtccgc agattcgccg aaccggcaag gctgttgatg
     2581 cctgccgagc cgctgaagct gcctttgacg acatccagtc cggcaataaa attgctgtcg
     2641 acagatgcac cgaattgaga tgaaccgcct gccctgcccg catcggtaga agtcgaataa
     2701 aaggtctgcg tgatgccgtc caccatcgta ttgacccgcc cgaacccgct gtcgccgcga
     2761 atattcaaag acacaatgcc cgagctttta tcttgctgtg taaacgcacc ggggatgctg
     2821 cgtacgatgt tgtcgaggtt ttcgctggat ttgaatatat cctgacgggt cgatacggca
     2881 cgcgcatcgg taaacacttt tttgtctttc ggtacgcgct tcgccttgac gtgcacatct
     2941 tccaaaacct gtatctgcgc ctcgctgccc gcgcgccctg catcttcggc ataactatga
     3001 tgatatagca taacacccat aagataaaaa caaatcggct tcaaccggaa agaagatttc
     3061 atattttcct caacaataaa cagtcagaca attaagaaat atattagcat ttttttaggc
     3121 ggcataaaca ttaaaaagtg taaattcgat ataccgtctg aagatttcaa ttggatgaga
     3181 cctttgcaaa aatagtctgt taacgaaatt tgacgcataa aaatgcgcca aaaaattttc
     3241 aattgcctaa aaccttccta atattgagca aaaagtagga aaaatcagaa aagttttgca
     3301 ttttgaaaat gagattgggc ataaaatttt agtaacctat gttattgcaa aggtctctgg
     3361 atatttatag tggattaaca aaaaccggta cggcgttgtc tcgccttagc tcaaagagaa
     3421 cgattctctg ttgctacggt tactgtcagg tttcggttat gttggaattt cgggaaactt
     3481 atgaatcgtc attcccgcgc aggcgggaat ccggtccgtt cggtacggaa acttatcgga
     3541 taaaacggtt tcttcagatt ttacgttctg gattcccact ttcgcgggaa tgacgaaaag
     3601 tggtgggaat gacggttcgg gcattcctta aatcacccgt gtatcgctgt aaatcttaga
     3661 gatggcggaa tatagcggat taacaaaaac cagtacggcg ttgtctcgcc ttggctcaaa
     3721 gagaacgatt ctctaaggtg ctgaagcacc aagtgaatcg gtttcgtact atttgtactg
     3781 tctgcggctt cgtcgccttg tcctgatttt tgttaatcca ctataaaatt ccggattccc
     3841 acttttgtgg aaatgatgag ataaacgtga ttatggttta aacggggcgt atgcccattc
     3901 cccgggtttt aaatccaaat caaacagttt cagcctgccg cttgccactc tgatcagacg
     3961 caggcaggga tagcccgcct tggcggtcat tcgcctgact tggcggtttt tgccctcaga
     4021 aatggtaatt tcaatccaaa aatcgggaac ggttttgcgg acgcgtatcg gcgggatgcg
     4081 ctcccataac gaatctgctt ctccgtgttt caagatgcgg atgcttgccg gacgggtaac
     4141 gaaaccgcct aagtctatcc cttttcttag gctttccaat cggctttcgt cgggtacgcc
     4201 ctccagttgc gcccagtagg ttttagggtg tttgaatttg gggtcggtaa tttgtgcctg
     4261 aagcctgccg tcgtcggtca gcagcagcag cccctcgctg tcggtgtcga gccgtccggc
     4321 ggggtagaag ccgggaagat tgataaagtc tttgaggctt ttgtgttttt cgtgcggtga
     4381 aaattggcag ataacgccat agggtttgtt gaaggcgatg aggtttttca taggttttgg
     4441 gtttgggttg aaatgggcgg cggtatcggg aaaatttgtt tattgcgaag ggacatccga
     4501 taaatggtgc ttccaaagtg aaaaggtttg aatgcagatt aaattttaag gtgcatgaaa
     4561 tggattttca attctttgtc gaaacaatcc gccgacagga aaagaaactg aagcatggcg
     4621 tgtaccggct gtttgagatt tacagttggt tggaagatgg aaaagcaaca aaggcgcgta
     4681 tccggtattt tgtcaaaatt gaggtcgata aacagatatt gcgaaggatt catcgtggta
     4741 tagcggatta acaaaaaccg gtacgtcgtt gcctcgcctt agctcaaaga gaacgattct
     4801 ctaaggtgct gaagcaccaa gtgaatcggt ttcgtactat ttgtactgtc tgtggcttcg
     4861 tcgccttgtc ctgatttttg ttaatccact atattataaa aattccgtct gaagcggcgt
     4921 tcagacggca tttgtttcag gcggggctaa cagcagcgtc cgccgtttgc gccgcagcgg
     4981 cgtttgcggc aatagtcttg aaactgcagc ttggtcatca cgggggcgtt gggattatgt
     5041 ttgcgctgct gtgcaacgta gttttcataa tcaggcacgc ctgccatcaa gtttgccgtc
     5101 agcttgatgg ttttccacca agacgcgagc ttatgcttca ctttgtgcct ccggctgctt
     5161 gccgtcgcgg tacaccgccg ggatttcttt ggcggtcggc cagccgactt tgcgtgcttt
     5221 gagggcggta cgcaaaccgt acgcggcgac aatcacgaca accgacaaga agaggatggt
     5281 cagaccggca ttaatcttgt cgttgaagat gatttgcgcc atttcgccga tgtctttggc
     5341 aggcgcaagg acttcgtttt tagccaatgc gtcgctgtat ttgccggcgt gggcaaggaa
     5401 gctgatgcgc gggtcgctgt ggaacagttt ttgcaggccg gcgtagcagg ttacgaacag
     5461 tacgccgacg gcgggaacga gtaccaccca aacataacgg tcgcgtttca tcttaatcag
     5521 caccacggcg cacataatca aggccacgcc tgccagcatt tggttggcga tgccgaacaa
     5581 aggccagagc gagttgatgc cgcccagcgg gtcggttacg ccggtgtaga ggaagtagcc
     5641 ccacaatgcc acggcgaaga aggtcgcaat caggttggcg gggatggagt cggtgttgcc
     5701 gaaaggtttg tagaagatgc tgcccaagtc ttgaatcata aaacgtgcga cgcgcgtacc
     5761 ggcatcgacg gcggtcagga tgaacaaggc ttcaaacaat agggcgaagt gataccagaa
     5821 cgccatcatc gcctcgcccg gaatcaggcg gctcataatg tgcgccatac cgactgcgag
     5881 ggttggcgca ccgcctgcac gggaaaggat ggtgttttcg cccacttcct tagcggtatg
     5941 caacagggtt gccgcatcga cagggaattg cagcttggtg gtaatcactt cggcggcggt
     6001 gttggcatcc gtaccgatca gggcggcagg gctgttcatg gcgaagtaca cgccgggatc
     6061 aagcgatgcg gcggcggcaa gcgccataat ggctacgaaa ctttccatca acataccgcc
     6121 gtaaccaatc atacggacgt gggtttcgtt ttccagcatt ttcggcgtgg tgccggagga
     6181 aatcagcgcg tggaagcccg aaaccgcacc gcaggcgatg gtgatgaaga ggaacgggaa
     6241 caatgcgcct gagaataccg gacccgaacc gtcgataaag tgggttacgg caggcatttg
     6301 caaagtggga ttgacgatga cgatgcccaa agccaaggcc gcaatcgtac cgattttcag
     6361 gaaggtggag agatagtcgc gcggagtgag cagcaaccat acgggcaata cggaggcgac
     6421 aaagccgtaa atcataatcg cccaagtgag ctggatgccg tcaaggtcga accaatgtcc
     6481 gatggaactt ttcgccacat cttcgccgta aattaccgcc agcatcagca aaataaagcc
     6541 gacgatggaa atctcgccga ttttgcccgg acggatatag cgcgtgtaaa tacccataaa
     6601 cagggcaatc ggcatagtgg cggcgatggt aaacgtaccc caagggctgt gaacaagtgc
     6661 ttttacgaca atcaacgcca acaccgccat aatgatgacc ataatcatca aaataccgat
     6721 ggaggcaatc acgccgggga cagtgccgag ttcctgtttc acaatatcgc ccaaagactt
     6781 accgtcacgg cgcatagaaa caaacagtac catcatatcc tgtaccgcgc cggcaaaaac
     6841 cacgccgaag ataatccaca aagtaccggg caggtaaccc atttgcgcag ccagtacagg
     6901 gccgaccaaa gggcccgcgc cggcaatcgc ggcaaagtgg tgtccgaaca atacgccctt
     6961 gtgcgtcgga acgtagtcca agccgtcgtt gtggcgttct gccggagtca ggcggttagg
     7021 atcgagccgc attacgcggt tggcgatgta gaggctgtaa aaacggtagg cgatgcagta
     7081 aacggatatg gcggcggtga ccatccatac cgcgctgacc tgttcgcctc ggctgagagc
     7141 cagagtggta aaggatgcta agccgaccag taccactatg ccccaaatga ggaaggtttt
     7201 gagtgatttc atcgaataaa tccttatctc acactgtcgg aatatgcctg aacggcggga
     7261 aacggatgac cgcctgccgg cacgggcaca aaccggagtc tgaatgattg acgaagtatg
     7321 aaacagtgcg cttgtcggga tttgtgcctt atgcccgcat caaacagtgc agggatgcgg
     7381 gcgcacaaaa cgttaaacgc cgaataggat tttaacgcaa attagcacac tgatagcggt
     7441 ttttacttgg aatttggaaa aaatttacat tccttcgggc ggacaggcgg gtttggatgg
     7501 catcgtcagg caaaaggcgg cgccggaaga cgggtaaaga aggggcgcgc aatccggatt
     7561 attgattcat cgcgggtaaa ttccggttat cgggcttgtg tgtttgcgcg tccgtttata
     7621 gtatggcgtt gccgcagctt ggaatcaggg cggttgtttc atatcttatt tttattgggg
     7681 agcttttatg aatatcaggt ttttcgcgct gaccgtaccg gttttgtctt tggcggcctg
     7741 tgccgtgccg gaggcgtatg atgacggcag acgcgggtat atgccgcctg ttcaaaacca
     7801 agccggcccg aacgattttc gggcgttttc atgcgagaac ggtttgtctg tgcgcgtccg
     7861 ccgtttggac ggtggcaaaa tcgcgttgcg gctggacggc aggcgtgccg tcctctcttc
     7921 cgacgttgcc gcatccggcg aacgctatac cgccgaacac ggtttgtttg gaaacggaac
     7981 cgagtggcac cagaaaggcg gcgaagcctt tttcggcttt accgatgcct acggcaattc
     8041 ggtcgaaact tcctgccgcg cccgttaaac ggggcagcct gtttgaaccg ccgtccggat
     8101 ttttcgggcg gttttttgtg tcggatttgt tttggctgtc ggctggtttc ggcggttttc
     8161 gggcgtggcg gattattttt cgtttcgttc cgggtttatc ctatcggcag cggctcaatg
     8221 ccaactttaa acctgctccg atttcttcag ggctgttatc caatgataaa atgacatcgt
     8281 ctgcatcaat ggcatcccac gcttccagct tgacatggcg gctcgggctg attttcaggc
     8341 agccgttgtg cagccaaata tccccgctca tcatgttttt aaatagggcg cgtctggttt
     8401 tatagcccaa gttcccgcat agtttggcaa cccaatcctc atagcgttgc cgaaattttt
     8461 cggtatcaaa aaaatcttgg tcttccgaac tgtcataaac gaaagtcctg ctgtttgcca
     8521 acgcttgcaa gaccgtcgtg cctaaagttt cattgtcggt atccaatggc aggatatggg
     8581 gggatatagg tggtctattg ccgttaaccc caaacctgaa catgtttgaa caatcagagc
     8641 ttcttcatta gcataaaaaa ctgcccaata attttgatcc tgtttaaaaa ttattatttg
     8701 atctccgtaa ttttgattgt atagtggatt aacaaaaatc aggacaaggc gacgaagccg
     8761 cagacagtac agatagtacg gaaccgattc acttggtgct tcagcacctt agagaatcgt
     8821 tctctttgag ctaaggcgag gcaacgctgt actggttttt gttaatccac tataatgttt
     8881 ggatttttgc catactctac cacacgttgc aactgcaatc tttgttcctt atatattatc
     8941 aaagggctgc attacttttc tttctaaatt accattgtat aaaaagtatt tttcttaaac
     9001 gacagggatt gcgcccgcgc catattcaga caccgcccgg atgttgcact gcccgatcgg
     9061 atgcttcaga cggcatcgga agggtttgca gttttggaat atgaagatga taatgtccgc
     9121 gagattgacg gcatttgaaa gcggttattc cgcataccgg aggatacgaa atgaacgaat
     9181 attcccaatt aatcaagcat cccgatattt ccctttcccc gatttcagac agcatcggga
     9241 tcggcaatcc ggcgacgggt gaaattttgg cgtatgtccg caacacgggt tcggacaaac
     9301 tgaaaaacct gattcaaaag gcggcggcag cgcaaaaatt atgggcggcg aaaactgctt
     9361 tggaacgcgc cgacatattg tggcgttggt attttttagt taaagaaaac aaagaagcac
     9421 tggcgcgcct gatgacgatg gagcagggca aaagcctgac cgaggcgcgc ggcgagattg
     9481 attatgcggc ttcgtttgtg cgctggtttg cggaagaggc gcggcggatt gacggcgatg
     9541 tgttaacgag tgtaaaagcg tcgcaaaaac tggttgtgtt gaaacagcct gtcggcgtta
     9601 ccgccgcgat tacgccgtgg aacttcccat ctgcgatgat tgcgcgcaag gccgcgcctg
     9661 ctttggcggt gggttgcgcg atgatcgtca aacccgcatc gctcacgcct ttgagtgcgt
     9721 atgccttggc ttcgttggct tacgaagcgg gcataccgca ggatttgttg cctgttgtca
     9781 gcggcagtgc ttcggaaatc ggccatgaat ttgctacgaa cccgattatc cgcaaaatca
     9841 gcttcaccgg ctcgaccgaa gtcggcgcaa aaatttttgc cgacagcgcg gcggacatta
     9901 aaaaactcag tttggagctg ggcggcaacg cgccgtttat cgtgtttgac gatgccgatt
     9961 tggacaaagc cgtcgaaggc gcgctcgcca gcaagttccg taacagcggt cagacctgcg
    10021 tctgcaccaa ccgcgtttac gctcaatccg ccatttacga cgaattttgc cgcaaattga
    10081 gtgaaaaagc agccgcgctc aaattgggca acggcttgga ggatggtgtg aaccaagggc
    10141 cgctgattga ggaaaaagcg gtggagaaag tcgagcagca catcgccgac gcgcttgcta
    10201 aaggtgcaag ctgcctgacc ggcggcaaac gcagcgcgtt gggcggaacg tttttcgaac
    10261 cgactgtttt aagcggcgta acggcgcaaa tggcggtggc acgcgaagaa accttcgggc
    10321 cgttgtgtcc ggtattccgt tttgaaaccg aagccgaggt catcgaggct gcgaacaata
    10381 cggaatacgg tttggcagct taccttttca ccgccgacac cgcccgccaa tggcgcgtcg
    10441 gcgaagcctt ggaatacggt atggtcggca tcaatacggg cttaatcagc aatgaagcgg
    10501 caccgttcgg cggcgtgaaa cgtagcggtt tgggacgtga aggcagcaaa tacggtgcgg
    10561 acgaatatct agaattgaaa tatctgtgta tggatgtcgg gtgacggatg ccgtctgaac
    10621 ggcaggattt cagacggcgc cgcattttaa gcagtctcta tctgttgtac aatgcgccct
    10681 gtttttacgg ttatttttga tttgaacaag atatgatgga aaacggaaaa acagtcccga
    10741 gatggcgttt tgccttgaaa agtgcgggct ggcacctctt aatcagcctg tcggttgcag
    10801 ggctggcggc attgctggtt tttaaggttt ggtatcctta tccttatgcc gagctgacgg
    10861 gagggctgtc gctttatcag ctggtggtgg ctgtcgatat tgtatgtggt ccgctgctga
    10921 ctttaatttt ggcaagcccg aagaaaaaga caaaggcacg catggtcgat ttttccatgg
    10981 tcggcatcat ccagctggcg gctttggtgt acggtctgca cagcgtttcg ctggcgcgtc
    11041 ctgtggtgga agcgtttgaa caggatcgta tgaccattgt tacggcggcg gaagtcgtgg
    11101 tcgaagattt gcacaaagcc cccgaagggc tgcaaagcct gtcgtggttc ggcatccgcc
    11161 gcattgcatt gaaagaacct gaggatgcgg atgagaagaa caagacgctg gatttgtccc
    11221 tgaaaggtat cgagccgagt atgcgtcccg accagtggct gccgtattcc gacaaggaag
    11281 cagaagaaat ccgcaaacat ctgaaaccgc tgaaagtctt ggcggatgcg agaaaaacga
    11341 cggttgcgga cattctgaaa caggcaggtc tcgccgaagg ggaggagctg tattacctgc
    11401 cgtttaccag cagcaggcag aaagagtgga tagtcattac cgataaagag ggcaacacca
    11461 aaggctacgc gccgatagac ggcttcatca tcacccctta agcgttggga ctccgtccgc
    11521 actcgaacat ccgttcttcg cggcggtaga atcagactgt atttgagagg ggcgcaaccc
    11581 ctcaatcagg gcaacacata ggggaaggct ttatgtgccg tccgtgtgtt gaaacatttc
    11641 aaaataagct catgccgtcc gaacatcctt tcagacggta tggcattttg ccattgcccc
    11701 gataagctgt taaactattt aaattatttc gaccgaaggt acacgcacat gcaagacccc
    11761 gagcagagca gcaagcccgc ccgccgtttt ttgtgcgtac cgtctgttca ggcagcttga
    11821 gcgcttcagg ctgccttttc gcgtttgaac ttgaggaata cgaaaatcat ggatttcagt
    11881 tggttggcag aaccgcatac ctggataggt tttgccacgc ttttggtgtt ggaagtcgta
    11941 ttggggatag acaatcttgt ctttgtggcg attttggcaa acaaggtcca gcccgcacgg
    12001 cgcgaccgcg cacggattat cgggctgggg ctggcagtcg tcatccgcat cattatgctt
    12061 gcttttatgg cgcacatcat cacgctgacc gagccgctgt tccaaatcgg cggcctcgcc
    12121 gtttccggca aggacatgat tatgctcgcg ggcggtattt tcctgcttta caaagccacc
    12181 accgaactgc atgaacgcct cgaagggcac aaccgtttta ccgttgccga caaccaaaaa
    12241 aaacacgcgc cgttttgggg cgtggtcgcg caaatcctga tactggatgc cgtgttttcc
    12301 atcgattcgg tcattactgc ggtggcgatg gtcgatcata tcgtcgtggc gatgggtgcg
    12361 gtcgtcgtcg cgatggctgt aatgatttct gccagcaaac tcttgaccga atttgtcgac
    12421 agacacccta ccgtcgtgat gctctgcctt ggttttttgt tgatgatcgg tttcagcctg
    12481 attgccgaag ccttccattt ccacattccc aaaggctacc tctacgccgc catcggcttc
    12541 tcgattttaa tcgaattgtt taaccagatt tcgcagcgca acagccgcaa aaacgactac
    12601 atcggcagct cgtggcgcaa gcgcaccgcc gaaaacgtct tgggtatgat gggtatacgc
    12661 gaaagcgtgc ttgccgacgc gggcggcgaa tccggggacg acgcgcattt tgaagaaaac
    12721 gaaaaatcga tgatacgcag cgtgctgacg cttgccgaac gcccgattat gggggtgatg
    12781 atcccacgcc gcgacatcga acggctggac atttcccaaa gccgcgaaga acagtgtgcc
    12841 caactgcaaa acacgcctta cagccgcctg ctcgttgtcg gtaaggcggg cgtggacgaa
    12901 cctttgggct acatcaacaa aaaagacctg ctgtcccaac tgctggaaac aggcggtctc
    12961 gacattcaga cggcattgcg ccagccactc gtcctgcccg acagcaccac cgcgctgggc
    13021 gcaatcgaac tcttccgcca aagcagcgcg gattatgctt tggtggtgga cgagttcggc
    13081 gcggtattgg gcatggtaac catgaaagac ctgctcgaaa ccatcgcagg cgagttcccc
    13141 gaagaatttg agcgcgaaga agaaccagcc gttcagggga atcccgatga aagcctgacg
    13201 gtggaaggcg cgttggaata tgtggaactc gcaccgcaac tcaacctgcc gcagcaggag
    13261 gaagatgccg atttccatac ggttgccggg ctgattatgg aagaattgca aaccatcccc
    13321 gatgtcggcg attttgccga tttccacggc tggcggtttg aagtggtcga aaaagaaggg
    13381 cagcgcatcg agcgggtcaa aatcaccaaa ttgcccgaag aataagcatt caggatagaa
    13441 aatgaacgtt ttgatttcca acgacgacgg ctacctctcc gaaggtattg ccgttttggc
    13501 gcgcgttacg gcggaatttg ccaacgtcag ggtggttgcg cccgaacgcg acaggagcgg
    13561 ggtcagcaat tcgctgacgc tggaacgccc tttgcagttg aaacaggcgc aaaacgggtt
    13621 ctactatgtc aacggcacgc cgaccgactg tatccacatc gggcagtctg tattttcgga
    13681 ttttcaggcc gattttgtct tttcgggcat caaccggggc gcgaatatgg gggacgacac
    13741 gctttattcg gggacggttg cggcggcaac cgaagcctac cttatgggca tacccgctgt
    13801 ggcgttttcc ttaaacgacg cttccggacg ctattgggca accgcagaaa aggcactgtg
    13861 gacattgttg gcgcattttt tcaaaaaccc cccgcagtcc cctattttgt ggaacatcaa
    13921 tatccccgcc gtcgagccgg aagatgtgcg gggcattaaa atcgcccgtt tgggcaggag
    13981 gcatcacggt cagaacgtca tccccgcgcg caatccgcgc ggcgaacaga tttattggat
    14041 aggcccggta ggcagggttt ccgacaaaga agagggaacg gatttcggtg aatgcggcgc
    14101 aggtttcatt accgtaacgc cgctgcaaat cgacctgacc gcctatccgg acatggcgga
    14161 aacagcggtg ttctggcatg cggactgacc gtttcatcaa atatagtgga ttaacaaaaa
    14221 ccagtacggc gttgcctcgc cttagctcaa agagaacgat tctctaaggt gctgaagcac
    14281 caagtgaatc ggttccgtac tatttgtact gtctgcggct tcgtcgcctt gtcctgattt
    14341 ttgttaatcc actataccgt cgggctttgc gcttgagaag aacgcgcatt tttattatga
    14401 tataccgcat tcaggctata tatcggaaca tgaaggttat cttatgttga aacaaacgac
    14461 acttttggcg gcttgcgcct cctttgccgc actgttgggc ggttgtgcta cccagcagcc
    14521 tgcccccgtc attgcaggca attcaggtat gcaggacgcg ccgtcttcgg cagtttacaa
    14581 caacccctat ggagcaacgc cgtacagccc ggctcctgcc ggcgatgcgc cttatgtgcc
    14641 gccggtgcaa agcgcgccgg tttatacgcc tcctgcttat gttccgccgt ctgcacctgc
    14701 cgtttcgggt acatacgttc cttcttacgc acccgtcgac atcaacgcgg cgacgcatac
    14761 tattgtgcgc ggcgacacgg tgtacaacat ttccaaacgc taccatatct ctcaagacga
    14821 ttttcgtgcg tggaacggca tgaccgacaa tacgttgagc atcggtcaga ttgttaaagt
    14881 caaaccggca ggatatgccg caccgaaaac cgcagccgta aaaagcaggc ccgccgtacc
    14941 ggctgccgcg caaccgcccg tacagtccgc acccgtcgac attaacgcgg cgacgcatac
    15001 tattgtgcgc ggcgacacgg tgtacaacat ttccaaacgc taccatatct ctcaagacga
    15061 tttccgtgcg tggaacggca tgaccgacaa tatgttgagc atcggtcaga ttgttaaagt
    15121 caaaccggca ggatatgccg caccgaaaac cgcagccgta gaaagcaggc ccgccgtacc
    15181 ggctgccgtg caaacccctg tgaaacccgc cgcgcaaccg cctgtgcagt ccgcgccgca
    15241 acctgccgcg cccgctgcgg aaaataaagc ggttcccgcg cccgccccgc aatctcctgc
    15301 cgcttcgcct tccggaacgc gttcggtcgg cggcattgtt tggcagcgtc cgacgcaagg
    15361 taaagtggtt gccgatttcg gcggcaacaa caagggtgtc gatattgccg gtaatgcggg
    15421 acagcccgtt ttggcggcgg ctgacggcaa agtggtttat gcaggttccg gtttgagggg
    15481 atacggcaat ctggtcatca tccagcataa ttcttccttc ctgaccgcat acgggcacaa
    15541 ccaaaaattg ctggtcggcg aaggccagca ggtcaaacgc gggcagcagg tcgctttgat
    15601 gggcaatacc gacgcttcca gaacgcagct tcatttcgag gtgcggcaaa acggcaaacc
    15661 ggttaacccg aacagctata tcgcgttctg actttctgcc tgaaatcaag ttggaaatgc
    15721 cgtctgaaag gttttcagac ggcatttttg tttttggcgg ctgtgttttc aaatcattcg
    15781 gaagggacgg ggcatataaa tttgtttgac tgtgtttggg tatttgcttg atttcatccg
    15841 tttgcagtag aaacggatgg cgcgatgtgc ctgtctttca gacggcatag tccgccgtca
    15901 gcagccgcag gacatgtctt cagaggcttg caggctgatg tctctgcgtt ttttggcttt
    15961 ttcgtagcgg cagcgttggc ggtcggtcag gatttccagc ggagggacag ggacgggttt
    16021 gccgtctttg accgcaacca tcgtgaagta gcagctgttg gtgtggcgga tttcgccggt
    16081 gcggatgttt tgtgcttcga cacggatgcc gatttccatc gaggtgcgtc ccgtgtagtt
    16141 gacagcggcg taaaaggtaa ccaaatcgcc gatgtggatg ggttctttaa acaggacttt
    16201 gtcaaccgac agggtaacgc aataattgcc gctgtaacgg ctggcgcagg aataggcaac
    16261 ctggtcgagc aggagcagga gttcgccgcc gtgtacgttg ccgctgaaat tggcggtgtc
    16321 cggcatcatc agttcggaca taatgagttc gtgggaaggc agttggcgtt gttgtgtcat
    16381 agtgtacctg ttttaagaaa gggtattttg aaatgggtgt ggaaaaattt tagggaatgg
    16441 gaaagtggaa ttcaagctaa aaaaagctat gatgggatag cctgccgaaa tgggctgccg
    16501 atgccgtctg aaggtttcag acggcatttt gtttaggaaa gccaaaaacg gaagaccagg
    16561 aaaaacacga gtgccaatac gcccgcccaa acgacgagca tgaatccggc aacagcccgt
    16621 cccatacggt aaaccgggtt tttgcgttcg tcttcgatgg gggaggtgtg gtgtttttcg
    16681 ggttgttcgg acattttgtt ctcaatcgga aaagttggaa acgggcgtaa ggttatgttg
    16741 ccgtgcaaaa agattcaaga aggaaggtca gcagccgtct tcccaatttt cgtcccaagc
    16801 gtgtttcaat gccgtctgaa cggtatcggc atcgaatccg cgataggcga ggaaacgcgc
    16861 ctgtttttgt ttttctttaa ggtcggcggc ggggtgtttg aattttttac gcaacacgtc
    16921 tatggcggcc tgtttttcgt ttgagcggtc gggaagcagg ttgcggctgg tttcttcatc
    16981 tatgccctgt tgcgccaaag cctgtttcag cctcaatgaa ccgtgtttgc ggcttttgct
    17041 gcggatatag gcttcggcat agcgcaaatc cgactgccag ttgcgttcgg caaattcgtt
    17101 taacacgttt tccaactctt cttcgctttc ggcgtgcggt gcaagtttgc gtttcagacc
    17161 gatgcggctg acttcttggc gcgagaggat gtccatcgcg cgggcgcgta gggatttttg
    17221 cggtttcatg gcggcagttt cggcgtgcgg caggtttcag acggcatagc gtgccgtccg
    17281 aatgcctact cttctttatt tttctgcggt tgcaggtttt cgtaaatttc gggcagcgag
    17341 ccgataatcc agtcggggcg ggtcgcatcg tcttgcgaga gcagcgtcat atcgccgtaa
    17401 ccgaaggtaa cgccgacgct caggcagccg gcggctttgg cggcgatgat gtcgttgcgc
    17461 gagtcgccga ccataaccat gtttgcaaca tcgataccca aaacttcggc ggcgtgccgc
    17521 agcggcaggg ggctgggttt tttttcgggc aggctgtcgc cgccgagtat caggctgaag
    17581 tagtcggcaa gtccgagctg tttcaacagt tcggcggcaa ggatttcgtt tttattggta
    17641 atgactgcca gcgggatgcc caaagatttg agcaatgcca gcccggcttc ggtttcggga
    17701 taggggcggg tgaagacgct caaatggtcg cggtagtatt tcatatagga tacgaaacct
    17761 ttttcccaca gttcggaatc ggcttcgcgg tcgcggtcgt tggagaggac gcggtgaacc
    17821 agtttgccga tgccgtcgcc cacatagctt tcgaccactt tggcgggcag cggtttcata
    17881 ccgagttgtt ccaacatcgc ttctgcggcg gcggcaaggt cggggacgga atcgcacagt
    17941 gtgccgtcca aatcgaaggc gacggcttgg acgtgttcga tggctgcatt cataatctga
    18001 tttcctgtcg ggttgaaagg gtttatttta acatcgtttg cacagggctt ctaatgtata
    18061 gattgttaac aatcgcaaca ggttttgcag gcggtgtttt cggatttcgg ggcggaatcg
    18121 ggcaagggtt tgaaatcccg gcgatgttcc aattaaattt ttaaaaaata aaaggatgcc
    18181 tatatcttta tttaatttga catttatttt tcggatgcgc gcgctgcttt ttcaggcgga
    18241 gtccgggctg attccgtgcg gcttgaaaaa taaaatcata tatagattaa tcaaatcggg
    18301 cttatgccga ctacacgcta ttacattttg tcgggaaatt ggttatagta atgagcgaaa
    18361 tgcacgcccc tgaaaatctt tttgtgaaaa ggaagcaaaa tgtctgaagc ccttgcaaaa
    18421 gaaaccctca atccgtttga aatcgcgcgc aaacaggtca aaaccgcctg cgaccggctg
    18481 aaaaccgatc cggccgttta tgaaatcctg aagagtccga cccgcgtgtt ggaagtcaat
    18541 ttccccgtca aactcgacga cgacacggtc aaaaccttca cgggctaccg ttcgcaacac
    18601 aacaacgccg tcggccccta taaaggcggc gtgcgctttc atcctggtgt gaatctggac
    18661 gaagtcaaag ccctgtcgat ttggatgacc atcaaatgct gcgttgcggg tattccttat
    18721 ggcggcggca aaggcggcat taccttggat ccgcgcgatt attccgaggc ggaactggaa
    18781 cgcatcgccc gcgcttattc cgaagccatt tctccgctga ttggcgagaa aatcgatatt
    18841 cccgcacctg atgtgaacac caacggcaaa atcatgtctt ggatggttga tgcctatgaa
    18901 aacgtggtga aacattctgc accgggcgta tttaccggca aaccggttga gttcggcggc
    18961 tctttggcgc gtaccgaagc caccggttac ggcgtgaatc tcgctgccgt ccaagctttg
    19021 gaaaaactgg gcaaagacgt gaagggtgcc acttacgcca ttcaaggttt cggtaatgtc
    19081 ggctaccaca caggttatta cgcgcatcaa tccggtgcga aaatcgttgc cgtttctact
    19141 gttgacgttg ccatctacaa tgaaaatggc ttggatatgg aagcaatcat caaagaattc
    19201 caaaccaaag gtttcatcac caatgaagcc ggctacggta aagaaatcag caatgccgaa
    19261 cttttggctc tggaagtgga cgtacttgcc ccttgcgcac tggaaaacca actgacttct
    19321 gaaaatgccg gtaaagtccg cgcgacaatc gtggtcgaag gcgcaaatgg cccgactact
    19381 ccagaggcag acgttatcct gcgtcaaaac ggcgtattgg tcgtgcctga tattctggcg
    19441 aactgcggcg gcgtggtcgt ttcctatttc gagtgggtgc aaaacctgca aggctattat
    19501 tgggagtttg acgaagttca agagaaagaa accgtcgtcc tgcgccgagc gttccgcgat
    19561 atttggaact tggctcaaga atacgatgtc gatttgcgaa ccgcgtctta tatgatgagt
    19621 atccgccgtg ttgaaaaagc gatgaaactg cgcggttggt attgatgttt gaacaaaaaa
    19681 tgccgtctga agccttcaga cggcattttt gtgcgggcgg gattaatggt gcgaatggcc
    19741 gatttggaag gttaaagtcg agtagttcgc ctgtttttgg cacacgcttt gatcggggaa
    19801 gtcggctttg tgttcgacat tggctttcca gaagccttgg cgcaagggga tgatgtccac
    19861 ttcgcctttg tcgtctgtgc tgtcggagaa agcctgtgct tcggttttgt gcgttttgct
    19921 gcggtcgctg gtgtcgaagc cgtcaaaggt ggcggtaacg gtggcattgg gcagcggttc
    19981 gccacggaac agaacgcgga ctttgaagcg ttcgcctacg tgaatgttgg cgggattgtc
    20041 cagcgggacg atttccaagt tttgtccgac cggtttggtg atgatggcgg tgtccgcgct
    20101 ttcgtgtccg acgttgacga tgtttttgcc gaacatacgg gtttgttcgc aatagcttgc
    20161 gtcaggcatt tctttgatgc ccgcctgttt ccagcctgct ttgttttttg accagaaagt
    20221 aggctgatat tcggcgatga cgaggtaact gccgtcctta acgggacggt tgcttcggta
    20281 ctggtagttg tatgtgccgc gttgaatcat gttttccttg cctttttcgg taaccagctg
    20341 catcggtttg ctgaagatgt gcaggcggtc tttggcgatg ggttcgagtt cgggaaattc
    20401 gccgtagccc aagtcggctt taaggtattc gccgccgtgc gtgtgggcgg tttcgaccca
    20461 gacgcggtgg gcgtgggcgg atgtggcaaa tagggcggaa acggcgagca gtgtcaatgt
    20521 tttcttcatg gtgcagcctt tgtctcgtgt gggttaaaga ttttgttatg ttataacaaa
    20581 ataggtatcg tgtgaagacg gatttgctgt ctgaaaactg tctttttgta tagtggatta
    20641 acaaaaacca gtacggcgtt ggctcgcctt agctcaaaga gaacgattct ctaaggtgct
    20701 gaagcaccaa gtgaatcggt tccgtgctat ttgtactgtc ttcggcttcg ccgccttgtc
    20761 ctgatttttg ttaatccgct atatcgattt gaatttttca gaaaatgaag cggacgtttg
    20821 ggcggaggca acttgtttga taagatagca atatttcaaa acggagaaag atcatgcctt
    20881 atgtcaatat taaagtaacc ggcggcaagg aagcaccgac tgccgcgcaa aaagcggaac
    20941 tgatcggcgg cgtaaccgaa ttgctggcac gcgtgctggg taaaaatccc gaaacaacgg
    21001 ttgtcgtgat tgacgaagtg gataccgata actggggaat aggcggcaaa agcgtcagcg
    21061 aacggcgcaa agagggcagg taaaaagcct gaaaatctcg gtttgatgct ttaaattccg
    21121 cgtgaaaaag agtacattcc cacccattgc ccaaaattta cggaacacat catggataaa
    21181 tttcccaagt ctgcaaagct cgatcacgtc tgttacgaca tacgcgggcc ggttcacaaa
    21241 aaagcccttc agttggaaga ggagggcaat aaaatcctta aactcaatat cggcaaccct
    21301 gcgccgttcg gctttgaagc ccctgatgaa atcttggtcg atgtcatccg caacctgccg
    21361 acttcgcaag gctattgcga ttccaaaggg ctgtattccg cccgcaaagc cattgttcac
    21421 tactatcaga ccaaaggttt gcgcgatatt acggttgatg atgtctatat cggcaacggc
    21481 gtgtccgagc tgattacgat gtctatgcag gcattgctca acgacggcga cgaaatcctg
    21541 attcccgcgc ccgactaccc tttgtggacg gcggcggcaa cgcttgcggg cggtacggta
    21601 cgccattatc tgtgcgacga agaaaacggc tggttcccca accttgccga tatggaagcc
    21661 aaaatcacgc ccaaaactaa agccatcgtc gtcatcaatc ccaataatcc gacaggcgcg
    21721 gtgtacagca gggaaatcct gttggaaatc gccgaactgg cgcgcaagca cggtttgatt
    21781 attttcgccg acgagattta cgataaaatc ctttatgacg gcgcggttca ccaccacatc
    21841 gccgcgctcg cccccgacct tttgacggta acgttcaacg gtttgtccaa agcctaccgt
    21901 gtagccggat tccgccaagg ctggatggtg ctcaacgggc cgaaacatca tgcaaaaggt
    21961 tacatcgagg gtttggatat gctctcgtcc atgcgcttgt gtgcgaatac gccgatgcag
    22021 catgcgattc agacggcatt gggcggttat cagagcatta acgaattcat tttgcccggc
    22081 ggacggcttt tggaacagcg taacagggcg tgggaattgg tcaatcagat acccggcgta
    22141 tcctgcgtca aacctatggg cgcgatgtat atgttcccaa aaatcgatac cgaaatgtac
    22201 cgtatccacg atgacatgaa attcgtttac gatttgctgg tgcgcgaaaa agtcttgctg
    22261 gtgcagggaa cggggtttaa ttggattaaa cctgaccatt tccgcattgt cacgctgcct
    22321 tacgtccatc agattgaaga ggcgatgggc aggttggcaa gattcctgca aacctaccgc
    22381 caataaggga cggtttgtct gccgaggata aaaaatgccg tctgaaacgg agattcccgt
    22441 ttcagacggc attttcaaca gcaggaacga atcaggcaaa tttcagtctg tcgccgtcgg
    22501 cttctaccct gatttcgctt tcgggcgcat agtttccggc aagcagggct tttgccagcg
    22561 ggttttcgat ttccgactgg atggcgcgtt tgagcggacg tgcgccgtaa atcgggtcga
    22621 aaccggcttt ggcgatgatg tccagtgcgg catcggaaac agtcaggcgc aggttttgtt
    22681 tttccaaacg tttttccaaa cctttgagct ggattttcgc aatgctgcgg atgtttgcct
    22741 gatccaaacc gtggaacacg accacttcgt cgatgcggtt gatcatttca ggacggaaat
    22801 gttctttcac atcctccatc acaacttctt ttaccgcttc gtaatcctga atgcccattt
    22861 gttggatgtg ctggctgccg atgttggaag tcatcacaat cacggtattt ttaaaatcta
    22921 ccgtcctgcc ttgcccgtcg gtcaaacgac cgtcatccaa tacttgcagc aggatgttga
    22981 acacatcggg atgggctttt tccacttcgt ccagcagaat cacgctgtac ggtttgcggc
    23041 gcacttgttc ggtcaggtag ccgccttctt cgtagccgac atagcccgga ggcgcaccga
    23101 tcaggcgtgc aacggcgtgt ttttccatat attcggacat atcgatgcga atcagatgat
    23161 cttcgctgtc gaacagaaag cctgccaggg ctttacacaa ctcggtttta cccacgccgg
    23221 tcgggcccaa gaacaggaag ctgccgtaag gcttgttcgg atcggcaaga ccggagcggc
    23281 tgcggcggat agcgtcggac acggcacgca cggcttcgtc ctgtccgacc acgcggcggt
    23341 gcaatacttc ttccattttc agcagtttgt cgcgttcgcc ttccatcatt ttggatacgg
    23401 gaatgccggt catacgggaa accacctctg cgatttcctc tgcgccgaca ttattacgca
    23461 agagtttgtt tgccggtttt gtgctgtccg tatctgcccg ttcggcggct gcacgctgtt
    23521 tttccaaatg ctccaaatct tcatacatca attttgaagc cagtgccaaa tcgccttgcc
    23581 gttttgcctg ttcgatttta attttgactt cgtcaatttg tttcttaata ttagcagcac
    23641 cgtctgaaat tgctttttcg gctttccaga tttcgtctaa atcggcgtat tctttttgca
    23701 gaccgttgat ttcctcgtct atcagttcca aacgtttttt gctggcatcg tctttttctt
    23761 tttcaacgtg cgccttttcc atccgaagct gaattagacg gcggtcgatt ttgtccattg
    23821 cttccggctt ggtttctttt tccatcttga cacggctggc ggcttcgtca atcaaatcaa
    23881 tcgctttatc aggcaggaag cggtcggtaa tgtagcggtc gctcaactcc gctgcggcaa
    23941 cgatagcagg gtcggtaata tcgataccgt ggtggatttc ataacgctcc tgtaaaccgc
    24001 gcaagatagc gatggtgtct tctacacttg gctcgccaac caatactttt tggaagcggc
    24061 gttcgagtgc cgcgtctttt tcgatgtatt ggcggtattc gtccaaggtg gtcgcgccga
    24121 tacagtgcaa ttcgccacgt gccaaagccg gtttcagcat attgcccgca tccatcgcac
    24181 cgtcggtttt gcctgcgccg accaaagtat ggatttcgtc gatgaaaatc agagtgttgc
    24241 cgtcgtcttt cgccaagtcg ttcaacacgc ctttcaagcg ttcttcaaat tcgccgcggt
    24301 atttcgcgcc ggcaatcaat gccgccaagt ccaaaaccag taggcgtttg ttgcgcaggg
    24361 attcgggtac ttcgccgttg acgatgcgtt gtgccaaacc ttcgacgatg gcggttttac
    24421 ccacgcccgg ttcgccaatc agcacagggt tgtttttggt acggcgttgc aatacctgaa
    24481 tcgcacggcg gatttcgtcg tcacggccga taacggggtc gagcttaccg tctcgggcgc
    24541 gttgggtcag atcgagcgta tattttttca aagcatcgcg ttggtcttcg gcattggcat
    24601 cgttcacgtt ttgtcctcct cgtaccgcgt caatcgcggc attgatgttt tgttcggtcg
    24661 cgccggcttc tttcaaaatt ttgccggccg catcgttctg ctgcaccaag gcaagcagga
    24721 aaagttcact ggcgatatag gcatcgccgc gtttggttgc ggctttgtcc atcaggttca
    24781 acaccgcctg caattcgcgg ctgggcagaa tgtcgccgcc ctggccggac actttcggca
    24841 ggctgttcaa atgctgctgc aaacgctgtt tcacctgcgg cacgttcacg cccgcatgag
    24901 ccaagagcgc ggcagcaccg ctgttttggt cgtcaagcag ggctttcagc acaaagcccg
    24961 cttccagata gctgccgtcc gcagccaacg ccaaactctg agcttctgca agggcctgtt
    25021 ggaatttggc ggttaatttg tcgtatcgca tttttgtttc cttttcaaaa tgtccgctgt
    25081 cgaagcctat atgtgcataa ttgtggataa ctcaagttct gttttctgtt tttctatatt
    25141 taattcgata tatcattgaa tttaaagtat ataaaaatgt ataataatgt gtataactat
    25201 atcttcttaa tatggaaaag tctgttgtcg gctggatgta ggtggcaaat cgggtataat
    25261 cggcgcatct ttttcccttt cagacggcat tgatgccgca aggacatttt tatgagcaaa
    25321 aaacgagttc tgaccggcgt aaccaccacc ggcatcccgc atctgggcaa ctacgtcggt
    25381 gctatccgcc ccgccgtccg cgcggcgcaa aaccctgata ccgaatcctt cctcttcctc
    25441 gccgattacc acggtatcat caaatgccac gagccggaga tgattcacca atccacccaa
    25501 gccgttgccg ccacttggct tgcctgcgga ctcgaccccg agcgcaccac cttctaccgc
    25561 caaagcgaca ttcccgaagt gatggaattg aactggattc tgacctgcat caccgccaag
    25621 ggtttgatga accgcgccca cgcctacaaa gccgccgtgc aggcaaatgc ggaaaacggg
    25681 caggaagacc ccgatttcgg cgtggaaatg ggtttgttca gttatccgat tctgatgact
    25741 gccgatattc tgatgttcaa cgccaacgaa gtccccgtcg ggcgcgacca aatccaacac
    25801 gtcgaaatgg cgcgcgacat cgccggccgc ttcaatcacc gcttccgaga actcttcacc
    25861 ctgcccgaag tgaaaatcga cgaaaacgtc gaactcttgg tcggtttgga cggacgcaaa
    25921 atgtccaaat cctacggcaa caccattccg ctttgggaaa acgacaaaaa aacccaaaaa
    25981 tcggtcaaca aaatcatcac caatatgaaa gagccgggcg agccgaaaca gcccgacgaa
    26041 agcccattgt ttgaaatcta caaagccttc tccacgccgt ctgaaacggt ggaatttacg
    26101 aaaatgcttg ccgacggcct ggcttggggc gaggcaaaaa aacttttggc ggcgaaaatc
    26161 aacgccgaac tcgccgaacc gcgcgaacgc tacaacgagc tgaccgccga cccttcgcaa
    26221 atcgaagaga ttttacaggc aggtgcgcaa aaagcgcgta aagaagcacg cgaattgttg
    26281 gacaaagtac gcgatgcggt cggcatccgc ccgttgaaat aaacccgatg ccgtccgaac
    26341 ctcttaaagg cttgccggaa caaaacgtcg tccggctgac cggcaagcat cccaacgact
    26401 tggaagccgt cagcggcaaa tgcatggaaa ccgacgataa gggcggtccg gtaggctggg
    26461 cggaaaacgg cgtgtgccat accttgtttg ccaaactggt gggcaatatc gccgaagacg
    26521 gcggcaaact gacggattac ctgatttcgc attccgccct gcaaccctat caggcaggca
    26581 aaagcggcta tgccgccgtg cagaacggac gctatgtgct ggaaatcgac agcgaagggg
    26641 cgttttattt ccgccgccgc cattattgag gtattcggac atcccggaat atatttgggt
    26701 ttttcaaacc ctgcgggaaa aaagtccgca ccgtcgggaa actcaaaagg agggggatat
    26761 gtgttacaat tttccgaact gttttcataa aatagttttc ggacgtgttt caatatggca
    26821 ttgatgccgc cttattgttc gagaaaaaaa acctttatat ttaaatataa tgggttttaa
    26881 ctaaacggga aaccgttttc tctccggccg atgggcaaaa tcagccgatt gatggaacac
    26941 ggtccgattt ttaagcaaaa ccttaatcaa caactcaaga aggataagac atgaaaaaat
    27001 tattgattgc cgcaatgatg gcggctgcct tggcagcttg ttcgcaagaa gccaaacagg
    27061 aggttaagga agcggttcaa gccgttgagt ccgatgttaa agacactgcg gcttctgccg
    27121 ccgagtctgc cgcttctgcc gtcgaagaag tgaaagacca agtcaaagat gctgcggctg
    27181 atgcaaaggc aagtgccgag gaagctgtaa ctgaagccaa agaagctgta actgaagcag
    27241 ctaaagatac tttgaacaaa gctgccgacg cgactcagga agcggcagac aaaatgaaag
    27301 atgccgccaa ataatttgtt gccttggcaa aaatgatggg atgccgcctg ccggcaaccc
    27361 aaacgaaacc gcctgaagat tttcaggcgg tttttgagtt gtatgcccct tgttttttac
    27421 gcctgcatga ccgttccgag cagatgtgcc gcgcatatcg ggatgttgcg gacaggcaaa
    27481 tgccgtctgg acagggtttg gacggcattt gttccgtaag gttcagacga cctcgacttt
    27541 aaacggcata ttgatttttt gccattggac gctttcatat tccaatgcgt cggcaatcag
    27601 gggatggcgt tccagccatt ccctgtcaat acgcaggatg aagccgcagc tttccgtatc
    27661 cgtgcgcaac tgcatatttt tcgggaaaga caggtcttgg cgcgaacggc agaacagggc
    27721 agcaaggcgc agggacaaaa cggcatacca caacatttcg ttggtgccga tgatgccgct
    27781 catttttttc atatcgccgc gatgaccgat gaccagttgg gcaagtatgg tctgttcttt
    27841 gcgtgagaaa cccggcatat cggcgttttc gaggatgtag gcggaatgct tgtgatagcc
    27901 ggtgtgggcg atgtccaaac cgatttcgtg cagcgcggcg gcgcgtccga gatactgttg
    27961 ccacaaggca agctcttgaa ctgtaacgtt tttagcgtgg cagaggctgt ccataaaggt
    28021 ttgcgcggtc tcggcggtgc gtttcgcctg attgaggctg acgtggtagc ggtgttggaa
    28081 ctcggcaacc gtttgtccgc gcatatcttc gtttaaaccg cgcccgatca aatcgtaaaa
    28141 cacgccgtcg cgcagggcgg cttcggttac ggtcatcctg tcgagtttca tttcctcaaa
    28201 cgccgccatc atcacggcaa gtccgccggc aaaaacttcg atgcgttccg gtttcaggtt
    28261 ttcaaatttg gcttttttga ccgaaccggc ttcgatgatg cgttcggaga gggcgcgcat
    28321 acctttgtag gtaatgtccg cctcttgggg catttcggcg gcaagcacgt cgcggatgga
    28381 ttttgccgaa cccgatgtgc cgacggcgaa atcccagcct tcgcgcctca tatttttgct
    28441 gatgcgctgg atttcgttgc gggcggcgga aatggcggct tggaagtctt tggcggtgat
    28501 tttgttttgg aagaagcgca ggctgtaggt tacgcagccc aagggcaggc tttcggtaat
    28561 gtcgggattc agcgtcgaac cgatgacaaa ttctgtcgaa ccgcccccga tgtcgataac
    28621 cagcattttg ccgccgccgg gggggagggt gtggatcacg ccggtataaa tcagccgtgc
    28681 ctcttcgcgc ccggcgatga tttcgatggg gaaacccagt gccgcttcgg ctttgggaag
    28741 gaaatctgcg atgtttttgg cgacacggaa tgtattggtt gccacggcgc gtacctgttc
    28801 agggcggaag ccgcgcaggc gttcgccgaa ttttgccaga cagtccaaag cctgttcttg
    28861 ggaagcggca ctcaggtttt tctgttcgtc cagtccggcg gcgaagcgca ccatctgttt
    28921 gaacgaatcg atgactttca actgtccgtt gttgttttcg caaatctgga ggcggaaact
    28981 gttagaaccc aaatcgacgg aggcaaggac gtttgcgggg gtggtggtca tggcggatac
    29041 cggtggggga aaaacgcaat gttactctga cggcgcaggc gttgacaata aatgatgcgg
    29101 cggtttttga ttctgcccac ggatgttgcc gacggcattt ttgcgcttat ttgaaatcct
    29161 tttccacgct catgaaaatc tgcgtgtttt tgcgtgtgta aaaacttttc atattgctgt
    29221 cgattttcag atagcggaaa ttgagttgcg gcgtaaagcc cttccaagag attttgtcgt
    29281 gccacaacga caggtttgcc tgatattcgt ggtctttgcg cgggaagcgg tacacaatgg
    29341 tcccgggtgc gtcaaacatc ctgcgggtat agcgcaggtt tgcccgcaga cccaagcccg
    29401 ccgtcgaacg ttttgactgc gccgacacgc aaacccttgc ggacggaagc ctgttccgcc
    29461 tctttcgtca tgttgtgcga ccagtccgca ccgccgtaaa gcagccagtc tttcggcgcg
    29521 gaatacatca gcgtcgcgcc cgccagcggc atatggctgt cgtatcgggc ggcggtgcgg
    29581 tcttcctgat aacgcttcca catattgccc gcgtttagtg tcaaccgcca gcgttcgccc
    29641 aagcgttggg agaaatcggc attgaagccg ccgacgaaat tgtatcggct gccgcctaag
    29701 aggttttgcc cgacaaacgg cacgatgccg aacgagcgcg ttaccgaacg atttttatag
    29761 ccgagcgaca ggtgcaggca ctgttcgctg aaatctttgt tatcccaata atgcacgccg
    29821 ccgccgctga tgccgccgta gaggaaatga tgcccgcccg cattgatttc gcgcgacacg
    29881 cctaagccct agcgcaaacc gtgtgccttt tgcggcaggc tgtcggcggt tttcgtccag
    29941 cttctgcccg caaattcaat cgtttttttg gacgaagcgt tgtttatagc ggattaacaa
    30001 aaatcaggac aaggcgacga gccgcagaca gtacaaatag tacggaaccg attcacttgg
    30061 tgcttcagca ccttagagaa tcgttctctt ttttgttcat ccgctatatt gtgttgaaac
    30121 atcgccacaa acctgatata gtccgctcct gcaacatcat tgaaaatcgt tctttttaat
    30181 cagttaaaac cgaatacgga gtcgaaaatg aatccagccc ccaaaaaacc ttctcttctc
    30241 ttctcttctc ttctcttctc ttctcttctc ttctcttctc ttctcttctc ttctcttctc
    30301 ttccgcagcg caggcggcaa gtgaagacag cagccgcagc ccgtattatg tgcaggcgga
    30361 tttagcctat gccgccgaac gcattaccca cgattatccg caagcaaccg gtgcaaacaa
    30421 cacaagcaca gtaagcgatt atttcagaaa catccgtgcg cattccatcc accctcgtgt
    30481 gtcggtcggc tacgacttcg gcggctggag aatagcggca gattatgcca gttacagaaa
    30541 atggaacgac aataaatatt ccgtcaacac aaaagaggtg ctaagaaaca atagcactgg
    30601 cactgaaaac tggcaagaac tgaagacgga aaatcaggaa aacggcagct tccacgccgc
    30661 ttcttctctc ggcttatc
//
LOCUS       DAXISH010000017        29208 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.017, whole genome shotgun sequence.
ACCESSION   DAXISH010000017 DAXISH010000000
VERSION     DAXISH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 29208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29208
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.017"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            1..149
                     /locus_tag="ACFOV4_000796"
                     /pseudo
     CDS             1..149
                     /locus_tag="ACFOV4_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(159..1268)
                     /gene="mltB"
                     /locus_tag="ACFOV4_000797"
     CDS             complement(159..1268)
                     /gene="mltB"
                     /locus_tag="ACFOV4_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HFC7618843.1"
                     /translation="MKKRKILPLAICLAALSACTAMEARPPRANEAQAPRADEMKKES
                     RPAFDAAAVFDAAAVPVSDSGFAANANVRRFVDDEVGKGDFSRAEWQDFFDKAAYKAD
                     IVKIMHRPSTSRPWYVFRTGNSGKAKFRGARRFYAENRALIDDVAQKYGVPAELIVAV
                     IGIETNYGKNTGSFRVADALATLGFDYPRRAGFFQKELVELLKLAKEEGGDVFAFKGS
                     YAGAMGMPQFMPSSYRKWAVDYDGDGHRDIWGNIGDVAASVANYMKQHGWRTGGKILV
                     SATLAPGADVQAIIGEKTALTRTVADLKAYGIIPGEELADDEKAVLFKLETAPGVFEY
                     YLGLNNFYTVWQYNHSRMYVTAVRDIANSLGGPGL"
     gene            complement(1265..1447)
                     /locus_tag="ACFOV4_000798"
     CDS             complement(1265..1447)
                     /locus_tag="ACFOV4_000798"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618844.1"
                     /translation="MPSERGSAFRRHFRRRQADFGRRKRQRAAFCKAADCGGYRISRR
                     ALAPLSHLPYLFGTYL"
     gene            complement(1469..2896)
                     /locus_tag="ACFOV4_000799"
     CDS             complement(1469..2896)
                     /locus_tag="ACFOV4_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HFC7618845.1"
                     /translation="MIHTEPSAQPSTMDTAAFLKHIESAFRRIFSDGIDLMRYLPEDK
                     WLALKQAGLLLPFLDKKHGGRKGSQFEIQEVLRIAGHYGVPVTLRTGIEGALVLQPLQ
                     EFGDEAQIAQGLDMVFKGEGGGLGVTEPETSGAAIAREMQSYYEYTDGQTIYVNAAKY
                     WQGNSQSDFLLVAAKERKNGKLAKVIDLLLVPKTYIRCETLASEGLRAVRYAVNRIDA
                     EMPATAVMKLSQSDAAGLRAFQNIFIRSRLQLIGMTHGIMEYILENLERYVRNDIRFV
                     DYERREIRRRHQVSEILYRYVCHSVSPVAPVAHQLMEANIVKTLATEYTYAAAQMLQK
                     LLGAKGFERGHTAGNIAIDIRPFTIFEGPNDMLYAEIYDQFVRATAEEKEAGMKLDKN
                     QTLLDRLQTDARFAAVARDYTLPEDIRSFLQEHTLTDACALQKVFIGKIIARLFVFVQ
                     AEHEDAAACLLNDIRKDILDCRYCG"
     gene            3081..7220
                     /gene="mfd"
                     /locus_tag="ACFOV4_000800"
     CDS             3081..7220
                     /gene="mfd"
                     /locus_tag="ACFOV4_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFC7618846.1"
                     /translation="MTYPIPKPREKSRWSNLSQGSLPLALARYLPHKRLKVVLTQDAE
                     QALRLQTAWRFFRPHDTAVFLPDWETLPYERFSPHQDLVSERLSALWQIKSGAADVLF
                     VPVATAMQKLPPVPFLAGRTFWLKTGQTLDIGRLKTDLVDAGYNHVSHVVAAGEFAVR
                     GGIVDLFPMGSEMPYRIDLFDDEIDSIKTFDTDTQRTISPVSEIRLLPAHEFPTDSEA
                     QKIFRSRFREEVDGNPNDAAVYKAVSNGHFGAGVEYYLPLFFENELETLFDYIGEDAL
                     FVSLGDVHAEANRFWSDVKSRYAMAQGDETYPPLLPQHLYLSADVFAGRLKNYGQVLP
                     DVSGKEHALPDLAVNRQSDEPLQALKDFQTAFEGRILLCAESLGRRETMLGFLQQNGL
                     KAKPVSDWQGFLSAHEPLMITVAPLAYGFKLGGLQSPNQQQTTSASEGEGDAVTDQTE
                     FSASATNPLPSPLPQEREQSAAVVSDSLKAAAVSTESRLPPGKSNLHGQIQQQPTPSP
                     VGEGWGEGKAVAAQTEFSAAAISPLPSPLPSPLPQEREQSAAAVSDGLKTESSLYSIA
                     NNLHGQIRQQPTPSPVGEDWGESKTVAAQTEFPASATNPLPSPLPQEREQSAAVVSDS
                     LKAAAVSTESSLPPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQSAIAVITESDLYQ
                     YVARSRAHNRRKKHAAVSDGLLRDLAEINIGDPVVHEEHGIGRYMGLITMDLGGETNE
                     MMLLEYAGEAQLYVPVSQLHLISRYSGQAHENIALHKLGSGAWNKAKRKAAEKARDTA
                     AELLNLYARRAAQSGHKFEINESDYQAFADGFGYEETEDQAAAIAAVIKDLTQAKPMD
                     RLVCGDVGFGKTEVALRAAFVAVMGGKQVAVLAPTTLLVEQHAQNFADRFADFPVKVA
                     SLSRFNNSKATKAALEGMADGTVDIVIGTHKLVQDDIKFKNLGLVIIDEEHRFGVRQK
                     EQLKRLRANVDILTMTATPIPRTLSMALEGLRDFSLITTAPSRRLAVKTFVKPFSEGS
                     VREAVLRELKRGGQVFFLHNEVDTIENMRERLETLLPEARIGVAHGQLRERELEQVMR
                     DFLQQRFNVLLCSTIIETGIDIPNANTIIINRADKFGLAQLHQLRGRVGRSHHQAYAY
                     LLTPEYITKDAEKRLDAIAAADELGAGFTLAMQDLEIRGAGEILGEGQSGEMIQVGFT
                     LYTEMLKQAVRDLKKGRQPDLDAPLGITTEIKLHSPALLPESYCPDIHERLVLYKRLA
                     VCETVQQINAIHEELVDRFGLPEQPVKTLIESHHLRLMAKELGIDAIDAAGEAVTVTF
                     GKNNNVDPTEIILLIQNDKKYRLAGADKLRFTAEMENIEVRINTVKNVLKTLQNRCLP
                     K"
     gene            7369..7752
                     /gene="panD"
                     /locus_tag="ACFOV4_000801"
     CDS             7369..7752
                     /gene="panD"
                     /locus_tag="ACFOV4_000801"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HFC7618847.1"
                     /translation="MFRTMLGGKIHRATVTEADLNYVGSITVDQDLLDAAGIYPNEKV
                     AIVNNNNGERFETYTISGKRGSGVICLNGAAARLVQKGDIVIIMSYVQLSEPEIAAHE
                     PKVVLVDGNNKIRDIISYEPPHTVL"
     gene            7774..8616
                     /gene="kdsA"
                     /locus_tag="ACFOV4_000802"
     CDS             7774..8616
                     /gene="kdsA"
                     /locus_tag="ACFOV4_000802"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008676 - 3-deoxy-8-phosphooctulonate
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HFC7618848.1"
                     /translation="MDIKINGITVGNDAPFVLFGGINVLEDLDSTLQTCTHYVEVTRK
                     LGIPYIFKASFDKANRSSIHSYRGVGLEEGLKIFEKVKAEFGIPVITDVHEPYQCQPV
                     AEVCDVIQLPAFLARQTDLVVAMAKTGNVVNIKKPQFLSPSQMKNIVEKFHEADNGKL
                     ILCERGSSFGYDNLVVDILGFGVMKQTCGNLPVIFDVTHSLQTRDAGSAASGGRRAQA
                     LDLALAGMATRLAGLFLESHPDPKLAKCDGPSALPLHLLEDFLIRIKALDDLIKSQPI
                     LTIE"
     gene            8631..9071
                     /locus_tag="ACFOV4_000803"
     CDS             8631..9071
                     /locus_tag="ACFOV4_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4149 domain-containing protein"
                     /protein_id="HFC7618849.1"
                     /translation="MMQTFRKISRYVATLWLGMQIMAGYIAAPVLFKMLPKMQAGEIA
                     GVLFDILSWSGLAVWGAVLAAAFAILTRLQTALLLFLLSALAANQFLVTPVIEALKYG
                     HENWLLSFVGGSFGMWHGISSMIFMATALLSAVLSWRLSGKDAV"
     gene            9119..10405
                     /gene="eno"
                     /locus_tag="ACFOV4_000804"
     CDS             9119..10405
                     /gene="eno"
                     /locus_tag="ACFOV4_000804"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFC7618850.1"
                     /translation="MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTG
                     QKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTEN
                     KGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSL
                     NIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEA
                     LQLMVEATEAAGYKAGEDVLFALDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLV
                     NEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPKILAEGIEKGVANAL
                     LVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSL
                     SRSDRMAKYNQLLRIEEELAEAADYPGKAAFYQLGK"
     gene            10419..10697
                     /gene="ftsB"
                     /locus_tag="ACFOV4_000805"
     CDS             10419..10697
                     /gene="ftsB"
                     /locus_tag="ACFOV4_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HFC7618851.1"
                     /translation="MKWVTVVLSFALVCCQYSLWFGKGSIGRNSSLREQIAVQEEKNQ
                     TLALRNHSLAAEVYDLENGQEAISEIARVELGYIQDGETFYRLIRHNR"
     gene            complement(10738..11028)
                     /gene="yfaE"
                     /locus_tag="ACFOV4_000806"
     CDS             complement(10738..11028)
                     /gene="yfaE"
                     /locus_tag="ACFOV4_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I ribonucleotide reductase maintenance
                     protein YfaE"
                     /protein_id="HFC7618852.1"
                     /translation="MARIGTNKGFFELLEGETLLEGLERTGHMVEYQCRSGYCGSCRV
                     KILEGSVTYREPPLAFLGRDEILPCCCCVEGDVRLDCGLSGEDEGLSDSLLK"
     gene            complement(11226..12359)
                     /gene="nrdB"
                     /locus_tag="ACFOV4_000807"
     CDS             complement(11226..12359)
                     /gene="nrdB"
                     /locus_tag="ACFOV4_000807"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ia ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFC7618853.1"
                     /translation="MSYSTFPKTKNDALNEPMFFGQPVNVARYDQQKYEVFEKLIEKQ
                     LSFFWRPEEIDVSRDRIDYANLPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLVSI
                     PELETWIETWSFSETIHSRSYTHIIRNIVNDPSVVFDDIVENEYITARAEDIACYYDD
                     LIEYTQYYNLLGEGVHNVGGKPVTVSLRGLKKKLYLCLMCVNVLEAIRFYVSFACSFA
                     FAERELMEGNAKIIKLIARDEALHLTGTQHMLNLMRSGVDDSEMAEIAAELQDECFQL
                     FKKAAEQEKEWAAYLFKDGSMIGLNKEILSQYVEYITNLRMQAVGLPAGFEGANQNPI
                     PWINAWLSSDNVQVAPQEVEISSYLIGQIDSEVNTDDLGDFEL"
     gene            complement(12420..13607)
                     /locus_tag="ACFOV4_000808"
     CDS             complement(12420..13607)
                     /locus_tag="ACFOV4_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HFC7618854.1"
                     /translation="MNDLAAQTIQVVNKSDDLVASAIQTANKSIAVYCRYIRPNDVGT
                     TGSHQSGFYIQKHFSDDLFDVVCQKGTNKTISIKINWQDGSVTNSNFKYYGQGTRNEA
                     RITGFGKNFEFLSDKYSGSLLVLCRACYKDLLFHAFVLSSDEDIEIFIAETNILPGSL
                     YLPKKQEVEDNLTKLFSLFPNFPKTEEMAVLARENIALNKTNVSNVLKQWVSKEYELF
                     SIFEKREFEIIKSKITDLDSFINFAHSFTNRRKARAGKSLELHLSRIFDEFSLKFETQ
                     AKTEGKKKPDFLFPGSEEYHAMDESGNFIFQTEKLTMLGSKTTCKDRWRQVLNEADRI
                     PHKHLFTLQEGISDTQIQEMSDENLTLVVPKESVKTFGTFGKTHVLTLENFIKYIKSQ
                     QVS"
     gene            complement(13604..14614)
                     /gene="dcm"
                     /locus_tag="ACFOV4_000809"
     CDS             complement(13604..14614)
                     /gene="dcm"
                     /locus_tag="ACFOV4_000809"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFC7618855.1"
                     /translation="MKNKIQNQLDNIVTLNNEKFTFIDLFAGIGGFRIAMENVGGRCV
                     FSSEWDDKARQTYQVNFNDIPYGDITLKETKAAIPSKFDVLTAGFPCQPFSIAGVSKK
                     KSLGRETGFLDKAQGTLFFDVAEIIGKHRPKIFLLENVKNLVSHDKGNTFKVIKGTLE
                     ELDYQIFYQVMNAKYYVPQNRERIFIVGFDRQYFNKEINFNFPSPPESQPKLKQILED
                     DVDNSFTLSDNLWLYLQNYAKKHKAKGNGFGFGLVDLDGISRTLSARYYKDGSEILIP
                     QKGKNPRKLTPRECSRLMGFPKDFVIDAVSKTAAYKQFGNSIAVPLVQAIAKQIINEL
                     KK"
     gene            complement(14672..16951)
                     /gene="nrdA"
                     /locus_tag="ACFOV4_000810"
     CDS             complement(14672..16951)
                     /gene="nrdA"
                     /locus_tag="ACFOV4_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1a ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFC7618856.1"
                     /translation="MNTPTDLKVTKRDGRLEAIDLDKIHRVVTWAADGLENVSVSQVE
                     LKSHIQFYNGIRTDDIHETIIKAAADLISEDTPDYQYLAARLAIFHLRKIAYGEYEPP
                     HLYDHVKKLTDAAKYDRHILEDYSREEFDELNAYIDHERDMSFSYAAVKQLEGKYLVQ
                     NRVTRQIYETPQFLYVLVAMCLFSKYPKETRLDYVKRFYDAVSTFKVSLPTPIMSGVR
                     TPTRQFSSCVLIECDDSLDSINATTSAIVKYVSQRAGIGINAGRIRGLDSEIRGGEAR
                     HTGCIPFFKMFQAAVKSCSQGGVRGGAATLFYPLWHIEAESLLVLKNNRGVEDNRIRQ
                     LDYGVQINRLLYTRLIKGGNITLFSPNEVPGLYEAFFADQDEFERLYTKYEQDPDIRK
                     RIIPAADLFSTLMQERAGTGRIYIQNVDHCNTHSPFDPRVAPVHQSNLCMEIALPTKP
                     LDNINDPNGEIALCTLSAFNLGALNSLDELEGLADLTVRALDALLDYQGYPVEAARTS
                     TMGRRSLGIGVINYAYYLAKNGVRYSDGSALGLTHRTFEAIQYYLLKASANLAKEYGA
                     CTLFNQTVYSQGKLPIDTYKKDLDAVCGEPLHYDWESLRAEIVKYGLRNSTLTALMPS
                     ETSSQIANATNGIEPPRGLVTVKASKDGILKQVVPEFETLKNAYETLWQLPGNEGYLK
                     LVGVMQKFVDQSISANTAYDPGKFEGGKVSMKQMLKDLLTAYKYGVKTLYYHNTRDGA
                     DDTQTDIQDDGCAGGACKI"
     gene            17480..17791
                     /locus_tag="ACFOV4_000811"
     CDS             17480..17791
                     /locus_tag="ACFOV4_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein"
                     /protein_id="HFC7618857.1"
                     /translation="MLAILLSAILGLVSTTAAAGTSEPAHRDTKHIRKANKQMLHPEC
                     RKYLERRAAWYRSQGNVQELRENKKARKAFHSLPYAEQKIQCRAAYEAFDDFDGGSFR
                     R"
     gene            complement(18103..18870)
                     /locus_tag="ACFOV4_000812"
     CDS             complement(18103..18870)
                     /locus_tag="ACFOV4_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HFC7618858.1"
                     /translation="MSSNKASFFTRLRRLCRLAVWLFKTGKNLRGIDGGCPESRNRAV
                     IELGRGVLAALDIGLEVGRPAPEHPNGVLVAANHVSWLDIFAMSAVYPSSFIAKQEIK
                     SWPVLGKMGQNAGTVFINRNSRRDIEPINRAVCETLQRGQNVSFFPEARTSSGLGLLP
                     FKAALFQSAIDAGAKVLAVALRYYDETGKRTARPSYADVGLPTCLWRIVSMKKLTIKV
                     DFVCVADAAESEDRYALKDKIEESIRAVVADDADIAV"
     gene            complement(18958..19785)
                     /gene="mutM"
                     /locus_tag="ACFOV4_000813"
     CDS             complement(18958..19785)
                     /gene="mutM"
                     /locus_tag="ACFOV4_000813"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFC7618859.1"
                     /translation="MPELPEVETTLRGIAPHIEGKTVEAVVLRQLKLRWQINPDLGEI
                     LSGRQVLSCGRRAKYLLIRFQTGVLLIHLGMSGSLRIFTPSDGRIGRPDRHDHVDIVF
                     SDGTVMRYRDPRKFGAILWYEGIEEHHPLLEKLGPEPLSEAFCADYLYARLKAQKRAV
                     KLALMDNAVVVGVGNIYANESLFRAGISPYRPANRLKKKECALLVETVKAVLRRAIET
                     GGSTLRDFVDSDGKSGYFQQEYTVYGRHNQPCPQCGGLVVKETLGQRGTFYCPNCQK"
     gene            complement(19837..20502)
                     /locus_tag="ACFOV4_000814"
     CDS             complement(19837..20502)
                     /locus_tag="ACFOV4_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HFC7618860.1"
                     /translation="MDAWFEDTAMGRYVAKLEQDFFGRYLDSYRFSGMCAVQVGGRWL
                     SLSEDVVCVPRDMSMSAENMALADVSADMLLFPHTLEGGVPSQILSEAHRILKPCGRL
                     MLTGFNPYSLWGFSRWFDGERLPEKRFCLPLPELKRRLADAGFDIEFGKFMVYLPPVS
                     SLGQIRFWRFMEKAGDRWWPQCAAVYALVLVKRAAGVTPLPAWDGYLGGKALAAGAAR
                     VAD"
     gene            20681..22657
                     /locus_tag="ACFOV4_000815"
     CDS             20681..22657
                     /locus_tag="ACFOV4_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFC7618861.1"
                     /translation="MSKLKTIALTASGLSVCPGFLYAQNTSSHQIGLAIMRLNSSILD
                     LPPTKQYFQSGSLWSELRQGFRMGEVNPELVRRHESKFIASRSYFNRVINRSRPYMYH
                     IANEVKKRNMPAEAALLPFIESAFVTKAKSHVGASGLWQFMPATGRHYGLEKTPVYDG
                     RHDVYAATDAALNYLQYLYGLFGDWPLAFAAYNWGEGNVGRAINRARAQGLEPTYENL
                     RMPNETRNYVPKLLAVRNIIATPQSFGMNISDIDNKPYFQAVEPDRPLDNEAIARLAG
                     ITQSELLALNPAFNVPAFIPKSKRKLLLPVASVQTFQSNYLNAAPDSLFSWEVYTPAA
                     KTSLSDISTATGMSIADIKRLNNLNGNLVNAGRSILVAKNGKTLQTASESVVSIDIDN
                     TPDTYRSNMPAGTVNVGIARIRPAAAQTADITVAPLPQKTVRTEPDPLVRIAEPALAT
                     AAAQPQTEKQTAMPSETQTATLAQIIPQNDMQAADELMQLVARNNLRRQAEETISAVI
                     GTPDTVAEHNISSSPQHTVAADGKRRARLETRVAKAADGEAEISPLHASIHRVVEGDT
                     LFNIAKRYNVSVADLIVANNIKGNTIQKGQVLRLAQAAPAQTRIEKVSYTARKGDTFK
                     SIAARFNIHIDDIRRLNPNLNTINPGQRVKLIGS"
     gene            22725..23417
                     /locus_tag="ACFOV4_000816"
     CDS             22725..23417
                     /locus_tag="ACFOV4_000816"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFC7618862.1"
                     /translation="MKLIKYLQYQGIGSRKQCQWLIAGGYVFINGTCMDDTDADIDSS
                     SVETLDIDGEAVTVVPEPYFYILLNKPEDYETSHKPKHYRSVFSLFPDNMRNIDMQAV
                     GRLDADTTGVLLITNDGKLNHNLTSPSRKIPKLYEVTLKHPTGETLCETLKNGVLLHD
                     ENETVCAADAVLESPSALLLIITEGKYHQVKRMVAAAGNRVQHLHRRRFAHLETENLK
                     PGEWKFIDCPKL"
     gene            complement(23618..23724)
                     /locus_tag="ACFOV4_000817"
                     /pseudo
     CDS             complement(23618..23724)
                     /locus_tag="ACFOV4_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            24047..25362
                     /locus_tag="ACFOV4_000818"
                     /pseudo
     CDS             24047..25362
                     /locus_tag="ACFOV4_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519747.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            25376..25510
                     /locus_tag="ACFOV4_000819"
     CDS             25376..25510
                     /locus_tag="ACFOV4_000819"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618863.1"
                     /translation="MPSESHTSFRRHCVDARHNTRNARIRTGLPASVGYFRAGGVPSA
                     "
     gene            25606..26262
                     /gene="cmk"
                     /locus_tag="ACFOV4_000820"
     CDS             25606..26262
                     /gene="cmk"
                     /locus_tag="ACFOV4_000820"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFC7618864.1"
                     /translation="MNRQKVIAIDGPGASGKGTVAARVAAALGYDYLDTGALYRLTAL
                     YAQKQGVEWHDEENVSKLAKKLPAVFSGSRILLDGEDVSDGIRTEAIGMGASAVAQLP
                     KVRASLLQRQRDFLTEKGLVADGRDTGSVVFPQAELKIFLTAESKIRAERRAKQIGIP
                     CEGLAFERILSDIEARDEADRNRKVAPLKQQPDALLLDTSRLTIEETVKKVLDWYRKV
                     "
     gene            26417..28102
                     /gene="rpsA"
                     /locus_tag="ACFOV4_000821"
     CDS             26417..28102
                     /gene="rpsA"
                     /locus_tag="ACFOV4_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFC7618865.1"
                     /translation="MSMENFAQLLEESFTLQEMNPGEVITAEVVAIDQNFVTVNAGLK
                     SESLIDVAEFKNAQGEIEVKVGDFVTVTIESVENGFGETKLSREKAKRAADWIALEEA
                     MENGNILSGIINGKVKGGLTVMISSIRAFLPGSLVDVRPVKDTSHFEGKEIEFKVIKL
                     DKKRNNVVVSRRAVLEATLGEERKALLENLQEGSVIKGIVKNITDYGAFVDLGGIDGL
                     LHITDLAWRRVKHPSEVLEVGQEVEAKVLKFDQEKQRVSLGMKQLGEDPWSGLTRRYP
                     QGTRLFGKVSNLTDYGAFVEIEQGIEGLVHVSEMDWTNKNVHPSKVVQLGDEVEVMIL
                     EIDEGRRRISLGMKQCQANPWEEFAANHNKGDKISGAVKSITDFGVFVGLPGGIDGLV
                     HLSDLSWTESGEEAVRKYKKGEEVEAVVLAIDVEKERISLGIKQLEGDPFGNFISVND
                     KGSLVKGSVKSVDAKGAVVALSDEVEGYLPASEFAADRVEDLTTKLKEGDEVEAVIVT
                     VDRKNRSIKLSVKAKDAKESREALNSVNAAANANAGTTSLGDLLKAKLSGEQE"
     gene            28113..28427
                     /locus_tag="ACFOV4_000822"
     CDS             28113..28427
                     /locus_tag="ACFOV4_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003744632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HFC7618866.1"
                     /translation="MTKSELMVRLAEVFAAKNGTHLLAKDVEYSVKVLVDTMTRSLAR
                     GQRIEIRGFGSFDLNHRPARIGRNPKTGERVEVPEKHVPHFKPGKELRERVDLALKEN
                     AN"
     gene            complement(28778..29185)
                     /locus_tag="ACFOV4_000823"
     CDS             complement(28778..29185)
                     /locus_tag="ACFOV4_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFC7618867.1"
                     /translation="MTYTTAKAAEKIGISAHTLRFYDKEGLLPNIGRDEYGNRCFTDN
                     DLQWLGLLQCLKNTGMSLKDIKRFAECTVIGDDTIEERLSLFENQIENVKCQIAELKR
                     YLDLLEYKLAFYQKAKALGSVKAVNLPQIPETA"
BASE COUNT         7455 a         8034 c         6788 g         6931 t
ORIGIN      
        1 atgcaaaaat gccgtccgaa ccgaaacgtg gttcagacgg cattttatag tggtttaaca
       61 aaaatcagga caaggcgacg aagccgcaga cagtacaaat agtacggcaa ggcaaggcaa
      121 cgccgtactg gtttaaattt aatccactat aaaaaacatt acaatcccgg gccgccaagc
      181 gaattggcaa tgtccctgac cgccgttaca tacatccgac tgtgattgta ctgccatacc
      241 gtataaaaat tgttcaagcc caaataatat tcaaacacgc cgggtgcggt ttccagtttg
      301 aacaaaaccg ccttttcatc atctgcaagc tcttcgccgg ggatgatgcc gtacgccttt
      361 aaatccgcca ccgtccgcgt cagggcggtt ttttcgccaa tgattgcctg aacatccgca
      421 cccggcgcca atgttgcaga caccagtatt ttcccgcccg tgcgccaacc gtgctgcttc
      481 atataattgg caaccgatgc cgcgacatcg ccgatgttgc cccatatgtc ccgatgtccg
      541 tccccgtcat aatccaccgc ccatttccgg tagctcgaag gcataaattg cggcatcccc
      601 attgcgcccg catagctgcc tttaaaggcg aaaacatcgc cgccttcttc ttttgccagc
      661 tttaaaagct cgaccaattc tttttggaaa aacccggcgc ggcgggggta atcaaagcct
      721 aaggtcgcca atgcgtccgc cacacggaaa ctgcccgtat ttttgccgta attcgtttca
      781 atcccgataa ccgccacgat aagttcggca ggcacgccgt atttttgcgc cacatcatcg
      841 ataagcgcgc ggttttccgc ataaaaccgg cgcgcgccgc gaaatttcgc cttgcccgaa
      901 tttcccgtgc ggaacacata ccacggacgc gatgtggagg ggcggtgcat aatcttgacg
      961 atgtccgcct tgtaagccgc tttgtcaaaa aaatcctgcc attccgcccg ggaaaaatcc
     1021 cctttcccga cttcatcgtc cacaaaacgg cggacatttg cattggcggc aaacccgctg
     1081 tcggataccg gtacggctgc cgcgtcaaat acggctgccg cgtcaaacgc ggggcggctt
     1141 tcttttttca tttcatccgc gcggggggct tgggcttcat ttgcccgggg cgggcgtgcc
     1201 tccatcgccg tacaggcaga caaagccgcc aaacaaattg ccagcggcag tatttttctc
     1261 tttttcataa atatgttccg aacaaatagg gtaagtggga aagcggcgca agggcgcggc
     1321 gcgaaatgcg gtatccgccg caatcggcgg ctttgcagaa tgccgcgcgt tgccttttgc
     1381 gccgcccgaa atctgcctgc cgccgccgaa aatgccgtct aaaggcactt cccctttcag
     1441 acggcattgc ctgcgccgta tttgcccgct atccgcaata tcggcagtcc aatatgtctt
     1501 tgcggatatc gttcagcagg caggctgccg cgtcttcgtg ttccgcctgt acgaagacaa
     1561 agagtcgggc gatgattttg ccgataaaga ctttttgcag ggcgcaggcg tcggtcagcg
     1621 tgtgttcctg caggaagctg cggatgtctt cgggtaaggt gtaatcacgg gcaacggcgg
     1681 caaagcgggc atcggtttgc aggcggtcga gcagggtttg gtttttgtcc aacttcatgc
     1741 ctgcttcttt ttcttcggcg gtggcgcgga caaactggtc gtaaatttcg gcataaagca
     1801 tatcgttcgg gccttcaaaa atcgtgaagg ggcggatgtc gatagcgata ttgccggcgg
     1861 tgtgtccgcg ttcaaaaccc ttcgcgccca agagtttttg caacatttgc gcggcggcgt
     1921 aagtgtattc cgtggcgagg gttttgacga tgttcgcctc catcagctga tgggcgacgg
     1981 gggcaacagg cgaaacggaa tggcagacgt agcggtaaag aatctcggaa acctgatggc
     2041 ggcgccggat ttcgcggcgt tcgtaatcga cgaatctgat gtcgttgcgg acgtatcgtt
     2101 ccaggttttc aaggatgtat tccataatgc cgtgcgtcat gccgatcagt tgcaggcggc
     2161 tgcggataaa gatgttttgg aacgcgcgca aaccggcagc gtcgctctgg gagagtttca
     2221 tcacggcggt tgcaggcatt tcggcatcga tgcggttgac ggcgtaacgg acggcgcgca
     2281 agccttcgga tgcgagggtt tcgcagcgga tgtatgtttt ggggacgagc agcaggtcga
     2341 tgactttggc gagtttgccg tttttgcgtt ctttggcggc aacgaggagg aagtcgcttt
     2401 gcgagttgcc ctgccagtat tttgcggcgt tgacgtaaat ggtttgtccg tcggtatatt
     2461 cgtagtaaga ctgcatttct cgggcaatcg ccgcgccgga ggtttcgggt tcggtaacgc
     2521 ccaaaccacc gccctcgcct ttgaaaacca tgtccaaacc ctgtgcgatt tgcgcttcat
     2581 cgccgaactc ttgcagtggc tgcaacacca gcgcgccttc gatgccggta cgcagcgtaa
     2641 cgggcacgcc gtaatgcccc gcaatccgca agacttcctg aatttcaaac tggctgccct
     2701 tgcgcccgcc gtgttttttg tcgaggaagg gcaacagcaa acccgcctgc ttcaaggcaa
     2761 gccatttgtc ttcgggcagg tatcgcatca ggtcgatacc gtctgaaaaa atgcggcgga
     2821 atgcggattc gatgtgcttt aaaaaagcag ccgtgtccat agttgacggc tgcgcgctcg
     2881 gttcggtgtg tatcatcggc ttcctctgtc ggttcccatt aatcggcggc cggtcaaacc
     2941 gcctgccaca gtttagagtt gattttctaa actttaccac aaagtgcgcc gggcaacaat
     3001 ccgccgacct ttcagacggc atcgcgcccc ctcccgtgct aaaatgaccg tttgcatcac
     3061 tgtccgccga ttgccgcact atgacctacc ccatccccaa accccgtgaa aaatcccgtt
     3121 ggtccaatct ttcgcaaggc tcgctgccct tggctttggc gcgttatctg ccgcataagc
     3181 ggctcaaggt cgtgctgacc caagatgcgg aacaggcgct acgccttcag acggcatggc
     3241 ggtttttccg tccgcacgac acggcggtgt tcctgccgga ctgggaaacg ctgccttacg
     3301 agcgtttttc gccgcatcag gatttggtgt cggaacggct gtcggcgttg tggcagatta
     3361 agagcggcgc ggcggacgtg ttgttcgtgc cggttgccac ggcgatgcag aagctgccgc
     3421 ccgtgccgtt tctggcaggg cgcacgtttt ggctgaaaac agggcagact ttggatatag
     3481 gccgtctgaa aaccgatttg gtagatgcgg gctacaacca tgtttcccat gttgttgcgg
     3541 cgggcgagtt tgccgtgcgc ggcggcattg tcgatttgtt ccccatgggc agcgaaatgc
     3601 cctatcgcat cgatttgttt gacgatgaaa tcgacagcat caaaaccttt gatacggaca
     3661 cgcagcgcac catctccccc gtttccgaaa tccgcctgct gccggcgcac gagttcccca
     3721 ccgacagcga agcgcaaaaa atcttccgca gccgcttccg agaagaagtc gacggtaatc
     3781 cgaacgatgc ggctgtgtac aaagccgtca gcaacggcca cttcggcgcg ggcgtggaat
     3841 attatctgcc gctgtttttt gaaaatgagc tggaaacgct gtttgactat atcggcgaag
     3901 acgcgctgtt tgtctctttg ggcgatgttc acgccgaggc aaaccgcttt tggagcgatg
     3961 tcaaatcccg ttacgcgatg gcgcagggcg acgaaaccta tccgcctttg cttccacagc
     4021 atttgtatct ctctgctgat gtttttgcag gccgtctgaa aaactacgga caagtgctgc
     4081 ccgatgtttc cggcaaggaa cacgccctcc ccgaccttgc cgtcaaccga caatccgacg
     4141 agcctttgca ggcattgaag gattttcaga cggcgtttga aggacggatt ttgctgtgcg
     4201 ccgaaagttt gggacggcgc gaaaccatgc tcggtttctt gcagcaaaac ggtttgaaag
     4261 ccaaacctgt gtccgactgg cagggcttct tgtcggcgca tgagccgctg atgattacag
     4321 ttgcgccgtt ggcatacggg ttcaaactgg gcggactgca atcgccgaac caacagcaaa
     4381 ctacttccgc ctccgaagga gaaggcgatg cggttaccga ccaaaccgaa ttttccgcat
     4441 ccgcaacaaa ccctctccct agccctctcc cacaggagag ggaacaaagt gcagccgtcg
     4501 tttcagacag tctgaaagca gccgccgttt caaccgaaag ccgcctgccc cccggtaaaa
     4561 gtaatctgca cgggcaaatc caacagcaac ctactccctc ccccgtgggg gagggttggg
     4621 gagagggcaa agcagttgcc gctcaaactg aattttccgc agccgcaata agccctctcc
     4681 ctagccctct ccctagccct ctcccacagg agagggaaca aagtgccgcc gccgtttcag
     4741 acggcctgaa aaccgaaagc agcctgtatt ccatcgcaaa taatctgcac ggacaaatcc
     4801 gacagcaacc taccccctcc cccgtggggg aagattgggg agagagcaaa acagttgccg
     4861 ctcaaaccga atttcccgca tccgcaacaa accctctccc tagccctctc ccacaggaga
     4921 gggaacaaag tgcagccgtc gtttcagaca gtctgaaagc agccgccgtt tcaaccgaaa
     4981 gcagcctgcc ccccggtaaa agtaatctgc acgggcaaat ccaacagcaa cctgccccct
     5041 cccccgtggg ggagggttgg ggagagggca aagcagttgc cgctcaaagt gccatcgccg
     5101 tcatcaccga atccgatctc taccaatacg tcgcccgttc gcgcgcccac aaccgccgca
     5161 agaaacacgc cgccgtttca gacggcctgt tgcgcgacct tgccgaaatc aatatcggcg
     5221 atcccgtcgt gcacgaagaa cacggcatcg ggcggtatat gggcttgatc acaatggatt
     5281 tgggcggcga aaccaacgaa atgatgttgc tcgaatacgc aggcgaagcg cagctttatg
     5341 tgcccgtttc gcaactgcat ttaatcagcc gctactccgg tcaggcgcat gaaaacattg
     5401 ccctgcacaa gctcggcagt ggcgcgtgga acaaggcgaa gcgcaaagcc gccgaaaagg
     5461 cgcgcgatac cgccgccgag ttgcttaacc tttacgcccg acgcgctgcc caatcgggac
     5521 acaagtttga aatcaacgag tcggactatc aggcgtttgc tgatggcttc ggctacgagg
     5581 aaaccgaaga ccaggccgcc gccatcgccg ccgtgattaa agatttgacg caagcgaagc
     5641 cgatggatcg ccttgtgtgc ggcgatgtcg gcttcggcaa aaccgaagtt gccctgcgcg
     5701 ccgcgtttgt ggcggtgatg ggcggcaaac aggtcgccgt actcgccccg accacgcttc
     5761 tggtcgagca gcacgcgcaa aactttgccg accgtttcgc cgatttccct gtgaaagtcg
     5821 ctagcctttc gcgtttcaac aacagcaaag ccactaaagc cgcgctggaa ggcatggcgg
     5881 acggcacggt cgacatcgtt atcggcacgc acaaactggt gcaggacgac atcaaattca
     5941 aaaacttagg tttagtgatt atcgacgaag aacaccgctt cggtgtgcgc caaaaagagc
     6001 agctcaaacg cctgcgtgcc aatgtcgaca tcctcaccat gaccgccacg ccgattccgc
     6061 gtactttaag tatggcgttg gaaggactgc gcgacttctc gctgattacc accgcgccca
     6121 gccgccgcct cgccgtcaaa acctttgtca aaccctttag cgaaggcagc gtgcgcgaag
     6181 ccgtgttgcg cgaactcaaa cgcggaggac aggtattttt cctgcacaat gaagtagata
     6241 cgattgaaaa tatgcgcgag cggctggaaa ccctgctgcc cgaagcccgc atcggcgtgg
     6301 cgcacggaca actgcgcgag cgcgagctgg aacaagtcat gcgcgacttt ttacagcaac
     6361 gattcaacgt gttgctctgt tccaccatca tcgaaaccgg tatcgacatt cccaacgcca
     6421 acaccatcat catcaaccgc gccgacaaat tcggactggc gcaactgcac cagcttcgcg
     6481 ggcgcgtcgg acgcagccac caccaagcct acgcctacct gctcacgccc gaatacatca
     6541 ccaaagacgc agaaaaacgc ctcgacgcca tcgcggcagc agacgaactc ggcgcaggtt
     6601 tcaccctcgc catgcaggat ttggaaatcc gcggcgcagg cgaaatcctc ggcgaagggc
     6661 agtccggcga aatgatacag gtcggcttca cgctctacac cgaaatgctc aaacaagccg
     6721 tgcgcgatct caaaaaaggc cgccaacccg acctcgacgc gccgctgggc atcaccaccg
     6781 aaatcaaact gcacagcccc gccctactgc ccgaaagcta ctgccccgac atccacgagc
     6841 gtctcgtcct ctacaaacgc ctcgccgtct gcgaaaccgt gcagcaaatc aacgccatac
     6901 acgaagaact cgtcgaccgc ttcggcctgc ccgaacaacc cgtcaaaacc cttatcgaaa
     6961 gccaccacct gcggcttatg gcaaaagaat tgggtatcga tgccattgat gcggccggcg
     7021 aagcggtaac ggtaaccttc ggtaaaaaca ataatgtcga tccaaccgaa atcatcctgc
     7081 tgattcagaa cgacaaaaaa taccgccttg ccggcgccga taagctgcgg tttaccgcag
     7141 agatggaaaa tatcgaggtc agaatcaaca ccgtaaaaaa cgttttaaaa accttgcaaa
     7201 acagatgcct gcccaaataa agccgacacc gcaatgccgt ctgaaacacc gttttccttg
     7261 tccgaaagcc gccattatga atttgaagga aactccacta taatacggca ttcagatttc
     7321 cagacggcat cgcgcccgtc agaccgcaca caaaccaaaa ggaaatacat gttccgtact
     7381 atgcttggcg gaaaaatcca ccgcgccacc gtaaccgaag ccgatttgaa ctacgtcggc
     7441 agcattaccg tcgatcaaga tctgttagac gcggcaggca tctaccccaa cgaaaaagtc
     7501 gccatcgtca acaacaacaa cggcgaacgt tttgaaacct ataccatttc aggtaaacgc
     7561 ggcagcggcg tgatttgtct gaacggtgct gcggcaaggc tggtgcagaa aggcgatatc
     7621 gtcatcatca tgtcttacgt ccaactctcc gaacccgaaa tcgccgcgca tgaacccaaa
     7681 gtcgtcttgg tagacggaaa caacaaaatc cgcgacatca tctcctacga gccgccgcac
     7741 accgtgctgt aaccctgaaa acggacattg atcatggata ttaaaattaa cggcattacc
     7801 gtcggtaacg atgctccttt cgtactgttc ggcggcatca acgttttaga agatttggat
     7861 tccaccctcc aaacctgtac gcattacgtc gaagttaccc gaaaactcgg tattccctat
     7921 atctttaaag catctttcga caaggcaaac cgttcctcca tccattctta tcgcggcgta
     7981 ggcttggaag aaggcttaaa gatttttgaa aaagtcaaag cggaattcgg catccccgtc
     8041 attaccgacg tacacgaacc ctatcagtgc caacccgtcg ccgaagtgtg cgatgtcatc
     8101 cagcttcccg cattccttgc gcggcagacc gatttagtgg ttgccatggc aaaaaccggc
     8161 aacgtcgtca acatcaaaaa acctcagttc ctcagcccct ctcaaatgaa aaacattgtg
     8221 gaaaaattcc acgaagccga caacgggaaa ctgattttat gcgaacgcgg cagcagcttc
     8281 ggctacgaca acctcgttgt cgatatactc ggtttcggcg tgatgaaaca gacttgcggc
     8341 aacctgccgg ttattttcga cgttacccat tccctgcaaa cccgcgatgc cggttctgcc
     8401 gcatccggcg gtcgtcgcgc acaggctttg gatttggcac ttgcaggcat ggcaacccgc
     8461 cttgccggtc tgttcctcga atcgcacccc gatccgaaac tggcaaaatg cgacggcccc
     8521 agcgcgctgc cgctgcacct tttagaagat tttttaatcc gcatcaaagc attggacgat
     8581 ttaatcaaat cacaaccgat tttaacaatc gagtaacacg gtttcgcctt atgatgcaga
     8641 ctttccgaaa aatcagccgg tatgtcgcaa ccttgtggct cggtatgcag attatggcgg
     8701 gttatatcgc cgcaccggtg ctgttcaaaa tgctgcccaa aatgcaggcg ggcgaaattg
     8761 ccggcgtatt gttcgacatc ctctcttgga gcgggcttgc cgtttggggc gcggtgttgg
     8821 ctgccgcctt tgccatcctg acccgactgc aaaccgccct gctgcttttt ttattgtccg
     8881 cccttgccgc caaccaattt ttggttaccc ccgttatcga ggcactgaaa tacgggcatg
     8941 aaaattggct gttgtcgttt gtaggcggat ccttcggaat gtggcacggt atttccagca
     9001 tgattttcat ggcaaccgcc ctactttcag cagttttaag ttggcggctt tccggcaaag
     9061 atgccgtctg aagccctccc atttttttac ctcccttcac ttcacttgga gaacattcat
     9121 gagcgcaatc gttgatattt tcgcccgcga aattttggac tcacgcggca accccacagt
     9181 cgagtgtgat gtattgctcg aatccggcgt aatgggacgc gcagccgtac cgagcggcgc
     9241 gtccaccggt caaaaagagg ctttggaact tcgcgacggc gacaaatccc gttattcggg
     9301 caagggcgta ttgaaggcgg tcgaacacgt caacaaccaa atcgcccaag ccctcattgg
     9361 tatcgatgcc aacgagcaat cttatatcga ccaaatcatg atcgaattgg acggtactga
     9421 aaacaaaggc aatttgggtg cgaatgcgac tttggcggtt tctatggcgg ttgcacgcgc
     9481 cgctgccgaa gactcaggcc tgccgcttta ccgctacttg ggcggcgcag gcccgatgtc
     9541 cctgcccgta ccgatgatga acgtcatcaa cggcggcgaa cacgccaaca acagcctgaa
     9601 catccaagag tttatgatta tgcccgtcgg cgcaaaatct ttccgcgaag cgttgcgctg
     9661 cggtgcggaa attttccacg ccttgaaaaa actgtgcgac agcaaaggct tcccgaccac
     9721 agtcggcgac gaaggcggtt tcgcccccaa cctgaacagc cacaaagaag ccctgcaact
     9781 gatggtcgag gcgaccgaag ccgccggcta caaagcgggc gaagacgtat tattcgcatt
     9841 ggactgcgcc tccagcgagt tctacaaaga cggcaaatac cacttggaag ccgaaggccg
     9901 ctcctacacc aacgcggaat ttgccgaata tctggaaagt ctggtcaacg agttccccat
     9961 catctccatc gaagacggca tggatgaaaa cgactgggaa ggctggaaac tgctgaccga
    10021 aaaactgggc ggcaaagtcc aactcgttgg cgacgacctc ttcgttacca acccgaaaat
    10081 ccttgccgaa ggcattgaaa aaggcgtggc aaacgcacta ttggtcaaag tcaaccaaat
    10141 cggtactttg agtgaaaccc tgaaagccgt cgatctggca aaacgcaacc gctacgccag
    10201 cgtgatgagc caccgctccg gcgaaaccga agacagcacc attgccgact tggcagtcgc
    10261 caccaactgt atgcagatca aaaccggttc tttgagccgt tccgaccgca tggcgaaata
    10321 caaccaactg ctgcgtatcg aggaagaatt ggcggaagcc gccgactacc ccggcaaagc
    10381 cgcattctac caactgggca aataaaaaag gttaaggtat gaagtgggta actgtcgttt
    10441 tatccttcgc acttgtctgt tgccaataca gcctctggtt cggcaaaggc agcatcggac
    10501 gcaacagcag tctgagagaa cagattgccg ttcaagaaga aaaaaaccag acactcgccc
    10561 tacgcaatca ttcccttgcc gccgaagtct atgatttgga aaacggtcaa gaagccattt
    10621 cggaaatcgc ccgggtagaa ctgggttata tccaagacgg tgaaaccttt taccgactca
    10681 tcaggcataa ccggtaatac cgtcaaaaag ccgtccgaac caatgttcgg acggctttta
    10741 tttcaacaaa ctgtcagaca gcccctcatc ctcccccgac aaaccgcaat ccagcctgac
    10801 atccccctcg acgcaacagc agcacggcag tatctcgtcc cgccccaaaa aagccaaagg
    10861 cggctcccga taagtaacgc ttccctccaa aatcttcact cggcacgatc cgcaatatcc
    10921 gcttcggcac tgatattcca ccatatgccc cgtccgttcc aagccttcca acagggtctc
    10981 gccctccaag agctcaaaaa aacccttatt cgtaccaatg cgcgccattt ccgaccaatc
    11041 aaaaatatag tggattaaat ttaaaccagt acggcgttgc ctcgccttgt ccggattttt
    11101 gttaatccac tataatccac tataaaagga acaataaccg atcctacccg ctgtttttcc
    11161 catcatacaa catacaaatg ccgtctgaaa catccggctt cagacggcat tttttcaaaa
    11221 aacatttaca actcaaaatc gcccaaatca tccgtattca cttcagaatc tatctgaccg
    11281 atcaaataag aggatatttc cacttcctgc ggcgcgacct gtacgttgtc ggacgacagc
    11341 cacgcattaa tccacggaat cgggttttga tttgcgcctt caaatccggc cggcaacccc
    11401 accgcctgca tacgcagatt ggtaatatat tcgacgtatt gggataagat ttctttgttc
    11461 aaaccgatca tcgaaccgtc cttaaacaaa tatgccgccc attctttttc ctgttccgcc
    11521 gcttttttga agagttggaa acattcgtcc tgcaactcgg cggcaatttc cgccatttca
    11581 gaatcatcaa caccagaacg catcagatta agcatatgct gcgtgccggt caggtgcagg
    11641 gcttcgtcgc gggcaatcag tttgatgatt ttggcgttgc cttccatcaa ctcgcgctcg
    11701 gcaaaagcaa acgagcaggc gaatgaaacg tagaaacgga tggcttccaa cacattgacg
    11761 cacatcaggc agagatagag ttttttcttc aacccgcgca aagacacggt aacgggtttg
    11821 ccgccgacat tgtgcacccc ttcgcccaac aggttgtaat actgggtgta ttcgattaag
    11881 tcatcgtaat agcaggcaat gtcttcggcg cgggcggtaa tgtattcgtt ttcgacaata
    11941 tcatcaaaca cgaccgacgg atcattcaca atattgcgga tgatgtgggt atagctgcgc
    12001 gagtggatgg tttcgctgaa gctccacgtt tcaatccacg tttccaactc gggaatcgaa
    12061 accaaaggca gcaaagcaac attcggactg cgcccttgga tggaatcgag cagtgtttgg
    12121 tatttcagat tgctgatgaa aatatgtttt tcgtgttctg gcaggttggc gtagtcgata
    12181 cggtcgcgcg acacgtcgat ttcttccggc cgccaaaaaa acgacaattg tttttcaatc
    12241 agtttttcaa atacctcgta tttctgctgg tcataacggg cgacattaac cggctgaccg
    12301 aaaaacatcg gctcattcag cgcgtcgttt ttggttttgg gaaaggtgct gtatgacata
    12361 gttaagtgtt cgcaggacat aatctattct ctatattaat taaaaatgat ctgtaagttt
    12421 taactaacct gctgagactt tatatattta ataaaatttt ctaaagttaa aacatgggtt
    12481 ttcccaaaag ttccaaatgt ttttacggat tctttaggga caactaaggt taaattctca
    12541 tcactcattt cctgaatttg agtatcagat ataccttctt gtagagtaaa taaatgctta
    12601 tgaggaattc gatctgcttc atttaaaact tggcgccagc gatccttaca agtagtcttt
    12661 gaacctagca ttgtcagctt ttcagtttga aatatgaaat tccctgattc atccatcgca
    12721 tggtactctt cacttccagg aaataaaaaa tctggtttct ttttcccttc tgtcttcgct
    12781 tgcgtctcaa attttaagga aaattcgtca aatattcttg ataaatgtaa ctctaaagat
    12841 tttcctgctc ttgcttttct gcgatttgta aaagaatgtg caaaattaat gaagctatcc
    12901 aaatcagtaa tttttgattt aataatttca aattcacgtt tttcaaaaat ggaaaataat
    12961 tcatattcct ttgaaaccca ttgttttaac acattactaa cgttagtttt atttaatgca
    13021 atattttccc ttgccaaaac tgccatttct tcagttttgg ggaagttagg aaatagtgaa
    13081 aataattttg ttaggttatc ctctacttct tgttttttag gtaaatataa acttcctggt
    13141 aaaatgttag tttctgcgat aaatatttca atatcttcat ctgaagataa aacaaaagca
    13201 tggaataata aatctttata acaagctctg cacaatacca ataaggaacc actatattta
    13261 tcacttaaaa attcaaaatt cttgccaaaa cccgtaattc tcgcctcatt tctcgtgcct
    13321 tggccgtaat atttaaaatt gctattagtg acgcttccat cttgccaatt aattttgatt
    13381 gaaatagttt tatttgttcc cttttggcaa actacatcaa agaggtcgtc tgaaaaatgt
    13441 ttttgaatat aaaatcctga ttggtgacta ccagtagtac caacatcatt gggacgaata
    13501 taacgacagt atactgcaat tgatttattt gctgtctgta ttgctgaagc tactaagtca
    13561 tcggatttat ttactacttg tattgtctga gctgccaagt cattcatttt tttaactcat
    13621 ttataatttg tttagcaata gcttgaacca acggtacagc aattgaattg ccaaactgct
    13681 tgtatgcagc tgtcttggat actgcatcaa taacaaaatc tttaggaaat cccattaaac
    13741 gcgagcactc cctaggtgtc agcttcctag gattttttcc tttctgaggg atgagtattt
    13801 cggaaccatc tttgtaatat cgtgcagata gagttcgtga tattccatct aaatcaacta
    13861 atccaaaacc aaatccatta ccctttgcct tatgtttttt agcgtaattt tgaaggtaaa
    13921 gccataagtt atcagaaaga gtaaaagaat tatctacatc atcttccaaa atttgcttta
    13981 attttggttg tgattctggt ggggaaggaa aattgaaatt tatttcctta ttaaaatatt
    14041 gtctatcaaa acctacaata aaaatacgct ccctattttg aggaacataa tattttgcat
    14101 tcataacttg ataaaatatc tgatagtcaa gctcttctaa agtcccttta attactttaa
    14161 atgtatttcc tttgtcatgc gaaacaaggt ttttcacatt ctctaaaaga aaaattttag
    14221 gtcgatgttt tccaataatt tcagcaacat caaaaaatag agttccctgc gccttatcta
    14281 agaagcctgt ttctcgtcct aggctttttt tctttgaaac accagctata gagaatggct
    14341 gacacgggaa tcctgctgtt aatacatcaa acttacttgg aatagctgct ttggtttcct
    14401 ttaatgtaat atctccataa ggaatatcat taaaatttac ttggtaggtt tgacgggctt
    14461 tatcatccca ttcactagaa aatacacatc gcccaccaac attctccatt gcaatgcgaa
    14521 aaccacctat tcccgcaaat aaatcaataa aagtaaattt ctcattattt aaggtaacta
    14581 tattatctaa ttgattttgt attttatttt tcatatttta tatttcagat gatttattaa
    14641 tctaaaggcc atctgaaaac tccccctttc atcaaatctt acaagccccg cccgcgcagc
    14701 cgtcatcctg aatatcggtc tgcgtatcgt ccgcaccgtc gcgggtgtta tggtagtaca
    14761 gggttttgac gccgtatttg taggcggtca gcaggtcttt gagcatttgt ttcatagaaa
    14821 ctttgccgcc ttcgaatttg cccgggtcgt aggcggtatt ggcggaaatc gattgatcga
    14881 cgaatttttg catcacgccg acaagtttca ggtagccttc gttgccggga agctgccaca
    14941 gggtttcata ggcatttttc agggtttcaa actccggcac gacttgtttc aaaatgccgt
    15001 ctttcgatgc tttgaccgtt accaatccgc gcggcggctc gatgccgttg gtggcgttgg
    15061 cgatttgaga gctggtttca gacggcatga gcgcggtcag agtagagttg cgcaggccgt
    15121 atttgacgat ttcggcacgc aggctttccc agtcgtaatg caaaggctcg ccgcagacgg
    15181 catccaaatc ttttttgtag gtgtcgatgg gcagtttgcc ttgcgaataa acggtttggt
    15241 taaagagcgt acacgcaccg tattctttgg caaggtttgc cgatgctttg agcaggtaat
    15301 actgtatggc ttcaaaggta cggtgggtca gaccgagcgc ggagccgtcg ctgtagcgga
    15361 caccgttttt cgccagataa taagcatagt taatcacgcc gataccgagc gaacggcggc
    15421 ccatagtgga ggtacgcgcg gcttctaccg gatatccctg ataatctaaa agtgcatcga
    15481 gtgcgcgcac agtcaaatcg gcaagccctt ccaattcgtc caggctgttt aatgcgccca
    15541 agttgaaggc ggacagggta cacagggcga tttcgccgtt cggatcgttg atattgtcca
    15601 gcggtttggt cggcagggcg atttccatac acaagttgga ctgatgaaca ggcgcgacgc
    15661 gcggatcgaa cgggctgtgc gtattgcagt gatcgacgtt ttgaatgtag atgcgcccgg
    15721 ttccggcacg ctcctgcatc agcgtggaaa acaggtcggc agccggaatg atgcgcttgc
    15781 ggatatcagg gtcttgctcg tatttcgtat agagccgctc aaattcgtct tggtcggcaa
    15841 aaaacgcttc gtacaatccc ggaacctcgt tgggcgaaaa cagcgtaatg ttgccgccct
    15901 taatcaggcg ggtgtacagt aggcggttga tttgcacacc gtaatcaagc tggcggatac
    15961 ggttgtcttc cacgccccgg ttgtttttca acaccagcag gctttcggct tcgatatgcc
    16021 acaaggggta gaacaaggtt gccgcgccgc cgcgcacgcc gccttgcgaa caggatttga
    16081 ccgccgcctg aaacattttg aaaaacggga tgcagccggt atgccgcgct tcgccgcccc
    16141 ggatttcgct gtccaaaccg cggatacgtc cggcattgat gccgatgccc gcacgctggg
    16201 aaacgtattt cacaatcgcg ctggtagtgg cattgatgga atccaaacta tcgtcgcatt
    16261 caatcagcac acagcttgag aactggcgcg taggcgtacg cacgccgctc ataatcgggg
    16321 tcggcagcga tactttaaat gtggaaacgg catcgtaaaa ccgtttgacg taatcgaggc
    16381 gtgtttcttt gggatatttg ctgaaaagac acatcgccac cagaacatat aagaactgcg
    16441 gtgtttcata aatctggcgg gtaacgcggt tctgtaccag atatttgcct tcgagctgtt
    16501 tgacagcggc ataggaaaag gacatatcgc gttcgtggtc gatataggcg ttcagctcgt
    16561 caaattcttc gcggctgtaa tcctcaagga tatgcctgtc gtattttgcg gcatcggtaa
    16621 gttttttaac gtggtcgtaa aggtgcggcg gctcgtactc gccgtaggct attttacgca
    16681 gatggaaaat cgccaaacgc gcggcaaggt attggtagtc cggggtatct tccgaaatta
    16741 aatcggcagc ggctttgatg atggtttcgt ggatgtcgtc ggtgcggatg ccgttgtaga
    16801 actggatgtg cgatttcaac tcgacctgag atacggaaac attttccaat ccgtccgccg
    16861 cccaagtgac gacacggtga atcttatcca aatcaatggc ttctaatctt ccgtctcgtt
    16921 tggttacttt caaatcagtc ggtgtattca tcgcttcctc ttccactctt gatattcaag
    16981 acacggtctt ttcaaataaa ttaaggcaga caatatagtg gatttttggc attttctcca
    17041 gtcttgacaa cggttgtatt tttcagtttc aggcaatgcg cgataaaacc cgcctgtcgt
    17101 atttttccta taatatttgt tttatctgat aattctttac cgataaaaaa cgggtaaatt
    17161 ttttgccttt tgaccggctc cggctacaag gcggtgaaat aaggattttc cgacgaaaaa
    17221 ggaaagcttc ctgttttctg cccctgcaaa ttgttaaatt ttgcaaagta tgattttgcc
    17281 gcgccgccgc cgacaaattc cattttctta ccgattggaa tttattattg agattaatgt
    17341 gttatttgaa tctgcatatc aaacggcaag ttttgtcggc tgaatgagtc tgaaactgcc
    17401 gacaatttgc ccgctccatc cttccatcct atactggaag gaatgacaaa ctgaaaggat
    17461 cgtcatgtct gtcaaaaaga tgcttgccat actgttgtct gcaatattgg gactggtatc
    17521 gacaactgcc gctgccggta cgtcagaacc cgcccaccgc gataccaaac atatccgcaa
    17581 ggcaaacaag cagatgctgc accccgaatg caggaaatat ttggaacgcc gtgccgcgtg
    17641 gtaccgatcg caaggcaacg tgcaggaatt gcgcgaaaac aaaaaggcgc gcaaagcatt
    17701 ccactccctg ccttatgcgg aacagaaaat ccaatgccgg gcggcttatg aggctttcga
    17761 tgatttcgac ggcggcagtt tccgccgtta atcccatata aaatatgccg tctgaacaca
    17821 ggttcagacg gcattttcca tagatacaac aaactatcct tacgccattt cgtttgaggt
    17881 cctcccgttg ccgcagcctt aatatagtgg attaacaaaa atcaggacaa ggcgacgaag
    17941 ccgcagacag tacagatagt acgaaaccga ttcacttggt gcttcagcac cttagagaat
    18001 cgttctcttt gagctaaggc gaggcaacgc tgtactggtt taaatttaat ccactataca
    18061 tccacaaaag cgaatcatac tgccacattc cgacaaccgg tttcagacag cgatatccgc
    18121 atcgtcggcg acaacggcac ggatgctttc ttcgatttta tcttttaaag cataacggtc
    18181 ttcgctttcc gccgcatccg ccacgcaaac gaaatcgact tttatcgtca attttttcat
    18241 agacacgatg cgccacaggc aggtcggcaa accgacatcg gcatatgagg gacgagccgt
    18301 cctttttccc gtttcgtcat aataacgcag cgcgaccgcc aaaacctttg cccccgcatc
    18361 gatggcggat tggaacagcg cggctttgaa cggcaaaagc cccaatccgg aggaagtccg
    18421 cgcttcgggg aaaaaactga cgttttgacc gcgttgcaag gtttcgcaga cggcgcggtt
    18481 aatcggttcg atgtcgcgcc gcgaattgcg gttgatgaac accgttcccg cgttctgccc
    18541 catcttgccc aataccggcc agcttttgat ttcctgcttg gcgataaagc tgctcggata
    18601 aaccgcgctc atcgcgaaaa tatccagcca ggacacgtgg ttggcggcaa ccaagacacc
    18661 gttcggatgt tcgggtgcgg gtctgcccac ctccaatccg atatccaaag ccgccaaaac
    18721 ccccctgccc aactcgatta ccgcccgatt gcgcgactcg gggcaaccgc cgtcaatacc
    18781 gcgcaggttt ttcccggttt tgaacagcca gaccgccaaa cggcacaagc ggcgcagacg
    18841 tgtaaaaaat gaagctttat ttgaagacat gagcaattct ttcccgataa tcggtgtttg
    18901 ttgttgaaac gttcggacgg cataccgata aaatgccgtc tgaaaccgtt ttcagtccta
    18961 tttctgacag ttcgggcaat aaaacgtgcc gcgctgcccc aaagtttctt tcacaaccaa
    19021 accgccgcac tgggggcacg gctgattgtg ccgcccgtac accgtatatt cctgttggaa
    19081 gtagccgctt ttgccgtcgc tgtccacaaa atccctcaag gtactgccgc ccgtttcaat
    19141 ggcgcgccgc aacaccgctt tgacggtttc aaccaaaagc gcgcactctt tctttttcag
    19201 gcggttggca ggacggtagg gcgaaatgcc cgccctaaac aggctctcgt tggcataaat
    19261 gttgcccaca ccgaccacga ccgcattgtc catcagggca agtttgaccg cgcgcttctg
    19321 cgccttcagc cttgcataca gataatccgc acaaaatgcc tccgacaaag gctccggccc
    19381 cagtttttcc aacagcggat gatgttcttc gattccctca taccaaagta tcgcgccgaa
    19441 ctttctcgga tcgcggtaac gcatgaccgt gccgtctgaa aacacaatat cgacgtgatc
    19501 gtgtctgtcc ggcctgccga tacgtccgtc cgacggcgta aaaatccgca agctgcccga
    19561 catccccaag tgaatcagca gcacgcccgt ttgaaagcgg ataagcaggt atttcgccct
    19621 cctgccgcag gacaacacct gccggccgga caaaatctcc cccaaatcgg gattaatctg
    19681 ccagcgcagc ttcaattggc gcaataccac ggcttccacc gttttccctt caatatgcgg
    19741 cgcgatgccg cgcaacgtcg tttccacttc cggcaattca ggcataaccc ctcccgacat
    19801 tttttctgac agatgccgtc tgaaagacgg ccgtccctaa tccgcaaccc ttgccgcacc
    19861 cgccgcaagg gctttgccgc ccaaataccc gtcccacgcg ggcaggggcg ttacgcccgc
    19921 cgcccttttg accaaaacca aagcgtacac tgcggcacat tgcggccacc aacggtcgcc
    19981 cgccttttcc ataaaccgcc aaaagcgtat ttgcccgagc gacgaaaccg gcggcagata
    20041 caccataaat ttcccaaatt caatatcgaa accggcatcg gcaagccgcc ttttcaactc
    20101 gggcagcggc agacaaaacc gtttttccgg caggcgttcg ccgtcaaacc aacggctgaa
    20161 tccccagagc gaatacggat tgaaacccgt cagcatcaag cgtccgcacg gtttcaatat
    20221 ccggtgcgct tccgacagga tttgcgaagg aacaccgcct tcaagcgtat gcggaaaaag
    20281 cagcatatcc gcagaaacat ccgccaaagc catattctcc gccgacatcg acatatctcg
    20341 cggcacacag acaacatctt cagacaggct cagccacctg ccgcccacct gaaccgcaca
    20401 cattcccgaa aaacggtatg aatccagata ccgcccgaag aaatcctgtt ccaattttgc
    20461 aacataccgc cccatcgccg tatcttcaaa ccatgcatcc atattgcgtc cgtttcaaac
    20521 agattgcctg ccgatattct attccaaaca ggatttctgt caaaaaacac atcggccgcc
    20581 catttccgaa tccgcataaa gttcctgtaa aacttgacgc tttttcagtc aaacagtacc
    20641 atcggacgat aaaatatgtt tattccgccg aatataaatc atgtccaaac tcaaaaccat
    20701 cgctctgacc gcatcaggtc tgtccgtttg tccgggtttc ctatacgccc aaaacacctc
    20761 atcacaccaa atcggtttgg cgattatgcg cttaaactct tcaatactcg acctgccccc
    20821 gacaaaacaa tatttccaat ccggcagcct gtggagcgag ctgcgccaag gcttccggat
    20881 gggcgaagtc aatcccgaac tggtacgccg ccacgaaagc aaattcatcg caagccgcag
    20941 ctatttcaac agggtcatca accggagtag accctatatg taccatatcg ccaacgaagt
    21001 caaaaaacgc aatatgcccg ccgaagccgc cctgcttccc ttcatcgaaa gcgcgttcgt
    21061 caccaaagcc aaatcacacg tcggcgcatc aggattatgg cagtttatgc ccgctaccgg
    21121 caggcattac ggcctggaaa aaacaccggt ttacgacggc aggcacgacg tttacgccgc
    21181 caccgatgcc gcactcaact atctgcaata cctctatgga ctgttcggcg actggccgct
    21241 tgcctttgcc gcctacaact ggggtgaagg caacgtcgga cgcgccatca accgcgcccg
    21301 cgcccaaggg ctcgaaccga cctacgaaaa cctgcgtatg cccaacgaaa cgcgcaacta
    21361 tgtccccaag ctgctcgccg tgcgcaacat tattgccact ccccaatctt tcggcatgaa
    21421 tatcagcgac atagacaaca aaccctattt tcaggcagtc gaaccggatc gtccgctcga
    21481 caacgaagcc atcgcccggc ttgccggcat cacgcaaagc gagctgctcg ccctaaaccc
    21541 cgcattcaac gtccccgcgt ttatccccaa aagcaaacgc aaactgctgc ttcctgtcgc
    21601 gtccgtacaa accttccaaa gcaactacct caacgccgca cccgacagcc tgttttcatg
    21661 ggaagtctat acgcctgccg ccaaaaccag cctgtccgac atctcgacgg caaccggcat
    21721 gagcattgcc gacatcaaac gcctcaacaa cctgaacggc aaccttgtca acgcaggacg
    21781 cagcatcctt gtcgccaaga acggcaaaac ccttcagacg gcatcggaat ccgtcgtttc
    21841 catcgacatc gacaatacac ccgacaccta ccgttccaat atgccggcag gcacggtgaa
    21901 cgtcggcatt gcccgaatcc gacccgccgc cgcacagaca gcggacatta ccgtcgcacc
    21961 tttgccgcag aaaaccgtcc gtacggaacc cgatcccctt gtccgtattg ccgaacctgc
    22021 ccttgcgaca gccgcagcgc aacctcaaac cgaaaaacag accgccatgc cgtctgaaac
    22081 ccaaaccgca acactcgcgc agatcatccc ccaaaacgac atgcaggcgg cagacgaact
    22141 catgcagctt gttgcccgaa acaacctgcg ccgacaggct gaagaaacca tctccgccgt
    22201 catcggcacg cctgacacag ttgccgaaca caacatttcc tcatctccgc aacataccgt
    22261 tgccgccgac ggcaaacgcc gggcacgttt ggaaacgcgc gtagccaaag ctgccgacgg
    22321 cgaagccgaa atctccccgc tccatgccag catccaccgc gttgtagaag gcgacaccct
    22381 gttcaacatt gccaaacgct acaacgtcag cgtagccgac ctgattgtcg ccaacaacat
    22441 caaaggcaac accatccaaa aaggacaggt actccgcctg gcgcaggcag cccctgccca
    22501 aacccgtatt gaaaaagtat cctacaccgc gcgcaaaggc gacaccttca aaagtatcgc
    22561 cgcgcgcttc aatatccata tcgacgacat ccgccggctc aatcccaacc tgaacaccat
    22621 caatccggga cagagggtca aactgattgg aagctgattc ggatacggca catgacagga
    22681 ctttctcagt cctgtctttt tcatcccaca tttcccatac catcatgaaa ctcatcaaat
    22741 acctgcaata tcaaggcata ggaagccgca agcagtgcca atggctgatt gccggcggtt
    22801 atgttttcat caacggaacc tgtatggacg acaccgatgc agacatcgat tcctcatctg
    22861 tcgaaacgtt ggatattgac ggggaagcag taaccgtcgt tcccgaaccc tatttctaca
    22921 tcctgctcaa caagcccgaa gattacgaaa cttcgcacaa accgaaacac taccgcagcg
    22981 tattcagcct gttccccgac aatatgcgga acatcgatat gcaggcggtc ggcaggctgg
    23041 atgcggatac gaccggcgta ttgctgatta ccaacgacgg caaactgaac cacaacctga
    23101 cttcgccgag cagaaaaatt cccaagctat acgaagtaac gctcaaacac cccacaggag
    23161 aaacgctctg cgaaaccctg aaaaacggtg tcctgctcca cgacgaaaac gaaacggttt
    23221 gcgccgccga tgccgtgttg gaaagcccgt ccgcattgct cctgatcatt accgaaggca
    23281 aataccacca agtcaaacgg atggtcgccg ccgcaggcaa ccgcgtgcag catcttcacc
    23341 gccggcgatt cgcacatttg gaaacagaaa acctgaaacc cggcgaatgg aaatttatcg
    23401 attgtccgaa actctaaaat aacatccaag aattccattt atattcatcc acatactcat
    23461 taaatatatg gtttaaccca atttaacgca aaaaatcaat ttacgatata atccatttgt
    23521 ctgagtaacg cctgttcaag caggcttatg agtaagacgt tttccccgta atgtgttttg
    23581 ccatctatac ttctcccctt gtatagatgg ttttttatag tggattaaat ttaaaccagt
    23641 acagccttgc ctcgccttgc cgtactattt gtactgtctg cggcttcgtc gccttgtcct
    23701 gatttttgtt aatccactat atttcaaatt ccctctcttt catcattatt taaatgctat
    23761 cattaatata attaacaaaa tttcatttcc atacaccgat gtagaagaat aacaaattaa
    23821 tctatttata aactccgatt cttcctcatc gggttatact catcagaaat actcactgaa
    23881 atatatgcct tttacatgga aaatcactag acagttgaaa aacaattagt cagttcctgt
    23941 taaaaaacgc gtgtagaatt tccgctttat ctcaatcgga cacggtttca atatgtcttc
    24001 cccttcaaat accaatcgtc aaacctgatc cagccgatta acctatatcc tgaccgttgc
    24061 cggcgcgact gtcggcttcg gcgcgacgtg gcgttttccc taccttgtcg gcgaaaacgg
    24121 cggcggcgcg tatgtgtttt tattctgtat cgcgatgctg gttatcggca tcccgatgat
    24181 tttggtggaa aatgtcatcg gacggcgcaa aggcgtgaac gcgctggatg cgttcggcgg
    24241 cccgatgaac ggcaaaccca ttgccaaaat ttggaaactg gtcggctgga tgggctgctc
    24301 ggcgcgttcg gcatcatggc ttattacatg gtgctcggcg gctgggttat cagctacatt
    24361 gttaatatca tcggcggtaa tttggacatt tccagtcctg tttccagcga agtcaccaaa
    24421 agtttcttta ccgaacacat cgaaaacagt ccttgggaaa ttgctttcta caccttccta
    24481 tttgtggttg tgaaccaatg gatcttggta aaaggcgtga tcggcggtat tgaaaaagcg
    24541 gcaaaatacc tgatgccttt gctgttttta ttcctgattg ccatggttgt gcgcaacgtt
    24601 accctgccgg gcgcaatgga aggcattacc ttctatctga aacctgactt cagcaaaatt
    24661 acagccgaac tgttcgtctt cgttttagga caagtgttct ttaccttgag cttgggtttc
    24721 ggcgtgatga ttaccttgtc cagctatctg gataagaacg aaaatctggt gcaaaccgcg
    24781 gtcatcacgg ccattaccaa taccatcatc gccgtactgg ccggctttat gattttcccg
    24841 tcgctcttca gcttcggcgt cgcgcccaat tctggcccga ctttggtatt ccaaagtttg
    24901 ccgattgtgt tctcacatat gtgggcagga cctgtgttcg ctgtcatttt cttctctctg
    24961 ctcctgattg ccgcgctgac aacttcgctg acgatttatg aagtgttgat tacgaccatt
    25021 caggaaaaaa ccaaaatccg ccgtaccgcc gcaatcacga ttgtattgtc cgccatcttc
    25081 atcttcggca atattccgtc cattctgagc tatggcccgt ggaaagatgt ttccatattt
    25141 ggcaaaaata tttttgacgc ttttgactac atcagcggca acatcttgtt tatgctgacc
    25201 gcgctcggct ccgcgctgtt tgtcggtttt gtgatgaagg atgaagcgaa ggacgaattg
    25261 ctttataaag gcaaccatat aacggtcaat atttggtttg cctatgtgaa ataccttgtg
    25321 ccgctggtga ttttgctgat tttcgtcagc aacctgttct aatccgcagc aatcgatgcc
    25381 gtctgaaagt catacctctt tcagacggca ttgcgttgat gcccgccaca atacccgcaa
    25441 cgccagaatc cgaaccggct tgccggcttc tgtcggatat ttccgggcag gcggcgttcc
    25501 gtctgcttag acaatcgtcc tttaaaacag gtagaatctg ccccaacggg aaacacatcc
    25561 ttcagacggc aaaacccata ccccaaacca tcaggaatcc cccttatgaa cagacaaaaa
    25621 gtcatcgcca tcgacggccc gggcgcatcg ggcaaaggca cggttgccgc ccgcgttgcc
    25681 gccgcattgg gatacgatta tctcgatacc ggcgcactct accgcctgac cgccctatat
    25741 gcacaaaaac aaggcgtgga atggcacgat gaagaaaacg tttccaaact ggcaaaaaaa
    25801 ctgcccgccg tattttcagg cagccgcatc ctgctcgacg gcgaagacgt ttcagacggc
    25861 atccggacag aagccatcgg catgggcgca tccgcagtcg cacagttgcc taaagtccgc
    25921 gcctccctgc tgcaacgcca acgcgatttt ctgaccgaaa aaggactggt cgccgacgga
    25981 cgggacaccg gatcggtcgt cttcccccag gccgaactca aaatttttct gacagccgaa
    26041 tccaaaatca gggccgaacg ccgcgccaaa caaatcggca tcccctgcga aggtttggca
    26101 ttcgagcgca tcctgtccga catcgaagcc agagacgagg cagaccgaaa ccgcaaggtt
    26161 gcccccctga aacaacaacc cgatgccctg cttttggata cgagccgcct gactatagaa
    26221 gaaactgtaa aaaaagtgct tgattggtat cgtaaagttt aaattttcag gtataatcgc
    26281 ccgcattgcg tttcagacag catgaatttc cccatatgcc gtctgaaacc ttatttaccc
    26341 gtctgccctg ccaaggacgg cagacaccca ccaacccacc ccgcacccct tggcggtgta
    26401 ccgaaaagag ttatatatgt ctatggaaaa ttttgctcag ctgttggaag aaagctttac
    26461 cctgcaagaa atgaacccgg gtgaggtgat taccgctgaa gtagtggcaa tcgaccaaaa
    26521 cttcgttacc gtaaacgcag gtctgaaatc agaatccctg attgatgtag ctgaattcaa
    26581 aaacgctcaa ggcgaaattg aagttaaagt cggcgacttc gttaccgtta ccatcgaatc
    26641 cgtcgaaaac ggcttcggcg aaaccaaact gtcccgcgaa aaagccaaac gcgctgccga
    26701 ttggattgcc ctggaagaag ccatggaaaa cggcaacatc ctgtccggca tcatcaacgg
    26761 caaagtcaaa ggcggcctga ccgttatgat tagcagcatc cgcgcattcc tgccgggttc
    26821 tttggtcgac gtacgtcctg taaaagacac ttctcacttc gaaggcaaag agatcgaatt
    26881 caaagtgatc aaactggaca aaaaacgcaa caacgtcgtt gtttcccgcc gcgccgttct
    26941 ggaagccact ttgggtgaag aacgcaaagc cctgctggaa aacctgcaag aaggctccgt
    27001 catcaaaggc atcgttaaaa acattaccga ttacggtgca ttcgttgact tgggcggcat
    27061 cgacggtctg ttgcacatca ccgatttggc atggcggcgc gtgaaacacc cgagtgaagt
    27121 cttggaagtc ggtcaggaag ttgaagccaa agtattgaaa ttcgaccaag aaaaacaacg
    27181 cgtttccttg ggtatgaaac aactgggcga agatccttgg agcggtctga cccgccgtta
    27241 tcctcaaggc acccgcctgt tcggcaaagt atccaacctg accgactacg gcgcattcgt
    27301 cgaaatcgaa caaggcatcg aaggtttggt acacgtctcc gaaatggact ggaccaacaa
    27361 aaacgtacac ccgagcaaag tcgtacaact gggcgacgaa gtcgaagtca tgattttgga
    27421 aatcgacgaa ggccgccgcc gtatctcttt gggtatgaaa caatgccaag ccaatccttg
    27481 ggaagaattt gccgccaacc acaacaaagg cgacaaaatc tccggcgcgg ttaaatccat
    27541 taccgatttc ggcgtattcg tcggcctgcc cggcggcatc gacggtttgg ttcacctgtc
    27601 cgacctgtcc tggaccgaat ccggcgaaga agccgtacgc aaatacaaaa aaggcgaaga
    27661 agtcgaagcc gtcgtattgg caatcgacgt ggaaaaagaa cgcatctcct tgggtatcaa
    27721 acaactggaa ggcgatccgt tcggcaactt catcagcgtg aacgacaaag gttctttggt
    27781 taaaggttcc gtgaaatctg tcgatgcgaa aggcgccgtt gtcgccctgt ctgacgaagt
    27841 agaaggctac ctgcctgctt ccgaatttgc agccgaccgc gttgaagatt tgaccaccaa
    27901 actgaaagaa ggcgacgaag ttgaagccgt catcgttacc gttgaccgca aaaaccgcag
    27961 catcaaactt tccgttaaag ccaaagatgc caaagaaagc cgcgaagcac tgaactccgt
    28021 caatgccgcc gccaatgcga atgccggcac caccagcttg ggcgacctgc tgaaagccaa
    28081 actctccggc gaacaagaat aaggttgcag acatgacaaa gtctgagtta atggttcgtt
    28141 tggcagaagt gtttgccgcc aaaaacggca cgcatcttct ggcaaaagac gtagagtaca
    28201 gcgtaaaagt cttggttgac accatgacta gatcgcttgc ccgaggtcaa cgcatcgaaa
    28261 tccgcggttt cggcagcttc gatttgaacc atcgtcctgc ccgcatcggt cgcaatccca
    28321 aaaccggcga gcgtgtggaa gtacctgaaa aacatgtacc ccacttcaag cccggtaaag
    28381 aattgcgcga gcgggtcgac ttggctttaa aagaaaatgc caattaaacc ttagcatcaa
    28441 aacgccgctg ttacgcggcg ttttttctgt ggtttaactt catccgctgc ttcaatacct
    28501 tgagccaagc aagcaacgga ttagagcgtg gattttttta tagtggatta acaaaaacca
    28561 gtacggcgtt gcctcgcctt agctcaaaga gaacgattct ctaaggtgct gaagcaccaa
    28621 gtgaatcggt tccgtactat ctgtactgtc tgcggcttcg tcgccttgtc ctgatttttg
    28681 ttaatccact atatcattgc ttacaatccg ctttttaaac aacaaatttt tgatttctat
    28741 tacgaacagg acaaaaatcc tgcttattgc actaaaacta agccgtttca ggaatttgcg
    28801 gcaaatttac agcttttacc gagcctaatg ctttcgcttt ttggtaaaac gccaatttgt
    28861 attcaagcaa atctaaatag cgttttaatt cggcaatttg acacttcaca ttttctattt
    28921 gattttcaaa caaggaaagg cgttcttcaa tggtatcgtc gccaatgacg gtacattccg
    28981 caaagcgttt gatgtctttt aagctcattc ccgtattttt caagcattgc aataagccca
    29041 accattgcaa atcgttatcg gtaaaacagc ggttaccgta ttcatcacgt ccgatattag
    29101 gcaacaaacc ttctttgtcg taaaaacgta gggtgtgggc ggagatgcct attttttcgg
    29161 cggctttggc agtggtataa gtcattttcc ctccttctaa acaacaac
//
LOCUS       DAXISH010000018        29003 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.018, whole genome shotgun sequence.
ACCESSION   DAXISH010000018 DAXISH010000000
VERSION     DAXISH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 29003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29003
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.018"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(51..536)
                     /locus_tag="ACFOV4_000824"
     CDS             complement(51..536)
                     /locus_tag="ACFOV4_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009349087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FxsA family protein"
                     /protein_id="HFC7618868.1"
                     /translation="MRFFGIGFLVLLFLEIMSIVWVADWLGGGWTLFLMAAGFAAGVL
                     MLRHTGLSGLLLAGAAMRSGGRVSVYQMLWPIRYTVAAVCLMSPGFVSSVLAVLLLLP
                     FKGGAVLQAGGAENFFNMNQSGRKEGFSRDDDIIEGEYTVEEPYGGNRSRNAIEHKKD
                     E"
     gene            complement(866..1174)
                     /locus_tag="ACFOV4_000825"
     CDS             complement(866..1174)
                     /locus_tag="ACFOV4_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618869.1"
                     /translation="MTNNVDLKVPAKRYFTLDELCGLLQISPYGFAQWQHNHGVVVGY
                     GGERYTRLDVVKLLKLQSTFAPYAEGAESGSDGNRPVTLQEIGDGLKDLLADLDKELC
                     "
     gene            complement(1158..1460)
                     /locus_tag="ACFOV4_000826"
     CDS             complement(1158..1460)
                     /locus_tag="ACFOV4_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002641098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HFC7618870.1"
                     /translation="MTLTKAELADILVDKVSNVTKNDAKEIVELFFEEIRSTLASGEE
                     IKISGFGNFQLRDKPQRPGRNPKTGEEVPITARRVVTFHASQKLKSMVEHYYDKQR"
     gene            complement(1534..3897)
                     /gene="pheT"
                     /locus_tag="ACFOV4_000827"
     CDS             complement(1534..3897)
                     /gene="pheT"
                     /locus_tag="ACFOV4_000827"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFC7618871.1"
                     /translation="MQFSYSWLKTQADTELSSDKLEHLLTMSGLEVEEAETAAPAFAG
                     VVIAEVKSVEKHPDADRLNVTRVDAGTGGLVQIVCGAPNVKAGIKVPCSLPGAVLPGN
                     FKIKPTKMRGVVSDGMLCSTDELGLPDDGVNGLHILPEDAPVGTNIREYLDLDDTLFT
                     LKITPNRADCLSIKGIAREVSALTGCAFRQPEIHTAPITGSRKQPVQIDAPADCGRFI
                     SRVIENVNARATTPDWMKQRLERSGIRSISALVDIGNYVMLEIGQPMHVFDADKLSGS
                     LHIRRAREGETLECLNEKTVSLSENTLVVADEKGVLSLAGLMGGAASAVSDGTQNIVL
                     EAAWFAPEIIAGKSRQYGFGSDSSFRFERGVDYRLQADAIERATELVLQICGGAAGEM
                     VEAQGELPEAKQVGLRLGRLKTVLGVDIPAEQVETILQHLGLQPEKTAEGFRVTAPSF
                     RFDIEIEADLIEEIGRVYGYENIPDDYTSGRLKMLELPETRRPRFAVYNEMAARGYRE
                     VVSYAFVDEQWEQDFAANADPIRLQNPLAAQYAVMRSTLIGGLVEILQNNLNRKQNRV
                     RVFEIARVFGKGSDGRFVQNERIGGLWYGAAMPEQWGGKTRNADFYDIKADVENLLKN
                     KAVEFVKTGHPALHPGRAANIVSDGNVIGFVGELHPKWLQKYDLPQAPLVFEIDMAAV
                     LECGKTRYRAVSKFQPVRRDLAFVMPEAMSHDDLLLVLKGAANKLVQEISVFDVYRGT
                     GLPEGMKSVAVKVILQDMENTLTDEAVEPLIGKLIGAATAAGARLRS"
     gene            complement(3933..4451)
                     /locus_tag="ACFOV4_000828"
     CDS             complement(3933..4451)
                     /locus_tag="ACFOV4_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618872.1"
                     /translation="MSEIINLTESGITFNLVKNNLFYIEPYIRKRRQEGIKTVEFIYL
                     QEDNLLFVEAKQSIPNQERSPERFDEYISEIYQKWCNALNVEILGILGREDIKETIMP
                     SAFSNLQWGSIEIKLLLVIPDVPLNYLGQLNELIKQEFNKKDTLRLISLWNISVEVIN
                     RDLAIQKGLASS"
     gene            complement(4458..5522)
                     /locus_tag="ACFOV4_000829"
     CDS             complement(4458..5522)
                     /locus_tag="ACFOV4_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFC7618873.1"
                     /translation="MIKSFELENFGPISLLKADNLGKINLIIAENSKGKTFILKALYS
                     VLKSHEEAHKGKNIRDFSEELRDKLYWTFQVEEIGDLVTRGKENPNERPLKLSMTLED
                     SSSVLFSFGRTTKKLIKPELYELSPRINANSIFLPPKEVLSLFDVIKKSEEEKRFGFD
                     ATYIDLVKALDIKPTKGRNYPEAAEARKDLEALFGGYVSYNDKKKAWVYEKDRQTFSI
                     NSTAEGVKKIGILDTLLGNRFLSPGSILFIDEPEANLHPKAINQFLEILFSLSKSKLG
                     IQIFMSTHSYFVIKKLCLLARKHSESIPVFMPGKEKEQTTWVQENLQNSMPDNEIIGE
                     SIRLFREEIGVLSPETAWIG"
     gene            complement(5699..6691)
                     /gene="pheS"
                     /locus_tag="ACFOV4_000830"
     CDS             complement(5699..6691)
                     /gene="pheS"
                     /locus_tag="ACFOV4_000830"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003744233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFC7618874.1"
                     /translation="MENVNRIVAEGIAAVEAAQDFNALEQIKARYLGKTGELTGLLKT
                     LGQMSPEERKTIGAHINECKNRFQTAFNAKRDALNEAKLQARLAAEALDITLPGRAQE
                     GGSLHPVTLTLQRVVELFHGMGFEVADGPEIEDDFHNFQALNIPANHPARAMQDTFYV
                     ENGDVLRTHTSPIQIRYMLDKKEPPIRIIAPGRVYRVDSDATHSPMFHQAEGLWVEEG
                     VTFADLKAVFTDFIRRFFERDDLQVRFRPSFFPFTEPSAEIDIMGENGKWLEVGGCGM
                     VHPNVLKNVNIDSEKYTGFAFGIGLDRFAMLRYNVNDLRLFFDNDLNFLKQFVK"
     gene            complement(7037..7396)
                     /gene="rplT"
                     /locus_tag="ACFOV4_000831"
     CDS             complement(7037..7396)
                     /gene="rplT"
                     /locus_tag="ACFOV4_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFC7618875.1"
                     /translation="MPRVKRGVTARARHQKIFALAKGYRGRRKNVYRVAKQAVMKAGQ
                     YAYRDRRQRKRQFRQLWIVRINAGARENGLSYSKFMNGLKRASIEIDRKVLADLAVFD
                     KAAFAQLVEKAKAALAA"
     gene            complement(7409..7606)
                     /gene="rpmI"
                     /locus_tag="ACFOV4_000832"
     CDS             complement(7409..7606)
                     /gene="rpmI"
                     /locus_tag="ACFOV4_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFC7618876.1"
                     /translation="MPKMKTKSSAKKRFKVLGNGGVKRAHAFKRHILTKKTTKNKRQL
                     RGTSMVNDRDLASVAKMLPYA"
     gene            complement(7753..8274)
                     /gene="infC"
                     /locus_tag="ACFOV4_000833"
     CDS             complement(7753..8274)
                     /gene="infC"
                     /locus_tag="ACFOV4_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFC7618877.1"
                     /translation="MIAQEREARINGEITAKEVRLISESGEQLGVVSVREALAMAEGQ
                     DVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDY
                     QIKMRNINRFLADGDKVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKME
                     GRQMVMMIAPKKK"
     gene            complement(8292..10205)
                     /gene="thrS"
                     /locus_tag="ACFOV4_000834"
     CDS             complement(8292..10205)
                     /gene="thrS"
                     /locus_tag="ACFOV4_000834"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFC7618878.1"
                     /translation="MLNITLPDGSVRQYESPVTVAQIAASIGVGLARAAVAGRVNGKL
                     VDACDPIVENSAVQIITPKDQEGIEIIRHSCAHLVGHAVKQLYPNAKMVIGPVIEEGF
                     YYDIATEKPFTPEDVAAIEARMKELIAQDYDVVKIMTPRAEAIKIFQERGEEYKLRLI
                     DDMPEVEAMGMYHHQEYVDMCRGPHVPNTRFLKNFKLTKLAGAYWRGDSNNEMLQRIY
                     GTAWATKDELKAYIQRIEEAEKRDHRKLGKQLDLFHLQDEAPGMVFWHPKGWALWQVI
                     EQHMRKELNAAGYKEVKTPQIMDKTFWEKSGHWDNYKDNMFVTSSEKREYAVKPMNCP
                     GHVQIFNNGLRSYRDLPMRLAEFGSCHRNEPSGALHGLMRVRGFVQDDAHIFCTEDQI
                     VSEARAFNELLVRIYKQFGFHDVSVKLSLRPEKRAGSDDVWDKAEQGLREALTACGVE
                     WGELPGEGAFYGPKIEYHVRDALGRSWQCGTLQLDFVLPERLGAEYVTENNDRSRPVM
                     LHRAILGSLERFIGILIENHAGSFPLWLAPVQMVIMNITENQADYCREVAAKLQAAGF
                     RAELDLRNEKIGYKIRDNSQYRFPYQIVVGDKEKQENKVAVRRKAEDLGSLDLDDFIA
                     QLQQEITDALVNH"
     gene            complement(10259..10335)
                     /locus_tag="ACFOV4_000835"
     tRNA            complement(10259..10335)
                     /locus_tag="ACFOV4_000835"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10299..10301),aa:Val,seq:gac)
     gene            10514..11629
                     /gene="tgt"
                     /locus_tag="ACFOV4_000836"
     CDS             10514..11629
                     /gene="tgt"
                     /locus_tag="ACFOV4_000836"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFC7618879.1"
                     /translation="MLKFTLHKKDGYARRGTLELNHGKIETPVFMPVGTYGSVKAMNP
                     QNLHDIKAQIILGNTYHLWLRPGLEVVEQFGGLHGFIGWDKPILTDSGGFQVFSLSDM
                     RKLTEEGCTFKSPINGDKLFLSPEISMKIQTVLNSDIAMQLDECTPGEATREQARKSL
                     QMSLRWAERSKKAFEDLKNPNALFGIVQGAMYEDLREESLKGLEELDFPGLAIGGLSV
                     GEPKPEMYRMLRAVGPILPEHKPHYLMGVGTPEDLVYGVAHGVDMFDCVMPTRNARNG
                     WLFTRFGDLKIKNAKHKLDKRPIDESCTCYACQNFSRAYLHHLHRAGEILGAQLNTIH
                     NLHFYQVIMAEMRDAIEQGKFADWQARFHENRARGTD"
     gene            11639..12721
                     /gene="hemH"
                     /locus_tag="ACFOV4_000837"
     CDS             11639..12721
                     /gene="hemH"
                     /locus_tag="ACFOV4_000837"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HFC7618880.1"
                     /translation="MPSEAASDGILPLYPTRTIFQKPIMLPFFPEPSLSYTQQNRTAV
                     LLLNLGTPDAPTAQAVRPYLKSFLTDRRVVELPKWLWYPILHGLVLTLRPKKSAYAYE
                     KIWFKEGSPLEVYTARQAAALAERMPDLIVRHAMTYGNPSVADVLSELKAQGAGRLLV
                     IPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVRTVSRFYDDTGYIDAMKNHILRYWAE
                     HGRGKKLMLSFHGVPQKHYDLGDPYPDECRHTAKLLAEALELTEDQYVVSFQSQFGRA
                     KWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEEIALMGREQFYEAGGKSYRY
                     IPCLNDNPDWIDALVALAEENLGGWR"
     gene            12913..13314
                     /locus_tag="ACFOV4_000838"
     CDS             12913..13314
                     /locus_tag="ACFOV4_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HFC7618881.1"
                     /translation="MNTTRLPTALVLGCLCAAASAADNSIMTKGQKVYESNCVACHGK
                     KGEGRGTMFPPLYRSDFIMKKPQVLLHSMVKGINGTIKVNGKTYNGFMPATAISDADI
                     AAVATYIMNAFDNGGGSVTEKDVKQAKGKKN"
     gene            complement(13377..13667)
                     /locus_tag="ACFOV4_000839"
     CDS             complement(13377..13667)
                     /locus_tag="ACFOV4_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003696797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618882.1"
                     /translation="MAKYFTETGISVREYFDFFGEFVVLPAARSGDLALAYGLRLEAG
                     EEGLSLAELFDKRSDSQEPVECGRIDIGGFMLTAKEVDGDGNIGSMGLKVPR"
     gene            complement(13820..14140)
                     /locus_tag="ACFOV4_000840"
     CDS             complement(13820..14140)
                     /locus_tag="ACFOV4_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium:proton antiporter"
                     /protein_id="HFC7618883.1"
                     /translation="MDWMGSLFLPGGALLFLSVVSTTLPARLGMPLLLVSPAGVLDGA
                     AEALAIAAFLMLVARPPAVFGGLWKFNYSLREKAYSRIEMQSDTVLQAGIWRGTSCPT
                     ARSI"
     gene            14336..15062
                     /locus_tag="ACFOV4_000841"
                     /pseudo
     CDS             14336..15062
                     /locus_tag="ACFOV4_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 family protein"
     gene            15131..16669
                     /gene="lnt"
                     /locus_tag="ACFOV4_000842"
     CDS             15131..16669
                     /gene="lnt"
                     /locus_tag="ACFOV4_000842"
                     /EC_number="2.3.1.269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HFC7618884.1"
                     /translation="MFSKLDKYWQHPALYWPLLILFAAATPFTFAPYYHFWLMPLIFG
                     AFVRLIELRPRFAVSSAYLFSLTAYTTQFYWIHTALHDVSGLPDLYAVPLTFLLPAYL
                     ALYPALCFWLWKKFTLPRGIKIGLVLPILWTLTEFARERFLTGFGWGAIGYSQITPDS
                     PLAGFAPLGGIHMVTLATAFLGVWLVLASDNTARSGKRLLPIILIAALLAAGYTARQT
                     DFTRPDGSRSTVALLQGNIDQTLKWREDQVIPTIQKYYEQVGKTTADIVILPETAIPV
                     MRQNLPENILAKFAEQAQNNGSALAVGISQYTSDGNGYENAVINLTGYQENNQDGIPY
                     YAKNHLVPFGEYKPLPFLTTPLYKMMNMPLSDFRKGGGKQSALLMKNQKIAFNICYED
                     GFGDELIAAAKDATLLANASNMAWYGKSNAMYQHLQQSQARAMELGRYMVRATNTGAT
                     AIISPKGNIIAQAQPDTETVLEGHIKGYVGETPYMKTGSSWWLMGILTLAALILFIFR
                     NKEH"
     gene            16933..17796
                     /gene="rpoH"
                     /locus_tag="ACFOV4_000843"
     CDS             16933..17796
                     /gene="rpoH"
                     /locus_tag="ACFOV4_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HFC7618885.1"
                     /translation="MNNAFALPAIQSGNGSLEQYIHTVNSIPMLSQEEETRLAERRIK
                     GDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLF
                     SFAVHWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNLNALSPKEAQDIADD
                     LGVKLSEVLEMEQRMTGHDIAIMADNSDDEDSFAPIDWLADHDSEPSRQLSKQAHYAL
                     QTEGLQNALAQLDDRSRRIVESRWLQDDGGLTLHQLAAEYGVSAERIRQIEAKAMQKL
                     RGFLTEEAEAV"
     gene            complement(17855..18001)
                     /locus_tag="ACFOV4_000844"
     CDS             complement(17855..18001)
                     /locus_tag="ACFOV4_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618886.1"
                     /translation="MLIHYINSANLSEKQLMRQCLVHVCFLISAIAMVWTDKIVYGTT
                     HKPH"
     gene            18280..19164
                     /locus_tag="ACFOV4_000845"
     CDS             18280..19164
                     /locus_tag="ACFOV4_000845"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFC7618887.1"
                     /translation="MSSGNIHIHSMTGFANAAAECGSKRINLDIRAVNHRFLDIQIRM
                     PDDLRYLESGIREKISSHIARGKVECKIQIQDTENSRQSLELNSDLVNQLAEINKNLR
                     KHHDLAKLGVADILRFPGVLASQRENTEELAKSITELTEKALKDFTAARRREGKKLGE
                     HLLQRLESMEEIIDALSELFPTLLETHKEKIRARLVEAVGDINNDRLQQEFALFIQKS
                     DIDEEFSRLRTHIDEVRRIVTEHKGSSGKRLDFLMQELNREANTLGSKSIAAECTQAS
                     VELKVLIEQMREQVQNIE"
     gene            complement(19248..19763)
                     /locus_tag="ACFOV4_000846"
     CDS             complement(19248..19763)
                     /locus_tag="ACFOV4_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFC7618888.1"
                     /translation="MMTLKTAPLKRRFAAMLYEMLLVGAATCLAALFAGIAAIFLNPV
                     SIAVSALVTSILIMGAWWLYFRANWHGQGQTLAMRTWKIGLCDLNGIQPSLYLLRLRF
                     IWACIFIVFIPMLAYAGLRHFLGIPPKGAAGAALIWLILPWGFALLNPDRQFLYDFLA
                     GTRLVAVKGKP"
     gene            complement(19839..20258)
                     /locus_tag="ACFOV4_000847"
     CDS             complement(19839..20258)
                     /locus_tag="ACFOV4_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618889.1"
                     /translation="MDNKTKLRLGGLILLTTAVLSLIIVLIVDSWPLAILLAAVIVAA
                     AAGGFVWTSRRQQRQFIERLKKFDIDPEKGRINEANLRRMYHSGGQHQKDAITLICLS
                     QKCSVDEAHAMFKKRPTRQEINQMAAKQSRGQKRPHR"
     gene            complement(20379..21377)
                     /gene="holA"
                     /locus_tag="ACFOV4_000848"
     CDS             complement(20379..21377)
                     /gene="holA"
                     /locus_tag="ACFOV4_000848"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFC7618890.1"
                     /translation="MAAHIGRIDTDAPLKPLYVIHGEEELLRIEALDALRAAAKKQGY
                     LNREVYTADNAFDWNELLQTAGSAGLFADLKLLELHIPNGKPGKTGGEALQDFAARLP
                     EDTVTLVLLPKLEKTQLQSKWFAALAAKGEVWEAKPVGAAALPQWIRGRLDKIGLGIG
                     ADALALFAERVEGNLLAARQEIDKLALLYPKGHTVNIDEAQTAVANVARFDVFQLAGA
                     WMKGDVPRVCRLLDGLQEEGEEPVLLLWAVAEDVRTLIRLAAVLKQGQGVQSVRNSLR
                     LWGDKQTLAPLAVKRISVVRLLDALKTCAQIDRIIKGAEDGDAWTVFKRLVVSLAE"
     gene            complement(21379..21858)
                     /gene="lptE"
                     /locus_tag="ACFOV4_000849"
     CDS             complement(21379..21858)
                     /gene="lptE"
                     /locus_tag="ACFOV4_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0043165 - Gram-negative-bacterium-type cell
                     outer membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HFC7618891.1"
                     /translation="MNKLFLTAAVLMLGACGFHLKGADGISPPLTYRSWHIEGGQALR
                     FPLETALYQASGRVDDAAGAQMTLRIDSVSQNKETYTVTRAAVINEYLLILTVEAQVL
                     KRGEPVGKPMTVSVRRVLAYADNEILGKQEEEAALWAEMRQDAAEQIVRRLTFLKAE"
     gene            complement(21910..22689)
                     /gene="pgeF"
                     /locus_tag="ACFOV4_000850"
     CDS             complement(21910..22689)
                     /gene="pgeF"
                     /locus_tag="ACFOV4_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HFC7618892.1"
                     /translation="MKTITETLNLAPKGKNFLTADWPAPANVKTLITTRNGGVSQGAY
                     QSLNLGTHVGDNPEAVRRNREIVQQQVGLPVAYLNQIHSTIVVNAAEALGGTPDADAS
                     VDDTGKAACAVMTADCLPVLFCDRAGTAVAAAHAGWRGLAGGVLQNTIAAMKVPPVEM
                     MAYLGPAISADAFEVGQDVFDAFCTPMPEAAAAFEGIGGGKFLADLYALARLILKREG
                     VGGVYGGTHCTVLERDTFFSYRRDGATGRMASLIWLDGNAV"
     gene            22856..22969
                     /locus_tag="ACFOV4_000851"
                     /pseudo
     CDS             22856..22969
                     /locus_tag="ACFOV4_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            23248..24195
                     /locus_tag="ACFOV4_000852"
     CDS             23248..24195
                     /locus_tag="ACFOV4_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HFC7618893.1"
                     /translation="MNILSKISSFIGKTFSLWAALFAAAAFFAPDTFKWAGPYIPWLL
                     GIIMFGMGLTLKPSDFDILFKHPKAVIIGVIAQFAIMPATAWLLSKLLNLPAEIAVGV
                     ILVGCCPGGTASNVMAYLARGNVALSVAVTSVSTLISPLLTPAIFLMLAGEMLEIQAA
                     GMLMSIVKMVLLPIVLGLIVHKVLGSKTEKLTDALPLVSVAAIVLIIGAVVGASKGKI
                     MESGLLIFAVVVLHNGIGYLLGFFAAKWTGLPYDAQKTLAIEVGMQNSGLAAALAAAH
                     FAAAPVVAVPGALFSVWHNISGSLLATYWAAKAGKHKKP"
     gene            complement(24348..25472)
                     /gene="rluD"
                     /locus_tag="ACFOV4_000853"
     CDS             complement(24348..25472)
                     /gene="rluD"
                     /locus_tag="ACFOV4_000853"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HFC7618894.1"
                     /translation="MQNTSFDNESDYSDDSDFASASETENRIGLTVPLELAGGRLDAV
                     LAKLLPDYSRSRLTSWIKEGAVIVNDKPSQPKDKMIGGEQICVTVRPSEENLAFVPEP
                     MALDIVYEDDTVIVVNKPAGLVVHPAAGNWTGTLLNGLLAHCPELSQVPRAGIVHRLD
                     KETSGLMVVAKTLPAQNSLVQQLQERTVKRIYRAVANGIVPFDGKIETQIGRDPHNRL
                     KMAVVKFGGKPAVTHVKVLERYLAHSYIECSLETGRTHQIRVHMREANHPLAADPVYG
                     NPRHPCGDTVKEAVKSLGARQALHAYRLSFTHPKTGETVSFEAPIPDDIYHLLSVLRL
                     EAGLDSSLSNEEEWQDKFGADDDDDWNEDDYDVEVVYVRE"
     gene            25471..26274
                     /locus_tag="ACFOV4_000854"
     CDS             25471..26274
                     /locus_tag="ACFOV4_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HFC7618895.1"
                     /translation="MKKILLTVSLGLALSACATQGTVDKDAQITQDWSVEKLYAEAQD
                     ELNSSNYTRAVKLYEILESRFPTSRHARQSQLDTAYAYYKDDEKDKALAAIERFRRLH
                     PQHPNMDYALYLRGLVLFNEDQSFLNKLASQDWSDRDPKANREAYQAFAELVQRFPNS
                     KYAADATARMVKLVDALGGNEMSVARYYMKRGAYIAAANRAQKIIGSYQNTRYVEESL
                     AILELAYQKLGKPQLAADTRRVLETNFPKSPFLTHAWQPDDMPWWRYWH"
     gene            complement(26332..28551)
                     /locus_tag="ACFOV4_000855"
     CDS             complement(26332..28551)
                     /locus_tag="ACFOV4_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFC7618896.1"
                     /translation="MFRRWFLPCWVVGAAASFALPVVPHWLFWLAAFAVFAVFARRFA
                     FAGLMLCVLAGAAYGVFRTEAALSSQWWAEAVSGVPLTVEVADMPRSDGRRVQFAAKA
                     VDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGA
                     GTVGADRVLLHGGSGWGIAVWRSRISRNWQQADADGGLSDGIGLMRALSVGEQSALRP
                     ELWQAFRPLGLTHLVSISGLHVTMVAVMFAWLAKRLLACSPRLPARPRAWVLAAGCAG
                     ALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALAAVLLFDPSAVLGVG
                     TWLSFGLVAALIWACSGRLHEGKRQTALRGQWAASVLSLVLLGYLFASLPLVSPLVNA
                     VAIPWFSWVLTPLALLGSVVPFAPLQQLGAFLAEYTLRFLVWLADVSPEFAVASAPLP
                     LLVLAVCAALLLLLPRGLGLRPWAVLLLAGFVFYRSPGVPENEVAVTVWDAGQGLSVS
                     VQTANHHLLFDTGTAAAAQMGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQAVGKIPN
                     GGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLMPSERKNIDDNGKSCVLRVVAGGAAL
                     LVTGDLDTKGEESLVGKYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYA
                     NAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGGVKAQRLRGYKFYWQKKPFE"
BASE COUNT         7212 a         8252 c         6760 g         6779 t
ORIGIN      
        1 tcaaaccgga aaaatgccgt ctgaatcttc agacggcatt ccattcatat ttattcgtct
       61 tttttgtgtt cgatggcgtt tcgggaacga ttgccgccgt aaggctcttc aaccgtatat
      121 tccccctcga taatatcgtc atcgcgggaa aagccctctt ttctgcccga ttggttcatg
      181 ttgaaaaaat tttccgcacc tcctgcctgc aacactgcac ctcccttaaa cggcagcagc
      241 agcaacaccg ccaacaccga ggatacgaat cccggactca tcagacacac cgccgccacc
      301 gtataacgga taggccacaa catctgataa acggataccc tcccgccgct tctcattgcc
      361 gcgcccgcca ataaaagacc ggacagcccc gtatgcctga gcatcagcac accggcggca
      421 aaacctgccg ccatcaaaaa caacgtccag ccgccgccca accaatcggc aacccacaca
      481 atcgacataa tctccaaaaa cagcagcacc aaaaaaccga taccgaaaaa tctcattgac
      541 cgtcatcctt atatttaagt aaacagcaaa ccgcccgaac aggactccaa gcgacctgcc
      601 tgtaaatgat tacaaaacca tgtgcttcaa gccgaaacaa tgtgaaatca cgcaatatag
      661 tggattaaca aaaaccagta cggcgttgcc tcgccttagc tcaaagagaa cgattctcta
      721 aggtgctgaa gcaccaagtg aatcggttcc gtactatttg tactgtctgc ggcttcgtcg
      781 ccttgtcctg atttttgtta atccactata attatttttt agcgtgtaaa acaaaaccgg
      841 ctgcatacct gcaaccggcc tcaaatcagc acaattcctt atccaaatcc gccaacaggt
      901 ctttcagacc gtctccgatt tcctgaagcg taaccggacg gttgccgtcc gaacccgatt
      961 ccgcaccttc tgcatacggt gcaaacgtgc tctgcaattt caacagtttc accacatcca
     1021 aacgggtgta gcgttcgccg ccgtaaccga caaccacacc gtgattatgc tgccattgcg
     1081 caaaaccata ggggctgatt tgcaacagtc cgcacaactc gtccagcgtg aaatagcgtt
     1141 ttgcgggaac cttcaaatca acgttgtttg tcatagtagt gttccaccat gcttttgagt
     1201 ttctggctgg catggaaagt taccacgcgg cgggcggtaa tcggcacttc ctcgccggtt
     1261 ttaggattac gacccgggcg ttgcggcttg tcgcgcaact ggaaatttcc gaaaccggaa
     1321 attttgattt cttcgccgct tgccaaagtg ctgcggattt cttcaaaaaa gagttcgacg
     1381 atttctttgg catcgttttt ggtgacgttg ctgactttgt ctaccaaaat atcggccagt
     1441 tctgctttag tgagagtcat atgattacct tctgttgtaa cagttgtgga ttattaccaa
     1501 tttttattta aaattcaagc gaatatttat tttttaactg cgaagccgcg cccctgccgc
     1561 cgttgccgcg ccaatcagtt ttccgataag cggctcgacc gcctcatccg tcagcgtgtt
     1621 ttccatatcc tgcaaaatca ctttgaccgc cacgctcttc atcccttcgg gcagtcccgt
     1681 gccgcgatac acgtcaaaca cgctgatttc ctgtaccaac ttgtttgccg cgcctttcaa
     1741 gacaagcagc aaatcatcat ggctcatagc ttccggcatc acaaacgcca aatcgcggcg
     1801 caccggctgg aatttcgata cggcccgata gcgcgttttc ccgcattcca acacggccgc
     1861 catatcgatt tcaaatacca gcggcgcttg cggcaggtcg tatttttgca gccatttcgg
     1921 atgcagttcg ccgacaaagc cgatgacgtt gccgtctgaa acgatattgg cggcgcgtcc
     1981 gggatgcagg gcaggatgtc cggttttaac gaactcgacc gctttgtttt tcaacagatt
     2041 ttccacatct gccttaatgt cgtaaaaatc cgcattgcgc gttttcccgc cccattgttc
     2101 gggcattgcc gcgccgtacc acaagccgcc gatgcgttcg ttttggacaa accggccgtc
     2161 tgaacctttg ccgaacacgc gggcgatttc aaacacgcgc acgcggtttt gtttgcggtt
     2221 caggttgttt tgcaaaattt ccaccaagcc gccgatgagt gtggaacgca tcacggcata
     2281 ttgcgccgcc agcgggtttt gcaggcggat ggggtcggcg ttggcggcaa aatcttgttc
     2341 ccactgctcg tcaacgaagg catagctgac cacttcgcgg tagccgcgcg ccgccatttc
     2401 gttgtaaacg gcaaaacgcg ggcggcgtgt ttcgggcagt tccagcattt tcagacggcc
     2461 tgacgtgtaa tcgtcgggga tgttttcata gccgtaaacg cgtccgattt cttcaatcaa
     2521 atcagcctca atttcgatgt caaaacggaa gctcggcgcg gtaacgcgga agccttccgc
     2581 cgttttctcg ggctgcaggc ccaagtgttg caaaatggtt tccacctgtt cggcaggaat
     2641 gtccacgccc aacacggttt tcagacggcc caaacgcaat ccgacctgct tcgcttcggg
     2701 caattcgcct tgcgcttcca ccatttcgcc tgccgcaccg ccgcaaatct gcaacaccaa
     2761 ttcggtagca cgctcaatgg catccgcctg caaacggtaa tccacgccgc gctcgaagcg
     2821 gaacgacgaa tccgaaccga aaccgtattg gcgcgatttg ccggcgatga tttcgggcgc
     2881 aaaccaagcc gcttccagca cgatattttg cgtgccgtct gaaaccgcgc tcgccgcgcc
     2941 gcccattaag cccgccaaac tcaacacgcc tttttcgtcc gccacgacca gcgtgttttc
     3001 agacagggaa acggttttct cgttcaggca ttccagcgtt tccccttcgc gcgcgcggcg
     3061 gatgtgcagg ctgccggaaa gtttgtcggc atcaaaaacg tgcatcggct gaccgatttc
     3121 cagcatcaca taattgccga tgtccaccag cgcggaaata ctgcggatgc cgctgcgctc
     3181 caaacgttgt ttcatccaat ccggcgtagt agcgcgcgcg ttcacgtttt caatcacacg
     3241 gctgataaag cgaccgcaat cggcaggcgc gtcaatctgc acgggctgtt ttcgactgcc
     3301 cgtgatcggc gcggtatgga tttcgggctg cctgaacgcg caccccgtca atgcggacac
     3361 ttcgcgcgca atgcctttga tgctcaagca gtcggcgcgg ttaggcgtaa ttttcaacgt
     3421 aaacagcgta tcgtccaaat ccaagtattc gcggatattg gtaccgacgg gcgcatcttc
     3481 aggcagaatg tgcaggccgt tcacaccgtc gtcgggcaga ccgagttcgt cggtggaaca
     3541 caacatcccg tccgacacca cgccgcgcat tttggtcggc ttgattttga aattgcccgg
     3601 caacactgcg cccggcaacg aacacggcac tttgatgccc gctttcacat tcggcgcacc
     3661 gcacacaatc tgcaccaacc cgcccgtacc cgcatcaact cgggtaacgt tcaaacggtc
     3721 tgcatccgga tgtttttcaa cggatttcac ttcggcaatc accacgcccg caaacgcagg
     3781 cgcggcagtt tcggcctctt ccacttccaa gccggacatc gttaacagat gttccagctt
     3841 atcggaggaa agttcggtat cggcttgggt tttcagccat gaataggaga attgcatgtt
     3901 atgttctcaa tcaattaatt aactttagat tttcaagagc tagctaaacc tttttgaatg
     3961 gctaagtccc tattaattac ttctacagaa atgttccata aagaaatcaa ccgcaaagta
     4021 tctttcttat taaattcttg ctttattaat tcattcaatt gcccaagata attaagcggc
     4081 acatccggga taaccagtaa taatttgatt tctatgctac cccattgcaa atttgaaaaa
     4141 gcactaggca taattgtttc tttgatatct tctctgccta atattcccaa aatttcaaca
     4201 tttaatgcat tacaccattt ttgataaatc tctgaaatat attcatcaaa acgctcagga
     4261 gatctttctt gatttggaat actttgtttt gcctcaacaa ataacaaatt atcttcttgc
     4321 agatagataa actctactgt cttaatacct tcttgccttc tcttccggat atatggttct
     4381 atataaaaca ggttattttt tactagatta aaagttatac ctgattcagt gagatttatt
     4441 atttcactca taaaaaccta accaatccat gctgtttccg gagataaaac acctatttct
     4501 tctctgaaca atcgaataga ctcaccaata atttcattat ccggcatgct attttgtaaa
     4561 ttttcctgca cccaagtagt ctgttccttt tctttgccag gcataaaaac aggaatactt
     4621 tcactatgct ttctagctaa taaacacagc ttcttgataa caaaatatga atgcgtactc
     4681 ataaaaatct gtattcccaa tttggattta gataaggaaa acagaatttc tagaaattga
     4741 ttaattgctt tcggatgtag attagcttct ggctcatcaa taaataagat tgatccagga
     4801 ctcaaaaacc gatttcctaa tagagtgtct aatatcccaa tcttttttac cccctctgct
     4861 gtagaattga tagagaaagt ttgtctatct ttttcatata cccatgcctt ctttttatca
     4921 ttgtagctaa cataaccgcc aaacaatgct tctagatcct ttctagcttc cgctgcctca
     4981 gggtaattcc tcccttttgt tggtttaata tccaatgctt ttaccaaatc aatgtaagta
     5041 gcatcaaaac caaatctctt ttcttcctct gattttttaa ttacatcaaa tagtgataga
     5101 acttctttgg gtggtaaaaa aatagagtta gcgtttattc tgggagaaag ttcgtatagc
     5161 tccggtttaa ttagcttttt ggtagttcta ccaaaagaaa acaaaactga agaactatct
     5221 tctaaagtca tacttaactt aagaggccgt tcgtttggat tttcttttcc tcttgtaact
     5281 aaatcaccaa tttcctctac ttggaacgtc caatatagct tatctcgcaa ttcctcagaa
     5341 aaatcacgaa tattctttcc tttatgagct tcctcatgac tttttaaaac actatataat
     5401 gcctttaaaa taaaagtttt ccctttgcta ttttctgcaa taattaaatt tattttccct
     5461 aaattatcag ccttcaataa gctaatcggc ccgaaatttt caagctcaaa tgatttaatc
     5521 atataatccc cctaatatat atcaacaata tttgtacaag ccacattgta aaaagacagc
     5581 aaccacagca ccatagtaaa cgcatagcag gcggataatg gagcgacata gcgtttcatg
     5641 atttagcttt ctgaggtagg cacaggctgc ttttttcatt tttaggcagc ctacacaatc
     5701 attttacaaa ctgcttcaaa aaattcaaat cgttatcaaa aaacaagcgc aaatcgttca
     5761 cgttgtaacg cagcatcgcg aaacggtcga gaccgatacc gaaagcgaaa ccggtgtatt
     5821 tttcagaatc gatattcaca tttttcaaca cgttgggatg caccatgccg cagccgccga
     5881 cttccagcca tttgccgttt tctcccataa tgtcgatttc ggcagacggt tcggtgaacg
     5941 ggaagaaaga cgggcggaaa cgtacttgca aatcatcgcg ttcaaagaag cgacggataa
     6001 aatccgtgaa cactgctttt aagtcggcaa aagttacgcc ctcttctacc cacaaacctt
     6061 ccgcctgatg gaacataggc gagtgcgtgg catcgctgtc cacacggtaa acgcggccgg
     6121 gggcgataat gcggatgggc ggctcttttt tatcgagcat atagcggatt tgaatcgggg
     6181 aagtgtgcgt acgcaaaaca tcaccgtttt caacgtaaaa cgtatcctgc atcgcacggg
     6241 caggatggtt tgcagggatg ttcagggctt ggaaattgtg aaaatcgtct tcgatttcag
     6301 gcccgtccgc cacttcgaaa cccattccgt gaaagagttc gaccacacgt tgcaaggtca
     6361 gggttacggg atgcaggctg ccgccttcct gagcgcgtcc gggcagggta atgtcgaggg
     6421 cttcggcggc aagtcgggct tgcagcttgg cttcgttgag ggcatcgcgt ttggcattaa
     6481 aagccgtctg aaaccggttt ttgcattcat tgatatgcgc acctatggtt ttgcgctctt
     6541 caggcgacat ttgccccaaa gttttcagaa gtccggtcaa ctcgccggtt ttgccaagat
     6601 aacgggcttt gatttgttct agagcgttga agtcttgcgc agcttctact gcggcaatgc
     6661 cttctgcaac gatgcggttt acattttcca taatatcaag tctgtcaatt aatgatatgc
     6721 cacctgaaac aacgaggccg cctgtatagc ctgacatatc agactcttca gacgacctta
     6781 ttttcttcac ggtcaatcca ttggataaat tttctgtata gtggattaaa tttaaaccag
     6841 tacggcgttg cctcgccttg ccgtactatc tgtactgtct gcggcttcgt cgccttgtcc
     6901 tgatttaaat ttaatccact atattttaac gcaaatttat ttaaaaaaat agactttaaa
     6961 gaaagaaaat caatcacata gaatttctgc aaacaaagaa aaaaggaagc cgcagcttcc
     7021 ttttcaattt tttggattaa gcagccaaag cagctttggc tttttcaacc aattgtgcaa
     7081 aagcggcttt atcgaacacg gccaaatcag ccaatacttt gcggtcgatt tcgatagagg
     7141 cgcgtttcag accattcata aatttgctgt aagacaaccc gttttcacgc gcacctgcat
     7201 tgatacggac aatccacaat tgacggaatt ggcgtttgcg ttggcggcgg tcgcggtatg
     7261 cgtattggcc ggctttcatt accgcctgct tggcaacgcg gtaaacgttt ttacgacggc
     7321 cgcggtagcc tttggctaac gcgaagattt tttggtgacg ggcacgggcg gtaacaccgc
     7381 gttttacgcg tggcatattc taaactcctt aagcgtaggg taacatttta gcaacagaag
     7441 ccaaatcgcg atcatttacc atagaggtac cgcgcagttg gcgtttgttt ttggtggtct
     7501 ttttagtcaa gatgtggcgt ttgaacgcat gagcgcgttt cacaccgccg ttacccagta
     7561 ctttaaagcg ttttttcgcg ctagacttgg ttttcatttt aggcatggga aaactccatt
     7621 cgttatcaga taaggcatta gggggtttta aaacatcggt ttcaaacact tgaacccaca
     7681 ataccacggt tttttgccgc aattgaaaac ttactccgaa gcggcaatcg gagtaagcgg
     7741 agaattatag ctttattttt tcttcggcgc aatcatcatc accatttggc gaccttccat
     7801 tttgggaaag gactcgattt gcgccacttc agccaaatct tctttcacac gttccaaaag
     7861 ttgcgcgccg agttgctggt gagccatttc acggccgcgg aaacgcaatg tcactttgac
     7921 tttatcgccg tcggcaagga agcggttgat gttgcgcatc ttgatttgat aatcgccctc
     7981 atccgtaccc ggacggaatt tgatttcctt gatttgcacc tgcttttggt ttttcttggc
     8041 ttcgtcgcgt ttcttggcct gctggtattt gtatttaccg taatccatca gtttgcacac
     8101 aggcggttta gcagttgggg aaatctctac caaatcgaca tcctgccctt cggccatagc
     8161 caaagcttca cgaactgaaa caacaccaag ctgttcgcct gactcactga ttaaacgcac
     8221 ttctttggcg gtaatttcgc cgttgattcg tgcttcgcgt tcttgagcga tgatgaatac
     8281 tcctataaaa attaatgatt gacgagggca tcagtgattt cttgctgcaa ttgcgcaatg
     8341 aaatcatcca aatccaaaga acccaaatct tctgctttgc ggcgtaccgc cactttgttt
     8401 tcctgcttct ccttatcgcc gacaacgatt tgataaggga aacggtattg gctgttgtcg
     8461 cggattttgt aaccgatttt ttcgttacgc aaatccaact cggcgcggaa tcctgccgcc
     8521 tgcaatttgg cagccacttc ccgacaataa tctgcctgat tttcggtaat attcataatc
     8581 accatttgaa ccggagccaa ccataacggg aaagagcctg catggttctc aatcagaatg
     8641 ccgataaatc gctccaaaga acctaaaatg gcgcgatgca acataacagg tcgcgagcgg
     8701 tcgttgtttt cggttacata ttctgcaccc aagcgttccg gcaagacgaa atccagttgt
     8761 aatgtaccgc attgccaaga acgacccaag gcatctctga catgatattc gattttaggc
     8821 ccgtaaaacg caccctcgcc cggcaattcg ccccattcca cgccgcaggc agtcaatgcc
     8881 tcgcgcaaac cctgctctgc cttatcccac acgtcatctg aacctgcacg tttttcaggg
     8941 cgaagagaaa gcttgacgga tacatcatgg aaaccgaact gtttgtagat gcgaaccaac
     9001 aattcattga acgcacgggc ctcgctgacg atttggtctt cggtacagaa aatatgcgca
     9061 tcatcctgca caaatccacg gacccgcatc agaccatgca atgcaccgct cggctcgttg
     9121 cggtggcagg aaccgaattc cgccaaacgc atcggcaaat ctcgatacga acgcaaaccg
     9181 ttgttaaaaa tttgaacatg acccggacag ttcatcggtt taaccgcata ttcgcgtttt
     9241 tccgaactgg ttacgaacat attatctttg tagttgtccc aatggccgga tttttcccaa
     9301 aaggttttat ccatgatttg aggcgttttg acctctttat aaccggcggc gttcagttct
     9361 ttacgcatat gctgttcaat cacttgccac aaagcccagc ctttaggatg ccaaaacacc
     9421 atgcccggcg cttcgtcttg cagatggaac agatccaatt gcttgccaag cttgcggtgg
     9481 tcgcgctttt cggcttcttc gatacgttga atataggctt tcaactcgtc ttttgtcgcc
     9541 caagccgtac cgtatatgcg ttgcagcatt tcattattgc tgtcgccgcg ccagtatgcg
     9601 cccgccagct tggtcagttt gaagtttttc aggaaacggg tattcggaac gtgcggaccg
     9661 cggcacatat cgacatattc ctggtgatga tacatcccca tcgcttccac ttcgggcata
     9721 tcgtcaatca ggcgcagttt gtattcttcg ccgcgctctt gaaaaatttt aatcgcctcc
     9781 gcacgcggag tcatgatttt gaccacatca tagtcttggg caatcaattc tttcatacgc
     9841 gcttcaatgg cggcaacatc ttccggtgta aacggttttt ccgtggcgat gtcgtaataa
     9901 aagccctctt caatgacggg gccgataacc atttttgcat taggatagag ttgcttgacg
     9961 gcatgcccga caagatgggc gcaggaatgg cggatgattt cgatgccttc ctgatctttc
    10021 ggagtaatga tttgaacagc agaattttca acaatcgggt cgcacgcatc gaccaatttg
    10081 ccgtttaccc tgcctgccac cgccgccctc gccaaaccga caccgataga cgcagcaatt
    10141 tgagccacgg taacggggga ttcgtattgg cggactgagc cgtccggcaa ggtaatgttc
    10201 aacatcaaaa agctccaaaa cattaaaaaa taacggcata aatgccgtta tgggaatttg
    10261 gtaggcacga ttggattcga accaacgacc cccaccatgt caaggtggtg ctctaaccaa
    10321 ctgagctacg tgccttcaaa gaatttttgc attttatcgg gtcgttttaa tttttgcaag
    10381 aggtatgtgc atttctttat gcaacattgt ggcaagattt ggggatgtcg tctgaaaaac
    10441 cgtgggaatt catttataat gccgtctttt aaaacatatt tcgccccctg tcgcccaact
    10501 gacattcaat cttatgctta aatttacctt acacaaaaaa gacggatacg cccgacgcgg
    10561 cacgctggag ttgaaccacg gcaaaattga aacgccggta tttatgcctg tcggtactta
    10621 cggctcggtt aaggcgatga acccgcaaaa cctgcacgac atcaaggcgc aaattatttt
    10681 gggcaacact tatcatttgt ggctgcgtcc gggcttggag gtcgtcgaac agtttggagg
    10741 gcttcacggc tttatcggct gggacaaacc gattctgacc gactcgggcg gttttcaggt
    10801 tttttctttg tcggatatgc gcaagctgac ggaagaaggc tgtacgttca aaagcccgat
    10861 caacggcgac aagctgtttt tatcgcctga aatttccatg aaaatccaaa cggttttgaa
    10921 ctcggacatc gcgatgcagc tggacgaatg cacgccgggc gaggcgacgc gcgaacaggc
    10981 gcgaaaatcg ttgcaaatga gcctgcgctg ggcggaacgg agcaaaaaag cctttgaaga
    11041 tttgaaaaac ccgaacgcac tgttcggcat cgtgcaaggc gcgatgtatg aagatttgcg
    11101 cgaagagtcg ctgaaaggct tggaagagct cgatttcccc ggcttggcca tcggcggctt
    11161 gtccgttggc gaacctaagc ccgaaatgta ccgcatgttg cgcgccgtcg gccctatcct
    11221 gccggaacac aaacctcatt atttaatggg cgtcggtacg cctgaagact tagtgtacgg
    11281 cgtggcacac ggcgtggata tgttcgactg cgtcatgcct actcgcaatg cgcgtaacgg
    11341 ctggctgttt acccgttttg gcgatttgaa gatcaaaaac gccaaacaca agctcgacaa
    11401 gcgtccgata gacgaaagct gcacctgcta cgcctgccaa aacttcagcc gcgcctacct
    11461 gcaccatctg caccgcgccg gcgaaatctt gggcgcacag ctcaacacca tccacaacct
    11521 gcatttctac caagtcatta tggcggaaat gcgcgatgcc atagaacaag gcaaatttgc
    11581 cgactggcag gcgcgattcc acgaaaaccg tgctcgcggc acagactgac tcccggcaat
    11641 gccgtctgaa gccgcttcag acggcatttt gccgctttac cctacccgca ctatttttca
    11701 gaaaccgatc atgcttccat tctttccaga accctccctt tcctatacgc aacaaaaccg
    11761 taccgccgtt ttgctgttga acctcggcac gcccgacgcg ccgaccgcgc aggcggtacg
    11821 accttatctg aagtcctttc tgaccgaccg gcgcgtcgtc gaactgccca aatggctgtg
    11881 gtatcccatt ctgcatggtc tggtactgac gttgcgcccc aaaaaaagcg cgtacgccta
    11941 tgaaaaaatc tggtttaagg aaggttcgcc cctagaagtt tacacagcac gccaagctgc
    12001 cgcgcttgcc gaacgtatgc ccgacctcat cgtccgccac gccatgacct acggcaatcc
    12061 ttcggtggca gacgtattgt cggaactgaa ggcgcaaggc gcgggcagac tgctggtcat
    12121 cccgatgtac ccgcaatatg ccgcttccag cagcggagcg gcagtagata aggtgtgcga
    12181 acaattactg ctgcaacgga accaaatgag cgtccgcacc gtttcgcgct tttatgacga
    12241 taccggctac attgatgcga tgaaaaacca catcctccga tattgggcgg aacacggacg
    12301 tgggaaaaaa ctgatgttga gttttcacgg cgtaccgcag aagcactacg acctcggcga
    12361 cccctatccc gacgagtgcc gccacaccgc caaactgctt gccgaagcac tggaactgac
    12421 cgaagaccaa tatgtcgtat cgttccaaag ccaattcggc agggcaaaat gggttacacc
    12481 gagcacgcag gatttgttcg gcaaactgcc caaacagggg gtaaccgagc tggacgtatt
    12541 ctgcccgggc tttttggcag actgtttgga aaccatggaa gaaatcgccc tgatggggcg
    12601 ggaacagttt tacgaagcag gcggcaaaag ctaccgctac atcccctgcc tcaacgacaa
    12661 ccccgactgg atagacgcac tcgtcgcact tgccgaagaa aaccttggcg gctggcgttg
    12721 aaactgtttg acccatgtct aaaatgccgt ctgaacgccg tgttcagacg gcattttccc
    12781 gctactttag cgtatgatgg catctatgcc ggacaacaac atcaagtgca accttactac
    12841 cgattcggca aaaaaatctt tcacccgcta cgcaaaatca acaacaaggt ttcaaacatt
    12901 aaggaaacac caatgaacac aacccgactg ccgaccgccc tcgtcttggg ctgcctctgc
    12961 gccgccgctt ctgccgccga caacagcatc atgacaaaag ggcaaaaagt gtacgaatcc
    13021 aactgcgtcg cctgccacgg caaaaagggc gaaggccgcg gaaccatgtt tccgccgctc
    13081 taccgctccg acttcatcat gaaaaaaccg caggtgctgc tgcacagcat ggtcaaaggc
    13141 atcaacggta caatcaaagt caacggcaaa acctacaacg gattcatgcc cgcaaccgcc
    13201 atcagcgatg cggacattgc cgccgtcgcc acttatatca tgaacgcctt tgacaacggc
    13261 ggcggaagcg ttaccgaaaa agacgtaaaa caggcaaaag gcaaaaaaaa ctaaacagac
    13321 aaaatgccgt ctgaaaccgg caatccggct tcagacggca ttcaaatcaa acctttctaa
    13381 cgcggtactt tcagccccat agacccgata ttgccgtccc cgtcaacctc cttcgcggtc
    13441 agcataaagc cgccgatgtc aatacggccg cactcgaccg gctcctgact gtcggaacgc
    13501 ttatcgaaaa gctcggcaag gctcaaaccc tcttcgcccg cttccagcct caaaccgtaa
    13561 gcaagtgcca aatcacccga acgtgctgcc ggcaaaacga caaactcacc gaagaaatca
    13621 aaatactcac ggacgctaat acccgtctcg gtaaagtatt tcgccatttt atagtgaact
    13681 aaatttaaac cagtacggcg ttgcctcgcc ttagctcaaa gagaacgatt ctctaaggtg
    13741 ctgaagcacc aagtgaatcg gttccgtact atttgtactg tctgcggctc gccgccttgt
    13801 cctgattttt gttaatccac tatatcgacc ttgccgtcgg gcaggatgta ccacgccaaa
    13861 tccccgcctg aagcacggtg tcggactgca tttcgattcg gctatacgcc ttttcacgca
    13921 ggctgtaatt gaatttccac aaaccgccga acactgccgg cggacgcgcg accagcatca
    13981 ggaacgccgc aatcgccaag gcttccgccg ccccgtccaa cacgccggcg ggagaaacca
    14041 gcagcaaagg cattcccaaa cgtgcgggta aagtggtcga aaccacgctc agaaacaaca
    14101 gtgcgccacc cggcaggaac agactgccca tccaatccac gctaacgatt ctcccttaaa
    14161 attcatgaaa ttaaaatcga aagactgtaa cacggcattt tcttttcacg aaactttact
    14221 tcacgtccgc cacagcgttc agacggcatt ttcctgtttc atgccgcctg aaaccgccca
    14281 aatccgcgtt ctcctatata atgtcggact ttgcgccgca tttcaggatt ctttaatggc
    14341 atttgcctca ctatttaccc tgccggacga catcaccgcc gttttggacg atgttgccct
    14401 gatgaccaaa gccgccgcaa agaaaaccgc cggcgtggtc ggcgacgatt tggcacccaa
    14461 tgccaaccgg gttacgggcg tatcggcaga acgcgagttg ccgattgttt ggtcgatggc
    14521 gaaaggttct ttttccaaca agccggtttt ggtgcctgcg gccctgctgc tttccgcctt
    14581 cctgccgcaa ctcattacgc cgcttttgac ggcaggcggc atttatctgt gctttgacgg
    14641 cgtagaaaag ctgctgcaca agtttctgca ccgacatgac gcgcatgctc gtaatggcgg
    14701 caatcggcat cggcatgact gttttggtgt acggaatcgt tgccgtcatc gtcaaactcg
    14761 acaacttagg catgctgctg atgcgccgcc cacaaacctt ttcgcgcagt ttggggcaaa
    14821 tgctgactgc ctttatgcct tgctttatgc gcggtttgag cgtggtcggc acgcttgcca
    14881 tgtttcttgt cggcggcgta ctggtcgccc acaacctcgg ccttctgcac gatttcctgc
    14941 acgcgcaaca ctgggacgct ggctgggcgg agtacttcgc caacctcgtt gtcgggctgc
    15001 tttccggttc gattgcctgc gcccccgcct tgccgctgat gaatcgtttc ggcaggcatt
    15061 gatttctttt tcaaataccg atgccgtttg aaagatgttc agacggtatc ttccgaacag
    15121 acagatgaat atgttttcca aactggacaa atactggcag caccccgccc tctactggcc
    15181 tttgctcatc ctttttgccg ccgccacccc ctttaccttc gcaccctact accacttttg
    15241 gctgatgccc ttgattttcg gtgccttcgt ccgcctcatc gaactgcgtc cgcgttttgc
    15301 tgtctcttcc gcctacctgt tcagcctgac cgcatacacg acacagttct actggataca
    15361 caccgccctg cacgacgttt ccggcctgcc cgacctctat gccgtaccgc tgactttcct
    15421 actccccgcc taccttgccc tttatccggc actgtgtttc tggctgtgga aaaaatttac
    15481 cctgcctcgg ggcataaaaa tcggtttggt actgcccatc ctgtggacac tgaccgagtt
    15541 tgcccgcgaa cgtttcctga ccggattcgg ctggggcgca atcggctact cccaaatcac
    15601 cccggacagc ccgctcgccg gctttgcccc attgggcggc atccacatgg ttacactggc
    15661 aaccgccttt ctcggtgtct ggctggtttt ggcgagtgat aacaccgcac gttcgggcaa
    15721 acgcctgctt ccaattatcc tgattgccgc cctgcttgcc gcaggctaca ccgcccgaca
    15781 aaccgacttc acccgccccg acggcagccg cagcaccgtc gccctgcttc aaggcaacat
    15841 cgaccaaacc ctcaaatggc gtgaagacca agtcatcccg accatacaga aatattacga
    15901 acaggtcggc aaaaccactg ccgacatcgt catcctgccc gaaaccgcca tccccgttat
    15961 gcgccaaaac ctgccggaaa acatactggc aaaatttgcc gaacaggcgc aaaacaacgg
    16021 cagcgcgctc gccgtcggca tcagccaata cacttcggac ggcaacggtt acgaaaacgc
    16081 cgtcatcaac ctgaccggtt atcaggaaaa caatcaggac ggcatcccct actacgccaa
    16141 aaaccacctc gtccccttcg gcgaatacaa accgctgccc ttcctgacca cgccgcttta
    16201 caaaatgatg aatatgcccc tttccgactt ccgcaaaggc ggcggtaagc aatccgccct
    16261 gctgatgaaa aaccaaaaaa tcgccttcaa catctgttac gaagacggat tcggcgacga
    16321 actgattgcc gccgccaaag atgccaccct gcttgccaat gccagcaata tggcgtggta
    16381 cggaaaatcc aacgccatgt accagcacct ccaacaatcg caggcgcggg ctatggaact
    16441 cggacgctat atggtccgtg ccaccaacac cggcgcaacc gccatcatct cccccaaagg
    16501 caacatcatc gcccaagccc aacccgatac ggaaaccgta ttggaaggac acatcaaagg
    16561 ctatgtcggc gaaacgccct atatgaaaac cggcagttca tggtggttga tgggcatatt
    16621 gaccctagcc gcactgattc ttttcatctt ccgaaacaaa gaacactgat acctgcacag
    16681 cccgtccgga cgggctgtct tttttcaaaa cggctattta catacaatta cgtatgtaat
    16741 ataattctga aatcgaattg agccatcagg tttacaaaat caatcaaacc tgccttacaa
    16801 aattttcctg tctttcaaac cttagcgcat atctcctgcc aaacatacaa aatacaagcc
    16861 aagcagtgat atactgcatc ccaacacagc aaaccgccga tacgcagttt cagccgaaag
    16921 gaaatgcccc aaatgaataa cgctttcgca ttacccgcca tccaaagcgg caacggcagc
    16981 ctcgaacaat acatccacac cgtcaacagc atcccgatgc tgtcccagga agaagaaacc
    17041 cgcctcgccg aacgccggat aaagggcgac ctcaacgccg ccaaacaact catcctgtcc
    17101 cacctgcgcg tcgtcgtttc catcgcgcgc ggctatgacg gctacgggct gaatcaggca
    17161 gacctgattc aggaaggcaa tatcggactg atgaaggcgg tcaaacgcta cgagcccggt
    17221 agaggcgcgc gtctgttttc atttgccgta cactggatta aagccgaaat ccacgagttt
    17281 attttgagaa actggcgttt ggttcgcgtt gccaccacca aaccgcaacg caagctgttt
    17341 ttcaatttac gcagtatgcg taaaaacctc aacgccctgt ctcccaaaga ggcacaagac
    17401 atcgccgacg atttgggtgt caaactttcc gaagttctgg aaatggaaca gcgcatgacg
    17461 ggacacgaca tcgccatcat ggcagacaac agcgacgacg aggacagttt cgcccccatc
    17521 gactggcttg ccgaccacga ttccgaaccg agccggcaac tatcgaaaca ggcgcattac
    17581 gccctgcaaa cagaaggttt acaaaacgct ttggcgcaac tggatgacag gagccgccgt
    17641 attgtggaaa gccgctggct tcaagacgac ggcgggctga cgctgcacca gcttgccgcc
    17701 gaatacggcg tatctgccga acgcatccgc caaatcgaag caaaagccat gcagaaactg
    17761 cgtggtttcc tgaccgaaga agccgaagcg gtttgaaata tacgcaataa aatacccgac
    17821 aaattgtttt gtcgggtatt ttatttggta aacatcaatg cggtttgtgc gtcgtgccgt
    17881 acacgatttt atccgtccaa accatcgcaa tcgccgaaat caaaaagcag acatgcacca
    17941 gacactgccg catcagctgc ttttccgaca gattggcgga attgatatag tggattaaca
    18001 aaaatcagga caaggcggcg aagccgcaga cagtacaaat cgtacggaac cgattcactt
    18061 ggtgcttcag caccttagag aatcgttctc tttgagctaa ggcgaggcaa cgccgtactg
    18121 gttttggtta atccactata catttccctt ccttgcagca acaaaagagc gtgattccaa
    18181 tctgccgctg caaaaccttc aatttttcac acccgaaaac gcttgccgcc atacagatgt
    18241 gatatattga ttccatttta acgggcttcg gagaacgaca tgagcagcgg aaatatccac
    18301 atccacagca tgaccggctt tgccaacgcg gcggcagagt gcggcagcaa acgcatcaac
    18361 ctcgacatcc gcgccgtcaa ccaccgcttt ttggacattc aaatcaggat gccggatgat
    18421 ttgcgctatt tggaaagcgg tatccgcgag aaaatttcat cccatatcgc gcgcggcaaa
    18481 gtcgaatgca aaatccaaat tcaagatacg gaaaacagca gacagtcctt ggaactcaac
    18541 tcggatttgg tgaaccagct tgccgaaatc aacaaaaacc tccgcaagca tcacgatttg
    18601 gcaaaactgg gcgttgccga catcctgcgt ttccccggcg tattggcaag ccaaagggaa
    18661 aatacggagg aattggcaaa aagcattacc gaactgaccg aaaaagcgtt aaaagacttt
    18721 actgccgcac gccggcgcga agggaaaaaa ttgggcgagc acctgttaca acgcctcgaa
    18781 agcatggaag aaatcataga tgcattgagc gaactctttc ctaccctgct ggaaacacat
    18841 aaagaaaaaa tccgcgcccg cctcgtcgaa gcagtcggcg acatcaataa tgacaggctg
    18901 caacaggaat ttgccctctt tattcaaaaa tccgacatcg acgaagaatt cagccgcctg
    18961 cgcacgcata tcgacgaagt acgccgcatc gttaccgaac acaaaggcag cagcggaaaa
    19021 cgcttggatt tcctgatgca ggaattaaac cgcgaagcca acactttggg cagcaaatcc
    19081 attgccgccg aatgcaccca agcctcggtc gaactgaaag tcttaatcga gcagatgcgg
    19141 gaacaagtgc agaatatcga ataatcggtt tccccgataa ccaaatgccg tctgaaagcc
    19201 ctttcagacg gcattttttc aggttgaaac ctttgcggta taaaggctta aggctttcct
    19261 ttgaccgcca ctaatcttgt tcctgcaaga aaatcataca gaaactgccg atcgggattc
    19321 agcagggcga acccccacgg taaaatcagc caaatcaatg ccgcgccggc cgcgcccttg
    19381 ggcggaatgc cgaggaagtg gcgcaatccg gcataggcta acatagggat aaatacgata
    19441 aatatgcacg cccaaataaa gcgcaggcgc agcaggtaca aagacggctg tatgccgtta
    19501 aggtcgcaca agccgatttt ccatgtcctc atcgccaagg tctgcccctg accatgccag
    19561 ttggcgcgga aataaagcca ccatgctccc attatcagga tacttgttac caatgcagaa
    19621 accgcgatag aaacgggatt cagaaaaatg gcggcaatac cggcaaacaa tgctgccaaa
    19681 caggttgccg caccgaccag cagcatttcg tacagcatgg cggcaaagcg gcgtttgagc
    19741 ggggcggttt tcagtgtcat catcttttca atcagaatat gccgtctgaa acgccaacag
    19801 gcttcagacg gcatttatgc aaagatgcct tgcggcggtt aacggtgcgg acgtttctga
    19861 ccgcgcgact gttttgccgc catttgattg atttcctgac gtgtcgggcg ttttttgaac
    19921 atagcgtgcg cctcgtccac cgaacatttt tgcgacaggc agatcagggt aatcgcatct
    19981 ttctggtgtt gtccgccgct gtggtacata cggcgcaggt ttgcctcgtt gattctgcct
    20041 ttttcgggat cgatgtcgaa ttttttcagg cgttcgataa actggcgttg ctgtcggcgg
    20101 gatgtccaaa caaaaccgcc cgcagcggca gcgacaatga cggctgcaag caggatggca
    20161 agcggccagg aatcgacaat caatacgata atgaggctta aaacggcggt ggtcagtaaa
    20221 atcaggccgc ccaagcgcag tttggtctta ttgtccatag ggttaatgtt cctttattga
    20281 ggtggtcgtg ccgtctgaaa tgttttcgga cggattggtg aatacttttc aggattaacg
    20341 gtattttaca gtattttcgg attttgggga ttaccgcttt attccgccag cgacacgaca
    20401 agccgtttga ataccgtcca tgcgtcgccg tcttccgcgc ctttgatgat tcggtcgatt
    20461 tgggcgcagg ttttgagcgc gtcaagcagg cggacgacgg aaatccgctt gaccgcaagc
    20521 ggcgcgagcg tctgcttgtc gccccaaagt ctgagactgt tgcgtacgga ttggacaccc
    20581 tgcccctgtt tcaggacagc ggcaagccga atcagcgtcc gcacgtcttc ggcaaccgcc
    20641 cacagaagca gtaccggttc ttcgccttcc tcctgcaatc cgtccaacaa cctgcatacg
    20701 cgcgggacat cgcccttcat ccatgcgccg gcaagctgaa aaacgtcaaa gcgggcaaca
    20761 ttggcaacgg cggtttgcgc ctcatcgata ttgacggtat gccctttcgg atacagcagc
    20821 gcgagcttgt cgatttcctg acgtgccgcc aacagattgc cttccacgcg ctcggcaaac
    20881 agtgccaatg cgtctgcccc gatacccaaa ccgattttgt ccagccgtcc gcgtatccat
    20941 tggggcaaag ccgccgcgcc gaccggtttg gcttcccaca cttccccctt tgccgccaat
    21001 gcggcaaacc atttggactg gagctgggtt ttctccagtt tgggcagtaa aaccagcgtt
    21061 accgtatctt ccggcaggcg ggcggcaaaa tcctgcaacg cctcgccgcc ggttttgccg
    21121 ggcttgccgt tagggatatg cagttccaac agcttcaaat cggcaaacag acccgcactg
    21181 cctgcggttt gcagcagctc gttccaatcg aaagcattgt ctgccgtata aacttcccga
    21241 ttaaggtaac cttgtttctt cgccgccgcc ctcaatgcgt ccaatgcctc gatacgcaac
    21301 agttcttcct cgccgtggat gacgtacagg ggtttcaaag gcgcgtccgt atcaatgcgt
    21361 ccgatatgtg ccgccacgtc attccgcctt cagaaaggtc aggcggcgga caatctgttc
    21421 ggcggcatcc tgccgcattt ccgcccacaa tgccgcttcc tcttcctgtt tgcccaagat
    21481 ctcgttgtcg gcataagcaa ggacgcggcg gacggacacg gtcatcggtt tgccgaccgg
    21541 ctcgccgcgt ttcaatacct gcgcttcaac cgtcaatatc aaaagatatt cgttgatgac
    21601 tgccgcacgg gtaacggtgt aggtttcctt gttttgggaa acgctgtcta tacgcagggt
    21661 catctgcgcg ccggcagcat cgtccaccct gcccgaagcc tgatacagcg ctgtttccaa
    21721 aggaaaccgc aatgcctgtc cgccttcgat gtgccagctc cggtaggtca gcggcggaga
    21781 aatgccgtct gcacctttca ggtggaaacc gcacgcgccc agcatcagca ctgcggcagt
    21841 aagaaacagt ttgttcatgg cttgcctttc tcaaaagcac aaagtcggta gattatatca
    21901 gcggcgtgtt cagacggcat tgccgtccag ccaaatcagg ctcgccatac gccctgtcgc
    21961 tccgtcgcgg cggtaggaaa agaaagtatc ccgttccaaa accgtacaat gcgtgccgcc
    22021 gtatacgccg cccacgcctt cgcgcttcag aatcaggcgg gcgagcgcgt aaaggtcggc
    22081 aaggaatttg ccgccgccta tgccttcaaa tgcggcggcg gcttcgggca tgggcgtgca
    22141 gaacgcatca aacacatcct gtccgacttc aaacgcatcc gcactgatgg cggggccgag
    22201 atacgccatc atttcgacag gcggaacctt catcgcagca atggtgtttt gcaatacgcc
    22261 gcccgccaaa ccgcgccagc ccgcgtgtgc ggcggcaacc gccgtacccg ccctgtcgca
    22321 aaatagaacg ggcagacagt ctgcggtcat cacggcacag gcggccttgc ccgtgtcgtc
    22381 cacggaagcg tcggcatcgg gcgtgccgcc taacgcttcg gcagcgttga cgacgatggt
    22441 gctgtggatt tgattgaggt aggcaacggg caatccgacc tgctgttgca cgatttcgcg
    22501 gttgcggcgc acggcttcgg gattgtcgcc gacgtgcgta ccgaggttca aactctgata
    22561 cgcaccttgg ctcacgccgc cgttgcgcgt ggtaatcagg gttttcacat tggcgggcgc
    22621 gggccaatcg gcggtcagga agtttttgcc tttcggggca agatttaggg tttctgtgat
    22681 ggttttcatt ggatattgga ataggtgtgt ggcggaaagg gttgattaac tgccttcggg
    22741 gcaaatggat gtttgttttt tcgtcattcc cgcacaggcg ggaattcgga gattcgggat
    22801 tgttttcaaa cgttcgggtt cggattcttg ccggtgcagg aatgatgccc ttatatatag
    22861 tggattaaat ttaaatcagg acaaggcgac gaagccgcag acagtacaaa tagtacggca
    22921 aggcgaggca acgccgtact ggtttaaatt taatccacta tactttctcc gagctttata
    22981 tgtttcaaca gaggacggca catcaagcac cgcactgcgt gttgcccgaa cgagactacc
    23041 ctccgattag attctatcgc tataaacaga tgggtttcaa ccgaaaagga atggggataa
    23101 agtccatttc cgacacctct cgggcgatgc cgtctgaaaa ccaatctcca ctttcagacg
    23161 gcattgttta ggcacggtca ttttgcaaat taaggttaag gcgtgtatgc ttgccttccc
    23221 ttaaaaacaa acacgcaacg cattattatg aatatcctca gtaaaatcag cagctttatc
    23281 ggaaaaacat tttccctctg ggccgcgctc tttgccgccg ccgctttttt cgcgcccgac
    23341 accttcaaat gggcggggcc ttatattcct tggctgttgg gcattattat gttcggtatg
    23401 ggtttgacgc tcaaaccttc cgacttcgat attttgttca aacatcccaa agccgtcatc
    23461 atcggcgtaa tcgcacaatt cgccattatg ccggcaaccg cctggctgct gtccaaactg
    23521 ttgaacctgc ctgccgaaat cgcggtcggc gtgattttgg tcggctgctg cccgggcggt
    23581 acggcttcca atgtgatggc ctatctggcg cgcggcaatg tggctttgtc ggttgccgtt
    23641 acgtctgttt ccaccctgat ttccccattg ctgactcccg ccatcttcct gatgcttgcc
    23701 ggtgaaatgc tggaaatcca agcggccggt atgttgatgt ccatcgtcaa aatggttttg
    23761 ctccccattg ttttgggttt gattgtccat aaggttttgg gcagtaaaac cgaaaagctg
    23821 accgatgcgc tgccgctggt ttccgttgcc gccatcgtgc tgattatcgg cgcggttgtt
    23881 ggggcaagca aaggcaagat tatggaaagc ggcctgctga tttttgcggt tgtcgtactc
    23941 cacaacggca tcggctacct gctcggcttc tttgccgcca aatggaccgg cctgccttat
    24001 gatgcacaaa aaacgctggc catcgaagtc ggtatgcaaa actcgggcct ggccgccgcg
    24061 cttgccgccg cacactttgc cgctgcgccg gtcgttgccg ttccgggcgc attgttcagc
    24121 gtgtggcaca atatctccgg ctcgctgctg gcaacttatt gggcggccaa agccggtaaa
    24181 cataaaaaac cctaaacgcc tttcatcata atgccgtctg aacggggcaa acgaaaccgg
    24241 cggtttccgc ccgacccctt cagacggcct ttgtttgaaa tcggcaggga cgattgtccg
    24301 gctgctccga ttcggctgcc tgcgttcgcc ccgcctttca agccgcctca ctcccttaca
    24361 taaaccactt cgacatcgta gtcgtcttcg ttccaatcgt catcgtcgtc cgcgccgaat
    24421 ttgtcctgcc attcctcttc attgctcaaa gacgaatcca aaccggcttc aagacggagg
    24481 acagacaaca aatgatatat gtcgtccgga atcggtgctt caaacgaaac ggtttcgccg
    24541 gttttcggat gagtgaaact taagcggtag gcgtgcaatg cctgacgcgc acccaaactt
    24601 ttaacggctt ctttcaccgt gtcgccgcac ggatggcgcg ggttgccgta aaccgggtcg
    24661 gcggcaagcg gatggttggc ctcacgcata tggacgcgga tttggtgcgt cctgcctgtt
    24721 tcgagcgagc attcgatata gctgtgcgcc agatagcgtt ccaacacttt gacgtgggta
    24781 acggctggtt tgccgccgaa tttgacgact gccattttca ggcggttgtg cggatcgcgt
    24841 ccgatttggg tttcgatttt accgtcaaag ggaacgatgc cgttggcgac ggcgcggtaa
    24901 atgcgtttga ccgtgcgctc ttgaagctgt tgcacgaggg aattttgcgc cggcagggtt
    24961 ttggcaacca ccatcagccc gctggtttct ttgtccaaac ggtgtacgat gcctgcacga
    25021 ggtacttggc tcaattcggg acagtgcgcc aagaggccgt tgagcagcgt tcccgtccag
    25081 ttgccggccg ccggatgcac caccagtccg gccggtttgt tgacgacgat gacggtatcg
    25141 tcttcgtaaa caatatccaa agccataggc tctggaacaa acgccagatt ttcctcactc
    25201 ggacggacgg ttacacaaat ttgctcgccg cctatcattt tgtctttggg ttgcgaaggt
    25261 ttatcgttta caataaccgc gccttcttta atccatgatg tcaggcggct gcgcgagtag
    25321 tcgggcagaa gtttcgccaa caccgcatcc aaccgcccgc cggcaagctc gagcggaacg
    25381 gtcagaccga tacggttttc agtttcggaa gctgacgcaa agtctgaatc gtcgctataa
    25441 tcggattcat tatcaaagga agtattctgc atgaaaaaaa ttcttttaac ggtttcatta
    25501 ggtttggcac tgagtgcctg tgccactcaa ggtacggtcg ataaagatgc tcagattacc
    25561 caagattgga gtgtggagaa gctctatgcc gaagcccagg acgaattgaa cagcagcaat
    25621 tatacgcggg ctgtcaagtt atacgaaatc ttggaatcgc gcttccccac cagccgccat
    25681 gcccggcaat cccaactgga taccgcatac gcctattata aagacgatga aaaagacaag
    25741 gctctggcgg caatcgaacg cttccgccgc ctccatccgc agcatccgaa tatggattac
    25801 gcgctgtatc tgcgcggctt ggtgctgttc aacgaagacc agtccttctt gaacaaactg
    25861 gcctcgcaag actggtccga ccgcgacccg aaagccaacc gcgaagcgta ccaggcgttt
    25921 gcggaactcg tccaacgctt cccgaacagc aaatacgccg ccgatgcaac cgcacgcatg
    25981 gtcaaactgg tcgatgcact gggcggcaat gaaatgtcgg tggcgcgtta ctacatgaaa
    26041 cgcggcgcat atatcgccgc cgccaaccgc gcccaaaaaa ttatcggcag ctatcaaaat
    26101 acacgctatg tcgaagaatc gctcgccata ttggaacttg cctaccaaaa actcggcaaa
    26161 ccgcagcttg ccgccgatac gcgccgcgtg ttggaaacca acttcccgaa aagcccgttt
    26221 ttgacgcacg cctggcagcc cgacgatatg ccctggtggc gttactggca ttaagcccat
    26281 cttcgtaatg ccgtctgaag ccgtttcaga cggcatttta tgtttcaaac ctcattcaaa
    26341 cggttttttc tgccaataga atttataccc tctcaaacgt tgagccttca cgccgccgcg
    26401 tcccaagccg aattgcagtg cgcccgacaa atcggtacgc agcagtttga tgccgtgtgc
    26461 gcggacacgg ttctgcaccg cttcggtcgg atgtttgtag gcgttggcat aaccgcttga
    26521 agcaacggca tattcgggcg agacggcatt gaggaacacg cccgacgagg acgtattgct
    26581 gccgtgatgt cccaaaacca aaacctggct gtacaggttg cctccatact tgccgaccag
    26641 gctttcctcg cccttcgtat ccaaatcgcc cgttaccagc agtgccgcac cgcccgccac
    26701 aacacgcaaa acacaacttt tcccattatc atcgatgttt ttgcgttcag acggcatcaa
    26761 aaactcaaaa tccacgccgt cccattgcca acgctgttcc gcacaatgcc gcgccccctc
    26821 ataaaattcc ggctgtccgg cataaatccc gccgttcggt atcttgccga ctgcctgaaa
    26881 accgccgtcg tggtcgctgt cgtgatgcga cagaaccagc ttgtccaaac ggcggacacc
    26941 cgccgcattc aaactcggca caatccccat ctgcgccgcc gctgccgttc cggtgtcaaa
    27001 caaaagatga tgatttgccg tctgaaccga caccgacaaa ccctgccccg catcccaaac
    27061 cgtaaccgca acctcatttt ccggcacgcc gggtgaacgg taaaacacaa accctgccaa
    27121 cagcaacacc gcccacggac gcaaacccaa gccgcgcggc agcagcaaca gcaaagcggc
    27181 acacaccgcc aacaccaaca gcggcaaagg tgcggaggca acggcaaact cgggcgacac
    27241 atcggcaagc cacaccaaaa accgcaaagt atattccgcc aaaaatgccc ccaactgttg
    27301 caaaggcgca aacggcacga ccgaacccag caacgccagc ggcgtcaata cccaagaaaa
    27361 ccacggaatt gccaccgcat tgaccaaagg gctgaccaaa ggcagcgaag caaacagata
    27421 accgagcaaa accagcgaca acaccgaagc cgcccactgc ccgcgcaaag cagtttgccg
    27481 ttttccctcg tgcaaacgcc ccgagcacgc ccatatcagg gccgccacca aaccgaaaga
    27541 cagccaagtc cccacaccca agaccgccga cgggtcgaac agcagcaccg ccgccaacgc
    27601 ctgccaccac gtcgcccacg ccgacaatct tcccctgcgc caagcccacg caaacgccgc
    27661 caacatcaaa acgctgcgct gcgtcggcac ggaaaaaccg gcaagcagcg cgtaaaacag
    27721 cgcgcctgca caccccgccg ccaaaaccca cgcgcgcggc cgggcaggaa ggcgcgggga
    27781 acaggcaagc agccgcttcg ccagccacgc aaacattacc gccaccatcg taacgtgcaa
    27841 acccgaaata ctgaccaaat gcgtcagccc caacggccgg aacgcctgcc acaattcggg
    27901 gcgcaatgcc gactgttcgc ccacgctcaa cgcgcgcatc agcccgatgc cgtctgaaag
    27961 cccgccgtcc gcatccgcct gctgccaatt acggctgatg cggctgcgcc aaaccgcaat
    28021 cccccaaccg cttccgccat gcagcaaaac cctgtccgca ccgaccgtcc ccgcgccgcc
    28081 tattccgttg gataatgccc acgcctcacg gttcaaaccg cgcaggttca actccccgac
    28141 gacagggtgc acacgtgccg ttatccgcca tctgctcccg accgcccatt cgcgccgttt
    28201 gtagtccgac agcagcaaat caaacgtccg accaccgctg tccacagcct ttgccgcaaa
    28261 ctgcacacgc cgcccgtccg acctcggcat atccgccact tccaccgtca aaggcacgcc
    28321 tgaaacggct tctgcccacc attgggaaga caatgccgcc tccgtcctga atacgccgta
    28381 agccgcgccc gccaacacgc acagcatcag accggcaaac gcaaaacgcc ttgcaaacac
    28441 agcaaaaacc gcaaaagccg ccagccaaaa cagccaatgc ggcacgaccg gcagcgcgaa
    28501 cgaagccgcc gcaccgacaa cccaacacgg caaaaaccaa cgacggaaca cgtctcccca
    28561 ccccagatat ttcaaaaata aacggataat aaagcaaatc cgaaaaaccg tcataacaag
    28621 atttgaaaat gatatagtgg tttaaattta aatcaggaca aggcgacgaa gccgcagaca
    28681 gtacaagcag tacgacaagg cgaggcaacg ctgtactggt ttttgttaaa ccactataag
    28741 aatgcaaacg aaaagcctca gtattatccg agacaacggc aaactttcca tcgtcattcc
    28801 cgcacaagcg ggaatccaaa aacaaaaagc cgcagaaatt taacggaaga accaaacccc
    28861 gaaaaccggc tccccgcctt cgcttgaata acagaacaaa ggaatcagta ttatccgaga
    28921 caaccgcaaa ctttccatcg tcattcccgc acaagcggga atccaaactt gtccgcacgg
    28981 aaacttatcg gataaaacgg ttt
//
LOCUS       DAXISH010000019        28901 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.019, whole genome shotgun sequence.
ACCESSION   DAXISH010000019 DAXISH010000000
VERSION     DAXISH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 28901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28901
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.019"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..1042
                     /locus_tag="ACFOV4_000856"
     CDS             <1..1042
                     /locus_tag="ACFOV4_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="polyamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7618897.1"
                     /translation="EAEQSGKLNIYNWSDYVDPETVAAFEKETGIKTRSDYYDSNETL
                     EAKVLTGKSGYDLTAPSIANVGRQIKAGAYQKIDKAQIPHYGNIDKDLLKMMEAVDPG
                     NEYAVPYFWGINTLAINTRQVQKALGTDKLPENEWDLVFNPEYTAKLKSCGISYFDSA
                     IEQIPLALHYLGKDPNSENPEDIKAAVDMMKAVRGDVKRFSSSGYIDDMAAGNLCAAI
                     GYGGDLNIAKTRAEEAANGVEIKVLTPKTGVGVWVDSFMIPRDAQNVANAHRYIDYTL
                     RPEVAAKNGSFVTYAPASRPARELMDEKYTSDASIFPNKELMEKSFIVSPKSAESAKL
                     GVKLWQGLKAGK"
     gene            1177..1443
                     /locus_tag="ACFOV4_000857"
     CDS             1177..1443
                     /locus_tag="ACFOV4_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFC7618898.1"
                     /translation="MNLSIVVPIYNVESYLEACLSSIEPILSNENVELILVNDGSKDG
                     SEDICYKYIDKISNNKQQTTNNKQQTTNNKQQTPDTKYQIYISG"
     gene            1451..2209
                     /locus_tag="ACFOV4_000858"
     CDS             1451..2209
                     /locus_tag="ACFOV4_000858"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC7618899.1"
                     /translation="MSEARNTGIKNSNGKYIVFIDSDDFINCQVLLDFLSKDDIDMPD
                     VVFLNAVKYDKGSVSYFGEDYQPEKILNQSKVEVLKGLCRFRKFPGSAWNKIIKRELI
                     IKEKLFFEKGIYSEDVEWSMRLFNAATTFSYLDGCYYYYRQGREDSITGTVSEKSIKS
                     LLYILEKNAEMEFNRDISSYLYSFLSYEYLVLLFIMTSKNIACDADIKRRAYHLRFML
                     LKSNKLIYKLIFPIITLFGVDITGRILKAIRGNI"
     gene            2250..2780
                     /locus_tag="ACFOV4_000859"
     CDS             2250..2780
                     /locus_tag="ACFOV4_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFC7618900.1"
                     /translation="MNAIRTFQNRTPEIHESCMIDEACVVIGEVSLAEDVSVWPCAVL
                     RGDVNSITVGARSNIQDGSVLHVSHKTAAKPEGSPLVIGEDVTVGHKVMLHGCRIGNR
                     VLVGMGTTVLDDAVIEDEVMIGAGSLVPPRKRLEGGYLYVGSPVRQVRVLTDEEKAFL
                     KYSAAHYVKLSKQYGM"
     gene            complement(2814..2930)
                     /locus_tag="ACFOV4_000860"
     CDS             complement(2814..2930)
                     /locus_tag="ACFOV4_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor domain protein"
                     /protein_id="HFC7618901.1"
                     /translation="MPSEPEKRLSDGIFACNPNAVGQNQGASDTVIGCVPSA"
     gene            complement(2949..3137)
                     /locus_tag="ACFOV4_000861"
     CDS             complement(2949..3137)
                     /locus_tag="ACFOV4_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor"
                     /protein_id="HFC7618902.1"
                     /translation="MPSKPEKRASDGIFACNSNADGQNQGASDTAIGHPVRMNLGLTQ
                     ERWPDIVFHETREHSVKL"
     gene            complement(3156..4751)
                     /locus_tag="ACFOV4_000862"
     CDS             complement(3156..4751)
                     /locus_tag="ACFOV4_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007342770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFC7618903.1"
                     /translation="MSQEILDQVRRRRTFAIISHPDAGKTTLTEKLLLFSGAIQSAGT
                     VKGKKTGKFATSDWMDIEKQRGISVASSVMQFDYKDHTVNLLDTPGHQDFSEDTYRVL
                     TAVDSALMVIDAAKGVEAQTIKLLNVCRLRNTPIVTFMNKYDREVRDSLELLDEVENI
                     LQIRCAPVTWPIGMGKNFKGVYHILNDEIYLFEAGGERLPHEFDIIKGIDNPELEQRF
                     PLEIQQLRDEIELVQAASNEFNLDEFLAGELTPVFFGSAINNFGIQEILNSLIDWTPA
                     PKPRDATVRMVEPDEPKFSGFIFKIQANMDPKHRDRIAFLRVCSGRFERGMKMKHLRI
                     NREIAASSVVTFMSHDRELVEEAYAGDIIGIPNHGNIQIGDSFSEGEQLAFTGIPFFA
                     PELFRSVRIKNPLKIKQLQKGLQQLGEEGAVQVFKPMSGADLILGAVGVLQFEVVTSR
                     LANEYGVEAVFDSASIWSARWVSCDDKKKLAEFEKANAGNLAIDAGGNLAYLAPNRVN
                     LGLTQERWPDIVFHETREHSVKL"
     gene            complement(4858..5253)
                     /gene="hisI"
                     /locus_tag="ACFOV4_000863"
     CDS             complement(4858..5253)
                     /gene="hisI"
                     /locus_tag="ACFOV4_000863"
                     /EC_number="3.5.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="HFC7618904.1"
                     /translation="MDKNLLEAVKFDEKGLVCAIAQDAETKRVLMVAWMNAEALQKTV
                     ETGFAHYYSRSRQKQWMKGEESGHTQKVRELRLDCDGDAIVMLIAQNGGIACHTGRES
                     CFYKVWRGGAWETADAVLKDEKEIYGSTH"
     gene            complement(5284..6051)
                     /gene="hisF"
                     /locus_tag="ACFOV4_000864"
     CDS             complement(5284..6051)
                     /gene="hisF"
                     /locus_tag="ACFOV4_000864"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HFC7618905.1"
                     /translation="MALAKRIIPCLDVKDGRVVKGVNFIGLRDAGDPVEAAKRYNGEG
                     ADELTFLDITASSDNRDTILHIIEEVAGQVFIPLTVGGGVRTVADIRRLLNAGADKVS
                     INTAAVTRPDLIDEAAGFFGSQAIVAAVDAKAVNSENTRWEIFTHGGRNPTGLDAVEW
                     AIEMQKRGAGEILLTGMDRDGTKQGFNLPLTRAVAEAVDIPVIASGGVGNVRHLIEGI
                     TEGKADAVLAAGVFHFGEIAIREAKRAMREAGIEVRL"
     gene            complement(6064..6801)
                     /gene="hisA"
                     /locus_tag="ACFOV4_000865"
     CDS             complement(6064..6801)
                     /gene="hisA"
                     /locus_tag="ACFOV4_000865"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HFC7618906.1"
                     /translation="MLLIPAIDLKEGRCVRLKQGLMEEATVFSDSPAETALHWFKQGA
                     RRLHLVDLNGAFAGVPQNLPAIKDILAAVAKDIPVQLGGGIRDLKTIGQYLDLGLNDV
                     IIGTAAVKNPDFVREACKAFPGRIIVGLDAKDGMAAIDGWATVTGHHVIDLAKRFEDD
                     GVNSIIYTDIGRDGMMSGVNIDATVKLAQAVRIPVIASGGLTGLDDIRALCAAEKHGV
                     AGAITGRAIYEGSIDFAQAQQLADSLD"
     gene            complement(6834..7472)
                     /gene="hisH"
                     /locus_tag="ACFOV4_000866"
     CDS             complement(6834..7472)
                     /gene="hisH"
                     /locus_tag="ACFOV4_000866"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HFC7618907.1"
                     /translation="MQIAIIDYGMGNLHSVLKSVRTAGQLAGKNTEIFLSGDPERVSR
                     ADKVIFPGQGAMPDCMAALTRGGLDEAVKDALKNKPFFGICVGAQLLFDHSEEGNTDG
                     LGWFGGKVRRFERDLRDPQGYRLKVPHMGWNTVRQTQNHPLFKDIPQDTRFYFVHSYY
                     FAPENPETILGESDYPSPFACIVGKDNVFATQFHTEKSHDAGLTMLKNFLNW"
     gene            complement(7603..9105)
                     /gene="pta"
                     /locus_tag="ACFOV4_000867"
     CDS             complement(7603..9105)
                     /gene="pta"
                     /locus_tag="ACFOV4_000867"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFC7618908.1"
                     /translation="MAKVLIVPVSAGLDASAAAQAFAKALDAQIFQAVDATAETLLAQ
                     GKSDDWFDALVGKVAALDAANLVIEGIAPDADKIYLAGKNVELALSLDAAAVFAVRSD
                     NADADELANRLNLAKQFFAAAPGVLEGFVVDGAAASVAEAAAEKTGLTFFGSSDALKD
                     VSVLAGREAKRLSPAQFRYNLIDFARQADKRIVLPEGAEPRTVQAAAICHEKGIARCV
                     LLAKREEVEAVAKERGISLPDSLEIIDPASLVEQYVEPMCELRKSKGLTPEDARKQLQ
                     DTVVLGTMMMAQNDVDGLVSGAVHTTANTIRPALQLIKTAPGASLVSSVFFMLLPNQV
                     LVFGDCAVNPNPTAQQLADIAIQSADSAKAFGIDPKVAMISYSTVNSGSGPDVDTVIE
                     ATKLAREKRPDLAIDGPLQYDAATVPGVGKSKAPGSPVAGQATVLVFPDLNTGNCTYK
                     AVQRSANVLSVGPLLQGLRKPVNDLSRGALVEDIVFTIALTAVQAKQMEG"
     gene            complement(9290..10348)
                     /gene="fbpC"
                     /locus_tag="ACFOV4_000868"
     CDS             complement(9290..10348)
                     /gene="fbpC"
                     /locus_tag="ACFOV4_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter ATP-binding protein FbpC"
                     /protein_id="HFC7618909.1"
                     /translation="MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIVGASGCGKT
                     TLLRCLAGFEQPDFGEISLSGRTIFSKNTNLPVRERRLGYVVQEGVLFPHLTVYRNTA
                     YGLGNGKGKTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI
                     LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRIL
                     QTASPHELYRQPADLDAALFIGEGIVFPAALNADGTADCGLGRLPVQSGAPAGTRGTL
                     LIRPEQFSLHPHSAPTASIHAVVLKTTPKARHTEISLRVGQTVLTLNLPSAPTLSDGI
                     SAVLHLDGPALFFPGNTL"
     gene            complement(10369..11886)
                     /gene="fbpB"
                     /locus_tag="ACFOV4_000869"
     CDS             complement(10369..11886)
                     /gene="fbpB"
                     /locus_tag="ACFOV4_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease FbpB"
                     /protein_id="HFC7618910.1"
                     /translation="MSPKKIPIWLTGLILLIALPLTLPFLYVAMRSWQVGINRAVELL
                     FRPRMWDLLSNTLTMMAGVTLISIVLGIACALLFQRYRFFGKTFFQTAITLPLCIPAF
                     VSCFTWISLTFRVEGFWGTVMIMSLSSFPLAYLPVEAALKRISLSYEEVSLSLGKSRL
                     QTFFSAILPQLKPAIGSSVLLIALHMLVEFGAVSILNYPTFTTAIFQEYEMSYNNNTA
                     ALLSAVLMAVCGIVVFGESIFRDKAKIYHSGKGVARPYPVKTLKLPGQIGAIVFLSSL
                     LTLGIIIPFGVLIHWMMVGTSGTFALVSVFDAFIRSLSVSALGAILTILCALPLVWAS
                     VRYRNFLTVWIDRLPFLLHAVPGLVIALSLVYFSINYTPAVYQTFIVVILAYFMLYLP
                     MAQTTLRTSLEQLPKGMEQVGATLGRGHFFIFRTLVLPSILPGITAAFALVFLKLMKE
                     LTATLLLTTDDVHTLSTAVWEYTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK"
     gene            complement(11954..12949)
                     /gene="fbpA"
                     /locus_tag="ACFOV4_000870"
     CDS             complement(11954..12949)
                     /gene="fbpA"
                     /locus_tag="ACFOV4_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     FbpA"
                     /protein_id="HFC7618911.1"
                     /translation="MKTSIRYALLAAALTAATPALADITVYNGQHKEAAQAVADAFTR
                     ATGIKVKLNSAKGDQLAGQIKEEGSRSPADVFYSEQIPALATLSAANLLEPLPASTIN
                     ETRGKGVPVAAKKDWVALSGRSRVVVYDTRKLSEKDLEKSVLNYATPKWKNRIGYAPT
                     SGAFLEQVVAIVKLKGEAAALKWLKGLKEYGKPYAKNSVALQAVENGEIDAALINNYY
                     WHAFAREKGVQNVHTRLNFVRHRDPGALVTYSGAAVLKSSQNKDEAKKFVAFLASKEG
                     QRALTAVRAEYPLNPHVVSTFNLEPIAKLEAPQVSATTVSEKEHATRLLEQAGMK"
     gene            complement(13200..13670)
                     /locus_tag="ACFOV4_000871"
     CDS             complement(13200..13670)
                     /locus_tag="ACFOV4_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4375 domain-containing protein"
                     /protein_id="HFC7618912.1"
                     /translation="MTDTDTQADRFEQMMWQAVDKLFEQHDGKLESMDGWEQELVLIW
                     RAEADIGNGGILQFVCNWSFPAAEKTCSVLKKIGAIHSAMLIHRAADALDKEIRHLQS
                     EGKNLKEMWDITKHLDNKTASLPNSLDEQYWQDPDKLYLPGWQYYSGNPVQTLF"
     gene            complement(13727..15103)
                     /gene="argH"
                     /locus_tag="ACFOV4_000872"
     CDS             complement(13727..15103)
                     /gene="argH"
                     /locus_tag="ACFOV4_000872"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HFC7618913.1"
                     /translation="MHDKTWSGRFNEPVSELVKQYTASIGFDRRLAEWDIQGSLAHAQ
                     MLKETGVLDEGDLADIRRGMAEILEEIRSGKIEWSSDLEDVHMNIERRLTDKIGDAGK
                     RLHTGRSRNDQVATDIRLWLRDQITVIRSLIQSLQTALLDLAEQNAETVMPGFTHLQV
                     AQPVSFGHHMLAYVEMLGRDNERMADCRRRVNRMPLGAAALAGTTYPIRREITAELLG
                     FEQICQNSLDAVSDRDFAVEFTAAASLVMVHLSRLSEELILWMSPRFGFIDIADRFCT
                     GSSIMPQKKNPDVPELVRGKSGRVIGHLIGLITLMKSQPLAYNKDNQEDKEPLFDTAD
                     TLIDTLRIYADMMRGVTVKPDNMRAAVMQGFATATDLADYLVKKGMPFRDAHEVVAQA
                     VRHADQAGVDLSKLPLEVLQGFSDLIADDVYGVLTPEGSLNARNHLGGTAPEQVRFQV
                     KRWREMSA"
     gene            complement(15122..15991)
                     /gene="galU"
                     /locus_tag="ACFOV4_000873"
     CDS             complement(15122..15991)
                     /gene="galU"
                     /locus_tag="ACFOV4_000873"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFC7618914.1"
                     /translation="MKPIKKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEE
                     AVEAGCTEMVFVTGRNKRSIEDHFDKAYELETELEMRHKDKLLEHVRNILPPNITCLY
                     IRQAEALGLGHAVLCARAAIGDEPFAVILADDLIDAPKGALKQMVEVYGRSGNSILGV
                     ETVEASQTGSYGIVETEQLKQFQRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLT
                     GLPRGAGNEIQLTDGIAKLLDHEFVLAHPFEGTRYDCGSKLGYLEATVAYGLKHPETG
                     EPFRRLLEKYRTE"
     gene            complement(16019..16618)
                     /gene="rdgB"
                     /locus_tag="ACFOV4_000874"
     CDS             complement(16019..16618)
                     /gene="rdgB"
                     /locus_tag="ACFOV4_000874"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035870 - dITP diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0036222 - XTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RdgB/HAM1 family non-canonical purine NTP
                     pyrophosphatase"
                     /protein_id="HFC7618915.1"
                     /translation="MSEKPEKIVLASGNAGKLEEFGNLFKPYSITVLPQSAFGIPECP
                     EPYPTFVENALAKARHAAEYSGLPALADDSGICAAALNGAPGIHSARYAGDNPKSDTA
                     NNLKLAAELAGKTDKSCCYVCVLVFVRHKDDPRPIIAEGVWHGQWNGVPAGENGFGYD
                     PYFYLPGHGKTAAELDSEVKNRESHREQALADLIRKLAL"
     gene            complement(16611..16844)
                     /locus_tag="ACFOV4_000875"
     CDS             complement(16611..16844)
                     /locus_tag="ACFOV4_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NGO_0222 family membrane protein"
                     /protein_id="HFC7618916.1"
                     /translation="MNRRKIYLLSVALFTLAFMLLVLLGAYLLTVGSKAFAVASFLFA
                     FGALFGQIGSLALYLRHKSLRAAQSAAKENRYV"
     gene            complement(16952..17485)
                     /locus_tag="ACFOV4_000876"
     CDS             complement(16952..17485)
                     /locus_tag="ACFOV4_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HFC7618917.1"
                     /translation="MADFNQILTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLD
                     RVEPAIFAKPTNYGFIPQTLDEDGDELDVLLVTEQPLATGVFLEARVIGVMKFVDDGE
                     VDDKIVCVPADDRNNGNAYKTLSDLPQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAE
                     EAKKVIKESIERWNKQA"
     gene            complement(17587..18045)
                     /gene="nudB"
                     /locus_tag="ACFOV4_000877"
     CDS             complement(17587..18045)
                     /gene="nudB"
                     /locus_tag="ACFOV4_000877"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008828 - dATP diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0019177 - dihydroneopterin triphosphate
                     pyrophosphohydrolase activity [Evidence IEA];
                     GO_process: GO:0046656 - folic acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HFC7618918.1"
                     /translation="MPMAKPLKYPVSALVVLYSGDGGILLIERTHPEGFWQSVTGSLE
                     PGETVAQTARREVWEETGILLADGQLQDWHDSTVYEIYHHWRHRYPKGVFENREHLFS
                     AEIPRDTPIALQPEEHVSYGWFGLEEAAEKVFSPSNRRAILELGRFLGKR"
     gene            18256..18332
                     /locus_tag="ACFOV4_000878"
     tRNA            18256..18332
                     /locus_tag="ACFOV4_000878"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18290..18292,aa:Pro,seq:ggg)
     gene            18645..21044
                     /gene="mafB"
                     /locus_tag="ACFOV4_000879"
     CDS             18645..21044
                     /gene="mafB"
                     /locus_tag="ACFOV4_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 2"
                     /protein_id="HFC7618919.1"
                     /translation="MGISRKISLILSILAVCLPMHAHASDLANDSFIRQVLDRQHFEP
                     DGKYHLFGSRGELAERSGHIGLGNIQSHQLGNLMIQQAAIKGNIGYIVRFSDHGHEVH
                     SPFDNHASHSDSDEAGSPVDGFSLYRIHWDGYEHHPADGYDGPQGGGYPAPKGARDIY
                     SYDIKGVAQNIRLNLTDNRSTGQRLADRFHNTGSMLTQGVGDGFKRATRYSPELDRSG
                     NAAEAFNGTADIVKNIIGAAGEIVGAGDAVQGISEGSNIAVMHGLGLLSTENKMARIN
                     DLADMAQLKDYAAAAIRDWAVQNPNAAQGIEAVSNIFTAVIPVKGIGAVRGKYGLGGI
                     TAHPIKRSQMGAIALPKGKSAVSDNFADAAYAKYPSPYHSRNIRSNLEQRYGKENITS
                     STVPPSNGKNVKLANKRHPKTKVPFDGKGFPNFEKDVKYDTRINTAVPQVNPIDEPVF
                     NPKGSVGSAHSWSITARIQYAKLPRQGRIRYIPPKNYSPSAPLPKGPNNGYSAGNLSK
                     KVLTLVYINGKLKFGPSSLPSSALKAPVPIVGKAEAPPGKAVPVGEARIPSNPKAVKG
                     TTVTLSQEQRLANGELIPKGSVVTWSDNAVKVVRPDGKKRRFNSRDWEQKALPKPQLP
                     KDYRDDINIGGNNPRFNQQRHEKIESHNPNRIEEIRQRNAVSSAERQADALKRMQTSG
                     RTRLPGQPQKGKPGAAREMSSSDNPNQTAEAFARRYLGRKPTLMERVEGEKLYGGKCV
                     GCWKAQMPDGTFVVYRPAGNASMTKGTTASVDINNPTLNNLNINLKGKPTELKFKFPA
                     R"
     gene            21055..21516
                     /locus_tag="ACFOV4_000880"
     CDS             21055..21516
                     /locus_tag="ACFOV4_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618920.1"
                     /translation="MNLETAENIQCEFEYLALDGYFPMHFASHGQGNKDWQFAVEFIY
                     RLLICQLATLEPINFETKNDILDFCHNLAKQSPFNNDNEVWYQGEIVLTKKGIDLIKE
                     YIPEAFEEWNGKKFELNIPFIKTLKNIFVNYEVAWDENNPLFPIISLNLGT"
     gene            21503..21790
                     /locus_tag="ACFOV4_000881"
                     /pseudo
     CDS             21503..21790
                     /locus_tag="ACFOV4_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229180.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EndoU domain-containing protein"
     gene            21817..22236
                     /gene="mafI"
                     /locus_tag="ACFOV4_000882"
     CDS             21817..22236
                     /gene="mafI"
                     /locus_tag="ACFOV4_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MafI"
                     /protein_id="HFC7618921.1"
                     /translation="MYKIKCFYDQFSSGELFNYCQFLDNSSNQKINTRGTVYQYIIYV
                     LTGDLYLQKDIDENLEFIHQAENNPNEVYSGGGQGFCWDISAEKVVFYHNEFDEEDGW
                     PDLSCSLHTFKTALIAWNAFLQLPKSIHSVVETVIEE"
     gene            22326..22397
                     /locus_tag="ACFOV4_000883"
                     /pseudo
     CDS             22326..22397
                     /locus_tag="ACFOV4_000883"
                     /inference="COORDINATES: protein motif:HMM:NF026862.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin type 17 domain-containing
                     protein"
     gene            22394..22636
                     /gene="imm31"
                     /locus_tag="ACFOV4_000884"
     CDS             22394..22636
                     /gene="imm31"
                     /locus_tag="ACFOV4_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Imm31 family immunity protein"
                     /protein_id="HFC7618922.1"
                     /translation="MTNLKLDFYSEVIIKDSCPNDLLENGETIKGKKGVVLGISEEDG
                     IIYGYTILLFDIKYCIYIDKKYIIPTGKKFSRDDFY"
     gene            22714..22959
                     /locus_tag="ACFOV4_000885"
     CDS             22714..22959
                     /locus_tag="ACFOV4_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFC7618923.1"
                     /translation="MKDSTGQMRLATKDLAEAIKRGEVRSSAFTTKQLKAIEKGESKI
                     PDYTWHHHQDTGRMQLINEDLHHDTGHIGWRAMSKGK"
     gene            22962..23352
                     /locus_tag="ACFOV4_000886"
                     /pseudo
     CDS             22962..23352
                     /locus_tag="ACFOV4_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253928.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            23400..23570
                     /locus_tag="ACFOV4_000887"
                     /pseudo
     CDS             23400..23570
                     /locus_tag="ACFOV4_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706679.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            23573..23971
                     /locus_tag="ACFOV4_000888"
     CDS             23573..23971
                     /locus_tag="ACFOV4_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618924.1"
                     /translation="MLGLTRNNCDDLGFAILCYERNAADKKEFLDWLYGIVRTVPAES
                     FPRYLIDLIDCLESDDCSINIYNIIGFVPTTGMTKKEKDAVYGITYIRNQEFYDIPIT
                     REKALKALKKHPEIYQKFRHFFPFVELPPL"
     gene            24072..24461
                     /locus_tag="ACFOV4_000889"
     CDS             24072..24461
                     /locus_tag="ACFOV4_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618925.1"
                     /translation="MWKIIKEDSNDLGFAIKCLFSQSIDLNEFKLWIEQVIRDMPIED
                     IPFYIFDLADFDVGIGDIGNIVGFAPSSSLPKSKKNALTGIAFLRGIDVYDPPVSKEK
                     ALKALKKHPEIYQKFQHFFPFVELPPL"
     gene            24609..24998
                     /locus_tag="ACFOV4_000890"
     CDS             24609..24998
                     /locus_tag="ACFOV4_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618926.1"
                     /translation="MWKISKENCEDLGFAIVCMFYDAINLSEFKLWLDIVVRDTPIDT
                     IPLYIFDLIDFDKSIGEIYDVIGVVNYGYISNDQKNALTGIAFLRGIDVYDPPISKEK
                     ALKALEKYPEIYQRFQHFFPFVELPLF"
     gene            complement(25039..26496)
                     /locus_tag="ACFOV4_000891"
     CDS             complement(25039..26496)
                     /locus_tag="ACFOV4_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFC7618927.1"
                     /translation="MHKILPIAHVLSRLGMLFSFILLIPAALSYAFSDGAYTAFATTA
                     TVTLSGSYIVRLATLRFRRELRPRDGFTLVLMLWLAFAAMAAMPMYLYFPNMGFTDAF
                     FESMSGLTTTGATVIPHVDGLAPSVNFWRHMLNWLGGMGIIVLAVAILPMLGVGGTQL
                     FKAEIPGIDKESKMSPRISQVAKKLWFGYTLITILAAACLHFAGMGWFDAVCHAMATL
                     SLGGFSTHDASIAYYNSPLIEAVIIVFTIVGGINFANHFAALNSRSLKTYWKDEECRT
                     MLLLLSGSILAAALYLWHTGYYAGFTESLRYTAFNFVSIGLANGLANTDFAQWPLLIS
                     LWMFFLANILANSGSTGGGIKTIRALVLFKFSLREMMVLLHPKAVRTVKISGKAIPDR
                     LALTVMSFIFIYFMTVVLFSFLLMASGMEFTTAFTAVIACITNAGPGLGEVGPAGNYA
                     GLDVMQKWICVTAMLLGRLEIFTVFILFTPAYWKK"
     gene            complement(26511..27341)
                     /locus_tag="ACFOV4_000892"
     CDS             complement(26511..27341)
                     /locus_tag="ACFOV4_000892"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008803 -
                     bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="symmetrical bis(5'-nucleosyl)-tetraphosphatase"
                     /protein_id="HFC7618928.1"
                     /translation="MAHYAIGDIQGCFDELTSLLGKIGFNHGTDTLWLTGDIVNRGPK
                     SLETLQFCIRHENSVQIVLGNHDLHLLAVGCGEGAPKRSDTIEPILKHPDGKKMLDWL
                     RAQPLLIREGSRVMVHAGILPQWRIAKAESLAREAEAELRGKKYVKFFSKMYGNKPAA
                     WDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLD
                     RTIIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK
                     "
     gene            complement(27419..27808)
                     /locus_tag="ACFOV4_000893"
     CDS             complement(27419..27808)
                     /locus_tag="ACFOV4_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFC7618929.1"
                     /translation="MSKTIIHTDKAPAAIGAYSQAVRAGDTVYMSGQIPLDPATMTVV
                     GNGDFRAEARQVFQNLQAVAEAAGGTLADIVKLNAYLTDLGNFAVFNEVMAEFIAEPF
                     PARAAVGVASLPKGVQVEAEAVLVLNA"
     gene            complement(27944..28468)
                     /gene="nspA"
                     /locus_tag="ACFOV4_000894"
     CDS             complement(27944..28468)
                     /gene="nspA"
                     /locus_tag="ACFOV4_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein NspA"
                     /protein_id="HFC7618930.1"
                     /translation="MKKALAALIALALPAAALAEGASGFYVQADAAHAKASSSLGSAK
                     GFSPRISAGYRINDLRFAVDYTRYKNYKAPSTDFKLYSIGASAIYDFDTQSPVKPYLG
                     ARLSLNRASVDLGGSDSFSQTSTGLGVLAGVSYAVTPNVDLDAGYRYNYIGKVNTVKN
                     VRSGELSAGMRVKF"
     gene            complement(28575..>28901)
                     /locus_tag="ACFOV4_000895"
     CDS             complement(28575..>28901)
                     /locus_tag="ACFOV4_000895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618931.1"
                     /translation="AQTNRRPPGKTRPERVRKICLSMENAAASPAGRFRRHSRRRKCP
                     TLKAQTHTKNRMPAPATIRQIPLFFPNRLQVSPIRRVMPPPPFKGNARVNGFAVGKAA
                     GYRYVS"
BASE COUNT         6847 a         6597 c         8319 g         7138 t
ORIGIN      
        1 cgaagccgaa caatcgggca aactcaatat ctacaactgg tcggattatg tcgatcccga
       61 aaccgtcgcc gcctttgaaa aagaaaccgg catcaagacg cgttccgatt attacgacag
      121 caacgaaaca ctggaggcaa aagtcctgac cggcaaatcc ggctacgacc tgaccgcgcc
      181 gtccatcgcc aacgtcggcc ggcaaatcaa agcgggcgcg tatcagaaaa tcgacaaggc
      241 gcaaatcccc cattacggca acatcgataa agatttgctg aaaatgatgg aagccgtcga
      301 tccgggcaac gaatacgccg tcccctattt ctggggcatc aacaccttgg caatcaacac
      361 gcggcaggtg caaaaggcat tgggtacgga caagctgccc gaaaacgaat gggatttggt
      421 gttcaaccct gaatacaccg ccaaactcaa atcctgcggc atcagctatt tcgacagcgc
      481 aatcgaacag attcctttgg cgttgcacta tttgggcaaa gaccccaaca gtgaaaatcc
      541 cgaagacatc aaagccgccg tcgatatgat gaaagccgtc cgaggcgacg tgaaacgctt
      601 cagctcttcc ggctatatcg acgatatggc ggcgggcaac ctgtgtgccg ccatcggtta
      661 cggcggcgat ttgaacattg ccaaaacccg tgccgaagaa gccgcaaacg gcgtggaaat
      721 caaagtattg accccgaaaa ccggcgtggg cgtgtgggtg gattccttta tgattccgcg
      781 cgacgcgcaa aacgtcgcca acgcccaccg ctatatcgac tacacgctcc ggcccgaggt
      841 ggcggcgaaa aacggcagct tcgttaccta cgcgcccgcc agccgtcccg cgcgcgagct
      901 gatggatgaa aaatacacct ccgacgcatc gattttcccg aacaaagaac tgatggaaaa
      961 aagtttcatc gtatcgccca aatccgcaga atccgccaaa ctgggcgtga agctgtggca
     1021 agggctcaag gccggaaaat aaccgcaacc cctgccgtct gaaacctttc gggcggcagg
     1081 aaacggcgcg tccgttatca aacagggggg ggcgtttccc ctcctgccgg ttatgattgg
     1141 gttaagatta aaatgattta gtaaaatgag aaagatatga atttaagtat cgtagttccc
     1201 atttataatg tcgaaagtta tttggaagcg tgtttaagtt ccatagaacc tatattaagt
     1261 aatgaaaatg tcgaacttat ccttgtgaat gacgggtcaa aagacggaag tgaagatata
     1321 tgttataaat atatagataa aatatcaaac aacaaacaac aaacaacaaa caacaaacaa
     1381 caaacaacaa acaacaaaca acaaacaccg gacaccaaat atcaaatata tatatcagga
     1441 taaccaagga ttgtcagagg cgagaaatac cggaataaaa aattcaaacg gaaaatatat
     1501 agtctttatt gattcggatg attttattaa ttgtcaggtc ttgctggatt ttcttagtaa
     1561 agatgatatt gatatgccgg atgtggtttt tttaaatgca gttaaatatg ataagggaag
     1621 tgtttcatat tttggcgaag attatcagcc tgaaaaaata ctcaatcaat ccaaagtcga
     1681 agttttgaaa ggattatgcc gatttagaaa atttccgggt tcggcgtgga ataagattat
     1741 aaaaagagaa ttgattatta aagaaaaact gttttttgaa aagggaattt attctgaaga
     1801 tgtcgaatgg tcaatgagat tatttaatgc ggcaacaact ttttcttatt tggacggttg
     1861 ttattactat tatcggcagg gaagagaaga ttctattacg ggaactgttt cggaaaaaag
     1921 tataaagtca ttattatata ttttggagaa aaatgcggaa atggaattta atagggatat
     1981 atcaagttat ctttattctt ttctttccta cgaatatctc gttttgcttt ttatcatgac
     2041 gagtaaaaat atagcgtgtg atgctgatat aaaaagaagg gcgtatcatt taaggtttat
     2101 gctgttaaag tccaataaat tgatatataa gctgatattc ccgataatca cattattcgg
     2161 ggttgatatt acaggcagga ttttaaaagc aatcaggggg aatatttaat aaatccttta
     2221 acactataca tcttaccgaa ggaggaaaaa tgaacgcaat ccgaactttc caaaaccgca
     2281 cgcccgaaat ccacgaaagc tgtatgatag acgaagcgtg cgtcgtcatc ggcgaagtgt
     2341 cgcttgccga agacgtttcc gtgtggccgt gcgccgtgtt gcgcggcgat gtgaacagca
     2401 tcaccgtcgg cgcgcgcagc aatatacagg acggcagcgt cctgcacgtt tcccacaaaa
     2461 ccgccgccaa acccgaaggg tcgccgctgg ttatcggcga agacgttacc gtggggcaca
     2521 aagtgatgct gcacggctgc cgtatcggca accgcgtcct ggtcggcatg gggacgacgg
     2581 ttctggacga tgccgtgatt gaggacgaag tgatgattgg cgcgggcagc ctcgttccgc
     2641 cgcgtaaacg tttggagggt ggctatcttt atgtcggttc gccggtcaga caagtgcgcg
     2701 tgctgaccga tgaggaaaaa gcctttttga aatattccgc cgcgcattat gtgaagctgt
     2761 cgaaacagta cgggatgtga aatcacatcg gcgttcttgc gtcagcccca aattcatgcg
     2821 gacgggacgc atccgataac ggtatccgat gcgccttgat tttgaccgac tgcgtttggg
     2881 ttgcaggcaa aaatgccgtc tgaaagcctt ttttcgggtt cagacggcat tttattgccg
     2941 attgcttttt aaagtttgac cgaatgctcg cgcgtttcgt ggaacacgat gtccggccaa
     3001 cgttcttgcg tcagccctaa attcatgcgg acgggatgcc cgatagcggt atccgatgcg
     3061 ccttgatttt gaccgtctgc gtttgagttg caggcaaaaa tgccgtctga agcccttttt
     3121 tcgggtttag acggcatttt attgccgatt gctttttaaa gtttgaccga atgctcgcgc
     3181 gtttcgtgga acacgatgtc cggccagcgt tcttgcgtga gtcccagatt cacgcggttg
     3241 ggggcgaggt aggcgaggtt gccgcccgcg tcgatggcga ggttgcccgc gttggctttt
     3301 tcaaattccg ccagtttttt cttgtcgtcg cacgataccc agcgcgccga ccagatggat
     3361 gcgctgtcga acacggcttc cacgccgtat tcgttggcaa ggcgcgaggt aacgacttca
     3421 aactgcaaca cgccgaccgc gcccaaaatc aaatccgcgc cgctcattgg tttgaacacc
     3481 tgtaccgcgc cttcttcgcc gagttgttgc aagccttttt gcagttgctt gattttcagc
     3541 gggtttttga tgcggacgct gcggaacagt tcgggcgcga agaatgggat gccggtgaac
     3601 gccagttgtt cgccttcgga gaagctgtcg ccgatttgga tgttgccgtg gttcgggatg
     3661 ccgatgatgt cgccggcgta ggcttcttcc accagctcgc ggtcgtgcga catgaaggtt
     3721 accacgctgg aggcggcgat ttcgcggttg atgcgaaggt gtttcatctt cataccgcgc
     3781 tcgaatctgc cggagcagac gcgcaggaag gcgatgcggt cgcggtgttt cggatccata
     3841 ttggcttgga ttttaaagat aaatccggag aatttcggct cgtccggctc gaccatacgt
     3901 acggtcgcgt cgcgcggttt cggcgcgggc gtccagtcaa tcaatgaatt gaggatttcc
     3961 tgaataccga agttgttaat cgcagagccg aagaatacgg gcgtgagttc gccggcgagg
     4021 aattcgtcga gattaaactc gttggaagcc gcctgcacca attcgatttc gtcgcgcaac
     4081 tgctggattt ccaatggaaa gcgttgttcc aattcgggat tgtcgatgcc tttgatgatg
     4141 tcgaactcgt gcggcagacg ttcgccaccg gcttcaaaga gatagatttc gtcgttcagg
     4201 atgtggtaca cgcctttgaa gtttttgccc atgccgatcg gccaggttac gggcgcgcag
     4261 cggatttgca ggatgttttc cacttcgtcc agcaactcca aagaatcgcg cacttcgcgg
     4321 tcgtatttgt tcatgaacgt gacaatcggc gtattgcgca ggcggcagac gttcaagagt
     4381 ttgatggttt gcgcttccac accttttgcc gcgtcgatga ccatcaacgc gctgtccacg
     4441 gcggtcagaa cgcggtaggt gtcttcggag aagtcttggt gtcccggcgt gtccaagagg
     4501 ttgacggtgt ggtctttgta gtcgaactgc atcacgcttg atgccacgga aatgccgcgc
     4561 tgcttctcga tgtccatcca gtcggaggtg gcgaatttgc cggttttttt gccttttacc
     4621 gtacccgcgc tctgaatcgc gcccgaaaac agcaacagct tttcggtcag cgtggtttta
     4681 cccgcgtcgg ggtgggagat gatggcaaac gtgcggcggc ggcgcacttg gtcgaggatt
     4741 tcttgggaca tggttttctt tgcaaaaagg ttcaggccgc ttttcagacg gcccggacag
     4801 tgtttgagac ggcgaaattg tacaaaaaaa tgcctgataa ttcaatgttg gaggcggtca
     4861 gtgcgtgctg ccgtaaatct ctttttcgtc tttcaggacg gcatcggcgg tttcccacgc
     4921 gccgccgcgc cagactttgt aaaagcagct ttctcgcccg gtgtggcagg cgatgccgcc
     4981 gttttgggcg atgagcatca caatggcgtc gccgtcgcag tcgaggcgca gttcgcggac
     5041 tttttgcgtg tgtcccgact cttcgccctt catccattgt ttttggcgcg aacggctgta
     5101 atagtgggca aagccggttt cgacggtttt ttgcagggct tcggcgttca tccacgctac
     5161 cattaaaaca cgtttggttt cggcatcttg ggcgatggcg caaaccaaac ctttttcgtc
     5221 aaatttgacg gcttcaagca ggtttttatc catatttcct ttcagacggc atggtcgggg
     5281 cggtcagagg cgcacttcga tgccggcttc gcgcatagcg cgtttggctt cgcggatggc
     5341 gatttccccg aaatggaaaa cgccggcggc aagtacggca tcggctttgc cttcggttat
     5401 gccttcaatc aggtgccgga cattgccgac ccctccggag gcgatgacgg ggatgtcgac
     5461 ggcttcggca acggcgcggg tcagcggcag gttgaaaccc tgtttcgtac cgtccctgtc
     5521 catcccggtg agcaggattt cgcccgcgcc gcgtttttgc atttcgatcg cccattccac
     5581 cgcatccaaa ccggtcggat tgcgcccgcc gtgggtaaag atttcccagc gtgtgttttc
     5641 ggagttgacg gctttggcat cgacggcggc gacgatggct tgcgaaccga aaaatccggc
     5701 ggcttcgtca atcaggtcgg gacgggtaac ggcggcggtg ttgatgctga ctttgtccgc
     5761 gccggcattg agcaggcggc ggatgtcggc aacggtgcgt acgccgccgc cgacggtcag
     5821 ggggatgaag acttgtccgg caacctcttc gatgatgtgc aggatggtgt cgcggttgtc
     5881 ggatgaggcg gtgatgtcga ggaaggtcaa ttcgtccgcg ccttcgccgt tgtagcgttt
     5941 ggcggcttcg acggggtcgc ccgcgtcgcg caaaccgatg aagttcacgc ctttgacgac
     6001 gcgcccgtct tttacgtcga gacaggggat gatgcgtttt gccagtgcca taatcggatg
     6061 cctttagtcg agggaatctg ccagttgctg cgcttgggca aaatcgatgc tgccctcgta
     6121 aatcgcgcgg ccggtaatcg cgcctgctac gccatgtttt tcggcggcac acagggcgcg
     6181 gatgtcgtcc aagccggtca gtccgccgga ggcgatgacg ggaatgcgga cggcttgggc
     6241 gagtttgacc gtcgcgtcga tgttcacgcc gctcatcata ccgtcgcgcc cgatgtcggt
     6301 gtagatgatg ctgttgacgc cgtcgtcttc aaagcgtttt gccaaatcaa ttacatgatg
     6361 cccggttacg gttgcccagc cgtcgatggc ggccataccg tctttggcat ccagcccgac
     6421 aataatcctg ccggggaagg ctttgcacgc ctcgcgcacg aagtcggggt ttttgaccgc
     6481 cgccgtgccg ataatcacgt cgtttaagcc caaatccaaa tattgtccga tggttttcaa
     6541 atcgcgtatg ccgccgccga gctgtacggg gatgtctttg gcgacagcgg caaggatgtc
     6601 tttgatggcg ggcaggtttt gcggaacgcc ggcaaacgcg ccgttcaaat ctaccagatg
     6661 caggcggcgc gcgccttgtt tgaaccagtg cagcgcggtt tcggcgggcg aatcggaaaa
     6721 gacggtcgcc tcttccatca gcccttgttt caggcggacg cagcgtcctt ctttcaaatc
     6781 gatggcgggt atcagcagca taatttttct ccttgtgcgg ggccgtgtcc ggcttaccag
     6841 tttaaaaagt ttttcaacat cgtcagcccg gcatcgtggc ttttttcggt gtgaaattgc
     6901 gtggcgaata cgttgtcttt gccgacgatg caggcaaacg gggacgggta gtcgctttcg
     6961 cccaatatgg tttcgggatt ttcgggggcg aaatagtagc tgtggacgaa gtaaaaacgc
     7021 gtgtcttggg gaatatcttt aaacagcggg tggttttggg tttggcgcac ggtgttccag
     7081 cccatatgcg ggactttcag acggtatccc tgcgggtcgc ggaggtcgcg ctcaaagcgt
     7141 ctgactttgc cgccgaacca gcccaagccg tcggtgtttc cttcttcact gtggtcgaat
     7201 aaaagttgcg cgccgacgca gattccgaaa aagggtttgt tttttaaggc atctttgact
     7261 gcctcgtcca ggccgccgcg cgtcagtgcc gccatacagt cgggcatcgc gccctgcccg
     7321 ggaaaaatga ctttgtcggc gcgggacacg cgttcggggt cgccgcttaa aaagatttcg
     7381 gtattttttc cggcaagctg ccccgccgtc cggacggatt tcaatacgga atgcaggttg
     7441 cccataccgt aatcgataat ggcgatttgc atggcttcct cctctttttt tgcaatatgg
     7501 ctgcgatttt aacaaacaaa tgtgccgtgc tgataaaaat gccgtctgaa aacgggagtc
     7561 tgtcttcaga cggcataggg ttcaaacccg gaaagccgtt tgtcagcctt ccatttgttt
     7621 tgcctgaacg gcagtcaggg cgatggtgaa cacgatgtct tccaccagcg cgccgcgcga
     7681 caggtcgttg accggtttgc gcaggccttg cagcagcggg ccgacgctta agacgttggc
     7741 actgcgttgg acggctttat aggtgcagtt gccggtgttc aggtcgggga agaccaaaac
     7801 ggttgcctgt cctgccaccg ggctgcccgg ggctttggat ttgcccacgc ccggcacggt
     7861 tgccgcatca tattgcagcg ggccgtcgat ggcgaggtcg gggcgttttt cccgggcaag
     7921 tttggttgct tcgatgacgg tatcgacatc ggggccgctg ccggagttga cggtggagta
     7981 ggaaatcatc gccactttcg ggtcgatgcc gaaggctttt gcggaatcgg cagactggat
     8041 ggcgatgtcg gcaagctgtt gcgcggtcgg gttcggatta accgcgcagt cgccgaagac
     8101 gaggacttgg ttgggcagca gcataaagaa tacgctggac acgaggcttg cgcccggtgc
     8161 ggttttaatc agttgcaaag cggggcggat ggtgttggcg gtggtgtgaa ccgcaccgga
     8221 taccaaaccg tccacatcat tttgcgccat catcatcgta ccgagtacca cggtgtcttg
     8281 cagttgcttg cgcgcgtctt cgggtgtcag gcctttggat ttgcgcagtt cgcacatcgg
     8341 ctcgacgtat tgttcgacca atgaggcggg atcgatgatt tccaaagagt cgggcaggct
     8401 gatgccgcgt tctttggcaa cggcttcgac ttcttcgcgt ttggcaagca ggacgcagcg
     8461 ggcaatgcct ttttcgtggc agatggcggc ggcttggacg gtgcggggtt ctgcgccctc
     8521 aggcaggacg atgcgtttgt cggcttggcg ggcgaagtcg atcaggttgt agcggaattg
     8581 cgccggcgac aggcgttttg cttcgcggcc tgccaatacg gatacgtctt tcagcgcgtc
     8641 gctcgaaccg aagaaggtca ggccggtttt ttcggctgcc gcttcggcaa cggaggctgc
     8701 cgcgccgtcc acgacaaaac cttccaatac gcccggcgcg gcggcgaaga actgtttggc
     8761 aaggttcagc cgatttgcca gttcgtcggc atcggcgttg tcggaacgga cggcgaagac
     8821 ggctgccgcg tcaagggaca atgccagttc gacgtttttg cctgcgaggt agattttgtc
     8881 ggcatcgggc gcgatgcctt cgatgacgag gttggcggca tcgagtgcgg caactttgcc
     8941 gaccagtgcg tcgaaccagt cgtcgctttt gccttgcgcg agcagggttt cggcggttgc
     9001 gtcaacggct tggaaaattt gtgcgtccag tgcttttgca aaggcttgtg cggcggcgga
     9061 ggcgtccagt ccggcagata cgggtacgat gagtactttt gccatgatat atcctttcgt
     9121 atgctgcggt gtgcggcata tgtggttgga aggggcggca tataggcaga aacggctgcc
     9181 tgcgtgccgt gcgtgccgtg tttggcttga ggcgcgcagg ttgaatatag caaacaaatt
     9241 ctgtttccaa caagataaat atccgcaggc ttgtggatgc tgccgccttt cagagggtat
     9301 ttccggggaa gaacagggcg ggaccgtcca aatggaggac ggcggaaatg ccgtctgaca
     9361 gggtgggggc ggaagggagg ttgagcgtga ggacggtttg tccgacccgg agactgattt
     9421 cggtatgccg cgctttgggc gtggttttga gaaccacggc gtgaatggag gcggtgggtg
     9481 cggaatgggg gtgaaggctg aactgttccg gacggatgag cagtgtgccg cgtgtgcctg
     9541 cgggtgcgcc gctttgaacg ggcaggcggc ccaatccgca atcggcggtg ccgtcggcgt
     9601 tgagcgcggc ggggaacacg atgccttcgc cgataaacag ggcggcatca aggtcggcag
     9661 gttgtcggta caattcgtga gggcttgcag tttggaggat gcgcccctgt ttcatcacgg
     9721 caatccggtc ggcgtattgc agggcttctt cgcggtcgtg gctgacgaaa acggcagatt
     9781 tgccgttggc gcgcagggcg gcaatcatgt cttcgcgaat ctggcggcgc aactgttcgt
     9841 ccagcgcgct gaagggttcg tccaacaaaa tcagttcggg atcgggtgca agggcgcggg
     9901 cgagggcgac gcgctgttgc tgtccgcccg aaagttcgtg cggatagcgt ccggcaagtt
     9961 cggaaatgcc ggtcaattcc aacatagctt cgatgcgctg ccgttcttgc gccgtcttgc
    10021 ctttcccgtt gcccagcccg taggcggtgt tgcggtaaac ggtcaggtgg gggaacagca
    10081 caccttcctg tacgacataa cccaaacggc gttcgcggac ggggaggttg gtatttttcg
    10141 agaagatggt tctgccggaa agcgaaattt cgccaaaatc gggttgttca aaaccggcaa
    10201 ggcagcgtaa aagggtggtt ttgccgcagc cggacgcgcc gacgataaag aggatttcgc
    10261 ccgggtcgag gctgagcgaa atgtcgttta aaactggggt gttttgaaaa cttttggaca
    10321 ggtgtccgat gtgcagggcg gcggtcatgg cggtacttcc tcaagctgtt atttgaaggc
    10381 gtatttcttc agcaggaata cggggatgcc ggaaaataat accagcatca gcgcgtaagg
    10441 ggtggcggcg gcgtattgtg cgtccgatgt gtattcccaa acggcggtgg agagtgtgtg
    10501 gacatcgtcg gtggtcagca gcagggtggc ggtcagctct ttcatcagtt tgaggaagac
    10561 gagtgcgaat gcggcggtaa tgccgggcag gatggacggc agtaccaacg tcctgaaaat
    10621 aaagaagtgt ccgcgcccca atgttgcgcc gacctgttcc atccctttgg ggagttgttc
    10681 caaggaagtc ctcagggtgg tttgcgccat cggcaggtaa agcatgaaat aggcaaggat
    10741 gacgacgata aaggtttggt aaacggcagg ggtgtagttg atgctgaaat aaaccaagga
    10801 tagggcgata accaaaccgg ggacggcgtg cagtaaaaac ggcagcctgt ctatccaaac
    10861 ggttaaaaaa ttgcgatagc gaaccgatgc ccaaacaagg ggcaaggcac ataatatagt
    10921 caaaatcgca cctaaagccg atacgcttaa ggaacggata aaggcatcaa atacggatac
    10981 gagcgcgaat gtgccggaag tgccgaccat catccaatgt atcaatacgc caaaggggat
    11041 aataatgccc aaagtcaaca agctgcttaa aaaaacaatc gcgccgatct gaccgggcag
    11101 tttgagggtt ttgacgggat aaggacgggc aacgcctttg ccgctgtggt aaatcttggc
    11161 tttgtcgcga aatatgcttt ctccaaatac gacgatgccg cacaccgcca ttaaaacagc
    11221 ggaaagcagg gcggcggtat tgttgttgta ggacatttcg tattcttgga aaatggcggt
    11281 ggtaaaagtg gggtagttca aaatagatac cgcgccaaat tcgaccagca tatgcagggc
    11341 aatcagtaac acgctgctgc cgatggcggg tttgagctgg gggaggatgg cggaaaaaaa
    11401 ggtttgcagg cggcttttgc ccaaggacag gctgacttct tcgtaagaca ggctgatgcg
    11461 tttgagtgcc gcctcgacgg gcaggtaggc gagcgggaac gaggacaggc tcataatcat
    11521 cactgtcccc caaaagcctt cgacacggaa ggtcaggctg atccaggtga aacagctgac
    11581 aaatgcgggg atgcacaaag gcagggtgat tgccgtctga aaaaaggttt tgccgaagaa
    11641 gcggtaacgt tggaacaaaa gggcgcaggc aatgcccaaa acaatggaaa tcagggtaac
    11701 gcccgccatc atcgtcaagg tgttggagag caaatcccac atacgcgggc ggaacaacag
    11761 ttcgacggcg cggttgatgc cgacctgcca cgaacgcata gcgacatata aaaaaggcag
    11821 ggtaagcggt agggcaatca gtaggatgag gccggtaagc caaatgggta tttttttagg
    11881 agacatagtg tttttcatcg gcaaaacggg cggacagtat aaatgtccac ccgtttgaca
    11941 atccgaaaac ggcttatttc ataccggctt gctcaagcag ccgggtggcg tgttcttttt
    12001 cggaaacagt ggtggcggac acttggggtg cttccaactt ggcgatgggt tccaaattga
    12061 aagtggatac cacgtgcgga ttcaaaggat attcggcacg gacggcggtc agggcgcgct
    12121 gtccttcctt gctggcgagg aaggcgacga attttttcgc ctcatccttg ttttgggagg
    12181 attttaacac ggctgcgccg gaataggtaa cgagtgcgcc gggatctctg tggcggacga
    12241 aattcaggcg ggtgtggaca ttttgtacgc ctttttcacg cgcaaaagcg tgccagtagt
    12301 agttgttgat gagggcggca tcgatttcgc cgttttcaac cgcttgaagg gcgacggagt
    12361 ttttagcgta aggcttgccg tattctttca gacctttgag ccatttcaat gcggccgctt
    12421 cgcctttcag tttgacgatg gcgacaacct gttccaagaa cgcgccggaa gtgggggcgt
    12481 aaccgatgcg gtttttccat ttcggcgtgg cgtaattcag gacggatttt tccaaatctt
    12541 tttcagacag tttgcgggtg tcgtaaacga cgacgcgcga acgtccgctc agtgccaccc
    12601 agtctttttt ggcggcaacc ggcacgccct tgccgcgtgt ttcgttgatg gtggaggcgg
    12661 gcaggggctc taggaggttg gctgcggaaa gggtggcgag tgccgggatt tgttcggaat
    12721 agaatacgtc ggcggggctt cggctgcctt cttctttgat ttgaccggca agctggtcgc
    12781 ctttggcgct gttgagtttg actttgatgc cggtagcccg ggtaaaggca tctgcaacgg
    12841 cttgtgccgc ttctttgtgt tggccgttgt acacggtaat gtctgccagc gcgggggttg
    12901 cggcggtcag ggctgcggca agcagtgcgt atcggataga tgttttcata tcgattttct
    12961 cctaatgaat gagagtgtac accttgttaa gacataacgg cgtgtagtgt attccttctt
    13021 ctttataaat gcaaataatt attttttaaa tttgttatta tccgatccgg ttatggtttg
    13081 ttctgacttg tattttttcc gtgcatcgcg cccgtaaggc ggaagcggcg ggcaatgcgt
    13141 ggcggaatgt gggtaaaggc ggcattttga tttgtcggaa tgcttgagaa cccctctctt
    13201 taaaacagcg tctgaacagg gttgccggaa tagtattgcc atcccggcag atacagtttg
    13261 tcggggtctt gccaatattg ttcatccaga ctgttcggca gtgaggcggt tttgttgtcg
    13321 agatgttttg ttatatccca catttctttc aggtttttac cttccgattg gaggtggcgg
    13381 atttctttgt ccaatgcgtc tgccgcccga tggatcagca ttgcgctgtg tatcgcgccg
    13441 atttttttca gaacggaaca agtcttttcg gcggcgggga aactccagtt gcagacaaat
    13501 tgcagtatgc cgccgttgcc gatatcggct tctgcccgcc aaattaaaac cagctcctgt
    13561 tcccacccgt ccatgctttc gagtttgccg tcatgctgtt caaaaagttt gtccaccgcc
    13621 tgccacatca tctgttcgaa gcggtcggct tgggtatccg tatcggtcat agtgttcttg
    13681 tcttttaaaa atgccgtctg aacatttctt cagacggcat cgggggttaa gctgacattt
    13741 cccgccagcg tttgacttgg aaacggactt gttcaggcgc ggtaccgccc aagtggttgc
    13801 gcgcgtttaa gctgccttcg ggtgtcagca cgccgtaaac gtcgtcggca atcaaatcgc
    13861 tgaaaccttg taagacttcg agcggcagtt tgctcaaatc gacacccgct tggtcggcgt
    13921 ggcgcacggc ttgggcgacg acttcgtggg catcgcggaa aggcatgcct ttttttacca
    13981 agtaatctgc caaatcggtg gcggtagcga agccctgcat cacggcggcg cgcatattgt
    14041 cgggtttgac ggttacgccg cgcatcatat cggcgtaaat ccgcaacgtg tcgataagcg
    14101 tgtcggcggt gtcgaacaag ggttctttgt cttcctgatt gtctttgttg tacgccaagg
    14161 gctgcgattt catcagggta atcaagccga taaggtgtcc gatgactcgg ccggatttgc
    14221 cgcgcacgag ttcgggcacg tcgggatttt tcttctgcgg catgatggac gaacctgtgc
    14281 agaaacggtc ggcgatgtcg ataaagccga aacgcggact catccacaaa atcaattctt
    14341 cagacaggcg gctcaggtga accataacca gcgaggcggc agccgtgaac tcgacggcaa
    14401 aatcgcggtc ggatacggca tcgagcgagt tttggcagat ttgctcgaaa cccagtaatt
    14461 cggcggtaat ttcgcgccga atcgggtagg tcgtaccggc aagggcggct gcgccgagcg
    14521 gcatacggtt gacgcggcgg cggcagtccg ccatccgttc gttatcgcgg ccgagcattt
    14581 cgacgtaggc gagcatatgg tgtccgaagc tgacgggctg ggcgacttgc aggtgggtaa
    14641 agcctggcat gacggtttcg gcgttttgtt ccgccaaatc cagcaatgcc gtctgaaggc
    14701 tttgaatcag gcttcggatg acggtaatct ggtcgcgcag ccaaaggcgg atgtcggtgg
    14761 cgacttggtc gttgcggctg cggccggtgt gcaggcgttt gcccgcgtcg ccgattttgt
    14821 cggtcaggcg gcgttcgatg ttcatgtgga catcttccaa atcggacgac cattcgattt
    14881 tgccgctgcg gatttcttcg aggatttccg ccatgccccg acggatgtcc gccaaatcgc
    14941 cttcgtccaa cacgccggtt tctttcagca tttgcgcgtg ggcaagcgag ccttggatgt
    15001 cccattcggc aaggcgtcgg tcgaaaccga tggaggcggt gtattgtttg acgagttcgg
    15061 aaacgggttc gttgaaacgt ccggaccagg ttttgtcgtg cataaggatt ccttgatgtg
    15121 gttattcggt acggtatttt tccaaaaggc ggcggaaggg ttcgccggtt tcggggtgtt
    15181 tcaggccgta ggcgacggtg gcttccagat agcccagttt gctgccgcag tcgtagcgcg
    15241 tgccttcaaa ggggtgcgct aggacaaatt cgtgatcgag cagcttggcg atgccgtctg
    15301 taagctggat ttcgttgccc gcgccgcgcg gcagtccggt cagtaagtcg aaaatgcgcg
    15361 gggtgaggat gtagcgtcca acaacggcaa ggttggaggg cgcgtcttcg ggcttgggtt
    15421 tttcgacaat gccggtaatg cgttggaact gtttgagctg ttcggtttcg acgatgccgt
    15481 atgagccggt ttgcgatgct tcaacggttt ctacgcccaa aatgctgttg ccgctgcgcc
    15541 cgtacacttc gaccatttgt ttgagcgcgc ctttgggggc atcaatcagg tcgtcggcaa
    15601 ggataacggc aaagggttcg tctccgatgg cggcgcgggc gcacaagacg gcgtgtccca
    15661 agcccagtgc ttccgcctga cggatgtaga ggcaggtaat gttcggcggc aggatgttgc
    15721 ggacgtgttc caacaatttg tctttatggc gcatttccaa ctcggtttcg agttcgtatg
    15781 ccttgtcgaa atggtcttcg atgctgcgtt tgttgcgtcc ggtaacaaac accatttccg
    15841 tgcagccggc ttccacggct tcttctacgg cgtattggat cagcggcttg tcgacgatgg
    15901 gcagcatttc tttcgggctt gccttggtgg cgggcaggaa gcgtgttccc atccctgcga
    15961 cggggaagac ggcttttttt atcggtttca ttctttttcc tttgtattgt tttgatgttt
    16021 aaagggcgag tttgcggatt aaatcggcga gtgcctgctc gcggtggctt tcgcggtttt
    16081 tgacctccga atccaattcg gcggcggttt tgccgtgtcc gggcagataa aaatacgggt
    16141 cgtaaccgaa accgttttca ccggcgggaa cgccgttcca ttgtccgtgc catacgccct
    16201 cggcgataat tggacgcggg tcgtctttat ggcggacaaa aaccaatacg cagacgtagc
    16261 agcagctttt gtcggtcttg ccggcaagtt cggcggcaag tttcaggttg ttggcggtat
    16321 cggatttggg attgtcgccc gcgtaacgtg cggaatggat gcccggcgcg ccgtttaggg
    16381 cggcggcaca gatgccgctg tcgtcggcaa gcgcgggcag cccgctgtat tcggcggcat
    16441 ggcgtgcttt tgccagcgcg ttttcgacaa aggtgggata gggttcgggg cattcgggta
    16501 tgccgaatgc ggattgcggc aatacggtga tgctgtaagg tttgaataag ttgccgaatt
    16561 cttcgagctt gccggcattg ccgcttgcca aaacgatttt ttccggtttt tcagacatag
    16621 cggttttcct ttgcggcgga ttgggcggcg cgtagggatt tgtgccgcag gtagagggcg
    16681 aggctgccga tttgtccgaa cagtgcgccg aatgcgaaaa gaaaggaggc gacggcgaag
    16741 gctttgctgc cgacggtcag cagataagca cccaagagga cgagcagcat aaatgccagt
    16801 gtgaagaggg caacagacaa cagatagatt tttcggcggt tcatggcgtt cggtcggaaa
    16861 cggtatgttc ggattatagc cgattgggac ggtattccct agagcttgga aaaatgccgt
    16921 ctgaaacggc gttcagacgg catggcgggc gttatgcctg tttgttccaa cgttcgatgg
    16981 attctttgat gacttttttc gcttcttccg catcgcccca cgattcgact ttggtcgtac
    17041 ctgctttttt caggtctttg taatggttga agtggaactc gatttgtttg atcagctgtt
    17101 gcggcaaatc ggacaaagtt ttgtaggcgt tgccgttgtt gcggtcgtcg gcaggaacgc
    17161 agacgatttt gtcgtccact tcgccgtcgt caacgaattt catcacgccg ataacgcgcg
    17221 cttccaagaa tacgccggtt gccaaaggtt gttcggtaac gagcagcacg tccaattcgt
    17281 cgccgtcttc gtccaaagtt tggggaatga agccgtagtt ggtcggtttg gcgaagatgg
    17341 cgggttcgac gcggtcgagt tggaatgcgg ccagtttgcg gttccactcg attttgtggt
    17401 tgctgccggc ggggatttcg ttgacgacgt tgatgatgcc gccgtccaca tcgccggggg
    17461 tcaggatttg gttgaagtct gccatttggt ttcctttgtt tgggaaagtt tgaagtttga
    17521 aagtatagca caaacgtccg gctgaaaatg cgcccgatgc cgtctgaaag ggtgtacggg
    17581 cgcgtgttac cgtttgccca aaaacctgcc cagttccaga atcgcgcgcc tgttggacgg
    17641 ggaaaacact ttttccgccg cttcttccaa gccgaaccag ccgtaggaga cgtgttcttc
    17701 gggttgcagg gcgatgggcg tatcacgcgg gatttcggca gagaagaggt gttcgcggtt
    17761 ttcaaacacg ccttttggat agcggtgccg ccagtggtgg tagatttcgt aaaccgtgct
    17821 gtcgtgccag tcttgaagct gcccgtccgc cagcaggatg ccggtttctt cccaaacttc
    17881 gcgccttgcc gtttgggcga cggtttcgcc cggttcgagg ctgccggtta ccgactgcca
    17941 aaatccttcc ggatgcgtgc gttcgatgag caggatgccg ccgtccccgc tataaaggac
    18001 gaccagtgcg gagacggggt atttgagcgg ttttgccatc ggcatctttc ggcgggctgc
    18061 ggtaatgaag gggcggatta tagcaaacgc cgcacgttat ggcgtttatc cttttccgta
    18121 tccttttttc tgcacggatg ggacgcgccg gtgtttgccg gtaaattttc cgttgtgtca
    18181 aaaagataag ggcggttgtg attttaatgc ttgccaaagc gtcgggcgga aactataatc
    18241 cgaaacttat cgagtcggag tgtggcgcag tctggtagcg cacttgcatg gggtgcaagg
    18301 ggtcgaaggt tcgaatcctt tcactccgac caaaaattcc gaaagccgct ttcaaaagcg
    18361 gcttttttgc cgtccgtatg attatgatgt agagtacgcg gcgacagaca ttcaaatgcc
    18421 gtccgaaaac cgttcagatg gcatttcttt atcttaatag tggattaaca aaaatcagga
    18481 caaggcgacg aagccgcaga cagtacaaat agtacggaac cgattcactt ggtgcttcag
    18541 caccttagag aatcgttctc tttgagctaa ggcgaggcaa cgccgtactg gtttaaattt
    18601 aatccactat agtttcattc cgtaccatct taaggaacat caaattgggc atttcccgca
    18661 aaatatccct tattctgtcc atactggcag tgtgcctgcc gatgcatgca cacgcctcag
    18721 atttggcaaa cgattctttt atccggcagg ttctcgaccg tcagcatttc gaacccgacg
    18781 ggaaatacca cctattcggc agcagggggg aacttgccga gcgcagcggt catatcggat
    18841 tgggaaacat acaaagccat cagttgggca acctgatgat tcaacaggcg gccattaaag
    18901 gaaatatcgg ctacattgtc cgcttttccg atcacgggca cgaagtccat tcccccttcg
    18961 acaaccatgc ctcacattcc gattctgatg aagccggtag tcccgttgac ggattcagcc
    19021 tttaccgcat ccattgggac ggatacgaac accatcccgc cgacggctat gacgggccac
    19081 agggcggcgg ctatcccgct cccaaaggcg cgagggatat atacagctac gacataaaag
    19141 gcgttgccca aaatatccgc ctcaacctga ccgacaaccg cagcaccgga caacggcttg
    19201 ccgaccgttt ccacaatacc ggtagtatgc tgacgcaagg agtaggcgac ggattcaaac
    19261 gcgccacccg atacagcccc gagctggaca gatcgggcaa tgccgccgaa gctttcaacg
    19321 gcactgcaga tatcgtcaaa aacatcatcg gcgcggcagg agaaattgtc ggcgcaggcg
    19381 atgccgtgca gggtataagc gaaggctcaa acattgctgt tatgcacggc ttgggtctgc
    19441 tttccaccga aaacaagatg gcgcgcatca acgatttggc agatatggcg caactcaaag
    19501 actatgccgc agcagccatc cgcgattggg cagtccaaaa ccccaatgcc gcacaaggca
    19561 tagaagccgt cagcaatatc tttacggcag tcatccccgt caaagggatt ggagctgttc
    19621 ggggaaaata cggcttgggc ggcatcacgg cacatcctat caagcggtcg cagatgggcg
    19681 cgatcgcatt gccgaaaggg aaatccgccg tcagcgacaa ttttgccgat gcggcatacg
    19741 ccaaataccc gtccccttac cattcccgaa atatccgttc aaacttggag cagcgttacg
    19801 gcaaagaaaa catcacctcc tcaaccgtgc cgccgtcaaa cggaaagaat gtgaaactgg
    19861 caaacaaacg ccacccgaag accaaagtgc cgtttgacgg taaagggttt ccgaattttg
    19921 aaaaagacgt aaaatacgat acgagaatta ataccgctgt accacaagtg aatcctatag
    19981 atgaacccgt ctttaatcct aaaggttctg tcggatcggc tcattcttgg tctataactg
    20041 ccagaattca atacgcaaaa ttaccaaggc aaggtagaat cagatatatc ccacctaaaa
    20101 attactctcc ttcagcaccg ctaccaaaag gacctaataa tggatatagt gccgggaatt
    20161 taagcaaaaa agtcctgact ttagtttaca taaacggcaa actcaaattc gggccaagca
    20221 gtctgccgtc ttcggcattg aaagcacctg ttcccattgt cggcaaggct gaggctccgc
    20281 ccggaaaagc tgtgcctgtc ggcgaagccc gcattccttc aaatccaaaa gcggtaaaag
    20341 gaacaaccgt taccctgtcg caggaacaac gcctagccaa cggagagctg ataccgaaag
    20401 gctctgtggt aacgtggtcg gacaatgcgg tgaaggttgt gcggcctgat gggaaaaagc
    20461 ggagatttaa tagtcgggat tgggaacaga aggcattgcc gaaaccgcaa ctaccgaaag
    20521 attacagaga tgacatcaac ataggtggaa ataatcctag atttaatcag caacggcatg
    20581 aaaaaatcga atcccacaac ccaaacagaa tagaggagat acgccaacgt aatgccgttt
    20641 cttctgcaga aaggcaggct gatgcattaa aaaggatgca aacgtctggc cgcacccgcc
    20701 tgcctgggca gccacaaaaa ggaaaacccg gcgctgctag agaaatgtcc tcttcagaca
    20761 atccgaatca aacagccgag gcttttgcac gtcgatattt aggcaggaaa cctacactaa
    20821 tggaacgagt cgaaggtgaa aaattatacg gaggtaaatg tgtgggctgt tggaaagcgc
    20881 aaatgccgga cggaaccttt gtggtgtata ggccagcagg taatgcttct atgaccaagg
    20941 gaactactgc gtctgttgat attaataacc caacattaaa taacttaaat attaatttaa
    21001 aaggcaagcc aacagagtta aaatttaaat tccctgctag ataaggatgt tttaatgaat
    21061 ttagagacag cagaaaatat tcaatgcgaa tttgagtatt tagcattaga tggttatttt
    21121 ccaatgcatt ttgcatcgca tggtcaagga aacaaagatt ggcaatttgc agttgaattc
    21181 atatatagat tattaatatg tcaattagca actcttgaac ctatcaactt tgaaacgaaa
    21241 aatgatattt tagacttttg ccataattta gcaaaacaaa gtccttttaa taatgataat
    21301 gaggtgtggt atcaggggga aattgtatta acaaaaaaag ggatagattt aataaaggaa
    21361 tatattccag aggcgtttga agagtggaat ggaaagaaat ttgaattaaa cattcctttc
    21421 attaaaacat taaaaaatat atttgttaat tatgaggtag catgggatga gaataatcca
    21481 ctattcccca ttatatcttt aaacctcggc acctgataaa catggggttt atcaagcgac
    21541 agtggaaatt aaaaagcctg atggaagttg ggaaatgaaa aaaggaaggg gcggaaaacc
    21601 tatgacaaat cattctatgt tcccaaaaga ttgggatgag gctagaatta gggctgaagt
    21661 tacttcggct tgggagaaaa gaaaggaatt agaaggtcaa aaatggagag gtacaagtaa
    21721 atctggtgtt gaaatagaag gatttacgga acctaatcga acagcttatc cactttataa
    21781 tagtaaatga agtattgatt aaaaaggtgt ttttaaatgt ataaaataaa atgtttttat
    21841 gatcagttta gttctggtga attatttaac tactgccagt ttttagataa ttcttctaat
    21901 caaaagataa atacacgagg aacggtgtat caatatatta tttatgtttt aacaggagac
    21961 ctttatctac aaaaagacat agatgaaaat ttagaattta tccatcaagc agaaaataat
    22021 cccaatgaag tttattcagg aggtggacaa ggtttttgct gggatatttc tgctgaaaaa
    22081 gtagttttct atcacaacga atttgatgaa gaagacggct ggcctgattt aagctgttcg
    22141 ctgcatactt ttaaaactgc tttaattgct tggaatgctt ttttgcaatt gcctaaaagt
    22201 attcattcgg tggtggagac tgtgattgag gaataagcat aattagctta atgaatagaa
    22261 tcagcgatat agattggact gcaaatccac gcttatacgc tgtgccatga ttaacaggaa
    22321 gagagcaact tggatgggct agtagggatg gtaagcattt aaatatatca attgatggaa
    22381 agattacaca caaatgacta atttaaaatt agatttctac tctgaagtta ttataaaaga
    22441 ttcttgccct aatgatttgt tagaaaatgg tgagactatt aaaggaaaaa aaggagtggt
    22501 attaggtata agcgaagaag atggtataat ctatggctat actattttac tttttgatat
    22561 aaaatattgt atatatatag ataagaaata tattataccg actggaaaaa aattctctcg
    22621 cgatgatttt tattagctaa tttaagtaat ttaagcaagt tttttagata ctgaaactgg
    22681 taattatgtt tatgtaagca taaggagttc agattgaagg attctacagg gcaaatgagg
    22741 ctggcaacca aggatttggc ggaagccatt aaacgaggag aagtacgtag ttctgctttt
    22801 acaacaaagc aactaaaggc aatcgaaaaa ggagaatcta aaataccgga ttacacttgg
    22861 catcatcatc aagacactgg aaggatgcaa ttgattaatg aagacttgca tcatgatacc
    22921 ggccatatcg gttggagagc gatgagtaaa ggaaagtaac tatgtggaaa atcataaaag
    22981 aggatagtga tgatttagga tttgcaatta aatgcttatt ctctcaatct attgatttaa
    23041 atgaattcaa attatggatt gaacaagtaa tacgagatat gcccatcgag gacatccctt
    23101 tttatatttt tgacttggcg gatttcgatg gggtaattgc cgatattgac aatattgtag
    23161 gttttgtttc gagttacagc ctatcaaaat cgaaaaaaaa atgccttgac cggcattgcc
    23221 ttcttaaggg ggatagatgt ctatgaccct cccgtttcaa aagaaaaagc attaaaagcc
    23281 ttagagaaat atcctgaaat ttatcagaaa tttcagcatt tctttccgtt tgtagagctg
    23341 cctccgcttt aaacagtcaa aatgccgtct gaaacaatat tcggctttca gacggcattt
    23401 ttgatacaaa gcaggtaacc aaaagagtgt ttgacggaaa aggagaagct aaaataccga
    23461 gctatacttg gcatcatcat caggatacgg gacgaatgca gttaatatcc gaaagaaagc
    23521 atacgcaaac agggcatata ggtggtgaag caatggataa aggaaaatga ttatgttggg
    23581 gcttacacgg aacaattgtg atgatttggg atttgctata ttgtgttatg agcgcaatgc
    23641 agccgacaaa aaagaattct tggattggtt atatggaatt gtcaggactg tccctgccga
    23701 aagttttcca aggtatctga ttgatttaat agattgtttg gaatcagatg attgttccat
    23761 aaatatatat aatattattg gctttgttcc aactaccggt atgacgaaaa aggaaaaaga
    23821 tgccgtatat ggcattacct atatacggaa tcaagagttt tacgatattc cgattactag
    23881 ggagaaggcg ttaaaagcct taaaaaaaca tcctgaaatt tatcagaagt ttcggcattt
    23941 ctttccgttt gtagaactgc ccccgcttta aacagtcaaa atgccgtctg aaacgatatt
    24001 cggctttcag acggtatttt tgatataaag cgggtaacta aaagagcgtt tgacggcaaa
    24061 ggaagataat tatgtggaaa attataaaag aggatagtaa tgatttagga ttcgcaatta
    24121 aatgcttatt ctctcaatct attgatttaa atgaattcaa gttatggatt gaacaagtaa
    24181 tacgagatat gcccattgag gacatccctt tttatatttt tgatttggcg gatttcgatg
    24241 taggaattgg cgatattggc aatattgtag gttttgctcc gagttccagc ctgccgaaat
    24301 cgaaaaaaaa tgccttgacc ggcattgcct tcttaagggg gatagatgtc tatgaccctc
    24361 ccgtttcaaa agaaaaagca ttaaaagcct taaagaaaca tcctgaaatt tatcagaaat
    24421 ttcagcattt ctttccgttt gtagagctgc ctccgcttta aacagtcaaa atgccgtctg
    24481 aaagaccgtc cgccgttcag acggcatttt tgatataaag cggataacta aaagagcgtt
    24541 tgacggcaaa ggagaatcta aaataccgga tgtatcggtt gggaagcaat ggataaaggt
    24601 aaataattat gtggaaaatt agtaaagaaa attgtgaaga tttaggattt gcaatagtct
    24661 gtatgttcta tgatgctatt aatctttctg aatttaaatt atggttggat atagttgtca
    24721 gagatactcc tattgataca attccattgt atatttttga tttgattgat tttgataaga
    24781 gtatagggga aatttatgat gtaattggag tcgttaatta tggttacatt tcaaatgatc
    24841 aaaaaaatgc attaacgggc attgccttct taagggggat agatgtctat gatccgccta
    24901 tttcaaaaga aaaagcatta aaagccttag agaaatatcc tgaaatttat cagaggtttc
    24961 agcatttctt tccttttgta gagcttccgc ttttttaaaa gacaatatgc cgtctgaaaa
    25021 gttttcagac ggcatttttt atttcttcca gtaggcgggg gtgaagagga tgaagacggt
    25081 gaagatttcc agcctgccca agagcatggc ggtaacgcag atccatttct gcatcacgtc
    25141 caaaccggcg taattgccgg cgggcccgac ttcgcccagg ccggggccgg cgttggtgat
    25201 gcaggcgatg acggcggtga aggcggtggt aaattccata ccgctcgcca tcagcaggaa
    25261 gctgaagagg acgacggtca taaagtagat gaagatgaag gacataacgg tcagcgcgag
    25321 gcggtcgggt atggccttgc cgctgatttt gacggtgcgg acggctttgg ggtgcagcag
    25381 caccatcatt tcgcgcaggc tgaatttgaa caggacgagg gcgcgtatgg ttttgatgcc
    25441 gccgccggtc gagccggagt tggcgaggat gttggcgagg aaaaacatcc acagggaaat
    25501 caggagcggc cattgtgcga agtcggtgtt ggccagcccg tttgccagtc cgatggagac
    25561 gaagttgaag gcggtgtagc gcagggattc ggtaaaaccg gcgtaatagc cggtgtgcca
    25621 caggtacagg gcggcggcaa ggatgctgcc ggagagcagc agcagcatcg tccggcattc
    25681 ttcgtctttc caataggttt tgaggctgcg gctgttgagg gcggcgaaat ggttggcaaa
    25741 attgatgccg ccgacaatgg tgaaaacgat gatgaccgct tcgatgaggg gggagttgta
    25801 ataagctatg ctggcatcgt gggtggaaaa cccgcccagc gagagggtcg ccatcgcgtg
    25861 acagacggca tcgaaccagc ccatcccggc aaaatgcagg caggctgccg cgaggatggt
    25921 gatcagggtg tagccgaacc agagtttttt cgccacttgg gaaatgcgcg gcgacatttt
    25981 gctttctttg tcaatgccgg ggatttcggc tttgaataat tgcgtgccgc ctacgccgag
    26041 cataggcagg atggcgacgg caaggacgat gatgcccatc ccgcccagcc agttgagcat
    26101 atgccgccaa aagttgacgg agggggcgag cccgtcgacg tgggggatga cggtcgcgcc
    26161 ggtggtggtc agtcccgaca tcgattcaaa aaatgcgtcg gtaaagccca tattcgggaa
    26221 atacaggtac atcggcatcg cagccatagc ggcaaacgcc agccacaaca tcaggacgag
    26281 ggtgaagccg tcgcgcgggc gcagttcgcg cctgaaccgg agggtggcga gccggacgat
    26341 gtacgagccg gaaagggtaa cggtcgcggt ggtggcgaag gcggtgtacg cgccgtccga
    26401 aaaggcgtag gagagggcgg cgggtatcag caggataaag gaaaacagca tacccagtcg
    26461 ggagaggacg tgggcgatgg gcaggatttt gtgcatagtg gggcggtccg ttattttgcg
    26521 aagcttttcc agtctatgcc gccggcggct tggacttggg taatttcttc cgtttcgagg
    26581 ttgacggcgg tcagctgtcc gccccacagc gcgccggtgt ccagcgagat gacgttgtcg
    26641 gcattcgtgt agcccagcga ggaccagtgt ccgaagatga tggtgcggtc gaggttttgc
    26701 cggtcggggg ctttgaacca cgggcgcagg taaggcggca tttttttcac tgtggatttg
    26761 tagtcgaaat ccagttcgtt tttaaaggtc agggcgcgca tccgcgtgaa ggcgttgacg
    26821 atgaagcgca ggcgggcata gccttccaaa ccttcgtccc acgcggccgg tttgttgccg
    26881 tacattttgg agaagaattt gacgtatttt ttgccgcgca gttcggcttc ggcttctcta
    26941 gcgagcgatt cggctttggc gatgcgccat tgcggcagga tgccggcgtg taccatcacg
    27001 cggctgccct cgcgtatcaa cagcggttgc gcacgcagcc agtcgagcat tttttttccg
    27061 tcggggtgtt tgagtatggg ttcgattgtg tcgctgcgtt tgggcgcgcc ttcgccgcag
    27121 ccgacagcga gcaggtgcag gtcgtggttg ccgaggacga tttgcacgct gttttcgtgc
    27181 cggatgcaga attgcagcgt ttcgagggat ttcgggccgc ggttgacgat atcacccgtc
    27241 agccagaggg tgtccgtgcc gtggttgaag ccgattttgc cgagcagtga ggtcagttcg
    27301 tcgaaacagc cttgtatgtc gccgattgcg taatgtgcca ttgcagatgt tgtgaagtgg
    27361 gaaagtgttg cggttcggac ggcatggttt tgaaatatca tgcagtccga acgtggaatt
    27421 atgcgttcaa aacgaggacg gcttcggctt cgacctgcac gcctttgggc agcgaggcaa
    27481 cgccgacggc ggcgcgggcg gggaagggct cggcgataaa ttccgccatg acttcgttga
    27541 agacggcaaa attgcccaag tcggtcaggt aggcgttgag tttgacgatg tcggccagcg
    27601 tgccgcctgc cgcttcggcg acggcttgca ggttttggaa cacttggcgc gcttcggcgc
    27661 ggaaatcgcc gttgccgacg acggtcatcg tggcgggatc gagggggatt tgaccgctca
    27721 tgtaaacggt gtcgcctgct cggacggctt ggctgtacgc gccgatggcg gcgggggctt
    27781 tgtcggtgtg gatgatggtt ttggacattt cggattcctc aaaaaatagg gcggcagaag
    27841 ccgcagcatt cgggattatc gtacaaaacc gccggcttgt gtagttgcgg tggcagaaaa
    27901 caaaaccgcc gaaggctcgg cggtttgcag aataaggcgc atatcagaat ttgacgcgca
    27961 taccggcgga cagttcgccg gaacggacgt ttttgacagt gttgactttg ccgatgtagt
    28021 tgtagcggta gccggcatcc aaatcgacat tcggggtaac ggcatagctt acgcccgcca
    28081 atacgccgag gccggtggag gtttggctga agctgtcgct gccgcccaag tcgacggagg
    28141 cgcggttgag gctcaagcgc gcgccgagat acggtttgac gggcgattgg gtgtcgaagt
    28201 cgtaaatggc ggacgcgccg atgctgtaaa gtttgaaatc ggtggatggg gctttatagt
    28261 ttttgtagcg cgtgtaatcg acggcgaagc ggaggtcgtt gatgcggtag cctgcggaga
    28321 tgcgcgggct gaagcctttg gcagaaccta aagagcttga ggcttttgcg tgtgcggcat
    28381 cggcttggac gtaaaagccg gatgcgcctt ccgccagtgc ggcggccggg agagcgaggg
    28441 caatcagtgc ggcaagtgct tttttcatat tttggttcct ttatggtcag ttagaaaaat
    28501 tgttaagaat ccgttaaaga atcctgctgt attatactta aattttcttt ttgcatcgta
    28561 atattttcaa tacttcaaga tacgtagcgg tatccggctg ctttgccgac ggcaaagccg
    28621 ttaacccgcg cgttgccttt aaatggtggc ggcggcatca cgcggcggat gggtgaaact
    28681 tgcaaacggt ttggaaaaaa cagcggtatc tgtcggattg ttgcaggtgc aggcatacgg
    28741 ttttttgtgt gcgtctgtgc cttaagcgtc ggacatttcc ggcggcggct gtgccgtctg
    28801 aaacgcccgg cgggggatgc ggctgcgttt tccatcgata agcatatttt ccggacgcgt
    28861 tcggggcggg ttttcccggg cggccgccga tttgtttgcg c
//
LOCUS       DAXISH010000020        27922 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.020, whole genome shotgun sequence.
ACCESSION   DAXISH010000020 DAXISH010000000
VERSION     DAXISH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 27922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27922
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.020"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(63..1991)
                     /gene="dnaK"
                     /locus_tag="ACFOV4_000896"
     CDS             complement(63..1991)
                     /gene="dnaK"
                     /locus_tag="ACFOV4_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFC7618932.1"
                     /translation="MAKVIGIDLGTTNSCLAISENGQTKVIENAEGARTTPSVIAYLD
                     GGEILVGAPAKRQAVTNAKNTIYAAKRLIGHKFEDKEVQRDIESMPFEIIKANNGDAW
                     VKAQGKELSPPQISAEVLRKMKEAAEAYLGEKVTEAVITVPAYFNDSQRQATKDAGRI
                     AGLDVKRIINEPTAAALAFGMDKGDNKDRKVAVYDLGGGTFDISIIEIANLDGDKQFE
                     VLATNGDTFLGGEDFDQRLIDYIIDEFKKEQGIDLKQDVMALQRLKEAAEKAKIELSS
                     GQQTEINLPYITMDATGPKHLAMKITRAKFESLVEDLIARSIEPCRTALKDAGLSTGD
                     IDDVILVGGQSRMPKVQEAVKDFFGKEPRKDVNPDEAVAVGAAIQGEVLSGGRSDVLL
                     LDVTPLSLGIETMGGVMTKLIQKNTTIPTKASQVFSTAEDNQSAVTIHVLQGERERAS
                     ANKSLGQFNLGDIAPAPRGMPQIEVTFDIDANGILHVSAKDKGTGKAANITIQGSSGL
                     SEEEIERMVKDAEANAEEDKKLTELVASRNQAEALIHSVKKSLADYGDKLDAAEKEKI
                     EAALKEAEEAVKGDDKAAIDAKTEALGAASQKLGEMVYAQAQAEAQAGESEQANASAK
                     KDDDVVDADFEEVKDDKK"
     gene            complement(2199..2471)
                     /locus_tag="ACFOV4_000897"
     CDS             complement(2199..2471)
                     /locus_tag="ACFOV4_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618933.1"
                     /translation="MKKTGKYLIYTAAFTAFCFAFQENRSEAKQPDITLSASLCEQFN
                     ILNAKDMDAEQVSLSKECDIIESSHDWEKEYGNLNEQEMLAGIVYE"
     gene            2659..3345
                     /locus_tag="ACFOV4_000898"
     CDS             2659..3345
                     /locus_tag="ACFOV4_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC7618934.1"
                     /translation="METFKDRLVFLWKSEARQAKIASDIEMTIAGFSRIWNEGGLPKS
                     ETLKKIKQLKGCSIDWLLTGEGNPFPDEAPKKSLAYDTLGNEVDTDEFVFVPRYDIRA
                     AAGYGQFVDHEEPVFTMAFRRHWIENYVTRDTKNLSVISVKGDSMEGVLNDGDSILVN
                     HGENTPRDGLYVLRINENLLVKRLQIVPGGIINVISANEAYPAFEINLNDLTDDVEII
                     GRVEWFGRTI"
     gene            3477..3815
                     /gene="erpA"
                     /locus_tag="ACFOV4_000899"
     CDS             3477..3815
                     /gene="erpA"
                     /locus_tag="ACFOV4_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HFC7618935.1"
                     /translation="MSDESPIIFTDSCCAKVADLIAEENNPDLKLRVFVNGGGCSGFQ
                     YGFTFDEIKNDDDFEIEKNGLVFLVDPMSYQYLVGAEIDYTESLQGSQFVIRNPNAET
                     TCGCGSSFSV"
     gene            3832..3978
                     /locus_tag="ACFOV4_000900"
     CDS             3832..3978
                     /locus_tag="ACFOV4_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618936.1"
                     /translation="MPSERSDGIFTFRKYIIGMNSHIIRLFEDESGFPKGTGGTVSGV
                     FVPL"
     gene            3975..4439
                     /locus_tag="ACFOV4_000901"
     CDS             3975..4439
                     /locus_tag="ACFOV4_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFC7618937.1"
                     /translation="MIEMSKDYRNDLYDVYVSYPPQVDRGLIRECLKENLGEEKAEGL
                     IESLDSKPQVLVEEKCTWAKREELHDYFSYLGLDIITRRYMELETVVPPEEGEGEGEG
                     ADGEMPEYLELHGGREDDISAPSQPEPPSRNIKLLVFGLLIAFLGYLLGKIF"
     gene            4474..5985
                     /gene="ubiB"
                     /locus_tag="ACFOV4_000902"
     CDS             4474..5985
                     /gene="ubiB"
                     /locus_tag="ACFOV4_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HFC7618938.1"
                     /translation="MKWLKRLTVIVGTFYRYRLAGLCASLMGSGWICALLKMMPQSSK
                     LKNEPPAVRLRLALESLGPIFIKFGQVLSTRPDLIPHDYAVELAKLQDKVPPFDARLS
                     REQIEKSLGQSIEKLYAEFETEPIASASIAQVHKARLHSGERVAVKVLRPNLLPLIEQ
                     DLSLMRFGAAWVERLFSDGRRLKPLEVVAEFDKYLHDELDLMREAANAGQLGRNFQNS
                     NMLIVPKVFYDYCTSDVLTIEWMDGTPVADIAKLKADGIDLHKLADYGVEIFFTQVFR
                     DGFFHADMHPGNILVAADNRYIALDFGIVGTLTDYDKRYLAINFLAFFNRDYRRVATA
                     HIESGWVPADTRAEELEAAVRAVCEPVFNKPISQISFGLVLMRLFEVSRRFNVEIQPQ
                     LVLLQKTLLNIEGLGRQLDPDLDLWKTAKPFLVKWMNGQVGPKALWRNLKNEAPDWAQ
                     IIPSLPRKISALIDENRQQEMRDAYIHLVKVQQRQSLWLAVIAVVLLLILLLK"
     gene            complement(6342..7160)
                     /gene="cysE"
                     /locus_tag="ACFOV4_000903"
     CDS             complement(6342..7160)
                     /gene="cysE"
                     /locus_tag="ACFOV4_000903"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFC7618939.1"
                     /translation="MKKDHLNTTGFDLWHTIREETAAAVSAEPMLASFLHQTVLRHES
                     LGSVLAYHLSSKLGSPIMDVRALFEIYQQALGSDTQIGKCVEADLKAIYERDPACDEY
                     SLPLLYFKGFHAIQAHRINHRLYLDGRKTLAYFLQNRMSEVFGVDIHPAARFGYGLML
                     DHATGFVAGETAVLGNNISILHGVTLGGSGKEGGDRHPKIGDGVMIGANASILGNIRI
                     GSNAKIGAGSVVVSDVPPSITVVGVPAKPVARSLKTPSADMDQNIQFTEIDFMI"
     gene            7344..7922
                     /gene="grpE"
                     /locus_tag="ACFOV4_000904"
     CDS             7344..7922
                     /gene="grpE"
                     /locus_tag="ACFOV4_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFC7618940.1"
                     /translation="MSEQTQQQNSEEAVENVEAVETVETVGNADGVQEQAAAEPAYED
                     LQARIAELEAQLKDEQLRALANEQNLRRRHQQEIADTHKFAGQKFAVEMLPVKDYLEM
                     ALLDQSGNFDALKMGVQMTLNELQKAFDATQIKEINPKAGDKLDPNIHQAMQAVASEQ
                     EPNTVVGVMKKGYTLSDRVLRPAMVTVAQKEA"
     gene            complement(8199..8414)
                     /gene="nqrM"
                     /locus_tag="ACFOV4_000905"
     CDS             complement(8199..8414)
                     /gene="nqrM"
                     /locus_tag="ACFOV4_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Na+)-NQR maturation NqrM"
                     /protein_id="HFC7618941.1"
                     /translation="MKTLLLTFGIFLTVIIGMAVGYIFSKRSIKGSCGGITALGMKKM
                     CDCDTPCDTLQKKLDEEKQAGGIRVDR"
     gene            complement(8440..9495)
                     /locus_tag="ACFOV4_000906"
     CDS             complement(8440..9495)
                     /locus_tag="ACFOV4_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFC7618942.1"
                     /translation="MPSETRLPNFIRVLIFALGFIFLNACSEQTAQTVTLQGETMGTT
                     YTVKYLSNNRDKLPSPAEIQKRIDDALKEVNRQMSTYQPDSEISRFNQHTAGKPLRIS
                     SDFAHVTAEAVRLNRLTHGALDVTVGPLVNLWGFGPDKSVTREPSPEQIKQAASYTGI
                     DKIILKQGKDYASLSKTHPKAYLDLSSIAKGFGVDKVAGELEKYGIQNYLVEIGGELH
                     GKGKNARGEPWRIGIEQPNIVQGGNTQIIVPLNNRSLATSGDYRIFHVDKNGKRLSHI
                     INPNNKRPISHNLASISVVADSAMTADGLSTGLFVLGETEALKLAEREKLAVFLIVRD
                     KGGYRTAMSSEFEKLLR"
     gene            complement(9648..10865)
                     /gene="nqrF"
                     /locus_tag="ACFOV4_000907"
     CDS             complement(9648..10865)
                     /gene="nqrF"
                     /locus_tag="ACFOV4_000907"
                     /EC_number="7.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit F"
                     /protein_id="HFC7618943.1"
                     /translation="MEIILGIVMFTVIVLVLALMILFAKSKLVSEGDITIKVNGEKEL
                     TMPAGGKLLGALANEGIFIPSACGGGGSCGQCRVVVKSGGGDILPTELSHISKREARE
                     GCRLSCQVSVKTDMDIEVPEEVFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFR
                     AGGYIQIEAPPHTVAYKDFDIPKEYHEDWDKYNLWQYVSKVDEPILRAYSMASYPEEK
                     GIIMLNVRIATPPPRVPDAPPGQMSSYIWSLKPGDKVTISGPFGEFFAKDTDAEMVFI
                     GGGAGMAPMRSHIFDQLKRLNSKRKITFWYGARSKREMFYVEDFDQLAAEFPNFTWHV
                     ALSDPLPEDNWDGYTGFIHNVVYENHLKNHEAPEDCEFYMCGPPIMNQSVIKMLKDLG
                     VEDENILLDDFGG"
     gene            complement(10879..11472)
                     /gene="nqrE"
                     /locus_tag="ACFOV4_000908"
     CDS             complement(10879..11472)
                     /gene="nqrE"
                     /locus_tag="ACFOV4_000908"
                     /EC_number="7.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit E"
                     /protein_id="HFC7618944.1"
                     /translation="MEHYLSLFIKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGVA
                     VIFVLGLSVPVNQLVYSLLKDGAIVEGVDLTFLKFITFIGVIAALVQILEMFLDKFVP
                     ALYNALGIYLPLITVNCAIFGAVSFMAQREYNFGESVVYGFGAGLGWMLAIVALAGIT
                     EKMKYSDAPKGLKGLGITFIAAGLMAMAFMSFSGIQL"
     gene            complement(11476..12102)
                     /locus_tag="ACFOV4_000909"
     CDS             complement(11476..12102)
                     /locus_tag="ACFOV4_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit D"
                     /protein_id="HFC7618945.1"
                     /translation="MADMKRLKHLMFSPFIDNNPIALQVLGICSALAVTTKLQTAIVM
                     GISVALVTGFSSFFISLVRNYIPNSIRIIVQMAIIASLVTLVDQLLQAFAYELSKQLS
                     VFVGLIITNCIVMGRAEAFAMKEPPLESLIDGIGNGAGYGMMLLVVATVRELIGSGKL
                     LGYTVFQTVQDGGWYQTNGLFLLAPSAFFIIGFLIWGLRTWKPEQAEE"
     gene            complement(12102..12878)
                     /locus_tag="ACFOV4_000910"
     CDS             complement(12102..12878)
                     /locus_tag="ACFOV4_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit C"
                     /protein_id="HFC7618946.1"
                     /translation="MAKKFDKDSFSGTLIVVLAVSLICSVIVAGAVVGLKPIQEKQKL
                     QDKQGYILSVAGLMDKDTDIGKTFAERIEQRVVDLATGEYVADAPKDFSARIAGKDPA
                     QSIRIKPEDDLAGIKSRAKYTEVYLVKGEDGKIGQIILPMHGNGLWSVMYGFVAIQPD
                     GNTINGITYYEQGETPGLGGEIGNPLWQQKFVGKKLFDGQGKLALHVGKGAGSDKEHG
                     VDALSGASLTSKGVQGSFAYWFGENGYIPYLNKLKSAGAQ"
     gene            complement(12871..14103)
                     /locus_tag="ACFOV4_000911"
     CDS             complement(12871..14103)
                     /locus_tag="ACFOV4_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit B"
                     /protein_id="HFC7618947.1"
                     /translation="MGLKHFLEKIEPHFLPGGKHEKWYALYEAAATIFYTSGAVTRKA
                     AHVRDALDSKRMMILVWLALFPAMFYGMYNVGVQAFGALTPDLLQQNIANDWHYTLAD
                     ALGINMSSEASVLGKMLFGAIYFLPIYATVFAVGGFWEVLFATVRKHEINEGFFVTSI
                     LFALIVPPTLPLWQAALGISFGVVVAKEVFGGTGKNFMNPALAGRAFLFFAYPANLSG
                     DAVWTAVDGYSGATALAQWAAHGADGLKNAVTGQTITWMDAFIGKLPGSIGEVSTLAL
                     LIGGAFIVFARIASWRIIAGVMIGMIAMSSLFNFIGSDTNAMFAMPWYWHLVVGGFAI
                     GMLFMATDPVSASFTNVGKWWYGALIGVMCVLIRVVNPAYPEGMMLAILFANLFAPIF
                     DYFVAQANIKRRKARSNG"
     gene            complement(14106..15449)
                     /locus_tag="ACFOV4_000912"
     CDS             complement(14106..15449)
                     /locus_tag="ACFOV4_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit A"
                     /protein_id="HFC7618948.1"
                     /translation="MIKIKKGLNLPIAGRPEQVIYDGPAITEVALLGEEYAGMRPSMK
                     VKEGDAVKKGQVLFEDKKNPGVVFTAPASGKIAAIHRGEKRVLQSVVIAVEGNDEIEF
                     ERYAPEALANLSGEEVRRNLIQSGLWTALRTRPFSKIPAVDAAPFAIFVNAMDTNPLA
                     ADPVVVIKEAAEDFRRGLLVLSRLTERKIHVCKAAGADVPSENAANIETHEFGGPHPA
                     GLSGTHIHFIEPVGANKTVWTINYQDVIAIGRLFATGRLNTERVVALGGSQVNKPRLL
                     RTVLGAKVSQITAGELVDADNRVISGSVLNGAIAQGAHDYLGRYHNQISVIEEGRSKE
                     LFGWVAPQPDKYSITRTTLGHFLKNKLFKFTTAVNGGDRAMVPIGTYERVMPLDILPT
                     LLLRDLIVGDTDSAQALGCLELDEEDLALCSFVCPGKYEYGPLLRKVLETIEKEG"
     gene            complement(15797..17218)
                     /locus_tag="ACFOV4_000913"
     CDS             complement(15797..17218)
                     /locus_tag="ACFOV4_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HFC7618949.1"
                     /translation="MRHLPLFSLMLFPASVYAADLDGANLNLLWGLPFALILLSIALG
                     PLFFSHTWHHHYGKITAFWTLLFLIPFSLVFGASAGIHTVAHALVEEYIPFILLLLAL
                     YTISGGILVWGDLNGTPKLNTALLAVGTALASIMGTTGAAMLMIRPLLKANQNRTRRV
                     HIVIFFIFLVANIGGGLTPLGDPPLFLGFLKGVDFMWTVKHMFAPVLISTAVLLTAFY
                     FIDNRFFKQESIAQDTPAQQEKPEKIAIFGKWNFLLLSGVVGAVLMSGLWKPEHPGFE
                     ILGSRYALQNLVRDVILIALTAVSMAITPKQVRAGNEFNFEPIAEVGKLFLGIFITIF
                     PVLSILKAGEAGALGGVVSLVHDTAGHPINVMYFWMSGILSAFLDNAPTYLVFFNMAG
                     GDAQALMTGTLFHSLLAVSMGSVFMGALTYIGNAPNFMVKAIAEQRGVPMPTFFGYMM
                     WSVAFLTPVFIVHTLIFFVFKLL"
     gene            complement(17576..17935)
                     /locus_tag="ACFOV4_000914"
     CDS             complement(17576..17935)
                     /locus_tag="ACFOV4_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HFC7618950.1"
                     /translation="MIRYLLIACGCISLLLGIIGIFLPLLPTTPFVLLSAACWAKASP
                     RFHRWLHRHRYFGPMVHNWEQNGAVPRKAKIFAISMMTASCLIMFWQFPQRWWVGAVS
                     SVFCSLVAIWMWRRPES"
     gene            complement(17932..18537)
                     /locus_tag="ACFOV4_000915"
     CDS             complement(17932..18537)
                     /locus_tag="ACFOV4_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1415 domain-containing protein"
                     /protein_id="HFC7618951.1"
                     /translation="MTIMNINTSENKDAVAEHTGQWLEKAVIGLNLCPFAKAPHVKNL
                     VRIAISEAKHLDGFLEDLDEELQRLGNTPATELETTLLVHPTLFPDFDVFNDMLDIAD
                     AAVVENGLEGILQIAPFHPQFRFQNTEPDDIGNYTNRSPYPTLHLIREDSIAKAAQAF
                     PDASAIFERNIALLEKMGHEGWAKLGITSCPYPHNKKNISK"
     gene            complement(18584..19066)
                     /locus_tag="ACFOV4_000916"
     CDS             complement(18584..19066)
                     /locus_tag="ACFOV4_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HFC7618952.1"
                     /translation="MPQLTLDKTDIKILQVLQENGRLTNVELSERVALSPSPCLRRLK
                     QLEDAGIVRQYAALLSPESVNLGLQAFIRVSIRKAKDAREDFAASVRKWPEVLSCFAL
                     TGETDYLLQAFFTDMNAFSHFVLDTLLSHHGVQDAQSSFVLKEIKHTTSLPLNHLLKE
                     "
     regulatory      19270..19367
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            19578..20678
                     /gene="gcvT"
                     /locus_tag="ACFOV4_000917"
     CDS             19578..20678
                     /gene="gcvT"
                     /locus_tag="ACFOV4_000917"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HFC7618953.1"
                     /translation="MITLKTTPFHQAHQDAGAKLVDFAGWELPIHYGSQIAEHEAVRT
                     DAGMFDVSHMLVTDVAGANAKAFFRKLIANDVAKLAFVGKALYSALLNDNGGVIDDLI
                     VYRTNEAETQYCIVSNGATREKDTAQFHKVGQEFGVSFNPRYDLGMLAVQGPKAIEKL
                     LTVKPEWADVVNNLKPFQGADLGNDWFVARTGYTGEDGVEVILPGTEAVAFFKALQQA
                     GVQPCGLGARDTLRMEAGMNLYGNDMDDDTSPLEAGMGWTVDLKDESRDFVGKAALLA
                     LKEKGVAVKQVGLLLDKGGILRAHMEVLTDKGKGETTSGVFSPSLKQSIAIARVPKDF
                     DGDTAKVLIRGKEVDVRVLKLPFVRNGQKQFD"
     gene            20840..21226
                     /gene="gcvH"
                     /locus_tag="ACFOV4_000918"
     CDS             20840..21226
                     /gene="gcvH"
                     /locus_tag="ACFOV4_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HFC7618954.1"
                     /translation="MSNNIPAELKYVASHEWLRLEEDGTITVGITHHAQELLGDIVFV
                     ELPEVGANLAAEEQAGVVESVKAASDVYAPIAGEVVAVNEDLPSAPETANSDSYGAGW
                     FFKIKPVNPADYDGLLTAEQYAGEVD"
     gene            21373..22620
                     /gene="hemA"
                     /locus_tag="ACFOV4_000919"
     CDS             21373..22620
                     /gene="hemA"
                     /locus_tag="ACFOV4_000919"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008883 - glutamyl-tRNA reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HFC7618955.1"
                     /translation="MQLTAVGLNHQTAPLSIREKLAFAAAALPKAVRNLARSNAATEA
                     VILSTCNRTELYCVGDSEEIIRWLADYHSLPIEEIRPYLYALDMQETVRHAFRVACGL
                     DSMVLGEPQILGQIKDAVRVAQEQESMGKKLNALFQKTFSVAKEVRTDTAVGENSVSM
                     ASASVKLAEQIFPDIGDLNVLFIGAGEMIELVATYFAAKSPRLMTVANRTLARAQELC
                     DKLGVNAEPCLLSDLPAILHDYDVVVSSTASQLPIVGKGMVERALKQRQSMPLFMLDL
                     AVPRDIEAEVGDLNDAYLYTVDDMVNIVQSGKEARQKAAAAAETLVSEKVAEFVRQQQ
                     GRQSVPLIKALRDEGEKARKQVLENAMKQLAKGATAEEVLERLSVQLTNKLLHSPTQT
                     LNKAGEEDKDLVHAVAQIYHLDK"
     gene            22948..23469
                     /locus_tag="ACFOV4_000920"
     CDS             22948..23469
                     /locus_tag="ACFOV4_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NosR"
                     /protein_id="HFC7618956.1"
                     /translation="MSCFSIKRMSAFRARITAFFAAFVFLTAALPAYAERLPDFLAKI
                     QPSEIFPGADRYGKPEGKPMVARVYKGDEQLGLVYITTDVVNTRGYSSKPIDTLMALA
                     KDGTIAGAKLVDHHESIMLIGIPHLPAPGRAIRSNWLPAYIKPNFTSTNRLRLKGLPT
                     VLQPSKETGAGVP"
     gene            23358..24557
                     /locus_tag="ACFOV4_000921"
     CDS             23358..24557
                     /locus_tag="ACFOV4_000921"
                     /inference="COORDINATES: protein motif:HMM:TIGR04247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide reductase family maturation
                     protein NosD"
                     /protein_id="HFC7618957.1"
                     /translation="MASGVYQTKLHIDKPITIEGPADRSATIEGDRSGRTIAVHAPDV
                     TLRNLTVTRSGMSLPAMDAGIYLEETAPRALIEHNNILDNSVGVYLHGSADAMVRENK
                     IVGDATLRVNERGNGVTVWNAPGAQVVGNDISKGRDGIFSNTSTHNTYKNNRFSDLRF
                     AVHYMYTNDSEISGNISVGNNMGYVLMFSERLKVFDNIAVGSRDQGIMLNYVNYSDIH
                     DNIINKAGKCVFAYNANYDKLSANHFENCQIGIHFTAAIEGTSLHDNSFINNESQVKY
                     VSTRFLDWSEGGHGNYWSDNSAFDLNGDGFGDSAYRPNGIIDQIIWRAPVSRLLMNSP
                     AISIVKWAQAQFPAVLPGGVVDSKPLMKPYAPKIQTRYQAMKDGLLKEAETRQLEWGR
                     AENGSLN"
     gene            24615..25229
                     /locus_tag="ACFOV4_000922"
                     /pseudo
     CDS             24615..25229
                     /locus_tag="ACFOV4_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709597.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            25324..25455
                     /locus_tag="ACFOV4_000923"
                     /pseudo
     CDS             25324..25455
                     /locus_tag="ACFOV4_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688339.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            25452..25946
                     /locus_tag="ACFOV4_000924"
     CDS             25452..25946
                     /locus_tag="ACFOV4_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide reductase accessory protein NosL"
                     /protein_id="HFC7618958.1"
                     /translation="MKKTLLAIVAVSALSACRQAEEGPPPLPRQISDRSVGHYCSMNL
                     TEHNGPKAQIFLNGKPDQPVWFSTIKQMFGYTKLPEEPKGIRVIYVTDMGNVTDWTNP
                     NADTEWMDAKKAFYVIDSGFIGGMGAEDALPFGNKEQAEKFAKDKGGKVVGFDDMPDT
                     YIFK"
     gene            complement(26034..27695)
                     /locus_tag="ACFOV4_000925"
     CDS             complement(26034..27695)
                     /locus_tag="ACFOV4_000925"
                     /EC_number="1.5.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004174 -
                     electron-transferring-flavoprotein dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein-ubiquinone
                     oxidoreductase"
                     /protein_id="HFC7618959.1"
                     /translation="MTESITRDSMQYDVVIVGAGPSGLSAAIKLKQLAEQNGREISVC
                     VVEKGSETGAHSLAGAVIDPIALNELIPDWKEKGAPLTRTVTQDKVLFLTKKKAFNLP
                     ITPNFDNHGNYIVSLGEVVRWLAEQAENMGVEIYPGFAAAEVLYHEDGSVKGIATGNM
                     GVGKDGEPTDSFQPGMELWARQTLFAEGCRGSLSKQIIERFKLDQNSQPQTYGLGMKE
                     VWEVPSEQHQPGLVVHSAGWPLDSKTYGGAFVYHFDDNKVAVGFVVGLDYQNPYLSPF
                     EEFQRFKTHPEIRKTFEGGRRIAYGARSLIEGGLQSLPKLSFKGGVLIGDAAGFLNMP
                     RIKGIHTAMKSAMIAAEAVFPLLEHLEEAEGFDSGKEAADYQQRFEQSWLYRELYAAR
                     NVRPSFKWGVYLGSIYTGIDQMIFRGKAPWTLKHYGKDNEQLKKAAACKPIDYPKPDG
                     VLTFDRLSSVFLANLAHEENQPDHLVLNNPQTMIDVNYKEYASPETRYCPAGVYEIVE
                     ENGNPRLQINAANCVHCKTCDIKDPTQNITWICPEGASGPNYGGM"
BASE COUNT         6618 a         6786 c         7622 g         6896 t
ORIGIN      
        1 gttggaatat agggttaaaa tagggctctt ttgggcttat tcaaattagg gacacgccct
       61 aattattttt tgtcgtcttt tacttcttca aagtcggcat ctacgacatc atcgtctttc
      121 tttgcagaag cattggcttg ttcgctttcg cctgcttggg cttcagcttg tgcttgagcg
      181 taaaccattt cccccagttt ttggctggct gcgcccagcg cctcggtttt ggcatcgata
      241 gcggctttgt cgtcgccttt aactgcttct tcggcttctt tcagcgcggc ttcgattttt
      301 tctttctcgg ctgcgtcgag tttgtcgccg tagtcggcca aagatttttt cacagagtga
      361 atcagggctt cggcttggtt gcgggaagcg accaattcag tcagtttttt atcttcctcg
      421 gcattggctt cggcatcttt caccatgcgt tcgatttctt cttcgctcaa acctgaagaa
      481 ccttggatgg tgatgttggc tgctttgcca gtgcctttgt ctttggcgga aacgtgcagg
      541 ataccgttgg cgtcaatatc gaaggtgact tcgatttgcg gcataccgcg cggtgcgggt
      601 gcgatgtcgc ccaagttgaa ctgacccaaa gatttgttgg cagaagcgcg ttcgcgttcg
      661 ccttgcagta cgtggatggt tactgcgctt tggttgtctt cggcggtaga gaacacttgc
      721 gacgctttgg tcgggatggt ggtgttcttt tgaatcagct tggtcatcac gccgcccatg
      781 gtttcgatac ccaaggacag aggggttacg tccagcagca atacgtcgct gcggccgccg
      841 cttaacactt cgccttgaat cgctgcgcct acggcgacag cttcgtcagg gttcacgtct
      901 ttgcgcggct ctttgccgaa gaagtcttta acggcttctt gtactttcgg catacggctt
      961 tgaccaccga ccaaaatcac gtcgtcgatg tcgccagtgc tcagaccggc atctttcaat
     1021 gcggtgcggc aaggctcgat agagcgggca atcaggtctt caaccaggct ttcgaatttg
     1081 gcgcgggtaa ttttcatcgc caagtgtttc gggccggttg cgtccatggt gatgtacggc
     1141 aggttgattt cggtttgctg gccgctggac aattcgattt tggctttttc ggcagcttct
     1201 ttcagacgtt gcagagccat gacgtcttgt ttcaaatcaa tgccttgttc ttttttaaac
     1261 tcgtcaatga tgtagtcgat caagcgttgg tcgaagtctt caccgcccaa gaaagtatcg
     1321 ccgttggtag ccaatacttc aaattgtttg tcgccgtcga ggttggcgat ttcgatgatg
     1381 gaaatatcga aagtaccgcc gcccaagtca tatacggcta ctttgcggtc tttgttgtcg
     1441 cctttgtcca taccgaatgc caaagcggct gcggtcggct cgttgatgat gcgttttacg
     1501 tccaaaccgg cgatacggcc tgcgtctttg gtggcttgac gttggctgtc gttgaagtag
     1561 gccggaacgg taatcacggc ttcggttact ttttcgccca agtaagcttc ggcggcttct
     1621 ttcattttac gcaggacttc tgcggaaatt tgaggaggag acagctcttt gccttgtgct
     1681 tttacccatg cgtcgccgtt gttggctttg atgatttcga aaggcataga ttcgatgtcg
     1741 cgttggactt ctttgtcttc aaatttgtgg ccgatcaaac gtttggcggc gtaaatagtg
     1801 tttttggcgt tggttaccgc ttggcgtttg gcaggcgcgc cgacgaggat ttcgccgccg
     1861 tccaaataag cgataacgga cggcgtggtg cgtgcgcctt ctgcgttttc gataactttg
     1921 gtttgaccgt tttcggaaat ggccaaacaa gagttggttg tacctaagtc gataccgatt
     1981 acttttgcca tgtggataat cctatttgat tttgcttatt ttgagaaata tgttggaaca
     2041 ttttgtcccg atgggctgta aatagggcgg gcggcgggct gtttcaagct acagcatggc
     2101 tataagtata taactttatg aatatattgg ttttatattt gatttaatac atttggctcc
     2161 aatgcattca agcataatat ttcaaatggc aggcaggttt attcgtagac gatgccggcg
     2221 agcatttcct gttcgttcaa gttgccgtac tctttttccc agtcgtgtga agactcgatg
     2281 atgtcgcatt ctttggaaag ggagacttgt tctgcatcca tatctttggc gttcagtatg
     2341 ttgaattgtt cgcacaggga tgcggataaa gtgatgtcgg gctgtttggc ttcagaacgg
     2401 ttttcttgga aggcaaagca gaatgcggta aatgccgcag tatagataag atatttgccg
     2461 gttttcttca tttttctatc ctttttctgt caattcagga ttaaacctat ggaaaaatct
     2521 gaaaaattat gtattaagta agaaaaatca taatttaaat ttagtttatc ataattgttc
     2581 cgttttttgg atagctaagg taaaatatat ttcatgttta ctttagatga ttgaatgaag
     2641 gggagtggaa ggatatttat ggaaaccttt aaagacagac tggttttttt atggaaaagc
     2701 gaagcgaggc aggcaaaaat cgcatccgat attgaaatga cgattgcggg cttcagcagg
     2761 atatggaatg aaggcggtct gccaaagtct gaaacattga aaaaaatcaa gcagttgaag
     2821 gggtgtagta tcgattggct gctgaccggg gagggtaatc cgtttccgga tgaagcccca
     2881 aaaaaatccc ttgcttacga tactttgggc aatgaagtcg atacggacga gtttgtcttc
     2941 gtgccgagat atgatattcg ggcggctgcg ggatacgggc agtttgtcga tcatgaggaa
     3001 ccggtattta caatggcgtt cagacggcat tggattgaga attatgttac ccgcgatacg
     3061 aaaaacctgt ctgtaatttc cgtcaagggg gattcgatgg agggggtttt gaatgacggc
     3121 gattcgattt tggtcaatca tggtgaaaat acgccgaggg acggtctgta tgtgttgcgg
     3181 attaatgaaa atctgctggt taaacgttta cagattgtac cgggcgggat tatcaatgtg
     3241 atttctgcaa acgaggctta tcctgctttt gaaatcaatt tgaacgattt gaccgatgat
     3301 gtggagatta tcgggcgtgt cgagtggttc ggcaggacga tttgagtttg gggcttgaaa
     3361 ttgcaggcgg tcaaacttat ctattggaac aattcctttt tcaaaggcga agcctgcttg
     3421 cctttgaagg gggtttgaga gagaatgcag aaaatattat attaaggaat aacaccatgt
     3481 cggatgaaag ccctattatt tttactgaca gctgctgtgc caaagttgcc gatttgattg
     3541 ccgaagaaaa caatcccgat ttgaaattgc gggtttttgt caatggcggc ggctgttcgg
     3601 gtttccagta cggatttact tttgacgaaa tcaaaaacga cgacgatttt gaaattgaga
     3661 aaaacggttt ggtctttttg gtcgatccga tgagctatca atatctggtc ggtgcggaaa
     3721 tcgactatac ggaaagtttg cagggttcgc aattcgtcat ccgcaatccg aatgcggaaa
     3781 caacctgcgg ttgcggatcg tcgttttccg tatgaccgct tggtttgtgt gatgccgtct
     3841 gaacgttcag acggcatttt tacttttaga aaatatatta tcgggatgaa ttcacatata
     3901 atccgattgt ttgaagatga atcgggtttc ccgaaaggaa cgggcggaac ggtatcaggc
     3961 gtatttgttc ccttatgatt gagatgagta aagattaccg aaacgatttg tacgatgtat
     4021 atgtttctta cccgccccaa gtggatcgcg ggcttatccg ggagtgcctt aaggagaatc
     4081 tcggcgagga aaaggcggaa ggattgatcg aatcgctcga ttccaaacct caagtgctgg
     4141 ttgaggaaaa atgcacttgg gcgaaacggg aagagttgca tgattatttc agctatttgg
     4201 gtttggatat tattacccgg agatatatgg agttggaaac ggtcgtgccg ccggaggaag
     4261 gggagggcga aggagaaggc gcggatgggg aaatgcccga atatcttgaa cttcacggcg
     4321 ggcgggaaga tgatatttcc gcaccttcgc aacccgaacc gccgtcccgc aatatcaaac
     4381 tgctggtttt cgggctgctg attgcctttt tgggctatct gctcggtaag attttttgat
     4441 tgtccgataa atgctgtatt cgggatttta tatatgaaat ggttgaaacg cctgacggtt
     4501 attgtcggga ctttttaccg ctatcggctg gcaggtctgt gtgcttcgct gatgggtagc
     4561 ggttggatat gcgctctgct gaaaatgatg ccgcagtcgt ccaaattgaa aaacgaaccg
     4621 cctgctgtcc gtctgcgcct tgccttggaa agcctggggc cgattttcat caagttcggg
     4681 caggttttgt ccacacgccc cgatttgatt ccgcacgatt acgccgtcga actggcaaag
     4741 ctgcaagaca aagtgccgcc ttttgacgcg cggctttcgc gtgaacaaat cgaaaaatcg
     4801 ttgggtcagt ccatcgaaaa gctgtatgcg gaatttgaaa ccgagcccat cgccagcgcg
     4861 tccatcgccc aagtacacaa agcccgcctg cattcgggcg aacgagtggc ggttaaagtt
     4921 ttgcgcccca accttttgcc ccttatcgaa caggatttgt cgctgatgcg tttcggcgcg
     4981 gcctgggtcg aacgcttgtt ttcagacggc aggcgtctga agccgctcga agtggtggcg
     5041 gagttcgaca aatacctgca cgacgagttg gatttgatgc gcgaagccgc caatgccgga
     5101 cagctcgggc gcaatttcca aaacagcaat atgctgattg tgcccaaggt gttttacgac
     5161 tactgcacca gcgacgtgct gacaatcgaa tggatggacg gcacgccggt tgccgacatc
     5221 gccaaactca aagcagacgg catcgatttg cacaaactcg ccgattacgg cgtggaaatc
     5281 tttttcacgc aggtcttccg cgacggcttt ttccacgcgg atatgcaccc cggcaatatt
     5341 ttggttgccg ccgacaaccg ctacatcgcc ctcgatttcg gcatcgtcgg cacgctgacc
     5401 gattacgaca aacgttatct cgccatcaat ttcctcgcct ttttcaaccg cgattaccgg
     5461 cgcgtcgcca ccgcccacat cgaatcgggc tgggtgcctg ccgacacgcg tgcggaagaa
     5521 ttggaagccg ccgtccgcgc cgtgtgcgaa ccggtgttca acaaaccgat ttcgcagatt
     5581 tccttcggct tggtgctgat gcgcctgttt gaagtcagcc gccgcttcaa tgtcgaaatc
     5641 caaccgcagc ttgtgctgct gcaaaaaacg ctgctcaaca tcgaaggctt gggccgccag
     5701 ctcgatcccg atttggactt gtggaaaacc gccaaaccgt ttttggtgaa atggatgaac
     5761 gggcaggtcg gccctaaagc cctttggcgc aacctcaaaa acgaagcccc cgactgggcg
     5821 caaatcatcc cttcattgcc gcgcaaaatc agtgcgttga ttgatgaaaa ccgccagcag
     5881 gaaatgcgtg atgcctatat ccatttggtc aaagtgcagc agcggcaaag cctgtggctg
     5941 gctgtgattg cggttgtttt gctgctgatt ttgcttttga aataggcttt gtccgaatca
     6001 tcgcccgact ccgcccgttt ataaggaaat cggttatagt ggattaacaa aaaccagtac
     6061 ggcgttgtct cgccttagct caaagagaac gattctctaa ggtgctgaag caccaagtga
     6121 atcgattccg tactatccgt actgtctgcg gcttcgtcgc cttgtcctga tttttgttaa
     6181 tccactatat ttccggttgc gtgggaatcg ggtgtattga ataaaaggca ttttgtccga
     6241 ctggcaagtg ccgacatcgg cggcatatca aggcgcaggc ttgaagcggg caatgtcgtc
     6301 tgaagcccgt ttggcgtttc agacggcatt ggtgcggata ttcaaatcat aaagtcgatt
     6361 tcggtaaact ggatattttg atccatatcc gccgacggtg ttttgagcga tcgcgccacg
     6421 ggtttggcgg gtacgccgac aaccgtgatg gacggcggca cgtctgaaac cacgacgctg
     6481 cccgccccga ttttggcatt gctgccgatg cggatattgc ccaatatcga ggcgtttgcg
     6541 ccgatcatca cgccgtcgcc gattttaggg tggcggtcgc cgccttcttt gcccgaaccg
     6601 ccgagcgtta cgccgtgcaa aatcgaaata ttgttgccca acacggcggt ttcgccggca
     6661 acaaagccgg tggcgtggtc gagcatcagc ccgtatccga aacgggcggc gggatggatg
     6721 tccacgccga atacttcgga catacggttt tgcaggaaat acgccagcgt tttgcgcccg
     6781 tcgagataca gccgatggtt gatgcggtgt gcctgaatcg cgtggaagcc tttgaaatat
     6841 aaaagcggca gcgaatattc gtcgcaggcg ggatcgcgtt cgtagatggc ttttaagtct
     6901 gcttcgacgc atttgccgat ttgggtgtcg ctgcccaacg cctgctggta gatttcaaac
     6961 agcgcgcgca cgtccataat cgggctgccg agtttgctgg aaaggtggta ggcaaggacg
     7021 gagccgaggg actcgtggcg caacacggtt tggtgcaaaa aacttgccag catcggttcg
     7081 gcggagaccg cggccgcggt ttcttcgcgg atggtgtgcc agaggtcgaa accggttgtg
     7141 tttaaatggt cttttttcat gagtgatgac gtttgaaaat cgatatggtc ggcagtatct
     7201 taccgtctat attatttttt cggtagggga tttgaaaatg aatttgaaat tctctgcttt
     7261 tgcttgaagt ttcttgaaaa tgtccttatc ttgcgcgggt aataactgga ttttgatttc
     7321 caatttgttt taagggatac gatatgagcg aacagacaca gcagcaaaac agtgaagaag
     7381 cggttgaaaa tgtggaggcg gtggaaaccg tcgagacagt aggaaatgcg gacggtgtgc
     7441 aggaacaggc tgccgcagag ccggcttatg aggatttgca ggcgcggatt gccgagctgg
     7501 aagcgcagtt gaaagacgag cagctgcgcg ctttggcaaa cgagcaaaac ctgcgccgcc
     7561 gccaccagca ggaaattgcg gatacgcaca agttcgccgg acagaagttt gccgtggaaa
     7621 tgctgccggt caaggattat ctggaaatgg cgcttttgga tcagagcggc aatttcgatg
     7681 cgctgaaaat gggcgtgcag atgactttga acgagttgca gaaagcattt gatgctacgc
     7741 aaatcaagga aatcaaccct aaagcgggcg ataagctcga tccgaatatc catcaggcga
     7801 tgcaggcggt ggcaagcgaa caggagccga ataccgtggt gggtgtgatg aagaagggtt
     7861 atacgctgtc cgaccgcgtg ttgcgcccgg ctatggttac ggtggcgcag aaggaagcct
     7921 gaaggcgtct ggggaataat ctgatttatt tcctgaagcg cgttttgcgt ataaaccgat
     7981 cgaagtaaag cggcaatgcc gtctgaaccc gcctgtcggg cttcagacgg cattttatag
     8041 tggattaaca aaaatcagga caaggcgacg aagccgcaga cagtacagat agtacggaac
     8101 cgattcactt ggtgcttcag taccttagag aatcgttctc tttgagctaa ggcgaggcaa
     8161 cgctgtactg gtttttgtta atccactata tttcggcgtt aacggtcaac ccgtatgccg
     8221 cctgcctgtt tttcttcatc cagtttcttt tgcagggtgt cgcaaggtgt gtcgcagtcg
     8281 cacatttttt tcatacccaa ggcagtaatg ccgccgcaac tgcctttgat gctgcgtttg
     8341 gagaaaatat agccgaccgc cataccgatg atgacggtca ggaagatgcc gaaggtaagg
     8401 agcagggttt tcatggtgtt tcctaatcgg tttgtatgtt tagcggagca gtttttcaaa
     8461 ttcggaagac atggcggtgc ggtagccgcc tttatccctg acaatcagga aaacagcgag
     8521 tttttcgcgc tctgccagct ttaaggcttc ggtttcgccc aatacgaata atcctgtgga
     8581 caagccgtcc gccgtcatcg cactgtctgc gaccacgctg atggaggcga ggttgtggct
     8641 gatgggtcgt ttgttgttcg ggttgatgat atgggagagg cgtttgccgt ttttatcgac
     8701 gtggaaaata cggtaatcgc cggaagtggc aagcgaacgg ttgttcagcg ggacgataat
     8761 ctgcgtattg ccgccttgga cgatattggg ctgctcgata ccgatgcgcc acggttcgcc
     8821 gcgcgcgttt ttgcctttgc cgtgcaactc gccgccgatt tcgaccagat aattttgaat
     8881 gccgtatttt tccagttcgc ccgcaacttt atcaacgccg aagcctttgg caatcgaaga
     8941 taaatccaaa taggccttgg ggtgggtttt gctcaaggaa gcgtaatctt tgccttgttt
     9001 caaaatgatt ttgtctatgc ccgtataaga tgccgcctgt ttgatttgtt ccggcgacgg
     9061 ttcacgggta acggatttgt cggggccgaa tccccaaagg ttgaccaagg ggccgacggt
     9121 tacgtccagc gcgccgtgtg tcaggcggtt caggcggacg gcttcggcag taacgtgtgc
     9181 gaagtcgctt gaaatgcgga ggggcttgcc ggctgtgtgt tggttgaacc ggctgatttc
     9241 ggagtcgggc tgataggtgg acatctgccg gttgacttct ttaagcgcgt catcgatgcg
     9301 tttttgtatt tcggcaggtg aggggagttt gtcccgatta tttgaaaggt atttgacggt
     9361 ataggtcgtg cccatcgttt cgccttgcag ggtaacggtt tgcgcggttt gttccgaaca
     9421 ggcgttcagg aagatgaaac ccagggcaaa tatcaagacg cggataaagt tcggcaggcg
     9481 tgtttcagac ggcatagtgt ttgacggttt tggcaaatgg tttgaattat atcgcaaaac
     9541 ggccggtatg tttctatgcc gatgccgtct gaagggtgtt cggatggcat cggcatagaa
     9601 aaaggaagaa accgaggttt cttccttttg tatttgaagc cgaatattta accgccgaaa
     9661 tcgtccaaga ggatgttttc gtcttccacg cccaagtctt tgagcatttt gatgacggac
     9721 tggttcataa tcggagggcc gcacatataa aattcgcagt cttccggtgc ttcgtggttt
     9781 ttcaggtggt tttcgtaaac cacgttgtga atgaagcccg tgtagccgtc ccagttgtct
     9841 tccggcagcg ggtcggacag ggcgacgtgc cacgtgaagt tcgggaactc tgccgcgagt
     9901 tggtcaaagt cttcgacata gaacatctcg cgtttggaac gtgcgccgta ccagaaggta
     9961 atcttacgtt tggagttcaa acgtttcaac tggtcgaaaa tgtgggaacg catcggagcc
    10021 atacccgcac cgccgccgat aaataccatt tcggcatcgg tgtctttggc gaaaaattcg
    10081 ccgaacgggc cggaaatcgt aactttgtcg ccgggtttga gcgaccagat gtaggacgac
    10141 atttgtcccg gaggcgcatc aggtacgcgc gggggcggcg tggcgatacg cacgttcagc
    10201 ataatgatgc ctttttcttc aggatacgaa gccatagagt aggcacgcaa aatcggctcg
    10261 tccactttgg aaacgtattg ccacaaattg tatttgtccc agtcttcgtg atattcctta
    10321 ggaatgtcga agtctttgta ggcaacagtg tgaggaggag cttcaatttg aatgtagccg
    10381 ccggcgcgga aggggacttc ttcgccttcg ggaatggcaa gcttgagttc tttaatgaac
    10441 gtggctttgt tatcgttgga gatgacggtg cattcccatt ttttcacgcc gaacacttct
    10501 tcgggcactt cgatgtccat gtcggttttg acgctgactt ggcacgacag acggcagcct
    10561 tcgcgtgctt cgcgtttgct gatgtgggac agctcggtcg gcaggatgtc gccgccgccg
    10621 ctttttacga cgacgcggca ttgtccgcac gaaccgcccc cgccgcaggc ggaggggata
    10681 aagatgcctt cgttggcaag cgcgcccaag agtttgccgc cggcgggcat cgtcagctct
    10741 ttttcgccgt tgactttgat ggtgatgtcg ccttcgctga ccagtttgga tttggcaaat
    10801 agaatcatca gtgccaaaac caaaacgatg acggtaaaca tcacgatacc taaaataatc
    10861 tccataccgg tccctttctt ataactggat gccggagaac gacataaacg ccatcgccat
    10921 caggccggcg gcgataaagg taatgcccaa gcctttgagg cctttgggag cgtccgaata
    10981 tttcattttt tcggtaatgc ccgccaaagc gacaatcgcc aacatccagc ccaagcccgc
    11041 gccgaagccg tatacaacgg actcgccgaa gttgtattcg cgttgcgcca taaacgatac
    11101 ggcgccgaaa atcgcgcagt tcacggtaat cagcggcagg tagatgccca acgcgttata
    11161 gagggcgggg acgaatttat ccaagaacat ttccaaaatc tgcaccaaag cggcaatcac
    11221 gccgatgaag gtgatgaatt tcaaaaaggt caaatccacg ccttcgacaa tcgcgccgtc
    11281 tttgagcagc gagtaaacga gttggttgac agggacggac agcccgagta cgaaaattac
    11341 cgccacaccc aaaccgaatg cggtggatac ttttttggat accgccaaaa acgtgcacat
    11401 acccaaaaag aaggatagtg ccatattttc aatgaagacg gatttgatga agaggctcaa
    11461 atagtgttcc atagcttatt cctccgcctg ttcgggtttc caggtacgca gtccccaaat
    11521 caaaaagccg atgatgaaga acgcgctggg ggcgagcagg aacaagccgt tggtctgata
    11581 ccagccgccg tcctgcacgg tttggaaaac ggtgtagccc aagagtttgc ccgagccgat
    11641 cagttcgcgg acggtggcga cgacaagcag catcatcccg tagcccgcgc cgttgccgat
    11701 gccgtcgatc aggctttcca gcggcggctc tttcatcgca aatgcttcgg cgcggcccat
    11761 cacgatacag ttggtaataa tcagaccgac gaatacggaa agctgtttgg acaattcgta
    11821 ggcaaatgcc tgcaagagtt ggtcgaccag cgtaaccagc gacgcgataa tcgccatttg
    11881 cacgataata cggatgctgt tggggatgta gttgcgtacc agcgaaatga agaagctgga
    11941 aaaaccggtt accaaagcta cggaaatacc catcacgatg gccgtctgaa gtttggtggt
    12001 aaccgccaaa gccgaacaaa tacccaaaac ctgcaaggca atcgggttgt tgtcgataaa
    12061 gggtgaaaac atcaaatgtt tcaagcgttt catatcagcc attattgcgc tcctgctgat
    12121 ttcaatttgt tcaggtaggg gatatagccg ttttcgccga accagtaggc gaacgaacct
    12181 tgcacgcctt tggatgtcag cgatgcgccg gagagggcat ctacgccgtg ttctttgtcc
    12241 gaacccgcgc ctttgccgac gtgcagggcg agtttgcctt gtccgtcaaa cagttttttg
    12301 ccgacgaatt tttgctgcca caacggattg ccgatttcgc cgcccaagcc cggggtttcg
    12361 ccttgttcgt agtaggtaat gccgttgatg gtgttgccgt cgggctggat ggcgacaaag
    12421 ccgtacatga ccgaccacaa accgttaccg tgcataggca ggatgatttg cccgattttg
    12481 ccgtcttcgc cttttaccaa ataaacctcg gtgtatttgg cacggctttt gatgcctgcc
    12541 aaatcgtctt cgggtttgat gcggatgctt tgggcagggt ctttgcctgc gatgcgcgcg
    12601 ctgaagtctt taggcgcatc ggcgacgtat tcgccggtcg ccaaatcgac aacacgttgc
    12661 tcgatacgct cggcaaaggt tttaccgatg tcggtgtcct tatccatcaa accggctacg
    12721 ctcaagatat agccttgttt gtcttggagt ttttgtttct cttggatggg tttcaagccg
    12781 acgaccgcac cggcaacgat gaccgagcaa atcaggctga ccgccaacac gacaatcagc
    12841 gtaccgctga agctgtcttt atcgaatttc ttagccattg ctgcgcgcct ttctgcgttt
    12901 gatgttcgct tgtgcgacga aatagtcgaa aatcggggca aacaggttgg caaacagaat
    12961 cgccaacatc atgccttcgg ggtaagccgg attgaccacg cggattaata cgcacatcac
    13021 accgatcagt gcgccgtacc accatttgcc gacattggta aaggaagcgg aaacggggtc
    13081 ggtcgccata aacagcatac cgatggcgaa gccgccgacg accaaatgcc agtaccaagg
    13141 catagcaaac atagcgttgg tgtccgaacc gatgaagttg aacagcgaag acatcgcaat
    13201 cataccgatc atcacgccgg caataatgcg ccaagaagcg atgcgggcaa acacgataaa
    13261 cgcgccgccg attaagagtg ccaaagtgga gacttcgccg atggagccgg gcagtttgcc
    13321 gataaacgcg tccatccaag tgatggtttg accggttacg gcgtttttca ggccgtctgc
    13381 accgtgtgcc gcccattgcg ccagcgcggt tgcgccggaa tagccgtcaa ccgccgtcca
    13441 aaccgcatcg ccgctcaagt tggcggggta ggcgaagaac aggaaggcgc ggcctgccag
    13501 cgcagggttc ataaagtttt tacccgtacc gccgaatact tctttcgcaa ccacaacgcc
    13561 gaaagaaata cccaaagccg cctgccacag cggcagcgtg ggcggaacga ttaaggcaaa
    13621 cagaatcgag gtaacaaaga aaccttcgtt gatttcgtgt ttgcgcacgg tggcgaacaa
    13681 gacttcccag aaaccgccga cggcaaatac ggtcgcgtaa atcggcagga agtaaatcgc
    13741 gccgaacagc attttgccca acacgctcgc ttcagacgac atattgatgc ccaaagcgtc
    13801 ggcaagggtg taatgccagt cgttggcgat gttttgttgc agcaaatcag gcgttaacgc
    13861 accgaatgcc tgtacgccga cgttgtacat accgtagaac atggcaggga acaaagccag
    13921 ccacaccaaa atcatcatgc gtttggagtc gagcgcatcg cggacgtgtg ccgctttgcg
    13981 cgttaccgca ccggatgtat agaaaatcgt cgccgcagct tcgtagaggg cataccattt
    14041 ttcatgtttg ccgcctggca ggaagtgcgg ttcgattttt tccagaaaat gtttcaagcc
    14101 cataatcagc cttccttctc aatggtttcc agcaccttac gcaacagcgg gccgtattcg
    14161 tatttgcccg ggcagacgaa gctgcacaaa gcgaggtctt cttcgtccaa ttccaagcaa
    14221 cccaatgcct gcgcgctgtc ggtatcgccg acgattaaat cgcgcaaaag cagggtaggc
    14281 aggatgtcta gcggcattac gcgctcgtaa gtaccaatcg gcaccatggc gcggtcgcca
    14341 ccgttgacgg ctgtcgtgaa cttgaagagt ttgtttttca ggaaatgacc gagggtcgta
    14401 cgcgtgatcg agtatttgtc cggttgtggc gcaacccagc cgaacagttc tttactgcgg
    14461 ccttcttcga taacggaaat ctgattgtgg tagcgtccca aataatcgtg cgcgccttgt
    14521 gcaatcgcgc cgttcaatac cgaaccggaa atcacgcggt tgtctgcgtc aaccaattcg
    14581 cccgcagtaa tttgcgatac tttcgcaccc aaaacggtac gcaagaggcg tggtttgttg
    14641 acttgagaac cacccaaggc aaccacgcgc tcggtgttca gacggcctgt tgcaaacaaa
    14701 cgtccgatgg caattacatc ttgataattg atggtccaaa cggttttgtt cgcaccgaca
    14761 ggctcaatga aatgaatgtg cgtgccactc aaaccggcag gatgcgggcc gccaaattca
    14821 tgagtttcga tgttggcggc gttttcagac ggcacgtctg cgcctgctgc tttacacaca
    14881 tggattttac gctcggtcaa acggctcaat accagcaaac ctcgtctgaa atcctcggcg
    14941 gcttctttga tcacaaccac agggtctgcc gccagcggat tggtgtccat cgcattgacg
    15001 aagatggcga acggcgcggc atcgacggca gggattttgc tgaacggacg ggtacgcagc
    15061 gcagtccaca aaccggattg gatcagattg cggcgcactt cttcgccgct taagtttgcc
    15121 aacgcttcgg gtgcgtagcg ttcaaactcg atttcgtcgt tgccttcaac ggcaatcacg
    15181 actgactgaa gtacgcgctt ttcgccgcga tggatggcgg cgattttgcc agaagccggc
    15241 gcggtaaaca ccacgcccgg attctttttg tcttcaaaca gcacttggcc ttttttgacg
    15301 gcatcgcctt ccttgacttt catcgagggg cgcataccgg catattcttc gccaagcaac
    15361 gcgacttcgg taatggccgg gccgtcataa atgacttgct ccggtctgcc cgcgatgggc
    15421 aggtttagac cttttttgat tttaatcata tatttgcatt acttgtgatg gttaaggtaa
    15481 aaacggcgtg ttttgatacc gtgtcgcgtg gcatcaaaag cattgaataa attaatgtag
    15541 caaagtgtta gattctatca ggaattgtac ctgtttgtca gatttgctgc ttttttcctt
    15601 gcggaagccg tttttatagt ggattaaatt taaaccagta cggcgttgcc tcgccttgcc
    15661 gtactatttg tactgtctgc ggcttcgtcg ccttgtcctg atttttgtta atccactata
    15721 attgtcggaa ggggggatat tgatttgatt atgccggaat ttaaaatgcc gtctgaatgt
    15781 tcagacggca tagcgtttac agcagtttga aaacgaaaaa gataagggta tgtacgatga
    15841 agacgggtgt caggaaggcg accgaccaca tcatatagcc gaagaaagtc ggcatcggta
    15901 cgccgcgctg ttcggcaatg gccttgacca tgaagttcgg tgcgttgccg atgtaggtca
    15961 gtgcgcccat gaataccgaa cccatagaaa ccgccagcag cgaatgaaac agggtacccg
    16021 tcatcaaggc ttgggcatcg ccgcccgcca tattgaaaaa aacgagataa gtgggcgcgt
    16081 tatccaagaa tgccgacaat atgccgctca tccaaaaata catcacatta atcggatgac
    16141 ctgccgtatc gtgaaccagc gataccaccc cgcccagcgc gcctgcctcg cctgctttca
    16201 gaatgctcag gacgggaaag atggtgatga agatgccgag gaagagtttg cccacttcgg
    16261 cgatgggttc aaagttgaat tcgttgcctg cgcggacttg tttgggcgtg attgccatag
    16321 atacggcggt caatgcaatc aggatgacat cgcggacgag gttttgcagg gcgtaacggc
    16381 tgccgaggat ttcaaatccc gggtgttcgg gtttccaaag gccggacatt agaaccgcgc
    16441 cgaccacgcc cgaaagcagg aggaagttcc atttgccgaa gatggcgatt ttttcgggtt
    16501 tttcctgttg tgccggcgta tcttgtgcaa tgctttcctg tttgaagaaa cggttgtcga
    16561 tgaaatagaa ggcggtcaac aggacagcgg tgctgatcag gacgggggcg aacatatgtt
    16621 tgaccgtcca catgaaatct acgcctttga ggaagccgag gaagagtggg gggtcgccca
    16681 aaggggtcag accgccgccg atgtttgcaa ccaagaaaat gaagaagatg acgatgtgca
    16741 cgcggcgggt acggttttgg ttggctttca gcagcggacg aatcatcagc attgctgcgc
    16801 cggtcgttcc catgatagag gcaagtgcag taccgacggc aagcagggcg gtgttgagct
    16861 tgggtgtgcc gttcaagtcg ccccaaacca aaatgccgcc tgaaatggtg tacagggcaa
    16921 gcagcagcag gatgaagggg atgtattctt caacgagtgc gtgtgcgacg gtatggatac
    16981 cggcggacgc gccaaaaacc aaactgaacg ggatgaggaa gagcaatgtc caaaaggcgg
    17041 taattttgcc gtaatggtga tgccaggtat gcgaaaaaaa caagggaccc aatgcgatag
    17101 acagcaaaat cagggcaaag ggcaggcccc acagcaggtt taggtttgcg ccgtccaaat
    17161 ctgcggcgta aaccgatgct gggaaaagca ttagtgaaaa caggggtagg tggcgcatcg
    17221 tgtttcctcg attcaagcac tgccttgcgc ggcgcgtggg agtgatacag gcaccgtgcc
    17281 gcccggacat aggcggactg tgctgcctgt ttgtttttga aaaaagtttt ccgattgatt
    17341 gtaaagtaaa taatcaggat aaaccagttt cccaaaccgg aaggcggcgg gaaggcggat
    17401 tgccgtgctt gggaatatat gttctttttg ataaataatt ttatttaaaa caaataaata
    17461 tatgtcttta ataaataatc tatcgaaaac gaaaaatgaa tttattttaa catatatttg
    17521 caatgaaaca ggtttgcccc ccgtttgttt gcccttatcc ctttcagtac ggcattcaag
    17581 attcgggcct gcgccacatc catatggcga caagggaaca aaaaaccgat gaaaccgccc
    17641 cgacccacca gcgttgggga aactgccaaa acattatcag gcaggatgcg gtcatcatac
    17701 tgatggcgaa tattttggct ttgcgcggca ctgcgccgtt ttgttcccag ttatgaacca
    17761 tcggaccgaa atagcggtgc cggtgcagcc agcggtgaaa gcgcggggat gcctttgccc
    17821 agcaggcggc ggagagcagt acgaacggcg tggtcggcaa cagcggcaaa aaaatgccga
    17881 tgatacccaa cagcagggaa atgcagccgc aggcaattaa aagataacgt atcattttga
    17941 aatatttttc ttattgtgcg gataagggca ggatgtgata ccgagttttg cccagccttc
    18001 atgtcccatt ttttccagca gggcgatatt gcgttcgaat attgccgaag cgtcgggaaa
    18061 ggcttgtgcg gctttggcaa tgctgtcttc gcggatcaga tgcagtgtcg gatagggaga
    18121 acggttggtg tagttgccga tgtcgtcggg ttcggtattc tgaaagcgga attggggatg
    18181 gaacggtgcg atttggagga tgccttccaa gccgttttcg acaacggcgg catcggcaat
    18241 atcgagcata tcgttgaata cgtcgaaatc ggggaatagg gtcgggtgaa ccagcagggt
    18301 ggtttccagt tcggtggcgg gtgtattgcc cagtcgctgc agttcttcgt ccaagtcttc
    18361 caaaaaaccg tcaaggtgtt tggcttcgct gatcgcgatg cggacaaggt ttttaacgtg
    18421 gggggctttg gcaaagggac acaggttcag accgatgacg gctttttcca accattgtcc
    18481 ggtgtgttcg gcaacagcat ctttattttc ggaagtattg atattcatta ttgtcatgta
    18541 aatgtgtttg cagattgcac gtgcgggaaa atcgggaagg gcactattcc ttcagcaggt
    18601 ggttgagtgg cagggaggtg gtgtgtttga tttcttttaa aacaaagctc gattgggcat
    18661 cctgtacgcc gtggtgggac aggagcgtat ccaaaacaaa atgggaaaac gcgttcatat
    18721 cggtaaaaaa cgcctgaagc aggtagtcgg tttcccctgt cagggcgaag cagctcaaga
    18781 cttcaggcca ttttcgaacc gatgcggcaa agtcttcccg cgcgtctttt gctttgcgga
    18841 tggaaacgcg gataaatgcc tgaagcccta ggttgacgga ttccggagac agcagcgcgg
    18901 catattggcg gacgatgccg gcatcttcca actgcttcag acggcgcagg cacggagaag
    18961 gcgaaagtgc gacacgttcg gacagttcga cattggtcag cctgccgttt tcctggagaa
    19021 cctgtaagat tttaatatcg gttttgtcta aagtgagttg gggcatattt gcgttccgtt
    19081 ttaaggaatt cggattgtct gtccgtatgt ttgcggcaat ccgcacagat ggagaccata
    19141 ttaacatata aaaagttata ccgtcatccg ggacaaattt tgttttcgga aaatcatgtg
    19201 aaaacagagg cggtcggttt gcatctcttt taagacggct tgcccaaacc gccgattcaa
    19261 gacataatcg ggaaatgtgc aggagagtgt tacacccaac tacaatgtaa ccaccgaagg
    19321 cgcagacacc cttaaatcgc tcaggtatca gggactgcac attgaaacaa acaatctgga
    19381 gagcggcgtt ggaataacgt ccaccgaagg ggagaaggcc gtctgaacca ccattcagac
    19441 aaccgcgcaa agcagtgagc agactggttt gccatcatgc ggatacggcc gaaaatctca
    19501 ggttcaagga cagatagggt catccgcgca caggtgcgcg ggtggcatct gaacaaaaaa
    19561 tccggagaaa cttgagaatg attactctga aaaccacccc atttcatcaa gcccatcaag
    19621 atgcaggcgc gaagctggta gattttgccg gctgggagct gcccatccat tatggttcgc
    19681 aaatcgccga acacgaagcc gtgcgcaccg acgcaggtat gtttgacgta tcccatatgc
    19741 ttgttaccga cgtagcaggc gcaaatgcca aagccttttt ccgcaaattg attgccaacg
    19801 atgtcgccaa gctcgctttt gtcggcaaag ccctttattc cgctttgctc aacgacaacg
    19861 gcggcgtgat tgacgacttg atcgtttacc gcaccaatga agccgaaacc caatactgca
    19921 tcgtgtccaa cggcgcgact cgcgaaaaag atacggcaca attccacaaa gtcggacaag
    19981 agttcggcgt ttctttcaat ccgcgctacg acctcggcat gctcgccgta caaggcccga
    20041 aagccatcga gaaactcctg accgtcaaac ccgaatgggc agatgtcgtc aacaacctca
    20101 aaccgttcca aggcgcggat ttgggcaacg actggtttgt cgcccgcacc ggctacaccg
    20161 gcgaagacgg cgtcgaagtc atcctgcccg gcaccgaagc cgtcgcattc ttcaaagccc
    20221 tgcaacaagc cggcgtacaa ccctgcggcc tcggcgcgcg cgataccctg cgcatggaag
    20281 ccggtatgaa cctctacggc aacgatatgg acgacgacac cagcccgctc gaagcaggca
    20341 tgggttggac ggttgatttg aaagacgaaa gccgcgattt tgtcggtaaa gccgccttgc
    20401 tggcattgaa agaaaaaggc gttgccgtca aacaggtcgg tctgttgctc gacaaaggcg
    20461 gcatcctgcg cgcgcatatg gaagtgttga ccgacaaagg caaaggcgaa accaccagcg
    20521 gcgtattctc tccaagtctg aaacaatcca tcgccatcgc ccgcgtgccg aaagactttg
    20581 acggcgatac cgccaaagtt ctgattcgcg gcaaagaagt ggacgtacgc gtactgaagc
    20641 tgccgtttgt gcgcaacgga cagaaacagt ttgattgatg cggtttcaga cggcattttc
    20701 atttcatatg ccgtctgaaa gcaggtttta attgttgtcc gatacggacg tttgtagaaa
    20761 gcattgaaca aggcatctgt ggatattgat tcatgcagat gccgtctgaa aataacccct
    20821 atcaatggag tatcaaacca tgagcaacaa catcccggcc gaactgaaat acgttgccag
    20881 ccatgaatgg ctgcgccttg aagaagacgg tacgattacc gtcggcatta cccaccacgc
    20941 gcaagagctg ttgggcgaca tcgtgttcgt cgagctgccc gaagtcggcg cgaaccttgc
    21001 cgctgaagag caagccggtg tggttgagtc tgtaaaagcc gcgtccgacg tgtacgcacc
    21061 gattgcaggc gaagtcgttg ccgtcaacga agatttgcca agtgctccgg aaactgccaa
    21121 cagcgattct tacggcgcag gctggttctt caaaatcaaa cctgtcaatc ctgccgatta
    21181 cgacggtctg ctgactgccg aacaatacgc gggcgaagtg gactaaatct ctatcctgat
    21241 aatgggatga ctgatttgag aaactgcact ttcagacggc aaggatgcgt ttggaagtgc
    21301 agtttttgtc tgtgtcttca aagttcagtt aggctataat aacggtctat attcatcttt
    21361 accgattttt tcatgcaact taccgctgtc ggactcaatc atcaaaccgc acctttaagc
    21421 atacgggaaa agctggcgtt tgccgccgcc gccctgccta aagccgtccg caatcttgcc
    21481 cgaagcaatg cggcaacgga ggcggtaatc ctttctacct gcaaccgcac cgagctttac
    21541 tgcgtcggtg attcggaaga aatcatccga tggcttgccg attaccacag tttgccgatt
    21601 gaagaaatcc gtccgtatct gtacgcgctg gatatgcagg aaaccgtgcg ccatgccttc
    21661 cgcgttgcct gcggcttgga ttcgatggtg ttgggcgagc cgcagatttt aggacagatt
    21721 aaggatgcgg tcagggttgc tcaagagcag gaaagtatgg gtaagaaact caatgccctg
    21781 ttccaaaaaa ccttttctgt tgctaaagag gtccgtaccg atactgccgt cggcgaaaac
    21841 tcggtttcca tggcttccgc ttccgtcaaa ttggcggaac agatttttcc cgacatcggc
    21901 gatttgaatg tcttgtttat cggcgcaggc gaaatgattg agctggttgc cacttatttt
    21961 gccgccaaaa gtccccggct gatgacggtt gccaaccgga cgctggcgcg tgcacaggag
    22021 ttgtgcgaca agctcggtgt caacgccgaa ccgtgcctgc tgtccgatct gcctgccatt
    22081 ctgcacgatt acgacgtagt ggtttcttca acggcaagcc agttgcccat tgtcggcaaa
    22141 ggcatggtgg agcgtgcatt gaaacaaagg cagagtatgc cgttgttcat gcttgatttg
    22201 gcagtgccgc gtgacattga agcggaagtc ggcgatttga atgatgccta tctttatacg
    22261 gtggacgata tggtcaacat cgtccaaagc ggcaaggagg caaggcagaa ggccgccgcc
    22321 gccgccgaaa cgctggtatc cgagaaggtt gccgaatttg tcaggcagca gcagggcagg
    22381 cagagcgtcc ccttgattaa agccttgcgg gacgagggcg agaaagcgcg caagcaggtg
    22441 ttggaaaatg cgatgaaaca gcttgccaaa ggcgcaacgg cagaagaggt tttggaacgg
    22501 ctgtccgtcc aactgaccaa caagctgctg cattcgccga cccaaacttt gaataaggcg
    22561 ggggaagaag ataaagattt ggttcatgcc gtcgcgcaga tttatcattt ggacaaataa
    22621 cggtgcgccg gaaaaggatg ccgtctgaag gggtttcaga cggcatattt ttgtgctgtc
    22681 tgacaacatc gtgaaatccc acattatatc gatgtaatca caaagtatag tggattaaca
    22741 aaaatcagga caaggcgacg aagccgcaga cagtacagat agtacggcaa ggcgaggcaa
    22801 cgctgtactg gtttaaattt aatccactat attatcccgt atgcggattg gttttaagat
    22861 ttgtaaattt gatttgcatc aaaaaatcgc cgatagatga ttcatataat atcaatatta
    22921 aagagtatcg gtatatcggg gatagtcatg tcctgttttt caatcaaacg tatgtccgcg
    22981 tttcgggcgc ggataacggc gttttttgcc gcctttgtct ttttgacggc ggcactgccc
    23041 gcttatgcgg agcgtctgcc tgattttctg gcgaaaatac agccttcgga aatttttccg
    23101 ggtgcggacc gttacggcaa gccggaaggt aagcctatgg ttgcccgcgt ttacaaaggc
    23161 gatgagcagc tcggtttggt ctatatcaca accgatgtgg tcaatacgcg cggttattcg
    23221 agcaaaccga ttgatacgct gatggcgttg gctaaagacg gtacgatagc cggagcgaaa
    23281 ttggttgatc accatgagtc gattatgctg atcggtatcc cgcatttgcc cgcgcccggg
    23341 cgggcgatac gctcaaactg gcttccggcg tatatcaaac caaacttcac atcgacaaac
    23401 cgattacgat tgaagggcct gccgaccgtt ctgcaaccat cgaaggagac aggagcgggc
    23461 gtaccatagc cgtacacgcg ccggacgtaa cgctccgcaa cctgaccgtt acccgttccg
    23521 gtatgagcct gcccgcaatg gatgccggta tttatctcga agaaactgcc ccgcgcgccc
    23581 tgattgaaca caataatatt ttggataatt cggtcggcgt ctatctgcat ggttctgccg
    23641 atgcgatggt gcgggagaat aaaatcgtcg gcgacgcgac tttgcgcgtg aacgagcgcg
    23701 gcaatggcgt taccgtttgg aacgcgcccg gcgcgcaggt cgtcggcaac gatatttcca
    23761 aagggcggga cggcattttt tccaatacca gcacgcacaa cacctataaa aacaaccgct
    23821 tcagcgattt gcgtttcgcc gtccactata tgtacaccaa cgacagcgaa atcagcggca
    23881 atatttccgt gggcaacaat atgggctatg tgctgatgtt ttccgagcgg ctcaaagtgt
    23941 ttgacaatat cgccgtcggc agccgcgacc aaggcatcat gctcaactat gtcaactatt
    24001 ccgatattca cgacaacatt atcaacaaag cgggcaagtg cgtttttgcc tacaatgcca
    24061 actacgataa actgtccgcc aatcattttg aaaactgcca aatcggcata cactttaccg
    24121 ccgccatcga aggcacgtca ctgcacgaca attcctttat caacaacgaa agccaggtca
    24181 aatacgtcag cacgcgcttt ctcgactgga gcgagggcgg acacggcaac tattggagcg
    24241 acaacagcgc gttcgatttg aacggcgacg gcttcggaga cagcgcgtac cgtcccaacg
    24301 gcatcatcga ccaaatcatc tggcgcgcac ccgtatcgcg cctcttgatg aacagtcccg
    24361 caatcagcat cgtcaaatgg gcgcaggcgc agtttcccgc cgttctgcct ggcggcgtgg
    24421 tggacagcaa accgctgatg aagccttatg cccccaaaat tcaaacccgt tatcaggcga
    24481 tgaaggacgg gctgctcaaa gaagccgaaa cgcggcagtt ggaatggggc agggcggaaa
    24541 acggttcttt gaactagtct gtttcagacg gcatccggat tcaaatgccg tctgaaaaca
    24601 caaaaggaaa aaccatgacc acacatcatg tcgaattgag gaatgtaacc aaacggttcg
    24661 gggcgcaaaa agcggtcaac caagttgatt tggttttgaa ggcaggagaa agcgtcgggc
    24721 ttgccggaca caacggcgcg ggcaagtcca ccattatgaa gctgatactc gggctgatta
    24781 ccccgaccga aggcgaagtg atgcttttgg gcgaacgtac cggtagcaaa gcgggggcgc
    24841 ggcttcgcag ccaaatcggc tacctgcccg aaaccgttgc gctgccccct tcgctgaccg
    24901 gcatcgaaac gctggatttt tatgccaaac ttaaaaaaca gccgctcacg cagaaccggg
    24961 ggctgcttga gcgtgtcggt atttcacagg cggcacaccg ccgcgtcggc acttattcta
    25021 aagggatgcg ccaacgcctt gccttggcac aagccctgct gggcgagccc aaagtcctgc
    25081 tgtttgacga accgacaacc ggcctcgacc ctgcatcacg acaaatgttt tacgaagtcg
    25141 tgcgcgaact caacgggcgc ggcgcgaccg tattgctcag cacccacgcc cttgccgagt
    25201 tggacggaca cgccgaccgc attatcgtgg attaaattta aaccagtacg gcgttacctc
    25261 gccttgccgt actatttgta ctgtctgcgg cttcgttgcc ttgtcctgat ttttgttaat
    25321 ccactatatg cgggtatggc gggtttgagc ggacaaatca gcctgaccgt ccccgttttg
    25381 ctgaccgctc aggttttatg ggttatcatt ccgcttgttt tggcagccgg aatttttaga
    25441 aagcgacaaa tatgaaaaaa accctgttgg caattgttgc cgtttccgcc ttaagtgcct
    25501 gccggcaggc ggaagaggga ccgccgcctt taccccggca gattagcgac cgttcggtcg
    25561 gacactattg cagtatgaac ctgaccgaac acaacggccc caaagcccag attttcttga
    25621 acggcaaacc cgatcagccc gtttggttct ccaccatcaa gcagatgttc ggctatacca
    25681 agctgcccga agagcctaaa ggcatccgcg tgatttacgt taccgatatg ggcaatgtta
    25741 ccgattggac gaatcccaat gccgacacgg agtggatgga tgcgaaaaaa gccttttacg
    25801 tcatcgacag cggctttatc ggcggtatgg gtgcggaaga cgcgctgccg ttcggcaaca
    25861 aggaacaggc tgaaaaattt gcaaaggata aaggcggtaa ggttgtcggt ttcgacgata
    25921 tgcctgatac ctatattttc aaataatatt gaaaaaaccg gccgaaactt taaaaacgag
    25981 tttcggtcgg tttttctttt cttgttcggt atagtgtcgg caggaaagaa ccttcacatc
    26041 ccgccgtaat tcggcccgct cgcgccttcg gggcaaatcc aagtgatgtt ttgcgtcggg
    26101 tctttgatgt cgcaggtttt gcagtgcacg cagtttgccg cgttgatttg caggcgcgga
    26161 ttgccgtttt cttcaacaat ttcgtacacg ccggccggac aatagcgcgt ttcgggcgag
    26221 gcgtattctt tgtagttcac gtctatcatc gtttgcggat tgttcagcac caaatggtcg
    26281 ggctggtttt cttcgtgcgc gagattggca aggaagacgc tgctcaagcg gtcgaaggtc
    26341 aacacgccgt cgggtttcgg ataatcaatc ggtttgcacg cggcggcttt tttgagctgc
    26401 tcgttgtctt tgccgtaatg tttcaaggtc cacggggctt tgcctctgaa aatcatctgg
    26461 tcgatgccgg tatagattga gccgaggtaa acgccccatt tgaatgacgg acggacattg
    26521 cgcgcggcgt aaagctctcg atacagccag ctttgttcaa aacgttgctg ataatccgcc
    26581 gcttctttgc cgctgtcgaa accctccgct tcttcaaggt gttccaacaa ggggaacacg
    26641 gcttcggcgg cgatcatagc ggatttcatc gcggtatgga tgcctttgat gcgcggcata
    26701 ttgaggaaac ctgccgcatc gccgattaaa acgccgcctt tgaacgagag cttcggcaaa
    26761 ctttgcaaac cgccttcaat cagcgaacgc gcgccgtaag caatgcggcg gccgccttca
    26821 aaggttttgc ggatttcggg atgggttttg aaacgttgga actcttcaaa cggcgacaga
    26881 taaggatttt gatagtccaa accgaccacg aagccgacgg cgactttgtt gtcgtcgaaa
    26941 tggtaaacaa acgcgccgcc gtaggttttg ctgtccagcg gccagcctgc gctgtgcacc
    27001 accaaaccgg gctgatgctg ttcggacggc acttcccaaa cttctttcat gcccaagccg
    27061 taagtttgcg gctggctgtt ttggtcgagt ttgaagcgtt cgatgatttg tttggaaagc
    27121 gaacctcggc agccctcggc aaacagggtt tgccgtgccc aaagctccat gccgggctgg
    27181 aatgaatcgg tcggctcgcc gtctttgccc acgcccatat tgccggtcgc aatgcctttg
    27241 accgaaccgt cttcgtgata cagtacttcg gcagcggcaa agccaggata gatttccacg
    27301 cccatatttt ccgcctgctc cgccaaccag cgcacgactt cgcccaagct gacgatgtag
    27361 ttgccgtgat tgtcgaaatt cggggtaata ggcagattga acgccttttt cttagtcagg
    27421 aacaatactt tgtcctgcgt taccgtacgc gtcagcggcg cgcctttttc tttccaatcg
    27481 ggaatcagct cgttcagcgc aatcggatcg ataaccgcgc ccgccagcga atgcgcgccc
    27541 gtctcagaac ctttctccac cacgcaaacg ctgatttcgc gcccgttttg ttcggcaagc
    27601 tgcttgagtt tgatggcggc agacaaaccc gacgggcctg cgccgacaat cacgacatcg
    27661 tattgcatac tgtcgcgggt gatggattct gtcatggcgg ttcctgtgta tttattattg
    27721 aattgcaaat ccgtaattat acaacgggaa catatagtta ccaaatacaa caaaggtcgt
    27781 ctgaaaacca tattttcggt tttcagacga cctttgtcga aatttcaata agcacgccac
    27841 cattttacct gtccgaccgc aaactccgtc tgacgtttcg gactgcgtgt gaaaaacgcc
    27901 ttatccccgc cggcatccct cc
//
LOCUS       DAXISH010000021        27850 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.021, whole genome shotgun sequence.
ACCESSION   DAXISH010000021 DAXISH010000000
VERSION     DAXISH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 27850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27850
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.021"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..344
                     /locus_tag="ACFOV4_000926"
     CDS             <1..344
                     /locus_tag="ACFOV4_000926"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFC7618960.1"
                     /translation="NYISNQQLTNFTIKDEFKDALDINFAFYYFFIIAEQSKKLINTS
                     SLPIISMKELKKLKIPIPPLPEQEKIAAILDKFDILTHSISEGLPHEIALRRKQYEYY
                     REQLLAFPKAT"
     gene            423..3521
                     /locus_tag="ACFOV4_000927"
     CDS             423..3521
                     /locus_tag="ACFOV4_000927"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HFC7618961.1"
                     /translation="MNLETKPIAETPNFIVLDQYEKIEQSGSYQSENRLEAELIADLQ
                     NQGYEYRKDLNSQSRLLENLRAQLQRLNDVAFSDGEWARFLTEYLDRPSENITDKTRK
                     IHDDHIYDFAFDDGRLKNIYLLDKKNLARNHVQLINQFEQTGTHANRYDVTVLVNGLP
                     LVQIELKKRGVAVREAFNQVHRYSKESFNSENSLFKFLQIFVISNGTDTRYFANTTKR
                     DKNSFDFTMNWARSDNHPIKDLKDFTATFLQKSVLLSVLLHYSVFDANDTLLIMRPYQ
                     IAAAERILWKINSSAQAKNWSKPESGGYVWHTTGSGKTLTSFKAARLATESAFIDKVF
                     FVVDRKDLDYQTMKEYQRFSTDSVNGSESTAGLKRNLEKDDNKIIVTTIQKLNNLMKS
                     EDNLPVYHQRVVFIFDECHRSQFGEAQKNLKKKFKKFCQFGFTGTPIFPENALGAETT
                     AGVFGRELHSYVITDAIRDEKVLKFKVDYNDVRPQFKAVEAEQDEKKLSAAENRQALL
                     HPERIREITQYILNQFRQKTHRLNAGGKGFNAMFAVSSVDAAKCYYEAFKTQQAGSLH
                     PLKVATIFSFAANEEQNAVGEIVDETFEPEAMDSSAKEFLQAAINDYNACFKTNFGTD
                     SKAFQNYYRDLAKRVKNQEIDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLMQAFSR
                     TNRIYDATKTFGNIVCFRDLEQATIDAITLFGDKNTKNVVLEKSYEEYMNGYIDSQTG
                     EARRGYLDVAKELRERFPDPDEIETEKDKKDFAKLFGEYLRAENVLQNYDEFAALREL
                     QNVDAADEDAMKAFQEKYYLSDEDVQEMRQVPMPSERAVQDYRSAYNDIRDWLSRQKA
                     GEQKEQSKIDWDDVVFEVDLLKSQEINLDYILQLVFEHHKKIKGKAELVEEIRRIIRA
                     SIGHRAKEGLIVDFINDTDLDKVPDVPAILETFYTYAQEVMRHEAAGLIAAEDLNETA
                     AKRYLTGSLKRGYASENGTELTETLPKMSPLNPQYLTKKQSVFQKIAAFVEKFAGIGT
                     DI"
     gene            complement(3561..5852)
                     /gene="clpA"
                     /locus_tag="ACFOV4_000928"
     CDS             complement(3561..5852)
                     /gene="clpA"
                     /locus_tag="ACFOV4_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0043335 - protein unfolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HFC7618962.1"
                     /translation="MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNV
                     LKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVETRPTLGFQRVMQRAMVHTQSAGK
                     AAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYSSDGMD
                     DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLV
                     GEAGVGKTALAEGLAHQIVNGGIPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVL
                     KQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGSLRCIGATTYDEYRT
                     IFDKDHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSSR
                     YINERFLPDKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDD
                     KQVLQFLGRDLKNMVYGQENAIDALVAAVKMSRSGLGLPDKPIGSFLFSGPTGVGKTE
                     AAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNKQPHCVL
                     LLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGF
                     TAKRERGDEMQAINKLFTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKK
                     VEAEFTPALHKYLAEKGFDPQMGARPMHRLIQEKIRKPLADELLFGKLTDGGFVRIDW
                     DAAKEEAVLKFKKSKVKIKTASA"
     gene            complement(5854..6156)
                     /gene="clpS"
                     /locus_tag="ACFOV4_000929"
     CDS             complement(5854..6156)
                     /gene="clpS"
                     /locus_tag="ACFOV4_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HFC7618963.1"
                     /translation="MTAQHQSDTLLRRLNTLPPKRYGVFLLNDDYTTMEFVVEILTEI
                     FMLGQEQAVAVMLLVHHEGKGLCGTYTRDIAQTKQQQVMQRAKAEGHPLQCIVEEI"
     gene            6399..6602
                     /locus_tag="ACFOV4_000930"
     CDS             6399..6602
                     /locus_tag="ACFOV4_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFC7618964.1"
                     /translation="MATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMEGFKTLKE
                     GQRVSFDVTTGPKGKQAANIQAA"
     gene            complement(6696..6887)
                     /locus_tag="ACFOV4_000931"
     CDS             complement(6696..6887)
                     /locus_tag="ACFOV4_000931"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618965.1"
                     /translation="MPSEDEGSTFCPVPARLPFYAAPPFADNIAHFFISTDFPLSVKI
                     LSHLSTTGYTQVQDKACGD"
     gene            complement(6899..8230)
                     /gene="pmbA"
                     /locus_tag="ACFOV4_000932"
     CDS             complement(6899..8230)
                     /gene="pmbA"
                     /locus_tag="ACFOV4_000932"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HFC7618966.1"
                     /translation="MLFNHTASELLDLCRRTLDLAKAAGATAAEADFSESIGQSVSVR
                     LGEIEQIEFQQDKSLDITVYVGKRKGRAGTADFSEQALRDTVRAAADIARHTAEDGCA
                     GLADACLMAKHIGDPDLYHEWDLDTEAAVGLAKQCEQAALNEDERIENSEGAAVQTGH
                     YQYVYGNTHGFAAHRQGTHHSISCSVVAADENGMQRDYWYDSACRHPDMDSPETIGQT
                     AARRTLRRLGSRSIPTGSYPVLFDTTVSGGLIGHLVGALSGGALYRQSSFLIDSIGKK
                     VLPDFLNLREEPHIPRSFRSSYFDAEGVATAPRFVIQNGIVEGYFLSSYSARKLGMQT
                     TGNAGGAHNLYLNHTHETQSDLLKEMGTGLLVTELMGQGANTITGDYSRGAAGFWVEN
                     GVIAYPVHEITVAGRLQDMYRDIVGVADDALRRSSNKIGSILIAGMTVAGS"
     gene            8384..8896
                     /gene="yjgA"
                     /locus_tag="ACFOV4_000933"
     CDS             8384..8896
                     /gene="yjgA"
                     /locus_tag="ACFOV4_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="HFC7618967.1"
                     /translation="MFEQEDEWVSKTQMKKQMNGLQDLGMELTKLSSDTLKKIGLDED
                     LYEAIVTYKKITSNGALKRQAQFIGRLMRDTDPAPIEAFLAKLRGDDAAHNAFLQRVE
                     RTRMELLADDGALTQFMSDFPNADAGKLRTLIRNTKKEQEQNKPPKNFRALFQELKTV
                     MESQGGTGEA"
     gene            8943..9680
                     /locus_tag="ACFOV4_000934"
     CDS             8943..9680
                     /locus_tag="ACFOV4_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618968.1"
                     /translation="MLFRKTTAAVLAAALMLNGCTAMMWGMNDPFSQTTAYKHVDKDQ
                     IRAFGVVAKDNAQLEKGSLVMMGGKYWFVVNPEDSAKLTGILKAGLDKPFQIVEDTPS
                     YARHQALPVKLESPGSQNFSTEGLCLRYDTDKPADIAKLKQLGFEAVELDNRTIYTRC
                     VSAKGKYYATPQKLNADYHFEQSVPADIYYTVTEKHTDKSKLFANILYTPPPLFDTGC
                     GGRGTGFACGGSGCGRGCRPQMNSNAV"
     gene            9732..11432
                     /gene="recJ"
                     /locus_tag="ACFOV4_000935"
     CDS             9732..11432
                     /gene="recJ"
                     /locus_tag="ACFOV4_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFC7618969.1"
                     /translation="MSAKIQTRSVNTDVFNHLLTAGADPLIAQLCASRGVQSPAELDD
                     KLASLLPYQSLTNCEAAARRLADAVGRKEKILIVADYDADGATACSVGMSGLAAMGAK
                     VDFLVPNRFEHGYGLTPELAEIAAEQGVDLLITVDNGIASIAGVARAQALGLDVIVTD
                     HHLPAETVPDCIIVNPNQKGCGFPSKSLAGVGVIFYVLMALRAELRRRNYFSDGIKEP
                     NLGELLDLVALGTVADVVPLDHNNRILVSQGLKRMRSGKMRPGIRALFEVARRDWRKA
                     QPFDMGFALGPRINAAGRLDDMSVGIACLLARDDTEAQELAAQLNNLNIERREIEQSM
                     LQDALNAFPETLPSGQMTLVAYRDDFHQGVVGIVASRLKDRFYRPTIVFAPADNGEVR
                     GSGRSIPNLHLRDALDLVSKRHPDLILKFGGHAMAAGLSILEHNIPAFQTAFEEAVRE
                     MVCEDDLSQTFITDGSLPARDITLEQAQNLAKHVWGQGFAPPSFTDEFHVVRQQPLGA
                     EGKHKKAWLQKDGCEFEAMFWRCSEDIPEYIRTVYRPVANEWRNNLELQLYIDYWEAA
                     "
     gene            11787..13148
                     /locus_tag="ACFOV4_000936"
     CDS             11787..13148
                     /locus_tag="ACFOV4_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HFC7618970.1"
                     /translation="MLKKWLNKMLPSSRSSKEAESKTVIPAERHNIRAEMLSFAAENV
                     IRRLKEAGFQAYVVGGAIRDLLLGIEPKDFDVATDAMPEQVHKLFRRSRIVGRRFQIV
                     HVMNGAEIIEVTTFRGGAKVHQNAHGRIMKDNTYGSIEEDAMRRDFTCNALYYDPEKE
                     EILDFHNGIADVAARRLVMIGDAAERYQEDPVRILRAIRLSGKLGFELSEETTAPIAE
                     SICRLKHEPVARLFDEIMKLLFSGHARECLKRLNGFDIPDDIHPLLNALRVSDGIAGK
                     MTVLALKNTDERLRADKSVSVGFVLAALMWPELERHWKSNLQQGLKPAPALSDAINTM
                     RETVERGWGVPQRFSATMREIWMFQPQFENRKGARPHKLFAQARFRAAYDFLLLRAET
                     GNADRALAEWWTAFQTASTEQRSEMTKNEAAARHEKNEGQAKKRRRRRRKPKPKVVGT
                     DWE"
     gene            13321..13644
                     /locus_tag="ACFOV4_000937"
     CDS             13321..13644
                     /locus_tag="ACFOV4_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618971.1"
                     /translation="MKKCILGILTACAAMPAFADRIGDLEARLAQLEHRVAVLESGSN
                     TVKIDLFGSNSTMYVCSVTPFQKTFEASDRNEGVARQKVRQACNRETSAMFCEDEAIR
                     CRKFD"
     gene            complement(13755..14708)
                     /locus_tag="ACFOV4_000938"
     CDS             complement(13755..14708)
                     /locus_tag="ACFOV4_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFC7618972.1"
                     /translation="MTHTVHLHLEETDNLALQRLCGSFDNNLDLLAKALDIHISRRFE
                     HFTFNGAFAHAGKRALLKLLETAQTRDLNDGDIRLAAVEAQTEDAGHQEKNHDHAYYF
                     RTKRGSIGGRTPRQNGYIRALLNHDIVFGLGPAGTGKTYLAVAAAVDAMEKHQVERII
                     LVRPAVEAGEKLGFLPGDLTQKVDPYLRPLYDALYDLMGFDRVTKLIEKGLIEIAPLA
                     YMRGRTLNGAYIILDEAQNTTPEQMKMFLTRIGFGAKAVITGDTSQIDLPKNIKSGLK
                     DAREKLHGVEGLYFHTFTGEDVVRHPLVQKIVEAYESAEHD"
     gene            complement(14847..16092)
                     /locus_tag="ACFOV4_000939"
                     /pseudo
     CDS             complement(14847..16092)
                     /locus_tag="ACFOV4_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003678130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            16238..16942
                     /locus_tag="ACFOV4_000940"
     CDS             16238..16942
                     /locus_tag="ACFOV4_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248833.1"
                     /note="The SIMPL domain is named for its presence in mouse
                     protein SIMPL (signalling molecule that associates with
                     mouse pelle-like kinase). Bacterial member BP26, from
                     Brucella, was shown to assemble into a channel-like
                     structure, while YggE from E. coli has been associated
                     with resistance to oxidative stress; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HFC7618973.1"
                     /translation="MLRSILAASLLAVSFPAAAEALNYNIVEFSESAGVEAVQDTMSA
                     RLQVAAEGRDKNAVNAEFVKKFNKFIRKSKNGSFKTELVSRSAMPRYQYTNGRRIQTG
                     WEERAEFKVEGRDFDELNRFIADVQADAALEYTDFHVSRERRNEVIDQVSKDAILRFK
                     ARADKLSGILGTSGYKIVKLNLGHIGSHIAGEGAAQAKMLRAMPMAASYGVEGTDSAA
                     PGVEEISISVNGTVQF"
     gene            complement(17006..17572)
                     /gene="dcd"
                     /locus_tag="ACFOV4_000941"
     CDS             complement(17006..17572)
                     /gene="dcd"
                     /locus_tag="ACFOV4_000941"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003823864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006229 - dUTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HFC7618974.1"
                     /translation="MSIKSDKWIRRMSEEFGMIDPFEPNQIKEADGKRIISYGTSSYG
                     YDIRCANEFKIFTNINSTIVDPKNFDPKNFVTVEDDCCIIPPNSFALARTVEYFRIPR
                     NVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGVAQVLFF
                     ESDEICETSYKDRNGKYMGQTGVTLPKA"
     gene            complement(17638..18054)
                     /locus_tag="ACFOV4_000942"
     CDS             complement(17638..18054)
                     /locus_tag="ACFOV4_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HFC7618975.1"
                     /translation="MLKHLAFLLPAMMFALPAASAVLTSYQEPGCTYDGGVGKDRLPS
                     GKGIWRCRDGRGYTGSFKNGKFDGQGVYTVAANREIFIEPFNSDSTKFRNMVLSGTFK
                     KGLAHGRFTVSQNGETLFIMKCENGMIKEVKLPKNK"
     gene            complement(18106..19005)
                     /locus_tag="ACFOV4_000943"
     CDS             complement(18106..19005)
                     /locus_tag="ACFOV4_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HFC7618976.1"
                     /translation="MWFKQISFYPLNKEKLPEADVLADKLAEAEFTHCQGLEWFSEGF
                     AAPVSFSPELVFPADFTLRVALKKEEKVLPAGVIRDILEEKVAEIQNNEARNVGRKEK
                     QELKEQITDDLLPRAFTRSSRTEAVFNTRHGYLLVNNAASAKAENILTKLREALGGLE
                     ASLPNTKQSPSSLMTGWLLQGHCEGGFELDSDCELKGTGDIVPVVKVSKQDLTADEVV
                     QHVKNGKTVTQLGLVWREQIAFILTQDFTLKRIQYLDVLQEEAESNGDDAASLAFASQ
                     ILMAESVSTMLEELVSYLGGWQD"
     gene            complement(19036..20493)
                     /gene="der"
                     /locus_tag="ACFOV4_000944"
     CDS             complement(19036..20493)
                     /gene="der"
                     /locus_tag="ACFOV4_000944"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003745900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFC7618977.1"
                     /translation="MKPTIALVGRPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGH
                     GKVGSKPYLVIDTGGFEPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKI
                     IADRLRQSPRPVYLAVNKGEGGNRAVLAAEFYELALGDPYVISGAHGDGVYYLIEDIL
                     ETFPEPEKEEEEAKHPVFAVIGRPNVGKSTLVNAILGEERVIAFDMAGTTRDSIHIDF
                     EREGKPFTIIDTAGVRRRGKVDEAVEKFSVIKAMQAVEAANVAVLVLDAQQDIADQDA
                     TIAGFALEAGRALVVAVNKWDGISEERREQVKRDINRKLYFLDFAKFHFISALKERGI
                     DGLFDSIQAAYNAAMIKMPTPKITRVLQSAIERQQPPRAGLVRPKMRYAHQGGMNPPV
                     IVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQYNVSENPYENAEDKPKKKPLR
                     RVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK"
     gene            complement(20647..21276)
                     /locus_tag="ACFOV4_000945"
     CDS             complement(20647..21276)
                     /locus_tag="ACFOV4_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfgM family protein"
                     /protein_id="HFC7618978.1"
                     /translation="MAAHLEEQQELDNFKYFWKTTGKWLFALLILAALGYLGYTVYQN
                     RAASQNQEAAAVLANIVEKAQNKAPQSEINAELTKLQQSYPHSISAAQATLMAAATEF
                     DAQRYDVAEGHLKWVLSNQKDSLIQALAAQRLGVVLLQQKKYDAALAALDTPVEADFS
                     PLLMETKGDVYAAQGKSQEALKNYGQALEKMPQDSVGRELVQMKLDSLK"
     gene            complement(21277..22572)
                     /gene="hisS"
                     /locus_tag="ACFOV4_000946"
     CDS             complement(21277..22572)
                     /gene="hisS"
                     /locus_tag="ACFOV4_000946"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFC7618979.1"
                     /translation="MAQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVNRWTRAYG
                     YQQIRTPIVEQTGLFVRSIGEETDVVGKEMYTFSDSNDSLSLSLRPEGTASCLRAVVE
                     HNLLYNSPQKLWYMGPMFRRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLW
                     EKLGIREYLTLEINSLGNREERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDT
                     KNPDLQEICNAAPRLVDYLGEASQNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTV
                     FEWTTDKLGAQATVCGGGRYDGLIEELGGKPAPSIGFAMGIERLLLLVSEYGSLEVNA
                     APDVYAMHQGERADLQVMKYAQALRAQGFNVMQHSGYQSLKAQMKKADNSGARFALIV
                     AQDELANGTVTLKDMNGAHGQQTVAAEDLTHTLQQWKNA"
     gene            complement(22698..23354)
                     /locus_tag="ACFOV4_000947"
     CDS             complement(22698..23354)
                     /locus_tag="ACFOV4_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFC7618980.1"
                     /translation="MMKFKYVFLLACVVVSLSYRLNAAPMFNDNPVVYGKIKVQSWKA
                     RRDFNIVKQDLDFSCGAASVATLLNNFYGQTLTEEEVLKKLDKEQMRASFEDMRRIMP
                     DLGFEAKGYALSFEQLAQLKIPVIVYLKYRKDDHFSVLRGIDGNTVLLADPSLGHVSM
                     SRAQFLDAWQTREGNLAGKILAVVPKKAETISNKLFFTHHPKRQTEFAVRQIRQARAE
                     "
     gene            complement(23412..23602)
                     /locus_tag="ACFOV4_000948"
                     /pseudo
     CDS             complement(23412..23602)
                     /locus_tag="ACFOV4_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24357..24515)
                     /locus_tag="ACFOV4_000949"
     CDS             complement(24357..24515)
                     /locus_tag="ACFOV4_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618981.1"
                     /translation="MKTFEKTWSAQYRDMEISVRNFWNLERTGAEVYINGRRVYHNEA
                     EMASASLR"
     gene            complement(24672..25091)
                     /locus_tag="ACFOV4_000950"
     CDS             complement(24672..25091)
                     /locus_tag="ACFOV4_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618982.1"
                     /translation="MSFGYLIATSQPCELLTKSRGETFSLIMDKMDLWIYFRFCEGNI
                     YTIRKNETESCLTERGGKWLKHIYEFNRGSFIFSYVLLKKRESEENFAEIVLKSIKNN
                     KILTVKVRSGLHFDLRNIYRIEMYSGLNLNQYGVASP"
     gene            complement(25149..25514)
                     /locus_tag="ACFOV4_000951"
     CDS             complement(25149..25514)
                     /locus_tag="ACFOV4_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618983.1"
                     /translation="MEKPLLTPPFFLFEDVSLDIFQGLSELEKKIEPQDLMDDVYRAF
                     DSVGNILNFRIVEKEQKGFWVSTKIKTVVFDSADMSSDDLFLKCLQSSYKAYFETEPA
                     GLDKRQLMKTLIQKCGFSC"
     gene            complement(25496..26041)
                     /locus_tag="ACFOV4_000952"
     CDS             complement(25496..26041)
                     /locus_tag="ACFOV4_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618984.1"
                     /translation="MKKQITAAVMMLSMIAPAMANSMDNQIFENQVFHTRADAPMQLA
                     ELSQKEMKETERAFLPLAILGGAAIGMWTQHGFSYATTGRPASVRDVAIAGGLGAIPG
                     GVGAAGKVVSFAKYGREIKIGNNMRIAPFGNRTGHPIGKFPHYHRRVTDNTGKTLPGQ
                     GIGRHRPWESKSTDRSWKNRF"
     gene            complement(26204..26475)
                     /locus_tag="ACFOV4_000953"
                     /pseudo
     CDS             complement(26204..26475)
                     /locus_tag="ACFOV4_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220648.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(27351..27599)
                     /locus_tag="ACFOV4_000954"
     CDS             complement(27351..27599)
                     /locus_tag="ACFOV4_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7618985.1"
                     /translation="MNIKNEIVALISKKIDGGQYSSLENFALSVLREKIIKNTVSSDE
                     KLLIINDFLSGFLEFDPETGKPVGETLKIEQMIDFFLV"
BASE COUNT         6874 a         6766 c         7112 g         7098 t
ORIGIN      
        1 ttaattatat tagtaaccaa caactgacca attttacaat taaagatgaa tttaaggatg
       61 ctttagatat aaatttcgct ttctattatt ttttcattat tgcggagcag agcaaaaaac
      121 ttattaatac ttcaagttta cctattatta gcatgaaaga attaaagaaa ttaaaaatcc
      181 ccatcccacc actccccgaa caggaaaaaa ttgccgccat cctagacaaa ttcgatatcc
      241 tgacccactc tatcagcgaa ggcctgccgc acgaaatcgc cctgcgccgc aaacaatacg
      301 aatattaccg cgaacagctg cttgccttcc ctaaggctac ctgaaaaagc agcctgcaca
      361 ttttcaggca gcccaatccg aacatcaaac cgtttaaaac ccgatactgc aaaggacgac
      421 ccatgaacct cgaaaccaaa cccatcgccg aaacgccgaa tttcatcgtg ctcgaccaat
      481 atgaaaaaat cgaacagtcg ggcagctacc aatcggaaaa ccggttggaa gcggagttaa
      541 tcgccgattt gcagaatcag ggttacgaat accgcaagga tttgaacagc caaagcaggc
      601 tgctggaaaa cctgcgcgcg cagttgcagc ggctgaacga tgtggcgttt tcagacggcg
      661 aatgggcgcg gtttttgacg gaatatctgg acagaccgtc tgaaaatatt accgataaaa
      721 cccgcaaaat ccacgacgac catatttacg atttcgcttt tgatgacggc cgtctgaaaa
      781 acatttatct gctggacaag aaaaaccttg cccgcaacca tgtgcagctt atcaaccagt
      841 ttgagcagac gggcacgcat gcaaaccgtt atgacgttac cgtgttggta aacggtctgc
      901 cgctggtgca gattgaattg aaaaagcgcg gtgtggcggt gcgcgaagca ttcaatcagg
      961 tgcaccgtta cagcaaagag agcttcaaca gcgaaaattc gctgttcaaa ttcctgcaaa
     1021 tcttcgtgat ttccaacggc acggacacgc gctatttcgc caacaccacc aagcgcgaca
     1081 aaaacagctt cgatttcacg atgaattggg cgcggtcgga caatcatccg attaaggatt
     1141 tgaaagactt taccgccacg ttcctgcaaa aaagcgtatt gctgagcgtt ttgctgcatt
     1201 acagcgtgtt cgatgcgaat gatacgctgc tgattatgcg gccgtaccag attgccgccg
     1261 ccgaacgcat tctgtggaaa atcaacagct cggcgcaggc gaagaattgg agcaagccgg
     1321 agagcggcgg ctatgtttgg cacaccacgg gcagcggcaa aacgctgacc agctttaagg
     1381 cggcgcgtct ggcgacggaa tcggcattta tcgacaaggt tttcttcgtg gtggacagga
     1441 aggatttgga ctatcagacg atgaaggaat accaacgttt ttcgaccgac agcgtgaacg
     1501 gttcggaaag cacggcgggc ttgaaacgca atttggaaaa agacgacaac aaaatcatcg
     1561 ttaccaccat ccaaaagctg aacaacctga tgaaaagtga agataatctg ccggtttacc
     1621 atcagcgggt tgtctttatt ttcgacgaat gccaccgctc gcaattcggc gaagcgcaaa
     1681 aaaacctgaa aaagaaattt aaaaaattct gccagttcgg ttttaccggc acgccgattt
     1741 ttcccgaaaa cgctttgggc gcggaaacca cggcgggcgt gttcgggcgg gagctgcatt
     1801 cttatgtgat taccgatgcc atccgcgatg aaaaagtatt gaaattcaaa gtggattaca
     1861 acgatgtgcg cccgcagttc aaagccgtgg aagcggaaca ggacgagaag aaactgagtg
     1921 ccgccgaaaa ccgccaagcc ctgctgcacc ccgaacgcat ccgcgaaatc acgcaatata
     1981 tcctgaacca gttcaggcag aaaacgcacc ggctgaatgc gggcggcaaa ggctttaacg
     2041 cgatgtttgc cgtcagcagc gtggatgcgg cgaagtgcta ttacgaagcg ttcaaaacgc
     2101 aacaggcagg cagcctgcac ccgttgaaag tggccactat tttttccttt gctgccaacg
     2161 aagagcagaa cgccgtcggt gaaattgtcg atgaaacctt tgaaccggaa gcgatggaca
     2221 gcagcgcgaa agaatttttg caggctgcca tcaacgatta caacgcctgt ttcaaaacca
     2281 atttcggcac ggacagcaaa gcctttcaga actactaccg cgatttggca aaacgggtga
     2341 aaaatcagga aatagatttg ctgattgtgg tcggcatgtt tttgacgggt tttgacgcgc
     2401 cgacgctgaa cacgctgttt gtcgataaaa acctgcgcta tcacggcctg atgcaggcgt
     2461 tttctcgcac caaccgcatt tacgatgcca ccaaaacctt cggcaatatt gtctgcttcc
     2521 gcgatttgga gcaggcgacc attgatgcga ttaccctgtt cggcgacaaa aacaccaaaa
     2581 acgtggtgct ggaaaaaagc tacgaagaat acatgaacgg ctatatcgac agccagaccg
     2641 gcgaagcgcg gcgcggctat ttggatgtgg caaaagaatt gcgcgaacgt ttccccgatc
     2701 ccgacgaaat cgaaacggaa aaagacaaaa aagattttgc caaactcttc ggcgaatacc
     2761 tgcgggcgga aaacgtattg cagaactacg atgaatttgc cgcgctgcgc gagttgcaga
     2821 atgtggatgc ggcggacgaa gatgcgatga aggcgtttca ggaaaaatac tacctgagcg
     2881 atgaagacgt gcaggaaatg cggcaagtgc cgatgccgtc tgaaagggcg gtgcaggact
     2941 accgttccgc ctacaacgac atccgagact ggctgagccg ccaaaaagca ggcgaacaga
     3001 aagaacagtc aaaaatcgat tgggacgatg tggtttttga ggtagatttg ctcaaatcac
     3061 aggaaatcaa tctggattac atcctgcaac tggttttcga gcatcacaaa aaaatcaaag
     3121 gaaaagcgga gctggtggaa gaaatccgcc gcatcatccg cgccagcatc ggccaccgcg
     3181 ccaaagaggg tctgattgtg gattttatca acgatacgga tttggataaa gtccccgacg
     3241 ttcccgccat actggaaacc ttttacacct acgcgcaaga ggtaatgcgg cacgaagcgg
     3301 caggattgat tgccgccgaa gacctgaacg aaaccgccgc caaacgctat ttgaccggct
     3361 cgctcaaacg cggctatgcc agcgaaaacg gtacggaact gaccgaaacc ctgccgaaaa
     3421 tgagtccgct caacccgcaa tatctgacga agaaacaaag tgtttttcaa aagattgcgg
     3481 cgtttgtgga gaagtttgcc ggaataggga ccgatatttg acaaaatgcc gtctgaacct
     3541 ttcagacggc atttttgatt ttatgcggag gcggttttta ttttgacctt gcttttctta
     3601 aacttcaaca cggcttcttc ttttgccgca tcccagtcta tccgcacgaa gccgccgtcg
     3661 gtaagtttgc cgaacaggag ttcgtcggcg agcggtttgc ggattttttc ctgaatcagg
     3721 cggtgcatcg ggcgcgcgcc catttgcggg tcaaaacctt tttccgccag atatttgtgc
     3781 aatgccggcg tgaattcggc ttcgactttt ttgtcgagga gctggtgttc gagctggagc
     3841 aggaatttgt ccacgacttt gacgatgatg ggttcggaca agggtgcaaa cgggataatc
     3901 gcgtccaagc ggttgcggaa ctcgggcgtg aagagcttgt tgattgcctg catttcgtcg
     3961 ccgcgttcgc gcttggcggt aaagccgagg ctggggcggc tgaggctttc cgcgcccgcg
     4021 ttggtggtca taatcagaat gacgttgcgg aaatcggcac tcttgccgtt gttgtcggtc
     4081 agtttgcctg cgtccataac ttgcaggagg acgttgaaaa tgtcggggtg ggctttttcg
     4141 atttcgtcca agagcaacac gcaatgcggc tgtttgttga cggcttcggt caaaaggccg
     4201 ccttgttcaa agccgacgta gcccggcggc gcgccgatga gtcgtgatac ggcgtggcgt
     4261 tccatgtatt cggacatatc aaagcgttgc agcggtacgc ccatcgagta ggcaagctgt
     4321 ttggcggctt cggttttgcc cacgccggtc gggccggaga agaggaagct gcctatcggt
     4381 ttgtcgggca gtcccaagcc cgaacgcgac attttgacgg cggcaaccag cgcgtcgatg
     4441 gcattttcct gaccgtaaac catgtttttc aaatcgcggc cgaggaattg cagcacctgt
     4501 ttgtcgtcgt gcgacacggt tttttctgga atccgcgcga ctttggcgat gacggtttcg
     4561 atttgcgctt tgccgatgac ttttttctgt ttggatttgg gcagaatccg ttgcgccgcg
     4621 cctgcttcgt ccatcacgtc gatggctttg tcgggcagga aacgctcgtt gatgtagcgt
     4681 gaggagagtt cggcggcggc ttcgagtgcg ccttgcgtat agcggacttg gtggaaggct
     4741 tcaaacatcg gcttcaagcc gcgcaggatt tgtacggttt cggaaacggt gggttcgacc
     4801 acgtcgattt tttggaagcg gcggcttaag gcatggtctt tgtcgaaaat ggtgcggtat
     4861 tcgtcgtagg tggttgcgcc gatgcagcgc agcgaacctt ttgccagcgc gggtttgagc
     4921 aggttggacg cgtccatggt gccgccgctg gtgctgcctg cgccgatgat ggtgtggatt
     4981 tcgtcgataa acaaaatggc gtgcgggatt ttttcgagct gtttcaagac ggatttgacc
     5041 cgcgcttcaa agtcgccacg gtatttcgtg cccgccaaca gcgagcccat atccagcgcg
     5101 tacacttcgg catctttaag cgcgtctgga atgccgccgt tgacgatttg atgtgccaaa
     5161 ccttccgcca gcgcggtttt gcccacgcct gcttcgccga ccaaaagcgg attgtttttg
     5221 cggcggcggc ataggatttg caccagccgt tccatttcgt gtttgcgacc aatcaaaggg
     5281 tcgatacggc cggctttgac ttcggcgttg aggttgacgg tgtacgccga taaagggttt
     5341 ttgcccggtt tggtgcggtt ctcattatcg tcgtccatgc cgtctgaaga atagttgcca
     5401 tcgtcttcat cttcatcggg agagccgtgg gcaatacagc gcaaaacttc aaaacgcgta
     5461 accgattgca gcttgaggaa atagacggtg tggctgtcgg tttcgctcat cagcgcgact
     5521 aaaacgtcca acggttcgac tgcggctttt ccggcagact gggtatgcac catcgcccgt
     5581 tgcatcacgc gttggaagcc gagcgtgggc cgggtttcga ccgtgtctaa aaggtgttcg
     5641 ggaatcaggg gggtgttttc ggcaacgctg gcggcgagct gttcggacac cactttcaaa
     5701 tccgcgccgc agagttttaa gacgttcggc acggaggcat cttcttcgat gagtaccaaa
     5761 agcagatgct cgaggctgat aaattcataa tgagccttac gcgcctcgcg gtaaagctgc
     5821 tgcaaaatct gttccaattc gggtgcaagc atattaaatc tcctcgacaa tacattgcag
     5881 cggatgccct tcggcttttg cccgctgcat gacttgttgt tgtttggttt gggcaatatc
     5941 gcgcgtgtaa gtgccgcaca ggcctttgcc ttcgtgatga accaagagca ttaccgctac
     6001 cgcctgttct tgtccgagca taaagatttc ggtcaggatt tcgacgacaa attccatcgt
     6061 ggtgtaatcg tcgttcaata ggaaaacgcc gtaacgtttc ggcggcaggg tgttcaggcg
     6121 gcgcaagagc gtgtcggatt ggtgttgcgc ggtcatagtg tgtcccattt gaaagccgcg
     6181 ttcagacggc atttttgttg tattttcggt acttttgcct attttcccac ttttttgaaa
     6241 acatagcttg acgttttgtc ttaacaaatg taaaaagacg gttaagcagg attgggcatc
     6301 cgccgagtat atcaagctgg aaggaacgcc agacggctcg gtttgccgta tgccttgttt
     6361 tgctgatttt gttaattttt gagtatagga agtttctaat ggcaaccggt atcgtaaaat
     6421 ggtttaacga cgctaaaggt tttggtttca tcactcctga tgaaggcggc gaagatttgt
     6481 tcgctcactt ctcagcaatc aatatggaag gtttcaaaac cctgaaagaa ggccaacgcg
     6541 tctctttcga cgtaaccacc ggccctaaag gcaaacaggc cgccaacatt caggctgctt
     6601 aattcctgat gtacggtcaa atgtatattt gaaaacggcg ggacaggcaa tgtcccgccg
     6661 tttttgtctg ccgttttgcc ggcggcggaa aaaccctaat ccccgcacgc cttatcctga
     6721 acttgtgtgt accctgttgt ggacaagtgg cttagtattt tgacggataa gggaaaatca
     6781 gtgctgatga aaaaatgtgc aatgttgtcg gcaaaaggcg gtgcggcata aaacggcaaa
     6841 cgggcaggca cggggcaaaa cgtgctgcct tcgtcttcag acggcatcgg cagggcgttc
     6901 agcttccggc aaccgtcatc cccgcaatca gaatcgagcc gattttgttg gacgaacgcc
     6961 gcaaagcgtc atccgccacg ccgacaatgt cgcggtacat atcctgcaag cgtccggcta
     7021 cggtaatctc gtggacgggg taggcaatca cgccgttttc cacccaaaaa cccgccgcgc
     7081 cgcgcgagta gtcaccggta atggtgttcg cgccctgtcc catcagttcg gttaccaaca
     7141 atcccgtccc catttctttc agcaggtcgg attgcgtttc gtgcgtatgg ttcaaataca
     7201 ggttgtgcgc gccgccggcg ttgcccgtgg tctgcatacc gagtttgcgc gcgctgtaac
     7261 tgctgaggaa atagccttcg acaatgccgt tttgaatcac gaagcgcggc gcggtggcaa
     7321 cgccttccgc atcaaaatag ctgctgcgga aagagcgggg gatgtgcggt tcttcgcgca
     7381 ggttgaggaa atcgggcagg acttttttgc cgatgctgtc gatcaggaaa ctgctttggc
     7441 ggtagagcgc accgccggag agtgcgccga cgaggtgtcc gataagaccg cccgaaacgg
     7501 tggtatcgaa gaggacgggg tagctgcctg tcgggatgct gcggctgccg agtcggcgca
     7561 aagtgcggcg ggcggcggtt tgaccgatgg tttcggggct gtccatatcc ggatggcggc
     7621 aggcggaatc gtaccagtag tcgcgctgca tgccgttttc gtcggcggca acgacgctgc
     7681 aggaaatgct gtggtgcgtg ccttgccggt gtgcggcaaa accgtgggtg ttgccgtaaa
     7741 cgtattggta atggccggtt tgcaccgccg cgccttcgga gttttcgatg cgctcatcct
     7801 cgttcagggc ggcttgttcg cattgttttg ccaagccgac ggcggcttcc gtatccaaat
     7861 cccattcgtg gtaaaggtcg gggtcgccga tgtgttttgc catcagacag gcatcggcaa
     7921 gtccggcgca accgtcttcg gcggtgtggc gggcgatgtc ggcggcggcg cggacggtgt
     7981 cgcgcagggc ttgttcggag aaatcggcgg tgccagcgcg gcctttgcgt ttgccgacgt
     8041 aaacggtaat gtccagcgac ttgtcctgct ggaactcgat ttgttcgatt tcgcccagcc
     8101 gcacgctgac gctttgtccg atggattcgc tgaaatcggc ttcggcggcg gtcgcgcccg
     8161 ctgcttttgc caagtcgagc gtgcggcggc agaggtcgag aagttcggaa gcggtgtggt
     8221 tgaacagcat agaaatcttt cttggtggag cgttgcggca ttttaaccgt ttcgggcggc
     8281 aggggcaaaa gcgtccgttt gcagggcgga cggtgcaaaa tgccgtctga acgcggaatc
     8341 attctgttaa aatgcgcccg tcggataaaa tttgagaatg aagatgtttg aacaagaaga
     8401 cgaatgggtc agcaaaaccc aaatgaaaaa gcagatgaac ggtttgcagg atttgggtat
     8461 ggagctgacc aagctctcaa gcgacacgtt gaaaaaaatc ggcttggacg aagatttgta
     8521 cgaagccatc gttacctata aaaaaatcac atccaacggc gcgctcaagc ggcaggcgca
     8581 atttatcggc agactgatgc gcgataccga tcccgcgccc atcgaggcat ttcttgccaa
     8641 gctgcgcggc gacgatgcgg cgcacaacgc ctttttgcaa cgtgtggagc ggacgcggat
     8701 ggagctgctg gcggacgacg gcgcgctgac gcagtttatg tccgattttc caaacgccga
     8761 tgcgggcaag ctgaggacgc tcatccgcaa taccaaaaaa gaacaggaac agaacaaacc
     8821 gccgaaaaat ttccgcgccc tgtttcaaga gttgaaaacc gttatggaaa gccaaggcgg
     8881 aacaggggaa gcctaggcat attttcagac ggcatccgcc gtcattctga ttggaagata
     8941 aaatgttgtt ccgtaaaacg accgccgccg ttttggcggc agccttgatg ttgaacggct
     9001 gtacggcaat gatgtggggc atgaacgacc cgttcagcca aacgaccgcc tataaacacg
     9061 ttgacaagga tcaaatccgc gccttcggtg tggttgccaa agacaatgcc caattggaaa
     9121 agggcagtct ggtgatgatg ggcgggaaat actggttcgt cgtcaatccc gaagattcgg
     9181 cgaagctgac gggcattttg aaggcagggc tggacaaacc cttccaaata gttgaggata
     9241 ccccgagcta tgctcgccac caagccctgc cggtcaaact cgaatcgcct ggcagccaga
     9301 atttcagtac cgaaggcctt tgcctgcgct acgataccga caagcctgcc gacatcgcca
     9361 agctgaaaca gctcgggttt gaagcggtcg aacttgacaa tcggactatt tacacgcgct
     9421 gcgtatccgc caaaggcaaa tactacgcca cgccgcaaaa actgaacgcc gattatcatt
     9481 ttgagcaaag tgtgcctgcc gatatttatt acacggttac tgaaaaacat accgacaaat
     9541 ccaagctgtt tgcaaatatc ttatatacgc ccccccccct ttttgatact ggatgcggcg
     9601 ggcgcggtac tggctttgcc tgcggcggct ctgggtgcgg tcgtggatgc cgcccgcaaa
     9661 tgaacagcaa tgccgtctga aaagctttca gacggcattt cagcctcatc atatcttgaa
     9721 aaaacctcgt catgtcagcc aaaatccaaa cccgatccgt caataccgac gtttttaatc
     9781 atttgctcac cgccggtgcc gatcctttaa tcgcccagct ttgtgcttcg cgcggtgtgc
     9841 aaagtcctgc cgaattggac gacaaactcg cttccctcct gccttatcaa tcgttgacga
     9901 attgcgaagc cgccgcccgc cgtttggcgg atgcggttgg gcgcaaggaa aaaatcctga
     9961 ttgttgccga ctatgatgcc gacggtgcga cggcgtgttc cgtcggtatg agcggtttgg
    10021 cggcgatggg ggcgaaagtg gatttccttg tgcccaaccg ctttgagcac ggctacggct
    10081 taacgcccga gctggctgaa atcgcggcag agcaaggtgt ggatttgctg attacggttg
    10141 ataacggtat cgccagcatc gcaggcgtgg cgcgcgcgca ggctctgggt ttggatgtca
    10201 tcgttaccga ccaccatctg cctgccgaga ccgtgcccga ctgcatcatc gtcaatccga
    10261 accaaaaagg ctgcggtttt ccaagcaaaa gcttggcggg cgtgggcgtg attttttatg
    10321 tattgatggc tttgcgtgcc gaattgcgcc gccgcaatta tttttcagac ggcatcaaag
    10381 agccgaatct gggcgaactt ttggatttgg tcgcactcgg cacggttgcc gatgtcgtcc
    10441 ctctcgacca caacaaccgc atcctcgtgt cgcaaggttt gaaacggatg cgctccggca
    10501 aaatgcgccc cggtatccgc gccttgtttg aagtggcgcg gcgcgattgg cgcaaggcgc
    10561 agccgtttga tatgggtttt gcgttgggcc cgcgcatcaa cgccgccgga cggctggacg
    10621 atatgtcggt cggtattgcc tgcctgttgg cgcgagatga taccgaggcg caggaactgg
    10681 cggcgcagtt aaacaacctc aatatcgaac gtcgcgaaat cgagcagtct atgctgcaag
    10741 acgcgctgaa tgcttttcct gaaaccctgc cttcaggtca gatgactttg gtggcgtatc
    10801 gcgacgactt ccatcaaggc gtggtcggca tcgttgccag ccgcctcaaa gaccgttttt
    10861 atcgtccgac catcgtgttt gcgcctgccg acaacggtga agtgcgcggt tcggggcgtt
    10921 ccattcccaa tcttcacttg cgcgatgctt tggacttggt gtccaaacgc catcccgatt
    10981 tgattttgaa attcggcgga cacgcgatgg cggcgggctt gagcatactc gaacacaaca
    11041 ttcccgcgtt tcagacggcc tttgaagaag ccgtgcgcga aatggtgtgc gaagacgatt
    11101 tgtcgcaaac cttcatcacc gacggcagcc tgcctgcacg cgacattacg ctggaacagg
    11161 cgcaaaacct tgctaaacac gtttgggggc agggcttcgc gccgccgagt tttaccgacg
    11221 agttccacgt cgtccgccag cagcctttgg gcgcggaagg caaacacaaa aaagcgtggc
    11281 tgcaaaaaga cggctgcgaa tttgaagcaa tgttctggcg gtgcagcgaa gacattcccg
    11341 aatacatccg cacggtgtac cgccccgttg ccaacgaatg gcgcaacaac ctcgaattgc
    11401 agctttatat cgactactgg gaagcggcgt agaggcggcg gaacgccgtt tgaatgtgat
    11461 ttctgttcct tcatttgcct gtttgtacga cgggaatgtt cccaatcgga aaagaaagta
    11521 aagggcgtta atttttgtta atcatccctt cttagggacg caatatataa ggtgcatcaa
    11581 atttcagact ctgccacaaa agcagggtct gatttttttg gagggcaatc tgttataatg
    11641 acgcgttgcc gccgcgaggg cggcgtgatt cggacggcgt agtttctacg ccttttgttt
    11701 atggttacgg catcttgcaa acctgcgccc gatgccgtct gaacacggtt gcccgtggag
    11761 atgccgctct tcgggtcaga atatttatgc tgaaaaaatg gttgaataag atgctgcctt
    11821 ccagtcggag cagtaaagaa gcggaaagta aaacggtcat tcctgccgaa agacacaaca
    11881 tccgtgccga aatgttgagc tttgccgccg aaaacgtcat acgccgcctg aaagaggcag
    11941 ggtttcaggc ttatgtggtc ggcggcgcga tcagggacct gctgctcggc atcgaaccca
    12001 aggatttcga tgtcgcaacc gatgccatgc ccgaacaggt gcacaaactc ttccgccgca
    12061 gccgcatcgt cggcaggcgt tttcaaatcg tccatgtgat gaacggtgcg gagattatcg
    12121 aagtaacgac gtttcgcggc ggtgcgaaag ttcatcagaa cgcgcacggc aggattatga
    12181 aggacaacac ctacggcagc atcgaagaag atgcgatgcg gcgcgatttt acctgcaatg
    12241 ccttgtatta cgatccggaa aaagaagaga ttttggattt ccacaacggg attgccgatg
    12301 ttgccgcccg caggctggtt atgattggcg atgccgccga acgctatcag gaagaccctg
    12361 tcaggatttt gcgcgccatc cgcctgtcgg gcaaattggg ctttgagctg tcggaagaaa
    12421 ccaccgcacc gattgccgaa tcgatatgcc gtctgaagca cgaaccggta gcgaggctgt
    12481 ttgacgaaat catgaaactg ctgttttcag ggcacgcgcg cgagtgtctg aaacgtttga
    12541 acggatttga cataccggac gacatccatc cgctgctcaa tgccttgcgc gtttcagacg
    12601 gcatcgccgg aaaaatgacg gtgcttgccc tgaaaaatac cgatgagcgg ctgcgtgccg
    12661 acaaatcggt ttcggtcggt tttgtattgg cggctctgat gtggcccgag ttggaacgcc
    12721 attggaaaag caatctgcaa cagggtttga aacccgcgcc cgccctgtcc gatgcaatca
    12781 atacgatgcg cgaaaccgtc gaacgcggtt ggggcgtgcc gcaacgcttt tccgccacga
    12841 tgcgcgaaat ttggatgttc cagccgcagt ttgaaaaccg caaaggcgca cgtccgcaca
    12901 aactgtttgc acaggcgcgt ttccgtgccg cctatgattt cctgctcttg cgcgccgaaa
    12961 ccggcaatgc ggaccgcgcc cttgccgagt ggtggacggc gtttcagacg gcatcgacgg
    13021 aacagcggtc ggagatgacc aaaaacgaag ccgccgcccg acacgaaaaa aacgaaggac
    13081 aggcgaaaaa acgccgccgt cgcaggcgca aacccaagcc gaaggttgtg ggaacggatt
    13141 gggaataagg gtcaacagac aaggagcaat gaagtttcaa cacatgggat gaagcataaa
    13201 gtgccgttct atgtattatc ctgatttgta aggggattca tccccgtaaa taaagtctaa
    13261 ccctgcctct cggaaaaagg atgtccgggt gggcagggtt caagaaacaa ggaaaaattg
    13321 atgaaaaaat gtattttggg cattttgacc gcgtgtgccg ccatgcctgc atttgccgac
    13381 agaatcggcg atttggaagc acgtctggcg cagttggaac accgtgtcgc cgtattggaa
    13441 agcggcagca ataccgtcaa aatcgacctt ttcggttcaa attccaccat gtatgtatgc
    13501 agcgttacgc cttttcagaa gacgtttgag gcaagcgatc ggaatgaagg cgtggcgcgg
    13561 cagaaagtgc gtcaggcgtg caaccgcgaa acttcggcaa tgttttgcga agatgaggca
    13621 atccgatgca gaaaattcga ttgatgtatc ggttggacgg ataaagaaac ggatacggat
    13681 acggagcttg gcttccgtat ctgtttttct ctgcccgatt ttccatgcat cgggtttcag
    13741 acggcattgg aatgtcagtc gtgttctgcc gattcgtagg cttcgacgat tttttgcacc
    13801 aaaggatgcc ggacaacgtc ttcgccggta aaggtgtgga aatacagccc ttccacgccg
    13861 tgcagtttct cacgcgcatc ttttaatccc gatttgatgt ttttgggcag gtcgatttgg
    13921 ctggtgtcgc cggtaatgac ggctttcgcg ccgaagccga tgcgggtcag gaacattttc
    13981 atttgttcgg gcgtggtgtt ttgcgcttcg tcgaggatga tgtatgcgcc gttgagcgtc
    14041 ctgccgcgca tataggcgag cggggcgatt tcaatcaggc ctttttcaat cagcttggtg
    14101 acacggtcaa agcccatcag gtcatagagg gcatcataaa gcggacgaag gtagggatcg
    14161 actttctggg tcaggtcacc gggcagaaaa cccagtttct cgccggcttc gacggcaggc
    14221 cgcactaaaa tgatgcgttc gacttggtgt ttttccatcg catcgacggc ggcggcgacg
    14281 gcgagatagg ttttgcccgt acctgccggc ccgagaccga atacgatgtc gtggttgagt
    14341 agggcgcgga tatagccgtt ctgccgtggc gttctgccgc cgatgctgcc gcgtttggta
    14401 cggaaataat aggcgtggtc atggtttttt tcttgatgac cggcatcttc ggtttgggct
    14461 tcgacggcgg caagcctgat gtcgccgtcg tttaggtcgc gcgtctgcgc cgtttccaag
    14521 agtttgagca gtgcgcgttt gccggcgtgt gcaaatgcgc cgttgaaagt gaaatgttca
    14581 aaacggcggc tgatgtggat atcgagtgct ttagcaagta aatcaaggtt gttgtcaaaa
    14641 gaaccgcaca gacgctgcaa cgccaagttg tcggtttctt ctaaatgcag gtggacggta
    14701 tgtgtcatat gaaggtccga atagttggat attgtgtgat tttaatctat agtggattag
    14761 atttaaacca gtacggcgtt gcctcgcctt agctcaaaga gaacgattct ctaaggtgct
    14821 gaagcaccaa gtgaatcggt tccgtactat ttgtactgtc tgcggcttcg tcgccttgtc
    14881 ctgatttttg ttaatccact atatttcacc ggtattttct taccgtattc tgcgattgcc
    14941 tgtcggaaaa tgccgatcaa cctgcctata acggcatttt cgccaaattc gttcagacag
    15001 ttttccctaa gtcgggcagg ttcgaaatca gagtggtgtt catacatttt gatgagtgcg
    15061 tcggcaaggg catcgtcgtc gtcaacagga accaaatatc cgttgccgtc tgaaacaata
    15121 gattccgcac cgccgcagcg tgttgcaatg acgggcaatc cttgggacag tgcttcgata
    15181 tagaccacgc cgaaggtttc ggtgcggctg gcaaggacaa atgcgtcgct gttcttcatc
    15241 aaatccaaga ctgcttcggg ttgcagtgcg cccaaaaatg taacggcatg ggtaatgccc
    15301 aagtctgccg cctgctgttt cagccgctgt tcttcctgtc cgctgccgcc gatgtttaga
    15361 cgcagttgcg ggcattgtgc caacgcccgg gcaaaggcag tgagcaggac atcgtgtcct
    15421 ttgagacggc gaaggtgcga gacggtgcag aacacgaaat gcggtttgtt gtttttttct
    15481 ctttgttcaa acggtcggtt gaatattccg cccagtatgt tggggaggta ctgccattcg
    15541 cagccgtatt tgtgttgcag gacgtgtgcg aaatggcggc tgatggcgag acgtgcggcg
    15601 gcgtgcgccg ccgcattttt cataggctgc cattggtggg gacggatcag accgcgcgta
    15661 atggtgctgc tgtgtttcgt gacgacatag gggatgccgt atttttggga aattttttgg
    15721 gcgagtatgc cggcatagtt catgcggtgg gcgtgaatca ggtcgggcag cccgttttcg
    15781 cggatgtagt gtttgaaggc tttcaaaccc acgcgcaccc agcggatgcg gtcgatgtcg
    15841 atgaacggaa agcgggggaa gaaatacatg ccgtgccatg catagatgtc caaaccgctt
    15901 tgccgatatt ttgcaaaacc gtaaggtcgg tcaggatgct tgctgtttct ttccgcaagt
    15961 agcggaacat cggtgcaagc acggcggttt tgatgccttt cctctgcaat gccagtgcct
    16021 gattttgaaa aaaatcccgt ccacatcctg ttcggattgc ggataccatg aggggatgac
    16081 gaggacgtgc aagggtttgg gcatagtggg attccgtatc ggaaaggcgg ttattataag
    16141 acagacgcag accgaatatt taaattgttg ccttacgcta acgcaattta gcgcgccgat
    16201 atgctagatt ggcggtttta taagtaagga tacggatatg ctgcgttcta ttttggcggc
    16261 ttccctattg gcggtatctt ttccggcagc ggctgaagca ttgaattaca atattgtcga
    16321 attttccgaa tcggccggtg tcgaggcggt tcaggataca atgtccgcgc gtttacaggt
    16381 ggcggcggaa ggacgggaca aaaatgccgt caatgccgag tttgttaaaa aattcaacaa
    16441 gttcatcaga aaatcgaaaa atggtagctt taaaaccgaa ttggtatcgc gcagtgcgat
    16501 gccgcgctat caatatacca acggcagacg cattcaaaca ggttgggagg agcgtgcgga
    16561 atttaaggtc gaagggaggg attttgatga gttaaaccgt tttattgccg atgttcaggc
    16621 agatgccgca ttggaatata cggatttcca tgtgtcgcgc gaacgccgaa acgaggtcat
    16681 cgatcaggtc agtaaagatg ctattttgcg tttcaaggcg cgtgcagaca agttgtcggg
    16741 catattgggt acgtccggtt ataaaatcgt caaattaaat ttgggacaca tcggcagcca
    16801 tatcgcgggt gaaggagctg ctcaggcaaa aatgcttcgt gccatgccga tggcggcaag
    16861 ttacggcgtg gagggtacgg attccgccgc gccgggtgtg gaggaaatca gcatcagcgt
    16921 caatgggacg gttcagttct gatttgaggt gaacggcaaa tgccgtctga aacccgacga
    16981 taagggttca gacggcattt atatttcagg ctttgggcag ggttacgccg gtttgtccca
    17041 tgtatttgcc gttgcggtct ttgtatgagg tttcgcagat ttcgtcgctc tcgaagaaga
    17101 ggacttgcgc cacgccttcg ccggcgtaga ttttggcggg caggggggtg gtgttggaaa
    17161 attcgagggt aacgtagcct tcccattccg gttcgaacgg ggtaacgttg acgatgatgc
    17221 cgcagcgggc gtaggtggat ttgcccaagc agacggtcag gacgttgcgc gggatgcgga
    17281 aatattcgac cgtgcgcgcc agtgcgaagg aattaggcgg gatgatgcag cagtcgtctt
    17341 caacggtaac gaagtttttt gggtcgaagt ttttgggatc gacgatggtg ctgttgatgt
    17401 tggtgaagat tttaaattcg ttggcgcagc ggatgtcgta gccgtagctg gacgtaccgt
    17461 aggagatgat gcgtttgccg tcggcttctt tgatttggtt cggctcgaaa gggtcgatca
    17521 tgccgaattc ttcgctcatg cggcgtatcc atttgtcgga cttgatgctc ataatgtttt
    17581 ccttgtttct tgcagtgttc ggacaaagca ttgggggatg ccgtctgaaa acggggctta
    17641 tttgtttttg ggcagcttca cttctttaat catgccgttt tcgcatttca taatgaagag
    17701 ggtttcgccg ttttgcgaga cggtaaatct gccgtgtgcc aagccttttt tgaacgtgcc
    17761 cgagagtacc atgttgcgga atttggtact gtcggaattg aacggttcga taaatatttc
    17821 gcggttggcg gcaacggtat aaacgccttg tccgtcgaat ttgccatttt taaacgaacc
    17881 ggtataaccg cgcccgtccc ggcaacgcca tatgcctttg cctgaaggaa gcctgtcttt
    17941 tccgactccg ccgtcgtagg tgcagccggg ttcttgatag gaagtcagaa cggcggacgc
    18001 ggcggggagg gcgaacatca tggcgggcag taggaatgcg agatgtttaa gcataagggt
    18061 tattccattg gattttggct gacggtataa aagccgtctg aaaaatcaat cttgccagcc
    18121 gcccaaatag gaaaccagct cttccaacat ggtgctgacg gattcagcca tcaggatttg
    18181 cgaggcgaag gcaaggctgg cggcatcgtc gccgttgctt tcggcttctt cctgcaatac
    18241 gtcgaggtat tggatgcgct tgagtgtgaa gtcttgagtg aggataaagg cgatttgttc
    18301 gcgccaaacc aaaccgagct gggttacggt tttaccgttt ttgacgtgtt gaaccacttc
    18361 gtcggcggtt aaatcttgtt tggatacttt gacgacggga acaatatcgc ccgtaccttt
    18421 gagttcgcaa tcgctgtcca attcaaaacc gccttcgcaa tgcccttgca acagccagcc
    18481 ggtcatcaga gaagagggcg attgtttggt attcggcagc gaggcttcca aaccgcccaa
    18541 agcttcgcgc agcttggtca ggatgttttc tgctttggcg gaagccgcgt tattgacgag
    18601 caggtagccg tggcgggtgt taaacaccgc ttctgtacgg ctgctgcggg taaacgctcg
    18661 gggcagcagg tcgtctgtaa tttgctcttt aagctcttgt ttttctttgc gaccgacatt
    18721 gcgggcttca ttgttttgga tttccgccac cttctcttcc aaaatatcgc ggatgacgcc
    18781 ggcaggcagg actttttctt cttttttcag ggcgacgcgc aaggtaaagt cggcagggaa
    18841 aacgagttcg ggagagaacg aaaccggtgc ggcaaagcct tcgctgaacc actctaagcc
    18901 ttggcaatgg gtaaattcag cttcagcaag tttgtcggca agtacgtctg cctcaggcag
    18961 cttttctttg ttgagcggat aaaaactaat ctgcttgaac cacataatgt ttcctattgt
    19021 ttgaaatgtc gggaattatt tgctgaattg ttttttcaca ctgactttgg ttttcttctt
    19081 gaagcggttt ttctcttctt tgcggccttc gcgtttctca atacggttgc tcaggctgac
    19141 gcggcgcagc ggttttttct tcggtttgtc ttccgcattt tcatacgggt tttccgaaac
    19201 attgtattga attctgagcg gcgtgccttg cagattgaag gctttgcgga acgtttgggt
    19261 cagatagcgc gtatagctgt cggaaatcgc gtgcagcgaa ttgccgtgta ccacaattac
    19321 gggagggttc atgccgcctt ggtgggcata acgcattttc ggacgcacca agccggcacg
    19381 cggcggttgc tgacgctcga tcgcgctttg taatacgcgc gtgattttcg gcgtcggcat
    19441 cttaatcatc gccgcgttgt aggcagcctg aatgctgtca aacaaaccgt ctataccgcg
    19501 ctctttcaat gcggaaataa agtggaactt ggcaaaatcg aggaaataca gtttgcggtt
    19561 gatatcgcgt ttcacttgct cgcgacgttc ttcgctgatg ccgtcccatt tattgaccgc
    19621 caccaccaaa gcacggcctg cctccaaagc gaaacctgca atcgtcgcat cttggtcggc
    19681 gatgtcctgc tgcgcgtcca ataccaaaac agcgacgttt gccgcttcaa ccgcctgcat
    19741 cgctttgata acggagaatt tttccactgc ttcatccact ttgccgcgac ggcgcacacc
    19801 tgcggtatcg atgatggtaa acggtttgcc ttcgcgctcg aaatcgatat ggatactgtc
    19861 gcgcgtcgta cctgccatat cgaaggcgat gacgcgctct tcgccgagaa tggcgtttac
    19921 caaggttgat ttaccgacat ttggacgacc gataacggca aaaacaggat gtttcgcctc
    19981 ttcctcttct ttttcaggct cagggaaggt ttccaaaata tcttcaatca gataatacac
    20041 gccgtcaccg tgcgcacctg aaataacata agggtcgccc aaagcaagtt cgtagaactc
    20101 ggcggcaagc acggctctat tgccgccttc tcctttattc acggccaaat aaacggggcg
    20161 cgggctttgg cgcaaacggt cggcaatgat tttatcttgc ggcgtcagac cggtacggcc
    20221 gtccaccaaa aacacaaccg catcggcttc atcgacagcc tgtaaggttt gttttgccat
    20281 ttcgtgcaaa atgccgctgt ccacaaccgg ctcgaaaccg ccggtatcga tgaccaaata
    20341 aggtttgctg ccgactttgc cgtgtccgta atggcggtcg cgggtcaggc cgggcaggtc
    20401 gtgtacgagt gcgtctttgg tgcgcgtcaa acggttgaat aaagtagatt tgccgacgtt
    20461 ggggcggccg acaagcgcga tggttggttt catgattgag tctttctgtg tcaagtgccg
    20521 ttcgggagaa ctgaacacga gcaggtgtcc gttggacacg gtaaataggt tcttcacggc
    20581 aagaggccat aaagagggag ggtaaaatgc cgtctgataa ataatggacg gcatttcaga
    20641 cggcatttat ttcagcgaat cgagtttcat ttgaaccaat tcacgaccga cagaatcttg
    20701 aggcattttt tctaaagcct gaccgtagtt ttttaaggct tcctggcttt ttccctgtgc
    20761 ggcatagaca tcgcctttgg tttccatcag caggggggag aagtccgctt caaccggcgt
    20821 gtcgagcgcg gcaagcgcgg catcgtattt tttttgttgc aacaacacaa cgcccagacg
    20881 ctgcgccgcc aacgcttgaa tcaggctgtc tttttggttg gacaacaccc atttcaaatg
    20941 gccttcggca acatcgtaac gctgcgcgtc aaattcggtt gccgccgcca tcagcgtggc
    21001 ttgggcggcg gaaatagaat gcgggtagct ttgttggagt ttggtcaatt cggcattaat
    21061 ttcgctttgc ggggctttgt tttgcgcctt ttccacgatg tttgccagca ccgccgccgc
    21121 ttcctgattt tgggaagccg cacggttttg gtaaaccgtg tatcccaagt agccgagtgc
    21181 tgccaaaatc agcagggcaa acagccattt gcccgtggtt ttccaaaaat atttaaagtt
    21241 gtctaactct tgttgttctt cgagatgggc tgccatttat gcgttcttcc attgttgtaa
    21301 agtatgggtt aaatcctcgg cggcgacagt ttgctgaccg tgtgcgccgt tcatgtcttt
    21361 gagcgtaacc gtaccgttcg ccagttcgtc ttgcgcgaca atcagggcaa agcgcgcacc
    21421 gctgttgtcg gcttttttca tttgcgcttt caggctttga tagccggaat gctgcattac
    21481 attgaaacct tgcgcgcgca aggcttgcgc gtatttcatc acctgcaagt ccgccctttc
    21541 gccttggtgc attgcataga catcaggcgc agcgttcact tccagcgagc cgtattcgct
    21601 caccaaaagc agcagccgtt cgatgcccat cgcaaagccg atggacggcg caggtttgcc
    21661 gccaagttcc tcaatcaaac catcgtaacg gccgccgccg cacacagttg cctgcgcgcc
    21721 gagtttgtcg gtcgtccact caaaaaccgt ctgattgtaa taatccaaac cgcgaaccaa
    21781 gcgcggattt tcaatatatt ggatacccaa accgtccaac atcgccttga agcgtgcata
    21841 gtggttttgc gaagcctcgc ccaaataatc caccaaacgc ggcgcggcgt tgcagatttc
    21901 ctgcaaatca gggtttttcg tatctaaaac acgcaaagga ttggttttca gacggcgttt
    21961 gctgtcttcg tccaatttat cttcatagcg tgtcaaatat tcaaccaacg ccgcacggtg
    22021 tgccgctcgc tcctcacggt tgcctaagct gttgatttcc aaagtcaggt attcgcggat
    22081 acccaatttt tcccacaagt cggcagacat cgcgatgatt tccgcatcga tatccggccc
    22141 ttcaaaaccc aaagcctcga taccgacctg atggaattga cgataacggc ctttttgcgg
    22201 acgctcgcgg cggaacatcg gccccatata ccacagcttt tgcgggctgt tgtacagaag
    22261 gttgtgttcg accaccgcac gcagacaaga agccgtacct tccggacgca ggctcaaact
    22321 caaagaatcg tttgaatcgg aaaaggtgta catttccttg ccgaccacat cggtttcctc
    22381 gccgatggag cggacaaaca aaccggtttg ctcgacaatc ggcgtacgga tttgctgata
    22441 gccgtaagcg cgcgtccagc ggtttaccgt atcctcaaac gcctgccaaa acgcagccgt
    22501 cagtttgaaa tctttttgct cgacaggcag aaggtcgttc atgcctttga cggattggat
    22561 tttttgtgcc atttcaagta agaatgctta aatcaaattg cgggcgatta tagcggattt
    22621 ttaagggttt gtgaggttgg gggtggtttg cggacgggta aaatgccgtc tgaaacagtt
    22681 ttcagacggc atttgactta ctctgcacgt gcttgcctga tttgtcggac tgcaaactct
    22741 gtctgccgct tgggatgatg tgtgaaaaac aatttatttg aaattgtctc ggcttttttc
    22801 ggcacgaccg ccaaaatctt acctgccaaa tttccctcac gggtttgcca agcatccaaa
    22861 aactgcgccc tgctcatcga aacatgaccc agcgacgggt cggcaagcaa aaccgtattg
    22921 ccgtctatac cgcgcaatac cgagaaatga tcatccttac ggtatttcag atacacgatg
    22981 acggggattt tcaactgcgc gagctgctcg aaagacaggg catagccttt cgcttcaaaa
    23041 cccaaatctg gcataatgcg ccgcatatcc tcaaacgacg cgcgcatctg ctccttatcc
    23101 agctttttca acacttcttc ttccgtcagc gtttgcccgt aaaaattgtt caaaagcgtc
    23161 gccaccgaag ccgccccgca ggaaaaatcc aaatcctgct ttacaatatt gaaatcccgc
    23221 cgcgctttcc aactctgcac tttgattttt ccgtaaacaa caggattatc gttaaacatc
    23281 ggtgcagcat tcagacgata agataaagaa acgacaacac acgccaacag aaaaacatat
    23341 ttgaacttca tcatattgtc cacataaagg gcagcctgaa aatctttcag gctgcccttg
    23401 tcaaattatt cctagctttc ggcttttttg gcaaaccaaa caatccgatt acccgcataa
    23461 tactttccat ttattgaaat ccgacaagcc gcgcccaaaa atgccatgca ctgtcgattt
    23521 ccgcagcaat ctttgtaccg ttttcttcaa attccaaata ttcacccaat aataaacttg
    23581 aaacagaacg cgtgggcagc aagtgcccac cctacgctta ttcaaataat ttgattaaat
    23641 aaagaataaa gaaaatgcat caggaacaaa attataatct gccacctgac tcacaccgct
    23701 tttaaagtaa ggggcatcaa aatcaaaacc gcaaaaaaaa taatttttgc attgattttt
    23761 aatagattta aaattcgaat atagtgtttc tccagattta aaaagtttat ctttatctat
    23821 atatttgatg ctttccctat ccaaaataaa tattcaaaca ttaaaaaatc attacatgac
    23881 caagccaaat cataaatttg attcaaatgg gtatcataaa gataaaaata ataaggtttg
    23941 ggaacaggta aaatatttaa tggaaaagga ggactaattt tcttaatatc tgatgactga
    24001 tatccatatc tttctatatt cttaaaaatt tcatctttct taagataaca agacattctg
    24061 aagataacaa gacattctga caatcacaac ctgttcatcg gatatattat ctatttgcat
    24121 ggcgcgtata acacgccatg cctgattaaa attagtctcc cttaccttag aatctattat
    24181 cttttccaaa gatgaaaatg ccccttatct tgaactctcc agttagaacc tggaagtttc
    24241 gtacctctta aatgtgtatt aatatttctt atagtttcat taaaatgcca cgcgctgccg
    24301 atttcaacgg taattttcgt accgctttct tcaaattcca ggtattcccc cattagctaa
    24361 cgcaaagaag cagacgccat ttcggcttcg ttatgataaa cccgccttcc gttgatatag
    24421 acttccgccc ctgtccgctc caaattccaa aaattccgta ctgaaatttc catatcccga
    24481 tattgtgcag accatgtttt ttcgaaggtt ttcataaaat ttcctatacc tgtccaatcg
    24541 gcacatatca attgcattat tatagtggat taacaaaaat caggacaagg caacgaagcc
    24601 gcagacagta caaatagtac ggaaccgatt cacttggtgc ttcagcacct tagagaatcg
    24661 ttctctttga gctaaggcga ggcaacgccg tactggttta aatttaatcc gctatacatc
    24721 tcaatacgat aaatatttct taagtcaaaa tgcaagcctg accgtacctt aactgtcaaa
    24781 attttattat tttttattga ttttaaaaca atttctgcaa aattctcttc gctttctctc
    24841 ttttttagaa gcacataaga aaaaataaaa cttccccgat taaattcata aatatgtttc
    24901 aaccatttgc ctcctctttc tgtaagacaa gattcagttt cattcttcct tattgtataa
    24961 atatttcctt cacaaaatct gaaataaatc cataaatcca tcttatccat aattaaagaa
    25021 aaagtttcac ctcgagattt tgtcaacaat tcgcaaggtt gcgatgttgc aatcaaatag
    25081 ccgaaagaca ttttttacct catacatggt cgaaatcagt ttctgttagt tcagaatcca
    25141 ttttttcgtc aacaactgaa tccgcatttt tgaattaacg ttttcatcag ctgccgttta
    25201 tctaaaccgg caggttcagt ttcaaaataa gccttatatg aagactgtaa gcatttcaga
    25261 aaaagatcat cagaagacat atctgccgaa tcaaatacaa ctgttttgat tttggtactt
    25321 acccaaaacc ctttttgctc tttttctact atacggaaat tcagaatatt tccaaccgaa
    25381 tcaaaagcac ggtaaacatc atccatcaaa tcctgcggct ctattttctt ttccaattcc
    25441 gacaatcctt gaaatatatc caaagacaca tcttcaaata gaaaaaaagg aggagttaga
    25501 agcggttttt ccatgatctg tccgtagatt ttgattccca agggcgatga cgaccaattc
    25561 cctgtccagg caaagtcttg cccgtattat ccgtaactcg acgatgataa tggggaaatt
    25621 ttccaatagg atgacctgtt ctattaccga aaggggctat ccgcatatta ttgccgattt
    25681 taatctcacg tccatattta gcaaaggaaa caacctttcc tgcggcgcct acaccaccag
    25741 gaattgcgcc taatccgcca gcaatagcaa catctctaac agaagctggt ctgcctgtcg
    25801 ttgcataact aaaaccatgc tgtgtccaca taccaatggc agcaccaccc aagatagcca
    25861 atggaagaaa cgccctctca gtctccttca tctccttttg agaaagttcc gccaactgca
    25921 tcggcgcatc tgcccgcgta tggaatactt ggttttcaaa tatctgattg tccatgctgt
    25981 ttgccattgc gggggcaatc atagacagca tcattacggc tgcggtaatt tgttttttca
    26041 taataactcc tttggattac aaggttggaa aatcaaagcc ctgcttagaa cgtatgttgc
    26101 acacccaatt tcaataggta aatcagattg caaatccagc aatttgaata ttgtcattgt
    26161 tccgtgcaaa agggattttt attgatgagt tgtgtactgg gtttcagctt ggctttttag
    26221 ataatctttt cacaagaaca tacatcaata ctgtccaaaa aaaagatttg ataaatatat
    26281 tgcaacatat tttattccac ctccatccga aacagaaacc aatatatttt taattaatac
    26341 atagctgatt attacattta ttattcctat aatatataag gatcttgcca aaattttttt
    26401 tgattttatt ttaggaatat ctcttatcca tgctaaaata cagcccaatg tcgaaaagaa
    26461 aataacagca aacactacct tacctcctct cacttccaac caaaccgata gcaggtttgg
    26521 ttggaagttg gtttatttat tatttaacgg cgaatgtcag tgttcttacc cgtagaacct
    26581 gcataaccat ttatgccacc agcaacagtc cccactgcta cacctcgcat accattaatc
    26641 agaattcttc ctattttttc gaatccacta tttcttccaa agatgcagca aacgcaggtt
    26701 aagcctagac ccaatctacg tttgctgccg catctgatcc ctattgtttc ttatccttac
    26761 atcttcctgc cttgtcaatc aaataaagac agaagactat acaaaaactg accgacatac
    26821 tgaaaatacc tatccccttc catgcaatct ccgcaccatt gacccaatag atcagactga
    26881 gaaacaacaa agccacagta taaatcaacg taaaaaatat tgcgtaaagc acaataaagg
    26941 gaacttttat ctcacggttg ttttttataa tacattcagc aacttgattt ccgaatatac
    27001 ctgataaaaa atatagtatt agatcatcca tttcgtttat cttctatgtt ttcccattgc
    27061 ggcgctagaa gactgattta atgctgcacc atgcaatata gtgaattaac aaaaaccagt
    27121 acggcgttgc ttcgccttag ctcaaagaga acgattctct aaggtgttga agcaccgagt
    27181 gaatcggttc cgtactatct gtactgtctg cggcttcgtc gccttgtcct gatttttgtt
    27241 aatctactag agtttaaaca actttatttt tgattttatc ccaagtataa acctgacaat
    27301 cgtatttaaa agccggatat aagcctagct tgttcactgg tatgtatgat ttagactaaa
    27361 aagaaatcaa tcatttgctc aattttaagc gtctccccga caggtttccc ggtctcagga
    27421 tcaaactcaa gaaaacctga taaaaaatca ttaataatca ataatttttc atcactggaa
    27481 acagtatttt ttataatttt ttcccttagt acggataaag caaaattttc taaagaacta
    27541 tattgccccc catcaatttt tttagaaatt aaagcaacta tttcattttt aatattcata
    27601 aattaccctt aaatgataaa gggagcgaag cccgcttaaa acgtataact gtatacccaa
    27661 tttcagcaag cacaggttga gttgccaagc ctaacagagc ctgaatgatt ggttataact
    27721 caaccttata tctacactta ccgaaaacct caaataactt aataaaaatc acacctaata
    27781 cttactgaaa cgataaacta cattttcttt aaataaggtt ttatctgtta tctcatttaa
    27841 agacaataaa
//
LOCUS       DAXISH010000022        26409 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.022, whole genome shotgun sequence.
ACCESSION   DAXISH010000022 DAXISH010000000
VERSION     DAXISH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 26409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26409
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.022"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(13..1308)
                     /locus_tag="ACFOV4_000955"
     CDS             complement(13..1308)
                     /locus_tag="ACFOV4_000955"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFC7618986.1"
                     /translation="MIRPDFQEYLPSYYFSSVNPHTVYPKLQCRLKTDTCIIGGGLSG
                     LCTALPLAEQGHETVVLEAARIGFGASGRSGGQVISDYACGMEEIEKQVGLEQAQWFW
                     QQSLQAVELVDERVRKHAIDCDWQRGYATVAIRSQHWEELQQWHEHAQKYYGATHYQL
                     WDNTELKQQLDSDMYQGAQFDPLSGHLHPLNYTLGVAGAAAEAGAQIFEQSPMTRIEP
                     HQNGWLVYTPEGSVECKNLVYAVNTYAGLNPIFQPLERKAIAVSTFIIATEPLGARAK
                     GLIRNNMAVCDNRHILDYYRLSADGRLLFGGKDNEFIDNPARMTELVRQDMLKVFPQL
                     DDVKIEYSWGGECDITANLVPHFGRLAANVFYAQGYSGHGMAITGIAGLAVAEAILGD
                     ECRLKPFERLRQPNIILQPFLRKLGSFLGSKYYQWKDSR"
     gene            complement(1434..2321)
                     /locus_tag="ACFOV4_000956"
     CDS             complement(1434..2321)
                     /locus_tag="ACFOV4_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFC7618987.1"
                     /translation="MQKSKLSWFLKLMLALSLAFLYIPLVVLVIYSFNESKLVTVWGG
                     FSTKWYGALLENDTILEAAWLSLRIAVVSSLAAVVLGTLAGYAMARIKRFRGSTLFAG
                     MISAPMVMPDVITGLSMLLLIIQVQIFLQGSEWLQHLYFDRGFFTIFLGHTTLCMAYI
                     TVVIRSRLVELDQSLEEAAMDLGARPLKIFFVITLPLIAPAIASGFLLGITLSLDDLV
                     ITSFLSGPGSSTLPQVIFSKIKLGLDPQMNVLATILIGIIGTLVIIVNYWMMRQATKR
                     DREAAEAYRQEKLAAEKAN"
     gene            complement(2321..3286)
                     /locus_tag="ACFOV4_000957"
     CDS             complement(2321..3286)
                     /locus_tag="ACFOV4_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFC7618988.1"
                     /translation="MNLNKLKNKLFRRPGQRAVIAVPYIWLLVLFLIPFAIVLKISFA
                     EQEIAIPPFTPLTTIDEDLGRLNIAVSYQNYADIFQNFWSTLNPFGDGENSNIYLMTY
                     WSSIKTALTTTVICLLVGYPTAYAISRANPSVRNGLLLAIMLPFWTSFLLRVYAWMGL
                     LGHNGIVNNLLIKMGIISEPLDLFYNAFSLNLVMVYAYLPFMILPLYTQLVKLDNRLL
                     EAASDLGAGPVKSFLTITLPLSKTGIIAGSMLVFVPAVGEFVIPELVGGSENLMIGKV
                     LWQAFFDQNNWPLASAVAVVMVALLVVPIALFQHYENRELEEGAK"
     gene            complement(3302..4426)
                     /gene="potA"
                     /locus_tag="ACFOV4_000958"
     CDS             complement(3302..4426)
                     /gene="potA"
                     /locus_tag="ACFOV4_000958"
                     /EC_number="7.6.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015417 - ABC-type polyamine transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter ATP-binding protein"
                     /protein_id="HFC7618989.1"
                     /translation="MTATTASSTKPYLQIQGLVKKFGDNYAVDNIDLDIYQHEIFALL
                     GSSGSGKSTLLRMLAGMESPNQGKIILDGQDITKLAPYDRPINMMFQSYALFPHMTVE
                     QNIAFGLKQDKMPKGEIAARVEEMLRLVQMTKFAKRKPHQLSGGQQQRIALARSLAKR
                     PKILLLDEPLGALDKKLRQQTQLELVNTLEQVGVTCIMVTHDQEEAMTMATRIAIMSD
                     GQLQQVGTPSDVYDYPNSRFTAEFIGETNIFDGVVIEDHADYAVIECEGLENHVRIDH
                     GLGGPSEQDLWVSIRPEDIDLYKEKPEYLGDYNWAKGTVKEIAYLGSFAIYHIKLSNG
                     RVVKSQVPAPYWYVRNITPPTWDETVYISWPENQPTPLFR"
     gene            complement(4622..4729)
                     /locus_tag="ACFOV4_000959"
                     /pseudo
     CDS             complement(4622..4729)
                     /locus_tag="ACFOV4_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(4808..5077)
                     /gene="rpsO"
                     /locus_tag="ACFOV4_000960"
     CDS             complement(4808..5077)
                     /gene="rpsO"
                     /locus_tag="ACFOV4_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019958878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFC7618990.1"
                     /translation="MALTVEQKAQIVKDFQRKEGDTGSSEVQVALLTFRINDLTPHFK
                     ANPKDHHSRRGLLKMVSQRRRLLAYLRRTQPDTYRALITRLGLRK"
     gene            complement(5300..6235)
                     /gene="secF"
                     /locus_tag="ACFOV4_000961"
     CDS             complement(5300..6235)
                     /gene="secF"
                     /locus_tag="ACFOV4_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HFC7618991.1"
                     /translation="MELFKIKRDIPFMSYGKLTTFISLVTFIAAVFFLVTRGLNFSVE
                     FTGGTVMEVQYQQGADVNKMRERLDTLKIGDVQVQALGTNKHIMIRLPNKEGVTSAQL
                     SNQVMDLLKKDSPDVTLRQVEFIGPQVGEELVSNGLMALGFVVIGIIIYLSMRFEWRF
                     AVSAIIANMHDIVIILGCFAFFQWEFSLTVLAGILAVLGYSVNESVVVFDRIRENFRK
                     PAMRGHAVPEVIDNAITATMSRTIITHGSTEAMVVSMLVFGGTALHGFSMALTIGIVF
                     GIYSSVLVASPLLLMFGLSRDNIGKEPKKKEEIVV"
     gene            complement(6239..8092)
                     /gene="secD"
                     /locus_tag="ACFOV4_000962"
     CDS             complement(6239..8092)
                     /gene="secD"
                     /locus_tag="ACFOV4_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HFC7618992.1"
                     /translation="MNRYPLWKYLLIVFTIAVAAVYSLPNLFGETPAVQVSTNRQAII
                     INEQTQSKVDAALKNAGIQTDGMFVVDNSLKVRFKDTETQLKARDVIENTLGEGYITA
                     LNLLADSPEWMAKIKANPMFLGLDLRGGVHFTMQVDMKAAMQKTFERYSGDIRRELRR
                     EKIRSGTVRQAGNSLTVPLQDAGDVQKALPQLRKLFPEATLNSDGSNIVLTLSEEAVN
                     KVRSDAVKQNITTLHNRVNELGVAEPVIQQSGADRIVVQLPGVQDTAKAKDIIGRTAT
                     LELRMVEDDPAKLREALEGNVPSGYELLSSGGDRPETLLISKQVELTGDNINDAQPSF
                     DQMGAPAVSLSLDSAGGSIFGELTAANVGKRMAMVLIDQGKSEVVTAPVIRTAITGGR
                     VEISGSMTTAEANDTSLLLRAGSLAAPMQIVEERTIGPSLGKENIEKGFHSTLWGFAI
                     VAAFMVVYYRLMGFFSTIALSANILFLIGILSAMQATLTLPGMAALALTLGMAIDSNV
                     LINERIREELRAGVPPQQAINLGFQHAWATIVDSNLTSLIAGIALLVFGSGPVRGFAV
                     VHCLGILTSMYSSVVVFRALVNLWYGRRRKLQNISIGSVWKPKAEMAGGKE"
     gene            complement(8304..8570)
                     /gene="yajC"
                     /locus_tag="ACFOV4_000963"
     CDS             complement(8304..8570)
                     /gene="yajC"
                     /locus_tag="ACFOV4_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFC7618993.1"
                     /translation="MNQAVAQFAPLVLIMVVFYFLIMRPQQKKFKAHQAMLAALKVGD
                     KVVLAAGFKGKVTRVGEQFFTVDIGQGTKIEVEVERNAIAAKVD"
     gene            8698..9807
                     /locus_tag="ACFOV4_000964"
     CDS             8698..9807
                     /locus_tag="ACFOV4_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone deacetylase family protein"
                     /protein_id="HFC7618994.1"
                     /translation="MSLTRLILKFYALLRLFLGKNARTAWISHPACAGHEPGANHPDS
                     PDRILCIEQALRRAGIWQHLQTIEAEEISDTRLALVHSSKYLNRLESCLPQKGKIFRL
                     DNDTAISTGSLSAAHFAAGSAVQAVDMVMNRKAWHAFCAARPPGHHAGSGKAGGFCLL
                     NNVAAGVMHAIAEYRLKRIAVIDFDVHYGDGTAEIFKDDPRILFFNLFETDLFPFPEN
                     NDMPDGGNMVHLPLPPGTGSRTFREAVRRQWLPRLAAFKPELVLLSAGFDAHRLDESG
                     RLNLHEADFAWLTHKIIQTASGCPGKIVSVLEGGYTLEPLAQSAAEHIRVLAGLGKSD
                     AATAYQKTLDPTKKRFAKPKTGQVRQPTQSDRYDI"
     gene            10170..11234
                     /locus_tag="ACFOV4_000965"
     CDS             10170..11234
                     /locus_tag="ACFOV4_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HFC7618995.1"
                     /translation="MKAARFYDKGDIRIEDIPEPTVAPGTVGINVAWCGICGTDLHEF
                     MEGPIFIPPCGHPHPISGESAPVTMGHEFSGVVYAVGEGVDDIKVGQHVVVEPYIIRD
                     DVPTGEGSNYHLSKDMNFIGLGGCGGGLSEKIAVKRRWVHPISDKIPLDQAALIEPLS
                     VGHHAYVRSGAKAGDVALVGGAGPIGLLLAAVLKAKGIKVIITELSKARKDKARESGV
                     ADYILDPSEVDVVEEVKKLTNGEGVDVAFECTSVNKVLDTLVEACKPAANLVIVSIWS
                     HPATVNVHSVVMKELDVRGTIAYCNDHAETIKLVEEGKINLEPFITQRIKLDELVSEG
                     FERLIHNNESAVKIIVSPNL"
     gene            11375..11698
                     /locus_tag="ACFOV4_000966"
     CDS             11375..11698
                     /locus_tag="ACFOV4_000966"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP diphosphatase"
                     /protein_id="HFC7618996.1"
                     /translation="MGDSVLSAIQQTITQRKSANPSESYVAQLLHKGEDKILKKVIEE
                     AGEVLMASKDKNPSHLVYEVADLWFHTMILLTHHDLKAEDVLDELARRQGLSGLAEKA
                     ARTES"
     gene            11770..12093
                     /locus_tag="ACFOV4_000967"
     CDS             11770..12093
                     /locus_tag="ACFOV4_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HFC7618997.1"
                     /translation="MDNCIFCKIAAKDIPAQTVYEDGEMVCFKDINPAAPVHLLLIPK
                     VHFDSLAHAAPEHQPLLGKMMLKVPEIAKAAGLADGFKTLINTGKGGGQEVFHLHIHI
                     MGTPV"
     gene            12140..12343
                     /gene="tatA"
                     /locus_tag="ACFOV4_000968"
     CDS             12140..12343
                     /gene="tatA"
                     /locus_tag="ACFOV4_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0043953 - protein transport by the Tat
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HFC7618998.1"
                     /translation="MGSFSLTHWIIVLIIVVLIFGTKKLRNVGKDLGGAVHDFKQGLN
                     EGTDGKEAQKDDVIEHKKDEDKA"
     gene            12347..13033
                     /gene="tatB"
                     /locus_tag="ACFOV4_000969"
     CDS             12347..13033
                     /gene="tatB"
                     /locus_tag="ACFOV4_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008320 - protein transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase protein
                     TatB"
                     /protein_id="HFC7618999.1"
                     /translation="MFDFGLGELVFVGIIALIVLGPERLPEAARTAGRLIGRLQRFVG
                     SVKQEFDTQIELEELRKAKQEFEAAAAQVRDSLKEIGTDMEGNLHDISNGLKPWEKLP
                     EQRTPADFGVDENGNPLPDAANTLSDGISDVMPSERSYASAETLGDDRQTGSTAEPAE
                     TDKDRAWREYLTASAAAPVVQTVEVSYIDTAVETPVPHTTSLRKQAISRKRDLRPKSR
                     AKPKLRVRKS"
     gene            13047..13817
                     /gene="tatC"
                     /locus_tag="ACFOV4_000970"
     CDS             13047..13817
                     /gene="tatC"
                     /locus_tag="ACFOV4_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HFC7619000.1"
                     /translation="MSETQNEQPVQPLVEHLIELRRRLMWMVIGILVCFFGMMPFAQQ
                     LYTFIANPLMANLPKDTSMIATDVIAPFFVPVKVTLMAAFLISLPHTLYQIWAFVAPA
                     LYQNEKRLITPLVLSSVSLFFIGMAFAYFLVFPVIFKFLAGVTPVGVNMATDIDKYLS
                     FILGMFVAFGTTFEVPIVVILLTKIGVVTTGQLKRARPYVIVGAFVIAAIITPPDVIS
                     QTLLAIPLILLYEAGIWFGRFFTPRSEQDGDIQPPATT"
     gene            13870..14478
                     /locus_tag="ACFOV4_000971"
     CDS             13870..14478
                     /locus_tag="ACFOV4_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030428 - cell septum [Evidence IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family nucleotide pyrophosphatase"
                     /protein_id="HFC7619001.1"
                     /translation="MNTLYLGSNSPRRMEILTQLGYQVVKLPANIDETVRQNEDPARY
                     VQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVVSDGIILGKPHSQAEAIEFLNRL
                     SGKQHTVLTAVCIHYRGNAENRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG
                     IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRSPLSALKP"
     gene            14487..14840
                     /locus_tag="ACFOV4_000972"
     CDS             14487..14840
                     /locus_tag="ACFOV4_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2069 domain-containing protein"
                     /protein_id="HFC7619002.1"
                     /translation="MNRQTAYLLTSFSLIALIILSLSWELWIAPLRPGGSWLALKALP
                     LCLPLSGILKKKIYTYQYSSMLVLIYFAEAVMRLFDAYPAEQICAALSAVFSIIFFIS
                     CLSFVKQYKETNNAR"
     gene            14830..16644
                     /locus_tag="ACFOV4_000973"
     CDS             14830..16644
                     /locus_tag="ACFOV4_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Wzy polymerase domain-containing protein"
                     /protein_id="HFC7619003.1"
                     /translation="MPAETTVSGARPAAKLPIYILPCFLWIGIIPFTFALRLQPSPDF
                     YHDAAAAAGLIVLLFLTAGKKLFDVKIPPISFLLFAMAAFWYLQARLMNLIYPGMNDI
                     VSWIFILLAVSAWACRSLVAHYGQERIVTLFAWSLLIGSLLQSCIVVIQFAGWEDTPL
                     FQNIIVYSGQGVIGHIGQRNNLGHYLMWGILASAYLNGQRKIPAALGVICLIMQTAVL
                     GLVNSRTILTYIAAIALILPFWYFRSDKSNRRTMLGIAAAVLLTALFQFSMNTILETF
                     TGIRYETAVERVANGGFTDLPRQIEWNKALAAFQSAPIFGHGWNSFAQQTFLINAEQH
                     NIYDNLLSNLFTHSHNIVLQLLAEMGISGTLLVAATLLTGIAGLLKRPLTPASLFLIC
                     TLAVSMCHSMLEYPLWYVYFLIPFGLMLFLSPAEASDGIAFKKAANLGILTASAAIFA
                     GLLHLDWTYTRLVNAFSPAPDDSAKTLNRKINELRYISANSPMLSFYADFSLVNFALP
                     EYPETQTWAEEATLKSLKYRPHSATYRIALYLMRQGKVAEAKQWMRATQSYYPYLMPR
                     YTDEIRKLPVWAPLLPELLKDCKAFAAAPGHPEAKPCK"
     gene            16834..17511
                     /gene="misR"
                     /locus_tag="ACFOV4_000974"
     CDS             16834..17511
                     /gene="misR"
                     /locus_tag="ACFOV4_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003684348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator MisR"
                     /protein_id="HFC7619004.1"
                     /translation="MSRVLLVDDDALLTELLTEYLSAEGLNVRSVPDGEAGVQEILSG
                     QYDVVVLDSMMPKMNGLDVLKNVRARSTVPIIMLTAKGDDIDRIIGLEMGADDYVPKP
                     CTPRELLARINAILRRAQHSGEQNNAPNSISVSDVVLYPAKRQASVKDMPLELTSTEF
                     NLLEVLMRHAGQVVSKETLSVEALDRKLAKFDRSIDVHISSIRHKLGDASLIQTVRGL
                     GYLFVKN"
     gene            17524..18930
                     /gene="misS"
                     /locus_tag="ACFOV4_000975"
     CDS             17524..18930
                     /gene="misS"
                     /locus_tag="ACFOV4_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     MisS"
                     /protein_id="HFC7619005.1"
                     /translation="MKLFQRIFATFCAVIVCAIFVASFSFWLVQNTLAENQFNQRRTI
                     ETTLMGSIISAFRARGDAGAREILTEWKDSPVSSGVYVIQGDEKKDILNRYIDSYTIE
                     RARLFAAGHPHSNLVHIEYDRFGEEYLFFTKDWDKLQARRLPSPLLIPGLPLAPIWHE
                     LIILSFIIVVGLLMAYILAGNIAKPIRILGNGMDRVANGELETRISQQVDDRDDELSH
                     LAIQFDKMVEKLEKLVAKERHLLHHVSHEMRSPLARMQAIVGLIQAHPQKQEQYLKRL
                     EGELTRMDTLAGELLTLSRLETSNMALEKESLKLLPFLGNLVEDNQSIAQKNGQTVTL
                     SVDGKIPENTTILANESYLYRAFDNVIRNAVNYSPEGSTILINIGQDHKHWIIDVTDN
                     GPGVDEMQLPHIFTAFYRADSSANKPGTGLGLALTQHIIEQHCGKIIAENIKPNGLRM
                     RFILPKKKTGSKTEKSAN"
     gene            19048..21474
                     /locus_tag="ACFOV4_000976"
     CDS             19048..21474
                     /locus_tag="ACFOV4_000976"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC7619006.1"
                     /translation="MSAQTDPGYFFMPNHIILIGASERPYSLGERVLSNLLSTPFQGK
                     ITPVNPRHHTIAGLPAYTSLNKIPGNADLIIAVTLPDSYDTLFKTCRKKQLRHIILIQ
                     DWDSLSAAELHTAETAIRKHHGNGLNITACTTAGIQLPSLGLNISTQDGYAAGHTAIL
                     TGNAAVSRQIDNILNKLRQGTSRHISLHPGISPITSSDWLNRFGHSLHTKTAVLHYNP
                     EEDQRKLFSAIRQFTRHTPLILHITCRTTETDRAVLHCLARHCNFLISFNADDLEAAL
                     RAQLSDLPPLSRLDILSDTPAEWLNAHAPKTLALHFPNLPHHIRNGHLTGTPTPSICH
                     DIASRQLARPDTQAVLTILSPSGHEDYKKTARALIRLSEQTAKPLLVSSPFSDGITHF
                     DTPTQAIRTLSYRNTAAALKQAQLDIAPPQPCRLKTPQPQNIKKALAAANPSLLAEAL
                     HLPPYRHTTHNAVQFQFGSHPLYGDILTACCNGQTTAVLPPFTTLDSRHLARFAELDG
                     TQTLDQFLHTLTVIPEYRQHILGITLNLNGGQYSSDFILKTPETHDTPKRKNTGKAAQ
                     TLEHAAAKMQSAAAYLKHKNPTAAEFLRHTSEAAAELLGSKTETGAAVPNVLAPYPAA
                     HLKTLSLKNNTTVTITPLLPEDAEAKQQFVRSLSPEARYTRFMTHTNELPAATLARLC
                     NPDYHCEAAWTARDADSNIVAVVRHSRLNRNECEFGITLAEHMRGSGLAQKMMELIIQ
                     TAAQQGYRTMSADILKTNTPMIKLAEKSGFTLKESDTEKNLYRAYLNLAADKTTEKTN
                     KNLHTDHKIT"
     gene            21519..21764
                     /gene="rpsP"
                     /locus_tag="ACFOV4_000977"
     CDS             21519..21764
                     /gene="rpsP"
                     /locus_tag="ACFOV4_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFC7619007.1"
                     /translation="MVVIRLARGGSKHRPFYNVIVTDSRSRRDGRFIERVGFYNPVAN
                     EKQERVRLNADRLNHWIAQGAQVSDSVAKLIKEQKAA"
     gene            21780..22289
                     /gene="rimM"
                     /locus_tag="ACFOV4_000978"
     CDS             21780..22289
                     /gene="rimM"
                     /locus_tag="ACFOV4_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003748672.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFC7619008.1"
                     /translation="MTDTQNRVAMGYIKGVFGIKGWLKIAANTEYSDSLLDYPEWHLV
                     KDGKTISVTLEAGKVVNSELQVKFEGINDRDLAFSLRGYTIEIPREAFAPTEEDEYYW
                     TDLVGMTVVNKDHTVLGKVSNLMETGANDVLMIDGEHGQILIPFVSQYIETVDTGSKT
                     ITADWGLDY"
     gene            22289..23038
                     /gene="trmD"
                     /locus_tag="ACFOV4_000979"
     CDS             22289..23038
                     /gene="trmD"
                     /locus_tag="ACFOV4_000979"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFC7619009.1"
                     /translation="MLIQAVTIFPEMFDSITRYGVTGRANRQGIWQFEAVNPRKFADN
                     RLGYIDDRPFGGGPGMIMMAPPLHAAIEHAKTQSSQAAKVIYLSPQGKPLTHQKAVEL
                     AELPHLILLCGRYEGIDERLLQSSVDEEISIGDFVVSGGELPAMMLMDAVLRLVPGVL
                     GDMQSAEQDSFSSGILDCPHYTKPLEFQGMAVPEVLRSGNHGLIAEWRLEQSLRRTLE
                     RRPDLLEKRVLIPKESRLLETIRQEQREIQS"
     gene            23054..23419
                     /gene="rplS"
                     /locus_tag="ACFOV4_000980"
     CDS             23054..23419
                     /gene="rplS"
                     /locus_tag="ACFOV4_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFC7619010.1"
                     /translation="MNLIQQLEQEEIARLNKEIPEFAPGDTVVVSVRVVEGTRSRLQA
                     YEGVVISRRNRGLNSNFIVRKISSGEGVERTFQLYSPTVEKIEVKRRGDVRRAKLYYL
                     RGLTGKAARIKEKLPARKG"
     gene            23737..24462
                     /locus_tag="ACFOV4_000981"
     CDS             23737..24462
                     /locus_tag="ACFOV4_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010361246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFC7619011.1"
                     /translation="MSIIVENLTVSYRRRPAVHHVDITFEEHSMWAVFGPNGAGKSTF
                     LKSLMGLQPIDTGSIRLDGLTRQNIAYLPQQSDIDRSQPMTVFDLAAMGLWYEIGFFR
                     GINAVQKQRVHESLERVGMRQFAGRQIAHLSNGQFQRVLFARMLVQNAKFLLLDEPFN
                     AVDARTTYELLDVLQKCHCGGHAIIAVLHDYEQVRAYFPNTLLLAREKIAAGATETIL
                     TEPYLAQANAKMQQQESPEWCAS"
     gene            24498..25373
                     /locus_tag="ACFOV4_000982"
     CDS             24498..25373
                     /locus_tag="ACFOV4_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFC7619012.1"
                     /translation="MNPYDLLITPFAEFDFMRYALVSVFCLSLSAAPVGVFLVMRRMS
                     LIGDALSHAVLPGAAVGYMFAGLSLPAMGLGGVAAGMLMALLAGLVSRFTTLKEDANF
                     AAFYLSSLAIGVVLVSKNGSSVDLLHLLFGSVLAVDIPALQLIAAVSTLTLLTLAVIY
                     RPLVLESIDPLFLKSVGGKGGLWHVLFLVLVVMNLVSGFQALGTLMSVGLMMLPAITA
                     RLWAKHMGALILLSVLTALLCGLSGLLISYHIEIPSGPAIILCCSVLYLFSVILGKEG
                     GILTKWLKNHRHHTT"
     gene            25450..26364
                     /locus_tag="ACFOV4_000983"
     CDS             25450..26364
                     /locus_tag="ACFOV4_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003696733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFC7619013.1"
                     /translation="MKHPKLTLIAALLTTAATAAPLPVVTSFSILGDVAKQIGGERVS
                     IQSLVGANQDTHAYHMTSGDIKKIRSAKLVLLNGLGLEAADVQRAVKQSKVSYAEATK
                     GIQPLKAEEEGGHHHDHDHDHEGHHHDHGEYDPHVWNDPVLMSAYAQNVAEALIKADP
                     EGKVYYQQRLGNYQMQLKKLHSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIA
                     PQGVSSEAEPSAKQVAAIIRQIKREGIKAVFTENIKDTRMVDRIAKETSVNVSGKLYS
                     DALGNAPADTYIGMYRHNIKALTNAMKQ"
BASE COUNT         6815 a         7904 c         6085 g         5605 t
ORIGIN      
        1 tgcctgcgac gcttaacggc tgtctttcca ctgataatat ttcgagccga ggaaagaacc
       61 gagtttgcgc aaaaacggtt gcaggataat attcggctgg cgcaaccgct caaacggctt
      121 cagacggcat tcgtccccta aaattgcttc ggcaaccgcc agacctgcaa tgcctgttat
      181 cgccatcccg tgtccggaat aaccttgtgc ataaaaaaca tttgcggcca aacgtccgaa
      241 atgcgggaca aggttggcgg taatgtcgca ctccccgccc cacgaatatt cgattttgac
      301 atcgtcaagc tgcggaaaaa ctttaagcat atcttggcgg acaagctcgg tcatacgcgc
      361 aggattgtcg ataaactcgt tatccttacc gccgaaaagc agtctgccgt ccgcgctgag
      421 gcggtaataa tccaaaatat ggcggttgtc gcatactgcc atattgttac ggataagccc
      481 ttttgcgcgc gcccccaagg gttcggtcgc aataataaag gtgctaacgg caatcgcctt
      541 gcgttccaaa ggctggaata tcgggttcaa acctgcatag gtattgacgg catacaccag
      601 atttttgcat tcgacgctgc cttcgggcgt gtaaaccagc caaccgtttt gatgcggttc
      661 gatgcgcgtc atcggggact gctcgaaaat ctgcgcgccg gcttcggcag cggcaccggc
      721 aacacccaac gtgtaattga gcggatgcag gtgtccggat aaggggtcga attgtgcccc
      781 ttggtacata tcgctgtcaa gctgctgctt cagttcagtg ttatcccaga gttgataatg
      841 agttgcaccg taatattttt gggcgtgctc atgccattgt tgcaattctt cccaatgctg
      901 cgaacggatg gcaaccgtgg cataaccgcg ctgccaatcg caatcaatgg catgtttgcg
      961 gacgcgttcg tccaccagtt cgaccgcctg caaagactgt tgccaaaacc attgcgcttg
     1021 ctccaaaccg acctgttttt caatttcctc cataccgcag gcgtaatcgc tgataacctg
     1081 cccgccactc cgtcccgacg cgccgaaacc gatacgcgcg gcttccaaca caaccgtttc
     1141 atgtccctgc tccgccaagg gcaatgcagt gcacaaacca ctcaatccgc cgccgatgat
     1201 acaggtatcg gttttcagac ggcattgaag tttcggataa acagtatgag gattaaccga
     1261 actgaaataa taagaaggca gatattcttg aaaatcaggg cgaatcattg tgtttgcttt
     1321 atcgggtata ttttcggacg gaatgataca ggctgtcgag ccatatcgtc caaacagaaa
     1381 atcggttgaa gaaaacaggc tgacccagtc atgcggtcag cctgccttat taattaattt
     1441 gctttctcgg cagccaattt ttcttggcgg taggcttctg ccgcttctcg gtcacgcttg
     1501 gttgcctgcc tcatcatcca ataattgacg atgatgacca atgttccgat gatgccgatc
     1561 aggatggttg ccaaaacgtt catctgcgga tcaagaccca gcttgatttt ggagaaaatc
     1621 acctgcggca atgtggatga accggggccg gagaggaatg aggtaatcac caaatcatcc
     1681 aaagacaggg taatgccgag cagaaagcct gaagcgatgg caggggcaat caaaggcaaa
     1741 gtgatgacaa aaaagatttt cagcggacgc gcgcccaaat ccattgcggc ttcttcgagc
     1801 gactggtcaa gctcaaccag acgcgaacgg ataacaacgg taatgtacgc catacacagc
     1861 gtcgtatgtc cgaggaagat ggtgaaaaag ccacgatcga agtagagatg ttgtaaccat
     1921 tcgctgccct gcaaaaatat ctgtacctga ataatcagca gcagcataga cagaccggta
     1981 atcacgtcgg gcatcaccat aggtgcggaa atcataccgg cgaacaaggt actgccgcga
     2041 aaacgtttaa tccgcgccat cgcatagcct gccagcgtgc ccaaaacgac ggcagcaagc
     2101 gaagacacaa cggcaatccg cagcgacagc caagcggctt ccaagatggt gtcgttttcc
     2161 agcaatgcgc cgtaccactt ggtcgaaaag ccgccccaaa cggttaccag cttggattcg
     2221 ttaaacgaat agatgaccaa aacaaccagc gggatataca gaaacgccag cgacagtgcc
     2281 aacatcagtt tcaagaacca agataatttg gatttctgca ttatttggct ccttcttcca
     2341 attcgcggtt ttcataatgc tgaaacaggg caatcggcac gaccagcagc gcgaccatca
     2401 cgacggcgac ggcggaagcc agcggccagt tgttttgatc gaagaacgcc tgccacaaga
     2461 ctttaccaat catcaggttt tccgaaccgc cgaccagctc gggaatgacg aactcgccga
     2521 cagcagggac gaaaaccagc atggagcctg caataatgcc ggttttcgac aaaggcaggg
     2581 taatcgtcaa gaacgatttg accggccccg cgcccaaatc ggaagccgct tcaagcaggc
     2641 ggttgtcgag tttcaccagt tgcgtgtata gcggcagaat cataaacggc agataggcgt
     2701 aaaccatcac caaattgagc gaaaaggcat tgtagaacaa atccaaaggc tcgctgataa
     2761 tacccatttt aatcaacagg ttgtttacaa tgccgttatg cccgagcaga cccatccacg
     2821 catagacgcg caacaggaac gatgtccaaa agggcagcat aatggcaagc agcaaaccat
     2881 tgcggacaga aggattggca cgagaaatcg cataggcggt cggataaccg accaacagac
     2941 aaattaccgt cgtagtcagc gcagtcttaa ttgaagacca ataagtcatc agatagatat
     3001 tgctgttttc accgtcgccg aacggattga gcgtactcca aaaattttgg aagatgtctg
     3061 cataattttg gtagctgaca gcaatattca gacgacccaa atcctcatct atcgtcgtta
     3121 aaggagtaaa cggcgggatg gcgatttctt gttcggcaaa gctgattttc agcacgatgg
     3181 cgaacggaat cagaaacagc accaaaagcc aaatatacgg tacggcaatc accgcacgct
     3241 gccccggacg gcggaacagt ttgtttttca gtttattaag gttcattgca ttccccttaa
     3301 atcaacggaa cagtggcgta ggctggtttt ccggccagct gatatagacg gtttcgtccc
     3361 aagttggcgg tgtaatgttg cgcacatacc agtaaggggc ggggacttgg ctcttgacga
     3421 cgcgcccgtt ggagagtttg atatggtata tggcgaagct gcccaaatag gcgatttctt
     3481 ttaccgtgcc tttcgcccag ttgtagtcgc ccaaatattc gggtttttct ttatataaat
     3541 caatatcctc tggtcgaata ctaacccaaa ggtcctgctc gctcggacca cccaaaccgt
     3601 ggtcgatgcg gacgtggttt tccaaacctt cgcattcgat aacggcatag tcggcatgat
     3661 cttcaatcac cacaccgtca aagatgttgg tttcgccgat aaactcggca gtgaagcggc
     3721 tgttgggata gtcgtacacg tcgctgggtg tgccgacttg ctgcaactga ccgtcggaca
     3781 taatggcgat gcgggtcgcc atcgtcatcg cctcttcttg gtcgtgtgta accataatac
     3841 aggttacgcc gacttgttcc agcgtattga ccaactcaag ctgggtttgc tggcgcagtt
     3901 ttttgtccaa cgcgccgagg ggctcatcca gcagtagaat tttcggacgt tttgccagac
     3961 tgcgtgccaa agcaatgcgc tgctgctgac cgccggacaa ttggtgcggt ttgcgtttag
     4021 caaatttggt catctgaacc aggcggagca tttcttcgac gcgcgcggcg atttcgcctt
     4081 taggcatttt gtcctgtttc agaccgaagg caatgttttg ttctacggtc atatgcggaa
     4141 aaagcgcgta actttggaac atcatattga tggggcgatc atagggtgca agtttggtaa
     4201 tatcctgacc atcaaggata atttttccct gattgggact ttccataccc gccagcatac
     4261 gcagcagcgt ggattttccg ctgccggaac tgcccaaaag agcgaaaatt tcgtgttgat
     4321 aaatgtccaa gtcgatgtta tcgacagcgt aattgtcacc aaactttttc accaaacctt
     4381 ggatttgcag ataaggcttg gttgaagacg cagtggttgc ggtcataatg gcaatactcc
     4441 aataaaaaga cgagtaccgg caaaacggat tttcgaatgg gtgataaaaa gctgtttgat
     4501 tgctggcggg agtcgcaacg tctgatgccg tctgaaactc ttgtgaagcg cacgggcagc
     4561 atgaaatgga acaagattcc aaagaacttt atattatatt agtttatgcg gttttcgggc
     4621 aatatagtgg attaaattta aaccagtaca gcgttgcctt gccttgccgt actatttgta
     4681 ctgtctgcgg cttcgtcgcc ttgtcctgat ttaaatttaa tccactataa atatggattt
     4741 gagcttgtcg gaaagcaaca gaaaagaaaa caccgcccat ttttctgggc ggtgtcggaa
     4801 agcgtaatta tttacgcaga cccaagcggg taatcaacgc gcgatacgta tcgggctggg
     4861 tacggcgcaa gtaggccagc aggcggcggc gttggctgac cattttcaac aggccgcgac
     4921 ggctgtggtg gtcttttggg ttggctttga agtggggggt caggtcgttg atgcggaaag
     4981 tcaacagagc gacttgtact tcggaagagc cggtgtcgcc ttctttgcgt tggaaatctt
     5041 taacgatttg tgctttttgt tctacggtca gtgccataat gaaaactcca aaaatataag
     5101 aatccccata gggattcaga caagtttgcc aagcctgaag acaacggcaa actccctatg
     5161 cccaagatag gacaacgtgg cattatgaca caattcccgc atttctgcac aatattttaa
     5221 gaccgtggaa gtaaccgtta aaaatgccgt ctgaagcatt gtctgcttga gacggcaatg
     5281 ttcagacggc atatgcgctt caaaccacga tttcttcttt cttcttcggt tctttaccga
     5341 tattgtcgcg gctcaaaccg aacattagca gaagcgggct ggcaaccaat acggaagaat
     5401 aaatgccgaa cacgatgccg atggtcaacg ccatagaaaa gccgtgcaag gccgtaccgc
     5461 cgaacaccag catggatacg accatcgcct cggtcgaacc gtgggtaatg atggtgcggc
     5521 tcatcgttgc ggtaatcgcg ttgtcgatga cttccggcac ggcatgtccg cgcatcgccg
     5581 gcttgcggaa gttttcacgg atacggtcga agacgacgac ggattcgttc acagaatagc
     5641 ccaatacggc aaggataccc gccaagacgg tcagcgaaaa ttcccattgg aagaaggcaa
     5701 agcagccgag aataatcacg atgtcgtgca tattggcgat aatggcagat acggcaaaac
     5761 gccattcgaa acgcatcgac aggtaaataa tgatgccgat aacgacaaaa cctaaagcca
     5821 tcaatccatt acttaccaat tcctcaccaa cttgcgggcc gataaattcg acttggcgca
     5881 aagtaacgtc gggactgtct tttttcagca aatccataac ctgattggac aactgtgcgg
     5941 aagtaacacc ttctttgttc ggcaggcgga tcatgatgtg tttgttcgta cccaatgcct
     6001 gaacctgtac atcacctatt ttcagcgtat cgaggcgttc gcgcatctta ttgacatccg
     6061 caccctgctg atattggact tccattaccg tgccgccggt aaattcgaca gagaaattca
     6121 gacctctggt aaccaaaaag aatacggcgg caataaaggt aaccaacgaa ataaaggtcg
     6181 tcagtttgcc gtagctcata aacggaatat cgcgtttgat tttaaagagt tccatagctt
     6241 actccttgcc tcctgccatt tcggctttcg gcttccacac cgaaccgatg gaaatattct
     6301 gcaatttgcg tctgcgtcca taccacagat tgaccaacgc acggaatacg acgacggacg
     6361 aatacatcga agtcagaata cccaaacagt gtacgaccgc aaaaccgcgt accgggccgg
     6421 aaccgaatac caaaagcgcg ataccggcaa tcagcgaagt caggttggaa tcgacaatgg
     6481 tcgcccatgc gtgttggaaa ccgagattga ttgcctgctg cggcggcacg ccggcacgca
     6541 attcttcgcg gatacgttcg ttaatcaaga cgttggagtc gattgccata cccaaagtca
     6601 acgccagcgc ggccataccc ggtaacgtca acgttgcctg catggcagac aaaataccga
     6661 ttaggaacag tatgttggca ctcaatgcaa tggtagaaaa gaaacccatc agacgatagt
     6721 aaaccaccat gaatgcagca acgatggcaa aaccccataa agtcgaatgg aagccttttt
     6781 cgatgttctc cttacccaaa gacggaccga tggtacgttc ttcgacaatc tgcatcggcg
     6841 cggcaagaga accggcacgc aacagcaaag acgtatcatt ggcttcggct gtcgtcatgc
     6901 ttccggaaat ttccacgcgt ccgccggtaa tggcagtacg gataaccggc gcggttacaa
     6961 cctcggattt tccttggtcg atcaaaacca tcgccatgcg tttgccgaca tttgcggcag
     7021 tcagttcgcc aaaaatgctg ccacccgcgc tgtccaagct cagactgaca gcaggtgcgc
     7081 ccatttggtc gaaactcggt tgcgcatcgt tgatgttgtc gcccgtcagc tcgacctgtt
     7141 tgctgattag cagagtttcg ggacgatctc cgccgcttga aagcagctca taaccgctcg
     7201 gcacgttgcc ttccaatgcc tcgcgcaact tggcaggatc gtcctccacc atacgcaatt
     7261 ccaaagtcgc ggtacggccg atgatgtctt ttgccttggc agtatcctga acgcccggaa
     7321 gctgcacgac gatacggtcg gcaccggact gctggatgac gggttcggcc acgcccaact
     7381 cgttcacacg gttgtgcagg gtagtgatgt tctgtttgac cgcatcggaa cgcactttat
     7441 tgaccgcctc ttccgaaagc gtcaagacga tattgctgcc gtctgaattc agcgttgctt
     7501 caggaaacag cttgcgcaac tgcggcagtg ccttttgcac atcacctgca tcctgcaaag
     7561 ggacggtcag gctgtttcca gcctgacgca ccgtgccgct gcggattttt tcgcggcgca
     7621 gttcgcggcg gatgtcgccc gaataacgtt caaacgtttt ctgcatcgcc gctttcatat
     7681 cgacctgcat ggtgaaatgc acgccgccgc gcaggtccaa acccaaaaac atcggattgg
     7741 ctttgatttt cgccatccat tcggggctgt ccgccaacag gttgagcgcg gtaatatacc
     7801 cttcgcccaa agtgttttcg atgacgtcgc gcgctttaag ctgcgtttct gtgtctttga
     7861 aacgcacttt cagtgaattg tccacaacaa acatcccgtc ggtctgaata cctgcgtttt
     7921 tcagcgcggc atccactttg gattgagtct gttcgttgat gatgatggct tgtcggttgg
     7981 tcgatacctg cacggcgggt gtttcgccga ataggttggg cagcgaatac actgcggcaa
     8041 ccgcaatcgt gaacacaatc agcagatatt tccataaagg ataacggttc atcattgttc
     8101 cttaatggtt ggaaccccac cctttcggtg gtgtcggaat cgggctattt cagaagaggc
     8161 aaaaaccctt cccagccagg caagaccgga aggcggcatc ttgaatatgc cgccctgcgt
     8221 gtcggaacat ggtcaagcct tcggttggaa ttcaaaacaa agtgccgcat tcgggctttc
     8281 cagatgcggc ttgtcggcac aaatcaatcg acttttgcgg caatcgcatt gcgttctact
     8341 tcgacctcga tttttgtacc ctgtccgata tccacggtaa aaaactgttc gccgactctg
     8401 gttaccttac ccttgaaacc tgccgccaag accactttgt cgccgacttt caaggcggca
     8461 agcattgcct gatgcgcttt gaatttcttt tgctgcggac gcatgatcag gaagtagaac
     8521 accaccataa tcaacactaa aggagcaaat tgtgcaacag cttgattcat aatttatccg
     8581 ttctttctaa tatggttgaa aatcgagagg ggtatataat aacataagac cgtaaacaat
     8641 atatcgggtt tgccgtccgt accgaccgta taccgcagcc tgcccgtcca caaacccatg
     8701 tccttgaccc gcctaatctt gaaattctat gcactgttgc gccttttttt gggcaaaaac
     8761 gcccgcaccg catggatttc gcatcccgcc tgtgccgggc acgaacccgg cgcaaaccat
     8821 cccgattcgc ccgaccgcat cctctgcatc gagcaggcat tgcgccgcgc cggtatttgg
     8881 cagcacctcc aaaccataga ggcggaagaa atcagcgata cgcgcctcgc acttgtccac
     8941 tcgagcaaat atctgaaccg tttggaatct tgcctgcccc aaaaaggcaa gattttccgc
     9001 ctggataacg acactgcaat cagcacaggc tcgctgtctg ccgcacactt tgccgccggt
     9061 tcggcagttc aggcagtcga catggtcatg aaccgtaaag catggcatgc cttttgcgcc
     9121 gcccgcccgc ccggacacca tgcgggcagc ggcaaagccg gcggattctg cctgctgaac
     9181 aacgttgccg ccggcgtcat gcatgccatt gccgaatacc gcctgaaacg cattgccgtc
     9241 atcgatttcg atgtccacta cggcgacggt acggcagaaa tattcaaaga cgatccgcgc
     9301 atcctgtttt tcaacctgtt tgaaaccgac cttttcccct tccccgaaaa caacgatatg
     9361 cccgacggcg gcaatatggt gcacctgccc ttgccgccgg gaacgggcag ccgcacattc
     9421 cgcgaagccg tccgcagaca gtggctgccc cggcttgccg cattcaaacc cgaactggtg
     9481 ctgctgtcgg caggattcga cgcacaccgt ctagacgaat cgggcaggct caacctgcac
     9541 gaggcggatt ttgcctggct gacacacaaa atcattcaga cggcatcggg ctgccccggc
     9601 aaaatcgtat ccgtactcga aggcggctac acccttgaac ctctggcaca atctgctgcc
     9661 gagcatatcc gcgtgctggc ggggctgggc aaatccgatg ccgcaaccgc ctatcagaaa
     9721 acactggacc caacaaaaaa acggtttgcc aaaccgaaaa ccggacaggt gcgccaacct
     9781 acccaatccg accgttacga catatagtgg attaacaaaa atcaggacaa ggcgacgaag
     9841 ccgcagacag tacagatagt acggaaccga ttcacttggt gcttcagcac attagagaat
     9901 cgttctcttt gagctaaggc gaggcaacac cgtactggtt tttgttaatc caccataaat
     9961 gccatctgaa gccgattcgg ttttcagacg gcatcattat ttgacctgac gcaaacagaa
    10021 agccttccgc gtgcttaaac acatctcttg tagtaaaata tctaaacaga ttcaactgga
    10081 aacggtcagg cttcttcacg ccattcccat ttcaaccgcc gcctgccaga ttcagacggt
    10141 attcctactt gaaaacaagg agcgttacaa tgaaagcagc acgtttttac gataaaggcg
    10201 acatccgcat cgaagacatc cccgaaccga ccgtcgcccc cggcactgtc ggcatcaatg
    10261 tcgcctggtg cggcatctgc ggtactgacc tgcacgaatt catggaaggc ccgattttca
    10321 ttccgccttg cggtcatccg cacccgattt ccggcgagtc cgcacccgta acgatgggac
    10381 acgagttctc cggcgtggtc tatgccgtcg gcgaaggcgt ggacgacatc aaagtcggcc
    10441 aacacgtcgt ggtcgaaccc tacatcatcc gcgatgacgt accgaccgga gaaggcagca
    10501 actaccacct ctctaaagac atgaacttca tcggcttggg cggctgcgga ggtggcttgt
    10561 ctgaaaaaat cgctgtcaaa cgccgttggg tgcatccgat ttccgacaaa atcccgttgg
    10621 atcaagccgc tttgatcgaa ccgctgtctg tcggacacca cgcctatgta cgcagcggcg
    10681 cgaaagcagg cgacgtcgca ttggtcggcg gcgcaggtcc gatcggtttg ctgttggctg
    10741 ccgtgttgaa agccaaaggc atcaaagtca tcatcaccga gttgagtaaa gcacgcaaag
    10801 acaaagcgcg cgaatccggc gttgccgact acatcctcga cccgtccgaa gtcgatgttg
    10861 tcgaagaggt gaaaaaactg accaacggcg aaggcgtgga cgtggcattc gaatgtacca
    10921 gcgtgaacaa agtgttggat actttggtcg aagcctgcaa acctgccgcc aatttggtta
    10981 tcgtatccat ctggagccac cctgcaaccg tcaacgtcca cagcgtcgtg atgaaagagc
    11041 tggatgtgcg cggcacgatt gcctactgta acgaccacgc cgaaaccatc aaactggtcg
    11101 aagaaggcaa aatcaacctc gaacccttca tcacccagcg catcaagctg gacgaactgg
    11161 tttccgaagg cttcgagcgt ctgatccaca acaacgaatc cgccgttaaa attattgtga
    11221 gtccaaacct gtaagcaaat tacatttgca acagcacaaa tgccgtctga aacgctcaga
    11281 cggcattttc caacgaagcg caacaggcgt attgcccgag agcagccgtt tagcctatca
    11341 ttccgaacaa acagaaacaa acagaaggaa aatcatggga gattccgtac tatccgccat
    11401 ccaacaaacc atcacccagc gaaaatctgc caatccgtcc gaatcttacg tcgcacagct
    11461 cttgcacaag ggcgaggaca aaatcctaaa aaaagtgatt gaagaggcgg gcgaagtgtt
    11521 gatggcatcc aaagacaaaa acccgtccca cctggtttac gaagttgccg acttatggtt
    11581 tcacaccatg attcttctga cacaccacga cctgaaggcg gaagacgtat tggacgaact
    11641 tgcgcgccgc caaggtttgt cgggcttggc cgaaaaagcc gctcgcacag aatcttgaat
    11701 ttatattaaa atccgcactt tcccacattc aatccgtctg accgcttttc agacggcaac
    11761 ggagccgtta tggacaactg tattttctgc aaaatcgccg ccaaagacat tccggcgcaa
    11821 accgtctatg aagacggcga aatggtttgt ttcaaagaca tcaaccccgc cgctccggtt
    11881 catctgctgc tgattcccaa agtccatttc gattcgttgg cacacgccgc gcccgaacat
    11941 cagccccttt tgggaaaaat gatgctgaaa gttcccgaaa tcgccaaagc ggcaggactg
    12001 gcagacggct tcaaaaccct gatcaacacc ggaaaaggcg gcggacaaga ggtcttccac
    12061 ctgcatatac acatcatggg cacacccgta taaaccgtta tttcacaatc aacccctaat
    12121 acttacttaa ggatacatca tgggcagttt ttctctgacg cactggatta tcgtactgat
    12181 tatcgtcgtt ttgatattcg gcaccaaaaa actgcgcaac gtcggcaaag acctcggcgg
    12241 tgcggttcat gacttcaaac aggggctgaa cgaaggtaca gacggcaaag aagcccaaaa
    12301 agacgatgta atcgaacaca aaaaagacga agacaaagcg taatttatgt ttgatttcgg
    12361 tttgggcgag ctggtttttg tcggcattat cgccctgatt gtcctcggcc ccgaacgcct
    12421 gcccgaggcc gcccgcaccg ccggacggct catcggcagg ctgcaacgct ttgtcggcag
    12481 cgtcaaacag gaatttgaca cgcaaatcga actggaagaa ctgaggaagg ccaagcagga
    12541 attcgaagct gccgccgctc aggttcgaga cagcctcaaa gaaatcggta cggatatgga
    12601 gggtaatctg cacgacattt ccaatggtct gaagccttgg gaaaaactgc ccgaacagcg
    12661 cacgcctgcc gatttcggtg tcgatgaaaa cggcaatccc cttcccgatg cggcaaacac
    12721 cctatcagac ggcatttccg acgttatgcc gtccgaacgt tcctacgctt ccgccgaaac
    12781 ccttggggac gacaggcaaa ccggcagtac agccgaaccc gcggaaaccg acaaagaccg
    12841 cgcatggcgg gaatacctga ctgcttctgc cgccgcaccc gtcgtacaga ccgtcgaagt
    12901 cagctatatc gataccgctg ttgaaacccc tgttccgcat accacttcgc tgcgtaaaca
    12961 ggcaataagc cgcaaacgcg atttgcgtcc caaatcccgc gccaaaccta aattgcgcgt
    13021 ccgtaaatca taaagagagc aatccggtgt ccgaaacaca aaacgaacaa cccgtccaac
    13081 cgcttgtcga gcatctcatc gagctgcgcc gccgcctgat gtggatggtt atcggcattc
    13141 tcgtctgctt tttcggcatg atgccgtttg cccaacaact ctatactttt atcgccaacc
    13201 cgctgatggc aaacctgccc aaagacacca gcatgattgc caccgatgtc atcgcaccgt
    13261 ttttcgtgcc ggtcaaagtt accctgatgg cggcattttt aatttcgctg ccgcatacgc
    13321 tctaccaaat ctgggcattt gtcgcccccg cactctacca aaacgaaaaa cgcctgatta
    13381 cgccgctcgt cctctccagc gtcagcctgt ttttcatcgg tatggcattt gcctactttt
    13441 tggttttccc cgtcattttc aaattccttg ccggcgttac ccctgtcggg gtcaatatgg
    13501 cgacagacat cgacaaatac ctctccttca tcttggggat gtttgtcgca ttcggtacaa
    13561 cgtttgaagt ccccattgtc gttatcctgt taaccaaaat tggtgtggta acaaccggac
    13621 agctcaaacg cgcccgcccc tatgtgattg tcggcgcgtt tgtcattgcc gccatcatca
    13681 cgccgcccga tgtgatttca caaaccctgc ttgccattcc gctgattctc ttatacgaag
    13741 caggtatttg gttcggacgc tttttcacgc cacgttcaga acaggatggc gacatacagc
    13801 cgcctgcaac aacctgacac tatgccgtcc gaacctccgc ctcataccgc aacagattaa
    13861 ggaatacctt tgaataccct ctatttaggt tcaaacagcc cgcgccgaat ggaaatcctg
    13921 acacagttgg gctatcaggt cgtcaagctg cctgccaaca tcgacgaaac ggtcagacag
    13981 aacgaagacc ctgcccgtta cgttcaaagg atggcagaag aaaaaaaccg aaccgccctg
    14041 accctctttt gcgaaaccaa cggcacaatg cccgatttcc ccctgattac cgccgacacc
    14101 tgcgtcgttt cagacggcat catattaggc aaaccccact cccaagccga agcaatcgaa
    14161 tttttaaacc gattgtccgg caaacaacat accgtcctga ctgccgtctg cattcattat
    14221 cgcggcaatg cggaaaaccg cgtccaaacc aaccgcgttg tttttaagcc cctgagttcg
    14281 gaagaaattt ccgcctatgt gcaaagcggc gaaccgatgg acaaagccgg tgcctacgcc
    14341 gtacaaggca taggcggcat ctttatccaa tctatcgaag gcagcttcag cggcattatg
    14401 ggactgcccg tttatgaaac cgtttcgatg ttgcaggatt tgggataccg ctcccccttg
    14461 tccgccctta aaccgtaaag tccgccgtga acagacaaac cgcttacctc cttacctctt
    14521 tcagcctgat cgcactgata atcctgtccc tttcctggga actgtggatt gcaccgttgc
    14581 gcccgggcgg ctcgtggctc gcgctcaaag ccctccccct ctgtctgccg ctttcaggta
    14641 tcttgaaaaa gaaaatctat acctaccaat acagctccat gctggttctg atttactttg
    14701 ccgaagccgt catgcgcctg ttcgacgcct atcccgcaga acagatttgc gccgcgcttt
    14761 ccgcagtatt cagcatcatc ttcttcatat cctgcctgtc gttcgtcaaa caatacaagg
    14821 aaacaaacaa tgcccgctga aacgaccgta tccggcgcgc gccccgccgc caaactgccg
    14881 atttacatcc tgccctgctt cctttggata ggcatcatcc cctttacctt cgcgctcagg
    14941 ctgcaaccgt cgcccgactt ttaccacgat gccgccgccg cagccggcct gattgtcctg
    15001 ttgttcctta cggcaggaaa aaagctgttt gatgtcaaaa tcccacccat cagcttcctt
    15061 ctgtttgcaa tggcggcgtt ttggtatctt caggcacgcc tgatgaacct gatttacccc
    15121 ggtatgaacg acatcgtctc ttggattttc atcttactcg ccgtcagcgc gtgggcctgc
    15181 cggagcttgg tcgcacacta cggacaagaa cgcatcgtga ccctgtttgc ctggtccctg
    15241 cttatcggct ccctgcttca atcctgtatc gtcgtcatcc agtttgccgg ctgggaagac
    15301 acccctctgt ttcaaaacat catcgtttac agcgggcaag gcgtaatcgg acacatcggg
    15361 cagcgcaaca acctcggaca ctacctcatg tggggcatac tcgcctccgc ctacctcaac
    15421 ggacaacgaa aaatccccgc cgccctcggc gtaatctgcc tgattatgca gaccgccgtt
    15481 ttaggtttgg tcaactcgcg caccatcttg acctacatag ccgccatcgc cctcatcctt
    15541 cccttctggt atttccgttc ggacaaatcc aacaggcgga cgatgctcgg catagccgca
    15601 gccgtactcc taaccgcgct gttccaattt tccatgaaca ccattctgga aacctttacc
    15661 ggcatccgct acgaaactgc cgtcgaacgc gtcgccaacg gcggtttcac agacttgccg
    15721 cgccaaatcg aatggaataa agcccttgcc gccttccagt ccgccccgat attcgggcac
    15781 ggctggaaca gttttgccca acaaaccttc ctcatcaatg ccgaacagca caacatatac
    15841 gacaacctcc tcagcaactt gttcacccat tcccacaaca tcgtcctcca actccttgca
    15901 gagatgggaa tcagcggcac gcttctagtt gccgcaaccc tgctgacggg cattgccggg
    15961 ctgctgaaac gccccctgac ccccgcatcg cttttcctga tctgcacgct tgccgtcagt
    16021 atgtgccaca gtatgctcga atatcctttg tggtatgtct atttcctcat ccctttcgga
    16081 ctgatgctct tcctgtcccc cgcagaggct tcagacggca tcgccttcaa aaaagccgcc
    16141 aatctcggca tactgaccgc ctccgccgcc atattcgcag gattgttgca cttggactgg
    16201 acatacaccc ggctggttaa cgccttttcc cccgcccctg acgacagtgc caaaaccctc
    16261 aaccggaaaa tcaacgagtt gcgctatatt tccgcaaaca gtccgatgct gtccttttat
    16321 gccgacttct ccctcgtaaa cttcgccctg ccggaatacc ccgaaaccca gacttgggcg
    16381 gaagaagcaa ccctcaaatc actaaaatac cgcccccact ccgccaccta ccgcatcgcc
    16441 ctctacctga tgcggcaagg caaagttgca gaagcaaaac aatggatgcg ggcgacacag
    16501 tcctattacc cctacctgat gccccgatac accgacgaaa tccgcaaact gcccgtatgg
    16561 gcaccgctgc tacccgaact gctcaaagac tgcaaagcct tcgccgccgc gcccggtcat
    16621 ccggaagcaa aaccctgcaa atgacccgcg ccggcggata cggataccgc ccgaaatgta
    16681 aagctccatg caagacattg caaaaaacag caaaccggta gggaaatacg ctatcaaaaa
    16741 acattgcagc cgtgttaaga taaaccgtca aacaatcttt tcacgccccg cccgaaacag
    16801 ggtcggggca tacccttacg aaaaggaaac accatgagcc gcgtattact cgtagatgac
    16861 gatgccctgc tgaccgaact gctgaccgaa tacctgagcg ccgaaggtct gaacgtccgc
    16921 agcgttcccg acggggaagc aggcgtacag gaaatcctga gcgggcagta cgatgtagtc
    16981 gtattggatt ccatgatgcc caaaatgaac ggcttggatg tcttgaaaaa cgtacgcgcc
    17041 cgaagcaccg tccccatcat catgctgacc gccaaaggcg acgacatcga ccgaatcatc
    17101 ggcttggaaa tgggcgcgga cgactatgtc cccaaaccct gcacaccacg cgaactcttg
    17161 gcacgcatca atgccatcct gcgccgcgca caacacagcg gcgaacagaa caacgcaccc
    17221 aacagcatct ccgtcagcga tgtcgtcctg taccccgcca aacgccaggc atccgtcaaa
    17281 gacatgccgc tcgaactgac cagcaccgaa ttcaacctgc tcgaagtcct gatgcgccat
    17341 gccggacagg tagtcagcaa agaaaccctg tccgtcgaag cactcgaccg caagctggca
    17401 aaattcgacc gcagtatcga cgtacacatc tccagcatcc gccacaagtt gggcgatgcc
    17461 tctctgattc aaaccgtacg cggcttgggc tacctgtttg tcaaaaactg aagcaacggg
    17521 caaatgaaac tgttccaacg catcttcgcc acattttgcg cagttatcgt ctgtgcaatc
    17581 tttgtggcga gtttttcttt ttggctggtg cagaacaccc ttgccgaaaa ccagttcaac
    17641 caacgccgca ccatcgaaac cactttgatg ggcagcatca tttccgcatt ccgggcacgc
    17701 ggggacgcgg gcgcgcgcga aatcctgacg gaatggaaag acagccccgt ctcatcgggc
    17761 gtgtacgtta tacagggcga cgagaaaaaa gatatcctga accggtatat cgacagctac
    17821 accatcgaac gcgcccggct tttcgccgcc ggacacccgc attccaacct cgtccatatc
    17881 gaatacgacc gcttcggcga agaatacctg ttcttcacca aagactggga caaactccaa
    17941 gcccgccgcc tgcccagccc cctgttgatc cccggtctgc cgctcgcccc gatttggcac
    18001 gaactcatca tattgtcctt catcatcgtc gtcggactgc tgatggcgta catcctcgcc
    18061 ggcaatatcg ccaaacccat cagaatctta ggcaacggca tggacagggt ggcaaacgga
    18121 gaacttgaaa cccgtatctc ccaacaggtc gacgaccgcg acgacgaatt gtcccatctt
    18181 gccatccaat tcgacaaaat ggtggaaaaa cttgaaaaac tcgttgccaa agaacgtcac
    18241 ctgctccatc acgtctccca tgaaatgcgt tctccccttg cgcgcatgca ggcaattgtc
    18301 ggactgattc aggcgcatcc ccaaaaacag gagcaatatc tcaaacggct ggaaggcgaa
    18361 ctgacccgca tggatacgct ggccggggaa ctgttaaccc tgtcccgtct cgaaacttcc
    18421 aatatggctt tggaaaaaga aagcctgaaa ctcctgccct tcctgggcaa cctggtagaa
    18481 gacaatcaaa gcattgccca gaaaaacgga caaacggtta ccctgtccgt cgacggaaaa
    18541 atccccgaaa acacaaccat ccttgccaac gaaagctacc tgtaccgcgc cttcgacaac
    18601 gtcatccgca acgccgtcaa ctacagtccc gaaggcagca ccatcctgat caacatcgga
    18661 caagaccaca aacactggat aatcgacgtt accgacaacg gccccggcgt ggacgaaatg
    18721 cagctcccgc acatcttcac cgctttctac cgtgcagact ccagtgcgaa caaacccgga
    18781 acaggactgg ggcttgcatt gacccaacat attattgaac agcactgcgg caaaatcatc
    18841 gccgaaaaca tcaaaccgaa cggtctgcgg atgcgcttta tcctgcccaa gaaaaaaacc
    18901 ggttccaaaa cagaaaaaag tgcgaactga ccataatacc gtctgaaccg gcttcagacg
    18961 gcattgcaca aacagttact ccaaaacaaa cacacagcgg gtgcatctcc aacaatcacg
    19021 cacataccgt ccgcaaagga atatatcatg tcggcacaaa ccgatccggg ctactttttc
    19081 atgcccaacc acattatcct gataggcgcg agcgaacgtc cgtacagcct gggcgaacgc
    19141 gtactcagca acctgctgag tacgcccttt caaggaaaaa tcacccccgt aaacccgcgc
    19201 caccacacca tagccgggct tcccgcctac accagcctca acaaaatccc cggcaatgca
    19261 gacctgatta ttgccgttac cctacccgac agttacgaca ccctcttcaa aacctgccgc
    19321 aaaaagcagc tccgacacat catcctcata caggactggg acagcctgtc tgccgcagaa
    19381 ctgcacaccg ccgaaactgc catccgcaaa caccacggca acggactcaa catcaccgcc
    19441 tgcaccaccg caggcatcca actgccctca ctcggactca acatcagtac ccaagacgga
    19501 tacgccgcag gccataccgc catactgacc ggcaatgccg ccgtcagccg ccaaatcgac
    19561 aacatcctga acaaactccg tcaaggcaca tcccgccaca tcagcctgca tcccggcatc
    19621 agccccatca cttcctcaga ctggctcaac cgcttcggcc acagcctgca caccaaaacc
    19681 gccgtcctac actacaaccc tgaagaggat cagcgcaaac tgttcagcgc aatccgccaa
    19741 tttacccgcc atacgccgct gattctccac atcacctgcc gcacgacaga aaccgaccgt
    19801 gccgtactgc actgcctcgc ccgacactgc aacttcctca tcagtttcaa cgccgacgac
    19861 ctcgaagccg cactgcgcgc ccaactgtcc gaccttcctc ccctgtcccg actcgacatc
    19921 ctgtccgaca cgcctgccga atggctgaac gcgcacgcgc caaaaaccct cgccctccac
    19981 tttcccaacc ttccccatca catccgcaac ggacacctga ccggcacacc cacaccctca
    20041 atctgccacg acatcgcctc acgtcagctt gcccgccccg acacccaagc cgtcctaacc
    20101 atcctcagtc cctccggaca cgaggattac aaaaaaacag cacgcgccct tatccgcctg
    20161 tccgaacaga ccgccaaacc cctgctcgtc agcagcccct tttcagacgg cataacacat
    20221 ttcgacaccc ccactcaggc aatccgcacc ctttcctacc gcaacaccgc cgccgccctg
    20281 aaacaggcac agctcgacat tgcaccgccg cagccatgcc gtctgaaaac accgcaaccc
    20341 caaaacatca aaaaagccct tgcagcggca aatccctccc tgctcgccga agccctgcac
    20401 ctccccccct accggcacac tacccataac gccgtccaat tccaattcgg cagccacccc
    20461 ctctatggcg acatcctgac cgcatgctgc aacggacaaa ccactgccgt actcccgccg
    20521 tttaccacgc tcgacagccg ccaccttgcc cgctttgccg aactcgacgg cacacaaacc
    20581 ctcgaccagt tcctgcacac actgaccgtc attcccgaat accgccaaca cattctcggc
    20641 atcaccctca acctcaacgg cggacaatac agcagcgatt tcatcttaaa gacacccgaa
    20701 acacacgaca cgcccaaacg caagaacaca ggcaaagccg cccaaaccct cgaacatgcc
    20761 gccgcaaaaa tgcagagtgc cgccgcatac ctgaaacaca aaaacccgac agccgccgaa
    20821 tttctccgcc acacaagcga agccgccgca gaactgctcg gcagcaaaac cgaaaccgga
    20881 gcagccgtac ccaacgtact tgccccctat cccgcagcac acctcaaaac actgtcccta
    20941 aaaaacaaca cgaccgttac cattaccccc cttttgcccg aagacgcaga agccaaacag
    21001 cagttcgtcc gcagcctcag ccccgaagca cggtacacac gcttcatgac ccacaccaac
    21061 gaactgcccg cagccacgtt ggcacgcctg tgcaaccccg attaccactg tgaagccgca
    21121 tggacggcaa gggatgccga cagcaacatc gtcgccgtcg tccgccacag ccgcctgaac
    21181 cgcaacgaat gcgaattcgg catcacactg gcggaacata tgcgcggcag cggactggca
    21241 cagaaaatga tggaactcat catccaaacc gccgcacagc aaggctaccg gactatgagt
    21301 gccgacattc tcaaaaccaa tactcccatg atcaaacttg ctgaaaaatc aggatttacc
    21361 ctcaaggaat cggacaccga aaaaaacctg taccgcgcat atctgaacct tgcggcagac
    21421 aaaacaacag aaaaaacaaa taaaaacttg cacaccgacc acaaaataac ctaaaatcgg
    21481 cagtttccat atatccgatt ttctcaaaag gactcaaaat ggtagttatc cgtttggcac
    21541 gcggcggctc gaaacaccgc cccttctaca acgtcatcgt tactgactca cgcagccgcc
    21601 gcgacggccg cttcatcgaa cgcgtaggct tctacaaccc cgtagccaac gaaaaacaag
    21661 agcgcgtccg cctcaatgca gaccgcctga accactggat tgcacaaggc gcgcaagtca
    21721 gcgactccgt tgcaaaactg attaaagaac aaaaagccgc ctaatccgcg tttgccgcca
    21781 tgacagacac tcaaaaccgg gtagccatgg gctacatcaa aggcgtattc ggcataaaag
    21841 gctggttgaa aattgccgcc aacaccgaat attccgacag ccttttggac taccccgagt
    21901 ggcatttggt caaggacggc aaaaccatca gcgttaccct tgaagccgga aaagtcgtca
    21961 acagcgaact ccaagtcaaa ttcgaaggca taaacgaccg cgacttggca ttctcattgc
    22021 gcggttacac catcgaaata ccccgtgaag cattcgcccc gacagaagaa gacgaatact
    22081 actggacaga cttggtcggc atgaccgtcg tcaacaaaga ccataccgtt ttaggcaagg
    22141 taagcaacct gatggaaacc ggcgcaaacg acgtattgat gattgacgga gaacacgggc
    22201 agattctgat tccgttcgtt tcccaatata tcgaaaccgt cgataccggc agcaagacca
    22261 ttactgccga ctggggtttg gactactgat gcttatccag gcagttacca ttttccccga
    22321 aatgttcgac agcattaccc gctacggcgt aacgggacgc gcgaacagac agggaatctg
    22381 gcagtttgaa gcagtcaatc cccgaaagtt tgccgacaac agattgggct acatcgacga
    22441 ccgcccgttc ggcggcggcc cgggaatgat tatgatggct ccgccgcttc atgcggcaat
    22501 agaacacgcc aaaacacaat cctcccaagc tgcaaaagtc atctacctca gcccccaagg
    22561 gaaaccgctg acacaccaaa aagcggtaga actggcagaa cttccgcatc tgattctgct
    22621 gtgcggacgg tatgagggca tagacgaaag gcttctgcaa agcagcgtcg atgaagaaat
    22681 cagcatcgga gacttcgttg tttccggcgg agagcttccc gccatgatgc tgatggatgc
    22741 ggtattgagg ctcgtacccg gcgtattggg cgatatgcag tctgccgaac aggattcgtt
    22801 ctcaagcggc attttggact gcccccacta caccaaaccc ttagaatttc aaggtatggc
    22861 tgttccggaa gtattgcgtt ccggcaatca tggcttgata gcggaatggc ggttggaaca
    22921 atcgctgcgc cgcaccttgg agcgcagacc cgatcttttg gaaaagcgcg ttttaatccc
    22981 aaaggaatcc cgcctcttag aaaccatccg gcaagagcaa cgggaaatcc aatcataatt
    23041 taggaaaaaa acaatgaacc tgattcaaca gctcgagcaa gaagaaattg cccgcctgaa
    23101 caaagaaatc cccgaattcg caccgggcga caccgtagtc gtatccgtac gcgtcgtgga
    23161 aggtacccgc agccgtctgc aagcctacga aggcgttgtc atttcacgcc gcaaccgtgg
    23221 tctgaacagc aacttcatcg tccgtaaaat ttccagcggc gaaggtgtgg aacgtacttt
    23281 ccaactgtac tcccctaccg ttgagaaaat cgaagtcaaa cgccgtggcg atgtccgccg
    23341 tgccaaactt tactatctgc gcggtctgac cggcaaagct gcacgcatta aagaaaaatt
    23401 gcctgcacgc aaaggttaat aagcgatttc ccccaatgcc gtctgaacct tcagacggca
    23461 tttcttattg ctgcgatgcc ggcaagtcaa cgatatgcct gcccctcatc caccttgatt
    23521 aacaatcact cccgcctatt caagcataat ttacagacca aacgttatac agtatcatat
    23581 cagccatata acgataaacg ctttaccgcc ttccctttca aaaccgcaaa tcatcatgac
    23641 accttccctt ttactatcag gattgacttt ccgcctcatc cttgccctga ttgccgtatc
    23701 ccttttatgg ggcgtttact tttgggcagt atccgcatga gcatcattgt cgaaaacctg
    23761 accgtcagct accgccgccg acctgccgtg caccatgtgg acattacttt tgaagaacat
    23821 agtatgtggg cggttttcgg tcccaacggc gcagggaaat ccacctttct caaatcctta
    23881 atgggattgc agcctatcga tacgggcagc atccggctgg acggattgac ccgtcagaac
    23941 attgcctacc ttccccagca gtccgacatc gaccgctcgc agcctatgac cgttttcgac
    24001 ttggcggcaa tggggctatg gtatgaaatc ggttttttca gaggaataaa tgccgttcaa
    24061 aaacaacgcg ttcacgaatc tttggaacgc gtcgggatgc ggcagtttgc cggccgccaa
    24121 atcgcccacc tctcaaacgg acaattccag cgtgtccttt ttgcccgaat gctggttcaa
    24181 aacgccaaat tcctacttct agacgaacct ttcaacgctg ttgatgcacg gacgacctac
    24241 gaacttctcg acgtattgca gaaatgccat tgcggcggac acgccatcat cgccgtactg
    24301 cacgattacg aacaagtccg tgcctacttt cccaataccc tgctgctcgc ccgcgaaaaa
    24361 attgcggcag gcgcaaccga gaccattctg acagaaccct acctcgccca agccaacgcc
    24421 aaaatgcagc aacaggaaag ccccgagtgg tgcgcctcat aaatgccgtc tgaaaccatg
    24481 tccccgtacc aaacactatg aacccctacg acctgcttat cacacccttt gcagaattcg
    24541 actttatgcg ctacgccctc gtatccgtct tctgcctgtc cctcagtgcc gcacccgtcg
    24601 gcgtattcct cgtcatgcgc cgtatgagcc tgataggcga cgcattgagc cacgctgtcc
    24661 tgcccggtgc cgccgtcggc tacatgtttg ccggcttgag cctgcccgcc atgggtttgg
    24721 gcggcgtagc cgcaggcatg ctgatggcac tgcttgccgg acttgttagc cgcttcacca
    24781 ccctgaaaga agatgccaac tttgccgcct tttatctcag cagcctcgcc ataggcgtag
    24841 tcctcgtcag caaaaacggc agcagcgtcg atctgctgca tctgcttttc ggctctgtac
    24901 ttgccgtcga tattcctgcc ctgcagctca tcgccgccgt atccaccctc acactgctta
    24961 cccttgccgt catctaccgc ccgctcgtac tcgaaagcat cgaccccctg tttctcaaat
    25021 ctgtcggcgg caaaggcggg ctttggcacg tcctctttct cgtcctggtc gtcatgaacc
    25081 tcgtatccgg ctttcaagcc ctcggcacac tcatgtccgt cggactcatg atgctgccag
    25141 ccattaccgc ccgcctgtgg gcgaagcaca tgggcgcact catcctccta tccgttctga
    25201 cagccctgct gtgcggcttg agcgggctgc tcatttccta ccacatcgaa atcccttccg
    25261 gccccgccat catcctctgt tgcagcgtcc tttatctctt ttccgtcata ctcggcaaag
    25321 aaggcggcat tctgaccaaa tggctcaaaa accaccgcca ccacaccacc tgaccccgca
    25381 agccgcttga acaaacaggc ggcttgtttt accataacag atgttacgtt atatcatagg
    25441 agaacagtta tgaaacaccc caaactcacc cttattgccg cattgctaac caccgccgca
    25501 actgccgccc ccctgcccgt cgtaaccagt ttcagcattt taggcgacgt agccaaacaa
    25561 atcggcggag agcgcgtatc catacaaagt ttggtcggag ccaaccaaga tacgcacgcc
    25621 tatcatatga ccagtggcga cattaaaaaa atccgcagtg caaaactcgt cctgctcaac
    25681 ggcttaggac ttgaagctgc cgatgtacaa cgtgccgtca aacagagcaa agtatcctat
    25741 gccgaagcga ccaaaggcat ccaacccctc aaagccgaag aagaaggcgg acaccatcac
    25801 gaccacgatc atgaccacga aggacaccac catgaccacg gcgaatatga cccccacgtc
    25861 tggaacgacc ccgtccttat gtccgcctat gcccaaaacg tcgccgaagc cctgataaag
    25921 gccgaccccg aaggcaaagt ttattatcaa caacgtttgg gcaactacca aatgcagctc
    25981 aaaaaactgc acagcgacgc acaagccgca tttaacgccg tccctgccgc caaacgcaaa
    26041 gtcctgaccg ggcacgatgc cttttcctac atgggcaaac gttaccatat cgaattcatc
    26101 gccccgcaag gtgtgagcag cgaagccgag ccttcagcca aacaagtcgc cgccatcatc
    26161 cgacaaatca aacgcgaagg catcaaagcc gtctttaccg aaaacatcaa ggacacccgt
    26221 atggttgacc gtatcgccaa agaaaccagt gtcaacgtca gcggcaaact gtattccgac
    26281 gcactcggca acgcgcccgc agacacctac atcggaatgt accgccacaa catcaaagcc
    26341 ttgaccaacg cgatgaagca ataaaaccgt ttgattggtt tgaatttgaa aaggcaaaag
    26401 gccgtctga
//
LOCUS       DAXISH010000023        25324 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.023, whole genome shotgun sequence.
ACCESSION   DAXISH010000023 DAXISH010000000
VERSION     DAXISH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 25324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25324
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.023"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..1609
                     /locus_tag="ACFOV4_000984"
     CDS             <1..1609
                     /locus_tag="ACFOV4_000984"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ArnT family glycosyltransferase"
                     /protein_id="HFC7619014.1"
                     /translation="PWLLLLMAFAWLWPGVFSHDLWNPAEPAVYTAVEALAGSPTPLV
                     AHLFGQTDFGIPPVYLWVAAAFKHLLSPWAADPYDAARFAGVFFAVVGLTSCGFAGFN
                     FLGRHHGRSVVLILIGCIGLIPVAHFLNPTAAAFAAAGLVLHGYSLARRRVIAASFLL
                     GTGWTLMSLAAAYPAAFALMLPLPVLMFFRPWQSRRLMLTAVASLAFALPLMTVYPLL
                     LAKTQPALFAQWLDDHVFGTFGGVRHVQTAFSLFYYLKNLLWFALPALPLAVWTVCRT
                     RLFSTDWGILGIVWMLAVLVLLAVNPQRFQDNLVWLLPPLALFGAAQLDSLRRGAAAF
                     VNWFGIMAFGLFAVFLWTGFFAMNYGWPAKLAERAAYFSPYYVPDIDPIPMAVAVLFT
                     PLWLWAITRKNIRGRQAVTNWAAGVTLTWALLMTLFLPWLDAAKSHAPVVRSMEASLS
                     PELKRELSDGIECIGIGGGDLHTRIVWTQYGTLPHRVGDVQCRYRIVLLPQNADAPQG
                     WQTVWQGARPRNKDSKFALIRKIGENI"
     gene            1726..2331
                     /locus_tag="ACFOV4_000985"
     CDS             1726..2331
                     /locus_tag="ACFOV4_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase N-terminal
                     domain-containing protein"
                     /protein_id="HFC7619015.1"
                     /translation="MMTLYSGITCPFSHRCRFVLYEKGMDFEIKDVDIYNKPEDLAVM
                     NPYNQVPVLVERDLVLHESNIINEYIDERFPHPQLMPGDPVMRGRGRLVLYRMEKELF
                     NHVQVLENPAATNKEQAKAREAIGNGLTMLAPSFSKSKYILGEDFSMIDVALAPLLWR
                     LDHYDVKLGKSAAPLLKYAERIFQREAFIEALTPAEKAMRK"
     gene            2403..2795
                     /locus_tag="ACFOV4_000986"
     CDS             2403..2795
                     /locus_tag="ACFOV4_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HFC7619016.1"
                     /translation="MPTSTKPYVLRALCEWCSDNSLTPHILVWVNEHTRVPMQYVRDN
                     EIMLNIGATATQNLQIDNDWISFSARFGGQAHDIWIPVGHVLSLFARETGEGMGFELE
                     EYRPDTPPENTSAETAPRPAKKGLKLVK"
     gene            complement(2824..2973)
                     /locus_tag="ACFOV4_000987"
     CDS             complement(2824..2973)
                     /locus_tag="ACFOV4_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619017.1"
                     /translation="MPSEARIAGSDSIFNVPISNRQGQHGFNTPKQVLPINGFRLRPI
                     GQNAV"
     gene            complement(2994..3440)
                     /locus_tag="ACFOV4_000988"
     CDS             complement(2994..3440)
                     /locus_tag="ACFOV4_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFC7619018.1"
                     /translation="MSLKIRLTEDMKTAMRAKDQVSLGTIRLINAAVKQFEVDERTEA
                     DDAKITAILTKMVKQRKDSVKIYTEAGRQDLADKENAEIEVLHRYLPQMLSAGEIRTA
                     VDAAVAETGAAGMADMGKVMGVLKTRLAGKADMGEVNKILKAVLTA"
     gene            complement(3572..3784)
                     /gene="rpsU"
                     /locus_tag="ACFOV4_000989"
     CDS             complement(3572..3784)
                     /gene="rpsU"
                     /locus_tag="ACFOV4_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011484193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFC7619019.1"
                     /translation="MPAIRVKENEPFEVAMRRFKRAVEKTGLLTELRAREAYEKPTTE
                     RKRKKAAAVKRLQKRLRSQQLPPKMY"
     gene            complement(4073..5920)
                     /gene="ltgA"
                     /locus_tag="ACFOV4_000990"
     CDS             complement(4073..5920)
                     /gene="ltgA"
                     /locus_tag="ACFOV4_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase LtgA"
                     /protein_id="HFC7619020.1"
                     /translation="MYLPSMKHSLPLLAALVLAACSSTHAPSSKTLADNIETAGLSAS
                     VPTRPAEPEGKTLADYSSYPSALDAVKQKNDAAVAAYLENAGDSAMAENVRNEWLKSL
                     GARRQWTLFAQEYAKLKPEGRAQEVECYADSSRNDYTRAAELVKNTGKLPSGCTKLLE
                     QAAASGLLDGNDAWRRVRGLLAGRQTTDARNLAAALGSPFDGGTQGSREYALLNVIGK
                     EARKSPNAAALLSEMESGLSLEQRSFAWGVLGHYQSQNLNVPAALDYYGKVADRRQLT
                     DDQIEWYARAALRARRWDELASVISHMPEKLQKSPTWLYWLARSRAATGNTQEAEKLY
                     KQAVATGRNFYAVLAGEELGRKIDTRNNVPDAGKNSVLRMAEDGAIKRALVLFQNSRT
                     AGDAKMRRQAQAEWRFATRGFDEDKLLTAAQTAFDHGFYDMAVNSAERTDRKLNYTLR
                     YISPFKDTVIRHAQNVNVDPAWVYGLIRQESRFVIGAQSHVGAQGLMQVMPATAREIA
                     GKIGMDAAQFYTADGNIRMGTWYMADTKRRLQNNEVLATAGYNAGPGRARRWQADTPL
                     EGAVYAETIPFSETRDYVKKVMTNAAYYAALFGAPHIPLKQRMGIVPAR"
     gene            6451..7188
                     /locus_tag="ACFOV4_000991"
     CDS             6451..7188
                     /locus_tag="ACFOV4_000991"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFC7619021.1"
                     /translation="MIILDKVSKHYQTRDKTRFAAVEPTSLEIRDGEIFGLMGYSGAG
                     KSTLLRLINLLERPDSGKVNVCGQELTALDAAALRQARQNIGMVFQQFNLLNNRTVAG
                     NVAFPLEIAGWPSEKIKTRVAECLEIVGLTERAGHYPAQLSGGQKQRVGIARALAPKP
                     QVILADEPTSALDPATTRSVLECLEDINKRFNVTIVIVTHEMSVIRRLCDRAALLDKG
                     KVVEIVEVRGNQIHARSDIGRELIRED"
     gene            7190..7876
                     /locus_tag="ACFOV4_000992"
     CDS             7190..7876
                     /locus_tag="ACFOV4_000992"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFC7619022.1"
                     /translation="MADLTFQQAVSNIIGMKGEIVRALGETFVMVGLSTTFAVVFGTL
                     LGVLLFVTSSRQLHYNKAVNFLLDNLVNLMRAFPFVILMIAMIPATRAIVGSTIGPVA
                     ASLVLSVSGLFYFARLVEQNLREVPKGVIEAAAAMGAPPVAIIRKVLLNEARAGMVSS
                     ITVLAIGLLSYSAAAGMIGGGGLGDLAIRYGYYRYQTEVIVFIVALLVLLVILIQSTG
                     NALARKLDKR"
     gene            8035..8898
                     /locus_tag="ACFOV4_000993"
     CDS             8035..8898
                     /locus_tag="ACFOV4_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFC7619023.1"
                     /translation="MKTFFKTLSAAALALILAACGGQKDSAPAASASAAADNGAAKKE
                     IVFGTTVGDFGDMVKEQIQPELEKKGYTVKLVEFTDYVRPNLALAEGELDINVFQHKP
                     YLDDFKKEHNLDITEVFQVPTAPLGLYPGKLKSLEEVKDGSTVSAPNDPSNFARVLVM
                     LDELGWIKLKDGINPLTASKADIAENLKNIKIVELEAAQLPRSRADVDFAVVNGNYAI
                     SSGMKLTEALFQEPSFAYVNWSAVKTADKDSQWLKDVTEAYNSDAFKAYAHKRFEGYK
                     SPAAWNEGAAK"
     gene            complement(8961..9530)
                     /locus_tag="ACFOV4_000994"
     CDS             complement(8961..9530)
                     /locus_tag="ACFOV4_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFC7619024.1"
                     /translation="MVRRLIIGISGASGFQYGVKALELLRAQDIETHLVVSKGAEMAR
                     ASETAYARDEVYALADFVHPIGNIGACIASGTFKTDGMLVAPCSMRTLASVAHGFGDN
                     LLTRAADVVLKERRRLVLMVRETPLNLAHLDNMKRVTEMGGVVFPPVPAMYRKPQTAD
                     DIVAHSVAHALSLFGIDTPDSTEWQGMAD"
     gene            9688..10548
                     /locus_tag="ACFOV4_000995"
     CDS             9688..10548
                     /locus_tag="ACFOV4_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFC7619025.1"
                     /translation="MAKVKGGLGRGLDSLLANGADNSSGDRLTTVAVKDIRPGRYQAR
                     VQIDDEALQELADSIKAQGVIQPVIVREHGLSRYELIAGERRWRAAQIAGLTEIPAVI
                     KTISDETALAMGLIENLQRENLNPIEEAQGLKRLADEFGLTHETIAQAVGKSRSAISN
                     SLRLLSLPEPVQEMLYQRRLEMGHARALLTLPVVEQLELAQKAVKNGWSVREVERRSQ
                     AALQNKRPEPKKTAAADIGRLNDLLTEKLGVNAEIKTANHKKGRIILHFDTPETFDHI
                     LKQLGIDYRP"
     gene            10684..11022
                     /locus_tag="ACFOV4_000996"
     CDS             10684..11022
                     /locus_tag="ACFOV4_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619026.1"
                     /translation="MNTRIIVSAAFVALALAGCGSINNVTVSDQKLQERAAFALGVSP
                     NAVKISNRNNEGIRINFTATVGKRVSQCYVTSVISTIGVTTSDAICLGGGTHKGKSQC
                     NALLKAAGRC"
     gene            11390..11743
                     /locus_tag="ACFOV4_000997"
     CDS             11390..11743
                     /locus_tag="ACFOV4_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HFC7619027.1"
                     /translation="MKQIIILQSAVLSICAAVAFAVWGFAGFLSAVGGGLSYLLPTFV
                     AVLLLKLFRGNPFLQSRMFVFGEILKVVLSLLSMLAVFAIWHQSLVFAPFLMGLLGVS
                     HLVFLVLLRVKDYGR"
     gene            11733..12599
                     /gene="atpB"
                     /locus_tag="ACFOV4_000998"
     CDS             11733..12599
                     /gene="atpB"
                     /locus_tag="ACFOV4_000998"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004464456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFC7619028.1"
                     /translation="MAGETITAADYIKHHLQSLTSLSDVTQGQGLKNIADFSFINLDA
                     VFFAVLLGVIGSFLLWRGAKKATAGVPGRFQAAVEILFEFVDDMCKSIIHNEKSRKAV
                     APLGLTLFVWIFLMNAMDMLPVDLLPMVWQGITGNHHALLRVVPTADLNTTLALAVGV
                     LLICIYYNIKIKGLGGWFHELFSAPFGAKLAPANFLLNLVEFLSKTVSHGMRLFGNMY
                     AGELVFLLIALLGGAWAASGSVEVMDPILFVFHIIAGLAWAIFHILVITLQAFIFMAL
                     AFVYIGQAHDAH"
     gene            12656..12892
                     /gene="atpE"
                     /locus_tag="ACFOV4_000999"
     CDS             12656..12892
                     /gene="atpE"
                     /locus_tag="ACFOV4_000999"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HFC7619029.1"
                     /translation="MGLIAIACGLIVALGALGASIGIAMVGSKYLESSARQPELIGPL
                     QTKLFLIAGLIDAAFLIGVAIALLFAFVNPFAGA"
     gene            12963..13433
                     /locus_tag="ACFOV4_001000"
     CDS             12963..13433
                     /locus_tag="ACFOV4_001000"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFC7619030.1"
                     /translation="MNINATLFAQIIVFFGLVWFTMKFVWPPIAKALDERAAKVAEGL
                     AAAERGKSDFEQAEKKVAELLAEGRNQVSEMVANAEKRAAKIVEEAKEQASSEAARIA
                     AQAKADVEQELFRARESLREQVAVLAVKGAESILRSEVDASKHAKLLDTLKQEL"
     gene            13438..13971
                     /locus_tag="ACFOV4_001001"
     CDS             13438..13971
                     /locus_tag="ACFOV4_001001"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFC7619031.1"
                     /translation="MAEFATIARPYAKALFGLAQEKNQIESWLGGLEKLAAVVQEGKV
                     ASLIDRPETNASEKADILIDLVGLKDKELKNFVIVLAGQKRLSILPEVYAQYQDLTLS
                     FNHIKSAIIYSAYPLTDKQVGELAQMLNKRFDSELKISVEIEPELIGGIKVEVGDQVL
                     DLSVQGKLSALYTTMTN"
     gene            13982..15529
                     /gene="atpA"
                     /locus_tag="ACFOV4_001002"
     CDS             13982..15529
                     /gene="atpA"
                     /locus_tag="ACFOV4_001002"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFC7619032.1"
                     /translation="MQLNPAEISDLIKAKIENLSVNAEVRTRGTVISVTDGIVRIHGL
                     SDAMQGEMLEFPGNTFGLAMNLERDSVGAVVLGEYEHIKEGDTVTCTGRILEVPVGRE
                     LVGRVVDALGRPIDGKGPINTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVG
                     RGQRELIIGDRQTGKTAVALDAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAM
                     EHTIVVAATASEAAALQYIAPYSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLL
                     LRRPPGREAYPGDVFYLHSRLLERAARVSENEVEKLTNGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGG
                     IRLALAQYRELAAFSQFASDLDEATRKQLEHGEVVTELMKQKQFSTLNTAEMALTLWA
                     INNGSYSDVPVAKALAFESEFLSFVRTQHPEVLEAVNASGAMSDESEKTLEAAMKSFK
                     SSYAYQA"
     gene            15554..16429
                     /gene="atpG"
                     /locus_tag="ACFOV4_001003"
     CDS             15554..16429
                     /gene="atpG"
                     /locus_tag="ACFOV4_001003"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003705028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFC7619033.1"
                     /translation="MAVGKEILTKIRSVQNTQKITKAMQMVSTSKMRKTQERMRLARP
                     YAEKVRMVMSHLAQTNTDHGIPLLESHREIRRVGFILITSDKGLCGGLNANVLKKFLA
                     QVQEYRNQGIEEEIVCLGSKGLMACQSIGLNVVASAVNLGDTPKMEMLLGPLTELFQR
                     YEKHEIDRIHLVYSGFVNTMRQEPRMEVLLPIGENVIGDSAPKSPFSWEYRYEPTALA
                     VLEYLVRRYLESVVYQALSDNMASEQAARMVAMKAATDNAGNAIKELRLVYNKSRQAA
                     ITTELSEIVAGAAAV"
     gene            16467..17864
                     /gene="atpD"
                     /locus_tag="ACFOV4_001004"
     CDS             16467..17864
                     /gene="atpD"
                     /locus_tag="ACFOV4_001004"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFC7619034.1"
                     /translation="MSQGKIVQIIGAVVDVEFPRDMIPRVYDALKLDENGLTLEVQQL
                     LGDGVVRTIAMGSSDGLKRGMTVSNTGAPITVPVGKGTLGRIVDVLGTPVDEAGPIDT
                     DKSRAIHQAAPKFDELSSTTELLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMME
                     LINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRV
                     ALTGLTMAEYFRDEKDENGKGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTL
                     AEEMGRLQERITSTQTGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLG
                     IYPAVDPLDSTSRQLDPMVLGQEHYDVARGVQSTLQKYKELRDIIAILGMDELSDEDK
                     LTVMRARKIQRFLSQPFHVAEVFTGSPGKYVALRDTIAGFKAILNGEYDHLPEQAFYM
                     VGSIEEAVEKAKTLN"
     gene            17875..18297
                     /locus_tag="ACFOV4_001005"
     CDS             17875..18297
                     /locus_tag="ACFOV4_001005"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFC7619035.1"
                     /translation="MSIMQVEVVSSEQKIYSGEATFIVVPTVQGELGIYPRHEPIMSL
                     VRPGALRLTVPGEDKEVLVAVSGGVLEVQPDKVTVLADVAVRSAEMDQARAEEAKKAA
                     EAGISQAKDDKALAEAHKALAAAIAQLKTLDYIRSHKK"
     gene            18702..19607
                     /gene="glyQ"
                     /locus_tag="ACFOV4_001006"
     CDS             18702..19607
                     /gene="glyQ"
                     /locus_tag="ACFOV4_001006"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFC7619036.1"
                     /translation="MLTFQQIIFKLQTFWADKGCTVIQPFDMEVGAGTSHPATCLRAL
                     GPEPWFAAYVQPSRRPKDGRYGDNPNRLQHYYQFQVALKPAPANIQDLYLDSLRELGI
                     DPKVHDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCTPVLGEITY
                     GIERLAMYLQGVENVYDLVWAKTPDGNTVSYGDVYHQNEVEQSTYNFEYSDADWLLRQ
                     FNDYEAQAKRLLAEENAALALPAYELVLKAGHTFNLLDARGAISVTERATYIGRIRAL
                     SRAVAQKYVESREKLGFPLMKANAA"
     gene            19684..20094
                     /locus_tag="ACFOV4_001007"
     CDS             19684..20094
                     /locus_tag="ACFOV4_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding protein YggL"
                     /protein_id="HFC7619037.1"
                     /translation="MPVYFRTPSRKRLHKMNRRQHKKLHLGEFQTLIFGVQGSLHQAE
                     DDAEAFDRFMDELIAYLEVNDFGMAGGGDCGDFSCLFQKSGARSLGETEKKAIISWLA
                     GREDVATLHTTPLVDGFYGDDGWENYSETYKQAD"
     gene            20115..22178
                     /gene="glyS"
                     /locus_tag="ACFOV4_001008"
     CDS             20115..22178
                     /gene="glyS"
                     /locus_tag="ACFOV4_001008"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFC7619038.1"
                     /translation="MMTQTLLIELLTEELPPKALNNLGNHFAAAVAEGLEKAQLVDGA
                     AEFTAYASPRRLAVQVKNVKAVQADQKIVKKGPAVANAMKDGAPTKALEGFARGAGAK
                     IEDLTIVHDGKQDVYAYEYVQTGKPLGELLEDIINQAVKKLPIPKVMRWGSSTFTFVR
                     PVHGLIVLHGGDIVNVSVLGLQSSNQTLGHRFLSNGEITIENADSYAEQMRGQGKVVA
                     SFAERKAAIQTALEGQARSLNAAVAADEALLDEVTALVEWPVVLEAGFEEHFLAVPQE
                     CLILTMQQNQKYFPLLDQNGKLMNRFLLVSNLQTEDPSHIIRGNERVLRARLSDAEFF
                     YKQDQKATLESRLPKLSSVVYHNKIGSQAERIERLQSIAAHIAKALGADAAAAERAAR
                     LAKADLVTEMVGEFPELQGTMGKYYARLDGETEEIAEAIEQHYQPRFAGDKLPESKIA
                     AAVALADKLETLVGIWGIGLIPTGDKDPYALRRAALGILRMLMQYGLDVNELIQTAFD
                     SFPKGLLNEKTPSETADFMQARLAVLLQNDYPQDIVAAVLAKQPRRLDDLTAKLQAVA
                     AFKQLPEAAALAAANKRVQNLLKKADAALGAVNESLLQQDEEKALFAAAQGLQPKIAA
                     AVAEGNFQTALSELASVKPQVDAFFDGVMVMAEDAAVKQNRLNLLNRLAEQMNAVADI
                     ALLGE"
     gene            22195..23241
                     /locus_tag="ACFOV4_001009"
     CDS             22195..23241
                     /locus_tag="ACFOV4_001009"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFC7619039.1"
                     /translation="MPSEAFRRHRAYRENKLQPLVSVLICAYNVEKYFAQSLAAVVNQ
                     TWCNLDILIVDDGSTDGTLAIAKDFQKRDSRIKILAQAQNSGLIPSLNIGLDELAKSG
                     GGEYIARTDADDIAAPDWIEKIVGEMEKDRSIIAMGAWLEVLSEEKDGNRLARHHRHG
                     KIWKKPTRHEDIADFFPFGNPIHNNTMIMRRSVIDGGLRYNTERDWAEDYQFWYDVSK
                     LGRLAYYPEALVKYRLHANQVSSKYSVRQHEIAQGIQKTARNDFLQSMGFKTRFDSLE
                     YRQIKAVAYELLEKHLPEEDFERARRFLYQCFKRTDTLPAGAWLDFAADGRMRRLFTL
                     RQYFGILHRLLKNR"
     gene            23283..24110
                     /locus_tag="ACFOV4_001010"
     CDS             23283..24110
                     /locus_tag="ACFOV4_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 25 protein"
                     /protein_id="HFC7619040.1"
                     /translation="MQNHVISLASAAERRAHIAATFGARGIPFQFFDALMPSERLEQA
                     MAELVPGLSAHPYLSGVEKACFMSHAVLWKQALDEGLPYIAVFEDDVLLGEGAEKFLA
                     EDAWLKERFDPDSAFIVRLETMFMHVLTSPSGVADYCGRAFPLLESEHWGTAGYIISK
                     KAIRFFLQHFVMLQPEQIKPIDLMMFSDFFDKEGMPVYQVSPALCAQELHYAKFHDQN
                     SALGSLIEHDRLLNRKQQRRDSPANTFKRRLIRALTKISREREKRRQRREQFIVPFQ"
     gene            24122..24217
                     /locus_tag="ACFOV4_001011"
                     /pseudo
     CDS             24122..24217
                     /locus_tag="ACFOV4_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
     gene            24259..25101
                     /locus_tag="ACFOV4_001012"
     CDS             24259..25101
                     /locus_tag="ACFOV4_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 25 protein"
                     /protein_id="HFC7619041.1"
                     /translation="MQNHVISLASAAERRAHIADTFGRHDIPFQFFDALMPSEELNRV
                     MAELVPGLAKQHLLSEVEKACFMSHAVLWKQALDEGLPYVAVFEDDVLLGKDAEKFLA
                     EDTWLEERFDKDSAFIVRLETMFAKVIVRPDKVLNYENRSFPLLESEHWGTAGYIISR
                     EAMRFFLERFAVLPAEWIKAVDWMMFTYFFDKEGMPVYQVNPALCTQELHYAKFLSKN
                     SMLGSDLEKDREQERRHRRSLKVMFDLKRALGKFGREKKKRMERQRQAELEKAYGRRV
                     ISFK"
BASE COUNT         5993 a         6664 c         6693 g         5974 t
ORIGIN      
        1 gccgtggctg ctgctgttga tggcgtttgc ctggttgtgg cccggcgtgt tttcccacga
       61 tttgtggaat cctgccgaac ctgccgtcta taccgccgtc gaagcactgg caggcagccc
      121 cacccctttg gttgcccatc tgttcggtca aaccgatttc ggcataccgc ccgtgtatct
      181 ttgggttgcc gccgcgttca aacatttgct gtcgccgtgg gcagccgacc cgtatgatgc
      241 cgcacgcttt gccggcgtgt ttttcgccgt tgtcggactg acttcctgcg gctttgccgg
      301 tttcaacttt ttgggcagac accacgggcg cagcgtcgtc ctgattctca tcggctgtat
      361 cgggctgatt ccagttgccc atttcctcaa ccccactgcc gccgcctttg ccgccgccgg
      421 actggtgctg cacggttatt ctttggctcg ccggcgcgtg attgccgcct cttttctgct
      481 cggtacgggc tggacgctga tgtcgttggc agcagcttat ccggcagcat ttgccctgat
      541 gctgcccttg cccgtactga tgtttttccg tccgtggcaa agcaggcgtt tgatgttgac
      601 ggcagtcgcc tcacttgcct ttgccctgcc gcttatgacc gtttacccgc tgctcttggc
      661 aaaaacgcag cccgcgctgt tcgcgcaatg gctcgacgat cacgttttcg gtacgttcgg
      721 cggcgtgcgg cacgttcaga cggcattcag tttgttttac tatctgaaaa acctgctttg
      781 gtttgcattg cctgcgctgc cgctggcggt ttggacggtt tgccgcacgc gcctgttttc
      841 gaccgactgg gggattttgg gcattgtgtg gatgcttgcc gttttggtgc tgcttgccgt
      901 caatccgcag cgttttcagg ataacctcgt ctggctgctt ccgccgcttg ccctgttcgg
      961 cgcggcgcaa ctggacagcc tgaggcgcgg cgcggcggcg tttgtcaact ggttcggcat
     1021 tatggcgttc ggactgtttg ccgtgttcct gtggacgggc tttttcgcca tgaattacgg
     1081 ctggcccgcc aagcttgccg aacgcgccgc ctacttcagc ccgtattacg ttcccgacat
     1141 cgatcccatt ccgatggcgg ttgccgtact gttcacaccc ttgtggctgt gggcgattac
     1201 ccgcaaaaac atacgcggca ggcaggcggt taccaactgg gcggcaggcg ttaccctgac
     1261 ctgggctttg ctgatgacgc tgttcctgcc gtggctggac gcggcgaaaa gccacgcgcc
     1321 ggtcgtccgg agtatggagg catcgctttc cccggaatta aaacgggagc tttcagacgg
     1381 catcgagtgt atcggcatag gcggcggcga cctgcacacg cggattgttt ggacgcagta
     1441 cggcacattg ccgcaccgcg tcggcgatgt acaatgccgc taccgcatcg tcctcctgcc
     1501 ccaaaatgcg gatgcgccgc aaggctggca gacggtttgg cagggtgcgc gtccgcgcaa
     1561 caaagacagt aagttcgcac tgatacggaa aatcggggaa aatatataaa aaacaacaga
     1621 ttgagccgaa tttctggatt aagtgccgga aatcgcgtat aattgcgcga ttaaaccttt
     1681 ataaatcagc cgttttacag gcatcacaca ggagcgacaa ttattatgat gaccctctat
     1741 tccggcatta cctgcccctt cagccaccgc tgccgcttcg ttttgtacga aaaaggcatg
     1801 gattttgaaa tcaaagacgt cgatatttac aacaagcccg aagacctcgc cgtcatgaac
     1861 ccgtataacc aagttcccgt gctggtcgag cgcgatttgg tgctgcacga gtccaacatc
     1921 atcaacgaat acatcgacga acgcttcccc catccgcagc ttatgcccgg tgatcccgtt
     1981 atgcgcggca ggggccggct ggtgctgtac cgtatggaaa aagaattgtt caaccacgtc
     2041 caagttttgg aaaaccccgc cgccaccaac aaggaacagg caaaagcgcg cgaagccatc
     2101 ggcaacggtc tgaccatgct tgccccttcg ttcagcaaaa gcaaatacat cctcggcgaa
     2161 gatttttcta tgattgatgt cgcccttgct ccgctgctgt ggcggctcga ccactacgat
     2221 gtcaaactgg gcaaaagtgc cgcgccgctg ctcaaatacg ccgagcgcat cttccagcgc
     2281 gaagccttta tcgaagcact gacacccgcc gaaaaagcca tgcgcaaata agtccgaaat
     2341 gcttgcaaaa cccaccgttt tgcaggcatt ttcctatttt ggcgtacaac acggaaccca
     2401 tcatgcccac ctcaaccaaa ccctacgtcc tccgcgctct ctgcgaatgg tgcagcgaca
     2461 acagcctcac accgcacatc cttgtttggg tcaacgaaca cacgcgcgtc cccatgcagt
     2521 atgtccgcga caatgaaatt atgctcaaca tcggtgcgac cgccacgcaa aaccttcaaa
     2581 tcgacaacga ttggatcagc ttttccgccc gtttcggcgg acaggcgcac gacatatgga
     2641 tacctgtcgg acacgtcctt agccttttcg cacgggagac cggcgaaggt atggggtttg
     2701 aattggagga gtaccgcccc gacacgccgc ctgaaaacac ctctgccgaa accgcgcccc
     2761 gacccgccaa aaaaggcttg aaattggtca aataaatcta tgccgtctga acggaatcgt
     2821 gtttcagacg gcattttgtc cgatggggcg caaacggaat ccgtttatcg gcaaaacctg
     2881 tttcggcgta ttgaaaccgt gttgcccctg ccgattcgat attgggacat tgaaaatgct
     2941 gtctgaacct gcgatacggg cttcagacgg cattttgtcc gatattcggg caatcaggcg
     3001 gtcagcacgg ctttcaggat tttgttgact tcgcccatat cggctttgcc ggcaagtcgg
     3061 gttttcaata cgcccatcac tttgcccata tccgccatac ctgccgcgcc ggtttcggca
     3121 acggcggcat cgaccgcagt acggatttcg ccggcggaga gcatttgcgg caggtagcgg
     3181 tgcagtacct cgatttcggc gttttctttg tctgccaaat cctgacggcc ggcttcagtg
     3241 tagattttca cgctgtcttt gcgctgtttg accattttgg tcaggatggc ggtgattttg
     3301 gcatcgtcgg cttcggtgcg ttcgtccact tcaaactgtt tgacggcggc gttgatgagg
     3361 cggatggtgc cgagggaaac ttggtctttg gcgcgcatcg cggttttcat gtcttcggta
     3421 aggcggattt tcaggctcat aatgttctcg ctgggatgtc ggatggaaac ggcgggtttc
     3481 gatgccgtct gaaaagcaaa acacaccgca gagcaggtct tgcggtgtgt cctcatatca
     3541 cagggctgac ctgtaatctg tacttgaacg tttagtacat tttgggcggc agttgttggc
     3601 tgcgcaggcg tttttgcagg cgttttacgg ctgccgcttt tttgcgtttg cgttcggtag
     3661 tcggtttttc gtaggcttcg cgggcgcgca gctcggtcag caggccggtt ttttctacgg
     3721 cgcgtttgaa acggcgcata gcgacttcaa agggttcgtt ttcttttacg cggattgcag
     3781 gcattttatt tcctttaata aattctgttg ttgcatctgc ccatcatatc ggtggaaagg
     3841 gtagggcaga cggtgttgaa ggtttaccgt atcgctgtgc cttgcggcgg cgggatacgc
     3901 gccgtgacgg aaacatcacc tcctaacggg tcggcttgtg ccgtgtcaag ctgcttgaaa
     3961 aagcaggaaa aacaattttc gaattgtctt atatttatgg ttcgccgtca atgccgttcg
     4021 ggataaaaat gccgtctgaa agaccgggcg ggtttcagac ggcatcggta cgtcagcgtg
     4081 caggaacaat gcccatacgc tgtttgagcg ggatgtgcgg cgcgccgaag agggcggcgt
     4141 agtaggcggc attggtcatc acttttttga catagtcgcg cgtttcggaa aacgggatgg
     4201 tttcggcata taccgcgcct tcgaggggcg tgtccgcctg ccatcggcgc gccctgccgg
     4261 gaccggcgtt atagcctgcg gtggcgagga cttcgttgtt ttgcaggcgg cgtttggtgt
     4321 ccgccatata ccacgtcccc atacggatat tgccgtcggc ggtgtaaaat tgtgcggcat
     4381 ccataccgat tttgccggcg atttcgcgcg cggtggcagg cataacctgc atcagcccct
     4441 gcgcgcctac gtgggattgc gcgcctataa cgaagcggct ttcctgacga atcagaccgt
     4501 aaacccaagc cggatcgaca ttaacatttt gcgcgtggcg gattaccgtg tctttaaacg
     4561 gcgaaatata gcgcaaggtg tagttgagtt tgcggtcggt gcgttccgcg ctgttgaccg
     4621 ccatatcgta aaaaccgtgg tcgaacgcgg tttgcgcggc ggtcagcagc ttgtcttcgt
     4681 caaagccgcg tgtggcaaaa cgccattccg cctgagcctg acggcgcatt ttcgcatcgc
     4741 cggcggttcg gctgttttgg aacagtacca gcgcgcgctt aatcgcgccg tcttccgcca
     4801 tacggaggac gctgtttttg ccggcatcgg gaacattgtt gcgcgtatcg attttgcgcc
     4861 ccaactcttc ccctgccagt acggcataaa aattcctgcc cgtcgctacc gcctgtttgt
     4921 agagtttttc cgcctcttgc gtgttgcccg ttgcggcgcg gctgcgtgcc agccagtaga
     4981 gccaggtcgg gcttttttgc agtttttcgg gcatatgcga gattacggaa gccagctcgt
     5041 cccaacgtcg ggcgcgcaag gcggcgcggg cgtaccactc gatttggtcg tcggtcagtt
     5101 ggcggcggtc ggcaaccttg ccgtaatagt ccaaggcggc aggcacattg aggttttgcg
     5161 actgataatg ccccaatacg ccccacgcga aactgcgttg ttcgaggctt aaaccgcttt
     5221 ccatttcgga cagcagggcg gcggcattcg gcgatttgcg tgcttctttg ccgatgacgt
     5281 tcaacagggc atattcgcgc gaaccttgtg taccgccgtc aaacgggctg cccaatgcgg
     5341 cggcaaggtt gcgtgcgtct gtggtttggc ggccggccag cagtccgcgc acgcgcctcc
     5401 aggcgtcgtt gccgtccaac aagccggatg cggctgcctg ttccaacagt ttggtgcagc
     5461 ccgaaggcag tttgcccgta tttttgacca gttcggcggc acgcgtatag tcgttgcggc
     5521 tcgaatcggc gtagcattcg acttcttggg cgcgcccttc aggtttgagt ttggcatatt
     5581 cctgtgcaaa cagcgtccac tgtctgcgtg cgcccaaaga cttcagccac tcgttgcgga
     5641 cattttccgc catcgcgctg tcgccggcgt tttccaaata ggcggcgacg gcggcatcgt
     5701 ttttctgttt cactgcatcc agtgcggaag ggtagctgct gtaatctgcc agcgtttttc
     5761 cttcgggttc ggcagggcgg gtgggaacgc ttgccgaaag accggcagtt tctatattgt
     5821 ctgccagggt cttgctgctg ggcgcgtgtg tcgaagaaca cgcggcaagc accagggccg
     5881 ccagcagcgg cagggaatgc ttcatagagg gtaggtacat cggatttcct taagaatcgg
     5941 aaccctgaac ggtcagggtt ggaaaagaca aaatgccgtc tgaacaggcg tttgcccgaa
     6001 ttatatgccg aaactgcacc gcctttggaa tgtttccgac ataatttata gtggattaaa
     6061 tttaaaccag tacggcgttg cctcgcctta gctcaaagag aacgattctc taaggtgctg
     6121 aagcaccaag tggatcggtt ccgtactatt tgtactgtct gcggcttcgt cgccttgtcc
     6181 tgatttttgt taatccacta tatgtttttc aattatttgc cgttttggtg cgaaccgctg
     6241 cctttgcccg tttcagacgg cattgtccga aatggttgcc cgcttcctgc tttattgaca
     6301 aaaaaatgct ttcccgataa tatcctacga aaattaacct gccgatttga cacagcttgc
     6361 gggcataaca gctaaagcgt tccgacaatt tcagctttat cttccgcgcc cgttgtgtcc
     6421 gacatcgggc tttgttgtat ggaaaagaca atgattattt tggacaaggt ttccaagcat
     6481 taccaaacgc gcgacaagac ccgttttgcc gccgtcgagc cgaccagcct cgaaatccgc
     6541 gacggcgaaa tcttcgggct gatgggttat tcgggtgcag gcaaatccac cctgttgcgc
     6601 ctgattaacc tgttggaacg ccccgacagc ggcaaggtca acgtctgcgg acaagagctg
     6661 accgcgcttg atgccgccgc attgcgtcag gcgcggcaga atatcggcat ggtatttcaa
     6721 cagttcaacc tgttgaacaa ccgcaccgtc gccggcaacg tcgccttccc attggaaatc
     6781 gccggatggc cgtctgaaaa aatcaaaacg cgcgttgccg aatgcctcga aatcgtcgga
     6841 ctgaccgaac gcgccggcca ctatcccgcc cagctttccg gcgggcagaa acagcgtgtc
     6901 ggcatcgccc gcgcactcgc gcccaaaccc caagtcatcc tcgccgacga acccacttcc
     6961 gccctcgacc ccgccaccac gcgcagcgtc ttggaatgtt tggaagacat caacaaacga
     7021 ttcaacgtaa ccatcgtcat cgtaacccac gaaatgagcg tcatcagacg actgtgcgac
     7081 cgcgccgccc tgttggacaa aggcaaagtc gtcgaaatcg tcgaagtacg cggcaaccaa
     7141 atccacgccc gatccgacat cgggcgcgaa ctgattcggg aggactgata tggcagactt
     7201 aacattccaa caagccgttt ccaacatcat cggtatgaaa ggcgaaatcg tccgcgcatt
     7261 gggcgaaacc ttcgtgatgg tcggcttgtc caccacattc gccgtcgttt tcggcacgtt
     7321 gctgggcgtg ttgctcttcg taacttccag ccgccaactg cattacaaca aggcggtgaa
     7381 cttcctgctc gacaacctcg tcaacctcat gcgcgccttc cccttcgtca ttttgatgat
     7441 tgcgatgata cccgccacac gcgccatcgt cggcagcacc atcggtccgg ttgccgcctc
     7501 gctggtgttg agcgtgtcgg gattgtttta ttttgcccgt ttggtggaac aaaacctgcg
     7561 cgaagtcccc aaaggcgtga ttgaagccgc cgccgctatg ggtgcgccgc cggttgccat
     7621 catccgcaaa gtcctcttaa acgaagcgcg cgcgggcatg gtttccagca ttaccgtgct
     7681 tgccatcggg cttttgtcat acagcgcggc ggcagggatg ataggcggcg gcggcttggg
     7741 cgacctcgcc atccgctacg gctactaccg ctaccaaacc gaagtcatcg tcttcatcgt
     7801 cgccctcctc gtgctgctgg tcatcctgat tcaaagcacc ggcaacgcgt tggcgcggaa
     7861 actcgacaaa cgttgaaccc aaatgccgtc tgaacgccaa aacccccacc gctatccgaa
     7921 aaatgctata aaatccccct gttcgcggca aatgccgtct gaacgccgaa tccggacggc
     7981 aggactccct gcccgtcatt tttgtttgaa actgccacaa catcaggaga aaatatgaaa
     8041 accttcttca aaaccctttc cgccgccgca ctcgcgctca tcctcgccgc ctgcggcggt
     8101 caaaaagata gcgcgcccgc cgcatccgct tctgccgccg ccgacaacgg cgcggcgaaa
     8161 aaagaaatcg tcttcggcac gaccgtcggc gacttcggcg atatggtcaa agaacaaatc
     8221 caacccgagc tggagaaaaa aggctacacc gtcaaactgg tcgagtttac cgactatgtg
     8281 cgcccgaatc tggcattggc tgagggcgag ttggacatca acgtcttcca acacaaaccc
     8341 tatcttgacg acttcaaaaa agaacacaat ctggacatca ccgaagtctt ccaagtgccg
     8401 accgcgcctt tgggactgta cccgggcaag ctgaaatcgc tggaagaagt caaagacggc
     8461 agcaccgtat ccgcgcccaa cgacccgtcc aacttcgccc gcgtcttggt gatgctcgac
     8521 gaactgggtt ggatcaaact caaagacggc atcaatccgc tgaccgcatc caaagcggac
     8581 attgccgaaa acctgaaaaa catcaaaatc gtcgagcttg aagccgcgca actgccgcgt
     8641 agccgcgccg acgtggattt tgccgtcgtc aacggcaact acgccataag cagcggcatg
     8701 aagctgaccg aagccctgtt ccaagaaccg agctttgcct atgtcaactg gtctgccgtc
     8761 aaaaccgccg acaaagacag ccaatggctt aaagacgtaa ccgaggccta taactccgac
     8821 gcgttcaaag cctacgcgca caaacgcttc gagggctaca aatcccctgc cgcatggaat
     8881 gaaggcgcag ccaaataagg cagtcgtata aaatgatgcc gtctgaaccg cattccgtgt
     8941 tcagacggca tttttgtcct ttaatccgcc attccctgcc attccgtcga atccggtgta
     9001 tcgattccga acagcgacaa agcgtgtgca acactgtgcg ccactatgtc gtccgccgtc
     9061 tgcggtttgc ggtacatcgc aggaacaggg ggaaacacca cgccgcccat ttccgttacc
     9121 cgcttcatat tgtccaaatg ggcaaggttc agcggcgttt cgcgcaccat cagcaccagc
     9181 cgccgccttt ccttcaaaac cacatccgcc gcacgcgtca agaggttgtc gccgaagccg
     9241 tgcgcgaccg aggcaagtgt ccgcatcgaa cagggggcga ccagcatccc gtccgtttta
     9301 aacgtaccgc tggcaatgca cgccccgata ttgccgatcg gatgcacgaa gtccgccaag
     9361 gcatatacct cgtctctcgc ataagccgtt tccgaagcgc gcgccatctc cgcacctttc
     9421 gataccacaa ggtgcgtttc gatatcttgc gcgcgtaaaa gttccaaagc cttcacgccg
     9481 tattggaaac cgctcgcccc actgatgccg attatcaaac gccgtaccat catccgcctt
     9541 tcccataaaa ccgcctgcaa cggcaaaccg gctattatag tgaaaaaaca gaaatccgat
     9601 aaatacggat acaaattgtc ggcaacaccc aatatccgat aaaatatccg atttaacatc
     9661 ctatctgaat aggcacggga gggcggtatg gcaaaagtaa aaggcggatt ggggcgcggt
     9721 ttggattcgc tgctcgccaa cggcgcagac aacagcagcg gcgaccgatt gaccacggtt
     9781 gcggttaaag atatccggcc cggccgctat caggcgcgtg ttcaaatcga tgacgaagcc
     9841 ttgcaggagc tggcagattc gattaaggcg caaggcgtga tacagcccgt catcgtgcgc
     9901 gaacacggac tgtcccgata cgaactgatt gcgggggagc ggcgttggcg tgccgcacag
     9961 attgccggcc tgaccgaaat ccccgccgtt atcaaaacca tcagcgacga aaccgcgttg
    10021 gcaatgggtt tgatcgaaaa cctccagcgc gaaaacctca accccatcga agaagcacaa
    10081 ggcttgaaac gccttgccga cgagttcggg ctgacccacg aaaccatcgc ccaagccgtc
    10141 ggtaaaagcc gaagcgcgat ttccaacagc ctgcgccttt taagcctgcc cgaacccgtg
    10201 caggaaatgc tttaccaacg ccgcctcgaa atggggcacg cccgcgcact gctgaccctg
    10261 cccgtcgtcg aacagctcga attggcgcaa aaggctgtca aaaacggctg gtcggtgcgc
    10321 gaagtcgaac gccgcagcca agccgccctt caaaacaaac gtcccgagcc caaaaaaact
    10381 gccgccgccg acatcggccg cctgaatgat ttgctgactg aaaaactggg tgtcaacgcc
    10441 gaaatcaaaa ccgccaacca taaaaaaggc agaatcatcc tgcatttcga cacgcccgaa
    10501 accttcgacc atatcttgaa gcaattgggc atagattacc gaccttaatt ttgcgggata
    10561 taccgtctga aatatagaga atagctttcc agattttaag tgggaaatat aattctattg
    10621 acattttttc tgcttcacgt aagaatcgtt ttcctgtttt catttttaat tttcgaggaa
    10681 attatgaaca cacgcatcat cgtttcggct gcgttcgttg cgttggcatt agcaggttgc
    10741 ggctcaatca ataatgtaac cgtttccgac cagaaacttc aggaacgtgc cgcgtttgcc
    10801 ttgggcgtca gcccaaatgc cgtaaaaatc agcaaccgca acaatgaagg catacgcatc
    10861 aactttaccg caactgtggg taagcgcgtg agccaatgct atgttaccag tgtaatcagc
    10921 acaatcggcg ttaccacttc cgatgcaatt tgtttgggag gcggaacgca caaaggcaaa
    10981 agtcaatgca atgctttgct taaagcggca ggccgttgct aatcctttat tcggaaaagg
    11041 tcgtctgaaa atattttcag acgatctttt atttattgag caaattcccc aaactgccga
    11101 caatccgacc gataaactgc tacaatttcg cgttgatttt ttattatttc cacgtaaagc
    11161 aaacaaatca cgtaagaaca ttaaaaatgt aaagaaattg cggacaaact ccttaatatc
    11221 ctgtaattat atgtaatgtg tgttagaatg acacttgtcg ccgttattca ggcggcgagc
    11281 gcggcggatt gggatacgtt gtttcacaaa gattaactgt cgcttgacgt aataaggctt
    11341 ctaaattata ttagccgcgc cccaaatccg aggcggaaac attcccttta tgaagcagat
    11401 tatcatccta caatccgccg tattgtccat atgcgccgca gttgcctttg ctgtatgggg
    11461 ttttgccgga ttcctttcgg cggtcggtgg cggtttgtcc tacctgcttc ccacgtttgt
    11521 tgcagtttta cttttaaaac ttttcagggg aaaccccttc ctgcaaagca ggatgttcgt
    11581 cttcggagag attttaaaag tagtgctgtc gctgttgtcc atgcttgccg tatttgcaat
    11641 atggcatcaa tcgctggtgt tcgccccgtt tctgatgggg ctgctcggtg tcagccattt
    11701 ggttttttta gtattgttga gagtgaaaga ttatggcagg tgaaaccatt accgctgccg
    11761 actacatcaa gcaccacttg cagagcttga ccagtttgtc ggatgttact cagggtcagg
    11821 gactgaaaaa cattgctgat ttttcgttta ttaaccttga tgccgtcttt tttgccgtcc
    11881 tgttgggcgt aatcggcagc tttctgttgt ggcgcggtgc gaaaaaagca acggcaggcg
    11941 ttcccggacg tttccaggct gccgtggaaa tcttgtttga gtttgtggac gatatgtgta
    12001 agagcatcat tcacaacgaa aagtctagaa aagccgtcgc gccgttgggt ctgacgctgt
    12061 ttgtctggat ttttctgatg aacgcgatgg atatgctgcc ggtcgatttg ctgccgatgg
    12121 tatggcaggg cattaccggc aaccatcacg ccctgctgcg cgtcgtaccg actgccgatt
    12181 tgaacaccac tttggcactc gctgtcggcg tgttgctgat ttgtatctat tacaacatca
    12241 aaatcaaagg attgggcggc tggtttcacg agttgttcag cgcgccgttc ggtgcaaaac
    12301 tcgcacctgc gaactttctg ttgaatttgg tcgagtttct ttctaaaacc gtatcccacg
    12361 gtatgcggtt gttcggcaat atgtatgcgg gcgaattggt attcttgctg atagccttgc
    12421 ttggcggtgc ttgggcggct tccggcagcg tcgaagtcat ggatccgatt ctgtttgtat
    12481 tccacattat tgccggtttg gcatgggcga ttttccatat tttggtgatt accctgcagg
    12541 cgtttatttt catggcgttg gcgttcgtct atatcggaca ggcacatgat gcgcactgat
    12601 tttcctaagt agtttgtttt tgtagtttaa cctttgtttc tttaaggagt ttaaaatggg
    12661 tttgattgct atcgcatgtg gtttgatcgt tgcattgggt gcattgggtg cctctatcgg
    12721 tatcgcaatg gtcggttcta aatatttgga gtcttctgcc cgtcagcccg aactgatcgg
    12781 tccgctgcaa accaaactgt tcctgattgc cggtttgatt gatgccgcat tcttgattgg
    12841 tgtcgccatt gcactgctgt tcgccttcgt taacccgttt gcaggtgcat aatcaggacg
    12901 gattcgtccg ttccgtacag gcgcagcctg tttgattaac cccagtacga aggttaagta
    12961 acgtgaatat caatgcaaca ttattcgctc aaatcatcgt ctttttcggt ttggtatggt
    13021 ttaccatgaa attcgtgtgg ccgccgattg caaaagcttt ggatgagcgt gccgcaaaag
    13081 tcgccgaagg cttggctgcc gccgagcgtg gtaaaagcga tttcgagcag gctgaaaaaa
    13141 aggttgcaga actcttggca gaagggcgta atcaggtttc cgaaatggtt gccaacgccg
    13201 aaaaacgtgc cgccaaaatt gtcgaagaag ccaaagaaca ggcttcttcc gaggcggcgc
    13261 gcattgcagc tcaggcaaag gccgatgtgg agcaggaatt gttccgcgca cgcgaatccc
    13321 tgcgcgagca ggttgccgtg ttggctgtca aaggtgccga atctattttg cgcagcgaag
    13381 tcgatgcttc caaacacgca aaactgctcg ataccctgaa acaggagctg taatcttatg
    13441 gcagagttcg caacgattgc cagaccttat gcaaaggcat tgttcggtct ggctcaggaa
    13501 aaaaaccaaa ttgagtcttg gttgggcgga ctggaaaaac ttgcggcggt tgttcaggaa
    13561 gggaaggtgg cttcattgat tgaccgtcct gaaacgaatg cttcagaaaa agcagatatc
    13621 ctcatcgatt tggtcggttt gaaagacaag gagttgaaaa actttgttat cgtcttggcc
    13681 gggcagaaac gtttgtcgat attgccggaa gtatatgctc aatatcaaga cttgacctta
    13741 tcattcaacc atatcaaatc tgccatcatt tacagtgcct atccgttgac cgacaaacag
    13801 gtcggcgagt tggcgcaaat gctgaataag cgtttcgaca gcgagctgaa aatctctgtc
    13861 gaaatcgaac cggagctgat tggcggcata aaagttgaag tgggtgatca ggttttggat
    13921 ttgtctgtac aaggcaaatt gagtgccttg tacacgacta tgacgaatta ggagagtttt
    13981 catgcagctt aatcctgctg aaattagcga tttgattaaa gccaagatcg aaaatctgtc
    14041 tgtaaatgcc gaagtgcgta ctcgtggtac ggtgatttcg gtaactgacg gtatcgttcg
    14101 catccatggt ttgtcagatg caatgcaagg tgagatgctc gaattcccgg gtaacacttt
    14161 cggcttggcg atgaacctgg agcgcgactc cgtcggcgcc gtagtgttgg gcgagtacga
    14221 acatattaaa gaaggcgaca cggttacctg taccggtcgt atcttggaag tgccggtcgg
    14281 gcgcgaactg gtcggacgcg tcgttgatgc attgggtcgg cctatcgacg gcaaaggccc
    14341 gattaataca actttgaccg cccctatcga aaaaatcgca ccgggtgtga ttgcgcgtaa
    14401 atcggttgac caaccaatgc aaaccggctt gaaagccatt gactctatgg ttccggttgg
    14461 tcgtggtcaa cgtgagttga tcattggtga ccgtcaaacc ggtaaaactg ccgtagcact
    14521 ggatgccatc gttaaccaaa aaggtacagg cgtaatctgt atttatgtgg ctatcggtca
    14581 aaaagcatct tctattgcca acgtagtgcg caaattggaa gagcatggcg cgatggaaca
    14641 tactattgta gttgctgcaa ctgcttctga agccgctgcg ctgcaatata tcgctcctta
    14701 ctccggttgt accatgggcg aattcttccg tgaccgcggt gaagatgcgt tgatcgtata
    14761 tgatgacttg tctaaacaag ccgttgcata ccgtcaaatt tccctgctgc tgcgccgtcc
    14821 tcctggtcgt gaagcatatc ctggcgatgt attctacctg cactcccgtc tgttggaacg
    14881 tgcggcccgt gtcagcgaaa acgaagttga aaaactgacc aatggcgaag taaaaggcaa
    14941 aaccggttct ctgactgcat tgccgattat tgaaacccaa gccggtgacg tatcggcatt
    15001 cgtaccaacc aacgtaattt cgattacaga cggccaaatc ttcttggaaa ccgacttgtt
    15061 caacgccggt atccgtcctg caatcaatgc cggtatttcc gtatcgcgcg taggtggtgc
    15121 agcacaaacc aaagtcatca aaaaactggg tggcggtatc cgtttggcgt tggcgcaata
    15181 tcgtgaattg gcggctttct cgcaatttgc atccgatttg gatgaagcta cgcgcaaaca
    15241 attggagcat ggcgaagtcg taaccgaact gatgaaacag aaacagttca gtacgttgaa
    15301 tacggctgaa atggctttga ccctttgggc aatcaacaac ggttcgtatt ctgatgttcc
    15361 ggttgccaaa gctctggctt ttgaatctga atttttgagc tttgtccgta cccaacatcc
    15421 ggaagttttg gaagccgtca atgcttcagg tgcaatgtcc gacgagagcg agaaaacgct
    15481 tgaagcagcc atgaaatcct tcaaatcttc ttacgcctat caggcataag gcttgaagtg
    15541 aaaggagtct gaaatggcag taggaaaaga gattctcacc aaaatccgca gtgttcagaa
    15601 tacccaaaag atcactaaag cgatgcagat ggtgtcaacc tctaaaatgc ggaagactca
    15661 ggaacggatg cgtttggcgc gtccgtatgc cgaaaaagtg cgtatggtga tgagccatct
    15721 tgcgcaaacc aataccgatc atggtattcc gttactggaa tctcatcggg aaatcagacg
    15781 tgtcggtttt attttgatta cgtctgataa gggtttgtgt ggcggtttga acgccaacgt
    15841 gctgaaaaag tttttggcac aagttcaaga gtatcggaat caaggtattg aagaggaaat
    15901 cgtatgcctt ggcagtaaag gtctgatggc gtgtcagagc attggtctga atgtggttgc
    15961 cagtgccgta aatttgggcg ataccccaaa aatggaaatg ctgctcggac ctttgacaga
    16021 actcttccaa cggtatgaga aacatgaaat tgacagaatc catctggtgt attcgggttt
    16081 tgtcaatacc atgcgtcaag aaccgagaat ggaagtattg ctgcctatcg gtgagaacgt
    16141 gattggcgat tcagctccca aatcaccgtt cagctgggaa taccgctacg aaccgactgc
    16201 acttgcagtg ttggaatatc tggttcgccg ctatttagag tctgtggttt atcaggcgtt
    16261 gagcgacaat atggcatccg aacaggcagc ccgcatggtt gccatgaaag ctgcaacaga
    16321 caatgcaggc aatgccatca aagagttgcg tttggtatat aacaaatcgc gtcaagctgc
    16381 gattaccacg gaattgtcag aaattgtagc aggtgcggcg gctgtctgat gccgtctgaa
    16441 tcctgtacgg aaattaggat acgataatga gccaaggcaa aatcgtacaa attatcggtg
    16501 cggttgttga cgtggaattt ccacgcgaca tgattccgcg cgtttacgac gctttgaaat
    16561 tagacgaaaa cggtctgact ttggaagtcc aacagctttt gggcgacggc gtagtccgta
    16621 ccattgcgat gggcagctcg gacggtttga aacgcggcat gactgtgagc aataccggtg
    16681 cgcccattac tgtgccggta ggtaaaggta cgttgggacg cattgtcgat gtattgggaa
    16741 cgcctgttga cgaggcaggt ccgatcgata ccgacaagag tcgtgccatc caccaagccg
    16801 ctcctaagtt tgacgaactg tcttccacaa ccgaattgct cgaaacgggc attaaagtga
    16861 ttgacttgct gtgtccgttt gccaaaggcg gtaaagtagg tctgttcggc ggtgccggtg
    16921 tgggtaaaac cgtgaacatg atggaattga tcaacaacat cgccaaagcg cacagcggct
    16981 tgtccgtgtt cgcaggcgtg ggtgagcgta cccgcgaagg taacgacttc taccacgaga
    17041 tgaaagattc caacgtattg gataaagtgg caatggttta cggtcagatg aacgaacctc
    17101 cgggcaaccg tttgcgcgtc gcattgaccg gtttgaccat ggcggaatac ttccgtgacg
    17161 aaaaagacga aaacggcaaa ggccgcgacg tattgttctt cgtggacaac atctaccgtt
    17221 acactctagc tggtaccgaa gtatccgcat tgttgggccg tatgccgtct gcagtgggct
    17281 accaaccgac attggcagaa gaaatgggtc gtttgcagga gcgtattacc tctacccaaa
    17341 ccggttctat tacttctatc caagccgtat atgtacctgc ggacgacttg accgacccgt
    17401 ctccggcaac aacgttcgcc cacttggacg caaccgtcgt attgagccgc gatattgcct
    17461 ctttgggtat ttacccggca gtcgatccgc ttgattccac ttcgcgccaa ctggatccga
    17521 tggtcttggg tcaagagcac tacgacgtgg cgcgcggcgt acagtccacc ctgcagaaat
    17581 acaaagaatt gcgcgacatc atcgccatct tgggtatgga cgaattgtct gacgaagaca
    17641 aactgaccgt aatgcgtgcg cgtaaaatcc aacgcttcct gtcccaaccg ttccacgttg
    17701 ccgaagtgtt tacaggttct ccgggcaaat atgtcgccct gcgcgatacc attgccggct
    17761 tcaaagccat cttgaacggc gaatacgatc atctgcccga gcaggcattc tatatggtcg
    17821 gcagcattga agaagcggtt gagaaagcga aaaccttaaa ctgaggaggt cggcatgagc
    17881 atcatgcaag ttgaggtggt aagtagcgag cagaaaatct attcaggcga ggcaacattt
    17941 atcgttgttc cgactgtaca gggcgaactc ggtatttatc cgcgacacga gccgattatg
    18001 agtttggtgc ggccgggggc tttgcgtttg accgttccgg gcgaggataa agaggttttg
    18061 gttgctgttt ccggcggtgt tttggaagta cagcctgata aagtaactgt cttggcggat
    18121 gttgccgtcc gcagtgcaga gatggatcag gcacgtgcgg aagaggcgaa aaaagccgca
    18181 gaagcgggca tttcccaagc taaagacgat aaggctttgg cggaggcgca taaagcattg
    18241 gctgctgcga ttgcacagct taaaactttg gactatatcc gttcgcacaa gaaataaact
    18301 tgtttggttt ggaaaagcac gaccgtttgg tcgtgctttt tattttccgg atttaaatta
    18361 aagactgtgt ttggatatgg cgttggcagg catagcctgc tttaaggtat tcaatagggc
    18421 agcctgccgc ctaaccgaaa catatagcgg attaacaaaa atcaagacaa ggcgacgaag
    18481 ccgcagacag tacaaatagt acggaaccga ttcacttggt gcttgagcac cttagagaat
    18541 cgttctcttt gagctaaggc gaggcaacgc tgtactggtt taaatttaat ccactatatc
    18601 atgtatgccg tgttttcaaa tcagtctgtc tttgagataa acctatccaa acagcaatgg
    18661 aaacagtaaa ataaaccctt tattttatcg aatcataagc catgcttacc ttccaacaaa
    18721 tcatcttcaa actgcaaacc ttctgggcag acaaaggctg caccgtcatc caacccttcg
    18781 acatggaagt cggtgccggc acatcccatc ccgccacctg cctgcgcgcg ctcgggcccg
    18841 agccttggtt tgccgcctac gtccaaccca gccgccgccc caaagacggc cgctacggcg
    18901 acaaccccaa ccgcctgcaa cactattacc aattccaagt cgccctcaaa cccgcccccg
    18961 ccaatatcca agacctttat ctcgactccc tgcgcgaatt gggcatcgac cccaaagtgc
    19021 acgacatccg cttcgtcgaa gacgactggg aaaaccccac cctcggcgca tggggcttgg
    19081 gctgggaagt ttggctcaac ggcatggaag taacccagtt tacctatttc caacaagtcg
    19141 gcggcatcga ctgcacgccc gtactcggcg aaatcaccta cggcatcgaa cgcttggcga
    19201 tgtacctgca aggcgtggaa aacgtctatg acctcgtttg ggcaaaaacg ccggacggca
    19261 acaccgtaag ctacggcgac gtgtaccacc aaaacgaagt cgaacaatcc acctacaact
    19321 tcgaatacag cgatgccgat tggctgctgc gccagttcaa cgactacgaa gcgcaagcca
    19381 aacgcctgct tgccgaagaa aacgccgccc tcgccttgcc tgcctacgag ctggttctca
    19441 aagcggggca tacgttcaat cttttagacg cacgcggcgc gatttccgta accgagcggg
    19501 caacttatat tggacgtatt cgtgcattga gccgcgccgt ggcgcaaaaa tatgttgaaa
    19561 gccgcgaaaa actgggcttc cctttaatga aggcaaatgc tgcctaaggg ggcgacgatt
    19621 ttttacgttc gggcggcacg ataaggcagc cgtccgtaaa ccattatata ttttaggaaa
    19681 atcatgcctg tctatttccg caccccaagc aggaaacgcc tgcacaaaat gaaccgccgc
    19741 cagcataaaa agctgcattt gggcgagttt caaacattga ttttcggcgt tcaaggcagt
    19801 ttgcaccaag ctgaggacga tgccgaagcg ttcgaccgct ttatggacga gctgattgcg
    19861 tatcttgagg taaacgactt tggaatggcg ggcgggggcg attgcggcga tttttcgtgc
    19921 ctgtttcaaa aatccggtgc ccgaagcttg ggcgaaaccg agaaaaaagc cattatctct
    19981 tggctggcag gccgcgaaga tgtcgccact ttgcacacca ccccgctggt tgacggtttt
    20041 tacggggatg acggctggga aaattacagt gaaacctata aacaggcaga ttaaccaaat
    20101 ttaaagaaag ccgaatgatg acccaaaccc ttttaatcga actccttacc gaagaactcc
    20161 cgcccaaagc actgaataat ctgggcaacc attttgccgc cgccgttgcc gaaggcttgg
    20221 aaaaagcgca actggttgac ggtgcagccg aatttacggc ttatgcctcg ccgcgccgtt
    20281 tggcggttca agtcaaaaac gttaaagccg ttcaggccga ccaaaaaatc gtgaaaaaag
    20341 gccctgccgt ggcgaatgcc atgaaagacg gtgcgccgac caaggctttg gaaggtttcg
    20401 cacgcggtgc gggcgcgaaa atcgaagact tgaccatcgt ccacgacggc aaacaggatg
    20461 tgtacgccta cgaatacgtc caaaccggca aaccgctggg cgaacttttg gaagacatta
    20521 tcaatcaagc cgttaagaaa ctgccgattc cgaaagtgat gcgttggggc agcagcacgt
    20581 ttaccttcgt gcgccctgtt cacgggctga ttgtgctgca cggcggcgac atcgtaaacg
    20641 tcagcgtttt gggtctgcaa agcagcaatc aaaccttggg acaccgcttc ttgtccaacg
    20701 gcgaaatcac cattgaaaac gccgacagct acgccgaaca aatgcgcggg caaggcaaag
    20761 tcgtcgcttc gtttgccgag cgcaaagccg cgattcagac ggcattggaa gggcaggcgc
    20821 gcagtctgaa cgccgccgtc gccgccgatg aagcattgtt ggacgaagta accgcgctgg
    20881 tcgaatggcc tgttgttttg gaagccggtt ttgaggaaca tttcctcgcc gtgccgcagg
    20941 aatgcttgat tttaacgatg cagcaaaacc aaaaatactt tccgctgctc gaccaaaacg
    21001 gcaagctgat gaaccgcttc ctgctggttt ccaacctgca aaccgaagac ccgtcgcaca
    21061 tcatccgagg caacgaacgc gttttgcgcg cgcgcctgtc tgatgccgag ttcttctaca
    21121 aacaagacca aaaagcgact ttggaaagcc gcctgccgaa attgtccagc gtggtgtacc
    21181 acaacaaaat cggctcgcaa gccgaacgca tcgaacgcct gcaaagcatt gccgcccaca
    21241 tcgccaaagc attgggcgcg gatgccgccg ctgccgaacg cgccgcgcgt cttgccaaag
    21301 ccgacttggt aaccgaaatg gttggcgagt tccccgaact gcaaggcacg atgggcaaat
    21361 actatgcacg tttggacggc gaaaccgaag aaatcgccga agccatcgag cagcactatc
    21421 agccgcgttt tgccggcgac aagctgcccg aaagcaaaat tgccgccgcc gtggcactgg
    21481 cggacaagct ggaaaccctg gtcggcattt ggggcatcgg tctgattccg accggcgaca
    21541 aagaccccta cgccctgcgc cgcgccgcct tgggtatttt gcggatgctg atgcagtacg
    21601 gtttggacgt gaacgaactg attcagacgg cattcgacag cttccccaaa ggtttgctca
    21661 acgaaaaaac gccgtctgaa accgccgact ttatgcaggc gcgccttgcc gtgttgctgc
    21721 aaaacgatta tccgcaagac atcgtcgccg ccgtactcgc caaacagccg cgccgtttgg
    21781 acgatttgac cgccaaactg caagccgttg ccgcgttcaa acagctgccc gaagccgccg
    21841 cgctcgccgc cgccaacaaa cgcgtgcaaa acctgctgaa aaaagccgat gccgcgttgg
    21901 gcgcggttaa cgaaagcctg ttgcaacagg acgaagaaaa agccctcttt gccgccgcgc
    21961 aaggcttgca gccgaaaatc gccgccgccg tcgccgaagg caatttccaa accgccttgt
    22021 ccgaactggc ttccgtcaaa ccgcaagtcg atgcattctt tgacggcgtg atggtaatgg
    22081 cggaagatgc cgccgtaaaa caaaaccgcc tgaacctgct gaaccgcttg gcagagcaaa
    22141 tgaacgcggt agccgacatc gcgcttttgg gcgagtaacc gttgtacagt ccaaatgccg
    22201 tctgaagcct tcagacggca tcgtgcctat cgggagaata aattgcagcc tttagtcagc
    22261 gtattgattt gcgcctacaa cgtagaaaaa tatttcgccc aatcattagc cgccgtcgtg
    22321 aatcaaactt ggtgcaactt ggatattttg attgtcgatg acggctcgac agacggtacg
    22381 cttgccattg ccaaggattt tcaaaagcgg gacagccgta tcaaaatcct tgcacaagct
    22441 caaaattccg gcctgattcc ctctttaaac atcgggctgg acgaattggc aaagtcgggg
    22501 gggggggaat atattgcacg caccgatgcc gacgatattg ccgcccccga ctggattgag
    22561 aaaatcgtgg gcgagatgga aaaagaccgc agcatcatcg cgatgggcgc gtggctggaa
    22621 gtgttgtcgg aagaaaagga cggcaaccgg ctggcgcggc atcacaggca cggcaaaatt
    22681 tggaaaaagc cgacccggca cgaagatatt gccgactttt tccctttcgg caaccccata
    22741 cacaacaaca cgatgattat gcggcgcagc gtcattgacg gcggtttgcg ttacaacacc
    22801 gagcgggatt gggcggaaga ttaccaattt tggtacgatg tcagtaaatt gggcaggctg
    22861 gcttattatc ccgaagcctt ggtcaaatac cgccttcacg ccaatcaggt ttcatccaaa
    22921 tacagcgtcc gccaacacga aatcgcgcag ggcatccaaa aaaccgccag aaacgatttt
    22981 ttgcagtcta tgggttttaa aacccggttc gacagccttg aataccgcca aataaaagca
    23041 gtagcgtatg aattgctgga gaaacatttg ccggaagaag attttgaacg cgcccgccgg
    23101 tttttgtacc aatgcttcaa acggacggac acgctgcccg ccggcgcgtg gctggatttt
    23161 gcggcagacg gcaggatgcg gcggctgttt accttgaggc aatacttcgg cattttgcac
    23221 cgattgctga aaaaccgttg aaaaacgccg ctttatccaa cagacaaaaa acaggataaa
    23281 ttatgcaaaa ccacgttatc agcttagctt ccgccgcaga acgcagggcg cacattgccg
    23341 caaccttcgg cgcgcgcggc atcccgtttc agtttttcga cgcactgatg ccgtctgaaa
    23401 ggctggaaca ggcaatggcg gaactcgtcc ccggcttgtc ggcgcacccc tatttgagcg
    23461 gagtggaaaa agcctgcttt atgagccacg ccgtattgtg gaaacaggca ttggacgaag
    23521 gtctgccgta tatcgccgta tttgaggacg acgttttact cggcgaaggc gcggagaaat
    23581 tccttgccga agacgcttgg ctaaaagaac gctttgaccc cgattccgcc tttatcgtcc
    23641 gcttggaaac gatgtttatg cacgtcctga cctcgccctc cggtgtggcg gactactgcg
    23701 ggcgtgcctt tccgctgttg gaaagcgaac actgggggac ggcgggctat atcatttcca
    23761 aaaaagcgat acggtttttc ctgcaacatt tcgtaatgtt gcagccggaa cagataaaac
    23821 ctatcgactt aatgatgttc agtgattttt tcgataagga ggggatgcct gtttatcagg
    23881 tcagtccggc cttatgcgcc caagagctgc attatgccaa gtttcacgac caaaacagcg
    23941 cattgggcag cctgatcgaa cacgaccgcc tcctgaaccg caaacagcaa aggcgcgatt
    24001 cccccgccaa cacattcaaa cgccgcctga tccgcgcctt gaccaaaatc agcagggaaa
    24061 gggaaaaacg ccggcaaagg cgcgaacagt tcattgtgcc tttccaataa aaggaggaga
    24121 gatggacatc gtatttgcag cagacggcag gatgcggcgg ctgtttacct tgaggcaata
    24181 cttcggcatt ttgcgccgat tgctgaaaaa ccgttgaaaa acgccgcttt atccaacaga
    24241 caaaaaacag gataaattat gcaaaaccac gttatcagct tagcttccgc cgcagaacgc
    24301 agggcgcaca ttgccgatac cttcggcagg cacgacattc cgtttcagtt tttcgacgca
    24361 ctgatgccgt ctgaagaact gaatcgggtg atggcggaat tggtgccggg attggcaaaa
    24421 cagcacctgt tgagcgaagt ggaaaaagcc tgctttatga gccacgccgt attgtggaaa
    24481 caggcattgg atgaaggtct gccctatgtt gccgtatttg aggatgatgt cctgcttggc
    24541 aaagacgcag aaaagttcct tgccgaagat acttggttgg aagagcgttt tgataaggat
    24601 tctgccttta tcgttcgttt ggaaacgatg tttgcgaaag ttattgtcag accggataaa
    24661 gtcctgaatt atgagaaccg gtcatttcct ttgctggaga gcgaacattg ggggacggct
    24721 ggctatatca tttcgcgtga ggcgatgcgg tttttcttgg aaaggtttgc cgttttgccg
    24781 gcagagtgga ttaaagcggt agattggatg atgtttactt atttctttga taaggagggg
    24841 atgcctgttt atcaggttaa tcccgcctta tgtacccaag aattgcatta tgccaagttc
    24901 ctcagtaaaa acagtatgtt gggtagcgat ttggaaaaag atagggaaca agaaagaaga
    24961 caccgccgtt cgttgaaggt gatgtttgac ttgaagcgtg ctttgggtaa attcggtagg
    25021 gaaaagaaga aaagaatgga gcgtcaaagg caggcggagc ttgagaaagc ttacggcagg
    25081 cgggtcatat cgttcaaata gtttgtgtaa aatatagcgg attaaaatta gaaatggata
    25141 cactgtcatt cccgcgaaag tgggaatcca gtccgttgag tttcagtcat ttccgataaa
    25201 tcaccgcaac gttaaatttc tagattcccg cttttgcggg aatgacggcg ggggattttt
    25261 gtttttccga caaattccta aaacttaaaa ttccgttatt cccgcgaaaa cagaaaacca
    25321 aaaa
//
LOCUS       DAXISH010000024        25207 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.024, whole genome shotgun sequence.
ACCESSION   DAXISH010000024 DAXISH010000000
VERSION     DAXISH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 25207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25207
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.024"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..206
                     /locus_tag="ACFOV4_001013"
     CDS             <1..206
                     /locus_tag="ACFOV4_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC7619042.1"
                     /translation="ENQTKRNRYLSKTRYVVEQSFGTLHRKFRYARAAYFGLIKVSAQ
                     SHLKAMCLNLLKAANRLSAPAAA"
     gene            complement(419..649)
                     /locus_tag="ACFOV4_001014"
     CDS             complement(419..649)
                     /locus_tag="ACFOV4_001014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619043.1"
                     /translation="MLPTRKTARKIQARHIALPFSGKPQFYRPQERLSKQAQATPPGH
                     FPFSTAIRRPDCAAAPSAHHAFRAAAGGNIVD"
     gene            709..1332
                     /locus_tag="ACFOV4_001015"
     CDS             709..1332
                     /locus_tag="ACFOV4_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HFC7619044.1"
                     /translation="MKKPTDTLPVNLQRRRLLCAAGALLLSPLAHAGAQREETLADDV
                     ASVMRSSVGSVNPPRLVFDNPKEGERWLSAMSARLARFVPEEEERRRLLVNIQYESSR
                     AGLDTQIVLGLIEVESAFRQYAISGVGARGLMQVMPFWKNYIGKPAHNLFDIRTNLRY
                     GCTILRHYRNLEKGNIVRALARFNGSLGSNKYPNAVLGAWRNRWQWR"
     gene            1443..2825
                     /locus_tag="ACFOV4_001016"
     CDS             1443..2825
                     /locus_tag="ACFOV4_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC7619045.1"
                     /translation="MARDNRIQMFPHEWRASTTLSGVYALRMLGMFLVLPVLAVYAAS
                     LPGAEGNKTLVGLAMGIYGLTQALLQLPLGIASDKFGRKKTIYAGLVVFAAGSFLAAA
                     ADTLPMLVAARAIQGAGAVSAAVTALLADLTRDGVRTRAMAMIGLSIGLTFSVSLVVA
                     PVIADAVGVRGLFLLTGILTVASIGVVAWMTPDPEVSKLHEDTQAQPSRIGEVLKNRR
                     LLTLDFGIFALHAAQMALFTALPFAMTQLGLEKIQHWKVYLPSTITGLVVMVPLIIVG
                     ETRNKLKQVFVLGIVCIAAAQLGLLSGMRSVGLITAYLVVYFIGFNVLEASLPSMVSK
                     IAPSDLKGTAMGVYNTMQSLGLFAGGAAGGLLFQKYGFSGVFAFCSILMLLWLVIAVL
                     SPAPKPVKNLSYPVGGVWQGNQDGLQCALSQLEGVEDIGFSFDRQTVYLKVLQKGFDQ
                     AAAEKIITGV"
     gene            2829..3353
                     /locus_tag="ACFOV4_001017"
     CDS             2829..3353
                     /locus_tag="ACFOV4_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFC7619046.1"
                     /translation="MSLNKVILIGRLGRDPEVRYMPNGEAVCNFSVATSETWNDRNGQ
                     RVERTEWHNITMYRKLAEIAGQYLKKGGLVYLEGRIQSRKYQGKDGIERTAYDIVANE
                     MKMLGGRNENSGGAPYEEGYGQSQEAYQRPAQQSRQPASDAPSHPQEAPAAPRRQPVP
                     AAAPVEDIDDDIPF"
     gene            3878..4801
                     /locus_tag="ACFOV4_001018"
     CDS             3878..4801
                     /locus_tag="ACFOV4_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFC7619047.1"
                     /translation="MENQRPLLGFALALLAAMTWGTLPIAVRQVLKFVDAPTLVWVRF
                     TVAAAVLFVLLALGGRLPKRRDFSWCSFRLLLLGVAGISANFVLIAQGLHYISPTTTQ
                     VLWQISPFTMIVVGVLVFKDRMTAAQKIGLVLLLAGLLMFFNDKFGELSGLGAYAKGV
                     LLCAAGSMAWVCYAVAQKLLSAQFGPQQILLLIYAASAAVFLPFAEPAHIGSLDGTLA
                     WVCFAYCCLNTLIGYGSFGEALKHWEASKVSAVTTLLPVFTVIFSLLGHYVMPDTFAA
                     PDMNGLGYVGALVVVGGAVTAAVGDRLFKRR"
     gene            complement(4866..6254)
                     /gene="fumC"
                     /locus_tag="ACFOV4_001019"
     CDS             complement(4866..6254)
                     /gene="fumC"
                     /locus_tag="ACFOV4_001019"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045239 - tricarboxylic acid cycle
                     heteromeric enzyme complex [Evidence IEA];
                     GO_function: GO:0004333 - fumarate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006106 - fumarate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HFC7619048.1"
                     /translation="MSTRTEHDTMGNVEVPSEAYWGAQTQRSRNNFKIGGETLPQPLI
                     YALALVKKAAAATNVSLGRIKPEQADLITQAADDVLNGRLDGQFPLVVWQTGSGTQSN
                     MNMNEVLANRANEIAGTGLAAYQPVHPNDHVNHAQSTNDAFPTAIHVAAAIEINRHLI
                     PAVKALRDTLDKKAQAFAPIVKIGRTHLQDATPLTLGQEFSGYVSQLDHGLGRLNDAL
                     KDLYELALGGTAVGTGLNSHPEYAEKAAAKLAELSGLPFVSAPNKFEALGGRDAAVAA
                     SGALKTLAASLNKIANDIRWLASGPRCGLGEIKIPENEPGSSIMPGKVNPTQCEAMTM
                     VCCQVFGNDVTIGMAGASGNFELNVYMPVIAYNLLQSIRLLGDACNSFNEHCAVGIEP
                     VPEKIDYFLHHSLMLVTALNRKIGYENAAKVAKTAYKNNKSLRETAVELGLLTGEEFD
                     ELVVPADMVHPR"
     gene            complement(6395..8374)
                     /gene="tkt"
                     /locus_tag="ACFOV4_001020"
     CDS             complement(6395..8374)
                     /gene="tkt"
                     /locus_tag="ACFOV4_001020"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFC7619049.1"
                     /translation="MSQLANAIRFLSADAVQKANSGHPGAPMGMAEMAETLWTKFLNH
                     NPANPKFYNRDRFVLSNGHASMLLYSLLHLTGYNLSIEDLKNFRQLHSKTPGHPEYGY
                     TDGVETTTGPLGQGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVS
                     HEACSLAGTLGLGKLIVLYDDNNISIDGKVDGWFTENIPQRFESYGWHVVPNVNGHDT
                     AAIQAAIEAARAETGKPSIICCKTLIGKGSANKEGSHKTHGAPLGADEIEATRKHLGW
                     TYPAFEIPQEIYDAWNAKEQGAKLEADWNELFAQYQAKYPAEAAEFVRRMDKKLPDNF
                     DEYVQTALKEVCAKAETIATRKASQNSIEILAKELPELVGGSADLTPSNLTDWSNSVS
                     VTRDKGGNYIHYGVREFGMGAIMNGLALHGGIKPFGATFLMFSEYERNALRMAALMKI
                     NPVFVFTHDSIGLGEDGPTHQPIEQTATLRLIPNMDVWRPCDTAESLVAWAEAVKAAD
                     HPSCLIFSRQNLKFQARSEQQLDDIKRGGYIISEAQGNAQAVIIATGSEVELALEAQK
                     ALAAQNIAVRVVSMPSTNVFDRQDAAYQAAVLPESLPRIAVEAGHADGWYKYVGLNGA
                     VVGINRFGESAPADLLFKAFGFTVDNVVDTVKSVL"
     gene            8901..10397
                     /gene="ccoG"
                     /locus_tag="ACFOV4_001021"
     CDS             8901..10397
                     /gene="ccoG"
                     /locus_tag="ACFOV4_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003708970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008535 - respiratory chain complex IV
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase accessory protein CcoG"
                     /protein_id="HFC7619050.1"
                     /translation="MTTENQAGSPASGIGTSEQTKAAPKAKKTFDPRASVIQIHPEGE
                     RIHPKKAEGRFAKLRIAAVLATQFVFYVIPWFNWSGRQAVVFNIPERHFFIFGLSLGV
                     GDLIYLALLLMICAFGLFWWTTIAGRLWCGYSCPQTVYTEIMLWIDNLVEGDRNKRLK
                     LEKSPWNFTKIRIKATKYLLIFLVCAWTGITFAGWFVPIRQFVPDLFTGAAGGGAMFA
                     AAFYGFMTFFFAHIMREKVCLHMCPYARFQSAMFDKDTLIVSYDAERGEPRGARKKTV
                     NKEEAGLGDCINCAMCVQVCPVGIDIRNGLQYQCIGCAACIDACDEIMDKMGYPRGLI
                     RYTTESALEHEYSEKDIKKRLLRPRVAGYGAVLALVIIAFLAGLSTRKMVEVDILKDR
                     GVLVRENAKGWLENAYSLRIINKSEKEQLITASVKGFDEIALTGLPEGGIKVAPRETV
                     TLPVQVSTIPEYADKGSHPIEFTFQYRESGAPDGKPVVLEEDATFIGE"
     gene            10400..10948
                     /locus_tag="ACFOV4_001022"
     CDS             10400..10948
                     /locus_tag="ACFOV4_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FixH family protein"
                     /protein_id="HFC7619051.1"
                     /translation="MSQNTPIKPWYKHVWPWILMAGPIFVVIASVAMFFVAQQHATDL
                     VTDDYYKDGKHIDIQLHRDEEAVRRHIGVQVLISPDMNAAKVFVGGEFDGKQPLNLLL
                     MHPTRKADDQTVALKPVGSAQNGRAEYEAVFKTLSPTNHWYVRVEDAAGVWRVENKWI
                     TSQGNAVDLTPMDKLFNNAGSK"
     gene            complement(11071..11259)
                     /locus_tag="ACFOV4_001023"
     CDS             complement(11071..11259)
                     /locus_tag="ACFOV4_001023"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619052.1"
                     /translation="MPSEAFQTAFFRLRFGIVSKKRREIKTFLCKQNAFRIVSGIQHK
                     CRLKPFRRHFSGCISEWC"
     gene            complement(11289..12464)
                     /locus_tag="ACFOV4_001024"
     CDS             complement(11289..12464)
                     /locus_tag="ACFOV4_001024"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HFC7619053.1"
                     /translation="MQNIFDPLVIRGKSLTPIVQGGMGVGVSASGLSSAVARENGIGT
                     IASVDLRHLHEDLLAESQINPSEEKYTSLNCTALDREIQKAKSASEGKGLIAVNVMKA
                     VKDHAAYVRQACESGADAVVMGAGLPLDLPEMTEGYHKDVALLPILSESRGINIVLKR
                     WMKKGILPDAIVVEHPAHAAGHLGASTVEGVNDAKFDFKRVIEETFEVFKSLGLESEK
                     IPLILAGGMANFEKVKTALKNWGASAVQIGTAFAVTEEGDAHLNFKKTLAGAETEKVV
                     EFMSVAGLPARGVRTKFLDSYIKRESKLQANAKADPRRCTQGLNCLTSCGLRDGLSKA
                     GQFCIDIQLAAAFRGEVDKGLFFRGKDPLPFGNAIRTVRETIQYLLTGSEPVATLGR"
     gene            complement(13023..13097)
                     /locus_tag="ACFOV4_001025"
     tRNA            complement(13023..13097)
                     /locus_tag="ACFOV4_001025"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13062..13064),aa:Glu,seq:ttc)
     gene            complement(13115..13191)
                     /locus_tag="ACFOV4_001026"
     tRNA            complement(13115..13191)
                     /locus_tag="ACFOV4_001026"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13155..13157),aa:Arg,seq:acg)
     gene            13309..14694
                     /locus_tag="ACFOV4_001027"
     CDS             13309..14694
                     /locus_tag="ACFOV4_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFC7619054.1"
                     /translation="MIVASRWPLLEKVFLRFGMPVAVVDLESTGGNLYEDRVTEVALV
                     KFEQGRVVRHEWLVNPQKPIPQFVAGLTGISDGMVADAPVFAEIAGELFSVLKGCVLV
                     AHNSRFDYTFLKHEFHRAGIGFSSPALCSVQLSRCLYPQFYKHSLDSIIERLGIVVED
                     RHRAMADVSALCDYLEYSLSEHGVEEWIRQCFRLMNPKPLPAALPERLREQLYGLPDG
                     MGVLACFDGGGKVNYIGTFERVYSEVSALLDSGKAPFDWCNTEEVRFFPALGRLHAHK
                     VKAELVRHYGVDCYVSAKNLLKTFTTVRFEKGSDGILNAKTADLKNGVTDNPPTGLFA
                     NKKAARRALSSWAETYGLCPAAAGILPDGYAEDEPCPVYVSGRCDKACGRSDEQVLAF
                     AHKLPVLDWGKMHEVEITETDPLTGEKVVLHGMGGALEMDDGLWYFDKDLPDAFKAKF
                     KTDRKNIKEIG"
     gene            complement(14899..15678)
                     /locus_tag="ACFOV4_001028"
     CDS             complement(14899..15678)
                     /locus_tag="ACFOV4_001028"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004324 - ferredoxin-NADP+ reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP reductase"
                     /protein_id="HFC7619055.1"
                     /translation="MAASPEAKFTEEKILWVKHHTPKLITFAISRPESYRFKAGQFSR
                     LGFYEGEGFIWRSYSIVSAEYADTLEYFAVLIQDGPMSARFAKMQQGDTILLDKNATG
                     FLLPERFPDGKDLVMLCTGSGIAPFLSILEQPEIRQRFDTVNLIHSVSFPEELIFNDR
                     LAALSEHPLVGEYRHSFHFVPVTTRAANPSGLSGKRIPELLKNSSIEQALHTKFTPES
                     TRFMICGNPEMVKDTFQTLLDMGYAMHRNRIPGQIMMENGF"
     gene            15952..19040
                     /locus_tag="ACFOV4_001029"
                     /pseudo
     CDS             15952..19040
                     /locus_tag="ACFOV4_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212999.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
     gene            19184..20242
                     /gene="dinB"
                     /locus_tag="ACFOV4_001030"
     CDS             19184..20242
                     /gene="dinB"
                     /locus_tag="ACFOV4_001030"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFC7619056.1"
                     /translation="MSSRKIIHIDMDAFYASVELREQPHLKGRPVVVAWEGARSVICA
                     ASYEARQFGLHSAMSVATAKRLCPQAVYVPPHFDLYRQVSAQIHAVFRRYTDLIEPLS
                     LDEAYLDVTRNFKNIPYDSEVAKEIRAAIFAETGLTASAGIASNKFLAKIASDWRKPN
                     GQFVLPPHKVMAFLETLPLGKIPGVGKVTLKKMQSLGMQTAGDLRRFERGELLNHFGR
                     YGYRLYDLARGTDERPVKAERERLQISTEITLPEDLPLEQAAGHLPHLAEDLWRQITR
                     KNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCASLLQAAQMLMARVPPQTEDAFRLI
                     GIGVGHLVPKNQQQDLWA"
     gene            complement(20310..22325)
                     /gene="rep"
                     /locus_tag="ACFOV4_001031"
     CDS             complement(20310..22325)
                     /gene="rep"
                     /locus_tag="ACFOV4_001031"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HFC7619057.1"
                     /translation="MMKLNPQQLEAVRYLGGPLLVLAGAGSGKTGVITQKIKHLIVNV
                     GYLPHTVAAITFTNKAAAEMQERVAKMLPKPQTRGLTICTFHSLGMKILREEANHIGY
                     KKNFSILDSTDSAKIIGELLGGTGKEAVFKAQHQISLWKNDLKTPEDVVQTASNAWEQ
                     QTARLYASYQETLQSYQAVDFDDLIRLPAVLLQQNSEVRNKWQRRLRYLLVDECQDTN
                     TCQFTLMKLLTGAEGMFTAVGDDDQSIYAWRGANMENLRKMQENYPQMKVIKLEQNYR
                     STARILKIANKVIENNPKLFTKKLWSQFGEGDPVKVVACQNEQHEADWVVSQIVKQKL
                     IGGDKTQYADFAVLYRGKHQARIFEEALRGARIPYRLSGGQSFFDKAEIKDVLSYVRL
                     LANPNDDPAFLRAVTTPKRGIGDVTLGKLNTYAHEHECSLYEAAQNEEALATLNNTNR
                     QHLQAFMDMFGSYRAKAETGEAGEFINNLLKEIDYENHLLASEESKAGEIKWRNVGDL
                     VSWFARKGGEDGKNVIELAQTVALMTLLEGKDEEETDAVSLSTLHAAKGLEYPYVFLV
                     GCEEGVLPHNDSIEEGNVEEERRLMYVGITRAKRQLTLTHCVKRKKQGIWQFPEPSRF
                     IDEMPQEDLKILGRKGGEPIVSKEEGRRNLADIIGRLDNLKKSGAAD"
     gene            complement(22345..23109)
                     /gene="aroD"
                     /locus_tag="ACFOV4_001032"
     CDS             complement(22345..23109)
                     /gene="aroD"
                     /locus_tag="ACFOV4_001032"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFC7619058.1"
                     /translation="MCSCLVVKNTVIGSGRTKIAVPLVARDAAVLSAVLDQIKNLPFD
                     IVEFRADFLECAGSIGEVLRHTQTVRDALPDKPLLFTFRRHGEGGSFPCSDDYYFELL
                     DALIESRLPDIIDIELFSGETAVRCAVANAQKNGIAALLCNHEFHRTPPQEEIVCRLK
                     QMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTGAVSRLAGQV
                     FGSSITFGSGTQNSAPGQIGVSALRATLDCLENGAD"
     gene            23363..24409
                     /gene="recA"
                     /locus_tag="ACFOV4_001033"
     CDS             23363..24409
                     /gene="recA"
                     /locus_tag="ACFOV4_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFC7619059.1"
                     /translation="MSDDKSKALAAALAQIEKSFGKGAIMKMDGSQQEENLEVISTGS
                     LGLDLALGVGGLPRGRIVEIFGPESSGKTTLCLEAVAQCQKNGGVCAFVDAEHAFDPV
                     YARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGDMG
                     DSHVGLQARLMSQALRKLTGHIKKTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFY
                     SSVRLDIRRTGSIKKGEEVLGNETRVKVIKNKVAPPFRQAEFDILYGEGISWEGELID
                     IGVKNDIINKSGAWYSYNGAKIGQGKDNVRVWLKENPEIADEIDAKIRALNGVEMHIT
                     EGTQDETDGERPEE"
BASE COUNT         5707 a         6165 c         7157 g         6178 t
ORIGIN      
        1 cggaaaatca aaccaagcgt aaccgatatt tgtcgaagac ccgttatgtg gttgaacaaa
       61 gcttcggtac gctgcaccgt aaattccgct acgctcgggc agcctatttc ggactgatta
      121 aagtgagtgc gcaaagccat ctgaaggcga tgtgtttgaa cctgttgaaa gccgccaaca
      181 ggctaagtgc gcccgctgcc gcctaaaaag cagcccggat gcctgattat cgggtgtccg
      241 tggaggatta agggggtatt tgggtaaaat taggaggtat ctggggcgaa aacagctgaa
      301 aacctgtgtt ggggtttcgg ctgtcgggag ggaaaggaat tttgcaaagg cctcaagata
      361 tagtggatta aatttaaatt agtacggtaa gacgaggcaa cgctgtactg gtttaaattt
      421 aatctactat atttccgcct gctgccgccc gaaaagcgtg atgcgctgat ggtgctgctg
      481 cacaatccgg acgacggata gccgttgaaa acgggaaatg cccgggcggt gtcgcctgtg
      541 cctgtttgga caagcgttct tgagggcggt agaattgagg tttgcccgaa aagggcaggg
      601 cgatatgccg cgcttggatt ttgcgcgcgg tttttcgcgt tggaagcaat cattgtctgt
      661 ttgaatattt aatgccgtct gaaacgtccg gacgcgcccc cgttccctat gaaaaaaccg
      721 accgataccc tacccgttaa tctgcaacgc cgccgcctgt tgtgtgccgc cggtgcgttg
      781 ttgctcagtc ctctggcgca cgccggcgcg caacgtgagg aaacgcttgc cgacgatgtg
      841 gcttccgtga tgaggagttc tgtcggcagc gtcaatccgc cgaggctggt gtttgacaat
      901 ccgaaagagg gcgaacgttg gttgtctgcc atgtcggcac gtttggcaag gttcgtcccc
      961 gaggaggagg agcggcgcag gctgctggtc aatatccagt acgaaagcag ccgggccggt
     1021 ttggatacgc agattgtgtt ggggctgatt gaggtggaaa gcgcgttccg ccagtatgca
     1081 atcagcggtg tcggcgcgcg cggcctgatg caggttatgc cgttttggaa aaactacatc
     1141 ggcaaaccgg cgcacaacct gttcgacatc cgcaccaacc tgcgttacgg ctgtaccatc
     1201 ctgcgccatt accggaatct tgaaaaaggc aacatcgtcc gcgcgcttgc ccgctttaac
     1261 ggcagcttgg gcagcaataa atatccgaac gccgttttgg gcgcgtggcg caaccgctgg
     1321 cagtggcgtt gattttgaac ccgcgccgca accgaaatac ggcgaatcct gtataatccg
     1381 aaaatctgtt cactggaagt tcagacggca ttgcaactgt tgatgccgtc tgaaaaaata
     1441 tgatggcaag agacaaccgc atccaaatgt ttccgcacga atggcgcgcc agtacgacgc
     1501 tttccggcgt gtacgcgctg cgtatgctgg gtatgttcct cgtgctgccc gtattggcgg
     1561 tgtatgccgc ctcgctgccc ggcgcggaag gcaacaaaac gctggtcggg ctggcaatgg
     1621 gcatttacgg gctgacacag gctctgctgc aactgccttt gggcatcgct tccgacaagt
     1681 tcgggcgcaa gaaaaccatt tatgcgggac tggtcgtgtt tgcggcgggc agctttcttg
     1741 ccgccgccgc cgatacgctg cccatgctgg tcgccgcacg cgccatacag ggtgcagggg
     1801 cggtcagtgc ggcggttacc gcgctgctgg cggatttgac gcgcgacggc gtacgtaccc
     1861 gcgcaatggc gatgatcggt ttgagtatcg gtttgacgtt ttcggtcagc ctcgtcgttg
     1921 cccccgtgat tgccgacgcg gtgggcgtac gcggcttgtt tctgctgacc ggtattttga
     1981 ccgttgccag tatcggcgtg gtggcgtgga tgactcccga cccggaggtt tccaagctgc
     2041 acgaagatac gcaggcgcag ccttcgcgca taggcgaagt tttgaaaaac cgtaggctgc
     2101 tgacgctcga tttcggcatt ttcgccctgc acgccgcgca aatggcattg tttaccgcgc
     2161 tgcctttcgc gatgacccag ctcggtttgg aaaaaatcca gcactggaaa gtctatctgc
     2221 cctcgaccat tacgggattg gtggtaatgg ttccgctgat tatcgtcggc gagacgcgca
     2281 acaagcttaa gcaggttttt gttttgggta tcgtctgtat tgcggcggcg cagctcggtt
     2341 tgctgtccgg tatgcgctcg gtaggcttga ttaccgctta tttggttgtt tactttatcg
     2401 gttttaatgt gttggaagcg agcctgccgt ctatggtttc caaaatcgcg ccgtccgacc
     2461 tgaagggtac ggcgatgggc gtgtacaaca cgatgcagtc gctcggactg tttgccggcg
     2521 gcgcggcagg cggtttgctg tttcaaaaat acggcttttc cggcgtgttt gccttttgca
     2581 gtatattgat gctgctgtgg ctggtaattg ccgttttatc gcccgcgccc aagcccgtca
     2641 aaaacctcag ttaccctgtc ggcggcgtgt ggcagggcaa tcaggacggc ttacaatgcg
     2701 ccttgtcgca actcgaaggc gtggaagaca tcggtttcag tttcgacagg cagaccgtct
     2761 atctcaaagt gttgcagaag ggtttcgatc aggctgccgc tgaaaaaatc atcacaggag
     2821 tttaaaaaat gtcattgaac aaagtcatcc ttatcggccg tctcggacga gatcctgaag
     2881 tacgctatat gcccaacggc gaagccgtct gcaatttcag cgtcgccacc agcgaaactt
     2941 ggaacgaccg caacggtcag cgcgtagagc gcaccgagtg gcacaacatc acgatgtacc
     3001 gcaaactggc ggaaattgcc gggcaatacc tcaaaaaagg cgggctggtt tatctggaag
     3061 gcagaatcca aagccgcaaa taccaaggca aagacggcat cgaacgcact gcttacgata
     3121 ttgtcgccaa cgaaatgaaa atgttgggcg ggcgcaatga aaacagcggc ggtgcgcctt
     3181 acgaggaagg ttacggtcag agtcaggagg cttaccaacg ccccgcgcag caaagccggc
     3241 agcccgcctc cgacgcgccg tcccatcccc aagaagcacc agccgcgccg cgccgccaac
     3301 ccgtgcctgc cgccgccccg gtcgaggaca ttgacgacga catcccgttc tgaattttac
     3361 ggcagcacat cctcgcggag ggaaatcata aaggacggag aaaccttaaa ccttacgggg
     3421 cagggtttct cttttttgca tttgtgccgg cttgttgctg ccccctgcgt tgggcggaac
     3481 gttgcgattg cgccgttctg gcgttttgag gcagtgatgc ctgccgcagg cccacgctgt
     3541 tttcagacgg tatagtggat taacaaaaat caggacaagg cgacgaagcc gcagacagta
     3601 caaatagtac ggaaccgatt cacttggtgc ttgagcacct tagagaatcg ttctctttga
     3661 gctaaggcga agcaacgctg tactggtttt tgttaatcca ctatatttta aaattcaggc
     3721 ggtgttttca aatagcgcga agcaatagcc gagcttcagc cggtttgttt gaaatcaaag
     3781 ggttggaatt aaacgccaaa cgcttgaacc attattgccc gatgcggcaa accggcatcg
     3841 tccggcaata cggttgttta aaaataggaa aatcaggatg gaaaaccaaa ggccgctcct
     3901 aggcttcgcg ttggcacttt tggcggcgat gacgtgggga acgctgccga ttgccgtgcg
     3961 gcaggtattg aagtttgtcg atgcgccgac gctggtgtgg gtgcgtttta ccgtggcggc
     4021 ggcggtattg tttgttttgc tggcactggg cgggcggctg ccgaagcggc gggatttttc
     4081 ttggtgctca ttcaggctgc tgctgctcgg cgtggcgggc atttcggcaa actttgtgct
     4141 gattgcccaa gggctgcatt atatttcgcc gaccacgacg caggttttgt ggcagatttc
     4201 gccgtttacg atgattgttg tcggtgtgtt ggtgtttaaa gaccggatga ctgccgctca
     4261 gaaaatcggc ttggttttgc tgcttgccgg tttgcttatg ttttttaacg ataaattcgg
     4321 cgagttgtcg ggtttgggcg cgtatgcgaa gggcgtgttg ctgtgtgcgg caggcagtat
     4381 ggcatgggtg tgttatgccg tggcgcaaaa gctgctgtcg gcgcaattcg ggccgcaaca
     4441 gattctgctg ttgatttatg cggcaagtgc cgccgtgttc ctgccgtttg ccgaaccggc
     4501 acacatcgga agtttggacg gtacgttggc gtgggtttgt tttgcgtatt gctgcttgaa
     4561 tacgttaatc ggttacggct cgttcggcga ggcgttgaaa cattgggagg cttccaaagt
     4621 cagcgcggta acaaccttgc tccccgtgtt taccgtaata ttttctttgc tcgggcatta
     4681 tgtgatgcct gatacttttg ccgcgccgga tatgaacggt ttgggttatg ttggcgcact
     4741 ggtcgtggtc gggggtgcgg ttacggcggc ggtgggggac aggctgttca aacgccgcta
     4801 gttcgcaggc aacggaaaat gccgtctgaa cgaggtttca gacggcattt tatttgaggg
     4861 aaagattagc gcggatgaac catatcggca ggaacgacca gttcgtcaaa ttcttcgccc
     4921 gtcagcaagc ccagctcaac ggcggtttcg cgcaacgatt tgttgttttt gtaggcggtt
     4981 ttggcgactt tggcggcgtt ttcgtaaccg attttgcggt tcaacgcggt aacgagcatc
     5041 agggaatggt gcaggaaata gtcgattttt tccggtacgg gttcgatgcc gacggcgcag
     5101 tgttcgttga agctgttgca cgcgtcgccc aagaggcgga tggattgcaa gaggttgtag
     5161 gcgataacgg gcatatagac gttcagctcg aaattgcccg acgcgcccgc cataccgatg
     5221 gtaacgtcgt tgccgaacac ttggcagcac accatcgtca ttgcttcgca ttgggtcggg
     5281 ttgactttgc ccggcatgat ggacgaaccc ggctcgtttt cggggatttt gatttcgccc
     5341 aaaccgcaac gcgggccgct tgccagccag cggatgtcgt tggcgatttt attcaggctt
     5401 gccgccagcg ttttcaatgc gcccgaagcg gcaacggcgg catcgcgtcc gcctaaggct
     5461 tcaaatttgt tcggcgcgct gacaaacggc aagccagaca gttcggcgag tttagcagca
     5521 gctttttcgg cgtattcggg atggctgttc aaacccgtgc cgaccgccgt accgcccaaa
     5581 gcaagttcat acaagtcttt aagcgcatcg ttcagacggc ctaaaccgtg atcaagctgg
     5641 gaaacgtagc cggaaaattc ctgtcccaaa gtcagcggcg tcgcgtcttg caagtgggtg
     5701 cggccgattt tgacgatagg ggcgaaagct tgggcttttt tgtccaacgt gtcgcgcagg
     5761 gcttttacgg cggggatgag gtggcggttg atttcaatcg cggcggcaac gtggatagcg
     5821 gtcgggaatg cgtcgttggt cgattgcgcg tggttcacat ggtcgttggg atggacgggc
     5881 tgataagccg ccaaacccgt accggcgatt tcgttggcgc ggtttgccag cacttcgttc
     5941 atgttcatat tggactgcgt gccggagccg gtctgccaaa ccactaaagg aaactgtccg
     6001 tcaagcctgc cgttcaacac atcatccgcc gcctgcgtaa tcaaatccgc ctgttccggc
     6061 ttaatcctgc cgagggaaac attggtcgcg gcggcggctt ttttcaccag cgccaaagca
     6121 taaatcagcg gctgcggcag ggtttcgccg ccgattttga aattgttgcg gctgcgctgg
     6181 gtctgcgcgc cccaataggc ttcggacggg acttcgacat tgcccatggt gtcatgttcg
     6241 gtacgggtgc tcatgcgttt ctccttttga aatgtgaata agagtgattc gcaaatatta
     6301 taatggagat tggcggaatg aggaagcatc aaggcgggag ggcaaaaaaa tgccgtctga
     6361 aaagcgttca gacggcattt gtttaggtgt ggggttacag cacggatttc accgtatcaa
     6421 ccacattgtc cacggtaaag ccgaatgctt tgaagagtaa atcggcaggg gcggattcgc
     6481 cgaagcggtt gatgccgacg actgcgccgt tcagtccgac atatttgtac cagccgtcgg
     6541 cgtggccggc ttctacggcg atgcgcggca ggctttcggg caggacggcg gcttgatagg
     6601 cggcgtcttg gcggtcgaat acgttggtgg acggcatgga aacgacgcgc acggcgatgt
     6661 tttgcgcggc gagggctttt tgcgcttcca aagccagctc gacttctgag ccggtggcaa
     6721 tgatgacggc ttgggcgttg ccttgggctt cgctgatgat gtagccgccg cgtttgatgt
     6781 cgtccagttg ttgttcgctg cgcgcttgga atttcaggtt ttgacggctg aaaatcaggc
     6841 aggacgggtg atcggcggct ttgacggctt ctgcccaagc gaccaaggat tcggcggtgt
     6901 cgcacggccg ccatacgtcc atattcggaa tcaggcgcag ggtggcggtt tgctcgatgg
     6961 gttggtgggt cggaccgtct tcgcccaaac cgatggaatc gtgggtgaac acaaatacag
     7021 ggttgatttt catcagtgcc gccatacgca gggcgttgcg ctcgtattcg ctgaacatca
     7081 ggaaggtcgc accgaatggt ttgatgccgc cgtgcagggc aagaccgttc ataatcgcac
     7141 ccataccgaa ctcgcgcacg ccgtagtgga tgtagttgcc gcctttgtcg cgggtaacgg
     7201 agacgctgtt tgaccagtcg gtcaggttgg acggggtcag gtcggccgaa ccgcccacca
     7261 attcaggcaa ctcttttgcc aagatttcga tgctgttttg gctggctttg cgggtagcga
     7321 tggtttcggc tttggcgcac acttctttca atgccgtctg aacgtattca tcgaaattgt
     7381 ccggcagctt tttatccata cggcgcacaa attctgcggc ttcggcagga tatttggctt
     7441 gatattgcgc gaacagttcg ttccagtcgg cttccagttt cgcgccttgt tctttggcat
     7501 tccacgcatc gtaaatttct tgcgggattt caaaggcggg gtaagtccag cccaaatgtt
     7561 tgcgcgtggc ttcgatttcg tccgcgccca aaggtgcgcc gtgggttttg tggctgcctt
     7621 ctttgttggc actgcctttg ccgattaagg ttttgcagca gatgatggac ggtttgccgg
     7681 tttcggcacg tgcggcttcg atggcggctt gaatggcggc ggtgtcatga ccgtttacgt
     7741 taggaacgac gtgccagccg tagctttcaa agcgttgcgg gatgttttcg gtaaaccagc
     7801 cgtccacttt accatcaatg gaaatattgt tatcgtcata caaaacaatc agtttgccca
     7861 agcctaaagt gccggcgagc gaacaggctt cgtgcgatac gccttccatc agacagccgt
     7921 cgcccatgaa gacgtaggtg taatgatcga cgatgttcaa accgtcttta ttaaattcgg
     7981 cggcaaggat tttttctgcc aatgccatac ccaccgcgtt ggcaatccct tgccccaacg
     8041 ggccggtcgt ggtttccacg ccgtcggtgt agccgtattc ggggtggccg ggggttttgc
     8101 tgtgcagctg gcggaagttt ttcaagtctt caatgctcag attgtagccg gtcaggtgca
     8161 gcaggctgta caacagcata gacgcgtggc cgttggagag gacgaagcgg tcgcggttgt
     8221 agaatttggg gttggcgggg ttgtgattga ggaatttcgt ccacaatgtt tccgccattt
     8281 ccgccatacc cataggcgcg ccggggtggc cggaattggc tttttgaacg gcatcggccg
     8341 agaggaagcg gattgcgttt gccagttgag acattttgta ttttccttgc tggtgtttca
     8401 gataagtgga taatcggaaa gcgttgatta tcgcccgatt cgcttatgct ttcaagaaaa
     8461 gggcggacgc gtgggaaggc ggcggcaggg gacaggcggg gaaggatttt cgatttgcgg
     8521 gcgaagcctg ccattattcc ttttgaaata aaaagttata gattgtgtgc cggattgtcg
     8581 atagcgtttg tttatgagct tgcgccgtcg gttctgccga tatgggggtg tcggtttttt
     8641 tagtcttttt tttaaccgta ttcggatttt gttcgggcgg taaggtaaaa tccaggcgtt
     8701 ttgatgcgga tgggaaatgt atccgcccca tacatccgga cggcgcataa agttgtacaa
     8761 tagcggaaat atattttggg aaaaacggat tttctcaaaa cttgaaacac aacgccttaa
     8821 aaaacaagaa aaatgacgtc tgaaaagcaa acggcggcgg taacgggcaa accatcaatc
     8881 aaaaatctaa ggaatgcaga atgaccacgg aaaaccaagc cggcagtccg gcatccggaa
     8941 tcggcacgtc cgaacaaaca aaagccgcgc cgaaagcaaa aaaaacattc gatccgcgag
     9001 ccagcgtgat tcaaatccat cccgaaggcg aacgcatcca tcccaaaaag gcggaaggac
     9061 ggttcgccaa actgcgtatc gccgccgtat tggcgacgca gtttgtgttt tacgtcattc
     9121 cgtggttcaa ctggagcggc aggcaggccg tcgttttcaa tatccccgaa cggcatttct
     9181 tcattttcgg attgtcgttg ggggtgggcg atttgattta ccttgccttg ctgctgatga
     9241 tttgcgcctt cgggctgttt tggtggacga cgattgcagg gcgactgtgg tgcggctatt
     9301 cctgcccgca aacggtttac accgaaatta tgctgtggat tgacaacctg gtcgaaggcg
     9361 atagaaacaa acggctgaaa ctggaaaaat cgccgtggaa tttcactaaa atccgcatca
     9421 aagccaccaa atacctgctg attttccttg tctgcgcgtg gacgggcatc acgtttgcag
     9481 gctggtttgt ccctatccgc cagttcgttc ccgatttatt cactggagca gcaggtggcg
     9541 gcgcgatgtt tgccgcagcg ttttatggct ttatgacctt cttcttcgcc cacattatgc
     9601 gtgaaaaagt atgcctgcat atgtgtccgt atgcacgttt ccaaagcgcg atgttcgaca
     9661 aggacacgct gattgtttct tatgacgcgg aacgcggcga accgcgcggc gcgcgcaaga
     9721 aaacggtcaa taaggaagag gcgggtttgg gcgactgcat caactgtgcg atgtgcgtcc
     9781 aagtctgccc cgtcggcatc gacatccgca acggtctgca ataccaatgt atcggctgcg
     9841 ccgcctgtat cgacgcgtgc gatgagatta tggacaaaat gggctatccg cgcggattaa
     9901 tccgttatac gaccgaaagc gcgctggaac acgaatattc tgaaaaagac attaaaaaac
     9961 ggctgctcag accgcgcgtg gcaggttacg gcgcggtgtt ggcgttagtt atcattgcct
    10021 tcctggccgg tttgtccacg cgcaaaatgg tcgaggtcga tattttgaaa gaccgtggcg
    10081 tactggtgcg cgaaaacgcc aaaggctggc tggaaaacgc atacagcctg cgtatcatca
    10141 acaaaagtga aaaagaacag ctcattaccg caagtgtcaa aggctttgac gaaatcgccc
    10201 tgaccgggct gcccgaaggc ggtatcaagg ttgccccgcg cgaaacggta acccttcccg
    10261 tccaagtgtc caccattccg gaatacgcgg acaaaggcag ccaccctatc gaatttacct
    10321 tccaataccg cgaaagcggc gcgcccgacg gcaagccggt cgtcttggaa gaagatgcaa
    10381 cctttatcgg agaataaccg tgtctcaaaa cactccaatc aaaccttggt acaaacacgt
    10441 ctggccgtgg atcttgatgg cggggccgat ttttgtcgtc atcgccagcg tcgctatgtt
    10501 ttttgtcgcg cagcagcacg cgacagattt ggttacggac gattattata aagacggcaa
    10561 acatatcgac atccagcttc atcgggatga agaagccgtc agacggcata tcggggtgca
    10621 ggttctcatt tcccccgata tgaatgcggc aaaagtgttt gtcggcggcg agtttgacgg
    10681 caaacagcct ttgaacctgc tgctgatgca cccgacccgc aaggcggacg atcaaaccgt
    10741 cgccctcaag cccgtcggca gcgcgcagaa cggcagggcg gaatatgagg cggtgttcaa
    10801 aaccctttcg ccgaccaacc actggtatgt gcgcgtggag gacgcggcag gcgtgtggcg
    10861 cgtcgagaac aaatggatta ccagccaagg caatgcggtg gatctgaccc cgatggataa
    10921 acttttcaat aatgccggaa gcaaataaaa aagccgtgtt ttcattgcat tggtttgcca
    10981 gatgcaatgt cgggcaggca ttgtttgatt attcggcgtg atggtctgat ttatcggacg
    11041 aaaataaatg tatcttatcc cgtttatttt ttaacaccat tccgaaatgc agcctgaaaa
    11101 atgccgtctg aagggcttca gacggcattt gtgttgtatg cccgacacaa tgcggaaggc
    11161 gttttgttta cataaaaacg tttttatttc tctccgtttt ttcgacacta ttccgaaacg
    11221 cagcctgaaa aatgccgtct gaaaggcttc agacggcatt ttgtttgcaa atcaaatcct
    11281 acctgatgtc agcgtccgag cgttgcaaca ggttcgctcc ccgtcagcag atattgtatc
    11341 gtctcgcgga cggtgcggat ggcattgccg aagggcagcg ggtctttacc tctgaagaac
    11401 aggcctttat ctacttctcc acggaatgcg gcggcaagct ggatatcaat gcagaattgt
    11461 ccggctttgg aaagcccgtc gcgcagaccg caactggtca ggcagtttaa accttgggta
    11521 cagcggcgcg ggtcagcttt ggcgtttgcc tgaagtttgc tttcacgctt gatgtagctg
    11581 tctaggaatt tggtgcggac accgcgcgcc ggcaaaccgg caacagacat aaattcaact
    11641 actttttcag tttccgcacc ggcgagcgtt tttttgaagt taaggtgtgc atctccttct
    11701 tcggtaacgg caaaagccgt accgatttga acggcggatg ctccccagtt ctttagggcg
    11761 gttttgactt tttcaaaatt tgccatgcct cccgcaagaa taagcgggat tttttcgctt
    11821 tccagcccta aacttttgaa aacttcaaac gtttcctcaa tcacgcgttt gaagtcgaac
    11881 ttggcatcgt ttacgccttc aacggttgat gcacccaaat gtccggccgc gtgggcagga
    11941 tgttcgacta caatcgcatc gggcaatatg ccttttttca tccaacgttt caagacgata
    12001 ttaataccgc gcgattcgga cagaatcggc agcagcgcga catctttatg atagccctcg
    12061 gtcatttccg gcaggtctaa aggcaggccg gcacccatta caaccgcatc cgcccctgat
    12121 tcgcaagcct ggcggacata cgcggcgtgg tctttgaccg ccttcatcac gttgaccgca
    12181 atcagtcctt ttccctctga agcgcttttg gctttttgga tttccctgtc taatgcggta
    12241 cagttcaaag atgtatattt ctcttcactc ggattgattt gtgattcggc gagtaggtct
    12301 tcgtgaaggt ggcgcaaatc cacactggca atcgttccga taccgttttc acgtgccacc
    12361 gcgctggata aacccgatgc ggaaacaccg acccccatac cgccttgcac gatgggggta
    12421 agggattttc cacgaataac caaagggtca aaaatatttt gcatcagttt ctccgagtat
    12481 acgaatcagt caggctcatg aaaaatggtt ctaactgttt tagaactatt gctcaaattt
    12541 ggtattatac tctaaatatc gcggcggtaa acaagaaagc agccggagct tcgggcatat
    12601 tctgttacgc ctgtttcaat cgggagagaa aatattatag tgaattaaca aaaatcagga
    12661 caaggcgacg aagccgcaga cagtacaaat agtacggcaa ggcgaggcaa cgccgtactg
    12721 gtttaaagtt aatccactat aaatttgatg atggcataaa aaagccctag tcagttgctg
    12781 tcaaagggga ttgttaagaa aagtaatgcc acgttgatgg ggtgcaatat atcaggcgtt
    12841 tcaatcgggt aaaatgttgg acggacaccg catctggtta tgggatatcg gtttgcacgg
    12901 caaaggtttg aatatgattc gattgtgtct gagattctga tgaagggggt aggtaaagat
    12961 atggtaacga gttgccgaga caataaaaaa tccccgaggg ataatctcgg ggatttggaa
    13021 tttggcacgc ccacggggaa tcgaaccccg gttaccgccg tgaaagggcg atgtcctaac
    13081 cgctagacga tgggcgcata ttgtattttc ttactggtgc acccggagcg attcgaacgc
    13141 ccgaccctct ggttcgtagc cagatactct atccaactga gctacgggtg cgctgcaaga
    13201 aagatttgaa ttttagggta atcatcggat tctgtcaatt gttttgttgg atgaaatgcc
    13261 ttaaaagtgt aaaatatcgg tttgttgttt gaatttaaag agaataaaat gattgttgct
    13321 tcccgctggc ccttgctgga aaaggtattt ttacggtttg gaatgccggt tgccgtggtc
    13381 gatttggaat cgacgggcgg caatctgtat gaagacaggg taaccgaagt ggctttggtc
    13441 aagtttgagc agggaagggt ggtgaggcat gagtggttgg ttaatcctca aaaaccgatt
    13501 ccgcagtttg tggcggggct gacggggatt tcagacggca tggttgccga tgcgcctgtt
    13561 tttgcagaga ttgccggcga gttgttttcg gtattgaagg gttgtgtgct ggttgcacat
    13621 aacagccgtt tcgactatac gtttttaaag catgagtttc atcgtgcggg tatcggattt
    13681 tcatcgcctg ctttgtgcag tgtgcagctg tcccggtgtc tgtatccgca attttacaag
    13741 cacagcctgg acagtatcat cgaaaggttg gggattgttg tggaagacag gcatcgtgcg
    13801 atggcggatg tgtcggcgtt gtgtgattat ttggaataca gcctgtcgga acacggggtc
    13861 gaggagtgga tcaggcagtg tttccgtttg atgaatccga aaccgttgcc tgccgcgctg
    13921 cccgaacggt tgagggaaca gttgtacggt ttgcctgacg gtatgggggt gctggcctgt
    13981 ttcgacggcg gagggaaagt aaattacatc ggtacgtttg aacgggtata tagcgaggtt
    14041 tcggctttat tggactccgg aaaagccccg tttgattggt gcaatacgga ggaagtccgt
    14101 ttttttcccg cattgggcag gctgcatgcc cataaggtta aagcggaatt ggtcaggcat
    14161 tatggggtgg attgttacgt atctgccaaa aatctgctta aaacatttac gaccgtcagg
    14221 tttgaaaaag gttcagacgg catattgaat gcgaaaacag cagatttaaa aaacggtgtg
    14281 acggataatc cgcctaccgg attatttgcc aataaaaagg cggcgagacg ggctttgtcg
    14341 tcgtgggcgg aaacatacgg attgtgtcct gccgcagccg gtatcctgcc ggacggttat
    14401 gcagaggatg agccttgtcc cgtatatgtt tcaggccgat gcgataaggc gtgcggccgt
    14461 tctgacgaac aggttttggc gtttgcacac aagttgcctg ttttggattg gggaaaaatg
    14521 catgaggtgg aaattaccga aaccgatcct ttaacggggg aaaaagttgt tctgcatgga
    14581 atgggcggcg cattggaaat ggatgacggg ctttggtatt tcgataaaga tttaccggat
    14641 gcgtttaagg cgaagtttaa aacggacagg aaaaatatta aggaaatcgg ttaaatcgat
    14701 atcggttggt gaaagccggt aagtatgtaa acagccgttc gtattgattg cctaatcggt
    14761 ttgggttgga atatgttgcc gtttgtatgt atccgaaaat gccgtctgaa ggcttcagac
    14821 ggcatttttg ccgacgcggt tttcgtgccg tgtcggtttg accgtccatc cgaaggcatc
    14881 ggacaagcag ggtggttttt agaagccgtt ttccatcatg atttgaccgg gaatgcggtt
    14941 gcggtgcatg gcgtaaccca tgtcaagcag cgtttggaaa gtatctttga ccatttccgg
    15001 gttgccgcaa atcataaacc gtgtggattc cggggtgaac ttggtatgca gcgcctgttc
    15061 gatgctgctg ttttttaaga gttccggaat gcgttttccg cttaagcccg aggggttggc
    15121 ggcacgggtg gtaacaggga cgaaatggaa cgagtgtctg tattcgccta ccaggggatg
    15181 ttcggacaat gcggcgagcc ggtcgttgaa aatcaattct tcgggaaaag atacggaatg
    15241 tatcaggttg acggtatcga aacgctgtcg gatttcaggt tgttcgagaa tggaaaggaa
    15301 gggggcgatg ccggagccgg tgcagagcat caccaaatcc ttgccgtcgg ggaagcgttc
    15361 gggcaggagg aagccggtgg catttttatc gagcaggatg gtgtcgccct gttgcatttt
    15421 ggcgaaacgg gccgacatgg ggccgtcttg gatgagtacg gcaaaatatt cgagcgtgtc
    15481 tgcatattct gcggaaacga tggagtagga acgccaaata aagccttccc cttcgtagaa
    15541 accgagtcgg gagaactgtc cggctttaaa acggtaggat tcgggacggc tgatggcgaa
    15601 agtgatgagt ttcggcgtgt ggtgtttgac ccacaaaatc ttttcttcag tgaattttgc
    15661 ttcgggcgag gctgccatgt tgttgtcctt gagtgtgttt gtcgggatta tagccaattt
    15721 gggtgttttt ttccgcattg acgatctgta tttaaattcg gatatttttc aatacaatat
    15781 tatcgttttt tgaaataaac ggtaaggagc agtttgtttt ttgtcaaaat gggaatacaa
    15841 tcccatctat aaatttaatt gagaattact ttttttcaat taatataaaa aatcaaaaca
    15901 gttgtgaggg cctttggacg atttgcacac ttgcatatta cagaggtctc tatgaatcaa
    15961 aatcattttt cacttaaaat tctgaccgtt atgctgttat cggcttacgg tggttctttt
    16021 gcagacggtg ttgtgcctgt ttcagacggc aataccgtca gtctggatac ggtcaatgta
    16081 cgcggctctc atgctctgtc gggcaagacc gagaagaccc gttcttatac gatagatcgg
    16141 atgtccaccg ccacaggtat gaggattgcg ggcaaggata cgccgcagtc ggtcagcgtc
    16201 atcacgcgca gccgccttga cgataaggcg gtgcatacgc ttgaagaggc aatgaaaaac
    16261 acgacgggtg tcaacgttgt gcgcgattca ggcttgcaga cgcggttttt gtcacgcggt
    16321 ttctatattg atcagattgg tgaagacggt attaccgtca atgttgcagg ccgttcggga
    16381 tatacggcga aaatcgacgt gtctccgagt accgatttgg cggtttatga ccatattgaa
    16441 gttgtacggg gtgcaacggg gttgacccaa tccaattcag agccgggtgg aaccgtcaat
    16501 ttgatccgta agcgacctac cgcttctttc aaacataccg gagagctgac cgccgaccat
    16561 cgcggcagcc ggcgtgcagt gttggatgtt tcaggcagcc tgaataaggc gaatacctta
    16621 cgcggaaggt tggtgggtgc ggaagagtat aaaaaatcgt ttaaagaccg cgtttggggc
    16681 aggaaacata tggtttacgg cattgccgaa gccgatgcgg gcgacagcag tgtgcttact
    16741 ttgggcggca tgtatcagaa gagtagggag gttcctgatt tttcgggcat tattttgtcc
    16801 tgtgaaaatc agaaaactgc cccgttcagt tcaacgcctg cctgcaaccg gcctttgcaa
    16861 ctgccgcgca acacttattt gggggaggat tggtcgcggt tgagtgctga caaatacaac
    16921 cttttctcag gtttcaaaca tgtgtttgac aacggttggc agctcaatgc cgaagtgtct
    16981 tataccaaga atgaatccga tgcgaaggtg gggcagtttt ttctgaaaaa cgaacatgcg
    17041 gcgggtttgt cagatgagga tgcggtaggc tttttgaccg aaaaaaacga agtcatcccg
    17101 ttcgagccga aagataaggc attggagaaa ctgaaagcat atcgtgacga aaccgccaag
    17161 gaataccgtg agcgcaaaga cgattttgtt aaaaaccgtt tcgataatac tgctttcgag
    17221 cagtaccgca gccgccgtgc cgcagaacgc aaagccggtt ttgacgagtg tatgagtgcc
    17281 ccttttgcgc tggactttat ctgtcaaggt tcttgggggg atccgggtgt tgatgccgac
    17341 aagtcggaat ttgtcgataa agcccttgcg aaggaaggca tctttaataa tgcggcacaa
    17401 cgttttccaa acagcctgta tgactcttcc tttaatcgga aggctaccgc caaccgacga
    17461 tacagttata tgccgttgcg gcataccaaa gacgaccgcc aatggggaat taaacttgac
    17521 ctgaccggca catatgggct gttcgggcgg gagcatgatt tctttgtcgg ctatgcctac
    17581 ggcgatgaaa agatacgttc cgaatatctg gaaatctacg aacgccgcca cagagtacgt
    17641 ccgaatacag gggcaacgca cggcgtgtat gcgggaagtt gtcaggggag ccggacggtg
    17701 atttgtcttc tcctttggtc agggggcata aagaacccga ttggcaggcg tacgatgaaa
    17761 aaggcaaccg taccgtttat gccgaagaat gcaggaatgc caagaaaata aaaaccgagc
    17821 ccaagctcga tgccgaaggc aagcaggtgt attactatga cgaatacagc ggcagccgga
    17881 caccggtata tgtcgatgta tatgagctgg acgaaaaagg caacaagatt caggagacca
    17941 atcccgacgg ctcgcctgtc tttaccggtt tttccggtac ggtgccggtt tggaaaactg
    18001 ttaaagtggc cgatgaccat gttcctgcgc tgtataacta cgccaaatac ctcaacacca
    18061 acaaaaccca ttcgctgact gccagcacgc gtttcaacgt aaccggccga ctgcaccttt
    18121 tgggcgggct gcactacacg cgctatgaaa cctcgcaaac caaagatatg cctgtccgct
    18181 atgggcagcc ggcaagcgat tttcagacag catcgagtat taaggcggat caggaccatt
    18241 acacggccaa gatgcaaggt cataaattga cgccctatgc aggcatcacc tatgacttga
    18301 caccgcaaca gagtatttac ggaagttata ccaaaatctt caaacagcag gataatgtcg
    18361 atgtcagtgc caaaaccgtt ttgccgcctt tggtcggcac aaactatgag gtaggctgga
    18421 aaggcgcatt cttgcaagga cggctgaatg cttcgttcgc attgttttac ctcgaacaga
    18481 aaaaccgcac ggtcgtcgat tttggctatg ttcccggagc aggcggcaag caggggtcgt
    18541 tccaaaccgt tgccaaaccg ataggcaaag tggtcagccg tggggcggag gccgagttgt
    18601 cgggtgagtt gaacgaagat tggaaagtct ttgcgggtta cacctacaac aagagccgct
    18661 acaaaaacgc cgccgaagtc aacgccgaac gcctcgccaa aaacacaggc gcagacccgt
    18721 acaacttcag caatttcaca cccgtgcaca tattccgttt cggaacgagc ttccatatac
    18781 cgaatacggg gctgaccgtc ggcggcggcg tgtccgcaca aagcggcaca agcagcctgt
    18841 acaacatcag gcagggcggc tacgggctga tagacggttt cgtccgttac gaattgggca
    18901 aacacgctaa attgagcctc atcggtacga acttaaacgg acgcacttat tttgagaaca
    18961 actacaaccg tacgcgcggc gcaaacaact tctatggaga accgcgcact gtcagcatga
    19021 aactggattg gcagttttaa ttgaaaaccg tagttttgcg gatgccgtct gaaacagggt
    19081 atgtttcaga cggcattttt atggaggcag gcctatcggg gcgtatattt ggaatttgcc
    19141 cgatgccggc agtagaatat cccttttatc ctcagaagag ccgatgtctt cacgcaaaat
    19201 tatccacatc gacatggacg cattctacgc atcggtagag ctgcgcgaac agccgcattt
    19261 gaaagggcgg ccggtggtcg tcgcgtggga gggcgcgcgt tcggtgattt gcgccgcatc
    19321 gtatgaggca cggcagttcg ggctgcattc cgcgatgtcg gtggcaacgg cgaaaaggct
    19381 gtgtccgcaa gcggtgtatg tgccgccgca tttcgatttg taccgtcagg tttccgcgca
    19441 gattcacgcc gtattcaggc gttataccga tttaatcgaa cccttgtcgc tggacgaagc
    19501 ctatcttgac gttacccgta atttcaaaaa catcccttac gacagtgaag ttgccaaaga
    19561 aatccgtgcc gccatttttg cggaaacggg tttgaccgca tccgcgggca tcgcgtcgaa
    19621 caaatttctg gcgaaaatcg cgtcggactg gcgcaagccg aacgggcagt ttgtgttgcc
    19681 gccgcacaaa gtcatggcat ttttggaaac cctgcctttg ggcaaaatcc ccggcgtggg
    19741 caaggtaacg ctgaaaaaaa tgcagtcgct gggtatgcag acggcgggtg atttgcgccg
    19801 tttcgagcgc ggcgagctct taaaccattt cggacgctac ggctaccgcc tctatgattt
    19861 ggcgcgcggt acggacgaac gccccgtcaa agccgaacgc gaacgcctcc aaatctccac
    19921 agaaatcacc ctgcccgaag acctgccgct cgagcaggct gccggacact tgccccatct
    19981 tgccgaagac ttgtggcggc aaatcacgcg caaaaacgtc gaagcccaaa gtgtaacgct
    20041 caagctgaag acctacgatt tccgcatcat cacgcgcacg ctgacttatt cctccgtatt
    20101 gcccgactgc gcctccctgc ttcaggcggc gcaaatgttg atggcgcgcg tcccgccgca
    20161 gacggaagac gcgttccgcc ttatcggtat cggcgtgggg catcttgtgc cgaaaaacca
    20221 gcagcaggat ttgtgggcgt aaaccgcttt acgcgcgccg tccaaaaaat atgccgtctg
    20281 aagccttcag acggcattgc ggctccggtt taatccgccg cgccgctttt ttttaggttg
    20341 tcgagccttc cgattatatc ggcaaggttg cgcctgcctt cttccttgct gacaatcggt
    20401 tcgccgcctt tgcgccccag gattttcaaa tcttcctgcg gcatttcgtc tatgaatcgg
    20461 ctgggttcgg ggaactgcca tatgccttgt tttttgcgtt tgacgcagtg ggtcagcgta
    20521 agctggcgtt tggcgcgggt gatgccgacg tacatcaggc ggcgttcttc ttcgacgttg
    20581 ccctcttcga tgctgtcgtt gtgcggcaaa acaccttctt cgcaaccgac aaggaaaaca
    20641 tacggatact ccaaaccttt ggcggcgtgt agcgtggata gcgagacagc atcggtttct
    20701 tcttcgtctt ttccttccaa aagcgtcatc aaggcgacgg tttgggcgag ttcgatgacg
    20761 tttttgccgt cttccccgcc ttttcgcgca aaccatgata ccaaatcgcc gacgttgcgc
    20821 catttgattt cgcctgcttt gctttcttca ctggcaagca gatggttttc gtagtcgatt
    20881 tctttaagca ggttgttgat gaactcgcct gcttcgccgg tttccgcttt ggcgcggtag
    20941 ctgccgaaca tatccataaa ggcttgcagg tgttggcggt tggtattgtt cagcgtggca
    21001 agggcttctt cgttttgtgc ggcttcatac aggctgcatt cgtgttcgtg cgcgtaagtg
    21061 ttgagcttgc ccagcgtgac atcgccgatg ccgcgtttgg gcgtggtaac ggcacgcaga
    21121 aaggcgggat cgtcgttggg gttggcaagc agccgcacat aagacaacac gtctttgatt
    21181 tcggctttat cgaaaaagct ttgtccgccg gagagacggt aggggatgcg cgcgccgcgc
    21241 aatgcttcct cgaaaatcct cgcctgatgc tttccgcggt ataacacggc gaaatcggcg
    21301 tattgggttt tgtcgccgcc gatgagtttt tgtttgacga tttggctgac gacccagtcg
    21361 gcttcgtgct gctcgttttg gcaggcaacg actttgacgg gatcgccttc gccgaactgc
    21421 gaccaaagtt ttttggtgaa caattttgga ttgttttcaa tgactttgtt ggcgattttg
    21481 agaatccgcg cagtggagcg gtagttttgc tccagtttaa tgaccttcat ctgcggatag
    21541 ttttcctgca ttttgcgcag gttttccatg tttgcgccgc gccatgcgta gatggactgg
    21601 tcgtcgtcgc cgacggcggt aaacatacct tccgcgccgg tcagaagttt catcaacgta
    21661 aattggcagg tattcgtatc ttggcattcg tcaaccagca gataacgcag ccgccgctgc
    21721 catttgttgc gcacttcgct gttttgctgc aacagcacgg caggcaggcg gattaagtcg
    21781 tcgaagtcca ctgcctgata gctttgtaag gtttcctgat agctcgcata caggcgtgcg
    21841 gtttgttgtt cccacgcatt agaggccgtc tgaacgacat cttcaggcgt ttttaaatcg
    21901 tttttccaaa gggaaatttg atgttgcgcc ttgaatacgg cttctttgcc cgtaccgcct
    21961 aagagttcgc cgatgatttt cgcgctgtcg gtagaatcga gaatggagaa gttttttttg
    22021 taaccgatat ggttcgcctc ttcgcgcaga atcttcatgc ccaaagagtg gaacgtgcaa
    22081 atcgtcagcc cgcgcgtttg cggtttgggc agcattttgg cgacgcgctc ctgcatttcc
    22141 gcggcggctt tgttggtaaa ggtaattgcg gcaacggtat gcggcaggta gccgacattg
    22201 acaatcaaat gcttaatttt ttgagtaatc acgccggttt tgccgctgcc tgcaccggca
    22261 aggacgagca gtgggccgcc gaggtagcgg acggcttcga gctgttgggg attgagtttc
    22321 atcatgtttt gatgctgtct gaaatcagtc tgcgccgttt tcgaggcagt cgagtgtcgc
    22381 acggagggcg gatacgccga tttgccccgg cgcggagttt tgcgttcccg aaccgaacgt
    22441 gatgcttgag ccgaacacct gtccggcaag ccggctgacc gcccccgtct gccccatcga
    22501 catcgtaaca atcggtttgg cggcaagctc tttcgctttg agcgtggcgg aaagcaaagt
    22561 cagcacatct tccgcgcttt gcggcatcac cgcaattttg cagatgtccg cgccgcagtc
    22621 ctccatctgt ttcagacggc atacgatttc ttcttgcggc ggcgtgcggt gaaactcatg
    22681 attgcagagc agggcggcga tgccgttttt ttgagcattt gccacggcgc accggacggc
    22741 ggtttcgccg gaaaacagct caatatcgat aatgtcgggc aggcggcttt cgatcagcgc
    22801 gtcgagcagt tcaaaataat aatcgtccga acacgggaat gagccgcctt cgccatgccg
    22861 tctgaacgta aacagcagcg gtttgtcggg cagcgcgtcg cggacggtct gcgtgtggcg
    22921 caatacttcg ccgatgctgc ccgcgcattc caaaaaatcg gcgcggaact cgacgatatc
    22981 gaagggcagg tttttgattt ggtcaagtac ggcggaaagt acggcggcat cgcgggcgac
    23041 aagcggcacg gcgattttgg tgcgtccgct tccgataacg gtatttttga caacaaggca
    23101 ggaacacata aaacaggcac acacagaaaa aacagccgcc attataacaa agccggccgc
    23161 cttttagacg gcatccagat tccattccgg cacaagccgc cgcgtcctgc cgcatatcgg
    23221 caagcaagga aatatgcgat aatggcaacc ccgtgaagca gcattaccga tagcccgcac
    23281 atcgggaaaa cgatacacat cccgcgccgc agcccgtgtt gcgccgcatc ccacataccg
    23341 catttgttcc ggagtaaccc caatgtcaga cgacaaaagc aaagcccttg ccgccgcact
    23401 ggcgcaaatc gaaaaaagtt tcggcaaagg tgccatcatg aaaatggacg gcagccagca
    23461 ggaagaaaac ctcgaagtca tttccaccgg atcgctcgga ttagacctcg ccctcggagt
    23521 cggcggtctg ccgcgcgggc gcatcgtcga aatcttcggc cccgaatcct ccggcaaaac
    23581 caccctctgc ctcgaagccg tcgcccaatg ccagaaaaac ggcggcgtgt gcgcctttgt
    23641 cgatgccgaa cacgccttcg atcccgttta cgcccgcaaa ctcggcgtaa aagtcgaaga
    23701 gctttacctc tcccagcccg ataccggcga acaggctttg gaaatctgcg acacactcgt
    23761 ccgttcaggc ggcatagata tggtagtcgt cgattccgta gccgcactcg tccccaaagc
    23821 cgaaatcgaa ggcgatatgg gggacagcca tgtcggactg caggcgcgcc tgatgagtca
    23881 ggctttgcgt aaactgaccg gacacatcaa aaaaaccaac acgctggttg tgttcatcaa
    23941 ccaaatccgg atgaagatcg gcgtaatgtt cggcagcccc gaaaccacca ccggcggcaa
    24001 cgcgctgaaa ttctattctt ccgtccgcct cgacatccgc cgcaccggat ccatcaaaaa
    24061 aggcgaagag gtattgggca acgaaacccg cgtcaaagtc atcaaaaaca aagtcgcccc
    24121 cccgttccgt caggcagagt ttgacatcct ctacggagaa ggcatcagtt gggaaggcga
    24181 attgatcgac atcggcgtga aaaacgacat tatcaacaaa tccggcgcgt ggtacagcta
    24241 caacggcgcg aaaatcggtc agggcaaaga caacgtccgc gtctggctga aagaaaaccc
    24301 cgaaattgcc gacgaaatcg acgcaaaaat ccgcgccctc aacggcgtag aaatgcacat
    24361 caccgaaggg acgcaggacg aaaccgacgg cgagcgtccc gaagagtaaa acttgaaatc
    24421 ccgataaacg gtactcctgc tgcgaagtac cgttttttga gctgcctccg aacggcttga
    24481 tttgagtttt ggtatagtgg attaacaaaa atcaggacaa ggcgacgaag ccgcagacag
    24541 tacaaatagt acggaaccga ttcacttggt gcttgagtac cttagagaat cgttctcttt
    24601 gagctaaggc gaggcaacgc cgtactggtt tttgttaatc cactatattt ttgcccgacg
    24661 gggtgaaaaa tacagttgct acagcccgac ctacgcccgc tttgcctcta tcctgcgccc
    24721 ttttatgtgc aacactttgc acttgctgaa caaaattcaa acgacccttt atatcaaatg
    24781 caaaaaatat gccgtcattc ccgcgaacgc gggaatccag acccctcggc atggaaattt
    24841 atcgagtaaa acggtttctc agattctacg ttctagattc ccgcgttcgc gggaatgacg
    24901 gcggcggggg gttctgtttt tttccgatag attcctgtgg tttttcggtt actggattcc
    24961 cgcttttgcg ggaatgacgg ggtgtaagtt tctgctccca cggggctgga ttcccgtttt
    25021 cacgggaatg acgaaatttc agacggcatc ggaatttttg tgttttggtg ggcttcagcc
    25081 tgccgcatcc catcgattct gccgttttta ccgtttccgc cgaatcctgc aaactgatgc
    25141 cgtcattccc gcgaaggcgg gaatccagac ctgtcggcac ggaaatttat cgagtaaaac
    25201 ggtttct
//
LOCUS       DAXISH010000025        24080 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.025, whole genome shotgun sequence.
ACCESSION   DAXISH010000025 DAXISH010000000
VERSION     DAXISH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 24080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24080
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.025"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(744..1886)
                     /locus_tag="ACFOV4_001034"
     CDS             complement(744..1886)
                     /locus_tag="ACFOV4_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFC7619060.1"
                     /translation="MKKSVLAVLAALSLAACGGSEKNAVQPQADAASAANAEAAATDT
                     LNIYNWSNYVDESTVEDFKKANNLKLTYDLYENNETLEAKMLTGKSGYDLVVPGIAFL
                     PRQIEAGAYQKVNKDLIPNYKNIDPELLKMLETADPGNQYAVPYFSGVNTIAITAKGK
                     ELLGGKLPENGWDLLFKPEYTHKLKSCGIALWDTPSEMFPILLNYLGKDPKGSNPEDL
                     KAAAEVLKSIRPDVKRFSPSIIDELARGDICLAAGNGGDLNLAKARSEEVKNNVGIEV
                     LNPKGMGFWIESWLIPADAKNVANAHKYINYTLDPEIAAKNGIAVTFAPASKPAREKM
                     PAELVNTRSIFPNEQDMKDGFVMPQMSTDAKKLSVSLWQKIKVGTN"
     gene            2190..2453
                     /gene="rpsT"
                     /locus_tag="ACFOV4_001035"
     CDS             2190..2453
                     /gene="rpsT"
                     /locus_tag="ACFOV4_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFC7619061.1"
                     /translation="MANSAQARKRARQSVKQRAHNASLRTAFRTAVKKVLKAVEAGDK
                     AAAQAVYQESVKVIDRIADKGVFHKNKAARHKSRLSAKVKALA"
     gene            2613..3761
                     /locus_tag="ACFOV4_001036"
     CDS             2613..3761
                     /locus_tag="ACFOV4_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HFC7619062.1"
                     /translation="MPTMGAEMNTRNMRYILLTGLLPTVSAFGETALQCAALTDNVTR
                     LACYDRIFAAQLPSSAGQEGQESKAVLNLTETVRSSLDKGEAVIVVEKGGDALPADSA
                     GETADIYTPLSLMYDLDKNDLRGLLGVREHNPMYLMPLWYNNSPNYAPGSPTRGTTVQ
                     EKFGQQKRAETKLQVSFKSKIAEDLFKTRADLWFGYTQRSDWQIYNQGRKSAPFRNTD
                     YKPEIFLTQPVKADLPFGGRLRMLGAGFVHQSNGQSRPESRSWNRIYAMAGMEWGKLT
                     VIPRVWVRAFDQSGDKNDNPDIADYMGYGDVKLQYRLNDRQNVYSVLRYNPKTGYGAI
                     EAAYTFPIKGKLKGVVRGFHGYGESLIDYNHKQNGIGIGLMFNDLDGI"
     gene            3904..4605
                     /locus_tag="ACFOV4_001037"
     CDS             3904..4605
                     /locus_tag="ACFOV4_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF502 domain-containing protein"
                     /protein_id="HFC7619063.1"
                     /translation="MTEPEAEGGKAAKALKKYLITGILVWLPIAVTVWVVSYIVSASD
                     QLVNLLPKQWRPQYVLGFNIPGLGVIVAIAVLFVTGLFAANVLGRQILAAWDSLLGRI
                     PVVKSIYSSVKKVSESLLSDSSRSFKTPVLVPFPQSGIWTIAFVSGQVSNAVKAALPK
                     DGDYLSVYVPTTPNPTGGYYIMVKKSDVRELDMSVDEALKYVISLGMVIPDDLPVKTL
                     AGPMPSEKADLPEQQ"
     gene            4663..6471
                     /gene="aspS"
                     /locus_tag="ACFOV4_001038"
     CDS             4663..6471
                     /gene="aspS"
                     /locus_tag="ACFOV4_001038"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFC7619064.1"
                     /translation="MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGI
                     VQVVIDPDTPEAFAAADSARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVL
                     NAAATPPFQIDDENISENVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFID
                     IETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFR
                     DEDLRADRQPEFTQIDLETSFLNEDEIMDITEGMAKQVFKDALGVDLGDFPRMPYSEA
                     MFYYGSDKPDMRINLKFTELTDLMKTEEFKVFRGAADMKGGRVVALRVPNGAKFSRKE
                     IDEYTKFVGIYGAKGLAYIKVNDVGNLSNGEDSGLQSPIVKFLSENALKEIIARTGAQ
                     NGDIIFFGADKTKVVNEAIGALRIKVGLEHGAENGYFTDEWKPLWVVDFPMFEYDEEA
                     DRYVAVHHPFTAPKEGHEDLMVSDPANCLARAYDMVLNGWEIGGGSIRIHRADVQEKV
                     FAALKISPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDVIAFPKT
                     QRAQCLLTNAPNSVDDKQLRELSLRLRQKAAETKEA"
     gene            6622..6906
                     /locus_tag="ACFOV4_001039"
     CDS             6622..6906
                     /locus_tag="ACFOV4_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFC7619065.1"
                     /translation="MKKLLLAAVVSLSAATAFAGDSAERQIYGDPHFEQNRTKAVKML
                     EQRGYQVHDVDADDHWGKPVLEVEAYKDGREYDIVLSYPDLKIIKEQLDR"
     gene            7073..8965
                     /gene="speA"
                     /locus_tag="ACFOV4_001040"
     CDS             7073..8965
                     /gene="speA"
                     /locus_tag="ACFOV4_001040"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008792 - arginine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HFC7619066.1"
                     /translation="MPILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQTVSLQ
                     KLTEAVQQKHQARLPVLFCFPQILEHRLRDINRAFQTAREECGYKGGYCLVYPIKVNQ
                     HRRVIESLMSSGQPHGLEAGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEK
                     LGHQVYLVIEKLSEIQMVLEEAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLS
                     ASQVLQLVDILKQKNRLDCLQLLHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNI
                     RCFDVGGGLGVDYEGNRTQSDCSVNYSLNEYAATVVWGISQACLEHGLPHPTIITESG
                     RGITAHHAVLVANVIGVERYKPRRLDAPSPEAPRVLHSMWETWTDISASREKRSLRSW
                     IHEGQFDLADVHNQYNVGLLSLAQRAWAEQLYLNICHEVGELFNEKHRSHRTIIDELQ
                     ERFADKLYVNFSLFQSLPDAWGIDQLFPVCPITGLNEPIARRAVLLDITCDSDGTIDH
                     YIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAYQEILGNMHNLFGDTATADVVVGEDGQ
                     FTVIDYDEGNTVADMLEYVYQDPKELMKRYREQIEHSDLPASQAMSFLKELEAGLNGY
                     TYLEDE"
     gene            9064..9987
                     /gene="speB"
                     /locus_tag="ACFOV4_001041"
     CDS             9064..9987
                     /gene="speB"
                     /locus_tag="ACFOV4_001041"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HFC7619067.1"
                     /translation="MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPY
                     DMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRD
                     FVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNG
                     SEYDHGTMFYTAPKEGIIDPAHSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKI
                     KETVGNMPVYLTFDIDCLDPSFAPGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVE
                     VAPSYDQSDITALAGATIALEMLYLQGAKKD"
     gene            10185..11651
                     /locus_tag="ACFOV4_001042"
     CDS             10185..11651
                     /locus_tag="ACFOV4_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008509 - monoatomic anion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006820 - monoatomic anion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HFC7619068.1"
                     /translation="MMKLGFKPIPLAIAAVLCALVLALPVPDGVKPQAWTLLAMFIGV
                     IAAIIGKAMPLGALSIIAVGLVAVTGVTADKPGAAMSDALSAFANPLIWLIAIAVMIS
                     RGLLKTGLGMRIGYLFIAVFGRKTLGIGYSLALSELLLAPVTPSNTARGGGIIHPIMQ
                     SIAGSYGSNPAKGTEGKMGKYLALVNYHSNPISSAMFITATAPNPLIVNLIAENLGSS
                     FRLSWGAWAWAMAVPGVIAFFVMPLILYFLYPPEIKETPNAVQFAKDRLREMGKMSAD
                     EIIMAVIFGILLLLWADVPALITGNHAFSINATATAFIGLSLLLLSGVLTWDDVLKEK
                     SAWDTIIWFGALIMMAAFLNKLGLIKWFSGVLAESVGGLGVSGTAAGVILVLAYMYAH
                     YMFASTTAHITAMFGAFFAAAVSLNAPAMPTALMMAAASNIMMTLTHYATGTSPVIFG
                     SGYTTMGEWWKAGFIMSVVNFLIFFVIGSIWWKVLGYW"
     gene            complement(11858..12934)
                     /locus_tag="ACFOV4_001043"
     CDS             complement(11858..12934)
                     /locus_tag="ACFOV4_001043"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HFC7619069.1"
                     /translation="MICRKPIGHTPYFDMNKTICRTAALLISGFSYANTVIPDVSPVA
                     QGQHVFINIPQQRLFLYTDGKLTKVYPVAVGRAMTQTNLGEHKIGAKAYNPVWYIPKS
                     IQKERGDGVKTIAAGPDNPLGPVFVRLGDPKLGLGIHGTNAPASVPGVRSHGCVRMKS
                     PDALEFAKTIASGSPASVIYQMAGLNEDADRNLWLAAFRDPYGKNNLDIASLKKSIAQ
                     WAKTQGKTIAPEKVDAVLKDRTGSAVCLTCGKNGKMKMPLKSLAWIQGSSSYSQAEVI
                     EQTEETNSAEISETRTPEVPDVHTPEAQPHLNTQSDGTPTAYTEPAADSSPQVETPDQ
                     AASEPVDVLFSIDVIRQGNLRLGN"
     gene            12998..13135
                     /locus_tag="ACFOV4_001044"
     CDS             12998..13135
                     /locus_tag="ACFOV4_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase"
                     /protein_id="HFC7619070.1"
                     /translation="MATETNVAEISALDYEGRGVAKVGGKTVFIKRALLDCLMLGWFR
                     L"
     gene            13157..14299
                     /gene="bioF"
                     /locus_tag="ACFOV4_001045"
     CDS             13157..14299
                     /gene="bioF"
                     /locus_tag="ACFOV4_001045"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008710 - 8-amino-7-oxononanoate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HFC7619071.1"
                     /translation="MKVFKQQLEQLGAQNQYRSIPDLIHQGRYITRENRKMLNMSSND
                     YLGLASDENLRRSFLQQYGGNFPSFTSSSSRLLTGNFPIYTDLEELVAQRFQRESALL
                     FNSGYHANLGILPALTTTKSLILADKFVHASMIDGIRLSRCAFFRYRHNDYEHLKNLL
                     EKNVGKFDRTFIVTESVFSMDGDVADLKQLVQLKKQFPNTYLYVDEAHAIGVYGQNGL
                     GIAERDNLIAEIDLLVGTFGKALASVGAYAVCNQVLKECLINQMRPLIFSTALPPFNV
                     AWTYFIFERLPQFSKERSHLEQLSAFLRREVAHRTQIMPSQTCIVPYILGGNEATLAK
                     AEYLQRQGYYCLPIRPPTVPKGTSRIRLSLTADMTMDEVRQFAACL"
     gene            14309..14956
                     /locus_tag="ACFOV4_001046"
     CDS             14309..14956
                     /locus_tag="ACFOV4_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl esterase BioG family
                     protein"
                     /protein_id="HFC7619072.1"
                     /translation="MKTKFYDCQGGHLILYFAGWGTPPDAVNHLILPENHDLLICYDY
                     QDLNLDFDFSAYRHIRLVAWSMGVWAAERALQGIRLKSATAVNGTGLPCDDNFGIPYA
                     VFKGTLENLTENTRLKFERRICGDKASFERYQQFSARPFDEIHQELTALFAMIGQDRR
                     TDLIRWTNALVGSGDKIFMSANQHRYWTARCTVREIDGGHYLFSRFTHWSALWNH"
     gene            14944..15726
                     /gene="bioC"
                     /locus_tag="ACFOV4_001047"
     CDS             14944..15726
                     /gene="bioC"
                     /locus_tag="ACFOV4_001047"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010340 - carboxyl-O-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HFC7619073.1"
                     /translation="MESLTAINKSRIRQAFQKALNDYDRHALIQQKMTINLMAHLQDY
                     LPDMPLENVLELGCGSGMLSALLQKQISANYWLFNDLCDVQPQLAEKLPQSFDFYCGD
                     AENFPFQRQFDLIASASAVQWFHQPDAFIAHCKTGLKANGLLAVATFGKDNLKEVRQI
                     TNIGLNYPTLSQWQTWLAKDFELLWCEDFKVILDFDTPLDVLKHLKYTGVTATNQKNW
                     TRKNLNGFIGDYLSAFSMPSGKVRLTYHPLFFIARYSEAGRQ"
     gene            15946..17382
                     /locus_tag="ACFOV4_001048"
     CDS             15946..17382
                     /locus_tag="ACFOV4_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFC7619074.1"
                     /translation="MENSLIIGLALAVLLMLLVMRAKQGKKTPKRKSQGVGNTQGQTP
                     GSNDSDWVDQIGQSVSDGTQPDWSWNESAETASAAVSAQEVDPLTEYQVYKQFGYQGK
                     AAESLAAYLDGIPDGEAKPENLIRELLDINLEVGDVDVLADNLQKYGKLIPSELLAKY
                     IEQALQRDSNHLRIRVLAEEGLGWGTQEIEKRAEGGSATAASASPPPDAGGKAYEAEE
                     IKRIPIVRGKKDVSGISQEEIGAIAGLVRADQGAKILKDKVSYETASKQYDRAIQTSE
                     KPANLIIDALKLDYQYADIDRFAGHLWKLYQTLGNYGRQVKERMLGWGYSLGYHEVFD
                     DLEKGPNDRQIKDIGMGHGYLPKNIQKFKSQHRDLVLQDSSLINTGSSPADDAVKEVE
                     SLLMYGQIEAAMDVLEQAVLKYPDESQLYITLIDIYERTEDWDRLGQFLRVLRERADR
                     LPEEVVMLMSRLLQRMNQNIKKIKRYGK"
     gene            17385..18482
                     /locus_tag="ACFOV4_001049"
     CDS             17385..18482
                     /locus_tag="ACFOV4_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFC7619075.1"
                     /translation="MEVQLPKIKTVRVMLAGMTAQQESVFKMAFKMHNTTRYETVSPS
                     DGSAVPDLVLADTDAEGGFELWKELAERYKDIPVAVCSEKVPDSEVPYLPKPIRFETL
                     FPMLRKLLQGENVYGKSFIAPADRSAKNNGNVQRTVTIRQFNPNKGLLGALRFAEKNR
                     QDIAILHGNKPVLIVFPSIQRVLLTESVQKLEELCKDENLQVSCKTVPDNPQWREKAK
                     VGIMSCMWQFSIWTAQGRLIYPISPDTPFTLKSWPNLTRLANVPGSIRLSAFLTKASV
                     NLNVLYKVMPLNLNDILNYLAATYTTGFLSVDLKTVSQQAYSDMADKINIGADSASDS
                     EMMKKAEKITTSSQSQSRGLLQRLMKKLLGS"
     gene            18494..19030
                     /locus_tag="ACFOV4_001050"
     CDS             18494..19030
                     /locus_tag="ACFOV4_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
                     /protein_id="HFC7619076.1"
                     /translation="MRENKIIFTGPVGVGKTTAIAAISDEALVQTDASASDMTLDRKR
                     NTTVAMDYGAISLDEDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLLDNARTNPLKD
                     LEFFLHSFRGLLEKAPVVVGITKMDIRSQPGIDVYHKYLAKHNLNVPVFEIDARKEDD
                     VKQLVSAMLFSIDPGLEV"
     gene            19032..19676
                     /locus_tag="ACFOV4_001051"
     CDS             19032..19676
                     /locus_tag="ACFOV4_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFC7619077.1"
                     /translation="MESTLSLQANLYPRLTPAGAFYAVSSDAPSAGKTLLHSLLKADA
                     DEMVSSEKLLTWADTADIDTALNLLYRLQKLEFLYGDENGHSDGINLSDEQLPLLMEQ
                     LSGSGKALLVDRNGLYLANANFHHEAAEELGLLAAEVAQMEKKYRLLIKNNLYINNNA
                     WGVCDPSGQSELTFFPLYIGSTKFILVIGGIPDLGKEAFVTLVRILYRRYSNRV"
     gene            19699..20058
                     /locus_tag="ACFOV4_001052"
     CDS             19699..20058
                     /locus_tag="ACFOV4_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="HFC7619078.1"
                     /translation="MQQLLISILEDLNNTSTDIIASAVISTDGLPMATMLPSHLNSDR
                     VGAISATLLALGSRSVQELACGELEQVMIKGKSGYILLSQAGKDAVLVLVAKETGRLG
                     LILLDAKRAARHIAEAI"
     gene            20151..20226
                     /locus_tag="ACFOV4_001053"
     tRNA            20151..20226
                     /locus_tag="ACFOV4_001053"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20184..20186,aa:Asn,seq:gtt)
     gene            complement(20726..21121)
                     /locus_tag="ACFOV4_001054"
     CDS             complement(20726..21121)
                     /locus_tag="ACFOV4_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IgG-binding virulence factor TspB family
                     protein"
                     /protein_id="HFC7619079.1"
                     /translation="MMYSFEANANAVKISETVSVDTGQGAKIHKFVPKNSKTYSSDLI
                     KTVDLTHIPTGAKARINAKITASISRAGVLAGGGKLARLGAKFSTRAVPYVGTALLAH
                     DVYETFKEDIQARGYQYDPETDKFAKVSG"
     gene            complement(21105..21422)
                     /locus_tag="ACFOV4_001055"
     CDS             complement(21105..21422)
                     /locus_tag="ACFOV4_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1132 family protein"
                     /protein_id="HFC7619080.1"
                     /translation="MNKPFITQAQLALYKYQPSSKYFGQSMAVIAQSEFVEFAKINKS
                     ENVIDCFSFFWNRRIKHDIWLISFSDNSEKVIKESLKDGHKIYKFEFCEIVDNCNFDD
                     VFV"
     gene            complement(21550..21828)
                     /locus_tag="ACFOV4_001056"
     CDS             complement(21550..21828)
                     /locus_tag="ACFOV4_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619081.1"
                     /translation="MYYQVGNKCLEKHQAENLYFSLVVPRIKENGQIVRPEYNGSLWK
                     MSDGQPLRLLLAECSPKDNLQSGLETGWIVFGILASVYFVSLLKKVLK"
     gene            complement(21835..22053)
                     /locus_tag="ACFOV4_001057"
     CDS             complement(21835..22053)
                     /locus_tag="ACFOV4_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFC7619082.1"
                     /translation="MKFINTCRKYGAKLAVVTAAPLALAAHANATLPDTAKNALEAAK
                     ADGMEAGWIVVGVFAALFVFSIVKRVMK"
     gene            complement(22127..22324)
                     /locus_tag="ACFOV4_001058"
     CDS             complement(22127..22324)
                     /locus_tag="ACFOV4_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619083.1"
                     /translation="MQKVYVVQSVSTGDFLYLSPETGDIGHTKLITNADYFYDFEEAI
                     NAGLEEIGNQYEFVVFGFLKD"
     gene            complement(22329..22619)
                     /locus_tag="ACFOV4_001059"
     CDS             complement(22329..22619)
                     /locus_tag="ACFOV4_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619084.1"
                     /translation="MNIQLQGHIVGVKKFNGQIEGKSFDYCRLIVATPLDSSQGNALG
                     SSTTEYDFGGSANFEQFRNAQFPIEANLNVEIVTTGKTQKLKVIGFQPVKKG"
     gene            complement(22664..24007)
                     /locus_tag="ACFOV4_001060"
     CDS             complement(22664..24007)
                     /locus_tag="ACFOV4_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFC7619085.1"
                     /translation="MEDKQGMTKAVVGVMTDALADGRKPATASNLPPLSNRGGTETET
                     AGRVQEVFECYETYITDGKGNLLGVPLRRGVSDSAFIDQISFSFHEKTFFDKYGVRVS
                     LLEDEDFIRAASMLAEEVFGFGIYKESKGSGGRFYERCWLMGSEDVLYGRVHFGGQNN
                     TILFELTGTGCGVAKEGWESRLFAFLTNAIRPKITRVDIAKDFFNGEYSPNQAREDRN
                     KGMFTCHHVKPKGECLGSDWEEDDEAKMTKGKTYGIGSRESSKYVRVYEKGKQLGDKT
                     STWTRFEIEFKAKDIVIPFEVLQNPGEYFGGAYPICERFVQKATRIHAVKEDKVISAD
                     RYLEWVKKQFGRAANGLKFIFPELDKAKLFELIEPSHHKLPKSLAPEAYDCAFLKAQA
                     IHEQPAFKPYKDPYYMYEYYENLEKQLEQQKHVNNEESYNNFIYDKFARLPISWA"
BASE COUNT         6093 a         5570 c         6053 g         6364 t
ORIGIN      
        1 aaacttaaaa caagcgaaac cgaacgaact ggattcccac tttcgcggga atgacggcgg
       61 agcggtttct gctttttcca ataaatgacc ccaacttaaa atcccgtcat tcccgcgcag
      121 gcgggaatct agacattcaa tgctaaggca atttatcgga aatgactgaa actcaaaaaa
      181 ctggattccc actttcgtgg gaatgacggg atgcaggttc gtgggaatga cgggatttga
      241 ggtttctgtt tttgattttc tgttttcgtg ggaatgacgg tttagaagtt acccgaaacc
      301 tcaaaaaaac cgaaaccgaa cggatcggat taccgctttc gcgtttcaaa gttacggcgt
      361 tatcggaaaa acagaaaatc aaagctgcaa gaatttattt aaaacaaccg aatttcaacg
      421 gatcggattc tcgcctgtag ggaatgacgg cggaaggttt tttgtctttt ctgacagatg
      481 tccgcaatct gaaatcctga ccgtgggaac gacggtatag tggattaaca aaaaccagta
      541 cggcgttggc tcgccttagc tcaaagagaa cgattctcta aggtgctgaa gcaccaagtg
      601 aatcggtttc gtactatttg tactgtctgc ggctttgtcg ccttgtcctg atttttgtta
      661 atccactata taaatatttc tatttcaatc caatataaaa tgccgtccga acgatgttcg
      721 gacggcattt ttaatgcttc aaatcagttg gtgccgactt tgattttctg ccacaggctg
      781 acagacagtt ttttcgcatc cgtactcatt tgcggcatca caaaaccgtc tttcatatcc
      841 tgctcgttcg ggaagatgga acgggtgttt accagttcgg caggcatttt ttcgcgcgcc
      901 ggtttgctgg cgggggcgaa ggttacggcg atgccgtttt tcgccgcgat ttcggggtcg
      961 agcgtgtagt tgatgtattt gtgggcattg gcgacgtttt tcgcatcggc cggaatcagc
     1021 caagattcaa tccagaagcc catgcctttc ggattcaaca cttcgatgcc gacgttgttt
     1081 ttcacttctt cggaacgtgc tttcgccaag ttcaaatcgc cgccgttgcc tgccgccagg
     1141 cagatgtcgc cgcgcgccag ctcgtcgatg atggacgggc tgaaacgttt gacatccgga
     1201 cggatagact tcaacacttc cgccgccgcc ttcaaatctt caggattcga gcctttgggg
     1261 tctttgccca agtagttcag caaaatcggg aacatttcgc tcggggtgtc ccacagggcg
     1321 atgccgcagg atttcagctt gtgggtgtat tcgggtttga acagcaaatc ccagccgttt
     1381 tcgggcagct tgccgcccaa aagctctttg cctttcgccg taatcgcaat cgtgttcacg
     1441 ccggagaaat aggggacggc atactggttg cccgggtcgg cggtttccag cattttcaag
     1501 agttcgggat cgatgttttt atagttggga atcaggtctt tgttgacttt ttgatacgcg
     1561 cccgcctcga tttggcgcgg taggaaggcg atgcccggca caaccaaatc gtaaccggat
     1621 ttgccggtca gcattttggc ttccagcgtt tcattgtttt cgtacaagtc gtaagtcagc
     1681 ttcagattat tggctttttt aaagtcttcg accgtactct cgtcaacata gttcgaccag
     1741 ttgtagatgt tcagagtatc ggtggcagcg gcttcggcat tggcagcaga cgcagcgtct
     1801 gcttgaggtt gcacggcgtt tttttcgctg ccgccgcagg ctgccaaaga cagcgcggcc
     1861 aaaacggcta atacggattt tttcatacgg gcagattcct gatgaaagag gttggaaaaa
     1921 aaagaaaacc ccgcgcccca taaacacccc ggcgcaaggt ttgggcattg taaagtaaat
     1981 ttgtgcaaac tcaaagcgat attgacctga ttttcctaaa aaattacctt gttttcaaaa
     2041 gagggagaaa acgtccgcac gattttgccg tttttttgcg ctgtcagggt gtccgacggg
     2101 cggatagaga gaaaaggctt gcatataatg taaaccccct ttaaaattgc gcgtttacag
     2161 aatttatttt tctttcagga gattccaata tggcaaacag cgcacaagca cgcaaacgtg
     2221 cccgccagtc cgtcaaacaa cgcgcccaca acgctagcct gcgtaccgca ttccgcactg
     2281 cagtgaaaaa agtattgaaa gcagtcgaag caggcgataa agctgccgca caagcggttt
     2341 accaagagtc cgtcaaagtc atcgaccgca tcgccgacaa gggcgtgttc cacaaaaaca
     2401 aagcggcacg ccacaaaagc cgtctgtctg caaaagtaaa agcactggct tgatttttgc
     2461 aaaaccgcca aggcggttga tacgcgataa gcggaaaacc ctgaagcccg acggtttcgg
     2521 ggttttctgt attgcggggg caaaatcccg aaatggcgga aagggtgcgg tttttatccg
     2581 aatccgctat aaaatgccgt ttgaaaacca atatgccgac aatgggggcg gagatgaata
     2641 cacggaatat gcgctatatt cttttgacag gactgttgcc gacggtatcc gcttttggag
     2701 agaccgcgct gcaatgcgcc gctttgacgg acaatgttac gcgtttggcg tgttacgaca
     2761 ggatttttgc ggcacagctt ccgtcttcgg cagggcagga agggcaggag tcgaaagccg
     2821 tactcaatct gacggaaacc gtccgcagca gcctggataa gggcgaggcg gtcattgttg
     2881 ttgaaaaagg cggggatgcg cttcctgccg acagtgcggg cgaaaccgcc gacatctata
     2941 cgcctttgag cctgatgtac gacttggaca aaaacgattt gcgcgggctg ttgggcgtac
     3001 gcgaacacaa tccgatgtac cttatgccgc tctggtacaa caattcgccc aactatgccc
     3061 cgggttcgcc gacgcgcggt acgactgtac aggaaaaatt cggacagcag aaacgtgcgg
     3121 aaaccaaatt gcaggtttcg ttcaaaagca aaattgccga agatttgttt aaaacccgcg
     3181 cggatctgtg gttcggctac acccaaagat ccgattggca gatttacaac caaggcagga
     3241 aatccgcgcc gttccgcaat acggattaca aacctgaaat tttcctgacc cagcctgtga
     3301 aggcggattt gccgttcggc ggcaggctgc gtatgctcgg tgcgggtttt gtccaccagt
     3361 ccaacggaca gagccgtccc gaatcgcgtt cgtggaacag gatttacgcc atggcaggca
     3421 tggaatgggg caaattgacg gtgattccgc gcgtgtgggt gcgtgcgttc gatcagagcg
     3481 gcgataaaaa cgacaatccc gatattgccg actatatggg gtatggcgac gtgaagctgc
     3541 agtaccgcct gaacgacagg cagaatgtgt attccgtatt gcgctacaac cccaaaacgg
     3601 gctacggcgc gattgaagcc gcctacacgt ttccgattaa gggcaaactc aaaggcgtgg
     3661 tacgcggatt ccacggttac ggcgagagcc tgatcgacta caaccacaag cagaacggta
     3721 tcggtatcgg gttgatgttc aacgacttgg acggcatctg aaccgcgtgt tcagacggta
     3781 tatcaagttg ccgtgccgtc tgaagccgct ggcggtttgg cggggcggga taaaaatttc
     3841 gtttgaatcc gggcaaacgc gtataatgtg cggtttgtac ggactttgtc ggaatcaagc
     3901 aagatgacgg aacctgaggc cgaaggcggt aaagctgcca aggcgttaaa aaaatatctg
     3961 attacgggca ttttggtctg gctgccgatt gcggtaacgg tttgggtggt ttcctatatc
     4021 gtttccgcgt ccgatcagct cgtcaacctg ctgccgaagc aatggcggcc gcaatatgtt
     4081 ttgggcttca atatcccggg gctgggcgtt atcgttgcca ttgctgtatt gtttgtaacc
     4141 ggattgtttg ccgcaaacgt attgggccgg cagattcttg ccgcgtggga cagcctgttg
     4201 gggcggattc cagttgtgaa gtccatctat tcgagtgtga aaaaagtatc cgaatcgctg
     4261 ctgtccgaca gcagccgttc gtttaaaaca ccagtactcg tgccgtttcc ccaatcgggt
     4321 atttggacaa tcgcattcgt gtccggtcag gtgtcgaatg cggttaaggc cgcattgccg
     4381 aaggacggcg attatctttc cgtgtatgtt ccgaccacgc cgaatccgac cggcggttac
     4441 tatattatgg taaagaaaag cgatgtgcgc gaactcgata tgagcgtgga cgaagcattg
     4501 aaatatgtga tttcgctggg tatggtcatc cctgacgacc tgcccgtcaa aacattggca
     4561 ggacctatgc cgtctgaaaa ggcggatttg cccgaacaac aataaagccg ccgttcagac
     4621 ggcattttct gttttcagtt taaatcaata aaaggtgaat ttatgcgtac caactattgc
     4681 ggcctgatca gcgagcaata cttagaccaa accgtaaccg tcaaaggctg ggtacaccgc
     4741 cgacgcgacc acggcggtgt gatttttatc gacctgcgcg accgcgaagg catcgtccaa
     4801 gtcgtgattg accccgacac tccggaagcg tttgctgctg ccgattccgc ccgcaacgaa
     4861 tacgttttga gcattaccgg ccgcgtacgc aaccgtcccg aaggtacaac caacgacaaa
     4921 atgatttccg gcaaaatcga aattcttgcc aaagaaatcg aagtattaaa cgccgccgct
     4981 acgcctccgt tccaaatcga cgatgaaaac atcagcgaaa acgttcgcct gaccaaccgc
     5041 gttatcgacc tgcgccgtcc ggtgatgcag cgcaacctgc gcctgcgtta ccaagtggct
     5101 atgggcgttc gccgctactt ggacgcgcaa ggtttcatcg acattgaaac cccgatgctg
     5161 acccgctcca cgcctgaagg cgcgcgcgac tacctcgtgc cgagccgcgt tcatccgggc
     5221 gagtttttcg cgctaccgca atcgccgcaa ttattcaaac aactgttgat ggtggcgggt
     5281 ttcgaccgtt actaccaaat caccaagtgc ttccgcgacg aagacctgcg tgccgaccgt
     5341 cagcctgaat ttacccaaat cgacttggaa acctcgttct taaacgagga tgaaatcatg
     5401 gacatcaccg aaggtatggc gaaacaagtc ttcaaagacg cgctgggcgt ggacttgggc
     5461 gacttcccac gcatgcctta ctctgaagcc atgttctact acggctctga caaaccggac
     5521 atgcgtatca acttgaaatt caccgagttg accgacctga tgaaaacgga agaattcaaa
     5581 gtcttccgtg gcgcggcaga tatgaaaggc ggccgcgtag tcgctctgcg tgtaccgaac
     5641 ggcgcgaaat tcagccgcaa agaaatcgac gaatacacca aatttgtcgg catctacggt
     5701 gcgaaaggtc tggcatacat caaagtaaat gatgtgggca acctctccaa cggcgaagac
     5761 agcggcctgc aatctccaat cgtaaaattc ctgtctgaga atgccctgaa ggaaatcatc
     5821 gcgcgtaccg gcgcacaaaa cggcgatatt atcttcttcg gtgcagacaa aaccaaagtc
     5881 gtaaacgaag ccatcggcgc attgcgtatc aaagtcggct tggaacacgg cgcggaaaac
     5941 ggctatttca cagacgaatg gaaacctttg tgggttgtcg acttcccaat gttcgaatac
     6001 gacgaagaag ccgaccgcta cgttgccgta caccatccgt ttactgcgcc aaaagaaggt
     6061 catgaagacc tgatggtttc cgacccggca aattgtttgg cacgcgccta cgatatggta
     6121 ttgaacggct gggaaatcgg cggcggctct atccgtatcc accgcgcaga cgtgcaagag
     6181 aaagtgtttg ccgcgctgaa aatcagccct gaagagcaac aagagaaatt cggcttcctc
     6241 ttggacaacc tgaaattcgg tgcgcctcct cacggcggcc ttgcattcgg cctcgaccgt
     6301 ctggtaacgc tgatgaccgg agccgaatcc atccgcgacg tgattgcctt cccgaaaaca
     6361 caacgtgctc aatgcctgct gaccaacgcg cccaacagcg tggacgacaa gcagttgcgc
     6421 gaattgagct tgcgcctgcg tcaaaaggcg gctgaaacca aagaagcata aggaaaacag
     6481 agccgtttga cggctctgtt tttttcagac ggcatttacg cttcttgact tccctctaat
     6541 tcaaacctaa ttttgctgtg ttttaatggc ggtattgaaa aacacatctt gttcaatcaa
     6601 ccgataaaaa aaggactgaa aatgaaaaaa ctgttattgg ccgccgttgt ttccctgagt
     6661 gccgcaaccg catttgccgg cgattctgcc gagcgtcaga tttacggcga tccccatttt
     6721 gaacaaaacc gcacaaaagc cgtgaaaatg ttggaacagc gtggttatca ggttcacgat
     6781 gtcgatgccg acgaccattg gggtaagcct gtgctggaag tggaagccta taaagacggc
     6841 cgcgaatacg acatcgtgtt gtcttacccc gacctgaaaa tcatcaaaga gcagctcgat
     6901 cgctgactcc tttgatggca agctgaacca aaatgccgtc tgaagcgttc agacggcatt
     6961 ttgcctgttc ctcatcaggt atgaggcagg cttttcttat taaaaaaatg acatttcacg
     7021 ctgatttgtt ataatcattc cttttcaaca cgacagacgg agcaggttta ttatgcctat
     7081 ccttaccatc cgtgaagtgt gcaacattaa tcattggggt ataggttatt atgatgttga
     7141 cgattccggc gaaatcatcg tccgccccaa tccctcgcaa cacaatcaaa ctgtttcact
     7201 gcaaaaactg actgaagccg tgcaacaaaa acatcaggcg cgcctgcctg ttttgttttg
     7261 ttttccgcaa atcctcgaac accgcctccg cgacatcaac cgcgcctttc agacggcacg
     7321 ggaagagtgc ggctataagg gcggttattg tttggtttac cctatcaagg tcaaccaaca
     7381 ccgccgcgtc atcgaatcgc ttatgtcaag cggacaaccg catggtttgg aagctggttc
     7441 taaagccgaa ctgatggcgg ttttggcaca cgccggcacc cggcaaacat taatcgtctg
     7501 caacggctat aaagaccgtg aatatatccg tttcgccttg atgggcgaaa aactggggca
     7561 tcaggtttat ttggtgattg agaagctgtc cgaaatacaa atggtattgg aagaggcgga
     7621 aaaactcggc atcaagcccc gtttgggtgt gcgcgccaga ctggcttccc aaggttcggg
     7681 aaaatggcag tcttcgggtg gggaaaaatc aaaattcggc ttgtcggctt cccaagtttt
     7741 gcaactggtc gatattttga aacaaaaaaa caggctggat tgcctgcagc ttttgcattt
     7801 ccatttgggc tcgcagcttg ggaacatccg tgatgttgcc acaggtgtac acgaatcggc
     7861 tcggttttat gttgagttgc acaaactggg ggtaaatatc cgctgttttg atgtaggcgg
     7921 cgggcttggc gtggattacg aaggaaaccg cacacaatcg gattgttccg ttaattacag
     7981 cctcaacgaa tatgccgcca cagtcgtatg gggcatcagc caggcttgtc tcgaacacgg
     8041 gctgccgcat ccgacaatca ttaccgagag cgggcgcggc attaccgcac atcacgccgt
     8101 tttggttgct aatgttatag gcgttgaacg ttacaaaccg cgccggctgg atgcgccatc
     8161 gcccgaagca ccgcgtgtgt tgcacagtat gtgggaaact tggacggata tttccgcctc
     8221 gcgggaaaaa cgttccttac gcagctggat acacgaaggg cagtttgatc ttgccgatgt
     8281 gcataatcag tataatgtcg ggctgttgag tttggcgcaa cgtgcgtggg cggagcaact
     8341 gtatttaaat atctgtcatg aagtcggcga attgtttaat gaaaaacacc ggtctcaccg
     8401 aaccattatt gacgaattgc aagaacgttt tgccgataag ctgtatgtca atttctcact
     8461 cttccaatct ttgcccgatg cttggggcat agatcaactt ttccctgttt gtcccattac
     8521 cggtttgaat gaaccgattg cgcgccgcgc cgtgttgttg gacattacct gcgattcaga
     8581 cggtacgatt gaccactaca tcgacggcga cggcatcgcc ggtacgatgc ctatgcctga
     8641 ttatcccgaa gaagagccgc cgcttttagg cttttttatg gtgggagcat atcaggaaat
     8701 actcggcaat atgcacaatc ttttcggcga cactgccact gccgatgttg ttgtagggga
     8761 agacggacaa tttaccgtca tcgattacga tgaaggaaac accgttgccg atatgctcga
     8821 atacgtttat caagatccga aagagctgat gaaacgctat cgcgaacaaa tcgaacattc
     8881 agaccttcct gcctcgcagg ctatgtcttt cttaaaagaa ctcgaagcgg ggcttaatgg
     8941 ttatacctat ttggaagacg aatagacgca tcaaggcatc ggatatgtcg tctgaagccc
     9001 gattttctta ctcaaacacc aatcatcacg accgattgaa accaattaca aggaatcatt
     9061 acgatgcaat acagcacact ggcaggacaa accgacaact ccctcgtttc caataatttc
     9121 gggtttttgc gcctgccgct taattttatg ccgtatgaaa gtcatgccga ttgggttatt
     9181 accggcgtgc cttatgatat ggcggtttca gggcgttccg gcgcgcgttt cggtcctgaa
     9241 gccatccggc gcgcctccgt caacctcgct tgggagcacc gcaggtttcc atggacattt
     9301 gatgtgcgcg aacgcctgaa cattattgat tgcggcgact tggttttttc ttttggcgac
     9361 agcagggatt ttgtcgaaaa aatggaagcg cacgccggca aattactttc ttccggcaaa
     9421 cgctgtttga gtttgggcgg cgaccatttc attaccctac cgttgttgcg cgcccacgcc
     9481 cgctatttcg gcaaactcgc actgattcat tttgacgcgc acaccgacac ctacgacaac
     9541 ggcagcgaat acgaccacgg tacgatgttt tataccgccc ccaaggaagg catcatcgat
     9601 ccggcacatt ccgtgcaaat cggcatacgt accgaacaca gtaaaaaatt gccttttact
     9661 gtgttgaccg ccccccaagt caatgaagac agtgttgaag agaccgtccg taaaatcaaa
     9721 gaaaccgtcg gcaatatgcc cgtttacctg actttcgaca tcgactgcct ggacccgtcg
     9781 ttcgcccctg ggaccggtac gcccgtatgc ggcggcttga gcagcgacag ggcattaaaa
     9841 atcctacgtg ggctgacgga tctcgacatc gtcggtatgg atgttgtaga agttgccccc
     9901 tcttacgacc aatccgacat taccgctttg gccggtgcca caattgcctt ggaaatgctt
     9961 taccttcaag gtgcgaaaaa ggactgaacg tccggcatcc cccgggtttt cgccgtgccg
    10021 ttcaaacggc gtattcagtc taatgaaaat tcaaatactg aaacaaaagt tgcccggagc
    10081 cgcatatcgg aaagacggtg aaatatcgga atatatctta taaaacaatt agttaaatat
    10141 tatttttccg atttttcggg acggtctttt ttacggaggt caatatgatg aaattgggtt
    10201 tcaaaccgat acccctcgcc attgccgcag tattgtgcgc cttggttttg gcactgcccg
    10261 tacccgacgg ggtcaagcct caggcttgga cgctgctggc catgtttatc ggtgtgattg
    10321 ccgccattat cggcaaggcc atgccgttgg gtgcgctgtc gattattgcc gtcgggttgg
    10381 tcgcagtaac cggcgtaacc gccgacaaac cgggtgcggc gatgagcgat gcgttgagtg
    10441 cgttcgccaa tccgttgatt tggctgattg ccatcgcagt tatgatttcg cgcggtttgc
    10501 tcaaaacagg gctggggatg cgtatcggat atttgtttat cgccgttttt ggaagaaaaa
    10561 cgctgggcat cggttacagt ctcgctcttt ccgaactgct gctggctccc gttacccctt
    10621 ccaataccgc gcgcggcggc ggcattatac atccgattat gcagtcgatt gccggcagtt
    10681 acggctccaa tcccgcaaaa ggcacagaag gcaagatggg taaatatttg gctttggtca
    10741 actatcattc caatcccatt tcgtcggcta tgtttattac tgcaactgcc cccaaccctt
    10801 taatcgtcaa cttgattgcc gaaaatttag gcagtagttt ccgtctttct tggggggcgt
    10861 gggcgtgggc aatggctgtt cccggcgtta tcgccttttt cgttatgcct ttgattttat
    10921 attttttgta tccgcctgaa attaaagaaa cgcccaatgc cgttcaattt gccaaagacc
    10981 gtctgaggga gatgggtaaa atgtcggcag acgaaatcat tatggcggtc attttcggta
    11041 tcttgttgct gttgtgggca gatgttcccg cccttattac cggcaatcac gcttttagta
    11101 tcaacgccac cgccaccgca tttatcggat taagcctgct tttgctttcc ggtgtattga
    11161 cttgggacga tgttttgaaa gaaaaaagcg cgtgggatac gattatttgg tttggcgcat
    11221 tgattatgat ggccgcattt ttaaataaac tcggactgat taaatggttc tccggagtgt
    11281 tggcggaaag tgtcggcggt ttgggcgtta gcggcacggc tgcgggcgta atcctcgtgc
    11341 ttgcttatat gtatgcgcat tatatgtttg ccagtactac tgcacatatt accgctatgt
    11401 tcggcgcatt tttcgctgct gccgtttcac tgaatgcccc ggcgatgccg accgcgctga
    11461 tgatggcggc cgcatccaac attatgatga ccctcactca ttatgcgacc ggtacttcgc
    11521 ctgtgatttt cggttcgggc tacaccacaa tgggagaatg gtggaaggcg ggttttatca
    11581 tgagcgtggt caattttctg atttttttcg ttatcggcag catttggtgg aaagttctgg
    11641 ggtattggta agggaaaaat aaaataaatt tccaatctgt gtttatttga ttgggcgact
    11701 attatcgtga aatatgccgt ctaaagcctt cagatggcat atttgtgcgc ttgaatgttg
    11761 cagaaagcgg caggcggcgg tgtaggaaaa gccaaacaaa aaccaaaccg cctatcaact
    11821 tctgataaac ataagcatta aataatcaga aggttattca attacctaaa cgcaaatttc
    11881 cctgccgtat cacatctatt gaaaataata catcaaccgg ctcggaagca gcctgatcag
    11941 gtgtttctac ttgcggcgat gaatcggcag ccggttcggt ataggcagtc ggcgtgccgt
    12001 cggattgggt atttaaatgc ggttgtgcct cgggcgtgtg tacatcaggc acttcgggcg
    12061 tgcgtgtctc ggatatttcg gcagagttgg tttcctcagt ttgttcaatg acttcagctt
    12121 ggctgtatga ggaagaaccc tgtatccacg ccagcgattt gagcggcatc ttcatcttgc
    12181 cgtttttgcc gcaggtcagg cagacggccg atccggtgcg gtctttgagt acagcatcga
    12241 ctttctcggg cgcgatggtt ttaccctgtg tttttgccca ttgcgcaata ctttttttca
    12301 gagaggcgat gtcaaggttg ttcttaccgt aagggtcgcg gaaggcggca agccacaggt
    12361 tgcgatccgc atcttcattg agccccgcca tttgatagat gacggaggcg ggcgagccgc
    12421 tggcgatggt tttggcaaac tcgagcgcgt cgggcgattt catgcggacg cagccgtgac
    12481 tccgaacccc ggggacgctg gccggcgcat tggtcccgtg tatgcccaaa ccgagtttgg
    12541 ggtcgcctaa gcggacaaaa accggcccca aagggttgtc cgggccggcg gctatggttt
    12601 ttacgccgtc gccgcgttct ttctgtatgg atttggggat gtaccaaaca gggttatagg
    12661 ctttcgcacc gattttatgt tcgcctagat tggtttgcgt catcgcccga cctactgcaa
    12721 cgggataaac cttggtcagt ttgccgtcgg tgtagaggaa caggcgttgc tgagggatgt
    12781 taatgaagac atgttgacct tgtgcgacgg gggagacatc gggaatgacg gtgtttgcgt
    12841 atgaaaaacc gcttatcaat agtgcggcag tgcggcagat tgttttattc atatcaaaat
    12901 atggtgtgtg tccgataggt tttcggcaaa tcatacctga aaccgtacca atttgtgcga
    12961 aaatatgcgc ttcggtacag tgcggacgga ttgggtaatg gcaacggaaa caaatgtcgc
    13021 ggaaatttcc gccttggatt atgaaggcag gggtgtggca aaggtcggcg gcaaaacggt
    13081 ttttattaaa agggcattac ttgattgttt gatgctgggt tggttcaggc tttaactcag
    13141 gaatatttac atcataatga aggtttttaa acaacagctt gaacaactcg gcgcgcaaaa
    13201 ccaatatcgt tcgattccgg atttgattca tcaagggcgg tatattacgc gggaaaaccg
    13261 caaaatgctg aatatgtcgt ctaatgatta tttgggtttg gcatcagatg aaaacttgcg
    13321 ccggtctttt ttgcagcaat acggcggtaa ttttccctct tttaccagtt cttcatcgcg
    13381 tttattaacg ggcaactttc ctatttatac cgatttggaa gagcttgtcg cacaacgttt
    13441 ccaacgggaa agcgcgttat tgttcaacag cggctatcac gccaatctcg gtattttgcc
    13501 tgctttgacg acgacgaaaa gtttgatttt ggcagataaa tttgttcacg ccagtatgat
    13561 tgacggcatc cgtttgagcc ggtgtgcgtt tttccgttat cgtcataatg attatgaaca
    13621 tttgaaaaat ctgcttgaaa aaaacgtcgg aaaatttgac cgcactttta tcgttaccga
    13681 atctgttttc agtatggacg gcgatgtggc ggatttgaaa cagcttgtcc aattaaaaaa
    13741 acagtttccc aatacttatc tttatgtgga tgaagcccac gcaatcggtg tttatgggca
    13801 aaacggattg gggattgccg aacgggataa tttgattgcc gagattgatt tattggtcgg
    13861 cactttcggt aaagccttag cctcggtggg ggcgtatgcc gtctgcaacc aagtattgaa
    13921 agaatgtttg attaatcaaa tgcgcccatt gattttttca accgcattgc cgccgtttaa
    13981 tgtggcttgg acttatttta tttttgaacg attgccgcaa ttctcaaaag aaagaagcca
    14041 tcttgagcag ttaagcgcat ttttacggcg ggaagtggcg catcggacgc aaataatgcc
    14101 gagccaaacc tgtatcgtcc cctatatttt aggcgggaat gaagccaccc ttgctaaagc
    14161 ggaataccta caaaggcagg gttattattg cctgcctatc agaccgccga cagtaccaaa
    14221 aggtacatcc agaatacgat tatctttgac ggcagatatg acaatggatg aagtgcggca
    14281 gtttgcggcg tgtctgtaag gatatgatat gaaaacaaaa ttttacgatt gccaaggcgg
    14341 acatttaatc ctgtattttg caggttgggg aacgccgccc gatgctgtaa atcatttgat
    14401 tttgccggaa aatcacgatt tattgatttg ctatgattat caagatttaa atttggattt
    14461 tgatttttcc gcctatcggc acatccgttt ggtggcgtgg tcaatgggcg tttgggcggc
    14521 agagagggca ttgcaaggaa taagattaaa atctgcaacg gcagtgaatg gcacaggttt
    14581 gccttgcgat gataatttcg gtatccctta cgccgttttt aaaggcacat tggagaacct
    14641 cacggaaaat acccgtttaa aatttgaacg cagaatctgt ggcgataaag catcttttga
    14701 acgttaccaa caattttccg cccgtccgtt tgacgaaatt catcaagaac ttaccgcact
    14761 ttttgcgatg atcgggcaag atagacgtac agatcttatc cgctggacaa atgccttggt
    14821 cggatcgggc gataaaattt ttatgtctgc caatcagcac cgatattgga cagcgcgttg
    14881 caccgttcgg gaaattgacg gcggacatta cctgttttca agattcaccc attggtcggc
    14941 actatggaat cactgactgc cataaataaa tcgcgcattc ggcaggcttt ccaaaaagca
    15001 ttaaacgatt atgaccggca cgccttaatc caacaaaaaa tgacgattaa tctaatggcg
    15061 catttgcaag attatttgcc tgatatgcca ttggaaaacg tattggaatt gggctgcggt
    15121 tcaggaatgt tgagtgcctt gctgcaaaaa cagatttcag cgaattattg gttatttaat
    15181 gatttgtgcg atgtgcagcc ccaattggct gaaaaactgc cgcaatcctt tgatttttat
    15241 tgcggtgatg cggaaaactt tccttttcaa cgacaatttg acttaatcgc aagcgcatct
    15301 gccgtgcaat ggtttcatca acccgacgct tttatcgccc attgcaaaac aggcttgaaa
    15361 gcaaacggat tattggcggt tgcaaccttt ggcaaagaca atttaaaaga agtccgccaa
    15421 attacaaata taggcttaaa ttacccgact ttatcccaat ggcagacttg gttagccaaa
    15481 gattttgagc ttttatggtg tgaggatttt aaggtaatac tagactttga tacgccgtta
    15541 gatgtactca aacaccttaa atatacaggc gtaacagcca cgaaccaaaa aaattggaca
    15601 agaaaaaatc tcaatggatt tattggcgat tatttgtcgg cgttcagtat gccgtcgggc
    15661 aaagtgcgcc tgacttatca tccgttattt tttatcgcgc gctactctga ggcgggcagg
    15721 caataaggca gcttatgggc aaagttattt ttatatcggg gattgatact gatgtgggta
    15781 aaaggtaata tggcgaggct tgtgcagaag gcatattgtt aaacgttaaa ttatggtatg
    15841 atttaaaact tacaagtcta tttcagtaaa tcgttaataa taaaagcgga caatggccgt
    15901 tgcaggcggt cagctatccg ctcgttacgg tatcgggagt atcctttgga aaactcatta
    15961 attatcggtt tggcactggc ggtattgctg atgcttttgg ttatgcgtgc gaagcagggt
    16021 aagaaaacac caaagcgcaa atcccaaggt gtcggcaata cgcaggggca gacacccgga
    16081 agcaatgatt cggactgggt cgatcagatt ggacaatcgg tttcagacgg cacgcaaccc
    16141 gactggtctt ggaacgaaag tgccgagacc gcatccgccg ccgtatccgc gcaagaagtc
    16201 gatccgctta cggagtatca ggtttataag caattcggtt atcagggcaa ggctgccgaa
    16261 tctttggctg cctatctgga cggcattccg gatggtgaag cgaaacctga aaaccttatc
    16321 cgcgagctgc tcgatatcaa tctcgaagtg ggggatgtcg atgttttggc agacaatctg
    16381 caaaaatacg gcaaactgat tccttccgaa cttttggcaa aatatatcga acaggcatta
    16441 cagcgcgatt caaaccattt gcgtatccgc gtcttggcgg aagaaggttt gggatggggt
    16501 actcaggaga ttgaaaaacg tgcggaaggc ggttctgcga cggcagcttc cgcatcgccc
    16561 ccgccggatg ccggcggtaa ggcttatgaa gccgaagaaa tcaagcgcat cccgattgtg
    16621 cggggcaaaa aagacgtgtc cggaatcagt caagaggaaa tcggtgcgat tgccggtttg
    16681 gtccgtgccg atcaaggtgc gaaaatcctt aaagacaaag tcagctatga aacggcatcg
    16741 aaacaatacg accgtgccat ccaaacttcc gaaaaacctg caaacctgat tatcgatgcg
    16801 ttgaaactcg attaccaata cgcggacata gaccgttttg ccggacattt gtggaaactt
    16861 taccaaacgt tgggcaacta cggcaggcag gttaaagagc ggatgctggg gtgggggtac
    16921 agcctgggtt accatgaggt tttcgatgat ttggaaaaag ggccgaacga ccggcaaatc
    16981 aaagacatcg gtatggggca cgggtatctg ccgaaaaata tacagaaatt caaatcgcaa
    17041 catcgggatt tggtgcttca agattcttcg ttgatcaaca ccggttcgtc tccggcagac
    17101 gatgcggtta aggaagtaga gtcgttgctg atgtatggtc agattgaagc ggcaatggat
    17161 gtgttggagc aggcggtatt gaaatatccc gacgagtccc agctttatat tacgttgatc
    17221 gatatttatg aacgtactga agattgggat aggttggggc agtttttaag ggtattgagg
    17281 gaacgtgcgg acaggcttcc tgaagaggtc gttatgctga tgagccggct gctgcagcgt
    17341 atgaatcaaa atattaaaaa aataaaacgg tacggaaaat aaaaatggaa gttcaactgc
    17401 cgaaaattaa aacagtacgc gtaatgttgg cggggatgac ggcgcagcag gaatccgttt
    17461 tcaaaatggc attcaaaatg cacaatacca cccgttatga aacagtatcc ccttcagacg
    17521 gcagtgccgt gcccgatttg gttttggcgg ataccgatgc cgagggcggt tttgaacttt
    17581 ggaaagagct tgccgagcgt tataaggata tacccgtcgc cgtctgttcg gagaaagttc
    17641 ccgattctga agttccctac ctgcccaaac cgattcggtt tgaaacattg tttcctatgc
    17701 tccgcaaatt gttgcagggc gagaatgttt atgggaaatc gtttattgca cccgcagacc
    17761 ggtcggcgaa aaataacggg aatgtgcagc gtacggttac gatacgccag tttaacccga
    17821 ataaaggatt attgggggcg ttgcggtttg cggaaaagaa caggcaggac atcgctatct
    17881 tgcatggaaa taagccggtc cttattgttt tcccctcgat acaacgggtt ttgctgacag
    17941 aaagtgtgca aaaactcgaa gaattgtgca aagacgaaaa tttgcaggtc agctgcaaga
    18001 ctgttcccga taacccgcaa tggcgcgaaa aggctaaagt aggcattatg tcctgtatgt
    18061 ggcagttttc catttggaca gcgcagggca ggttgattta tccgatttct cccgatactc
    18121 cgtttacgtt gaaatcttgg ccaaacctga cccggttggc aaatgtgccg gggtcgatac
    18181 gcttgtcggc atttctgacc aaggcatccg tcaaccttaa cgtgttgtat aaagtgatgc
    18241 ctttaaacct caatgatatt ctgaattatc ttgcggcaac ctatacaacc gggtttttgt
    18301 cggtagattt aaaaacggtt tcacaacagg catactccga tatggcggat aaaataaata
    18361 tcggagccga ttctgcctct gatagtgaaa tgatgaaaaa agcggaaaaa atcacaacat
    18421 catcccaatc ccagtcgcgc ggccttctgc aaaggctgat gaaaaaactg ttgggcagct
    18481 aagaggcgga gagatgagag aaaataaaat tattttcaca ggacctgtcg gcgtagggaa
    18541 aaccactgcc attgcggcta tttcggacga agcactcgtt cagaccgatg cttccgcatc
    18601 cgatatgact ttggatagga aaaggaatac gacagtggcg atggactacg gggccatcag
    18661 cttggatgag gataccaaag tccatttata tggtacgccc ggtcaggaac ggttcaactt
    18721 tatgtgggaa atcttaagcc aaggcagtat gggtttggtc ttgcttttag ataatgcccg
    18781 aaccaatccg ttgaaagatt tggaattctt tttacattcg tttcgagggc tgctggagaa
    18841 ggcacccgtc gttgtcggta ttaccaagat ggatatacgc tctcagcccg gtatcgacgt
    18901 gtatcacaaa tatcttgcaa aacataatct taatgttccg gtttttgaaa ttgatgcccg
    18961 taaggaagat gacgtaaaac aattggttag cgcaatgtta ttttctattg atccgggact
    19021 ggaggtttaa tatggaatca acactttcac tacaagcaaa tttatatccc cgcctgactc
    19081 ctgccggtgc attttatgcc gtatccagcg atgcccccag tgccggtaaa actttgttgc
    19141 acagcctgtt gaaagcggat gcggacgaaa tggtcagcag tgagaagctg cttacctggg
    19201 cggacaccgc cgacatcgat accgctttga acctgttgta ccgtttgcaa aaactcgaat
    19261 tcctctatgg cgatgaaaac ggtcattcag acggcatcaa tttgtcggac gagcaattgc
    19321 cgttgctgat ggaacaattg tccggcagcg gtaaggcgtt attggtcgat cggaacggtc
    19381 tgtatcttgc caacgccaat ttccatcatg aggcggcgga agagttgggg ttgttggcgg
    19441 cagaagtcgc acagatggaa aagaaatacc ggctgctgat taagaacaac ctgtatatca
    19501 acaataacgc ttggggcgtt tgcgatcctt ccggtcagag cgaattgaca tttttcccat
    19561 tgtatatcgg ttcaaccaaa tttattttgg ttatcggcgg cattcccgat ttgggcaaag
    19621 aggcatttgt tactttggta aggattttat accgccgtta cagcaaccgc gtgtaaaact
    19681 tgggagagag gaggggttat gcagcaatta ttgatttcaa tccttgaaga tttaaacaat
    19741 acatctacgg atattatcgc gtctgccgtt atctcaaccg acggattgcc gatggcgaca
    19801 atgcttcctt cacatttgaa ttcggacagg gtaggggcga tttctgccac tttgcttgct
    19861 ttggggagtc gctcggtgca ggaactcgcc tgcggggaat tggaacaagt gatgattaaa
    19921 ggaaaatcag gctatatcct tttaagtcag gcgggtaaag atgccgtgtt ggtgctggtg
    19981 gcaaaagaaa ccggcagact tggtttaatc ctattggatg ccaaacgtgc ggcaaggcat
    20041 attgcggaag ccatataaca tataaagatt gcgggcttgc agataaagtg caatcgattg
    20101 tcaatttata ttgacacgtt cggtatttct gttttattat tcgcgcttat tccccgatag
    20161 ctcagtcggt agagcgacgg actgttaatc cgcaggtccc tggttcgagc ccaggtcggg
    20221 gagccaaatt tcaaaaccct ctaagtattt tcttagaggg ttttgtttta ccggcggtca
    20281 gaaacgcatt tttgagatga ttgttttgag atggaataaa atctttgcaa aattcctttc
    20341 gtgatggtta tgaaaaaata ggggctgtcc tggacagcta ggataaactc gattttatag
    20401 tggattaaca aaaaccagta cggcattggc tcgccttagc tcaaagagaa cgattctcta
    20461 aggtgctgaa gcaccgagtg aatcggttcc gtactatttg tactgtctgc ggcttcgtcg
    20521 ccttgtcctg atttttgtta atccactata ctaattgaga cctttgcaaa attcctttcc
    20581 ctcccgacag ccgaaaccca aacacaggtt ttcgtctatt tccgctacca atcactccct
    20641 aattctaccc aaataccccc ttaatcctcc ccggataccc gataatcagg catccgggtt
    20701 accttttagg cggcaacagg cgcacttagc ctgagacctt tgcaaatttg tcggtttcgg
    20761 ggtcgtattg gtagcctcgt gcctgtatgt cttctttgaa agtttcgtat acgtcatggg
    20821 ctaaaagggc tgttccgaca tagggaaccg cccttgtgct gaatttcgcg cctaagcggg
    20881 caagtttgcc gccccccgcc aatacgccgg cgcgggaaat gctggcggtt attttggcgt
    20941 tgattcgggc ttttgcgccc gtagggatgt gtgttaaatc taccgttttt attaaatcag
    21001 atgaataagt tttactattt ttaggtacaa acttatgaat tttcgcacct tgtccggtat
    21061 caactgaaac agtttcagat atttttactg catttgcatt cgcttcaaac gaatacatca
    21121 tcaaaattgc aattatcgac aatttcgcaa aattcaaatt tgtatatttt atgaccatct
    21181 ttcagggatt ctttaattac cttttctgaa ttatcagaaa atgagattag ccaaatatca
    21241 tgtttaattc ttctattcca gaaaaaagag aaacaatcaa taacattttc agacttatta
    21301 atcttcgcaa attcaacaaa ttcagattgc gctataaccg ccatcgattg cccaaaatac
    21361 ttgctagacg gctgatattt ataaagtgcc aactgcgcct gagtgataaa cggcttgttc
    21421 atggttctgc ctttcaatga ttgttttgaa agcctgattt tgacaccata acttcatgcg
    21481 ctcaattctt aaacagaacc gccccgatta atacgggtac ggaaacgccg agataaaaat
    21541 aaaaatccat catttcaaaa cctttttcag cagggaaaca aagtaaacgg acgcgaggat
    21601 gccgaatact atccaacctg tttcaagacc gctttgcagg ttgtctttcg gactgcattc
    21661 cgccaataaa agccttagcg gctgaccgtc cgacatcttc cacaggctgc cgttatattc
    21721 cggcctgaca atctgtccgt tttctttgat tcttggtact accaagctga aataaaggtt
    21781 ttcagcctgg tgcttctcaa gacatttatt tccgacttgg tagtacatgc cgtcttactt
    21841 catcactctc ttaacgatgg aaaacacaaa aagcgcggcg aaaacgccaa cgacaatcca
    21901 accggcttcc ataccgtccg cttttgcggc ttccaaagcg ttttttgccg tatcgggcaa
    21961 cgttgcattt gcatgtgcgg ccaaagccag gggagcagct gttacaacag ccagttttgc
    22021 gccgtattta cggcaggtgt taataaattt catgatattt tcctttaaaa agtgtttggc
    22081 ggtaatggat ggagcgtttt tcagacgacc gccgaacatc cgaaaatcag tctttcaaaa
    22141 atccgaatac gacaaattcg tattggttgc cgatttcttc caaacctgcg ttaatcgctt
    22201 cttcgaagtc gtagaaataa tcggcattgg tgattaattt ggtatgtccg atgtcgcccg
    22261 tttcaggaga gagatacaga aagtcccctg ttgatacgga ctggacaaca tagactttct
    22321 gcattcaatc agcctttctt aacgggttga aaaccgatga ctttcagttt ttgggttttg
    22381 cccgtagtga cgatttctac gttcaggttt gcttcgatcg gaaattgggc gtttcggaac
    22441 tgctcgaaat tggcagagcc gccgaaatcg tattcagtag tagagctgcc caatgcgttg
    22501 ccttgggagc tgtctaaggg tgtggcgaca atcaggcggc aatagtcgaa gctcttgcct
    22561 tcgatttgtc cgttgaattt tttaacgccg acgatgtggc cttgaagttg gatgttcatt
    22621 ttttggtttc cttgtgtgat taaacgtctt tcgggcagac actttaagcc catgaaatcg
    22681 gtagtcttgc gaatttgtcg taaatgaagt tgttatagct ttcttcattg ttgacgtgtt
    22741 tttgctgttc aagctgtttt tcaagattct cgtaatattc gtacatatag taagggtctt
    22801 tgtacggttt gaatgcgggc tgttcatgaa tggcttgagc tttcaaaaag gcgcagtcgt
    22861 aggcttcggg agccaaagac ttgggcagct tgtgatgact cggctcaatc agttcaaaca
    22921 gtttggcttt gtccaattcg ggaaaaatga atttcagacc gtttgccgca cgtccaaact
    22981 gtttttttac ccattcaagg tagcggtcgg ctgaaatgac cttatcttcc ttaaccgcgt
    23041 gtatgcgcgt tgccttttgg acgaatcgtt cgcaaatcgg atatgcgccg ccgaaatatt
    23101 cgcccggatt ctgcaaaact tcaaaaggga taacgatgtc ttttgctttg aattcaattt
    23161 caaagcgcgt ccatgtgctt gttttatcgc ccaactgctt gcctttttca tagacgcgga
    23221 catatttgga cgattcacgg gagccgatac cataggtctt gcctttggtc attttggctt
    23281 catcgtcttc ttcccaatct gaccccaaac attcgccttt tggtttgacg tgatgacagg
    23341 taaacatacc tttatttcgg tcttcacggg cttggttcgg gctgtattcg ccgttgaaaa
    23401 agtcttttgc gatgtcaacg cgtgtgattt ttgggcggat tgcattagtc aggaatgcga
    23461 aaagtcgtga ttcccagcct tcttttgcga cgccgcaacc ggtgccggtc agttcgaaaa
    23521 ggatggtatt gttttgtccg ccaaaatgga cgcgaccgta taggacgtct tccgaaccca
    23581 tcaaccaaca gcgctcataa aaacgaccgc ccgagccttt ggactctttg tagataccga
    23641 aaccgaaaac ttcttcggcg agcatggacg cggcgcgaat gaaatcttcg tcttccaaaa
    23701 gacttacacg aacgccgtat ttatcgaaaa aggttttttc atgaaatgaa aagctaattt
    23761 gatcaatgaa agccgaatct gatacaccgc gccgaagagg aacgcctaac aggtttcctt
    23821 taccgtccgt tatgtacgtt tcgtaacatt cgaagacttc ctgaaccctg cctgccgttt
    23881 cggtttctgt accccccctg ttagataagg ggggaagatt tgaagcggtt gccggcttcc
    23941 tgccgtccgc taacgcgtcc gtcatcacgc cgacaaccgc ctttgtcatc ccttgcttat
    24001 cttccatggt gcgaatcctc aaaaacgggc aaaaaaaagc cctgttactt gtagaaagta
    24061 aagggcgtta atttttgtta
//
LOCUS       DAXISH010000026        24065 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.026, whole genome shotgun sequence.
ACCESSION   DAXISH010000026 DAXISH010000000
VERSION     DAXISH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 24065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24065
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.026"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(86..955)
                     /locus_tag="ACFOV4_001061"
     CDS             complement(86..955)
                     /locus_tag="ACFOV4_001061"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFC7619086.1"
                     /translation="MSANEYTQIGWIGLGQMGLPMVTRLLDGGIEVGVYNRSPDKTAP
                     ISAKGAKVYGNTAELVRDYPVIFLMVSDYAAVCDILNGVRDGLAGKIIVNMSTISPTE
                     NLAVKALVEAAGGQFAEAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTF
                     HFGDVGKGSGAKLVLNSLLGIFGEAYSEAMLMARQFGIDTDTIVEAIGGSAMDSPMFQ
                     TKKSLWANREFPPAFALKHASKDLNLAVKELEQVGNTLPAVETVAASYRKAVEAGYGE
                     QDVSGVYLKLAEH"
     gene            complement(1050..1967)
                     /gene="hisB"
                     /locus_tag="ACFOV4_001062"
     CDS             complement(1050..1967)
                     /gene="hisB"
                     /locus_tag="ACFOV4_001062"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HFC7619087.1"
                     /translation="MNLTKTQRQLHNFLTLAQEAGSLSKLAKLCGYRTPVALYKLKQR
                     LEKQAEDPNARGIRPSLMAKLEKHTGKPKGWLDRKHRERTVPETAAESTGTAETQIAE
                     TASAAGCRSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDID
                     ISCKGDLHIDDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLS
                     GRPGLVYNIEFTRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFK
                     AFGRALRMAVEHDPRMAGQTPSTKGTLTA"
     gene            complement(1964..3061)
                     /gene="hisC"
                     /locus_tag="ACFOV4_001063"
     CDS             complement(1964..3061)
                     /gene="hisC"
                     /locus_tag="ACFOV4_001063"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFC7619088.1"
                     /translation="MKSVRSFIRDDIQAMSAYQIADVPPGFAKLDSMESPVHPFAGHE
                     TLLQEWQARLAAAPIHLYPNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITML
                     TAKPGAAMLAAEPSFVMYRHNAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTF
                     IAYPNNPTGVCFTRAEIEAVIEASDGIVVVDEAYGAFNGDSFLPQAGSIPNLIVMRTV
                     SKIGFAGLRIGYAAGCPEVIGELQKILPPYNMNQLSLTTAKLALQHYGIISANIDSLK
                     NERERMFAELGKICRLNTFPSQANFITIRVPDADLLFDTLKQNRILVKKLHGAHPLLE
                     HCLRITVGSPAQNDAVLNIIRQLYCQPTDFL"
     gene            complement(3107..4396)
                     /gene="hisD"
                     /locus_tag="ACFOV4_001064"
     CDS             complement(3107..4396)
                     /gene="hisD"
                     /locus_tag="ACFOV4_001064"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HFC7619089.1"
                     /translation="MKKLNTQSPDFQAGLKALLAFETAQNPETERIVADICADVQKRG
                     DAALIEYTNKFDQTNAKSIDDLILTQADLNAAFERIPNDVQTALQTAARRVESYHQRQ
                     KMESWSYTDEDGTLLGQQITPLDRVGIYVPGGKAAYPSSVIMNAMPAHVAGVKEIIMV
                     VPTPKGERNDIVLAAAYVAGVTKVFTVGGAQAVAALAYGTETIPQVDKITGPGNAFVA
                     AAKRRVFGVVGIDMVAGPSEILVIADGTTPADWVAMDLFSQAEHDEIAQAILIGTSQA
                     YLDEVEAAMDRLIETMPRRDIIEASLGNRGAMILAKDLDEACEIANYISPEHLELSVE
                     NPQEWAKKIRHAGAIFMGRYTGESLGDYCAGPNHVLPTSRTARFSSPLGTYDFQKRSS
                     LIQVSEQGAQKLGETASVLAHGESLTAHARAAEFRMK"
     gene            complement(4393..5292)
                     /locus_tag="ACFOV4_001065"
     CDS             complement(4393..5292)
                     /locus_tag="ACFOV4_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HFC7619090.1"
                     /translation="MVAKIKKFSDSTLSVLNNGERRFYVYCLTDLKKDKILYIGKGCG
                     NRIFEHEWVASRSQDPVSGEIIDRKLKAISKCKKLGRYIISYHLTEVEALAAESALIH
                     FVKSVLGKKLKNKIAGHGPGGISVEELDRRFGFSSLPLNEINPDGLILAIKIHNAFDL
                     DTDEELDYLFDNQDDANLKSRTLGNWVIGKDVASKVKYVIGVHTGLQNAVVSAYEVDG
                     FETMVEETKNGRKQSRYRFRTTSRSEEVLAKLGLQQKCLPELKFGSGGEKAYIRPKTE
                     TETEQENIQTTPNPKIKKEKTKS"
     gene            complement(5396..6049)
                     /gene="hisG"
                     /locus_tag="ACFOV4_001066"
     CDS             complement(5396..6049)
                     /gene="hisG"
                     /locus_tag="ACFOV4_001066"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HFC7619091.1"
                     /translation="MQDNALTIALSKGRIFEETLPLLAAAGIVPTEEPEKSRKLIIGT
                     NHENIRLVIVRATDVPTYVRYGAADFGIAGKDVLIEHGGTGLYRPLDLEIAKCRMMVA
                     VRKGFDYEAASQPGCRLKIATKYPEIAASHFAGKGVHVDIIKLYGSMELAPLVGLSDA
                     IVDLVSTGNTLKANGLEAVEHIVDISSRLVVNKAALKTKYALLEPIIQAFGGAVKAK"
     gene            complement(6128..6781)
                     /locus_tag="ACFOV4_001067"
     CDS             complement(6128..6781)
                     /locus_tag="ACFOV4_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCO family protein"
                     /protein_id="HFC7619092.1"
                     /translation="MFSVPRSFLPGVFVLAALAACKPQDNSAAQAASSSASASAAENA
                     AKPQTRGTDMRKEDIGGDFTLTDGEGKPFSLSDLKGKVVILSFGFTHCPDVCPTELLT
                     YSDTLKQLGGQAKDVKVVFVSIDPERDTPEIIGKYAKQFNPDFIGLTATGDQNLPVIK
                     QQYRVVSAKVNQKDDSENYLVDHSSGAYLIDKNGEVAIFSPYGSEPETIAADVRTLL"
     gene            7058..7142
                     /locus_tag="ACFOV4_001068"
     tRNA            7058..7142
                     /locus_tag="ACFOV4_001068"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7092..7094,aa:Leu,seq:caa)
     gene            7852..9579
                     /gene="ilvB"
                     /locus_tag="ACFOV4_001069"
     CDS             7852..9579
                     /gene="ilvB"
                     /locus_tag="ACFOV4_001069"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HFC7619093.1"
                     /translation="MQLSGAQIIVQSLKAEGVEYVFGYPGGAVIEIYDALFQLNKFKH
                     ILTRHEQAAVHAADAYARVSGKVGVALVTSGPGVTNALTGIATAYTDSIPMVVISGQV
                     GNSLIGTDAFQEVDTVGITRPCVKHNFLVTDINELAETIKKAFQIAASGRPGPVVVDV
                     PKDVTQAMAKFSYPQEDIFIRSYQPVVQGHIGQIKKAVQMLASAKRPVVYFGGGVVLG
                     NASEELTRFVRMTGAPCTGTLMGLGAYPSSDRQFLGMLGMHGTYEANLAMQNADVVLA
                     VGARFDDRVVSVPSKFFEKAKKVIHIDVDPSSIAKRVKADIPIVGDVKNVLSEMVALW
                     QKQESVPSEDTLGKWWKTIEEWRSRDCLWFDNGSEIIKPQYVIQKLAEITGNSAIITS
                     DVGQHQMFAAQYYPFERPRQWLNSGGLGTMGVGLPYAIGAKLAAPDQDVFCITGDGSI
                     QMNIQELSTCFQYRIPVNVITLNNGYLGMVRQWQEIYYGGRESETYFDSLPDFVKLAE
                     AYGHIGIRVDKKSDVEGALLEALNQKDRLVFIDFLTDQKQNVMPMVGNGKGLDEMVLP
                     PHMRADEKA"
     gene            9590..10081
                     /gene="ilvN"
                     /locus_tag="ACFOV4_001070"
     CDS             9590..10081
                     /gene="ilvN"
                     /locus_tag="ACFOV4_001070"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HFC7619094.1"
                     /translation="MRHILSVLIENESGAMSRVVGLFSARDYNIDSLAVAPTEDKTLS
                     RMTIVTHGDEQVIEQITKQLNKLIEVIKVVDLNESRFVERELMLVKVRAAGKDRDEFL
                     RLTEIYRGSIIDVTDRSYTIEITGSTDKLDSFLETVGRAQILETVRTGAAGIGRGERI
                     LKI"
     gene            10148..10441
                     /locus_tag="ACFOV4_001071"
     CDS             10148..10441
                     /locus_tag="ACFOV4_001071"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004521031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative quinol monooxygenase"
                     /protein_id="HFC7619095.1"
                     /translation="MSNIKIVALVTVKPEYTETLAAQFKELVKASRAEEGNISYDLHQ
                     EIGKPNRFVFVENWKSQAAIDEHNASAHFQAFVQSVDGKTEALEIVLMNEVAA"
     gene            10521..11534
                     /gene="ilvC"
                     /locus_tag="ACFOV4_001072"
     CDS             10521..11534
                     /gene="ilvC"
                     /locus_tag="ACFOV4_001072"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HFC7619096.1"
                     /translation="MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVI
                     GLRQGSSWKKAEAAGHVVKTVAEATKEADVVMLLLPDETMPAVYHAEVTANLKEGATL
                     AFAHGFNVHYNQIVPRADLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDKSGKAK
                     DIALSYAAANGGTKGGVIETNFREETETDLFGEQAVLCGGLVELIKTGFETLTEAGYA
                     PEMAYFECLHEMKLIVDLIYEGGIANMNYSISNNAEYGEYVTGVEVINDKSREAMRNA
                     LKRIQTGEYAKMFIQEGNVNYASMTARRRLTADHQIEKVGAQLRSMMPWIAKNKLVDQ
                     DKN"
     gene            11753..12142
                     /locus_tag="ACFOV4_001073"
     CDS             11753..12142
                     /locus_tag="ACFOV4_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619097.1"
                     /translation="MLYKCKIKKLDNTIEEAVLIEINGYELHCFISYCPFKIFENQFY
                     EVELSYEIFNDYILDKSTSNIGFRKIDDSFKYEITAELKNNHLTLQNIQFEEDKYLIN
                     YSYLDNCLVTLTVDRISVSFIREIQAA"
     gene            complement(12368..13363)
                     /gene="argF"
                     /locus_tag="ACFOV4_001074"
     CDS             complement(12368..13363)
                     /gene="argF"
                     /locus_tag="ACFOV4_001074"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFC7619098.1"
                     /translation="MNLKNRHFLKLLDFTPEEITAYLDLAAELKAAKKAGREIQRMKG
                     KNIALIFEKTSTRTRCAFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDA
                     IEYRGFGQETVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHGGKPLNQTSFAYV
                     GDARYNMGNSLLILGAKLGMDVRIGAPEGLWPSEGIIAAANAVAEETGAKITLTANPQ
                     EAVKGVGFIHTDVWVSMGEPKEVWQERIDLLKDYRVTSELMAASGNPKVKFMHCLPAF
                     HNRETKIGEWIYETFGLNGVEVTEEVFESPAGIVFDQAENRMHTIKAVMVATLGD"
     gene            complement(13505..16090)
                     /gene="acnB"
                     /locus_tag="ACFOV4_001075"
     CDS             complement(13505..16090)
                     /gene="acnB"
                     /locus_tag="ACFOV4_001075"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HFC7619099.1"
                     /translation="MLEAYRKAAAERAALGIPALPLTALQTADLVELLKNPPAGEGDF
                     LVELLAHRVPPGVDDAAKVKASFLAALAEGSASSPLISPEYATELLGTMLGGYNIHAL
                     IELLDDDKLAPIAAKGLKHTLLMFDSFHDVQEKAEKGNKYAQEVLQSWADAEWFTSRA
                     KVPEKITVTVFKVDGETNTDDLSPAPDAWSRPDIPLHALAMLKNPRDGINPDKPGEVG
                     PIKLLEELKAKGHPVAYVGDVVGTGSSRKSATNSVIWHTGEDIPFVPNKRFGGVCLGG
                     KIAPIFFNTQEDSGALPIEVDVSALKMGDVVDILPYEGKIVKNGETVAEFSLKSQVLL
                     DEVQAGGRINLIIGRGLTAKAREALKLPASTEFRLPQAPAESKAGFTLAQKMVGRACG
                     LPEGQGVRPSTYCEPRMTTVGSQDTTGPMTRDELKDLACLGFSADMVMQSFCHTAAYP
                     KPVDVKTHKELPAFISTRGGVSLRPGDGVIHSWLNRLLLPDTVGTGGDSHTRFPIGIS
                     FPAGSGLVAFAAATGVMPLDMPESVLVRFSGKLQPGVTLRDLVNAIPLYAIKQGLLTV
                     AKAGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTVKLNKEPIIEYMKSN
                     VVLMKNMIADGYQDSRTLERRIKAMEKWLANPELLEADKDAEYAAVIEINMDDIKEPI
                     IACPNDPDDVCFMSERSGTKIDEVFIGSCMTNIGHFRAASKLLEGKSDIPVRLWVAPP
                     TKMDAKELSDEGHYGVLGRAGARMEMPGCSLCMGNQAQVHEGATVMSTSTRNFPNRLG
                     KNTFVYLGSAELAAICSKLGKIPTVEEYQANIGIINEQGDKIYRYMNFNEIDSYNEVA
                     ETVNV"
     gene            complement(16300..17370)
                     /gene="lptG"
                     /locus_tag="ACFOV4_001076"
     CDS             complement(16300..17370)
                     /gene="lptG"
                     /locus_tag="ACFOV4_001076"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HFC7619100.1"
                     /translation="MNLISRYIIRQMTAMTVYTLLAFLALYSFFEILYETGNLGKGSY
                     GIWEMLGYTALKMPARTYELMPLATLIGGLLSLGRLAADSELTVIKAGGVSTRKLLSV
                     LSQFGLIFALATAALGEWIAPALNQKAENIKAAAINGKISTGNTGLWLKEQNSIINIR
                     EMLPDHTLLGIKIWERNDKNELVQATEAESAVLNDDGSWQLKNIRRSTLGEDKVETSS
                     AAEENLPISVKRNLMEVLLVKPDQMSVGELTAYISHLENNRQNTQIYAIALWHKLVYP
                     VAAWVMALVALAFTPQTTRHGNMGLKLFGGICLGLLFHFAGRLFGFTARLYGVPPFLA
                     GILPTALFALIGIWLIRKQEKR"
     gene            complement(17367..18482)
                     /gene="lptF"
                     /locus_tag="ACFOV4_001077"
     CDS             complement(17367..18482)
                     /gene="lptF"
                     /locus_tag="ACFOV4_001077"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HFC7619101.1"
                     /translation="MIYQRNLIKELSFTAVGIFVVLLAVLVSTQAINLLGRAADGRVA
                     IDAVLALVGFWVIGMTPLLLVLTAFISTLTVLTRYWRDSEMSVWLSCGLALKQWIRPV
                     MQFAVPFAVLVAVMQLWVMPWAELRSREYAEILKQKQELSLVEAGRFNTLGKRNGRVY
                     FVETFDTESGIMKNLFLREQDKNGNDNIIFAKEGNFSLNNNKRALELRDGYRYSGTPG
                     KADYNRVSFRHLSLIISTTPKLIDPVSHRRTIPTAQLIGSSNPQHQAELMWRISLTVS
                     VLLLCLLAVPLSYFNPRGGHTYNILIAIGLFLIYQNGLTLLFEAVENGKIHFWLGLLP
                     MHIIMFAVALILLRVRSMPARPFWRAVAESLTPKGRK"
     gene            18652..20058
                     /locus_tag="ACFOV4_001078"
     CDS             18652..20058
                     /locus_tag="ACFOV4_001078"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0019538 - protein metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HFC7619102.1"
                     /translation="MEFSTKTEILQEQQAGAQLFVCTEEAQLNHPTALALLSSLEEGQ
                     NFADTKIPTGNGLQAVAVCCLKSTGRAALNKAAAEAAKWAQNQETVNVDIHAFDEAQA
                     AAVAEAFAIAFGNAAYRFDRYKKEAKPAKFETAVFHSAHEAAVKEALRVAEAQVYGQS
                     LCRDLGNAAPNECTPEFLARTAKAEAEKLGAHAKIIEKDYIKENMGSFWSVAKGSAEA
                     PYLVELSYFGAADKEAAPVVLVGKGITFDTGGISLKPGLNMDEMKFDMCGAATVISTF
                     CAAVKLQLPINLIAVVATCENMPSGAANKPGDVVKSMKGLTIEVLNTDAEGRLILCDA
                     LTYAEQFKPKAVIDVATLTGACIVALGHDVSGVMGNNQDLIDSLLAASYNVDDKAWQL
                     PLFETYKDQLKSNFADIPNIGTPGAGTITAATFLSYFTEDYPWAHLDIAGTAWKSGAE
                     KGATGRPVPLLLNYLRNL"
     gene            20121..20561
                     /locus_tag="ACFOV4_001079"
     CDS             20121..20561
                     /locus_tag="ACFOV4_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HFC7619103.1"
                     /translation="MPKATFYTHVAQVPIFTCRLIARAIRDGGRILVWSDSFGQLQEL
                     DKMLWQYEAESFIPHEIWETEEAMPSETSVLLACGGNLPRIPEGMTVLNLSDGFWNTA
                     PVLPARVLEIVGNSLEDLADARERFTAYRRSGFAIEHHGMEGKA"
     gene            20820..21638
                     /locus_tag="ACFOV4_001080"
     CDS             20820..21638
                     /locus_tag="ACFOV4_001080"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFC7619104.1"
                     /translation="MNTIFKISALTLSAALALSACGKKEAAPASASEPAAASSAQGDT
                     SSIGSTMQQASYAMGVDIGRSLKQMKEQGAEIDLKVFTEAMQAVYDGKEIKMTEEQAQ
                     EVMMKFLQEQQAKAVEKHKADAKANKEKGEAFLKENAAKDGVKTTASGLQYKITKQGE
                     GKQPTKDDIVTVEYEGRLIDGTVFDSSKANGGTVTFPLSQVIPGWTEGVQLLKEGGEA
                     TFYIPSNLAYREQGAGDKIGPNATLVFDVKLVKIGAPENAPAKQPAQVDIKKVN"
     gene            21745..22371
                     /gene="purN"
                     /locus_tag="ACFOV4_001081"
     CDS             21745..22371
                     /gene="purN"
                     /locus_tag="ACFOV4_001081"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFC7619105.1"
                     /translation="MKNIVILISGRGSNMQAIVNAAIPNVRIAAVLSNSETAAGLQWA
                     AERGIPTDSLNHKNFESRLAFDTAMMEKIDAYQPDLVVLAGFMRILTPEFCAHYEGRL
                     MNIHPSILPSFTGLHTHERALEAGCRVAGCTIHFVTAELDCGPIVSQGIVPILDGDTA
                     DDIAARVLAVEHKLYPKAVADFAAGRLIIEGNRVRNSENADAARFLTA"
     gene            22387..23058
                     /locus_tag="ACFOV4_001082"
     CDS             22387..23058
                     /locus_tag="ACFOV4_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3108 domain-containing protein"
                     /protein_id="HFC7619106.1"
                     /translation="MMKTFKNIFSAAILSAALPCAYAAGLPQSAVLHYSGSYGIPATM
                     TFERSGNAYKIVSTIKVPLYNIRFESGGTVVGNTLHPTYYRDIRRGKLYAEAKFADGS
                     VTYGKAGESKTEQSPKAMDLFTLAWQLAANDAKLPPGLKITNGKKLYSVGGLNKAGTG
                     KYSIGGVETEVVKYRVWRGDDTVMYFFAPSLNNIPAQIGYTDDGKTYTLKLKSVQING
                     RAAKP"
     gene            23176..23598
                     /locus_tag="ACFOV4_001083"
     CDS             23176..23598
                     /locus_tag="ACFOV4_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HFC7619107.1"
                     /translation="MQVTSKWIDGMCFVGTTEGGHSVVMEGSAAEGAAKRGPSPLEML
                     LLGVAGCSSIDVVMIAEKQRQKVTDCRATVTAKRADDAPRVFTEIHIHFKVFGHDLKE
                     SAIERAVQMSAEKYCSASIMLGKAAKITHSFEIAGADK"
BASE COUNT         5616 a         5921 c         6622 g         5906 t
ORIGIN      
        1 tcataatcgg gactgatttt aagcgtgggg tgataaaaat gccgtctgaa atatgttcag
       61 acggcattgt gtttggaaaa ggcaatcagt gttctgccaa tttcaggtaa acgccggaaa
      121 cgtcctgttc gccgtagccg gcttcgactg ctttgcggta gctggcagca acggtttcga
      181 cggcgggcag ggtgttgcct acctgttcaa gctctttgac ggcgaggttg aggtctttgg
      241 aggcgtgttt gagggcgaag gcgggtggga attcgcggtt tgcccacagg gattttttgg
      301 tttggaacat gggcgagtcc attgccgagc cgccgatggc ttcgacgatg gtgtcggtat
      361 cgatgccgaa ctgccgcgcc atcagcatcg cttcgctgta cgcttcgccg aaaatgccca
      421 agagcgagtt caagacgagt ttcgcgcccg aacctttgcc gacatcgccg aaatggaagg
      481 tttttttgcc gacgagggaa aatatttttt gcagcgggtt taaaacggct tcgctgccgc
      541 cgaacagaat cagcagcgtg ccgttggtgg cgggcccgac cgatccggaa acgggtgctt
      601 cggcaaactg tccgcctgcg gcttcgacaa gtgctttgac ggcgaggttt tcggtcgggg
      661 agatggtgct catgttgacg atgattttgc cggccaatcc gtcgcggact ccgttcagga
      721 tgtcgcacac ggcggcatag tcggaaacca tcaggaaaat gacgggatag tcgcggacga
      781 gttcggcggt gttgccgtaa acttttgcgc ctttggcgga gatgggggca gttttgtcgg
      841 gcgagcggtt gtatacgccg acttcgatgc cgccgtccaa gagccgcgtt accataggca
      901 gacccatttg ccctaagcct atccagccga tttgtgtgta ttcgtttgcg gacatgatgt
      961 ttactccttt tctgtttgta gtgtagtgta atcttatctg ttccgatacc gtctgaaaag
     1021 cctgcgggtg tttcagacgg tatggttttt tatgcggtca gcgtgccttt ggtcgagggg
     1081 gtctgtcctg ccatgcgcgg gtcgtgttcg actgccatac gcagggcgcg cccgaaggct
     1141 ttgaatacgg tttccgcctg atggtgggcg tttttgccgc tgaggttgtc gatgtgcagg
     1201 gtcatcatac tgtggttgac gatgccgtgg aaaaattctt caaacaaatc gacatcgaaa
     1261 cgtccgatta gtgcgcgggt aaattcgatg ttgtacacga gtccggggcg gccggaaagg
     1321 tcgatgacga cgcggctgag ggcttcgtcg agcgggacgt aggaatgtcc gtaacggcgg
     1381 atgccttttt tgtcgccgag tgcctgccgg attgcttgtc cgagtgtgat gccgatgtct
     1441 tcggcggtgt ggtggtcgtc gatgtgcagg tcgcctttgc agctgatgtc gatgtcaatc
     1501 atgccgtggc gggcgatttg atcgatcatg tgttcgagga agggtacgcc ggtatccagc
     1561 ctgcttttgc cgctgccgtc gaggttgatg gagacggtga tttgggtttc gcaggtattg
     1621 cggttgacgg taacgctgcg gcagccggca gcagatgcgg tttcggcaat ttgggtttcg
     1681 gcagttccgg tgctttctgc ggcggtttcg gggacagtgc gttcgcggtg ttttctgtcg
     1741 agccagcctt tgggtttgcc ggtgtgtttt tcgagttttg ccatcaggct gggacggatg
     1801 ccgcgtgcat ttgggtcttc tgcctgcttt tcaaggcgtt gtttgagttt gtagagtgcg
     1861 acgggggtac ggtagccgca gagtttggcg agcttggaca gcgaacctgc ttcttgggcg
     1921 agggtcagaa agttgtgcag ttggcgttgt gttttagtca aattcatagg aaatccgttg
     1981 gttggcagta aagttggcga atgatgttga gaacggcatc gttttgtgcg gggctgccta
     2041 cggtaatgcg caggcagtgt tccaaaagcg ggtgcgcgcc atgcagtttt ttaaccaaga
     2101 tgcggttttg tttgagcgtg tcaaacaaca aatcggcatc gggtacgcgt atggtaatga
     2161 agtttgcctg acttggaaag gtgttcagac ggcatatttt gcccaattcg gcgaacatcc
     2221 gttcgcgttc gtttttcagg ctgtcgatgt tggcagagat gatgccgtag tgttgcaggg
     2281 cgagtttggc ggtggtcagg ctcagttggt tcatattgta gggcggcagg attttttgca
     2341 gttcgccgat gacttcggga cagcctgccg catagccgat acgcagtccg gcaaaaccga
     2401 ttttgctgac ggtacgcatg acgatgaggt tgggaatgct gcccgcctgc ggcaggaagc
     2461 tgtcgccgtt gaatgcgccg taggcttcgt cgacgacgac gatgccgtct gaagcttcga
     2521 tgacggcttc gatttcggca cgcgtgaaac atacgccggt ggggttgttg gggtaggcga
     2581 taaaggtcag ggcagggcgg tgcttcctga cggcttcgag gacggcgggc aggttgaggg
     2641 tgaaatctcc gttcagtgga acgccgacat aatccatgcc gtacagcgcg gcgttgtggc
     2701 ggtacatgac gaaactgggt tcggctgcca acattgccgc gcccggtttg gcggtcagca
     2761 tcgtgatgaa ctgtatcagc tcgtccgagc cgttgcccag cgcgatgtcg gcgcagtcgg
     2821 gaatgtcgaa cgccgaacgt aatgcttcct gtaaaccgct gccggaggga ttggggtaaa
     2881 gatggatggg cgcggcggca agccgtgcct gccattcctg caacagcgtt tcatgtccgg
     2941 caaaagggtg gacgggactt tccatcgaat cgagtttggc aaagccgggc ggaacgtcgg
     3001 caatctgata tgccgacata gcttgtatgt cgtcgcggat gaaggagcgg acggatttca
     3061 tcgtgtttcc ttaatggttg gaatatgcct gtacgccgtt tcggcattat ttcatacgga
     3121 actctgccgc gcgggcgtgg gcggtcaggc tttcgccgtg tgccagcacg ctggcggttt
     3181 cgcctaattt ttgcgcgccc tgttccgaaa cctgaatcag gctggagcgt ttttggaaat
     3241 catatgtccc caaaggcgag gaaaagcggg cggttcggct ggtgggcaat acatggtttg
     3301 gaccggcgca gtagtcgccg aggctttcgc cggtgtagcg tcccatgaaa atcgcaccgg
     3361 cgtggcggat ttttttcgcc cattcctgcg gattttcgac tgacagttcc aagtgttcgg
     3421 gggaaatgta gttggcgatt tcgcaggctt cgtccaagtc tttggcgagt atcatcgcgc
     3481 ccctgttgcc gagcgaggct tcgatgatgt cgcggcgcgg catagtttcg atcaggcggt
     3541 ccatagcggc ttctacttcg tcgagatacg cttgcgacgt gccgattaag atggcttggg
     3601 caatttcgtc gtgttcggcc tggctgaaca aatccatcgc cacccaatcg gcaggtgtcg
     3661 tgccgtcggc gatgaccagg atttcagacg gccccgccac catgtcgatg ccgaccacgc
     3721 cgaacacgcg gcgtttggcg gcggcgacga aggcgttgcc cggaccggtg attttatcga
     3781 cttgggggat ggtttccgtg ccgtaggcga gggcggcaac cgcctgcgcg ccgccgacgg
     3841 tgaagacttt ggttacgccg gcgacgtatg cggcggcaag cacgatgtcg ttgcgttcgc
     3901 ctttcggtgt cggcacgacc atgatgattt ctttcacgcc tgcgacgtgg gcgggcatgg
     3961 cgttcatgat gacggaactc ggatatgccg ccttgccgcc ggggacgtaa atgccgacgc
     4021 ggtcaagcgg ggtaatctgt tgtcccaaca gcgtgccgtc ttcatcggtg tagctccacg
     4081 attccatttt ttggcgttgg tggtagcttt cgacacggcg ggcggcggtc tgcaatgccg
     4141 tctgaacgtc gttcggaatg cgctcgaacg ccgcgttcaa atcggcttgc gtgagtatta
     4201 aatcatcgat gcttttagcg tttgtctgat cgaatttgtt ggtgtattca atcaaagccg
     4261 catcgccgcg cttttgcacg tcggcgcaaa tgtcggcgac gatgcgttcg gtttcggggt
     4321 tttgcgcggt ttcaaaagcc agcagggctt tgagtccggc ttggaaatcg ggcgattggg
     4381 tgttgagttt tttcatgatt tggttttttc cttttttatt tttggattgg gggtcgtctg
     4441 aatattctct tgttcagttt ctgtctctgt tttgggtctg atatacgctt tttctccccc
     4501 gctaccaaac ttcaattcgg gcaggcattt ttgttgcaga ccgagtttgg ctaatacctc
     4561 ttcgctacga gaggtagtgc ggaaacggta acgggattgt tttctaccgt ttttggtttc
     4621 ctcaaccatt gtttcaaaac cgtccacttc gtatgcactg acaacagcgt tttgcagacc
     4681 ggtgtgaacg ccgataacgt atttcacttt tgaagcaaca tctttaccga taacccagtt
     4741 gcccaacgta cgcgatttga ggttggcatc gtcttggttg tcgaaaaggt agtctaattc
     4801 ttcgtcagta tctaaatcga aagcattgtg gattttgatg gcgagaatca gcccgtcggg
     4861 gttaatctcg ttaagtggga gagaagagaa tccaaagcgg cgatctagtt cttctacgct
     4921 aataccaccc ggaccatgcc cggcaatttt atttttgagt tttttaccca agacagattt
     4981 aacaaaatga attaaggcag attcggcggc gagtgcttcg acttcagtca gatgatagct
     5041 gatgatatag cgaccgagtt tcttgcattt ggagatggct ttgagtttcc gatcgataat
     5101 ctcgccggag actgggtctt gtgaacgact agcaacccat tcatgctcga agatacgatt
     5161 accgcagcct ttgccgatgt agaggatttt gtcttttttc aggtcggtca gacaatagac
     5221 ataaaaccga cgctcgccgt tattcaaaac ggaaagggtt gaatctgaga atttttttat
     5281 ttttgcaacc attttaactt ctcctataca gtttactgcc ggtgatattt tcagacgacc
     5341 tgtcggcggg aacggatagg gtcgtctgaa aacgcatctt tattcaaatg gatgcttact
     5401 tcgccttcac tgcgccgccg aacgcctgaa taatcggctc cagcagcgcg tatttcgttt
     5461 tcaaagcagc cttgttgacc accaggcggc tggaaatgtc gacgatgtgt tcgactgctt
     5521 ccaagccgtt tgccttcaag gtgttgcccg tcgaaaccaa gtccacaatc gcatcgctca
     5581 agccgaccag cggcgcaagt tccatcgagc cgtacagttt gataatgtcc acatggacac
     5641 ccttgccggc aaaatgagat gccgcgattt caggatactt cgtggcaatc ttcagacggc
     5701 atccgggttg cgaagctgct tcgtaatcaa accctttacg cacagcaacc atcatgcggc
     5761 acttggcaat ctccaaatcc aaaggccggt aaagccccgt gccgccgtgt tcgatcagca
     5821 cgtctttgcc cgcaatgccg aagtccgccg cgccgtagcg gacataagtc ggcacatcgg
     5881 ttgcgcggac aatgacaagg cggatgtttt catggttcgt cccgataatc agcttgcgcg
     5941 atttttcagg ctcttcagtc ggaacaatgc cggcagcggc aagcagcggc agcgtctcct
     6001 caaaaatgcg ccccttggat aaggcgatgg tcaaagcatt atcctgcatg gtgtggatgt
     6061 cctttgtcgg ttgaaacaat aatgccgtct gaataggcgc cgacggtgca gacggcatac
     6121 ggttttatca gagcagagtc cttacatcgg cagcaatcgt ttccggctcg cttccgtaag
     6181 gcgagaaaat ggcaacctca ccgtttttgt cgatgagata cgcaccggaa gagtggtcga
     6241 ccaaatagtt ttcgctgtcg tctttttgat tgactttggc agaaaccacg cggtattgct
     6301 gcttgatgac cggcaggttt tggtcgcccg ttgccgtcag accgataaag tccggattga
     6361 actgtttggc atacttgccg atgatttcag gcgtgtcgcg ttccggatcg atgctgacga
     6421 acaccacttt cacgtcctta gcctgcccgc ccaactgctt caacgtgtcg ctgtacgtca
     6481 aaagctctgt cgggcagaca tcgggacagt gcgtaaagcc gaaagacaga atcacgacct
     6541 tgcctttcaa atcgctcagg ctgaaaggct tgccttcgcc gtcggtcagc gtgaaatcgc
     6601 cgccgatgtc ttccttacgc atatccgtac cgcgcgtttg cggctttgcc gcattttccg
     6661 cagctgacgc ggatgcactt gaagaagcgg cttgcgccgc actgttgtct tgaggtttgc
     6721 aggcggcaag cgcggcaagt acgaaaacgc ccggcaaaaa ggaacgcggt acggaaaaca
     6781 tgacaatctc ccaagaataa atagcaaaac ctgattcgta cggaatttga atatttccat
     6841 cttaacgcgt ttggcagatt taatgtagta tttttttacg ttgtctgcac ggcaggaatt
     6901 gccgaatcat acagaatctt tggagcggaa agaacagtaa gattaaaata ataaaaattc
     6961 tatttaaaat caaaaataaa ataaaaacag ataaaataat ttcaaaaaaa aggtttacag
     7021 aatttcaaaa gccattataa tgacgacttc ttcaccagcc caggtggcga aattggtaga
     7081 cgcaggggac tcaaaatccc ccgccgcaag gtgtgtcggt tcgagtccga ccctgggcac
     7141 cacaaccgct tttagagcgg ttattttttt gtctattgct gtttaatgaa atagataaga
     7201 ctaaatatag tggattaaat ttaaaccagt acggcgttgc ctctccttgc cgtactattt
     7261 gtactgtctg cagcttcgtc gccttgtcct gatttttgtt aatccactat acaatcaata
     7321 tattaagtcg ttgttagccc tcttggttct gtcaatgccg tccaatacag tccggtgcaa
     7381 tgagccattt tcaggaagta tggttgggaa tatttttgat atatcaaaaa tgaaatcaag
     7441 ttcaatcaat atcccgagtc tttattggga tgaaaccctg taaattttac aattcttgat
     7501 atcgaagaag ggtttttcac atctgcccct cctacacaaa ctgtcaacaa tttccatctt
     7561 tcaaaaaagg tactcctgat tttattcttt taaaatcaat caataatttc tctgctttca
     7621 aaaaatatta taaagatgaa agatttttct tgattgaact gtcggtttgc gttatcgttt
     7681 ccactctttt tcacaaactc tgtgttcctt tccaattgat tggataatcc gtctgttgcc
     7741 gtgttccccc aatgcgcgta ccctaaatcg ctgcttggtg gaattgcatt acaggtgctg
     7801 tggcaaagcg gtttgtccct attggtttga aaccgtataa aagaggtcgt tatgcagcta
     7861 tcaggcgcgc aaatcatagt gcagagtctc aaagccgaag gtgtcgagta cgttttcggt
     7921 tatcccggcg gtgcggttat cgaaatctac gatgcccttt tccaactcaa taaattcaag
     7981 cacattctga cccgtcacga gcaggcggca gtacacgcgg cagatgcgta tgcgcgcgtc
     8041 agcggtaagg tgggcgtggc attggttaca tccggcccgg gcgttaccaa tgcactgacc
     8101 ggtattgcta ctgcctatac ggattcgatt ccgatggtgg tcatcagcgg gcaggtaggc
     8161 aattccctga ttggtacgga tgcgttccaa gaagttgata cggtgggtat tacccgtccg
     8221 tgcgtcaaac acaatttctt ggttacggat atcaatgagt tggcggaaac cattaaaaag
     8281 gcgttccaaa ttgccgcaag cggccgaccg gggcctgtgg tggttgatgt cccgaaagat
     8341 gttacgcagg cgatggcgaa attcagctat cctcaggaag acatttttat ccgttcgtat
     8401 caaccggttg ttcaagggca tatcggtcag attaaaaagg ccgtgcagat gttggcatct
     8461 gccaaacgtc cagtcgtcta ttttggcggc ggcgtggtgt tgggtaatgc ttctgaagag
     8521 ctgacccgat ttgtccgaat gacgggtgct ccgtgcacgg gtacgctgat gggcttgggc
     8581 gcttatcctt ccagcgaccg ccaattcctc ggtatgctcg gtatgcacgg tacttacgag
     8641 gcaaaccttg ccatgcagaa tgcggatgtc gttcttgccg taggtgcgcg ttttgacgac
     8701 cgtgtggttt ccgtaccgtc caaatttttc gagaaggcga agaaggttat ccatatcgat
     8761 gtcgatcctt ccagcatcgc caaacgcgtg aaggcggaca ttccgattgt cggcgacgtg
     8821 aaaaacgttt tgtccgagat ggttgcgctg tggcaaaaac aagagtccgt gccgtctgaa
     8881 gatactttgg gcaaatggtg gaaaaccata gaggaatggc gttcccgaga ttgcttgtgg
     8941 tttgacaacg gcagcgaaat tatcaagccc caatatgtga ttcagaagct tgccgagatt
     9001 accggcaatt cggcaatcat cacatcggat gtagggcagc atcaaatgtt tgcggctcaa
     9061 tattatccct tcgaacgtcc gcgccaatgg ctcaattccg gcggtttggg tacgatgggc
     9121 gtgggtctgc cttatgcgat tggtgcaaaa cttgccgccc cggatcaaga cgtattctgt
     9181 attaccggcg acggctcgat tcagatgaac atccaagagt tgtccacctg tttccaatat
     9241 cggattccgg ttaacgtcat tacgctgaac aacggttatc tcggtatggt acgccagtgg
     9301 caggaaatat attacggcgg ccgagagtcg gaaacttatt tcgattcttt gcccgatttc
     9361 gtcaaacttg ccgaggcata cggtcatatc ggcatccgcg tggacaagaa gtctgatgtg
     9421 gaaggtgcgt tgttggaagc attgaaccaa aaagacaggc tggtgtttat cgacttcctg
     9481 accgaccaga aacagaatgt gatgcccatg gtcggtaacg gcaaaggttt ggacgaaatg
     9541 gtacttccgc cgcatatgcg tgcggacgaa aaggcgtaag gagaggcaaa tgcgacatat
     9601 cttatctgtt ctgattgaaa acgaatcagg tgcgatgagc cgcgtggtcg gtttgttctc
     9661 tgcacgcgat tacaatatcg attctttggc ggttgcgccg accgaagaca aaaccctgtc
     9721 ccgtatgacc atcgttaccc acggcgacga gcaggtcatc gaacaaatca ccaagcaact
     9781 caataaattg attgaagtga ttaaagtggt cgatttgaac gaaagccgtt ttgtcgaacg
     9841 cgaactgatg ttggtaaaag tccgtgccgc cggcaaagac cgcgacgaat ttttacgctt
     9901 gaccgaaatc taccggggca gcatcatcga cgtaaccgac cgcagctata cgattgaaat
     9961 taccggctcg acagacaagc tggattcctt tttggaaacg gtcggacgcg cccaaatttt
    10021 ggaaaccgta cgcacaggcg cggccggcat cggtcgcggt gagcgtattt tgaaaattta
    10081 acgccgtaac ctttcagacg gcacggtatt tgaatgtcgt ctgaaaaacg aacggcagga
    10141 gagatttatg tcgaacatta aaattgtcgc actggttacc gtcaaaccgg aatacacaga
    10201 aacactggca gcacagttta aagaactggt caaagccagc cgtgcagaag agggcaacat
    10261 cagctacgat ctccatcagg aaatcggcaa accgaaccgt tttgttttcg tggaaaattg
    10321 gaaatcccaa gcagctattg acgaacataa cgccagcgcg catttccaag ccttcgtcca
    10381 gtccgtcgac ggcaaaaccg aagcgttgga aatcgtattg atgaatgaag ttgccgctta
    10441 agcggcacac tctgtttaac ccgtccgaag ccgctcaaca ttttaaggct tcgacaacca
    10501 tttaccttaa aggaaatcaa atgcaagtct attacgataa agatgccgat ctgtccctga
    10561 tcaaaggcaa aaccgttgcc atcatcggtt acggttcgca aggtcatgcc catgccgcca
    10621 acctgaaaga ttcgggtgta aacgtggtga ttggtctgcg ccaaggttct tcttggaaaa
    10681 aagccgaagc agccggtcat gtcgtcaaaa ccgttgctga agcgaccaaa gaagccgatg
    10741 tcgttatgct gctgctgcct gacgaaacca tgcctgccgt ctatcacgcc gaagttacag
    10801 ccaatttgaa agaaggcgca acgctggcat ttgcacacgg cttcaacgtg cactacaacc
    10861 aaattgttcc gcgtgccgac ttggacgtga ttatggttgc tcccaaaggt ccgggtcata
    10921 ccgtacgcag tgaatacaaa cgcggcggcg gcgttccttc cctgattgcc gtttaccaag
    10981 ataaaagcgg caaggccaaa gacatcgccc tgtcttacgc ggcagccaac ggcggcacca
    11041 aaggcggcgt gattgaaacc aacttccgcg aagaaactga aaccgacctc ttcggcgaac
    11101 aagccgtatt gtgcggcggc ttggtcgaat tgattaaaac cggctttgaa accctgaccg
    11161 aagcaggcta cgcgcccgaa atggcctact tcgaatgcct gcacgaaatg aagctcatcg
    11221 ttgatttgat ttacgaaggc ggtatcgcca acatgaacta ctccatttcc aacaatgcgg
    11281 agtacggcga atacgttacc ggtgtggaag tcatcaacga caaatcgcgc gaagctatgc
    11341 gtaatgccct caaacgcatc caaaccggcg aatacgccaa aatgttcatc caagaaggta
    11401 atgtaaatta cgcatctatg actgcccgcc gccgtctgac tgccgatcac caaatcgaaa
    11461 aagtcggcgc gcaactgcgt tctatgatgc cttggattgc caaaaacaaa ctggtcgatc
    11521 aagacaaaaa ctgattcttc ccaatcgttc aaactgcctg tctgatgaca ggcagttttc
    11581 ttatgtgcgg cttttaaagg ttccggcttt ttccatcatt ctaaatttat ttttgttgga
    11641 accaatgaaa atggtagtat taccacgata catacaaaat caggaaaaga cttttggaga
    11701 actttgaata acaatccaaa aaacaaaaca atttatccaa aggcaagata aaatgttata
    11761 taaatgtaaa atcaaaaagt tagataacac cattgaagag gcggtattga ttgaaataaa
    11821 tggttatgaa ctacattgtt ttatatcata ctgcccattc aaaatatttg aaaatcaatt
    11881 ttatgaagtg gaattatcct atgaaatctt taatgattac atactggata aatcaacttc
    11941 aaatattgga tttagaaaaa tagatgatag tttcaagtat gaaataacgg cagaattaaa
    12001 aaataatcat ctaaccctac aaaatataca atttgaagaa gataagtatt taataaacta
    12061 ctcttatctt gataattgtt tggttacatt aacggttgat agaataagtg tttcatttat
    12121 tagagaaatt caggcagcct gaaacctgtt gtggataccg ttggcagttt agcgattggt
    12181 tatgccacag gaggcaatgc tggggctttt actggtgcga attagcaaag cggggcggat
    12241 aagatgatat agtggattaa caaaaatcag gacaaggcgg cgaagccgca gacagtacag
    12301 atagtacggc aaggcgaggc aatgccgtac cggtttttgt taatccacta tattccggaa
    12361 aacggtatca gtcgcccaaa gtcgcaacca tcaccgcttt aatcgtgtgc atccggtttt
    12421 ccgcttggtc gaacacgatg ccggccgggc tttcaaatac ttcttccgtt acttccacgc
    12481 cgtttaagcc gaaggtttcg taaatccatt cgccgatttt ggtttcgcgg ttgtggaagg
    12541 cgggcaggca gtgcatgaat ttgaccttcg ggttgcccga tgccgccatc aactcggagg
    12601 taacgcggta atcttttaat aaatcaatgc gttcctgcca tacttctttc ggctcgccca
    12661 tactgaccca tacgtcggta tggatgaaac cgacaccttt gacggcctct tgcgggttcg
    12721 cggtcagggt aatttttgcg ccagtttctt cggcgacagc gtttgcggcg gcaataatgc
    12781 cttcagacgg ccacaggcct tccggtgcgc cgatacgtac gtccatcccc aattttgccc
    12841 ctaaaatcag cagggaattg cccatgttgt aacgcgcgtc gccgacatag gcaaatgagg
    12901 tttggttcaa aggtttgccg ccgtgttcgc gcatagtcag tgcgtcggca agcatttgag
    12961 tggggtggaa ctcgttggtc agaccgttga atacgggtac gccggcatat ttcgccaatt
    13021 cttcgacggt ttcctgaccg aagccgcgat attcgatggc atcgtacatc ctgcccaaga
    13081 cgcgggcggt gtctttgatg ctttctttat gcccgatttg gctggcggac ggttccagat
    13141 aagtaacccc cgcgccttgg tcgcgtgcgg caacttcaaa cgcgcaacgt gtgcgggtcg
    13201 aagttttttc aaaaatcagg gcgatgtttt tccctttcat ccgttggatt tcacgccctg
    13261 cctttttggc ggctttcaat tcggcggcaa ggtcgaggta ggcggtgatt tcttccggcg
    13321 taaagtctaa aagtttcaga aaatggcggt ttttcaggtt cactgtcgtt tcctttatgt
    13381 gggggcgtga acgccgtatt ttcagcgttt gcggaaagaa gggttagcgg aatgttgcaa
    13441 tgccgtctga aggttgttca gacggcattg cggtcaatcc cttactccat acggaaggcg
    13501 gggatcaaac attcacggtc tcggctactt cgttgtagct gtcgatttcg ttgaagttca
    13561 tatagcggta gattttatcg ccctgttcgt tgatgatgcc gatattggcc tgatattctt
    13621 caacggtcgg gattttaccc agtttggagc aaatcgctgc caattccgcc gaaccgaggt
    13681 aaacaaaggt atttttaccc aaacggttcg ggaagttgcg ggtcgaagtg gacatgacgg
    13741 ttgcgccttc gtgtacttgg gcttggttac ccatacacaa tgagcaaccc ggcatttcca
    13801 tacgcgcgcc tgcacggccg agcacaccgt agtgaccttc gtcggacaac tctttcgcgt
    13861 ccattttggt cggcggcgca acccacaagc ggacggggat gtcgctcttg ccttccaaaa
    13921 gtttggaggc ggcgcggaag tggccgatgt tggtcataca agaaccgatg aacacttcgt
    13981 cgattttggt gccggagcgt tcggacataa agcatacatc gtccggatcg ttcgggcagg
    14041 cgataatcgg ctctttgatg tcgtccatgt tgatttcaat cacggcggcg tattcggcat
    14101 ctttatccgc ttcgagcaac tcgggatttg ccagccattt ttccatagcc ttgatgcggc
    14161 gttccagagt gcgcgaatct tgatagccgt cggcaatcat gtttttcatc aacacgacgt
    14221 tggatttcat gtactcgata atcggctctt tgttgagctt cacggtacag ccggcggcgg
    14281 agcgttcggc ggatgcgtcg gtcaattcaa aggcttgttc cactttcaaa tcgggcaggc
    14341 cttcgatttc gagaatgcgg ccggagaaga tgtttttctt accggctttg gcaacggtca
    14401 gcaaaccttg tttaatcgcg tacagcggaa tggcgtttac caaatcgcgc agggttacgc
    14461 ccggttgcag tttgccgctg aatcgtacca atacggactc gggcatatcg agcggcatta
    14521 cgcccgttgc ggcggcaaag gcaaccaagc cggagccggc ggggaaggaa ataccgatgg
    14581 ggaatcgggt gtggctgtcg ccgccggtgc cgacggtatc gggcagcagc aggcggttga
    14641 gccacgagtg gatgacgccg tcgcccggac gcagggacac gccgccgcgg gtggaaatga
    14701 aggcaggcag ttctttatgg gttttcacat cgacaggttt cggataggcg gcggtgtggc
    14761 agaaagactg cattaccata tcggcggaga agcccaaaca agccaagtct ttcaactcgt
    14821 cgcgggtcat cgggccggta gtgtcttgcg agccgaccgt cgtcatacga ggttcgcagt
    14881 aagtactcgg gcgcacgcct tgtccttcag gcagaccgca ggcacggccg accatttttt
    14941 gtgccaaggt gaaaccggct ttgctctcgg caggtgcttg aggcaggcgg aattcggtgg
    15001 aagcaggcag tttcagggct tcgcgcgctt tggcggtcag accgcggccg ataatcaggt
    15061 tgatacggcc gccggcttgc acttcgtcca acaatacttg cgatttcagg ctgaactcgg
    15121 caacggtttc gccgtttttc acgattttgc cttcataagg caggatatcg acgacatcgc
    15181 ccattttcag cgcggaaaca tcgacttcaa tcggcaatgc gccggaatct tcttgggtat
    15241 tgaagaaaat cggcgcaatt tttcctccca ggcatacgcc gccgaaacgt ttgttcggca
    15301 cgaacgggat gtcttcaccg gtatgccaaa tcacggagtt ggtcgcggat ttgcgtgaag
    15361 aaccagtacc gaccacgtcg ccgacgtagg caacaggatg acctttggct ttgagttctt
    15421 ccaacaattt aatcgggccg acttcgcccg gtttgtcggg attgatgccg tcgcgcgggt
    15481 ttttcaacat cgccagcgcg tgcagcggaa tatcgggacg gctccacgcg tcgggcgcgg
    15541 gagagagatc gtccgtattg gtttcgccgt cgactttgaa gacggtaacg gtgatttttt
    15601 cgggaacttt ggcacgggaa gtgaaccatt cggcatccgc ccaagattgc aatacttcct
    15661 gcgcgtattt gttgcctttt tcggcttttt cctgaacgtc gtggaaggaa tcgaacatca
    15721 gaagtgtatg tttcaagcct ttggcggcaa tgggcgcgag tttgtcgtcg tccaagagtt
    15781 cgattaaggc gtggatattg taaccgccga gcattgtacc taaaagttcg gtcgcatatt
    15841 cgggggaaat cagcgggctg gatgcgctgc cttcggcaag ggctgccaag aatgaggctt
    15901 tgactttggc ggcatcgtcc acgccgggcg gcacgcggtg ggccagcaat tcgactaaaa
    15961 agtcgccttc gcctgcgggc gggtttttca gcagctcgac caaatcggcg gtttgcaggg
    16021 cggtcagagg aagggcggga atgccgaggg cggcgcgctc ggcggcggct ttacgatagg
    16081 cttctaacat ctctttgttc ctttttctgt ttttcttttg tccggttgca aatgatttgc
    16141 gttaaatatt gtaaacaata tttgaaccgc tatcatagac tagttttaac aaaaatggaa
    16201 ctgttatgac aggcaatgta atagggaacg gctatctgcc tgtgggaata tgataataaa
    16261 aacaaatgcc gtctgaagag aggttcagac ggcatttgtt taacgttttt cctgtttgcg
    16321 tatcagccat atgccgatca gggcaaagag ggcggtggga aggatgccgg cgaggaaagg
    16381 cggtacgccg tagagccggg cggtaaatcc gaagagccgt ccggcgaagt ggaacagcag
    16441 tccgaggcag atgccgccga agagtttcaa gcccatattg ccgtggcggg tggtttgcgg
    16501 ggtgaaggcg agggcgacga gcgccatcac ccaggcggcg acggggtaaa ccagtttgtg
    16561 ccacagggca atcgcgtaga tttgggtgtt ttgcctgttg ttttcgaggt ggctgatgta
    16621 ggcggtcagt tcgccgacgg acatttgatc gggtttgacg agcaacactt ccatgaggtt
    16681 gcgcttgacg gaaatcggca ggttttcttc ggctgcggag gaggtttcga ctttgtcttc
    16741 gccaagcgtg ctgcggcgga tgtttttcaa ctgccagctg ccgtcgtcgt ttaaaacggc
    16801 ggactcggct tccgttgcct gcaccagttc gtttttatcg ttgcgctccc aaattttgat
    16861 gcccagcagg gtatggtcgg gcagcatttc gcgtatgttg atgatgctgt tttgttcttt
    16921 gagccaaagg ccggtattgc cggtgctgat tttgccgttg atggcggcgg ctttgatgtt
    16981 ttcggctttt tggttcagcg cgggggcaat ccattcgccg agcgcggcgg tggcgagggc
    17041 gaaaatcagc ccgaactgcg acaggaccga taatagtttc cgggtgctta cgccgcctgc
    17101 cttgatgacg gtcagttcgc tgtcggcagc cagcctgccg agggaaagca gcccgcctat
    17161 cagggtggcg aggggcatca gttcgtaggt gcgggcgggc attttgaggg cggtgtagcc
    17221 cagcatttcc catatgccgt aactgccttt gccgaggttg ccggtttcgt acaggatttc
    17281 aaaaaagctg tacaaagcga ggaaggcgag gagggtgtaa acggtcatcg ccgtcatttg
    17341 gcggatgatg tagcgtgaaa tcaggttcat tttctgcctt tcggtgtcag gctttcggca
    17401 acggcccgcc aaaatggccg cgcgggcata ctgcggacgc gcaacagaat gagtgcaacg
    17461 gcaaacatga tgatgtgcat aggcagaagt ccgagccaga aatggatttt tccattttca
    17521 acggcttcaa aaagcagggt cagcccgttt tggtaaatta gaaacaaacc gatggcaatc
    17581 aagatattgt aggtgtgtcc gccgcgcggg ttgaaatagg aaagcggcac ggcgagcagg
    17641 cacagcagca aaacgctgac ggtcagcgag atgcgccaca tcaattccgc ctgatgttgc
    17701 ggattgctgc tgccgatcag ttgggcggtc ggaatggtac ggcggtgtga aacagggtcg
    17761 atgagtttgg gcgtggtgct gataatcagg ctgaggtgcc ggaaagaaac gcggttgtag
    17821 tcggctttgc cgggtgtacc gctgtaacgg tagccgtcgc gtaattcaag cgcgcgtttg
    17881 ttgttgttca gcgagaaatt gccttctttg gcgaagataa tgttgtcgtt gccgtttttg
    17941 tcctgttcgc gcaggaacag gtttttcatg atgccggatt cggtgtcgaa ggtttcgaca
    18001 aaataaaccc tgccgttgcg cttgcccaaa gtgttgaacc tgcctgcttc caccaaagac
    18061 aattcctgct tctgcttcaa tatttcggca tattcgcggc tgcgcagttc cgcccacggc
    18121 atcacccaaa gctgcatcac ggcaaccaaa acggcaaacg gcacggcaaa ctgcatgacc
    18181 gggcgtatcc actgtttcaa tgccaacccg caggagagcc agaccgacat ttcgctgtcg
    18241 cgccagtagc gggtcaacac ggtcaacgta ctgataaatg cggtcaacac cagcaaaagc
    18301 ggcgtcatac cgatgaccca gaagccgacc aatgccaaca cggcatcgat ggcgacacgc
    18361 ccgtcggcgg cacggccgag caggttgatt gcctgcgtgg agaccaatac cgccaagagg
    18421 acgacgaaaa tgccgacggc ggtaaaagag agttctttga tgaggtttct ttgataaatc
    18481 atagaatcgc ggtcaggggg cggtaagcgg ttcggcgcag gcggattgtc cgcgcaaggt
    18541 ttcagacggt gcttcaaatg gggtacaatc gtgccagccg tcttcagacg gtcttttgag
    18601 cgaaaggccg tccgaaaact accgacaacc gtctcaatca ggagaataaa cgtggaattt
    18661 agcacaaaaa ccgaaatctt gcaggaacag caggcaggcg cacagttatt tgtctgcacc
    18721 gaagaggcgc aattaaacca tccgaccgcc cttgcccttt tgtcttcgct tgaagaaggt
    18781 caaaattttg ccgacacaaa aatcccgaca ggcaacggtt tgcaggctgt tgccgtatgc
    18841 tgtctgaaaa gcaccggccg cgccgcattg aacaaggccg ccgccgaagc cgccaaatgg
    18901 gcgcaaaatc aggaaacggt caatgtggac atccatgcct tcgatgaagc gcaagccgcc
    18961 gccgtagccg aagcgtttgc gattgcgttc ggcaacgccg cctaccgttt cgaccgctac
    19021 aaaaaagaag ccaagcccgc caaatttgaa accgccgtgt tccacagcgc acacgaagcc
    19081 gccgttaaag aagccttgcg cgtcgccgaa gcgcaagttt acggacaaag cctctgccgc
    19141 gacttgggca acgccgcgcc caacgaatgc acgcccgaat ttttagcgcg caccgccaaa
    19201 gccgaagccg aaaaactggg cgcgcacgcc aaaatcatcg aaaaagacta catcaaagaa
    19261 aacatgggtt cgttttggtc ggtcgccaaa ggcagcgcgg aagcccccta tttggtcgaa
    19321 ctgagctatt tcggtgcagc cgacaaagaa gccgcgcctg tggtattggt cggcaaaggc
    19381 attaccttcg acaccggcgg catctccctc aagcccggcc tgaacatgga cgaaatgaag
    19441 tttgatatgt gcggcgcggc aaccgtcatc agcaccttct gcgccgccgt caaactgcaa
    19501 ctgccgatta acctgattgc cgtcgtcgcc acttgtgaaa atatgccttc cggcgcggca
    19561 aacaaaccgg gcgatgtcgt gaaaagtatg aaaggtctga ccatcgaagt gttgaacacc
    19621 gatgccgaag gccgtctgat tttgtgcgac gcgctcactt acgccgagca gttcaaaccc
    19681 aaagccgtca tcgacgtcgc caccctgacc ggtgcatgca tcgtcgcctt ggggcacgat
    19741 gtcagcggcg tgatgggcaa caatcaggat ttgatcgaca gcctgcttgc cgcttcctac
    19801 aacgtggacg acaaagcatg gcaactgccg ctctttgaga cctacaaaga ccaactcaaa
    19861 tccaactttg ccgacattcc aaacatcggc acgcccggcg cgggcacgat taccgccgca
    19921 acattcctat cctactttac cgaagactat ccatgggcac accttgacat cgcgggtacg
    19981 gcgtggaaat ccggtgcgga aaaaggtgcg actggccgtc ccgttccctt gctgctgaac
    20041 tatctgcgga atctttaatt ttgccacaat gccgtctgaa gcctttcaga cggcattatc
    20101 ctgccaaatg ttcaaacaat atgccgaaag ccacctttta cacgcacgtt gcccaagttc
    20161 cgattttcac ctgccgcctg attgcccgtg cgattcggga cggcggcagg atactggtgt
    20221 ggtccgattc gttcgggcag cttcaggaat tggacaaaat gctttggcaa tacgaggccg
    20281 agagtttcat tccgcacgaa atttgggaaa cggaagaagc catgccgtct gaaacatccg
    20341 tcctgcttgc ctgcggcggc aatctgcccc gaattcccga aggcatgacc gttttgaacc
    20401 tgtccgacgg tttttggaac accgctccgg tcttgcccgc gcgcgttttg gaaatcgtcg
    20461 gcaacagctt ggaagatctc gccgacgcgc gcgaacgctt taccgcctac cgccgaagcg
    20521 gttttgccat cgaacatcac ggcatggagg gcaaggcata aaatgccgtc tgaaatgccg
    20581 catttacaaa atttaaacag gcttgattct atttgattaa aatttcctta tcggttgaac
    20641 cccgccactt ggacatctgt ccctcggggc ggtagaatca aaacttattt tggaaggttc
    20701 aatcccttcc aaaacagggc aacacacgat tgacgcttta tgtgtcatcc tgtgtgttga
    20761 aacattcaaa ctcggctata atcccgtttt tccgacctta tcgacagcga agatccatca
    20821 tgaacaccat tttcaaaatc agcgcactga ccctttccgc cgctttggca ctttccgcct
    20881 gcggcaaaaa agaagccgcc cccgcatctg catccgaacc tgccgccgct tcttccgcgc
    20941 agggcgacac ctcttcgatc ggcagcacga tgcagcaggc aagctatgcg atgggcgtgg
    21001 acatcggacg ctccctgaag caaatgaagg aacagggcgc ggaaatcgat ttgaaagtct
    21061 ttaccgaagc catgcaggca gtgtatgacg gcaaagaaat caaaatgacc gaagagcagg
    21121 ctcaggaagt catgatgaaa ttccttcagg aacaacaggc taaagccgta gaaaaacaca
    21181 aggcggacgc gaaggccaat aaagaaaaag gcgaagcctt tctgaaagaa aatgccgcca
    21241 aagacggcgt gaagaccact gcttccggcc tgcaatacaa aatcaccaaa cagggtgaag
    21301 gcaaacagcc gaccaaagac gacatcgtta ccgtggaata cgaaggccgc ctgattgacg
    21361 gtacggtatt cgacagcagc aaagccaacg gcggcacggt caccttccct ttgagccaag
    21421 tgattccggg ttggaccgaa ggcgtacagc ttctgaaaga aggcggcgaa gccacgttct
    21481 acatcccgtc caaccttgcc taccgcgaac agggtgcggg cgacaaaatc ggcccgaacg
    21541 ccactttggt atttgatgtg aaactggtca aaatcggcgc acccgaaaac gcgcccgcca
    21601 agcagccggc tcaagtcgac atcaaaaaag taaattaagt ccgaatccat gcccgaaaca
    21661 ggttttcggg catttttacg gcaaatgccg tctgaaacca ccaaacagcg gttcagacgg
    21721 catccctttc aaaagcgtac cattatgaaa aacatcgtca tcctgatttc cggacgcggc
    21781 agcaatatgc aggcaatcgt caatgccgcc attcccaacg tccgcattgc cgccgtgttg
    21841 agcaacagcg aaacggctgc cggtttgcaa tgggcggccg aacgcggcat cccgaccgat
    21901 agcctgaatc ataaaaactt tgaatcacga cttgccttcg atacggccat gatggaaaaa
    21961 atcgacgcat atcaacccga tttggtggtt ttggcaggtt ttatgcggat tctgaccccc
    22021 gagttttgcg cccattacga aggcaggctg atgaacatcc atccgtccat cctgccttca
    22081 tttactgggc ttcatacgca cgaacgcgct ttggaagcgg gttgccgcgt tgcaggctgt
    22141 acgattcact ttgttacggc cgagctggat tgcggcccga ttgtatcgca agggattgtg
    22201 ccgatacttg atggtgatac ggcagacgat attgccgccc gggttttggc tgtcgaacac
    22261 aaactctatc cgaaagccgt tgccgatttt gccgccggcc gcctgattat cgagggaaac
    22321 cgcgtcagaa attcggaaaa cgccgatgcc gcccgtttcc tgacggcgta aaccgggcgg
    22381 gagcaaatga tgaagacttt taaaaatata ttttccgccg ccattttgtc cgccgccctg
    22441 ccgtgcgcgt atgcggcagg gctgccccaa tccgccgtgc tgcactattc cggcagctac
    22501 ggcattcccg ccacgatgac atttgaacgc agcggcaatg cttacaaaat cgtttcgacg
    22561 attaaagtgc cgctatacaa tatccgtttc gagtccggcg gtacggttgt cggcaatacc
    22621 ctgcacccta cctactatag agacatacgc aggggcaaac tgtatgcgga agccaaattc
    22681 gccgacggca gcgtaaccta cggcaaagcg ggcgagagca aaaccgagca aagccccaag
    22741 gctatggatt tgttcacgct tgcctggcag ttggcggcaa atgacgcgaa actccccccg
    22801 gggctgaaaa tcaccaacgg caaaaaactt tattccgtcg gcggtttgaa taaggcgggt
    22861 acaggaaaat acagcatagg cggcgtggaa accgaagtcg tcaaatatcg ggtgtggcgc
    22921 ggcgacgata cggtaatgta tttcttcgca ccgtccctga acaatattcc ggcacaaatc
    22981 ggctataccg acgacggcaa aacctatacg ctgaaactca aatcggtgca gatcaacggc
    23041 cgggcagcca aaccgtaaat cggttttcaa gtgttttttt gccgttttgt ccatatttct
    23101 gcataagccg cttgaaattg tttacaataa cgccatatgc aaagcggttt taacgctatt
    23161 ttcaggaatg acaccatgca ggttacatca aaatggatag acggaatgtg ctttgtcggc
    23221 acgacggaag gcgggcacag cgtcgttatg gagggttcgg cggcagaagg tgcggccaag
    23281 cgcgggccca gccctttgga aatgctgctg ttgggcgtgg cgggctgttc gagcatcgat
    23341 gtggtgatga ttgccgaaaa acagcgtcag aaagtgactg actgccgtgc gacggttacg
    23401 gcgaaacggg cggacgatgc gccgcgcgtg tttaccgaaa tccacatcca tttcaaagta
    23461 ttcgggcatg atttgaaaga atcggccatt gagcgcgccg ttcagatgtc tgccgaaaaa
    23521 tactgttcgg cttcgattat gttgggcaaa gcggcaaaga ttacccacag ttttgaaatt
    23581 gccggggcag ataaataggc atcgggcggc attatgggga aacggctgat accgtctgaa
    23641 gggaaaggtg cggcaggcaa tccggaggcg cataaaaaag cagatatatt cggactgcac
    23701 ctcccgaata tatctgcctg ctgtttcctc tttattcagc ctttataata cttggacttg
    23761 tcggggtatt gtgcagactt gattccggat tgtcaacaat tttcggtcaa attttaaatg
    23821 ccgcgtttta aaatgatacc cgcctgcttc tgcgggcggg cgggaggcga gaatcccgtt
    23881 attttaagcc atatattaat ttattgaatt atagtggatt aacaaaaacc agtacggcgt
    23941 tgcctcgcct tggctcaaag agaacgattc tctaaggtgc tgaagcacca agtgaatcgg
    24001 ttccgtacta tctgtactgt ctgcggcttc gtcgtcttgt cctgattttt gttaatccac
    24061 tataa
//
LOCUS       DAXISH010000027        23908 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.027, whole genome shotgun sequence.
ACCESSION   DAXISH010000027 DAXISH010000000
VERSION     DAXISH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 23908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23908
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.027"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(197..1366)
                     /gene="metK"
                     /locus_tag="ACFOV4_001084"
     CDS             complement(197..1366)
                     /gene="metK"
                     /locus_tag="ACFOV4_001084"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFC7619108.1"
                     /translation="MSEYLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAET
                     LVNTGLCVLAGEITTTAQVDYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPD
                     IAQGVNEGEGIDLNQGAGDQGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGLL
                     PWLRPDAKAQLTVVYDSESGKVKRIDTVVLSTQHDPEIGYEELKNAVIEQIIKPVLPS
                     ELLTDETKYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVD
                     RSAAYACRYVAKNIVAAGLATQCQIQVSYAIGVAEPTSISIDTFGTGKISEEKLITLV
                     REHFDLRPKGIVQMLDLLRPIYSKSAAYGHFGREEPEFTWERTDKAAALRAAAGL"
     regulatory      complement(1549..1659)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01725"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM-I-IV-variant riboswitch; SAM riboswitches
                     modulate the expression of downstream genes in response to
                     levels of S-adenosylmethionine; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01725"
     gene            1712..2608
                     /locus_tag="ACFOV4_001085"
     CDS             1712..2608
                     /locus_tag="ACFOV4_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFC7619109.1"
                     /translation="MFRLQFGLFPPLRTAMHILLTALLKCLSLLPLSCLHTLGNRLGH
                     LAFYLLKEDRARIVANMRQAGMNPDPKTVKAVFAETAKGGLELAPAFFRKPEDIETMF
                     KAVHGWEHVQQALDKHEGLLFITPHIGSYDLGGRYISQQLPFPLTAMYKPPKIKAIDK
                     IMQAGRVRGKGKTAPTSIQGVKQIIKALRSGEATIVLPDHVPSPQEGGEGVWVDFFGK
                     PAYTMTLAAKLAHVKGVKTLFFCCERLPGGQGFDLHIRPVQGELNGDKAHDAAVFNRN
                     AEYWIRRFPTQYLFMYNRYKMP"
     gene            complement(2652..3716)
                     /gene="tsaD"
                     /locus_tag="ACFOV4_001086"
     CDS             complement(2652..3716)
                     /gene="tsaD"
                     /locus_tag="ACFOV4_001086"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFC7619110.1"
                     /translation="MLVLGIESSCDETGVALYDTERGLRAHCLHTQMAMHAEYGGVVP
                     ELASRDHIRRLVPLTEGCLAQAGASYGDIDAVAFTQGPGLGGALLAGSSYANALALAL
                     GKPVIPIHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDD
                     AAGEAFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAV
                     LTAVEKVRAENGADDIPEQTRNDICRAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGV
                     GANRKLRETFGSMTVQIPTPTGKPKHPSEKVSVFFPPTAYCTDNGAMIAFAGAMHLGK
                     GREVGAFNVRPRWPLSEIVK"
     gene            3723..3848
                     /locus_tag="ACFOV4_001087"
     CDS             3723..3848
                     /locus_tag="ACFOV4_001087"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619111.1"
                     /translation="MPLKTEKRILADFGTTAVSQKRNMPSEDRSDGIVAPYQSVP"
     gene            complement(3833..5020)
                     /gene="ccsB"
                     /locus_tag="ACFOV4_001088"
     CDS             complement(3833..5020)
                     /gene="ccsB"
                     /locus_tag="ACFOV4_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome biogenesis protein CcsB"
                     /protein_id="HFC7619112.1"
                     /translation="MTEHYKTLPEHELLIQKSLISNLNLWDWVFAVLVFAATVFVQTR
                     SGMHMDIYETVMLWASAGIAVFLGWFFKPMRWFVPLSVLLAYAAVGLYGGNIKSAEIF
                     LLRYFLSSQSAIMWQCAFVFFALFAYISGAVLASVKNVPTNTLLGMGTVFAWVSAVAG
                     FTGLLVRWHESYLLRPDAGHIPVSNLYEVFILFLVITALMYLYYEGKFAIQKLGGFVF
                     GFMAVVVGFVLWYSVSREAHTIQPLIPALQSWWMKIHVPANFIGYGAFCISAMLGIAE
                     LVSLRTEGKGGKSWLPQSVLIEEVMYKAIAVGFLFFTIATILGALWAADAWGRYWSWD
                     PKETWAFIVWLNYAVWLHLRLVAGWRGKVLAWWAIIGLFVTAFAFIGVNMFLSGLHSY
                     GTL"
     gene            complement(5013..6965)
                     /locus_tag="ACFOV4_001089"
     CDS             complement(5013..6965)
                     /locus_tag="ACFOV4_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein ResB"
                     /protein_id="HFC7619113.1"
                     /translation="MRFAVALLSLLGIASVIGTVLQQNQPQTDYLVKFGSFWAQIFGF
                     LGLYDVYASAWFVVIMMFLVVSTSLCLIRNVPPFWREMKSFREKVKEKSLAAMRHSSL
                     LDVKIAPEVAKRYLEVQGFQGKTINREDGSVLIAAKKGTMNKWGYIFAHVALIVICLG
                     GLIDSNLLLKLGMLTGRIVPDNQAVYAKDFKPESILGASNLSFRGNVNISEGQSADVV
                     FLNADNGILVQDLPFEVKLKKFHIDFYNTGMPRDFASDIEVTDKATGEKLERTIRVNH
                     PLTLHGITIYQASFADGGSDLTFKAWNLGDASREPVVLKATSIHQFPLEIGKHKYRLE
                     FDQFTSMNVEDMSEGAEREKSLKSTLNDVRAVTQEGKKYTNIGPSIVYRIRDAAGQAV
                     EYKNYMLPVLQEQDYFWITGTRSGLQQQYRWLRIPLDKQLKADTFMALREFLKDGEGR
                     KRLVADATKDAPAEIREQFMLAAENTLNIFAQKGYLGLDEFITSNIPKEQQDKMQGYF
                     YEMLYGVMNAALDETIRRYGLPEWQQDEARNRFLLHSMDAYTGLTEYPAPMLLQLDGF
                     SEVRSSGLQMTRSPGALLVYLGSVLLVLGTVLMFYVREKRAWVLFSDGKIRFAMSSAR
                     SERDLQKEFPKHVESLQRLGKDLNHD"
     gene            complement(7242..7865)
                     /locus_tag="ACFOV4_001090"
     CDS             complement(7242..7865)
                     /locus_tag="ACFOV4_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HFC7619114.1"
                     /translation="MKRLTLLAFVLAAGAVSASPKADVEKGKQVAATVCAACHAADGN
                     SGIAMYPRLAAQHTAYIYHQTIGIRDGKRTHGSAAVMKPVVMNLSDQDILNVSAFYAK
                     QQPKSGEANPKENPELGAKIYRGGLSDKKVPACMSCHGPSGAGMPGGGSEIQAYPRLG
                     GQHQAYIVEQMNAYKSGQRKNTIMEDIANRMSEEDLKAVANFIQGLR"
     gene            8071..8700
                     /gene="yihA"
                     /locus_tag="ACFOV4_001091"
     CDS             8071..8700
                     /gene="yihA"
                     /locus_tag="ACFOV4_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFC7619115.1"
                     /translation="MNLFQNAKFFTTVNHLKDLPDTPLEIAFVGRSNAGKSSAINTLT
                     NHVRLAYVSKTPGRTQHINFFELQNGNFMVDLPGYGYAQVPEAVRAHWVNLLGDYLQQ
                     RKQLIGLVLIMDARHPLKELDIRMLDFFHTTGRPVHILLSKADKLSKNEQIKTLSQVK
                     KLLKPYSDRQNISVQLFSSLKKQGIDEANRTVGSWFDAADAAASSPEEN"
     gene            complement(8821..11217)
                     /locus_tag="ACFOV4_001092"
     CDS             complement(8821..11217)
                     /locus_tag="ACFOV4_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HFC7619116.1"
                     /translation="MIKKILTTCFGLVFGFCVFGVGLVAIAILVTYPKLPSLDSLQHY
                     QPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWG
                     VARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDK
                     ILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPE
                     RAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQELYE
                     KYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSEDVE
                     ETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEK
                     MGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFN
                     RAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRY
                     SGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGETT
                     PLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIM
                     YKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPK
                     SMGRVGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLT
                     LDNSGIAPQPSRRAKEDDGGAAEGGRQAADDEVRQDMQETPVLPSNTGSKQQQLDSLF
                     "
     gene            11369..12484
                     /gene="pilM"
                     /locus_tag="ACFOV4_001093"
     CDS             11369..12484
                     /gene="pilM"
                     /locus_tag="ACFOV4_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="HFC7619117.1"
                     /translation="MRLFKSLKNPKKTDAKLPKKSSGLNNRAAIGIDIDQHSIKMVQL
                     SGRSLNQIQLEKYVIAKLPKNIIQGNKVQNYDQLVTYLQQAYAKLGTSCKNIIASVPQ
                     NLATIEQLTYTDKDAELDLQGFVESSISEVSSISLEEANYDYQVLSQSAAGEAVLAVA
                     SRKDEIEPLIDAFNAAGMKLSALDVDIFGQYNAYALWINHFAPELAAEKVAIFGVYAA
                     QTYALVIQDGKLLYKQETSVSEEQLNQLIQRTYQVTEEKAEEIINSPQKPSDYQESVA
                     NYFNQQITQEIQRVLQFYYTTQTADDMTDIKHILLTGEAARQEGIAQTVASQTNADVQ
                     CVHPARYFADNLKTDKQQFELDAPTLTRAFGLAVRGL"
     gene            12487..13086
                     /locus_tag="ACFOV4_001094"
     CDS             12487..13086
                     /locus_tag="ACFOV4_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HFC7619118.1"
                     /translation="MNNLIKINLLPYREEMNKRKQQQFKTLMYGAVLTGVAAVAATYL
                     FIDNMINNQSERNTLLETSIAHLDTELSEIQKLKQEKDAFLIKKNKIEELQLKRLQAA
                     KILDSLNEAVPGSTYLTSLDAVTADSYRLSGRTSSDNRVAAMMRAMPNTGIFKQPELL
                     SIKKNNSHQEFTLQATLQPIVKAAESKENPASGNAQEAN"
     gene            13087..13734
                     /locus_tag="ACFOV4_001095"
     CDS             13087..13734
                     /locus_tag="ACFOV4_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HFC7619119.1"
                     /translation="MASKSSKTNLDLNNLHLLNLPARLFIALLAVAAVLGLGYAGLFK
                     SQMESLEEYEAKETELKNTYKQKSIDAASLNNLRDELASIRSAFDIMLKQLPTDAEIP
                     NLVQELHQAGSSNGLRLDSVMPQPPVDDGPIKRLPYSISITGNYEQISQFTRDVGSLS
                     RIITLESLKIAQSPENGGNPDGKSSILNLSAIATTYQAKSVEELAAEAAQNAEQK"
     gene            13752..14297
                     /locus_tag="ACFOV4_001096"
     CDS             13752..14297
                     /locus_tag="ACFOV4_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilP"
                     /protein_id="HFC7619120.1"
                     /translation="MKHYALLISFLALSACSQGSEDLNEWMAQTRREAKAEIIPFQAP
                     TLPVAPVYSPPQLTGPNAFDFRRMETDKKGENAPDTKRIKETLEKFSLENMRYVGILK
                     SGQKVSGFIEAEGYVYTVGVGNYLGQNYGRIESITDDSIVLNELIEDSTGNWVSRKAE
                     LLLNSSDKNTEQAAAPAAEQN"
     gene            14316..16601
                     /gene="pilQ"
                     /locus_tag="ACFOV4_001097"
     CDS             14316..16601
                     /gene="pilQ"
                     /locus_tag="ACFOV4_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus secretin PilQ"
                     /protein_id="HFC7619121.1"
                     /translation="MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKV
                     SFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLV
                     LNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
                     SVSKPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQTAAPAKQQAATPAKQT
                     NIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKT
                     PVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKT
                     FTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQ
                     ARNLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRS
                     ILRLDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQV
                     MIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINL
                     PITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIP
                     FTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTIL
                     CISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDR
                     RELLIFITPRIMGTAGNSLRY"
     gene            17779..18291
                     /locus_tag="ACFOV4_001098"
     CDS             17779..18291
                     /locus_tag="ACFOV4_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFC7619122.1"
                     /translation="MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAVAA
                     GVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLSTGGGAVLKEENRALIRKSGTVV
                     YLHAPPETLLERTRCDNSRPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRET
                     VQTLLKRLSR"
     gene            18371..19450
                     /gene="aroB"
                     /locus_tag="ACFOV4_001099"
     CDS             18371..19450
                     /gene="aroB"
                     /locus_tag="ACFOV4_001099"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFC7619123.1"
                     /translation="MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIIANET
                     VAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIAL
                     GGGVIGDMVGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQP
                     QAVLADLDTLHTLPVRELSAGMAEVIKYGALGDIGFFEWLEQNISGLMTLDREKLAQA
                     VYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAIETEMGYGTWLHGEAIAAGCVLAA
                     RLSEQLGKTSAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSHDKKVSGGIMRFIGL
                     NRLGEANITEITDTDILRRTLQPYL"
     gene            20417..21259
                     /locus_tag="ACFOV4_001100"
     CDS             20417..21259
                     /locus_tag="ACFOV4_001100"
                     /EC_number="2.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HFC7619124.1"
                     /translation="MCQLLGMNCNTPTDIMFSFEGFRRRGGITDHHADGFGIGFFEGK
                     GVRLFHDDKPSANSPVADLVRAYQIKSENVVAHIRKASQGQTSLANTHPFMREMWGGY
                     WLFAHNGHLIDFFPEQGEFFHPVGTTDSERAFCHILNRLRTRFAARPDDDTLFDAIAG
                     LTHEIRKFGLFNFMLSDGIALFAHASTLLHYIVRQAPFGKARLLDDDVMVDFAEVTTP
                     NDRVAVIATLPLTRDESWSQLAVNELVMFREGNIVRHDRPENPVYMSAEEGLEIARAA
                     GVSV"
     gene            21288..21752
                     /locus_tag="ACFOV4_001101"
     CDS             21288..21752
                     /locus_tag="ACFOV4_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFC7619125.1"
                     /translation="MKCPFCAHPDTRVADSRLMEERNAVRRRRHCPNCGKRFGTLETA
                     ELKMPAVIGTDKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHRLYTSGQRD
                     IPSTELADMVLKELLEHNTEAAVRFAALHKRFDNPSDFASWLAQAVKTDRKA"
     gene            21785..22894
                     /gene="ribD"
                     /locus_tag="ACFOV4_001102"
     CDS             21785..22894
                     /gene="ribD"
                     /locus_tag="ACFOV4_001102"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HFC7619126.1"
                     /translation="MFSDTDISMMEIALRLAALGRFSTSPNPRVGCVIAHGSQIVGQG
                     FHVKAGEPHAEVHALHQAGEMAKGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAA
                     MRDPNPLVAGKGLALLEAAGIKTECGLLEHQARKLNRGFLSRIERRRPFVRLKCAVSL
                     DGKTALSDGSSFWITGEDARADVQVLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQP
                     ARIVLDSRLRLPPNSHLVTDGQSPTYIATLERNEDRLHPYREHAHVRILMPSETADSK
                     IDLHHLMRLLADEGFGEIMVEAGSELTSAFLAENLADEIVLYRSPKILGSGKDLFSLL
                     ENRAALSAPPLWTPVSSEILGHDIKTVFRKNGNAF"
     gene            23089..>23908
                     /locus_tag="ACFOV4_001103"
     CDS             23089..>23908
                     /locus_tag="ACFOV4_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFC7619127.1"
                     /translation="MDTKEILGYAAGSIGSAVLAVIILPLLSWYFPADDIGRIVLMQT
                     AAGLTVSVLCLGLDQAYVREYYAAADKDTLFKTLFLPPLLSAAAIAALLLSRPSLPSE
                     ILFSLDDAAAGIGLVLFELSFLPIRFLLLVLRMEGRALAFSSAQLVSKLAILLLLPLT
                     VGLLHFPANTAVLTAVYALANLAAAAFLLFQNRCRLKAVRRAPFSSAVLHRGLRYGIP
                     IALSSIAYWGLASADRLFLKKYAGLEQLGVYSMGISFGGAALLFQSIFSTVWTPY"
BASE COUNT         6162 a         6992 c         5557 g         5197 t
ORIGIN      
        1 aatttaaacc agtacagcgt tgcctcgcct tagctcaaag agaacgattc tctaaggtgc
       61 tgaagcacca agtaaatcgg ttccgtacta tctgtactgt ctgcggcttc gtcgccttgt
      121 cctgattttt gttaatccac tatataaaaa tgccgtctga actgttcaga cggcattttt
      181 gattttcaaa ccggaattac agccccgctg ccgccctcaa tgcagcagct ttgtcggtgc
      241 gctcccaagt gaactcaggt tcttcgcggc cgaaatgtcc gtaagcggcg gatttactgt
      301 aaatcgggcg caagagatcg agcatttgga cgatgccttt ggggcgcagg tcgaaatgtt
      361 cgcgaactaa ggtaatcagt ttttcctcgc tgattttgcc tgtgccgaaa gtgtcgatgg
      421 aaatcgaagt cggttcggca acgccgatgg cgtaggaaac ttggatttgg cattgggttg
      481 ccaaaccggc ggcgacgatg tttttcgcaa cgtagcggca ggcgtaagcg gcggaacgat
      541 ccactttgga cgggtctttg ccggagaacg caccgccgcc gtgcggagcc gcgccgccgt
      601 aggtatcaac gatgatttta cggccggtca aaccgcagtc gccttgcggg ccgccgatga
      661 cgaagcggcc ggtcgggttg atcaggtatt tggtttcgtc ggtcagcagt tcagacggca
      721 ggacgggctt gataatctgc tcaatgacgg cgtttttcaa ctcttcataa ccgatttccg
      781 ggtcgtgttg cgtagagagg acgacggtat caatgcgttt tactttgccg gattcgctat
      841 cgtaaaccac ggtcagttgg gcttttgcgt cgggacgcag ccaaggcagg aggccgtctt
      901 tgcgtaattc gctttgacgc tgcatcaggc ggtggctgta atagatggca aacggcatca
      961 gggtcggggt ttcgtcgcag gcatagccga acatcaaacc ttggtcgcca gcgccttggt
     1021 tcaagtcaat gccttcgcct tcgttcacgc cttgggcgat gtccggagat tgctggtcgt
     1081 agtacacgcc gaccgcgcag ccgttggcat caaagcccag ctcggaggag ttgtagccga
     1141 tgcgtttgat ggtttcgcgt gcgactttga tgtagtccac ttgggcggtg gtggtgattt
     1201 cgcctgccaa tacgcacaag cctgtgttga ccaaagtttc tgcggcgaca cgcgctttgg
     1261 ggtcttgcgc caagatggca tccaaaatcg cgtcggatac ttggtcggca actttgtccg
     1321 gatggccttc ggataccgat tcggaagtaa acagatattc gctcattgag attttccttg
     1381 aaaaacaaac catcttcttc agacggcatg ttgtatgaac ataatgtcga cagcgggaaa
     1441 tatagcaaaa tttccctatt cataccattc agttgagaaa tattcccatt tgaatggcac
     1501 tttggaatct ctgcccgtac gtttcttaca ggcaaaaaaa ttcccgcatc aagcgggttt
     1561 ggattgctct ggtgagccac atcggctttt caaccgtcca ccttactttt ccttttgaaa
     1621 agcaggttgg catggaattc ccaactctta atgcagcgcg gatggtagca gaaaagcctt
     1681 tccgccgcaa tacttccctt tttcagacgg catgtttcgt ttacaattcg ggctgtttcc
     1741 ccctttgcga accgccatgc acatcctgtt gaccgccctg ctcaaatgcc tctccctgct
     1801 gccactttcc tgtctgcaca cgctgggaaa ccggctcgga catctggcgt tttacctttt
     1861 aaaggaagac cgcgcgcgca tcgtcgccaa tatgcgtcag gcaggcatga atcccgaccc
     1921 caaaacagtc aaagccgttt ttgcggaaac ggcaaaaggc ggtttggaac ttgcccccgc
     1981 gtttttcaga aaaccggaag acatagaaac aatgttcaaa gcggtacacg gctgggaaca
     2041 tgtgcagcag gctttggaca aacacgaagg gctgctattc atcacgccgc acatcggcag
     2101 ctacgatttg ggcggacgct acatcagcca gcagcttccg ttcccgctga ccgccatgta
     2161 caaaccgccg aaaatcaaag cgatagacaa aatcatgcag gcgggcaggg ttcgcggcaa
     2221 aggaaaaacc gcgcctacca gcatacaagg ggtcaaacaa atcatcaaag ccctgcgttc
     2281 gggcgaagca accatcgtcc tgcccgacca cgtcccctcc cctcaagaag gcggggaagg
     2341 cgtatgggtg gatttcttcg gcaaacctgc ctataccatg acgctggcgg caaaattggc
     2401 acacgtcaaa ggcgtgaaaa ccctgttttt ctgctgcgaa cgcctgcctg gcggacaagg
     2461 tttcgatttg cacatccgcc ccgtccaagg ggaattgaac ggcgacaaag cccatgatgc
     2521 cgccgtgttc aaccgcaatg ccgaatattg gatacgccgt tttccgacgc agtatctgtt
     2581 tatgtacaac cgctacaaaa tgccgtaacg aaaataaaaa tgccgtctga acaatttcag
     2641 acggcatttt gtcatttgac gatttccgac agcggccagc gcggacggac attgaacgca
     2701 ccgacctccc tgcccttgcc caggtgcatc gcaccggcaa aggcaatcat ggcaccgttg
     2761 tccgtgcagt atgccgtcgg cgggaaaaac acgctgactt tttcggacgg atgtttcggc
     2821 ttgcctgttg gggtcgggat ttgcaccgtc atgctgccga aagtttcacg gagtttgcgg
     2881 tttgcaccga ccccgccggc gaccactacg gttctgaacc ctgtctgcaa cagggctttt
     2941 ttcactttcg ccgccaacac atcgactacc gcatcttgaa acgcacggca gatgtcgttg
     3001 cgtgtctgct caggaatgtc atccgccccg ttttccgcgc gcactttctc gacggcagtc
     3061 aaaacagcgg ttttcaaacc tgaaaaactc atctgcaaat cgtcggaatg aatcatcggg
     3121 cgcggaaaaa caaacgcttc gggcctgccc gattccgcaa gttccgacag tttcgcaccg
     3181 cccggatacg gcaagcccag cagtttcgcc gttttgtcga atgcctcgcc cgccgcatca
     3241 tcgacgctct cgcccaaaag cgcgtagtcg cctatgcccc tgaccgccat aatctgcgta
     3301 tgcccgcccg aaaccagcag cgcgacaaaa ggaaagtcgg gtttttcctc cgccaacagc
     3361 ggcgacagca gatgtccttc caaatgatgg atggggatga cgggcttgcc caatgccaaa
     3421 gccagtgcat tggcgtagct cgaacccgcc agcagcgcac cgcccagacc gggtccctgc
     3481 gtaaaggcaa ccgcgtcaat gtcgccatac gatgcacccg cctgcgccaa acagccttcc
     3541 gtcaacggaa caaggcggcg gatatggtcg cggcttgcca attccggcac aaccccaccg
     3601 tattcggcgt gcattgccat ttgagtgtgc aggcagtgcg cccgcaatcc tcgttccgta
     3661 tcgtaaagcg caacgccggt ttcgtcgcaa gaagactcga ttcctaatac caacatggtc
     3721 tgatgccgtt aaaaactgaa aaacgtattt tagcggattt cggcacgact gccgtatccc
     3781 aaaaacggaa catgccgtct gaagaccgtt cagacggcat cgtcgcaccg tatcaaagcg
     3841 ttccgtaaga atgcagcccg ctcaaaaaca tattcacgcc gataaaggca aatgcggtta
     3901 cgaacaaacc gataatcgcc caccacgcca gcactttgcc gcgccaaccg gcaaccagcc
     3961 gcaagtgcag ccaaacggcg taattgagcc agacgatgaa cgcccacgtc tctttcgggt
     4021 cccaactcca atagcgtccc caagcatccg ccgcccacag cgcacccaaa atggtggcaa
     4081 tggtaaagaa cagaaagccg acggcaatcg ccttatacat aacttcctca atcaacacgg
     4141 attgcggcag ccacgatttc ccgccttttc cttccgtacg cagggaaacc agttcggcaa
     4201 taccgagcat cgcggaaatg caaaacgcgc cgtaaccgat aaagtttgcc ggaacgtgga
     4261 ttttcatcca ccaagattgc aatgccggaa tcagcggctg gatggtatgc gcctcgcggg
     4321 acacgctgta ccacaagaca aatccaacca cgaccgccat aaagccgaac acgaagccgc
     4381 ccaatttctg tatggcgaac ttaccttcat aataaagata catcagcgcg gtaatcacca
     4441 aaaacaggat gaacacttca tacaggttgg aaaccggaat atgccccgca tcgggacgga
     4501 gcagatagct ttcgtgccaa cgtaccagca gaccggtaaa gcctgctacg gcagacaccc
     4561 atgcaaacac ggttcccata cccaacagcg tgttggtcgg cacatttttt acgcttgcca
     4621 aaaccgcgcc cgaaatatag gcgaacaggg cgaagaagac aaaggcgcac tgccacataa
     4681 tcgccgactg gctgctgagg aaataccgca acaggaaaat ctctgccgat ttgatgttgc
     4741 cgccatacaa accgacggcg gcataggcaa gcaatacgct taaaggaaca aaccagcgca
     4801 tcggcttgaa aaaccagccc aaaaatacgg caataccggc actcgcccac aacatgaccg
     4861 tttcgtaaat gtccatatgc ataccggaac gggtctgtac gaaaaccgta gccgcaaaaa
     4921 ccagcacggc aaatacccaa tcccaaagat tcagattgct gatcaaagac ttctgaatca
     4981 gcagctcgtg ttccggaagg gttttatagt gttcagtcat gattcaagtc cttgccgagc
     5041 cgttgcagac tctcgacgtg ttttggaaat tccttctgca aatcccgttc gctgcgggcc
     5101 gaagacatgg caaaacggat tttgccgtct gaaaacaata cccacgcccg tttttcgcgc
     5161 acataaaaca tcaataccgt acccaatacc aacagcaccg agccgagata gaccaaaagc
     5221 gcacccgggg aacgggtcat ctgcaaaccc gacgaacgca cctcggaaaa cccatcaagt
     5281 tgcagcagca taggcgcggg atattcggtc aaacccgtgt acgcatccat actgtgcagc
     5341 aggaaacggt tccgcgcttc atcctgctgc cattcgggca agccgtaccg gcgtatggtt
     5401 tcatccaaag cagcgttcat cacgccgtaa agcatttcgt agaaataacc ctgcatctta
     5461 tcctgctgct ctttcggaat attggacgta ataaattcgt ccaatcccaa atagcctttt
     5521 tgtgcaaaga tgttcagcgt gttttccgca gccagcatga attgttcgcg gatttcggca
     5581 ggtgcgtctt tggttgcgtc ggcaaccaga cgtttgcgcc cttccccatc tttcaaaaac
     5641 tcgcgcaatg ccataaaggt gtccgctttc aactgcttgt ccaaggggat acgcagccag
     5701 cggtattgct gctgcaagcc gctgcgcgtg ccggtaatcc aaaaataatc ctgttcctgc
     5761 aaaaccggca gcatatagtt tttatattcg accgcctgcc ctgccgcatc acggatacgg
     5821 taaacaatgg aagggccgat attggtgtat tttttacctt cctgagtaac ggcgcggaca
     5881 tcgttcagcg tggatttcag gcttttttcc cgttccgcgc cctcgctcat gtcctccaca
     5941 ttcatagaag tgaactgatc gaactcaaga cgatatttgt gtttgccaat ttccaacgga
     6001 aactggtgta tggatgttgc cttcaacacg acaggctcgc gcgaagcatc acccaaattc
     6061 cacgccttga atgtcaaatc cgaaccgccg tcggcaaaac tcgcctgata aatcgtgatg
     6121 ccgtgcaagg tcaaaggatg gttcacgcgg atggtgcgct cgagtttctc accggttgcc
     6181 ttatccgtta cttcaatatc actggcaaaa tcgcgcggca tacccgtatt gtaaaaatcg
     6241 atatggaatt ttttcagttt gacttcaaaa ggcaagtcct gaaccaatat cccgttgtcg
     6301 gcattcagga aaaccacatc cgcactctgc ccctcggaaa tattgacgtt gcccctaaat
     6361 gagagattgg acgcacccaa aatactttcg ggcttgaaat ccttggcata aaccgcctga
     6421 ttgtccggaa caatccgacc ggtcagcata cccagtttca acagcaggtt actgtctatc
     6481 aacccgccca ggcaaatgac aatcaaagca acatgggcaa agatatagcc ccatttgttc
     6541 attgtgcctt ttttggcggc aatcagaacc gacccgtctt cacggttaat ggtttttccc
     6601 tgaaaacctt gtacttccag ataacgtttg gcaacctcgg gcgcaatttt tacatccaac
     6661 agcgaagaat ggcgcatcgc cgccagagat ttttctttaa ccttttcccg aaaagacttc
     6721 atttcgcgcc agaacggcgg cacattgcga atcaggcaca aactggtaga aaccaccaaa
     6781 aacatcatga taacgacaaa ccatgccgaa gcatagacgt catacagtcc cagaaaacca
     6841 aaaatctgcg cccaaaacga tccgaatttg accaaataat ccgtctgcgg ctggttttgc
     6901 tgcaacaccg taccgataac cgatgcaata cccagcagac tgagcaaagc gactgcaaag
     6961 cgcatggagc tgaaaaaagc gaaccacgga cgggaaagaa gtgggggaga tctacgggat
     7021 ttactcattg tgtgtttatt ccgccatcag gaatatggga aagcagaatt gggcaaacag
     7081 aaaacaacgt cccgattcta ctgtcttgat gctttttatt tcaagacaat gaagacagcc
     7141 tgcatcgatt ccaacggttg cgattgaaaa aacttatcgc agaattgcct gaagccgtct
     7201 gaaaactttt cagacggcct ctaaaacaga ctattgcgga attaacgcaa accttggata
     7261 aagttggcga ccgctttcaa atcttcttca gacatacggt ttgcaatatc ttccatgatg
     7321 gtatttttac gctgaccgga cttgtaggca ttcatctgtt caacaatata tgcctgatgc
     7381 tgaccgccca aacgcggata agcctgaatt tcgcttccgc ctcccggcat acccgcaccg
     7441 ctcggaccgt ggcaggacat acacgccggc acttttttat cgctcaaacc gccgcgatag
     7501 attttcgcac ccaattcggg attttcctta ggattggctt caccggattt gggctgctgt
     7561 ttggcataga atgcggatac gttcaaaata tcctgatcgc tcaaattcat taccaccggt
     7621 ttcatcacag ctgccgaacc gtgggtgcgt ttaccgtcgc ggatgccgat agtttgatga
     7681 tagatgtaag cagtatgctg tgccgccaaa cgcggataca tcgcaatgcc gctgttaccg
     7741 tctgctgcat ggcaagccgc acaaaccgtt gcggcaacct gtttgccttt ttccacgtct
     7801 gctttgggag aggcggaaac cgcaccggca gccaaaacaa aggccaataa agtcaatcgt
     7861 ttcatggagt gctcctgatt acagcattgg ataacgcaac aatgctcttt ttatattcaa
     7921 atacgggatt tttgacccga ttaaaaccga tgattctgta aacgtgttat tctatactaa
     7981 atttacatta aattaccact gtgtttcaca taaaaccaac cgcatatttt tgctgtcgga
     8041 caaacggcgg cggaaaacaa ggatatgccc atgaaccttt ttcaaaacgc caaattcttc
     8101 acgacggtca accaccttaa agacctgccc gacacccctc tcgaaattgc ctttgtcggc
     8161 aggagcaatg ccggaaaatc cagtgccatc aataccctga ccaaccatgt ccgtcttgcc
     8221 tacgtttcaa aaacacccgg acggacgcag catatcaact tcttcgagct gcagaacggc
     8281 aattttatgg tcgatttgcc cggctacggt tatgcccaag tccctgaagc agtacgcgca
     8341 cattgggtca atctgctcgg cgactatctg caacagcgca aacagcttat cgggctggtt
     8401 ttgattatgg atgcccgcca tcctttaaaa gaactcgaca tccgtatgct ggattttttc
     8461 cacacgaccg gcagaccggt tcacatcctg ctgtcaaaag ccgacaaatt atccaaaaac
     8521 gaacagataa aaaccctgtc ccaagtcaaa aaactgctca aaccttattc cgacaggcaa
     8581 aacatcagcg tacagctgtt ttccagcctg aaaaaacaag gtattgacga ggccaaccga
     8641 actgtcggaa gctggtttga cgcagcagat gccgccgctt cctctccaga ggaaaactga
     8701 ccccaattat acggaaaccg tatttccccc acttgaccga ccgcaaacat ttaaaaaatt
     8761 gccactgcca aatctaaaat gccgtctgaa agacttttca gacggcattt tgcggagtct
     8821 ttaaaacaga gaatccaact gctgctgttt ggaaccagta ttactcggaa gcaccggcgt
     8881 ttcctgcata tcttggcgga cttcgtcatc cgccgcctgc cgtccgcctt ctgccgcgcc
     8941 cccgtcatct tcttttgccc gtcgggaagg ttgcggcgca ataccgctgt tgtccagcgt
     9001 caagcccgga tcggttacca tacgttcctt catatagtat tcgccattgc tgctgaccac
     9061 accttcaggc attttcatcc ccttgccctg ctttcctttc aacgcaaaac gcatatagtc
     9121 cacccaaacc ggcaccgcaa tcgtaccgcc gtagccgaca cgccccatac tcttaggttt
     9181 gtcgaagccg atatatacgg cagtaaccac atcagggtta aaaccgacaa accacgcatc
     9241 cttattgtca ttggtcgtac ccgttttacc ggcaatatcc gttcttccca acgcagctgc
     9301 cccccttgcc gtaccgacac ggaccacatc ctgcataatc ttatacataa tataggcatt
     9361 gcgcggatcg attgcctgag gcgcattttg cccggccacc aaaggttgca tttgggcgcg
     9421 caacctgccg tctctgtcat aaatcttatc gattacgtgc gaagaaaccc tatatccgcc
     9481 gttcgcaaat acgctatatg cctccgccac tttcaacggc gttgtctcgc ccgtacctaa
     9541 agccatagac aagcttgccg gcagctcgga cgacctgaag ccgaaacgcc ggatatactg
     9601 ttgcgcgtaa ccgacaccga tagacatcaa aatacggatg gaaaccatat tcttggaagc
     9661 cgtcagagcc tgtctcaaag taatgtagcc ggaatatctg ccgtctgaat ttttaggtgt
     9721 ccaaaccgaa ccgttcggcc ctttccccgg cagggaaatc ggcgcatcgt taaccaccgt
     9781 ggacgcggtc atccccttag ataatgccgc cgaatagaca aacggcttaa aggtcgaacc
     9841 cggctgccgc attgcctgaa cggcacgatt gaatgttttg ctgtgaaaat cataaccgcc
     9901 gaccagcgcg cgcacagctc cggtttttgc atccagcgaa accaaagccc cctgcagcaa
     9961 cggctcttga accaccgccc aacgcccgcc gttgtttttg acacggatga ccgcgcccct
    10021 gcggatacgg tcctccccca ttttttcatt attgaccgcg cgggccgcaa agcccaaggc
    10081 gcgcctgtca agcgtaaccc gcctgccgcc gggcagctgt atgacgacat ttttcttttt
    10141 agtcacatcc aacacaacgg cgggaaccat tttatcgacg gtatagagtc ccgacagata
    10201 ctggctgaca gtctcctcga catcttcact cttactcaaa tcgatatagt tttccgcacc
    10261 gcggtagctg ctgccgcgat cgaaattccg tagagccttg cgcaatgcct cggttgccac
    10321 cttctgatga tcggcgcgga ccgtggtata aaccttaaaa ccctgcgtat aggcatcttc
    10381 accgtatttc tcatacagtt cctgacgcac catttccgcc acatataaag cactctgatc
    10441 gattttccga acaaaccgct cgtaatgcag ttcctcattc aacgcctgat cgcgctgttg
    10501 cacggtaatc atcttctcct cgagcatatt gttcaaaata tacttctggc gcaacttggc
    10561 acgttctgga ttaacaatcg gattataggc agacggagcc ttgggcagtc ccgcaagcat
    10621 ggcggcttcc gccaaagtca aatctcggac attcttattg aaatagattt gcgcggcaga
    10681 tgcaaaacca taggcgcgct gaccgaggta aatctgattg aaatacaact cgaggatttt
    10741 gtctttgctt aaagactgct cgattttata ggcaagcaac acctcattga atttgcgtgt
    10801 gaacgttttt tcactgctca aataaaaatt tttcgccacc tgctgcgtaa tcgtactcgc
    10861 acccgactgc acgctgccgg acacgacatt gccgacggca gcgcgggcaa caccccaaac
    10921 atccaccccc caatgccggt aaaagcgttt atcctcggcg gcgataaccg cattccgcaa
    10981 cacctctggg aaatcgccga tttttgtaaa ttcgcgccgc tgctccccat acataccgat
    11041 gacttcccca tccgccgaat aaatagtcaa cggcatttta ggctggtaat gctgcaaaga
    11101 atccaaagac ggcagtttcg gatacgttac caaaatagca atggcaacca aacccactcc
    11161 aaatacacaa aacccaaaaa ccaaaccaaa acaagtcgtt aaaatctttt taatcatagc
    11221 tgaataataa tttaccatta ttggtattaa ataaagtaaa atagcaaccg atttctacaa
    11281 agcacggttt caatgtgcaa agaacaagga atccattacg gataccgaaa cggttactca
    11341 ctgtacaaat aaagcaggaa ctttcatcat gcgcttgttt aaaagcttga aaaaccctaa
    11401 aaaaacagat gccaagctcc ctaaaaaatc ttcgggactc aataaccgcg cggcaatcgg
    11461 catcgatatc gaccagcatt ccatcaaaat ggtccaattg tcaggacgta gtttaaacca
    11521 aattcaattg gaaaaatacg tcattgccaa attaccaaag aatatcattc aaggcaataa
    11581 agtccaaaat tacgatcaac ttgttacata tttgcaacaa gcctatgcca aactgggtac
    11641 ttcgtgcaaa aacatcatcg cgtccgtccc gcaaaatctg gcaaccatcg aacaattgac
    11701 ctacacagac aaagatgcag aattagacct gcaggggttc gtggagtcct ccatctccga
    11761 agtcagctcg atatcgctcg aagaagccaa ttacgactat caggtcttgt cccaatcggc
    11821 cgccggcgaa gctgtgttgg ccgtcgcatc gagaaaggat gaaatcgaac ccctgattga
    11881 cgcattcaac gccgccggta tgaaattatc cgcgcttgat gtggacattt tcggacaata
    11941 caacgcctac gcgctatgga taaaccattt cgcccccgag cttgcggccg aaaaagtcgc
    12001 cattttcggc gtatatgccg cacagaccta cgccttggtc atccaagacg gaaaactcct
    12061 atacaaacag gaaacctccg tcagcgaaga acagctcaac caactcatcc agcgcaccta
    12121 tcaggtaaca gaagaaaaag cggaagaaat catcaactcc ccgcaaaaac cttccgatta
    12181 ccaagaaagc gtggcaaact atttcaacca gcagattacc caagaaatac aaagggtctt
    12241 gcagttttat tacaccacgc agaccgcaga cgatatgacc gacatcaagc atatcctgct
    12301 gaccggggaa gcggcgcgcc aggaaggcat cgcccaaacc gtcgcctcac aaaccaatgc
    12361 agatgtacaa tgcgtccatc ccgcgcgtta ttttgcggac aacctcaaaa cagacaaaca
    12421 acaattcgaa cttgatgcgc cgacactgac cagggcgttc ggtttggcgg tacggggatt
    12481 ataattatga acaatttaat caaaatcaac ctcctcccct acagggaaga gatgaacaag
    12541 cgcaaacagc agcagtttaa aacgctgatg tacggtgccg tgctgacggg cgttgccgcc
    12601 gttgcggcaa cctacctgtt tatcgacaat atgatcaata accagtcgga aagaaacacg
    12661 ctgctggaaa cctccatcgc acacttggat accgagctgt cggaaataca aaagctcaaa
    12721 caggaaaaag atgccttcct gattaagaaa aacaaaatcg aggagctcca gctcaaacgc
    12781 ctccaagccg caaaaatcct cgacagcctg aatgaggccg tccccggaag cacctacctg
    12841 acctcgctgg atgccgttac cgccgactct tatcggctca gcggcaggac atccagcgac
    12901 aaccgcgttg ccgccatgat gagggcgatg cccaataccg gcatattcaa gcaacccgaa
    12961 ttgttaagca tcaagaaaaa caattcgcat caagaattta cccttcaggc aacattacaa
    13021 cccatcgtaa aggcggccga atccaaagag aatccggctt cgggaaacgc acaggaggca
    13081 aactgaatgg cttctaaatc atctaaaacc aacttggatc tcaacaacct tcacctgctc
    13141 aaccttcctg ccaggctttt tatcgccctg ctggccgttg ccgccgtgct ggggctcggt
    13201 tatgccggat tgttcaaaag ccagatggaa tcccttgagg aatacgaagc aaaagaaacc
    13261 gaactgaaaa acacctacaa acagaaaagt atcgacgcgg ccagcctgaa caacctgagg
    13321 gacgaacttg cctcaatccg ctctgccttc gatatcatgt tgaaacagct gccgacagat
    13381 gcagaaattc ccaacctggt tcaagagctt catcaggcag gttcgagcaa cggcctgcgc
    13441 ttggacagcg ttatgcccca acctcccgta gatgacggcc ccatcaaaag attaccctat
    13501 tccatttcca ttaccggaaa ttacgaacag atcagccaat ttacccgcga tgtcggcagc
    13561 ctctcccgaa tcattaccct tgagtcgctg aaaatcgccc aatctccgga aaacggcggc
    13621 aatcctgacg gcaagagcag catcctgaac ctcagtgcca ttgccaccac ctaccaagca
    13681 aaatccgtag aagagcttgc cgcagaagcg gcacaaaatg ccgagcaaaa ataacttacg
    13741 ttagggaaac catgaaacac tatgccttac tcatcagctt tctggctctc tccgcgtgtt
    13801 cccaaggttc tgaggaccta aacgaatgga tggcacaaac gcgacgcgaa gccaaagcag
    13861 aaatcatacc tttccaagca cctaccctgc cggttgcgcc ggtatacagc ccgccgcagc
    13921 ttacagggcc gaacgcattc gacttccgcc gcatggaaac cgacaaaaaa ggggaaaatg
    13981 cccccgacac caagcgtatt aaagaaacgc tggaaaaatt cagtttggaa aatatgcgtt
    14041 atgtcggcat tttgaagtcc ggacagaaag tctccggctt catcgaggct gaaggttatg
    14101 tctacactgt cggtgtcggc aactatttgg gacaaaacta cggtagaatc gaaagcatta
    14161 ccgacgacag catcgtcctg aacgagctaa tagaagacag cacgggcaac tgggtttccc
    14221 gtaaagcaga actgctgttg aattcttccg acaaaaacac cgaacaagcg gcagcacctg
    14281 ccgcagaaca aaattaagaa gaggattact ccattatgaa taccaaactg acaaaaatca
    14341 tttccggtct ctttgtcgca accgccgcct ttcagacagc atcggcagga aacattacag
    14401 acatcaaagt ttcctccctg cccaacaaac agaaaatcgt caaagtcagc tttgacaaag
    14461 agattgtcaa cccgaccggc ttcgtaacct cctcaccggc ccgcatcgcc ttggactttg
    14521 aacaaaccgg catttccatg gatcaacagg tactcgaata tgccgatccc ctgttgagca
    14581 aaatcagtgc cgcacaaaac agcagccgtg cgcgtctggt tctgaatctg aacaaaccgg
    14641 gccaatacaa taccgaagta cgcgggaaca aagtttggat attcattaac gaatcggacg
    14701 ataccgtgtc cgcccccgca cgccccgccg taaaagccgc gcctgccgca ccggcaaaac
    14761 aacaggctgc cgcaccgtct accaagtccg cagtatccgt atccaaaccc tttaccccgg
    14821 caaaacaaca ggctgccgca ccgtttaccg agtccgtagt atccgtatcc gcaccgttca
    14881 gcccggcaaa acaacaggcg gcggcatcag caaaacaaca gacggcagca ccagcaaaac
    14941 aacaggcggc aacaccagca aaacaaacca atatcgattt ccgcaaagac ggcaaaaatg
    15001 ccggcattat cgaattggct gcattgggct ttgccgggca gcccgacatc agccaacagc
    15061 acgaccacat catcgttacg ctgaaaaacc ataccctgcc gaccacgctc caacgcagtt
    15121 tggatgtggc agactttaaa acaccggttc aaaaggttac gctgaaacgc ctcaataacg
    15181 acacccagct gattatcaca acagctggca actgggaact cgtcaacaaa tccgccgcgc
    15241 ccggatactt taccttccaa gtcctgccga aaaaacaaaa cctcgagtca ggcggcgtga
    15301 acaatgcgcc caaaaccttc acaggccgga aaatctccct tgacttccaa gatgtcgaaa
    15361 tccgcaccat cctgcagatt ttggcaaaag aatccgggat gaacattgtt gccagcgact
    15421 ccgtcaacgg caaaatgacc ctctccctca aagacgtacc ttgggatcag gctttggatt
    15481 tggttatgca ggcacgcaac ctcgatatgc gccagcaagg gaacatcgtc aacatcgcgc
    15541 cccgcgacga gctgcttgcc aaagacaaag ccttcttaca ggcggaaaaa gacattgccg
    15601 atctgggcgc gctgtattca caaaacttcc aattgaaata caaaaatgtg gaagaattcc
    15661 gcagcatcct gcgtttggac aatgccgaca caaccggaaa ccgcaatacg cttgtcagcg
    15721 gcaggggcag cgtgctgatc gatcccgcca ccaataccct gattgttacc gatacccgca
    15781 gcgtcatcga aaaattccgc aaactgattg acgaattgga cgtacccgcg caacaagtga
    15841 tgattgaggc gcgtatcgtc gaagcggcag acggcttctc gcgcgatttg ggcgttaaat
    15901 tcggcgcgac aggcaagaaa aagctgaaaa atgatacaag cgcattcggc tggggggtaa
    15961 actccggctt cggcggcgac gataaatggg gggccgaaac caaaatcaac ctgccgatta
    16021 ccgctgccgc aaacagcatt tcgctggtgc gcgcgatttc ctccggtgcc ttgaatttgg
    16081 aattgtccgc atccgaatcg ctttcaaaaa ccaaaacgct tgccaatccg cgcgtgctga
    16141 cccaaaaccg caaagaggcc aaaatcgaat ccggttacga aattcctttc accgtaacct
    16201 caatcgcgaa cggcggcagc agcacgaaca cggaactcaa aaaagccgtc ttggggctga
    16261 ccgttacgcc gaacatcacg cccgacggcc aaatcattat gaccgtcaaa atcaacaagg
    16321 actcgcctgc gcaatgtgcc tccggtaatc agacgatcct gtgtatttcg accaaaaacc
    16381 tgaatacgca ggctatggtt gaaaacggcg gcacattgat tgtcggcggt atttatgaag
    16441 aagacaacgg caatacgctg accaaagtcc ccctgttggg cgacatcccc gttatcggca
    16501 acctctttaa aacacgcggg aaaaaaaccg accgccgcga actgctgatt ttcattaccc
    16561 cgaggattat gggtacggcc ggcaacagcc tgcgctattg atgcgtcaaa ataagggcat
    16621 atgttttacg gcatatgccc tttctttatg ctttttgccg cgaccgaaat gccgtcattc
    16681 ccgcgcaggc agaaatccaa cttgtccggt tccggttgtt tttcgtctcg taacttttga
    16741 gccgtcattc ccgcgcaggc agaaatccag tccgttcagt ttcggtcatt tccgataaat
    16801 tcctgttgct tttcatttct ggattcccac ttttgtggga atgacggcgg agaggttttt
    16861 gttgtttcgg agaagtttct gcaaccctag aatctcgtta tttccacaaa aaacagaaac
    16921 ccgaaacagc aacttaaaac ctcgtcattc ccgcaaaagc gggaatccgg tccgttcagt
    16981 ttcggtcgtt tccgataaat tcctgctgct tttcatttct agattcccac tttcgtggga
    17041 atgacggcgg agaggttttt gttgtttcgg agaagtttct gcaaccctag aatctcgtta
    17101 tttccacaaa aaacagcaac ccaaaacggc aacttaaaac cccgtcattc ccgcgcaggc
    17161 gggaatctag gtctgtcggt tcaggacctt atcggataaa acggtttctc caaccctgcg
    17221 ttctagattc ccactttcgt gggaatgacg ggatatgggt ttccgtgcgg acgtgttcgg
    17281 atttccgcct gcgcgggaat gacggcgaca gatgcccaac ggtctttata gtggattaac
    17341 aaaaatcagg acaaggcgac gaagccgcag acagtacaaa tagtacggaa ccgattcact
    17401 tggtgtttca gcaccttaga gaatcgttct ctttgagcta aggcgaggca acgctgtact
    17461 ggtttttgtt aatccactat agtattgata aacatattat cttcaatata ttcaattgga
    17521 taattgttta cctaagcaaa gataattgcc ttttcctgac aaataagtga aatcaacgga
    17581 ttgtcaaaac acagcctgaa ataaaaaacc tccctgattt cttttatttt tccttaaaat
    17641 cagaaaggtt cgggatggtc gggttatttt tccaaacgta ccgctgccct gccgatttcg
    17701 tataaaattc cgccgtaacc cgacaagccc gaaccctgtc gccccgaaag gcggggtgtc
    17761 aaacattaag gaattgtgat gaaaaacttt aacggcaaac tcatcctcat cggactgatg
    17821 ggcgcgggca aaaccacgct gggccggcaa atggcgcagc ggctggatta ccgtttttac
    17881 gacagcgatc acgaaatcgc cgtagccgcc ggcgttccca tccccaccat atttgaaatg
    17941 gaaggcgaac agggattccg ttcgcgcgaa accgccatac tcaaaaagct ggttatcctg
    18001 ccccatatcg tcctgtccac cggcggcggc gcggtgttaa aagaagaaaa ccgcgccctt
    18061 atccgcaaaa gcggcacggt cgtctatctg cacgccccgc ccgaaaccct gctcgaacgc
    18121 acgcgctgcg acaacagccg tcctttgctg caagttgccg atcctttggc gaaattacgt
    18181 gaactctacg ccgcacgcga ccccgtttac cgccaaaccg ccgactttac cgtagaatcg
    18241 gcaaactgcc gggaaaccgt gcaaaccctg ctcaaacgct tatcccgata aaccggcata
    18301 tgcgccgcgc ccagaaaacc aagccgcgcc ccgcccggcg ggccggcggt tcaaacttta
    18361 aggaacaaca atgaaaacac tgaccgtaca caccccgtcc cacagctacc ccatctttat
    18421 cggcaacggg ctgctgccgc aggcaggaag cctgctcaaa ccgcatttgg gcaaacgcgc
    18481 cgccatcatc gccaacgaaa ccgtcgcccc gctctacctc ggcacgcttc agacggcatt
    18541 ggatgcggca ggcgtatccc atttcagcat catcctgccc gacggcgagg cgcacaaaaa
    18601 ctggcagacg ctcaacctca tctttgacgg gctgatgcaa aaccgcgccg aacgcaaaac
    18661 cacattaatc gcactgggcg gcggcgtgat cggcgacatg gtcggctttg ccgctgccac
    18721 ctaccagcgc ggcgcaccgt tcgttcaaat accgaccaca ctgttgagtc aagtcgactc
    18781 atcggtgggc ggcaaaaccg ccatcaacca cccgctcggc aaaaatatga tcggcgcatt
    18841 ctaccagccg caggcggtgc ttgccgactt ggacacgctg cacaccctgc ccgtccgcga
    18901 attgtccgcc ggtatggcgg aagtcatcaa atacggcgcg ctcggcgaca tcggtttttt
    18961 cgaatggctc gaacaaaaca tatccggact gatgacgctc gatcgggaaa aactcgccca
    19021 agccgtgtac cgctgctgcc aaatgaaggc agacatcgtc gcccaagacg aaaccgaaca
    19081 gggcatacgc gcatggctca acctcggaca caccttcgga cacgccattg aaaccgagat
    19141 gggttacggc acttggctgc atggagaagc catcgccgcc ggctgcgtgt tggcggcgcg
    19201 tttgtccgaa caactgggca aaacctccgc cgcagatacc gcgcggctcg ccgccctgct
    19261 cgaagccgcc ggactgccgt ccgcaccgcc cgtgtttgcc tttgaaaaat ggctcgaaca
    19321 tatgagccac gataaaaaag tcagcggcgg catcatgcgc tttatcggtc tgaaccggct
    19381 gggcgaagcc aacatcaccg aaattaccga cacggacatc ctccgccgca ccctgcaacc
    19441 gtatctctga tttcctctgc caatgtgctg ccgcgcgggt ttgacgcacg atgatgattt
    19501 tccatcatct ttctccgtaa aagcgggaat ccggtccgtt cggtttcggt cgtttccgat
    19561 aaattcctgc tgcttttcat ttctagattc ccactttcgt gggaatgacg gcggagaggt
    19621 ttttgttgtt tcggagaagt ttctgcaacc ctagaatctc gttatttcca caaaaaacag
    19681 aaacccaaaa cagcaactta aaacctcgtc attcccgcaa aagcgggaat ccggtccatt
    19741 cagtttcggt cgtttccgat aaattcctgc tgcttttcat ttctagattc ccactttcgt
    19801 gagaatgacg gcggaagggt tttggttttt tccgataaat tcttgaggca ttgaaattct
    19861 atagtggatt cacaaaaatc aggacaaggc gacgaagccg cagacaatac agatggtacg
    19921 gaaccgattc actcgtgctt cagcacctta gagaatcgtt ctctttgagc taaggcgaga
    19981 caacgccgta ccggtttttg ttaatccact ataacagcaa ccctgtcgcc gtcattcccg
    20041 caaaagcggg aatccagtcc gttcggtttc ggtcgtttcc gataagttcc cgttgctttt
    20101 catttctaga ttcccacttt cgtgggaatg acggcggaag ggttttggtt ttttccgata
    20161 aattcttgag gcattgaaat tccagattcc cgcctgcgcg ggaatgacgg ctcaaaagtt
    20221 acggaacgaa aaacaaccaa aaccggacaa gtcggattcc cgcctgcgcg ggaatgacgg
    20281 aatcttaagt ttccgtcttt gttttctgtt ttctgttttc gagggaataa cggggaacaa
    20341 gccgtatttc agacggcatt ttcagttcgg ggtataatcc gaatacttgc gaccatctga
    20401 atcattggga caaaccatgt gtcaactgct gggcatgaac tgcaatacgc cgaccgatat
    20461 tatgttttcc tttgaaggct tccgccgcag gggcggcatt accgaccacc atgccgacgg
    20521 tttcggcatc ggctttttcg aaggcaaagg cgtgcgcctg ttccatgacg acaaacccag
    20581 tgccaattcg cccgtcgccg acctcgtgcg cgcctaccag attaaatcgg aaaacgtcgt
    20641 cgcccatatc cgcaaagcat cacaaggaca aacctcgctg gcgaacaccc atccctttat
    20701 gcgcgaaatg tggggcggct actggctgtt tgcccacaac ggacatttga ttgatttttt
    20761 tcccgaacag ggcgaatttt tccaccccgt cggcacaacc gattccgaac gcgcgttctg
    20821 ccacatcctc aaccgcctgc gcacccgctt tgccgcccgt cccgacgacg acacgctgtt
    20881 tgacgcgatt gcggggctga cgcacgaaat ccgcaagttc gggctgttta actttatgct
    20941 ttcagacggc attgccctgt ttgcccacgc cagcacacta ctgcactaca tcgtccgcca
    21001 agccccgttc ggcaaggcgc gcctgctcga cgacgacgtg atggtcgatt ttgccgaagt
    21061 aaccacgccc aacgaccgcg tcgccgttat cgccaccctg ccgctgaccc gcgacgaatc
    21121 atggtcccaa cttgccgtga acgaactggt catgttccgc gaaggcaaca tcgtccgaca
    21181 cgaccgtccc gaaaaccccg tctatatgag tgccgaagaa ggtctggaaa tcgcccgcgc
    21241 cgccggcgta tcggtttgac gttcagacgg catcaggaag aaacgctatg aaatgcccgt
    21301 tttgcgccca ccccgacacc cgcgtcgccg attcgcgtct gatggaagaa cgcaacgccg
    21361 tgcgccgccg ccgccactgc cccaactgcg gcaaacgctt cggcacgctc gaaaccgccg
    21421 aactcaaaat gcccgccgtc atcggcacgg acaaaaaacg ctcgcccttt aatgcacaac
    21481 gcctccgcaa cgacctgacc gccgccgccc gaaaatccgc cctgacaccc gaacagatcg
    21541 acgaaaccgt ccgcctgacg gaacacaggc tctacacttc gggtcagcgc gacatcccct
    21601 ccaccgaact tgccgacatg gtgctaaaag agctgcttga gcacaacacg gaagccgccg
    21661 tccgcttcgc cgccctgcac aaacgcttcg acaatccgtc agactttgcc tcgtggctgg
    21721 cgcaagccgt caaaacagac cgcaaagcct gattctcccc aacccatact gatacggtat
    21781 ccctatgttt tcggacacag atatatccat gatggaaatc gccctccgac ttgccgcttt
    21841 gggacgtttt tccacttcgc ccaatccgcg cgtcggctgc gttatcgcac acggcagcca
    21901 aattgtcggg caaggcttcc acgtcaaagc gggcgaaccg cacgccgaag tccacgccct
    21961 gcatcaggcg ggggaaatgg caaaaggcgc gaccgccttt gttaccctcg aaccgtgcag
    22021 ccattacggg cgtaccccgc cctgtgccga agctctgctc cgttccggcg taacacgcgt
    22081 cgttgccgcc atgcgcgacc ccaacccgct ggttgccggc aaagggcttg ccctgctcga
    22141 agcagcaggc atcaagacgg aatgcggttt actcgaacat caggcaagga aactcaaccg
    22201 aggcttcctg tcgcgcatcg aacgccgccg cccctttgtc cgcctcaaat gcgccgtttc
    22261 gctggacggc aaaaccgccc tttcagacgg cagcagcttt tggattaccg gcgaagacgc
    22321 gcgtgccgac gtacaggttt tgcgtgccga aagctgcgcg gtgctgaccg gcatcggcac
    22381 ggtgttggcg gacaatcccc ggctcaacgt ccgcgctttt ccaactttgc gccaacccgc
    22441 acgcatcgtt ttagacagcc gcctgcgcct gcccccgaac agccatttgg ttaccgacgg
    22501 acaatctccg acctacatcg ccacactcga acgcaacgaa gacagactgc acccctatcg
    22561 ggaacacgca cacgtccgca tcctgatgcc gtctgaaacg gcagacagca aaatcgacct
    22621 gcaccacctg atgcgcctcc ttgctgacga aggtttcggc gaaatcatgg tcgaagcagg
    22681 ctccgaactc acatccgcat ttttggcaga aaatctggca gacgaaatcg tcctgtaccg
    22741 ttcgcccaaa atcctcggca gcggcaaaga cctgttttcc ctgctcgaaa accgcgccgc
    22801 cctttccgca ccgcccttgt ggacacccgt ttcaagcgaa atcctcggac acgacatcaa
    22861 aaccgtgttc cgaaaaaacg gcaacgcctt ttaaagggtt tgcgccgttt cactatataa
    22921 taacgccgat aaaaaacggc accattcaga ccgccgccca cccgaaaaaa cgcaacccgg
    22981 actgccgcac cccgccggca gccgcgacgg tctgaaagcc gtcaaattcc gatcaagaaa
    23041 ggcttcagac ggcacaggca gcatcccgcc gccgcccgga catcaaaaat ggacacaaaa
    23101 gaaatcctcg gctacgcggc aggctcgatc ggcagcgcgg ttttagccgt catcatcctg
    23161 ccgctgctgt cgtggtattt ccccgccgac gacatcgggc gcatcgtgct gatgcagacg
    23221 gcggcgggac tgactgtgtc ggtattgtgc ctcgggctgg atcaggcata cgtccgcgaa
    23281 tactatgccg ccgccgacaa agacaccttg ttcaaaaccc tgttcctgcc gccgctgctg
    23341 tctgccgccg cgatagccgc cctgctgctt tcccgcccgt ccctgccgtc tgaaatcctg
    23401 ttttcgctcg acgatgccgc cgccggcatc gggctggtgc tgtttgaact gagcttcctg
    23461 cccatccgct ttctcttact ggttttgcgt atggaagggc gcgcccttgc cttttcgtcc
    23521 gcgcaactcg tgtccaagct cgccatcctg ctgctgctgc cgctgacggt cgggctgctg
    23581 cactttccgg cgaacaccgc cgtcctgacc gccgtttacg cgctggcaaa ccttgccgcc
    23641 gccgcctttt tgctgtttca aaaccgatgc cgtctgaagg ccgtccggcg cgcaccgttt
    23701 tcatccgccg tcctgcatcg cggcctgcgc tacggcatac cgatcgcact gagcagcatc
    23761 gcctattggg ggctggcatc cgccgaccgt ttgttcctga aaaaatatgc cggcctagaa
    23821 cagctcggcg tttattcgat gggtatttcg ttcggcggag cggcattatt gttccaaagc
    23881 atcttttcaa cggtctggac accgtata
//
LOCUS       DAXISH010000028        23879 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.028, whole genome shotgun sequence.
ACCESSION   DAXISH010000028 DAXISH010000000
VERSION     DAXISH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 23879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23879
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.028"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..236
                     /locus_tag="ACFOV4_001104"
     CDS             <1..236
                     /locus_tag="ACFOV4_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="opacity family porin"
                     /protein_id="HFC7619128.1"
                     /translation="GAGATEPGKIISGPISKPAYHESHSTSSLGLGVIAGVGFDITPK
                     LTLDTGYRYHNWGRLENTRFKTHEVSLGMRYHF"
     gene            complement(210..419)
                     /locus_tag="ACFOV4_001105"
     CDS             complement(210..419)
                     /locus_tag="ACFOV4_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619129.1"
                     /translation="MPSERLSDGIFPCVLNRIHETPDAFGGNVGCRAMFGGDQRTKCA
                     GKGLMPSEGSDGIGIGESEVVAHAQ"
     gene            complement(437..994)
                     /locus_tag="ACFOV4_001106"
     CDS             complement(437..994)
                     /locus_tag="ACFOV4_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFC7619130.1"
                     /translation="MDALKLLTNRRSSKKLKHPAPDAAELEQIFQAATQVPDHGNMRP
                     FRFTVIQGEVGLQRFRDVLKQTVAELNFGDDAMKKAEKVGNMAPMVIGVTFAPNRDVP
                     KPKPEWEQMLTAGCAAYALQLAATAQGFDNVWITGMWVNSPLLREAFGCADKDKIIGL
                     MMVGTPTEEVHKPKNTDLEAFVSHW"
     gene            complement(1070..2704)
                     /locus_tag="ACFOV4_001107"
     CDS             complement(1070..2704)
                     /locus_tag="ACFOV4_001107"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:1900727 - osmoregulated periplasmic glucan
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HFC7619131.1"
                     /translation="MIKPNLRPKLGSSALIAFLSLYSSLVLNYAFFAKVVELHPFNGT
                     GADIFLYTMPVVLFFLSNFVFHVIALPFVHKVLIPLILVISAAVSYQEIFFNIYFNKS
                     MLNNVLQTTAAESARLITPGYVLWIVCLGVLPALAYIAVKVKYRVWYKELLTRLVLAA
                     VSFLCALGIAMLQYQDYASFFRNNKSVTHLIVPSNFIGAGVSKYKDWKRSNIPYTQLD
                     MAVVQNRPAGSLRRFVVLVVGETTRAANWGLNGYSRQTTPLLAARGDEIVNFPQVRSC
                     GTSTAHSLPCMFSTFDRTDYDEIKAEHQDNLLDIVQRAGVEVTWLENDSGCKGVCGKV
                     PNTDVTSLNLPEYCRNGECLDNILLTKFDEVLNKNDKDAVLILHTIGSHGPTYYERYT
                     EAERKFTPTCDTNEINKCTRATLVNTYDNTVLYVDQFIDKVIRKLENRDDLESAVHYV
                     SDHGESLGENGMYLHAAPYAIAPSGQTHIPMVMWFSKAFRQHGGIDFQCLKQKAAENE
                     YSHDHYFSTVLGLMDISNSQTYRKEMDILAACRRPR"
     gene            complement(2985..4091)
                     /gene="serC"
                     /locus_tag="ACFOV4_001108"
     CDS             complement(2985..4091)
                     /gene="serC"
                     /locus_tag="ACFOV4_001108"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine transaminase"
                     /protein_id="HFC7619132.1"
                     /translation="MSLYPIYNFSAGPAVLPEAVLETARQEMLDYNGTGFPVMAMSHR
                     SEMFLSILHHAEQDLRQLLKVPDNYKILFLQGGATTQFNMAAMNLAHGFRTADAVVTG
                     NWSRIAYEQMSRLTDTEIRLAAHGGEQFDYLDLPPVETWDVAPDSAFVHFAVNETVNG
                     LQYREVPRLSEGMPPLVCDMSSEILSREFDVADYGLIYAGAQKNIGPAGATVVIIRED
                     LLERCPNDIPDVFNYRSHINRDGMYNTPSTYAIYMSGLVFRWLQAQGGVKKIEAVNRL
                     KAQTLYETIDGSGGFYINRIRPNARSKMNVVFQTEDEELDRRFVLEAELQGLCLLKGY
                     KTVGGMRASIYNAMPLEGVRALADFMRDFQRRYG"
     gene            4456..4887
                     /gene="rimP"
                     /locus_tag="ACFOV4_001109"
     CDS             4456..4887
                     /gene="rimP"
                     /locus_tag="ACFOV4_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003685973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFC7619133.1"
                     /translation="MDIQTILEKTLPGLGYELVDFELTAQGTLRVFIDKEGGITVEDC
                     ATVSNHLSRVFMVEDIDYKNLEISSPGLDRPLKKAADFVRFAGQNAKIKTRLPIDGQK
                     NFIGKIEGCENDTVTVSFDGKTVQIELGNIDKARLRPEFKF"
     gene            4915..6417
                     /gene="nusA"
                     /locus_tag="ACFOV4_001110"
     CDS             4915..6417
                     /gene="nusA"
                     /locus_tag="ACFOV4_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFC7619134.1"
                     /translation="MSREMLQLAEALASEKNVDAEVVFQALEFALSTAAKKKADREHM
                     DVRVQINRDTGEYQTFRRWLIVADEDYTYPDVEKTIEEIQEEIPGTTIQIGEYYEEQL
                     PNEGFGRQAAQTAKQIILQRIRDAEREQNLNEFLAVKEDIVSGTVKRVERHGIIVEVV
                     AGKLDALIPRDQMIPRENFRSGDRIRALFLRVEEIGNTGRKQVILSRTSGDFLVKLYA
                     NEVPEIADGMLEIRAVARDPGQRAKVAVKANDQRIDPQGTCIGVRGSRVNAVSNELSG
                     ERIDVVLWSPEPAQFVMSALSPAEVSRIVIDEDKHAVDVIVAEDQLALAIGRGGQNVR
                     LASDLTGWQLNIMTSAEADERNAAEDAAIRRLFMDHLNVDEETADVLVQEGFATLEEV
                     AYVPAAELLAIEGFDEEIVDMLRNRARDAILTMAIAAEEKLGEVSDDMRNLEGVDADM
                     LRSLAEAGITTRDDLAELAVDELIEITGVNEETAKAVILTAREHWFTEDK"
     gene            6430..9318
                     /gene="infB"
                     /locus_tag="ACFOV4_001111"
     CDS             6430..9318
                     /gene="infB"
                     /locus_tag="ACFOV4_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFC7619135.1"
                     /translation="MSNTTVEQFAAELKRPVEDLLKQLKEAGVSKNSGSDSLTLDDKQ
                     LLNAYLTKKNGSNGGTISIRRTKTEVSTVDGVKVETRKRGRTVNIPSAEELAAQVKAA
                     QTQAAPVRPEQTAEDTAKARAEAAARAEARAKAEAEAAKLKAAKAGNKAKPAAQKPTE
                     AKAETAPVAAETKPAEESKAEKAQADKMPSKKPAEPKEKAAKPKHERNGKGKDAKKPA
                     KPAAPAVPQPVVSAEEQAQRDEEARRAAALRAHQEALLKEKQERQARREAMKQQAEQQ
                     AKTAQEAKTGRQRPAKPAEKPQAAAPAVENKPVNPAKAKKEDRRNRDDEGQGRNAKGK
                     GGKGGRDRNNARNGDDERVRGSKKGKKLKLEPNQHAFQAPTEPVVHEVLVPETITVAD
                     LAHKMAVKGVEVVKALMKMGMMVTINQSIDQDTALIVVEELGHIGKPAAADDPEAFLD
                     EGAEAVEAEALPRPPVVTVMGHVDHGKTSLLDYIRRTKVVQGEAGGITQHIGAYHVET
                     PRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIAHAKAAGVPM
                     VVAVNKIDKEAANPERIRQELTAHEVVPDEWGGDVQFIDVSAKKGLNIDALLEAVLLE
                     AEVLELTAPVDAPAKGIIVEARLDKGRGAVATLLVQSGTLKKGDMLLAGTAFGKIRAM
                     VDENGKSITEAGPSIPVEILGLSDVPNAGEDAMVLADEKKAREIALFRQGKYRDVRLA
                     KQQAAKLENMFNNMGETQAQSLSVIIKADVQGSYEALAGSLKKLSTDEVKVNVLHSGV
                     GGITESDVNLAIASGAFIIGFNVRADASSRKLAENENVEIRYYNIIYDAIDDVKAAMS
                     GMLSPEEKEQVTGTVEIRQVISVSKVGNIAGCMVTDGVVKRDSHVRLIRNNVVIHTGE
                     LASLKRYKDDVKEVRMGFECGLMLKGYNEIMEGDQLECFDIVEVARTL"
     gene            complement(9529..10923)
                     /locus_tag="ACFOV4_001112"
     CDS             complement(9529..10923)
                     /locus_tag="ACFOV4_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase/DUF3482 domain-containing protein"
                     /protein_id="HFC7619136.1"
                     /translation="MNKQPLSLAVVGHTNTGKTSLLRTLLRDSGFGEVRNAPSTTRHV
                     EEAAISDGADTLVFLYDTPGLEDAGGVLEWLENHTDNRSDGIERLQQFLGSHGAHHDF
                     NQEAKVLRQVLQSDMAMYVIDAREPVLDKYRDELTILSWCAKPVMPVFNFTGGQPPES
                     WTTMLARRNLHVFAGFDTVAFDFEGELRLWENLATMLPERSTLDRLTAMRRREWQRLD
                     GEARREIADFLIDAAAFRQEVDENEDTATVLQTMQAEIRQLERQMQQRLFALYRFYHS
                     EIDGGDWMPQAFRQDPFDSELLKQYGIRTGTGAATGALIGLGLDIATLGGSLGLGTAI
                     GGFLGGILPNTRTISDKLSGRQTLHTDPETLTLLAARALDLLHVLQTRGHAAQSDIEL
                     HSRKAPWDAARLPPELNKARSHWKWSSLNTHRPETSRAERAGYVEKLQIRLSGKYSEL
                     NLNQDKAASRRQYK"
     gene            complement(10997..12337)
                     /locus_tag="ACFOV4_001113"
     CDS             complement(10997..12337)
                     /locus_tag="ACFOV4_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2868 domain-containing protein"
                     /protein_id="HFC7619137.1"
                     /translation="MLNPSRKLVELIRILDEGGFIFSGDPVQATEALRRVDGSTEEKI
                     IRRAEMIDRNRMLRETLERVRAGSFWLWVAAATFAFFTGFSGTYLLMDNQGLNFFLVL
                     AGVLGMNTLMLAVWLAMLFLRVKVGRFFSSPATWFRGKDPVNQAVLRLYADEWRQPSV
                     RWKIGATSHSLWLCTLLGMLVSVLLLLLVRQYTFNWESTLLSNAASVRAVEMLAWLPA
                     KLGFPVPDARAVIEGRLNGNIADARAWSGLLVGSIACYGILPRLLAWAVCKILLKTSE
                     NGLDLEKPYYQAVIRRWQNKITDADTRRETVSAVSPKIVLNDAPKWAVMLETEWQDGE
                     WFEGRLAQEWLDKGVAANREQVAALETELKQKPAQLLIGVRAQTVPDRGVLRQIVRLS
                     EAAQGGAVVQLLAEQGLSDDLSEKLEHWRNALAECGAAWLEPDRAAQEGRLKDQ"
     gene            12480..13106
                     /locus_tag="ACFOV4_001114"
     CDS             12480..13106
                     /locus_tag="ACFOV4_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFC7619138.1"
                     /translation="MYTGERFNTYSHLSGLILAAAGLALMLLKTIGHGDGYRIFSVSV
                     YGISLLLLYLSSSLYHGIAAGKLKSILKKTDHCMIYVLIAGSYTPFALVSLRNGPGWT
                     VFSLSWLLAAAGIAQELTIGRKSEKRLLSIAIYVVMGWMVLAVMKSLTASLPPAGLAW
                     LAAGGMLYSVGIYWFVNDEKIRHGHGIWHLFVLGGSITQFVSVYGYVI"
     gene            complement(13170..14588)
                     /locus_tag="ACFOV4_001115"
     CDS             complement(13170..14588)
                     /locus_tag="ACFOV4_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFC7619139.1"
                     /translation="MENILSVLVGTVNRFLWDYLLIYALLGIGLFFTLYLGAPQITKL
                     GAGFKSVFGGLFAKGDKDDKSLSQFQALAVAISAQIGTGNVAGVATAITAGGPGAIFW
                     MWVSAVLGMSTIFAEALLAQKYRVVSHGKYIGGPAFYITHGLTPKIGRGAARFLSGFF
                     SIALIIALGFIGNATQANSIASAVTIAFDVPSLAVGIVLAVLAGMVVIGGVNRIANIA
                     QFVVPFMAVVYILCAVVILFEFSDHIVPMFNHIFTAAFNPEAVLGGAAGIGMREAVRF
                     GVARGLFSNEAGMGSTPHAHATADVKHPVQQGMAAFVGVFIDTILVCTATALIILLTD
                     ANLSGEQGAAVTQFAFNKAFPGFGSQLLAVCLTFFALTTIIGWYYFGESNIRFLFRGR
                     HLGIYRALVLLAIVLGTLGKVDLVWSLSDMFNGFMVIPNLIALFLLRKEIRAIYDDYL
                     AQKKAGRDLSYQYEFHEFHDKG"
     gene            14915..15643
                     /locus_tag="ACFOV4_001116"
     CDS             14915..15643
                     /locus_tag="ACFOV4_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004285004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFC7619140.1"
                     /translation="MAGHSKWANIQHKKARQDAKRGKIFTRLIKEITVAARMGGGDPG
                     SNPRLRLALEKAAENNMPKDNVQRAIDKGTGNLEGVEYIELRYEGYGIGGAALMVDCL
                     TDNKTRTVADVRHAFTKNGGNLGTDGCVAFNFVHQGYLVFEPGVDEDALMEAALEAGA
                     EDVVTNDDGSIEVITAPNDWAGVKSALEAAGYKSVDGDVTMRAQNETELSGDDAVKMQ
                     KLIDALEDLDDVQDVYTSAVLNLD"
     gene            complement(15702..16190)
                     /locus_tag="ACFOV4_001117"
     CDS             complement(15702..16190)
                     /locus_tag="ACFOV4_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein B"
                     /protein_id="HFC7619141.1"
                     /translation="MTPLFRKAVWLLFAVSVCAFAGSLAAQYVLGMEPCVLCISQRLC
                     VLATALCTAIVLMCRPRRRAGGLFGAVFISIPAVTGISVAAYQLWLQSLPPGTAPSCG
                     APWTFRLKGWSLFDWFEPVVRGFGNCAEPDYLLGVALPVWSAAYFLAVVLTVWWAWAR
                     AK"
     gene            complement(16949..17413)
                     /locus_tag="ACFOV4_001118"
     CDS             complement(16949..17413)
                     /locus_tag="ACFOV4_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFC7619142.1"
                     /translation="MKELDKIDFRILKILQQNARIPMTELAEKVGLSTTPVTERVRRL
                     EREHYISGYHAHLNPHLLGKPLLVFVELKLQSKSGNIFEDFKKEVLKIPQIMECHLVS
                     GEYDYLIKVRLPDMSAYRDMLGNILLQLPAASESRSYVVMEEVKENPVLDLD"
     gene            complement(17423..17553)
                     /locus_tag="ACFOV4_001119"
                     /pseudo
     CDS             complement(17423..17553)
                     /locus_tag="ACFOV4_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            17738..18796
                     /gene="alr"
                     /locus_tag="ACFOV4_001120"
     CDS             17738..18796
                     /gene="alr"
                     /locus_tag="ACFOV4_001120"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFC7619143.1"
                     /translation="MRPLNVQIRLGNLRHNYRILKEMHGGKLLAVVKADAYGHGAVRC
                     AFALADLADGFAVATIDEGIRLRESGITHPIVLLEGVFEASEYEAVEQYSLWPAVGNQ
                     WQLEALLSRHWKKPVKVWLKMDSGMHRTGFFPHDYASAYAALKQSEYVDSIVKFSHFS
                     CADEPESGMTEIQMEAFDLGTEGLEGEESLANSAAILNVPEARRDWGRAGLALYGISP
                     FGGSDDRLKPVMRLSTRIFGERVLQPHSPIGYGATFYTSKSTRVGLIACGYADGYPRR
                     APSNSPVAVDGKLTRVIGRVSMDMMTIELDASQEGLGHEVELWGDTVNINTVAEAAGT
                     IPYELMCNIKRAKFTYIE"
     gene            complement(18860..20215)
                     /locus_tag="ACFOV4_001121"
     CDS             complement(18860..20215)
                     /locus_tag="ACFOV4_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HFC7619144.1"
                     /translation="MSIQSGEILETVKMVADQNFDVRTITIGIDLHDCISSDINVLNQ
                     NIYNKITTVGKDLVATAKYLSAKYGVPIVNQRISVTPIAQIAAATHADSYVSVAQTLD
                     KAAKAIGVSFIGGFSALVQKGMSPSDEVLIRSIPEAMKTTDIVCSSINVGSTRAGINM
                     DAVKLAGETIKRTAEITPEGFGCAKIVVFCNAVEDNPFMAGAFHGSGEADAVINVGVS
                     GPGVVKAALENSDATTLTEVAEVVKKTAFKITRVGELIGREASKMLNIPFGILDLSLA
                     PTPAVGDSVARILEEMGLSVCGTHGTTAALALLNDAVKKGGMMASSAVGGLSGAFIPV
                     SEDEGMIAAAEAGVLTLDKLEAMTAVCSVGLDMIAVPGDTPAHTISGIIADEAAIGMI
                     NSKTTAVRIIPVTGKTVGDSVEFGGLLGYAPVMPVKEGSCEVFVKRGGRIPAPVQSMK
                     N"
     gene            complement(20230..20502)
                     /locus_tag="ACFOV4_001122"
     CDS             complement(20230..20502)
                     /locus_tag="ACFOV4_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFC7619145.1"
                     /translation="MNNSVITVIGKDRVGIVYDVSKILAENRINILNISQQLMDDFFT
                     MIILVDTSKCPKSRQEVLDLFAEESKKLALDIRMQNEEIFQAMHRI"
     gene            complement(20628..21365)
                     /locus_tag="ACFOV4_001123"
     CDS             complement(20628..21365)
                     /locus_tag="ACFOV4_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system YwqK family antitoxin"
                     /protein_id="HFC7619146.1"
                     /translation="MKKLSRIVFSIVLLGFSASLSAQTYSVYFNQNGKLTATMSSAAY
                     IRQYSVAEGIAYAQDFYYPSMKKYSEPYIVASTQIKSFVPTLQNGMLILWHFNGQKKM
                     AGGFSKGKPDGEWVNWYPNGKKSAVMPYKNGLSEGTGYRYYRNGSKESEIQFKQNKAN
                     GVWKQWYADGNIKTEMVMVNDEPAKILTWDESGRLLSELSIHHHKRNGVVLEWYEDGS
                     KKSEAVYQDDKLVRKTQWDKDGYLIEP"
     gene            complement(21646..22545)
                     /gene="prmB"
                     /locus_tag="ACFOV4_001124"
     CDS             complement(21646..22545)
                     /gene="prmB"
                     /locus_tag="ACFOV4_001124"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA];
                     GO_process: GO:0042273 - ribosomal large subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFC7619147.1"
                     /translation="MFNQAAQELTTIRDVLRFAVSRFNEAGLFFGHGTDNAHDEAAYL
                     ILHTLNLPLDMLAPYLDAKLLEAEKEEVLTVIERRAVEHIPAAYLTHQAWQGEFDFYV
                     DERVIIPRSFIYELLGDGLRPWIEYDELVHNALDLCTGSGCLAIQMAHHYPDAQIDAV
                     DVSLDALEVAGINVEDYGLEERIRLIHTDLFEGLEGTYDLIVSNPPYVDAESVELLPE
                     EYLHEPELALGSGADGLDATRQILLNAAKFLNPKGVLLVEIGHNRDVLEAAYPELPFT
                     WLETSGGDGFVFLLTREQLLGEE"
     gene            22690..23283
                     /locus_tag="ACFOV4_001125"
     CDS             22690..23283
                     /locus_tag="ACFOV4_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619148.1"
                     /translation="MADGMGNLIGWEKTGLVAGKQWITAKDDKVSDVCNANGEMGVIG
                     LYEPFSHGALTIPGHPNCRCEVVSVSGGELGEFAEKKELRKAAMQYARDNFIGKSYVN
                     ENSGHELKVTWQGVKHAASKANQAELSIMTKLDDLLRYAKYEGSYSDRKGHPNIIAAH
                     KYRAVAKVGNESLNIGVIVREFPDDHKHYDHFILKDE"
     gene            23395..>23879
                     /locus_tag="ACFOV4_001126"
     CDS             23395..>23879
                     /locus_tag="ACFOV4_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFC7619149.1"
                     /translation="MTKLYAEIAKMETQDDDTVKVWGYASSEEIDSDGEVIATAAMKA
                     AIPDYMKFGEGREMHGSNAAGTAIEINVEDDGITFFGAHIIDPVVVAKVKTGVYKGFS
                     IGGSVTARDDLNKSQITGLKLTEISLVDRPANPDAVFTCFKADKGAEAVNNDTEHNAT
                     Y"
BASE COUNT         6315 a         6476 c         5888 g         5200 t
ORIGIN      
        1 caggggcagg tgctacagag ccaggcaaaa ttatatcagg tccgatctcc aaacctgcct
       61 atcacgaaag ccacagcacc agcagcttgg gtcttggtgt catcgccggt gtcggtttcg
      121 acatcacgcc caagctgacc ttggacaccg gataccgtta ccacaactgg ggacgcttgg
      181 aaaacacccg cttcaaaacc cacgaagtct cattgggcat gcgctaccac ttctgattcc
      241 ccgataccga tgccgtctga accttcagac ggcatgagac ctttgcctgc gcacttggtg
      301 cgctggtcgc ctccgaacat ggcgcgacac ccgacatttc cgccgaacgc atcgggcgtt
      361 tcatgaatcc ggtttaaaac gcatggaaaa atgccgtctg aaagcctttc agacggcatt
      421 gtgcttgaga ttccgtttac caatggctga caaacgcttc caaatcggta ttcttgggct
      481 tatgcacttc ctctgtcggc gtgccgacca tcatcagccc gatgatttta tccttatccg
      541 cacaaccgaa agcctcccgc aacaaggggc tgttgaccca catccccgta atccagacat
      601 tgtcgaatcc ctgagccgtt gccgccagtt gcagcgcata cgccgcacaa cccgccgtca
      661 gcatctgctc ccattccggt ttcggcttag gcacatcacg attcggcgca aacgttaccc
      721 cgatgaccat cggcgccata ttgcccactt tttccgcctt tttcatcgca tcgtcgccga
      781 aattcaattc ggcaaccgtt tgctttaaca catcgcgaaa acgttgcaat cctacctcgc
      841 cttgaatcac ggtaaaacgg aaggggcgca tattgccgtg atcgggaact tgggttgccg
      901 cctgaaatat ttgttccaac tccgccgcat cgggggcggg gtgcttcagc tttttggaag
      961 atcggcggtt cgtcaataat tttaaagcat ccatatcgtt atactccggt catcggtcgg
     1021 gtgttcggac acatatgccg tccgaaggct tcagacggca tatccggcat cagcgcggac
     1081 ggcggcaggc tgccaatata tccatttcct tccgataggt ttggctgttg gaaatgtcca
     1141 tcagccccaa taccgtgctg aaatagtggt cgtgcgaata ttcgttttcc gccgcttttt
     1201 gtttgaggca ttggaaatct atgcccccgt gttggcggaa ggctttggaa aaccacataa
     1261 ccatcgggat atgcgtctgc ccggaaggcg cgatggcgta aggcgcggcg tgcaggtaca
     1321 tcccgttttc gcccaaactt tcgccgtggt cggaaacata atgcaccgcg ctttccaaat
     1381 cgtcgcggtt ttcaagtttg cggataacct tgtcgataaa ctggtccaca tacaaaaccg
     1441 tattgtcgta agtgttgacc agcgtggcgc gggtgcattt gttgatttcg ttggtgtcgc
     1501 aggtcggcgt gaatttgcgt tcggcttcgg tatagcgttc gtaatacgtc ggcccgtggc
     1561 tgccgatggt atgcaggatt aaaaccgcgt ctttatcgtt tttgttgagg acttcgtcga
     1621 acttagtcag caggatattg tcgagacact cgccgttgcg gcagtattcg ggcaggttga
     1681 gcgaggtaac gtcggtattc ggcactttgc cgcacacgcc cttgcagccg gaatcgtttt
     1741 ccaaccaggt aacttccacg ccggcgcgct gcacgatgtc cagcaggttg tcttggtgtt
     1801 cggctttgat ttcgtcataa tccgtgcggt cgaaggttga gaacatacac ggcagggagt
     1861 gcgcggtcga tgtgccgcag cttctgacct gcgggaaatt gacaatttca tcgccgcgcg
     1921 cggcaagcag cggcgtagtt tggcggctgt aaccgttcaa accccagttg gcggcacgcg
     1981 tggtctcgcc cacgaccagc accacgaaac ggcgcaggct gccggccggc cggttttgca
     2041 cgaccgccat atccaattgc gtataaggaa tattggaacg cttccaatct ttgtatttcg
     2101 acacgcccgc gccgatgaaa ttagacggca caatcagatg ggttactgat ttattgttgc
     2161 ggaaaaacga ggcgtaatcc tgatattgca acattgcgat gcccaacgcg cacaaaaagg
     2221 aaacggcggc aagcacaagg cgcgtcaaaa gctccttata ccaaacgcgg tatttaacct
     2281 tgacggcgat atacgccagc gcgggcaata cgcccaaaca tacaatccac agcacatagc
     2341 ccggcgtaat caggcgcgcg ctttcggcag ccgtagtttg caagacatta ttcaacatcg
     2401 acttgttgaa atagatattg aaaaatattt cttggtaaga caccgccgca ctgataacca
     2461 atatcaacgg aatcaatacc ttatgcacga aaggcagggc aatgacgtga aaaacgaaat
     2521 tacttaaaaa aaacagcacc accggcatcg tatagaggaa gatatccgcc ccggtgccgt
     2581 taaaaggatg aagctcgaca actttggcaa aaaaggcgta attcaatacc agcgaggaat
     2641 acagggaaag gaaggcaatc agcgcggaag agccgagctt cggcctcagg ttcggtttta
     2701 tcatttggaa tgtgtcggat aagggttgga aaaggcatcc ggcatttgga atccggatta
     2761 ttgaaaaaga ttcttaatta taaggcaacg gagcaaagca gggcaagaaa acggaaggcg
     2821 acgcaggctg tcggatacac atctcggcac aaacagcatc acgcccggat tgaaaaggac
     2881 ggatagccgc cggcagcaca gttttacccc gcatcccaaa acgccgccgg agaacgccga
     2941 aacagccgat gccgtctgaa gccgcttcag acaacatcgg gacatcaacc gtaacgccgt
     3001 tggaaatcgc gcataaaatc tgccaaagcc cgcacgcctt cgagcggcat cgcattataa
     3061 atgctggcac gcataccgcc gacggtttta tagcccttaa gcaggcacaa gccctgcaat
     3121 tcggcttcca gcacaaaacg gcggtcaagc tcctcatcct ccgtttggaa cacgacattc
     3181 attttagaac gcgcattcgg acggatacgg ttgatataga aaccgccgct gccatctatc
     3241 gtctcataca aggtttgcgc cttcagccga ttgaccgctt caattttttt cacaccgccc
     3301 tgcgcctgca gccagcggaa caccagcccc gacatataaa tcgcgtaagt tgacggcgtg
     3361 ttgtacatac cgtcgcggtt gatgtgcgaa cggtagttga acacatcggg aatatcgttc
     3421 ggacaacgct cgagcaaatc ctcgcggata atgaccacgg tcgcaccggc cgggccgatg
     3481 tttttctgtg cgcctgcgta aatcagtccg tagtcggcaa catcaaactc gcgcgacaaa
     3541 atctcgctgg acatatcgca caccagcggc ggcatgcctt ctgaaaggcg cggcacttca
     3601 cggtattgca gcccgttgac cgtttcattg acggcaaaat ggacaaacgc cgaatcgggt
     3661 gcaacatccc acgtttccac aggcggcagg tcgagatagt cgaactgctc gccgccatgc
     3721 gccgccaaac ggatttccgt atcggtcaaa cggctcatct gttcataagc gatacggctc
     3781 cagttgcccg ttaccaccgc gtcggcagtg cggaaaccgt gtgccagatt catggctgcc
     3841 atattaaatt gggttgttgc tccgccctgc agaaacaata tcttatagtt gtcaggcact
     3901 ttcaaaagct gcctcaaatc ctgttccgca tgatgcagga tgctcaaaaa catttccgaa
     3961 cggtggctca tcgccatcac gggaaaaccc gtaccgttgt agtccaacat ttcctgccgc
     4021 gccgtttcca acacggcttc gggcaatacg gcagggccgg cggaaaaatt gtaaatcgga
     4081 taaagagaca tgatgcagcc ttgattctga acaataaccc gcctgatttt aggcttgcag
     4141 caggctttgt gcaaggatgg gaaatacctg tcctccgccc cgcttcatgc cgcccgaaca
     4201 cggaaaacaa catcaatata ttgatttaca aatataaaaa tcatgctagc gacaaataga
     4261 tacatttgtt ttgtcaacaa tattcacgat ttcccattac aaacctccct tacacccgct
     4321 tttttccgtc ccaaaaacac aaaataaatc aacactttca tttctccgca aaagcggtta
     4381 taatcacgcc gatttttcaa ctttgacgaa aaatggccac ggggccattt ttttattatg
     4441 tacataggga gcagcatgga tatccaaacc atcctcgaaa aaaccctgcc cggcctgggc
     4501 tacgaactgg tcgatttcga actgaccgcg caaggaacat tgcgcgtgtt catcgacaaa
     4561 gaaggcggca ttaccgtcga agactgcgca accgtcagca accacttgag ccgcgtattt
     4621 atggttgaag acatcgacta caaaaacctg gaaatttcca gccccggact cgaccgcccc
     4681 ttgaaaaaag ccgccgactt cgtgcgcttt gccggtcaga atgccaaaat caaaacccgc
     4741 ctgccgatag acggtcaaaa aaactttatc ggtaaaatcg aaggctgcga aaacgacact
     4801 gttaccgttt ccttcgacgg caaaaccgta caaatcgaat tgggcaacat cgacaaagcc
     4861 cgcctgcgcc ccgaattcaa attctaaaac acaacaatat tggagatgtt caaaatgagt
     4921 cgtgaaatgt tacagctggc agaagcactg gcaagcgaaa aaaacgttga tgccgaagtc
     4981 gtcttccaag cactggaatt cgccctgtct accgccgcca agaaaaaggc agaccgcgaa
     5041 cacatggatg tccgcgtaca aatcaaccgc gacaccggcg aataccaaac cttccgccgc
     5101 tggctgattg tcgccgatga agactatacc tatcccgatg tcgaaaaaac catcgaggaa
     5161 atccaagagg aaattcccgg cactaccatc caaatcggcg aatactacga agagcagctg
     5221 cccaacgaag gcttcggccg ccaagccgcg caaaccgcca aacaaatcat cctgcaacgc
     5281 atccgcgatg ccgagcgcga gcagaatctg aacgagtttc tcgccgtcaa agaagacatc
     5341 gtgtccggca cggtcaaacg cgtcgaacgc cacggcatca tcgtcgaagt cgttgccggc
     5401 aaactggacg cgctgattcc gcgcgaccaa atgattccgc gcgaaaactt ccgcagcggc
     5461 gaccgcatcc gcgccctctt cctgcgcgtc gaagaaatcg gcaacaccgg ccgcaaacaa
     5521 gtcatcctga gccgtacttc cggcgatttc ctcgtcaaac tgtacgccaa tgaagtacct
     5581 gaaattgcag acggcatgct tgaaatccgc gctgtcgccc gcgacccggg ccagcgtgcc
     5641 aaagtcgccg tcaaagccaa cgaccagcgc atcgatccgc aaggcacctg tatcggcgtt
     5701 cgcggttcgc gtgtcaatgc cgtcagcaac gaattgtccg gcgagcgcat cgacgttgtc
     5761 ctttggtcgc ccgagcctgc ccaattcgtc atgagcgcgc tctcacccgc cgaagtcagc
     5821 cgcatcgtca tcgacgaaga caaacacgcc gtcgatgtca tcgttgccga agaccagctc
     5881 gcgctcgcca tcggacgcgg cggtcaaaac gtgcgccttg cttccgacct gaccggctgg
     5941 cagctcaaca tcatgacttc cgccgaggca gacgaacgca atgcggcaga agatgccgcc
     6001 atccgccgcc tgtttatgga tcacttgaac gtggacgaag aaaccgccga cgtactggtt
     6061 caggaaggtt ttgcaacctt ggaagaagtc gcctatgttc ctgccgccga actgcttgcc
     6121 attgaaggat ttgacgaaga aatcgtcgat atgctccgca accgcgcccg cgatgccatc
     6181 ctgaccatgg cgattgccgc cgaagaaaaa ctgggcgaag tatccgacga tatgcgcaac
     6241 ctcgaaggcg tagatgccga tatgctccgc agccttgccg aagcaggcat taccacccgc
     6301 gacgacttgg cagagcttgc cgtggacgaa ctgattgaaa ttaccggtgt aaacgaagaa
     6361 accgcaaaag ccgtcatcct gaccgctcgc gaacactggt ttaccgaaga caaataaaag
     6421 ggggtacaga tgagtaacac aaccgtagaa caatttgccg ccgagctgaa acgccccgtc
     6481 gaagacctgt tgaaacagtt gaaagaagcc ggcgtcagca aaaacagcgg cagcgattcc
     6541 ctgacgctgg acgacaaaca gcttctgaac gcctacctga ccaagaaaaa cggcagcaac
     6601 ggcggcacca tcagcatccg ccgcaccaaa accgaagtca gcaccgttga cggcgtaaaa
     6661 gtcgaaacac gcaaacgcgg acgcactgtc aacattcctt ctgccgaaga attggcagca
     6721 caggtaaaag ccgcccaaac ccaagccgca cctgtccggc cggagcagac ggcagaagac
     6781 acggcaaaag cccgagccga agctgccgca cgtgcagaag cccgtgccaa ggcagaagcg
     6841 gaagcggcaa aactgaaagc ggcaaaagca ggcaacaaag ccaaacctgc cgcgcagaaa
     6901 cccaccgaag caaaagccga aaccgcacct gttgcggcgg aaaccaaacc cgccgaagaa
     6961 agcaaagcgg aaaaagccca agccgacaaa atgccgtcta aaaaacccgc cgagcccaaa
     7021 gaaaaagccg ccaagccgaa acacgagcga aacggcaaag gcaaagatgc caaaaaacca
     7081 gcgaaacctg ccgcacctgc cgtgccgcaa cccgtggtca gcgcagaaga acaggcgcaa
     7141 cgcgatgaag aagcacgccg tgccgccgca cttcgcgccc accaggaagc cctgttgaaa
     7201 gagaaacagg aacgccaggc acgccgcgaa gccatgaaac aacaggcaga acaacaggca
     7261 aaaaccgcac aggaagccaa aaccggcaga cagcgtcccg ccaaacctgc cgagaaaccg
     7321 caggcagccg cgccggccgt cgaaaacaag cctgtcaatc cggcaaaagc gaaaaaagaa
     7381 gaccgccgca accgcgatga cgaaggtcaa ggccgcaacg ccaaaggcaa aggcggaaaa
     7441 ggcgggcgcg accgcaacaa tgcacgcaac ggcgacgacg agcgcgtacg cggcagcaaa
     7501 aaaggcaaaa aactcaaact cgagccgaat caacacgcct tccaagcacc gaccgaaccc
     7561 gtcgttcatg aagttttggt tcccgaaacc attaccgttg ccgatttggc gcacaaaatg
     7621 gcggtcaaag gcgtggaagt ggtcaaagcc ctgatgaaga tgggcatgat ggttaccatc
     7681 aaccaatcca tcgaccaaga caccgccctg attgtggtgg aagaactcgg ccacatcggc
     7741 aaacctgccg cagccgacga ccctgaagca ttcttggacg agggcgcgga agcggtggaa
     7801 gccgaagcat tgccgcgtcc gcccgtcgtt accgtcatgg gccacgtcga ccacggcaaa
     7861 acctcgctgc tggactacat ccgccgtacc aaagtggtac agggcgaagc aggcggcatt
     7921 acccaacaca tcggtgcata ccacgttgaa accccacgcg gcgtgattac cttcttggat
     7981 actccgggtc acgaagcgtt tactgccatg cgtgcgcgcg gtgcgaaagc aaccgatatc
     8041 gtgattcttg tggtcgccgc cgacgacggt gtgatgccgc aaaccatcga agcgattgcc
     8101 cacgccaaag cggcaggcgt accgatggtg gttgccgtca acaaaatcga taaagaagcc
     8161 gccaacccag agcgtatccg ccaagagctg accgcacacg aagtcgtgcc tgacgaatgg
     8221 ggcggcgatg tacagtttat cgacgtttcc gctaaaaaag gcctgaacat cgatgcattg
     8281 ctcgaagcag tcttgctcga agccgaagtt ttggaactga ctgcccctgt cgatgcacct
     8341 gccaaaggta tcatcgttga ggcacgtttg gacaaaggcc gcggcgcggt tgccacattg
     8401 ctggttcaaa gcggtacgct gaaaaaaggc gatatgctgc tggccggtac ggcattcggc
     8461 aaaatccgcg cgatggtcga tgaaaacggc aaatccatta ccgaagccgg cccgtccatc
     8521 cccgtcgaaa tcctcggctt gtccgacgta ccgaatgcgg gtgaagacgc gatggtattg
     8581 gcggacgaga aaaaagcgcg cgaaatcgcc ctcttccgcc aaggcaaata ccgcgacgtg
     8641 cgccttgcca aacagcaggc ggcgaagctg gaaaatatgt tcaacaatat gggcgaaacc
     8701 caggcccaat ctttgtcggt catcatcaag gcagacgttc agggttctta cgaggctttg
     8761 gcgggcagcc tgaaaaaact gtccaccgac gaggtgaaag tgaacgtatt acacagcggc
     8821 gtgggcggca ttaccgaatc agatgtcaac cttgccatcg cttcgggcgc gttcattatc
     8881 ggctttaacg tgcgtgcaga tgcctcttcg cgcaaacttg ccgaaaatga aaacgtggaa
     8941 atccgctact acaacatcat ctacgatgcc atcgacgacg tgaaggcggc gatgagcggc
     9001 atgctttctc cggaagagaa agagcaagta accggtacgg tcgaaatccg tcaggtcatc
     9061 tccgtttcca aggtcggcaa cattgcaggc tgtatggtta ccgacggcgt ggtcaaacgc
     9121 gattcccatg tccgcctcat ccgcaacaac gtggtcatcc acacgggcga actggcttcg
     9181 ttgaaacgct ataaagacga cgtcaaagaa gtccgtatgg gctttgagtg cggcctgatg
     9241 ctcaaaggct acaacgaaat catggaaggc gaccaactgg aatgcttcga catcgtcgaa
     9301 gtggcacgca ccctgtgatt ttgatgcgga aaaatgccgt ctgaagcgtt cagacggcat
     9361 acggaacggg ttctgtatca tacagaaccc gttttttatc gcaaatcggc ttcagacagc
     9421 cctcctgcct tatcccgatt tgaatctgac ttgccataca aacaggcttc agacggcatt
     9481 atagtgaatt aaatttaaac cggtacagcg ttggctcgcc ttgccgtact atttgtactg
     9541 tctgcggctc gccgccttgt cctgatttaa atttaattca ctatattttc ccgacaggcg
     9601 gatttgaagt ttctccacat atccggcgcg ttcggcgcgg ctggtttcgg ggcggtgcgt
     9661 attgagcgac gaccatttcc aatgactgcg ggctttgttg agttcgggcg ggagtctggc
     9721 ggcgtcccac ggggctttgc ggctgtgcag ctcgatatcc gactgtgccg cgtgtccgcg
     9781 cgtttgcagg acgtggagca aatcgagggc gcgggcggcg agcagggtca aggtttcagg
     9841 gtcggtgtgc aaggtttggc ggccggagag tttgtcggaa atggtgcggg tattgggcag
     9901 gatgccgccc aaaaagccgc cgattgccgt acccaatccg agcgagccgc cgagtgtggc
     9961 gatgtccagc cccaagccga tgagcgcgcc ggttgccgcg cccgtgccgg tgcggatgcc
    10021 gtattgtttg agcaattcgc tgtcgaacgg gtcttggcgg aaggcttgcg gcatccagtc
    10081 gccgccgtcg atttcgctgt ggtagaaacg gtagagggca aacagccgct gctgcatctg
    10141 ccgttcgagt tggcgtattt ccgcctgcat ggtttgtagc acggtggcgg tatcctcgtt
    10201 ttcgtccact tcctgcctga aggcggcggc atcaattaaa aagtcggcga tttcgcggcg
    10261 cgcttcgccg tccagccgct gccattcgcg ccggcgcatg gctgtcaggc ggtcaagtgt
    10321 gctgcgttcg ggcaacatgg tggcgaggtt ttcccacagg cgtagttcgc cttcaaaatc
    10381 aaaggcgacg gtgtcgaacc ctgcgaaaac gtgcaggttt ctcctcgcca gcatggttgt
    10441 ccacgattcg ggaggctgtc cgccggtaaa gttgaacacg ggcataaccg gtttggcaca
    10501 ccatgaaagg atggtcaact cgtccctgta tttgtcgagg acgggttcgc gcgcgtcgat
    10561 gacgtacatt gccatatcgc tttgcaagac ttgccgtaag actttggctt cctgattgaa
    10621 atcatggtgc gcgccgtggc tgccgagaaa ctgttgcagc cgttcgatgc cgtctgaacg
    10681 attgtccgta tggttttcca gccattccag cacgccgcct gcgtcttcga gtccgggcgt
    10741 gtcgtacagg aaaaccagcg tgtctgcgcc gtcgctgatg gcggcttctt cgacatgacg
    10801 cgtggtcgat ggggcgtttc tgacttcgcc gaaaccgctg tcgcgcaaca gggtacgaag
    10861 gagcgaggtt ttgccggtgt tggtatgccc gacgacggcg agggaaaggg gttgtttgtt
    10921 catgatgttt ttgaagaatg gattttcaga cggtcttttt tcagaatggc ggcttaacag
    10981 aacatttcaa gtgagtttat tggtctttca aacgcccttc ctgcgccgcc ctgtcaggct
    11041 caagccacgc cgcgccgcat tcggccagcg cgttacgcca atgttccagc ttttccgaaa
    11101 ggtcgtctga aagcccctgt tccgccaaaa gctgcaccac cgcgccgccc tgcgccgctt
    11161 ccgaaagtcg gacgatctgc cgcaacacgc cgcggtcggg cacagtttgg gcgcgcacgc
    11221 cgataagcag ttgcgccggt ttctgcttca gctctgtctc cagcgcggca acctgttccc
    11281 gattggcggc aacgccctta tccagccatt cctgcgccag cctgccctcg aaccattcgc
    11341 cgtcctgcca ttcggtctcc agcatgaccg cccatttcgg cgcatcgttc aagacgattt
    11401 tcggcgaaac ggcggacacg gtttcccgac gcgtatccgc atcggtgatt ttgttctgcc
    11461 agcggcggat gaccgcctga taatagggtt tttccaaatc caatccgttt tcgcttgttt
    11521 tcaaaaggat tttgcatacc gcccaagcca agaggcgcgg caggatgccg tagcaggcga
    11581 tactgccgac cagcagcccc gaccaagccc gcgcatcggc aatattgccg ttcagacgac
    11641 cttcgatgac cgcccgcgca tcaggcacgg gaaaacccag tttcgcaggc agccatgcca
    11701 acatttccac cgcgcgtacc gaagcggcat tgctcaacag cgtgctttcc cagttgaacg
    11761 tatattgccg caccaaaagc agcaacaata ccgacaccag cattccgagc agtgtgcaga
    11821 gccacaggct gtgcgacgtt gcgcctattt tccaacgtac cgaaggttgc cgccactcgt
    11881 ccgcatacag ccgcaacacc gcctgattta cagggtcttt gccccgaaac cacgtcgccg
    11941 gactgctgaa aaaacgcccc actttcacgc gcaggaacaa cattgccaac catactgcca
    12001 gcatcagcgt attcatgccc aacacgcccg ccaaaaccaa aaagaaattc agaccctgat
    12061 tgtccattag aagataagta cctgaaaaac cggtaaaaaa cgcaaacgtc gccgccgcca
    12121 cccacaacca gaacgacccc gcacgcacac gttccaacgt ctcccgcagc atacggttcc
    12181 tgtcaatcat ctccgcccga cggatgattt tttcctccgt actgccgtcc acgcggcgca
    12241 aagcctccgt cgcctgcacg ggatcgccgc tgaaaataaa accgccttcg tccaaaatac
    12301 ggatcagctc aaccagtttt cgggatggat tcaacataaa atgccgtctg aaaataaaaa
    12361 acagatttta acacacgcat tttcaagaat attcacagtg taggcaaaga gtaaatctca
    12421 cacagaagca aaagtatcgg cgtaaactga ctgcctctac tttcccgaaa gattgtgcga
    12481 tgtatacagg cgaacgcttc aatacttaca gccatttgag cggtttgatt ctggcggcgg
    12541 caggtttggc gctgatgctg ctgaaaacca taggacacgg ggacggctac cgtatcttca
    12601 gcgtatcggt ttacggcatc agccttcttc tgctctattt gagttcctcg ctgtaccacg
    12661 gaattgcagc cggaaaactg aaaagcattt tgaaaaaaac cgaccactgc atgatttatg
    12721 tcctgattgc cggaagctac acaccgtttg cactggtttc tttgagaaac gggccgggct
    12781 ggacggtatt ttcactgtcc tggctgctgg cggctgcagg aatcgcacaa gaactcacca
    12841 tcggacggaa aagcgaaaaa cgactgctgt ctattgcgat ttatgtcgtc atgggttgga
    12901 tggtcttggc ggtaatgaaa tccctgacag cctcactccc gccggcagga ctggcttggc
    12961 tggcggcagg cggtatgctg tacagcgtcg gcatttactg gtttgtaaac gatgaaaaaa
    13021 tccgacacgg gcacggaatc tggcatctgt tcgtattggg cggcagcatc acccaatttg
    13081 tcagcgtgta cggttacgta atctgaatgc cgtctgaaaa gcaaaacctc ccgatcctga
    13141 agattgggag gttttctgtt tgccggacat cagcccttgt cgtggaactc gtgaaattca
    13201 tactgatagg acaaatcccg acccgctttt ttctgtgcca aataatcatc ataaatggca
    13261 cggatttcct tacgcaacaa aaacagggct atcaagttcg ggataaccat aaagccgttg
    13321 aacatatcgg acaggctcca aaccaaatcg actttgccga gcgtacccaa aacgatggca
    13381 agcagaacca atgcgcgata gatgcccaag tgtcttcccc tgaaaagaaa acggatgttg
    13441 gactcaccga aataatacca gccgataatg gtcgtcaagg cgaaaaaggt cagacacacg
    13501 gcaagcaatt gcgaaccgaa gcccggaaat gccttgttaa aggcaaattg agtaaccgcc
    13561 gcgccctgtt cgcccgaaag gttggcatcg gtcagcagga taatcagcgc agttgccgta
    13621 cataccaaaa tcgtatcgat aaatacaccg acaaatgccg ccataccttg ctgcacagga
    13681 tgcttcacat ccgcagtcgc gtgggcgtgc ggggtagaac ccatccccgc ttcgttggaa
    13741 aacagaccgc gcgccacgcc gaaacggacg gcttcgcgca taccgatacc cgccgcaccg
    13801 cccaaaacgg cttcgggatt gaaggcggcg gtaaagatgt ggttgaacat cggcacaata
    13861 tggtcggaaa attcaaacag gataacgacg gcgcacaaaa tataaacaac cgccataaac
    13921 ggcacgacaa attgggcgat attggcaata cggttcacgc cgccaatcac aaccatgccc
    13981 gcaaggacgg caagcacaat accgactgcc aaagaaggca catcaaatgc aatggtaacg
    14041 gcagaagcaa tggagtttgc ctgtgtcgca ttaccgataa agcccaatgc gataatcaac
    14101 gcaatggaaa agaaaccgga caaaaaacgc gccgcgcccc tgccgatttt cggagtcaga
    14161 ccgtgggtga tgtagaacgc cggcccgccg atgtatttgc cgtggctgac gacgcggtat
    14221 ttctgcgcca gcagtgcctc cgcaaaaatc gtggacatcc ccaaaacggc agaaacccac
    14281 atccaaaaaa tcgcgcccgg cccgcctgcg gtgatggcgg tcgccacgcc ggcgacgttg
    14341 cccgtaccga tttgcgcaga tatggcaacc gccaacgcct gaaactgcga taaagacttg
    14401 tcgtctttat cgcctttggc aaacaagccg ccgaatacgg atttgaatcc cgcgcccagc
    14461 ttggtaatct gcggcgcacc aagatacagc gtaaaaaaca ggccgatacc caaaagcgcg
    14521 taaatcagca ggtagtccca aaggaaccga ttgactgtac ccaccagaac agacaatata
    14581 ttttccataa aataaacctt atcttacaat taaaatgact gccttccaaa agacattcca
    14641 ataaggaaac acggcgagca gaccgtattt gccgcaacag atgccttaaa ttgtcaacaa
    14701 tcggggagaa gctgcgccat cataccgtaa aatatcgtta attaaaacat ttctttattt
    14761 ttaagcggaa agcggaggaa atcgctttca gacggcatcg acaacggcac ggcataaaac
    14821 aggatatttt gggtacttgc aacttatgtt aaaatgccga ccgtaaaaaa tctgacaaaa
    14881 acagattaat tatttgaaat aagaaaggaa atttatggca ggccatagca agtgggcgaa
    14941 tatccagcat aaaaaagccc gtcaggatgc caaacgcggc aaaatcttca cccgtttaat
    15001 caaagaaatc accgttgcgg cgcgtatggg cggcggcgac cccggttcaa atccgcgcct
    15061 gcgcctggct ttggaaaaag cagccgaaaa caatatgccc aaagacaatg tgcaacgcgc
    15121 catcgacaaa ggtacgggca acttggaagg cgtggaatac atcgaattgc gctacgaagg
    15181 ctacggcatc ggcggcgcgg ctttgatggt ggactgcctg accgacaaca aaacccgcac
    15241 cgttgccgac gtgcgccacg cgtttaccaa aaacggcggt aacttgggta ctgacggctg
    15301 cgtggcgttc aacttcgtgc atcagggcta tttggtattc gaacccggcg ttgacgaaga
    15361 cgcgctgatg gaagcggctt tggaagccgg tgcggaagac gtggttacca acgacgacgg
    15421 ttccatcgaa gtcattaccg cgccaaacga ttgggcgggc gtaaaatccg ctttggaggc
    15481 ggcaggttac aaatctgttg acggcgacgt tacgatgcgc gcccaaaacg aaaccgaact
    15541 ctccggcgac gatgccgtca aaatgcaaaa actgattgac gcgctggaag acttggacga
    15601 cgtgcaagac gtttacactt ccgccgtatt gaatctggac tgatacgcag cacagcagac
    15661 atacaataaa atgccgtctg aacctttcag atggcattga tttatttagc ccttgcccac
    15721 gcccaccaaa ccgtcaggac aaccgccaga aaatacgccg cgctccaaac aggcaaagca
    15781 acccctaaca gataatccgg ttcggcacaa tttccgaacc cgcgcacgac aggctcgaac
    15841 caatcaaaca aagaccagcc cttcaagcgg aacgtccacg gcgcaccgca cgaaggagcc
    15901 gtacccggcg gcagcgactg caaccacaac tgatatgccg caacagaaat acccgtaacg
    15961 gccggaatgc tgataaagac agcaccgaac aaaccgcccg cccttcttct tggtctgcac
    16021 atcaggacaa ttgccgtaca caatgcggtt gccaaaacgc ataaccgctg actgatacac
    16081 aaaacgcaag gctccatacc caaaacatac tgtgccgcca aagaaccggc aaatgcacag
    16141 accgaaacgg caaacagcag ccaaacggct tttctaaata acggggtcat tttctcaaca
    16201 caccaatcaa aataccgata tgccgatttt gctggatata tcccgagatg gcaagggacg
    16261 aatcgacacc ggctcaggtg cggacgattt cggttttccc cgatatgcac aaaacctgac
    16321 aagggacaaa acggcgattt gcccgcacaa tgcccacaaa aaaatacatc cggaggattt
    16381 gaatttcagc aaatttagcg aatcaaaagt ttatttcaat gaaatcatat gatttttttg
    16441 aataagcgga ttgatgggtt tttgaaggaa tttgttaccg gatagccatc gggcaagttt
    16501 tttgcaaaat ttgaatcggt cgggtaaatt ttcaaaaaat aattgacagc ggataagaaa
    16561 cggcggataa ttcccgccgt cgagttgctt gatgcagctt gatttttctc ctctatttct
    16621 cctttgtaga cttggcacac attcaaccgg atgtgtgcat ttttttatct ccgctttttt
    16681 tgaaatttaa ttacttttat tgtttgaaat tccattcttt aagaaattta acaagaaaaa
    16741 cgcttgcttt ttgaccggaa aagctgcata attcgttccg ttagctggtt cgagtagtca
    16801 gttaatagtt tctcctctat ttctcctttg tagacttggc acacattcta ttgaatgtgt
    16861 gcattttttt atctgaagca acaagcctct gtgcgtgatg ttgttatgtt tcatttaggt
    16921 gtcaaaccgc atagccagcc tgaaatattc aatccaaatc caaaaccgga ttttctttga
    16981 cctcctccat cacaacataa ctcctactct ccgaagcggc aggcagttgc aataggatat
    17041 tgcctagcat atcccgatag gcagacatat cgggcaaacg tactttaatc agatagtcgt
    17101 attcgcccga caccaagtgg cattccataa tttgcggaat tttcagcact tcttttttga
    17161 aatcttcgaa aatattgccc gatttggatt gcagcttcag ctcgacaaaa accaatagtg
    17221 gtttgcccaa cagatgggga ttgagatggg cgtgatagcc ggaaatataa tgttcccgct
    17281 ccaaacggcg caccctctct gtaacgggcg tggtggacaa gcctaccttc tcggcaagct
    17341 ccgtcatcgg gatgcgggca ttctgttgga ggatcttaag aatgcggaaa tcgattttat
    17401 ctagttcttt catttggatt accttgtatt tattattgat tttaacaaat agagtatata
    17461 gtggattaac aaaaaccagt acggcgttgc ctcgccttgc cgtactattt gtactgtctg
    17521 cggcttcgtc gccttgtcct gatttttgtt aatccactat atatttggga aagcgattat
    17581 atcaggaaaa gcaaaccgcc ttcctacctg aaaactgctg cttcggcttg aagacacaag
    17641 ggtctttaat attttaaaag ccttgccgtt ggattataat tccctaattg atttcttaat
    17701 tttgctaata aacacttgct tggtaaggaa tgaatttatg cgccctttga acgtgcagat
    17761 caggttgggc aaccttaggc acaattatcg gattttaaag gaaatgcacg gaggcaagct
    17821 gttggcggta gtgaaggccg acgcatacgg acacggtgcg gtcagatgtg ctttcgcgct
    17881 ggcagacttg gcagacggct ttgccgtggc gacaatcgat gaaggaatca ggctgcggga
    17941 gagcggcatt acccatccga ttgtcctttt ggaaggcgta tttgaagcat cagagtacga
    18001 agcggtcgaa caatactcgc tctggccggc agtcggaaac caatggcaac ttgaggcttt
    18061 gctttcccgc cattggaaaa aacctgtcaa ggtctggttg aaaatggatt cgggaatgca
    18121 ccgtaccgga tttttccctc atgattacgc ttcggcatat gcggcattga aacagtcgga
    18181 atatgtggac agtattgtca aattctcgca tttctcctgt gcggacgaac ccgaaagcgg
    18241 tatgacggaa atacagatgg aagcattcga tttgggtacg gaagggctgg aaggcgaaga
    18301 aagccttgcc aattcggcgg ctattttgaa tgttcccgaa gcacgcaggg attgggggcg
    18361 cgcgggcttg gcgttatacg gcatttcccc gttcggaggc agcgatgaca ggctgaaacc
    18421 cgtgatgagg ctttcaaccc gtatttttgg cgaacgcgtt ttacagccgc actcccctat
    18481 cggttatggc gcaacatttt ataccagcaa atctacgcgc gtcggtctga ttgcctgcgg
    18541 ttatgcggac ggttatccgc gccgcgctcc aagcaattcc cccgtcgccg tcgacggtaa
    18601 attgacccgg gtcatcggca gggtctctat ggatatgatg accatcgagc tggacgcttc
    18661 gcaagaaggt ttgggacacg aggtcgaact gtggggcgat acggtcaaca tcaatactgt
    18721 tgccgaagcg gccggaacca tcccttacga attgatgtgc aatatcaaac gtgcaaaatt
    18781 cacttatatc gagtaatcga gtccaaacaa aaatgccgtc tgaagccttt cagacggcat
    18841 ttccccatca aaaccgcaat cagtttttca ttgattgaac cggagccggg attctgccgc
    18901 cccgtttgac gaacacttcg cacgaacctt ctttgaccgg cattacaggc gcgtagccta
    18961 acaggccgcc gaactcgacg ctgtcgccga cggttttacc ggttaccgga ataatgcgca
    19021 cggcagtggt tttgctgttg atcatgccga tggcggcttc gtcggcaatg atgccggaaa
    19081 tggtgtgcgc gggtgtgtcg ccgggaacgg caatcatatc caagccgacc gaacaaacgg
    19141 cggtcatcgc ttcgagttta tccaacgtca gcacgcctgc ttcggcggcg gcaatcatac
    19201 cttcgtcttc ggaaacgggg ataaacgcgc cactcaaacc gccaaccgcg ctcgaagcca
    19261 tcatgccgcc ctttttcacg gcatcgttca gcaatgccaa agctgctgtt gtgccgtgcg
    19321 taccgcagac gctcaaaccc atttcttcaa gaatgcgcgc caccgagtcg ccgacggcag
    19381 gggtcggtgc cagcgacaag tcgagaatac caaacgggat attcagcatt tttgaggctt
    19441 cgcggccgat gagttcgccc acgcgggtaa ttttgaaggc ggttttcttc acaacttcgg
    19501 caacttcggt caatgtcgtt gcatccgaat tttccaacgc ggcttttacg acacctgggc
    19561 cggatacgcc gacattaatc acagcatccg cttcgcccga tccgtgaaac gcacccgcca
    19621 taaacggatt gtcttccacc gcattgcaga acacgacgat tttcgcgcag ccgaaacctt
    19681 cgggcgtaat ttcagccgtg cgtttgatgg tttcgcctgc cagcttgacc gcatccatat
    19741 tgataccggc gcgcgtactg ccgacattga tggagctgca cacgatgtcg gtggtcttca
    19801 tcgcttcggg aatggaacgg attaacacct cgtctgaagg cgacatgcct ttttgcacca
    19861 acgcggaaaa gccgccgata aaggacacgc cgatggcttt ggcagcctta tccaaagttt
    19921 gcgccacgct gacataggaa tcggcatggg tagccgccgc gatttgggca atcggcgtaa
    19981 cggaaatgcg ctgattcaca atcggcacgc cgtatttggc agacagatat tttgccgtcg
    20041 ccaccaagtc tttgccgacc gtggtaattt tgttgtaaat gttttggttc aacacattga
    20101 tatcgctgct gatgcagtcg tgcagatcaa tgccgatggt aatggtgcgg acatcaaaat
    20161 tctggtcggc aaccattttg acggtttcta aaatttcgcc ggattggata ctcatcacat
    20221 tcctccgact caaatgcggt gcatcgcttg gaagatttct tcattttgca tacggatatc
    20281 aagcgcgagt tttttgctct cttccgcaaa caaatccaaa acctcctgcc gagatttggg
    20341 gcatttcgag gtatccacca agataatcat ggtaaaaaaa tcatccatca gctgttggct
    20401 gatattgagg atgttgattc ggttttccgc caaaattttg gaaacatcgt acacgatgcc
    20461 gacgcggtct ttaccgatga cggtgatgac tgaattgttc acaggcttac tccttgcaga
    20521 tatccgttaa agtccgaaat tataccaccg ttggattttg aagaaatatt gtcaacaata
    20581 tatacataca aaatgccgtc tgaaactatt tcagacagca tcaagattca gggttcgatt
    20641 aaataaccat ccttatccca ctgggttttc ctgaccaact tgtcatcctg ataaacagct
    20701 tcactctttt tagaaccatc ttcataccac tctaagacta ctccattacg tttatgatga
    20761 tggatagaca gttccgagag taatcgaccg ctttcatccc atgtcagaat cttggccggc
    20821 tcatcattga ccataaccat ttccgttttg atattgccat cagcatacca ttgtttccat
    20881 acgccgtttg ccttattttg tttaaactgg atttcgcttt ccttgctgcc attacggtaa
    20941 tagcggtacc ccgtaccttc actcaaacca tttttataag gcataaccgc agatttttta
    21001 ccgttcggat accagttgac ccactcaccg tccggcttac ccttgctgaa gccccccgcc
    21061 atttttttct gaccattaaa atgccacaaa atcaacatac cgttttgcag ggtaggcaca
    21121 aaagatttga tttgcgttga agcaacgata taaggttcgg aatatttctt catcgacgga
    21181 taataaaaat cctgcgcgta cgcaataccc tccgccacac tatattgcct gatataagcg
    21241 gcagaagaca tcgtcgccgt cagtttcccg ttctgattaa aataaacaga ataggtctgt
    21301 gccgataaag aagccgaaaa acccaacagg acaattgaaa atacaatccg agataatttt
    21361 ttcattgcaa tagcgatata aaaacaaggc tgtgttttag taatctgttg atttcaatta
    21421 tttgcaaggg aaaagacaat tattttccgg ttaggaataa acctattcta ctgaatatat
    21481 tgaagccaag tacgcctatc aacactatat taaaacactg ccaaaaacaa ttaacttata
    21541 aacaatatgg taaggatttc tctgccaagc atcaaacccg agacaacgta tcgtaaaaat
    21601 gccgtctgaa aacaaatcgt cttcagacgg catttcccct tcaactcact cttcacccaa
    21661 taactgctcg cgcgtcaaga ggaaaacaaa accgtcgccc ccgctggttt ccaaccaagt
    21721 aaaaggcaac tccggatacg ctgcttccaa tacatccctg ttatgcccga tttccaccag
    21781 caatacacct ttgggattca gaaactttgc cgcattcaga agaatctgcc tggtggcatc
    21841 caacccgtcc gccccgctgc ccaatgccaa ttccggttcg tgcaaatact cttcaggcaa
    21901 taactcaacc gattccgcat ccacataagg cggattggaa acaatcaaat cataagtgcc
    21961 ttccaatcct tcaaacaaat ccgtatgaat aagccggatg cgttcttcca aaccataatc
    22021 ttcgacatta atccctgcca cttccaaagc atccaagctc acatcaaccg catcaatttg
    22081 ggcatcagga taatgatgcg ccatctgaat ggcaaggcaa ccgcttccgg tgcaaagatc
    22141 caaagcatta tgcaccaact catcgtattc tatccaagga cgaagtccgt cacccaacaa
    22201 ttcataaata aaagaacgag gtatgattac gcgctcatcc acatagaaat caaactctcc
    22261 ctgccatgcc tggtgtgtca aataagcggc tggaatgtgt tcgacagcac gacgctcaat
    22321 aaccgtcagc acttcctctt tttcagcttc caagagtttt gcatcaagat atggggcaag
    22381 catatccaaa ggcaaattca aagtatgcag aatcaaataa gctgcttcat catgcgcatt
    22441 atccgttcca tgaccaaaaa agagccctgc ctcattaaaa cggctgactg caaaacgtaa
    22501 aacatcgcgg atagtcgtca attcttgtgc tgcctgatta aacataatat gaaccattct
    22561 gcgtatagat acttttaatt ataacagaaa caacaagcaa accttttcat atcgccaaat
    22621 aaccacccaa tctacccata caactacata aatgcccgcg cgaaaaccat cgcccgaacg
    22681 gaaacgacaa tggccgacgg tatgggcaac ctgattggct gggaaaaaac ggggcttgtt
    22741 gccggtaagc agtggataac cgcaaaagac gacaaggtgt ccgatgtctg caatgccaac
    22801 ggcgagatgg gcgtaatcgg gctttacgag cctttctcac acggcgcatt gacgataccc
    22861 ggtcatccga actgccgatg cgaggttgtt tccgtatcgg gtggcgaatt gggggaattt
    22921 gccgaaaaaa aggagcttcg taaagcggct atgcagtatg cgcgggataa ctttatcggc
    22981 aaaagctatg tcaatgaaaa cagcgggcat gaactgaagg taacttggca aggtgtgaaa
    23041 cacgctgcgt caaaggcaaa tcaggcggaa ttatccatca tgacaaaact tgatgactta
    23101 ttgcgctacg caaaatatga gggttcttat tcggatagga aaggtcatcc taatattatt
    23161 gcagcacata agtatcgtgc cgttgccaag gttgggaatg agtctttaaa tatcggtgtg
    23221 attgtaaggg aatttccaga cgaccataaa cattacgacc atttcatctt gaaggatgaa
    23281 taaagccctt ttgcagtgtc gttctggagc ggatagcgtt aaggcaagta cacttccagc
    23341 cttgaaaaag ggctttaaat tcagcatgcc atttatacag gcaggagtaa acccatgaca
    23401 aagttatacg cagaaatcgc caagatggag acgcaggacg acgacacggt caaggtttgg
    23461 ggttacgctt caagcgagga aatcgattcg gacggcgaag tcatcgcgac ggcagctatg
    23521 aaggcggcga ttcccgatta tatgaagttt ggcgaggggc gcgagatgca cggctcaaac
    23581 gctgcgggaa cggcaattga aatcaacgtt gaagacgacg gcataacctt tttcggtgct
    23641 catatcatcg accccgttgt cgtggcgaaa gtcaaaacag gcgtttacaa aggcttttcc
    23701 atcggcggca gcgttaccgc ccgcgatgat ttgaacaagt cccaaatcac gggcttgaag
    23761 ctgacggaaa tcagccttgt cgaccgccct gccaatcccg atgcggtgtt tacctgcttt
    23821 aaggcggaca aaggtgcgga agcggtaaac aacgatacag aacataatgc tacatattt
//
LOCUS       DAXISH010000029        22575 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.029, whole genome shotgun sequence.
ACCESSION   DAXISH010000029 DAXISH010000000
VERSION     DAXISH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 22575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22575
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.029"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(231..1127)
                     /gene="argB"
                     /locus_tag="ACFOV4_001127"
     CDS             complement(231..1127)
                     /gene="argB"
                     /locus_tag="ACFOV4_001127"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HFC7619150.1"
                     /translation="MESENIISAADKARILAEALPYIRRFSGSVAVIKYGGNAMTEPA
                     LKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKVGKKGEFVQGMRVTDKEAMDIVE
                     MVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVES
                     IDTGLVKGLIERGCIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAG
                     VMDKTGNLLTKLTPKRIDELIADGTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNA
                     LLLEIFTDAGIGSMILGGGEDA"
     gene            1297..2427
                     /locus_tag="ACFOV4_001128"
     CDS             1297..2427
                     /locus_tag="ACFOV4_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M14-type cytosolic carboxypeptidase"
                     /protein_id="HFC7619151.1"
                     /translation="MIKISTRFDAGSVVVKDLTDPSNIRLALRPDNASDFAQWFYFRL
                     QGAAYQNCIMHFENAAEAAYPKGWEGYQACASYDRRNWFRVPTSYENGVLTVNHTPLS
                     NSVYYAYFEPYSEEQHLNLLGDAQGSGLCRIDDLGSTVQGRDINLLTIGNQVESDLKI
                     WITARQHPGETMAEWFVEGLLGRLLDHQDATARTLLDRATFYIVPNMNPDGSALGNLR
                     TNAAGANLNREWENPTLEKSPEVFFVREKMLETGVDLFLDIHGDEGLPFIFVAGTEGV
                     PNYNPRISALETQFKTALLNASPDFQDEYGYEKDAPGQANMTLATNWVGNRFNCLAYT
                     LEMPFKDNANLPDDDFGWNGQRSLRLGEAALSAILNIIGDLR"
     gene            2498..3349
                     /gene="lgt"
                     /locus_tag="ACFOV4_001129"
     CDS             2498..3349
                     /gene="lgt"
                     /locus_tag="ACFOV4_001129"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFC7619152.1"
                     /translation="MIIHPQFDPVLISIGPLAVRWYALSYILGFILFTFLGRRRIAQG
                     LSVFTKESLDDFLTWGILGVIFGGRLGYVLFYKFSDYLAHPLDIFKVWEGGMSFHGGF
                     LGVVIAIWLFGRKHGIGFLKLMDTVAPLVPLGLASGRIGNFINGELWGRVTDINAFWA
                     MGFPQARYEDLEAAAHNPLWAEWLQQYGMLPRHPSQLYQFALEGICLFAVVWLFSKKQ
                     RPTGQVASLFLGGYGIFRFIAEFARQPDDYLGLLTLGLSMGQWLSVPMIVLGIVGFVR
                     FGMKKQH"
     gene            complement(3432..4094)
                     /locus_tag="ACFOV4_001130"
     CDS             complement(3432..4094)
                     /locus_tag="ACFOV4_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein"
                     /protein_id="HFC7619153.1"
                     /translation="MDSRKFTEASKRRLSELLDAKSEQGNTMRCDEVQGFMTALLSGP
                     DKLTPLDWLPEVLGDESQFTAAERSEIERLVLAMAMETTAAMSDKKLPDLWLYENEDG
                     GSDFYTWCNAYLYGLDIVPTDWFEAVDDEAFEELFYPIMALGGIYDEEDNGTIRLQFT
                     EGELAELESELPYALADIYRYWQAVINKPQTVRREGEKTGRNDPCPCGSGRKYKACCG
                     KN"
     gene            complement(4189..5982)
                     /locus_tag="ACFOV4_001131"
     CDS             complement(4189..5982)
                     /locus_tag="ACFOV4_001131"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HFC7619154.1"
                     /translation="MQLDIDRLVAYFGGVNALAEALKQHDPENAATTAAIYKWRTRGS
                     LPLAQLQKLTALAEAQGRSLDLNAFLQKNESLERTEMTQTNRVIIFDTTLRDGEQSPG
                     AAMTKEEKIRVARQLEKLGVDIIEAGFAAASPGDFEAVNAIAKTITKSTVCSLSRAIE
                     RDIRQAGEAVAPAPKKRIHTFIATSPIHMEYKLKMKPKQVIEAAVKAVKIAREYTDDV
                     EFSCEDALRSEIDFLAEICGAVIEAGATTINIPDTVGYSIPYKTEEFFRELIAKTPNG
                     GKVVWSAHCHNDLGLAVANSLAALKGGARQVECTVNGLGERAGNASVEEIVMALKVRH
                     DLFGLETGIDTTQIVPSSKLVSTITGYPVQPNKAIVGANAFSHESGIHQDGVLKHRET
                     YEIMSAESVGWATNRLSLGKLSGRNAFKTKLADLGIELESEEALNAAFARFKELADKK
                     REIFDEDLHALVSDEMGSMNAESYKFISQKISTETGEEPRADIVFSIKGEEKRASATG
                     SGPVDAIFKAIESVAQSGAALQIYSVNAVTQGTESQGETSVRLARGNRVVNGQGADTD
                     VLVATAKAYLSALSKLEFSAAKPKAQGSGTI"
     gene            6228..7337
                     /gene="proB"
                     /locus_tag="ACFOV4_001132"
     CDS             6228..7337
                     /gene="proB"
                     /locus_tag="ACFOV4_001132"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFC7619155.1"
                     /translation="MKYKRIVFKVGTSSITHSDGSLSRGKIQTITRQLAALHHAGHEL
                     VLVSSGAVAAGFGALGFKKRPVKIADKQASAAVGQGLLMEEYTANLSSDGIVSAQILL
                     SRADFADKRRYQNAGSALSVLLQRRAVPIINENDTVSVEELKIGDNDTLSAQVAAMIQ
                     ADLLVLLTDIDGLYTGNPNSNPDAVRLDKIEHINHEIIEMAGGSGSANGTGGMLTKIK
                     AATIATESGVPVYICSSLKPDALAEAADNQADGSFFVPRAKGLRTQKQWLAFYSESRG
                     GVYVDEGAEHALSEQGKSLLMSGIAGIEGHFSRMDTVTVYSKATKQPLGKGRVLFGSA
                     AAEDLLKSRKAKGVFIHRDDWISITPEIRLLLTEF"
     gene            7350..8612
                     /locus_tag="ACFOV4_001133"
     CDS             7350..8612
                     /locus_tag="ACFOV4_001133"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFC7619156.1"
                     /translation="MSNTQKQLALAKAAKKSVNTADTEEKNRALFAMADSLEAAAADI
                     LAANRQDLEAAAGNIPESMTDRLLLDGKRICAMADGIRAVAALPDPVGEILETSTLPN
                     GLEIVKKRVAMGVIGIIYESRPNVTSDAAALALKSGSAVVLRSGKDAFQSARAIVAAL
                     KTGLAQTRIDPDALQLIEDTGREGSYEMMRAKDYLDLLIPRGGAGLIRAVVENAVVPV
                     IETGTGIVHIYVDKDADLEKAIRIVRNAKTSRPSVCNSMEVLLVHEDIAADFLPKLER
                     LLVRDRIEAGLPPVRFRLDPQAARHIGGEAAGADDFDTEFLDYILAVKTVASVEEAVG
                     HIETHGTHHSDGIVTENRHAADYFTTHIDSAAVYVNASTRFTDGGEFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYIVQGTGQVRE"
     gene            complement(8837..11869)
                     /locus_tag="ACFOV4_001134"
     CDS             complement(8837..11869)
                     /locus_tag="ACFOV4_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015616 - DNA translocase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFC7619157.1"
                     /translation="MFWIVMIVILLLALAGLFFVRAQSEREWMREVSAWQEKKGEKQA
                     ELPEIKDGMPDFPELALMLFHAVKTAVYWLFVGVVRFCRNYLAHESEPDRPVPPASAN
                     RADVPNASDGYSDSGNGTEEAETEAAEAAEEEAADTEDIATAVIDNRRIPFDRSIAEG
                     LMPSESEISPVRPVFKEITLEEATRALNGAALRETKKRYIDAFEKNETAVPKVRVSDT
                     PMEGLQIIGLDDPVLQRTYSRMFDADKEAFSESADYGFEPYFEKQHPSAFSAVKAENA
                     RNAPFRRHAGQAEAKSPDVSQGQSVSDGTAVRDACRRVSVNLKEPNKATVSAEARISR
                     LIPESRTVVGKRDVEMPSETENVFTETVSSVGYGGPVYDEAADIYIEEPAAPDAWVVE
                     PPEVPKVPMPAIDIPPPPPVSEIYNRTYEPPAEFEQAQRSRIAETDHLADDVLNGGWQ
                     EETAAIADDGSEGAAERSSGQYLSETEAFGHDSQAVCPFENVPSERPSCRVSDTEADE
                     GAFQSEETGAVSEHLPTTDLLLPPLFNPEATQTEEELLENSITIEEKLAEFKVKVKVV
                     DSYSGPVITRYEIEPDVGVRGNSVLNLEKDLARSLGVASIRVVETIPGKTCMGLELPN
                     PKRQMIRLSEIFNSPEFAESKSKLTLALGQDITGQPVVTDLGKAPHLLVAGTTGSGKS
                     VGVNAMILSMLFKAAPEDVRMIMIDPKMLELSIYEGIPHLLAPVVTDMKLAANALNWC
                     VNEMEKRYRLMSFMGVRNLAGFNQKIAEAAARGEKIGNPFSLTPDDPEPLEKLPFIVV
                     VVDEFADLMMTAGKKIEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRI
                     AFQVSSKIDSRTILDQMGAENLLGQGDMLFLPPGTAYPQRVHGAFASDEEVHRVVEYL
                     KQFGEPDYVDDILSGSGSEELPGIGRSGDDETDPMYDEAVSVVLKTRKASISGVQRAL
                     RIGYNRAARLIDQMEAEGIVSAPEHNGNRTILVPLDNA"
     gene            12034..12714
                     /locus_tag="ACFOV4_001135"
     CDS             12034..12714
                     /locus_tag="ACFOV4_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HFC7619158.1"
                     /translation="MIFQTVWFSDVVLSVSWIVLILILAASAPSAFRSLARYRSALPL
                     CTVIFSAAWCLNASAGGGQLAQMNYHLLAVNLVALMVGTSAAFWLAALLMLPYCLLFA
                     GSVGAYPPNALVLILPALAVNRLSRMLVNRLPPNIFIFIFVNGFLASAAGILLTGLVL
                     TGILDAANAFPSEILWTTALPVFILLAWAEAFLSGISTAIFVALKPHWINTFDDNRYL
                     KSDRGIWR"
     gene            12743..13102
                     /locus_tag="ACFOV4_001136"
     CDS             12743..13102
                     /locus_tag="ACFOV4_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HFC7619159.1"
                     /translation="MLSNIIPLSIGAALGATARWLLNLAVPAAMSPATGNLFANWTGA
                     LLIGIFAETINHPQWKLLLITGFLGSLTTLSGFSLETVTLLQSNRPASALANIFLHTA
                     GSLLLTWLGLKIGAAVK"
     gene            complement(13758..14294)
                     /locus_tag="ACFOV4_001137"
     CDS             complement(13758..14294)
                     /locus_tag="ACFOV4_001137"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFC7619160.1"
                     /translation="MDLREVKLGGETIYEGGFVSISRDKVRLPNGNEGQRIVIRHPGA
                     ACVLAVTDEEKVVLVRQWRYAANQATLELPAGKLDVAGEDMAACALRELAEETPYTTD
                     SVRLLYSFYTAVGFCNEKMYLFEAEGVRLGSTLANDEDEITETVLMSKEEVRQALAND
                     EIKDGKTLIGLQYWLMKD"
     gene            complement(14328..14684)
                     /gene="folB"
                     /locus_tag="ACFOV4_001138"
     CDS             complement(14328..14684)
                     /gene="folB"
                     /locus_tag="ACFOV4_001138"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HFC7619161.1"
                     /translation="MDKIFLHGIKADTLIGVYGWERERLQTLIVDLDIGVPEKAGSDD
                     DIANTVHYAEVCETLRRHLKEQDFLLLEALAEYIADLVLGYFGAVWVRVKIVKPGILE
                     GVREVGVEIERGKRED"
     gene            14740..15342
                     /gene="plsY"
                     /locus_tag="ACFOV4_001139"
     CDS             14740..15342
                     /gene="plsY"
                     /locus_tag="ACFOV4_001139"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFC7619162.1"
                     /translation="MFNIPAVAVSYLIGSLSFAVIVSKYYGMDDPRTYGSGNPGATNV
                     LRSGKKKAAVLTLLGDAAKGLVAVLLARVLQEPLGLSDSAIAAVALAALVGHMWPVFF
                     GFKGGKGVATALGVLLALSPATALVCALIWLVMAFGFKVSSLAALTATIAAPLAALFF
                     MPHTSWIFATLAIAILVLLRHKSNILNLIKGKESKIGGSR"
     gene            15419..16264
                     /locus_tag="ACFOV4_001140"
                     /pseudo
     CDS             15419..16264
                     /locus_tag="ACFOV4_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221597.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008988 - rRNA
                     (adenine-N6-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase
                     RlmJ"
     gene            complement(16362..16634)
                     /locus_tag="ACFOV4_001141"
     CDS             complement(16362..16634)
                     /locus_tag="ACFOV4_001141"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619163.1"
                     /translation="MPSERRQIAAGRSFGAFRQISRGIVVEKNGAGQVGTRQADEGIF
                     ILIVDKFKPVQRCLALAQRERFSKVLKHQVNRFRTICTVCGFVALS"
     gene            16659..17633
                     /locus_tag="ACFOV4_001142"
     CDS             16659..17633
                     /locus_tag="ACFOV4_001142"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HFC7619164.1"
                     /translation="MDTLTRFLPEHLQQNQLPEALCGVLLSVVSACTEINAKVRLGAL
                     AGVLGMAGTGNIQGEDQKKLDVIANNIMIDTLKANPAVAGLASEEEDSFVSAGENGRY
                     LVLFDPLDGSSNIDVNISVGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQ
                     LVFTFGHGVYMFTLNAENEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELL
                     AGETGTRGKNYNMRWVASMVAEIHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMS
                     LILEQAGASASNAYQAMLDIQPENLHQRVAVIMGSSEEVDYLNRLHSK"
     gene            complement(17792..18010)
                     /locus_tag="ACFOV4_001143"
     CDS             complement(17792..18010)
                     /locus_tag="ACFOV4_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HFC7619165.1"
                     /translation="MFPEYRDLISKLKQENSRFARLFDEHNELDDKITGLVNNPVTSG
                     AETIDELKKAKLKLKDELYAILQKAAGK"
     gene            18354..18616
                     /locus_tag="ACFOV4_001144"
                     /pseudo
     CDS             18354..18616
                     /locus_tag="ACFOV4_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007116440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
     gene            18784..20559
                     /gene="ggt"
                     /locus_tag="ACFOV4_001145"
     CDS             18784..20559
                     /gene="ggt"
                     /locus_tag="ACFOV4_001145"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HFC7619166.1"
                     /translation="MAKTYLLTALIMSMTISGCQVIHANQGKVNTHSAVITGADAHTP
                     EHATGLIEQKQVIASDFMVASANPLATQAGYDILKQGGSAADAMVAVQTTLSLVEPQS
                     SGLGGGAFVLYWDNTAKTLTTFDGRETAPMRATPELFLDKDGQPLKFMEAVVGGRSVG
                     TPAIPKLMETIHQRYGVLPWGKLFDTPIRLAKQGFEVSPRLAISVEQNQQHLARYPKT
                     AAYFLPNGVPLQAGSLLKNLEFADSVQALAAQGAKALHTGKYAQNIVSVVQNAKDNPG
                     QLSLQDLSDYQVVERPPVCVTYRIYEVCGMGAPSSGGIAVGQILGILNEFSPNQVGYD
                     AEGLRLLGDASRLAFADRDVYLGDPDFVPVPIRQLISKDYLKHRSQLLEQSDKALPSV
                     SAGDFIHEWVSSQAIELPSTSHISIVDKAGNVLSMTTSIENAFGSTLMANGYLLNNEL
                     TDFSFEPIKQGKQVANRVEPGKRPRSSMAPTIVFKAGKPYMAIGSPGGSRIIGYVAKT
                     IVAHSDWNMDIQDAISAPNLLNRFGNYELETGTTALQWQQALNDLGYKTDVRELNSGV
                     QAIIIEPSRLVGGADPRREGRVMGD"
     gene            20622..20885
                     /locus_tag="ACFOV4_001146"
     CDS             20622..20885
                     /locus_tag="ACFOV4_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619167.1"
                     /translation="MSNQTKIQAIKQASEQIFAICETPNTALQAIHLILRHGGAGELS
                     WQVVYQRVMADKDVVGAGYLIDFAQTAENLPFDVLPLGSLVLT"
     gene            21040..22290
                     /gene="glyA"
                     /locus_tag="ACFOV4_001147"
     CDS             21040..22290
                     /gene="glyA"
                     /locus_tag="ACFOV4_001147"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFC7619168.1"
                     /translation="MFSKSVTLAQYDPDLAAAIAQEDQRQQDHVELIASENYVSCAVM
                     EAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRVKKLFGAQYANVQPHSGSQAN
                     QAVYASVLKPGDTILGMSLAHGGHLTHGASVNISGKLYNAVTYGLDENEVLDYAEVER
                     LALEHKPKMIVAGASAYALQIDWAKFREIADKVGAYLFVDMAHYAGLIAGGEYPNPVP
                     FCDFVTTTTHKTLRGPRGGVILCRDNTHEKALNSAIFPSLQGGPLMHVIAAKAVAFKE
                     ALQPEFKQYAKQVKINAAAMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAA
                     LGKAHITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNEADARVLANLVADVLSNPE
                     DEANLENVRKQITALCDKYTVYGA"
     gene            22418..>22575
                     /locus_tag="ACFOV4_001148"
     CDS             22418..>22575
                     /locus_tag="ACFOV4_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC7619169.1"
                     /translation="MSTFFQQTAQAMIAKHIDRFPLLKLDQVIDWQPIEQYLNRQRTR
                     YLRDHRGHP"
BASE COUNT         5390 a         6285 c         5510 g         5390 t
ORIGIN      
        1 gacaaggcga ccaagccgca gacagtacaa atagtacgga accgattcac ttggtgcttc
       61 agcaccttag agaatcgttc tctttgagct aaggcgaggc aacgccgtac tggtttttgt
      121 taatccacta tattttttca ggaatgacgg tttggaaatt gcccgaaacc ccaaaaacag
      181 aaaccggaca aacgggtttt ccgccaaagc cggcattttc cgactttgct tcaggcatct
      241 tccccaccgc ccaaaatcat cgaaccgata ccggcatcgg taaagatttc cagcaaaagc
      301 gcgttgggca ccctgccgtc gatgatgtgc gtggctttca cgccgttgac ggcggcttcg
      361 accgcggaag cgattttcgg cagcataccg ccatacagcg tgccgtcggc aatcagttca
      421 tcaatccgtt tcggcgtgag tttggtcagc agattgcccg ttttgtccat cacaccggcg
      481 atattcgtca tcatcaaaag tttttcggcg ttcaattctt ccgccaattt gcctgccacc
      541 aaatcggcgt tgatgttgaa cgcttcgcct ttttcaccta cgccgacggg ggcgacgacg
      601 ggaatgcagc cacgttctat cagcccttta accaaaccgg tatcgatgct ttccaccgta
      661 ccgacctgtc cgatgtccac gccattctgt tcgggcgtat caatcaaaag tttcttcgcc
      721 ttaatgaaat ggtcgtcgcg tccgcttacg ccgaccgcgt gtccgccata tgtgttaatc
      781 atcgacacga tttctttatt gacatgcccg cccaacacca tttcgacaat atccatcgcc
      841 tctttgtcgg taacgcgcat tccttggaca aactcaccct ttttgccgac tttttcaagc
      901 atcgcattga tctgcggccc gccgccgtga acgatgacgg gatgaatgcc gaccagcttc
      961 agcagcacga catcgcgggc aaacccttct ttcaaggcag gttcggtcat cgcgttgccg
     1021 ccgtatttga tgacggcgac cgaaccggaa aaccggcgga tgtaaggcag cgcttcggca
     1081 aggatacgcg ccttgtcggc ggcggaaata atgttttcag actccataac ggctccctat
     1141 tgttaacaat ttcggcttat gttaacgcca aacgccgtct gaaacaatct tcagacggca
     1201 tccggcagac tttcgggcag gttgaagcct tgcgatacgg gcggtaaaat cgcggtttat
     1261 ccggttcgag aaaccggcga cagcaaggac tttcccatga ttaaaatcag cacccgcttc
     1321 gatgccggct cggtcgtcgt caaagacctg accgatcctt ccaacatccg cctcgccctg
     1381 cgtcccgaca acgcctccga ttttgcacaa tggttctact tccggctgca aggcgcggca
     1441 tatcaaaact gcatcatgca ttttgaaaac gcggcagaag ccgcctaccc gaaaggctgg
     1501 gaaggctatc aggcgtgtgc ctcatacgac cgccgcaact ggttccgcgt accgacttcc
     1561 tacgaaaacg gcgtactgac cgtcaaccat accccgctgt ccaatagcgt gtactacgcc
     1621 tatttcgaac cctattccga agaacagcac ctcaacctcc tcggcgacgc gcaaggcagc
     1681 ggcctgtgcc gcatcgacga cttgggcagc accgtgcaag ggcgcgacat caatctgctg
     1741 accataggca atcaggtcga aagcgatttg aaaatctgga ttaccgcccg ccagcatcca
     1801 ggcgaaacca tggcggaatg gtttgtcgaa ggactgctcg gcaggctgct cgaccatcag
     1861 gatgcaaccg cgcgcaccct gctcgatcgc gccacgttct atatcgtccc caacatgaac
     1921 cccgacggtt cggcactggg caaccttcgc accaacgccg ccggtgcgaa cctcaaccgc
     1981 gaatgggaaa atccgacttt ggaaaaaagc cccgaagtgt tcttcgtgcg cgaaaaaatg
     2041 ctggaaaccg gcgtggattt gttcttggac atccacggcg acgaagggct gccctttatc
     2101 tttgttgcag gaactgaagg cgtgccaaac tacaatccgc gcatttccgc gttggaaaca
     2161 cagttcaaaa ccgccctttt gaacgccagc cccgatttcc aagacgaata cggttacgaa
     2221 aaagatgcgc ccggtcaggc aaacatgacc ttggcaacaa actgggtcgg caaccgtttc
     2281 aactgccttg cctatacgtt ggaaatgccc tttaaagaca atgccaacct gcccgacgac
     2341 gatttcggat ggaacggtca acggtcgttg cgcttgggcg aagccgcgtt gtccgccatc
     2401 ctcaacatca tcggcgattt gcgctgaaac ccttattgca gaaatgccgt ctgaagcatc
     2461 atgcctttca gacggcattt gaaaacgaaa gcctgttatg attatccatc cccaattcga
     2521 tcccgtcctc atcagtatcg gcccgcttgc cgtccgctgg tatgccctaa gctacatcct
     2581 cggatttatt ctttttacct ttctcggcag aaggcgcatc gcgcaaggct tgtccgtttt
     2641 taccaaagaa tcgcttgacg acttcctcac ttggggcatt ttgggcgtaa tttttggtgg
     2701 gcgtttgggt tacgtcctgt tttacaagtt ttccgactac ctcgcccatc cgcttgatat
     2761 tttcaaggta tgggaaggcg gaatgtcgtt ccacggcggc tttttgggtg tagttattgc
     2821 catatggttg ttcggccgca aacacggcat cggcttcctc aaactgatgg acacggtcgc
     2881 accgctcgtt ccgctgggtc tcgcttcggg acgtatcggc aacttcatca acggcgaact
     2941 ttggggacgc gttaccgaca tcaacgcatt ttgggcaatg ggcttcccgc aggcgcgtta
     3001 cgaagacctc gaagccgccg cgcacaatcc gctttgggca gaatggctgc aacaatacgg
     3061 tatgctgccg cgtcatccct cgcagcttta tcagtttgca cttgaaggca tctgcctgtt
     3121 cgccgtcgtt tggctgttct ctaaaaaaca gcggccgacc ggacaagtcg cctcgctctt
     3181 cctcggcggc tacggcatat tccgcttcat tgccgaattt gcacgccaac ccgacgacta
     3241 tctcgggctg ctgaccttgg ggctgtcgat ggggcaatgg ttgagcgtcc cgatgattgt
     3301 tttgggtatc gtcggctttg tccggttcgg catgaaaaaa cagcactgac cgcctgtgaa
     3361 aaataccgtc tgaaacatgg aaatccggtt tcagacggca tttttacgtt tggttcatgg
     3421 aaacaaacgc ttcaattctt accgcaacac gccttgtatt ttctgccgct gccgcacgga
     3481 cagggatcgt tcctgcctgt tttttcgcct tccctgcgga cggtttgcgg cttgttgatg
     3541 accgcctgcc agtagcggta gatatccgcc aatgcataag gcaactcgga ttccagttcc
     3601 gccagctcgc cttctgtgaa ttgcagacgg atagtgccgt tgtcctcttc gtcgtaaata
     3661 ccgcccaatg ccatgatggg ataaaacaac tcttcaaacg cttcatcatc gacggcttca
     3721 aaccaatcgg tcggcacaat atccaaaccg taaagataag cattgcacca tgtgtaaaaa
     3781 tcgctgccgc cgtcttcgtt ttcatacagc cacaaatcgg gcagtttttt atccgacatc
     3841 gcggcggttg tttccatcgc cattgccaaa accagccgtt cgatttcgga acgttcggcg
     3901 gcggtaaatt gcgattcgtc gcccaacact tcgggcagcc agtcgagcgg tgtcaatttg
     3961 tccggcccgc tcaacagcgc cgtcataaaa ccttgaacct cgtcgcaacg catcgtgttg
     4021 ccttgttcgc ttttggcatc caacaattcg ctcaaccgcc gtttggatgc ttcggtaaat
     4081 tttcgggaat ccatcatttt ccttttcaaa tgggttttgc gccctattat cgccgcaatg
     4141 ccgtctgaag cctttttatg cttcagacgg catcgtctgt tttcacgctc aaatcgtacc
     4201 gctgccttgc gctttcggtt tggcggcact aaattccagt ttgctcaaag cggaaaggta
     4261 ggctttggcg gtggcgacca aaacgtcggt atccgcgccc tgaccgttga cgacgcggtt
     4321 gccgcgcgcc agacggacgc tggtttcgcc ctggctttcc gtaccttgcg tgacggcgtt
     4381 gacggaataa atctgcaaag ccgcgccgct ttgcgccacg ctttcaatcg ctttgaaaat
     4441 cgcatccacg gggccggagc ctgtggcgga agcgcgtttt tcttcgcctt tgatgctgaa
     4501 cacgatgtcg gcgcgcggct cttcgccggt ttcggtgctg attttttggg agatgaattt
     4561 gtagctctcg gcattcatgc tgcccatttc gtcggatacc agtgcgtgca ggtcttcatc
     4621 gaagatttcg cgttttttgt cggcgagttc tttgaagcgg gcaaacgcgg cgttcagtgc
     4681 ctcttcgctt tccaactcga tgcccaaatc cgccagcttg gttttgaagg cgttgcggcc
     4741 ggacaatttg cccaagctca aacggtttgt tgcccagccg accgattcgg cggacataat
     4801 ctcgtaagtt tcgcggtgtt tcagcacccc atcctgatgg atgcccgatt catgcgaaaa
     4861 ggcattggca ccgacaatgg ctttgttggg ctgcacggga tagcccgtaa tggtggacac
     4921 cagtttggac gaaggcacga tttgcgtggt atcgatgccg gtttccaagc cgaacaagtc
     4981 gtggcgcact ttcaacgcca tcacgatttc ttcaaccgaa gcattgcctg cacgttcgcc
     5041 caagccgttg acagtacatt ccacctgacg cgcgccgcct tttaatgcgg caagcgaatt
     5101 ggcaaccgcc aagcccaaat cgttgtggca gtgtgccgac caaacgactt tgccgccgtt
     5161 gggcgttttg gcaatcagtt cgcggaaaaa ttcttcggtt ttgtacggga ttgaatagcc
     5221 gacggtatcg ggaatattga tggtggtcgc gcccgcttca atcaccgcgc cgcagatttc
     5281 ggcaaggaaa tcgatttccg aacgcaacgc gtcttcgcag gaaaattcca catcgtcggt
     5341 gtattcacga gcgattttca ccgctttgac cgccgcctca atcacctgct tcggcttcat
     5401 cttcaatttg tactccatat ggatggggct ggtggcgatg aaggtgtgga tgcgtttttt
     5461 cggcgcgggc gcaacggcct cacccgcctg acggatgtcc cgctcgatgg cgcgggacaa
     5521 tgaacagacc gttgatttgg taatggtttt cgcaatcgca ttgaccgcct cgaaatcgcc
     5581 cgggctggca gcggcaaaac ccgcttcgat gatgtccaca cccaattttt ccagctggcg
     5641 ggcgacgcgg attttttcct ctttggtcat agcggcgccg ggcgactgct cgccgtcgcg
     5701 cagggtggta tcaaaaataa ttacgcggtt ggtctgtgtc atttctgttc tctccagaga
     5761 ttcgtttttt tgtaaaaaag cattcaaatc cagcgacctg ccttgcgctt cagccaacgc
     5821 ggtcagcttt tgcagttgcg ccaggggcag cgacccgcgc gtgcgccatt tatagatggc
     5881 ggcggtcgtc gcggcatttt cgggatcgtg ctgtttcaac gcttcggcaa gcgcgttcac
     5941 gccgccgaaa taagcaacca agcggtctat atctaattgc atggtagtcc ttgtctaaaa
     6001 taaatcagcc tacagcagaa atatggacag gattatacgc attttggaca aaacggcaat
     6061 ataaatttga aaaatctcaa taagccgcca tagattttat taattttata cattttgtct
     6121 attttatcgc agacgcggcg tgattgttga caattgcggc agaacagggc aaattcggcg
     6181 gcacaaggcg gcaaacgaga caggacaaac caacaaggac ggaaacaatg aaatacaaaa
     6241 gaatcgtatt taaagtcggc acatcttcga ttacccattc ggacggcagt ctctcgcgcg
     6301 gcaaaatcca aaccatcacc cgccagcttg ccgcattgca tcatgcggga cacgagctgg
     6361 tcttggtgtc ttccggcgcg gttgcggcag ggttcggtgc gctgggtttc aaaaaacgtc
     6421 cggtcaaaat cgccgacaaa caggcttccg ccgccgtcgg gcaggggctg ctgatggaag
     6481 aatatacggc aaacctgtct tcagacggca tcgtgtccgc acaaatcctg ctcagccgcg
     6541 ccgactttgc cgacaaacgc cgctaccaaa atgccggcag cgcactttcc gtgctgctgc
     6601 aacgccgcgc cgtccccatc atcaatgaaa acgatacggt ttcggttgag gaattgaaaa
     6661 tcggcgacaa cgacacattg agtgcgcaag tggcggcgat gatacaggca gacctcttgg
     6721 tgctgctgac cgacatagac ggtctttaca cgggcaaccc gaacagcaat cccgatgccg
     6781 tacggctgga caaaatcgaa cacatcaacc atgaaatcat cgaaatggcg ggcggctcgg
     6841 gttcggcaaa cggcacaggc ggtatgctga ctaaaatcaa agcggcgacg attgcgaccg
     6901 agtccggcgt accggtctat atctgttcct cgctcaaacc cgatgcactt gccgaagcgg
     6961 cagataatca ggcggacggc tcgtttttcg tcccccgtgc caaaggtttg cggacgcaga
     7021 agcaatggct ggcgttctat tccgaaagcc ggggcggcgt ttatgtggac gaaggtgcgg
     7081 aacacgcttt gtccgaacag ggaaaaagcc tgctgatgtc gggcattgcc ggaatcgaag
     7141 ggcatttttc ccgtatggac accgtaaccg tgtacagcaa ggcaaccaaa cagcccctgg
     7201 gcaaagggcg cgtcctgttc ggttctgccg ccgccgaaga cctgctcaaa tcgcgtaagg
     7261 cgaaaggcgt gttcatccat cgggacgact ggatttccat cacgcccgaa atacgcctgc
     7321 ttctgaccga attttagaaa aggaaaccca tgtcaaacac acaaaaacag cttgcccttg
     7381 ccaaagcggc aaaaaaatcc gtcaacacgg cggatacgga agaaaaaaac cgcgcgctgt
     7441 ttgctatggc ggacagcttg gaagcggcgg cggcagatat tttggcggca aaccgtcaag
     7501 acttggaagc cgcggcaggc aacattcccg aaagcatgac cgaccgcctt ttgttggacg
     7561 gcaaacgcat ttgcgcgatg gcggacggca tcagggcggt tgccgcgctg cccgaccccg
     7621 tgggcgaaat actggaaacc tcgactttgc ccaacggctt ggaaatcgtc aaaaagcgcg
     7681 tggcgatggg cgttatcggc attatttacg aaagccgccc gaacgttact tccgatgcgg
     7741 cggctttggc actgaaaagc ggcagcgcgg tcgtactccg cagcggcaaa gatgcattcc
     7801 aatccgcacg cgccatcgtt gccgccctga aaacggggtt ggcacaaacc cgcatcgacc
     7861 ccgacgcgct ccagttgatt gaagacaccg ggcgcgaggg cagttacgaa atgatgaggg
     7921 cgaaagatta tctagacctg ctgattccgc gcggcggggc ggggctgata cgggcggtgg
     7981 ttgaaaatgc cgtcgtgccg gtcattgaaa cgggaacggg catcgtccac atctacgtcg
     8041 ataaggatgc ggacttagaa aaggcaatcc gcattgtccg caacgccaaa accagccgtc
     8101 cgtccgtgtg caactcgatg gaagtgctgc tggtacatga agacattgct gccgacttcc
     8161 tgcccaagct cgaacggctg ttggttcgcg accgtataga agccggactg ccgcccgtcc
     8221 gcttccgttt ggatccgcag gcggcgcggc atatcggcgg cgaagcggcg ggtgcagacg
     8281 atttcgatac cgagttttta gactacatcc tcgccgtgaa aaccgtcgct tcggtcgaag
     8341 aggcggtcgg gcacatcgaa acccacggca cgcaccattc agacggcatc gttaccgaaa
     8401 accgccacgc tgcggactat ttcacgaccc atatcgattc tgccgccgtg tatgtcaacg
     8461 cgtccacgcg ctttaccgac ggtggcgaat tcggcttggg ttgcgaaatg ggcatctcca
     8521 cgcaaaaact ccacgcccga ggcccgatgg gcttgaaaga gctaacgagt tataaataca
     8581 tcgtacaagg cacgggacag gtcagggaat aatccgaatt caaacgtctg atatagtgga
     8641 ttaactttaa accggtacgg cgttgcctcg ccttagctca aagagaacga ttctctaagg
     8701 tgctcaagca ccaagtgaat cggttccgta ctatttgtac tgtctgcggc ttcgtcgcct
     8761 tgtcctgatt tttgttaatc cactataaaa atgccgtctg aaacagtctt cagacggcat
     8821 ttccatttgc aaaaaatcaa gcattgtcca aggggacgag aatcgtacgg ttgccgttgt
     8881 gttccggtgc ggacacaatg ccttccgcct ccatctggtc aatcagacgc gcggcgcggt
     8941 tgtagccgat gcgcaaggcg cgctgtacgc ccgaaatact ggctttgcgc gttttcagga
     9001 caacggatac ggcttcatca tacatcggat cggtttcgtc gtcgccgctg cgcccgatgc
     9061 cgggcagctc ttcgctgccg ctgccgctca aaatatcgtc aacatagtcc ggctcgccaa
     9121 actgtttcaa atattcgacc acgcggtgca cctcttcatc cgaggcaaac gcgccgtgaa
     9181 cgcgctgcgg ataggcagta cccggcggca ggaacagcat atcgccctga ccgagcaggt
     9241 tttccgcgcc catttggtcg agaatcgtgc ggctgtcgat tttgctggac acttggaacg
     9301 cgatacgcgt cgggatgttc gccttaatca gacccgtgat gacatcgacg ctggggcgtt
     9361 gtgtggcaag aatcaaatgg atgcctgccg cgcgggcttt ttgtgcgagg cgcgcaatca
     9421 gttcctcgat tttcttgcct gccgtcatca tcaaatcggc aaactcatcg accacgacca
     9481 cgataaacgg cagtttttcc aaaggttcgg gatcgtcggg cgtgaggctg aacggattgc
     9541 cgattttttc tccccttgct gcggcttcgg cgattttttg attgaagccc gcaagattac
     9601 gcacacccat aaagctcatc aggcggtagc gtttttccat ttcgttaaca caccagttca
     9661 gcgcgtttgc cgccagcttc atatcggtaa cgacaggggc gagcaggtgc gggatgcctt
     9721 cgtaaatgct caattccagc attttcggat cgatcataat catacgcacg tcttccggcg
     9781 cggctttgaa aagcatagac agaatcatcg cgttgacacc caccgatttg cccgaaccgg
     9841 tcgtgccggc aaccaacaaa tgcggcgctt ttcccaagtc ggttacgacg ggctgtccgg
     9901 tgatgtcctg accgagcgcg agcgtcagct tggatttgga ttcggcaaac tcgggcgaat
     9961 tgaagatttc gctcaggcgt atcatttggc gtttcgggtt cggaagttcc aaacccatac
    10021 aggttttgcc ggggatggtt tcgacaacgc ggatggaagc cacgccgagc gaacgcgcca
    10081 agtctttttc cagattcaga acggaattgc cgcgcacgcc gacatcgggt tcgatttcat
    10141 aacgcgtaat cacggggccg gaataagaat cgacaacctt gaccttgact ttgaactccg
    10201 ccaatttttc ttcgatggtg atgctgtttt ccaacagttc ttcttcggtt tgcgtcgcct
    10261 cgggattgaa cagcggcggc agaagcaggt cggttgtcgg caggtgttcg gataccgcac
    10321 cggtctcttc cgattggaac gccccttcat ccgcttccgt atccgatacc cggcaggacg
    10381 ggcgttcaga cggcacattt tcaaacggac aaaccgcctg actgtcatgc ccgaacgctt
    10441 cggtttccga cagatattgc ccgcttgacc gctctgccgc accttcactg ccgtcatctg
    10501 caatagcggc ggtttcctcc tgccaacctc cattcaaaac atcatcggca agatggtcgg
    10561 tttcggcaat gcggctgcgt tgcgcctgct cgaattctgc cggcggttca taggtacggt
    10621 tgtagatttc cgatacggga ggcggcggcg gaatatcgat tgcgggcatg ggaactttcg
    10681 gcacttcggg tggttcgacc acccaagcat cgggcgcagc aggttcttca atatagatat
    10741 cggcagcttc atcataaacc ggaccgccgt atcccacaga cgaaacggtt tccgtgaaaa
    10801 cattttcggt ttcagacggc atttcgacat cccgtttccc gacaaccgtc cgactttccg
    10861 gaatcaggcg cgaaatccgc gcctccgcag aaaccgttgc cttgttcggt tctttcaaat
    10921 tgacggaaac gcggcggcag gcatcgcgga cggctgtgcc gtctgaaacg gactgtcctt
    10981 gggaaacatc cggggatttt gcctccgcct gccctgcatg acggcggaac ggcgcattcc
    11041 gtgcattttc ggctttgact gcagaaaagg cagacggatg ctgcttctca aaatacggct
    11101 caaatccgta atccgcagac tcggaaaacg cttctttgtc cgcatcgaac atacgggaat
    11161 acgtgcgttg aagcacaggg tcgtccaaac cgataatctg cagcccttcc atcggggtat
    11221 cggacacgcg gactttgggg accgctgttt cgtttttctc aaatgcatcg atatagcgtt
    11281 ttttcgtttc ccttaaagcc gcgccgttta aggcacgcgt tgcttcttcc aaagtgattt
    11341 ccttaaaaac cggacggacg ggcgaaattt cgctttcaga cggcatcaac ccttcagcaa
    11401 tactccggtc gaatgggatg cggcggttgt cgattacggc agttgcaatg tcttccgtat
    11461 cggcagcctc ttcctccgca gcttctgctg cttccgtttc cgcttcttcc gtcccgtttc
    11521 cactgtctga atatccgtcg gatgcgttcg gaacatccgc acggtttgca gaagcaggcg
    11581 gaacaggcct atccggttcg gattcgtgcg ccagatagtt tcggcagaaa cggacgacac
    11641 cgacgaacag ccaatacact gccgttttga cggcatggaa aagcatcagg gcaagttcgg
    11701 gaaaatcggg cataccgtct ttgatttcag gcagctccgc ctgtttttcc cctttctttt
    11761 cctgccacgc agaaacctcg cgcatccact cgcgttcgga ttgtgcgcgg acaaaaaaca
    11821 agccggcaag cgcaagcaac aaaataacga tcataactat ccaaaacata tgccgtttcc
    11881 cgcaagacaa acgattaaac gggtttattt taacgtgttt ccatcccaaa aaaaacaacc
    11941 ggtcggcaat tctgccgaaa ccgattcggc tttcggtttg cccccaccga cagtataata
    12001 gccgtccctt cccttaatct ttgcggcatt gccatgattt tccaaacagt ctggttttca
    12061 gatgtggtac tgtcggtttc gtggattgtc cttatcctga tactggcagc ttccgctccg
    12121 tcggcattcc gctcgcttgc ccgctaccgt tctgcccttc ccctgtgtac cgtaattttc
    12181 tccgcggcat ggtgtctgaa cgcctctgcc ggcggcggac agcttgcaca gatgaactac
    12241 cacctgctcg ccgtcaatct agttgctctg atggtgggca cttccgccgc cttttggctt
    12301 gccgcgctgc tgatgctgcc ctactgcctg ctgtttgccg gttctgtcgg cgcatatccg
    12361 ccgaacgctt tggtgctgat tctgcccgcg ctggccgtca accgcctgtc gcgtatgctg
    12421 gtcaaccgcc tgccacccaa tattttcatc tttattttcg tcaacggctt tctcgcttcc
    12481 gccgccggca ttctgctgac cgggctggtg ctgaccggta ttttggatgc cgcaaacgct
    12541 tttccgtccg aaatattgtg gacgaccgcc ctgcccgtct ttattctgct ggcgtgggcg
    12601 gaagcttttc tcagcggcat ttcaactgcc atatttgttg cactgaagcc ccattggatc
    12661 aacactttcg acgacaaccg ctatctgaag tccgaccgcg gcatatggcg gtagccttca
    12721 gacggcatag acaggcaaaa ccatgctttc caacatcatc cccctttcca tcggtgcggc
    12781 actcggtgca acggcgcgtt ggctgctcaa cctcgccgtt cctgccgcca tgtctcccgc
    12841 cacgggcaac ctgtttgcca actggacggg cgcgctgctc atcggcatct ttgccgaaac
    12901 catcaatcac ccgcaatgga agctgctgct gattaccggt tttctcggca gcctgaccac
    12961 gctttccgga ttttcactgg aaaccgtaac cctgctccaa tcgaatcgtc ctgcttcagc
    13021 acttgccaat attttcctac acacggcagg ttcgctgctg ctgacttggc tcgggctgaa
    13081 gataggggcg gcagtcaaat aaccgcaaca aattgcctcc ctttgttttg acataatcta
    13141 taaattagct tcgcttgttt aaatactggc tgtgccaatt atagtggatt aacaaaaatc
    13201 aggacaaggc gacgaagccg cagacagtac agatagtacg gaaccgattc acttggtgct
    13261 tcagcacctt agagaatcgt tctcttggag ctaaggcgag gcaacgccat actggttttt
    13321 gttaatccac tataccgttc tcaaattcaa attgggcttt taggtctata acaaagaaaa
    13381 agccttggca ggataaacct accaaggctt tttattaaaa aaaacgctct attactgtgt
    13441 ctaaaaatgc aaaaaaagta accatcataa cccttttgcc aaaatcaata tcatcttccg
    13501 atgaatgaat tgacggtata taagaaagaa ttaataagct cataaaccgg taagaaaaat
    13561 cagtaacaaa gattttcatt attaaccatt cttaaaaatg atcacgttcg tttgggtaat
    13621 tattataccc ttttccctct tattactaaa gcacgaatga ctttaaagga cgcgcccaga
    13681 gacaagccga aaaggcatat ctcatccgcc aaacaaaatg cccgccaatc tactccggag
    13741 ggcagttcaa caccctgtca atccttcatc agccagtatt gcaaaccgat taatgtcttg
    13801 ccgtctttaa tttcatcgtt tgccaatgcc tgacggactt cttctttcga catcaatacg
    13861 gtttccgtaa tctcgtcttc gtcattggca agcgtactgc ccaaacgcac gccttccgcc
    13921 tcgaacagat acattttttc gttgcaaaaa ccgaccgccg tataaaaact gtaaagcagg
    13981 cgtacgctgt cggtggtata aggcgtttct tcagccagtt ctcgtaaagc gcatgctgcc
    14041 atatcctcgc ccgccacatc cagcttgccc gcaggaagtt ccaatgtcgc ctgatttgcc
    14101 gcataccgcc actgccgtac caaaacgacc ttttcctcat ccgttaccgc caacacgcac
    14161 gccgcgcccg gatgccggat gacgatacgc tgcccttcat tgccgttggg caacctgacc
    14221 ttatccctgc tgatgctgac gaaaccgccc tcgtaaatgg tttcgccgcc taattttact
    14281 tccctcaaat ccacttcata tctcctttcc gtttcctatt ctgccgttca atcttcacgc
    14341 ttgccgcgct cgatttccac gccaacctcg cgcacgcctt ccaaaatacc cggcttgacg
    14401 attttcacgc gcacccacac cgcgccgaaa tatcccaaaa ccaaatcggc aatatattcc
    14461 gccaacgctt ccaaaagcag gaaatcctgt tctttcagat gtcggcgcag cgtttcgcat
    14521 acctcggcat aatgcaccgt attggcaata tcgtcgtccg aacccgcttt ctcgggaacg
    14581 ccgatgtcca aatcgacaat cagggtctgc aaccgttcgc gctcccagcc gtacacgccg
    14641 ataagcgtat ccgccttgat gccgtgcaaa aagattttat ccataatccg ccccgttttt
    14701 tgctaaaata accgcaccat tctaagtaaa gtaccgcaaa tgttcaacat accggctgtt
    14761 gctgtttcct atctgatcgg ctcactttct ttcgccgtca tcgtgtccaa gtattacggc
    14821 atggacgacc cgcgcaccta cggatcgggc aatccggggg caaccaatgt tttacgcagc
    14881 ggcaaaaaaa aggcggccgt gctgacgctc ttgggcgatg ccgccaaagg tttggttgcc
    14941 gttttgcttg cacgcgtgct tcaagaaccg ctcggtttat ccgacagcgc aatcgctgcc
    15001 gtcgcactcg ccgcgctggt cggacatatg tggccggtgt ttttcggatt taaaggcggc
    15061 aaaggcgtgg caacggcatt gggcgtgctt ctggcactct ctcccgcaac tgccttggtc
    15121 tgcgcgttga tttggcttgt gatggcattc ggcttcaagg tgtcctccct tgccgcatta
    15181 accgccacaa tcgccgcccc ccttgccgca ctgtttttta tgccgcatac ttcttggatt
    15241 ttcgcaaccc tcgcaatcgc catattggtg ttgctccgcc ataagagcaa catcctcaac
    15301 ctgattaaag gcaaagaaag caaaatcggc ggcagccgct gatttcccat ccatccctgt
    15361 ttatgccgtc tgaaccccgc ttcagacggc atccgaatat cccgccgttt taccgactat
    15421 gctcagttac agacacgcat tccacgccgg caaccacgcc gatatgctca aacacttcac
    15481 cttgttttta gtgctgcaat atttcaaccg caaagacaag ccctactggt acatcgacac
    15541 gcacggcggc gcgggtgtgt acaatctcga aggcagcgag gcacaaaaag tcggcgaata
    15601 ccggcaaggc atcgccctac ttcgacaagc aaaaaacctg ccaaccgagt taaacggctt
    15661 tatcgcgcac atacaaaaaa tcctgccctc gcccgaactt tactgcggtt ctccgtggct
    15721 ggcgcaatcg ctgacccgcg tcggcgacaa attacgcctg tttgagctgc accccaccga
    15781 ctttgtccat ctgcaaaaca atatgggcga agcaggattg ggcaaacgcg gacaagtgtt
    15841 gcgcgaagac ggttacaaag ggctgatttc cctgctgccg cccccgccgc gccgcgccac
    15901 cgtcctcatc gacccgccct atgaggaaaa acaggactac cggcgtgtaa cggaaacgct
    15961 gaaagccgct ttaaaacggt ttgagtccgg ctgttatctc atttgatatc cctgcctcag
    16021 ccgcgaagaa agccgcaagc tgcccgaaga attgaaaaaa ctcctgcccg acaactacct
    16081 tcacgccgaa cttcacgtcc acgcgccgaa agccgacggt ttcggtatgc acggcagcgg
    16141 aatgttcgtc atcaatccgc cctatctgtt ggcggaacaa ttggcggcaa acctccccgc
    16201 cctgacgcgg ctgctggcgc aagacgaagg cgcgcgctac cttttggaca gcaaaatccg
    16261 ctgaccccga tgccgtctga aacccttcag acggcatctc ccatcaaaca aaaccggacg
    16321 atataccggc agccggcact tttatagtgg attaacaaaa atcaggacaa ggcgacgaag
    16381 ccgcagacag tacaaatagt acggaaccga ttcacttggt gcttcagcac cttagagaat
    16441 cgttctcttt gagctaaggc gaggcaacgc tgtactggtt taaatttatc cactataaga
    16501 ataaatatcc cctcatccgc ctgccgcgtt ccgacttgcc ccgcgccgtt tttttccact
    16561 acaatcccac gcgatatctg gcggaacgca ccaaaggaac gccccgcagc aatctgccgc
    16621 ctttcagacg gcacaaacat ttccgaaacg agcaaactat ggacacactg acccgattcc
    16681 tccccgaaca cctgcaacaa aaccagctgc ccgaagcact ctgcggcgtt ttactgtccg
    16741 ttgtttccgc ctgcaccgaa atcaacgcca aagtccgcct cggcgcactg gccggcgtat
    16801 tgggtatggc gggcacgggc aatattcagg gcgaagacca aaaaaaactg gatgttatcg
    16861 ccaacaacat catgattgac acactcaaag ccaaccctgc cgttgccggt ttggcaagcg
    16921 aggaagaaga ctctttcgta agtgccggtg aaaacggacg ctatctcgtc ctattcgatc
    16981 ctttagacgg atcgtccaat attgatgtca acatttccgt cggtacgatt ttctccatcc
    17041 ttgaaaaacc cgaaggcgca ttggcaaccg aatcattcct tcaaacgggc agacagcagc
    17101 ttgccgctgg ttacgttctt tacgggcctc aaacccagct cgtattcaca ttcggacacg
    17161 gcgtatatat gttcacgctc aatgccgaaa acgaatttgt gctgacaaaa gaaaaaccga
    17221 aagtacccga aagtaccaaa gaatttgcca tcaatatgtc caaccgccgc cactggctgc
    17281 cccccgtcca acaatacatc gacgagctct tggcgggcga aaccggcacg cgcggcaaaa
    17341 actacaatat gcgctgggta gccagcatgg ttgccgaaat ccaccgcatc ctgatgcgcg
    17401 gcggcgtgtt catgtatccg caagacaaac gcgaccccgc caagcccggc aaactgcgcc
    17461 tgatgtacga agccaaccct atgagcctga tactcgaaca ggcgggcgca tcggcaagca
    17521 acgcatatca agccatgctc gacatacagc ccgaaaacct gcaccaacgc gtcgccgtca
    17581 ttatgggcag cagcgaagaa gtggattacc tcaaccgcct gcattcaaaa taaaaggcag
    17641 cctgaccgat aaagaaaggc ggcagcgcgc atccgacgct gccgccgata tttcgtttat
    17701 agccttaaaa agatagaaaa ccacctttcc gaacggcaaa aatgccgtct gaaaagtttt
    17761 cagacggcat tttaaaaatt aaagcccgaa tttatttgcc cgctgctttt tgcaggatgg
    17821 cgtacaactc gtctttcagt ttcaatttgg cttttttcag ctcatcgatg gtttccgcac
    17881 cgctggtaac cggattgttg accagaccgg taattttatc gtccagctcg ttgtgttcgt
    17941 cgaacagacg ggcgaagcgg gaattttcct gtttcaattt ggaaatcaaa tcacggtatt
    18001 ctgggaacat atcgctttcc tctcttggtt tacggttaaa aagtcaaatt gaatctttac
    18061 attaattata acaaagataa tatttttatc cagtgtttta tcggatacgg caaaattttc
    18121 ttttaacacc gccgtccggt tgataaaaac gttgacaata tcacgcttta cgcataaatt
    18181 ttcagccttt cctactgtat agtggattaa caaaaatcag ggcaaggcga cgaagccgca
    18241 gacagtacaa atagtacgga accgattcac ttggtgcttc agcaccttag agaatcgttc
    18301 tctttgagct aaggcgagac aacgccgtac tggtttttgt taatccacta tatatgaaag
    18361 gtacgcccca gtttccccaa tgtggatttt cagcgcgtgc agtagaggtg ctgacccaat
    18421 tggcagaccc tttgcttttg ttaatatcct agaaaaccca gaaattcgca gtactctacc
    18481 actcatcgcc aatcggccaa cctttccaca gctttgggtt aatggtgagt taatcggtgg
    18541 tagtgatatt atcctacaaa tgtaccaatc aggtgagcta aaaccactca ttgaagagca
    18601 tagcccaaag gtctgattac ttaatatctt aaaataaata tcaaaaaaga ctgctgatga
    18661 cattagcggt ctttttttga tggtcaagat tgatagtttg gattgaatta tttagccata
    18721 ttaaatacaa taatcagcat gccttgtatg aatcatcaat caaactcagg cgaaggagtg
    18781 cttgtggcta aaacatattt attgactgca ttgataatgt ctatgacaat ctctggatgt
    18841 caagtcatcc atgccaatca aggtaaggtt aatactcatt ctgctgtcat cacaggtgca
    18901 gacgctcaca cgcctgaaca tgcaacggga ctgatcgaac aaaagcaggt gattgcaagt
    18961 gattttatgg tagcgtcagc caatccatta gcaacacaag ctggctatga tatcttaaag
    19021 caaggcggta gcgctgcaga tgcgatggtg gcggtgcaga cgacactaag cttggtagag
    19081 ccacagtcgt caggcttggg cggtggtgca tttgtgttgt attgggataa taccgccaaa
    19141 acattgacca catttgatgg gcgtgagacg gcaccgatgc gtgcgacgcc ggaattattt
    19201 ttggataaag atggtcaacc attgaaattt atggaagcgg tggtcggtgg tcgctcggtg
    19261 ggtacgcctg ctatccctaa actgatggag acaatacatc agcgatacgg tgtattgcct
    19321 tggggaaaat tatttgatac accgatccgc ttggcaaaac aaggctttga ggtgtcgcca
    19381 aggcttgcca tctcggttga gcaaaatcag cagcatttgg cacgctatcc aaaaacagcc
    19441 gcttattttt tgccgaatgg tgtgccgcta caagcaggca gcttgctgaa aaatttagaa
    19501 tttgctgaca gtgttcaggc gttagcagct caaggtgcaa aagctctgca tactggtaaa
    19561 tatgcccaaa atatcgtttc agttgtccaa aatgctaagg ataaccccgg tcaattatcc
    19621 ttacaagatt tatctgatta tcaagtggtg gaacgcccgc ctgtttgtgt gacttatcgt
    19681 atttatgaag tatgcggtat gggtgcacca agctcaggtg ggattgctgt gggtcaaatt
    19741 ttggggattt taaatgaatt ttcacccaat caggtggggt atgatgctga aggtttacgt
    19801 ctcttgggcg acgcttctag gcttgcgttt gcggatcgtg atgtatattt gggcgaccct
    19861 gattttgtac cagtacccat tcgccagttg atttctaaag actacctaaa acatcgcagc
    19921 cagctgcttg agcagtcgga taaggcattg cctagcgtat ctgcaggcga ttttattcat
    19981 gagtgggtgt cctcacaagc gattgagtta ccttctacca gtcatatatc aattgtggat
    20041 aaggcgggca atgtgctatc aatgacgact tccattgaaa atgcgtttgg ctcaactttg
    20101 atggcaaatg gctacctgct gaataatgag ctgacagact ttagttttga gccaataaag
    20161 cagggcaaac aggtcgccaa tcgtgtcgag cccggcaaga gaccacgctc ctcaatggca
    20221 ccaaccatcg tatttaaagc aggcaagcct tatatggcaa tcggctcccc aggtggtagc
    20281 cgtatcattg gctatgtcgc taagacgatt gtggcacata gtgactggaa tatggatatc
    20341 caagatgcca tcagtgcacc caatttatta aatcgctttg gtaactatga actagaaacg
    20401 ggtacaaccg ccctccagtg gcaacaagca ttaaatgatt tgggctataa gactgacgtg
    20461 cgtgagctaa attcaggtgt tcaagccatt attatcgagc caagcaggct ggttggtggt
    20521 gccgatccac gccgagaagg tcgagtgatg ggtgattaga ggtgaagctt gtattttgtg
    20581 aatttgaccg cattaagtta atattaaaat agggggaaat tgtgagtaat caaacaaaaa
    20641 tacaagccat caagcaagct tctgagcaga tcttcgcaat ttgtgagacg ccaaacacag
    20701 cattacaagc cattcatctg attttaagac atggtggggc aggagagttg tcttggcaag
    20761 tggtgtatca gcgggttatg gctgataaag atgtggttgg tgctggttat ttgattgatt
    20821 ttgcacaaac tgccgaaaat ttaccatttg atgtattgcc tttgggtagc cttgtactaa
    20881 cataaaggta atgagacgct aaaaaccagc atgttaaata aattacctga taatgccaaa
    20941 gaaaatttac gcattatgga ctatctgcct taggttttga agtatttttt tatacaaaaa
    21001 acactcatga taccctgatt acacaaagga gccgagaaca tgttttcaaa aagcgttacc
    21061 ctcgcacaat atgaccccga tttggcagca gccattgccc aagaagacca acgccagcaa
    21121 gaccacgtcg agctgattgc ctctgaaaac tacgtcagct gcgccgtaat ggaagcgcaa
    21181 ggttcccagc tgaccaacaa atacgccgaa ggctaccccg gcaaacgcta ctacggcggc
    21241 tgcgaatacg tcgatattgt cgaacaattg gcaatcgacc gcgtcaaaaa actgttcggc
    21301 gcgcaatacg ccaacgttca accgcactcc ggctcgcaag ccaaccaagc cgtgtacgct
    21361 tccgttttaa aaccgggcga caccattttg ggtatgtctt tggcgcacgg cggccacctg
    21421 acccacggcg cgagcgttaa tatttccggc aaactctaca atgccgttac ttatggtttg
    21481 gatgaaaacg aagtgctcga ttatgccgaa gtggaacgct tggctctcga acacaaacct
    21541 aaaatgattg tggccggtgc gtctgcctac gcgttgcaaa tcgactgggc aaaattccgc
    21601 gagatcgccg ataaagtcgg cgcatacctc tttgtcgaca tggcgcacta tgccggactg
    21661 attgccggtg gcgaatatcc caaccccgtg ccattctgcg acttcgtgac caccaccacc
    21721 cacaaaaccc tacgcggccc tcgcggcggc gtgattttgt gccgcgacaa tacccacgaa
    21781 aaagcgttaa actccgccat cttcccaagc ctacaaggcg gtccactgat gcacgtcatc
    21841 gccgccaaag ccgtagcgtt taaagaagcg ttgcaacccg agttcaaaca atacgcaaaa
    21901 caagtgaaaa tcaatgctgc cgccatggca gaagagttgg ttaaacgcgg tttgcgcatc
    21961 gtttccggcc gcaccgaaag ccacgttttc ctcgtcgacc tgcaaccgat gaaaatcacc
    22021 ggtaaagccg ccgaagccgc tttgggcaaa gcgcacatca ccgtcaacaa aaacgccatc
    22081 ccgaacgatc cggaaaaacc cttcgttacc tccggcatcc gcatcggctc cgctgccatg
    22141 accacacgcg gttttaacga agccgacgcg cgcgtattgg cgaacttggt tgccgacgta
    22201 ttgtctaacc ccgaagacga agcgaatctg gaaaacgtcc gcaaacagat taccgccctc
    22261 tgcgacaaat acaccgttta cggcgcgtaa gcctttttaa aaatattccg ccaagcaatc
    22321 caatgccgcc tgaaatctca caatgtttca ggcggagacc tttgcaaaat tccccaaaat
    22381 cccctaaatt cccaccaaga catttagggg atttctcatg agcaccttct tccagcaaac
    22441 cgcccaagcc atgattgcta aacacatcga ccgtttcccg ctattgaagt tggaccaggt
    22501 aattgattgg cagccgatcg aacaatacct gaaccgtcaa agaacccgtt acctcagaga
    22561 ccaccgcggc catcc
//
LOCUS       DAXISH010000030        22536 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.030, whole genome shotgun sequence.
ACCESSION   DAXISH010000030 DAXISH010000000
VERSION     DAXISH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 22536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22536
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.030"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(408..2381)
                     /locus_tag="ACFOV4_001149"
     CDS             complement(408..2381)
                     /locus_tag="ACFOV4_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyocin knob domain-containing protein"
                     /protein_id="HFC7619170.1"
                     /translation="MHPIETPDKTFHDGDGVSELGTILPAWWLNQVQSELLAVLTAAG
                     IQPDKSQPNQLLAALNRLAVVTTGDQTITGQKTFTAQTQFQSGIHLSANQTNWNGGHK
                     AYIGADADNAHIVFGDDTLRLHGANNRISYNNHDIFHKANKPRFAEDIEGKPNTLSGY
                     GIGNFKVETFRGDLNTLKTDGIYSLPTAGGSSNLPVENTACHIQVIAGTKHGWCRQLG
                     YPAYTSDVYERHQTSSANDNWSAWKKLNSDGIPVGAIVSFPKAVRNPAGYLKANGTTF
                     AQNTFPDLYRALGNSNRLPDLSRTDIGITAWFPSDQIPTGWLAFDDIRTRVTETAYPE
                     LYRLLTGKYGSIQNVPQAEDRFIRNAANGLAVGTKQEDEIKRHVHKVFSHWVNHPHAA
                     ALGYEDHNERQRSALVSTWTDENLNDNGFLTPRPDSKMATGGDENRPKALVLKLCIKA
                     ADTLGEAVFWIKSHGETVNAGALDAGTLAQNLQDKADRAHTHTAAQIQGLDEKISTAV
                     AAQFTRQTIGGVDIVRFPDGTMIQTGSYRFTRSGGPIENEVVFPVAFADGNVKCFVSE
                     RHSGRVTGDRRQHNWLFIRAKNHAAAIITNWYEGSCDWMAIGKAASGNAASSPIGPEI
                     PETNEEPQRESGRTSTGPRNRRHRDSLLEALQD"
     gene            complement(2392..2952)
                     /locus_tag="ACFOV4_001150"
     CDS             complement(2392..2952)
                     /locus_tag="ACFOV4_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HFC7619171.1"
                     /translation="MSYQDILRGLLPPVSYARNAPRVRAQAEIDGAALDAVAESAQSV
                     ADAVDPRSAGQMLADWERVLGLDGTGKNRQRRVLAVMAKLNETGGLSIPYFVRLAEAA
                     GYQIQIDEPQPFRAGVNRAGDRLAPQEIMWVWHVNVRGGNNRITRFRAGISAAGDRLT
                     DYSDAVIESLFNRLKPAHTAIRFTYR"
     gene            complement(2949..4003)
                     /locus_tag="ACFOV4_001151"
                     /pseudo
     CDS             complement(2949..4003)
                     /locus_tag="ACFOV4_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004284601.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
     gene            complement(4017..4364)
                     /locus_tag="ACFOV4_001152"
     CDS             complement(4017..4364)
                     /locus_tag="ACFOV4_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage GP46 family protein"
                     /protein_id="HFC7619172.1"
                     /translation="MDKELNPDTGDYTGRTVDTLQNAVYIRLMTPLGSWWADKTLGSL
                     LHLLQREKDLQRVSLLAEQYADEALQPIVKSGRADKITVRAEQPHDGRLILHIRVDTA
                     AGGFDYRHEVPVI"
     gene            complement(4464..5132)
                     /locus_tag="ACFOV4_001153"
     CDS             complement(4464..5132)
                     /locus_tag="ACFOV4_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HFC7619173.1"
                     /translation="MSLSKLAKKTAQTAKNIGETLRAAFRGKITLVVSSEPIQRVQLS
                     GLADETLQDLEHLQEYGFASHPPDGSEAVVIPLGGNTSHGVIVCSQHGSYRIKNLKPG
                     ETAIFNHEGAKIVIKQGKIIEADCDVYRVNCKQYEVNAATDAKFNAPLVETSAVLTAQ
                     GQINGNGGMAVEGGDGATFSGDVNQTGGSFNTDGDVVAGNISLRQHPHTDSIGGKTLP
                     AEPA"
     gene            complement(5129..6274)
                     /locus_tag="ACFOV4_001154"
     CDS             complement(5129..6274)
                     /locus_tag="ACFOV4_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004284604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein"
                     /protein_id="HFC7619174.1"
                     /translation="MQNNSYGYAVSVRVGGKEHRHWERYDIDSDFLIPADSFDFVIGR
                     LGPEAAIPDLSGESCEVVIDGQIVMTGIIGSQRHGKSKGSRELSLSGRDLAGFLVDCS
                     APQLNVKGMTVLDAAKKLAAPWPQIKAVVLKAENNPALDKIDIEPGETVWQALTHIAN
                     SVGLHPWLEPDGTLVVGGADYSSPPVATLCWSRTDSRCNIERMDIEWDTDNRFSEVTF
                     LAQSHGRSGDSAKHDLKWVYKDPTMTLHRPKTVVVSDADNLAALQKQAKKQLADWRLE
                     GFTLTITVGGHKTRDGVLWQPGQRVHVIDDEHGIDAVFFLMGRRFMLSRMDGTQTELR
                     LKEDGIWTPDAYPKKAEAARKRKGKRKGVSHKGKKGGKKQAETAVFE"
     gene            complement(6264..7595)
                     /locus_tag="ACFOV4_001155"
     CDS             complement(6264..7595)
                     /locus_tag="ACFOV4_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA circularization N-terminal domain-containing
                     protein"
                     /protein_id="HFC7619175.1"
                     /translation="MSGWHTLLQDASYKGVGFDIEVVDESNGKALAEHARPFVQGIDL
                     EDMGMTGRQVQINAVFWGKGYAGRLKKLLDALEQPGGGVLVHPVWGRMHNMIAASWSY
                     RHEADYVDYAGIDITFREAAEAQEIFVFENAFLVELEALIADIDTYREAAIGFVDAVL
                     AVDAGVSALWGSALGIWSAASGTFGAVRRLFDLDKIAFPDRGGYSAAAFKNGSAKLFA
                     DISVMVDTGIRREAGLADNAMHHAGWSPRQRFDGAVAVADRAAAIPDNLLTGRFSDGL
                     QNRLNRLTAKQVQPVAQAVRLLSTSSLLSVATALIEAHGEEMTAPDLIEVNRAMRRRM
                     QAEIAALRAVQTAAAESGGLTANAVYTEAYQTAESLRAAAGRLNALVAAAINQKPPLI
                     VRQAPIDGTIHQIAHEFYGDMARAAELVRLNPHIHHPAFIKRGTLVNSYAK"
     gene            complement(7595..9766)
                     /locus_tag="ACFOV4_001156"
     CDS             complement(7595..9766)
                     /locus_tag="ACFOV4_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRTRC system protein F"
                     /protein_id="HFC7619176.1"
                     /translation="MANGNMKLSLVLTARDDGARRLLADTQRQLDRTAKSRAQLERQS
                     HTYALTGIRSEKQIQREIMLTQAAFNRLARSGKASQNDLARAAVATRNRIRELNAELK
                     QGTGFADKMGKIGRFGAAAVAGGAAAYTVLKPAMDNRKQLDENINRVSRQAFIEDNSK
                     SAAWIATEGAQQIKDLALELVEKNGGTHDKALDLISGMMTTSLNFAQTKNEAQAAYAF
                     ALASEGSGEDTAKLIKTLKDGGMSGKDLQLGLEHVLQSGLDGTFEVRDMVRELPSLLP
                     AAQQAGMNGVGGLDYLLSLLQSAANKSGSPAEAATNVQNLLSKTLSPYTIGRLKKMAN
                     PNDPKKGVDWIGSVVQGKQNGENAVQVLSRLADAMLVKDKQYQDYKKRAAAGDKTAAE
                     QANMLKGALLAQLLPDLQAKQGLLAATDMTQIREYMASLAGVTLDNGKIAKNNEARML
                     SAAAQQEQQESLAMLRESLTGTLVDMETSFKKLAAEYPNATLALQALTTAATAASAAM
                     LLTAGGGKGAGFLKDVGSKALVWGKASAGGVAAGATAAGGKLLSWGKSAGSGLMNNPA
                     LVKRAGLLGMLLYSESLGDGTLPKGLRGTKTTPEMINRLKNNGIRFEPAPKREQARGG
                     VPQYLAAPSAQPTDKMLSPLFSTQTAAYQAAIQQQTAAYQAALAQDTAAVTTGLAQVQ
                     SAMASASQTINTNVSLNIDGRVIANEVSRYQVAMFGRGAGQ"
     gene            9921..10445
                     /locus_tag="ACFOV4_001157"
     CDS             9921..10445
                     /locus_tag="ACFOV4_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619177.1"
                     /translation="MNMKKLISAICVSIVLSACNQQSKTAQAEEPVQSIQAADCTAPM
                     DITVEQYLINLEQAFKTQNVSTKIHNKNIVKTDCGYDLTLVMDFGAIALKLDEQQKIR
                     AISVGYILKTDGEKGQNLVNNAINGLHSIQAVLSLTTTDKLGESEAGKQLRQRIQSDR
                     SNSAKRRSGRWYFI"
     gene            complement(10547..10816)
                     /locus_tag="ACFOV4_001158"
     CDS             complement(10547..10816)
                     /locus_tag="ACFOV4_001158"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619178.1"
                     /translation="MPKTVRRYGEPRRAVGGGAVKRSYLTAHKSYRQAVILMAKAGIG
                     ADAVRDMCHAELSAWFEDILSSLGIKTPKEEGVIVSKRLRKPEGK"
     gene            complement(10756..11121)
                     /locus_tag="ACFOV4_001159"
     CDS             complement(10756..11121)
                     /locus_tag="ACFOV4_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619179.1"
                     /translation="MITVKLTHGLTYNGKVVSELRLKPLTVGGELAAFALIDDLPELP
                     ENATKAELLQRDVLETLTYWSQQIEAQGIPSDILTAQWLMENLSTEDYHTVMAAQEDL
                     CLKPSAATASPDAPSAAEQ"
     gene            complement(11125..11502)
                     /locus_tag="ACFOV4_001160"
     CDS             complement(11125..11502)
                     /locus_tag="ACFOV4_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFC7619180.1"
                     /translation="MSDATYTGAVIMEVNGRDIEIVSIKPQTTTGRKPVKTMNRNGRV
                     NGYCDGVTEHKLSVTAAIPIDGTEIDWDNITKAKITIYPINDEGRRTSYLDCFTVDTS
                     EQYEVDNEARIDIEMIALHKIKE"
     gene            complement(11567..12976)
                     /locus_tag="ACFOV4_001161"
     CDS             complement(11567..12976)
                     /locus_tag="ACFOV4_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFC7619181.1"
                     /translation="MPHIDFDTIPGSIRVPGQYIEFNTRNAVQGLPQNPQKVLMVAPM
                     LTAGIQPALEPVQLFSDAEAADLFGQGSLAHLMVRQAFANNPYLDLTVIGIADHSAGV
                     QATATVTLSGTATAPGVVEITIGGKQVSTAVNTGETAATVAGRLKTAITAADVTVTAS
                     GSGVAVTLTAKHKGEIGNESGLTVSTGNTGLTYQANVFTGGAKNADIATALSKVAGKH
                     YHIICSPFSDDANAKALSNHITNVFNAIEQRGCIGVLGMSAALSTATTATGKINDGRI
                     TCAWYKGAVEPNGIIAAGYAAVLAFEEDPAKPLNTLEIKGLAVTPDAQWPWFAECNNA
                     LYNGLTPLTAVNNRVQIMRAVSTYTKSANNTDDPALLDITTIRTLDYVRRSVKERIAL
                     RFPRDKLSDRLLPKVKSEILDVLIKLDQAEIIENAEANKGKLVVARAQNDPNRVNAII
                     PADVVNGLHVFAGRIDLIL"
     gene            complement(12979..13176)
                     /locus_tag="ACFOV4_001162"
     CDS             complement(12979..13176)
                     /locus_tag="ACFOV4_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2635 domain-containing protein"
                     /protein_id="HFC7619182.1"
                     /translation="MSKIKVTAADGLRVPTEHNPHEYIGQEPVEVDGNSLYYRRMIDD
                     GDLVVVEDAAPNTKTRNTKGE"
     gene            complement(13173..13823)
                     /locus_tag="ACFOV4_001163"
     CDS             complement(13173..13823)
                     /locus_tag="ACFOV4_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004285295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage protein Gp37"
                     /protein_id="HFC7619183.1"
                     /translation="MITDIEQAITDRLKRGLGRMVRTVKSYNGEADDLAGQIHTLPAV
                     WVTYGGSKVEPASTGGVCGRYQDTAEFVVMVAARNLRNEQAQRQGGIDSREIGSNDLI
                     RAVRRLLDGQRLGFADSRGLVPKAVRAIANHVLVQNAAVSIYAVEYAIRFNTCGLEND
                     RYPERTDNPDDPNHIFTKYQGTLSEPWPDFEGLDGKIYDPQSADEIPVNLTLKDKQ"
     gene            complement(13813..14235)
                     /locus_tag="ACFOV4_001164"
     CDS             complement(13813..14235)
                     /locus_tag="ACFOV4_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage protein Gp36 family protein"
                     /protein_id="HFC7619184.1"
                     /translation="MAYATVEDMVARFGELEVLQLTDRNNEGLIDREVAQTALVDATA
                     EIDAYLGRFRRPFEDLPPILVRLCCDIARYRLTAAQGVLITDEIRNRYKIDVLDLLRA
                     MAKGEVQLGVDDSGEEVAAGEDGIVFVNGKNKVFGRDH"
     gene            complement(14235..14633)
                     /locus_tag="ACFOV4_001165"
     CDS             complement(14235..14633)
                     /locus_tag="ACFOV4_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619185.1"
                     /translation="MAKTNNKPETAETAAPSFEDIKAELDAVQAELAAARNDVEMLTT
                     ALEKAEDDKKALSAELAELKVQHTQRAADALADSRDVMLVSTGADGKEFWRGGLLFDG
                     GWREVKRAEVGEAVWKAICAEPMLQRKAVE"
     gene            complement(14698..15606)
                     /locus_tag="ACFOV4_001166"
     CDS             complement(14698..15606)
                     /locus_tag="ACFOV4_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu-like prophage major head subunit gpT family
                     protein"
                     /protein_id="HFC7619186.1"
                     /translation="MDKSAILTAITAAFRKEFQTGLESVKPDYTAVAMTIPSNTATNT
                     YAWLGKFPQMREWVGSRQIEKMNKQAMSLDNKKFEATVGVARTDIEDDQVGMYRPMMA
                     AMGESAAALPDTLVWGLLKKGKTTVGYDGQYFFDTDHPVYEKSDGTGQNTPHSNLTTG
                     TDNDAPTFYVVDDTKTLKPLIFQNRTDSEFETKFDPSKSDRVFMEDEYLYGSRRRCNA
                     GFGLWQLMHMAEKTALTRENLAAIIVKMQKIKADGGYVLNVKPSLLVVPPELEDKARE
                     LLEADKINGTTNTFKGRLKLHVCVHL"
     gene            complement(15606..16667)
                     /locus_tag="ACFOV4_001167"
     CDS             complement(15606..16667)
                     /locus_tag="ACFOV4_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage protease"
                     /protein_id="HFC7619187.1"
                     /translation="MSKNAQKTLLAVCSFEVQPKDGRIQLLPYGEFRAVDGRPTDVPA
                     WYLTEENGHDVALLANSSRNQLVVDYEHQTLYKEKNGQPAPAAGWMRWLEFTPKGMFA
                     EVEWTDKAAAAIAAKEYRYISAVFSYDTKGYVSKIFHAALTNFPALDGMDEVLAAASA
                     QILKSETEQNPMKELLQQLFGLPDAGEEELKAALSALVEAKPKDVALSADVFAQLAEK
                     DSRITALTAQTAKPDLTKYAPISVVQELQSKVAALTAKQEADKGNELITAALTSGKLL
                     PAQKEWAEGVLKQPGGLAFLTGFIENAQPVAALAGSQTGGKAPDERVAALTAEEAAAA
                     KMLGMSGEEFVKIKESEGK"
     gene            complement(16898..17314)
                     /locus_tag="ACFOV4_001168"
     CDS             complement(16898..17314)
                     /locus_tag="ACFOV4_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HFC7619188.1"
                     /translation="MIDVKIDNIFVVLNQIERLGNGIENRYLLMRRLSETMHTAVKLN
                     FRYAGRPKWLGLKYRDGKPLSDSGRLKDSFSTLSDNDTALVGTNIVYAAIHNFGGMAG
                     RNRKVRIPQREFLTLTDDDKQALMDDVQDYFSGLIP"
     gene            complement(17442..18767)
                     /locus_tag="ACFOV4_001169"
     CDS             complement(17442..18767)
                     /locus_tag="ACFOV4_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HFC7619189.1"
                     /translation="MPAPDLGFALSLPPKKAIEWLESKKVTAESYRNLTASEIAKVYT
                     IARMTDLDMLNDIKTSMVESAKSGQSFDDWRKGILNLLGNKGWLHPNGHNGKDIIDPA
                     TGEVFGSPRRLETIYRTNMQTAYNAGQYQGYMANIDARPYWMYDAVGDSRTRPAHSAI
                     DGLVYRYDDPFWATFYPPNGYNCRCSVIALSERDVERQGRIVGQSTADNLVETHKIYN
                     KKGDTYLTLAYKAPDGSLYTTDRGFDYNAGRMNYRPDLDKYDRALAHQFAKAEMGGAD
                     FKTSFKQLEKEFYEVKQRLDIDGKPDKEQKIKIRNALSRQLKFAAGVLSKETQELAGM
                     TRATVWLSDDTLVKQVDSREGQSFGTDLYAMLPDLIHEPEYIFYDKSRGKESFVLLGK
                     PLEGNEKYRLMAVLKYLPQYDSIFLDSFRRADEKEIVKSKKRYEMKKGY"
     gene            complement(18754..20322)
                     /locus_tag="ACFOV4_001170"
     CDS             complement(18754..20322)
                     /locus_tag="ACFOV4_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF935 domain-containing protein"
                     /protein_id="HFC7619190.1"
                     /translation="MAKKNNKTKIQKPEAALQTDVAQITATGRVIAEHPSNFITPQKM
                     RALFEDAESGDIRAQHELFADIEERDSDIAANMGTRKRALLTLNWRVAPPRNATPEEE
                     KLSDQAYEMMDSLPTLEDLIMDLMDAVGHGFSALEVEWVFSDGLYLPRNFIHRPQSWF
                     KWDKDNGLLLRTRENPEGEALWPLGWVVHTQKSRSVQQARNGLFRTLSWLYMFKHYAV
                     HDFAEFLELYGMPIRIGKYGAGATKEEKNTLLRAVAEIGHNAAGIMPEGMEIELHNAA
                     SGTMATSNPFLQMADWCEKSAARLILGQTLTSGADGKSSTNALGNIHNEVRRDLLVSD
                     AKQVAQTITSQIIGPFLQINYPNADPNRVPKFEFDTREPKDIAVFADAIPKLVDVGVQ
                     IPESWVRDKLVIPDVQEGEAVLVRQVPDNPINRTALAALSAHTVPSKATGRHQEILDG
                     ALDDALVEPDFNSQLNPMVRQAVAALNACNSYEEADAALNALYPNLDNAKLRTYMQQA
                     LFISDILGQDHARA"
     gene            complement(20322..21944)
                     /gene="terL"
                     /locus_tag="ACFOV4_001171"
     CDS             complement(20322..21944)
                     /gene="terL"
                     /locus_tag="ACFOV4_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HFC7619191.1"
                     /translation="MKTKEFLKSLAELAASLRQVIEAEVDGFDALPKAIAARRAKVFD
                     PVGGYEYFVNTYFPHYIRSPEKSELHAFLFSRLPEIIRSPKGENEAVGAPRGEGKSTQ
                     VTQLFTLWCIVTGQKHYAVIVMDSIDQAYPMLEAIKAELEFNPRLKTDFPEVCGQGRV
                     WQAGTIATANDVKVQVAGSGKKLRGLRHGPYRPDLTILDDIENDEQVRNPEQRDKLNA
                     WLTKTVLPLGGVGQKYDVIYIGTILHYDSVLNRTLNNPFWRGVKFKAMKRWPDRMDLW
                     DRWEELFRNDGETVAEAFYLANKDEMERGAQTSWAARGVLALMKIRARDGHATFDSEY
                     QNDPVSGEDAPFAKSMKFWNDLPSDLVYFGALDPSLGKAGASRDPSAIIIGGYQRETG
                     KLYVVEAQIKKRLPDLIIEDVIRLHRQYRCKLWFVETVQFQEFLKDELVKRSAARGIP
                     VPARAVKPVSDKLLRIETLQPHMANGLILLNESQQTLIQQFRHFPKADHDDGPDAVHM
                     LWSGAVANCVPIEWQSPTDNDFDDEIKSKWSR"
     gene            21956..22468
                     /locus_tag="ACFOV4_001172"
     CDS             21956..22468
                     /locus_tag="ACFOV4_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619192.1"
                     /translation="MTGFISNAFIGLKEAGSLLKGFNQLKTEAEVAQKTIELNQIIAG
                     IQTDLFEAQSSYTAAISRIDELEKELVAVKNWSTEKQRYQLYELAPGSFVYRLKTEMA
                     NSEPIHDICPQCYEQGVKSILQFNGYEGAFHKYSCSRCQTIILGERLKSDVEVFSVGG
                     SRYGRLIDGY"
     gene            complement(22465..>22536)
                     /locus_tag="ACFOV4_001173"
     CDS             complement(22465..>22536)
                     /locus_tag="ACFOV4_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFC7619193.1"
                     /translation="PKHLPAFVEVLEPFGAEVEKKFG"
BASE COUNT         4542 a         6359 c         5974 g         5661 t
ORIGIN      
        1 ccgcgtttgg ggtctggatt cccgcctgcg cgggaatgac ggcggcgggg gtttctgttt
       61 tttctgatag attcctgccg cgtttggggg ctggattccc gctttcgcgg gaatgacgaa
      121 agaggcggga atgacgaaag cggcgggaat gacgaagagt ggcaggattg gcggggcata
      181 ggtttcgggg gattggcggc gcggccggtt tcggtcggat tgcttggatc ggcgggctga
      241 agcccatctc tacagcccat ctctacagcc atctctacag ccatctctac agccatctct
      301 acagcccatc tctacagcca tctctacagc catctctaca gccatctcta caacccatct
      361 ctacaacccg tctctacagc catctctaca gccatctcta cagcccgcta gtcttgcagt
      421 gcctcgagca agctgtctcg gtggcggcgg tttcgggggc cggttgatgt tcttccactc
      481 tctctttgcg gttcttcgtt ggtttcaggt atttcggggc ctatcgggga gctggcggcg
      541 tttcccgagg cggctttgcc gatggccatc cagtcgcaac tgccttcgta ccagttggta
      601 ataatggcgg cggcgtggtt ttttgcgcgg ataaacagcc agttgtgttg ccttcgatcg
      661 ccggtaacgc gtcccgaatg gcgttcggat acgaagcatt tgacgttgcc gtcggcaaag
      721 gcgacgggga agacgacttc gttttctatg gggccgccgc ttcgtgtgaa cctgtagctg
      781 ccggtctgta tcattgtgcc gtcggggaat ctgacaatat ccacgccgcc gatggtttgg
      841 cgtgtgaatt gcgcggcaac ggcggtgctg attttttcgt ccagcccttg gatttgggcg
      901 gcggtgtggg tgtgggcgcg gtctgctttg tcttggaggt tttgcgccag cgtgcccgcg
      961 tccagcgcgc cggcgttgac ggtttcgccg tgggacttta tccagaacac ggcttcgccc
     1021 aaggtgtcgg cggctttgat gcacagtttt aaaaccaggg ctttggggcg gttttcgtcg
     1081 ccgcctgtcg ccattttgct gtccgggcgc ggggttaaaa agccgttgtc gtttaaattt
     1141 tcgtccgtcc aagtcgatac gagcgcgctt ctctgccttt cgttgtggtc ttcgtaaccg
     1201 agggctgccg cgtgcgggtg gtttacccag tgtgaaaata ctttgtggac gtgccgtttg
     1261 atttcgtctt cctgcttcgt tccgactgcc aagccgttgg cggcgttgcg gataaagcgg
     1321 tcttccgcct gcgggacgtt ttggatgctg ccgtattttc cggtcagcag acggtacagc
     1381 tcgggataag cggtttcggt tacgcgcgtg cggatgtcgt caaacgccag ccagccggtc
     1441 gggatttggt cggacggaaa ccatgcggtg atgccgatgt cggtacggct taaatcgggc
     1501 aggcggttgc tgttgcccag ggcgcggtag aggtcgggga aggtgttttg tgcaaaggtc
     1561 gtgccgttgg ctttgagata gcctgcgggg tttcggacgg ctttgggaaa ggatacgatc
     1621 gcgccgacgg ggatgccgtc cgaattgagt tttttccatg cggaccagtt gtcgtttgcg
     1681 ctgctcgttt ggtggcgttc gtacacgtcg gacgtgtagg cgggataacc caactgcctg
     1741 caccagccgt gtttcgtgcc ggcgatgact tggatatggc aggcggtgtt ttcaacgggc
     1801 aggttggagc tgccgcccgc cgtcggcagg gaatagatgc cgtctgtttt gagggtgttc
     1861 aaatcgcccc ggaaggtttc gactttgaaa ttgccgatgc cgtatccgga cagtgtgttc
     1921 ggcttacctt cgatgtcttc ggcaaaacgc ggtttgttgg ctttgtggaa gatgtcgtgg
     1981 ttgttgtagg aaatgcggtt gtttgcgccg tgcaggcgga gggtgtcgtc gccgaagacg
     2041 atgtgggcgt tgtcggcatc cgcgccgatg taggctttgt ggccgccgtt ccagttcgtc
     2101 tggttggcgg ataaatggat gccgctttgg aattgggttt gggcggtaaa ggttttttgg
     2161 ccggtgatgg tttggtcgcc ggtggtaact acagccagcc tatttagtgc tgccagtaat
     2221 tgattaggct gcgacttatc cggctggata ccggccgcag tcagcacggc cagcagctcg
     2281 gattgcactt ggttgagcca ccacgcgggc aggatggtgc ccaattcgga cacgccgtcg
     2341 ccgtcgtgga aggtcttgtc gggggtttcg atggggtgca tggtttagtc cttatcggta
     2401 ggtaaatcgg atagcggtgt gggcgggctt gaggcggttg aacaggctct cgatcacggc
     2461 atcgctgtaa tcggtcagcc tgtcgcccgc cgccgagata ccggcgcgga atcgggtaat
     2521 gcggttgttg ccgccgcgca cgttaacgtg ccacacccac atgatttcct gcggcgcaag
     2581 acggtcgccg gcgcggttta caccggcgcg gaacggctgc ggttcgtcga tttggatttg
     2641 atagcccgcc gcctcggcca aacgcacaaa ataaggaata ctcaagccgc ctgtttcgtt
     2701 tagcttggcc atgacggcca acacacggcg ctggcggttt ttgcccgtac cgtccaaacc
     2761 taatacgcgc tcccaatcgg ccagcatttg gccggcgctg cgcgggtcga cggcatcggc
     2821 aacgctttga gccgattccg ccaccgcatc cagcgctgcg ccgtctattt ctgcctgcgc
     2881 ccgcacacgc ggggcattgc gggcatacga cacggggggc aacaggcccc gcaagatgtc
     2941 ttgatagctc atgacggcat ctccgttaca ttaatcgcgc ccgctttaaa ccactcgatg
     3001 cggttaaccg tatcggcggc acggttggcc gtcggcgcag tcagacggcg gtcgatcaca
     3061 ccatccacat tgctgatagc cgcctcgatt tgcgacacag tcaggccgtc gccggggatc
     3121 agggtgtcga aatattcttt tagggccgtc cgtatgcggc gcttggcctc gtccaagtcg
     3181 atgccgtcga gcttgacttg cacggtaaca ggcaccgccg ttacggttgg cttgagtacc
     3241 agcgcatttt ttgccgttac cgggcgcatc tcgtcgatat aagcctgtac gcggcgcaca
     3301 gtttcttccg atggcacacc gtcggcggag gtaatggcaa tatccaccgt acccaagccg
     3361 cggcgcagcg gataaacata tgcgctggtt acgccgtcaa cactcaacgc ccagttttta
     3421 tagtcgtaac ggttgccgcc tgcgggcggt cggcggatga tttccaacag acgcgccagc
     3481 agtgaggcat cgctttctcg gtcggtgccg ccttgtacgg taaggcggca ttcggtggcc
     3541 acaccggcgg gggcggccat cagttgcgcc tcgccgtcgc cacattggcg gccgcgcccg
     3601 gctcgtcggc gattgccggt atttccgccg tgccgccgct gccgataacg gcgcgggcgg
     3661 tagtgcggta aaaacgctgg ccgatacgca cttgcaggcc gtctgaaagc atggattgcg
     3721 caataccgct tacggtcagc gtgccgctgg ccgtggtagg attgcggcgg cgcaagccgc
     3781 gcatggaggc atgccgctcc aaatactcgc ggtcggcggt atcagggaaa atctgccgca
     3841 caatccagct ttgatgcgca tattgccctt cggcgcagct ggccaaacgg ctggcgtgca
     3901 cataatggtc gctgtcgggg ctgatatcgg catccggcca caggcttttg gtatcgcgca
     3961 ggatacgctc gcggatttgc tcaaatgtcg gcgtttcaaa cacgtttaaa acctctttaa
     4021 atcacgggca cttcgtggcg gtaatcaaac ccgcccgccg ccgtatccac ccggatatgc
     4081 aggatcaggc ggccgtcgtg cggctgctct gcgcgcacgg taatcttgtc ggcacgcccg
     4141 ctcttaacaa tcggttgcag tgcctcatcg gcatattgct cggccaacag gctgacccgt
     4201 tgcaggtctt tttcgcgctg caacaaatgc agcagcgagc cgagcgtttt atccgcccac
     4261 cagctgccca acggtgtcat caaacggata tacacggcat tttgcagcgt atcgacggtg
     4321 cggccggtat agtcgccggt gtcggggttt agctctttgt ccatgttggc attttgccgt
     4381 tttcagacgg cctcacggag tacacgggct tcaatcccgc acgcacaaaa aagcagcccg
     4441 aaggctgcca aaggtctgct tgtctatgcc ggttccgccg gtaaggtttt gccgccgatg
     4501 ctgtcggtat gcgggtgctg gcgcaacgat atattgccgg ccaccacgtc gccgtcggtg
     4561 ttaaagctgc cgcccgtttg gttaacatcg ccgctaaagg tggctccgtc gccgccctcg
     4621 acggccatgc cgccgttgcc gttgatttgg ccttgcgccg tcaacactgc actggtctcc
     4681 accaacggag cgttaaattt ggcatccgtg gccgcattaa cctcgtattg tttgcagtta
     4741 acccggtaca cgtcgcaatc ggcctcaatg attttgcctt gcttaatcac gatttttgca
     4801 ccctcatgat taaaaatcgc cgtctcgccg ggcttaaggt ttttgatgcg gtagctgccg
     4861 tgctggctgc acacaatcac accgtgcgaa gtattgccgc ccagcggtat cactaccgct
     4921 tcgctgccgt cgggcggatg gctggcaaag ccgtattcct gcaaatgttc aaggtcttgc
     4981 agggtttcgt cggccaagcc gctcaactgc acgcgctgta tcggctcgga cgacaccacc
     5041 agcgtgattt ttccccgaaa ggccgcgcgc agggtttcgc cgatattttt agcagtttgt
     5101 gccgtttttt tcgccaattt actcaaactc attcaaacac cgccgtttct gcttgttttt
     5161 tgccgccttt tttgccctta tggctcacgc ctttgcgttt gcctttgcgc ttgcgcgccg
     5221 cctcggcctt tttggggtaa gcgtcgggtg tccaaatacc gtcctctttg agccgcagct
     5281 cggtttgcgt gccatccatg cgggatagca taaaccgccg ccccatcaga aaaaacaccg
     5341 catcgatacc gtgctcgtcg tcgatcacat gcacacgctg gccaggttgc cacaatacgc
     5401 cgtcgcgggt tttatggccg cccacggtta tcgtgagtgt aaatccctcc agccgccagt
     5461 cggccagctg ctttttagcc tgcttttgca atgcggccaa attgtcggca tcggacacca
     5521 ccaccgtttt agggcggtgc agcgtcatcg tcgggtcttt gtacacccac tttaaatcgt
     5581 gtttggcgct gtcgccgctg cggccgtgcg attgcgccaa aaaagtaacc tcggaaaagc
     5641 ggttgtcggt atcccactca atgtccatgc gctcgatatt gcagcggctg tcggtgcggc
     5701 tccaacacaa tgtcgccacc ggcgggctgc tgtaatccgc accgcccacc accaacgtgc
     5761 cgtccggctc cagccacgga tgcagcccga ccgagttggc aatatgggtt aatgcctgcc
     5821 atacggtttc gcccggctcg atgtcgattt tgtccaaagc ggggttgttt tcggccttaa
     5881 gcaccaccgc tttaatctgc ggccacggcg cggccagctt tttggctgca tccaataccg
     5941 tcatgccctt tacattgagc tgcggcgcgg agcaatccac caaaaaaccg gccaaatcac
     6001 gcccgctcaa gctcaactcg cggctgccct tgcttttgcc gtggcgctgg ctgccgatga
     6061 tgcccgtcat cacgatttgc ccgtctatca ctacctcgca gctctctccg cttaaatcgg
     6121 gtatggccgc ctccggcccc aacctgccga tgacaaaatc gaagctgtcg gcagggatta
     6181 aaaagtcgct gtcgatgtcg tagcgctccc agtggcggtg ctctttaccg cccacgcgca
     6241 ccgacacggc atagccgtat gaattatttt gcatagctgt tgaccaaagt gccgcgcttg
     6301 ataaacgcgg ggtggtggat atggggattg agccgcacca gctctgctgc gcgggccata
     6361 tcgccgtaaa actcgtgggc gatttggtgt atcgtaccgt cgattggggc ttggcgcaca
     6421 atcagcggcg gcttttggtt gatggccgcc gcaaccaacg cattcagacg gcctgccgcc
     6481 gcgcgcaggg attctgccgt ttggtaagcc tcggtataca cggcgttggc cgtcagccca
     6541 ccagactcgg cagcagccgt ctgcaccgcc cgcaaggcgg caatctcggc ctgcatacgg
     6601 cggcgcatgg cgcggttaac ctcaatcaaa tcgggcgcgg tcatctcttc gccatgcgcc
     6661 tcgattaatg ccgttgccac cgacaacagc gatgacgtgg ataacaggcg caccgcctgc
     6721 gctaccggct gcacctgttt ggcggttaac cggttcaggc ggttttgcag gccgtctgaa
     6781 aagcggccgg tcagtaaatt atcagggata gcggcggcac ggtcggcaac agccacagcc
     6841 ccgtcaaacc gctgtcgcgg cgaccaaccg gcatggtgca tggcattatc ggccaaaccc
     6901 gcctcacggc gtatgccagt atctaccatg accgatatat ccgcaaacag cttggccgag
     6961 ccgtttttaa acgccgctgc gctgtatccg ccccgatcgg gaaaggcaat tttgtccaaa
     7021 tcaaacaaac ggcgcaccgc accaaacgta cccgatgccg cactccaaat gcccagcgcg
     7081 ctgccccata aagccgatac gcccgcatcc accgccaaca ccgcatcaac aaagccgata
     7141 gccgcctcgc ggtaggtgtc gatatcagca atcaacgcct caagctcgac caaaaaggcg
     7201 ttttcaaaaa caaagatttc ctgcgcttcg gccgcctcgc ggaaagtaat atcgatgccc
     7261 gcataatcca cataatcggc ctcatgtcgg taactccatg atgccgcaat catgttgtgc
     7321 atccgccccc aaacagggtg caccagcacg ccgccgcccg gctgctccag cgcatccagc
     7381 agctttttca gacggcctgc atagcccttg ccccaaaaca ccgcattaat ctgcacctgc
     7441 cgcccggtca tgcccatgtc ttcaaggtcg ataccctgca caaacggccg cgcatgctcg
     7501 gccaatgcct tgccgttgct ctcgtccacc acctcaatat caaagccgac gcccttgtaa
     7561 gatgcgtcct gcaataaggt atgccatccg ctcattattg acccgctcca cggccgaaca
     7621 tggccacttg ataccgcgat acctcattcg cgataacacg tccgtcgata ttcaggctca
     7681 cattggtatt gatggtctga cttgccgacg ccatcgcact ttgcacttgt gccaaacctg
     7741 ttgtaactgc agccgtatcc tgcgccaatg ctgcctgata cgccgccgtc tgctgctgaa
     7801 tggctgcctg atacgccgcc gtctgagttg aaaacaacgg agacaacatc ttatcggtag
     7861 gctgcgctga cggagcagcc aaatactgag ggacaccacc ccgcgcctgt tcccgcttcg
     7921 gcgcaggttc aaatcggata ccgttgtttt tcagacgatt aatcatttca ggagttgtct
     7981 tggtaccacg caaacccttt ggcaatgtgc cgtcacccaa agactcggaa tacagcaaca
     8041 tacctaacaa acccgcccgt ttaactaacg ctggattatt catgagcccg ctaccggcag
     8101 attttcccca tgacagcaac ttaccgcctg ccgctgtggc acctgctgcc acgccgcctg
     8161 cggaagcctt accccatacc aacgctttac tacctacatc tttcagaaag cctgcacctt
     8221 taccgccacc ggcggttaat aacattgcgg cagacgccgc tgttgccgcc gtcgtcaatg
     8281 cttgcagggc tagagtggca ttagggtatt ccgctgccag ctttttaaac gaggtttcca
     8341 tatccaccaa tgttcccgtc agactttccc gcaacattgc cagcgattcc tgttgctctt
     8401 gttgcgccgc tgccgacaac attcgcgcct cgttgttctt agcaattttt ccgttatcca
     8461 acgttacgcc agccaacgaa gccatatatt cacggatttg cgtcatatcc gttgcagcca
     8521 gcaaaccttg ttttgcctgc aaatcaggca gcagttgcgc caaaagcgcg cccttaagca
     8581 tatttgcctg ctccgccgcc gtcttatcgc ctgcagccgc gcgtttctta taatcttggt
     8641 attgcttatc ctttactagc atggcatcgg caagacggga caacacctgc actgcgtttt
     8701 cgccgttttg cttgccttgc acaaccgagc ctatccaatc gacacctttc ttcgggtcat
     8761 ttggatttgc catcttcttc aaacgaccta tcgtgtaagg cgacagagtt ttactcaaaa
     8821 gattttgcac attagtcgcc gcttcggcag gactgcccga tttattcgcc gcagattgta
     8881 agagtgagag caggtagtcc aaaccgccga caccattcat ccctgcctgt tgcgcggcag
     8941 ggagcaggct cggcagctcc cgaaccatat cccgcacctc gaaagtgccg tctaaacccg
     9001 attgcaagac gtgctcaagc ccgagttgca ggtctttacc gctcatgccg ccatctttca
     9061 gggttttaat cagttttgcc gtatcctcgc cactgccttc tgaggcaagt gcaaaagcat
     9121 atgccgcctg cgcttcattc ttggtttggg caaaattcag actggtggtc atcatgccgc
     9181 tgattaaatc caaagcctta tcgtgggtcc cgccattttt ctcgacaagt tcaagtgcca
     9241 aatccttgat ctgttgcgca ccttcagttg caatccacgc tgccgattta ctgttatcct
     9301 caataaatgc ctgtctggac acgcggttga tgttctcatc aagctgcttt ctgttgtcca
     9361 tagcaggctt aagcaccgta tacgctgccg cgccaccagc caccgcagct gcaccgaatc
     9421 ttccgatttt tcccatcttg tccgcaaatc ccgtgccctg tttcagttcc gcgttcagct
     9481 cgcgaattcg gttacgcgta gcgaccgccg cccgtgccaa atcattttgt gatgccttgc
     9541 cgctgcgcgc caaacggtta aacgcagcct gtgtcagcat gatttcgcgt tgaatctgtt
     9601 tttctgagcg gatgccggtc aacgcataag tatggctttg ccgttcaagt tgcgcccgcg
     9661 atttcgcggt acgatctaat tgtcgttgag tatcagccag tagccgtctc gctccgtcat
     9721 ctcgggcggt taacaccaac gacagtttca tgttcccgtt tgccataaaa agcagccttt
     9781 aaacgtatta actcaaggtc aattatcgtt taaaggctgt ttaagggagg cggtatgggc
     9841 ttcaaccccg ttttcgtgct ttatttgttt gttgcgttat aataccagaa tgataaccat
     9901 tttattcaaa gggatatttt atgaatatga aaaaattgat ttccgcaatt tgtgtttcaa
     9961 ttgttttatc agcctgcaac caacaatcaa aaacggcaca agccgaagaa cctgtccaaa
    10021 gtatccaggc tgctgattgt accgccccaa tggacatcac agttgaacaa tatctcatca
    10081 atttggagca agcatttaaa actcagaacg tctcaacaaa aatccataat aaaaatattg
    10141 tcaagaccga ttgtggttat gaccttactt tggtaatgga ttttggggcg attgcgctca
    10201 aactggacga gcagcaaaaa attagagcta tctcagtagg ctacatttta aaaaccgacg
    10261 gagagaaagg acaaaatcta gtcaataatg ccataaatgg attacacagt attcaggcag
    10321 ttctgtcttt aactaccaca gacaaattgg gcgaatcgga agcaggaaaa caacttcgtc
    10381 aaagaatcca atcagacagg agcaacagcg caaaaagacg ttccggcaga tggtatttta
    10441 tatagcgttg tttttgaaaa agaaacaaac accattgcaa taatcggcag aaaacaaccc
    10501 taaccgtcaa ataaaaaaaa ggtcgtctga aactcagacg acctttttat tttccctccg
    10561 gctttctcag ccgtttcgac acaatcactc cctcttcctt cggcgttttt atgcccaggc
    10621 tcgacaggat gtcttcaaac catgccgaca gctcggcgtg gcacatatcg cgcactgcgt
    10681 ccgcccctat ccccgccttt gccatcagga tgaccgcctg acggtagctt ttgtgtgccg
    10741 tcaggtagct gcgttttact gctccgccgc cgacggcgcg tcggggctcg ccgtagcggc
    10801 ggacggtttt aggcacaaat cctcctgagc cgccatcacg gtatggtagt cttcggtaga
    10861 gaggttttcc atcagccact gcgccgtcag gatgtcggat gggatacctt gggcttcaat
    10921 ctgctgcgac cagtaggtca gcgtctctag gacgtcgcgt tgcagcagtt cggcttttgt
    10981 ggcgttttcg ggcagctcgg gcaagtcatc aatcagggcg aacgccgcca gttcgccgcc
    11041 gacggtcagt ggcttgaggc gtaattcaga tacgactttg ccattgtagg tcagcccgtg
    11101 ggtcagtttg acggtaatca cgcattactc cttgattttg tgcaaagcaa tcatctcaat
    11161 gtcgatgcgt gcctcgttat cgacttcata ttgctcgctg gtatcgacgg taaagcagtc
    11221 gaggtaggaa gtgcggcgac cttcgtcgtt gatggggtaa atcgtgattt tcgccttggt
    11281 gatgttgtcc cagtcgattt ccgtaccgtc gatcggaatg gcggcggtaa cgcttaattt
    11341 gtgttcggtt acgccgtcac aataaccgtt gactcggccg ttgcggttca tcgttttgac
    11401 cggcttgcgg cctgtagtgg tttgcggttt gatgctcaca atctcgatat cgcggccgtt
    11461 cacctccata atcaccgcgc cggtataggt agcgtcgctc atgctttatc cttttttaag
    11521 gtttcagacg gcctttaaac ctgttttaaa cgccgtctga aaagggttac aaaatcaaat
    11581 caatgcgccc ggcaaagacg tgcaggccgt tgaccacatc ggcggggata atggcattaa
    11641 cacggttggg gtcgttttgc gcacgcgcca ccaccagctt gcctttgttg gcctcggcgt
    11701 tttcgatgat ttcggcttgg tcgagcttaa tcagcacgtc caaaatctcg ctcttaacct
    11761 tgggcagcag gcggtcgctc aatttgtcgc gcggaaaacg cagggcaatg cgctctttaa
    11821 cgctgcggcg cacataatcc agcgtgcgaa tggtggtaat gtcgagtagt gccgggtcgt
    11881 cggtgttgtt ggccgacttg gtataggttg atacggcacg cataatctgc acgcggttgt
    11941 tgaccgctgt gagcggggtc aagccgttgt acagcgcatt gttgcattct gcaaaccacg
    12001 gccattgcgc atcaggtgta acggccagcc ctttgatttc cagcgtgttc agcggcttgg
    12061 cagggtcttc ttcaaaggcc aacaccgccg cataacctgc ggcgatgatg ccgtttggct
    12121 ctaccgcacc tttgtaccaa gcacaggtaa tgcggccgtc gttgattttg ccggtagcgg
    12181 tggtggccgt gctcaaggcc gcactcatac ccaatacgcc gatacagccg cgctgctcga
    12241 tggcgttgaa tacgttggta atatggttgc tcaaggcttt ggcgttggcg tcatcgctaa
    12301 acgggctgca aataatgtga taatgcttgc ccgccacttt ggacaaggcc gtggcaatgt
    12361 ccgcattttt ggcaccgccg gtaaagacat tggcttgata agtcaggccg gtattgccgg
    12421 tgctcacggt taagccgctc tcgttgccga tctcgccttt gtgtttggcc gtcagcgtaa
    12481 cggctacgcc gctgccggat gcggtaacgg ttacatcggc ggcagtgatg gcggttttca
    12541 gacggcctgc cactgtggcg gcggtctcgc cggtgttaac ggccgtgctt acctgcttgc
    12601 cgccaatcgt gatttccacc acgcccggcg cggtggccgt gccggaaagg gtaacggttg
    12661 cggttgcctg cacgcctgcg ctgtggtcgg caataccgat aacggtcaaa tccaaataag
    12721 ggttgttggc aaatgcttgg cgcaccatca aatgcgccag cgagccttgt ccgaacaaat
    12781 cggccgcctc ggcatcgcta aatagttgca ccggctctaa ggcgggctgt atgcccgcgg
    12841 tcagcatggg tgcaaccatc aatacctttt gcggattttg cggcaaacct tgcacggcat
    12901 tgcgggtgtt aaattcaata tactgcccgg gcacgcggat gctgcccgga atcgtgtcaa
    12961 aatcaatatg gggcatcatt actctccctt agtattgcgg gttttggtat ttggggcggc
    13021 atcctcaacc accaccaaat cgccgtcatc aatcatgcgg cggtaataca ggctgttgcc
    13081 gtccacctcc accggctctt ggccgatata ttcgtgcggg ttgtgttcgg tcggcacacg
    13141 caggccatct gccgccgtta ctttgatttt gctcattgct tatccttaag ggttaggttt
    13201 acaggtattt catcggcgga ttgcgggtcg taaattttgc cgtccaaccc ctcgaaatca
    13261 ggccacggct cgctcaatgt accctgatac ttggtaaaga tatggttggg gtcgtcggga
    13321 ttgtcggtgc gttcggggta gcggtcattt tccaacccgc aggtgttaaa gcggatggca
    13381 tactcaaccg catatatgct tactgcggcg ttttgcacca gcacatgatt ggcaatcgcg
    13441 cgcaccgctt tgggcaccaa gccgcggcta tcggcaaaac cgagccgctg gccgtcaagc
    13501 aggcggcgaa cagcgcggat taaatcgttg ctgccgattt cgcggctgtc gatgccgcct
    13561 tgccgctgcg cctgctcgtt gcgcagattg cgggccgcca ccatcaccac aaattcggcg
    13621 gtatcctgat aacgtccgca tacgccgccg gtgctggcag gctcaacttt gctgccgcca
    13681 tacgttaccc aaaccgcagg cagcgtatgg atttgccccg ccaaatcgtc ggcctcgccg
    13741 ttgtagcttt taaccgtgcg caccatgcga cccaagcccc gtttcagacg gtctgttatc
    13801 gcttgctcaa tatcagtgat cacgcccgaa caccttattt ttaccgttta caaacacaat
    13861 accgtcttcg cccgcggcca cttcttcgcc gctatcatcc acgcccagct gcacttcgcc
    13921 tttggccata gcacgcagca ggtcgagcac gtcgattttg tagcggttgc ggatttcgtc
    13981 ggtaatcaac acgccctgag ccgccgtcag acggtagcgg gcaatgtcgc agcaaaggcg
    14041 caccaagatg ggcggcagat cctcaaaagg tcgtctgaac cgccccagat acgcgtcgat
    14101 ttcggcagtg gcgtccacca gcgcggtttg tgcgacctcg cggtcaatca gcccctcgtt
    14161 gttgcggtcg gtgagctgca agacttccag ctcaccgaaa cgcgcaacca tatcctcaac
    14221 cgtcgcgtat gccattactc gaccgccttg cgttgcagca taggctcggc gcagattgcc
    14281 ttccacaccg cttcgccgac ttcggcgcgc ttcacttcac gccagccgcc gtcaaacagc
    14341 aggccgccgc gccaaaattc tttgccgtct gcgccggtac tgacgagcat cacatcgcgg
    14401 ctgtccgcca aagcgtcggc ggcgcgttgc gtatgctgca ctttgagttc ggcaagttcg
    14461 gcggacagtg cctttttgtc gtcttcggct ttttccaagg ctgtggtcag catttcgaca
    14521 tcgtttcggg cggcggcaag ctctgcctgc acggcgtcca attcggcttt gatgtcttca
    14581 aacgacgggg cggcggtttc ggcggtttct ggtttgttgt tggtttttgc catgatgact
    14641 ccttgtttca gacggccttt aaataggtgt taaaggtcgt ctgaaaacgg ttcggggtta
    14701 caggtggacg caaacgtgca gtttcagacg gcctttgaag gtattggtcg tgccgttgat
    14761 tttgtcggct tccaataatt cacgggcttt gtcttccagc tcgggcggaa cgaccaagag
    14821 gctgggcttc acattcaaca catagccacc gtcggctttg attttctgca ttttgacgat
    14881 aatggcggcg aggttttcgc gggtcagcgc ggttttttcc gccatgtgca tcagttgcca
    14941 caaaccgaaa ccggcattgc agcggcggcg cgatccgtac aggtattcgt cttccataaa
    15001 cacgcggtcg gatttggacg ggtcgaattt ggtttcaaac tcggagtcgg tgcggttttg
    15061 gaaaatcagc ggcttcaggg tcttggtgtc atcgacgacg tagaaggtcg gcgcgtcgtt
    15121 gtccgtaccg gtcgtcagat tggagtgcgg cgtattctga cccgtgccgt ccgatttctc
    15181 gtaaacgggg tggtcggtat cgaagaaata ttggccgtca taaccgacag tggttttacc
    15241 ttttttgagc agaccccaca ccagcgtatc gggcagggcg gcggcggact cgcccattgc
    15301 cgccatcatc gggcggtaca tgccgacttg gtcgtcttcg atgtccgtac gcgctacgcc
    15361 gacggttgct tcaaactttt tgttgtcgag gctcatcgcc tgcttgttca ttttttcgat
    15421 ttggcgcgag ccgacccatt cgcgcatttg ggggaatttg ccgagccacg cataagtatt
    15481 ggttgccgta ttggacggaa tggtcatcgc aacggcggta tagtcgggct tgacggattc
    15541 caaacccgtt tgaaattctt tgcggaatgc tgccgtgatt gcggtcaaaa tcgctgattt
    15601 gtccattact taccttcgct ttctttgatt tttacaaatt cttcgccgga catgcccagc
    15661 atttttgctg cggctgcctc ttccgcagtc agtgcggcga cgcgttcgtc gggtgcttta
    15721 ccgcccgttt gcgagcctgc cagtgcagcg accggctggg cgttttcaat aaagccggtc
    15781 aaaaatgcca agccgcccgg ctgtttcaat acgccttctg cccactcctt ctgagcaggc
    15841 agcaatttgc ctgaagtcag cgcggcggta atcaattcgt tgcctttgtc tgcttcctgc
    15901 ttggcagtca gcgcggcgac tttgctttgc agctcttgaa ccactgagat aggcgcgtat
    15961 ttagtcaaat caggcttggc ggtttgcgcc gtcaatgccg tgatgcggct gtctttttcc
    16021 gccagctgcg cgaacacgtc ggcagacaat gccacgtctt tcggcttggc ttccacgagc
    16081 gcggacaatg ccgccttcag ttcttcttcg cccgcatcag gcagaccgaa cagttgctgt
    16141 aacaactctt tcatagggtt ttgctccgtt tccgatttta aaatttgcgc cgacgctgcc
    16201 gccagcacct cgtccatacc gtccaacgcg gggaaatttg tcagcgcggc gtgaaaaatt
    16261 ttgcttacat atccctttgt gtcataggaa aacacagcag agatgtagcg atactctttt
    16321 gcggcaattg ccgcagccgc cttgtccgtc cactccactt cggcaaacat gcctttaggc
    16381 gtgaactcca gccaacgcat ccaaccggcg gcaggtgcag gttgtccgtt tttctctttg
    16441 tagagcgtct ggtgttcata atcgacaacc aactgattgc gcgagctgtt ggccaacaac
    16501 gcgacatcat gaccgttttc ttcggtcaga taccacgcag ggacatcagt cggacgaccg
    16561 tctactgcgc gaaattcgcc atatggcagc agttggattc gcccgtcttt tggctgcacc
    16621 tcgaaactgc acacggcaag tagggttttt tgtgcatttt tggacatgtg tacctctctc
    16681 aatacggtca ttttgcctat ttgaaaaaac aacaaagagt aggcgtgctt caaaccctcc
    16741 cgccattttt ttaaaacctg tccgcgcgat acacaattaa tcgttttcag gggcttttta
    16801 gaagcgtcta ggattgattt ttatatcttg ggcaggggtt tgtattaccc gcataaaaaa
    16861 acgcgctaaa aagcgcgttt ttgagggttt tataaattca cggtatcaga cccgaaaaat
    16921 aatcctgcac atcgtccatc aaagcctgtt tgtcgtcgtc cgtcagcgtc aaaaattccc
    16981 gttgcggaat ccgaactttg cggttgcgcc ccgccatacc gccgaagttg tggatggcgg
    17041 catagacgat attcgtaccg acaagggcgg tatcgttgtc tgacagtgtg gaaaaactgt
    17101 ctttcagacg acccgaatcc gaaagcggct tgccgtcgcg gtattttagc cccaaccatt
    17161 tcggacggcc tgcgtagcgg aaattgagct tgaccgccgt gtgcatggtt tcggacagtc
    17221 ggcgcatcag caggtagcgg ttttcgatcc cgttgccaag ccgctcgatt tggtttagga
    17281 cgacaaagat attgtctatt ttgacatcaa tcatggtatt atcctgccta ggctactaaa
    17341 aaagcggtga atttgtctgc cctccgcagc ccttatgcag tcctcggact gggattggta
    17401 tccgttacat aagcgagagt gtgtcgggat tgcagtccga cttagtagcc ttttttcatt
    17461 tcatagcgtt tcttactttt cacaatttct ttttcatccg ccctgcgaaa cgaatccaaa
    17521 aaaatcgaat cgtactgtgg cagatatttc aaaactgcca tcaatctgta tttttcgttc
    17581 ccctccaacg gttttccgag caaaacaaaa ctttcttttc ctctgctttt gtcataaaaa
    17641 atatattcgg gctcatgaat cagatcgggg agcatggcat ataaatctgt tccaaacgat
    17701 tgcccctccc gactgtccac ctgtttgacc aatgtatcat cagacagcca caccgtcgct
    17761 cgtgtcatac ctgccaattc ttgcgtttcc ttgctcaata cacccgcagc aaatttaagc
    17821 tgtcttgata gcgcatttcg gattttgatt ttctgctctt tatcgggctt gccatcaata
    17881 tccaaacgtt gcttgacttc ataaaactct ttttcaagct gtttaaagct ggttttaaaa
    17941 tccgcaccac ccatttccgc tttggcaaat tgatgcgcca acgcacggtc gtacttgtct
    18001 aaatcggggc ggtagttcat tcgtccggcg ttgtaatcaa atcctcgatc ggtcgtgtac
    18061 agactgccat ccggtgcttt ataggcaagg gtcagataag tatcgccttt tttgttgtag
    18121 attttatggg tctcgactag attgtccgcc gtgctttgcc cgacaatccg cccctggcgt
    18181 tccacatccc gctccgacag cgcgatgacc gagcaacggc agttgtagcc gttgggcggg
    18241 taaaacgttg cccaaaacgg gtcgtcgtag cggtacacca gcccgtctat tgccgaatgc
    18301 gccggacggg tgcggctgtc gcctaccgcg tcatacatcc aatagggccg tgcatcaata
    18361 tttgccatat atccttgata ttgaccggcg ttgtaggcag tttgcatgtt ggtacggtaa
    18421 atcgtctcca acctccgcgg cgaaccgaat acctcgccgg tggctgggtc gatgatatcc
    18481 ttaccgttat gcccgttcgg atgcagccag cccttgttgc cgagcagatt caagatacct
    18541 tttcgccaat cgtcaaacga ctgtccactt tttgccgatt caaccatcga agttttgatg
    18601 tcgttgagca tatccaagtc ggtcatgcgg gcaatcgtat agactttggc aatttcggag
    18661 gctgtcagat tgcggtagct ctccgccgta acctttttac tttccagcca ctcgattgcc
    18721 ttttttggcg gcagacttaa ggcaaatccc aaatcaggcg cgggcatggt cttgtcccaa
    18781 aatatcgctg ataaacaagg cctgctgcat ataggtacgc agtttcgcgt tgtccaaatt
    18841 cggataaagc gcattcagtg cggcatctgc ctcctcgtag ctgttgcaag cattaagtgc
    18901 ggcaaccgcc tgacgcacca tcgggttgag ctgagaattg aaatcgggct caaccagcgc
    18961 gtcatccaac gcgccgtcca atatttcctg atgcctgccc gtagccttag atggtacggt
    19021 gtgggcggat aaagccgcca atgcagttct gtttatcgga ttgtccggta cctgccgcac
    19081 caacacagcc tcaccctcct gcacatctgg aatgaccagt ttgtcgcgca cccagctttc
    19141 ggggatttgt acgccgacat ccaccagttt cgggatagcg tcggcaaaga ccgcgatgtc
    19201 tttcggctcg cgcgtgtcaa attcaaattt cggcacgcgg tttgggtcgg cattgggata
    19261 gttgatttgc aggaacggtc cgatgatttg gcttgtgatg gtttgcgcca cctgttttgc
    19321 gtccgacacc agcaaatcgc ggcgtacctc gttgtggata ttgcccagcg cgttggtgct
    19381 ggattttccg tccgcaccgc tggttagcgt ttgccccaaa atcagccgcg ccgccgattt
    19441 ttcgcaccag tcggccatct gcaaaaacgg attgctggtt gccatcgtac cgcttgcagc
    19501 gttgtgcagc tcgatttcca taccttctgg catgatgcct gccgcgttgt gaccgatttc
    19561 cgccaccgct cgaagcaggg tgtttttttc ctctttggtt gcgcccgcgc cgtatttgcc
    19621 gatacggatg ggcatgccgt acagctccaa aaactcggca aaatcgtgga cggcgtagtg
    19681 tttgaacata tacagccagg aaagcgtgcg gaaaagcccg ttgcgcgcct gctggacgct
    19741 gcgcgatttt tgggtatgaa cgacccagcc cagcggccac aacgcttcgc cttccggatt
    19801 ttcgcgggta cgcagcagca gcccgttgtc tttgtcccat ttgaaccagc tttgcgggcg
    19861 gtggataaag tttcggggta ggtaaaggcc gtctgaaaat acccactcga cctccaacgc
    19921 agaaaatccg tgccctaccg cgtccatcaa atccataatc aggtcttcga gggtaggcag
    19981 gctgtccatc atttcgtagg cttggtcgga cagcttttct tcttcgggcg tcgcatttcg
    20041 cggcggggcg acgcgccagt tgagcgtcag cagcgcgcgt ttgcgcgtcc ccatatttgc
    20101 cgcgatgtcg ctgtcgcgct cctcaatgtc cgcgaaaagc tcgtgttggg cgcggatgtc
    20161 gccgctttcc gcatcctcga agagggcccg catcttttgc ggtgtaataa aattggacgg
    20221 atgctcggcg ataacccgac cggtcgccgt aatttgagcc acgtccgtct gcaatgcagc
    20281 ttcgggcttt tggattttag ttttattgtt cttttttgcc attatcggct ccatttactt
    20341 tttatctcgt catcaaaatc gttatcggta gggctttgcc attctatcgg cacacaattg
    20401 gccaccgccc ccgaccagag catatgcact gcatcaggac catcatcatg atcagccttt
    20461 ggaaaatggc ggaactgctg tatcagcgtc tgttggctct cattcaacag aatcaaaccg
    20521 ttcgccatgt gaggctgtaa agtctcaatc cgcaagagct tgtccgatac cggcttgacc
    20581 gcccgcgccg ggacaggtat tccacgcgcc gcgctgcgct tgaccagctc atctttcaaa
    20641 aattcctgaa actgaaccgt ctcaacaaac cacagtttgc aacgatattg acggtgcaat
    20701 ctgataacgt cctcaataat caaatcaggg agacgttttt taatctgagc ttccacgaca
    20761 tacagtttgc cggtttcacg ttgataaccg ccaatgataa tcgccgacgg gtcacggctc
    20821 gcccccgctt tacccagcga cgggtcgagc gcaccgaaat acaccaaatc ggacggcagg
    20881 tcgttccaaa acttcatcga cttggcaaac ggcgcatctt cgccgctgac cgggtcgttt
    20941 tgatactcgc tgtcaaatgt cgcatgaccg tcacgggcgc ggattttcat cagcgcgagt
    21001 acgccgcgag ccgcccagct tgtttgcgcg ccgcgctcca tctcgtcttt attggcgaga
    21061 taaaacgcct cggccaccgt ctcgccgtcg tttcggaaaa gttcctccca tctgtcccac
    21121 aagtccatgc ggtcgggcca gcgtttcatc gccttaaact taacaccccg ccaaaacgga
    21181 ttattcaggg tgcggtttag cacgctgtcg taatgcaaaa tcgtgccgat ataaatcaca
    21241 tcgtatttct gaccgacacc gcccaaaggc aatacagtct tagtcagcca cgcattgagc
    21301 ttgtcgcgct gttcggggtt gcggacttgc tcgtcattct caatatcgtc caatatggtc
    21361 aggtcaggac ggtaagggcc gtgacgcaaa ccgcgcagct ttttaccgct accggccact
    21421 tggactttaa cgtcattggc cgtcgcaatc gtaccggcct gccatacgcg gccctgcccg
    21481 catacttccg gaaagtcggt tttcaagcgc ggattaaatt ccaattccgc cttgatggct
    21541 tcgagcatcg ggtatgcctg atctatgctg tccatcacaa taacggcata atgtttttgg
    21601 cctgtcacaa tacaccacag cgtaaacaac tgagtaacct gcgtcgactt accctcgcca
    21661 cgcggcgcac ccaccgcctc attttcccct ttgggggagc ggataatctc cggcagacgg
    21721 ctgaataaaa acgcatgcag ttcggatttt tcaggggagc ggatataatg cggaaagtag
    21781 gtgttgacga aatactcgta accgcctacc gggtcaaaca ccttggcacg gcgtgcagca
    21841 atagccttgg gcaacgcatc aaagccgtcc acttccgctt cgatgacttg gcgcaaactg
    21901 gcggccagtt cggcaaggga tttgaggaat tcttttgttt tcatgagtat ttataatgac
    21961 tggattcatt tctaacgcat ttataggcct aaaagaagca ggatcacttt taaaagggtt
    22021 taaccagctc aaaacagagg cagaggtagc gcaaaaaacc atcgaactta atcaaatcat
    22081 tgctggtatt caaactgatt tatttgaagc ccaatcttct tatacggcgg caattagccg
    22141 tatagatgag ttggaaaaag aactggtggc agtaaaaaat tggtctacag agaagcaacg
    22201 ctaccaattg tatgaacttg ctcctggttc tttcgtctat cgattgaaaa cagagatggc
    22261 gaacagcgag ccaattcatg atatttgtcc ccaatgttac gagcagggtg tcaaatcgat
    22321 tcttcaattc aatgggtatg aaggtgcttt tcataaatat tcctgttccc gttgccaaac
    22381 cataatattg ggagagcgtt taaagtcaga tgttgaagta ttttcagtag gaggatcacg
    22441 ttatgggaga ttgatagacg gctattaacc aaacttcttc tccacttccg ccccaaacgg
    22501 ctccaatacc tccacaaagg caggcaaatg tttggg
//
LOCUS       DAXISH010000031        22346 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.031, whole genome shotgun sequence.
ACCESSION   DAXISH010000031 DAXISH010000000
VERSION     DAXISH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 22346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22346
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.031"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            1..100
                     /locus_tag="ACFOV4_001174"
                     /pseudo
     CDS             1..100
                     /locus_tag="ACFOV4_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805306.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            complement(121..1035)
                     /locus_tag="ACFOV4_001175"
     CDS             complement(121..1035)
                     /locus_tag="ACFOV4_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFC7619194.1"
                     /translation="MDAVQLKSFVAVAHEGNLTQAAKRLFLSQPAVSAQIKALEEYVG
                     TPLFRRTGKGMVLTRAGEILLPEAESLLQYKHKLEHFAKTLAGDYSEETSLGIIHPID
                     SAKLVALTDNIGQTAPKTRLHIQYGMSGEILSRIQHKTLHGGFILGNAAQRGIRSVFL
                     QNLTYALICPQSQYPHLTRSLPQSLQECVWIEMSGVSGSRKHLHQFWRSNRLSPKKQI
                     LCDYPQTIIDLVAGGIGVAMVPGNKAEAAAKEGAGVAIIESCRHSMPLNFIYAEEYED
                     NPHVSLLLECIEKVWGVQAVQPPVVSDN"
     gene            1291..2760
                     /locus_tag="ACFOV4_001176"
     CDS             1291..2760
                     /locus_tag="ACFOV4_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3360 family protein"
                     /protein_id="HFC7619195.1"
                     /translation="MEKHNGTYRDLHRPASEFATRDEYLEHELQIMQPKRWRPNLPFR
                     DYRFEWEDLIPAMAGTIGKVVMVGAVAAAFAAPLGLPDSFVLENVRYELLIAAAFILL
                     VSGFFLPGANLPGTHGPLIPMIPIVVSAGGHPLAFGISIAVLGLLMALFRGGSIMAKL
                     TSNGVCGGLLLYLGFIGTTGQVKKLFSWAGGFNMPYIAFTVIIVTIVMYALLEHWKKR
                     WLAVPLGCLIAGVVAFALGAPFEFHTAPGLPPMSPAYWWGENSGWHLGLPTAESFLVV
                     FPFAVLAVAMWSPDFLGHQVFQKISYPEKTDKVLMNIDDTMTSCSVRQAVGSILGGAN
                     FTSSWGTYIVPASIAKRPIPGGAVLTAVLCIIAGLWGYPMDLAIWQPVLSVALVVGVY
                     LPLLEAGMEMTRKGKTTQSAAIVVFSSALVNPVFGWALTMLLDNLGLIGCKERSAQLG
                     FAGRVLIPAVGFLILCVAMGAVGMLPGIPPFLEHFKSLG"
     gene            3012..3383
                     /locus_tag="ACFOV4_001177"
     CDS             3012..3383
                     /locus_tag="ACFOV4_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619196.1"
                     /translation="MNKTLSILPVAILLGGCAAGGGNTFGSLDGGTGMGGSIVKMAVG
                     SQCRAELDKRSEWRLTALAMSAEKQAEWENKICACVAQEAPERMTGNDVMQMLDSSTR
                     NQALAALTAKTVSACFKHLYR"
     gene            3456..4865
                     /gene="thrC"
                     /locus_tag="ACFOV4_001178"
     CDS             3456..4865
                     /gene="thrC"
                     /locus_tag="ACFOV4_001178"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HFC7619197.1"
                     /translation="MKYISTRGETAHKPFSEVLLMGLAPDGGLMLPEHYPQIGRETLD
                     KWRGLAYPELAFEIMRLFVTDIPEDDLRDILNRTYTEAAFGTKEITPVRTLSDGIKIQ
                     ALSNGPTLAFKDMAMQFLGNAFEYVLNKEGKKLNILGATSGDTGSAAEYALRGKKGVN
                     VFMLSPDGKMSAFQRAQMYSLQDGNIHNIAVKGMFDDCQDIVKAVQNDAVFKEKYHIG
                     TVNSINWGRIVAQVVYYFAGYFKATQSNDEQVSFCVPSGNFGNVCAGHIAKQMGLPIR
                     RLIVATNENDVLDEFFKTGAYRPRNSEHTYVTSSPSMDISKASNFERFVFDLMDRDPQ
                     EINTLWAEVAAGKGFDLRFALDKVGGKYGFTSGKSTHADRLATIKQVYEQDQELIDPH
                     TADGVKVAREVREEGETVVCLETALAAKFDATIREAVGDVAIPRPAVLKGLETLPQRV
                     QTAPNSADAVKGIIEQTLA"
     gene            4912..5706
                     /locus_tag="ACFOV4_001179"
     CDS             4912..5706
                     /locus_tag="ACFOV4_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619198.1"
                     /translation="MTLPMQETRFSILLDELAAKQEAAIAPHLLADGTKVWVRKAGRH
                     NARWRYALLGMVARYLKLGVLKPVPSLGGEPAIATESKRLYELRSVGIAVPELLAVRK
                     NALMFGNLAGIPLDAQIRQEAEAGKADAWLAGLEAIARVHKKQQFLSQAFARNMMWDG
                     KNISFLDFEDDPSEVLTIAQCQARDWLCYIHSTALILKNGGLLEAAAEKWGGVLSEQP
                     AEIQRLIAATVKPILPIRRLEHPRWGRDALRLAASISLISLADIPP"
     gene            5894..6670
                     /locus_tag="ACFOV4_001180"
     CDS             5894..6670
                     /locus_tag="ACFOV4_001180"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004324 - ferredoxin-NADP+ reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP reductase"
                     /protein_id="HFC7619199.1"
                     /translation="MAAFNTQKVLSVHHWTDAYFTFTCTRDESLRFENGQFVMVGLMV
                     DGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDDVLISKKPTGTLVAG
                     DLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKEL
                     PEHEYLGDLVKEKLIYYPIVSREEFEHHGRLTDLMVSGKLFEDIGLPKINPQDDRAML
                     CGSPAMLKDTCKVLDDFGLTVSPKTGVRGDYLIERAFVDQ"
     gene            6746..6852
                     /locus_tag="ACFOV4_001181"
                     /pseudo
     CDS             6746..6852
                     /locus_tag="ACFOV4_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(7441..9912)
                     /locus_tag="ACFOV4_001182"
     CDS             complement(7441..9912)
                     /locus_tag="ACFOV4_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFC7619200.1"
                     /translation="MKKTCFHCGLDVPEHLHLTVRYENEDRETCCAGCQAVAQSIIDA
                     GLGSYYKQRTADAQKTELPPQEILDQIRLYDLPEVQSDFVETHGGTREAVLMLGGITC
                     AACVWLIEQQLLRTDGIVRIDLNYSTHRCRVVWDDGKIRLSDILLKIRQIGYTAAPYD
                     AQKIEAANQKERKQYIVRLAVAGLGMMQTMMFALPTYLYGGDIEPDFLQILHWGGFLM
                     VLPVVFYCAVPFYQGALRDLKNRRVGMDTPITVAIIMTFIAGVYSLATNAGQGMYFES
                     IAMLLFFLLGGRFMEHIARRKAGDAAERLVKLIPAFCHHMPDYPDTQETCEAAVVKLK
                     AGDIVLVKPGETIPVDGTVLEGSSAVNESMLTGESLPVAKMPSEKVTAGTLNTQSPLI
                     IRTDRTGGGTRLSHIVRLLDRALAQKPRTAELAEQYASSFIFGELLLAVPVFIGWTLY
                     ADAHTALWITVALLVITCPCALSLATPTALAASTGTLAREGILIGGKQAIETLAQTTD
                     IIFDKTGTLTQGKPAVRRISLLRGTDEAFVLAVAQALEQQSEHPLARAILNCRISDGS
                     VPDIAIKQRLNRIGEGVGAQLTVNGETQVWALGRASYVAEISGKEPQTEGGGSAVYLG
                     SQSGFQAVFYLTDPLKDSAAEAVRQLAGKNLTLHILSGDRETAVAETARALGVAHYRA
                     QAMPEDKLEYVKALQKEGKKVLMIGDGINDAPVLAQADVSAAAAGGTDIARDGADIVL
                     LNEDLRTVAHLLDQARRTRHIIRQNLIWAGAYNIIAVPLAVLGYVQPWIAALGMSFSS
                     LAVLGNALRLHKRGKMQSEKMPSEQ"
     gene            complement(9909..11087)
                     /gene="hflX"
                     /locus_tag="ACFOV4_001183"
     CDS             complement(9909..11087)
                     /gene="hflX"
                     /locus_tag="ACFOV4_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009347253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFC7619201.1"
                     /translation="MTGRTGRNGSTQAQPERVMLVGVMLDKDGTGSSADRLNGFQTAL
                     AEAVELVKAAGGDPVLVETAKRDRPHTALFVGTGKAAELSEAVAADGIDLVVFNHELT
                     PTQERNLEKILQCRVLDRVGLILAIFARRARTQEGRLQVELAQLSHLAGRLIRGYGHL
                     QSQRGGIGMKGPGETKLETDRRLIAHRINALKKQLSSLKKQRALRRKSRESGTIKTFA
                     LVGYTNVGKSSLFNRLTKSGIYAKDQLFATLDTTARRLYISPECSIILTDTVGFVSDL
                     PHKLISAFSATLEETAQADVLLHVVDAAAPNSGQQIEDVENVLQEIHAGDIPCIKVYN
                     KTDLLPSEEQNTGIWRDAAGKIAAVRISVAENTGIDALREAIAESCAAAPNTDETEMP
                     "
     gene            complement(11092..12372)
                     /locus_tag="ACFOV4_001184"
     CDS             complement(11092..12372)
                     /locus_tag="ACFOV4_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFC7619202.1"
                     /translation="MKSLVIWLLLLGSAAGVFYHTQNQSLLVGELVYPSAPQIRDGGD
                     ALHYLNRIRAQIGLHELAHAPVLENSARRHARYLTLNPEDGHGEHHPDNPHYTAQKLT
                     ERTRLAGYLYNGVHENISTEEEAAESSDSDIRTQQRQVNGLMSAIYHRLSLLDRHTDE
                     AGAAFVRENGKTVLVFNQGNGRFERACARRMQQPEAGRKYYRNACHNGAAVYADEVMP
                     ATELLYTAYPVGSGVLPYFYGERPDPMPGYEMTGNPVSIDFSEAAGKITMKSFKLYQG
                     KNEIRPVKVLTAGNDPNGRLTAYQFALFPIKPLEYGTLYTAVFDYVRNGRRAQAKWQF
                     KTRKPDYPYFEVNGGETLAVRKGEKYFIHWRGRWCLEACTRYTYRQRLGSRLSIGRHE
                     AGGIVFSVGGMTGSRITLAPEDSPERGVTLYLQD"
     gene            complement(12525..13250)
                     /locus_tag="ACFOV4_001185"
     CDS             complement(12525..13250)
                     /locus_tag="ACFOV4_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFC7619203.1"
                     /translation="METQNKPTVTDIDRPILVPPGGHKKVLLHSCCAPCSGEVMEAML
                     ASDIDYTIYFYNPNIHPHKEYMLRKEENVRFAEKFGIPFIDKDDDYENDRKEWFAKAK
                     GMEFEPERGIRCTMCFDMRFEKAAQYAHEHGFPVFTSSLGISRWKNMNQINDCGRRAA
                     APYDDVVYWDFNWRKGGGSARMIEISKRENFYQQEYCGCAYSLRDSNAHRKSQGRIPI
                     KLGVLYYGDESTQYEPAPIRVDK"
     gene            complement(13323..14000)
                     /gene="radC"
                     /locus_tag="ACFOV4_001186"
     CDS             complement(13323..14000)
                     /gene="radC"
                     /locus_tag="ACFOV4_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFC7619204.1"
                     /translation="MSIKQWPEGERPREKLLERGAAALSDAELLAILLRVGTRGMSAV
                     DLARYLLQEFGSLGRLMSAEVGKLSAYKGMGTASFTQFAVVREIGRRILAEELQEGIV
                     LSDPDTVADYLRFHLGQEKVEVSVALLLNRQNQLIAVRELSRGTVAENTIYIREIVKL
                     ALDEYADSLIIAHNHPGGSPEPSQEDIMFTRRLAQAMSLVDVSLLDHFIVTAQTVRSF
                     RQLGLMP"
     gene            14027..14149
                     /locus_tag="ACFOV4_001187"
     CDS             14027..14149
                     /locus_tag="ACFOV4_001187"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619205.1"
                     /translation="MPSETNVPTRQISEMPSEPDFRFRRHLYFKTVLRRFFQLD"
     gene            complement(14123..15472)
                     /gene="gshA"
                     /locus_tag="ACFOV4_001188"
     CDS             complement(14123..15472)
                     /gene="gshA"
                     /locus_tag="ACFOV4_001188"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HFC7619206.1"
                     /translation="MKLPVMSPEHSAQLQAFEAKILSNHAKIEAWFRTQWSVHRPPFY
                     GSVDIRNAGYKISSIDMNLFPGGFNNLNPNFIPLAAVAAQDAVQRACETAKSVLIIPE
                     NHTRNTFYLQNIYALGEILRSAGYEVRLGSLNPEVTEPTEFETALGDKILLEPLLRTR
                     DRVHLADGFSPCVVLLNNDLSAGIPDILKGISQTVLPPLHGGWTTRRKTNHFGAYNQV
                     TAEFAKLIGIDEWQINPYFEKIGGLDFQGREGEDALAEAVERVLAKIQAKYDESGITD
                     KPFVIVKADAGTYGMGVMSVKSADEVRGLNRKNRNKMAKVKEGLEVSEVIVQEGIYTY
                     ETLNGAVCEPVVYMMDRFVIGGFFRVHEGRGADENLNAGGMVFVPLSNSIPTGNGDNS
                     QEAPEACKRVFEQWDALGMPRSEKDCDVDNVHNRLYVYGVMARLSLLAASIELEETA"
     gene            15732..17141
                     /gene="leuC"
                     /locus_tag="ACFOV4_001189"
     CDS             15732..17141
                     /gene="leuC"
                     /locus_tag="ACFOV4_001189"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HFC7619207.1"
                     /translation="MTAQTLYDKLWNSHVVREEEDGTVLLYIDRHLVHEVTSPQAFEG
                     LKMAGRKLWRIDSVVSTADHNTPTGDWDKGIQDPISKLQVDTLDKNIKEFGALAYFPF
                     MDKGQGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCI
                     TAKKSKSMLIAVDGKLKAGVTAKDVALYIIGQIGTAGGTGYAIEFGGEAILSLSMEGR
                     MTLCNMAIEAGARSGMVAVDQTTIDYVKDKPFAPKGEAWDKAVEYWRTLVSDEGAVFD
                     KEYRFNAEDIEPQVTWGTSPEMVLDISSKVPNPAEETDPVKRSGMERALEYMGLEAGT
                     PLNEIPVDIVFIGSCTNSRIEDLREAAAIAKDRKKAANVQRVLIVPGSGLVKEQAEKE
                     GLDKIFIEAGFEWREPGCSMCLAMNADRLTPGQRCASTSNRNFEGRQGNGGRTHLVSP
                     AMAAAAAVTGRFTDIRMMA"
     gene            17238..17492
                     /locus_tag="ACFOV4_001190"
     CDS             17238..17492
                     /locus_tag="ACFOV4_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619208.1"
                     /translation="MNKLFITALSALALSACAGTWEGAKQDTARNLDKTQAAAERAAE
                     QTGNAVEKGWDKTKEAVKKGGNAVGRGISHLGGKIENATE"
     gene            17554..18195
                     /gene="leuD"
                     /locus_tag="ACFOV4_001191"
     CDS             17554..18195
                     /gene="leuD"
                     /locus_tag="ACFOV4_001191"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HFC7619209.1"
                     /translation="MKAFTKITAIVAPLDRSNVDTDAIIPKQFLKSIKRSGFGPNAFD
                     EWRYLDHGEPGMDNSKRPLNPDFSLNQPRYQGAQILLTRKNFGCGSSREHAPWALDDY
                     GFRAVIAPSFADIFFNNCYKNGLLPIVLTEEQVDRLFKEVEANEGYQLSIDLAEQTLT
                     TPGGETFTFDITEHRKHCLLNGLDEIGLTLQHADEIHAFEEKRRQSQPWLFNG"
     gene            18370..19640
                     /locus_tag="ACFOV4_001192"
                     /pseudo
     CDS             18370..19640
                     /locus_tag="ACFOV4_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            19656..20387
                     /locus_tag="ACFOV4_001193"
                     /pseudo
     CDS             19656..20387
                     /locus_tag="ACFOV4_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229413.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0090304 - nucleic acid metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NgoBV family restriction endonuclease"
     gene            20421..21491
                     /gene="leuB"
                     /locus_tag="ACFOV4_001194"
     CDS             20421..21491
                     /gene="leuB"
                     /locus_tag="ACFOV4_001194"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HFC7619210.1"
                     /translation="MTKHIAILRGDGIGPEIVAETVRVLDKLIAQGLDAGYEYAPLGG
                     EAYDEYGHPYPEFTQNLCRKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFA
                     NLRPAVLYPELANASTLKPEIVAGLDILIVRELTGDIYFGEPRGIRVLENGEREGYNT
                     MKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIGKEYPDIELS
                     HMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGLY
                     EPSHGSAPDIAGQNKANPLATILSLAMLLRYSLNDEARAQQVENAVQKVLQQGLRTSD
                     IYEEGTKLVSCSEMGDAILAAL"
     gene            21654..22217
                     /locus_tag="ACFOV4_001195"
     CDS             21654..22217
                     /locus_tag="ACFOV4_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HFC7619211.1"
                     /translation="MKKIIFAALAAAAVGTASAATYKVDEYHANARFAIDHFNTSTNV
                     GGFYGLTGSVEFDQAKRDGKIDITIPVANLQSGSQHFTDHLKSADIFDAAQYPDIRFV
                     STKFNFNGKKLVSVDGNLTMHGKTAPVKLKAEKFNCYQSPMAKTEVCGGDFSTTIDRT
                     KWGVDYLVNVGMTKSVRIDIQIEAAKQ"
BASE COUNT         5435 a         5867 c         5777 g         5267 t
ORIGIN      
        1 cggcatttcc aaagggcatt ttaagccgta tttgagagaa tgcggatggc gttttcagtg
       61 ttttcagcgt gataaaattc aaatttctat tttaaaacaa tcagcaaagc aggatttatt
      121 tcagttgtcc gagacaacgg gcggctgcac cgcctgcact ccccatactt tttcaatgca
      181 ctcgagcagg agtgagacgt ggggattatc ctcgtattct tccgcataaa tgaaattgag
      241 cggcatactg tggcggcacg attcgataat agccacgccc gcgccttctt ttgccgccgc
      301 ttcggctttg tttcccggca ccattgccac acctataccg cctgcaacca aatcgataat
      361 ggtttggggg tagtcgcaca agatctgttt tttgggtgag agccggttgc tgcgccaaaa
      421 ctggtgcagg tgcttcctac ttccggacac gcccgacatt tctatccata cgcattcttg
      481 caggctctgc ggaagggagc gggtcagatg gggatattgg ctttgcgggc aaatcagcgc
      541 gtaggtcagg ttttgcagga atacgctgcg gatgccgcgt tgggcggcgt tgccgagtat
      601 aaagccgccg tgcagggttt tgtgttggat gcgcgagagg atttcgccgc tcattccgta
      661 ttggatgtgc aggcgcgttt tgggggctgt ttgaccgata ttgtccgtca gcgcgacgag
      721 ttttgccgaa tcgatggggt ggataatgcc caaactggtc tcttccgaat aatcgcctgc
      781 cagcgttttg gcaaaatgct ccagcttgtg tttatattgc agcagggatt ccgcttcggg
      841 caacagtatt tcgcccgccc gcgtcaatac catgcctttc cccgtgcgcc tgaacagcgg
      901 cgtgccgaca tattcttcaa gggctttaat ttgggcagaa acggcaggct gggaaaggaa
      961 aagtcgtttg gcggcttggg taaggttgcc ctcgtgcgcg acggcgacaa atgattttaa
     1021 ttgtacggca tccatatatc cctccttgtg cggatgtttt ctatatttgt gcaatcgaaa
     1081 tcttttaggt ggattgttgc tgaaaattaa ctttttaatc aagtggtttg taaattgtat
     1141 cagttttccg gatgatggtt atcaaaaaaa aagattggtt ttattgcctg tttgggcttt
     1201 aaatggggtt acggcttccg aacgcagccc gtatcaaaaa gaaaagtcat gcgccccttt
     1261 tacgaggcgc gatatataag gaggaaggtt atggaaaaac ataatgggac ttatcgggat
     1321 ttgcaccgtc cggcttcgga atttgcgacg cgggacgaat atttggaaca tgaattgcag
     1381 attatgcaac caaaacgctg gcggcccaac ctgccctttc gcgattaccg cttcgagtgg
     1441 gaggatttga ttcctgcgat ggcgggaacg attggaaaag tggtgatggt gggggcggtg
     1501 gcggcggcgt ttgccgcacc tttggggctg cctgacagct ttgtactgga aaatgtgcgc
     1561 tatgagcttt taatcgccgc cgcgtttatc ttattggtat cgggcttttt tctgcccggc
     1621 gccaacctgc ccggtacgca cgggccgctg attccgatga ttcccatcgt tgtgtcggca
     1681 ggcgggcatc ctttggcgtt cggcatttcg attgcggttt taggtctgct gatggcttta
     1741 tttcgcggcg gcagtattat ggcgaagctg acaagcaacg gcgtatgcgg cggattatta
     1801 ctctatttgg gctttatcgg cacgacgggg caggtaaaaa aattgttttc gtgggcaggc
     1861 ggttttaata tgccctacat cgcttttacc gtcattattg taacgattgt gatgtacgct
     1921 ttgttggagc attggaaaaa acgctggtta gccgtgcctt tgggatgctt gattgccggt
     1981 gtggtggcat ttgcattggg tgcgccgttt gagtttcaca ccgcccccgg cctgcctcca
     2041 atgagtcctg cttattggtg gggtgaaaac agcggctggc atctggggtt gccgacggca
     2101 gaaagttttt tggttgtctt tccatttgcg gtattggctg ttgcaatgtg gtcgcccgat
     2161 tttttaggac atcaagtgtt ccaaaaaatc agctatccgg aaaaaaccga taaggtattg
     2221 atgaatatag acgacaccat gacaagttgt tctgtccgtc aagcagtggg ttctatttta
     2281 gggggtgcaa attttacctc ttcttgggga acttatatcg taccggcatc gattgccaaa
     2341 cgccccattc cgggcggtgc ggttttaacg gcggttttat gtattatcgc cgggttgtgg
     2401 ggctatccga tggacttggc gatttggcag ccggtattga gcgtagcctt ggtcgtaggc
     2461 gtatacttac cgcttttgga agcgggcatg gaaatgacgc gcaaaggcaa aaccacccaa
     2521 tccgccgcca tcgtggtgtt ctcttccgcc ttggtcaatc cggttttcgg ctgggcgttg
     2581 acgatgctgt tggataattt gggcttaatc ggctgcaaag agcgcagtgc gcaattaggt
     2641 ttcgccggac gcgtgttgat acccgcagta ggtttcttga tcttgtgtgt ggcgatgggt
     2701 gcggtcggga tgctgcccgg tatcccgccg tttttggaac acttcaaatc tttgggctag
     2761 gctgaaatcg gaaatgccgt ctgaaccgct ttcagacggc atttttgcaa acaggcaaaa
     2821 tgacggcggc gggatttttt attttcccga ttgaagtata atgttgccgg gcttcaaccg
     2881 gatattcaaa acggtttgtt ccaacactcg gaacggcgca taaaacgccg cctttcgcgt
     2941 tatcccgaac ggggcggcta atcagattct atcgccataa aaggcggggt ttcaaccgaa
     3001 aaggaattga gatgaataaa accttgtcta ttttgccggt ggcaatctta ctcggcggct
     3061 gcgccgccgg aggcggtaac acattcggca gcttagacgg tggcacaggc atgggcggca
     3121 gcatcgtcaa aatggcggtc gggagccaat gccgtgcgga attggacaaa cgcagcgaat
     3181 ggcgtttgac cgcgctggcg atgagtgctg aaaaacaggc ggaatgggaa aacaagattt
     3241 gcgcttgcgt cgcccaagaa gcacccgaaa ggatgaccgg caacgatgtg atgcagatgc
     3301 tggattcgtc cacgcgcaat caggcacttg ccgccctgac cgccaaaacg gtttccgcct
     3361 gcttcaaaca cctgtaccgc taaccttctt cagacggcat gaggcagatg ccgtctgaag
     3421 ccgttttcct gcaatttcga cagacgagaa aaatcatgaa atacatcagc acgcgcggcg
     3481 aaaccgcaca caaaccgttc agcgaagttt tattgatggg gcttgcaccc gacggcggcc
     3541 tgatgctgcc ggaacattat ccgcaaatcg ggcgcgaaac cttggacaaa tggcgcggtt
     3601 tagcttatcc cgaattggcg tttgaaatta tgcgcctgtt tgttacggat attccggagg
     3661 acgatttgcg cgacattctg aaccgtactt acacggaagc ggcgttcggt actaaggaaa
     3721 tcacccccgt ccgcacgctt tcagacggca tcaaaatcca agccttgtcc aacggcccga
     3781 cgctggcgtt caaagatatg gcaatgcagt ttttgggcaa tgcgtttgaa tatgttttaa
     3841 acaaagaagg caaaaaactc aatatcttgg gcgcaaccag cggcgatacg ggttcggctg
     3901 cggaatatgc cttgcgcggc aaaaaaggtg tgaatgtatt tatgctgtcg cccgatggca
     3961 aaatgagcgc gttccaacgc gcgcaaatgt acagcctgca agacgggaat atccacaata
     4021 tcgccgtgaa gggaatgttt gacgactgtc aggatattgt gaaggcggtg cagaacgatg
     4081 ccgtgttcaa ggaaaaatac catatcggta cggtcaactc gattaactgg ggacgcatcg
     4141 tcgcgcaagt ggtttattac tttgccggct atttcaaagc gacgcaaagc aatgacgagc
     4201 aagtcagctt ttgcgtgccg agcggcaact tcggcaacgt ttgcgcggga cacatcgcca
     4261 aacaaatggg cttgcccatc cgccgcctga ttgtcgcgac caatgaaaac gatgtgttgg
     4321 acgagttttt caaaaccggc gcataccgcc cgcgcaacag cgagcatact tatgttacct
     4381 ccagcccgtc gatggacatt tccaaagcgt ccaacttcga gcgtttcgtg ttcgacctga
     4441 tggatcgcga tcctcaggaa atcaatacgc tgtgggcgga agtggctgca ggcaaaggct
     4501 ttgacctgcg atttgccttg gacaaagtcg gtggcaaata cggctttact tccggcaagt
     4561 ccacccacgc cgaccgcctc gccaccatca aacaggttta cgagcaagac caagaactca
     4621 tcgacccgca cactgccgac ggcgtaaaag ttgcccgcga agtgcgcgaa gaaggtgaaa
     4681 cggtggtttg tttagaaact gcgttggcag cgaaattcga tgcaaccata cgcgaagccg
     4741 tcggcgatgt cgccattccg cgccccgccg tgctgaaagg tttggaaaca ttgccgcagc
     4801 gcgtgcaaac cgcgccgaat agtgcggatg cggtaaaagg catcatcgaa caaacccttg
     4861 cctgatgtcc cgtgtgggcg gcattccgtc cgaacttaag attgaaagaa aatgacctta
     4921 cctatgcagg aaacccgttt ttctatactg ctggacgaac tggcggcaaa acaggaggca
     4981 gccatcgctc cccacctgct tgccgacgga accaaggtat gggtacgcaa agcaggcagg
     5041 cacaatgcgc ggtggcgtta cgcgctgctc ggtatggttg cccgatattt gaaactgggg
     5101 gtgttgaagc cggttcccag cctcggcggc gagcctgcca ttgcaaccga atcaaaacgc
     5161 ctgtacgaat tgcgctcggt ggggatagcc gttcccgaat tgctcgccgt caggaaaaat
     5221 gcccttatgt tcggcaattt ggcaggcatc ccgctcgatg cgcaaatccg ccaagaagcc
     5281 gaagccggaa aggcggacgc ttggcttgcc ggtttggaag ccattgcacg cgtgcataaa
     5341 aaacagcagt tcctcagtca ggcgtttgca cgaaatatga tgtgggacgg aaaaaacatc
     5401 agctttctag attttgaaga cgacccttcc gaagtcctga ccatagcgca atgccaagcc
     5461 cgcgattggc tctgctacat ccattcgacc gcgctgatat tgaaaaacgg cggactgctg
     5521 gaagcggctg cggaaaaatg gggcggcgta ctgtctgagc agcctgccga aatacaaagg
     5581 ctgattgccg ccaccgtcaa accgatcctc ccgatacgca ggctggaaca cccccgctgg
     5641 ggacgggacg cgctcaggct ggcagcctcg atttccctga tttcccttgc cgatataccg
     5701 ccataagccg ccgcccgccc cgcgatgccg tctgaagccc ttcagacggc atataaccaa
     5761 cgcgcatcaa gcattgtcgc aaccatccgt ttcgtttaga attttgactt tatcccgaat
     5821 cgggcagaca ttttcactct gccgcacatc ccgaacaagc actatccatt tcttttactg
     5881 acaggaaacc caaatggcag cattcaatac ccaaaaagta ttgtccgtac accactggac
     5941 agacgcatat tttaccttta cctgcacccg cgacgaatcg ttgcgctttg aaaacggaca
     6001 gttcgttatg gtcggattga tggtggacgg caagccgctg atgcgcgcat acagcgtcgc
     6061 ctccgccaac tgggaagaac acctcgaatt tttcagcatt aaagtccaag acggtccgct
     6121 gaccagccgc ctgcaacacc tcaaagtcgg cgacgacgtg ttaatcagca aaaaaccgac
     6181 cggaaccctg gttgccggcg acctgaatcc gggcaaacac ctttacttgt tgagcaccgg
     6241 taccggcatc gctcctttct tgagcatcac caaagacccc gaaatttacg agcaatttga
     6301 aaaaatcatc ctcgtacacg gcgtgcgcta caaaaaagat ttggcgtact acgaccgctt
     6361 taccaaagaa ttgcccgaac acgaatacct cggtgacttg gttaaagaaa aactgattta
     6421 ctacccgatt gtttcgcgcg aagaattcga acaccacggt cgcctaaccg acctgatggt
     6481 gagcggcaaa ctgtttgaag acatcggcct gcccaaaatc aacccgcaag acgaccgcgc
     6541 catgctgtgc ggcagccccg cgatgctgaa agatacctgc aaagttttgg acgatttcgg
     6601 actgaccgtc tctccgaaaa caggcgtacg cggcgattac ctgattgagc gtgcgtttgt
     6661 agatcaataa gctgtttgaa aatcccgtct gaacggcacc agcaatcaaa aaccccgaat
     6721 cctgccaatc aggattcggg gtttttatag tgaattaaat ttaaatcagg acaaggcggc
     6781 gagccgcaga cagtacaaat agtacggcaa ggcgagccaa cactgtaccg gtttaaattt
     6841 aattcactat atagtgggta aaaattagaa atgcacattt ccgtcattcc aacacaggtg
     6901 ggaatccgga cttacctgtt tcattatcgt ttgaaaataa aagagaaacc aaacatatag
     6961 attcccgctt gcgcgggaat gacgacggtg ttttgccgta gccaaagcag aaaaacatcc
     7021 ctattgtcat ttcatcatga tatgacaata ggatgttaaa aattaattat cattatatga
     7081 ttgatatata agaaaaactg tcccaataag aaatgttatg cagaaaataa aatgaaaagg
     7141 atggttttca ttgaaaatgg ttgttctgcc accgtcatac acagagccag tatttggaaa
     7201 aaaatgatcc atattgacat cattattcca tttgtcgcat aaatccactt tttaattttt
     7261 tccacattaa tataatctct tatttaataa aatcaaaata aaaatcaaat gcctaacaat
     7321 tcgatctcaa attttgaacg ccaacgtgtt tgagcggtaa caatacatac tttaagtttg
     7381 caattcttca tcgtcttatt tttgttttca tcaactatac gtctaaagca acgccgtccg
     7441 tcattgttcg gacggcattt tttcagactg cattttcccc cgtttgtgaa ggcgcagggc
     7501 gttgcccaaa accgccagcg aactgaagct catacccagt gcggctatcc acggttggac
     7561 atagcccaaa acggcaagcg gtacggcaat gatattgtac gcgcccgccc atatcaggtt
     7621 ttgccggata atatggcggg tgcgccgcgc ctgatcgagc aggtgggcga cggtacgcaa
     7681 atcttcgttc aataacacaa tgtccgcgcc gtccctcgca atatccgtcc cgcccgctgc
     7741 ggcggcggat acgtctgcct gcgccaaaac gggcgcgtcg ttgatgccgt cgcctatcat
     7801 cagcactttt ttcccttctt tttgcaaggc tttgacgtat tccagtttgt cctcgggcat
     7861 ggcttgggcg cggtagtgcg cgacacccag ggcgcgtgcg gtttcggcaa cggcggtttc
     7921 gcggtcgccg ctgaggatgt gcagggtcag gtttttgcct gccaactgcc gcaccgcctc
     7981 cgccgcgctg tctttcaagg ggtcggtcag gtagaacacg gcttggaaac cgctttgact
     8041 gccgaggtaa accgcgctgc cgccgccttc tgtttgcggt tctttacctg aaatttcggc
     8101 gacataggat gccctgccca atgcccaaac ctgtgtttcg ccgttgacgg tcagttgcgc
     8161 gcccacgcct tcgccgatgc ggttgaggcg ttgtttaata gcgatgtcgg ggacgctgcc
     8221 gtctgaaatg cggcagttga ggatggcgcg ggcaagggga tgttcggact gttgttctaa
     8281 agcctgcgcc accgcgagaa caaaggcttc gtctgtgcct ctcaacaatg agatacggcg
     8341 gacggcgggt ttgccttggg tcagcgtgcc ggttttgtcg aagatgatgt cggtggtttg
     8401 ggcgagggtt tcgattgcct gctttccgcc gattaaaata ccttcgcgcg ccagcgtacc
     8461 ggtagaagct gccagcgcgg tcggcgtggc aagcgataag gcgcaggggc aggtaatgac
     8521 cagcagggcg acggtaatcc acaatgcggt gtgcgcgtcg gcgtacagcg tccagccgat
     8581 gaagacgggg acggcaagca ggagttcgcc gaatatgaaa gacgaggcgt attgttccgc
     8641 caactcggca gtgcgcggtt tttgcgctaa ggcgcggtcg agcaggcgga cgatgtgcga
     8701 cagtcgcgtg ccaccgccgg tgcggtcggt gcgtataatc agggggcttt gcgtgttgag
     8761 tgtgccggcg gttacttttt cagacggcat tttggcgacg ggcaggctct cgccggtcag
     8821 catagattcg ttgacggcac tgcttccttc cagcaccgtg ccgtcaacgg ggatggtttc
     8881 gcccggtttg accagcacga tatcgcccgc cttcaatttg acgacagctg cctcgcaggt
     8941 ttcctgcgta tcggggtaat cgggcatatg atggcaaaac gcaggaatca gcttcaccag
     9001 cctctcggcg gcatcgcctg ccttacggcg ggcaatgtgt tccataaagc gtccgcccag
     9061 caggaaaaac agcagcatcg cgatggattc gaaatacatc ccctgccccg catttgtcgc
     9121 aaggctgtaa acgccggcga taaaggtcat gatgatggcg acggtaatcg gcgtatccat
     9181 gccgacgcgg cggtttttca agtcgcgcag cgcgccttga taaaacggga cggcgcaata
     9241 gaatacgacg ggcagcacca ttaaaaagcc gccccaatgg aggatttgca ggaaatcggg
     9301 ttcgatgtcg ccgccgtaaa ggtaggtcgg cagcgcgaac atcatcgtct gcatcatccc
     9361 cagcccggca acggcgaggc ggacgatgta ttgtttgcgt tctttttggt tggcggcttc
     9421 gattttttgc gcgtcatagg gtgcggcggt gtagcctatc tgcctgattt tcaacagaat
     9481 gtcggaaagg cggattttgc cgtcgtccca gacgacgcgg cagcggtgcg tgctgtaatt
     9541 gaggtcgatg cggacgatgc cgtctgtacg caaaagctgc tgttcgatca gccagacgca
     9601 ggcggcgcag gtgatgccgc cgagcattaa aaccgcctcg cgcgtgccgc cgtgggtttc
     9661 cacaaagtcg gactggactt cgggcaggtc gtacaggcgg atttggtcga ggatttcttg
     9721 gggcggcagc tcggtttttt gcgcgtcggc ggtgcgttgt ttgtaataac tgcccaagcc
     9781 cgcgtcaata atgctttgtg cgaccgcctg acagccggcg cagcaggttt cgcggtcttc
     9841 gttttcgtaa cggacagtca ggtggaggtg ttcgggaaca tccagaccgc agtggaaaca
     9901 ggtttttttc atggcatttc ggtttcgtct gtgtttggtg cggcggcaca agactcggca
     9961 atggcttcgc gcagtgcgtc tataccggta ttttcagcaa cggaaatgcg gacggcggca
    10021 atttttcccg cagcgtcgcg ccatatgccc gtgttttgtt cttcagacgg cagcaggtcg
    10081 gttttgttgt acaccttgat gcacggaata tcgccggcat ggatttcttg cagtacgttt
    10141 tccacgtctt caatctgctg tccgctgttc ggagcggcgg catcgacgac gtgcagcagc
    10201 acatcggctt gcgcggtttc ttccagcgtg gcggaaaagg cggaaatcag tttgtgcggc
    10261 agatcgctga cgaatccgac ggtatcggtc aggataatgc tgcattcggg actgatgtac
    10321 agccgccgcg ccgtcgtgtc gagtgtggcg aaaagctggt ctttcgcata tatgcccgac
    10381 ttggtcagcc ggttgaacag gctggatttg ccgacattgg tatagccgac cagcgcaaac
    10441 gttttgattg tgcccgattc gcgggacttg cggcgcaggg cgcgctgttt tttgaggctg
    10501 gaaagctgtt ttttcaaggc gttgattcga tgggcgatca atcggcggtc ggtttccagt
    10561 ttggtttcgc ccggcccttt catgccgatg ccgccgcgct ggctttgcag gtgtccgtaa
    10621 ccgcgtatca agcgtcccgc caaatggctc aactgcgcca attcgacttg cagcctgcct
    10681 tcctgcgtgc gggcacggcg ggcaaaaatc gccaaaatca gccctaccct gtccaacacg
    10741 cggcattgga ggattttttc caaattgcgc tcctgcgtgg gcgtgagttc gtggttgaat
    10801 acgaccaaat cgatgccgtc tgcggcaact gcttctgaca gctccgccgc cttgcccgta
    10861 ccgacaaaca gcgcggtgtg cgggcggtcg cgtttggcgg tttccacaag gacgggatcg
    10921 ccgcctgccg ctttgaccag ctcgacggct tccgccaatg ccgtctgaaa accgttcaga
    10981 cggtcggcac tgctgcccgt accatctttg tccaacatta cgcccaccag catgacgcgt
    11041 tcgggttgcg cttgggtact gccgttgcgg cctgttctgc ctgtcatgta ttcaatcctg
    11101 taaataaagg gtaacgccgc gttccgggct gtcttccggt gcaagcgtga tgcggctgcc
    11161 cgtcattccg ccaacgctga agacgatgcc gcccgcctcg tgccgtccta tggacaggcg
    11221 gctgccgagc cgctgccggt aggtataacg ggtacacgct tccagacacc agcgtccgcg
    11281 ccagtgaatg aaatattttt cgccttttct aaccgcaagc gtctcgccgc cgtttacctc
    11341 aaaataaggg taatcgggtt ttcgggtttt aaactgccat ttcgcctgcg cgcgccgtcc
    11401 gttgcggaca tagtcgaata ccgccgtata aagcgtaccg tactccaaag gcttgatcgg
    11461 gaaaagcgcg aattggtacg ccgtcagcct gccgttgggg tcgttgccgg cggttaaaac
    11521 tttgacggga cggatttcgt ttttaccctg atacagcttg aaacttttca tcgtaatttt
    11581 gcctgccgcc tcagaaaaat caatgctgac aggattgccc gtcatttcat atcccggcat
    11641 ggggtcggga cgctccccgt aaaaataagg cagcacgccg ctgccgactg gataggcggt
    11701 ataaagcaat tccgttgcgg gcatgacttc gtcggcataa acggctgcac cgttatggca
    11761 ggcattacgg taatatttcc gtcctgcttc cggctgctgc attctccggg cacaggcgcg
    11821 ctcaaacctg ccgttacctt ggttgaatac gagaacggtt ttaccgtttt cgcgcacaaa
    11881 tgccgctcct gcctcatccg tatggcggtc aagcagggaa aggcggtggt agattgcgct
    11941 catcaatccg ttaacctggc gttgctgcgt gcggatatcg ctgtcggacg attcggcggc
    12001 ttcctcttcc gtgctgatgt tttcatgtac gccattgtaa agataaccgg caaggcgtgt
    12061 gcgttcggtc agcttttgtg cggtgtagtg cggattgtcg ggatggtgtt cgccgtgtcc
    12121 gtcttcggga ttaagcgtga gataacgtgc gtgcctgcgg gcggagtttt ccaaaaccgg
    12181 cgcgtgtgcc agctcgtgca aaccgatttg tgcgcggatg cggttgaggt agtgcagcgc
    12241 gtcgccgccg tccctgattt gcggtgcaga cggatagaca agttctccca caagcaggga
    12301 ttggttttgg gtatggtaga aaacgcctgc cgccgaaccc aacagaagca gccagataac
    12361 aagggatttc atgatgtcgc cctctcgccc cggcaacggg atatttcatg aaaacggcaa
    12421 acttgaaaat cacgtttccg cttgccgatt gccaaaccgg caaacctttc cccgtgccga
    12481 tgccgaaccc gatgccgtct gaaccttcag acggcatcag gtgtttattt gtccacccgg
    12541 atgggtgcag gttcgtattg tgtcgattcg tcgccgtaat acagcacgcc gagtttgatg
    12601 gggatgcgtc cctgcgattt gcggtgggca ttggaatcgc gcaaggaata ggcgcagccg
    12661 caatattcct gctggtagaa gttttcacgt ttgctgattt caatcatacg cgcgctgccg
    12721 ccgcctttgc gccagttgaa atcccaatac accacatcat cgtaaggcgc ggcggcgcgg
    12781 cggccgcagt cgttaatctg gttcatgttt ttccaacggg aaatgcccag cgagctggtg
    12841 aagacgggaa acccgtgttc atgcgcatat tgcgccgcct tttcgaaacg catatcgaaa
    12901 cacatggtgc agcggatgcc gcgctcaggt tcgaattcca tacctttggc tttggcaaac
    12961 cattctttgc ggtcgttttc gtaatcgtcg tctttgtcga tgaaggggat gccgaacttt
    13021 tccgcaaagc gtacgttttc ctcttttcgg agcatatatt ctttgtgcgg atggatattg
    13081 ggattgtaaa aataaatggt gtaatcaatg tcgctggcca gcatggcttc catcacttcg
    13141 ccgctgcacg gggcgcagca ggaatgcagc aagacttttt tatgtccgcc gggcgggacg
    13201 agtatggggc ggtcaatgtc ggtaacggta ggtttgtttt gtgtttccat taacttaaca
    13261 atatctgtcg aatacggttg aagcggctat tttatcagag ccgccgcatg taaaacaggg
    13321 tgtcagggca tcagcccgag ctgtctgaac gaacggacgg tttgcgccgt tacgataaaa
    13381 tggtcgagca gcgacacatc gaccagcgac attgcctgtg ccagccgcct tgtgaacatg
    13441 atgtcttcct gcgaaggttc gggcgagccg cccggatggt tgtgcgcgat aatcaggctg
    13501 tcggcatatt cgtccaatgc cagtttgacg atttctcgga tgtaaatcgt gttttccgca
    13561 accgtaccgc gcgacagctc tctgaccgca atcagttggt tttggcggtt cagcagcagt
    13621 gcgacgctga cttcgacttt ttcctgtccc aaatgaaagc gcaggtaatc ggcaaccgta
    13681 tcggggtcgg acaggacgat gccctcctgc aattcttccg ccaatatccg ccgcccgatt
    13741 tccctgacca cggcgaactg tgtgaaactt gccgtcccca tccctttgta tgccgacagt
    13801 ttgccgacct ccgcgctcat cagcctcccc aaactgccga actcctgcag caaataacgc
    13861 gccaaatcga ccgcactcat tccgcgcgtg ccgacgcgca gcaggattgc caaaagttcg
    13921 gcatcactca aagccgccgc cccgcgttcc aacagctttt ccctgggcct ttcgccttcc
    13981 ggccattgct tgatgctcat gttttccctt ttttaaatag tctgagatgc cgtctgaaac
    14041 aaatgttccc acacgccaaa tatccgaaat gccgtctgaa ccggatttcc gcttcagacg
    14101 gcatctgtat ttcaaaacag tcttacgccg tttcttccaa ctcgattgaa gccgccagaa
    14161 gcgacaggcg tgccatcacg ccgtacacat agaggcggtt gtggacatta tcgacatcgc
    14221 agtctttttc agaacgcggc atacccagcg catcccattg ctcaaatacg cgcttgcagg
    14281 cttcgggtgc ttcttgggaa ttatcgccat tgccggtagg aatgctattg gacagcggca
    14341 caaacaccat accgccggcg ttgaggtttt cgtccgcacc gcgcccttcg tgtacgcgga
    14401 aaaagccgcc gatgacgaag cggtccatca tatacacgac gggttcgcac accgcgccgt
    14461 ttaaggtttc ataagtataa atcccttctt ggacaatcac ttcgctgact tccaagcctt
    14521 ctttgacttt cgccatttta ttgcggtttt tacggttcaa tccgcgcact tcgtcggcgg
    14581 atttgacgct catcacgccc atgccgtaag tgccggcatc ggctttgacg atgacgaaag
    14641 gtttgtcggt aatgcccgat tcgtcgtatt tggcttgaat tttcgccagc acacgttcta
    14701 ccgcttccgc caacgcgtct tcgccttcac gcccttggaa gtccaaaccg ccgatttttt
    14761 caaaataagg gttaatttgc cattcgtcga tgccgattaa cttggcaaat tcggcggtaa
    14821 cttggttgta cgcgccgaaa tgatttgttt tgcggcgcgt cgtccaaccg ccgtgcaacg
    14881 gcggcaaaac ggtttggctg atgcctttga ggatgtcggg aatgccggca gacaaatcgt
    14941 tgttcaacaa aaccacgcaa ggcgaaaagc cgtctgcaag atggacgcgg tcgcgggtac
    15001 gcaataaagg ttccaacagg attttgtcgc ccaatgcagt ttcaaattcg gtcggttcgg
    15061 ttacttccgg attcaggctg cccaagcgca cttcataccc tgccgaacgc aaaatctcgc
    15121 cgagggcgta aatgttttgc aggtaaaacg tattgcgcgt gtggttttcg ggaataatca
    15181 atacggattt cgccgtttcg caggcgcgtt gcaccgcatc ttgcgcggca accgccgcca
    15241 gcgggataaa gttgggattc agattattga agccgccggg gaacaaattc atatcgatag
    15301 acgaaatttt gtaaccggca ttgcgtatat cgaccgaacc gtaaaacggc gggcggtgta
    15361 cgctccactg cgtgcggaac cacgcctcga ttttggcgtg attggacagg atttttgcct
    15421 caaacgcctg aagttgcgcc gaatgttcgg gcgacatcac cggtaatttc atctttcgtc
    15481 tgcctctgtg tgttttttga caagatgcag atgataatgc ctttgaaaga atgacgacaa
    15541 gtattctttc gtatcgaatc atgctttaga tataactgtt tactgaaatg gacaatacgt
    15601 ctaatttttt cgttaaaatt gtttgcaaaa taacaccggc tcaaaaatta gacaaaattt
    15661 gttgcgcggt ataaagaata cgtctaaaat ccgcccaatc cgcattacca tttatccaaa
    15721 agaacaacat catgacagca caaaccctct acgacaaact ttggaacagc cacgtcgtcc
    15781 gcgaagaaga agacggcacc gtcctgctct acatcgaccg ccatttggtg cacgaagtta
    15841 ccagccctca ggcatttgaa ggcttgaaaa tggcggggcg caagctgtgg cgcatcgaca
    15901 gcgtcgtctc caccgccgac cacaacaccc cgaccggcga ttgggacaaa ggcatccaag
    15961 acccgatttc caagctgcaa gtcgatactt tggacaaaaa cattaaagag tttggcgcac
    16021 tcgcctattt tccgtttatg gacaaaggtc agggcatcgt acacgttatg ggccccgaac
    16081 aaggcgcgac cctgcccggt atgaccgtcg tctgcggcga ctcgcacact tccacccacg
    16141 gtgcattcgg tgcgttggca cacggcatcg gcacttccga agtcgagcac accatggcaa
    16201 cccagtgtat taccgcgaaa aaatccaaat ccatgctgat tgccgttgac ggcaaattaa
    16261 aagcgggcgt taccgccaaa gacgtggcac tttacatcat cgggcaaatc ggcacggcag
    16321 gcggtacagg ctacgccatc gagtttggcg gcgaagccat cctcagcctt tctatggaag
    16381 gccgcatgac tttatgcaat atggcgatcg aagccggtgc gcgctcaggc atggttgccg
    16441 tcgaccaaac caccatcgac tatgtaaaag ataaaccctt cgcacctaaa ggcgaagcat
    16501 gggacaaagc cgtcgagtac tggcgcacgc tggtgtctga cgaaggtgcg gtattcgaca
    16561 aagaataccg tttcaacgcc gaagacatcg aaccgcaagt cacttggggt acctcgcctg
    16621 aaatggtttt agacatcagc agcaaagtgc cgaatcctgc cgaagaaacc gatccggtca
    16681 aacgcagcgg tatggaacgc gcccttgaat acatgggctt ggaagccggt acgccattaa
    16741 acgaaatccc cgtcgacatc gtattcatcg gctcttgcac caacagccgc atcgaagact
    16801 tgcgcgaagc cgccgccatc gccaaagacc gcaaaaaagc cgccaacgta cagcgcgtgt
    16861 taatcgtccc cggctccggt ttggttaaag aacaagccga aaaagaaggc ttggacaaaa
    16921 ttttcatcga agccggtttt gaatggcgcg aaccgggctg ttcgatgtgt ctcgccatga
    16981 acgccgaccg cctgaccccg gggcaacgct gcgcctccac ctccaaccgt aactttgaag
    17041 gccgtcaagg caacggcgga cgtacccacc tcgtcagccc cgctatggca gcagcagccg
    17101 cagtgaccgg ccgctttacc gacatccgca tgatggcgta agtattttca ggcggtcttt
    17161 aagaatttga cgcggccgtc tgaaatatgt cccgtaaggc agaaacacct ttaatattca
    17221 aaccaaggag tttaaccatg aacaaacttt tcattaccgc cctgtccgcc ctcgccttgt
    17281 ccgcctgcgc cggcacttgg gagggcgcga aacaagacac cgcccgcaac cttgacaaaa
    17341 cacaggccgc cgccgaacgc gccgccgaac aaacaggcaa cgccgtcgaa aaaggctggg
    17401 acaaaaccaa agaagccgtc aaaaaaggcg gcaatgccgt cggacgcggc atttcccatc
    17461 tcggcggaaa aatcgaaaac gccaccgaat aaccgattcg cgatgccgtc tgaaaccgct
    17521 tcagacggca tcgtcagcac aagacgcaaa cccatgaaag cctttaccaa aattaccgcc
    17581 atcgtcgccc cgctcgaccg cagcaacgtc gataccgacg ccatcatccc caaacaattt
    17641 ttaaaatcca tcaaacgcag cggcttcggc cccaatgcct ttgacgaatg gcgttacctc
    17701 gaccacggcg aaccaggcat ggacaacagc aaacgcccgt tgaaccctga tttctcgctg
    17761 aaccagccgc gttaccaagg cgcgcaaatc ctgttgacgc gtaaaaactt cggttgcggc
    17821 tcttcacgcg aacacgcccc ttgggcattg gacgactacg gcttccgcgc cgtcatcgcc
    17881 cccagcttcg ccgacatctt cttcaacaac tgctacaaaa acggcctttt acctatcgtg
    17941 ttgaccgaag aacaggttga ccggcttttc aaagaagttg aagccaacga aggctatcag
    18001 ctctccatcg accttgccga acaaaccctg accacccctg gcggcgaaac attcacattc
    18061 gacattaccg aacaccgcaa acactgcctc ttaaacggct tggacgaaat cggactgacc
    18121 ctgcaacatg ccgatgaaat tcacgccttt gaagaaaaac gccgccaaag ccagccttgg
    18181 ctgtttaacg gttaaaacct atgccgtctg aaggccgttc agacggcatt cctgataaca
    18241 tataattgtt gcggctaatg taaacagagg ggcgataaat tgctttcatc ttttaagcgg
    18301 gcttagcgac actctaaatt aatgcaataa tgcaactctc catttcaaat aaatttttag
    18361 atttttaata tgcaacaaat taaatttatt gacttatttt ccggaatgag tggcatcagg
    18421 aaaggattcg aacaagcctg tcggaaacag tcggttgctt gcgaatgtgt ttttacttca
    18481 gaaatcaaac cggcagcttt ggaagtattg aagcaaaact accctgatga agtgccgtat
    18541 ggagatataa cgaaaattga aacaggggat attcccgatt ttgacatcct gttggcaggc
    18601 ttcccttgtc aggctttttc tttcgccgga aaaagattag gctttgaaga tacacgggga
    18661 acgcttttct ttgatgtggc aaggatttta aaggcaaaaa aaccaaaagg ttttattttg
    18721 gaaaatgtgg aaggattggt gacacacgat agaaaagatt cgacacaaaa aatagggcgc
    18781 accctgaccg ttattttgga aaccttggaa gcattgggct actatgtttc ttggaaagtt
    18841 ttaaatgcaa aagatttcgg cattccccaa aacaggaagc gcatttatct gacaggcagt
    18901 ttgaaatcca aacccgactt atctttcgaa acaagcccaa gtccgaaatt aaaaaatatt
    18961 ttggaatcgg gactgcctac cgaaagcagc cctttcatca aaaaattgct aaaaaaattt
    19021 cccccgtccg aactgtacgg aaaatcagta aaagacaaac ggggagggaa aaacaatatt
    19081 cacagttggg atattgaatt aaaaggcgca gtaaccgaag aagagaagca attgttaaat
    19141 atccttctaa aagaacggag gaaaaaaaat gggcttcaga aatcggcata gattggatgg
    19201 atgggatgcc tttgacaaaa gcgcaaattt caactttcta taaacacccc aatctccaaa
    19261 atattttgga cagcctgaca gataaaggct atttggtttt agagcatccg aaacaaaaaa
    19321 ttggcgggca aagaatcaaa gatgaatccc tgcccaaagg ctacaatatt gtttcaggta
    19381 aaaaatcttt tgaaatcaat aaaatattag atccaaacga tgttgcgcca accttggttg
    19441 caatggatat ggagcacctt ttcgtcgttg acaacggcgg tttgcgtaca cttaccggaa
    19501 aagaagggtt gcgcttattc ggctatccgg acgattattc gtttgatatt cccaaaaaag
    19561 acagatgcga tttattgggt aataccgttg tcgtccctgt gattaaggcg gtatctgaaa
    19621 gacttctgca tactttataa accgacaggg ataaaatgat aaaacttact gcacaacaaa
    19681 tatttgataa gttgctggat gaagaaaaaa tcttatcggc caatggtcaa attagatttt
    19741 tcttaggcga tgtggatatt atcgtcaaac aaaaagatgt tgtcggcaac atcattcagg
    19801 aatggctcgg cggatgattg agaaaaaggg aaattgaatt tgatgtttca accaataccc
    19861 aaatgcctcc cgatttcttt ttaaataaaa aagaccgcag cagagaattg ttggaagtaa
    19921 aggcgttcaa ccgaaatacc ggcccgggtt ttgatattgc agattttaaa atgtattctg
    19981 atgaaatcat tcataagccc tatatgctgg atgtagacta tttaatattc ggttacgata
    20041 tggacgacaa cggcaatgta accatcaagg atttatggct taaaaaagta tggcaaatta
    20101 cgagaagcat ggatgggtgg gcaattaatc ttcaagtcaa aaaaggcgtg gtgcataaaa
    20161 tccgcccggg tgtttggtac agcataaata aaaagaatat gcctatgttt gaatgcttgg
    20221 aagattttgt ttccgcaatt gaagaaaccg tttatcaaaa cccggcaaca cggcataacg
    20281 catccttatg gaaaaagaaa tttgaggaag cctataaaaa acactacaac cgatcgattt
    20341 ccatacctcg ttggcacgaa attgcacaca aatacaaaaa gaaataaccc ttcaaccatc
    20401 aacccataag gaaacttgaa atgaccaaac atatcgccat cctccgaggt gacggcatcg
    20461 gtcccgaaat cgtcgccgaa accgtccgcg tactcgacaa actcatcgcc caaggtttgg
    20521 atgccggcta cgaatacgcc ccattgggcg gcgaagccta tgacgaatac ggtcatcctt
    20581 atcccgaatt tacgcaaaac ctctgccgca aagccgatgc cgtcctgctt ggtgcagtcg
    20641 gttctcctca atacgacaac ctcgaccgtc cgttgcgccc tgagcgcggc ctgttggcaa
    20701 tccgtaagga tttgaacctg tttgccaatt tgcgtcctgc tgttttatat cccgaattag
    20761 ccaacgcctc cacgctgaag cctgaaatcg ttgccggttt ggatattttg attgtgcgcg
    20821 aactcaccgg cgacatctat ttcggcgaac cgcgcggcat ccgcgttctg gaaaacggcg
    20881 aacgcgaagg ctacaacacc atgaaataca gcgaaagcga aatccgccgt attgcccatg
    20941 ttgccttcca atccgcccaa aaacgcagca aaaaagtctg ttccgtaggc aaagccaacg
    21001 ttttggaaac caccgaattg tggcgcgaaa tctttgaaga aatcggcaaa gagtaccctg
    21061 atatcgagct ttcccatatg tacgtcgaca acgccgccat gcagctcgtg cgtgcgccca
    21121 aacaattcga cgtcattgcc accggcaaca tcttcggcga cattctctcc gacgaagcct
    21181 ccatgctgac cggctccatc ggtatgctgc cttccgcctc gctggacgaa aacggcaaag
    21241 gcctgtacga accgtctcac ggctccgccc ccgacatcgc cggacaaaac aaagccaacc
    21301 cgctggccac catcctctcg ctcgcaatgt tgctgcgtta cagcctgaac gacgaagcgc
    21361 gcgcgcaaca agttgaaaac gccgtccaaa aagtgctgca acaaggcttg cgtaccagcg
    21421 acatttacga agaaggcaca aaactcgttt cctgctccga aatgggcgat gcgatactcg
    21481 ccgccttgta aaaaaacaaa gcgcggatca caccgcgctt tttcatccgc ccttttccgc
    21541 ccgccccgtt cgtcaaccgc ctgcaaaccc accgtttacc ggcaggaaat gccataaatc
    21601 cctgcctatg ttaggataaa cacctttatc ggcccacaca aaggattatc atcatgaaaa
    21661 aaatcatctt cgccgcactc gcagcggcag ccgttggcac tgcctccgcc gccacctaca
    21721 aagtggacga atatcacgcc aacgcccgtt tcgccatcga ccatttcaac accagcacca
    21781 acgtcggcgg tttttacggt ctgaccggtt ccgtcgagtt cgaccaagca aaacgcgacg
    21841 gtaaaatcga catcaccatc cccgttgcca acctgcaaag cggttcgcaa cactttaccg
    21901 accacctgaa atcagccgac atcttcgatg ccgcccaata tccggacatc cgctttgttt
    21961 ccaccaaatt caacttcaac ggcaaaaaac tggtttccgt tgacggcaac ctgaccatgc
    22021 acggcaaaac cgcccccgtc aaactcaaag ccgaaaaatt caactgctac caaagcccga
    22081 tggcgaaaac cgaagtttgc ggcggcgact tcagcaccac catcgaccgc accaaatggg
    22141 gcgtggacta cctcgttaac gttggtatga ccaaaagcgt ccgcatcgac atccaaatcg
    22201 aggcagccaa acaataaatc ttgatgcgaa tcagcacaaa tgccgtcttc atcaaaccgc
    22261 cccgccaacg gtaagccgat atggcggagc acaatccgcc gaaagatatt tcagcggcag
    22321 gcagggcttg ccggaaagtc cggaaa
//
LOCUS       DAXISH010000032        21894 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.032, whole genome shotgun sequence.
ACCESSION   DAXISH010000032 DAXISH010000000
VERSION     DAXISH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 21894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21894
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.032"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..1167)
                     /gene="hemW"
                     /locus_tag="ACFOV4_001196"
     CDS             complement(<1..1167)
                     /gene="hemW"
                     /locus_tag="ACFOV4_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFC7619212.1"
                     /translation="MHTISFPNRTRLTALPPLSLYIHIPWCIKKCPYCDFNSHSLKNG
                     LPEAAYIDALLTDLQLELPNIWGRPVETIFFGGGTPSLFQAESIDRLLSGVRSLLRLQ
                     PEAEITLEANPGTFEIEKFQGFKDAGITRLSIGVQSFNDDMLSRLGRVHNGKEALTAI
                     DTALKLFDKVNIDLMYALPNQTVQTALDDVQTAIATGATHISAYHLTMEPNTPFGHTP
                     PKGLPQDEAALDIEDAVHGALEGAGFVHYETSAFAKPAMQCRHNLNYWQFGDYLGIGA
                     GAHGKISYPDRIERTVRRRHPNDYLALMQSQPSEAVERKTVAAEDLPFEFMMNALRLT
                     DGVPAAMLQERTGVPSAKIMAQIETARQKGLLETDPAVFRPTEKGRLFLNDLLQC"
     gene            complement(1224..3749)
                     /gene="ligA"
                     /locus_tag="ACFOV4_001197"
     CDS             complement(1224..3749)
                     /gene="ligA"
                     /locus_tag="ACFOV4_001197"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFC7619213.1"
                     /translation="MNPNSKHNTNFTNLLKPSDSDIKQFAAQHICRLTDLLNRYAYEY
                     YTLDAPSVPDAEYDKLFRELEALELNHPELKLPDSPTQRVGGEPLAGFAEVRHEVPML
                     SLTNAFSPQDENGVFDHAEMYAFDQRVRDGLDGGKPEYVIEPKFDGLAISLLYRDGVL
                     VQAATRGDGTTGEDVTQNIKTVANIPLRLHGENTPELIEVRGEVLMQKADFAALNKRQ
                     AENGQKPFANPRNAAAGSLRQLDSRITAQRKLHFFPYSVARQQGGFVAEEHIQELAYF
                     QALGFSLPNGNFGCFKNIDEVLAFYEQMQQKRPELPYEIDGMVVKVNSLAQQRELGFI
                     SRAPRWAIAHKFPAEEALTIVEAIDVQIGRTGAVTPVARLQPVFVGGVTVTNATLHNQ
                     DEVSRKDVRVGDTVVVRRAGDVIPEVVRVIFERRPMQETAVAVSDGIGHRQDDLFAET
                     PSANQTQSVPLHKPYRLPTHCPICRSEIEREEGEAVARCSGGMLCQAQRAQGLIHFAS
                     RKAMDIDGLGEKQIEQLVAQDLVRHFADLYRLDIPTLQKMKETTDKTVAESDQTPSEG
                     SSVGASGKHKKQPVKWAENILGGIESGKTPELARFLFALGIRHVGERTAKTLAQAFGT
                     LERVRRAPEPILACLPDIGTVVAHSIAHFFAQAEQQAMIDELLAAGVAPQAQAVSLPA
                     AQYAEPQRWIARLPDFKISENKAQALWELAGKSIEGLQTDKSLPADWQAWRSEPQNAA
                     LLENLKTFFAQMPSEDEAAQGSDGINKAVAGKTFVLTGTLPTLKRDQAQSLIEAAGGK
                     VSGSVSKKTDYVVAGEAAGSKLEKANALGVSVLSEAELLTLLG"
     gene            complement(3897..5183)
                     /locus_tag="ACFOV4_001198"
     CDS             complement(3897..5183)
                     /locus_tag="ACFOV4_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA C-terminal
                     FtsZ-binding domain-containing protein"
                     /protein_id="HFC7619214.1"
                     /translation="MIYIVLFLAAVLAVVAYNMYQENQYRKKVRDQFGHSDKDALLNS
                     KTSHVRDGKPSGGSVMMPKPQPAVKKTAKLQDPAMRNLQEQDAVYIAKQKQAKASPFK
                     TEIETALEESGIIGNSAHTVSEPQTGHSAPKPADAPAKPAPVPQTPAKPLITLKELSK
                     VELPWFDVRFDFISYIALTEAKELHALPRLSNRCRYQIVGCTMDDHFQIAEPIPGIRY
                     QAFIVGIQAVSRNGLASQEELSAFNRQVDAFAQSMGGQTLHTDLAAFIEVASALDAFC
                     ARVDQTIAIHLVSPTSISGVELRSAVTGVGFVLEDDGAFHYTDTSGSTMFSICSLNNE
                     PFTNALLDNQSYKGFSMLLDIPHSPAGEKTFDDLFMDLAVRLSGQLNLNLVNDKMEEV
                     STQWLKDVRTYVLARQSEMLKVGIEPGGKTALRLFS"
     gene            complement(5377..5949)
                     /gene="ampD"
                     /locus_tag="ACFOV4_001199"
     CDS             complement(5377..5949)
                     /gene="ampD"
                     /locus_tag="ACFOV4_001199"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HFC7619215.1"
                     /translation="MDNHAEAHWQNGWLQSIRHTPSPNFSPRETGETVSLIVLHNISL
                     PPFEYGTDAVEKLFANRLDPDGHPFFSLIHTLRVSSHFLIKRDGETVQFVSCDNMAYH
                     AGVSSFRGREKCNAFSIGIELEGCDFEPFTEAQYRSLEALLDAICRRYPITAVTGHQD
                     IAPGRKTDPGHFFDWRRIRGKGFPVDRNAV"
     gene            6033..7028
                     /gene="mltG"
                     /locus_tag="ACFOV4_001200"
     CDS             6033..7028
                     /gene="mltG"
                     /locus_tag="ACFOV4_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFC7619216.1"
                     /translation="MLRKLLKWSAVFLTVSAAVFAALLFVPKDNGRAYRIKIAKNQGI
                     SSVGRKLAEDRIVFSRHVLTAAAYVLGVHNRLHTGTYRLPSEVSAWDILQKMRGGRPD
                     SVTVQIIEGSRFSHMRKVIDATPDIEHDTKGWSNEKLMAEVAPDAFSGNPEGQFFPDS
                     YEIDAGGSDLRIYQIAYKAMQRRLNEAWESRQDGLPYKNPYEMLIMASLIEKETGHEA
                     DRDHVASVFVNRLKIGMRLQTDPSVIYGMGAAYKGKIRKADLRRDTPYNTYTRGGLPP
                     TPIALPGKAALDAAAHPSGEKYLYFVSKMDGTGLSQFSHDLTEHNAAVRKYILKK"
     gene            7088..7708
                     /gene="tmk"
                     /locus_tag="ACFOV4_001201"
     CDS             7088..7708
                     /gene="tmk"
                     /locus_tag="ACFOV4_001201"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFC7619217.1"
                     /translation="MKPQFITLDGIDGAGKSTNLAVIKAWFERRGLPVLFTREPGGTP
                     VGEALREILLNPETKAGLRAETLMMFAARMQHIEDVILPALSDGIHVVSDRFTDATFA
                     YQGGGRGMPSEDIEILEHWVQGGLRPDLTLLLDVPLEVSMARIGQSREKDRFEQEQAD
                     FFMRVRSVYLNRAAACPERYAIIDSNRSLDEVRNNIEKVLDGHFGC"
     gene            7930..9210
                     /locus_tag="ACFOV4_001202"
     CDS             7930..9210
                     /locus_tag="ACFOV4_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malic enzyme-like NAD(P)-binding protein"
                     /protein_id="HFC7619218.1"
                     /translation="MENSLKEAALKFHELPVPGKISVTPTKSLATDKDLALAYSPGVA
                     APCMEIHADPQNAYKYTAKGNLVAVISNGTAVLGLGDIGALAGKPVMEGKGVLFKKFA
                     GVDVFDIEIDEKDPQKLVDIIAALEPTFGGINLEDIKAPECFYIERELRKRCKIPVFH
                     DDQHGTAIITAAAVLNALRFTGRKIEEATLVCSGAGAAAIACLNQLLDLGLKRENVTV
                     CDSKGVIYQTREDKDRMDESKKFYAVEDNGQRVLADAVKGKDIFLGLSGANLLTPEML
                     NTMNEKPIVFAMANPNPEILPPLAKETRPDVVIGTGRSDFPNQVNNVLCFPFIFRGAL
                     DVGATTINEEMKRACVYALADLAMEEVTEEVVAAYGKKFEFGAEYLIPTPFDSRLLPR
                     VATAAAKAAMESGVATRPIADLEAYAAKLSEWKL"
     gene            9446..9649
                     /locus_tag="ACFOV4_001203"
     CDS             9446..9649
                     /locus_tag="ACFOV4_001203"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619219.1"
                     /translation="MKEMKPVRYHIGDMPETSKQTASRHDDRAVGVDDDCFHDSFGQF
                     LFGCSAEATRTAPISVKRSCLFT"
     gene            9757..10791
                     /gene="lpxK"
                     /locus_tag="ACFOV4_001204"
     CDS             9757..10791
                     /gene="lpxK"
                     /locus_tag="ACFOV4_001204"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_025462052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009029 - tetraacyldisaccharide 4'-kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HFC7619220.1"
                     /translation="MPNCFKFHTVIERHWQKPYPVLSFLLKPLSGLFAKIAAKRRTDF
                     LSGKRQSEKLPVPVVVVGNIHAGGTGKTPIVAALVSGLQEKGVKVGIISRGYGRKSKA
                     VHVLNAESRAEDAGDEPLLLFRKTGAPTAVGSSRAEAGRALLAAHPDIGLIVADDGLQ
                     HYALRRDVEIAVFPAADTGRTDLDLLPNGSLREPLLRLDSVDAVVVSGGKADALFRPS
                     ENMFHSRIEAGRIYRLNNPSEILDTGRLKNQTVVAVAGIAKPARFFDSLRNMGITVKR
                     TVALPDHADISAADLPDADAVIITEKDAVKFSDGICTDNVWVLPVCAIIEPDLAAFVL
                     ERLEDVPKAV"
     gene            10997..11578
                     /locus_tag="ACFOV4_001205"
     CDS             10997..11578
                     /locus_tag="ACFOV4_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2059 domain-containing protein"
                     /protein_id="HFC7619221.1"
                     /translation="MKLKTLLLPFATLALCTNAFAAPPSDASLARWLDTQNFDRDIEK
                     NMIEGFNAGFKPYADKALAEMPEAKKDQAAEAFNRYRENVLKDLITPEVKQAVRNTLL
                     KNAREIYTQEEIDGMIAFYGSPVGQSVVAKNPRLIKKSMSEIAVSWTALSGKIARHHL
                     PAFTEELRRIICGGKNPDAGCKQAGQVGKRHQK"
     gene            11647..11829
                     /locus_tag="ACFOV4_001206"
     CDS             11647..11829
                     /locus_tag="ACFOV4_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trm112 family protein"
                     /protein_id="HFC7619222.1"
                     /translation="MEKKFLDILVCPVTKGRLEYHQDKQELWSRQAKLAYPIKDGIPY
                     MLENEARPLGEEELEA"
     gene            11826..12587
                     /gene="kdsB"
                     /locus_tag="ACFOV4_001207"
     CDS             11826..12587
                     /gene="kdsB"
                     /locus_tag="ACFOV4_001207"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HFC7619223.1"
                     /translation="MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAV
                     RVVVATDHPDIQTACQAHGVEVVMTSNRHESGTTRLAEASAALKLPPHLVVVNVQGDE
                     PLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAP
                     IPYPRDAMRAGKREMPFETAVLRHIGIYAYRVGFLQRYTEMRVSPLETIESLEQLRVL
                     WHGYPIAVETAKEAPAAGVDTQEDLDRIRAVFQTI"
     gene            12610..12927
                     /locus_tag="ACFOV4_001208"
                     /pseudo
     CDS             12610..12927
                     /locus_tag="ACFOV4_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237659.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
     gene            13029..13229
                     /locus_tag="ACFOV4_001209"
                     /pseudo
     CDS             13029..13229
                     /locus_tag="ACFOV4_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237659.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
     gene            13386..13478
                     /locus_tag="ACFOV4_001210"
     tRNA            13386..13478
                     /locus_tag="ACFOV4_001210"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13420..13422,aa:Ser,seq:gct)
     gene            13781..14566
                     /gene="trpA"
                     /locus_tag="ACFOV4_001211"
     CDS             13781..14566
                     /gene="trpA"
                     /locus_tag="ACFOV4_001211"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HFC7619224.1"
                     /translation="MSRIRQAFAALNGEKALIPYITVGDPDIGATLAIMHSMVENGAD
                     ILELGVPFSDPMADGPVIQRAAERALANGISLRDVLDVVRKFRETDTQTPVVLMGYLN
                     PVHKMGYREFAQEAAMAGVDGVLTVDSPVETIDPLYRELKDNGVDCIFLIAPTTTEDR
                     IKTIAELAGGFVYYVSLKGVTGAASLDTDEVSRKIEYLHQYIDIPIGVGFGISNAESA
                     RKIGRVADAVIVGSRIVKEIENNAGNEAAVVGALVKELKDAVR"
     gene            14603..15475
                     /gene="accD"
                     /locus_tag="ACFOV4_001212"
     CDS             14603..15475
                     /gene="accD"
                     /locus_tag="ACFOV4_001212"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFC7619225.1"
                     /translation="MSWLDKILPPKIKNRSKDGSSNVPEGLWHKCPSCSATVYSTELQ
                     QNNQVCPKCNHHNPLSARQRLNLLLDEDGREEVAGNVKPIDPLKFKDSKKYPDRLGAA
                     RKLTGEDDALVVMKGMMNGLPVVVAAFEFRFIGGSMGSVVGERFVQGVRRAVADNCPF
                     VCVAASGGARMQEGVNSLMQMTKTSAALHLLTEKRLPFISVLTDPTMGGVSASFAFLG
                     DVVLAEPNALIGFAGPRVIEQTVRETLPEGFQRAEFLLEKGAIDQIVDRRDMKRRISD
                     LITLLCRQDKVSAA"
     gene            complement(15535..16146)
                     /locus_tag="ACFOV4_001213"
     CDS             complement(15535..16146)
                     /locus_tag="ACFOV4_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNP1-like family protein"
                     /protein_id="HFC7619226.1"
                     /translation="MRRTALLLLALAAGTSLATSFSQKDTPINTRYRETPEEAAAREF
                     KEHTAKLPPLPDTHSDGWFDIYVDENYGKQPKILLDSLQIIPAPDGSIRYILNIRSDK
                     GYDNLTAEGIFCARFSIRFGNGKPSSYKVFGYGDTVNRRWIQPRNAEWKPIGGTLSRN
                     DALRTVLYQAFCEGGVPADTKGLVQRLKERAGRYAPSMKPHNK"
     gene            16255..16479
                     /locus_tag="ACFOV4_001214"
     CDS             16255..16479
                     /locus_tag="ACFOV4_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HFC7619227.1"
                     /translation="MNSETLDVTGLKCPLPILRAKKALAQMQQGDVLTVLATDGGVPG
                     DFEAFCRQTGHVLLDASEQDGVFTLVVQHK"
     gene            16480..16626
                     /locus_tag="ACFOV4_001215"
     CDS             16480..16626
                     /locus_tag="ACFOV4_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010791287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619228.1"
                     /translation="MPSEMRMSRPTALFLNIVCAACRFKNKPSGVQCRHFGRIAADLF
                     RNGC"
     gene            16842..17876
                     /gene="pyrC"
                     /locus_tag="ACFOV4_001216"
     CDS             16842..17876
                     /gene="pyrC"
                     /locus_tag="ACFOV4_001216"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_process: GO:0019856 - pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFC7619229.1"
                     /translation="MQTLTIIRPDDMHLHLRDGDALKAVAPYTARQMGRAVIMPNLKP
                     PVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDNATPELVREAKAAGIVAFKLYPA
                     GATTNSDSGVTDLFKLIPVLEEMAKQGILFLVHGEVTDPEIDIFDREAAFIGRVMKPV
                     LAQVPNLKVVFEHITTAEAVRLVLEAGDNVAASVTPQHLLLNRNDLLVGGVRPHHFCL
                     PVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAIELYA
                     EVFEKAGALDKLEAFASKNGARFYGIPENTDTITLVKQSQTVPASIPYGDGELVPMRA
                     GGEIGWTVQY"
     gene            complement(18242..18667)
                     /gene="nusB"
                     /locus_tag="ACFOV4_001217"
     CDS             complement(18242..18667)
                     /gene="nusB"
                     /locus_tag="ACFOV4_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFC7619230.1"
                     /translation="MKTARRRSRELAVQAVYQSLINRTAAPEIAKNIREMPDFAKADE
                     ELFNKLFFGTQTNAAEYIRQIRPLLDRDEKDLNPIERAVLLTACHELSAMPETPYPVI
                     INEAIEVTKTFGGTDGHKFVNGILDKLAAQIRPDEPKRR"
     gene            complement(18745..19221)
                     /gene="ribH"
                     /locus_tag="ACFOV4_001218"
     CDS             complement(18745..19221)
                     /gene="ribH"
                     /locus_tag="ACFOV4_001218"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HFC7619231.1"
                     /translation="MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVA
                     DENITVATVPGALEIPIALMNFASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSR
                     VALDYNIPIANAVLTTENDAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE"
     gene            complement(19269..19592)
                     /locus_tag="ACFOV4_001219"
     CDS             complement(19269..19592)
                     /locus_tag="ACFOV4_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HFC7619232.1"
                     /translation="MNAFAQALSSALDRCIATNTVAKQNQPVGFLYREAPVFENDSGW
                     RFFSGDETDEYTDDPDNFSIVSLADITKTNPETAALLSQPEGSAWELAEDGTFQTVAD
                     WQPQD"
     gene            19759..20478
                     /gene="rnc"
                     /locus_tag="ACFOV4_001220"
     CDS             19759..20478
                     /gene="rnc"
                     /locus_tag="ACFOV4_001220"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFC7619233.1"
                     /translation="MKDDVLKQQAHAAIQKRLGYAFRDISLLRQALTHRSHHAKHNER
                     FEFVGDSILNYTVARMLFDTFPKLTEGELSRLRASLVNEGVLAEMAAEMNVGDGLYLG
                     AGELKSGGFRRPSILADAMEAMFAAVSFDADFNTAEKVVRHLFADRVRCADFQNQAKD
                     GKTALQEALQARRFALPKYRIEEQIGHANDSMFVVSCDLGELGFVCRAKGTSRKAAEQ
                     EAAKEALKWLEEKLPLKKKKK"
     gene            20526..21449
                     /gene="era"
                     /locus_tag="ACFOV4_001221"
     CDS             20526..21449
                     /gene="era"
                     /locus_tag="ACFOV4_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004286080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFC7619234.1"
                     /translation="MDIETFLAGERAAGGYRCGFVAIVGRPNVGKSTLMNHLIGQKIS
                     ITSKKAQTTRNRVTGIYTDDTAQFVFVDTPGFQTDHRNALNDRLNQNVTEALGGVDVV
                     VFVVEAMRFTDADRVVLKQLPKHTPVILVVNKIDKDKAKDRYALEAFVAQVRAEFEFA
                     AAEAVSAKHGLRIANLLELIKPYLPESVPMYPEDMVTDKSARFLAMEIVREKLFRYLG
                     EELPYAMNVEVEQFEEEDGLNRIYIAVLVDKESQKAILIGKGGERLKKISTEARLDME
                     KLFDTKVFLKVWVKVKSGWADDIRFLRELGL"
BASE COUNT         4858 a         5367 c         6463 g         5206 t
ORIGIN      
        1 acattgcagc aaatcgttta aaaacaagcg tcctttttcg gtcgggcgga atacggcggg
       61 gtcggtttcc agcaggcctt tttgccttgc cgtttcgatt tgcgccatga ttttggcact
      121 cggtacgccc gtgcgctcct gcaacatcgc ggcgggtacg ccgtcggtca ggcgcagggc
      181 gttcatcatg aattcgaacg gcaaatcttc ggcagcgacg gttttgcgtt cgacggcttc
      241 actcggttgg ctttgcatta aggcgaggta gtcgttgggg tggcggcggc ggacggtgcg
      301 ctcgatgcgg tcgggatagg aaattttgcc gtgcgcgccc gcgcctatgc ctaaataatc
      361 gccgaactgc cagtagttca aattgtggcg gcactgcatg gctggtttcg caaaagccga
      421 tgtttcgtag tggacaaaac ccgcgccttc cagcgcgccg tgtaccgcgt cttcgatgtc
      481 gagggcggct tcgtcttgcg gcaaaccttt cggcggcgta tgaccgaacg gcgtgttcgg
      541 ttccatcgtc agatgatacg cgctgatgtg ggtcgcgccc gtagcgatag cggtttgtac
      601 gtcgtccaat gccgtctgaa cggtttggtt cggcagggca tacatcaagt cgatattgac
      661 tttatcaaat aatttcaagg cggtatcgat agcggttaag gcttccttac cgttgtggac
      721 gcgccccagc cttgagagca tatcgtcgtt gaaactctgt acgccgatag aaagccgcgt
      781 aatacccgcg tctttaaatc cttgaaactt ctcgatttca aatgtccccg gattggcttc
      841 caaggtaatt tccgcttccg gctgcaagcg caacagcgaa cgcacgccgc ttaacaaacg
      901 gtcaatcgat tccgcctgaa acaggctggg cgtaccgccg ccgaaaaaga tcgtttccac
      961 cggcctgccc caaatattgg gcaattcaag ctgcaaatcg gtcagcagcg cgtcgatata
     1021 ggcggcttcg ggcaatccgt ttttcaggct gtgggaattg aagtcgcaat acgggcattt
     1081 tttgatgcac cacgggatgt ggatgtaaag cgacaggggc ggcagggcgg tgagtcgggt
     1141 gcggtttgga aaggaaatgg tgtgcatggt gtggttcgga aaagtgggca atgccgtctg
     1201 aaggcggttc agacggcatg ggttcagccg agcagggtaa gcagttcggc ttcgctgagg
     1261 acggaaacgc ccaaggcatt ggctttttcc agcttgctgc ccgcggcttc tccggcgacg
     1321 acgtaatcgg tttttttgga cacgctgccg gaaactttgc cgcctgcggc ttcgattagg
     1381 gattgggctt ggtcgcgttt gagggtgggc agtgtgccag ttaacacgaa ggttttgccc
     1441 gctacggctt tattgatgcc gtctgaacct tgcgccgcct cgtcttcaga cggcatttgc
     1501 gcgaagaagg ttttcaggtt ttcgagtagg gcggcgtttt gtggttcgct gcgccatgct
     1561 tgccagtcgg cggggaggga tttgtcggtt tgcagaccct ctatactttt gccggcgagt
     1621 tcccataagg cttgggcttt gttttcgcta attttgaagt cgggcaggcg ggcgatccag
     1681 cgttgcggtt cggcatattg tgcggcaggc aggctgacgg cttgggcttg cggggcaacg
     1741 cctgcggcga gcagctcgtc tatcatcgcc tgctgttcgg cttgggcgaa gaagtgggca
     1801 atggaatgcg ccactaccgt gccgatgtcg ggcaggcagg cgaggatggg ttcgggggcg
     1861 cggcggacgc gttccaatgt gccgaatgcc tgcgccagcg ttttggcggt gcgttcgccg
     1921 acgtggcgga tgccgagcgc gaacaggaag cgcgcgagtt cgggcgtttt gccggattct
     1981 atgcccccga ggatgttttc cgcccacttg accggttgtt ttttatgttt gcccgacgcg
     2041 ccgaccgaac tgccttcaga cggcgtttga tccgattcgg caacggtttt gtccgtcgtt
     2101 tctttcattt tttgcagggt cggaatatcg aggcggtaga ggtcggcgaa gtggcggacg
     2161 aggtcttggg cgacaagctg ttcgatttgt ttttcaccca agccgtcgat gtccatggct
     2221 ttgcgcgagg cgaagtggat taagccttgc gcgcgttgtg cctgacaaag cataccgccg
     2281 ctgcatcggg cgacggcttc gccttcttcg cgttcgattt cgctgcggca gatggggcaa
     2341 tgggtcggca ggcggtaggg cttgtggagc ggaacggatt gggtttgatt agcggacggt
     2401 gtttcggcaa acaaatcgtc ctgccgatgc ccgatgccgt ctgaaacagc aacggcggtt
     2461 tcctgcatcg ggcggcgttc aaaaatcaca cgcacgactt cgggaatcac gtctccagcg
     2521 cggcgcacga cgacggtatc gccgacgcgc acgtcttttc gggaaacttc gtcctgattg
     2581 tgcagggtgg cgttggtaac ggttacgccg ccgacgaata cgggttgtaa tcgggcaacc
     2641 ggcgttaccg cgcccgtcct gccgatttgc acgtcaatcg cttcgacaat ggtcagggct
     2701 tcttcggcag ggaatttgtg ggcaatcgcc cagcgtggcg cgcgtgagat gaagccgagt
     2761 tcgcgctgtt gcgccaagct gttgactttg accaccatac cgtcgatttc gtagggcagt
     2821 tcggggcgtt tttgctgcat ttgttcgtaa aacgccaata cttcgtcgat atttttgaaa
     2881 cagccgaaat tgccatttgg cagactgaag ccgagtgctt ggaaataggc gagttcttgg
     2941 atgtgttctt ccgcgacgaa accgccttgc tggcgggcga cggagtaggg gaaaaagtgc
     3001 agtttgcgtt gcgcagtgat gcgcgaatcg agttggcgca ggctgccggc agcggcgttg
     3061 cgcggattgg caaagggttt ttgcccgttt tcggcttgtc ttttattgag ggcggcaaaa
     3121 tcggcttttt gcatcagtac ttcgccgcgt acttcgatga gttcgggcgt attttcgccg
     3181 tgcagccgca gggggatgtt ggcgacggtt ttgatgtttt gggtaacgtc ttcgcccgtt
     3241 gtgccgtcgc cgcgcgttgc cgcctgtacc aatacgccgt cgcggtagag caggctgatg
     3301 gcgaggccgt cgaatttggg ttcgataacg tattcgggtt tgccgccgtc caagccgtcg
     3361 cgcacgcgtt ggtcgaaggc gtacatttcg gcatggtcga acacgccgtt ttcatcttgc
     3421 ggggaaaaag cgttggtcag cgacagcatc ggcacttcgt ggcgtacttc ggcaaatccc
     3481 gccaaaggct cgccgccgac gcgctgggtc gggctgtcgg gcagtttgag ctcgggatgg
     3541 tttaactcca acgcttcgag ttcgcggaac aatttgtcgt attcggcatc gggtacgctg
     3601 ggcgcgtcga gggtgtagta ttcgtaggcg tagcggttga ggaggtcggt gaggcggcag
     3661 atgtgttgtg cggcaaattg ttttatatca ctatcagacg gtttaagaag attggtaaag
     3721 ttagtgttat gttttgagtt tggattcatg agagaaggtt ttcagacgac ctttgtctga
     3781 tacgggatga aacgggcaaa ggtcgtctga aaaatgatag gttgaaaaca gctgaatttt
     3841 acccgaaaaa aagcggatat gccgtaacga catatccgct ttgattgcat tcgattttag
     3901 gagaacaggc gcaatgcggt tttgccgccc ggttcgatac cgactttgag catctcggac
     3961 tgacgcgcca atacataagt gcgcacgtct ttgagccatt gggtcgaaac ttcttccatt
     4021 ttgtcgttga ccagattcag gttcaactgg ccggacaggc gtaccgccaa atccataaac
     4081 aaatcgtcga aggttttttc gcctgccgga gagtgcggga tgtcgagcag catactgaag
     4141 cctttgtagg actggttgtc caaaagggcg ttggtaaacg gctcgttgtt gagcgagcag
     4201 atggagaaca tggtcgagcc cgacgtgtcg gtatagtgga acgcgccgtc gtcttccaaa
     4261 acgaaaccca cgcccgttac ggcggaacgc agttctacgc cgctgatgct ggtcggggaa
     4321 accaaatgga tggcgatggt ctggtcgacg cgcgcgcaga atgcgtccag tgcggaagcc
     4381 acttcgataa aggcggcaag gtcggtgtgc agcgtctgac cgcccatgct ttgtgcgaat
     4441 gcgtccacct ggcggttgaa tgcggagagt tcttcctgcg aggcaagtcc gttgcggctg
     4501 actgcctgaa tacccacgat aaatgcctga tagcggatgc ccgggatggg ttcggcaatc
     4561 tggaaatggt cgtccatggt gcagccgaca atctggtagc ggcagcggtt ggaaaggcgc
     4621 ggcagtgcgt gcagttcttt ggcttcggtc agcgcgatat aggagatgaa gtcgaagcgc
     4681 acgtcaaacc agggtaattc gacttttgac agttctttga gcgtaatcag cggttttgca
     4741 ggtgtttgcg gaacgggtgc aggttttgcc ggcgcgtcgg caggtttcgg tgcggaatgt
     4801 ccggtttggg gttcggaaac ggtgtgggcg gagttgccga taatgccgct ttcttccaag
     4861 gcggtttcga tttcggtttt gaacggggag gcttttgcct gtttctgctt ggcgatgtag
     4921 acggcatcct gttcttgcag gttgcgcata gcagggtctt ggagttttgc cgtttttttg
     4981 accgccggtt ggggtttcgg catcatgact gacccgccgg acggtttgcc gtcgcggaca
     5041 tggctggttt tgctgttgag cagggcatct ttgtcggagt gtccgaactg gtcgcgcact
     5101 tttttgcggt attggttttc ctgatacata ttgtaggcga caacggcgag gacggcggcg
     5161 aggaacagta cgatgtaaat catggcaatc actttaaatt tcgggatgca ggatgcgcga
     5221 agtgcgggta ctgcggttaa atcgggcttg cgtttccggc agtctgatgg aacggccggt
     5281 tataacgttt gaattataac gaaaattgca gggtctgaca gcagtgtgtc gaaataagcg
     5341 gaaattttcc gaaatgccgt ctaaaatctg tggttttcag acggcatttc tgtccacggg
     5401 aaaccctttc ccccgtatcc gccgccagtc gaaaaaatga ccggggtcgg ttttgcggcc
     5461 gggcgcgatg tcttggtgcc ccgttaccgc cgtgatgggg tagcggcggc agattgcgtc
     5521 caacaaggct tcgagcgaac ggtattgcgc ttcggtaaag ggttcgaaat cgcagccttc
     5581 cagttcgatg ccgatggaaa atgcgttgca tttttcccgt ccacgaaacg aggatacgcc
     5641 ggcatggtat gccatattgt cgcaggaaac gaactgtacc gtttcgccgt cgcgtttgat
     5701 taaaaaatgg ctggatacgc gcaaagtgtg tatcaggctg aagaacggat gtccgtcggg
     5761 gtcgagccgg ttggcaaaca gcttttccac cgcatccgta ccatattcga acggcggcag
     5821 cgaaatgttg tgcaacacga tcagggaaac cgtttccccc gtttccctcg ggctgaaatt
     5881 gggcgacggg gtatggcgta tgctttgaag ccagccgttt tgccagtgtg cttcggcgtg
     5941 attgtccatg atgttcttcc tgtccggcgg gcaatttggg ttatactgtc gcccgaattt
     6001 taagacgtat tccgaatgct gggaatccta ccatgttgag aaaattgttg aaatggtctg
     6061 ccgttttttt gaccgtatcg gcagccgttt tcgccgcgct gcttttcgtc cctaaagaca
     6121 acggcagggc atacaggatt aaaattgcca aaaaccaggg tatttcgtcg gtcggcagga
     6181 aacttgccga agaccgcatc gtgttcagca ggcatgtttt gacggcggcg gcctacgttt
     6241 tgggtgtgca caacaggctg catacgggga cgtacagact gccttcggaa gtgtctgctt
     6301 gggatatctt gcagaaaatg cgcggcggca ggccggattc cgttaccgtg cagattatcg
     6361 aaggttcgcg tttttcgcat atgaggaaag tcatcgacgc aacgcccgac atcgaacacg
     6421 acaccaaagg ctggagcaat gaaaaactga tggcggaagt tgcccctgat gccttcagcg
     6481 gcaatcctga agggcagttt ttccccgaca gctacgaaat cgatgcgggc ggcagcgatt
     6541 tacggattta ccaaatcgcc tacaaggcga tgcaacgccg actgaatgag gcatgggaaa
     6601 gcaggcagga cgggctgcct tataaaaacc cttatgaaat gctgattatg gcgagcctga
     6661 tcgaaaagga aacagggcat gaagccgacc gcgaccatgt cgcttccgtc ttcgtcaacc
     6721 gcctgaaaat cggtatgcgc ctgcaaaccg acccgtccgt gatttacggc atgggtgcgg
     6781 catacaaggg caaaatccgt aaagccgacc tgcgccgcga cacgccgtac aacacctaca
     6841 cgcgcggcgg tctgccgcca accccgatcg cgctgcccgg caaggcggca ctcgatgccg
     6901 ccgcccatcc gtccggtgaa aaatacctgt atttcgtgtc caaaatggac ggtacgggct
     6961 tgagccagtt cagccatgat ttgaccgaac acaacgccgc cgttcgcaaa tatattttga
     7021 aaaaataaac catgccgtct gaaaagtttg tgttttcgga cggcataccc ttaccggaac
     7081 tgcaagcatg aaaccgcaat tcatcacttt ggacggcata gacggtgccg gcaaatccac
     7141 caaccttgcc gtcatcaagg catggtttga acggaggggg ctgcccgtgc tgttcacgcg
     7201 cgaaccgggc ggaacgccgg tcggtgaggc cttgcgcgaa atcctgctca accctgaaac
     7261 caaagccggt ttgcgtgcgg aaacactgat gatgttcgcc gccagaatgc agcatattga
     7321 agacgtgata ttgcctgcac tttcagacgg catccatgtc gtgtccgacc gttttaccga
     7381 cgcaaccttc gcctatcagg gcggcgggcg ggggatgccg tctgaagaca ttgaaatttt
     7441 ggaacattgg gtgcagggcg gtttgcgccc cgatttgacc ctgctgttgg atgtgccgct
     7501 ggaagtgtcg atggcgcgta tcggacagtc gcgcgagaaa gaccggttcg agcaggaaca
     7561 ggcagatttc ttcatgcgtg tgcgcagcgt ttatctgaac cgtgccgccg cctgtcccga
     7621 acggtacgcc attatcgaca gtaaccgcag cttggatgaa gtcagaaaca acatagaaaa
     7681 agtgttggac ggacatttcg gctgttaatg cggcaaatat tgaaacaagc gcatccaccc
     7741 gcgccgaaaa tcaaacggca gtgccgcagg tgaaaatggc ggtatgcgcc aaactttcgg
     7801 catgatagaa ttacgctcgg ttacaaggca ggatgcgtcg gcaatattaa cgaaccgccc
     7861 gtaacatgat gacccgaaag cgtttcggac agtccgattc aaatcttttt ctcgcaacag
     7921 gattgacaca tggaaaactc attgaaagaa gccgccctca agttccacga attacccgtt
     7981 ccgggcaaaa tttccgttac cccgaccaaa tctttggcga ccgacaaaga tttggcgttg
     8041 gcgtactctc cgggcgtagc cgctccttgt atggaaatcc atgccgatcc gcaaaatgcc
     8101 tacaaataca ccgccaaagg caacttggtc gccgtcattt ccaacggtac ggccgttttg
     8161 ggcttgggcg acatcggcgc gctggcgggc aaacccgtga tggaaggtaa aggcgtattg
     8221 ttcaaaaaat tcgccggtgt ggacgtgttc gacatcgaaa tcgatgaaaa agacccgcaa
     8281 aaactcgtgg acatcatcgc cgctttagag ccgaccttcg gcggcatcaa cctcgaagac
     8341 atcaaagcac ccgagtgttt ctacatcgaa cgcgaattac gcaaacgctg caaaatcccc
     8401 gtattccacg acgaccagca cggcacggcc atcattaccg ccgccgccgt attgaacgcc
     8461 ctgcgtttta ccggccgtaa aatcgaagaa gcgactttgg tgtgttccgg cgcaggtgcg
     8521 gccgcgattg cctgcttgaa ccaattgctg gatttgggct tgaaacgcga aaacgtgacc
     8581 gtttgcgact ccaaaggcgt gatttaccaa acccgcgaag acaaagaccg catggacgaa
     8641 tccaaaaaat tctacgccgt tgaagacaat ggccagcgcg tacttgccga tgccgtcaaa
     8701 ggtaaagaca tcttcttggg cctctccggc gcgaacctgc tgacccccga aatgttgaac
     8761 acgatgaacg aaaaacccat cgtgttcgcc atggccaacc cgaatccgga aatcctgccg
     8821 ccgctggcga aagaaacccg tccggacgtg gttatcggta ccggccgctc cgacttcccg
     8881 aaccaagtga acaatgtatt gtgcttcccg ttcatcttcc gcggtgcgtt ggatgtcggc
     8941 gcgacgacca tcaacgaaga aatgaaacgc gcctgcgtgt atgctttggc ggatttggcg
     9001 atggaagaag taaccgaaga agtggttgcc gcttacggta agaaatttga attcggcgcg
     9061 gaatacctga ttccgactcc gttcgattcc cgcctgctgc cgcgcgttgc tacggctgcc
     9121 gccaaagcag cgatggaaag cggcgtggca acccgtccga ttgcagattt ggaagcttac
     9181 gctgccaagc tgagcgaatg gaagctgtaa gccgtttgcg gtttaaaatg ccgtctgaac
     9241 tgttttcagg cggcattttg ctgtcagatt gatatagtgg attaacaaaa atcaggacaa
     9301 agcgacgaag ccgcagacag tacaaatagt acggaaccga ttcacttggt gcttcagcac
     9361 cttagagaat cgttctcttt gagctaaggc gaggcaacgc tgtactggtt tttgttaatc
     9421 cactataaat gaaagatact ggaaaatgaa agagatgaaa cctgtccgtt atcatattgg
     9481 cgatatgccc gagacttcaa aacaaaccgc ctcccgtcat gacgacaggg cagtgggtgt
     9541 tgacgatgat tgttttcatg attcctttgg tcaatttttg tttgggtgtt cggcagaggc
     9601 aacccgaacc gcgccaattt ctgtaaagcg cagttgctta tttacctgat tggttcgctt
     9661 atcggtttgg tcttcgcgtt gtttataggt gggtctgtat cgggtacgca tgattaatgc
     9721 cccgggctga ttttgcttcg aggatttgta tcgaatatgc cgaattgttt caaatttcat
     9781 actgttatcg aacggcattg gcaaaaacct tatccggttt tgtcttttct gcttaagccg
     9841 ctctccgggc tgtttgccaa aattgcggca aaacggcgga cggatttttt atcgggaaaa
     9901 cggcaaagcg aaaagctgcc cgtgcctgtg gtcgtggtcg gcaatattca cgcgggtggg
     9961 acggggaaaa cgccgattgt tgccgcgctg gtgtcgggtt tgcaggaaaa gggcgtcaag
    10021 gtcggcatca tcagccgggg ctacgggcgc aagagcaagg cggttcatgt attgaatgct
    10081 gagagccgag cggaagatgc gggcgatgag cctttgctgc tgttccgcaa aaccggtgcg
    10141 ccgacggcgg tgggcagcag ccgtgcagag gcaggcaggg cgttgctggc ggcgcatccc
    10201 gacatcggac tgattgtggc ggacgacggt ttgcagcatt acgccctgcg gcgagatgtg
    10261 gaaatcgcgg tgtttccggc ggcggatacg gggcgcacgg atttggattt actgcccaac
    10321 ggcagtttgc gcgaaccttt gttgcggctg gattcggtgg atgcggtcgt cgtcagcggc
    10381 ggcaaggcgg atgcgctgtt taggccgtct gaaaatatgt ttcacagccg tatcgaagcg
    10441 ggacggattt accgtttgaa caatccgtcc gaaatactgg acacaggccg tctgaaaaat
    10501 caaaccgtcg tcgccgtggc aggtattgcc aagccggcgc gttttttcga ttcgttgcgg
    10561 aatatgggca ttaccgtgaa gcgaaccgtc gcgctgcccg accacgccga catttcggcg
    10621 gcagatttgc ccgatgcgga cgcggtcatt attacggaga aagatgcggt caaattttca
    10681 gacggcattt gcaccgataa tgtttgggtg ttgcccgttt gtgcgataat cgaacctgat
    10741 ttggcggcgt ttgtgttgga gcggttggaa gatgtaccga aggccgtctg aaagcacggt
    10801 ttgggcggag tgattacgga tttgaataag aacgcctcgc gccgtcattc ccgcgcaggc
    10861 gggaatctaa gtctcgaatt ttcaggaatg cctaggaggc ttcagaaatc ccaaatctcc
    10921 ggatttccac ttggacagga atgagaaaat cggtcgtatt ttttatctgc attaatcatt
    10981 cgttaaagta ttgaatatta aactgaaaac cttgttattg cccttcgcca cgctggcatt
    11041 gtgcaccaac gcttttgccg ccccgcctag cgacgcgtcg ttggcgcgtt ggctggatac
    11101 gcagaatttt gaccgggata tagaaaaaaa tatgattgag ggctttaatg ccggatttaa
    11161 accgtatgcg gacaaagccc ttgccgaaat gccggaagcg aaaaaagatc aggcggcaga
    11221 agcctttaac cgttatcgtg agaatgtttt gaaagatttg attacgcccg aagtgaaaca
    11281 ggctgtccgt aatactttat tgaagaatgc ccgtgagata tacacgcaag aagaaattga
    11341 cggcatgatt gccttttacg gttcgcctgt cggtcagtcc gtcgttgcca aaaatccgcg
    11401 cttaatcaag aaatcgatga gtgaaatagc agtatcttgg actgcattgt cagggaaaat
    11461 cgcgcgacat catctgcccg cgtttacgga agagttgcgg cgcatcatct gcggcggtaa
    11521 aaatcccgat gcgggctgta aacaagccgg acaggttggg aaaaggcatc agaaataaat
    11581 gatagccgtc tgaaatattg aagagggcat ccgattgatt gaaccatcaa acccgaaagc
    11641 aaccctatgg aaaaaaaatt cttagacatc ctcgtctgcc ccgttaccaa aggcaggctg
    11701 gaatatcatc aggacaaaca ggaattgtgg agccgtcagg cgaagcttgc ctatccgatt
    11761 aaagacggca ttccctatat gctggaaaac gaagcgcgtc cgttgggcga agaggaactc
    11821 gaagcatgac cgaattcgtc gtattgattc cggcgcggct ggattcgtcg cgcctgcccg
    11881 gaaaagcctt ggcggacatc cacggcaaac cgatggtcgt gcgcgttgcc gaacaggcgg
    11941 caaaaagtaa agctgtgcgc gtcgtcgttg ccaccgacca tcccgatatt cagacggcct
    12001 gtcaggcgca cggcgtcgaa gtcgtcatga cttcaaaccg gcacgaaagc ggcacgacgc
    12061 gccttgccga agcctctgcc gcgctgaagc tgccgccgca tctggtggtt gtcaacgtac
    12121 agggcgacga gccgctgatt gcacctgaac tcatcgaccg caccgccgaa gtactcgtcg
    12181 aaaacaacgt ccaaatggcg accgccgccc acgaattgca cgatttcgac gaattgatga
    12241 atcccaatgc cgtcaaagtt gtcctcgaca aaaaccgcaa cgccatctac ttcagccgcg
    12301 ccccgattcc ctatccgcgc gatgcgatgc gtgcaggaaa acgcgaaatg ccgtttgaaa
    12361 ccgccgtcct gcgccatatc ggcatctacg cctaccgcgt cggcttcctg caacgctaca
    12421 ccgaaatgag agtttcgccg ctggaaacca ttgaatcgct ggagcaactg cgtgtcctgt
    12481 ggcacggcta cccgattgcc gtcgaaaccg ccaaagaagc tcctgccgcc ggcgtagata
    12541 cgcaggagga tttggacagg attcgcgctg tatttcagac tatataaaat agattcaaag
    12601 ggaaaagata tgcagcaaca tattgaaaaa tggcaacact tgagccggga agaacagaaa
    12661 atccttgctg aagtatgggg tctcgtgcaa aacgacgatc aggaggttca ctatgaaatg
    12721 ctcaaattga acgcacccga cgaagccagt ggcgaatttt ggttcagaat ggcagaaaca
    12781 ctcagcaccc tgccgcccaa ccgttccctc gaccttagaa tgaacggcgg caggctggcg
    12841 accgccgtat ccatcctttc cgtcatgatt gaagacaatc ccgacatacc gcagctttgg
    12901 gcgcaaaaaa ttaccgcgct caattatagt ggattaaatt taaaccagta cggcgttgcc
    12961 tcgccttgtc gtactatctg tactgtctgc ggcttcgtcg ccttgtcctg atttttgtta
    13021 atccactata tttggcacac ggacacaaag cccgtgccga cggtttggca caacagcccg
    13081 acaaagcggc agaagccaac gaggaggaat acctgaccaa agccctgtcg caaaacctac
    13141 tgtcaacatt ggatgccgcg cttgcacgtt ttcctgaaga cgcgtggttt caggaaatca
    13201 aacaggatgc acaaaagcat tttgcttgag gatgtggcag tcaggaatat ttccattcag
    13261 gaagaaaaga agtgcctgat tgggtataat cagggtaaat cttattttat ttcaaaagat
    13321 taatatttgc tttctgtttt tccttgacgg tatcggaaaa gttgattata gttacagctt
    13381 ccttaggagt aatggctgag aggctgaagg cacttccctg ctaaggaagc atgtggggtc
    13441 aacctgcatc gagggttcga atccctctta ctccgccaag atgagaagac gctgtgtttt
    13501 acagcgtctt tttttacgcg ctttgttgcg gaagtgccga gggctgtctg ccgtgcgccg
    13561 cctggatttg caatgtgccc gcccgtgcaa aatccgattt gaccaacctg aagggcaggt
    13621 ttcggaagag cggggaattt tgataaacaa aaaactgcac ggcataatct ttcccggttt
    13681 tcattttccg tattcgccta tccgtaccgc aaatgctata ctgggaaaaa tttaccgatt
    13741 gtgttttacg gcatatttgc cgataggatg gaagagacaa atgagcagaa tccggcaggc
    13801 ttttgccgct ttaaacggtg aaaaggcatt gattccttat attacggttg gagacccgga
    13861 cattggggcg actttggcaa taatgcacag tatggtggaa aacggtgcgg atattttgga
    13921 gttgggcgtg ccgttttccg atccgatggc ggatggaccg gttattcagc gtgcggcgga
    13981 gcgggcgttg gcaaacggga tttcgctgcg cgatgtcttg gatgtcgtca gaaaattccg
    14041 tgaaaccgac acgcaaacgc cggttgtttt gatgggatat ttgaaccctg tacataagat
    14101 gggttatcgg gagtttgctc aggaagccgc aatggcgggt gtggacggcg tgttgacggt
    14161 ggattcccct gtcgaaacca tcgatccgct ctatcgcgag ctgaaggata acggggtcga
    14221 ctgtattttc ctgattgcgc cgacgacgac ggaagaccgt attaaaacca ttgccgagct
    14281 ggcaggcgga tttgtctatt atgtttcgct caagggcgta acgggcgcgg caagtttgga
    14341 tacggatgag gtttcgcgta aaatagagta tttgcatcag tatatcgata ttcccatcgg
    14401 tgtcggtttc ggcatcagca atgcggaaag cgcgcgcaaa atcggccggg ttgccgacgc
    14461 ggtcattgtc ggcagccgga ttgtgaaaga gattgaaaac aatgcgggca acgaggctgc
    14521 ggtcgtcggt gctttggtca aagagttgaa ggatgccgtg cgctgattct gtcacgcatt
    14581 ctaaatattt taggagttgt ccatgagctg gttagataaa atcctgccac ccaaaatcaa
    14641 aaaccgcagc aaagacggtt cttccaatgt tcccgagggt ttgtggcaca aatgtccgtc
    14701 ttgttcggca accgtttatt cgaccgagtt gcagcagaac aatcaggttt gtccgaaatg
    14761 caaccaccac aatccgttgt cggcacgaca acgcctgaac ctgcttttgg atgaggatgg
    14821 cagggaggaa gttgccggaa atgtcaaacc gatagatcct ttgaagttta aagacagtaa
    14881 aaaatatccc gaccgtttgg gggcggcacg caagctgacc ggggaagatg acgcgctggt
    14941 ggtgatgaag gggatgatga acggcctgcc cgtcgtcgtt gctgcgtttg aattccgctt
    15001 tatcggcggt tcgatgggtt cggttgtggg agagcgtttc gtacagggcg tccgccgtgc
    15061 ggttgccgac aattgtccgt tcgtctgtgt ggcggcttcc ggcggtgcgc gtatgcagga
    15121 gggtgtgaac tcgttgatgc agatgacgaa aaccagtgcc gcgctgcatt tgctgacgga
    15181 aaaacgcctg ccgtttatat cggtattgac cgatccgact atgggcggcg tatccgccag
    15241 cttcgcattt ttgggtgatg ttgtgcttgc cgaaccgaac gcgctgatcg gttttgccgg
    15301 tccgcgcgtg attgagcaga cggtgcgcga aacgctgccg gaaggcttcc aacgcgccga
    15361 gttcctgctg gaaaaaggcg caatcgacca gattgtcgac cgccgcgata tgaagcggcg
    15421 catcagtgat ttgattacgc tgttgtgccg tcaggacaaa gtttccgccg cttgatggct
    15481 gatgaatcga ataccgtctg aaaccgatgt ttcagacggt atttttgtgt ctggttattt
    15541 gttgtgcggc ttcatcgacg gggcatagcg tccggcacgt tctttcaggc gttgtaccaa
    15601 acctttcgtg tcggcgggta caccgccctc gcagaatgcc tgatacagga cggtgcgcag
    15661 tgcgtcgttg cggcttaatg taccgcctat cggtttccat tcggcgtttc ggggctgtat
    15721 ccagcggcgg ttgaccgtgt cgccgtagcc gaacacttta taggaggaag gtttgccgtt
    15781 gccgaacctg atggagaagc gggcgcagaa tatgccttcg gcagtcaggt tgtcgtagcc
    15841 tttgtcggag cggatattga gaatgtagcg gatgctgccg tcgggcgcgg gtataatttg
    15901 caggctgtcg agcaggattt tcggctgttt gccgtaattt tcatccacat aaatgtcaaa
    15961 ccagccgtcc gagtgcgtat cgggcagcgg cggcagtttg gcggtatgtt ctttaaattc
    16021 gcgggcggcg gcttcttcgg gcgtttcgcg gtagcgggtg ttgatcggcg tgtctttttg
    16081 gctgaagctg gtggcaaggg acgtgccggc ggcgagtgcg agcagcagga gggcggtgcg
    16141 gcgcataagt ttctccaaat tgaaaacggc gttattttat gggttggcaa agggggctgc
    16201 aagcaactgg ggtataatct ccccccgatt cccatttttt aaacggtaca aacgatgaac
    16261 agcgaaactt tagacgtaac cggattgaaa tgtcccctgc cgattttgcg ggcgaaaaag
    16321 gctttggcgc aaatgcagca gggcgacgtg ttgaccgttc tggcaaccga cggcggcgta
    16381 ccgggggatt ttgaggcttt ttgccgccaa accggtcatg tgctgttgga tgcttccgaa
    16441 caggacggcg tgttcacgct ggtcgtccaa cacaaataaa tgccgtctga aatgcggatg
    16501 tcccgcccga cggcgttgtt tttgaatatc gtatgtgccg cgtgccgttt caaaaacaaa
    16561 ccgtccggcg tgcagtgtcg gcatttcggg cgtatcgccg ccgatttgtt ccggaatggc
    16621 tgttaaccgc cttgccgtcg gcaaagaagc aaaacccaag cacaatcaaa atctaaaggc
    16681 tgtgtttgaa gattccgttg atgcaaccca atcagtcgga caaaatgcct ttcatccaat
    16741 ggaaccggtt tccgaccgga cggaataacc ggctttcccc cggcaaacgg atggaatcga
    16801 ccgggtattc aaacgcagcc aaaacctaaa aaggaacaac catgcaaacc ctgaccatta
    16861 tccgccccga cgatatgcac ctgcacctgc gcgacggcga cgcgctcaaa gccgttgctc
    16921 cttataccgc ccgccaaatg gggcgcgccg tcatcatgcc caacctcaaa ccgcccgtcg
    16981 tcagcgtagc cgatgcgctt gcctacaaag cgcgtattat ggcggcgttg cccgaaggca
    17041 gcgcgtttga gccgctgatg acgctttatt tgaccgacaa cgccacgccc gaactcgtgc
    17101 gcgaagccaa agccgccggc atcgtcgcct tcaaactcta ccctgccggc gcgaccacca
    17161 attccgattc cggcgtaacc gacctgttca aactcatccc cgttttggaa gaaatggcaa
    17221 aacagggcat cctgttcctc gttcacggcg aagtaactga ccccgaaatc gacatcttcg
    17281 accgcgaagc cgcctttatc gggcgcgtga tgaaacccgt tttggcgcaa gtgccgaatc
    17341 ttaaagtcgt gttcgaacac atcaccaccg ccgaagccgt ccgccttgtt ttggaagcgg
    17401 gcgacaacgt tgccgcctcc gtgaccccgc aacacctcct gctcaaccgc aacgacctct
    17461 tggtcggcgg cgtgcgcccc catcatttct gcctgcccgt actcaaacgc gaaacccacc
    17521 gtcaggcatt ggttgccgcc gttaccggcg agaaggcgca taaattcttc ctcggcaccg
    17581 actccgcgcc gcacgccaaa tccgccaaag aaaacgcctg cggttgcgcc ggtatgttca
    17641 gcgcgatgac cgccatcgag ctttatgccg aagtgtttga aaaagcaggc gcgttggaca
    17701 aactcgaagc cttcgcctcg aaaaacggcg caaggtttta cggcattcct gaaaataccg
    17761 acacgatcac cctcgtcaaa caaagccaaa ccgtccccgc aagtattccc tacggcgacg
    17821 gcgaacttgt cccgatgcgc gcgggcggcg aaatcggctg gacggtacag tattgatggg
    17881 gctggaaaca aaatgccgtc tgaaaggttt ttcagacggc atttgtgttg ttgactgatt
    17941 gatacgtcaa cggcgtttga gtttgttacg tttcggttat ttccgataaa ttcccacaat
    18001 tttcaaattt cgccattccc acgaaggcag gaatccggaa attcgatgcg accagagttt
    18061 atcaaaaacg gcagcaactc aaaaaaccgg attcccgcct gcgcgggaat gacgagattg
    18121 aagtttcaga atttatttga aatacccaaa attcaaaaaa ccaaattccc acctgcgtgg
    18181 gaatgacgaa acaaagaaag cagaaataag gacatagaac tttctttaaa tttgtgatgc
    18241 atcaacggcg tttgggctcg tcgggacgga tttgggcggc gagtttgtcg aggatgccgt
    18301 tgacgaattt gtgcccgtcc gtgccgccga aggttttggt tacttcgatg gcttcgttga
    18361 tgatgacggg gtagggcgtt tcgggcatgg cggacagctc gtggcaggcg gtcagcagga
    18421 cggcgcgttc gatggggttg aggtcttttt cgtcgcggtc gagcaggggg cggatttgtc
    18481 ggatgtactc tgccgcattg gtttgcgtgc cgaagaaaag tttgttgaac aattcttcgt
    18541 ctgccttggc aaagtcgggc atttcgcgga tgtttttagc aatctcgggc gcggcggtgc
    18601 ggttgataag ggattggtaa acggcttgta cggcaagctc gcgggaacgg cggcgggctg
    18661 ttttcatgat ttttccttga aacggttggg cggcacggta tgccgtctga aacggaaagg
    18721 gcgtatcggt gtacgccctg tttgttattc ttcgtcttca aactgttctt cgagcaggag
    18781 gttgacgagg ttggcgcatt ctacggcgac tttggcggca tccgaggctt tttcttcaat
    18841 ccgttcgatt gcctgtgcgt cgttttccgt ggtcaggacg gcattggcaa tcgggatgtt
    18901 gtagtcgagt gcgacgcggc tgacccctgc tccggattcg ttggaaacca gctcgaaatg
    18961 gtaggtttcg ccacggataa cgacgccgat ggcaatcagt gcgtcaaatt tttcagaaga
    19021 ggcaaagttc atcagcgcga tggggatttc aagcgcgccg ggtacggtgg cgacggtaat
    19081 gttttcgtct gccacgccca attcttggag ggtgcggcag cagactttga gcatttcgct
    19141 gccgatttcg ttggtgaagc gtgcctgtac gatgccgatg cggaggtgtt tgccgtcgag
    19201 gttgggggcg atggtgttca ttgggtgtcc tttggtattc ggaggtttcg gaatgccgtc
    19261 tgaaggtttt agtcttgcgg ctgccagtcg gcgacggttt ggaatgtgcc gtcttctgcc
    19321 aattcccacg cgctgccttc aggttgggag agcagtgcgg cggtttcagg gttggttttg
    19381 gtgatatcgg cgaggctgac gatgctgaag ttgtccgggt cgtcggtgta ttcgtcggtc
    19441 tcgtcgccgc tgaagaaacg ccagccgctg tcgttttcaa aaacgggggc ttcgcggtag
    19501 aggaagccga cgggctggtt ttgtttggcg acggtgttgg tggcgatgca gcggtcgagt
    19561 gccgaggaaa gtgcttgtgc aaatgcgttc attgcgggaa tacgttgggg gaaaacttgc
    19621 ggattttacc acgattcttg cgttgtcggc agacggcggc ggtttggtgg tacaatgtgc
    19681 gccgtttgca gccttaaggt gtttctgtat ttttggagta tggaaacgca ttcgggctgt
    19741 tttttgcgga agacggtaat gaaagacgat gttttgaaac agcaggcaca cgcggcgata
    19801 cagaagagac tgggctacgc gttccgcgat atttcgcttt tgcggcaggc tttgacgcac
    19861 aggagccatc atgcgaagca caacgagcgg ttcgagtttg tcggtgattc gattttgaat
    19921 tatacggtgg cgcggatgct gtttgacacg tttccgaagt tgaccgaggg cgagttgtcg
    19981 cggttgcggg caagtctggt caatgagggc gtgctggcgg aaatggcggc ggaaatgaat
    20041 gtcggcgacg gtctgtactt gggggcgggc gagttgaaga gcggcggctt cagacggcct
    20101 tcgatactgg cagacgcgat ggaggcgatg tttgcggcgg tcagcttcga tgccgatttc
    20161 aacacggcgg aaaaggtggt gcgccatttg tttgccgacc gcgtccggtg tgccgatttc
    20221 caaaatcagg caaaagacgg caaaactgct ttgcaggagg cgttgcaggc acgccgcttt
    20281 gctttgccga aataccgtat cgaagagcaa atcggccatg ccaacgacag tatgtttgtg
    20341 gtttcctgcg atttgggcga actgggtttc gtgtgccgtg ccaaagggac gagccgcaag
    20401 gcggcggaac aggaggcggc gaaagaggct ttgaaatggc tggaagagaa gctgccgctg
    20461 aagaagaaaa agaaatgagg cggcgcgtga atatgccgtc tgaacatatg gatacgaaag
    20521 caaatatgga tattgaaacc ttccttgcag gggaacgcgc cgccggcgga taccgttgcg
    20581 gcttcgtggc gattgtcggc cgtccgaacg tgggcaaatc aacgctgatg aaccatctca
    20641 tcggtcagaa gatcagcatc accagcaaaa aggcgcagac gacgcgcaac cgcgtaacgg
    20701 ggatttatac cgacgatacc gcgcagttcg tgtttgtcga tacgcccggc tttcaaaccg
    20761 accaccgcaa cgcgctcaac gacaggctga atcaaaatgt taccgaggcg ctcggcggcg
    20821 tggatgtggt ggttttcgtc gtggaggcga tgcgctttac cgatgccgac cgcgtcgtgt
    20881 tgaaacaact gcccaagcac acgccggtca ttttagtggt caacaaaatc gacaaggaca
    20941 aggcgaaaga ccgttacgcg ctggaggcgt ttgttgccca agtgcgcgcc gaatttgaat
    21001 ttgcggcggc ggaggcggtc agcgcgaaac acggattgcg gattgccaac ctgttggagc
    21061 tgattaagcc gtatctgccc gaaagcgtgc cgatgtatcc cgaagatatg gttacggaca
    21121 aatcggcgcg ttttttagcg atggaaatcg tgcgtgaaaa actcttccgc tatttgggcg
    21181 aggaattgcc ttatgcgatg aatgtcgaag tggagcagtt tgaagaggaa gacggtttga
    21241 accgcatcta catcgccgtt ttggtcgata aggaaagcca aaaggcgatt ttaatcggca
    21301 aaggcgggga gcgtttgaag aagatttcca ccgaagcgcg gttggatatg gaaaaactgt
    21361 ttgataccaa agtatttttg aaggtctggg tcaaagtcaa atccggttgg gcggacgaca
    21421 tccgcttcct gcgcgagctg ggtttgtagt ttttcttgct gaactttacg caaatgccgt
    21481 ccgaacaggt ttcagacggc attttgtttc aatcgggaat atctttgtta aaaacgggtt
    21541 gatattatct gtgcatatta tagtggatta acaaaaacca gtacggcgtt ggctcgcctt
    21601 agctcaaaga gaacgattct ctaaggtgct gaagcaccaa gtgaatcgat tccgtactat
    21661 ctgtactgtc tgcggctttg ccgccttgtc ctgatttttg ttaatccact ataaagaccg
    21721 tcgggcatct gcagccgtca ttcccgcgca ggcgggaatc tagtccgttc ggtttcggtt
    21781 tttttggcta gtgccgcaac attaaatttc tagattccca ctttcgtggg aatgacgcga
    21841 ttagagtttc aaaatttatt ctaaatagct gaaactcaac gcactggatt cccg
//
LOCUS       DAXISH010000033        21806 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.033, whole genome shotgun sequence.
ACCESSION   DAXISH010000033 DAXISH010000000
VERSION     DAXISH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 21806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21806
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.033"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            127..678
                     /locus_tag="ACFOV4_001222"
     CDS             127..678
                     /locus_tag="ACFOV4_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619235.1"
                     /translation="MKVLNGWSDRKMWRVLSALPIGVVFFDLIYGFVLNVLQGLDLQR
                     AVPDLEGVLAVTPDIAFNSLQIVANGGMAAVVCFGLAVVFLLNRSVRRRQVLEIGVFR
                     MLGLVAVLAFSAPSVWEWANALPLLLKGADVVNTGNARYVLTALCMPFPAVSCVIGLV
                     GRFRLQTASGRAAKSGGAGKADG"
     gene            complement(955..1647)
                     /locus_tag="ACFOV4_001223"
     CDS             complement(955..1647)
                     /locus_tag="ACFOV4_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFC7619236.1"
                     /translation="MFHAFILRIYTMIKNISKLINHAVLIGFIPNIVFAYPIFAENPA
                     SYQNIHVRSWKARRDSGIVKQDLDFSCGAASIATLLNNFYGRHYSEAEILDKMDKTQM
                     RASFDDMQRIMPELGFEAQGYALPFEQLVQLKIPVIVYLKYRKNNHFSVLNGINGETV
                     LLADPSLGHVSMSKSQFLSAWKTRDGEMEGKILAIVPKNTDFVRNQMFFNKNPVRQTR
                     FTVEQIQMRQKR"
     gene            complement(1953..2510)
                     /locus_tag="ACFOV4_001224"
     CDS             complement(1953..2510)
                     /locus_tag="ACFOV4_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619237.1"
                     /translation="MMQKHKCLIDFILTVASQIAYADLPLSLEELLTDKGKFKLESSI
                     SYINTERNQSEFANPIYVQTSATKIATVMAMMITPVMAQNLDSQVFDSQNVKAIQLSQ
                     AEMKETQGEFVPIIAAAAFGGALGAWEYHGANLYNHGKLGTAQGAATAAGIGAATGVA
                     AKQGWLLLPEADWLEIWHGDRVFMH"
     gene            complement(2755..2913)
                     /locus_tag="ACFOV4_001225"
     CDS             complement(2755..2913)
                     /locus_tag="ACFOV4_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619238.1"
                     /translation="MKTPLPICTLSALAACALSGQGGSRVYGEIKARDLCVTAPILLS
                     AFCLACSR"
     gene            complement(2910..3752)
                     /locus_tag="ACFOV4_001226"
     CDS             complement(2910..3752)
                     /locus_tag="ACFOV4_001226"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC7619239.1"
                     /translation="MLVCNPYEVVIHGTTSSGKIFRPSDWAERLCGILSSFTKDNRLS
                     YSKWVRPMLVDNIRCVAVDKKLETDNPQMFRFLMDFAADNDLRVIDCKALLEEREQGG
                     QNNPADEHVMLAQAIEEKHAAEKAQEQTASGASYVLREIGADDTATAFAALSVLRSAL
                     TDINRFTEQINKVQRPQGYRLLGIFEEGKHNAVAVCGFREACTLASGRHIHIDDIVTL
                     PQSRRKGYASRLLEEVRKIGAETGVTKIHLNVHVNHDRADAHRLYFKNGFEICAYHFR
                     CDPK"
     gene            3818..3961
                     /locus_tag="ACFOV4_001227"
     CDS             3818..3961
                     /locus_tag="ACFOV4_001227"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619240.1"
                     /translation="MPSEKYGIRAVKLCGGKCAIIRAVLPLLRSCSANIQAAWTTYNR
                     IPA"
     gene            3991..4911
                     /gene="pyrB"
                     /locus_tag="ACFOV4_001228"
     CDS             3991..4911
                     /gene="pyrB"
                     /locus_tag="ACFOV4_001228"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HFC7619241.1"
                     /translation="MPNPLYRQHIISISDLSREQLECLLQTALKLKAHPRGDLLEGKL
                     IGSCFFEPSTRTRLSFETAVQRLGGKVIGFSDGANTSAKKGETLADTARIISGYTDAI
                     IQRHPKDGAARVAAEFSRVPVINAGDGTNQHPSQTLLDLVTIYETQGRLDKLKIAMAG
                     DLKYGRTVHSLCQALKRWGCEFAFVSPPSLAMPDYITEELDEAGCRYRILGSLEEAAE
                     WADILYMTRVQRERFDEQEFAKIQGKFNLDASMLARAKPNLRVLHPLPRVDEIHPDVD
                     ATPHAYYFEQATNGVYARMAILSLVLNEEV"
     gene            4921..5379
                     /gene="pyrI"
                     /locus_tag="ACFOV4_001229"
     CDS             4921..5379
                     /gene="pyrI"
                     /locus_tag="ACFOV4_001229"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009347 - aspartate carbamoyltransferase
                     complex [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HFC7619242.1"
                     /translation="METPKLSVEAIEKGTVIDHIPAGRGLTILRQFKLLHYGNAVTVG
                     FNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDHFKVVQKRHLNLPDEI
                     AEVFRCPNTNCAGHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA"
     gene            5444..6109
                     /locus_tag="ACFOV4_001230"
     CDS             5444..6109
                     /locus_tag="ACFOV4_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619243.1"
                     /translation="MMMHASVQSRFAPILYVLIFFAGFLTAQIWFNQKAYTEELPPLL
                     SALSAVALVWLAWAFVSARSRAKAEKFYREKMIQNESIHPVLHASLQHLEHKPQMLAL
                     LVKNHGKGMAEQVRFKAEVLPDDEDARTIAAELAKMDMFALGTDAVASGETYGRVFAD
                     IFELSAALEGRAFKGMLKLTAEYKNIFGDACRSETALDLGALNQALQEISKTSEKSKR
                     IFY"
     gene            complement(6172..7389)
                     /locus_tag="ACFOV4_001231"
     CDS             complement(6172..7389)
                     /locus_tag="ACFOV4_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFC7619244.1"
                     /translation="MQRRIITLLCAAGMAFSTQTLAANLEVRPNAPERYTVKQGDTLW
                     GISGKYLYSPWQWGRLWDANRDQIHNPDLIYPDQVLVLRHVDGEPRLGLEQTDGIPVV
                     KMSPDKEVSGYGIPAIDVNFYRIFMRHPQIVSRKETAAAPRLLSGPEGRLLYTKGTRV
                     YTKGLKEPGRYLTYRINKNITDPDTGKFLGQEVAFSGIVRSLDYTDSVLEQRSKQAGE
                     RPKDNEYHTRTHPLITPLRTPSIQPLVVETAISEIQQGDYLMKMPEDTDRFNMMPHEP
                     SRPVQAKIVSVFEGTRIAGQFQTITIDKGEADGLDKGTVLSLYKRKKTMQVDLSNNFK
                     SRDTVELISTPAEEVGLAMVYRTSEHLSSAIILENISDISVGDTAANPGRDLDNIPDQ
                     GRSRVKFGFNRSE"
     gene            7573..8076
                     /gene="def"
                     /locus_tag="ACFOV4_001232"
     CDS             7573..8076
                     /gene="def"
                     /locus_tag="ACFOV4_001232"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFC7619245.1"
                     /translation="MALLNILQYPDERLHTVAKPVEQVDERIRKLIADMFETMYESRG
                     IGLAATQVDVHERVVVMDLTEDRSEPRVFINPVIVEKDGETTYEEGCLSVPGIYDTVT
                     RAERVKVEALNEKGEKFTLEADGLLAICVQHELDHLMGIVFVERLSQLKQGRIKTKLK
                     KRQKHTI"
     gene            8163..9089
                     /gene="fmt"
                     /locus_tag="ACFOV4_001233"
     CDS             8163..9089
                     /gene="fmt"
                     /locus_tag="ACFOV4_001233"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFC7619246.1"
                     /translation="MKVIFAGTPDFAAAALRAVAAAGFEIPLVLTQPDRPKGRGMQLT
                     APPVKQAALELGLRVEQPEKLRNNAEALQMLKEVEADVMVVAAYGLILPQDVLDAPKH
                     GCLNIHASLLPRWRGAAPIQRAIEAGDAETGVCIMQMDAGLDTGDVVSEHRYAIQPTD
                     TANEVHDALMEIGAAAVVADLQQLQSKGRLNAVKQPEEGVTYAQKLRKEEARIDWSES
                     AAVIERKIRAFNPVPAAWVEYQGKPMKIRRADVVAQQGTAGEVLSCSADGLVVACGEN
                     ALKITELQPAGGRRMNIAAFAAGRHIEAGTKL"
     gene            9168..10427
                     /gene="rsmB"
                     /locus_tag="ACFOV4_001234"
     CDS             9168..10427
                     /gene="rsmB"
                     /locus_tag="ACFOV4_001234"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFC7619247.1"
                     /translation="MSMALAQKLAADSIAAVAEGRNLQDVLAQIRTAHPDLTAQENGA
                     LQDIAYGCQRYLGSLKHMLAQMLKKPIDNPQLESLLLAALYQLHYTRNAPHAVVNEAV
                     ESIAKIGRGQYRSFANAVLRRFLRERDKLAASCKKDDVAKHNLPLWWVAYLKNHYPKH
                     WHNITAALQSHPPMTLRVNRRHGNAESYLEKLAAEGIAAKALDEYAVTLEEAVPVNRL
                     PGFSDGIVSVQDFGAQQAAYLLNPKDGERILDACAAPGGKTGHILELADCRVTALDID
                     AGRLKRVEDNIARLGFQTASAACADARDLAAWYDGKPFDAILADVPCTASGVARRNPD
                     VKWLRRPTDALKTARQQEALLDALWQTLKQGGRMLLATCSVFVEENDGQLQKFLNRHA
                     DAEPIESRVLLPNKHQDGFYYALIQKH"
     gene            10393..10992
                     /locus_tag="ACFOV4_001235"
     CDS             10393..10992
                     /locus_tag="ACFOV4_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4390 domain-containing protein"
                     /protein_id="HFC7619248.1"
                     /translation="MAFITRLFKSIKQWLVLLPMLSVLPDAAAEGIDVSRAEARITDG
                     GQLSISSRFQTELPDQLQQALRRGVPLNFTLSWQLSAPIIASYRFKLGQLIGDDDNID
                     YKLSFHPLTNRYRVTVGAFSTDYDTLDAALRATGAVANWKVLNKGALSGAEAGETKAE
                     IRLTLSTSKLPKPFQINALTSQNWHLDSGWKPLNIIGNK"
     gene            10992..13112
                     /locus_tag="ACFOV4_001236"
     CDS             10992..13112
                     /locus_tag="ACFOV4_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFC7619249.1"
                     /translation="MRRFLPIAAICAVVLLYGLTAATGSTSSLADYFWWIVAFSAMLL
                     LVLSAVLARYVILLLKDRRDGVFGSQIAKRLSGMFTLVAVLPSVFLFGVSAQFINGTI
                     NSWFGNDTHEALERSLNLSKSALNLAADNALGNAVPVQIDLIGAASLPGDMGRVLEHY
                     AGSGFAQLALYNAASGKIEKSINPHKLDQPFPGKARWEKIQQAGSVRDLESIGGVLYA
                     QGWLSAGTHNGRDYALFFRQPVPKGVAEDAVLIEKARAKYAELSYSKKGLQTFFLATL
                     LIASLLSIFLALVMALYFARRFVEPVLSLAEGAKAVAQGDFSQTRPVLRNDEFGRLTK
                     LFNHMTEQLSIAKEADERNRRREEAARHYLECVLEGLTTGVVVFDEQGCLKTFNKAAE
                     QILGMPLTPLWGSSRHGWHGVSAQQSLLAEVFAAIGAAAGTDKPVHVKYAAPDDAKIL
                     LGKATVLPEDNGNGVVMVIDDITVLIHAQKEAAWGEVAKRLAHEIRNPLTPIQLSAER
                     LAWKLGGKLDEQDAQILTRSTDTIVKQVAALKEMVEAFRNYARSPSLKLENQDLNALI
                     GDVLALYEAGPCRFAAELAGEPLMVAADTTAMRQVLHNIFKNAAEAAEEADVPEVRVK
                     SEAGQDGRIVLTVCDNGKGFGREMLHNAFEPYVTDKPAGTGLGLPVVKKIIEEHGGRI
                     SLSNQDAGGACVRIILPKTVKTYA"
     gene            13105..14382
                     /locus_tag="ACFOV4_001237"
     CDS             13105..14382
                     /locus_tag="ACFOV4_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HFC7619250.1"
                     /translation="MRSSDILIVDDEIGIRDLLSEILQDEGYSVALAENAEEARKLRH
                     QVRPAMVLLDIWMPDCDGITLLKEWAKNGQLNMPVVMMSGHASIDTAVEATKIGALDF
                     LEKPISLQKLLSAVENALKHGAAKIETGPVFDKLGNSAAIQEMNREVGAAVKCASPVL
                     LTGEAGSPFETVARYFHKNGTPWVSPARVEYLIDMPMELLQKAEGGVLYVGDIAQYSR
                     NIQAGIAFIVGKAERCRVRVVASGSRAAGSDGIACEEKLAELLSESVVRIPPLRMQHE
                     DIPFLIQGIACNVAESQKIAPAAFSEDALAVLTRYDWPGNFDQLQSVVATLLLEADGQ
                     EIGAAAVSSLLGQNVPAEGAEDMVGGFNFNLPLRELREEVERRYFEYHIAQEGQNMSK
                     VAQKVGLERTHLYRKLKQLGIGVSRRAGEKTEE"
     gene            14473..15660
                     /gene="dprA"
                     /locus_tag="ACFOV4_001238"
     CDS             14473..15660
                     /gene="dprA"
                     /locus_tag="ACFOV4_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFC7619251.1"
                     /translation="MTEDERFAWLQLAFTPYIGAESFLLLMRRFGSAQNALSAPAEQV
                     AALIRHKQALEAWRNAEKRALARQAAEAALEWEMRDGCRLMLLQDEDFPEMLTQGLTA
                     PPVLFLRGNVQLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
                     AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFP
                     RRNRLIAALSQVTLVVEAALESGSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIK
                     DGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQTAYAPPPAAKMPSEG
                     AAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQR
                     IRT"
     gene            15686..16147
                     /locus_tag="ACFOV4_001239"
     CDS             15686..16147
                     /locus_tag="ACFOV4_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 family protein"
                     /protein_id="HFC7619252.1"
                     /translation="MTEVIAYLIEHFQDFDTCPPPEDLGMLLEEAGFDTMEIGNTLMM
                     MEVLLNSSEFSAEPADSGALRVYSKEETDNLPQEVMGLMQYLIEEKAVSCEQREIIIH
                     ALMHIPGDEITVDTAKVLTLLLLWANKSELPVLVGDELMSALLLDNKPTMN"
     gene            16219..18525
                     /gene="topA"
                     /locus_tag="ACFOV4_001240"
     CDS             16219..18525
                     /gene="topA"
                     /locus_tag="ACFOV4_001240"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFC7619253.1"
                     /translation="MAKNLLIVESPSKAKTLKKYLGGDFEILASYGHVRDLVPKSGAV
                     DPDNGFAMKYQLISRNGKHVDAIVAGAKEAENIYLATDPDREGEAISWHLLEILKSKR
                     GLKNIKPQRVVFHEITKNAVLDAVAHPREIEMDLVDAQQARRALDYLVGFNLSPLLWK
                     KIRRGLSAGRVQSPALRLICERENEIRAFEAQEYWTVHLDSHKGRSKFTAKLAQYNGA
                     KLEQFDLSNEAAQADVLKELEGKEAVVTAIEKKKRSRNPAAPFTTSTMQQDAVRKLGF
                     TTDRTMRTAQQLYEGIDVGQGAIGLITYMRTDSVNLADEALTEIRHYIENKIGKEYLP
                     SAAKQYKTKSKNAQEAHEAIRPTSVYRTPESVKPFLSADQFKLYQMIWQRTVACQMTP
                     AKFDQTTVDITVGKGVFRVTGQVQTFAGFLSVYEESSDDEEGEDSKKLPEMSEGDKLP
                     VDKLYGEQHFTTPPSRYNEATLVKALEEYGIGRPSTYASIISTLKDREYVTLEQKRFM
                     PTDTGDIVNKFLTEHFAQYVDYHFTAKLEDQLDEIADGKRQWIPLMDKFWKPFIKQVE
                     EKEGIERAKFTTQELDETCPKCGEHKLQIKFGKMGRFVACAGYSECSYTRNVNETAEE
                     AAERIAKAEAEQAELDGRECPKCGGRLVYKYSRTGSKFIGCANYPKCKHVEPLEKPKD
                     TGVQCPQCKKGNLVERKSRYGKLFYSCSTYPDCNYATWNPPVAESCPKCAWPVLTIKT
                     TKRWGVEKVCPQKECGWKEQIEPPAPKE"
     gene            complement(18598..19293)
                     /locus_tag="ACFOV4_001241"
     CDS             complement(18598..19293)
                     /locus_tag="ACFOV4_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619254.1"
                     /translation="MMKDLNLSNSLFKGYNDKHGLMICGYEWGWSKADETAYVAGEYK
                     LPENKIDHTFANKSLYFGEQAKKWRYDNTIKNWFEMWGHPLDENGLGGAFEKSLVQTN
                     WAATQGNTIDNPDKFTQPEHIDNFLYHIEKLRPKVILFMGSRLADFLNNQNVLPRFEQ
                     LVGKQTKPLETVQKEFDGTRFNVKFQSFEDCEVVCFPHPSASRGLSYDYIALFAPEMN
                     RILSDFKTTRGFK"
     gene            complement(19313..19864)
                     /locus_tag="ACFOV4_001242"
     CDS             complement(19313..19864)
                     /locus_tag="ACFOV4_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619255.1"
                     /translation="MEFLSLHPWWSFFIILTIILSYIGFCAHFHIQNGAVFFYSYRDV
                     TIVFLTPVILIALSYLIKNKEILSACILCITLIAFSWAWIIIYRPNTKRFFLSLLIVW
                     GKLLLSTIVWAILAISLGLAVITGNSKRKKYERRDRHAERNEKAFIGALLVGFELSRN
                     LLNLCCLHKDFSTPSKNIEVNRS"
     gene            19983..20360
                     /locus_tag="ACFOV4_001243"
     CDS             19983..20360
                     /locus_tag="ACFOV4_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HFC7619256.1"
                     /translation="METHEKIRLMRELNKWSQEDMAEKLAMSAGGYAKIERGETQLNI
                     PRLEQLAQIFKIDMWDLLKSGGGGMVFQINEGDSGGDIALYASGDVSMKIEFLKMELK
                     HCKEMLEQKDKEIELLRKLTETV"
     gene            20449..21018
                     /gene="rsmD"
                     /locus_tag="ACFOV4_001244"
     CDS             20449..21018
                     /gene="rsmD"
                     /locus_tag="ACFOV4_001244"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFC7619257.1"
                     /translation="MAAGKHTKHSNQVRIIGGQCRGRKLSFASANGLRPTPDSVREKL
                     FNWLGQDLTGKTVLDLFGGSGALGIEAASRNAKRVLISDNNRQTVQTLQKNSRELGLG
                     QVQIVFSDGIAYLKTVSEQFDVVFLDPPFAWQDWQILFDALKPCLNPRAFVYLEAGTL
                     PNIPDWLTEYREGKSGQSTFELRVFQVAE"
     gene            21141..21392
                     /locus_tag="ACFOV4_001245"
     CDS             21141..21392
                     /locus_tag="ACFOV4_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhL family 4Fe-4S dicluster ferredoxin"
                     /protein_id="HFC7619258.1"
                     /translation="MSLFITDECINCDVCEPECPNDAISQGEEIYEINPNLCTQCVGH
                     YDEPQCQQVCPVDCILIDEEHPETHDELMAKYEKIIQFK"
     gene            21489..21572
                     /locus_tag="ACFOV4_001246"
     tRNA            21489..21572
                     /locus_tag="ACFOV4_001246"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21523..21525,aa:Tyr,seq:gta)
     gene            21603..21676
                     /locus_tag="ACFOV4_001247"
     tRNA            21603..21676
                     /locus_tag="ACFOV4_001247"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21635..21637,aa:Gly,seq:tcc)
     gene            21686..21760
                     /locus_tag="ACFOV4_001248"
     tRNA            21686..21760
                     /locus_tag="ACFOV4_001248"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21718..21720,aa:Thr,seq:ggt)
BASE COUNT         5394 a         5461 c         5999 g         4952 t
ORIGIN      
        1 gacgttttaa caacagtgag ataaaagttc ttgttccatt ttaaaacaat tagtaaaatc
       61 aagtttgtcc tagttatcta ggacagcccc ttattttttg ttcggcggct tgcgtggtcg
      121 ggtaaaatga aggttttgaa cggttggtcg gacaggaaga tgtggcgggt tttgagtgct
      181 ttgccgatag gcgtggtgtt ttttgatttg atctacggtt ttgtgttgaa tgtgttgcag
      241 ggtttggatt tgcagcgtgc cgtgccggat ttggaaggcg tgttggcggt tacgcccgat
      301 attgcattca acagtttgca gattgtcgcc aacggcggta tggcggcggt ggtctgtttc
      361 gggttggcgg ttgtgttttt gctcaaccgt tcggtgcggc ggcggcaggt gttggaaatc
      421 ggggtgttcc ggatgttggg gctggtggcg gtattggcgt tcagcgcgcc gtcggtgtgg
      481 gagtgggcga acgcgctacc gctgctgctg aagggcgcgg acgtggtcaa tacggggaat
      541 gcgcgttatg tgctgacggc tttgtgtatg ccctttccgg cggtgtcgtg cgtcatcggg
      601 ctggtggggc ggttcaggct tcagacggca tcgggcaggg cggcaaagtc agggggtgcg
      661 ggcaaggcgg acggatagga cgcatttttc agcgggtgcg tcgagaagca gccgatgtgt
      721 ttggcagccg cagcttgggg gggtgtagtg ctaatggcgg tttctttgct tttatagtgg
      781 attaacaaaa accagtacgg cgttgcctcg ccttagctca aagagaacga ttctctaagg
      841 tgctgaagca ccaagtgaat cggttccgta ctattggtac tgtctgcggc ttcgtcgcct
      901 tgtcctgatt tttgttaatc cactatataa aataaatggg caaaaatcgg tttattatcg
      961 tttttgccgc atttggattt gttctaccgt aaaacgtgtt tgacgaacgg gattcttatt
     1021 aaaaaacatc tgatttctaa caaaatcagt attttttggc acgatggcta aaatttttcc
     1081 ttccatttcg ccatcacgtg ttttccatgc gctcaagaat tgtgatttgc tcattgagac
     1141 gtgccccagc gatggatcag ccagcaaaac agtttctccg ttaataccgt tcaataccga
     1201 aaaatggttg tttttacggt attttaaata cacaattaca ggaattttta gttgtaccaa
     1261 ctgttcaaat ggcaaagcat aaccttgtgc ttcaaaaccc agttcgggca ttatgcgttg
     1321 catatcatca aaagaagcac gcatttgggt tttatccatt ttgtccaaga tttccgcttc
     1381 agaataatgt ctgccataaa aattattcag taacgtggca atcgaagccg cgccgcaaga
     1441 aaaatccaaa tcttgtttta ctatgccgga atctcgccgt gctttccaac tccgtacatg
     1501 gatgttttgg taagaagcgg ggttttcagc aaatataggg taagcaaaaa caatatttgg
     1561 gataaagcca attaaaaccg catggtttat taatttagaa atatttttta tcatagtata
     1621 tatgcgtaga ataaacgcat gaaacataaa aaaataaaat catatgcaat tttattgcat
     1681 gaataaatat gaataaaata gataatgatg ggagtaaata cgccatgtat tttggaagtt
     1741 taaatttatt aataataaaa taatttatcg tagcgcaaat aaatcccaaa attggaacga
     1801 ttagaaaaaa aattaataca cccatcatca tgcaaactct atattaataa atagctaact
     1861 aattctattg tggaaattag ttagctaact aaaagttatt aatgattatt tccgagaatt
     1921 gactgcattg ttggcagcat tggccccaaa acctagtgca tgaatacccg gtctccatgc
     1981 caaatttcca gccaatccgc ctccggcagc agcagccagc cctgttttgc cgctactcct
     2041 gttgccgcac cgattcctgc cgcagtagcc gcgccttgcg cagttcctaa tttaccatga
     2101 ttatacaaat tagcaccatg atactcccat gcacctaatg caccgccaaa agcagcggct
     2161 gcaataatgg gaacaaattc accttgtgtt tctttcattt cagcctgtga taattgaatt
     2221 gctttcacat tttggctgtc aaaaacttgg ctgtctaaat tttgcgccat tacaggtgta
     2281 atcatcatag ccattacagt tgcaattttc gttgcgctgg tttgcacata aataggatta
     2341 gcaaattcgc tttgattgcg ttcagtgttg atgtagctaa tactgctttc tagtttgaat
     2401 ttacccttgt cagtcaataa ttcttccaaa cttaaaggta agtcagcata agcaatttgg
     2461 ctggcaacag tcaaaataaa atctattaga catttgtgtt tttgcatcat ttcgtttgat
     2521 tttctagttt ttgagaatga tacaaagttt ttttacaaag taaagagtca ctctgaaaaa
     2581 cattttttca ttataaatca aaatattgat agaataaata gcgagcatcg attcacggtg
     2641 tactttagtg caaagcgtac aacgcgagcc tgaaccacca gccgcaacag gaaaagaaag
     2701 ccgatagagt gcaatgcttg ccaacgtgca agcgagcttg caagaacgct tggctcaacg
     2761 agagcaggca agacagaaag cagaaagcag gataggagcg gtaacgcaaa ggtctcgggc
     2821 tttgatttcg ccgtaaaccc tgctgccgcc ttgtccggaa agggcgcagg cggcgagtgc
     2881 cgacagggtg cagatgggga ggggggtttt catttggggt cgcaacggaa gtggtatgcg
     2941 cagatttcaa aaccgttttt gaaatacagg cggtgcgcgt cggcacggtc gtggttgacg
     3001 tggacgttga ggtggatttt ggttacccct gtttccgcgc cgattttgcg gacttcttcc
     3061 aaaaggcgcg aggcgtagcc tttgcggcgg ctttgcggca gggtaacgat gtcatcgatg
     3121 tggatgtggc ggccgctggc gagggtgcag gcttcgcgga agccgcagac ggcgacggca
     3181 ttgtgtttgc cttcttcaaa aatacccagc aggcggtagc cttgggggcg ttggactttg
     3241 ttgatctgtt cggtaaagcg gttgatgtcg gtcagggcgg aacgcaaaac gctcaaggct
     3301 gcaaaggcgg tggcggtgtc gtccgcgccg atttcgcgca aaacgtagga tgcgcccgag
     3361 gcggtctgtt cctgtgcttt ctcggcggcg tgtttttctt cgattgcctg tgccagcatg
     3421 acgtgttcgt cggcagggtt gttttgtccg ccctgttcgc gttcttcgag cagggctttg
     3481 cagtcgatga cgcgcaggtc gttgtcggcg gcaaagtcca tcaggaagcg gaacatttgg
     3541 gggttgtcgg tttccagttt tttatcgacg gcgacgcagc ggatgttgtc caccagcatg
     3601 gggcgcaccc atttcgaata ggagaggcgg ttgtctttgg tgaacgagga caggatgccg
     3661 cacaggcgtt ccgcccagtc gctgggacgg aaaatcttgc cggaactcgt tgtgccgtgg
     3721 atgacgactt cgtaggggtt gcagactaac atggcggctt cctgaaaaga aatgtctggc
     3781 gcgattatac cttatgctta tgcgggcgtg tttggatatg ccgtctgaaa agtacgggat
     3841 tcgtgcggta aaactttgcg gcggcaaatg tgcgataata cgcgccgtat tgccgctttt
     3901 gcgaagctgt tccgcaaaca tacaggcggc gtggacgacg tataaccgga tacccgcctg
     3961 acgcgggttt tttacggaag gggggcaaaa atgcctaatc cgctttacag acagcatatc
     4021 atctccattt cggatttgtc gcgcgaacag ttggaatgcc tgcttcagac ggcattgaag
     4081 ctgaaggcgc atccgcgcgg cgatttgttg gaaggcaaac ttatcggttc gtgtttcttt
     4141 gaaccgtcca cgcgcacgag gctgtcgttt gaaacggcgg tgcagcggct gggcggcaag
     4201 gtcatcggct tttcggacgg cgcgaatacc agtgccaaaa aaggcgagac gcttgccgat
     4261 accgcccgca tcatttccgg ctacaccgac gcaatcatcc aacgccaccc caaagacggc
     4321 gcggcgcgcg tggcggcgga gttttcgcgc gtccccgtca tcaacgccgg cgacggcacc
     4381 aaccagcacc ccagccagac cttgttggat ctggtaacga tttatgaaac gcaggggcgt
     4441 ttggacaagc tcaaaatcgc catggcgggc gacttgaaat acgggcgcac cgtgcattcg
     4501 ctttgtcagg cgttgaaacg ctggggctgc gaatttgcct ttgtttcgcc gcccagcctc
     4561 gcgatgcccg actacattac cgaagagttg gacgaagccg gctgccgata ccgtatcctc
     4621 ggtagtttgg aagaagcggc ggaatgggcg gatatcctgt atatgacccg cgtccagcgc
     4681 gaacgtttcg acgaacagga atttgccaaa atccaaggca aattcaatct cgacgcatcc
     4741 atgcttgccc gcgccaaacc gaacctgcgc gtgctgcacc ctttgccgcg cgtggacgaa
     4801 atccatcccg atgtcgatgc tacgccgcat gcctattatt tcgagcaggc gaccaacggc
     4861 gtttatgcgc gtatggcgat attgtcgctg gtgttgaacg aagaagtgtg aggaaccgat
     4921 atggaaaccc cgaaactcag tgtcgaagcc attgaaaaag gtacggttat cgaccatatt
     4981 cccgccggca gggggctgac catcctgcgc cagttcaaac ttttgcacta cggcaacgcg
     5041 gtaaccgtgg gcttcaacct gcccagcaaa acccaaggca gcaaagacat catcaaaatc
     5101 aaaggcgtgt gcttggacga caaagccgcc gaccgcctcg ccctgttcgc ccccgaagcg
     5161 gtggtcaata ccatcgacca tttcaaggtc gtgcagaagc ggcatttgaa cctgcccgat
     5221 gaaattgccg aagtgttccg ttgcccgaac acgaattgcg ccggccacgg cgagccggtc
     5281 aaaagccggt tttatgttaa aaaacacaac gggcagacgc ggctgaaatg ccattactgc
     5341 gaaaaaacct acagccggga ttcggtggcg gaagcctgac ggattccctt aaaccgagcg
     5401 ggcggcattt catctgccgc ttgttttgcc aatctgaaat ggaatgatga tgcacgcttc
     5461 tgtccaaagc cgtttcgcac cgatacttta tgttttgatt ttctttgccg gttttttgac
     5521 cgcgcaaatt tggttcaatc agaaagccta tactgaagag ctgcctccgc ttctgtccgc
     5581 attgtccgcc gtcgcgctgg tgtggctggc gtgggcgttc gtgtcggcgc gttcaagggc
     5641 taaggcggaa aagttctacc gcgaaaaaat gatacagaac gaaagcatac accccgtcct
     5701 gcacgcttct ttgcaacact tggaacacaa gccgcaaatg ctcgccctgc tggtcaaaaa
     5761 ccacggcaaa gggatggcgg aacaggtcag gttcaaggcg gaagtgctgc ccgacgacga
     5821 agacgcgcgc acgattgccg ccgagttggc aaaaatggat atgtttgcat tggggacgga
     5881 cgcggtcgcc tcgggcgaaa cctatggacg cgtgttcgcc gatattttcg agttgtcggc
     5941 ggctttggaa gggcgcgcgt tcaaaggaat gttgaaactg acggcggaat ataaaaacat
     6001 cttcggcgat gcctgccgtt cggaaacggc gttggatttg ggcgcgctca atcaggcgtt
     6061 gcaggagatt tcaaaaacat cggaaaagtc caaacggata ttttattgaa gatggaaaaa
     6121 tgccgtctga aacggaaggt gtttcagacg gcatttttgt cggatgatta attattcgga
     6181 gcggttgaag ccaaacttca cgcggctgcg gccctgatcc ggtatattgt ccaaatcgcg
     6241 tcccggattg gcggcggtgt cgcctacgga aatatcggag atgttttcca aaatgatggc
     6301 ggacgacagg tgttcggagg tgcggtaaac cattgccaag cccacttctt cggcaggagt
     6361 ggaaatcagt tcgacggtat ccctgctttt gaaattgttg gagaggtcga cctgcatcgt
     6421 tttcttgcgt ttgtagaggc tcaaaaccgt gcctttgtcc aaaccgtccg cctcgccttt
     6481 gtcgatggtg atggtttgaa actggccggc aatccttgtg ccttcaaaca cggaaacgat
     6541 tttagcctga accgggcggg acggttcgtg cggcatcatg ttgaagcggt cggtgtcttc
     6601 cggcattttc atcaggtagt cgccctgctg tatttcggaa atggcggttt cgaccaccag
     6661 cggctgtatc gaaggggtgc gcagcggggt aatcaaagga tgggtgcggg tatggtattc
     6721 gttgtctttc ggccgttctc cagcctgttt cgagcgttgt tcgaggacag agtcggtata
     6781 gtcgagggag cgcacgatgc cgctgaatgc gacttcctgc ccgaggaatt tacccgtatc
     6841 cggatcggtg atgtttttat tgattcggta ggtcaggtag cggcccggct ctttcaggcc
     6901 tttggtgtaa accctggtgc ctttggtgta cagcagcctg ccttccgggc ccgagagcag
     6961 gcgcggcgcg gcagcggttt ctttgcggga aacgatttgc gggtgccgca taaagatgcg
     7021 gtagaagttg acatcgatgg cgggaatacc gtatccggac acttccttat ccggactcat
     7081 tttgacgacg gggatgccgt ctgtctgttc caagccgagg cgcggttcgc cgtcaacgtg
     7141 gcgcaacacc aatacctggt ccggataaat caggtcggga ttgtggattt gatcccggtt
     7201 cgcgtcccac aggcggcccc attgccacgg gctgtacagg tatttgcccg aaatgcccca
     7261 cagggtgtcg ccctgtttga ccgtgtagcg ttccggcgcg ttcgggcgca cctccaaatt
     7321 tgccgccaaa gtttgtgttg agaatgccat acctgccgcg cagagcaggg ttataatacg
     7381 acgttgcata accgttcccc ttatctgata aatttcggtt tgtcttgctt gattgggttg
     7441 gaaaaagcgg cggcagcccc tcgggatgtg ccgcgtgata aaaaatgttc cgcattttaa
     7501 catcgaatta tccgcaccat cacggtaatt atgaaaaaca ggcggcgtat ccgccgaagg
     7561 aaagagaaaa ttatggcttt attgaatatc ttgcaatatc ccgacgagcg tctgcacacg
     7621 gtggcaaagc ctgtcgaaca agtcgacgag cgcatccgga agctgattgc cgatatgttt
     7681 gaaacgatgt acgaatcgcg cggcatcggg ctggcggcga cgcaggtcga tgtgcacgag
     7741 cgcgtggtcg tgatggattt gaccgaagac cgcagcgaac cgcgcgtgtt catcaacccc
     7801 gtcatcgttg aaaaagacgg cgaaaccact tacgaagagg gctgcctgtc cgtgccgggc
     7861 atttacgaca ccgtaacccg cgccgaacgc gtcaaggtcg aggctttgaa cgaaaaaggc
     7921 gaaaagttca cgctggaggc ggacggcttg ctggcgattt gcgtgcagca cgagttggat
     7981 cacctgatgg gcatcgtgtt tgtcgaacgc ctgtcgcagc tcaagcaggg gcggattaag
     8041 accaagctga aaaaacgtca gaaacatacg atttgaccct tttgccgtgc cgtctgaacg
     8101 ctgcaaagtt ttcagacggc acggtcttgt ccgacaattt tacgcacacg caggaacacg
     8161 ctatgaaagt catcttcgcc ggcacgcccg attttgccgc cgccgcctta agagccgttg
     8221 ccgccgccgg ttttgaaatt ccgctggtgc tgacccagcc cgaccgtccg aaagggcgcg
     8281 gtatgcaact gactgccccg cccgtcaaac aagccgcgct ggaactcggt ttgcgcgtcg
     8341 aacagcccga aaaactgcgt aacaacgccg aagccctgca aatgctcaaa gaggtcgagg
     8401 cagacgtaat ggtggttgcc gcctacggtt tgattctgcc gcaagacgtg ttggatgcgc
     8461 cgaaacacgg ctgcctcaat atccacgcct cgctgctgcc ccgttggcgc ggcgcggcgc
     8521 cgattcagcg cgcgattgag gccggcgatg ccgaaaccgg cgtgtgcatt atgcagatgg
     8581 atgccggttt ggacaccggt gatgtggtca gcgaacaccg ctacgccatc caaccgaccg
     8641 ataccgccaa cgaagtccac gacgcgctga tggaaatcgg tgcggcggcg gttgttgccg
     8701 atttgcaaca gcttcaaagc aaaggccgtc tgaacgcggt caaacagccc gaagaaggtg
     8761 ttacttacgc gcaaaaattg cgcaaagaag aggcgcgtat cgattggagc gaaagcgcgg
     8821 cggttatcga acgcaaaatc cgcgccttca accccgtgcc tgccgcgtgg gttgagtatc
     8881 agggcaagcc gatgaaaatc cggcgggcgg acgtggtggc gcaacaaggc acggcaggcg
     8941 aagtgttgtc ctgttcggcg gacggtttgg tcgttgcctg cggcgaaaac gcgctgaaga
     9001 ttaccgaatt gcagcctgcc ggcggcaggc gtatgaatat cgcggcgttt gcggcgggac
     9061 ggcatatcga agcagggacg aagctgtaaa tcccttcaga cggcattccg atccgcaaat
     9121 gggaatgccg tctgaagtca tcagttgaag aaagcgaatc acataatatg agtatggcac
     9181 ttgcccaaaa acttgccgcc gacagcattg cggcggttgc cgaaggacgc aaccttcagg
     9241 acgtgttggc gcaaatccgc accgcgcatc ccgaccttac ggcgcaggaa aacggcgcgt
     9301 tgcaggacat cgcctacggc tgccagcgtt atttgggcag tttgaaacat atgctcgcgc
     9361 agatgctgaa aaagccgatt gacaacccgc agctcgaaag cctgcttttg gcggcgttgt
     9421 accaactgca ttacacgcgc aacgcgccgc atgctgtggt caacgaagct gttgaaagca
     9481 tcgccaaaat cggacgcggg cagtaccgtt cgtttgccaa cgcggttttg cgccgttttt
     9541 tgcgcgaacg cgacaagctc gcggcttcct gcaaaaaaga cgatgtggca aaacacaacc
     9601 tgccgctgtg gtgggtggct tacttgaaaa accattatcc gaaacactgg cacaacatca
     9661 ccgccgcgct gcaatcgcat ccgccgatga cgttgcgcgt caaccgccgg cacggcaatg
     9721 ccgaaagcta tttggaaaaa ctggctgcgg aaggtatcgc cgcaaaggcg ttggacgaat
     9781 atgcggttac gttggaagaa gccgtgccgg tgaaccgcct gcccggtttt tcagacggca
     9841 ttgtttcggt acaggacttc ggcgcgcagc aggcggcgta tcttcttaac ccgaaagacg
     9901 gcgaacggat tttggacgcg tgcgccgcgc cgggcggcaa gacggggcat atcttggaac
     9961 tggcggattg ccgcgttacc gccttggaca tcgatgcagg ccgtctgaag cgtgtggagg
    10021 acaatatcgc gcgcctgggc tttcagacgg catcggcggc gtgtgccgat gcgcgggatt
    10081 tggcggcgtg gtatgatgga aagcctttcg acgcaatcct tgccgacgtg ccatgcaccg
    10141 cttccggcgt ggcgcggcgc aatcccgacg tgaaatggct gcgccgtccg accgacgcgc
    10201 tcaaaaccgc ccgccagcag gaagccctgc tggacgcact ttggcagacg ctgaaacagg
    10261 gcggcagaat gctgcttgcc acctgttccg tgttcgtcga agaaaacgac gggcaattgc
    10321 aaaaattcct caaccgccat gccgatgccg aaccgatcga atcgcgggtg cttttaccga
    10381 acaaacacca agatggcttt tattacgcgc ttattcaaaa gcattaaaca atggcttgtg
    10441 ctgctgccga tgctttccgt tttgccggac gcggcggcgg aggggataga tgtgagccgc
    10501 gccgaagcga ggataaccga cggcgggcag ctttccatca gcagccgctt ccaaaccgag
    10561 ctgcccgacc agctccaaca ggcgttgcgc cggggcgtgc cgctcaactt taccttaagc
    10621 tggcagcttt ccgccccgat aatcgcttct tatcggttta aattggggca actgattggc
    10681 gatgacgaca atattgacta caaactgagt ttccatccgc tgaccaaccg ctaccgcgtt
    10741 accgtcggcg cgttttcgac agactacgac accttggatg cggcattgcg cgcgaccggc
    10801 gcggttgcca actggaaagt cctgaacaaa ggcgcgctgt ccggcgcgga agcaggggaa
    10861 accaaggcgg aaatccgcct gacgctgtcc acttcaaaac tgcccaagcc ttttcaaatc
    10921 aatgcattga cttctcaaaa ctggcatttg gattcgggtt ggaaacctct aaacatcatc
    10981 gggaacaaat aatgcgccgt tttctaccga tcgcagccat atgcgccgtc gtcctgttgt
    11041 acggactgac ggcggcaacc ggcagcacca gttcgctggc ggattatttc tggtggattg
    11101 ttgcgttcag cgcaatgctg ctgctggtgt tgtccgccgt tttggcacgt tatgtcatat
    11161 tgctgttgaa agacaggcgc gacggcgtat tcggttcgca gattgccaaa cgcctttctg
    11221 ggatgtttac gctggttgcc gtactgccca gcgtgtttct gttcggcgtt tccgcacagt
    11281 ttatcaacgg tacgattaat tcgtggttcg gcaacgatac ccacgaggcg cttgaacgca
    11341 gcctcaattt gagcaagtcc gcattgaatt tggcggcaga caacgccctc ggcaacgccg
    11401 tccccgtgca gatagacctc atcggcgcgg cttccctgcc cggggatatg ggcagggtgc
    11461 tggaacatta cgccggcagc ggttttgccc agcttgccct gtacaatgcc gcaagcggca
    11521 aaatcgaaaa aagcatcaac ccgcacaagc tcgatcagcc gtttccaggt aaggcgcgtt
    11581 gggaaaaaat ccaacaggcg ggttcggtca gggatttgga aagcataggc ggcgtattgt
    11641 acgcgcaggg ctggctgtcg gcgggtacgc acaacgggcg cgattacgcc ttgtttttcc
    11701 gtcagccggt tcccaaaggc gtggcagagg atgccgtctt aatcgaaaag gcaagggcga
    11761 aatatgctga gttgagttac agcaaaaaag gtttgcagac ctttttcctg gcaaccctgc
    11821 tgattgcctc gctgctgtcg atttttcttg cactggtcat ggcactgtat ttcgcccgcc
    11881 gtttcgtcga acccgtccta tcgcttgccg agggggcgaa ggcggtggcg caaggcgatt
    11941 tcagccaaac ccgtcctgtt ttacgcaatg acgagttcgg gcgtttgacc aagttgttca
    12001 accacatgac cgagcagctt tccatcgcca aagaagcaga cgagcgcaac cgccggcgcg
    12061 aggaagccgc cagacattat cttgaatgcg tgttggaggg gctgaccacg ggcgtggtgg
    12121 tgtttgacga acaaggctgt ctgaaaacct tcaacaaagc ggcggaacag attttgggga
    12181 tgccgcttac ccccctgtgg ggcagcagcc ggcacggttg gcacggcgtt tcggcgcagc
    12241 agtccctgct tgccgaagtg tttgccgcca tcggcgcagc ggcaggtacg gacaaaccgg
    12301 tccatgtgaa atatgccgcg ccggacgatg ccaaaatcct gctgggcaag gcaaccgtcc
    12361 tgcccgaaga caacggcaac ggcgtggtaa tggtgattga cgacatcacc gttttgatac
    12421 acgcgcaaaa agaagccgcg tggggcgaag tggcaaaacg gctggcacac gaaatccgca
    12481 atccgctcac gcccatccag ctttccgccg aacgtctggc gtggaaattg ggcgggaagc
    12541 tggatgagca ggatgcacaa atcctgacgc gttcgaccga caccatcgtc aaacaggtgg
    12601 cggcattgaa ggaaatggtc gaagcattcc gcaattatgc gcgttcccct tcgctcaaat
    12661 tggaaaatca ggatttgaac gccttaatcg gcgatgtgtt ggcattgtat gaagccggtc
    12721 cgtgccggtt tgcggcggag cttgccggcg aaccgctgat ggtggcggcg gatacgaccg
    12781 ccatgcggca ggtgctgcac aatattttca aaaatgccgc cgaagcggcg gaagaagccg
    12841 atgtacccga agtcagggta aaatcggaag cggggcagga cggtcggatt gtcctgacgg
    12901 tttgcgacaa cggcaaaggg ttcggcaggg aaatgctgca caacgccttc gagccgtatg
    12961 taacggacaa accggcggga acgggattgg gtctgcctgt ggtgaaaaaa atcattgaag
    13021 aacacggcgg ccgcatcagc ctgagcaatc aggatgcggg tggggcgtgt gtcagaatca
    13081 tcttgccaaa aacggtaaaa acttatgcgt agcagcgata ttttaattgt agacgacgaa
    13141 atcggcatcc gcgacctgct gtcggaaatc ctgcaggacg aaggttattc ggtcgcattg
    13201 gcggaaaacg ccgaagaggc gcgcaagctg cgccatcagg tacgcccggc gatggtgttg
    13261 ctggatattt ggatgcccga ttgcgacggc atcacccttt tgaaggagtg ggcgaaaaac
    13321 gggcagctca atatgccggt ggtgatgatg agcgggcatg ccagcatcga taccgccgta
    13381 gaagcgacca aaatcggcgc gctcgacttt ttggaaaaac cgatttccct gcaaaagctg
    13441 ctgtctgccg tcgaaaacgc gttgaaacac ggtgcggcga aaatcgaaac ggggcctgta
    13501 ttcgacaagc tgggcaacag tgcggcgatt caggaaatga accgtgaggt aggggctgcg
    13561 gtgaaatgtg cctctcccgt acttttgacg ggcgaggcag gttcgccgtt tgaaacggtg
    13621 gcacgctatt tccataaaaa cggtacgccg tgggtcagcc cggcaagggt cgaatatctg
    13681 atcgatatgc cgatggaact gttgcagaag gcggagggcg gcgttttgta tgtcggcgac
    13741 atagcccaat acagccgcaa catccaagcc ggcattgcct ttattgtcgg caaggcagaa
    13801 cgctgccgcg tcagggtggt cgcatcgggc agcagggcgg caggttcaga cggcattgcc
    13861 tgcgaggaaa agctggcgga actgctgtcg gaatcggtcg tccgtattcc gccgctgcgt
    13921 atgcagcatg aagatattcc cttcctgata caggggattg cctgcaatgt ggcggaaagc
    13981 caaaagattg cgcccgccgc attcagtgaa gatgcgcttg ccgtgctgac ccgttacgac
    14041 tggccgggaa atttcgacca actgcaaagc gtcgttgcaa cgctgttgtt ggaggcggac
    14101 ggacaggaaa tcggcgcggc ggcggtttct tcccttttgg ggcagaatgt gcctgccgag
    14161 ggagcagaag atatggtggg cgggtttaat ttcaacctgc ccctgcgcga attgagggag
    14221 gaggtggagc ggcgttattt cgagtaccac atcgcccaag aaggtcagaa tatgagcaaa
    14281 gtggcgcaga aagtcggttt ggaacgcacg cacctttacc gcaaactcaa acagctcggc
    14341 atcggcgttt cgcgccgggc gggggaaaaa accgaagaat aggcccggac ggccggtttt
    14401 ccggctgcgg gcttttgttt tcagacggca tttggtgcaa atgccgtctg aaatcgtaag
    14461 gggacggatt ttatgacaga ggacgaacgt ttcgcgtggc tgcaattggc gtttacgccc
    14521 tatatcggcg cggaaagttt cctgctgctg atgcgccgtt tcggcagcgc gcaaaatgcc
    14581 ctgtccgcac cggcggaaca ggtggcggca ctgatacggc acaaacaggc gcttgaggct
    14641 tggcgcaatg cggaaaaacg cgctctggcg cggcaggcgg cagaagcggc attggaatgg
    14701 gaaatgcggg acggatgccg tctgatgctg cttcaggatg aagattttcc cgaaatgctg
    14761 acgcaggggc tgaccgcgcc accggttttg tttttgcgcg gcaacgtaca actgctgcac
    14821 aaaccttccg ccgccattgt cggcagccgt catgccacgc cgcaggcaat gcggattgcc
    14881 aaagatttcg gcaagtcgtt gggcgggcaa aatatccccg ttgtgtcggg tatggcttcc
    14941 ggtatcgata ctgccgccca tcagggcgca ctggaggcag aaggcggcac catcgccgtg
    15001 tgggggacgg gtatagaccg catttacccg ccgtccaata aaaaccttgc ctatgaaatc
    15061 gccgaaaaag gattgattgt cagcgagttt cccatcggta cgcgcccgta tgccggcaat
    15121 tttccgcgcc gcaaccgcct gattgctgcc ctgtcgcaag taacgctggt ggttgaagcc
    15181 gccttggaat ccggttcgct gattaccgcc ggcttggcgg cagaaatggg gcgcgaagtg
    15241 atggcggtac ccggttcgat agacaatccg cacagcaaag gctgccacaa actgattaaa
    15301 gacggcgcaa aattggtgga atgcctggac gacatcctga acgaatgccc ggggctattg
    15361 caaaatacgg gtgcttcatc atattctata aataaggata cgcccgacac gggccgccgc
    15421 gccgttcaga cggcatacgc cccgccgcct gccgcaaaaa tgccgtctga aggggcggca
    15481 ggcggcacag ccgtcggcgg catactggat aaaatgggtt tcgaccccat ccatcccgac
    15541 gtgcttgccg gacagttggc tatgcctgcc gcagatttgt atgccgcact gttggaattg
    15601 gaattggacg gcagcgttgc cgcaatgccc ggcggcagat accagcgtat ccgaacttga
    15661 acgcacttta tattaaggaa cacgaatgac cgaagtcatc gcctacctca tcgaacattt
    15721 ccaagatttc gatacctgtc cgccgcccga agacttgggt atgctgcttg aagaagcggg
    15781 tttcgatacg atggaaatcg gcaacaccct gatgatgatg gaagtattgc tcaacagctc
    15841 cgaattttcc gccgaacctg ccgacagcgg cgcattgcgc gtgtacagca aagaagaaac
    15901 cgacaacctg ccgcaggaag tgatggggct gatgcagtat ctgattgaag aaaaagccgt
    15961 cagctgcgaa cagcgggaaa tcatcatcca cgcgctgatg cacatccccg gcgacgaaat
    16021 taccgtagat accgccaaag tgctgaccct gctgctttta tgggcaaaca agagcgagct
    16081 gcccgtgttg gtcggcgacg agctgatgag cgcgctttta ctcgacaaca aacccacgat
    16141 gaactgaagc ggcttcagac ggcccgcccg aggccgtctg aaacgccggc atcaaaacca
    16201 ccatccagag aacgacaaat ggcgaaaaac ctattaatcg tcgaatcccc gtccaaagcc
    16261 aaaaccctga aaaaatattt gggcggcgat tttgaaatcc ttgcatccta cggacacgtc
    16321 cgcgacctcg tccccaaaag cggcgcggtc gatcccgaca acggctttgc gatgaaatac
    16381 caactcatca gccgcaacgg caaacacgtc gatgccatcg tcgccggtgc caaagaagct
    16441 gaaaacatct acctcgccac cgacccggat agggaaggcg aagccatttc ctggcatctt
    16501 ttggaaatcc tcaaatccaa acgcggcttg aaaaacatca agccgcagcg tgtcgtgttc
    16561 cacgaaatca ccaaaaacgc cgtgctcgat gccgttgccc atccgcgcga aatcgaaatg
    16621 gacttggtcg atgcacaaca agcccgccgt gctttggact atttggtcgg ctttaacctt
    16681 tcgccattgt tatggaaaaa aatccgccga ggtttgagcg cggggcgtgt gcaaagccct
    16741 gctttgcgcc tgatttgtga gcgcgaaaac gaaatccgcg cgtttgaagc gcaggaatat
    16801 tggacggtgc atctcgacag ccacaaaggc cgcagcaagt tcaccgccaa actcgcccaa
    16861 tacaacggcg cgaaactcga acaattcgac ctgtcgaacg aagccgcgca agccgacgta
    16921 ttgaaagaac tcgaaggcaa agaagccgtc gttaccgcca ttgaaaagaa aaagcgcagc
    16981 cgcaatcctg ccgcgccgtt caccacttct accatgcagc aggatgccgt gcgcaaactc
    17041 ggcttcacca ccgaccgcac catgcgtacc gcccaacagc tttatgaagg tatagacgta
    17101 gggcagggcg cgatcggtct gattacctat atgcgtaccg acagcgtgaa tttggcggat
    17161 gaagcgttaa ccgaaatccg ccattacatt gaaaacaaaa tcggcaaaga atatctgccg
    17221 agtgccgcca aacaatacaa aaccaaatcc aaaaacgccc aagaagccca cgaagccatc
    17281 cgtccgactt ccgtgtaccg cacgcccgaa agcgtcaaac ccttcctgag cgcagaccag
    17341 ttcaaactct atcaaatgat ttggcagcgt accgtcgcct gtcagatgac gcctgccaaa
    17401 ttcgaccaaa ccaccgtcga tattaccgtc ggcaaaggcg tattccgcgt aaccggacaa
    17461 gtgcaaacct tcgcaggctt cttgagcgtt tatgaagaaa gcagcgacga tgaagaaggc
    17521 gaagacagca aaaaactgcc cgaaatgagc gaaggcgata aattgcccgt ggacaaactc
    17581 tacggcgaac aacactttac cactccgccg tcgcgctaca acgaagccac gctggttaaa
    17641 gccctcgaag aatacggcat cggccgcccc tcgacctacg ccagcatcat ctccacgctc
    17701 aaagaccgcg aatacgttac ccttgagcaa aaacgcttca tgcccaccga cacaggcgac
    17761 atcgtcaaca aattcctgac cgaacacttc gcccaatacg tcgattacca cttcaccgcc
    17821 aaactcgaag accagcttga cgaaattgcc gacggcaaac gccaatggat tcccttgatg
    17881 gacaaattct ggaaaccgtt catcaaacaa gtggaagaaa aagaaggcat cgaacgcgcc
    17941 aaatttacca cgcaggaact tgatgaaacc tgcccgaaat gcggcgaaca caaactgcaa
    18001 atcaaattcg gcaaaatggg tcgttttgtt gcgtgtgccg gttattccga gtgcagctac
    18061 acgcgcaatg tcaacgaaac cgccgaagag gccgccgagc gcatcgccaa agccgaagcc
    18121 gaacaggccg aactcgacgg acgcgaatgt cctaaatgtg gtggtcgcct agtgtacaaa
    18181 tacagccgaa ccggcagcaa attcatcggc tgcgccaact atccgaaatg caaacacgtc
    18241 gagccgctgg aaaaaccgaa agataccggc gtccagtgtc cgcaatgcaa aaaaggcaac
    18301 ctcgtcgagc gcaaatcccg ctacggcaaa ctgttttaca gttgcagcac ctatcccgac
    18361 tgtaactacg ccacatggaa cccacccgtt gcagaaagct gtccaaaatg cgcatggccg
    18421 gttttaacca tcaaaaccac caaacgctgg ggcgtcgaaa aagtctgccc gcaaaaagaa
    18481 tgcggctgga aagaacagat tgaaccgcct gcgccgaaag agtgagatta ggttggtttg
    18541 aaagagaaaa ggtcgtctga aaaattttca gacgaccttt gcttttctgt gattggttta
    18601 tttgaatccg cgtgttgttt taaagtccga taaaatccgg ttcatttcag gcgcaaacaa
    18661 ggcgatgtaa tcgtaagata gaccgcgact ggcactggga tggggaaagc agacgacttc
    18721 gcaatcttca aacgattgga atttgacatt gaaacgtgta ccgtcaaatt ctttttgcac
    18781 cgtctccagc ggtttggtct gcttaccgac caactgctcg aagcgtggca gtacattttg
    18841 gttgttcaga aaatccgcca acctgctgcc catgaagagg atgactttcg gacgcagttt
    18901 ttcgatgtgg tagagaaaat tatcgatgtg ctcgggttgt gtgaacttgt cgggattgtc
    18961 gatagtgttg ccctgtgtag cagcccagtt ggtttgaacc agggattttt caaatgcacc
    19021 gcccaatcca ttttcgtcta aggggtgtcc ccacatttca aaccaatttt ttatcgtatt
    19081 gtcgtaacgc cacttttttg cctgctctcc gaaatagagg gatttgtttg caaatgtatg
    19141 gtcgattttg ttttcaggga gtttgtattc acctgctaca taagcagtct catcggcttt
    19201 actccaaccc cattcatagc cacaaatcat taagccatgt ttgtcgttgt agcctttgaa
    19261 caggctgttg ctcaaattca aatccttcat catgaactct tccttttaaa atttaagagc
    19321 gattgacttc aatgttttta gatggggtgg aaaaatcctt gtgtaggcaa cataaattca
    19381 ataaatttct tgataattcg aaacctacta atagcgcacc tataaaagct ttttcattac
    19441 gttcagcatg acggtcacgt cgttcatatt ttttacgctt gctgttccct gttattacag
    19501 ctaagccaag tgatatggcg agaattgccc aaacaatagt acttaataac aattttcccc
    19561 atactatcaa tagggaaaga aaaaaccttt tagtattagg tcgatagatt ataatccatg
    19621 cccatgaaaa tgcaataaga gttatacata agatacaagc tgataggatt tctttatttt
    19681 taattaaata acttagggcg atgaggatga caggtgtcaa gaaaacaata gttacatccc
    19741 gatagctata aaagaaaact gccccatttt gaatgtggaa atgtgcacag aatccaatat
    19801 agctaaggat aatagttaat ataataaaaa aagaccacca agggtgaaga gataggaatt
    19861 ccatgttttc cctttttttg taaaaaggaa aaaatcttat ctaatagtta attgcctaac
    19921 cagccagaag aagtttaaaa tctatcccaa taattcaacc atctatacag aaagttcagc
    19981 tcatggaaac ccacgaaaaa atccgcctga tgcgcgaatt gaacaaatgg tcgcaggagg
    20041 atatggcgga aaagctggcg atgtcggcag gcgggtatgc caaaatcgaa cggggcgaaa
    20101 cgcagttgaa tatcccgcgt ttggagcagt tggctcagat tttcaaaatc gatatgtggg
    20161 acttgctcaa atcgggcggc ggcgggatgg tgtttcagat taatgaaggt gatagtggtg
    20221 gcgatattgc gttgtatgcg tcaggtgatg tttcgatgaa aatagaattt ttaaaaatgg
    20281 agttgaaaca ttgtaaagaa atgttggaac aaaaagacaa agaaatcgag ttgctccgca
    20341 agctgaccga aaccgtttaa acagatatgc cgtctgaaaa aagttttcag acggcatatt
    20401 ctttgacagg tcttgtataa taccgtttga acttacaggt ttttgattat ggcggcaggc
    20461 aaacatacca aacacagcaa ccaggtacgc attatcggcg ggcaatgtcg gggcaggaaa
    20521 ttgagttttg catccgccaa cggactgcgt ccaacccccg atagcgtgcg tgaaaagctg
    20581 tttaactggc tgggacagga tttgacgggt aaaacggttt tggatctctt cggaggcagc
    20641 ggcgcactcg gtatagaagc cgcttcgcgc aacgccaaac gcgtgctgat ttcggataac
    20701 aaccgccaaa ccgtgcagac cttgcagaaa aacagtcgcg aactgggttt ggggcaggtg
    20761 caaatcgtct tttcagacgg catcgcatat ttgaagaccg tatccgaaca gtttgatgtt
    20821 gtctttctcg acccgccgtt tgcatggcag gactggcaaa tcctgttcga tgccttgaag
    20881 ccgtgcctga acccccgggc attcgtctat ctcgaggcgg gtacgctgcc gaatattccc
    20941 gattggctga cggaatatag agaagggaaa tcggggcaga gtacattcga attaagggtt
    21001 ttccaagtgg ctgaataata tgcgctttga taatcatttc cgagttgtaa acattcgttt
    21061 gcaaccgtcc ggttcaaaaa aaccttgtgc tataatccgc gcccgcccgg ttttgataat
    21121 ttagtggaaa aggaaaagaa atgtcgcttt ttattaccga cgagtgcatc aactgcgacg
    21181 tatgcgaacc cgaatgcccc aatgatgcca tttcccaagg cgaggaaatt tacgaaatca
    21241 accccaacct ctgcacgcag tgcgtcggac actacgatga gccgcagtgc cagcaggttt
    21301 gcccggtgga ctgcatcctg attgacgaag aacatcccga aacccatgac gagttgatgg
    21361 cgaaatacga aaagattatc cagtttaaat aaattctttt taaaacatca aattatgtct
    21421 gttttgaaat aaaatcaaaa aaaaacttga cggaaaagca agccgctaat aaactaacgt
    21481 tctcttttgg agggattccc gagcggtcaa agggggcaga ctgtaaatct gttgcgaaag
    21541 cttcgaaggt tcgaatcctt ctccctccac caaaattctt acttggggca gtagcgagta
    21601 atgcgggtgt agctcaatgg tagagcagaa gccttccaag cttacggtga gggttcgatt
    21661 cccttcaccc gctccaaaca attaggccca tgtagctcag gggtagagca ctcccttggt
    21721 aagggagagg tcggcagttc aaatctgccc atgggcacca tccctcgatt attcatttct
    21781 ttaaggctta gatatatagg atattg
//
LOCUS       DAXISH010000034        21480 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.034, whole genome shotgun sequence.
ACCESSION   DAXISH010000034 DAXISH010000000
VERSION     DAXISH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 21480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21480
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.034"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            46..204
                     /locus_tag="ACFOV4_001249"
     CDS             46..204
                     /locus_tag="ACFOV4_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619259.1"
                     /translation="MPSEHAFGRRFYNKNTSWRLVLCLSKFLCRAYLRISDGIGLCCL
                     KSVFRFSL"
     gene            286..1407
                     /gene="dnaJ"
                     /locus_tag="ACFOV4_001250"
     CDS             286..1407
                     /gene="dnaJ"
                     /locus_tag="ACFOV4_001250"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFC7619260.1"
                     /translation="MSNQDFYATLGVARTATDDEIKKAYRKLAMKYHPDRNPDNKEAE
                     EKFKEVQKAYETLSDKEKRAMYDQYGHAAFEGGGQGGFGGFGGFGGAQGFDFGDIFSQ
                     MFGGGSGRAQPDYQGEDVQVGIEITLEEAAKGVKKRINIPTYEACDVCNGSGAKPGTS
                     PETCPTCKGSGTVHIQQAIFRMQQTCPTCHGAGKHIKEPCVKCRGAGRNKAVKTVEVN
                     IPAGIDDGQRIRLSGEGGPGMHGAPAGDLYVTVRIRAHKIFQRDGLDLHCELPISFAT
                     AALGGELEVPTLDGKVKLTVPKETQTGRRMRVKGKGVKSLRSSATGDLYCHIVVETPV
                     NLTDRQKELLEEFERISTGLENQTPRKKSFLDKLRDLFD"
     gene            1603..3621
                     /locus_tag="ACFOV4_001251"
     CDS             1603..3621
                     /locus_tag="ACFOV4_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OPT family oligopeptide transporter"
                     /protein_id="HFC7619261.1"
                     /translation="MNKSLSSSVEEYRELTLRGMILGALITVIFTASNVYLGLKVGLT
                     FASSIPAAVISMAVLKFFKGSNILENNMVQTQASAAGTLSTIIFVLPGLLMAGYWSGF
                     PFWQTTLLCIAGGILGVIFTIPLRYAMVVKSDLPYPEGVAAAEILKVGGHEEGDNRQG
                     GSGIKELAAGGALAGLMSFCAGGLRVIADSASYWFKSGTAIFQLPMGFSLALLGAGYL
                     VGLTGGIAILLGISIAWGIAVPYFSSHIPQPSDMEMAAFAMKLWKEKVRFIGAGTIGI
                     AAVWTLLMLLKPMVEGMKMSFKSFGGGAPAAERAEQDLSPKAMIFWVLAMMFVLGVSF
                     YHFIGDSHITGGMAWLLVVVCTLLASVIGFLVAAACGYMAGLVGSSSSPISGVGIVSV
                     VVISLVLLLVGESGGLLADEANRKFLLALTLFCGSAVICVASISNDNLQDLKTGYLLK
                     ATPWRQQVALIIGCIVGALVISPVLELLYEAYGFTGAMPREGMDAAQALAAPQATLMT
                     TIASGIFAHNLEWVYIFTGIAIGAVLIVVDLVLKKSSGGKLALPVLAVGMGIYLPPSV
                     NMPIVAGAVLAAVLKHIIGKKAENREGRLKNAERIGTLFSAGLIVGESLIGVIMAFII
                     AFSVTNGGSDAPLALNLQNWDAAASWLGLAFFVTGMFFFAQRVLKAGK"
     gene            complement(3751..4236)
                     /gene="rfbC"
                     /locus_tag="ACFOV4_001252"
                     /pseudo
     CDS             complement(3751..4236)
                     /gene="rfbC"
                     /locus_tag="ACFOV4_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201170.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
     gene            complement(4275..5141)
                     /gene="rfbA"
                     /locus_tag="ACFOV4_001253"
     CDS             complement(4275..5141)
                     /gene="rfbA"
                     /locus_tag="ACFOV4_001253"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFC7619262.1"
                     /translation="MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLA
                     GIRDILVITAPEDNASFKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNV
                     CLVLGDNIFYGQSFTQTLKQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVSIEEK
                     PQRPKSDWAVTGLYFYDNRAVEFAKQLKPSARGELEISDLNQMYLEDGSLSVQILGRG
                     FAWLDTGTHESLHEAASFVQTVQNIQNLHIACLEEIAWRNGWLSDEKLEELARPMAKN
                     QYGQYLLRLLKK"
     gene            complement(5204..6286)
                     /gene="rfbB"
                     /locus_tag="ACFOV4_001254"
     CDS             complement(5204..6286)
                     /gene="rfbB"
                     /locus_tag="ACFOV4_001254"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFC7619263.1"
                     /translation="MQTANKKTILVTGGAGFIGSAVVRHIIRNTQDSVVNLDKLTYAG
                     NLESLTDIADNPRYAFEQVDICDRAELDRVFAQHRPDAVMHLAAESHVDRSIGSAGEF
                     IQTNIVGTFNLLEAARAYRQQMPSEKHEAFRFHHISTDEVYGDLSGTDDLFTETAPYA
                     PSSPYSASKASSDHLVRAWLRTYGLPTIVTNCSNNYGPYHFPEKLIPLMILNALDGKP
                     LPVYGDGMQIRDWLFVEDHARALYQVVTEGVVGETYNIGGHNEKANIEVVKTICALLE
                     ELAPEKPAGVARYEDLITFVQDRPGHDVRYAVDAAKIRRDLGWLPLETFESGLRKTVQ
                     WYLDNKTWWQNVLNGSYRLERLGTGK"
     gene            complement(6287..6907)
                     /gene="galE"
                     /locus_tag="ACFOV4_001255"
                     /pseudo
     CDS             complement(6287..6907)
                     /gene="galE"
                     /locus_tag="ACFOV4_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248656.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
     gene            complement(6986..7330)
                     /locus_tag="ACFOV4_001256"
     CDS             complement(6986..7330)
                     /locus_tag="ACFOV4_001256"
                     /inference="COORDINATES: protein motif:HMM:NF014177.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HFC7619264.1"
                     /translation="MNKQYPKINYIGNKEKIASWICDQLPSDVDTVADVFSGGCSFAY
                     EAKKRGYRVITNDILAINYQIALALIENNHETLNDDDGAMIFSGSPHAGFMSQRYAEK
                     FYFHDEYQQLDL"
     gene            complement(7323..7517)
                     /locus_tag="ACFOV4_001257"
     CDS             complement(7323..7517)
                     /locus_tag="ACFOV4_001257"
                     /inference="COORDINATES: protein motif:HMM:NF012372.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFC7619265.1"
                     /translation="MRKVFHYEQNRALTVRELAALQSFPDNFIFCGSKIAQQQQVGNA
                     VPPLLAKAIAESILKMSENE"
     gene            complement(7495..8325)
                     /locus_tag="ACFOV4_001258"
     CDS             complement(7495..8325)
                     /locus_tag="ACFOV4_001258"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFC7619266.1"
                     /translation="MHTPLTYIDLFSGAGGLSLGFEQAGFQQLLSVEMESDYCQTYRT
                     NFPHHQLLQKDLTTLTEQDLINCLNGQAVDLIIGGPPCQGFSMAGKIGRTFTDDPRNH
                     LFKEFVRIVKIVQPYFFVMENVARLYTHNSGKTRIEIIQAFQNIGYSVECKILSAADF
                     GVPQIRSRVIFIGRRDKGKISFPEPLQISHQTVGSAIGHFPKLAAGESNPHVANHEAM
                     NHSAQMLEKMAFVKNGGNRNDIPEPLRPKTGDIRKYIRYNSNKTSRLYYRRYAQSFSL
                     "
     gene            complement(8356..10629)
                     /locus_tag="ACFOV4_001259"
     CDS             complement(8356..10629)
                     /locus_tag="ACFOV4_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFC7619267.1"
                     /translation="MNITQILSQELSATTAQINAAIELLDDGATVPFIARYRKEATGG
                     LDDTQLRRLAERLQYLRELEERKAVVLKSIEEQGKLSDDLRAQIEAADNKTALEDLYL
                     PYKPKRRTKAQIAREHGLQPLADVLLAEQSQDVEAAAQGYLNENVPDAKAALDGARAI
                     LMEQFAEDAELIGTLRDKLWNEAEIHAQVVGGKETEGEKFSDYFDHREPVRTMPGHRA
                     LAVLRGRNEGVLNIALKYRPDDTPITQQSEYEQIIARRFKVSDGHKWLRDTVRLTWRA
                     KIFLSLELEALNRLKEAADTDAITVFARNLKDLLLAAPAGRLTTLGLDPGYKNGVKCA
                     VVDDTGKLLDTVIVYLHQENNMLATLSRLIKQHGVKLIAIGNGTASRETDKIAGELVR
                     EMSKMGLHKIVVSEAGASIYSASELAAREFPDLDVSLRGAVSIARRLQDPLAELVKID
                     PKSIGVGQYQHDVNQSQLAKSLDAVVEDCVNAVGVDVNTASAPLLARISGLNQTLAQN
                     IVAYRDENGAFDSRKKLLKVPRLGEKTFEQAAGFLRINGGKEPLDASAVHPEAYPVVA
                     KMLAQQGISAAELIGNRERVKQIKASDFTDERFGLPTILDILSELEKPGRDPRGEFQT
                     ASFAEGIHEISDLQVGMILEGVVSNVANFGAFVDIGVHQDGLVHISALSNKFVQDPRE
                     VVKAGDVVKVKVLEVDAARKRIALTMRLDDEPGGAKHKMPSENRSRERTAGRKPQRND
                     RAPANSAMADAFAKLKR"
     gene            complement(10694..11344)
                     /locus_tag="ACFOV4_001260"
     CDS             complement(10694..11344)
                     /locus_tag="ACFOV4_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC7619268.1"
                     /translation="MISVEHVSKRYLTRQGWRTVLHDISFKMEKGEKIGILGRNGAGK
                     STLIRLISGVEPPTTGEIKRTMSISWPLAFSGAFQGSLTGMDNLRFICRIYNVDIDYV
                     KNFTEEFSELGQYLYEPVKRYSSGMKARLAFALSLAVEFDCYLIDEVIAVGDSRFADK
                     CKYELFEKRKDRSIILVSHSHSAMKQYCDNAMVLEKGHMHQFEDMDKAYEYYNSLP"
     gene            complement(11341..12138)
                     /locus_tag="ACFOV4_001261"
     CDS             complement(11341..12138)
                     /locus_tag="ACFOV4_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFC7619269.1"
                     /translation="MKALHKTSFWESLAIQRRVIGALLMREIITRYGRNNIGFLWLFV
                     EPLLMTFVIVLMWKFLRADRYSTLNIVAFAITGYPMLMMWRNASKRAVGSISSNASLL
                     YHRNVRVLDTILARMILEIAGATIAQIVIMAVLIAIGWIEMPADMFYMLMAWLLMAFF
                     AIGLGLVICSIAFNFEPFGKIWGTLTFVMMPLSGAFFFVHNLPPKVQEYALMIPMVHG
                     TEMFRAGYFGSDVITYENPWYIVLCNLVLLLFGLAMVSKFSKGVEPQ"
     gene            complement(12138..13301)
                     /gene="ctrB"
                     /locus_tag="ACFOV4_001262"
     CDS             complement(12138..13301)
                     /gene="ctrB"
                     /locus_tag="ACFOV4_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide export protein CtrB"
                     /protein_id="HFC7619270.1"
                     /translation="MSEQLPVAVATETKAERKKPKKKSWIKKLSPLFWVTVIIPTVIS
                     LVYFGFFASDRFTSQSSFVVRSPKSQSSLNGLGAILQGTGFARAQDDIYTVGEYMRSR
                     SSLDELRKILPVREFYETKGDAFSRFNGFGFRGEEEAFYQYYKNQVMINFDTVSGIST
                     LNVTSFDALESKKINEALLKQGEALINQLNDRARADTVRYAEEVVKTAAERVKEASQN
                     LTDYRIANGVFDLKAQSEVQMGLVSKLQDELIVIQTQLDQVKAVTPENPQIPGLQARE
                     QSLRKEIDQQLRAISGGGHSSLSNQAAEYQRVYLENQLAEQQLAAAMTSLESAKVEAD
                     RQQLYLEVISQPSLPDLAHEPKRLYNIVATLIIGLMVYGILSLLTASIREHKN"
     gene            complement(13316..14491)
                     /gene="ctrA"
                     /locus_tag="ACFOV4_001263"
     CDS             complement(13316..14491)
                     /gene="ctrA"
                     /locus_tag="ACFOV4_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide export outer membrane
                     protein CtrA"
                     /protein_id="HFC7619271.1"
                     /translation="MFKVKFYIRHAVLLLCGSLIVGCSAIPSSGPSAKKIVSLGQQSE
                     VQIPEVELIDVNHTVAQLLYKAQINQSFTQFGDGYASAGTLNIGDVLDIMIWEAPPAV
                     LFGGGLSSMGSGSAHQTKLPEQLVTARGTVSVPFVGDISVVGKTPGQVQEIIKGRLKK
                     MANQPQVMVRLVQNNAANVSVIRAGNSVRMPLTAAGERVLDAVAAVGGSTANVQDTNV
                     QLTRGNVVRTVALEDLVANPRQNILLRRGDVVTMITNPYTFTSMGAVGRTQEIGFSAR
                     GLSLSEAIGRMGGLQDRRSDARGVFVFRYTPLVELPAERQDKWIAQGYGSEAEIPTVY
                     RVNMADAHSLFSMQRFPVKNKDVLYVSNAPLAEVQKFLSFVFSPVTSGANSINNLTN"
     gene            14626..15759
                     /gene="neuC"
                     /locus_tag="ACFOV4_001264"
     CDS             14626..15759
                     /gene="neuC"
                     /locus_tag="ACFOV4_001264"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFC7619272.1"
                     /translation="MKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKT
                     YGRTYKEVTRENYQHTYLFSNQIQGEPMGAVLGNTITFISRLSDEIEPDMVMIHGDRL
                     EALAGAAVGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVTRLVQMG
                     EKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYA
                     AQYFKALELSGQNIISIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHA
                     KFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSIIHTDYETKNIFDAIQQACSLG
                     KFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL"
     gene            15763..16449
                     /gene="neuA"
                     /locus_tag="ACFOV4_001265"
     CDS             15763..16449
                     /gene="neuA"
                     /locus_tag="ACFOV4_001265"
                     /EC_number="2.7.7.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acylneuraminate cytidylyltransferase"
                     /protein_id="HFC7619273.1"
                     /translation="MEKQNIAVILARQNSKGLPLKNLRKMNGISLLGHTINAAISSKC
                     FDRIIVSTDGGLIAEEAKNFGVEVVLRPAELASDTASSISGVIHALETIGSNSGTVTL
                     LQPTSPLRTGAHIREAFSLFDEKIKGSVVSACPMEHHPLKTLLQINNGEYAPMRHLSD
                     LEQPRQQLPQAFRPNGAIYINDTASLIANNCFFIAPTKLYIMSHQDSIDIDTELDLQQ
                     AENILNHKES"
     gene            16450..17499
                     /gene="siaC"
                     /locus_tag="ACFOV4_001266"
     CDS             16450..17499
                     /gene="siaC"
                     /locus_tag="ACFOV4_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialic acid capsule biosynthesis protein
                     SiaC"
                     /protein_id="HFC7619274.1"
                     /translation="MQNNNEFKIGNRSVGYNHEPLIICEIGINHEGSLKTAFEMVDAA
                     YNAGAEVVKHQTHIVEDEMSDEAKQVIPGNADVSIYEIMERCALNEEDEIKLKEYVES
                     KGMIFISTPFSRAAALRLQRMDIPAYKIGSGECNNYPLIKLVASFGKPIILSTGMNSI
                     ESIKKSVEIIREAGVPYALLHCTNIYPTPYEDVRLGGMNDLSEAFPDAIIGLSDHTLD
                     NYACLGAVALGGSILERHFTDRMDRPGPDIVCSMNPDTFKELKQGAHALKLARGGKKD
                     TIIAGEKPTKDFAFASVVADKDIKKGELLSGDNLWVKRPGNGDFSVNEYETLFGKVAA
                     CNIRKGAQIKKTDIS"
     gene            17651..20764
                     /locus_tag="ACFOV4_001267"
     CDS             17651..20764
                     /locus_tag="ACFOV4_001267"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC7619275.1"
                     /translation="MAVIIFVNGIRAVNGLVKSSINTANAFAEEGLDVHLINFVGNIT
                     GAEHLSPPFHLHPNVKTSSIIDLFNDIPENVSCRNIPFYSIHQQFFKAEYSAHYKHVL
                     MKIESLLSEEDSIIFTHPLQLEMYRLANNNIKSKAKLIVQIHGNYMEEIHNYEILARN
                     IDYVDYLQTVSDEMLEEMHSHFKIKKDKLVFIPNITYPISLEKKEADFFIKDNEDIDN
                     AQKFKRISIVGSIQPRKNQLDAIKIINKIKNENYILQIYGKSINKDYFELIKKYIKDN
                     KLQNRILFKGESSEQEIYENTDILIMTSQSEGFGYIFLEGMVYDIPILAYNFKYGAND
                     FSNYNENASVFKTGDISGMAKKIIELLNNPEKYKELVQYNHNRFLKEYAKDVVMAKYF
                     TILPRSFNNVSLSSAFSRKELDEFQNITFSIEDSNDLAHIWNFELTNPAQNMNFFALV
                     GKRKFPMDAHIQGTQCTIKIAHKKTGNLLSLLLKKRNQLNLSRGYTLIAEDNSYEKYI
                     GAISNKGNFEIIANKKNSLVTINKSTLELHEIPHELHQNKLLIALPNMQTPLKITDDN
                     LIPIQASIKLEKIGNTYYPCFLPSGIFNNICLDYGEESKIINFSKYSYKYIYDSIRHI
                     EQHTDISDIIVCNVYSWELIRASVIESLMEFTGKWEKHFQTSPKIDYRFDHEGKRSMD
                     DVFSEETFIMEFPRKNGIDKKTAAFQNIPNSIVMEYPQTNGYSMRSHSLKSNVVAAKH
                     FLEKLNKIKVDIKFKKHDLANIKKMNRIIYEHLGININIEAFLKPRLEKFKREEKYFH
                     DFFKRNNFKEVIFPSTYWNPGIICAAHKQGIKVSDIQYAAITPYHPAYFKSPKSHYVA
                     DKLFLWSEYWNHELLPNPTREIGSGAAYWYALDDVRFSEKLNYDYIFLSQSRISSRLL
                     SFAIEFALKNPQLQLLFSKHPDENIDLKNRIIPDNLIISTESSIQGINESRVAVGVYS
                     TSLFEALACGKQTFVVKYPGYEIMSNEIDSGLFFAVETPEEMLEKTSPNWVAVADIEN
                     QFFGQEK"
     gene            20845..21480
                     /locus_tag="ACFOV4_001268"
     CDS             20845..21480
                     /locus_tag="ACFOV4_001268"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HFC7619276.1"
                     /translation="MYSEQGINNTINISTTSLTNATQLTVIGNNNSVYIGNNCKIVSS
                     NIRLKGNNITLFIADDVEIMGLVCSLHSDCSLQIQAKTTMGNGEITIAEKGKISIGKD
                     CMLAHGYEIRNTDMHPIYSLENGERINHGKDVIIGNHVWLGRNVTILKGVCIPNNVVV
                     GSHTVLYKSFKEPNCVIAGSPAKIVKENIVWGRKMYHSTMYDDPTLNEFYK"
BASE COUNT         5869 a         4840 c         4873 g         5898 t
ORIGIN      
        1 gaaaaagacc tgcgctatat cggggaatga atcgacgcaa aggaaatgcc gtctgaacat
       61 gcgttcgggc ggcgttttta taacaaaaac acttcatggc ggttggtttt atgcctgtct
      121 aagtttttgt gtcgtgcata cctgaggatt tcagacggca tcggtttatg ctgtctgaaa
      181 agtgtattcc gtttcagttt gtaagctatg gcagtctgtt tgtcttgtgt tttgcgtaat
      241 tgcccttatt ttgagccgtg attttatttt gaattagatg aaaaaatgag taatcaagat
      301 ttttatgcga cgctgggtgt ggcaagaaca gctaccgatg atgagattaa aaaagcctac
      361 cggaaattgg cgatgaaata ccatcccgac cgcaatcctg acaataaaga ggcggaagag
      421 aagtttaaag aagtacaaaa ggcgtatgaa actttgtccg acaaggaaaa gcgcgctatg
      481 tacgaccagt atggtcatgc ggcgtttgaa ggcggcggac aggggggctt cggagggttt
      541 ggcggatttg gcggtgcgca gggttttgac tttggggata ttttcagcca aatgtttgga
      601 ggcggttcgg ggcgcgccca gcctgattat cagggtgagg acgttcaagt cggtatcgaa
      661 atcacgcttg aagaagccgc aaaaggtgtg aagaaacgca tcaatattcc gacttatgaa
      721 gcgtgtgatg tctgtaacgg cagtggcgcg aaaccgggga catccccgga aacctgcccg
      781 acttgcaaag gttcgggtac ggtgcacatc cagcaggcga ttttccgtat gcagcagact
      841 tgtccgacct gccacggtgc gggcaaacac attaaagaac cttgcgtcaa atgccgtggc
      901 gcggggcgga ataaggcggt caagacggtg gaagtcaata ttcccgccgg tatcgatgac
      961 gggcagcgta tccgtttgag cggcgaaggc gggccgggta tgcacggtgc gcctgccggc
     1021 gacttgtatg taaccgtccg cattcgggcg cataagattt tccaacgcga cggtctggac
     1081 ttgcattgcg aactgccgat cagttttgcc acggctgctt tgggcgggga gttggaagtg
     1141 ccgaccttgg acggaaaggt caagctcacc gtccccaaag aaacccaaac cggcaggagg
     1201 atgcgtgtga aaggtaaggg tgtcaaatcg ttgcgcagca gcgcgaccgg cgatttgtac
     1261 tgccatattg ttgtcgaaac gcctgtcaat ttgactgacc gtcaaaaaga gcttttggaa
     1321 gagtttgagc ggatttctac cggcttggaa aaccaaacac cgcgcaagaa atcgttttta
     1381 gacaagctgc gcgatttgtt tgattgattt taaggttcgg aaacaagcag ccgtatcggg
     1441 gaatctcctt gatacggctg tttttatttg tttaaaaata gtttttattt tcaatggggt
     1501 atgaggcagg gtgggataac tgtttttaac tgttcttttt aaaacttgac atcatggcgt
     1561 gatgccaaca atatgtgaac gtctgttgtc aaaggaagaa taatgaataa atctttatcc
     1621 agttcggtag aagaataccg cgagctgacg ctccgaggca tgatactcgg tgcattgatc
     1681 actgtaattt ttactgcgtc caatgtttac ctcggtttga aagtcgggct gacctttgcc
     1741 tcgtcgattc cggcggcggt gatttcgatg gcggttttaa agtttttcaa aggcagcaat
     1801 attttggaaa acaacatggt gcagacccaa gcttcggcgg cgggtacgct ttcgaccatc
     1861 atcttcgtcc tgcccggttt gctgatggcg ggctactgga gcggtttccc gttctggcag
     1921 acgacgcttt tatgtattgc cggcgggatt ttgggggtga ttttcaccat tccgctgcgt
     1981 tacgcgatgg tggtgaaaag cgatttgcct tatccggaag gtgtggcggc tgctgaaatt
     2041 ttgaaagtgg gcggtcatga agaaggggat aaccgtcagg gcggcagcgg catcaaagag
     2101 ctggcggccg gcggtgcgtt ggcgggattg atgagctttt gcgccggagg tctgcgcgtg
     2161 attgccgaca gcgcgagtta ttggtttaaa agcggtacgg cgattttcca gctgccgatg
     2221 ggcttttcac tggcattgtt gggcgcgggc tatttggtcg gactgacggg cggtatcgcc
     2281 atcctgttgg gcatttcgat tgcttggggc attgccgtgc cgtatttctc ctcacacatt
     2341 ccgcaacctt ccgatatgga aatggcggcg tttgcgatga agctgtggaa ggagaaagtg
     2401 cgttttatcg gtgcggggac tattggcatt gcggcggttt ggacgctgtt gatgctgctc
     2461 aagccgatgg tggaaggcat gaagatgtcg ttcaagagtt ttggcggcgg tgcgcccgct
     2521 gcggaacgcg ccgaacaaga tttgtcgcct aaagccatga ttttttgggt gctggcgatg
     2581 atgtttgttt taggcgtgtc gttttaccac tttatcggcg attcgcacat tacgggcggc
     2641 atggcttggc ttttggtggt cgtttgcacg cttttggctt ccgtcatcgg ctttttggtc
     2701 gccgccgcct gcggttatat ggcaggtttg gtcggctcgt cttccagccc gatttccggc
     2761 gtgggcatcg tgtccgtcgt cgttatttca ctggttttgc tgctggtagg cgaatccgga
     2821 ggtttgttgg cggatgaggc taaccgcaaa tttttgctgg cactgacttt gttttgcggc
     2881 tcggcagtaa tctgcgtggc ttcgatttcc aatgacaacc tgcaagactt gaaaaccggc
     2941 tacctgctca aagccacgcc ttggcggcag caagtcgccc tgattatcgg ctgtatcgtt
     3001 ggtgcgctgg ttatttcgcc cgtgttggaa ctgctttacg aagcctacgg ctttaccggc
     3061 gcaatgccgc gcgaaggcat ggatgcggcg caggctttgg cagctcctca agcgactttg
     3121 atgacgacca tcgcgtcggg cattttcgcc cacaacctcg aatgggtcta catctttacc
     3181 ggcatcgcga tcggcgcggt attaatcgtc gtcgatttgg tgttgaaaaa atcatcaggc
     3241 ggcaaacttg ccctgcccgt ccttgcggtc ggtatgggta tttatctgcc gccgtccgtc
     3301 aatatgccca tcgtggcagg cgcggtgttg gcggcggtgt tgaaacacat catcggtaaa
     3361 aaagcggaaa accgcgaagg ccgtctgaaa aacgccgagc gtatcggaac cttgttctcc
     3421 gccggcctga ttgtcggtga aagcctgatc ggtgtgatta tggcgtttat tattgccttc
     3481 tccgtgacca acggcggctc ggatgcgccg cttgcgttga atctgcaaaa ctgggatgcc
     3541 gccgcttctt ggttgggttt ggcgttcttc gttaccggga tgtttttctt tgcacagcgc
     3601 gtactgaagg cgggcaagta ggctgtcgga aaaaatgccg tctgaagcgt tcagacggca
     3661 tttttatctg gaaagcggaa ggcggagctt ttcggcttgc gcccacgttt tgccggcaag
     3721 gtctttgggc gacagcagcg gcgcggttta aagcggccag cctatgccga ctgtcgggtc
     3781 gttccatatt aaaacctgtt cggcttcagg cttgtaatag tcggtgcatt tgtacacgac
     3841 ttccgccgcg tcgcccaaaa cgcaaaaccc gtgcgcgaag ccttcgggta tccaaagctg
     3901 gcattggttt tgcgcggaca gggttgcgcc cgcccatttg ccgaaagtcg gcgaaccttc
     3961 gcgcatatcg acggccacgt cgaacacttc gccgacaact acgcgtacga gtttgccttg
     4021 tgtgttttcg gtttggtagt gcaggccgcg caatacgcct ttgccggatt tggagtggtt
     4081 ttcctgcacg aaggtgcgtt cgcagacttg ggttttaaac cactcgtcgc ggaaggtttc
     4141 cataaaaaag ccgcgcgcgt cgccgaagac ttggggctca agcagtttta cgtcaggaat
     4201 ggcggtatca atgatgttca tctttttatc tttcatctaa aggccgtctg aaaagtttca
     4261 gacggcctca aacattattt tttcaacagg cgcagcaaat attggccgta ttggtttttc
     4321 gccatcgggc gcgccaattc ttccagtttt tcatcggaaa gccaaccgtt gcgccaagcg
     4381 atttcttcca ggcaggcgat gtgcaggttt tggatgtttt gcacggtttg gacgaatgaa
     4441 gcggcttcgt gcaggctctc gtgggtgccg gtgtccaacc atgcgaaacc gcgtcctaat
     4501 atttggacgg acaatgaacc gtcttccaaa tacatttggt tgaggtcgga aatttccaat
     4561 tcgccgcgtg cggacggttt gagctgtttg gcgaactcga cggcgcggtt gtcgtagaaa
     4621 tacaagccgg ttaccgccca atcggatttg ggccgttgcg gtttttcttc gatggaaacg
     4681 gcgcggaagt tttcgttaaa ttcaaccacg ccgaaacgtt cggggttttt gacctgataa
     4741 gcaaacacgg ttgcgccgtg cgtttgcgct gccgcctgtt tcaatgtttg cgtaaacgac
     4801 tgaccgtaaa aaatattgtc gcccaaaacc aagcaaacat tgtcgttgcc gataaattct
     4861 tcgccgatga taaatgcctg tgccaagccg tccggactgg gttgcacggc ataactgatg
     4921 gaaatgccga aatcgctgcc atcgccaagc aggcgtttga aagaggcgtt gtcttcaggc
     4981 gcggtaatca ccaaaatatc gcggattccc gccagcatca aaaccgacaa ggggtaataa
     5041 atcatcggtt tgtcgtacac gggcaggagc tgtttggata cgccgcgcgt gatggggtag
     5101 aggcgcgtgc cgctgccgcc tgccagtatg atgcctttca tcttttcttt cttcctttgc
     5161 gatgggtttt cagacggcat tgcgtcggga tgccgtctga aaactatttt ccagtaccta
     5221 aacgttccaa acgatagctg ccgttcaata cattttgcca ccaggttttg ttgtccagat
     5281 accattgcac ggttttgcgg aggccggact cgaaggtttc caaaggcagc cagcccaaat
     5341 cccgcctgat tttggctgcg tcgacggcgt agcgtacgtc atggccgggg cggtcttgta
     5401 cgaaagtaat caaatcttca taacgcgcca caccggccgg tttttcggga gcgagttctt
     5461 ccagcagggc gcagatggtt ttgacgactt caatattggc tttttcattg tggccgccga
     5521 tattgtaggt ttcgccgaca acaccttcgg taacaacctg atacagtgcg cgcgcgtggt
     5581 cttcgacaaa cagccagtcg cggatttgca taccgtcgcc gtacacaggc agcggtttgc
     5641 cgtcaagcgc gttcagaatc atcaaaggaa tgagtttttc cggaaaatgg taaggaccgt
     5701 agttgttgga gcagttggtt acaatggtcg gcaagccgta agtacgcaac cacgcgcgga
     5761 cgaggtggtc gctggacgct ttagaggcag agtaagggct ggacggcgcg tagggcgcgg
     5821 tttcggtaaa caaatcgtct gtgccgctta aatcgccata aacttcatcg gtagaaatat
     5881 ggtggaaacg gaaggcttcg tgcttttcag acggcatttg ctgccggtag gcacgcgcag
     5941 cttcaagtag gttgaatgtg ccgacgatat tggtttggat aaactcgcct gccgaaccga
     6001 tagagcggtc gacatggctt tccgccgcca agtgcatcac ggcatcgggc cggtgttgtg
     6061 cgaatacgcg gtcgagttcg gcgcggtcgc aaatgtccac ttgctcgaaa gcatagcggg
     6121 gattatcggc aatgtcggtc agcgattcga gattgcccgc gtaggtcagt ttgtcgaggt
     6181 tgacgacgga atcttgggtg tttcggataa tatgacggac aacggcagag ccgataaagc
     6241 ccgcaccgcc ggtaacgagg atggtttttt tgtttgcggt ttgcatttag tccccgtatc
     6301 cgtcggggtt gcggctgacc caacgccacg aatcctccat catttgtttc aaaccgcgtt
     6361 tggtttccca gcccgtctct tgtttggtat gggacgggtc ggcaaaggaa cacgccaagt
     6421 ctccggcgcg tcggggttgg atttgatagg gaatatttaa gccggatgcg gcctcaaagg
     6481 cacggatgat ttctaagacg gaataggcgc ggcccgaacc caagttgaac aaatgtacgc
     6541 cggaaaggcc gcctttcgcc ttcattgccg cgatatgccc ttctgccaaa tccatcacat
     6601 gaatatagtc acgcatcccc gtgccgtcgg gggtagggta gtcatcgcca aataccgcca
     6661 attgcggcag tttgcctgcc gccacttggc agatataagg caacaaatta ttcgggatgc
     6721 cgtttggctg ctcgccaatc aaaccacttt cgtgcgcgcc aatcggattg aaataacgca
     6781 acaaaatcac gctccagcgc ggatcggcct tttggatgtc ggttaacatc cgttccacca
     6841 tcgctttgga tgcgccataa ggattagcgg tatcgcccgg gcgcatatct tccgtatagg
     6901 gcattttacg tatcatggcg cgacgcatta aagtaaacgc caaagcgcgt ttatactggt
     6961 tatccagttt ccctatattt ttacgttaca aatcaagttg ttggtattca tcgtgaaaat
     7021 agaatttttc ggcataacgc tgactcataa aaccggcatg cgggctacct gaaaaaatca
     7081 ttgcgccatc atcgtcattt aatgtttcat ggttgttttc tattaatgct aaagcaattt
     7141 ggtaattaat tgccaaaata tcgttagtaa tcacacgata gccgcgtttt ttggcttcgt
     7201 aggcaaagga acagcctcca ctaaatacat ctgcaactgt atctacatca gacggaagct
     7261 ggtcacaaat ccaggaagct attttctctt tattaccgat atagttaatt ttcggatatt
     7321 gcttattcat tttcactcat ttttaaaata ctttcagcaa tagcttttgc caataaaggc
     7381 ggtacggcgt taccaacctg ctgctgctgg gcaattttgc tgccgcaaaa aataaaatta
     7441 tcagggaaag attgtaaggc agctaattca cgaacggtta acgcccgatt ctgttcatag
     7501 tgaaaaactt tgcgcatatc tcctgtaata caaacggctg gttttgttgc tgttgtaacg
     7561 gatgtattta cggatatcac ctgttttcgg acgtaatggt tcaggaatat cgttacggtt
     7621 acctccattt ttaacaaatg ccattttttc taacatttgt gccgaatgat tcatagcttc
     7681 atgatttgca acgtgtggat tgctttcgcc agcagccagt tttggaaaat gtcctattgc
     7741 tgatccaaca gtctgatggg aaatctgcaa aggttcggga aaggaaattt tgcctttatc
     7801 cctcctcccg ataaatatca ctcggctacg tatctgagga acaccgaaat cggctgcact
     7861 cagtatctta cattccaccg aataaccgat attctgaaat gcttgaataa tctcaatacg
     7921 tgttttacct gaattgtgtg tatagagtcg cgctacattt tccataacaa aaaaatatgg
     7981 ttggacaatt ttaactattc ggacaaactc tttaaataaa tggttgcgtg ggtcatctgt
     8041 aaatgtccgt ccaatctttc ctgccatact aaaaccttga caaggtggtc ctccaataat
     8101 caaatcaact gcttgtccgt taagacaatt gattaaatct tgttcggtta gtgtggttaa
     8161 atctttttgc agtaattgat gatgggggaa gttggtacgg taagtctgac aataatcaga
     8221 ctccatttca acagaaagca attgttggaa tccggcttgt tcaaaaccca aggataggcc
     8281 tcctgctcct gagaaaaggt caatataggt aagtggtgtg tgcataagtc aaaatccata
     8341 aactcttcga ttattttacc gcttcagctt cgcaaacgca tccgccatcg ccgaattggc
     8401 tggggcgcgg tcgttgcgtt ggggtttgcg gccggctgtc cgttcgcggc tgcggttttc
     8461 agacggcatt ttatgttttg cgccgcccgg ttcgtcatcc aagcgcatgg tcagcgcgat
     8521 gcgtttgcgt gcagcatcga cttccagcac tttcactttc accacgtcgc cagctttcac
     8581 cacttcgcgc gggtcttgga cgaacttgtt ggacagggcg gagatgtgca ccaagccgtc
     8641 ctgatggacg ccgatgtcca cgaacgcgcc gaagttggcg acgttggaaa ccacgccttc
     8701 gagtatcata ccgacttgca agtcgctgat ttcgtggata ccttcggcaa acgatgccgt
     8761 ctgaaactcg ccgcgcggat cacggccggg tttttccagt tcggacagga tgtccaaaat
     8821 ggtcggcagg ccgaagcgtt cgtcggtgaa gtcggacgct ttgatttgct tcacgcgctc
     8881 gcggttgccg atgagttcgg cggcgctaat gccttgttgc gccagcattt tggcgacgac
     8941 gggataggct tcggggtgga cggcgctcgc gtccaacggc tctttgccgc cgttaatccg
     9001 caaaaagccc gccgcctgct cgaaggtttt ttcgcccaaa cgcggtactt tcagcaattt
     9061 tttgcggctg tcgaacgcgc cgttttcatc gcggtaggcg acaatgtttt gggcaagggt
     9121 ttgattcaaa ccggaaattc gcgccaagag cggggcggag gcggtgttca cgtccacgcc
     9181 gacggcgttc acgcagtctt cgaccaccgc gtccagcgat ttggcgagct ggctttggtt
     9241 cacgtcgtgc tgatactgcc ccacgccgat ggatttgggg tcgattttga ccaactcggc
     9301 aagcgggtct tgtagcctgc gggcgatgga caccgcgccg cgcagggaaa cgtccaagtc
     9361 ggggaactcg cgcgccgcca gttcggacgc ggaataaatc gacgcgccgg cttcggacac
     9421 gacgatttta tgcagcccca ttttcgacat ttcacgcacc agttcgcccg cgattttgtc
     9481 ggtttcacgg ctggcggtgc cgttaccgat ggcgatgagc ttcacgccgt gctgtttaat
     9541 caggcgcgac agcgttgcca acatattgtt ttcttgatgc aaatagacga tgacggtatc
     9601 cagcagcttg cccgtgtcgt ccaccacggc acatttcacg ccgttcttgt atccagggtc
     9661 gagacccagc gtggtcagcc gtccggcggg tgcggcgagc agcaagtctt tgagatttcg
     9721 ggcaaacacg gtaatcgcgt cggtgtcggc ggcttctttc aaacgattga gagcttcgag
     9781 ttccaacgac aaaaagattt ttgcgcgcca agtcagacgc acggtgtcgc gcagccattt
     9841 gtggccgtct gaaaccttga aacggcgggc gatgatttgc tcgtattcgc tttgctgcgt
     9901 aatcggcgtg tcgtcgggcc ggtatttgag cgcgatgttc aacacgcctt cgttgcggcc
     9961 gcgcaaaacc gccaacgcgc ggtggccggg catagtgcgg acgggttcgc ggtggtcgaa
    10021 ataatcgctg aatttttcgc cttcggtttc tttgcctcca acaacttgcg cgtggatttc
    10081 ggcttcgttc cacagcttgt cgcgcagcgt gccgatgagt tccgcgtctt cggcaaactg
    10141 ctccatcaga atcgcacgcg cgccgtccaa cgcggctttg gcatcgggga cgttttcgtt
    10201 caggtagcct tgtgcggcgg cttccacgtc ctgcgactgc tcggcaagca acacgtccgc
    10261 cagcggctgc aaaccgtgtt cgcgcgcgat ttgcgctttg gtgcggcgtt tgggtttgta
    10321 gggcagatac aggtcttcca gcgcggtttt gttatcggcg gcttcgattt gcgccctgag
    10381 gtcgtctgaa agcttgcctt gctcttcaat gctttttaaa acaacggctt tgcgctcttc
    10441 caactcgcgc aggtattgca gccgctcggc aagccggcgc agctgcgtat cgtccaaccc
    10501 gcccgtggct tccttgcggt agcgggcgat aaagggcacg gttgcgccgt cgtccaaaag
    10561 ctcgatagcg gcattgattt gcgcggtagt cgcggaaagt tcttgggaaa gaatttgagt
    10621 aatgttcatc aataaaattc caacggacag gccgtctgaa atttcagacg gcctgattta
    10681 aaaaacaatc gctttaaggt agcgaattat aatattcgta ggctttgtcc atatcttcaa
    10741 actggtgcat atgccctttt tccagcacca tcgcattatc gcaatattgc ttcatggcgc
    10801 tgtggctgtg cgacaccaag atgatggaac ggtctttgcg cttttcaaac aactcgtact
    10861 tacatttatc ggcaaagcgc gagtcgccaa ctgcaatcac ttcgtcaatc agatagcaat
    10921 caaactctac cgccaacgac aaagcaaatg ccaaacgcgc cttcatacct gaagaataac
    10981 gcttgaccgg ctcgtaaaga tattgcccca actcggaaaa ctcttcggta aagttcttca
    11041 cataatcgat atcgacattg taaatccggc agatgaaacg caaattgtcc ataccggtca
    11101 gactgccttg aaacgcaccg gagaatgcca aaggccaaga aatactcatt gtccgcttga
    11161 tttcacccgt ggtcggcggc tcaacgccac tgatcaaacg gatgagcgtc gatttacctg
    11221 caccgttgcg gccgagaata ccgattttct cgcccttctc cattttgaag ctaatatcgt
    11281 gcaagactgt ccgccaacct tggcgggtca gatagcgttt ggaaacgtgt tcaactgaaa
    11341 tcattgcggc tcgactcctt tactgaattt actgaccatc gccaagccaa acaacaacaa
    11401 caccagattg cacaatacga tataccaagg attttcatag gtaattacat cgctgccaaa
    11461 atatccggca cggaacattt ctgtgccatg caccatcgga atcattaatg catattcttg
    11521 taccttgggc ggcaaattat gcacaaaaaa gaacgcaccg gataacggca tcatcacaaa
    11581 agtcaatgtg ccccaaatct tgccaaacgg ctcgaaatta aaggcaatcg aacaaatcac
    11641 caaacccaaa ccaatcgcaa aaaaagccat caaaagccaa gccatcagca tataaaacat
    11701 atctgccggc atttcaatcc agccaatcgc aatcaatacc gccataatca caatctgcgc
    11761 aatggttgca ccagcaattt ccaaaatcat gcgcgccaag atggtatcca aaactcttac
    11821 attgcggtga taaagcaagc tggcatttga agaaatcgac ccaactgccc gttttgaggc
    11881 attacgccac atcatcaaca tcggatagcc agtaatcgca aatgcgacaa tattcaaagt
    11941 tgaatatcgg tctgccctta aaaatttcca catcaagacg ataacgaatg tcatcagcaa
    12001 cggctcaaca aacagccata aaaagccaat attattgcga ccgtaacggg tgataatttc
    12061 ccgcatcaac agcgcaccga ttacgcgcct ttgaatggct aaagattccc aaaatgatgt
    12121 tttatgcaag gctttcatca gtttttatgc tcacgaatgc tggcagtcaa caggctcaaa
    12181 ataccataaa ccatcaagcc gataatcaga gtggcaacaa tgttgtataa ccgtttaggc
    12241 tcatgtgcca aatccggcag gctcggttgc gagatcactt ccaaataaag ctgctgacgg
    12301 tctgcttcaa ccttggcact ttccaaagaa gtcatggcgg ctgccaactg ctgctctgcc
    12361 aactggtttt ccaaatacac acgctgatat tcggcagcct gattagacaa cgaagaatgc
    12421 ccaccgcccg aaatggcacg taactgttgg tcaatttctt tacgcaagct ctgctcacgc
    12481 gcctgcaaac ccggaatctg cggattctcc ggagtgactg ctttcacctg atccagctgg
    12541 gtttgaatca caatcaattc atcttgcagc ttggaaacca accccatttg cacttccgat
    12601 tgcgctttca aatcaaaaac gccattggca atccggtaat ccgtcagatt ctgagaggct
    12661 tcctttaccc gctctgccgc cgttttcact acttcttccg catagcgcac cgtatcagca
    12721 cgtgcacgat cgttcaactg gttaatcaat gcttcacctt gttttaacaa agcctcattg
    12781 attttcttag attccagcgc atcaaaggaa gttacattca acgtggaaat acccgaaacc
    12841 gtatcaaaat tgatcatcac ctgattttta tagtattgat aaaaagcctc ttcctcgcca
    12901 cggaacccaa acccattaaa gcggctgaac gcatcacctt tggtttcata aaactcacgc
    12961 actggcaaga ttttacgcag ttcatccaaa gacgagcgcg aacgcatata ctccccaacc
    13021 gtgtaaatat catcttgcgc acgggcaaaa cctgtgccct gcaaaatggc acccaggcca
    13081 ttgagagaag attggctttt aggcgagcgc accacaaagc tcgattgcga cgtaaaacga
    13141 tcggaagcga agaagccgaa atacaccaac gaaattaccg tagggataat caccgttacc
    13201 caaaataaag ggcttagctt tttaatccaa cttttctttt tcggcttttt acgctcggct
    13261 ttggtttcag tggcaactgc cacaggaagt tgctcagaca tcttaattac tcacattaat
    13321 tagttaaatt attaatactg ttcgcgccac tggtaaccgg cgagaacaca aacgacaaaa
    13381 atttctgcac ttcagccaac ggcgcattcg acacatacaa tacatcttta ttcttcacag
    13441 gaaagcgctg catagaaaat agcgaatgcg catcagccat attcacacga tataccgttg
    13501 gaatctctgc ctcactgcca taaccttgag caatccattt atcctgacgt tctgccggca
    13561 attccaccaa tggcgtatag cggaacacaa acacaccacg cgcatcagaa cggcgatctt
    13621 gcaaaccgcc catacggcca atggcttcag aaagcgataa gcctctggct gaaaaaccga
    13681 tttcttgtgt tctccccacc gcacccatag acgtaaaggt atagggattg gtaatcatgg
    13741 taaccacatc accgcgacgc agcaaaatat tttgtcgcgg atttgcaact aaatcttcca
    13801 aggcaacagt tcgtactaca ttgccacgtg tcagctgcac attcgtatcc tgcacatttg
    13861 ccgttgaacc acctaccgca gccaccgcat ccaacacacg ctcaccggct gccgtcagcg
    13921 gcatacgcac actattccca gcacgaatca ccgacacatt cgccgcatta ttctgcacca
    13981 aacgcaccat cacttgtggc tgattggcca tttttttcag gcggccttta ataatttcct
    14041 gaacctgacc aggcgtttta ccgaccaccg aaatatcgcc aacaaacggc acagaaaccg
    14101 taccacgtgc cgtgaccaac tgctctggca acttagtttg atgcgcacta cccgagccca
    14161 tcgaagaaag gccaccacca aacaatactg ccggcggcgc ttcccaaatc ataatatcca
    14221 atacatcacc aatatttagc gtaccagccg aagcataacc atcgccaaac tgagtgaatg
    14281 actgatttat ctgagcctta tataataact gagcaaccgt atgattcaca tcaatcagct
    14341 ccacttcagg aatttgaact tcagattgtt gccctaaaga gacaattttt tttgcgctgg
    14401 ggcctgatga aggaatcgca gagcatccta caattaaact tccacacaat aataatactg
    14461 cgtgacgaat ataaaatttc actttaaaca caagccaaat cctaatataa ttataaatgg
    14521 cctaattata gcacttaatc gaaataaatt tatgagtacg tagagtataa ttagtattct
    14581 tctttccaac ttccttatac ttatatactt atagattcta aaatcatgaa aagaattctt
    14641 tgcattacag gtaccagagc cgacttcggc aagctaaaac ctttattagc ctatattgaa
    14701 aatcacccag accttgaatt gcatttgatt gtaactggta tgcatatgat gaaaacatat
    14761 ggcagaacct acaaggaagt aactcgagaa aactatcaac atacatatct gttttcaaat
    14821 caaatccaag gtgaaccaat gggtgccgtt ttaggcaata ccattacgtt tatctctcgt
    14881 ctatctgatg aaattgaacc tgatatggtc atgattcacg gcgaccgttt agaagcacta
    14941 gcaggcgcag ctgtaggtgc attaagcagc cgtttagttt gccatatcga aggtggtgaa
    15001 ctatctggta cagtagatga ctccattcgt cattctatta gtaaactttc tcatatccac
    15061 ttggtagcaa atgaacaagc tgtcactcgc ctagtgcaaa tgggagaaaa aagaaagcat
    15121 attcacatca tcggctcccc cgatttagat gttatggcct cttccaccct cccatcctta
    15181 gaagaagtca aagaatatta cggtttacca tacgaaaatt atggtatttc tatgtttcac
    15241 cccgtgacta cagaagcaca tttaatgcca caatatgcgg cccaatattt caaagcatta
    15301 gaattaagtg gccaaaatat cattagcatc taccctaata atgacactgg cactgaaagt
    15361 attctgcaag aattattaaa atatcaatct gataaattta ttgcatttcc ttccattcga
    15421 tttgaatatt ttttagtctt attgaaacat gctaaattta tggtcggcaa ctcaagtgca
    15481 ggtattagag aagctcctct ctacggtgtc ccttcaattg atgttggtac acgccaaagt
    15541 aaccgccata tgggaaaatc tattattcat acagattatg aaactaaaaa tatctttgat
    15601 gcgattcaac aagcatgcag tttaggcaaa tttgaagcag atgatacctt taatggcgga
    15661 gatactcgca ccagcacaga aagatttgct gaagtaatca acaatcctga aacgtggaat
    15721 gtttctgctc aaaaacgttt tatcgatttg aatctttaaa ttatggaaaa acaaaatatt
    15781 gcggttatac ttgcgcgcca aaactccaaa ggattgccat taaaaaatct ccggaaaatg
    15841 aatggcatat cattacttgg tcatacaatt aatgctgcta tatcatcaaa gtgttttgac
    15901 cgcataattg tttcgactga tggcgggtta attgcagaag aagctaaaaa tttcggtgtc
    15961 gaagtcgtcc tacgccctgc agagctggcc tccgatacag ccagctctat ttcaggtgta
    16021 atacatgctt tagaaacaat tggcagtaat tccggcacag taaccctatt acaaccaacc
    16081 agtccattac gcacaggggc tcatattcgt gaagcttttt ctctatttga tgagaaaata
    16141 aaaggatccg ttgtctctgc atgcccaatg gagcatcatc cactaaaaac cctgcttcaa
    16201 atcaataatg gcgaatatgc ccccatgcgc catctaagcg atttggagca gcctcgccaa
    16261 caattacctc aggcatttag gcctaatggt gcaatttaca ttaatgatac tgcttcacta
    16321 attgcaaata attgtttttt tatcgcccca accaaacttt atattatgtc tcatcaagac
    16381 tctatcgata ttgatactga gcttgattta caacaggcag aaaacattct taatcacaag
    16441 gaaagctaaa tgcaaaacaa caacgaattt aaaattggta atcgttcagt aggttacaac
    16501 cacgaaccat tgattatctg tgaaatcggc atcaatcatg aaggctcttt aaaaacagct
    16561 tttgaaatgg ttgatgctgc ctataatgca ggcgctgaag ttgttaaaca tcaaacacac
    16621 atcgttgaag acgaaatgtc tgatgaggcc aaacaagtca ttccaggcaa tgcagatgtc
    16681 tctatttatg aaattatgga acgttgcgcc ctgaatgaag aagatgagat taaattaaaa
    16741 gaatacgtag agagtaaggg tatgattttt atcagtactc ctttctctcg tgcagctgct
    16801 ttacgattac aacgtatgga tattccagca tataaaatcg gctctggcga atgtaataac
    16861 tacccattaa ttaaactggt ggcctctttt ggtaagccta ttattctctc taccggcatg
    16921 aattctattg aaagcatcaa aaagtcggta gaaattattc gagaagcagg ggtaccttat
    16981 gctttgcttc actgtaccaa catctaccca accccttacg aagatgttcg attgggtggt
    17041 atgaacgatt tatctgaagc ctttccagac gcaatcattg gcctgtctga ccatacctta
    17101 gataactatg cttgcttagg agcagtagct ttaggcggtt cgattttaga gcgtcacttt
    17161 actgaccgca tggatcgccc aggtccggat attgtatgct ctatgaatcc ggatactttt
    17221 aaagagctca agcaaggcgc tcatgcttta aaattggcac gcggcggcaa aaaagacacg
    17281 attatcgcgg gagaaaagcc aactaaagat ttcgcctttg catctgtcgt agcagataaa
    17341 gacattaaaa aaggagaact gttgtccgga gataacctat gggttaaacg cccaggcaat
    17401 ggagacttca gcgtcaacga atatgaaaca ttatttggta aggtcgctgc ttgcaatatt
    17461 cgcaaaggtg ctcaaatcaa aaaaactgat attagttaat aataaaatag attaagctat
    17521 tcttaaattc agaatattgc ttatctatat taaaaatttc taatttttaa ggttctgatt
    17581 gaaatcagaa ccttatttca actattactt tttactcata atcgaattat atactttagg
    17641 actttataat atggctgtta ttatatttgt taacggaatt cgggctgtaa atggccttgt
    17701 taaatcatct atcaatactg caaacgcttt tgctgaagaa ggactggatg ttcatttaat
    17761 taattttgtt ggcaatatta ctggagcaga gcatttatcc cccccattcc acttacatcc
    17821 caatgtcaaa acctccagca tcatagattt atttaatgac attccagaaa atgttagctg
    17881 ccgaaatatt cctttttatt ctatccatca acaattcttc aaagccgaat acagtgccca
    17941 ctataagcat gttttgatga aaattgaatc tttattatct gaagaagata gcattatctt
    18001 cactcatcct cttcaactgg aaatgtatcg tttagcgaat aataatatta agtcaaaagc
    18061 caagctaatt gtacaaattc atggtaacta tatggaagaa atccataact atgaaatttt
    18121 ggcacgaaat atcgattatg ttgattatct tcaaacggta tctgatgaaa tgctggaaga
    18181 aatgcattcc catttcaaaa tcaaaaaaga caaattagtt tttattccaa acatcactta
    18241 tcccatttca ttagaaaaaa aagaagctga tttctttatt aaggataatg aagacattga
    18301 taatgctcag aaatttaaac gtatctctat tgttggcagt attcagccaa gaaaaaacca
    18361 attggatgcc attaaaatca tcaataaaat taaaaatgaa aattacattt tacagatata
    18421 tggcaaatct attaataaag attactttga attaattaaa aaatatatta aagacaataa
    18481 gttacaaaac cgtatcttat tcaaaggtga atcttccgag caggaaattt atgagaatac
    18541 agatatccta atcatgacat ctcaaagcga aggctttggt tatatatttc tagagggtat
    18601 ggtgtacgat atccctatcc ttgcctataa ttttaaatat ggagcgaatg attttagcaa
    18661 ttataatgaa aacgcttcag tttttaaaac tggtgatatt tctggaatgg caaaaaaaat
    18721 aattgagcta ttaaataacc cagaaaaata taaagaatta gttcaatata atcacaatcg
    18781 cttcttaaaa gaatatgcaa aagatgtggt tatggctaaa tatttcacta ttcttccgcg
    18841 cagctttaat aacgtatcat tatcgtctgc tttcagccga aaagaattgg acgaattcca
    18901 aaatattact ttttctattg aagattctaa tgatttagct catatttgga atttcgagct
    18961 aaccaatcct gcacaaaata tgaatttttt tgctttagtt ggcaagcgaa aatttccaat
    19021 ggatgctcat atccaaggaa cacagtgtac gattaagata gctcataaaa agacagggaa
    19081 tttattgtcg cttttactaa aaaaacgaaa tcagttgaat ttatcaaggg gatatacctt
    19141 aattgcagaa gataatagct atgaaaaata tattggagca atatctaata aaggtaactt
    19201 tgaaattatt gcaaataaaa agaactcatt agttactata aacaaaagta ccttagagtt
    19261 gcatgagatt ccccatgaac tacatcagaa taaattactg attgctttac ccaacatgca
    19321 aacgcctcta aaaattactg atgataattt aatacctatc caagcctcca taaaattaga
    19381 aaagattgga aatacttatt acccatgttt cttgccatct ggcatattta ataatatctg
    19441 cttagattac ggtgaagaat ccaaaattat taattttagt aaatattctt ataaatatat
    19501 ctatgactca attcgtcata ttgagcaaca tacagatata tcggatatta tcgtttgcaa
    19561 tgtttattct tgggaactta ttcgtgcctc agttattgag agccttatgg aatttaccgg
    19621 aaaatgggaa aaacactttc agacttctcc taaaattgat tatcgatttg atcatgaagg
    19681 taagcgttcg atggatgatg tcttttcaga agaaacattt attatggaat ttccgcgtaa
    19741 aaatggtata gataagaaaa cagcagcctt ccaaaatata ccaaacagta ttgtaatgga
    19801 gtatccgcag accaatggtt acagtatgcg cagtcattca ctgaaaagta atgtagttgc
    19861 ggcaaaacat tttcttgaaa aattaaataa aattaaggta gatattaaat ttaaaaagca
    19921 tgaccttgca aacatcaaaa aaatgaatcg aattatttat gagcatttag gcattaacat
    19981 aaatatcgaa gcatttctaa aaccacgatt agaaaaattt aagcgtgaag aaaaatattt
    20041 tcatgatttc ttcaaaagaa ataattttaa agaggtaatt tttccaagca cttattggaa
    20101 tccaggtatt atttgtgctg cacataaaca aggtattaag gtatctgata ttcaatatgc
    20161 tgccattact ccttatcatc ctgcgtattt taaatcacca aaatcacatt acgttgctga
    20221 taaattgttc ttatggtctg aatattggaa tcatgagctt ttaccaaatc caacacgaga
    20281 gattggttct ggtgccgcat attggtatgc attagatgat gtgagatttt cagaaaaact
    20341 gaattatgac tatatctttc tatctcaaag taggatttct tcgcgcttgc ttagttttgc
    20401 aattgagttt gcattaaaaa atcctcaact acagctttta ttttctaagc atccagatga
    20461 aaatatagat ttaaagaaca gaattattcc tgataatctt ataatctcca cggaatcttc
    20521 tatacaaggc atcaatgaat ctcgcgttgc tgtaggtgtt tattcaacta gcttatttga
    20581 ggcattagca tgcggcaaac aaacttttgt tgttaaatat ccgggatatg aaattatgtc
    20641 aaatgaaata gattcagggt tattctttgc agtagaaaca cctgaagaaa tgcttgagaa
    20701 aacaagcccg aattgggtgg ctgtggcaga tattgaaaac cagttttttg gccaagaaaa
    20761 ataattttta agttaatctt taaaagtgca atatttttct tattttaaat attacacttt
    20821 attcttttaa tcataggaac tcacatgtat tctgaacagg gaattaataa tactattaac
    20881 atatctacta catctttaac caatgccacg caactaactg tgatcgggaa taataactct
    20941 gtatatatag gtaataattg taaaatcgtc agctccaata ttagattaaa aggaaataat
    21001 ataaccttat ttatagctga tgatgtagaa atcatgggac tagtatgttc ccttcattcg
    21061 gactgctctt tacaaattca agccaagacc actatgggca atggagaaat taccattgct
    21121 gaaaaaggta agattagtat tggcaaagat tgtatgctgg cacatggata tgaaattaga
    21181 aatactgata tgcatccaat ttattcttta gaaaatggcg aacgaataaa ccatggtaaa
    21241 gacgttatta tcggtaatca cgtgtggctt ggccgcaatg ttactatatt aaaaggtgta
    21301 tgtattccaa ataatgtagt tgtaggttct catactgtgc tatataaaag ttttaaagaa
    21361 cctaattgtg taatagcagg ttcacctgca aaaatagtaa aagaaaatat tgtatgggga
    21421 agaaaaatgt atcattcaac tatgtatgat gaccctactt taaatgaatt ttataaataa
//
LOCUS       DAXISH010000035        21195 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.035, whole genome shotgun sequence.
ACCESSION   DAXISH010000035 DAXISH010000000
VERSION     DAXISH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 21195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21195
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.035"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(1..262)
                     /locus_tag="ACFOV4_001269"
                     /pseudo
     CDS             complement(1..262)
                     /locus_tag="ACFOV4_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981065.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
     gene            complement(291..620)
                     /locus_tag="ACFOV4_001270"
     CDS             complement(291..620)
                     /locus_tag="ACFOV4_001270"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFC7619277.1"
                     /translation="MGGLIIEDLQEGFGKEAVKGKEITVHYTGWLENGTKFDSSLDRR
                     QPLTITLGVGQVIKGWDEGFGGMKEGGKRKLAIPSEMGYGAHGAGGVIPPHATLIFEV
                     ELLKVYE"
     gene            complement(698..916)
                     /locus_tag="ACFOV4_001271"
     CDS             complement(698..916)
                     /locus_tag="ACFOV4_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2061 domain-containing protein"
                     /protein_id="HFC7619278.1"
                     /translation="MLKTLTFAALHFSTAFSVTYVLTGSIGVSGAVALVEPLINTVVF
                     YFHEKAWNLYEKNKTVQQTQPFQLHRCS"
     gene            1038..1991
                     /locus_tag="ACFOV4_001272"
     CDS             1038..1991
                     /locus_tag="ACFOV4_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HFC7619279.1"
                     /translation="MNHKKIVVLDADTLPGRVFHFDFPHELAVYGTTGADETAERVRD
                     AHIIITNKVMISADIIAHAPQLELIAVSATGVNNVDIEAAKAAGVAVCNVRAYGNESV
                     AEHAFMLMIALMRNLPAYQRDVAAGLWEKSPFFCHYGAPIRDLNGKTLAVFGRGNIGR
                     TLARYAQAFGMRVVFAEHKHAPVVREGYVSFEDAVQTADVLSLHCPLNAQTENMIGEN
                     ELQQMKPGAVLINCGRGGLVDENALVAALKYGQIGGAGVDVLTEEPPRGGNPLLNARL
                     PNLIVTPHTAWASREALDRLFDILLANIHAFVKGEAQNRVV"
     gene            complement(2066..4123)
                     /gene="metG"
                     /locus_tag="ACFOV4_001273"
     CDS             complement(2066..4123)
                     /gene="metG"
                     /locus_tag="ACFOV4_001273"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFC7619280.1"
                     /translation="MTRKILVTSALPYANGSIHLGHMVEHIQTDVWVRFQKLRGHECY
                     YCCADDTHGTPVMLAAQKQGIAPEDMIAKVREEHLADFTGFNIGYDNYYSTHSPENKQ
                     FSQDIYRALKANGKIESRVIEQLFDPEKQMFLPDRFVKGECPKCHAQDQYGDNCEVCG
                     TTYSPTELINPYSAVSGAKPELRESEHFFFKLDECADFLKAWTSGNNPHDGKPHLQPE
                     ALNKMKEWLGEGEETTLSDWDISRDAPYFGFEIPDAPGKYFYVWLDAPVGYMASFKNL
                     CDRIGVDFDEYFKADSQTEMYHFIGKDILYFHALFWPAMLHFSGHRAPTGVYAHGFLT
                     VDGQKMSKSRGTFITAKSYLEQGLNPEWMRYYIAAKLNSKIEDIDLNLQDFISRVNSD
                     LVGKYVNIAARASGFIAKRFEGRLKDVSGSALLAKLAAESDTIAEQYENREYARALRD
                     IMALADIVNEYVDANKPWELAKQEGQDERLHEVCSELINAFTMLTAYLAPILPKVAEN
                     AAKFLNLEAITWANTRETLGEHAINKYEHLMQRVEQKQVDDLIEANKQSIAAAAAPAA
                     EESQYEKVAEQASFDDFMKIDMRVAKVLNCEAVEGSTKLLKFDLDFGFEKRIIFSGIA
                     ASYLNPAELNGRMVIAVANFAPRKMAKFGVSEGMILSAATADGKLKLLDVDAGAQPGD
                     KVG"
     gene            complement(4238..6076)
                     /gene="glmS"
                     /locus_tag="ACFOV4_001274"
     CDS             complement(4238..6076)
                     /gene="glmS"
                     /locus_tag="ACFOV4_001274"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFC7619281.1"
                     /translation="MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIK
                     RVRRVGRVQLMEDAAREKGISGGIGIGHTRWATHGGVTEPNAHPHISGGMIAVVHNGI
                     IENFESERKRLEGLGYRFESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYA
                     IAVIAQDKPDELVVARMGCPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLA
                     SDGIKRLTDKNGLPAERKVKVSELSLASLELGPYSHFMQKEIHEQPRAIADTAEVFLD
                     GGFIPENFGKNAKSVFESIRSVKILACGTSYYAALTAKYWLESIAKIPTDVEIASEYR
                     YRSVIADPDQLVITISQSGETLDTMEALKYAKSLGHRHSLSICNVMESALPRESSLVL
                     YTRAGAEIGVASTKAFTTQLVALFGLAVTLAKVRGLVSGEDEARYTEELRQLPGSVQH
                     ALNLEPQIAAWAQQFAKKTSALFLGRGIHYPIALEGALKLKEITYIHAEAYPAGELKH
                     GPLALVDENMPVVVIAPNDSLLDKVKANMQEVGARGGELFVFADLDSNFNATEGVHVI
                     RAPRHVGKLSPVVHTIPVQLLAYHTALARGTDVDKPRNLAKSVTVE"
     gene            6358..6876
                     /locus_tag="ACFOV4_001275"
     CDS             6358..6876
                     /locus_tag="ACFOV4_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619282.1"
                     /translation="MKQMLLAVGVVAVLAGCGKDAGGYEGYWREKSDKKEGMIAVKKE
                     KGNYFLNKINVFTGKEESMLLSEKDGALSINTGIGEIPIKLSDDGKELYVERRQYVKT
                     DAAMKDKIIAHQKKCGQTAQAYLDARNALPSNQTYQQHQAAIEQLKRRFEAEFDELEK
                     EIKCNGKPTLLF"
     gene            complement(7126..7188)
                     /locus_tag="ACFOV4_001276"
                     /pseudo
     CDS             complement(7126..7188)
                     /locus_tag="ACFOV4_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7294..8619)
                     /locus_tag="ACFOV4_001277"
     CDS             complement(7294..8619)
                     /locus_tag="ACFOV4_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HFC7619283.1"
                     /translation="MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPV
                     GIPAPAGTTVAGGGAVYTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCA
                     QAFQTPVHSFQAKQFFERYFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIY
                     GIPDDFISVPLPAGLRSGKALVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIK
                     GRFEGSRFLPYHTRNQINGGALDGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIR
                     IGYADKNEHPYVSIGRYMADKGYLKLGQTSMQGIKAYMQQNPQRLAEVLGQNPSYIFF
                     RELTGSSNDGPVGALGTPLMGEYAGAVDRHYITLGAPLFVATAHPVTRKALNRLIMAQ
                     DTGSAIKGAVRVDYFWGYGDEAGELAGKQKTTGYVWQLLPNGMKPEYRP"
     gene            8831..9670
                     /gene="efeU"
                     /locus_tag="ACFOV4_001278"
     CDS             8831..9670
                     /gene="efeU"
                     /locus_tag="ACFOV4_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033573 - high-affinity iron permease
                     complex [Evidence IEA];
                     GO_function: GO:0005381 - iron ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034755 - iron ion transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake transporter permease EfeU"
                     /protein_id="HFC7619284.1"
                     /translation="MLVAFLIMLREGIEAALIVGIVAGFLKQSGHSKLMPKVWFGVVL
                     ASLMCLGIGYGIHSATGEIPQKQQEFVVGIIGLVAVAMLTYMILWMKKAARSMKQQLQ
                     DSVQAALNRGSGQGWALVGMAFLAVAREGLESVFFLLAVFKQSPTWQMPAGAVAGVLA
                     AAVIGALIYQGGMRLNLAKFFRWTGAFLIVVAAGLLAGSLRALHEAGIWNALQDIVFD
                     SSKYLHEDSPLGVLLGGFFGYTDHPTQGEALVWLLYLIPVMTWFLCGSRPSETLTRKE
                     ELK"
     gene            9667..10833
                     /gene="efeO"
                     /locus_tag="ACFOV4_001279"
     CDS             9667..10833
                     /gene="efeO"
                     /locus_tag="ACFOV4_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HFC7619285.1"
                     /translation="MRKFNLTALSVMLALGLTACQPPEAEKAAPAASGEAQTANEGGS
                     VSIAVNDNACEPMELTVPSGQVVFNIKNNSGRKLEWEILKGVMVVDERENIAPGLSDK
                     MTVTLLPGEYEMTCGLLTNPRGKLVVTDSGFKDTANEADLEKLSQPLADYKAYVQGEV
                     KELVAKTKTFTEAVKAGDIEKAKSLFADTRIHYERIEPIAELFSELDPVIDAREDDFK
                     DGAKDAGFTGFHRIEYALWVEKDVSGVKEIAAKLMTDVEALQKEIDALAFPPGKVVGG
                     ASELIEEVAGSKISGEEDRYSHTDLSDFQANVDGSKKIVDLFRPLIEAKNKALLEKTD
                     TNFKQVNEILAKYRTKDGFETYDKLGEADRKALQASINALAEDLAQLRGILGLK"
     gene            11097..12362
                     /gene="efeB"
                     /locus_tag="ACFOV4_001280"
     CDS             11097..12362
                     /gene="efeB"
                     /locus_tag="ACFOV4_001280"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0033212 - iron import into cell [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake transporter
                     deferrochelatase/peroxidase subunit"
                     /protein_id="HFC7619286.1"
                     /translation="MSKNQPAQPTRRTLFKTAIAAGAVGAIGGYLGGKKRGETAERTA
                     ESQHSPQAYPCYGEHQAGIVTPQQAFSIMCAFDVTAQSAKQLENLFRTLTARIEFLTQ
                     GGEYQDGDDKLPPAGSGILGKAFNPDGLTVTVGVGSSLFDGRFGLKDKKPIHLQEMRD
                     FSNDKLQKSWCDGDLSLQICAFTPETCQAALRDIIKHTVQTAVIRWSIDGWQPKSEPG
                     AMAARNLLGFRDGTGNPKVSDPKTADEVLWTGVAANSLDEPEWAKNGSYQAVRLIRHF
                     VEFWDRTPLQEQTDIFGRRKYSGAPMDGKKEADQPDFAKDPEGNTTPKDSHIRLANPR
                     DPEFLKKHRLFRRAYSYSRGLASSGQLDVGLVFVCYQANLADGFIFVQNLLNGEPLEE
                     YISPFGGGYFFVLPGVEKGGFLGQGLLGV"
     gene            complement(12434..12763)
                     /locus_tag="ACFOV4_001281"
     CDS             complement(12434..12763)
                     /locus_tag="ACFOV4_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFC7619287.1"
                     /translation="MSLPPCPQCASEYTYEDGGQYICPECAHEWNETESAADLAAQVL
                     DANGAVLQNGDTVILIKDLKVKGSSMVIKQGTKVKGIRLQEGDHNIGCKIDGSAMNLK
                     SEFVKKA"
     gene            complement(12840..14210)
                     /gene="glmU"
                     /locus_tag="ACFOV4_001282"
     CDS             complement(12840..14210)
                     /gene="glmU"
                     /locus_tag="ACFOV4_001282"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFC7619288.1"
                     /translation="MPQNTLNIVILAAGKGTRMYSKMPKVLHRIGGKPMLGRVIDTAA
                     ALNPQNICVVIGHGKDQVLNAVKRDVVWVEQTEQLGTGHAVKTALPHLAAEGRTLVLY
                     GDVPLIDVETLETLLEAAGNEVGLLTDVPADPSGLGRIIRDGSGSVTAIVEEKDADAA
                     QKAVKEINTGILVLPNAKLENWLNSLSSNNAQGEYYLTDLIAKAVADGIKVHPVQVRA
                     SHLAAGVNNKRQLAELERIFQTEQAQELLKAGVTLRDPARFDLRGRLKHGQDVVIDVN
                     CIFEGEVELGDNVEIGANCVIKNAKIGANSKIAPFSHLESCEVGENNRIGPYARLRPQ
                     AKLAADVHVGNFVEIKNAAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANYDGVHKH
                     KTVIGDEVRIGSNCVLVAPVTLGNKVTTGAGSTITRNIEDNKLALARARQTVIEGWMR
                     PEKDKQ"
     gene            complement(14265..14537)
                     /locus_tag="ACFOV4_001283"
     CDS             complement(14265..14537)
                     /locus_tag="ACFOV4_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex protein"
                     /protein_id="HFC7619289.1"
                     /translation="MRKTFLILMTAAALLSGCAWETYQDGNGKTAVRQKYPAGTPIYY
                     QDGSYSKNMNYNQYRPERHAVLPNQTGNNADEEHRQHWQKPKFQNR"
     gene            complement(14513..15244)
                     /locus_tag="ACFOV4_001284"
     CDS             complement(14513..15244)
                     /locus_tag="ACFOV4_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HFC7619290.1"
                     /translation="MQENPTVWLFDLDNTLHNADAGLFTLINRAMTRYMTRRLKLSES
                     AASDLRQDYWHRYGATLAGLQIHHPEIDIAEFLRESHPIDEVLTRLHGMPETQNTLSR
                     LKGRKAVFSNGPSFYVRAVVGALGLENRFDALFGTDDFGLLYKPNPQAYLNVCRLLDV
                     PPECCIMVDDSADNLHQAKALGMKTVRFGAKVHDLPFIDASVSDMAQLARYAETLSEH
                     RQNHYNTRTTPRKYERMLCVKPSLS"
     gene            15303..16304
                     /locus_tag="ACFOV4_001285"
     CDS             15303..16304
                     /locus_tag="ACFOV4_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7619291.1"
                     /translation="MKRKIWLLPLLAVSAYLQAQTEVRLAVHKSFSLPKGLIARFERA
                     NDAKVSIIQAGGANEMLNKLILSRANPIADAVYGLDNANIGKAREMGILAAAQPESAP
                     VAVGLPSALAVDYGYVSINYDKKWFEGKKLPLPQTLQDLTRPEYKNLLVVPSPATSSP
                     GLGFLMANISGLGEEGAFKWWAQMRQNGVKVAKGWSEAYYTDFSHNGGAYPLVVGYAA
                     SPAAEVYFSKGKYSEPPTGNLFLKGGVFRQVEGAAVLKGAKQPELAAKLVQWLQSREV
                     QQAVPSEMWVYPAVKNTRLPDVFRFAQAPTHTTAPAQRDIDANQRGWVSRWIRTVLK"
     gene            16398..17246
                     /locus_tag="ACFOV4_001286"
     CDS             16398..17246
                     /locus_tag="ACFOV4_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFC7619292.1"
                     /translation="MDFKQFDFLHLISVSGWEHLAEKAWAFGLNLAAALLIFLVGKWA
                     AKRIVAVMRAAMTRAQVDATLISFLCNVANIGLLILVIIAALGRLGVSTTSVTALIGG
                     AGLAVALSLKDQLSNFAAGALIILFRPFKVGDFIRVGGFEGYVREIKMVQTSLRTTDN
                     EEVVLPNSVVMGNSIVNRSTLPLCRAQVIVGVDYNCDLKVAKEAVLKAAVEHPLSVQN
                     EERQAAAYITALGDNAIEITLWAWANEADRWTLQCDLNEQVVENLRKVNINIPFPQRD
                     IHIINS"
     gene            17272..17757
                     /locus_tag="ACFOV4_001287"
     CDS             17272..17757
                     /locus_tag="ACFOV4_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CinA family protein"
                     /protein_id="HFC7619293.1"
                     /translation="MDALHTIARNLTKKRQTVSCAESCTGGMLAAAFTSVAGSSQWFD
                     QSFVTYSNKAKEDRLGVLPETLLEHGAVSRQTVYEMARGAKAVAQADYAVGISGIAGP
                     GGGSESKPVGTVWFGFAFPGGSCEAMRRFDGNRESVRAQAVAFALERLAGLIENGGDA
                     V"
     gene            complement(17859..19427)
                     /gene="msrAB"
                     /locus_tag="ACFOV4_001288"
     CDS             complement(17859..19427)
                     /gene="msrAB"
                     /locus_tag="ACFOV4_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional peptide-methionine (S)-S-oxide
                     reductase MsrA/peptide-methionine (R)-S-oxide reductase
                     MsrB"
                     /protein_id="HFC7619294.1"
                     /translation="MKHRTFFSLCAKFGCLLALGACSPKIVDAGAATVPHTLSTLKTA
                     DNRPASVYLKKDKPTLIKFWASWCPLCLSELGQTEKWAQDAKFSSANLITVASPGFLH
                     EKKDGDFQKWYAGLNYPKLPVVTDNGGTIAQSLNISVYPSWALIGKDGDVQRIVKGSI
                     NEAQALALIRDPNADLGSLKHSFYKPDTQKKDSKIMNTRTIYLAGGCFWGLEAYFQRI
                     DGVVDAVSGYANGNTKNPSYEDVSYRHTGHAETVKVTYDADKLSLDDILQYFFRVVDP
                     TSLNKQGNDTGTQYRSGVYYTDPAEKAVIAAALKREQQKYQLPLVVENEPLKNFYDAE
                     EYHQDYLIKNPNGYCHIDIRKADEPLPGKTKAAPQGKGFDAATYKKPSDAELKRTLTE
                     EQYQVTQNSATEYAFSHEYDHLFKPGIYVDVVSGEPLFSSADKYDSGCGWPSFTRPID
                     AKSVTEHDDFSYNMRRTEVRSHAADSHLGHVFPDGPRDKGGLRYCINGASLKFIPLEQ
                     MDAAGYGALKSKVK"
     gene            19572..20837
                     /gene="ftsY"
                     /locus_tag="ACFOV4_001289"
     CDS             19572..20837
                     /gene="ftsY"
                     /locus_tag="ACFOV4_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFC7619295.1"
                     /translation="MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVE
                     SLTESVKGQVESAVETVSGAVEQVKEAVAEMLSEAEEAAEKAAEQVEAAKEAIAETVG
                     EAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
                     VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPET
                     KEPFVIMLAGINGAGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNN
                     VTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKA
                     MPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRP
                     VPVRYIGVGEGIDDLRPFDARAFVDALLD"
BASE COUNT         4536 a         5298 c         6334 g         5027 t
ORIGIN      
        1 acgaagtttt tcggccatgt gccgtgattc gggcaatact cgggtggttt gtgcaaccgg
       61 cagttgattc atcgcggcag gttgacggca ggtgcttggg gtcgatctgc ttgtcgctgg
      121 cggcggtaac ggcggtgtcg gtgtcggtgt cggcgcgcgt aaccggctgt ccgcagaacc
      181 attttaccga accgtcttga cgcttggccc acagggagag ttttttgtct ttgatttcgt
      241 tgtttacgcc gcttgaagcc attatgtcag acggtattgc ccgggcagct ttattcgtac
      301 actttcagca gctcgacttc aaatatcaaa gtggcgtgcg ggggaatcac gccgcccgcg
      361 ccgtgtgcgc cgtagcccat ttccgaaggg atggccagct tgcgtttgcc gccttccttc
      421 atgccgccga agccttcgtc ccagcctttg atgacttgtc cgacaccgag cgtgatggtc
      481 agcggctggc ggcggtcgag gctggagtcg aatttggttc cgttttccag ccaacctgtg
      541 taatgcacgg taatctcttt gcctttaact gcttcttttc cgaagccttc ttgcaagtct
      601 tcaataatca ggccgcccat atttgtcctt tcgttgcttg ttggtcaaaa cggcaagggt
      661 aacataccgt ccgtcgaagt caaatgccgc tcaaacgtca gctgcatcgg tgcagctgaa
      721 acggctgtgt ttgttggact gttttatttt tttcgtaaag gttccatgct ttttcatgga
      781 aatagaaaac gacggtgttg attaggggct cgaccagcgc gaccgccccc gatacgccta
      841 tactgcccgt cagtacatag gttacactga aggcggtgct gaaatgcagt gcggcaaaag
      901 tcagggtttt aagcatcatc ctctcccgaa ttggacattg acggaggaat gataaaggtt
      961 atcataaggt tgcgcggttt aaatttgcta tttgttgtta gtgtaaataa atcatttttc
     1021 aaatggggat agaaattatg aatcataaaa agatcgttgt tttggatgcg gatactttac
     1081 ccggccgggt ttttcatttt gattttccgc acgagcttgc ggtttacggt acgacaggtg
     1141 cggatgaaac ggcagaacgg gtgcgcgacg cgcatattat catcaccaat aaagtgatga
     1201 tttcagcgga tatcattgca cacgctccgc aacttgaatt gattgccgtc agtgcgaccg
     1261 gtgtgaacaa tgtcgatatt gaggcggcga aggcggcggg cgttgcggta tgcaatgtcc
     1321 gcgcctacgg aaacgaatcg gttgcggaac acgcctttat gctgatgatt gcgttaatgc
     1381 ggaatttgcc cgcctatcag cgtgatgttg cggcaggatt atgggaaaag tcgccgtttt
     1441 tctgccatta tggcgcgccg attcgggatt tgaacggtaa aacgctggcg gttttcggac
     1501 gcggcaatat aggacggacg cttgcccgat atgcacaggc attcggtatg agggtagtgt
     1561 ttgccgaaca caaacacgcg cccgttgtgc gtgaaggcta tgtttccttt gaagatgcgg
     1621 tacagactgc cgacgtgttg tcgctgcact gtccgctgaa cgcccaaact gaaaatatga
     1681 taggcgaaaa cgaattacag cagatgaagc ccggtgcggt tttgatcaat tgcgggcgcg
     1741 gtgggctggt ggatgaaaat gcgctggttg ccgcactcaa atacgggcag attggcgggg
     1801 caggtgtcga tgttttgacg gaggaaccgc ctaggggcgg caatcccttg ctgaatgcac
     1861 gacttcccaa tctgattgtt acgccgcata ccgcgtgggc aagtcgtgaa gcgttggaca
     1921 ggctgttcga tatattgttg gcgaacattc acgcctttgt gaaaggcgag gcgcaaaacc
     1981 gcgtggtttg aacctgtcgg gattgcggaa aaaaatgccg tctgaacgcc tcaagggttc
     2041 agacggcatt ttttgagatt tctgcttaac cgactttgtc gcccggttgc gcgcctgcat
     2101 ccacatccaa gagcttcagt ttcccgtctg ccgtggcggc agagagaatc atgccttcgg
     2161 atacgccgaa ttttgccatt ttgcgcgggg cgaagttggc gacggcgatg accatccttc
     2221 cgtttaactc ggcagggttc aggtaagacg cggcgatgcc ggagaagatg atgcgttttt
     2281 caaaaccgaa atcgaggtcg aatttcaaaa gtttggtgct gccttcgaca gcttcgcagt
     2341 tcaatacttt ggcaacgcgc atatcgattt tcataaagtc gtcgaagctt gcctgttcgg
     2401 caactttttc gtattgactt tcttcggcgg caggtgcggc tgcggcggcg atgctttgtt
     2461 tgttggcttc gattaaatcg tccacttgtt tttgctccac tcgttgcatg agatgttcgt
     2521 atttgttgat ggcgtgttcg cccaaggttt cgcgtgtgtt tgcccaagtg atggcttcca
     2581 aattcaggaa tttggcggcg ttttcggcca ctttcggcaa gatgggggca aggtaggcgg
     2641 tcagcatggt aaaggcgttg atgagttcgc tgcatacttc gtgcaggcgt tcgtcttggc
     2701 cttcttgttt cgccagttcc caaggtttgt tggcatcgac gtattcgttg acaatgtctg
     2761 ccaaggccat gatgtcgcgc agggcgcggg cgtattcgcg gttttcgtat tgctcggcga
     2821 tggtgtcgct ttcggcggca agttttgcca gcaatgcgct gcctgaaacg tctttcagac
     2881 ggccttcaaa gcgtttggcg atgaaacctg atgcgcgggc ggcgatgttg acgtatttgc
     2941 cgacgaggtc gctgtttacg cgcgaaataa agtcttgcag gttcaaatcg atgtcttcga
     3001 ttttgctgtt gagttttgcg gcgatgtagt agcgcatcca ctcggggttc aggccttgtt
     3061 ccaaataaga tttggcagtg atgaaggtgc cgcgcgattt ggacattttt tgtccgtcta
     3121 cggtcaaaaa gccgtgtgcg tacacgccgg tcggggcgcg gtggccggag aaatgcagca
     3181 tggcaggcca gaacagggcg tggaaataga ggatgtcttt gccgatgaag tggtacatct
     3241 cggtttggct gtcggctttg aagtattcgt caaaatcgac gccgatgcgg tcgcacaggt
     3301 ttttaaacga cgccatgtag ccgacgggcg cgtccagcca gacgtagaag tatttgcccg
     3361 gcgcgtcggg gatttcaaaa ccgaaatacg gtgcgtcgcg ggaaatgtcc cagtcggaca
     3421 gggtggtttc ttcgccttcg cccagccatt ctttcatttt gttgagggct tcgggttgca
     3481 gatggggctt gccgtcgtgc ggattgttgc cggaagtcca tgctttgagg aagtcggcgc
     3541 attcgtccag tttgaagaag aagtgttcgg attcgcgcaa ttcgggtttg gcaccggaaa
     3601 cggcggaata cggattaatc agttcggtcg gggaataggt cgtgccgcag acttcgcagt
     3661 tgtcgccgta ttggtcttgg gcgtggcatt tcgggcattc gcctttaacg aaacggtcgg
     3721 gcaggaacat ttgtttttca gggtcgaaaa gctgctcgat gacgcggctt tcgattttgc
     3781 cgttggcttt cagcgcgcgg taaatgtctt gggaaaactg tttgttttca ggggaatggg
     3841 tgctgtaata attgtcgtag ccgatgttga aaccggtaaa gtcggcgagg tgctcttcgc
     3901 gcactttggc aatcatgtct tcgggcgcga tgccttgttt ttgcgcggca agcatcacgg
     3961 gcgtgccgtg ggtgtcgtcg gcgcagcagt agtagcattc gtggccgcgc agtttttgga
     4021 agcgcaccca aacgtcggtt tggatgtgtt cgaccatgtg gccgaggtgg atgctgccgt
     4081 tggcataggg cagggcggag gtaactaaga ttttgcgtgt catattgtgc tttgcaaaca
     4141 atgggtaaag gcggattata ccgcaaatca aacggggaaa tgccgtctga agcctgaaaa
     4201 atcgggcttc agacggcatt ttgccaatcg gcgggattta ttcgacggtt acggatttcg
     4261 ccagattgcg cggcttgtcc acatccgtgc cgcgtgcgag ggcggtgtgg taggcgagga
     4321 gctgcacggg gatagtatgc acgacggggg acagtttgcc gacgtggcgc ggtgcgcgga
     4381 taacgtgcac accttcggtg gcattaaaat tgctgtcgag gtcggcaaag acgaaaagtt
     4441 cgccgccgcg cgcgccgact tcctgcatat tggctttgac tttgtccaac aggctgtcgt
     4501 tgggtgcgat gacgacgacg ggcatgtttt cgtccaccaa ggcaagcggc ccgtgcttca
     4561 gttcgccggc aggataggct tcggcgtgga tgtaggtgat ttccttcagt tttaacgcgc
     4621 cttcgagggc aatcgggtaa tggatgccgc gccccaaaaa cagcgcgctg gttttcttgg
     4681 caaactgttg cgcccaagcg gcaatttgcg gttcgaggtt taaagcgtgc tgcacgctgc
     4741 cgggaagctg gcggagttct tcggtataac gtgcttcatc ttcgccggat accaagccgc
     4801 gtaccttcgc cagcgttacc gccaaaccga acagtgcgac cagctgcgtg gtaaatgctt
     4861 tggtcgaggc gacgccgatt tccgcaccgg cacgggtata aagcacgagg ctgctttcgc
     4921 gcggcagggc ggattccatc acgttgcaaa tggagaggct gtggcggtgt cccaaagatt
     4981 tggcgtattt caaagcctcc atcgtgtcca gcgtttcgcc ggattgggaa atggtaatga
     5041 ccagttggtc cggatcggca atcacgctgc ggtatcggta ttcgctggcg atttcgacgt
     5101 cggtcggaat tttggcgatg gattcgagcc agtatttggc ggtcagcgcg gcgtaatagg
     5161 acgtgccgca ggcaaggatt ttgacgctgc ggatgctttc aaacacgctt ttggcgtttt
     5221 tgccgaagtt ttcggggatg aagccgccgt cgaggaaaac ctccgccgtg tctgcaatcg
     5281 cgcggggctg ctcgtggatt tccttttgca taaagtggct gtacggcccc agctccaaag
     5341 aggcgagcga gagttcggat accttgactt tgcgttcggc aggcaggccg tttttatcgg
     5401 tcagcctttt gatgccgtct gaagccagca gtgcgatgtc gccgtcttca aggtacgcca
     5461 cgcggcgcgt aaaggcgatg acggcggaca cgtccgaagc gataaaggtt tcatcgtcgc
     5521 ccaaagcgac caaaagcggg cagcccatac gcgccacaac taattcatca ggcttgtctt
     5581 gggcaataac cgcgatggcg tatgcgccgt ggaaacgttt gaccgcttcc tgcacggctt
     5641 caaacagcct gccgccgttt tgcgcgtatt cgtgattgat gctgtgggcg atgacttcgg
     5701 tatccgtttg cgattcaaac cggtatccca aaccttccaa gcgtttgcgt tcgctttcaa
     5761 agttttcgat gatgccgttg tggacgacgg ctatcatccc accggaaata tgcggatggg
     5821 cattcggctc ggtaacgccg ccgtgtgtcg cccaacgcgt atgcccgatg ccgatgccgc
     5881 cgctgatgcc tttttcgcgt gctgcgtctt ccataagctg cacgcgtccg acgcggcgca
     5941 cgcgtttgat tttgccgtcg gtgttgacgg caatgcctga tgagtcataa ccccggtatt
     6001 cgaggcgttt gaggccgtcg gtcagaaaat cgacgacgtt gtgatgggcg cggatggcgc
     6061 cgacgatacc gcacataact gttccttagt atccggttga aaaaaaacag gcgcggacgg
     6121 ctcccgtgcc gcaccttcct cttcggatta taaaccgcct cccgcgccga aaaacagcaa
     6181 aatgccgtct gaaggcttgg gcttgctcaa aaaagggagg gatttccccg cctgaccggg
     6241 atgggcgttc agacggcatt gcctgccgcc ggtttatagt ttttacaaat caatattgac
     6301 aagctgaaaa aaaaaaacaa tatactcgct cggtcttaat gttaacggag tatggaaatg
     6361 aaacaaatgc ttttagccgt cggcgtggtg gcggtgttgg cgggctgcgg caaggatgcc
     6421 ggcggttacg agggttattg gcgcgaaaaa tcggacaaaa aagagggtat gattgccgtc
     6481 aaaaaagaaa aaggcaatta cttccttaat aaaatcaacg tgtttacagg taaggaagaa
     6541 tctatgcttt tgtctgaaaa agacggcgcg ctttcgataa acacggggat aggggaaatc
     6601 ccgatcaaac tttccgatga cgggaaagag ctgtatgtcg aacgcaggca gtatgtcaaa
     6661 accgatgcgg cgatgaagga caaaatcatc gcccatcaga aaaagtgcgg acaaacggca
     6721 caggcatatc tcgacgcgcg aaatgcgttg ccgtcaaacc agacgtatca gcagcatcag
     6781 gcggcgatcg agcagttgaa acggcggttt gaagccgagt ttgacgaatt ggaaaaagaa
     6841 atcaaatgca acggcaaacc gacattgttg ttttagcgta ggacaaccgg gaggatgccg
     6901 ccgtccgaat cggacgtgcg gtttctgtac cggtacgggc gggcaggaat gtccgctttt
     6961 tttgttcgga cgcgtttgaa tacccgtttg attccgtccg tttgcaaagg gtatttttgt
     7021 tcgggcggaa attatagtgg attaacaaaa accagtacag cgttgcctcg ccttagctca
     7081 aagagaacga ttctctaagg tgctcaagca ccaagtgaat cggttccgta ctatttgtac
     7141 tgtctgcggc ttcgtcgcct tgtcctgatt taaatttgat ccactataat tccgtcaaat
     7201 aagaaaggaa ttttgtgcct gcggtatcgc aaaacttcgc cttaatgcgc ccgattgcct
     7261 agggatgggc ttcagacggc attgttttcc ggtttacggg cggtattcgg gcttcatacc
     7321 gttgggcaga agctgccaga catatcccgt ggttttctgt ttgccggcaa gttcgccggc
     7381 ttcgtcgccg taaccccaaa aataatccac gcgcaccgcg cctttaatcg cgctgccggt
     7441 atcctgcgcc ataatcaggc ggttgagggc tttgcgggta accggatggg cggtggcgac
     7501 aaataagggc gcgcccaagg taatgtagtg ccggtcgact gcgccggcgt actcgcccat
     7561 cagcggcgtg cccagtgcgc cgacagggcc gtcattgctg cttccggtaa gctctcggaa
     7621 aaagatatag ctggggtttt gccccaaaac ttcggcgagg cgttgcgggt tttgctgcat
     7681 ataggctttg atgccctgca tcgaggtctg cccgagcttg aggtagcctt tgtccgccat
     7741 atagcgtccg atggaaacgt agggatgttc gtttttgtcg gcatagccga tgcggatgta
     7801 tttgccggac ggggttttca gacggcccga gccttggatg tgcataaaaa aaagttcgac
     7861 ggggtcttcg gcgtaaccga gtatcggggc tttgccgtca agcgcgccgc cgttgatttg
     7921 gttgcgcgtg tggtagggga ggaagcggct tccttcaaac ctgcctttga ttgccgttgt
     7981 gcgcgcggtg atggggaatc gggagaggtc ggcggtgtgc gtgccgccgg cattgtcgat
     8041 tgtgccgctg tttttccccg tctgcctgat gcggacaagg gcttttccgc tccgcaaacc
     8101 ggcaggcagg gggacggaga taaaatcgtc gggaataccg taaatcggga agcgggcttg
     8161 tgccgtccgc ctgtcgtcgc ccttcagcac cggctcgtaa tagccggtaa ccgtaccggc
     8221 aaggcttccg ttgcctgcaa cctgccacgg cgtgaaatag cgttcaaaaa actgttttgc
     8281 ctgaaaggaa tggacggggg tttgaaaggc ttgggcacac acatcctgcc agccttggcg
     8341 gtttttcaaa ttggcgcagc cgaggcggaa ggattgcagg cttttggcga aatcctgcgc
     8401 cgcccagtgg ggcagggaca ggtgcggcac aacggtataa acggccccgc cgccggcaac
     8461 cgtcgttccg gcgggggcgg ggatgccgac cggccggtcc gggccgttga tgacggatgt
     8521 gtcgggttgc ggaaaggttt ggatgctctt gctttggcag gcggcgagga tggcggcggc
     8581 gatgccgcac agggcggcgc ggaacaggta ttttttcata atggacaatg ttgtcagcag
     8641 taataaaaaa agatggtttc gggcggcgtt gcggcagccg tggagagggg attttaacac
     8701 agggcgcagc tgcagcctgc ggaactttcc gccgcgcggt actgcagata aaaataactt
     8761 gcatttgtat ttacaagcaa tgaaaatatt ccgataatat attattcatc atccttgttc
     8821 gttcgcgttt atgctggtcg cttttttaat tatgttgcgc gagggtatcg aagccgcgct
     8881 catcgtcggc atcgttgccg gttttctgaa acagtccgga cattccaaac tgatgcctaa
     8941 ggtctggttc ggggtcgtcc ttgcttcttt gatgtgtttg ggcatcggat acggcatcca
     9001 ttcggcaacg ggcgagattc cccagaagca gcaggagttc gtcgtcggca ttatcggttt
     9061 ggttgctgtc gcgatgctga cttatatgat tttatggatg aaaaaggcgg cgcgttcgat
     9121 gaagcagcag cttcaggatt ctgtacaggc ggctttgaac cgtggcagcg gtcaaggatg
     9181 ggccttggtc ggtatggcgt ttcttgccgt ggcgcgtgaa ggtctggaga gtgttttttt
     9241 cctgcttgcc gtattcaaac agagcccgac ttggcagatg ccggccggcg cggtagcggg
     9301 ggttttggct gccgccgtga ttggcgcgtt gatttatcag ggtgggatgc gcctgaatct
     9361 ggcgaagttt ttccgttgga cgggggcgtt tctgattgtc gttgccgccg gcctgcttgc
     9421 cggttcgctg cgcgcgctgc atgaggcagg tatttggaac gcgcttcagg acattgtgtt
     9481 cgactcatca aaatatttgc acgaagacag cccgttgggc gtgctgctcg gcggattttt
     9541 cggctatacc gaccatccga cgcagggcga agccttggtt tggctgctgt accttattcc
     9601 cgtcatgact tggtttttgt gcggcagcag gccgtctgaa actttaaccc gtaaagagga
     9661 gctgaaatga gaaaattcaa tttgaccgca ttgtccgtga tgcttgcctt aggtttgacc
     9721 gcgtgccagc cgccggaggc ggagaaagct gcgccggcag cgtccggtga ggcgcaaacc
     9781 gccaacgagg gcggttcggt cagtatcgcc gtcaacgaca atgcctgcga accgatggaa
     9841 ctgaccgtgc cgagcggaca ggttgtgttc aatattaaaa acaacagcgg ccgcaagctc
     9901 gaatgggaaa tcctgaaagg cgtgatggtg gtggacgagc gcgaaaacat cgcccccgga
     9961 ctttccgata aaatgaccgt caccctgttg ccgggcgaat acgaaatgac ttgcggtctt
    10021 ttgaccaatc cgcgcggcaa gctggtggta accgacagcg gctttaaaga caccgccaac
    10081 gaagcggatt tggaaaaact gtcccaaccg ctcgccgact ataaagccta cgttcaaggc
    10141 gaggttaaag agctggtggc gaaaaccaaa acctttaccg aagccgtcaa agcaggcgac
    10201 attgaaaagg cgaaatccct gtttgccgac acccgcatcc attacgaacg catcgaaccg
    10261 attgccgagc ttttcagcga actcgacccc gtcatcgatg cgcgtgaaga cgacttcaaa
    10321 gacggcgcga aagatgccgg atttaccggc ttccatcgta tcgaatacgc cctttgggtg
    10381 gaaaaagacg tgtccggcgt gaaggaaatt gcagcgaaac tgatgaccga tgtcgaagcc
    10441 ctgcaaaaag aaatcgacgc attggcgttt cctccgggca aggtggtcgg cggcgcgtcc
    10501 gaactgattg aagaagtggc gggcagtaaa atcagcggcg aagaagaccg gtacagccac
    10561 accgatttga gcgatttcca agccaatgtg gacggttcga aaaaaatcgt cgatttgttc
    10621 cgtccgctga tcgaggccaa aaacaaagcc ttgttggaaa aaaccgatac caacttcaaa
    10681 caggtcaacg aaattctggc gaaataccgg actaaagacg gttttgaaac ctacgacaag
    10741 ctgggcgaag ccgaccgcaa agcgttacag gcctctatta acgcgcttgc cgaagacctt
    10801 gcccaacttc gcggcatact cggcttgaaa taagccgcaa gcgttcagac ggtatttggc
    10861 ggcagatacc gtctgaagtt ttatagtgga ttaacaaaaa ccagtacggc attgcctcgc
    10921 cttgccttgc cgtactattt atactgtctg cggcttcgtc gccttgtcct gatttttgtt
    10981 aatccactat atccgccata tattgcaggg cgggatttca acctgccgct atcggttaat
    11041 ggaaaaacgg cgtgcaggga tacccatcct gctgcacgga tattgaagga aacaccatga
    11101 gcaaaaacca acccgcacaa ccgaccaggc gcactctttt taaaaccgcg atcgcagccg
    11161 gagcagtcgg cgcaatcgga ggttatctcg gcggcaaaaa acggggcgaa accgccgaac
    11221 gcaccgccga aagtcaacac tcgccccaag cctatccctg ctacggcgaa catcaggcag
    11281 gcatcgttac gccgcagcag gcgttttcga ttatgtgcgc cttcgacgta accgcgcaaa
    11341 gtgccaagca gctggaaaac ctgttccgca cgctgaccgc ccgcatcgag tttctcaccc
    11401 aaggcggcga ataccaagac ggcgacgaca aacttccgcc agccggcagc ggcattttgg
    11461 gcaaagcctt caaccccgac gggttgaccg ttaccgtggg ggtgggcagc agcctgtttg
    11521 acggccggtt cggactcaaa gacaaaaaac cgattcattt gcaggaaatg cgcgacttct
    11581 ccaacgataa gctgcaaaaa agctggtgcg acggcgattt gagcctgcaa atctgtgcct
    11641 tcacccccga aacctgccaa gccgccctgc gcgacatcat caaacacacc gtccaaaccg
    11701 ccgttatccg ctggagtatc gacgggtggc agcctaaatc cgaacccggc gcgatggcgg
    11761 cgcgcaacct gttgggcttc cgcgacggca cgggcaaccc caaagtttcc gaccccaaaa
    11821 ccgccgacga ggttttgtgg acgggtgtgg ccgccaacag cctcgacgaa ccggagtggg
    11881 cgaaaaacgg cagctatcag gcagtccgcc ttatccgcca ctttgtcgag ttttgggaca
    11941 ggacgccgct tcaagagcaa accgacattt tcgggcggcg caaatacagc ggtgcgccga
    12001 tggacggcaa aaaagaagcc gaccaaccgg attttgccaa agaccccgag gggaatacca
    12061 cgcccaaaga cagccatata cgcctggcga atccgcgcga tcccgaattc ctcaaaaaac
    12121 accgcctctt ccgccgcgcc tacagctatt cgcgcggact cgcctcaagc ggacagcttg
    12181 atgtcgggct ggtgttcgtc tgctatcagg caaaccttgc cgacggattc atcttcgtgc
    12241 aaaacctcct caacggcgaa ccgctggaag aatacatcag ccccttcggc ggcggctatt
    12301 tcttcgtctt gcccggcgtg gaaaaaggcg gctttttggg gcaagggctg ctgggcgtat
    12361 aaatccgcca tataaaaaac gccgtccgaa ccttgccaaa cgggttcgga cggcgtttct
    12421 tgtttttggg cggtcaggct tttttgacga attcggattt taaattcatc gcgctgccgt
    12481 cgattttgca gccgatgttg tgatcgcctt cttgcaggcg tatgcctttg acttttgtgc
    12541 cttgtttgat caccatcgag ctgcctttta ccttgaggtc tttgatgagg atgacggtat
    12601 cgccgttttg cagcactgcg ccgttggcat cgagcacttg agccgcaagg tcggcggcgg
    12661 attcggtttc attccattcg tgggcgcatt cggggcagat gtattgtccg ccgtcttcat
    12721 aagtgtattc ggaggcgcat tgtgggcatg ggggtaatga catggtttgc agtccttatc
    12781 tgatatcgga ggagtttgat gccgtctgaa acctgaaacc ggcttcagac ggcatagctt
    12841 tattgcttgt ctttttcagg ccgcatccag ccttcgatga cggtttggcg ggcgcgggcg
    12901 agggcgagtt tgttgtcttc gatattgcgg gtaatcgtgc tgcctgcgcc tgtggttact
    12961 ttgttgccga gggtaacggg ggcgactagg acgcagtttg aaccgatgcg gacttcgtcg
    13021 ccgataacgg ttttgtgttt gtgcacaccg tcgtagttgg caataatcgt acctgcgccg
    13081 aagttggttt tgctgccgac ttcggcatca ccaatgtagg tgaggtggtt ggctttggtg
    13141 cctttgccga tggcggcgtt tttgatttcg acgaagttgc cgacgtgtac gtcggcggct
    13201 agtttggctt gcggacgcag gcgggcatag gggccgattc ggttgttttc gccgacttcg
    13261 cagctttcga ggtgggagaa gggggcgatt ttgctgtttg cgccgatttt ggcgtttttg
    13321 atgacgcagt ttgcgccgat ttcgacgttg tcgccgagtt cgacttcgcc ttcaaagata
    13381 cagttcacat caattacgac atcctgtccg tgtttcagac ggcctcgtaa atcgaaacgt
    13441 gccggatcgc gcagggttac gcctgctttg agcaattctt gcgcctgttc ggtttggaag
    13501 atgcgttcga gttcggcgag ctggcgtttg ttgttcacgc cggcggcgag gtgggaggcg
    13561 cggacttgga cgggatgaac tttaataccg tcggcaacgg ctttggcaat gaggtcggtt
    13621 aaataatatt cgccttgagc attgttgctg gagaggctgt tcagccagtt ttccagtttg
    13681 gcgttgggca gaaccaaaat gccggtattg atttctttca cggctttttg ggcggcgtcg
    13741 gcgtcttttt cttcgacaat ggcggttacg ctgccgctgc cgtcgcggat gatgcgcccc
    13801 aaacctgacg ggtcggcggg cacgtcggtc aacagcccga cttcgttgcc tgcggcttcg
    13861 agcagggttt cgagggtttc aacgtcaatt aaaggaacgt cgccgtacaa caccagcgtg
    13921 cggccttcgg cggcaaggtg gggcagggcg gttttgacgg cgtggccggt accgagctgt
    13981 tcggtttgtt caacccaaac gacatcgcgt ttgacagcgt ttaaaacttg gtctttgccg
    14041 tgcccgatga cgacgcagat gttttgcgga ttcagcgcgg cggcggtgtc gataacgcgc
    14101 ccgagcatgg gcttgccgcc gatgcggtgc agcactttgg gcattttgga atacatgcgc
    14161 gtgcctttgc cggcggcgag gataacgatg tttaaagtgt tttgcggcat gacggtttcc
    14221 tgtgcaatgc cgtctgaaag ggcttcagac ggcatagggt gggtttatcg gttttgaaat
    14281 ttgggctttt gccagtgttg gcgatgctct tcgtcggcgt tgttgccggt ttggttgggt
    14341 aacacggcat ggcgttcggg acggtattgg ttgtagttca tatttttcga gtagctgccg
    14401 tcttggtaat aaatgggcgt gccggcggga tatttttgac ggacggcggt cttgccgttg
    14461 ccgtcttgat aagtttccca cgcgcagccc gacaaaaggg cggcggcagt catcaggata
    14521 aggaaggttt tacgcataac attctttcgt attttcgggg ggttgtgcgg gtattgtaat
    14581 gattttggcg gtgttctgac aaagtttctg cataccgagc cagttgcgcc atatcgctta
    14641 cggaagcatc gataaagggc aggtcgtgca cttttgcacc gaaccggacg gttttcatgc
    14701 ccaatgcttt tgcctgatgc aggttgtccg cgctgtcgtc caccataatg cagcattcgg
    14761 gcggtacgtc caacaggcgg cagacattga gatacgcttg cggattgggt ttgtacagca
    14821 gcccgaaatc atccgtgccg aaaagcgcgt cgaaacggtt ttccaaaccg agtgcgccga
    14881 caacggcacg gacgtaaaac gacgggccgt tggaaaaaac cgccttgcgc ccttttaggc
    14941 ggctcagggt gttttgtgtt tccggcatac cgtgcagacg ggtcaaaacc tcgtcaatcg
    15001 gatggctttc gcgcaaaaat tcggcgatgt cgatttcggg atggtggatt tgcagtccgg
    15061 cgagcgttgc gccgtagcgg tgccaatagt cttgacgcag gtcggacgcg gcggattcgg
    15121 agagtttgag gcggcgtgtc atatagcgtg tcatagcgcg gttgatgagt gtgaagaggc
    15181 cggcatcggc attgtgcagc gtgttgtcga ggtcgaacag ccacacggtc gggttttctt
    15241 gcattttgaa ccgtgaaaat ttgttagaat gttattttac agcgaataga ggaggactcg
    15301 gaatgaaacg gaaaatttgg ctgctgccgc tgctggcggt ttcggcatac ctgcaggcgc
    15361 agacggaagt caggctggcg gtgcataagt cgttcagcct gcccaaaggg ctgattgcgc
    15421 gcttcgagcg ggcaaacgat gcgaaggtgt cgattattca ggcgggcggc gcgaacgaaa
    15481 tgctcaacaa actgattttg agccgcgcca acccgattgc cgacgcggtg tacggtttgg
    15541 acaacgccaa tatcggcaag gcgcgggaaa tgggcatttt ggcggcggcg caacccgaat
    15601 ccgcccccgt cgcggtcggg ctgccttcgg ctttggcggt cgattacggc tatgtgtcca
    15661 tcaattacga caaaaaatgg tttgaaggca aaaagctgcc cctgccgcaa accctgcagg
    15721 atttgacccg ccccgaatat aaaaacctat tggtcgtgcc gtcccccgcc acgtcgtccc
    15781 cggggctggg cttcctgatg gcgaacatca gcggtctggg cgaagaaggc gcgttcaaat
    15841 ggtgggcaca gatgcggcag aacggcgtga aggtcgccaa aggctggagc gaggcgtatt
    15901 acaccgactt ttcgcacaac ggcggcgcgt atccgctggt ggtcggttat gccgccagcc
    15961 cggcggcgga agtgtatttt tccaaaggca aatacagcga gccgccgacg ggcaacctgt
    16021 ttttaaaagg cggcgtattc cgccaggtcg aaggcgcggc ggtcttgaag ggcgcgaaac
    16081 agccggaatt ggcggcaaaa ctggtgcaat ggctgcaaag tcgggaagtg cagcaggcgg
    16141 ttccgtccga aatgtgggtt taccccgccg tcaaaaacac gcgcctgccc gacgtgttcc
    16201 gcttcgccca agccccgacg cacaccaccg cccccgcgca gcgcgatatt gatgcgaacc
    16261 agcgcggatg ggtttcccgt tggattagaa cggttttgaa ataaaacaaa cataccgccc
    16321 cgcagggctt catacggcat ttttacacct gtgccgatta cgccgcacgg ggcggatgtt
    16381 cgatcaagag gaaaacaatg gacttcaaac aatttgattt tttacacctg atcagtgttt
    16441 ccggttggga gcatctggct gaaaaggcgt gggcgttcgg gctgaacctt gccgccgcgc
    16501 tgcttatttt tttggtcgga aaatgggcgg cgaaacgcat tgtcgctgtg atgagggcgg
    16561 cgatgacgcg cgcgcaggtc gatgccacgc tgattagttt tttgtgtaat gttgccaata
    16621 tcggcttatt gattttggtg attattgccg cattgggcag attgggcgtt tccacaacat
    16681 ccgtaaccgc cttaatcggc ggcgcgggtt tggcggtggc gttgtccttg aaagaccagc
    16741 tgtccaattt tgccgccggc gcgctgatta tcctgttccg cccgttcaaa gtcggcgatt
    16801 ttatccgcgt cggcggtttt gaaggatatg tccgagagat taaaatggtg cagacttctt
    16861 tgcggacgac cgacaacgaa gaagtcgtgc tgcccaacag cgtggtgatg ggcaacagca
    16921 tcgtcaaccg ttccacactg ccgctgtgcc gcgcccaagt gatagtcggc gtcgattaca
    16981 actgcgattt gaaagtggcg aaagaggcgg tgttgaaagc cgccgtcgaa caccccttga
    17041 gcgttcaaaa cgaagagcgg caggccgccg cctacatcac cgccttgggc gacaatgcca
    17101 tcgaaatcac attatgggct tgggcaaacg aagcagaccg ctggacgctg caatgcgact
    17161 tgaacgaaca agtggtcgaa aacctccgca aagtcaatat caacatcccg ttcccgcaac
    17221 gcgacataca catcatcaat tcttaaacgc cgtctgaaag gggagtggga aatggacgcg
    17281 ctgcacacca tcgcccgaaa cctgacgaaa aaacgtcaaa ccgtaagctg tgccgaatcc
    17341 tgtacgggcg gaatgcttgc cgccgcattc acaagcgttg caggcagttc gcaatggttc
    17401 gatcaaagtt ttgtaacata cagcaacaaa gccaaagaag accgcttggg cgtgttgccc
    17461 gaaaccctgc tcgaacacgg cgcggtcagc cgccaaaccg tctatgagat ggcgcgcggc
    17521 gcgaaagccg tggcgcaggc ggattacgcc gtcggtattt ccggcatcgc cggaccgggc
    17581 ggcggcagcg aaagcaaacc cgtcggcacg gtttggttcg ggtttgcctt tccgggcgga
    17641 agttgcgaag caatgcgccg ttttgacggc aaccgcgaat ccgtccgcgc gcaggcggtc
    17701 gccttcgcgt tggaacggtt ggcggggctg attgaaaacg gcggcgatgc cgtctaaaca
    17761 aaatctccgt ctggacaaaa tccccgccgg ataaaaaata ccgtctgaaa cgttgcaggt
    17821 ttcagacggt attttgtcgg gttaggcggc ggtgcggctt atttcacttt actcttcaac
    17881 gcgccgtagc ctgccgcgtc catttgttcc agcgggatga atttcaagct cgcgccgttg
    17941 atgcagtagc gcagtccgcc tttgtcgcgc gggccgtcgg ggaagacgtg tcccaaatgc
    18001 gaatcggcgg cgtggctgcg cacttcggtg cggcgcatgt tgtagctgaa atcatcgtgt
    18061 tcggtaacgg attttgcatc aatcgggcgc gtgaagctcg gccagccgca gccggaatca
    18121 tatttgtcgg cggagctgaa caaaggttcg ccgctgacaa cgtccacata aatgccgggt
    18181 ttgaacaaat ggtcgtattc gtggctgaag gcgtattcgg tcgcgctgtt ttgggtcact
    18241 tggtattgct cttcggtcag ggtgcgtttg agttcggcat cactgggttt tttatacgtt
    18301 gccgcatcga agcctttgcc ttgcggggcg gctttggttt tgcccggcag tggttcgtcg
    18361 gctttgcgga tatcgatgtg gcagtagccg ttggggtttt taatcaggta gtcctgatgg
    18421 tattcctcgg catcgtagaa gtttttcagc ggctcgtttt caacaacgag gggcagttgg
    18481 tatttttgct gctcgcgttt gagggcggcg gcgatgacgg ctttttcggc ggggtcggtg
    18541 tagtacacgc cgctgcggta ttgcgtaccg gtgtcgttgc cctgtttgtt gaggctggtc
    18601 ggatcaacga cgcggaagaa atattgcagg atgtcgtcta ggctgagttt gtcggcatcg
    18661 taggtcactt taacggtttc ggcgtggccc gtatggcggt aggacacgtc ttcatagctc
    18721 ggatttttcg tgttgccgtt ggcgtagccg gataccgcgt caaccacgcc gtcgatgcgt
    18781 tggaaatagg cttccaagcc ccagaagcag ccgccggcga ggtaaatggt gcgcgtgttc
    18841 atgatttttg aatccttttt ctgagtgtcg ggtttgtaga acgaatgttt caagctgccc
    18901 aaatcggcat tcgggtcgcg gattaacgcc aacgcctgcg cttcgttgat gctgcctttg
    18961 acgatgcgct gcacgtcgcc gtctttaccg attaacgccc acgaggggta aacgctgata
    19021 ttcaggcttt gggcgatcgt gccgccgttg tcggttacga cgggcagctt gggataattc
    19081 aaaccggcat accatttttg gaagtcgccg tcttttttct cgtgcaaaaa gcccggagac
    19141 gcgacggtaa tcaggttggc ggagctgaat tttgcatctt gcgcccattt ttcggtctgt
    19201 cccaattcgg acagacacaa aggacaccag ctcgcccaaa atttaatcag cgtcggtttg
    19261 tcttttttca agtaaacact ggcggggcgg ttgtccgcag ttttcaaagt ggataaagtg
    19321 tgcggcacgg tcgcggctcc ggcatcgacg attttgggcg aacaagcacc cagcgcaagc
    19381 aggcagccga acttggcgca aagggaaaag aaagtacggt gtttcatttt gagtttcctg
    19441 tgtggacggt ttgcatgatt agacgtttga gatgccgaaa ccttacagct cggattttca
    19501 gacaaccttg ccgcgtaaaa tacgctacaa tacgccctgt ttcaagtttc taaaattaaa
    19561 aggaaaattc aatgttcagc ttcttccgtc gcaagaaaaa acaggaaacg ccggctcccg
    19621 aggaggctca agttcaggaa actgcagcaa aagcagaatc cgaagttact caaatagttg
    19681 aaaatattaa agaagaagtc gaatctttaa cggaaagcgt caaagggcag gtcgaatcgg
    19741 ctgttgaaac cgtcagcggt gcggttgaac aagtaaagga agccgttgcc gagatgctgt
    19801 ctgaagcaga ggaagcggcg gaaaaagcag cggaacaagt cgaagcggca aaagaagcca
    19861 ttgccgaaac cgtcggcgag gctgtcgggc aagttcaaga agccgttgca acaactgaag
    19921 aacacaagct cggttgggcg gcgcgtttga aacaaggttt gaccaaatcg cgcgacaaaa
    19981 tggcgaaatc gctggcgggc gtgttcggcg gcggacaaat cgacgaagat ttgtacgaag
    20041 agctggaaac cgtgctgatt accagcgata tgggcatgga agccaccgaa tacctgatga
    20101 aagacgtgcg cgaccgcgtc agcctcaaag ggctgaaaga cggcaacgaa ttgcgcggcg
    20161 cgctgaaaga agccttgtac gacctgatta agcctctaga gaaaccgctg gttttgcccg
    20221 aaaccaaaga gccgtttgtc atcatgcttg ctggcatcaa cggcgcgggc aaaaccacat
    20281 ccatcggcaa actcgccaaa tatttccaag cgcagggcaa atctgtgctg cttgccgccg
    20341 gcgatacttt ccgcgccgcc gcgcgtgagc agcttcaagc ttggggcgaa cgcaacaacg
    20401 taaccgtgat ttcgcaaacc acgggcgatt ccgccgccgt gtgcttcgat gccgtccaag
    20461 ccgccaaagc gcgcggcatc gacattgtgc tggccgacac cgccggccgc ctgcccacgc
    20521 agcttcactt gatggaagaa atcaaaaaag tgaaacgcgt gctgcaaaaa gccatgcccg
    20581 acgcgccgca cgaaatcatc gtcgtgcttg atgccaacat cgggcaaaac gccgtcaacc
    20641 aagtcaaagc ctttgacgac gcattagggc tgaccggttt aatcgtgacc aaactcgacg
    20701 gcacggcaaa aggcggcatc ctcgccgcgc ttgcctccga ccgccccgtc cccgtccgct
    20761 acatcggcgt gggcgaaggc atagacgatt tgcgcccgtt tgacgcgcgc gcgtttgtgg
    20821 acgcactgct ggattgagcc gaaatgccgt ccgaaaacag cagaccgatg ccgtcattcc
    20881 cgcgcaggcg ggaatccaga ccttgggata acggcaatat tcaaagttta taaaagaccc
    20941 gtcattcccg cgcaggcggg aatctagacc ttgggataac agcaatattc aaaggttagc
    21001 tgaagcttta gagattctgg attcccactt tcgtgggaat gacgggattt gagattgcga
    21061 catttatcgg gagcaacaga aaccgctctg ccgtcattcc cgcgcaggcg ggaatctaga
    21121 ccttagaaca acagcaatat tcaaagatta tctgaaagtc cgggattctg gattcccact
    21181 tccgtgggaa tgacg
//
LOCUS       DAXISH010000036        20969 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.036, whole genome shotgun sequence.
ACCESSION   DAXISH010000036 DAXISH010000000
VERSION     DAXISH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 20969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20969
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.036"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..563
                     /locus_tag="ACFOV4_001290"
     CDS             <1..563
                     /locus_tag="ACFOV4_001290"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC7619296.1"
                     /translation="RKTEKECAVLGTLSRLDTVRAVHLMLDILKKMVDRGMPVRLNIA
                     GIGEEMDNLKAQAERLGIDGKVTFLGGIRDLTAYFKDVDILVNTPHCIGDHGAGVGNN
                     ILEAGLYDTPVVTYDMAGISEMVVNGETGYCIPFGDEEAFIAAVDTLVRQPELREAMG
                     KRLHAHVAALCSDDEIYRTTMAAYTM"
     gene            583..1750
                     /locus_tag="ACFOV4_001291"
                     /pseudo
     CDS             583..1750
                     /locus_tag="ACFOV4_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981110.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            1743..2270
                     /locus_tag="ACFOV4_001292"
                     /pseudo
     CDS             1743..2270
                     /locus_tag="ACFOV4_001292"
                     /inference="COORDINATES: protein motif:HMM:NF014453.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
     gene            2319..3320
                     /locus_tag="ACFOV4_001293"
     CDS             2319..3320
                     /locus_tag="ACFOV4_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFC7619297.1"
                     /translation="MPYFTGNQTNEKNNILILSAGRRVELVQDFQTEAARFSDGISVF
                     ATDLNPRMSSACHVSDGSFEVPPISADSYIDSIFNLAVRENIGLIIPTIDTELQKLAD
                     ERERFEAASVHIVVSDSDFIAQCRDKRKTATLFARYGIRSPEIYDRKKLVFPCFAKPY
                     DGSRAIGAKRIDTPADLTPEVLADTKLMFCQFIDIENKFSEFTVDMYYDRQCRLKCAI
                     PRKRLEVRSGEISKGVTCKNSLYQTLLEKMSVLQGARGCITAQFFYNEETGEFYGVEI
                     NPRFGGGFPLTYAAGGNYPSRLMREYLGDEEIPFSDDWENNLIMLRYDAKVLVHEND"
     gene            3307..3993
                     /locus_tag="ACFOV4_001294"
     CDS             3307..3993
                     /locus_tag="ACFOV4_001294"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFC7619298.1"
                     /translation="MKTINPETTVIVFDLDDTLYSEYEYKLSGIRSVIDTVAALYPDW
                     NSDNLWRNIDPDGKDWLDKLCRHCGFNESEKQVLLWQYRLHRPTLTPYAPPDFLSELT
                     APFAARALITDGRSLTQRLKLEALGLSSLFDDILISEACSSEKPDGKRFRHLQDKYAD
                     KAGCFIYIGDNISKDFIAPNTLGWITIGLLPSGQNIHRHQPESFNTEYHPDFWVNSLQ
                     DLVPIIDSNT"
     gene            4041..4235
                     /locus_tag="ACFOV4_001295"
     CDS             4041..4235
                     /locus_tag="ACFOV4_001295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619299.1"
                     /translation="MTKYYSWGVNGFPPYVFDTIWKRWKLNGRGGGYRVRHPGRHDRR
                     GQSGKAAAAQKPQDRDGISD"
     gene            4229..4345
                     /locus_tag="ACFOV4_001296"
                     /pseudo
     CDS             4229..4345
                     /locus_tag="ACFOV4_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4464..5639
                     /locus_tag="ACFOV4_001297"
     CDS             4464..5639
                     /locus_tag="ACFOV4_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HFC7619300.1"
                     /translation="MLNTSLSPWPCFTQEEADAVSKVLLSNKVNYWTGSECRKFEKEF
                     AAFAGTRYAVALSNGTLALDVALKAIGIGAGNDVIVTSRTFLASASCIVNAGANPVFA
                     DVDLNSQNISAETIKAALTSNTKAIIVVHLAGMPAEMDGIMDLAKEHDLWVIEDCAQA
                     HGAKYKGKSVGSIGHVGAWSFCQDKIMTTGGEGGMVTTNDKTLWEKMWSYKDHGKSYD
                     AVYHREHAPGFRWLHESFGTNWRMMEMQAAIGRIQLKRLPEWTACRQAHAAKLAESLG
                     KFKSIRLVEVADYIGHAQYKFYAFVKPEHLKDGWTRDRIVSELNARKVPCYQGSCSEV
                     YLEKSFDDTPWRPKERLKNAVELGDTSLMFLVHPTLTDDEIAFCKEHIEAVLAEATR"
     gene            5687..7597
                     /gene="pglD"
                     /locus_tag="ACFOV4_001298"
     CDS             5687..7597
                     /gene="pglD"
                     /locus_tag="ACFOV4_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent dehydratase PglD"
                     /protein_id="HFC7619301.1"
                     /translation="MTLETLIALPRNIKKICFLIHDFLMIFIAFWFTQSLKADYSDEW
                     FDPANWQSFLLTAFLTACLFFRMGLYRAVTRFISFRILSTALAGSLASAVLFFLNTLI
                     FEERLRLALPIVYFLLLFVSVTGSRMVLRGLLSEHPKKQMAPVIIYGAGRSGRQLLKA
                     VKQMREYSAAAFVDDDPKLWHTVIYDLAVYQPDAIAFLIERYGVEKILLAIPGATQEQ
                     RRRIINKLEAYPCEVLTIPGMKDLMDGKISIGTLKKISVSDLLGRDSVAPDNRLMSAD
                     IEGKTVMVTGAGGSIGSELCRQIIRRRPEKLLLFELSEFALYAVEKELRETCIQKRLD
                     TEILPFLGSVQNRTLLEHVMTAFSVATVYHAAAYKHVPMVEFNTVEGIRNNIFGTLEC
                     ALAATTSGVETFVLISTDKAVRPTNTMGASKRMAELCLQALAAEPGQKTRFSMVRFGN
                     VLGSSGSVVPAFEKQIAEGGPITLTHQDITRYFMTIPEAAQLVIQAGAMGKGGDVFVL
                     DMGESVKIIDLARQMITLSGLKPKTPEQPDGDIEILITGLRPGEKLYEELLIGDNVRK
                     TGHPRIMTADEAMLPWHELSVLLDRIRAACDRYDQQAIRTLLINAPTGFTPSDGICDL
                     LWVRETHRKNAV"
     gene            7653..8945
                     /locus_tag="ACFOV4_001299"
     CDS             7653..8945
                     /locus_tag="ACFOV4_001299"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HFC7619302.1"
                     /translation="MQFSAFGEKFTQHSGILQLMDDLGDALKSDKPVNMLGGGNPARI
                     AEVNAVFADVFSKLAAEHAVENIGNYSNPQGDAALIDALTAFLNREYGWNLTADNIAL
                     TNGSQNAFFYLFNLFGGKFNLSDGTSAEKAILLPLAPEYIGYADVHVEGQHFVSVKPK
                     IENVEHEGEAGFFKYRVDFDALENLPELKAGKIGAICCSRPTNPTGNVLTDSEMARLD
                     ALAQEHGIPLIIDNAYGMPFPNIIYSDVTLNWHENIILCFSLSKVGLPGVRTGIIVAA
                     PEVVKAVSSLNAIVNLAPTRFGAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLL
                     KRELGAYPMKIHKPEGAIFLWLWFENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTR
                     DYPHAGECIRMSIAQDAQTLEKGIAAIGKTVRKLYDNV"
     gene            complement(8997..9833)
                     /locus_tag="ACFOV4_001300"
     CDS             complement(8997..9833)
                     /locus_tag="ACFOV4_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFC7619303.1"
                     /translation="MIDLHCHSTVSDGMLSPAEVVRLAHQNGCTLLALTDHDHTGGIA
                     EARAEADRLGLRLINGVEISVTWRGRTIHVVGLDFDEQDENLQNLLAQVRQGRLKRLE
                     AIAAKLEKRGISGAYDGALALAANKEMVSRTHVAEFLIRVGHVKNKQQAFTKYLGDGK
                     SCAVRHEWATLEDCVSAVNGAGGMAVIAHPMRYDLSATAKRNLFEEFKNLGGAGIEVH
                     SGNCCKNDRLNYAFLAERFGMLASAGSDFHRLNDFSGGILGACPELPENCRPVWAHFS
                     RH"
     gene            complement(10229..10432)
                     /locus_tag="ACFOV4_001301"
     CDS             complement(10229..10432)
                     /locus_tag="ACFOV4_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase-like domain-containing protein"
                     /protein_id="HFC7619304.1"
                     /translation="MDMTLKHKAEALLGEPLLDEPVRPESWECCGSDCGEACIQTIYW
                     ADKARYDAQRRKLKEAGWSDDAV"
     gene            complement(10410..10643)
                     /locus_tag="ACFOV4_001302"
     CDS             complement(10410..10643)
                     /locus_tag="ACFOV4_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFC7619305.1"
                     /translation="MEAIVYLEDNEYIALCDLLKLAGLAESGGQAKALIAEGLVSRNG
                     ETETCKTAKIRGGEVIEFDGARLEIADGYDPEA"
     gene            11181..14615
                     /gene="dnaE"
                     /locus_tag="ACFOV4_001303"
     CDS             11181..14615
                     /gene="dnaE"
                     /locus_tag="ACFOV4_001303"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFC7619306.1"
                     /translation="MTEPTYIPLRLHTEFSITDGMVRIKKLIAKAQEYGLPALGISDL
                     MNEFGLVKFYKACRSAGIKPVGAADVWIGNPNAPDKPFRAMLIIRNDAGYQRLSELLT
                     EAYVGKDRNVHHAELNPEWLENGDNSGLICLSGAHYGEVGMNLLNGNEDAARAAALKY
                     AAWFPDAFYLELQRLPERPEWEACVSGSVKLAEELGLPVVATHPTQFMNRDDFNAHEA
                     RVCIAGGWVLTDKKRPRDFTPDQFFIPPETMLERFADLPEALENTVEIAKRCNLHITL
                     GKNFLPLFPTPDGLSRDDYLIKLSNKGLQERMVQLYPDEAERAAKMPEYQERLDFELN
                     IIIQMKFPGYFLIVQDFINWAKTHGCPVGPGRGSGAGSLVAYSLKITDLDPLKYALLF
                     ERFLNPERVSMPDFDVDFCQANRGRVIEYVREKYGAEAVSQIVTFGTMSSKAVIRDVG
                     RVLELPFMLCDKLSKLIPLEANKPLGLDDAMKAEPQIQELIEAEEADELITLAKKLED
                     LTRGLGMHAGGVLIAPGKISDYSPVYQADESASPVSMYDKGDVEDVGLVKFDFLGLRN
                     LTIIEMAQNNIKNTTGDIIDVGKIPLDDQVAYQIFRDANTTAVFQFESTGMKKMLKTA
                     HTTKFEELIAFVSLYRPGPMDNIPDFVARMKGQEFQYIHPLLEGILAPTYGIMVYQEQ
                     VMQAAQIIGGYSLGGADLLRRAMGKKKPEEMVKHREIFAEGAAKQGISREKSDEIFNY
                     MEKFAGYGFNKSHAAAYALISYQTAWLKAHYPAEFMAATMSSELDNTDQLKHFYDDCR
                     ANGIEFLPPDINESDYRFTPYPDMKIRYALGAIKGTGEAAVESITAARQSGGKFTGLL
                     DFCERVGKEHMNRRTLEALIRGGAFDSIEPNRAMLLANIDLAMDNADQKAANANQGGL
                     FDMMEDAIEPVRLIDLPRWSESEKLAEEKTVIGFYLSGHPFGPYAQEVCQIAPTKLDR
                     LKPQDSVRLAGFVTAVRTMMGKRGKIAFVSLEDLSGQVEIMVGSQTLENCADCLKADQ
                     VLIIESKVSRDDYGGGDGLRIMANQVMTLQTARERYARSLSLALAPHHDIGGLVRLLS
                     SHQLPDTPRIPLQLSYANEKASGRLQVPPKWTVTPSSALFGELETLLGSRSVRVNW"
     gene            14893..18141
                     /gene="cas9"
                     /locus_tag="ACFOV4_001304"
                     /gene_synonym="csn1"
     CDS             14893..18141
                     /gene="cas9"
                     /locus_tag="ACFOV4_001304"
                     /gene_synonym="csn1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742773.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HFC7619307.1"
                     /translation="MAAFKPNPINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVR
                     VFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGL
                     IKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNEGETADKELGALLK
                     GVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRKDLQAELILLFEK
                     QKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAER
                     FIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKG
                     LRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSSELQDEIGTAFSLFKTD
                     EDITGRLKDRVQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYG
                     DHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETARE
                     VGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKC
                     LYSGKEINLVRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFN
                     GKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKECNLNDTRYVNRFLCQFVA
                     DHILLTGKGKRRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQK
                     ITRFVRYKEMNAFDGKTIDKETGKVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFE
                     EADTPEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRSAKRFVKHN
                     EKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEAYGGNAKQAFDPKDNPF
                     YKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADNGDMVRVDVFCKVDKKGKNQYFIVP
                     IYAWQVAENILPDIDCKGYRIDDSYTFCFSLHKYDLIAFQKDEKSKVEFAYYINCDSS
                     NGRFYLAWHDKGSKEQQFRISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR"
     gene            18207..19121
                     /gene="cas1"
                     /locus_tag="ACFOV4_001305"
     CDS             18207..19121
                     /gene="cas1"
                     /locus_tag="ACFOV4_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA];
                     GO_process: GO:0051607 - defense response to virus
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HFC7619308.1"
                     /translation="MTWRSLLIQNGGKLSLQRRQLLIQQNGESHTVPLEDIAVIIIEN
                     RETLITAPLLSALAEHGATLLTCDEQFLPCGQWLPYAQYHRQLKILKLQLNISEPLKK
                     QFWQHIVRQKILNQAFIADETGNDLAAKRLRTLASEVRSGDTGNREAQAAALYFQALF
                     GEKFTRNDNNAVNAALNYTYAVLRAAVARTLTLYGWLPALGLFHRSELNPFNLADDFI
                     EPLRPLADLTVIHLYEQGRLKAELTPGIKQHLIKTLHYQISIERQHFSTLAAIDKMVS
                     SFQAGVTDKNAKQLKLPEILPLKEYRYE"
     gene            19114..19440
                     /gene="cas2"
                     /locus_tag="ACFOV4_001306"
     CDS             19114..19440
                     /gene="cas2"
                     /locus_tag="ACFOV4_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HFC7619309.1"
                     /translation="MSEAKFMRIIVFFDLPVITAAKRKAANQFRQFLLKDGYQMLQLS
                     VYSRIVKGRDSLQKHHNRLCANLPQEGSIRCLEITEKQYAAMKLLLGELKTQEKKVNS
                     DQLLLF"
     repeat_region   19504..20595
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19504..19539
                     /rpt_unit_seq="attgtagcactgcgaaatgagaatgggagctacaac"
BASE COUNT         5519 a         5808 c         5134 g         4508 t
ORIGIN      
        1 tccggaaaac cgaaaaagaa tgcgccgtac tcggcacgct ttcccgtttg gacaccgtcc
       61 gcgccgtgca tctgatgttg gatattttga agaaaatggt tgaccgcggt atgcccgtcc
      121 gcctcaacat agcgggcata ggcgaagaaa tggacaattt gaaagcgcag gcggaacgtc
      181 tgggcataga cggcaaagtt accttcctcg gcggcatacg cgatttgacc gcctacttca
      241 aagacgtgga tattttggtg aacacgcccc actgcatcgg cgaccacggc gcaggtgtag
      301 gcaacaacat cttagaagcc ggactttacg acacgcccgt cgttacctac gatatggcgg
      361 gcatttccga aatggtcgtc aacggggaaa cgggttactg catccccttc ggcgacgaag
      421 aagcctttat cgccgccgta gacacgctcg tcagacaacc ggagttgcgc gaagcaatgg
      481 gcaaaaggct gcacgcacac gtcgccgcac tctgttccga cgacgaaatc taccgcacca
      541 ccatggcggc gtataccatg taatgccgtc tgaaagccgc cgatgaacat caccatagtc
      601 gccccttatt gctcgctgcc gtccgagccg cacttcaacc gctttcggta tcttgccgag
      661 ctgttgtcgc agtcgcatga cgtgctgctg attaccagca acttcaaaca ctacgacaaa
      721 tctttcagac ggcatgaaga tgccgaggcc gcctcgcaag gccgtctgaa agtcatgctg
      781 ttggaagaaa gcggctacgg caaaaacgtg tctttagaac gtgttgccag ccattaccgc
      841 ttcgtcaaaa attttgagca atggctgaaa aactgccggc cgggcgaaca agacatcgtc
      901 tattccgcct atccgctgat tgccaccaac ctgctgttgg gcaaacacaa agcgcgtttg
      961 ggctacaaac tgattgtcga cgtacaggac gtatggccgg agtctttctc ctcggtcgta
     1021 ccgtttttga aaaaagtacc gcacaagctg ctgccctttg cttcacgcgc caaccgtgcc
     1081 taccgctgcg ccgacgcgct ggttgccgta tcgcagactt atctcgaccg cgccaaagaa
     1141 gccaatccga acgtacccgg cgaagccgtc tatatcggta cggattttgc cgccatcgcc
     1201 cccccccccg cgattccgct ccaaaaccgt ccgccttttc tacttgggca cgctcagtta
     1261 cagctatgac gtggaaaccg tgtgcaaagg tgttcgcaag ctgttggacg acggcgaaaa
     1321 cgtcgaattg cacgttatgg gcggaggacc cgatttggag aaactcaaac aatatgaaaa
     1381 tcgcgccatc aagttttacg gttatttacc ctattctgaa atgatgtcga ttgccaaagc
     1441 gtgcgacatt gccgtcaacg ccatccatag ccacgccatg cagtcggtta ccaacaaact
     1501 ctccgactat atggccttgc aaaaaccgat tctgaacagc cagaccaatg ccgaagtcct
     1561 cgacctcatg aatctgctgc cacacgaaaa ctaccgttcc ggcgatgtgg acggtttcgt
     1621 tcaagccgcc aaaaatattt tgaaacgcaa aaacgattct gttcagtccg acgaaatcgt
     1681 ccgccgcttc aggcgcgatg ttgcctatca aaaaatcgtc aacctgattg aaagattagc
     1741 ccatgagtaa attcttcaaa cgcctgtttg acattgttgc ctccgcctcg ggactgattt
     1801 tcctctcgcc agtatttttg attttgatat acctcatccg caagaatctg ggttcgcccg
     1861 tgttcttcat ccaagagcgg ccgggcaagg acggcaagcc gtttaaaatg attaaattcc
     1921 gctctatgcg cgacgcgctt gattcagacg gcattccgct gcccgacgga gaacgcctga
     1981 caccgttcgg caaaaaactg cgtgccgcca gcttggacga actgcccgaa ctgtggaatg
     2041 tcttaaaagg cgagatgagc ctggtcggcc cgcgcccgct tttgacgggc tacctgccgc
     2101 tttataacga cttccaaaac cgccgccacg aaatgaaacc gggcattacc ggctgggcgc
     2161 aggtcaacgg gcgcaacgcg ctttcgtggg acgaaaagtt cgcctgcgat gtttggtaca
     2221 ccgacaactt cagcttttgg ctggatatga aaatcctgtt tttgacagtc aaaaaagtct
     2281 tgatcaaaga aggcatttcg gcggaagggg aagccactat gccttatttc actggaaatc
     2341 aaactaatga aaaaaataat atactgattc tgtcggcagg tcgccgtgtc gaattggtgc
     2401 aggacttcca aaccgaagcc gcacgttttt cagacggcat cagcgttttt gccactgacc
     2461 tcaacccccg catgtcttct gcctgccatg tttcggacgg ttcatttgaa gtgccgccga
     2521 ttagtgccga ttcatatatc gacagcattt tcaatctggc ggtacgcgaa aatatcggtt
     2581 taatcatccc aaccatagac accgaactgc aaaagctggc agacgagcgc gaacgctttg
     2641 aagcggcaag tgtccacatc gtcgtttccg attcggactt catcgcacaa tgccgcgaca
     2701 aacggaaaac cgccaccttg tttgcccgct acggcatacg ctcacccgaa atttacgacc
     2761 gcaagaagtt ggttttccct tgcttcgcca agccttatga cggcagccgc gccatcggtg
     2821 caaaacggat tgacacacct gccgacctga caccggaagt cttggcagac accaaattaa
     2881 tgttctgtca gtttatcgac atcgaaaata aattttccga gtttaccgtc gatatgtatt
     2941 acgaccgtca atgccgtctg aaatgcgcca tcccgcgaaa acgcttggaa gtgcgctccg
     3001 gcgaaatcag caaaggcgtt acctgcaaaa acagcctcta ccaaacgctg ctggaaaaaa
     3061 tgtcggtatt gcagggcgcg cgcggctgta tcacggcgca gttcttctac aacgaagaaa
     3121 ccggcgaatt ctacggcgtg gaaatcaacc cccgcttcgg cggtggcttc ccgctgacgt
     3181 atgccgcagg cggcaattat ccgagccggt tgatgcgcga atacctcggc gacgaagaaa
     3241 tcccgttttc agacgactgg gaaaacaacc tcattatgtt gcgctacgat gccaaggtct
     3301 tggttcatga aaacgattaa tcctgaaacc accgtcatcg tcttcgactt ggacgatacc
     3361 ctgtattcgg aatacgaata caagctctcc ggtatccgtt cggtcatcga taccgttgcc
     3421 gcactgtatc ccgattggaa ttcagacaac ctatggcgca acatcgaccc cgacggcaaa
     3481 gattggctgg acaaattgtg ccgccactgt ggttttaatg aatcggaaaa acaggttctt
     3541 ttgtggcaat accggctgca ccgcccgacg ctgactccgt atgctccgcc ggatttcctg
     3601 tccgaactga ccgcgccctt cgccgcacgc gcgctgatta ccgacggcag aagcctgacc
     3661 caacgcctga agctggaagc cttgggtctg tcttccctgt ttgacgacat cctcatctct
     3721 gaagcctgct cttcggaaaa gcccgacggc aaacgcttcc gccatcttca agacaaatat
     3781 gccgacaagg caggctgctt catctatatc ggcgacaaca tttccaaaga ctttatcgcg
     3841 ccgaacactt tgggctggat aaccatagga ttgcttccct ccggacagaa catccaccgc
     3901 caccagcctg aaagttttaa cacagaatat catcccgact tttgggttaa ctcccttcaa
     3961 gatttagttc ctataattga ttcaaatact taaccattac ataatcaaac atgcactcac
     4021 aatattaaaa ggactatttc atgacaaaat attattcatg gggcgtaaac ggctttccgc
     4081 cctacgtttt cgacaccatt tggaaacgat ggaagttgaa tgggcgcggg ggcggttatc
     4141 gtgtgcgaca tcccggacgg catgaccgtc gcgggcaatc cggcaaagcc gctgccgcgc
     4201 aaaaacccca agaccgggac ggcataagcg attaaaatat agtggattaa atttaaatca
     4261 ggacaaggcg acgaagccgc agacagtaca aatagtacgg caaggcgagg caacgccgta
     4321 ctggtttaaa tttaatccac tatacacccc cgtacagacc gattttgaca acacctgcgg
     4381 cgcgcgcccg attcttcgga acacgccccc cttcagacgg catagggtcg gaaatgccgt
     4441 ctgaacccga cggaccaaac accatgctga acacctccct ctccccgtgg ccctgcttta
     4501 cccaagaaga agccgatgcc gtttccaaag tcctgctgtc caacaaagtc aactactgga
     4561 cgggcagcga atgccgcaaa tttgaaaaag aatttgccgc ctttgccggc acgcggtacg
     4621 ccgtcgccct ttccaacggc acgctggcac tcgatgtcgc gctcaaagca atcggcatag
     4681 gcgcgggcaa cgatgtgatt gttacctcgc gcactttctt ggcttccgct tcctgcattg
     4741 tgaacgcggg cgcaaatccc gtgtttgccg atgtggattt gaacagccaa aacatcagcg
     4801 ccgaaactat caaagccgcg ctgacgtcga ataccaaagc catcatcgtc gtccacctcg
     4861 ccggtatgcc cgccgaaatg gacggcatca tggacttggc aaaagaacat gatttgtggg
     4921 tcatcgaaga ctgcgcccaa gcgcacggcg cgaaatacaa aggcaaatcc gtcggcagca
     4981 tcggacacgt cggcgcatgg tcgttctgcc aagacaaaat catgaccacg ggcggcgaag
     5041 gcggcatggt tacgaccaac gacaaaaccc tgtgggaaaa aatgtggtcg tacaaagacc
     5101 acggcaaaag ctacgatgcc gtgtaccacc gcgaacacgc gcccggtttc cgctggctgc
     5161 acgaaagttt cggcacaaac tggcgtatga tggaaatgca ggcggcaatc gggcgcatcc
     5221 agctcaaacg cctgcccgaa tggactgcct gccgtcaagc gcacgccgcc aagctggcgg
     5281 aaagcctagg caaattcaaa agtatccgct tggttgaagt cgccgactac atcggacacg
     5341 cgcaatataa gttctacgct ttcgtcaaac ccgaacacct caaagacggc tggacgcgcg
     5401 accgcatcgt cagcgaactg aacgcgcgca aagtcccctg ctatcaaggc agctgctccg
     5461 aagtctattt ggaaaaatct ttcgacgaca cgccttggcg gccgaaagag cgtttgaaaa
     5521 atgctgtcga actgggcgac accagcctga tgttcttggt gcacccgacg ctgaccgacg
     5581 acgaaatcgc gttctgcaaa gaacacatcg aagccgtatt ggcagaagcc acacgataac
     5641 cattcagacg gcatatgccg tctgaaaaat acacgccgcc gacaacatga ctctggaaac
     5701 cctgatcgcc ctgccgcgca acatcaagaa aatctgtttc ctcatacacg attttctgat
     5761 gattttcatt gccttttggt tcacccaaag cctaaaggcc gactactcgg acgaatggtt
     5821 cgaccccgcc aactggcagt ctttcctatt gaccgcgttt ttgaccgcct gcctgttctt
     5881 cagaatgggg ctttaccgcg ccgtcacacg cttcatcagc ttccgcatcc tctccaccgc
     5941 gctggcaggc agcctcgcct ccgccgtatt gtttttcctc aatacgctga tatttgaaga
     6001 acggctgcgg ctcgccctgc cgattgtcta tttcttactg ctgtttgttt ccgtgaccgg
     6061 ctcgcgtatg gttttgcgcg gactgttgtc cgaacacccc aaaaaacaga tggcccccgt
     6121 cattatttac ggcgcgggac ggtcgggcag acaactgctt aaggccgtca aacaaatgcg
     6181 cgaatattcc gccgccgcct ttgtggacga cgaccccaaa ctgtggcaca ccgtcatcta
     6241 cgaccttgcc gtttaccagc ccgatgccat cgccttcctc atcgaacgct acggcgtgga
     6301 aaaaatccta ctcgccatcc ccggcgcgac ccaggaacaa cgccgccgaa tcatcaacaa
     6361 actggaagcc tatccgtgcg aagtgttgac cattcccgga atgaaagacc tgatggacgg
     6421 gaaaatcagc atcggcacgc tcaaaaaaat ctctgtgtcc gacctgctcg ggcgtgattc
     6481 cgtcgcgccc gacaaccgcc tgatgagtgc cgacatcgaa ggcaaaaccg tcatggtaac
     6541 cggcgcgggc ggctccatcg gttcggaact ctgccgccag attatccgcc gccgccccga
     6601 aaagctgctg ctgttcgagt tatccgaatt cgccctgtac gccgtcgaaa aagaattgcg
     6661 cgaaacctgc atccaaaaac gcctcgacac cgaaatcctg ccctttctcg gttcggtgca
     6721 aaaccgcacg ctgctcgaac acgtcatgac cgccttttcc gttgcgaccg tctatcacgc
     6781 cgccgcctac aaacacgtcc ccatggtcga gttcaacacc gtcgaaggca tacgcaacaa
     6841 catcttcggc acactcgagt gcgcgcttgc cgccacgaca tcgggcgtgg aaactttcgt
     6901 cctcatctcc accgacaaag ccgtccgccc caccaacacc atgggtgcca gcaaacgcat
     6961 ggcggaactc tgccttcagg cgctcgccgc cgaacccgga caaaaaaccc gcttcagcat
     7021 ggtgcgtttc ggcaatgttt taggttcgtc cggctccgtc gtccccgcat ttgaaaaaca
     7081 aattgccgaa ggcggcccga ttaccctgac ccaccaagac attacccgct acttcatgac
     7141 cattcccgaa gcggcgcaac tggttatcca agccggcgcg atgggcaaag gcggcgacgt
     7201 attcgtcctc gatatgggcg aatccgtcaa aatcatcgac cttgcccgcc aaatgattac
     7261 cttaagcggc ctcaaaccca aaacacccga acaacccgac ggcgacatcg aaatcctcat
     7321 taccggactg cgtcccggcg aaaaactcta cgaagagctg ctcatcggcg acaacgtccg
     7381 caaaaccggc catccgcgca ttatgacggc tgacgaggcg atgctgccgt ggcacgagct
     7441 ctctgtcctg ctcgaccgca tccgtgcggc ctgcgaccgt tacgaccagc aggcaatccg
     7501 caccctgctc atcaacgccc cgaccggctt taccccaagc gacggtatct gcgacctgct
     7561 ttgggtacga gaaacacaca gaaaaaatgc cgtctgaacc ttcagacggc ataacgtaca
     7621 aaccaaccta ccttacacac acggagtttg acatgcagtt ctcagcattc ggcgaaaaat
     7681 tcacgcaaca cagcggcatc ctccaactga tggacgacct cggcgacgcg ctcaaaagcg
     7741 acaagcccgt caatatgctc ggcggcggca atccggcgcg aatcgccgaa gtcaatgccg
     7801 tgttcgccga cgtattttcc aaactggcag cagaacatgc cgtcgaaaac atcggcaact
     7861 actccaatcc tcaaggagat gccgcgctga ttgacgcgct gaccgccttc ctcaaccgcg
     7921 aatacggctg gaacctgacc gccgacaata tcgcgctgac caacggttcg caaaacgcgt
     7981 ttttctattt attcaacctc ttcggcggca aattcaacct ttcagacggc acatccgcag
     8041 aaaaagccat tttgttgccg ctcgcgcccg aatacatcgg ctatgccgac gtgcatgtcg
     8101 aagggcagca cttcgtttcc gtcaagccca aaatcgaaaa cgtcgaacac gaaggcgaag
     8161 caggcttctt caaataccgc gtggactttg acgcactgga aaacctgccc gaactcaaag
     8221 cgggcaaaat cggcgcgatt tgctgttcgc gcccgaccaa cccgaccggc aacgtgctga
     8281 ccgacagcga aatggcgcgg ctggacgctt tggcgcaaga acacggcatt ccgctgatta
     8341 tcgacaacgc ctacggaatg ccgttcccca acatcattta cagcgacgta acgctgaatt
     8401 ggcatgaaaa catcatcctc tgcttcagcc tttccaaagt cggtctgccg ggcgtgcgca
     8461 ccggcatcat cgtcgccgcg cccgaagtcg tcaaagccgt cagcagcctg aacgcgattg
     8521 tgaaccttgc ccccacgcgc ttcggcgcgg ccatcgccgc cccgctactg gaaagcggcg
     8581 agatgaaacg gcttgccgac caagtcatcc ggccgtttta ccgcaatcag gcgcaaaccg
     8641 ccgtctcgct gctcaagcgc gagctgggcg cgtacccgat gaaaatccac aaacccgaag
     8701 gcgcgatttt cctgtggctc tggtttgaaa acctgcccgt ttcttcgcaa accctgtacg
     8761 aaatgctcaa agccgaaggt acgctgatta ttccgggcga acatttcttc gtcggcatcg
     8821 acacgcggga ttatccgcac gcgggcgagt gcatccgtat gagcatcgcg caggacgctc
     8881 aaacgctgga aaaaggcatt gccgccatcg gtaaaaccgt ccgaaaactg tacgacaacg
     8941 tttaaaccgc aaaaaatgcc gtctgaaggc ctttcagacg gcatttttat ccgcattcaa
     9001 tgtcgggaaa aatgcgccca cactggcctg cagttttccg gcagttcggg acacgcgccg
     9061 aggatgccgc cgctgaagtc gtttaaacgg tggaagtcgc tgcccgcact ggcgagcatg
     9121 ccgaagcgtt ctgccaaaaa tgcgtagttg aggcggtcgt ttttgcagca gttgccgctg
     9181 tggacttcga tgcccgcgcc gccgaggttt ttaaattctt caaacagatt gcgcttggcg
     9241 gtagcggaca aatcatagcg catcggatgg gcgatgactg ccatgccgcc cgcgccgttg
     9301 acggcggaga cgcagtcttc cagcgtcgcc cattcgtgtc ggacggcgca ggatttgccg
     9361 tcgcccaagt atttggtgaa cgcctgctgc ttgtttttga cgtgtcccac ccgaatgagg
     9421 aactcggcga cgtgtgtgcg gctgaccatt tctttgtttg ccgccagcgc gagcgcgccg
     9481 tcgtatgcgc ccgaaatgcc gcgtttttcc agcttggcgg cgatggcttc gaggcgtttc
     9541 agacggcctt gccgcacttg cgccaacagg ttttgcaggt tttcgtcttg ttcgtcaaag
     9601 tctaagccga caacgtgtat ggtacgcccg cgccacgtta cggagatttc cacgccgtta
     9661 atcaggcgca aaccgagcct gtcggcttcg gcacgcgctt cggcgatgcc gccggtgtgg
     9721 tcgtggtcgg tcaacgccag cagcgtgcag ccgttttgat gcgcgaggcg cacaacttcg
     9781 gcgggggaga gcataccgtc ggaaacggtg gaatggcagt gcaggtctat cataaggcgt
     9841 tatgtgcgtg gtaaatggtg ggcagggtgt ttcaatattg tcgggcggtg tggcggcggt
     9901 gatttcaaaa aacaggtgta tggcaaatgc aaaggaaaag ccgctatgcc gtcattccag
     9961 cgcaggcggg aatccagact ttgatttatt ggaaatgttt aaggttaacc gctatttcaa
    10021 acttccggat tcctgctttc gagggaatgg cgatatgacc gttttcaatt ttaatctact
    10081 ataaaagact gtctgaaaac gtggttttat agtgaattaa atttaaaccg gtacagcgtt
    10141 ggctcgcctt gccgtactat ttgtactgtc tgcggctcgc cgccttgtcc tgatttttgt
    10201 taattcacta tatcaagccg aaccgttttc agacggcatc gtccgaccaa cccgcttctt
    10261 tcaatttccg ccgttgcgcg tcgtagcggg ccttatccgc ccaataaatc gtctgaatac
    10321 acgcctcgcc gcagtcgctg ccgcagcatt cccacgactc gggtcggacg ggttcgtcta
    10381 aaagcggctc gcccaaaagg gcttcggctt tatgcttcag ggtcatatcc atcggcgatt
    10441 tccaagcgcg caccgtcaaa ctcgatgact tcgccgccgc gtattttggc ggttttacag
    10501 gtttcggttt cgccgttgcg cgacaccaac ccttcggcaa tcaacgcctt cgcctgtccg
    10561 ccgctttcgg caagtccggc caatttcaag aggtcgcaca aggcgatgta ttcgttgtct
    10621 tcgagataga cgatggcttc catgatgtcc ccttgcagaa agagaccgtt attgtagcac
    10681 ctgccgccgc cgtacccaaa attaccgcaa aaccagcgat gtatccgcac cgcctgttcc
    10741 gtaaaagtaa aaatgccgtc tgaaaccccg tatgccgcaa tccgttcaaa gaaatcctgc
    10801 ccaacggcag actgcaaatc ctgttccccg acgaatccgc attgacgctg atgcacatcc
    10861 tcaaacacga actgcccgat acaccggcaa tcggcatcaa aacgaaatca aaaacctgtt
    10921 tgaacgtaaa attaatttaa ctgcttgcca tccgtccgaa taaggtatat agttccttat
    10981 aactagtttg atagtccttt atatctatca atactccttg ggaagcctcc accacacggt
    11041 aggaggcatt tttttgccgt cgtaaaagct caaaaacatt tgcaggtcat gccgtctgaa
    11101 tctgaaacgg catgacctac accgccatct aaagacaacc ctgctacaat acgcctttta
    11161 ttgttcacgc cgattttgcc atgaccgagc cgacctacat ccccctgcgc ctgcataccg
    11221 agttctcaat taccgacggt atggtgcgga ttaaaaaact gattgccaaa gcgcaggaat
    11281 acggtttgcc tgctttgggc atcagcgatt tgatgaacga attcggtttg gtgaaattct
    11341 ataaagcctg ccgcagtgcg gggattaagc ctgtcggggc ggcggacgtg tggataggca
    11401 atccgaatgc gcccgacaag ccgttccgcg ccatgttgat tatccgcaac gatgcgggct
    11461 atcagcgttt gagtgagctt ttgacagagg cctatgtcgg taaagaccgc aatgtccatc
    11521 atgcggaact caaccccgaa tggctggaaa acggcgacaa cagcggcttg atttgtttga
    11581 gcggcgcgca ttacggcgaa gtgggcatga atctgttgaa cggcaatgaa gacgcggcgc
    11641 gcgcggcggc gttgaaatat gcggcatggt ttcccgatgc gttttattta gagctgcaac
    11701 gcctgcccga acgccccgaa tgggaggctt gcgtttccgg cagcgtgaag ctggcggagg
    11761 aactgggttt gccggtggtg gcgacgcatc cgacgcagtt tatgaaccgc gacgatttca
    11821 acgcgcacga ggcgcgggtg tgtatcgcgg gcggctgggt attgacggac aaaaaacgtc
    11881 cgcgcgattt cacgccggac cagtttttca ttccgccgga aacgatgctg gagcgtttcg
    11941 ccgacttgcc cgaagccttg gaaaacacgg tggaaatcgc caaacgctgc aacctgcaca
    12001 tcacattggg caaaaacttc ctgccccttt tccccacgcc cgacggttta tcgcgcgatg
    12061 actatctcat caaactctca aacaagggct tgcaggaacg catggttcag ctttatcccg
    12121 acgaggcgga gcgtgcggca aaaatgccgg aatatcagga acgtttggat tttgagctga
    12181 acatcatcat ccagatgaaa ttccccggct atttccttat cgtacaagac tttatcaact
    12241 gggcgaaaac gcacggctgt ccggtcgggc cgggacgcgg ttcgggcgcg ggttcgctgg
    12301 tggcgtattc gctgaaaatt accgacctcg acccgctcaa atacgcgctg ctgttcgaac
    12361 gtttcttgaa ccctgaacgc gtttccatgc ccgacttcga cgtggacttc tgtcaggcaa
    12421 accgcggccg cgtgattgaa tatgtacgcg aaaaatacgg tgcggaagca gtcagccaga
    12481 ttgttacctt cggcacgatg tcgtccaaag cagtgattcg cgacgtgggg cgcgtactgg
    12541 aactgccgtt tatgctgtgc gacaaactgt ccaagctgat tccgttggaa gccaacaaac
    12601 ctttgggttt ggacgacgcg atgaaggcgg agccgcagat tcaggaatta atcgaagcgg
    12661 aagaagcgga cgaactgatt acgctggcga aaaagctgga agatttgacg cgcggtttgg
    12721 gtatgcacgc gggcggcgtg ttgattgcgc cgggcaagat ttccgattac agccccgtgt
    12781 atcaggcgga cgaatccgcc tcgcccgtat ccatgtacga caagggcgac gtggaagacg
    12841 tgggtttggt gaaattcgac tttttaggtc tgcgcaacct gaccatcatc gaaatggcgc
    12901 agaacaacat caaaaacacc accggcgaca tcatcgatgt cggcaaaatt ccgcttgacg
    12961 accaggttgc ctaccaaatc ttccgcgatg cgaacaccac cgccgtgttc cagttcgagt
    13021 cgacaggcat gaagaaaatg ctgaaaacag cgcatacgac caagtttgaa gaacttatcg
    13081 ccttcgtatc gctctaccga cccggcccga tggacaatat tcccgacttc gtcgcgcgta
    13141 tgaaaggtca ggaattccaa tacatccacc cgctactcga aggcatcctc gcaccaacct
    13201 acgggattat ggtgtatcag gaacaagtga tgcaggcggc gcagattatc ggcggctact
    13261 cgctcggcgg cgcggacctg ctgcgccgcg cgatgggtaa gaaaaagccc gaagaaatgg
    13321 tgaaacaccg cgaaatcttc gccgaaggcg cggcaaaaca aggcatttcg cgcgaaaaat
    13381 ccgacgaaat cttcaactat atggaaaaat tcgccggcta cggtttcaac aaatcccacg
    13441 ccgccgccta cgccctgatt tcctaccaga ccgcatggct caaggcgcac taccccgccg
    13501 aatttatggc ggcgaccatg tcgtccgaat tggacaacac cgaccagctc aagcatttct
    13561 acgacgactg ccgcgccaac ggcatcgagt tcctgccgcc cgacatcaac gaatccgact
    13621 accgctttac gccgtatccg gacatgaaaa tccgctacgc gctcggcgcg attaaaggca
    13681 cgggcgaagc cgccgtcgaa tccatcaccg ccgcgcggca aagcggcggc aagtttaccg
    13741 gcctgttgga cttctgcgag cgcgtcggca aagaacacat gaaccgccgc accctcgaag
    13801 ccctgatacg cggcggcgcg ttcgacagta tcgaacccaa ccgcgccatg ctcttggcga
    13861 acatcgacct cgctatggac aacgccgacc aaaaagccgc caacgccaat cagggcgggc
    13921 tgttcgacat gatggaagac gccatcgaac cggtgcggct catcgacctg ccgaggtgga
    13981 gcgaatcgga aaaactcgcc gaagaaaaaa ccgtcatcgg cttttacctg tccggccacc
    14041 cgttcggccc gtatgcccaa gaagtctgcc aaatcgcacc gaccaaatta gaccgtctga
    14101 agccgcaaga cagcgtgcgc ctcgccggat tcgttaccgc cgtgcgtacg atgatgggca
    14161 agcgcggcaa aatcgccttc gtcagccttg aagatttgag cgggcaggtt gaaatcatgg
    14221 tcggcagtca gacgctggaa aactgcgccg actgcctcaa agccgaccaa gtgctgatta
    14281 tcgaatccaa agtcagccgc gacgactacg gcggcggcga cggactgcgc atcatggcaa
    14341 accaagtcat gaccctgcaa acggcacgcg aacgctacgc ccgcagcctc agcctcgccc
    14401 tcgccccgca tcacgacatc ggcggactgg tacggctgct ctcctcccac caactgcccg
    14461 acacgccgcg catcccgctg caactgtcgt atgccaacga aaaagcgtcg ggcaggcttc
    14521 aagtgccgcc gaaatggacg gttacaccga gctccgcatt gttcggcgaa ctggaaacat
    14581 tgctcggcag ccggtcggtg cgcgtcaact ggtaacccaa aatataaatg ccgtctgaag
    14641 cccaaaatcg gtttcagacg gcatttttta accgaaataa acgatgcccc ttaaagcaga
    14701 agctttaagg ggcagagcgt tgcggcacat cttttcagac ggccttattg tagcaacggt
    14761 tctcatttcg cagtgcgaca atatgtttgg gattctagcc gttgtgagat gataagtcaa
    14821 taatctattt gtatataaat aagacaataa gatatattat cattatttgc aacgttgttt
    14881 acggagtaat aaatggctgc cttcaaacct aatccaatca actacatcct cggcctcgat
    14941 atcggcatcg catccgtcgg ctgggcgatg gtagaaattg acgaagaaga aaaccccatc
    15001 cgcctgattg atttgggcgt gcgcgtattt gagcgtgccg aagtaccgaa aacaggcgac
    15061 tcccttgcca tggcaaggcg tttggcgcgc agtgtccgcc gcctgacccg ccgtcgcgcc
    15121 catcgcctgc ttcgggcccg ccgcctattg aaacgcgaag gcgtattaca agccgctgat
    15181 tttgacgaaa acggcttgat caaatcctta ccgaatacac catggcaact tcgcgcagcc
    15241 gcattagacc gcaaactgac gcctttagag tggtcggcag tcttgttgca tttaatcaaa
    15301 caccgcggtt atttgtcgca aagaaaaaac gagggcgaaa ctgccgataa agagcttggc
    15361 gctttgctta aaggcgtggc caacaatgcc catgccttac agacaggcga tttccgcaca
    15421 ccggccgaat tggctttaaa taaatttgag aaagaaagcg gccatatccg caatcagcgc
    15481 ggcgattatt cgcatacgtt cagccgcaaa gatttacagg cggagctgat tttgctgttt
    15541 gaaaaacaaa aagaatttgg caatccgcat gtttcaggcg gccttaaaga aggtattgaa
    15601 accctactga tgacgcaacg ccctgccctg tccggcgatg ccgttcaaaa aatgttgggg
    15661 cattgcacct tcgaaccggc agagccgaaa gccgctaaaa acacctacac agccgaacgt
    15721 ttcatctggc tgaccaagct gaacaacctg cgtattttag agcaaggcag cgagcggcca
    15781 ttgaccgata ccgaacgcgc cacgcttatg gacgagccat acagaaaatc caaactgact
    15841 tacgcacaag cccgtaagct gctgggttta gaagataccg cctttttcaa aggcttgcgc
    15901 tatggtaaag acaatgccga agcctcaaca ttgatggaaa tgaaggccta ccatgccatc
    15961 agccgtgcac tggaaaaaga aggattgaaa gataaaaaat ccccattaaa cctttcttcc
    16021 gaattacaag atgaaatcgg cacggcattc tccctgttca aaaccgatga agacattaca
    16081 ggccgtctga aagaccgtgt tcagcccgaa atcttagaag cgctgttgaa acacatcagc
    16141 ttcgataagt tcgtccaaat ttccttgaaa gcattgcgcc gaattgtgcc tctaatggag
    16201 caaggcaaac gttacgatga agcctgcgcc gaaatctacg gagaccatta cggcaagaaa
    16261 aatacggaag aaaaaattta tctgccgccc atccctgccg acgagatccg caaccccgtc
    16321 gtcttgcgcg ccttatctca agcacgtaag gtcattaacg gcgtggtacg ccgttacggc
    16381 tccccagctc gtatccatat tgaaacggca agggaagtag gtaaatcgtt taaagaccgc
    16441 aaagaaatcg aaaaacgcca agaagaaaac cgcaaagacc gggaaaaagc cgccgccaaa
    16501 ttccgagagt atttccccaa ttttgtcggc gaacccaaat caaaagatat tctgaaactg
    16561 cgcctgtacg agcaacaaca cggcaaatgc ctgtattcgg gcaaagaaat caacttagtc
    16621 cgtctgaacg aaaaaggcta tgtcgaaatc gaccatgccc tgccgttttc gcgcacatgg
    16681 gacgacagtt tcaacaataa agtgctggta ttgggcagcg aaaaccaaaa caaaggcaat
    16741 caaacccctt acgaatactt caacggcaaa gacaacagcc gcgaatggca ggaatttaaa
    16801 gcgcgtgtcg aaaccagccg tttcccgcgc agtaaaaaac aacggattct gctgcaaaaa
    16861 ttcgatgaag acggctttaa agaatgcaat ctgaacgaca cgcgctacgt caaccgtttc
    16921 ctgtgccaat ttgttgccga ccatatattg ctgacaggta aagggaaaag acgtgtcttt
    16981 gcctcaaacg gacaaattac caatctgttg cgcggctttt ggggattgcg caaagtgcgt
    17041 gcggaaaacg accgccatca cgccttggac gctgtagtcg ttgcctgctc gaccgttgcc
    17101 atgcagcaga aaattacccg ttttgtacgc tataaagaga tgaacgcgtt tgacggtaaa
    17161 accatagaca aagaaacagg aaaagtgctg catcaaaaaa cacacttccc acaaccttgg
    17221 gaatttttcg cacaagaagt catgattcgc gtcttcggca aaccggacgg caaacccgaa
    17281 ttcgaagaag ccgatacccc agaaaaactg cgcacgttgc ttgccgaaaa attatcatct
    17341 cgccccgaag ccgtacacga atacgttacg ccactgtttg tttcacgcgc gcccaatcgg
    17401 aagatgagcg gtgcacataa agatactttg agatctgcta aacgatttgt taaacataat
    17461 gaaaaaatta gtgttaaacg agtatggtta accgaaatca agttggccga ccttgaaaat
    17521 atggttaatt ataaaaatgg tagagagatt gaattatatg aggctcttaa ggcgcgttta
    17581 gaggcatatg gaggtaatgc taaacaagca tttgacccta aggacaatcc gttttataaa
    17641 aagggaggac aactggttaa agctgtgagg gtcgaaaaaa cccaagagag cggagtctta
    17701 ttaaataaaa aaaatgctta taccattgca gataatggag acatggtacg tgttgatgtg
    17761 ttctgtaaag tagataagaa aggaaaaaat cagtatttta ttgttcccat ctatgcttgg
    17821 caggttgctg aaaacattct tcccgatatt gattgtaagg gataccggat tgatgatagc
    17881 tatacattct gttttagctt gcataagtat gatctgattg cttttcaaaa agatgaaaaa
    17941 tctaaagtag aattcgccta ctatatcaac tgtgatagct ctaatggacg attctattta
    18001 gcttggcatg ataaaggctc taaagaacag caattccgta ttagcaccca aaatcttgta
    18061 ttgatacaaa aataccaagt taacgaactg ggcaaagaaa tcagaccatg ccgtctgaaa
    18121 aaacgcccac ctgtccgtta aattaatctg tccctgcttc agacggcctg aagcagggat
    18181 tttttatatc aaaataaggg gaaaacatga cttggcgcag cctacttatt caaaacggcg
    18241 gcaaactatc cttgcaacgc cggcaactgc tgattcaaca aaacggcgag tcccataccg
    18301 taccattaga agacatcgcc gttatcatca tcgaaaatcg cgaaaccctg attaccgccc
    18361 cgctcctatc agccttagct gaacatggcg caaccctgct gacctgcgac gagcagttcc
    18421 tgccctgcgg acaatggctg ccttatgccc aatatcaccg ccagcttaaa atcctcaagc
    18481 tgcaactgaa cataagcgaa cccttaaaaa agcaattctg gcaacatatc gtccgccaaa
    18541 aaatcctgaa ccaagcattt atcgcagacg aaacaggcaa tgatcttgca gccaaacggc
    18601 tgcgcacttt ggcatctgaa gtccgttcgg gcgatacagg aaaccgtgaa gcccaagctg
    18661 ccgccctcta cttccaagcc ctctttggcg aaaaatttac ccgtaatgac aacaatgccg
    18721 tcaatgccgc attgaactac acctacgccg tgctacgggc cgcagttgca cgcaccctga
    18781 ccttatacgg ctggctgcct gcattaggct tgtttcatag aagcgaactc aatccattca
    18841 atctcgccga tgactttatc gaacccttac gcccattagc cgacctgacc gtgatacatt
    18901 tgtacgaaca aggccgtctg aaagccgaac tgacccccgg catcaaacaa caccttatca
    18961 aaacccttca ctatcaaatc agcatcgaac ggcaacattt cagcaccttg gctgccatcg
    19021 acaaaatggt ttcgtcattt caagccggtg taaccgataa aaacgccaaa caactgaaac
    19081 tgcctgaaat cctaccattg aaagaatacc gatatgagtg aggccaaatt tatgaggatt
    19141 atcgtcttct tcgacctacc ggttatcacg gcggcaaagc gcaaagccgc caatcaattc
    19201 cgccagtttt tattaaaaga cggataccaa atgctccagc tttccgtata cagccgtatc
    19261 gtcaaaggcc gcgattcgtt gcaaaaacac cacaatagac tatgtgcaaa ccttccgcaa
    19321 gaaggctcaa tccgctgttt ggagataaca gaaaagcaat atgccgccat gaaactgctg
    19381 ttgggcgagc tgaaaaccca agaaaaaaag gtcaattcag accaattatt gttattttaa
    19441 gcccattttt tcagactaaa taaaacggga aatccttata gaataaggat ttcccgttgg
    19501 ggtattgtag cactgcgaaa tgagaatggg agctacaact tcacacgtca tacaatggtc
    19561 ggtacagaga ttgtagcact gcgaaatgag aatgggagct acaacttaaa agaaaatgcc
    19621 aattaaacct tagcaattgt agcactgcga aatgagaatg ggagctacaa caaaatcgtc
    19681 ggcctgctcc agcacgacct gattgtagca ctgcgaaatg agaatgggag ctacaaccta
    19741 cccgctcggc gtatatgagg caatctaatt gtagcactgc gaaatgagaa tgggagctac
    19801 aacgcgcacg attgacggca gcagacgagc caaattgtag cactgcgaaa tgagaatggg
    19861 agctacaaca gcggtggtag aatcggattt ttagagtgaa ttgtagcact gcgaaatgag
    19921 aatgggagct acaaccgttt ttcaggtcga attatcgaac cttcaattgt agcactgcga
    19981 aatgagaatg ggagctacaa cgtcggcatt gttcagggtg ttcgcttcgc aattgtagca
    20041 ctgcgaaatg agaatgggag ctacaacaga acactatggc taaaacatca agtggcaatt
    20101 gtagcactgc gaaatgagaa tgggagctac aactcgcgca agcattgacg atatttgtga
    20161 ggcattgtag cactgcgaaa tgagaatggg agctacaaca aattttatga aaaccgtttc
    20221 caccgccgta ttgtagcact gcgaaatgag aatgggagct acaactatgc ttgggtttga
    20281 gtgggcgatt gatgaattgt agcactgcga aatgagaatg ggagctacaa ccttggcacg
    20341 agatggtcgc cgtattaaat tattgtagca ctgcgaaatg agaatgggag ctacaacttt
    20401 atggctattc acctgtcgag caaatcaatt gtagcactgc gaaatgagaa tgggagctac
    20461 aacaagaaga ttgggaaatg tatctcacgg aagattgtag cactgcgaaa tgagaatggg
    20521 agctacaacc ggtttgaaca gcagtatatg ggaagaaaca ttgtagcact gcgaaatgag
    20581 aatgggcgct acaaccagcc gttgcgataa gcgaacgtgc gttaaagtca ttgagacaca
    20641 gtgcaattat ggcaagaaag gcgacagata ttgtgtcaca gatttgaaat aagaaaaaac
    20701 cgcccactca cagagtaggc ggaaaacttg cgtttttttg attgtggtcg ggttagctac
    20761 tgcattgact taacagcaaa gcaaccgcta aaatgaactt gtggttcact tcaacggaca
    20821 gcagcaactt tttcccacgc ataaggaatt taagcatttt agcttctcct agtgaagtta
    20881 atcacacagg cgagagccga acaaaaatcc ccgttgcagc ggggattttt gctgttccct
    20941 gtttgatgat taaactaaaa tcttgcaaa
//
LOCUS       DAXISH010000037        20239 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.037, whole genome shotgun sequence.
ACCESSION   DAXISH010000037 DAXISH010000000
VERSION     DAXISH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 20239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20239
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.037"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(42..848)
                     /locus_tag="ACFOV4_001307"
     CDS             complement(42..848)
                     /locus_tag="ACFOV4_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HFC7619310.1"
                     /translation="MPTVFIFLTAVYAGLGAFAWHCQQQGLGRDYPWKTELPVLGAAL
                     TVHGAALLMPVIQDKIIIMGFGYSGSLIVWMMLFIYFAGSFFYPLRGVQLLLYPCAAL
                     MLLSGLVFPGKFSGYEITDLPFMLHIGTSLLAYGLFGIATLLSVLTLLLNRSLHRRNF
                     SKLAGFLPSLLSLEKLMFQAMWAGFILLTYSVVSGTFFAEAVFGKPMTFTHKTVFGIL
                     SWLIYGGLLLKHSMTAWRGKKAAVWTIIGFVSLMIAYMGSKFVLEIILKR"
     gene            1069..2439
                     /gene="ffh"
                     /locus_tag="ACFOV4_001308"
     CDS             1069..2439
                     /gene="ffh"
                     /locus_tag="ACFOV4_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFC7619311.1"
                     /translation="MLDNLTGRFSNVLKNIRGQAKLTEDNIKEALREVRLALLEADVA
                     LPVVKEFVNNVKEKALGQEVVGSLTPDQAFIGVVNKALTELMGRENKTLDLSVAPPAV
                     VLMAGLQGAGKTTTAGKLARLLKNDQKKKVLVVSADVYRPAAIEQLRLLAEQIGVDFF
                     PSDTNQKPVEIATAAVDYAKKHFYDVLMVDTAGRLAIDEEMMNEIKALHAAVNPVETL
                     FVIDAMLGQDAVNTAQAFNEALPLTGVVLTKMDGDSRGGAALSVRHVTGKPIKFIGVG
                     EKINGLEPFHPDRLASRILGMGDVLTLIEDVQKGIDEEAAAKMAKKLQKGKGFDLNDF
                     KEQIQQMRNMGGLENLMSKMPGELGQISKQIPEGTAEKAMGKVEAIINSMTPKERANP
                     ALLKASRKRRIAMGAGTTVQEVNKLLKQFEQMQQMMKMFSGNGLGKLMRMAKGMKGMK
                     GMFPGL"
     gene            complement(2770..3465)
                     /locus_tag="ACFOV4_001309"
     CDS             complement(2770..3465)
                     /locus_tag="ACFOV4_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HFC7619312.1"
                     /translation="MKLKTLALTSLTLLALAACSKQAETSVPADSVQSSSSAPAAPVE
                     LNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCAHLEPVLSEHIKTFKDDTYMRRE
                     HVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
                     DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQ
                     LVDKVREEQKKPQ"
     gene            complement(3639..4181)
                     /locus_tag="ACFOV4_001310"
     CDS             complement(3639..4181)
                     /locus_tag="ACFOV4_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFC7619313.1"
                     /translation="MLHLKDKINGTDQMDDLYRIFFYDCVPFEKKMHNPVSHRAIDFS
                     KTPEAIFRCNLHTELKKKRKLALRLGKLSDNTAWILKPQVMKNLLKNPSTQITENDVV
                     LDVKQKGVDMRIGLDISSITLKKQADKIILFSGDSDFVPAAKLARREGIDFILDPMWN
                     HVPPDLMEHIDGLKTKCPKP"
     gene            complement(4682..6793)
                     /locus_tag="ACFOV4_001311"
     CDS             complement(4682..6793)
                     /locus_tag="ACFOV4_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HFC7619314.1"
                     /translation="MKISFHLALLPTLIIASFPVAAADTQDNGEHYTATLPTVSVVGQ
                     SDTSVLKGYINYDEAAVTRNGQLIKETPQTIDTLNIQKNKNYGTNDLSSILEGNAGID
                     AAYDMRGESIFLRGFQADASDIYRDGVRESGQVRRSTANIERVEILKGPSSVLYGRTN
                     GGGVINMVSKYANFKQSRNIGAVYGSWANRSLNMDINEVLNKNVAIRLTGEVGRANSF
                     RSGIDSKNVMVSPSITVKLDNGLKWTGQYTYDNVERTPDRSPTKSVYDRFGLPYRMGF
                     AHRNDFVKDKLQVWRSDLEYAFNDKWRAQWQLAHRTAAQDFDHFYAGSENGNLIKRNY
                     AWQQTDNKTLSSNFTLNGDYTIGRFENHLTVGMDYSREHRNPTLGYNRDFSASINPYD
                     RASWPASGRLQPVFTQNRHKADAYGIFVQNIFSATPDLKFVLGGRYDKYTFNSESKLT
                     GSSRQYSGHSFSPNIGAVWNINPVHTLYASYNKGFAPYGGRGGYLSIDTLSSAVFNAD
                     PEYTRQYETGVKSSWLDDRLSTTLSAYQIERFNIRYRPDAQNNPYTWAVGGKHRSRGV
                     ELSAIGQIIPKKLYLRGSLGVIQAKVVEDKENPDRVGIHLNNTSNVTGNLFFRYTPTE
                     NLYGEIGVTGTGKRYGYNSRNKEVTTLPGFARVDAMLGWNHKNVNVTFAAANLFNQKY
                     WRSDSMPGNPRGYTARVNYRF"
     gene            complement(6979..7584)
                     /locus_tag="ACFOV4_001312"
     CDS             complement(6979..7584)
                     /locus_tag="ACFOV4_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFC7619315.1"
                     /translation="MTRQSLQQAAESRRSIYSLNKNLPVGKDEVVQIVEHAVLHTPSS
                     FNSQSARVVVLFGEEHDKVWQFVEDALRAVVPADSFEPTAQKLNLFKAGAATILFYED
                     QNVVKGLQEQFPAYAANFPVWADQANAMVQYAVWTTLAAVGVGANLQHYNPLPDAAIA
                     KAWNIPENWLLRAQMVIGGIEGAAGEKTFEPVAERLKVFGA"
     gene            complement(7633..8031)
                     /locus_tag="ACFOV4_001313"
     CDS             complement(7633..8031)
                     /locus_tag="ACFOV4_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HFC7619316.1"
                     /translation="MSDCCNRIQPVLLSVLRIVTAYLFLLHGTSKIFAFPIEMGSGSP
                     GGLLLLAGILEIVGGILLVLGLFARPAAFVLSGQMAVAYFMAHASGNALFPIANGGES
                     AVLFCFVFLYIAAAGGGAWSLDRLFFKRKA"
     gene            8139..9050
                     /locus_tag="ACFOV4_001314"
     CDS             8139..9050
                     /locus_tag="ACFOV4_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFC7619317.1"
                     /translation="MDTLFSLKVFRQVVQSGGFTRAADALGISTAMASKHVSHLENTV
                     QAKLLHRNSRNLSLTEAGEEYYRQCSYALDTLDDAAQKAAGGTEKPQGLLRVTMPLWF
                     AGSQICNWLAEYRERYPEVALELILDNRHVDLIAEGVDLALRVSQTLSPSLIARPLAE
                     IEFALLASPDFLRRNGVPETPEEVAGLPAVLPTYTNQQKLDLTRKSDGKKYRLELTPV
                     IRTDNTLMMREMIKAGACIGYQPLWAAEHDLRCGTLVRLLPGYAVPTDRLNAVYADRA
                     FLSAKVRSFIDFLNEKIASRKGCRNAV"
     gene            9040..10341
                     /locus_tag="ACFOV4_001315"
     CDS             9040..10341
                     /locus_tag="ACFOV4_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding domain-containing protein"
                     /protein_id="HFC7619318.1"
                     /translation="MPSETARPLYADTCAAHTLVWFRQNLRIRDNAALCAAVAEGLPV
                     IGIWIDDAETDNPRRAAFYRQSAAELAQGLAGRGIPLYTAASPAELVRLAVRLNIRAV
                     IADESHTFADKLADNALWHELDKHGIALTFVNDRAVFGKTDLIPDGGTAHTDFDRYRE
                     VWLDRFSKQPPAGPDLFAAYRQPFPENLSAPPPAALSDGIFLPQNSGETAAWRQWRRF
                     LEQADSYSVLKDFPSRKHTSLMGAYLSAGCISPRLLARESLERRLNAWADNIIRRDFF
                     LQLALQHTDDDPSDGNPEHTLRLTLWQQGRTGIPIIDAAMRCLHKTGSLHPALRRLSA
                     DFFCHVLNLPRREGEIWFARQLTDFDAAINQGNWWLAASRHTCPDIAAAAHKTDPDGT
                     FVRRHIPELAHLSADTVHTPWRFACSVDTHGYPAHPVAGIP"
     gene            complement(10409..10579)
                     /locus_tag="ACFOV4_001316"
     CDS             complement(10409..10579)
                     /locus_tag="ACFOV4_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619319.1"
                     /translation="MLLYRLLGGAEIECGRCPVPPMTDWQHFLPAMGTVSAWVAVIWA
                     YLMIESEKNGRY"
     gene            10736..12886
                     /gene="dinG"
                     /locus_tag="ACFOV4_001317"
     CDS             10736..12886
                     /gene="dinG"
                     /locus_tag="ACFOV4_001317"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HFC7619320.1"
                     /translation="MLTDLEKNAIRDHYQNIGKNLPGFRPRASQREMIAAVANAFSRT
                     LAREEGGEPPKREGESIAVIEGPTGVGKSLAYLLAGGIMAQTRGKRLIVSSATVALQE
                     QLVDRDLPFLVEKSGLELSFALAKGRGRYLCPYKLYQLTQSNAQQNLLGFEAPAVLWD
                     SKPKPEELKLLRDIADEFSARRFNGDRDAWPEKIDDAIWLKVTNDRHGCLKTACPNRP
                     ECPFYLARDVLETVDVVVANHDLLLADISMGGGVILPAPENSFYCIDEAHHLPKKALS
                     RFAAEHSWNMAVWTLEKLPQLTGKIAALTDKAELANLADEAASSLLDSLHEWQFHLAE
                     ELSLSLGPSENDRRTNSEPTWLWEDGKIPEGLETTVSNTAIAARSLLKHVVGLNDALS
                     AARREKEQDGALLDRLTGDFGIFIARIEQISAVWDLLSTVPIEGEEPLAKWITRRADD
                     KNDYIFNASPISSASHLANSLWRRAAGAVLTSATLQSLGNFNLMLRQTGLQWLPETTT
                     LALKSPFDFEKQGELYIPPIYASPKDPEAHTAAVIEWLPKLISPTEAIGTLVLFSSRK
                     QMQDVALRLPGDYLPLLLVQGELPKAVLLQKHHRAIEEGKASIIFGLDSFAEGLDLPG
                     TACVQVIIAKLPFAMPDNPIEKTQNRWIEQRGGNPFIEITVPEAGIKLIQAVGRLIRT
                     EQDYGRVTILDNRIKTQRYGQQLLAGLPPFKRIG"
     gene            12922..13536
                     /locus_tag="ACFOV4_001318"
     CDS             12922..13536
                     /locus_tag="ACFOV4_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HFC7619321.1"
                     /translation="MNFTRLLNQVLSTVQKKGNTFSDSPLNSFGGGALVAGVASMLLN
                     GKNRKTITKIGSTAALGYLAYRGYQMWQQNKGQATVTQSDFQPAGETEETYSRTVLRT
                     MIAAAASDGMIDEAERRTIEQESGTDPETAAWLAAEYRLPASIGDIATAVGNDEALAA
                     EAYLAARLVCADLSRKETVFLARLSQALKLDDNLVESLERQLGF"
     gene            complement(13827..15695)
                     /locus_tag="ACFOV4_001319"
     CDS             complement(13827..15695)
                     /locus_tag="ACFOV4_001319"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFC7619322.1"
                     /translation="MQAVRYRPEIDGLRAVAVLSVMIFHLNNRWLPGGFLGVDIFFVI
                     SGFLITGIILSEIQNGSFSFRDFYTRRIKRIYPAFIAAVSLASVIASQIFLYEDFNQM
                     RKTVELSAVFLSNIYLGFQQGYFDLSADENPVLHIWSLAVEEQYYLLYPLLLIFCCKK
                     TKSLRVLRNISIILFLILTATSFLPSGFYTDILNQPNTYYLSTLRFPELLAGSLLAVY
                     GQTQNGRRQTANGKRQLLSSLCFGALLACLFVIDKHNPFIPGMTLLLPCLLTALLIRS
                     MQYGTLPTRILSASPIVFVGKISYSLYLYHWIFIAFAHYITGDKQLGLPAVSAVAALT
                     AGFSLLSYYLIEQPLRKRKMTFKKAFFCLYLAPSLILVGYNLYARGILKQEHLRPLPG
                     APLAAENHFPETVLTLGDSHAGHLRGFLDYVGSREGWKAKILSLDSECLVWVDEKLAD
                     NPLCRKYRDEVEKAEAVFIAQFYDLRMGGQPVPRFEAQSFLIPGFQARFRETVKRIAA
                     VKPVYVFANNTSISRSPLREEKLKRFAANQYLRPIQAMGDIGKSNQAVFDLVKDIPNV
                     HWVDAQKYLPKNTVEIHGRYLYGDQDHLTYFGSYYMGREFHKHERLLKSSHGGALQ"
     gene            complement(15776..17146)
                     /gene="purB"
                     /locus_tag="ACFOV4_001320"
     CDS             complement(15776..17146)
                     /gene="purB"
                     /locus_tag="ACFOV4_001320"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0006188 - IMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFC7619323.1"
                     /translation="MINPIASLSPLDGRYAQSVEALRPIFSEYGLMKARVKVELNWLK
                     ALAAEPKIAEVPPFSAETLAEIDTVIENFSLEDAAAVKAIEATTNHDVKAIEYWLKKR
                     FAEVPEVAAVSEFIHFACTSEDINNLSHALMLQEAREAVLLPKLAEIIEKLTAMAHDL
                     AAVPMMSRTHGQPATPTTLGKETANVVYRLQRQFKNLQAQEFLGKINGAVGNYNAHMV
                     AYPDVDWETHCRNFVEISLGLTFNPYTIQIEPHDYMAEFFQTLSRINTILIDFNRDVW
                     GYISLGYFKQKVKAGEVGSSTMPHKVNPIDFENSEGNLGMANAVLGFLSEKLPISRWQ
                     RDLTDSTVLRNMGVGVGYAVLGFAAHLRGLNKLEPNPAALAADLDATWELLAEPIQTV
                     MRRYGVANPYEKLKDLTRGKGGITPEVLKGFIGLLEIPAEAKAKLLELTPALYVGKAE
                     ALAKRI"
     gene            complement(17218..17850)
                     /locus_tag="ACFOV4_001321"
     CDS             complement(17218..17850)
                     /locus_tag="ACFOV4_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFC7619324.1"
                     /translation="MENTNRVPEQARYDAERRQADEALAGVFPAVSIFGSARTPQNHA
                     DYAFACRLARRLSDSGIAVISGGGPGIMEAANKGAFAGKSVSVGLNIVLPHEQKPNPY
                     QDIALRFSRFAERKAVFFRYSQAYVVMPGGFGTLDELFEILTLVQTGKVPPRPIVLVG
                     KAFWSGLAEWINAQLLARGLISEGAASLFAISDDEDEIVAYLSEHGLQTA"
     gene            18159..20039
                     /locus_tag="ACFOV4_001322"
     CDS             18159..20039
                     /locus_tag="ACFOV4_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="HFC7619325.1"
                     /translation="MNIFYEESGQFKIAAIVQKNDATYQVDTPHGKRTKVKANNVFAE
                     FDGDMAAFLENAQAQAADIDTDLLWEVCGEEEFTAEAIAEEYYGHAPTKTELAATLIA
                     LYAAPMYFYKKAKGVFKAAPEETLKQALAAIERKKQQDAQIDAWAEALKRGEMPSEIA
                     ADLKTILHAPDKQSLTYKAFTKAADALKTSAYELAKKTGGITSIPQYLQDGFEIKYFP
                     KGTGFPDLALPEMPDLPKADVTAFSIDDESTTEVDDALSLTDLDNGTKRVGIHIAAPS
                     LAIKQGDKMEKNIMERLSTVYFPGGKITMLPENWIAAFSLDAGAYRPAVSIYFDVDSG
                     FNAGEPTCKIEAVNIAKNLRIQAIEPHFNAETGLDEAGEMMFVHHQDLIWFHQFAVAL
                     QKARGKYEPNRAPQYDYSIELDKEDNVSVVRRERGSPIDTLVSEMMILANSTWAQMLH
                     DNDLPGLFRVQPTGKVRMSTKSEPHIGMGVRHYGWFTSPLRRAADYINQKQLISLIDD
                     TAEPLYQNSDAELFAALRDFDAAYTAYADFQRQMEAYWSLVYLQQQGTSELTATILKE
                     DLVRIEGLPLVTRATGIPFDALPKSQALFKITELDAEKQFVSLNYIKAVAPAGTTAGN
                     AV"
BASE COUNT         5009 a         5571 c         5153 g         4506 t
ORIGIN      
        1 gtctgaaact cggggcttca gacggcatct gttggctctt cttatctttt cagaatgatt
       61 tccaatacga acttgctgcc catataggca atcatcaggc tgacaaatcc gatgatggtc
      121 cacacggcgg cttttttgcc gcgccatgcg gtcatgctgt gcttgagcag cagtccgccg
      181 taaatcagcc atgacaatat gccgaatacg gttttatggg taaaggtcat gggtttgccg
      241 aatacggctt cggcaaaaaa tgttccgctg acgacggaat aggtcagcag gatgaaacct
      301 gcccacatgg cctggaacat gagtttttcc aaactgagca gcgacggcag gaatcctgcg
      361 agcttggaga agttcctgcg gtgcaggctc cgattcagca gcagggtcaa aacggacaat
      421 aatgttgcga tgccgaacag cccgtatgca agcagcgaag ttccgatatg cagcataaag
      481 ggaaggtcgg taatttcata tcccgagaat tttccaggaa aaaccaaacc tgacagcagc
      541 atcagtgcgg cgcaaggata cagcagcaac tgcactccgc gcagcggata aaagaagctg
      601 ccggcaaaat aaataaacag catcatccaa acaatcaggc tgccggaata cccaaagccc
      661 ataatgatga ttttgtcttg aatgaccggc ataagcagtg ccgcgccatg gacggtcaat
      721 gccgcgccca aaaccggcaa ttccgtcttc cacgggtaat cccggccgag cccctgctgt
      781 tggcagtgcc atgcaaatgc acccaatcct gcgtaaaccg ccgtcaaaaa gatgaaaact
      841 gtcggcatgg tggactttct ctaatctata ctgttgcgct gtatgcggcc gcttatgaaa
      901 tattggaact tttaacgttg gaattgtaaa atccccgttt cgggcaagcc ttgacggatt
      961 tgccgatatg ctgtccggca cacaagccgc atcaaattat tttgatttta ttttaacaaa
     1021 gaatgcccct gatggggcaa gctattctta ttcagaccaa ggaccagtat gttagacaat
     1081 ttaaccggcc gcttcagcaa tgttctcaaa aacatccgcg ggcaggccaa actgaccgaa
     1141 gacaatatta aagaagcctt gcgcgaagtc cgcctcgccc tgcttgaggc ggatgtcgcc
     1201 ctgcctgtcg tcaaagagtt cgtcaacaac gtcaaagaaa aggccctcgg tcaggaagtg
     1261 gtgggcagcc tgacgccgga tcaggcattt atcggcgtgg tcaacaaagc cctgaccgag
     1321 ctgatgggca gggaaaacaa aacgctggat ttgtcggttg cgccgcccgc cgtcgtgttg
     1381 atggcaggtt tgcagggcgc gggcaagacg acgaccgccg gcaaactcgc ccgcctgctg
     1441 aaaaacgatc agaagaaaaa ggttttggtc gtatctgccg acgtttaccg ccctgccgcg
     1501 attgaacaac tgcgtctgtt ggccgaacag atcggcgtgg actttttccc atccgatacc
     1561 aaccaaaaac cggttgagat tgcaactgcc gccgtcgatt acgccaaaaa acatttttac
     1621 gatgtattga tggtcgatac cgccggccgt ttggcaatcg atgaggagat gatgaacgaa
     1681 atcaaagccc ttcacgcggc ggttaacccg gtggaaactt tgttcgtcat cgatgcgatg
     1741 ctgggtcagg atgcggtgaa cactgctcag gcatttaatg aagccctgcc gctgaccggt
     1801 gtcgtattga ccaagatgga cggcgattcg cgcggcggcg cagctttgtc cgtgcgccac
     1861 gtaaccggca agccgattaa atttatcggt gtcggcgaaa aaatcaacgg cctcgaacct
     1921 ttccaccccg accgtcttgc cagccgtatc ctcggcatgg gcgacgtatt gaccctgatt
     1981 gaagacgtcc aaaaaggtat tgatgaagaa gccgccgcca aaatggcgaa aaagctacaa
     2041 aaaggcaaag gcttcgacct caacgacttt aaagaacaaa tccagcaaat gcgcaatatg
     2101 ggcggtttgg aaaacctgat gtcgaaaatg ccgggcgaac tgggtcaaat atcgaaacaa
     2161 atccccgaag gaacggctga aaaagcgatg ggcaaagtgg aagccatcat caactcgatg
     2221 actccaaaag aacgcgccaa ccctgccctg ctcaaagcca gccgcaaacg ccgtattgca
     2281 atgggtgcgg gcacgaccgt acaggaagtg aacaaattgc tcaaacagtt tgaacaaatg
     2341 caacaaatga tgaagatgtt cagcggcaac ggcttgggca aactgatgcg tatggcgaaa
     2401 ggaatgaagg gaatgaaagg aatgttcccg ggtttgtaag ccgatttgac cgaaaacgcc
     2461 gtctaaaatt tcagacggcg tttttgtttt atattctgat ttatagtgga ttaacaaaaa
     2521 tcaggacaag gcggcgagcc gcagacagta cagatagtac ggaaccgatt cacttggtgc
     2581 ttcagcacct tagagaatcg ttctctttga gctaaggcga gccaacgccg tactggtttt
     2641 tgttaatccg ctatatattc tgatttaaaa ccataaggct ttaagcaatc atctcttcta
     2701 taaagcctaa atacaaaagg ccgtctgaaa tcctattttc agatggcctt tactcattca
     2761 atcctcaact tattgcggct ttttctgctc ttcgcgtact ttatccacca actggtcaat
     2821 cgtggtcata ccggactgcc agtctttaaa ttcaacttgg tatttgccgc cgacaatcac
     2881 agtcggtgtg ccgctgattt ggaatttatt ggtcaactct tccatttgag ccgcacgcgc
     2941 ttggctttca ggagcctcaa atgcagccaa tacttttttg ccgtcaaacg ctgtttgctc
     3001 ggacagccat tttttcaggg tatcggtatc ggccagattg attttttgat taaccatcgc
     3061 atcgaaaata tggctgttgg ctttatctga ttcaccggcc atttccactg cggccgccaa
     3121 acgtgccaaa ggtttcattt catcacccca cacgacatgc tcccggcgca tataggtatc
     3181 gtctttaaac gttttgatgt gctcgctcaa gaccggctca agatgggcgc aatgcgggca
     3241 gaagtagccg aaaaattcca atacttcgat tttaccggcc tgctgttgcg gaataggcgt
     3301 agacaataca gtgtagttca caccttcgtt caactcaaca ggggctgccg gagcagatga
     3361 gctgctttgg acgctgtctg ccggaacgct ggtttcagcc tgtttgctac aagcggccaa
     3421 tgccaacagg gtcaatgaag tcaaagctaa ggttttcagt ttcataggta tctcttgtgt
     3481 gtcagattaa tgtgcggatt ttatggcatt ttattgaagg cgtgttcgat ttgagtgaaa
     3541 aaatgtgttt agttttattt cagcctttat aaaggccgtc tgaaatatgg cttagataat
     3601 tagccttatt ttcagacggc cttctttgtt ctagtaattt acggtttcgg acattttgtc
     3661 ttcaatccgt cgatgtgttc cattaagtca ggtgggacat gattccacat aggatcaaga
     3721 ataaaatcga taccttcccg tctggctaat ttggctgctg ggacaaaatc ggaatcacca
     3781 gaaaacaaga tgattttatc ggcttgtttt tttaaggtaa tagatgaaat atccaagcct
     3841 atacgcatat ctacaccttt ttgtttaaca tcgagcacga catcgttttc cgtaatttga
     3901 gttgacgggt ttttcagaag atttttcatg acttggggtt ttaatatcca tgctgtattg
     3961 tccgacagct tgcctaaacg taacgctaat ttacgcttct tcttcaattc ggtatgcaga
     4021 ttgcaacgaa atatggcttc cggagtcttt gaaaaatcta tggcacgatg agatacggga
     4081 ttgtgcattt tcttttcaaa cggcacgcag tcgtaaaaga aaattctata taaatcatcc
     4141 atttgatctg tgccgttgat tttatctttc agatgcagca tcgaatatcg gaaagccaaa
     4201 tcgagacctt tgcaataaca taggttacta aaattttatg ctcaatctca ttttcaaaat
     4261 gcaaaacttt tctgattttt cctacttttt gctcaatatt aggaaagttt taggcaattg
     4321 aaaatttttt ggcgcatttt tatgcgtcaa atttcgttaa cagactattt ttgcaaaggt
     4381 ctcaaatcag caattctttt tgcatcgtgt ggattttgag acaggcctaa tgaccgtacc
     4441 cgcttaataa aaaatgcacc gtcaagcaaa atggcggttt tcatattgct tcccctatat
     4501 ttgtcaaaga tataaaaaag cccttgggat cggcataccc gctatgattt aatgggtaat
     4561 gcgtactgcc aagggcacta tttctttttg gattatactg atgtagataa agcctgtcaa
     4621 aaagttcgta tgctgaattt acggattatc aggattttca gacggccttt gcctgatttc
     4681 atcagaaacg gtaatttacc cgggcagtat agccgcgcgg attacccggc atagagtccg
     4741 aacgccaata tttttgattg aacagattgg ctgcggcaaa ggtaacgtta acatttttat
     4801 ggttccagcc aagcatggca tcaactcggg caaagcctgg aagcgtagtc acttctttat
     4861 ttcttgagtt gtaaccgtag cgtttgcctg taccggttac gccgatttcg ccgtagaggt
     4921 tttcggtcgg ggtataacgg aaaaacaggt tgccggtaac gttgctggta ttattcaaat
     4981 ggatgcccac tcggtcggga ttttctttgt cttcaacgac tttcgcctga atcacgccca
     5041 acgaaccgcg cagatagagt tttttgggga tgatttgccc gatggcggac aattccacgc
     5101 cacgcgaacg gtgtttgccg ccgactgccc aagtgtaggg attattttgt gcgtcggggc
     5161 ggtagcggat attgaagcgt tcgatttggt aggcggacaa tgtagtgctg aggcggtcgt
     5221 ccagccaact gcttttcacg ccggtttcgt attggcgggt gtactcgggg tcggcgttga
     5281 acacggcgga agacaacgta tcgatgctca aatagccgcc gcgtccgcca taaggcgcga
     5341 agcctttgtt atacgaggcg taaagtgtgt ggactgggtt gatgttccac actgcgccga
     5401 tgttggggct gaacgaatgg ccgctgtatt ggcggctgct gccggtgagt ttgctttcgg
     5461 aattaaaggt gtatttgtcg taacggccgc cgaggacgaa tttcaagtcg ggcgtggcgg
     5521 agaagatgtt ttgcacgaaa atgccgtagg cgtcggcttt gtgccggttt tgggtgaaga
     5581 cgggttgcag cctgcccgaa gccggccagc ttgcgcggtc gtaggggttt atggaggcgg
     5641 aaaagtcgcg gttgtaacct aaggtcgggt tgcggtgttc gcggctgtaa tccatgccta
     5701 cggtcaagtg gttttcaaaa cggccgatgg tgtagtcgcc gtttagcgtg aaattggacg
     5761 acagggtttt gttgtcagtc tgctgccagg cgtagttacg tttgattaag ttgccatttt
     5821 cgctgcctgc atagaaatga tcaaaatcct gcgccgccgt gcggtgggcg agctgccatt
     5881 gggcacgcca tttgtcgttg aaggcgtatt caaggtcgga acgccaaact tgcagcttgt
     5941 ctttgacaaa atcgttccgg tgggcgaacc ccatgcggta aggcagtccg aagcggtcgt
     6001 acacggactt ggtcggactg cggtcgggcg tgcgctccac attgtcgtag gtgtattgcc
     6061 ccgtccactt caagccgttg tcgagtttga cggtaatgct gggcgaaacc atgacatttt
     6121 tgctgtctat gccgctgcgg aacgaattgg cgcgcccgac ttcgccggtg agacggatgg
     6181 cgacgttttt gttcagcact tcgttaatgt ccatattcag gctgcggttt gcccacgaac
     6241 cgtaaaccgc accgatgttg cggctttgtt tgaagttggc gtatttgctg accatgttga
     6301 tgacgccgcc gccgttggtg cggccgtaaa gcacggaaga cgggcctttc aggatttcca
     6361 cgcgctcgat gttggcagta ctgcggcgca cttgtccgct ttcgcgcacg ccgtcgcggt
     6421 aaatatcgga tgcgtcggct tgaaaaccgc gcaggaaaat gctttcaccg cgcatatcgt
     6481 aggcagcgtc gatgccggca ttgccttcga ggatggaact caaatcgttc gtaccgtaat
     6541 ttttgttttt ctggatattg agcgtatcga tggtttgcgg cgtttctttg atgagctgtc
     6601 cgttgcgggt aacggcggct tcgtcgtagt tgatgtagcc tttgagtacg ctggtgtcgg
     6661 actgtccgac cacggaaacg gtaggtagcg tggcggtgta atgttcacca ttgtcctgcg
     6721 tatcggcggc agcgacaggg aaggaagcaa taatcagcgt gggtaataaa gctaaatgaa
     6781 atgatatttt catttttata ttcaatttaa caaaacaacc gaattatatt gcctcacgga
     6841 ggaaatgaga ataatttctt ttaactatat tgaacatgat atttgtaaac aaaggtctca
     6901 gaatgcggaa aactcgccgc ctgatactga aaaatgccgt ctgaacaggg ttcagacggc
     6961 atttttttga ccgcgaaatt atgcgccgaa cactttcaaa cgttctgcaa ctggttcaaa
     7021 ggtcttttca cctgccgccc cttcaatacc gccgataacc atttgcgcgc gcaacaacca
     7081 gttttcgggg atattccacg ctttggcaat cgccgcatcg ggcaagggat tgtaatgttg
     7141 caggtttgca cctacgccga ccgcggcaag tgtcgtccaa acggcatact gcaccatcgc
     7201 gtttgcctgg tccgcccaaa cgggaaagtt ggcggcataa gcagggaact gctcctgcaa
     7261 acctttgacg acattttgat cttcataaaa caaaatggtt gccgcacccg ccttaaacag
     7321 gttcaatttt tgcgcggtcg gttcaaaact gtcggcaggc acgacggcac gcagcgcgtc
     7381 ttcgacaaat tgccacacct tatcatgctc ttcgccaaac agcacgacca cgcgggcaga
     7441 ttgggaattg aacgaagaag gtgtgtgcaa aacggcgtgt tcgacgattt ggacaacttc
     7501 atctttgccg acgggcagat ttttatttaa cgaataaatg gaacggcggc tttcggcagc
     7561 ctgttgcaga gattgacggg tcatttcttt tcctcaaaaa cattcaacaa aatacacttt
     7621 aggcagtccg attcaggctt tacgcttgaa aaacagcctg tccagcgacc atgctccgcc
     7681 gcccgctgcc gcgatataga ggaatacgaa acagaacagc actgcggact cgccgccgtt
     7741 ggcaatcggg aacaaagcat ttccggaagc gtgcgccata aaataggcaa ccgccatctg
     7801 accggacaaa acaaacgcgg cagggcgcgc aaacaggccc aacaccagca aaatgccgcc
     7861 gacaatttct aaaataccgg caagcagcaa cagcccgccg ggcgaaccgc tgcccatttc
     7921 aatggggaag gcgaagattt tcgacgtacc gtgcaacaaa aacaggtagg cggttacgat
     7981 acgcaaaaca gaaagcaaaa ccggttggat acggttgcag caatcggaca taaaagctcc
     8041 tttgatattt gtcttcattt caggcggtag agtatagatg tttccccttt tcaaatatat
     8101 actgctttta ttgatacaac ttttccacac aagaaaatat ggacaccctg ttcagcctca
     8161 aggttttccg ccaagtcgtc caaagcggcg gcttcacccg cgccgccgac gcgctcggca
     8221 tctccaccgc aatggcaagc aaacacgtca gccacttgga aaacaccgtc caagccaaac
     8281 tcctgcaccg caacagccgc aacctcagcc tgaccgaagc cggggaagaa tactaccggc
     8341 aatgcagtta cgcactcgac acgctcgacg atgccgcgca aaaagccgcc ggggggacgg
     8401 aaaaaccgca ggggctgctg cgcgtaacga tgccgctgtg gtttgccggc agccagatat
     8461 gcaactggct ggcggaatac cgcgaacgtt atcccgaagt ggcattagaa ctgattttgg
     8521 acaaccgcca cgtcgatttg attgccgaag gcgtggattt agcgttgcgc gtttcccaaa
     8581 ccctgtcccc gtcgctgatt gcgcgcccgc tggcggaaat cgaatttgcc ctgctcgcct
     8641 cgcccgattt cctgaggcgc aacggcgtgc cggaaacgcc ggaagaagtg gcagggctgc
     8701 ccgccgtcct gccgacctac accaaccagc agaaactcga cctcacccgc aaatcggacg
     8761 gcaaaaaata ccggcttgaa ctgacccccg tcatccgtac cgacaacacg ctgatgatgc
     8821 gcgaaatgat taaggcgggc gcgtgcatcg gttatcagcc gctttgggcg gcggaacacg
     8881 atttgcgctg cggcacgctg gtgaggctgc tgcccggata cgccgtcccg accgaccggc
     8941 tgaatgccgt ttatgcagac agggcattct taagcgcgaa agtccgcagc ttcatcgatt
     9001 ttctgaacga aaaaatcgcc agcaggaaag gctgccgaaa tgccgtctga aaccgcccgc
     9061 cccctttatg cggacacgtg cgccgcacac acgctcgtct ggttccgcca aaacctccgc
     9121 atccgcgaca acgccgcctt atgcgccgcc gttgccgaag gtttgcccgt tatcggtatt
     9181 tggattgacg atgccgaaac agacaaccct cgccgcgccg cgttctaccg ccaatccgcc
     9241 gccgaactcg cccaagggct tgcagggcgc ggcatcccgc tctacacggc ggcgtcgcct
     9301 gccgagctcg tccggctcgc cgtccgcctc aatatccgcg ccgtcatcgc cgacgaatcc
     9361 catacttttg ccgacaaact cgccgacaac gccctttggc atgaattgga caaacacggc
     9421 atcgcgttaa ccttcgtcaa tgaccgcgcc gttttcggca aaaccgacct gatacccgac
     9481 ggcggcacgg cacacaccga tttcgaccgc taccgcgaag tatggctcga ccgcttttcc
     9541 aagcagcccc ccgccggtcc ggacctattc gcggcatacc gccaaccctt ccccgaaaac
     9601 ctttccgccc cgccgcctgc cgccctttca gacggcatct tcctgccgca aaacagcggc
     9661 gaaacggcgg cttggcggca gtggcggcgg tttctcgaac aggcggattc ctactccgtt
     9721 ttaaaggatt tcccctcgcg caaacacact tcgctgatgg gcgcgtattt gagtgccggc
     9781 tgcatctcgc cgcgcctgct cgcgcgggaa agcctcgaac gccgtctgaa cgcgtgggcg
     9841 gacaacatca tccgccgcga ttttttcctt caacttgcct tgcagcacac ggatgacgac
     9901 ccttcagacg gcaatcctga acacaccctg cgcctgacgc tttggcagca gggccggacc
     9961 ggcattccga ttatcgatgc cgcgatgcgc tgtttgcaca aaaccggcag cctccacccc
    10021 gccctgagac gcttgagcgc ggattttttc tgccacgttt taaacctccc ccgccgcgaa
    10081 ggcgagatat ggtttgcccg gcagctgacc gatttcgatg cggcaatcaa ccaaggcaac
    10141 tggtggcttg ccgcctcacg gcacacctgc cccgacattg ccgccgccgc acacaagacc
    10201 gaccccgacg gcacctttgt cagacggcac attcccgagc ttgcccacct gtccgccgac
    10261 accgtccaca cgccttggcg gtttgcctgt tcggtcgata cccacggcta tcccgcccat
    10321 cctgtcgccg gtattcccta agcggtacgg caacctaaaa caaatgccgt ctgaacttcc
    10381 gtttcagacg gcattgcgtc cgaatgactc aatatcttcc gtttttttca ctttcaatca
    10441 tcaggtatgc ccaaatcacc gccacccaag ccgacaccgt tcccatcgcc ggcaaaaaat
    10501 gctgccaatc cgtcatcggc ggcacagggc aacggccgca ttcgatttcc gcgccgccca
    10561 acaaccggta cagcaacata tccgcaatcc aaagcaacaa cgggtatttc aaacgctgca
    10621 accaaaaaac caaccacgtc cgcacgattc acctcacccc ccattccgac aacgatattg
    10681 taccgcttcc gtgcaatgtt aaaataagcc cacttctacc gccgtacaaa acgccatgct
    10741 caccgattta gaaaaaaacg ccatccgcga ccattaccaa aacatcggca aaaacctgcc
    10801 cggtttccgt ccgcgtgctt cgcagcggga aatgattgcg gcggttgcca acgctttttc
    10861 gcggacgttg gcgcgcgaag aaggcggcga gccgcccaag cgcgagggcg agagcatcgc
    10921 cgtaatcgaa gggccgaccg gcgtgggcaa atcgcttgcc tacctgctgg cgggcggcat
    10981 catggcgcag acgcgcggca agcggctgat tgtgagcagc gcaacggttg ccttgcagga
    11041 gcagttggta gaccgcgacc tgccgttttt ggtcgaaaaa agcggtttgg aactgagctt
    11101 cgcgcttgcc aaagggcgcg gccgctatct ctgcccctac aaactctatc aactgacgca
    11161 aagcaatgcc cagcaaaacc tgctcggctt tgaagccccc gccgtcttgt gggacagcaa
    11221 acccaagccc gaagaattga agctgctgcg cgacattgcc gacgaatttt ctgcccgacg
    11281 gttcaatggc gaccgcgacg cctggccgga aaaaatcgac gacgcgattt ggctcaaagt
    11341 gaccaacgac cgccacggct gcctgaaaac cgcctgtccc aaccgtccgg aatgtccgtt
    11401 ttacctggca cgcgatgtct tggaaaccgt cgatgtcgtc gttgccaacc acgatcttct
    11461 gcttgccgac atcagtatgg gcggcggcgt gattctgcct gcgcccgaaa acagtttcta
    11521 ttgcatagac gaagcgcacc acctgcccaa aaaagccctc agccgttttg ccgccgaaca
    11581 ttcatggaat atggccgttt ggacgctgga aaaactgccg cagctgaccg gcaagattgc
    11641 cgcgctgacc gataaagccg aacttgccaa ccttgccgac gaagccgcct catccttact
    11701 cgacagcctg cacgaatggc agttccattt ggcggaagag ctgtctttga gcttggggcc
    11761 gtctgaaaac gacaggcgga ccaacagcga accgacttgg ctgtgggaag acggtaaaat
    11821 ccccgaaggc ctcgaaacca ccgtttccaa tacggccatt gctgcgcgca gcctgctcaa
    11881 acacgttgtc gggctgaacg atgcgctttc cgccgcgcgc cgcgaaaaag aacaggacgg
    11941 cgcgctcctc gaccgcctga ccggcgattt cggcatcttc atcgcccgta tcgaacaaat
    12001 cagcgcggtt tgggatttgc tctctaccgt tcccattgag ggcgaagagc cgttggcgaa
    12061 atggataacc cgccgcgccg acgacaaaaa cgactacatt ttcaacgcca gccccatcag
    12121 cagcgcgtcc cacctcgcca acagcctgtg gcggcgtgcg gcaggcgcgg tgttgacctc
    12181 cgccaccctg caatccttgg gcaactttaa cctgatgctg cgccaaaccg ggctgcaatg
    12241 gctgcctgaa accaccaccc tcgccctcaa aagccccttt gactttgaaa aacagggcga
    12301 actctacatc ccccccatat acgccagccc caaagacccc gaagcacaca ccgccgccgt
    12361 catcgagtgg ctgcccaagc ttatttcgcc caccgaagcc atcggcacac tcgtcctgtt
    12421 ttcctcgcgc aaacaaatgc aggatgtcgc cctgcgcctg cccggagact acctgccgct
    12481 cctgctcgta caaggcgaat tgcccaaagc cgtcctcctg caaaaacacc accgggccat
    12541 agaagaaggc aaagccagca tcatcttcgg actcgacagc tttgccgaag gactcgacct
    12601 gcccggcacc gcctgcgtgc aagtcatcat cgccaaactc cccttcgcca tgcccgacaa
    12661 ccccatcgaa aaaacccaaa accgctggat agaacagcgc ggcggcaacc ccttcatcga
    12721 aatcaccgtc cccgaagccg gcatcaaact catccaggct gtcggccgcc tcatccgcac
    12781 cgaacaagac tacggccgcg taaccatcct cgacaaccgc atcaaaacac agcggtacgg
    12841 ccaacaatta ttagccggcc tgccaccgtt taaaaggata gggtaaacct accgcccttc
    12901 ccgcaacaga aaggaaaagt catgaacttc acccgactgc tcaaccaagt cttaagcacg
    12961 gttcaaaaaa aaggcaacac attctccgac agcccgctca attcattcgg cggaggcgcg
    13021 ctggttgccg gtgtcgcctc catgctactg aacggtaaaa accgcaaaac catcaccaaa
    13081 atcggttcga ccgccgcttt gggctacctc gcctaccggg gctatcagat gtggcagcaa
    13141 aacaaagggc aggcaaccgt aacacaaagc gatttccaac ctgccggaga aactgaagaa
    13201 acatacagcc gcaccgtatt gcgcaccatg atagccgccg ccgcttcaga cggcatgata
    13261 gacgaagccg aacgccggac tatcgaacag gaaagcggca cagaccccga aactgccgca
    13321 tggctcgccg ccgaataccg cctgcccgca agcatcgggg acatcgccac cgccgtcggc
    13381 aacgatgagg cgttggcggc ggaggcctat ctggcggcaa ggttggtctg tgccgatttg
    13441 tcgcggaaag aaaccgtctt cctcgcccgc ctgtcgcagg ctttgaaact ggatgacaat
    13501 ctggtggaga gtttggaaag gcaattgggg ttttgatgac acagctgggg agggaaaatc
    13561 atcaaaaaac ggttattccg accccggcct caaaacggca aaatatagtg gattaacaaa
    13621 aaccagtacg gcgttgcctc gccttagctc aaagagaacg attctctaag gtgctgaagc
    13681 accaagtgaa tcggttccgt actatttgta ctgtctgcgg cttcgtcgcc ttgtcctgat
    13741 ttttgttaat ccactataaa agccgccgcc ccgaacggca aacagcggca taggctgcca
    13801 aaggcaatat ccgacaagaa ggcaggctac tgcaatgcgc cgccgtggga agatttaagc
    13861 aggcgttcgt gtttgtggaa ttcccgcccc atataataag aaccgaaata ggtcaggtgg
    13921 tcttggtcgc cgtaaagata gcgtccgtgt atttcgaccg tgtttttggg caggtatttt
    13981 tgtgcgtcca cccaatgcac attggggata tctttaacca aatcaaaaac cgcctgattg
    14041 ctcttgccga tgtcgcccat agcctgaatg gggcggagat attggtttgc ggcaaatctt
    14101 ttcaattttt cctccctcag gggcgaacgg ctgattgatg tgttgtttgc aaaaacatag
    14161 acgggtttga cggcggctat ccttttgacg gtttccctga atcgggcttg gaacccgggt
    14221 attaggaagg attgcgcttc aaatctcggc acgggctggc cgcccatcct caaatcatag
    14281 aattgggcaa tgaaaacggc ttcggctttt tcaacttcat cccggtattt tcgacataac
    14341 gggttgtctg ccagcttctc atctacccaa accaaacact ccgaatcgag ggacaggatt
    14401 ttggctttcc acccttcccg gctgccgaca taatccagaa acccccgcag gtgtccggcg
    14461 tgcgagtcgc cgagggtcag gacggtttcc ggaaaatgat tttccgcagc aaggggcgcg
    14521 ccgggcaacg ggcggaggtg ttcctgtttc aatatccccc ttgcgtacag gttgtaaccg
    14581 acaagtatca gggacggggc gagatagagg cagaaaaatg cctttttgaa ggtcatcttc
    14641 cgttttctaa gcggctgttc aatcaaataa taactcaaca gggaaaatcc ggccgtcaac
    14701 gcggcaaccg ccgatacggc aggcagtccg agctgtttgt cgcctgtaat gtaatgggcg
    14761 aaagcaataa aaatccaatg gtacaggtat agggaataag agattttgcc gacaaatacg
    14821 atggggcttg ccgacaggat gcgggtcgga agtgtcccgt attgcatact ccggataagc
    14881 agtgccgtca gcaggcaggg aaggagcagg gtcattcccg ggataaacgg attgtgtttg
    14941 tcaatcacga acaggcaggc aagcaatgcg ccgaagcaga gtgatgaaag caactgccgt
    15001 tttccatttg ctgtttgccg tctgccgttt tgcgtttgcc cgtaaaccgc cagcagcgaa
    15061 cctgccaaca gctcgggaaa cctcagtgtc gaaaggtaat aagtattggg ttggttgaga
    15121 atatcggtat aaaacccgct tggcaaaaac gatgtggcag tcaaaatcag aaataggatg
    15181 atgctgatgt tacgcagcac ccgtagcgat tttgtttttt tgcagcaaaa tatcagcaaa
    15241 agaggataca ggaggtaata ctgttcctct actgccaaag accagatatg cagtacgggg
    15301 ttctcgtcgg cactcaaatc gaaatacccc tgctgaaacc ccagataaat attggacaag
    15361 aaaaccgcag aaagctccac ggttttccgc atttggttga aatcttcgta aaggaagatt
    15421 tgagaggcaa tcaccgaagc cagcgacacg gccgcaataa aagcaggata aatccgctta
    15481 atcctgcggg tataaaaatc ccggaaagaa aaagaaccgt tctgtatttc agaaagaatg
    15541 atgccggtaa tgaggaatcc tgagatgaca aagaaaatgt ccacccccag gaatcctccg
    15601 ggcagccagc ggttattcag gtggaaaatc atgacggata gcacggcgac ggcccgcaat
    15661 ccgtcaattt ccggtctgta tcggacagct tgcataaata tcgcccccgt atgtcccgtt
    15721 atcttaaaaa tgccgtctga acgcgcgttc agacggcatc ggtttcagta aacgctcaaa
    15781 tccgtttcgc caacgcttca gccttgccca catacagcgc gggggtcagc tcaagcaatt
    15841 tggctttggc ttcggcgggg atttccagca atccgataaa gcctttcagc acttcgggcg
    15901 tgatgccgcc tttgccgcgc gtcaggtctt tcagtttttc gtaaggattg gcgacaccgt
    15961 aacggcgcat cacggtttga atcggctcgg cgagcagttc ccaagtggca tccaaatcag
    16021 cggcaagcgc ggcagggttg ggttcgagct tgttcagacc gcgcaggtgg gcggcgaaac
    16081 ccaacacggc atagcccacg cccacgccca tattgcgcaa tacggtgctg tcggtcaggt
    16141 cgcgctgcca gcgggaaatc ggcagttttt cggacaaaaa gcccaatacg gcattggcca
    16201 taccgaggtt gccctcggag ttttcaaagt cgatggggtt gactttgtgc ggcatggtcg
    16261 atgagccgac ttcgcccgct ttgacttttt gtttgaagta acccaatgaa atataacccc
    16321 aaacgtcgcg gttaaagtcg atcagaatcg tgttgatgcg gctgagggtt tggaagaatt
    16381 ccgccatata gtcgtgcggc tcgatttgga tggtgtaggg gttgaaggtc agaccgaggc
    16441 tgatttcgac gaagttgcgg cagtgggttt cccaatctac atcaggatag gcgaccatat
    16501 gggcgttgta gttgccgacc gcgccgttga ttttgccgag gaactcttgc gcttgcaggt
    16561 ttttaaactg gcgttgcagg cggtacacga cattggcggt ttctttgccc aaagtggtcg
    16621 gcgtggcggg ctggccgtgg gtgcggctca tcatcgggac ggcggcaagg tcgtgcgcca
    16681 tagcggtcag tttttcgatg atttcggcca gcttcggcag caaaacagcc tcacgcgctt
    16741 cttgcagcat taaagcgtgg gacaggttgt tgatgtcttc gctggtgcag gcgaagtgga
    16801 tgaactcact cacggcggcg acttccggca cttcggcaaa acgttttttc agccaatatt
    16861 caatggcttt gacatcatga ttggtcgtgg cttcgatggc tttgacggcg gccgcgtctt
    16921 ccaatgaaaa gttttcaatc accgtgtcga tttcggcaag cgtttcggca ctgaagggcg
    16981 gcacttcggc aatcttcggc tcggcggcga gggctttgag ccagtttaat tcgactttga
    17041 cgcgcgcttt catcaggccg tattcggaaa aaatcgggcg caatgcttca acggattggg
    17101 cataacggcc gtctaaaggg gaaagcgagg cgatggggtt gatcatttcg gcatcctgtt
    17161 cgggaaagac atcaaaaatt gttaaattgt ttgcaattat acatcactct caggacgcta
    17221 tgccgtctga agcccgtgtt ccgacagata cgcaacgatt tcgtcttcat cgtccgatat
    17281 ggcgaacaaa gaggctgccc cttcggaaat cagaccgcgc gccaaaagct gcgcgtttat
    17341 ccactccgcc aagcccgacc aaaacgcctt tccgaccaaa acaatcggac gcggcggcac
    17401 tttgcccgtc tgcaccaagg tcaggatttc aaacaattcg tccagcgtcc cgaagccgcc
    17461 cggcatcacg acatatgctt gggaatagcg gaaaaacacc gccttgcgtt cggcaaaacg
    17521 ggaaaaccgc aaggcgatgt cctgatacgg attcggtttc tgctcgtgcg gcaaaacgat
    17581 gttcagcccc accgaaaccg acttccctgc aaacgcgccc ttgtttgccg cctccataat
    17641 ccccggcccg ccgcccgaaa tgacggcaat gcccgaatcc gacagccgcc gcgccagacg
    17701 gcaggcgaac gcataatccg catgattctg cggcgtgcgc gcgctgccga agatactgac
    17761 tgccggaaac acgcccgcca atgcttcgtc tgcctgcctg cgttcggcat cataacgtgc
    17821 ctgctccggc acacggtttg tattctccat tccatcctcc gttcaaaaac agcgattgta
    17881 caccgtcaaa aacgtatagt ggattaacaa aaatcaggac aaggcgacga agccgcagac
    17941 agtacaaata gtacggaacc gattcacttg gtgcttcagc accttagaga atcgttctct
    18001 ttgagctaag gcgaggtaac gctgtactgg tttttgttaa tccactataa cgcaagcacc
    18061 gcaaagacgc gccaaccctc tcccaacctt ttttcagacg gcattttcgg taatctgcta
    18121 aaatcgcccg cttgagtttc cacagaaaaa tccgaaaaat gaatattttt tacgaagagt
    18181 ccggccaatt caaaatcgcc gccatcgtcc aaaaaaacga cgccacctac caagtcgata
    18241 ccccacacgg caaacgcacc aaagtgaagg cgaacaacgt ctttgccgag tttgacggcg
    18301 atatggcggc gtttttggaa aacgcgcagg cacaggcggc ggacatcgac accgatttat
    18361 tgtgggaagt atgcggcgaa gaggaattta ccgccgaagc catcgccgaa gaatattacg
    18421 gccatgcgcc gaccaaaacc gagctggcgg caactttgat tgcgctttac gccgcgccga
    18481 tgtatttcta caaaaaagcc aaaggcgtgt tcaaagccgc gcccgaagaa actttaaaac
    18541 aagcacttgc cgccatcgaa cgcaaaaaac agcaagacgc gcaaatcgac gcttgggcgg
    18601 aagccttgaa acgcggcgag atgccgtctg aaatcgcggc ggatttgaaa accatcctgc
    18661 acgcgcccga caagcagtcg ctgacctaca aagcctttac caaagccgcc gacgcgctga
    18721 aaacctctgc ctacgaattg gcgaaaaaaa cgggcggcat tacgtccatt ccccaatacc
    18781 tgcaagacgg atttgaaatc aaatacttcc ccaaaggaac aggcttcccc gaccttgccc
    18841 ttcctgaaat gcccgacctg cccaaggctg acgttaccgc cttttccatt gacgacgaat
    18901 cgaccaccga agtggacgac gctttaagcc tgaccgactt ggacaacggc acgaagcgcg
    18961 tcggcatcca catcgccgcg ccgtcgcttg ccattaaaca aggcgacaaa atggaaaaaa
    19021 acatcatgga acgcttgagc acggtttatt tccccggcgg caaaatcacg atgctgcccg
    19081 aaaactggat agccgcgttc agccttgatg caggcgcgta ccgtcctgcc gtcagcattt
    19141 attttgatgt ggacagcggg ttcaacgccg gcgaaccgac ctgcaaaatc gaagcggtca
    19201 acatcgccaa aaacctgcgc atccaagcca tcgagccgca tttcaacgcc gaaaccggct
    19261 tggacgaagc aggcgaaatg atgttcgtcc accatcaaga cctgatttgg ttccaccaat
    19321 ttgccgtcgc cctgcaaaaa gcacgcggca aatacgagcc caaccgtgcg ccgcaatacg
    19381 attacagcat cgaattggat aaagaagaca acgtatccgt cgtccgccgc gaacgcggtt
    19441 cgcccatcga tacgctggtc agcgagatga tgattcttgc caacagcact tgggcgcaaa
    19501 tgctccatga caacgacctg cccggcctct tccgcgtcca acccaccgga aaagtacgca
    19561 tgagcaccaa atccgagccg catatcggca tgggcgtgcg gcattacggc tggtttacct
    19621 cgccgctgcg ccgcgccgcc gactacatca accaaaagca gctgatcagc ctgatagacg
    19681 acactgccga gccgctgtat caaaacagcg atgccgagct tttcgccgca ctgcgcgact
    19741 ttgatgccgc ctataccgcc tacgccgact tccaacgcca aatggaagcc tactggagcc
    19801 tggtttacct gcaacagcaa ggcacgagcg agctgacggc gacgattctg aaagaagacc
    19861 tcgtccgcat cgaaggtctg ccgctagtaa cacgcgcgac cggtattccg tttgacgcgc
    19921 tgcccaaatc gcaggcattg ttcaaaatca ccgaattaga tgccgagaag cagtttgtct
    19981 cgctcaacta catcaaggca gtcgcacccg cgggtacaac ggcaggcaat gccgtctgaa
    20041 gcccgatacg gcaaactccg gcaaaaacag aaacctgaat ctcatcattc ccacagtcgg
    20101 gaatccggtt ttttgggttt ccgttgtttt tccgtttcaa tgaacttcca agccgccgtt
    20161 cccgataaat acccgcaatc taaaatcccg tcattcccac gcagatggga atctaggttt
    20221 atccgcacag aaactgata
//
LOCUS       DAXISH010000038        19979 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.038, whole genome shotgun sequence.
ACCESSION   DAXISH010000038 DAXISH010000000
VERSION     DAXISH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 19979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19979
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.038"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..297)
                     /locus_tag="ACFOV4_001323"
     CDS             complement(<1..297)
                     /locus_tag="ACFOV4_001323"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619326.1"
                     /translation="MQHKPLPYQWGKFWNNTIKPEKQAMFFHSICQCIRFQYVSRIKM
                     YSGLTKIKTRRRSRPPPEKRKKCRPKTFRTAFSRKPSFPQGHKTKTENRNQKPKI"
     gene            289..1212
                     /gene="lpxC"
                     /locus_tag="ACFOV4_001324"
     CDS             289..1212
                     /gene="lpxC"
                     /locus_tag="ACFOV4_001324"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008759 - UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine deacetylase activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HFC7619327.1"
                     /translation="MLQRTLAKSISVTGVGLHSGERVALTLHPAPENSGISFRRTDLD
                     GEMGEQIKLTPYLINDTRLSSTIVTDKGVRVGTIEHIMSALSAYGIDNALIELNAPEI
                     PIMDGSSLPFIYLLQDAGVVDQKAQKRFLKILKPVEIKEAGKWVRFTPYDGFKVTLTI
                     EFDHPVFNRSSPTFEIDFAGKSYIDEIARARTFGFMHEVEMMRAHNLGLGGNLNNAIV
                     IDDTDVLNPEGLRYPDEFVRHKILDAIGDLYIVGHPIVGAFEGYKSGHAINNALLRAV
                     LADETAYDRVEFADSDDLPDAFHELNIRTCG"
     gene            2303..3751
                     /gene="gnd"
                     /locus_tag="ACFOV4_001325"
     CDS             2303..3751
                     /gene="gnd"
                     /locus_tag="ACFOV4_001325"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019269816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating NADP(+)-dependent
                     phosphogluconate dehydrogenase"
                     /protein_id="HFC7619328.1"
                     /translation="MKGDIGVIGLAVMGQNLILNMNDCGFKVVAYNRTIGKVDEFLNG
                     AAKGTDIVGAYSLQDLVDKLAKPRKIMMMVRAGSVVDDFIEQLLPLLEEGDIIIDGGN
                     ANYPDTTRRTHYLAEKGILFVGAGVSGGEEGARHGPSIMPGGDERAWEAVKPIFQAIA
                     AKTPQGEPCCDWVGRDGAGHFVKMVHNGIEYGDMQLICEAYQFMKDGLGLSYDEMHRV
                     FAEWNKTELDSYLIEITAAILGYKDEGGEPLVEKILDTAGQKGTGKWTGINALDLGIP
                     LTLISEAVFARCVSSFKEQRVQTGKLFARTVTPVEGGKQEWVEALRQALLASKIISYA
                     QGFMLIREAGESYGWDLDYGNTALLWREGCIIRSAFLSNIRDAYENNPDLVFLGADPY
                     FKNILENCLPTWRKVVAKAVECGIPMPCMASAITFLDGYTTERLPANLLQAQRDYFGA
                     HTYERTDKPRGEFFHTNWTGKGGDTASTTYDI"
     gene            3814..5085
                     /gene="waaA"
                     /locus_tag="ACFOV4_001326"
     CDS             3814..5085
                     /gene="waaA"
                     /locus_tag="ACFOV4_001326"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HFC7619329.1"
                     /translation="MFQWLYDVLWLLAPIWIRRYLDKRSGSAPAYRAHRDERFGKPYP
                     NPVTGAVWIHAVSVGETRAAQPLIRELRQRFPDAPLLMTQMTPTGRETAQVLFPDAQC
                     RYLPYDKKTWVRQFLREHRPMFGILMETEIWPNLMTECRKSGVPLFLANARLSEKSLN
                     GYLKVRRLIRPAAASLTGCLAQTEADAARLAKLGAASVQVCGNTKYDLMPSEQMKTLA
                     GQFEKRIGDRQVAVCGSTRVYRGEDEAEKLLAAWQQYRGDALLVVVPRHPEHFQTVFE
                     TAKRFGFKVQRRSDGLPVEPDTQVWIGDSMGELYAYYLCADVAFVGGSLVDSGCQNII
                     EPLSCGVPTIFGFSTYNFSEACWHALASGAAVQVESADAWREAVEKTLSSKGGGMQMQ
                     VRVDGFIAQHRGAGARIAEAVREAVCGHRGR"
     gene            5126..5575
                     /locus_tag="ACFOV4_001327"
     CDS             5126..5575
                     /locus_tag="ACFOV4_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopD family copper resistance protein"
                     /protein_id="HFC7619330.1"
                     /translation="MSIYAVAHIVHLYCAIAFVGGVFFEVLVLSVLHTGLVSCEARRE
                     VENAMSYRAVRVMPFVVGLLFASGIVMAANRYLSILGEPFATSFGTMLTLKILLAFSV
                     LAHFAIAVVKMARSTLTVGWSKYIHTVVFTHMLLIVFLAKAMFYISW"
     gene            5608..6582
                     /locus_tag="ACFOV4_001328"
     CDS             5608..6582
                     /locus_tag="ACFOV4_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HFC7619331.1"
                     /translation="MTEYPGIGSPLFYGVFFAAVLVMIALDMFSLKKNGSHKVGIKEA
                     LAWSGLWVAVSCLFAGWLYFELAGNPGYGAAVAKEKVLEFFTGYILEKSLAVDNIFVF
                     LMIFGYFKVAPQFQHRVLLYGVLGALVLRTVMIFVGAALVRQFEWILYLFGAFLLYTG
                     IHMMKPEGDEEGDLANSRLLNAVKKVVPVGTEFHGEKFFTVENGKKIATPLFLVLVMI
                     ELSDVVFAVDSIPAVFAVTTDPFIVLTSNIFAILGLRAMYFLLSDVEERFIFLKYGLA
                     FVLSFIGVKMLVMHWVHIPISVSLSVVFGALGASILTSLIYTKKQPDK"
     gene            6651..6726
                     /locus_tag="ACFOV4_001329"
     tRNA            6651..6726
                     /locus_tag="ACFOV4_001329"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6684..6686,aa:Lys,seq:ttt)
     gene            6946..8199
                     /gene="murA"
                     /locus_tag="ACFOV4_001330"
     CDS             6946..8199
                     /gene="murA"
                     /locus_tag="ACFOV4_001330"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFC7619332.1"
                     /translation="MDKLKISANGPLNGEITVSGAKNAALPLMCAGLLTSGTLRLKNV
                     PMLADVKTTQKLLQGMGARVLTDNISEFEINGGTVNNTCAPYELVRTMRASILVLGPT
                     LARFGEAQVSLPGGCAIGSRPVDQHLKGLEAMGAEIVIEHGYVKAKGKLKGTRVAMDV
                     VTVGGTENLLMAATLAEGTTVLENCAIEPEVVDLAECLVKMGAKISGIGTSTMIVEGA
                     DELHGCEHSVVPDRIEAGTFLCAVAITGGRVVLRNAAPKTMEVVLDKLVEAGAVIEAG
                     DDWIAIDMRQRPKAVDIRTVVHPGFPTDMQAQFMALNAVAEGSCRVVETIFENRFMHV
                     PELNRMGANITTEGNTAFVQGVEQLSGAVVKATDLRASASLVIAGLAARGETVVEQIY
                     HLDRGYENIEKKLGSVGAKIERVSG"
     gene            8280..9458
                     /locus_tag="ACFOV4_001331"
     CDS             8280..9458
                     /locus_tag="ACFOV4_001331"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFC7619333.1"
                     /translation="MAFLKLTEQNVQGKTVLIRADMNVPFKDGKISDDTRIRASLASI
                     QYCMDNGASVIVMIHLGRPTEGEFHPEDDVAPVAAHLGGLLGKDVKVLNDWRENKPAL
                     NAGDVVMLQNVRINKGEKKNDLELGKAYASLCDVFVNDAFGTAHRAQASTEAVAQAAP
                     VACAGVLMAGELDALGKALKQPARPMVAIVAGSKVSTKLTILESLADKVDQLIVGGGI
                     ANTFLLAEGKAIGKSLAEHDLVEESKKIMAKMAAKGGSVPLPTDVVVAKAFAADAEAV
                     VKDIADVAEDDMILDIGPKSAAELAELLKAAGTVVWNGPVGVFEFDQFAGGTKALAEA
                     IAQSKAFSIAGGGDTLAAIAKFGVTDQIGYISTGGGAFLEFLEGKELPAVAALEKRGA
                     "
     gene            complement(9525..9773)
                     /locus_tag="ACFOV4_001332"
     CDS             complement(9525..9773)
                     /locus_tag="ACFOV4_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990229 - iron-sulfur cluster assembly
                     complex [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family protein"
                     /protein_id="HFC7619334.1"
                     /translation="MLTPEQVKAMIEDVAKCEHIKVEGDGHHFFAVIVSSEFEGKARL
                     ARHRLIKDGLKAQLESNELHALSISVAATPAEWAAKAQ"
     gene            complement(9863..10780)
                     /gene="ftsX"
                     /locus_tag="ACFOV4_001333"
     CDS             complement(9863..10780)
                     /gene="ftsX"
                     /locus_tag="ACFOV4_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFC7619335.1"
                     /translation="MSIIHYLSLHVESARTALKQLLCQPFGTLLTLIMLAVAMTLPLF
                     MYLGIQSGQSVLGKLNESPQITIYMETAAAQSDSDTVRSLLARDKRLDNIRFIGKEDG
                     LEELQSNLDQNLISMLDGNPLPDVFIVTPDPATTPAQMQAIYRDITKLPMVESASMDT
                     EWVQTLYQINEFIRKILWFLSLTLGMAFVLVAHNTIRLQILSRKEEIEITKLLGAPAS
                     FIRRPFLYQAMWQSILSAAVSLGLCGWLLSAVRPLVDAIFKPYGLNIGWRFFYPEEIV
                     LVFGFVIALGVFGAWLATTQHLLGFKAKK"
     gene            complement(10777..11427)
                     /gene="ftsE"
                     /locus_tag="ACFOV4_001334"
     CDS             complement(10777..11427)
                     /gene="ftsE"
                     /locus_tag="ACFOV4_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFC7619336.1"
                     /translation="MIRFEQVSKTYPGGFEALKNVSFQINKGEMIFIAGHSGSGKSTV
                     LKLISGITKPSRGKILFNGQDLGTLSDNQIGFMRQHIGIVFQDHKILYDRNVLQNVIL
                     PLRIIGYPPRKAEERARIAIEKVGLKGRELDDPVTLSGGEQQRLCIARAVVHQPGLLI
                     ADEPSANLDRAYALDIMELFKTFHEAGTTVIVAAHDETLMADYGHRILRLSKGRLA"
     gene            complement(11424..11615)
                     /locus_tag="ACFOV4_001335"
     CDS             complement(11424..11615)
                     /locus_tag="ACFOV4_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619337.1"
                     /translation="MPSESASDGIFPARPSVSAKLIHYLKTGGIFIIGTVLPIVQTAY
                     PCGRNRPKRYAAHSLQDLL"
     gene            complement(11623..12105)
                     /locus_tag="ACFOV4_001336"
     CDS             complement(11623..12105)
                     /locus_tag="ACFOV4_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFC7619338.1"
                     /translation="MKYLNLAAITLGATFAAHTASADELAGWKDGAAQSLQSLKAPVR
                     IVNLWATWCGPCRKEMPAMSKWYKAQKKGSVDMVGIALDTSDNIGNFLKQTPVSYPIW
                     RYTGANSRNFMKTYGNTVGVLPFTVVEAPKCGYRQTITGEVNEKSLTEAVKLAHSKCR
                     "
     gene            12229..12582
                     /gene="arsC"
                     /locus_tag="ACFOV4_001337"
     CDS             12229..12582
                     /gene="arsC"
                     /locus_tag="ACFOV4_001337"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271974.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HFC7619339.1"
                     /translation="MSEIKIFHNPRCSKSRAALSLLEERGIAAEVVKYLDTPPDLSEL
                     KDIFNKLGLESARGMMRVKDDLYKELGLDNPDLDNNALLRAIADHPALLERPIVLANG
                     KAAVGRPLENIEAVL"
     gene            12579..13235
                     /locus_tag="ACFOV4_001338"
     CDS             12579..13235
                     /locus_tag="ACFOV4_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFC7619340.1"
                     /translation="MNKRLFCSRNGLRYYLLGGFCLSVFPLLLVFTSSVWAVYRTGGQ
                     VLPPYVRADAALVLGAAAWDKRPSPVFRERINHAIALYQSRRVGKIVFTGGRTKKGYM
                     TEAEVGRRYALKQGVPARNILFENTSRNTYENLNNIRPVLRANGIASVVIVSDPYHLA
                     RAAEMAEDLGVRVYMSATPTTRFDAGNKKKIFMLQEGYALSLYRLEKWGSRFLGWLSD
                     "
     gene            13351..14745
                     /gene="gltX"
                     /locus_tag="ACFOV4_001339"
     CDS             13351..14745
                     /gene="gltX"
                     /locus_tag="ACFOV4_001339"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFC7619341.1"
                     /translation="MTVKTRFAPSPTGYLHIGGVRTALFSWAFARHHKGEFLLRIEDT
                     DLARSTAESVNIILDGMKWVGLDYDNAGNVVYQTRRFDRYKEVIAELLEKGDAYYCYC
                     SKEELEAMREKAEKEGTATYDRRWRPEAGKTLPEIPAGVQPVVRFKTPLDGVTKWTDL
                     VKGEISIPNEALDDLIIARADGTPTYNFCVVVDDYDMGVTHVIRGDDHVNNTPKQINI
                     LKAIGATLPEYGHLPMILNEQGKKISKRSGDTVAITDFGAMGILPEAMLNYLARLGWA
                     HGDDEFFTMEQFIEWFDLKDVSPSPSRMDLKKLYWINGEHIKITPNGKLAELVKPRLA
                     LRDIHETEKPALEDVLALVKDRAQDLNTLADECLYFYVKQTPTEADVQKHWDDEAAAR
                     MLRFAERLEGLEDWNAEAIHDLFKPFCDEEGIKMGKLGMPLRLAVCGTAKTPSVDAVL
                     ALIGKEEVLKRIRA"
     gene            14766..15161
                     /locus_tag="ACFOV4_001340"
     CDS             14766..15161
                     /locus_tag="ACFOV4_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619342.1"
                     /translation="MPSDVGMRLQTAFKRKLNMKKILYFLMFVFSTSVWAGDAEDNLL
                     SIQSGYRALLQKQNNLDGKIIGMQSDLEDARRRLQTAQADIARLEAEIPAAMAQKARQ
                     AEELRQIGVRLDYAWNAVYGAGGTKASGN"
     gene            15165..15656
                     /locus_tag="ACFOV4_001341"
     CDS             15165..15656
                     /locus_tag="ACFOV4_001341"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC7619343.1"
                     /translation="MNSLFVDNTVFITRLKAGHIGRLVQALFEEWHGFEPWSSVDKIH
                     AYYGRCLKDDELPLAFAAVDDFGTLLGSAAVKRHDMESFPQYEYWLGDVFVLPEYRGK
                     GIGRRLVAHCIGAARSLGIKFLYLYTPDVQIFYESFGWAVVGRHFHNGEWVTVMRLDM
                     DKV"
     gene            complement(15779..18373)
                     /gene="mutS"
                     /locus_tag="ACFOV4_001342"
     CDS             complement(15779..18373)
                     /gene="mutS"
                     /locus_tag="ACFOV4_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFC7619344.1"
                     /translation="MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAA
                     KLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEVGAGKGPV
                     ERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDK
                     LDDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRG
                     FGLDGKEHAVAIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEIT
                     QTLSGKKSPTLMSTLDLCTTHMGSRLLALWLHHPLRNRAHIRARQEAVTALDSQYEPL
                     QCRLKNIADIERIAARIAVGNARPRDLAALRDSLFALSEIDLSTNGSSLLETLKAVFP
                     ENLSTAEQLRQAILPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERE
                     RTGLSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAFEDKVL
                     TAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEF
                     ADYPVIHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIV
                     LLAHTGCFVPADAATIGPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSL
                     VLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFATHYFELTYLPEAHAAALNMHL
                     SALEQGQDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKSAQKHLNGLENQAAANRP
                     QLDIFSTMPSEKGDEPNVGNFVDKAEEKHFEGILAAALEKLDPDSLTPREALSELYRL
                     KDLCKSVS"
     gene            18817..19821
                     /gene="gap"
                     /locus_tag="ACFOV4_001343"
     CDS             18817..19821
                     /gene="gap"
                     /locus_tag="ACFOV4_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003766473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFC7619345.1"
                     /translation="MSIKVAINGFGRIGRLALRQIEKAHGIEVVAVNDLTPAEMLLHL
                     FKYDSTQGRFQGTAELKDDAIVVNGKEIKVFANPNPEELPWGELGVDVVLECTGFFTN
                     KTKAEAHIRAGARKVVISAPSGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMA
                     AVLQKEFGVVEGLMTTIHAYTSDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPVATGSLTELVSVLERPVTKEEINAAMKAAASESYGYNEDQ
                     IVSSDVVGIEYGSLFDATQTRVMTVGGKQLVKTVAWYDNEMSYTCQLVRTLEYFAGKI
                     "
BASE COUNT         4603 a         4892 c         5660 g         4824 t
ORIGIN      
        1 gattttaggt ttctgatttc ggttttctgt tttggtttta tgtccttgtg ggaatgacgg
       61 tttacgcgaa aatgccgtcc gaaaggtttt cggacggcat tttttgcgtt tttcaggagg
      121 ggggcggctt cgtcgccttg tcttgatttt tgttaatcca ctatacattt ttatgcggct
      181 tacgtattga aaacggatac attggcaaat actatggaaa aacatagctt gtttttccgg
      241 ttttatcgta ttattccaaa acttacccca ttgataagga agcggtttat gctgcaaaga
      301 actttggcga aatccatcag cgttaccgga gtcgggctgc attcgggcga acgcgtcgcg
      361 ctgaccctgc accccgcgcc tgaaaacagc gggatttcct tccgccgtac cgatttggac
      421 ggcgagatgg gcgaacaaat caagctgacc ccttatttga tcaacgatac ccgcctttcc
      481 tccaccatcg ttaccgacaa aggcgtgcgc gtcggcacga tcgaacacat tatgtccgcg
      541 ctgtccgcct acggtatcga caacgcgctg attgagctga acgcgcccga aatcccgatt
      601 atggacggct ccagcctgcc gtttatttac cttttgcaag atgcgggcgt ggtcgatcaa
      661 aaggcgcaaa agcgtttttt gaaaatcctc aagcctgtcg aaatcaaaga agcgggcaaa
      721 tgggtgcgct ttacgccgta tgacggcttt aaggtaacgc tgaccatcga attcgaccat
      781 ccggttttca accgcagctc gcccactttt gaaattgatt tcgccggcaa atcctacatc
      841 gacgaaatcg cgcgcgcgcg cactttcggc tttatgcacg aagtggaaat gatgcgcgcc
      901 cacaatctgg gtttgggcgg caatttgaac aacgctatcg tgattgacga cacggatgtc
      961 ctgaatcctg aaggcttgcg ctatcccgat gagtttgtgc gccacaaaat ccttgatgcc
     1021 atcggtgatt tgtatatcgt cggacatccg attgtcggcg cgtttgaagg ctacaaatcg
     1081 ggacacgcca tcaacaacgc actcttgcgc gcggttttgg cagacgaaac ggcttacgac
     1141 cgggtggaat ttgccgacag cgatgatttg cccgacgcat ttcacgagct gaacatcaga
     1201 acttgtggat aacgctttct attttttccg gtaaattcct aaaacttaaa atttcatcat
     1261 tcctacaagg acaaaaaacc aaaacagaaa cctaaaattc gtcattcccg cgaacctaca
     1321 tcccgtcatt cccacgaaag tgggaatcca gaacgcaaaa tctaaagaaa ccgctttccc
     1381 gataagtttc cgtaccgaca gacctagatt cccgcctgcg cgggaatgac ggcggagcgg
     1441 tttctgtttt ttccgataaa tgccgcaatc tcaaatcccg tcattcccac gaaagtggga
     1501 atctagaatc tcggactttc agataatctt tgaatattgc tgttattcta aggtctagat
     1561 tcccgcctgc gcgggaatga cggcggagcg gtttctgttg ctcccgataa attcctaaaa
     1621 cttaaaattt catcattccc actttcgtgg gaatgacggg atgtaagttc gtgggaatga
     1681 cgcggtacag gtttccgtta cgtatcccca tccgaaagtt tacttataca caagcaatcc
     1741 aaagttatct gactgaaata ttgtgagatt tacccgcaaa tctcattttc tccaccactt
     1801 atacacaaac tcggatgcac actctgccaa tatgcagaga aaaagacatt cgtgccgtta
     1861 acttactatt cccacacgtt ccaaacacat ttccctctca aacctccaca gtattcccgt
     1921 tcttaaaggc gccagcagcc attcggtaaa gaaaagtagg atgccatctg cacaacaagc
     1981 aaactgtcca caaaaactat tcttcatgaa aaacaatcca caggtatgca caaaagggaa
     2041 tccgccttac cgacaccctt ttaaaacggc aatctcgatg atttttaaaa taaaaaaaag
     2101 ttacccacag aaaatgtctc ctatcaatat aatcatcgtt ttattattta aattttatat
     2161 tttatttata agccttcagg gaaacgcacg gtaaagcgta aaggcatctt ttcaaaaaat
     2221 taaaaagtta aggattgtta aacaagtgta aatcaggtag agttgcggtc gataaattaa
     2281 atctataacg gagcttcctg caatgaaagg cgatattggt gtaatcggtt tggcggttat
     2341 ggggcaaaac ctgattttga atatgaacga ttgcggattt aaggttgtcg cctacaaccg
     2401 aacaatcggt aaggtggacg aatttttaaa cggcgcggct aagggaacgg atattgtcgg
     2461 cgcgtattcc ctgcaagact tggtcgataa gctggcaaaa ccgagaaaaa tcatgatgat
     2521 ggttcgcgca ggttcggtgg ttgacgactt tatcgaacaa ctgcttccgt tgttggaaga
     2581 aggcgacatc attatcgacg gcggcaatgc caattacccc gacacgacac ggcggacaca
     2641 ttaccttgcc gaaaaaggga ttttgtttgt cggcgcgggc gtatccggcg gcgaagaagg
     2701 cgcgcggcac ggcccgtcta tcatgccggg cggagatgag cgcgcttggg aagccgtcaa
     2761 accgattttt caggcgattg ccgccaaaac gccgcagggc gaaccgtgtt gcgactgggt
     2821 cggcagggac ggcgcggggc attttgtcaa aatggtgcat aacggcatcg aatacggcga
     2881 tatgcagttg atttgcgaag cgtaccagtt catgaaagac ggcttggggc tgtcttacga
     2941 cgaaatgcac cgcgtgtttg ccgagtggaa caaaaccgag ctggattctt atctgattga
     3001 aatcacagcg gcaattttgg gctataagga cgaaggcggc gaaccgctgg tcgagaaaat
     3061 cctcgatacg gcagggcaaa aaggcacggg caaatggacg ggcatcaatg ctttggattt
     3121 gggtattccg ttgacgctga tttccgaagc ggtattcgcc cgctgcgttt cgtcgttcaa
     3181 agaacagcgc gtgcagaccg gcaagctatt cgcccgaacc gttacgcccg tcgaaggcgg
     3241 caaacaagaa tgggttgagg cgttgagaca ggccctgctt gcatctaaaa tcatttccta
     3301 cgcacaaggc ttcatgctga tccgcgaagc gggcgaaagc tacggctggg atttggacta
     3361 cggcaacact gcgctgctgt ggcgcgaggg gtgcatcatc cgcagcgcat tcttaagcaa
     3421 tatccgcgac gcgtatgaaa acaatcccga tttggtgttc ttgggtgcgg atccgtattt
     3481 caaaaatatt ttggaaaact gcctgccgac gtggcgcaag gtggttgcca aggcggtcga
     3541 atgcggcatc cctatgcctt gcatggcttc ggcgattacg ttcttggacg gctacacgac
     3601 cgaacgtctg cctgccaacc tcttgcaggc acagcgcgac tacttcggcg cgcacactta
     3661 cgaacgcacc gacaaaccgc gcggcgagtt tttccatacc aactggacgg gcaagggcgg
     3721 agataccgct tcgacaacct acgatatttg attccgttgc cgaaatgccg tccgaaccgt
     3781 tcggacggca tttgttttgc aggaaataga aagatgttcc aatggcttta tgatgtattg
     3841 tggctgcttg cgccgatatg gatacggcgt tatttggaca aacgctccgg aagtgccccg
     3901 gcatatcggg cgcatcggga cgagcgtttc ggcaagccgt atccgaatcc cgttaccggc
     3961 gcggtttgga tacacgccgt ttcggtcgga gaaacgcgtg ccgcccagcc cttgatacgc
     4021 gagttgcggc agcgttttcc cgatgcgccg ctgctgatga cgcagatgac cccgacggga
     4081 cgggaaaccg cgcaagttct gtttcctgat gcacaatgcc gttatcttcc gtatgacaaa
     4141 aaaacgtggg tacggcagtt tttgcgcgaa caccgcccga tgttcggcat tttgatggaa
     4201 accgaaatct ggcccaacct gatgacggag tgccggaaat cgggcgttcc gctgtttttg
     4261 gcgaatgcgc ggctgtcgga aaaatcgcta aacggttatc tgaaagtccg ccgcctgatc
     4321 cgtcctgccg ccgcttcgct gacgggttgt ctggcgcaga cggaggcgga tgcggcgcgg
     4381 ttggcgaaat tgggcgcggc atccgtgcag gtgtgcggca ataccaaata cgacctgatg
     4441 ccgtcggaac agatgaaaac gctggcgggg cagtttgaaa aacgcatcgg agaccggcag
     4501 gttgccgtgt gcggcagcac gcgcgtttat cggggtgaag acgaggcgga aaaactgctg
     4561 gcggcgtggc aacaatatcg cggcgatgcg ctgctggtcg tcgtgccgcg ccatcccgag
     4621 cattttcaga cggtatttga aacggcaaaa cgcttcgggt ttaaggttca gcggcgcagc
     4681 gacggtttgc cggtcgaacc tgatacgcag gtgtggatag gcgacagtat gggcgagctg
     4741 tatgcgtatt acttgtgcgc cgatgtcgct tttgtcggcg gcagtctggt cgattcgggc
     4801 tgtcagaaca ttatcgaacc gctttcctgc ggcgttccga cgatattcgg cttttcaacc
     4861 tacaattttt ccgaagcctg ctggcacgcc ttggcatcgg gggcggcggt tcaagtcgaa
     4921 tcggcggatg cgtggcgtga agccgttgaa aaaaccttat cgtccaaggg gggcggaatg
     4981 cagatgcagg tgcgcgtgga cggctttatc gcacaacatc gcggagcggg cgcgagaatc
     5041 gccgaggcgg tgcgggaagc ggtatgcgga catcgggggc gatagtgata caatccgtat
     5101 ccgagttttc cgtttggagc atcgtatgag tatttatgcc gtcgcgcaca tcgttcatct
     5161 gtattgcgct attgcctttg tcggcggcgt gttttttgaa gtgctggttt tgtccgtcct
     5221 gcatacggga ctggtgtcgt gcgaggcgcg gcgcgaagtg gaaaatgcaa tgtcttaccg
     5281 cgccgtcagg gtgatgccgt ttgtggtcgg actgctgttc gccagcggca tcgtgatggc
     5341 ggcaaaccgc tatctttcta tattgggcga accgtttgcc acttccttcg gtacgatgct
     5401 gacgctgaaa atcctgttgg cgttcagcgt gttggcgcac ttcgccatcg ccgtcgtcaa
     5461 aatggcgcgt tccacactga ccgtcggctg gtcgaaatac atacacaccg tcgtctttac
     5521 ccatatgctg ctgattgtct ttttggcaaa agcgatgttt tatatcagct ggtaacacaa
     5581 ttacatttca aatcaggaga ttgaaccatg acagaatatc ccggcatcgg gtcgccgttg
     5641 ttttacggcg ttttttttgc ggcagtgctg gtcatgattg ccttggatat gttttcgctg
     5701 aagaaaaacg gcagccataa agtcggcatc aaagaagcct tggcatggag cggcttgtgg
     5761 gttgccgtat cctgcctgtt cgcgggctgg ctgtatttcg aactcgccgg caatcccggc
     5821 tacggcgcgg cagtcgcaaa agaaaaagta ttggaattct ttaccggcta cattttggaa
     5881 aaatcgttgg cagtcgataa tattttcgtg ttcctgatga tattcggcta cttcaaagtc
     5941 gcaccgcagt ttcagcaccg cgtgctgctg tacggcgtat tgggcgcatt ggtattgcgc
     6001 accgtcatga ttttcgtcgg cgcggcactg gttcggcagt tcgagtggat tctgtatctg
     6061 ttcggcgcgt tcctgctcta taccggcata cacatgatga agcccgaagg cgatgaggaa
     6121 ggggatttgg caaacagcag gctgctgaat gccgtcaaga aagtcgttcc ggtcggcacg
     6181 gaatttcacg gcgagaaatt ttttaccgtc gaaaacggca aaaaaatcgc cacgccgctg
     6241 tttttggtgc tggtcatgat tgaattgagc gatgtcgtgt ttgccgtgga cagcatcccc
     6301 gccgtctttg ccgttaccac cgatccgttt atcgtgctga cctccaatat tttcgccatt
     6361 ttgggtttgc gggcgatgta tttcctgctg tcggatgtgg aggaacgctt tatcttcctg
     6421 aaatacggct tggcattcgt gttgagtttt atcggtgtga aaatgctggt aatgcattgg
     6481 gtgcatatcc cgatttccgt ttcgctgtcg gtcgtgttcg gcgcgttggg tgcatcgata
     6541 ctgacctcgt taatttatac gaaaaaacag cctgataaat aaaatgccgt ctgaacgccg
     6601 acaaaatggt tgacagcatc aggcttgatg tatagaattt cgagcttatc gggtcgttag
     6661 ctcagtcggt agagcagcgg acttttaatc cgttggtcga gcgttcgaat cgctcacgac
     6721 ccaccagata aaacaaaaaa agctgagttt tcaaaactcg gctttttttg tcttccgaca
     6781 atccttgttc ggaaagcgcg gcatttcgtc aaattctttg gtgcggcttc cgtatttttc
     6841 ccgaaaatcc cttataattc cgcctctgca accttcatcg ggtgatgctt tatgcgttgt
     6901 cccgagtatt gaaatattac aagtacccac caggaaagaa caaacgtgga caaactgaaa
     6961 atctccgcaa acggcccgct caacggggaa ataacggtct cgggcgcgaa aaacgcggca
     7021 ttgccgctga tgtgcgcggg tttgctgaca tcgggtacgt tgcgcctgaa aaatgtgcct
     7081 atgctggcag atgtgaaaac cacacaaaag ctgcttcagg ggatgggcgc gcgcgtcctg
     7141 accgacaata tcagtgaatt tgaaatcaac ggtggtacgg taaacaacac ctgcgcccct
     7201 tacgaattgg ttcggacgat gcgggcctcg attttggtgc tggggccgac gctggcgcgt
     7261 ttcggcgagg cgcaagtcag cctgccgggc ggctgcgcca tcggttcgcg ccccgtcgat
     7321 cagcatttga aaggcttgga agcgatgggt gctgagattg ttatcgaaca cggttacgtc
     7381 aaagccaaag gcaaactcaa aggtacgcgc gtggcgatgg atgtcgttac cgtcggcggc
     7441 acggaaaacc tgctgatggc ggcgacgctg gcggaaggta cgacggtttt ggaaaactgc
     7501 gccattgagc ctgaagtggt cgatttggcg gaatgcctgg tcaaaatggg cgcgaaaatc
     7561 agcggcatcg gtacgtccac aatgattgtg gaaggtgcgg acgagctgca cggctgcgaa
     7621 cacagcgtcg tccccgaccg gattgaggcg gggacgttcc tgtgcgcggt ggcgataacc
     7681 ggcggcaggg tggttttgcg gaatgccgcg ccgaaaacga tggaagtggt gttggacaaa
     7741 ctggttgagg caggtgcggt gattgaagcg ggcgacgatt ggatcgccat cgatatgcgg
     7801 cagcgtccga aggcggtgga catccgcacg gtcgtccacc ccggcttccc cacggatatg
     7861 caggcgcagt ttatggcatt gaatgccgtg gcggagggaa gctgccgcgt ggtggaaacg
     7921 atttttgaaa accgctttat gcacgtcccc gagttgaatc gaatgggggc gaacattaca
     7981 accgagggca atacggcatt tgtgcagggt gtggaacagc tttccggcgc ggtcgttaag
     8041 gcgacggatt tgcgtgcgtc cgccagcctc gttatcgccg gtttggcggc gcgaggcgaa
     8101 accgtggtcg aacagattta ccacttggat cgcggttatg aaaatattga aaaaaaactc
     8161 ggcagcgtcg gcgcgaaaat cgagcgcgta tccggctgat cgggttgcga tgccgtctga
     8221 agccttcaga cggcatcaat tgtttctgta tcgcaaacac tgattgaaaa ggactgatta
     8281 tggcattttt aaaactgacc gaacaaaacg tgcagggcaa aaccgtcctc atccgcgccg
     8341 atatgaacgt gccgttcaaa gacggcaaaa tcagcgacga cacccgtatc cgcgcctcgc
     8401 tcgcgtccat ccaatactgc atggacaacg gcgcatccgt tatcgtgatg atccacttgg
     8461 gtcgcccgac tgaaggcgag ttccaccccg aagacgacgt tgcgcccgtt gccgcgcatt
     8521 tgggcggtct gttgggcaaa gacgtgaaag tattgaacga ctggcgcgaa aacaaaccgg
     8581 ctttgaacgc gggcgatgtc gtgatgctgc aaaacgtgcg tatcaacaaa ggcgagaaga
     8641 aaaacgattt ggaactgggt aaagcctacg cttctttgtg cgacgtgttc gtcaatgacg
     8701 cgttcggcac cgcgcaccgc gcccaagctt cgaccgaagc cgtcgctcaa gccgcgcccg
     8761 ttgcctgcgc cggcgtattg atggcgggcg aactcgacgc tttgggcaaa gccctgaaac
     8821 agcccgcgcg cccgatggtt gccatcgttg ccggcagcaa agtgtccacc aagctgacca
     8881 tcctcgaatc gctggcggat aaagttgacc aactcatcgt cggcggcggt atcgccaaca
     8941 ccttcctgtt ggcggaaggt aaagccatcg gcaaatcttt ggcggaacac gatttggtgg
     9001 aagaatccaa aaaaattatg gcgaaaatgg cggccaaagg cggttctgtg ccgctgccga
     9061 ccgatgtcgt cgttgccaaa gcctttgccg ccgatgccga agcggtcgtg aaagacattg
     9121 ccgacgttgc cgaagacgat atgattttgg acatcggtcc gaaatccgcc gccgagcttg
     9181 ccgaactgct caaagccgca ggcacggtcg tttggaacgg ccctgtcggc gtgtttgagt
     9241 ttgaccaatt cgcaggcggc acgaaagctc ttgccgaagc cattgcccaa agcaaagcat
     9301 tctcgattgc aggcggtggc gacacgctgg cggcgattgc taaattcggc gttaccgacc
     9361 aaatcggcta tatttctacc ggcggaggcg cgtttcttga gttcttggaa ggtaaagagt
     9421 tgcctgccgt agccgctttg gaaaaacgcg gcgcgtaagc ggtttgatat aaaaaatgcc
     9481 gtctgaaacg ttgtgctgtt tctgacggca tttttgtgtg gcgattattg tgctttggct
     9541 gcccattccg ccggagtggc ggcaaccgaa atggaaagtg cgtgcagttc gttactttcc
     9601 agttgggctt tgagtccgtc tttaatcagg cggtggcgcg cgaggcgtgc cttgccttca
     9661 aattctgatg aaacgatgac ggcgaaaaaa tggtgtccgt cgccttctac tttgatatgt
     9721 tcgcattttg ccacgtcttc aatcatggct tttacttgtt ccggggtcag catggtaggt
     9781 tccttgttgg aaaaatgcgc cattatactg gcaaattgaa atgccgtctg aaacgggttc
     9841 agacggcatt tttgacggtg ttttattttt tggctttgaa gccgagcagg tgctgggtgg
     9901 tggcaagcca cgcgccgaat acgcccaacg cgatgacgaa gccgaacacc agcacgattt
     9961 cttcagggta aaagaaacgc cagccgatgt tcaagccgta gggtttgaaa atggcatcga
    10021 ccaatgggcg cacggcagag agcagccaac cgcaaagccc caagctgacg gcggcggaaa
    10081 ggatgctctg ccacattgcc tgataaagga aggggcggcg gataaacgac gcgggcgcgc
    10141 ccaagagttt ggtgatttcg atttcttctt ttcggctgag gatttgtagg cggatggtgt
    10201 tgtgcgcgac aaggacgaac gccatcccca gcgtcaggga aagaaaccat aaaattttgc
    10261 ggatgaactc gttgatttgg tacagcgttt gcacccattc ggtatccata gacgcggatt
    10321 cgaccatagg cagtttggta atgtctcggt agattgcctg catttgggcg ggcgtggttg
    10381 ccgggtcggg ggtaacgata aagacatccg gcagggggtt gccgtcaagc atggaaatca
    10441 gattttggtc gagattggac tgtaattctt ccagaccgtc ttctttgccg atgaagcgga
    10501 tgttgtcgag ccgtttgtcg cgcgccagca ggctgcgcac ggtatcgctg tcgctttgtg
    10561 cggcggcggt ttccatatag attgtgattt gcggcgactc gttgagtttg cccaacacgc
    10621 tttgcccgct ttggatgccc aaatacataa acagcggcag ggtcatggcg acggcgagca
    10681 ttatgagggt aagcagtgtg ccgaaaggtt ggcacagaag ctgtttgagc gcggtgcgcg
    10741 cggattcgac gtgcagcgag aggtagtgga tgatgctcat gcgagtcgtc ctttcgagag
    10801 gcgcaggatg cggtgtccgt agtccgccat cagggtttcg tcatgtgcgg cgacgatgac
    10861 ggttgttccc gcttcgtgga aggttttgaa caattccata atatcgagcg cgtaggcgcg
    10921 gtcgaggttg gcggagggtt cgtcggcaat cagcaggccg ggctggtgaa cgacggcgcg
    10981 ggcgatgcac aggcgttgtt gttcaccgcc ggagagggtt acgggatcgt ccaattctcg
    11041 tcctttcagg ccgacttttt cgatggcgat gcgggcacgc tcttcggctt tgcgcggcgg
    11101 atagccgata atccgaagcg gcaggatgac gttttgcagg acgttgcggt cgtagaggat
    11161 tttgtggtct tggaacacga tgccgatgtg ttggcgcata aagccgattt ggttgtcgga
    11221 caatgtgccg aggtcctgcc cgttaaacag gattttgccc ctgcttggtt tggtaatgcc
    11281 cgaaatcagc ttgaggacgg tggatttgcc cgaaccggag tgtcccgcga taaatatcat
    11341 ttcgcctttg ttgatttgga agctgacgtt tttcagggct tcaaaaccgc cgggataggt
    11401 tttggaaact tgttcgaaac ggatcatagg aggtcctgta aggaatgggc ggcatatcgt
    11461 ttcgggcggt tgcgtccgca gggatatgcc gtctgaacaa taggtaagac agtgccgatt
    11521 ataaagattc cgcctgtttt tagatagtgg ataagtttgg cggataccga aggtcgggcg
    11581 ggaaaaatgc cgtctgaagc ggattcagac ggcatccggc gtttaacggc attttgaatg
    11641 ggcgagtttg acggcttcgg tcaggctttt ttcgttcact tccccggtaa tggtctgcct
    11701 gtatccgcat ttcggtgctt cgacgacggt aaagggcagt acgccgacag tgtttccgta
    11761 ggttttcata aagtttcggc tgttcgcccc agtgtaacgc caaatcgggt aagaaacagg
    11821 ggtttgcttg aggaagttgc cgatattgtc ggatgtgtcg agcgcgatgc cgaccatatc
    11881 gacgctgcct tttttctgcg ctttgtacca tttggacatg gcaggcatct cttttcggca
    11941 cggaccgcac caggtcgccc aaaggttgac gatgcggacg ggggctttga gcgattgcag
    12001 gctttgcgcg gcaccgtctt tccatccggc cagttcgtct gccgaggcgg tatgtgcggc
    12061 aaatgtggcg ccaagggtga ttgcggcaag attcaagtat ttcatcgttt tgtcctttgt
    12121 atgtcgattc gggtattgta aaccgtttgg tacggttgta ggcgggatat tgagtaaaac
    12181 cctgtgtaag ccgataataa ggggattgtc gagaagtaag gaaatgtcat gtctgaaatc
    12241 aaaattttcc acaatccgcg ttgcagcaaa tcgcgtgccg ccttgtccct attggaagaa
    12301 cgcggcattg ctgccgaagt ggtcaaatat ttggatacgc cgcccgactt gtccgaattg
    12361 aaggatattt tcaacaaatt gggcttggag tcggcgcgcg ggatgatgcg tgtgaaagat
    12421 gatttgtaca aggaattggg tttggacaac cccgatttgg acaataacgc actgctgcgt
    12481 gccatcgccg atcatcccgc cctgttggag cgtccgattg ttttggcaaa cggtaaggcg
    12541 gctgtcggca ggccgttgga aaatatcgaa gcggtattgt gaacaaacgg ctgttttgca
    12601 gccgcaacgg cttgcgctat tacctgttgg gcggtttctg tttgagtgtt tttccgcttt
    12661 tgctggtgtt tacctcatcc gtttgggcgg tttatcggac gggcgggcag gttttgccgc
    12721 cgtatgtccg ggcggatgcc gcgctggtgt tgggtgccgc cgcatgggac aaacgccctt
    12781 cccctgtttt tcgggaacgc atcaaccacg ccatcgcgct ttaccaaagc cgcagggtag
    12841 gcaaaatcgt gtttacggga gggcgaacca aaaaaggcta tatgaccgaa gccgaggtcg
    12901 ggcggcggta cgcgctcaaa cagggggttc cggcgcgcaa catcctgttt gaaaacactt
    12961 cgcgcaacac ttatgaaaac ctgaacaaca tccgtccggt tttgcgtgcc aacggtattg
    13021 ccagcgtggt gattgtcagc gatccctacc atttggcgcg ggcggcggaa atggcggagg
    13081 atttgggtgt ccgcgtttat atgtctgcca ccccgaccac gcggtttgat gcgggaaata
    13141 agaaaaaaat ctttatgctg caagagggat atgcgttatc cctctaccgt ttggaaaaat
    13201 ggggcagccg ctttttggga tggctgtctg attgaagcgg tagaaaatgc cgtctgaaac
    13261 ttatccgcag gcagggttcg gacggcattt ttaatgccca agcacggtaa aaacagtaaa
    13321 ataagccgtt ttaaagattt tggagccatc atgaccgtca aaacccgttt cgcccccagc
    13381 ccaaccggct acctgcacat cggcggcgta cgcaccgccc tgttttcttg ggcgtttgcc
    13441 cgccatcata aaggcgaatt cttattgcgc atcgaagaca ccgacttggc gcgctctact
    13501 gccgaatccg tcaacatcat cctcgacggc atgaaatggg tcggactcga ttacgacaac
    13561 gccggcaacg tcgtgtacca aacccgccgt ttcgaccgct ataaagaagt catcgccgaa
    13621 cttttagaaa aaggcgatgc ctactactgc tattgcagca aagaagagtt ggaagccatg
    13681 cgcgagaaag ccgaaaaaga aggcacggcg acttacgacc gccgctggcg gccggaagca
    13741 ggcaaaaccc tgcccgaaat ccctgccggc gtgcaacccg tcgtccgctt caaaacgcct
    13801 ttggatggcg taaccaagtg gacggacttg gtcaaaggcg aaatctccat ccccaacgaa
    13861 gcactcgacg acctgattat cgcccgcgcc gacggcacgc cgacctacaa cttctgcgtt
    13921 gtcgtggacg actacgacat gggcgttacc cacgttatcc ggggcgacga ccatgtgaac
    13981 aacaccccga aacaaatcaa catcttaaaa gccatcggcg ctaccctgcc tgaatacggc
    14041 cacctgccga tgattcttaa cgaacaaggc aaaaaaatct ccaaacgcag cggcgatacc
    14101 gttgccatta ccgatttcgg cgcgatgggc atcctgcccg aagccatgct caactatctg
    14161 gcacgtttgg gctgggcgca cggcgacgat gagttcttca cgatggaaca atttatcgaa
    14221 tggtttgatt tgaaagacgt ttctccatct ccaagccgca tggatttgaa gaaactctac
    14281 tggatcaacg gcgaacacat caaaatcacg cccaacggca aactcgccga actcgtcaaa
    14341 ccgcgtctcg ctctgcgcga tatccatgaa actgaaaaac ctgcattgga agacgtgttg
    14401 gcactggtca aagaccgcgc ccaagacctg aacacacttg ccgacgagtg cctctacttc
    14461 tacgtcaaac aaacgcctac tgaagcggac gtgcagaaac actgggacga tgaagccgcc
    14521 gcccgtatgc tgcgctttgc cgaacgcctc gaagggctgg aagactggaa tgccgaagcc
    14581 atccacgacc tcttcaaacc cttctgcgac gaagaaggca ttaaaatggg caaactcggc
    14641 atgcccctgc gccttgccgt ctgcggtacg gcgaaaaccc ccagcgtcga tgctgtgttg
    14701 gcattaatcg gcaaagaaga agtgttgaaa cgcatccgcg cttaagttat ccacaggcgt
    14761 gggcgatgcc gtctgatgtc ggaatgcggc ttcagacagc attcaaacgg aagttgaaca
    14821 tgaaaaaaat attgtatttt ctgatgtttg ttttttctac aagcgtatgg gccggggatg
    14881 cggaagacaa tctgctcagc atccaatccg gctatcgtgc cttactgcaa aaacaaaaca
    14941 atctggacgg aaaaatcatc gggatgcagt cggatttgga agatgcgcgc cggcgtttgc
    15001 agacggctca agcagacatc gcccgtttgg aagcggaaat tcctgcagca atggcgcaaa
    15061 aagcccggca ggctgaagag ctgaggcaaa tcggagtgcg tttggactat gcttggaatg
    15121 cggtttacgg cgcaggggga acgaaagcgt cggggaattg accgatgaat tccctctttg
    15181 tggacaatac tgttttcatt acacggctga aagccgggca tatcggcagg ttggttcagg
    15241 cgttgtttga ggagtggcac ggatttgaac cgtggtcttc tgtggataag attcatgcct
    15301 attacggcag gtgtttgaag gatgacgaac tgccgctggc atttgcggct gtggatgatt
    15361 tcggaaccct gttgggttcg gctgcggtca agcggcatga tatggaaagt tttccacagt
    15421 atgaatattg gttgggtgat gtctttgttt tacctgaata tcgcggaaaa ggcattggca
    15481 ggaggctggt cgcccactgc ataggcgcag cgcgttcgct ggggataaag ttcttgtatc
    15541 tttatacgcc tgatgtgcaa atattttatg aatcattcgg ctgggcggtt gtcgggcgac
    15601 atttccataa cggtgaatgg gttacggtta tgcgtttgga tatggataag gtttaagccg
    15661 aatggacaaa tgccgtctga gctgttcgga cggcattttt atgtttggaa acttcttgtc
    15721 agataatgtt tatccacaga tttttccata tggtttgatg ctgttccgac aacggaaatt
    15781 aagatacgga tttgcacaaa tctttcagac ggtacagttc tgacaatgct tcgcgcgggg
    15841 tcaggctgtc gggatcgagt ttttccaagg ctgctgccaa tataccttca aaatgttttt
    15901 cctctgcttt atccacaaag ttgcccacat tcggttcatc tcctttttca gacggcatgg
    15961 tactgaaaat atccagttgg ggacggttcg cggcggcttg gttttccagt ccgttcaaat
    16021 gcttttgggc ggatttcaat gcgcgtacag gcaggccggc gagtttggca acggcgatgc
    16081 cgtagctttt tccggcggga ccgggttgga tttggtgcag aaacacgatg tcctgtccct
    16141 gttcgagcgc ggaaaggtgc atattgagtg cggcggcgtg ggcttcgggc aggtaggtca
    16201 gctcgaaata gtgggtggca aacaggctga aggatttgtt tttttgcagc aggtgttcgg
    16261 caacggcgtg cgcgagggcg aggccgtcga aagtggaagt gccacgtccg acttcgtcca
    16321 ttaaaacaag gctttgttcg gtggcgtgat gcaggatgta ggcagtttcg ctcatttcga
    16381 ccatgaaggt ggagcggttg gaggcgaggt cgtccgatgc gccgatgcgg gtgaagattt
    16441 gatcgatggg cccgattgtg gcggcatcgg caggcacgaa acagccggtg tgtgccaata
    16501 aaacaatcag cgcgacttgg cgcatgtagg tggatttgcc gcccatattg gggccggtga
    16561 gcagcatgag gcggtgtttg tggtcaaggt cggtgtggtt ggcggtgaag tggcgtacct
    16621 gctgttcgac aacgggatgg cggccgtttt cgatgtggat aaccggatag tcggcaaact
    16681 cggggcggac gaagttccgc tcttttgcca aggctgaaaa tgtggacaat acgtccagcg
    16741 cggcggcggc tttggcggct ttttgaagct gcggcaatgc cgtctgaagg tttttcaata
    16801 cgccgtcaaa gagttgtttt tctaaggcga gggcttgctc ttgagcagtc agtactttgt
    16861 cttcaaaggc tttcagttcc ggcgtgatga agcgttcggc gtttttgagg gtttgccggc
    16921 gttggtagtc ggcaggtgct tgttcggctt gggttttgga caattcaatg taaaagccgt
    16981 gaacgcggtt gaactcgact ttgagtgtgg acaaaccggt acgttcgcgt tccttggctt
    17041 ccaaatccag caaaaattcg tcgccatggt tttgaatgcg gcgcaattcg tccagttcgg
    17101 gatgaaaacc gtggttgatg acattgccgt cttttagcca gacggaaggt tcgggcaaaa
    17161 tggcttggcg gagctgttcg gctgtggata ggttttccgg gaaaacggct ttgagggttt
    17221 ccaacaggct gctgccgttt gtggacaagt cgatttctga cagggcaaac aggctgtcgc
    17281 gcagggcggc gaggtcgcgc gggcgggcgt tgccgacggc gatgcgggca gcaatgcgtt
    17341 caatgtccgc aatgtttttc agacggcatt ggaggggttc gtattggctg tccagcgcgg
    17401 ttacagcttc ttggcgggcg cggatgtggg cgcggttgcg caaagggtgg tgcagccaga
    17461 gagccaagag gcggctgccc atgtgggtgg tgcaaaggtc gagcgtggac atcagggtcg
    17521 gcgatttttt gccggagagg gtttgcgtga tttcgagatt gcggcgcgtg gcggcatcca
    17581 taccgatata ttggctgtcg gtttcgagcg acaggccgtc caagtgttgc ggcatcaggt
    17641 tttgcgtcag gcggatatag ttcaacagtg cacctgccgc gccaatcgca acggcgtgtt
    17701 ctttgccatc caaaccgaag ccgcgcaaat cctggcagcc gaaatattcc gtcagcagtt
    17761 tttcccccgc gtcggcggca aactgccacg cgttcaggcg cgtaacaccc gatgccgtct
    17821 gaagttgcgg tgcgttttta ctgtcaggca acagaatttc cgccgcctgc aggcgcgcca
    17881 gttcgtcgtc caatttatcc acagtcgtca gcttggtttt gaattcgccg ctttgcagcg
    17941 atgcccacgc caaaccgatg tattttttgt cgggggacac ggcaacgatg cggttggttt
    18001 ccttgtcttc cagcaatgcg gaatcggtta gcgtgccagg cgttacgatg cgcacgactt
    18061 tgcgttccac cggccctttg cctgcgccga cttcgccgac ctgttcgcaa atcgccacgc
    18121 ttttgcccaa cttgaccagg cgcgccagat attgttcggc ggcgtgaaac ggcacgcctg
    18181 ccattttaat cggtacgccg tccatctgcc cgcgcgtggt cagggtaata tccaaaagtt
    18241 ttgccgcttc taccgcatcg tcgaaaaaca tctcgtaaaa atcgcccata cggtaaaaca
    18301 ccagtttgtc ggtatgttgc gctttgatgc cgaggtattg ctgcatcatt ggggaaacgg
    18361 cggatttgga catggggctg ccttatcatt aggaaaacgg tattgtagca aaaggttttg
    18421 tcttcgacgg aatgagactg accgtaagcc tgtcaataaa gttgtggaga caagtaggaa
    18481 aacagcaaag ttatccacag gaatattatt aagtcaaaaa acatccacgt ttatctgtcc
    18541 tatacggcaa gccttaaact caaacttatt tgacgaaaag gtaatgaaaa tattggatat
    18601 ttgcaactta tacacaagca gatccgcaat catcaaaatc atcattaaaa ttttaaattc
    18661 aaatattgat ggtaaaagtt ttggaaatct gtgcaaacag taaaattcat ctatatcaaa
    18721 taagcatcaa gtagttagat gtaatagtgg aatgtaactt tatttcagaa tacaatacag
    18781 atattgaaat ttcgtttcac agcttggagt atatacatga gcattaaagt agcgattaac
    18841 ggtttcggcc gcatcggccg cctcgcattg cgtcaaattg aaaaagccca cggcatcgaa
    18901 gtcgtcgctg tcaacgacct gacccctgcc gaaatgctgc tgcacctttt caaatacgac
    18961 agcacgcaag gccgtttcca aggtactgcc gaattaaaag acgatgccat cgtggtaaac
    19021 ggcaaagaaa tcaaagtttt cgccaatccg aatcccgaag aattgccttg gggcgagttg
    19081 ggtgtggatg tcgtcctcga atgtaccggc ttctttacca ataaaaccaa agccgaagca
    19141 cacatcaggg ccggcgcgcg caaagtcgtg atttccgcac ccagcggcaa tgatgtgaaa
    19201 accgtcgtat atggcgtgaa ccaagacatt ttggacggca gcgaaaccgt tatctccgct
    19261 gcttcctgca ccaccaactg ccttgccccg atggcggcag tcctgcaaaa ggaattcggc
    19321 gtagtcgaag gcctgatgac caccatccac gcctacacca gcgaccaaaa cacccttgac
    19381 gcgccgcacc gcaaaggcga tttgcgccgc gcccgcgccg ccgcgctcaa catcgtgccc
    19441 aacagcaccg gcgccgccaa ggccatcggt ctggttatcc ctgaattgaa cggcaaactc
    19501 gacggctccg cccaacgcgt ccctgttgcc accggctcgc tgaccgaatt ggtttccgtc
    19561 ctcgaacgcc ctgtaaccaa agaagaaatc aacgccgcga tgaaagcagc cgccagcgaa
    19621 tcttacggct acaacgaaga tcaaatcgtt tcttccgacg ttgtcggcat cgaatacggc
    19681 tcgctcttcg atgcgaccca aacccgcgtg atgaccgtgg gcggcaaaca attggtgaaa
    19741 accgttgcct ggtacgacaa cgaaatgtcc tacacctgcc aactcgtccg cactttggaa
    19801 tactttgcag gcaaaatcta aggcttgaac aaacctgtgg ataagtaaat gccgtctgaa
    19861 cacattgcgt tcagacggca ttgtttatct gtatagtgga ttaaatttaa accagtacgg
    19921 cgttacctcg ccttgccgta ctatttgtac tgtctgcggc ttcgttgcct tgtcctgat
//
LOCUS       DAXISH010000039        19556 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.039, whole genome shotgun sequence.
ACCESSION   DAXISH010000039 DAXISH010000000
VERSION     DAXISH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 19556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19556
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.039"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(596..751)
                     /locus_tag="ACFOV4_001344"
     CDS             complement(596..751)
                     /locus_tag="ACFOV4_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619346.1"
                     /translation="MPSERLQTAFFTQFPPFSIIPDNTVILKFVIPAQAGIQSVRFRF
                     FEVSGNF"
     gene            complement(769..3519)
                     /gene="tbpA"
                     /locus_tag="ACFOV4_001345"
     CDS             complement(769..3519)
                     /gene="tbpA"
                     /locus_tag="ACFOV4_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein TbpA"
                     /protein_id="HFC7619347.1"
                     /translation="MQQQHLFRLNILCLSLMTALPVYAENVQAGQAQEKQLDTIQVKA
                     KKQKTRRDNEVTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIR
                     GMDKNRVSLTVDGLAQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSV
                     EQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEA
                     LLIHTGRRAGEIRAHEDAGRGVQSFNRLVPVEDDHKYAHFVVKEECPNGYAACKDKPK
                     KDIVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFENKRHYIGGILEHTQ
                     QTFDTRDMTVPAFLTKAVFDANKKQAGSLRGNGKYAGNHKYGGLFTNGENGALVGAEY
                     GTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQGIGLDNHFQQTHCSADGS
                     DKNCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDTAKIRHNLSVNLGFDRFGSN
                     LRHQDYYFQNAKRAYSLKTPPKNGNGGSNPNPNGDKDKPYWVSIGGGNVVTGQICLFG
                     NNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRT
                     LSWNAGIVLKPADWLDLTYRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAG
                     IVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKDGKEEAKGDPAYLNAQSARITGINIL
                     GKIDWNGVWDKLPEGWYSTFAYNRVHVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGY
                     DQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYT
                     IKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEM
                     KF"
     gene            complement(3606..5750)
                     /locus_tag="ACFOV4_001346"
     CDS             complement(3606..5750)
                     /locus_tag="ACFOV4_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="HFC7619348.1"
                     /translation="MNNPLVNQAAMVLPVFLLSACLGGGGSFDLDSVDTEAPRPAPKY
                     QDVSSEKPKAQKDQGGYGFAMRFKRRFWLPRGKEDEVKLKESDWEETGLPDDPKNLPK
                     RQKSVIDEVKTDDGSNNIHSSPYLMQSNHQNGSTNGGANQPKNEVTDYKDFKYVYSGW
                     FYKHAKSEIKRENGSSSAKSGDDGYIFYHGEKPSRQLPASEKVIYKGVWHFVTDTKRG
                     QKFNDILGTSKGQGDKYSGFSGDDDEQYSNKNEKTLQGGQEGYGFTSNLEVDFGNKKL
                     KGNLIRNNRVTNATTGEKHTTQYYSLEAQVTGNRFSGTATATDKPEKDGTKQHPFVSD
                     SSSLSGGFFGPKGEELGFRFLSDDKKVAVVGSAKTQDKPENGAAALGGAGAAASGGVA
                     AMPSENGKLTTVLDAVELTHGGTAIKNLDNFSNAAQLVVDGIMIPLLPEASESGNNQA
                     NQGTNGGTAFTYKTTYTPKSDEKDTQAQTGTGGTQTASGTESVNGGQAGTKTYAVEVC
                     CSNLNYLKYGLLTRKTAGNTGEGGNGSPTAAQTAQGAQSMFLQGERTDENKIPSEQNV
                     VYRGSWYGHIANGTSWSGNASNATSGNKADFTVNFGEKKITGTLTAENRQQATFTIEG
                     MIQGNGFSGTAKTADSGFDLDQSNTTGTPKAYITNAKVQGGFYGPKAEELGGWFAYPG
                     DKQAQPSASGSGASAANSATVVFGAKRQQLVQ"
     gene            complement(6543..7355)
                     /gene="murI"
                     /locus_tag="ACFOV4_001347"
     CDS             complement(6543..7355)
                     /gene="murI"
                     /locus_tag="ACFOV4_001347"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFC7619349.1"
                     /translation="MENIGRQRPIGVFDSGIGGLTNVRALMERLPMENIIYFGDTARV
                     PYGTKSKATIENFSMQIVDFLLEHDVKAMVIACNTIAAVAGQKIRQKTGNMPVLDVIS
                     AGAKAALATTRNNKIGIIATNTTVNSNAYARAIHRSNPDTLVRTQAAPLLVPLVEEGW
                     LEHEVTRLTVCEYLKPLLADGIDTLVLGCTHFPLLKPLIGREAGNVALVDSAITTAEE
                     TARVLAQEGLLNTDNNNPDYRFYVSDIPLKFRTIGERFLGRTMEQIEMVSLG"
     gene            7545..8006
                     /gene="tsaE"
                     /locus_tag="ACFOV4_001348"
     CDS             7545..8006
                     /gene="tsaE"
                     /locus_tag="ACFOV4_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFC7619350.1"
                     /translation="MPDFPPVSRFLADEAATLDLGAAWSSRLNAPLVIYLEGDLGAGK
                     TTLTRGILRGLGHQGAVKSPTYAIVESYPLERFTLHHFDLYRFSFPEEWEDAGLDELF
                     AANSVCLIEWPQQGGEFTPPADITATLTHDGGGRKCLLTAHTERGRESLPL"
     gene            8003..9253
                     /locus_tag="ACFOV4_001349"
     CDS             8003..9253
                     /locus_tag="ACFOV4_001349"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFC7619351.1"
                     /translation="MTKLTRRQIIRRTAGTLFALSPIASAVAKTVRAPQFTAARIWPS
                     HTYTRLTLESTTALKYQHFALDNPGRLVVDIQNANINTVLHGLSQKVMADDPFIRSIR
                     AGQNTPDTVRLVIDLKQPSYAQVFSLPPVGGFKNRLVVDLYPQGMDADDPMMALLNGS
                     PNKTRRGSPEADLAQNTTPQPGRGRNGRRPVIMIDPGHGGEDPGAVSPGGLQEKHVVL
                     SIARETKKQLEALGYNVFMTRNEDVFIPLGVRVAKGRARRADVFVSIHADAFTSPSAR
                     GTGVYMLNTKGATSSAAKFLEQTQNNADAVGGVPTSGNRNVDTALLDMTQTATLRDSR
                     KLGKLVLEELGRLNHLHKGRVDEANFAVLRAPDMPSILVETAFLSNPAEEKLLGSESF
                     RRQCAQSIASGVQRYINTSVLKRG"
     gene            9333..10151
                     /locus_tag="ACFOV4_001350"
     CDS             9333..10151
                     /locus_tag="ACFOV4_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFC7619352.1"
                     /translation="MKGMDKLRYQQDFLNIRPIFTAGEQEYLTELSDRLPLSVLTDSV
                     RNIEEIGIDFVYSSAKLEGNTYNQYDTQALLKLGQTAGGKLYSDAVMLINLRESYRHL
                     LSGLDSPDPFDWLDFLKTTHSLISENLLEKGSGGVVRRDSVTISGTDYTPLSNPQSLD
                     TELKWLLQEAPKIENPFDRAVYLHNNLAYLQYFKDCNKRTARNCMTLSLMRSGFFPCV
                     FAPDSYPAYAEAVVAYYETGDYGLFKKYFISAYENTVNKYGPQPDMDIFRNFSL"
     gene            complement(10452..11594)
                     /locus_tag="ACFOV4_001351"
     CDS             complement(10452..11594)
                     /locus_tag="ACFOV4_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFC7619353.1"
                     /translation="MNTLYTLFATCPRGLETVLSQELESLGCTDVQVFDGGVSCRGGL
                     EQVYAANLHSRTASRILLRLTKGTYRNERDIYKLAKNINWFNWFTLQQTFKVKVEAKR
                     ANVKSIQFVGLTVKDAVCDAFRDIYDARPSVDKAAPDVRIHAFLDERNVEIFIDTSGE
                     ALFKRGYRLDTGEAPLRENLAAGLLLSAGYDGTQPFQDPFCGSGTIAIEAAWIAARRA
                     PGMMRRFGFEKLQNFDKTLWSDLRRRAEAQVKPAFAPISGSDSDRRIIQTALANARSA
                     GVDDIVSFSVADAQSVRPNGVGGIMVSNPPYGVRLEEVRALQALYPQLGTWLKKYYAG
                     WLAAMFTGDREMPKFMRLSPKRKIPLYNGNLDCRLFLIDMVQGSNR"
     gene            complement(11643..12065)
                     /locus_tag="ACFOV4_001352"
     CDS             complement(11643..12065)
                     /locus_tag="ACFOV4_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619354.1"
                     /translation="MNKNRKLLLAALLLIAFAAVKLVLLQWWQAQQPQAVAAQCDLTE
                     GCTLPDGSRVRAAAVSTKKPFDIYIEHAPAGTEQVSISFSMKNMDMGFNRYMFERQPS
                     GTWQAVRIRLPICVEGRRDFTADITIGSRTFQTAFTAE"
     gene            complement(12058..12867)
                     /locus_tag="ACFOV4_001353"
     CDS             complement(12058..12867)
                     /locus_tag="ACFOV4_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFC7619355.1"
                     /translation="MIQDTRPLIRVVAGILLNRDGDYLLSSRPEGKPYAGYWEFAGGK
                     VEAGETDFQALQREFEEELGIRILAATPWLTKIHSYEHARVCLKFLWVNPGQWTGEPQ
                     SREGQAWSWQKAGDFTVAPMLPANGALLRSLSVPRRLYGSLKTGLHGENSMGAYRVLP
                     LGSAEESGANVLMEAAQWQDRPEHADSVWMMVQTREQWRQAQEKGADVVVWRVCNDVQ
                     AQEAAEALRQGVSVPLVLAANGQTVARYGKLWLGLGAHVVVRDETIGKNHE"
     gene            complement(12949..13326)
                     /gene="acpS"
                     /locus_tag="ACFOV4_001354"
     CDS             complement(12949..13326)
                     /gene="acpS"
                     /locus_tag="ACFOV4_001354"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFC7619356.1"
                     /translation="MIYGIGTDIVSLKRIIRLNKKFGQAFAVRILTPEELLEFPQAGK
                     PVNYLAKRFAAKEAFAKAVGTGIRGAVSFRNIGIGHDALGKPEFFYGPALSKWLEEQG
                     ISRVSLSMSDEEDTVLAFVVAEK"
     gene            complement(13517..14284)
                     /locus_tag="ACFOV4_001355"
     CDS             complement(13517..14284)
                     /locus_tag="ACFOV4_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013107841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFC7619357.1"
                     /translation="MQEIMQSIVFVAAAILHGITGMGFPMLGTTALAFIMPLSKVVAL
                     VALPSLLMSLLVLCSNNKKGFWQEIVYYLKTYKLLAIGSVVGSILGVKLLLIPPVSWL
                     LLLMAIITLYYSVNGILNVCAKAKNIQVVANNKNMILFGFLAGIIGGSTNAMSPILLI
                     FLLSETENKNRIAKSSNLCYLLAKIVQIYMLRDQYWLLNKSEYGLIFLLSVLSVIGLY
                     VGIRLRTKISPNFFKMLIFIVLLVLALKIGHSGLIKL"
     gene            complement(14294..14833)
                     /locus_tag="ACFOV4_001356"
                     /pseudo
     CDS             complement(14294..14833)
                     /locus_tag="ACFOV4_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261815.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TauD/TfdA family dioxygenase"
     gene            complement(15005..15226)
                     /locus_tag="ACFOV4_001357"
                     /pseudo
     CDS             complement(15005..15226)
                     /locus_tag="ACFOV4_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261815.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="taurine catabolism dioxygenase TauD"
     gene            complement(15225..15332)
                     /locus_tag="ACFOV4_001358"
                     /pseudo
     CDS             complement(15225..15332)
                     /locus_tag="ACFOV4_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(15378..16106)
                     /gene="pdxJ"
                     /locus_tag="ACFOV4_001359"
     CDS             complement(15378..16106)
                     /gene="pdxJ"
                     /locus_tag="ACFOV4_001359"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HFC7619358.1"
                     /translation="MLLGVNIDHIATVRNARGTTYPSPVEAALVAETHGADLITMHLR
                     EDRRHIKDADVFAVKNAIRTRLNLEMALTEEMLENALKVMPEDVCIVPEKRQEITTEG
                     GLDVLAQQDKIAEFTKILTDAGIRVSLFIDADDRQIQAARDVGAPVVELHTGAYADAR
                     SHAEQIRQFERLQNGAHFASDLGLVVNAGHGLTIHNVTPIAQILAIRELNIGHSLISQ
                     ALFLGLPEAVRQMKEAMFRARLLP"
     gene            complement(16130..16921)
                     /gene="recO"
                     /locus_tag="ACFOV4_001360"
     CDS             complement(16130..16921)
                     /gene="recO"
                     /locus_tag="ACFOV4_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFC7619359.1"
                     /translation="MSEHRVNHEPVFLLASSPWRESSLRVEAFSRRYGRVALLARSAR
                     KRQSELRGVLVPFVPVSASWYGSQELKTLHRAEWIGGWPQPQGRALFSGLYVNELMLK
                     LTVREDPLPELYDALAEVMEAVCCKAAYIDDLRRFEWRLLNLLGVAPDLNRDGDGGTI
                     AAGGTYLVRPETAVFPVGKGFAVPPHAAGVVAPGQSLIDLREGSFRTAESLQQALKIT
                     RLFIRHLLPEGLKSRQVLEQIRQFDRKETARETVPTSDGTASNAV"
     gene            complement(16955..18082)
                     /gene="pheA"
                     /locus_tag="ACFOV4_001361"
     CDS             complement(16955..18082)
                     /gene="pheA"
                     /locus_tag="ACFOV4_001361"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFC7619360.1"
                     /translation="MLECTINYCSGEIMSQTIDELLLPHRNAIDTIDAEILRLLNERA
                     QHAHAIGELKGTGAVYRPEREVAVLRRIQDLNKGPLPDESVARLFREVMSECLAVERP
                     LTIAYLGPQGTFTQQAAIKHFGHAAHTMACPTIDNCFKQVETRQADYLVAPVENSTEG
                     SVGRTLDLLAVTALQACGEVVLRIHHNLLRKNNGSTEGIAKVFSHAQALAQCNDWLGR
                     HLPNAERIAVSSNAEAARLVAESDDGTVAAIAGRTAAEIYGLDMVAECIEDEPNNTTR
                     FLVMGHHETGASSSDKTSLAVSAPNRAGAVASLLQPLTESGISMTKFESRPSKSVLWE
                     YLFFIDIEGHRRDAQIQTALERLGERASFVKVIGSYPTAVL"
     gene            complement(18121..19353)
                     /locus_tag="ACFOV4_001362"
     CDS             complement(18121..19353)
                     /locus_tag="ACFOV4_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HFC7619361.1"
                     /translation="MPSAHYPEMSEKLMAVLMAMLVTLMPFSIDAYLPAIPEMAQSLN
                     ADVHRIEQSLSLFMFGTAFGQVVGGSVSDIKGRKPVALTGLAVYCLAVAAIVFASSAE
                     QLLNLRVVQAFGAGMTVVIVGAMVRDYYSGRKAAQMFALIGIILMVVPLVAPMVGALL
                     QGLGGWQAIFVFLAAYSLVLLGLVQYFLPKPAVGGKIGRDVFGLVAGRFKRVLKTRAA
                     MGYLFFQAFSFGSMFAFLTESSFVYQQLYRVTPHQYAWAFALNIITMMFFNRVTAWRL
                     KTGVHPQSILLWGIVVQFAANLSQLAAVLFFGLPPFWLLVACVMFSVGTQGLVGANTQ
                     ACFMSYFKEEGGSANAVLGVFQSLIGAGVGMAATFLHDGSATVMAATMTASTSCGIAL
                     LWLCSHRAWKENGQSEYL"
BASE COUNT         4473 a         5278 c         4941 g         4864 t
ORIGIN      
        1 acggaaacct gcaccacgtc attcccacga aagtgggaat ccagtttttt gagtttcagt
       61 cattttcaat aaattgcctt agtattgaat gtctagattc ccgcctgcgc gggaatgacg
      121 ggatttgaga ttgcggcatt tatcgggagc aacagaagcc gctctgccgt cattcccacg
      181 aaagtgggaa tccagttttt tgagtttcag tcatttccga taaattgcct tagcattgaa
      241 tgtctggatt cccgcctgcg cgggaatgac gggatttgag attacagtgt atcgagaagg
      301 atgggaaacg gtgggaattg tgtaaaaaat gccgtctgaa gcctttcaga cggcatttgc
      361 ggcattcgga catttaaaaa ccccatcatt cccgcgcagg agggaatccg aatacatccg
      421 aacagaaacc tgcatcccgt cattcccgcg aaagcgggaa tctagaacgt aaaatctaaa
      481 gaaaccgttt tatccgataa gtttccgcac cgacaggtct agattcccac tttcgcggga
      541 atgacgggat ttgaggtttc tgtttttgat tttccgcctt cgcgggaatg acggtttaga
      601 agttacccga aacctcaaaa aaccgaaacc gaacggactg gattcccgcc tgcgcgggaa
      661 tgacgaattt caagattacg gtattgtcgg ggatgatgga aaacggtgga aattgtgtaa
      721 aaaatgccgt ctgaagcctt tcagacggca tttgcggcgt ttggacgttt aaaacttcat
      781 ttccaagcta aatgtgtagt tgcgaccggg ggcggcatat cggttgtaaa cgccgacatt
      841 tttgtgttga ttgactgcgc cgccggcagt ttgccgcaca ttttcccaag taacatagcg
      901 gtagttgagg aggttgtaca cgcccgcacg gagggtgaag tgttttttaa tcgtgtaata
      961 accggacaca tccacaatat accaagggcg ggtacggcgc gcggtggctt ttgtattgcg
     1021 gctgttgccg ttgagcaaag cccggctgcc caacaactct gtgatttcct tggctttgga
     1081 ataagtcagc ataccgttca caccccattt gccttccggt tggtcatagc ccaagccgac
     1141 gacatagcgc gagggttgga tggcatcaaa caggtgtgat tgaatatcgg tgcggtctgc
     1201 gcgttttttg atgtcgcgga catggacacg attataggca aatgtagaat accaaccttc
     1261 gggcaattta tcccatacgc cgttccaatc gattttgccc aaaatattga tgccggtaat
     1321 ccgcgcgctt tgggcattga ggtaagccgg gtcgcctttg gcttcttctt tgccgtcttt
     1381 aatttgcgct tcataacccc ggacaatcaa atcgcggtag gcattgttga accaacttgc
     1441 ctccaagttg ccgaaatcgc ctttaaacac gatgccggct tctttgttga acgatttttc
     1501 cggatcgatt ttgaccgcct tgctttgaac acccgcccgc cagccgtaca tttccgcaaa
     1561 cgaaggcagg cggaagccgg ttgaagtgcg gtaagtcaaa tccagccagt cggcaggttt
     1621 gaggacgatg cctgcgttcc aggacagggt gcggtgcgtg ccggtggaaa cgctgccgtc
     1681 gtccgaatgc gtgctgcggt agtcgtagcg caagcccgcg ccgacatccg cccacctgcc
     1741 caaacggaca ttgtcccgaa ctgccgcgta atagcttttg ccgttgatgc tgcgcggcgt
     1801 gcagtccgta taagtattgt tgccaaagag gcagatttgc cccgtaacca catttccccc
     1861 gcctatgctg acccaatagg gtttgtcctt gtcgccgttg gggttggggt ttgagccgcc
     1921 gttgccgttt ttagggggcg ttttcaacga ataggcgcgt ttggcatttt gaaaataata
     1981 atcctgatgg cggagattag agccaaagcg gtcaaacccg agattcacgc tcaggttgtg
     2041 gcggattttg gcggtatcga aggatttttt gaatgccgcc tgcaagagcc tgtggctttc
     2101 cccgtaaatc acgcggtcgg atttgtaata ggaaaacggc ttgtcggcac tcggacggca
     2161 atttttgtcc gaaccgtcgg cagaacagtg cgtctgctga aaatgattgt ccaaaccgat
     2221 gccctgccgg tcgtaagaga ggcgggcata atccgcccaa gtgtctttat cggcattggt
     2281 atagacatat tccaaaccgt agcggctttt ggtgtgcgtc tcgtcgtaaa acacgcccgt
     2341 accgtattcc gcgcccacca gcgcaccgtt ttcgccgttg gtaaacagtc cgccgtattt
     2401 gtggttgccc gcgtatttgc cgttgccgcg caaagaaccc gcctgttttt tatttgcatc
     2461 aaaaaccgcc ttggtcagga atgccggaac cgtcatatcg cgcgtgtcga aagtttgttg
     2521 cgtgtgttcg agtatgccgc cgatgtagtg ccgtttgttt tcaaaacgaa aacccgggcg
     2581 gaacagccac gaccggcttt cgtatgaaag cggatcggcg aggaagcgat tgggacccgt
     2641 gtagtctcgg gtggaaaccg tttgacgttc gtctttgccg acaatatctt ttttcggttt
     2701 gtctttacaa gccgcatatc cattagggca ttcttctttg accacgaaat gagcgtattt
     2761 gtggtcgtct tcaaccggca ccagcctgtt gaagctctga acgccgcgtc cggcatcttc
     2821 gtgggcgcgg atttcccccg cgcgccgacc cgtgtggatc agcaaagcct ccgcaccgcc
     2881 gatgcgcccc gccagcgcga tggattgggt aagcccccgg tttttgccgg aataggcggt
     2941 tttactctga atcccccact gcctgccttc cccgataaca tcgtcggcgg ttttggtttg
     3001 aaatgcgacc gaacccgcca atgcgccgct gccttgttcg accgagtttg agcctttgct
     3061 gatttcgaca gccttgacgt tttcatactc gatttcattg attgcgccgc tgctgcccgc
     3121 cgtcctcgtc ccgcccaatg ccgcctgcgc ggtgtaggac tgtatttgcg ccaagccgtc
     3181 taccgttaag gaaacgcggt ttttgtccat accgcgtatc gagtaacccg agcttgcgcc
     3241 gcgcccctgt tcgacgacgg cgatgccggg gtcgtaacgc gtcaggtcgc ggatgtcgag
     3301 tacctgttcc ttgctgaggg tgtcggcggt tttaaccaat ttgcccagcc cggttacttc
     3361 gttatcacgg cgggttttct gttttttggc ttttacctgt atggtatcca actgtttttc
     3421 ctgtgcttgt ccggcttgca cattttctgc ataaacgggc agcgcagtca ttaaagacag
     3481 gcataaaata tttaatcgga acaaatgttg ctgttgcata gtgtttccct actcttcgct
     3541 ttcagacggc atcggaagga gcgatgccgt ctgaagcctt attctcgatt gttcggcagc
     3601 cgtgcttatt gcacaagctg ttggcgtttc gcaccgaata ccacggtcgc gctgttggcg
     3661 gctgatgcgc ctgaccccga agcggacggc tgcgcctgct tgtcgcccgg ataggcaaac
     3721 catccgccca actcttcggc tttgggcccg taaaaaccgc cctgcacctt ggcgtttgtg
     3781 atatatgcct taggcgtacc ggtggtattg ctctgatcga gatcaaagcc tgagtcagca
     3841 gtttttgccg taccggaaaa accgttgccc tgaatcattc cctcaatggt aaaggttgcc
     3901 tgctgcctgt tttcagcggt taacgtgccg gtaatttttt tctcgccaaa attcacggta
     3961 aagtccgcct tgttgccact cgttgcattg gaagcattgc cgctccagct tgtgccgttg
     4021 gcaatatgcc cgtaccaaga cccccgataa acgacgtttt gctcgcttgg aatcttgttt
     4081 tcatcggtgc gctcgccttg gaggaacata ctttgtgcac cctgtgccgt ttgggcggcg
     4141 gttgggctgc cgttgccgcc ttcccccgta ttgccggcag tcttgcgcgt cagcaacccg
     4201 tatttcagat aattgaggtt ggaacagcag acttcgactg catatgtttt cgttcctgcc
     4261 tgcccgccgt taacgctctc agtacccgaa gcggtttgcg tgccgcccgt gcctgtttgg
     4321 gcttgggtgt ctttttcatc gcttttcggc gtgtaggttg ttttgtaggt aaaggctgtt
     4381 ccgccgtttg taccttgatt ggcttgattg ttcccacttt cggaagcctc gggcaggagc
     4441 ggaatcataa tgccgtcgac aaccagttgg gcggcgttgc tgaagttgtc gagatttttg
     4501 attgctgtgc cgccgtgcgt cagctcgacc gcatccaaaa ccgtggtcag cttaccgttt
     4561 tcagacggca tagctgccac accgcccgat gctgccgcac ctgcgccgcc taaagccgcc
     4621 gcgccatttt ccggtttgtc ttgggttttc gcgctgccga caacggcaac ttttttatcg
     4681 tcgctcaaaa agcggaaacc caattcctca cccttcgggc cgaaaaagcc gccgctcaaa
     4741 gaagacgagt cggaaacaaa gggatgttgt ttggttccgt ctttttcagg tttgtcagtt
     4801 gccgttgccg tgccgctgaa acggttgcct gttacttgag cctcaaggct gtaatattgg
     4861 gtggtatgtt tttcgccagt agtagcgttt gtaactctat tattgcgtat taaattaccc
     4921 ttcaattttt tattgccgaa atccacttct aaatttgagg taaaaccata accctcttga
     4981 ccgccttgta aagtcttttc atttttatta gaatattgtt catcatcatc gcccgaaaat
     5041 ccgctgtact tatctccttg tccttttgag gttccaagaa tatcgttaaa tttttgtccc
     5101 cttttagtat cggttacaaa atgccatacg cctttgtaga taactttttc agaagcggga
     5161 agttgtcggg aaggtttttc accgtgataa aagatatagc cgtcgtcgcc agattttgca
     5221 ctgcttgacc cgttttctct tttgatttcg cttttcgcgt gtttgtaaaa ccagccggaa
     5281 taaacatatt taaaatcttt ataatctgtt acttcgtttt ttggttggtt tgcaccgcca
     5341 ttagtgctgc cgttttgatg gtttgattgc atgagataag gggaagaatg aatattattg
     5401 ctgccatcgt ctgtttttac ttcatcaata accgatttct gtcgcttagg taagtttttg
     5461 ggatcgtcag gtaatcccgt ctcctcccaa tcactctctt tcagtttaac ctcgtcttct
     5521 tttccccgcg gcaaccagaa ccgccgcttg aagcgcatcg cgaaaccgta tccgccttgg
     5581 tctttttggg ctttaggctt ttcggaagaa acatcttgat attttggcgc gggacgcggg
     5641 gcttcggtat cgacagaatc aagatcgaaa ctgccgcctc cgcccaaaca agcactcaac
     5701 aaaaacaccg gcagcaccat agcagcctga ttcaccaatg gattgttcat ataaacccaa
     5761 ttcaattaaa gaatgataag gattattatt ttatttattt ttaacaaatt tgcaaatact
     5821 tttttatttt tttagtaaat acaccaaaat cccgttattc ccgcgcagtc gtgaatccga
     5881 acgcgtccgc acggaagcct atatcccgtc attcccacgt atatcccgtc attcccacga
     5941 aagtgggaat ccggttcgtt cggtctcgct tgttttaagt ttcgggtaac ttccacttcg
     6001 tcattcccgc gcaggcggga atccagtttt ttgagtttca gtcattcccg ataaattgcc
     6061 ttagcattga atgtctagat tcccgcctgc gcgggaatga cgggatttga ggtttctgtt
     6121 tttgattttc tgttttcgta ggaatgacgg tttagagtta cccgaaacct caaaaaaaaa
     6181 cctaaaccga acggactgga ttcctgcctg cgcgggaatg acgggtttcg agattacagt
     6241 gtatcgagaa ggatgggaaa cggtgggaat tgtgtaaaaa atgccgtctg aagcctttca
     6301 gacggcattt gcggcattcg gacatttaaa aatcccatca ttcccgcgca ggagggaatc
     6361 cgaatacatc tgcacagaaa cctgcatccc gtcattcccg cgaaagcggg aatctagaac
     6421 gtaaaatcta aagaaaccgt tttatccgat aagtttccgc accgacaggt ctagattccc
     6481 actttcgtgg gaatgacggg attttaggtc tctgtaatct cgggcagctt tccgtcatcg
     6541 ttttaaccca aagacaccat ttcaatctgc tccatcgtcc tgcccagaaa acgctcgccg
     6601 atggttctga atttcaaagg aatatcgctg acataaaaac gatagtcggg attgttgttg
     6661 tcggtattga gcaatccttc ctgagcaagg acgcgtgcgg tttcttcggc agtcgtaatc
     6721 gcggaatcga ccagcgcgac attgcccgcc tccctgccga ttaagggctt gagcaaggga
     6781 aagtgcgtgc agcccaacac cagcgtatcg atgccgtctg caagcaatgg tttgaggtat
     6841 tcgcatacgg tcaggcgggt aacttcatgt tccaaccaac cttcctccac caaagggacg
     6901 agcagcggcg cggcctgcgt gcggacgagc gtgtcggggt tgctcctgtg gatggcgcgt
     6961 gcataagcat tgctgttgac tgtcgtattg gtggcgataa tgccgatttt gttgttgcgc
     7021 gtggttgcta gcgcggcttt cgcgccggcg gaaatcacgt ccaacacagg catattgccc
     7081 gtcttttgac ggattttctg ccccgccacc gccgcaatcg tattacacgc gataaccatc
     7141 gccttaacat cgtgttccag cagaaaatcg acaatctgca tcgagaaatt ttcgatggtc
     7201 gccttagatt tcgtcccgta aggcacgcgc gccgtatcgc cgaaataaat gatgttctcc
     7261 atcggcagcc gctccatcag cgcgcgcaca ttggtcaaac cgccgattcc cgagtcaaaa
     7321 acgccgatgg gtcgctgcct gccgatattt tccatccttt ttccaatccg tcctaaacat
     7381 acaatccgcg tattgtacac gcgccgcttt ttcttgacag ccgttgccgt ctgaaagcag
     7441 gatgcggatt tggctgttat aatgtacggc aatgccgccg ccgggcaccc ggttttccgg
     7501 ccgcctgccc ctccgatccg ccacataaaa gttgtaaagc ccctatgcct gattttcctc
     7561 ccgtttcccg attccttgcc gacgaagccg ccacactcga tttgggtgcg gcgtggtctt
     7621 cccgtttaaa cgcaccgctg gtcatttacc tcgaagggga tttgggtgcg gggaaaacca
     7681 cgctgacacg cggcatcctg cgcggattgg gtcatcaggg cgcagtcaaa agcccgacct
     7741 acgccatcgt cgaatcttat ccgctggaac gtttcacgct gcatcatttc gacctctacc
     7801 gcttctcgtt ccccgaagaa tgggaagacg cggggcttga cgaactgttt gccgcaaaca
     7861 gcgtctgcct gatcgaatgg ccgcaacagg gcggggaatt tacgccgccc gccgacatca
     7921 ccgcaacatt gacacacgac ggcggaggca gaaaatgcct gctgaccgcc cataccgaac
     7981 gaggacgcga aagcctgccg ctatgaccaa actgacacga agacaaatca tccgccgcac
     8041 cgccggcaca ctgttcgccc taagccccat cgcatccgcc gttgccaaaa ccgtgcgcgc
     8101 accacaattc accgccgcac ggatatggcc gtcgcacacc tacacccgcc tgacgctgga
     8161 aagcacaacc gcgctcaaat accagcactt cgcgctcgac aacccgggca ggctggtcgt
     8221 cgacatacaa aacgcaaaca tcaataccgt attgcacgga ctgtctcaga aggttatggc
     8281 ggacgacccc tttatccgca gcatacgcgc gggtcagaac acgcccgaca ccgtccgcct
     8341 cgtcatcgat ttgaaacagc cttcctacgc gcaagttttt tccctccccc ccgtcggcgg
     8401 ctttaaaaac cgcctcgtcg tcgatctcta tccgcaaggg atggatgccg acgatccgat
     8461 gatggcgctg cttaacggca gcccgaacaa aacccggcgc ggctctccgg aagccgacct
     8521 cgcccaaaac accacgcccc aacccgggcg cggcagaaac gggcgcaggc ccgtcattat
     8581 gatcgacccc ggacacggcg gcgaagaccc cggcgccgtc agcccgggcg gcttgcagga
     8641 aaaacacgtc gtcctctcca tcgcccgcga aaccaaaaaa caattggaag ccttgggtta
     8701 caacgtcttt atgacgcgca acgaagacgt gttcatccca ttgggcgtgc gtgtcgccaa
     8761 agggcgcgca cggcgggcgg acgtatttgt ctccatccac gccgatgcct tcaccagccc
     8821 ctccgcgcgc ggcacggggg tttatatgtt aaacaccaaa ggcgcgacca gctctgccgc
     8881 caaattcttg gaacagacgc aaaacaatgc cgacgcggtc ggcggcgtac cgaccagcgg
     8941 caaccgcaat gtcgataccg ccctgctcga tatgacccaa accgccacgc tgcgcgacag
     9001 ccgcaaactc ggcaaactgg tgcttgaaga attgggcagg ctcaaccatc tgcacaaagg
     9061 cagggtggac gaagccaatt tcgccgtttt gcgcgcaccc gatatgccgt ctatcctggt
     9121 cgaaaccgcc ttcctgtcca atcctgccga agagaagctg ctgggcagcg aatccttccg
     9181 ccggcagtgc gcccaatcca ttgcctcggg tgtccaacgc tacatcaaca cttccgtatt
     9241 gaagcggggt tgattgaaaa ggcggtgttt caatatagtt gtcggatgaa ggcaggcata
     9301 aacctacttc cgccccaaac cgcgttttta tgatgaaagg tatggataaa ttgagatacc
     9361 aacaggattt tttaaatatc cgccccattt ttacagccgg cgaacaagaa tacctgaccg
     9421 aattgtccga tcggcttcct ttatctgttt taacggactc cgtgcgtaat attgaagaaa
     9481 tcggtatcga ttttgtgtac agttctgcca aattggaagg aaacacttat aatcaatacg
     9541 atacgcaggc attgcttaaa ctcgggcaaa ccgcaggcgg gaagttatat tcggatgccg
     9601 taatgttaat caacctgagg gaaagttacc ggcacctgct gtccggtttg gacagccccg
     9661 atccgtttga ctggttggat ttcttaaaaa ccacccacag cctgatttcg gaaaacttac
     9721 tggaaaaagg ctccggcggc gtagtccgcc gcgacagcgt taccataagc gggacagact
     9781 acacgccttt atccaacccg caaagtttgg atacggaatt aaaatggttg cttcaagaag
     9841 cccccaaaat agaaaatccc ttcgaccgcg ccgtttatct ccataataat ttggcgtatc
     9901 ttcaatattt taaagattgc aataaacgta ctgccagaaa ctgtatgacc ttgtcgctga
     9961 tgcgctccgg tttttttcct tgcgtattcg cccccgacag ttatcccgcc tatgccgagg
    10021 ctgtcgtagc ctattacgaa accggcgatt acggtttatt caagaaatat tttatttcgg
    10081 catacgaaaa taccgtaaat aagtacggcc cacagcctga tatggatatt ttccgcaact
    10141 tctcccttta attccaaggg gttgttatcc gtatcttccg cacgcggcaa atgcggcggc
    10201 acagtggaca cacccctccc ttaccttcgg ttatagtgaa ttaacaaaaa ccagtacggc
    10261 gttgcctcgc cttagctcaa agagaacgat tctctaaggt gctgaagcac caagtgaatc
    10321 ggttccgtac tatttgtact gtctgcggct tcgtcgcctt gtcctgattt ttgttaatcc
    10381 actataatat cggccggata ttaaaaaaag ccgtctgaac atttttcaga cggcattttt
    10441 gtacactttc ctcaacggtt cgatccctgc accatatcaa tcaggaacag gcggcaatcg
    10501 aggttgccgt tataaagcgg aattttgcgt tttggcgaca ggcgcatgaa tttgggcatt
    10561 tcccgatctc cggtaaacat tgccgccaac cagcctgcgt aatatttctt caaccacgtc
    10621 cccaactgcg gataaagcgc ctgcaaggcg cggacttcct caaggcgcac gccgtagggc
    10681 ggattggaca ccataatgcc gcccacgccg ttcggacgga cggattgcgc gtcggcaacg
    10741 ctgaaggaaa cgatgtcgtc caccccggca ctgcgtgcgt tggccaatgc cgtctgaatg
    10801 atgcggcggt cgctgtcgct gcccgaaatc ggtgcaaaag ccggtttaac ctgcgcttcg
    10861 gcacggcggc gcaaatccga ccacagcgtt ttatcgaaat tttgcagttt ttcaaaaccg
    10921 aaacggcgca tcatacccgg cgcgcggcgg gcggcaatcc aagcggcttc gatagcaatc
    10981 gtgccgctgc cgcaaaacgg gtcttgaaac ggctgcgtgc cgtcgtagcc tgccgagagc
    11041 agcaatccgg cggcaaggtt ttcgcgcagc ggggcttcgc cggtatcgag acggtagccg
    11101 cgtttgaaca gggcttcgcc cgaagtgtcg atgaagattt cgacattgcg ttcgtccaaa
    11161 aaggcgtgga tgcgaacatc gggcgcggct ttgtccacgc tcggacgtgc gtcgtaaatg
    11221 tcgcggaaag cgtcgcagac ggcatctttg acggtcagtc cgacaaattg gatgctctta
    11281 acgttggcac gctttgcctc gactttgact ttgaacgtct gctgtaaagt aaaccaatta
    11341 aaccagttga tatttttggc gagtttgtag atgtcgcgct cattgcggta tgtccctttg
    11401 gtcaggcgca gcaggatacg gctggcagta cgcgaatgca ggttggcggc gtaaacctgt
    11461 tccaatccgc cccggcagga aacgccgccg tcaaacactt gtacatcggt acagccgagg
    11521 ctttcgagtt cttgagataa aacggtctcc aagccgcgcg ggcaggtggc gaaaagtgta
    11581 tataaagtat tcataacgtg tcctttccgg acggatgttc cggcaatggc ggattgaaag
    11641 gtttattcgg cggtaaatgc cgtctgaaat gtccgactgc cgattgtaat gtccgccgta
    11701 aaatcgcgcc tgccttcgac acagatgggc aggcggatgc gtactgcctg ccaagtcccc
    11761 gacggttgcc gctcgaacat atagcggttg aaacccatat ccatattttt catactgaag
    11821 ctgatgctga cctgttccgt gccggcgggc gcgtgttcga tataaatatc aaacggtttt
    11881 ttggttgaaa cggcggcggc gcggacgcgg cttccgtccg gcagcgtgca accctcggtc
    11941 aaatcgcatt gcgccgccac agcttgcggc tgctgcgcct gccaccattg caacaaaacg
    12001 agcttgacgg cggcaaaggc aatcagcagc agtgcggcaa gcagtaattt acggttttta
    12061 ttcatgattc ttccctattg tttcatccct taccaccacg tgcgccccca atccgagcca
    12121 tagttttcca taacgtgcaa ccgtctgtcc gtttgctgca agtacgagcg gcacggatac
    12181 gccctgccgc agggcttctg ccgcctcttg tgcctgaaca tcattgcaca cgcgccacac
    12241 gacaacatcc gcgccctttt cctgcgcctg ccgccattgt tcgcgggtct gcaccatcat
    12301 ccacacgctg tcggcgtgtt cgggtctgtc ctgccattgc gccgcctcca tcaaaacgtt
    12361 cgcaccgctt tcctctgccg aacccaaagg caggacgcgg tacgcgccca tactgttctc
    12421 cccgtgcaaa cccgttttca ggctgccgta caaacggcgc gggacggaca gcgaacgcaa
    12481 aagcgcgccg ttggcaggca gcatgggggc aacggtaaaa tcacccgcct tctgccacga
    12541 ccatgcctgt ccttcgcgcg attgcggttc gcccgtccat tggccggggt ttacccatag
    12601 gaatttcagg cagacgcggg cgtgttcgta ggaatggatt ttggtcagcc aaggcgtggc
    12661 ggcgaggatg cggatgccga gttcttcttc aaactcgcgt tgcaaggctt ggaagtcggt
    12721 ttctcccgct tcgaccttgc cgccggcaaa ttcccaatat ccggcatagg gtttgccttc
    12781 ggggcgcgag ctgagcaggt agtcgccgtc tcggttgagc aggatgccgg caacgacgcg
    12841 gataaggggt cgggtgtctt gaatcatggc gggtacgcgg ttggtcggtc ggagtgcaaa
    12901 tgagggacga gcaatgccgt caacgggttt gccgcatttc agacggcatt atttttcggc
    12961 aacgacaaac gccaatacgg tgtcttcttc gtcgctcatg ctgaggctga cgcggctgat
    13021 gccttgttcc tccagccatt tggacagggc ggggccgtag aaaaattcgg gcttgcccaa
    13081 tgcgtcatgc ccgatgccga tgttgcggaa ggaaaccgcg ccgcgtatgc ccgtgccgac
    13141 ggctttggca aaggcttctt tggcggcaaa gcgtttggca aggtagttga cgggtttgcc
    13201 cgcctgagga aattcaagca gctcttccgg agtgaggata cgcacggcaa acgcctgtcc
    13261 gaattttttg tttaagcgga tgatgcgctt gagggaaacg atgtctgtac cgatgccgta
    13321 aatcatattt gcgctccttc gcccttggtt gcgggtagtg atgatgaatg ccgtcaattt
    13381 cttggggcgt taaaatggcg tgaatatcca ctttcggggt tttgtcggta acaattttta
    13441 ttgtaacctt ttgcatttga aattctaaaa catcgtgcca attatttaat aaggagttaa
    13501 ggcatttaat aatgaattaa agtttgatta aacccgaatg cccgattttc agagccaata
    13561 ccaataaaac aataaaaatt aacattttaa aaaaatttgg gctaatctta gtccttaacc
    13621 gaattccaac atacaatcca ataacagaca atacggacag taaaaatatt aaaccgtatt
    13681 cactcttatt taataaccaa tactggtctc ttagcatata tatttgaaca attttcgcca
    13741 aaagatagca tagattgctt gattttgcga tacgattttt attctctgtt tcgctaagca
    13801 aaaatattaa caatatggga gacatggcat tggttgaacc gccgatgatg cctgccaaaa
    13861 acccaaaaag aatcatattc ttattattgg caactacttg aatatttttt gcttttgcac
    13921 atacatttaa aataccatta acagaataat acaatgtaat gattgccatc agtaaaagca
    13981 gccacgacac tggaggtatc aaaagcaact tcacccccaa aatgctgcca acgacgctgc
    14041 cgatagcaag caatttatag gtttttaaat aataaacaat ctcttgccaa aaaccctttt
    14101 tgttattgct gcatagaacc aacaagctca ttaacaggct tggtaatgcc accaaggcaa
    14161 caaccttaga caatggcatg ataaaagcca atgcggttgt accgagcatc ggaaatccca
    14221 tgcctgtaat tccgtgcagt attgcggcag caacaaaaac gatagattgc attatttctt
    14281 gcataaccgt cctttataca gtaattcttg ctctaatata atgcctgttt ttatccgtat
    14341 aatcagttct ggcatgcaag ccattgacat tgtcaataat aatcaaacca tcatcttgtg
    14401 cagaaaattc ttgaatatca ctcgcatttt ttataacatt tataagataa tcaagtgcaa
    14461 gtaccatttc ctttgatact ttatttctat tttcttcaat acctttatag atacaatcac
    14521 ttctaaatct aatcatttga gtattgaccg ataagatatt accccatctc acaccttgtt
    14581 ttttatcaaa tgatgctggt gttttaaatg gatataaatt gcccgttaat gtttttaagt
    14641 gttttttacc ggtttctgtt ttagataact gattgacaat atctgatgaa cttaaaaata
    14701 gggaattacc tccatcattg gctgatttta ctacatacat aaccaaataa ctttccgggt
    14761 tttcactaaa agatgaatca ctatgaagtg gacattctcc aacatcttcc gagaaagtta
    14821 tatcattatt tatagtggat taacaaaaac cagtacggcg ttgcctcgcc ttagctcaaa
    14881 gagaacgatt ctctaaggtg ctgaagcacc aagtgaatcg gttccgtact atctgtactg
    14941 tctgcagctt cgtcgccttg tcctgatttt tgttaatcca ctatattaca taatcatcgc
    15001 ctcaatattt aatatcccaa aatatagatt taaaaccatc gcctttgtgg tttgtcagca
    15061 ttcctaattg agatagaaag tcaaataatt tcttgtttct ccggctgcca tcaagatggt
    15121 ttagattaag acctcgaaca atacaatacc caatacgctg tactgtattg tgaatttctt
    15181 ctatcaaact attattgttt gcagataaaa tatacttttg attcatatag tgaattaaat
    15241 ttaaaccagt acggcgttgg cttgccttgc cgtactattt gtactgtctg cggcttcgcc
    15301 gccttgtcct gatttaaatt taatccacta taacatatcc ctgtcgtgaa atgctgtctg
    15361 aaagggtttg cctgccctta cggcagcagc cttgccctga acatcgcctc cttcatttgg
    15421 cgcacggcct cgggcaatcc gaggaaaagt gcctgcgaaa tcagcgaatg cccgatgttc
    15481 agttcgcgga tggcgaggat ttgggcgatg ggggtaacgt tgtgtatggt cagtccgtgt
    15541 ccggcgttga cgaccaagcc caaatcgctg gcaaaatgcg cgccgttttg cagacgctcg
    15601 aactgcctga tttgttcggc gtggctgcgc gcgtcggcat acgcgcctgt gtgcagctcg
    15661 acaacgggcg cgccgacatc acgggcggct tggatttgcc tgtcgtcggc atcgataaac
    15721 aaggacacgc gtatgcccgc atcggtcagg attttggtga attcggcaat tttgtcttgt
    15781 tgcgccaata cgtccaagcc gccttcggtc gtgatttcct gacgtttttc aggcacgatg
    15841 cacacgtctt ccggcatcac tttaagcgcg ttttcgagca tttcttccgt caacgccatt
    15901 tcaaggttca ggcgcgtgcg gatggcgttt ttgacggcaa acacatccgc gtctttgatg
    15961 tggcggcggt cttcgcgaag gtgcatggta atcaggtccg caccgtgcgt ttcggcaacc
    16021 agtgccgcct ccacggggct gggataagtc gtgccgcgcg cgttgcggac ggtggcgatg
    16081 tggtcgatgt tgacacctaa aagcataatc tttcctttta tttctgcctt cagacggcat
    16141 ttgaagccgt gccgtccgaa gtcgggacgg tttcccgggc ggtttctttg cggtcaaact
    16201 gccgtatctg ttccaacacc tgccgcgatt tcagcccctc gggcaacagg tggcggataa
    16261 aaagccgtgt gattttcaat gcctgttgca ggctttcggc ggtgcggaaa ctgccttcgc
    16321 gcaaatcgat caggctctgc ccgggggcga caacgccggc ggcgtgcggc ggtacggcaa
    16381 atccttttcc gacggggaag acggctgttt ccgggcggac aaggtatgtg ccgcctgccg
    16441 caatcgtccc gccgtccccg tcgcggttca aatcgggggc aacgcccaac aggttcagca
    16501 gccgccactc gaaacggcgc aagtcgtcga tataagcggc tttgcagcac accgcctcca
    16561 tcacttccgc caacgcgtcg tataactcgg gcaacggatc ttcgcggacg gtcaacttca
    16621 gcatcaactc gttcacatac aatccgctga acaacgccct accctgcggc tgcggccacc
    16681 cgcctatcca ttcggcgcga tgtagggtct tcaactcttg cgaaccatac caagacgcac
    16741 tcaccggcac aaacggcacc aacacgccgc gcaattcgct ctgccgtttg cgcgcgcttc
    16801 ttgccaaaag tgccacacgc ccgtaacggc ggctgaacgc ttcgacccgc aggctgcttt
    16861 cgcgccaggg cgaggaagcc aacaggaaga cgggttcgtg gttgactcgg tgttcggaca
    16921 tcatgcctga aatgccgtct gaacgctgcc gccgctacaa aacggcggtc gggtacgaac
    16981 cgatgacttt gacgaacgaa gcgcgttcgc ccaagcgttc caatgccgtc tgaatctgcg
    17041 cgtcccggcg gtgtccttcg atgtcgatga agaacaggta ttcccacaaa acggatttac
    17101 tcggacggct ctcaaacttg gtcatggaaa tacccgactc agtcagcggt tgcagcagcg
    17161 aggcaaccgc gcctgcccgg ttgggcgcgg aaacggccag cgaagtcttg tcgctgctgc
    17221 ttgcaccggt ttcgtgatgt cccatcacca agaagcgcgt ggtgttgttc ggttcgtctt
    17281 cgatgcactc ggcaaccata tcgagtccgt agatttccgc cgccgtgcgt ccggcgatgg
    17341 cggcaaccgt accgtcgtcc gattcggcaa ccagccttgc ggcttcggca ttgctggaca
    17401 cggcaatccg ttcggcgttg ggcaggtgtc tgcccaacca gtcgttgcac tgcgccaacg
    17461 cctgcgcgtg ggaaaagact ttggcaatgc cttcggtgct gccgttgttt ttacgcaaaa
    17521 ggttgtggtg gatgcgcaaa acgacttcgc cgcacgcctg caacgcggta acggcaagca
    17581 aatccaacgt gcgcccgacc gagccttcgg tcgagttttc cacgggggcg accagatagt
    17641 ctgcctgacg ggtttcaacc tgcttgaagc agttgtctat ggtcggacac gccatggtgt
    17701 gcgcggcgtg tccgaaatgc ttaatcgccg cctgctgggt aaacgtgccc tgcggcccca
    17761 gataggcgat ggtcagcggg cgttctacgg cgaggcactc gctcatcact tcccgaaaca
    17821 ggcgtgctac cgattcgtcg ggcagcgggc ctttgttcaa atcctgaatg cggcgcaaca
    17881 cggcgacttc gcgttcggga cggtacactg cgcccgtgcc tttcagttcg ccgatggcgt
    17941 gtgcgtgttg cgcgcgttcg ttgagcaggc gcaggatttc cgcatcaatg gtgtcgatgg
    18001 cgttgcggtg gggaaggagg agttcgtcga tagtttggga cataatttcg cctgaacagt
    18061 aatttatcgt gcattctaac atcaaatgcc gtctgaaacg gtttcagacg gcattttccg
    18121 ttaaaggtat tcgctttgcc cgttttcttt ccacgcacga tgcgagcaga gccacagaag
    18181 cgcaatgccg caagaggtgg acgcggtcat cgttgccgcc atcacggttg ccgaaccgtc
    18241 gtgcaagaag gtcgccgcca tacccacccc cgcgccgatt aaagattgga atacacccaa
    18301 tacggcgttt gcgctgccgc cctcttcttt gaaataggac ataaaacacg cctgcgtgtt
    18361 tgcaccgacc aagccctgcg taccgacgga aaacatcacg cacgcgacca gcagccaaaa
    18421 cgggggcaac ccgaaaaaca gcacggcggc gagttgggac aggttggcgg caaactggac
    18481 gacaatcccc catagcagga tgctttgcgg atgcacgccg gttttgagcc gccacgcggt
    18541 aacgcggttg aaaaacatca tcgtgatgat gtttagtgca aacgcccaag cgtattgatg
    18601 aggcgtaaca cggtagagct gctggtacac gaaggaagat tcggtcagaa aggcgaacat
    18661 cgaaccgaag ctgaatgcct gaaaaaacag ataacccatc gcggcacggg ttttcaatac
    18721 gcgcttgaac cgccccgcca ccagcccgaa cacgtcccgt ccgattttgc cgccgacggc
    18781 gggcttgggc aggaaatact gtaccaaacc gagcagcacc agcgaatacg ccgccagaaa
    18841 aacaaaaatc gcctgccagc cacccaagcc ctgcaacaat gcgccgacca tgggtgcgac
    18901 cagcggcaca accatcaaaa tgatgccgat aagggcaaac atctgggcgg ctttgcgtcc
    18961 ggaataataa tcgcgcacca ttgcgccgac gatgaccaca gtcatgcccg caccgaatgc
    19021 ctgcacgacg cgcaggttga ggagctgttc ggcactcgaa gcaaatacga tggcggcaac
    19081 ggcaaggcag tagacggcca gtccggtcag cgcgacgggt ttgcgccctt tgatgtcgga
    19141 caccgaaccg ccgaccacct gtccgaacgc cgtgccgaac ataaacaaac tcaaactctg
    19201 ttcgatgcgg tgaacatccg cgttcagcga ttgcgccatt tcgggaatcg cgggcaggta
    19261 ggcatcgatg gaaaacggca tcagcgtaac cagcatcgcc atcaaaaccg ccatcagttt
    19321 ttcgctcatt tcaggataat gggcagaagg cataaattct cgtccgattc gcaaacaaac
    19381 cgcccggcgg cggaaaacac aatacgcgga aacggaaaat tttaacacac cggcacaaac
    19441 aggcggcaac aaaagccccg gcaaaaccgg acgaaccgga acgatatagt ggattaacaa
    19501 aaaccagtac agcgttgcct tgccttagct caaagagaac gattctctaa ggtgct
//
LOCUS       DAXISH010000040        18927 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.040, whole genome shotgun sequence.
ACCESSION   DAXISH010000040 DAXISH010000000
VERSION     DAXISH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 18927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18927
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.040"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(269..481)
                     /locus_tag="ACFOV4_001363"
     CDS             complement(269..481)
                     /locus_tag="ACFOV4_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFC7619362.1"
                     /translation="MELGYTPYNLRTLRNRCKLTQAELAQIVGVKHYIQVGRWEAEPD
                     TETRRADMPLEKWRQFLDWTEKTNAV"
     gene            complement(493..774)
                     /locus_tag="ACFOV4_001364"
     CDS             complement(493..774)
                     /locus_tag="ACFOV4_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619363.1"
                     /translation="MNRAALFNRYPEWIIGQDGASRFITHCRYPRLIAKIHRQTDSEC
                     PGGHYRHSENGITLYDFIFFDGKPADEARFAAVLTETCRRAVKKICETK"
     gene            complement(821..1024)
                     /locus_tag="ACFOV4_001365"
     CDS             complement(821..1024)
                     /locus_tag="ACFOV4_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619364.1"
                     /translation="MNIIEQEMKHSSLRKVDAEIAKIIADAHKINAESVKIAQESRWY
                     PMMAATGLVTAIAAVLALIFKFA"
     gene            complement(1104..1676)
                     /locus_tag="ACFOV4_001366"
     CDS             complement(1104..1676)
                     /locus_tag="ACFOV4_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HFC7619365.1"
                     /translation="MGKPGKSSRPSALLSARWQDIDLTARLWHIPAADMKTKHPFTVP
                     LSDWAVEILRELHTQTGDNIHLFPGIRPRRKPAPHPDHISIKFAHNAIRRLGYDGSTP
                     GKSKHTMHGFRHLFTNISLTAGKDTLTTDLALGHISRAALQRAGFSSLHHYLTADSYR
                     LQERRELAEWYSRRHRQAYEAAAQNTCNKT"
     gene            complement(1651..1995)
                     /locus_tag="ACFOV4_001367"
                     /pseudo
     CDS             complement(1651..1995)
                     /locus_tag="ACFOV4_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701232.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(1988..2863)
                     /locus_tag="ACFOV4_001368"
     CDS             complement(1988..2863)
                     /locus_tag="ACFOV4_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3102 domain-containing protein"
                     /protein_id="HFC7619366.1"
                     /translation="MNTEIEIIATDKVSNQAAMRSVLVMEQWGNGETYSEERWVERGR
                     QAVRQTMEGMFELGRALIILKEHTEHGRFMEIVKSQFGLGIAETSRLMSATRRFATPQ
                     MQKAAPKLMDLGKSKLLELLVEEDVTLVGLAEGEEVNGMTFDDVDRMTVRELRVALRE
                     SRENLAAKDEVMKTKTAKIDELAEKLAKKQTVVREPKAEDVGSELAMQLTSLEVGIRS
                     QVSRLKDLFDQLNAHSEAHGISHQAKMVGTLNQIILDCEQLRESYALPTEAPTDNVPE
                     WLGGETGEGDESGND"
     gene            complement(2908..3198)
                     /locus_tag="ACFOV4_001369"
     CDS             complement(2908..3198)
                     /locus_tag="ACFOV4_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFC7619367.1"
                     /translation="MAESKRVQRLLRVFIALDEHPIIGLSNKDLSVGLGLTPSQVSRD
                     IDDLVASGLVIKLENGNYAYGIKTLQIAERFRQQHERLQSKIAEIGKRVDVD"
     gene            complement(3210..3413)
                     /locus_tag="ACFOV4_001370"
     CDS             complement(3210..3413)
                     /locus_tag="ACFOV4_001370"
                     /inference="COORDINATES: protein motif:HMM:TIGR04111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFC7619368.1"
                     /translation="MLSQWERAIYGYTVEKLKENFAQNGQTLAQWARENGFKPRDVYL
                     VVGGQRKGNYGKGHEIAKKLGLK"
     gene            3503..3880
                     /locus_tag="ACFOV4_001371"
     CDS             3503..3880
                     /locus_tag="ACFOV4_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC7619369.1"
                     /translation="MISKSLFGNRLKEKRKFLGLTQAQAAEKAGIERETWGKYERGVF
                     MPSGDVLLSFLNMGIDVSSLFAAEQGIRPSENSEISKEESELLGYYRQASDNGKFVIL
                     SVAKGAEKKAAENTQVSATHKTA"
     gene            3909..4154
                     /locus_tag="ACFOV4_001372"
     CDS             3909..4154
                     /locus_tag="ACFOV4_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619370.1"
                     /translation="MFDFEQQIKWGERAEEIVKEAATQNNIEIPEPLASALAKAVKVH
                     YLSQAGVFSLVEAYADTVNPTEKEVDYQAIGKELFEK"
     gene            4388..5356
                     /locus_tag="ACFOV4_001373"
     CDS             4388..5356
                     /locus_tag="ACFOV4_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619371.1"
                     /translation="MAKKTTKTIHYLRAQQNHSLFDLEVALRRVLSAAPTVQDTQIEQ
                     YNQLTQIMHRTLDPKDVKGNSIGGLLIHIGSGTKDEHIRTMSNRPVQQDDHGGTQAPP
                     SGYSFLRKEAFLYIVGHHVIFCGHGFLSASTVASYLSLLSNKLRENNPDIVQFNIEFK
                     AVGNCDKLSLIQQHGVKSILLDASAYQLSRNRLYQDSRSTIAKALGKVGSVFTSELSD
                     EELEAQSEIHINLEVLLNGNSRASIEAQSLMQEQAEEIIDDETVNQGFSITTQQGEVI
                     QPSDVKLSKSVRIGRYDEANSLLPDSAFTAISEYFLELQSRNLTEQ"
     gene            5353..5835
                     /locus_tag="ACFOV4_001374"
     CDS             5353..5835
                     /locus_tag="ACFOV4_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619372.1"
                     /translation="MKKYLPLLRFLLIACISAFLAWKGQPFVHGNEKAVDLIINVFAI
                     LAGFLIAIMTLFSDMRFDEDANWRQIQIREGVQEQRYIKHSLLFYTYLAVLVCVFIVI
                     LLAHKEEYKNGPAIFWLERSYLFLACISIFYSVFLPGNLIKSRKEEFKKLMEKKKPKI
                     "
     gene            5925..6428
                     /locus_tag="ACFOV4_001375"
     CDS             5925..6428
                     /locus_tag="ACFOV4_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HFC7619373.1"
                     /translation="MSDKFNQFINRVLSHEGGYANHPKDPGGETNWGITKRTAQANGY
                     NGSMRAMTREQAISIYRKAFWERYRADQMPEAVAFQFFDACVNHGYGNAARMLQRAAG
                     VPDDGIIGEISLKAINSLPENDLLLRFNAERLVFYTKLGTFTSFGKGWVRRVAQNLIH
                     AAADNAD"
     gene            6537..6869
                     /locus_tag="ACFOV4_001376"
     CDS             6537..6869
                     /locus_tag="ACFOV4_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619374.1"
                     /translation="MLDASPPQERGSRRETRSQKKASQITAFFRWLGGLVSNPATGKI
                     SHTKLWANVAAAAMTWKFVQAADAPEWLWWAYGAMVGGYALIKRGIAAVPQLAEVKKS
                     ANQEGGRQ"
     gene            6866..7276
                     /locus_tag="ACFOV4_001377"
     CDS             6866..7276
                     /locus_tag="ACFOV4_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="HFC7619375.1"
                     /translation="MIEFVRAKKRLLWAFVLLLVWTCGYRYAADKAEAEQTALIATYR
                     HSSMVAAEQYALQLKKAQDERQRWYDFSQKQGRKPVKKQYPPQTKKAGYLKTKEELLA
                     ELACLTAEMAALKKPDALIHGKEVRQKERNSSQG"
     gene            7281..7829
                     /locus_tag="ACFOV4_001378"
                     /pseudo
     CDS             7281..7829
                     /locus_tag="ACFOV4_001378"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            7845..8030
                     /locus_tag="ACFOV4_001379"
                     /pseudo
     CDS             7845..8030
                     /locus_tag="ACFOV4_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
     gene            complement(8347..8709)
                     /gene="ssrA"
                     /locus_tag="ACFOV4_001380"
     tmRNA           complement(8347..8709)
                     /gene="ssrA"
                     /locus_tag="ACFOV4_001380"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(8772..9377)
                     /locus_tag="ACFOV4_001381"
     CDS             complement(8772..9377)
                     /locus_tag="ACFOV4_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Smr/MutS family protein"
                     /protein_id="HFC7619376.1"
                     /translation="MNTDFQNILKQLGKQAQKEAAEKQAAEKNKQKQEQDFDFSQAVG
                     QVSPLKNRQQYYAPPDKTPIKVRPKDNRADEENYFYIGSTYNDPPASFSKNGQGKNDI
                     QRLKNGYYPVVTDVDLHGYTQEEAQKVLNEFIAFTQKRGVCGEIIHGSGLGSKGYKPV
                     LKNMTRNWLMQHPDVLAYAEPREGNDGCVRILLKRKLRQQD"
     gene            complement(9768..9953)
                     /locus_tag="ACFOV4_001382"
     CDS             complement(9768..9953)
                     /locus_tag="ACFOV4_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619377.1"
                     /translation="MPSEPPFRRHSTHQNRKTAPKIIITRHNGKPDTKPNTAAKMPSE
                     AVGATILIWGALHQRGA"
     gene            complement(9959..11014)
                     /locus_tag="ACFOV4_001383"
     CDS             complement(9959..11014)
                     /locus_tag="ACFOV4_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7619378.1"
                     /translation="MKTYAPALYTAALLTACSPAADSNHPSGQNAPANTESDGKNITL
                     LNASYDVARDFYKEYNPLFIKTYQSEHPGTSVSIQQSHGGSSKQALSVANGLQADVVT
                     MNQSSDIDLLEKKGLVEKGWQQALPDHAAPYTSTMVFLVRKNNPKQIRDWNDLAKDGV
                     NIVIANPKTSGNGRYAFLGAYGYGLKATNGNEQEAQKLVASILKNTPVFENGGRAATT
                     TFTQRNIGDVLITFENEANYVSKKLTQGQFEIVYPSYTISAESPVAVVNSIVAKKGTQ
                     KTARAYLEYLWSEPAQELAASLYLRPRNPEVLARHKADFPDLDTFSPEEKFGGWDNIM
                     KTYFADGGIFDRLTAQK"
     gene            complement(11120..11602)
                     /locus_tag="ACFOV4_001384"
     CDS             complement(11120..11602)
                     /locus_tag="ACFOV4_001384"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC7619379.1"
                     /translation="MSLLTLLRPATVQDCKDIFKVHLHSVQYTCILSYNEHALKVWEG
                     LLNTESYLPTISDPDKALWVAEYKGNIQGFFQIDCQEAQLDALYVHPLFHNLGLGTAL
                     LHQAETIAHKSGLSFLKLYASLNSVPFYLLNRYESLGSAVLQLDPSIKIKCELMRKHL
                     "
     gene            complement(11649..12785)
                     /locus_tag="ACFOV4_001385"
     CDS             complement(11649..12785)
                     /locus_tag="ACFOV4_001385"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFC7619380.1"
                     /translation="MKNISLSPPAMLGILGGGQLGRMFTVAAKTMGYKVTVLDPDPDA
                     PAAEFADRHLCAPFNDQAALDELAKCAAVTTEFENVNADAMRFLAKHTNVSPSGDCVA
                     IAQNRIQEKAWIRKAGLQTAPYQVVCKAEDITEASAQFLPGILKTATLGYDGKGQIRV
                     KTLDELKAAFAEHGGVDCVLEKMVDLRSEISVIVCRLNNDNVQTFDPAENIHENGILA
                     YSIVPARLSADVQQQARQMAQRLADELDYVGVLAVEMFVVGDTHELVVNEIAPRPHNS
                     GHHTIDACAADQFQQQVRIMCNLPPADTKLLSSCCMANILGDVWQEDGGEPDWLPLQS
                     HPNAHLHLYGKKTAHKGRKMGHFTVLTTDSDTAFQEAKKLHQSL"
     gene            complement(12782..13327)
                     /locus_tag="ACFOV4_001386"
     CDS             complement(12782..13327)
                     /locus_tag="ACFOV4_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFC7619381.1"
                     /translation="MTYEKLYELRQTLRPTTKDGLYTDNEKSREILTVRWSGNTENPK
                     NFSAVAIGINPSKANDERSDKTLTQLARFLDMYGFTNFKMLNIFSSYSTQQTGIRANT
                     QTDFSKFKGCLEDADMIILAWGTDRGAYKDEKNRILEFLKAEKFMEKVFCISETGNSS
                     DTRHPSRISYSYQLVQFEESA"
     gene            complement(13324..14799)
                     /gene="trpE"
                     /locus_tag="ACFOV4_001387"
     CDS             complement(13324..14799)
                     /gene="trpE"
                     /locus_tag="ACFOV4_001387"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HFC7619382.1"
                     /translation="MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYT
                     YLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHN
                     RFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQEL
                     AVIDNLSGKIHLVVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSE
                     FGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSPLALYRALRTLNPSPYLFYY
                     DFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEH
                     VMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKEGVTNMDILAAT
                     FPAGTLSGAPKVRAMEIIEEVEQEKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTL
                     YVQSGAGIVADSDPTSEWQETQNKARAVIRAAQMVQEGLDK"
     gene            complement(14910..15275)
                     /locus_tag="ACFOV4_001388"
     CDS             complement(14910..15275)
                     /locus_tag="ACFOV4_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619383.1"
                     /translation="MFKRPEEIIVLILAVLWIAGTYFLAALFGADAYTVLKITALTLL
                     WSAASFLLWQKNLSRHIWPLLLGCLTACWWPYLNQSVAPGSLPWYASWTFKTILALIP
                     VTAGYLFKWKQYRQRKTKP"
     gene            complement(15296..17206)
                     /locus_tag="ACFOV4_001389"
     CDS             complement(15296..17206)
                     /locus_tag="ACFOV4_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFC7619384.1"
                     /translation="MNILSVENASFAIGHVALLDKTSFQLDSGEKVGLIGRNGAGKSS
                     FLKILAGVQKLDDGQIIVQNNLKIVYVPQESFFDKDATVFDTVAEGLGKIRDLLRRYH
                     RVGHELENGSGEALLKELNELQLEIEAKDGWKLDAAVKQTLGELGLPENEKIGNLSGG
                     QKKRVALAQAWVQKPDVLLLDEPTNHLDIDAIIWLENLLKAFEGSLVVITHDRRFLDN
                     IATRIVELDRGILRSYPGSFSKYSEKKAQELAVEAEHNRLFDKFHAQEEAWIRKGIEA
                     RRTRNEGRVRRLEELRRQRAERRNVQGQVNFKLDSGEKSGKIIAELEHASFAYGGKVI
                     MDKFSAILQRGDKIGLIGPNGIGKTTFLKLILGELQPTYGRIRIGSKQEVAYFDQFRS
                     ALNENETVFYTLGQGNDYVEVGGKKKHVMSYLEDFLFPPARAQSPVSSLSGGERNRLL
                     LAKLFTRPANILILDEPTNDLDIDTQELLEDLLRDYQGTVFLVSHDRMFLDNVITQSI
                     IFEGNGRLKEYIGGYQDYIDAKSREAKIQTESAPKTADAEPVKEKPKANRTVKLSYKE
                     QRELDALPDEIAALEAEQAEINAQLSDPEIFKDYEKAGALQSRAEEIEMLLLEKLERW
                     ELLETKQNGNAV"
     gene            complement(17225..17869)
                     /locus_tag="ACFOV4_001390"
     CDS             complement(17225..17869)
                     /locus_tag="ACFOV4_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFC7619385.1"
                     /translation="MLASAIDFILHIDQHLLALSAQYGVWIYAILFLIVFCETGLIVT
                     PLLPGDSLLFAAGGIAALGGMDIHLMVALLSLAAILGDALNFTVGKYFGGRLFANPDS
                     KIFRREYLDKTHRFYEKHGGKTIIIARFVPIVRTFAPFVAGMGKMHYAKFIRYNIIGG
                     LLWVILFSYAGYFFANFPVVKNNLGLVMGGIIIVSVLPGAVEIARAKLAVKSKR"
     gene            complement(18032..18850)
                     /gene="opc"
                     /locus_tag="ACFOV4_001391"
                     /gene_synonym="opcA"
     CDS             complement(18032..18850)
                     /gene="opc"
                     /locus_tag="ACFOV4_001391"
                     /gene_synonym="opcA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Opc"
                     /protein_id="HFC7619386.1"
                     /translation="MKKTVFTCAMIALTGTAAAAQELQTANEFTVHTDLSSISSTRAF
                     LKEKHKAAKHIGVRADIPFDANQGIRLEAGFGRSKKNIINLETDENKLGKTKNVKLPT
                     GVPENRIDLYTGYTYTQTLSDSLNFRVGAGLGFESSKDSIKTTKHTLHSSRQSWSAKV
                     HADLLSQLGNGWYINPWSEVKFDLKSRYKLNTGVTSLKKDINQKTNGWGFGLGANIGK
                     KLGESASIEAGPFYKQRTYKESGEFSVPTKSGDVSLTIPKTSIREYGLRVGIKF"
BASE COUNT         4363 a         4274 c         5082 g         5208 t
ORIGIN      
        1 gcgcccgctg ccgcctaaaa ggcagcccgg atgcctgatt atcgggtatc cggggaggat
       61 taagggggta tttgggtaaa attaggaggt atttggggcg aaaacagctg aaaacctgtg
      121 tttgggtttc ggctgtcggg agggaaagga attttgcaaa ggtctcagag tgagtttatt
      181 ttggggcggc ggcaggtcgg gggcaagcgg tgtggggctt ggttgtggtt tttaggtttt
      241 tgggggtaaa aaatgccgtc tgaacttttc agacggcgtt tgttttttct gtccaatcga
      301 ggaactgccg ccatttttcc agcggcatat cggcccgccg cgtttcggta tcgggttcgg
      361 cttcccagcg gcctacctgt atgtagtgct tcaccccgac gatttgcgcc aactcggcct
      421 gtgtcagttt gcagcggttg cgcagggtgc gaaggttgta aggcgtgtag ccgagttcca
      481 tgtcgttgcg gtttattttg tttcgcatat ttttttgact gcccggcggc aggtttcggt
      541 aaggacggcg gcaaatcggg cttcgtctgc cggttttccg tcgaaaaaaa taaaatcgta
      601 aagggtgatg ccgttttcgg aatggcggta atgcccgccc gggcattcgc tgtctgtctg
      661 cctgtggatt ttggcaatca ggcggggata gcggcaatgg gtaatgaaac ggcttgcgcc
      721 gtcttgcccg ataatccatt cggggtagcg gttgaatagt gcggctctgt tcattttgtt
      781 cgggttgttc gggggataaa gcccctcgcg gggcttgtgg tcaggcaaat ttgaatatca
      841 gtgccaacac ggcggcgatg gcggtaacca gcccggtggc cgccatcatg ggataccatc
      901 gggattcttg ggctattttt acggattcgg cgttgatttt gtgcgcgtct gcaatgattt
      961 tggcgatttc ggcatctact tttctcagac tggagtgttt catttcttgt tcgattatgt
     1021 tcatcgtact tcctttcgtt tttggcggtt gccgccgctt gtcggatggt aggatgtctg
     1081 ccatgtgtat atattgatac cttttaggtt ttattgcaag tgttttgggc ggcggcttcg
     1141 tatgcttggc ggtggcggcg gctgtaccat tcggcgagtt cgcgccgctc ttggaggcgg
     1201 tagctgtcgg cggtcaggta gtggtgcagg cttgagaagc cggcgcgttg gagggcggcg
     1261 cggctgatgt ggccgagggc gaggtctgtt gtgagggtgt cttttccggc ggtcaggctg
     1321 atgttggtga agaggtggcg gaatccgtgc attgtgtgtt tggatttgcc gggggtgctg
     1381 ccgtcatagc ccagtcgtcg gatggcgttg tgggcgaatt tgatgctgat gtggtcggga
     1441 tggggggcgg gtttgcgccg tgggcggatg ccggggaaaa ggtggatgtt gtcgccggtc
     1501 tgtgtgtgca gctctcggag tatttctacc gcccagtccg acagtgggac ggtaaagggg
     1561 tgtttggtct tcatgtcggc ggcggggatg tgccataacc gggcggtgag gtcgatgtct
     1621 tgccagcggg cggaaagcag tgcggaggga cgggatgact tccccggttt ccccatcaat
     1681 ccgcgccgcc tcgatttttc cgttggcgcg cagcatttcc accgcctgcc gcaccgacat
     1741 caaccgcttg ccgttgcgcc tcatcgcctc caccaaaacc gccgaaatca atttggcttc
     1801 ttccggttta agctccgtct tgcccgcatc gctgcgccgt ttgcgcgtcg gcttgacgct
     1861 gaccgcctcc agcttgcggt atagcgtggc aaggctgatg cccaattcct gcgcctgctg
     1921 cttaagatat gcagagcgtg cgccgcgttc cattgcttcc gcctgattct cgactgcctt
     1981 aagacgctca atcattgccg gattcatcgc cttctcccgt ttcaccgccc aaccattccg
     2041 gcacattgtc tgtcggtgct tcagtcggca gggcatagct ttcgcgcagt tgctcgcagt
     2101 ccaaaataat ttgattgagc gtgccgacca tctttgcctg atggctgatc ccgtgtgcct
     2161 cactgtgcgc attaagttgg tcgaacaaat ctttcagacg gctcacttga ctgcggatac
     2221 cgacctcaag gcttgttaac tgcatcgcca actcgctgcc tacgtcttcc gccttcggct
     2281 ctctgacaac ggtttgcttc ttagccagct tctcggccag ctcatcaatt ttggctgttt
     2341 tggttttcat cacttcgtct ttggcggcga ggttttcgcg gctttcgcgc agggcgacgc
     2401 gcagctcgcg caccgtcatt cggtccacat cgtcaaaggt catgccgttg acttcttccc
     2461 cttcggccaa acccaccagc gtaacgtctt cttcgaccaa gagttccagc agcttcgact
     2521 tgcccaaatc catcagcttc ggcgcggctt tctgcatttg cggggtcgca aagcggcgag
     2581 tggctgacat cagacgtgat gtttctgcga tacccagccc aaattggctt ttcacaattt
     2641 ccataaaccg tccgtgttcc gtatgctctt ttaaaataat cagcgcacgt cccagttcga
     2701 acatgccttc catcgtctgc cgtactgctt gacgaccgcg ttcaacccaa cgctcttcgc
     2761 tataagtctc gccgttaccc cactgctcca tcaccagcac actgcgcatc gctgcctgat
     2821 tgcttacttt gtcggttgcg ataatttcaa tttctgtatt cattttttat ctccaaagtt
     2881 tccgacgtcg gaaactttca aaatccgtta atccacatcg acccgcttgc cgatttcggc
     2941 aatcttgctt tgcagccgtt catgctgctg cctgaaccgc tctgcgattt gcagggtttt
     3001 gatgccgtag gcgtagttgc cgttttcaag tttgatgacc aatcccgagg caaccaaatc
     3061 atcaatatcc ctgctgactt gcgatggcgt cagccccagt ccgaccgata aatccttatt
     3121 gctcagaccg ataatcggat gctcgtcaag cgcgataaag accctcaata gccgttgtac
     3181 ccttttactt tctgccatcc gcatcctcct tatttcagtc ccagcttctt ggcaatttca
     3241 tgccccttgc cgtaattgcc tttgcgctgt ccgccgacca ccagatacac atcgcgcggc
     3301 ttaaagccgt tctctcttgc ccactgcgcc agcgtttggc cgttttgggc aaaattttct
     3361 tttagttttt caacagtata gccatagata gccctttccc attgtgataa aatagtgaac
     3421 tatttatgca ctagaaatta attagtgcat taccaatgcg tgaattatga gattttaaaa
     3481 tctcttttac aaggattatt ttgtgatttc taaatctctt tttggtaatc gtttgaaaga
     3541 aaaaagaaag tttttagggc ttacccaagc acaagctgct gaaaaagcag gtattgagcg
     3601 cgaaacatgg ggcaaatacg aacgtggcgt atttatgcct agtggagatg tattgctctc
     3661 ttttttgaat atgggaatag atgtgagcag cttatttgct gctgaacagg gaattaggcc
     3721 gtctgaaaat tctgaaatta gtaaggaaga gtcagagtta ttagggtatt accgccaagc
     3781 cagcgataac ggcaaatttg tcattctcag tgtggcaaaa ggcgcagaga aaaaagcagc
     3841 cgaaaatact caagtttcag ccacgcataa aacagcgtga tttttaaatc caaaatggag
     3901 acagtcttat gtttgacttt gaacaacaaa tcaaatgggg tgagcgagcg gaagaaatcg
     3961 ttaaagaggc agccacccag aacaatatcg aaattcccga acctttggct tcggcattag
     4021 ctaaggcggt aaaagtgcat tatctaagcc aagctggtgt gttttctttg gtagaagcct
     4081 atgcagacac ggtaaatcca actgaaaaag aagtagatta ccaagcaatc ggcaaagagc
     4141 tatttgaaaa ataaaaaatg ccgtctgaaa ttttcagacg gcatttagga cactccgaca
     4201 gtcgggctgc tccggtgttc tgaaacggat attaagcaat tgaagcggcc gtgcatttta
     4261 aaacgcatta aaaactaccc cgacatacag gtcatcgggc aggtggttca ggtgttgaaa
     4321 gatttgaatt gatgccgtct gaatttattt tttcgacaca gatattaaaa gagaaaggac
     4381 tgtacaaatg gcaaaaaaaa ctactaaaac tattcattat ttacgtgcgc agcaaaacca
     4441 tagcttgttc gatttagagg tagcattaag aagggttttg tcagctgctc ctactgttca
     4501 agatacacaa attgaacaat acaatcagct tacccaaatc atgcatagaa ctttggatcc
     4561 taaagatgta aaaggcaatt caattggtgg attactgata cacattggca gcggtacaaa
     4621 agatgaacat atccgcacta tgagcaatag acctgtacag caagatgatc atggtggaac
     4681 acaagctcct ccaagtggat attccttttt gcgtaaagag gcttttttgt atattgttgg
     4741 acaccatgta attttttgcg gacatggttt tttgtcagca tcaacggttg cttcttattt
     4801 aagtttactt agcaataaat tgagagagaa caatccggat attgttcaat ttaatattga
     4861 attcaaagca gtaggcaatt gcgacaagtt gtcattgata caacaacatg gggtaaaaag
     4921 tattctttta gatgcttcgg catatcaatt atccagaaac agactgtatc aagatagccg
     4981 ttcaaccatt gctaaagcat tagggaaagt tggtagtgta tttacaagcg aattgagtga
     5041 tgaggaattg gaagcacaat ccgaaattca tatcaattta gaagtcttgc taaacggtaa
     5101 ttcgagagcc agtattgaag cgcaatcgct gatgcaggag caggcagagg aaattattga
     5161 tgatgaaacg gttaatcaag gattttccat taccacgcaa caaggtgaag tgattcagcc
     5221 ctctgatgta aaactgtcta aatctgttag aataggacga tacgatgaag ccaactcgtt
     5281 actccctgac tcggcattta cagcaatcag tgaatatttc ctagaactcc aaagcagaaa
     5341 cttaactgaa caatgaaaaa atatctgccc ttactacgtt ttttgttgat tgcttgtata
     5401 tcagcatttt tagcatggaa agggcaacct tttgttcatg ggaacgagaa ggccgttgat
     5461 ttaattatta acgtatttgc aatcttagcc ggttttttaa ttgccattat gacattgttt
     5521 agtgatatga ggtttgatga agatgcaaat tggcgacaaa ttcaaattcg tgaaggcgta
     5581 caagaacaac ggtatataaa acattcctta cttttttaca catatcttgc cgtattagtt
     5641 tgtgttttta ttgtcatctt gttggctcat aaagaagaat acaaaaatgg accagccatt
     5701 ttttggcttg aacggagcta tttattttta gcctgtattt ccatttttta ttctgtattc
     5761 ttacctggga atttaattaa aagccgaaaa gaagagttta aaaaattaat ggaaaagaag
     5821 aaacccaaaa tctagaacga gttttaaccc cctttaaaat cccattcaga cgaccttttc
     5881 taaaatccct gtattgattt ttaattcaat acagggattt ttccatgtca gacaagttca
     5941 accaattcat caaccgcgtc ctctctcacg agggtggtta cgccaaccat cccaaagacc
     6001 ccggcggcga aaccaattgg ggcatcacta agcgcaccgc acaggcaaac ggctacaacg
     6061 gctccatgcg tgccatgacg cgtgaacagg caatcagcat ttaccgtaaa gcgttttggg
     6121 agcgttaccg cgccgaccaa atgcccgaag cggtcgcttt tcaatttttt gatgcctgcg
     6181 tcaaccacgg ttacggcaat gccgcccgta tgctccaacg cgccgcaggc gtgccggacg
     6241 atggaatcat cggcgaaatc agcctcaaag ccatcaattc ccttcccgaa aacgaccttt
     6301 tattgcggtt caacgccgag cgtctggtct tttataccaa gctgggtacg ttcacctctt
     6361 tcggcaaggg ctgggtacgc cgtgtggcgc aaaacctgat tcacgccgcc gcagacaatg
     6421 ccgattgagg agcaaaccat gtcaaaaaag tccattctcg ccctgatggc cgcagccatg
     6481 cagcccgatt tcagccacag cgacctaggc attcgctacg ccatgccgac tcagggatgt
     6541 tggacgcaag cccaccgcaa gagcggggta gccgccgcga aacgcgcagc caaaaaaaag
     6601 cgtcacaaat aaccgccttt ttccgatggc tgggcggctt ggtctctaat ccggccacag
     6661 ggaaaatcag ccataccaaa ctttgggcaa acgtcgccgc agccgccatg acttggaagt
     6721 tcgtgcaggc ggcggacgcg cccgaatggc tttggtgggc atacggcgcg atggtcggcg
     6781 ggtatgcatt aatcaaacgc ggcatcgccg ccgtaccgca gttggcggaa gtcaaaaaat
     6841 ccgcaaatca ggaagggggg cggcaatgat tgaatttgtc cgagccaaaa aacggctgct
     6901 ttgggcattt gtgcttttgc ttgtgtggac gtgcggttac cgatacgccg ccgacaaggc
     6961 cgaagcggaa caaaccgccc tgattgccac ctatcggcat tcttctatgg ttgcggcgga
     7021 acaatatgcc ttgcagctta aaaaagcgca ggacgaaagg cagcggtggt acgacttttc
     7081 ccaaaaacaa ggaagaaagc ccgtgaaaaa acagtatccg ccgcaaacga aaaaagccgg
     7141 ctatctgaaa accaaggaag aactgcttgc ggaattggct tgccttacag cggaaatggc
     7201 tgccctaaaa aagcccgatg ccttaatcca tgggaaagaa gtgcggcaga aagaacgcaa
     7261 ctcgtcgcag ggttaaggca atgccatccg ttgaactgct gttggagatt gtcggactgc
     7321 cacgcggcac cttctattac caattggccg tccaatcggc agaagacaaa tatgccgatt
     7381 tgaaacggca tatccatgat atttatcgac gacataaggg aagatacggc taccggagga
     7441 ttgcggcagc catccgtcac gcaggaacac cggtcaatca caagaaagtc agccgtctga
     7501 tggcgaagac ggggctgaag gcagtgatac ggcggcgcaa ataccgctcg ttcaaaggag
     7561 aagtcggcaa aattgcgccg aatatcctgc gacgctgttt ccatgcagaa aagccgaatg
     7621 agaaatgggt aacggacgtt accgagttca atgtaggcgg agaaaagata tacctttctc
     7681 cgattatgga tttgtttaac ggggaaatcg tcagttaccg tattcaaatc cgcccgactt
     7741 tcgatttggc cggcgagata ctgaaaggtg cgccggagaa accgggatcg tctgaaaagc
     7801 cgatactgca ttcggatcaa ggttggcaat atcagatgtt tttttatagt ggattaaatt
     7861 taaatcagga caaggcgatg aagccgcaga cagtacaaat agtacggcaa ggcgaggcaa
     7921 cgccgtactg gtttaaattt aatccactat acaacaacga tagaatcaag ttgaaattaa
     7981 aagggctgag ccttgttcag tacagaattc agtccctgaa agccgcttga ttaaactgtc
     8041 cgactttttg gggtcagttc ggcttcggca tttttttatc cgtttggggg taacttgttt
     8101 ggaaagctgc aagcttataa ataaaggatt acatttaagt tttgggtaac ctttttaaaa
     8161 aaatgcgtga tgacttttgc atttttaagg cgttttttgg ggtaattcgt gaaaagttac
     8221 cccaaaagtt accccataaa tggcgaaaac tcaagcatac gccagcatcc tgcaacacaa
     8281 aaaagccttg aaactgttga agttcaaggc ttttttgtgt tgcaggatgc tgctgaaaat
     8341 agggtatggt ggaggcgggg ggaatcgaac ccccgtccga aagtcctcta caaagcgttc
     8401 tacatactta gttgtgtcta tttgaaaatc ttatttccat catgccgacc aacaggcctt
     8461 ttggaaacca gttaccttaa gtcttatttc ctgccaagta acccggtagg aaaccagtca
     8521 atgtaagatg acgttgcggt ggctttcgcc acacagccca ttgaccgact gctgcaacgg
     8581 ctagccttaa gcggctaaag cgtaagtttc gtcgtttgcg actatttgaa ttcagtgttt
     8641 tacgggaatc tgagaccccg gtatgcccgc atctgcttcg caaccctcgt cgaaaccaag
     8701 gtcgccccca gaaatggttt gcaaattata cggatattgt gcggtgctgc caagtctgtc
     8761 ggagaaattt gtcagtcttg ctgccttaat ttgcgtttga gcaggatgcg gacgcagccg
     8821 tcgttgcctt cccggggttc ggcgtaggcg agtacgtcgg ggtgttgcat cagccagttt
     8881 cgggtcatat ttttcagaac gggtttgtag cctttggaac ctaatccgct gccgtggatg
     8941 atttcgccgc atacgccgcg tttttgggtg aatgcgatga attcgttgag gactttttgg
     9001 gcttcttcct gtgtgtagcc gtgcaggtcg acatcggtaa cgacgggata gtatccgttt
     9061 ttcaggcgtt ggatgtcgtt ttttccctgt ccgtttttgc tgaagctggc gggcgggtcg
     9121 ttgtatgtgc tgccgatgta gaagtagttt tcttcgtcgg cgcggttgtc tttgggacgg
     9181 actttgatgg gggttttgtc gggcggcgca taatattgct gccggttttt taatggggag
     9241 acttgtccga ctgcttgtga aaaatcgaaa tcctgttctt gtttttgctt gtttttttcg
     9301 gctgcctgtt tttctgccgc ttctttttgg gcttgtttgc ccagttgttt gaggatgttt
     9361 tggaagtcgg tattcatatt ttttcctgtt atttgtccga tggctgtttc gggcggggtt
     9421 ttaatttgcc ggaatgttta ccaatcgggg gaggatgatt ttgttgcctg cgtatgtttt
     9481 ttgaaagtgt gattgtatat caaaaagaaa tgcggcaacc gtcggcagtg ttgattgccg
     9541 gaaatgcgga ccggtcgaac cgatatgccc gaacgcctga taaagtttta aaaacctgcc
     9601 ttgcgaagca ggctgacgtg ttttgccaat cttgaattgc cggaaacgcg aaacacggaa
     9661 atctgatgtt ttataaatgt tccgatacga actgcaaaat attggttttg tttctgacag
     9721 gcaaaagcac tgtttatttg gctgtcaaaa gggatggtta aggaaagtta tgcgcccctt
     9781 tgatgaagcg cgccccagat aaggatggtt gcgccgacgg cttcagacgg cattttggcg
     9841 gcggtgttgg gttttgtatc cggtttgccg ttgtgtcttg tgatgatgat tttgggcgcg
     9901 gtttttctgt tttgatgtgt ggaatgccgt ctgaaaggcg gttcagacgg catagcggtc
     9961 atttttgtgc ggtcaggcgg tcgaatatgc cgccgtcggc gaagtaggtt ttcatgatgt
    10021 tgtcccatcc gccgaatttt tcttcgggag agaatgtgtc taagtctggg aagtcggctt
    10081 tgtgtcttgc caatacttcg gggttgcggg ggcgcaggta gagtgaggcg gcgagttctt
    10141 gcgccggttc gctccaaagg tattcgagat aggcgcgggc ggttttttgc gtgccttttt
    10201 tcgcgacgat gctgttgacg acggcgacgg ggctttcggc ggaaatggtg tagctcggat
    10261 agacgatttc aaactgtcct tgggtcagtt ttttgctgac gtagttggct tcgttttcaa
    10321 aagtaatgag tacgtcgccg atgttgcgtt gtgtgaaggt ggtggtggcg gcgcgtccgc
    10381 cgttttcaaa aacgggggtg tttttgagga tggatgcgac gagtttttgg gcttcctgtt
    10441 cgttgccgtt ggtggctttc agaccgtaac cgtatgcgcc gaggaaggcg tagcgtccgt
    10501 tgcccgaggt tttgggattg gcgatgacga tgttaacgcc gtctttggca aggtcgttcc
    10561 aatcgcggat ctgtttgggg ttgttttttc ggacaaggaa aaccatagtg ctggtgtagg
    10621 gcgcggcgtg gtcggggagg gcttgttgcc agcctttttc taccagtcct tttttttcga
    10681 gcaggtcgat gtcggaggat tggttcatgg ttacgacatc ggcttgaagg ccgttggcta
    10741 cggataatgc ctgtttgctg gagccgccgt gggactgttg gatgctgacg gatgtgccgg
    10801 ggtgttcgga ttggtatgtt ttgataaata aggggttgta ttctttgtaa aaatcccgtg
    10861 ccacatcgta tgaggcgttg agcagggtaa tgttttttcc gtcggattcg gtattggccg
    10921 gggcattttg tccggacgga tgatttgaat cggctgcggg gctgcaggcg gtgagcaggg
    10981 ctgcggtata gagtgccggt gcgtaggttt tcatatgctt gtcctgtcgg ttggtagatg
    11041 gggcaacttt atacggctgt ctgcgcttgt ggaaataatg tttgatttga agattatcag
    11101 ttttggttat aaggacggat cagaggtgtt tccgcatcag ttcgcatttg attttgatgc
    11161 tggggtcaag ctgcaatact gccgaaccga gcgattcgta gcggttgaga aggtaaaacg
    11221 ggacggagtt gagcgatgcg tagagtttca gaaagctcaa accggatttg tgggcgatgg
    11281 tttccgcctg atgaagtagg gcagtgccca gtccgaggtt gtggaacagg gggtggacgt
    11341 aaagtgcatc gagttgtgct tcttggcagt cgatttggaa aaatccctgt atgttgcctt
    11401 tgtattcggc aacccaaagt gctttgtcgg gatcggaaat ggtcggcagg tagctttctg
    11461 tgtttagcaa gccttcccat acttttaggg cgtgttcgtt gtagctgagg atgcaggtgt
    11521 attggacgga gtgcaggtgg actttgaaga tgtctttgca gtcttgcacg gtggcggggc
    11581 gtaacagtgt cagcaggctc atggcggtat gtcggcggct tcagacggca tctgtgccgt
    11641 tggtcggatt atagggactg atgcagtttt tttgcttctt gaaatgcggt gtccgaatcg
    11701 gtggttaaaa cggtaaagtg tcccattttc cgccctttgt gcgcggtttt tttgccgtaa
    11761 aggtgcaggt gtgcattcgg atggctttgc aagggcagcc aatccggttc gccgccgtct
    11821 tcctgccaaa cgtcgcccaa aatatttgcc atacagcaag aactcagtaa tttggtatcg
    11881 gcaggcggca ggttgcacat aatgcgtacc tgctgctgga actggtctgc tgcgcaggca
    11941 tctatcgtat ggtgtccgga attgtgcggg cgcggggcga tttcgttgac gaccaattca
    12001 tgcgtgtcac cgacaacaaa catttctacc gccaatacgc cgacataatc caattcgtcc
    12061 gccaagcgtt gcgccatctg ccgcgcctgt tgctgcacgt cggcactcag tcgcgcgggg
    12121 acgatggaat aagccaagat gccgttttcg tggatgtttt cggcagggtc gaaagtttgc
    12181 acgttgtcat tgttcaaacg gcatacgatt acggaaattt cactgcgcaa atccaccatt
    12241 ttttccaaaa cgcaatccac gccgccgtgt tcggcaaacg cggctttgag ttcatccaat
    12301 gtttttacgc ggatttgacc tttgccgtcg tagcccaacg tagccgtttt caggatgccg
    12361 ggcaaaaatt gcgcgcttgc ttcagtgatg tcttcagcct tacaaaccac ttgatacggc
    12421 gcggtttgca atcccgcttt gcgtatccat gccttttcct gaatgcggtt ttgtgcaatc
    12481 gccacacaat cgccgctagg ggaaacattg gtatgttttg ccaaaaagcg catcgcatcg
    12541 gcattgacgt tttcaaattc agtggtcacc gccgcgcatt ttgccaattc gtccaaagca
    12601 gcttggtcgt taaacggcgc gcacaaatgg cggtcggcaa attctgctgc cggcgcgtcc
    12661 ggatcggggt cgagaacggt tactttgtag cccatggttt tggcggcaac ggtaaacatt
    12721 ctgcctaatt gtccgccgcc gaggatgcca agcatggcgg gcggagaaag agatatgttt
    12781 ttcatgctga ctcttcaaat tgtacaagtt gatagctata actaattctt gacggatgtc
    12841 ttgtatcgct ggaattacca gtttcagaaa tacagaatac tttttccata aatttttctg
    12901 cttttagaaa ttccagtatt ctgttttttt catccttata agcaccgcgg tctgtacccc
    12961 atgcaagaat aatcatatca gcatcttcca aacatccttt aaatttggaa aaatcggttt
    13021 gggtgtttgc cctaattcct gtttgctgtg tagagtaact ggaaaaaata tttaacattt
    13081 tgaagttggt aaaaccgtac atatccaaga aacgtgcaag ttgggtaagg gttttgtcgc
    13141 ttctttcatc atttgcttta cttggattaa ttcctatagc aacagctgag aaatttttag
    13201 gattttctgt gttgccgctc catctaaccg ttaggatttc tcgacttttt tcattatctg
    13261 tatagagacc gtctttggta gtcggtctga gtgtttggcg aagctcataa agtttttcat
    13321 aagtcattta tccaaccctt cctgcaccat ctgcgcggcg cgtataacgg ctcgggcttt
    13381 gttttgtgtt tcctgccatt cggaggtcgg gtcggagtcg gcgacgatac ctgcgccgct
    13441 ttggacgtat agcgtgttgt ttttcaccac ggcggtgcgg atggcgattg ccaaatccat
    13501 gtcgttgttg aagccccata cgccgaccgc gccgccgtag atgccgcgtt tctcctgttc
    13561 gacttcttcg atgatttcca tggcgcggac tttgggtgcg ccggagagtg tgcctgcggg
    13621 gaaggtagcg gcgaggatgt ccatgttggt aacgccctct ttcagacggc cttcgacgtt
    13681 ggaaacgatg tgcatcacat gggagtattt ttcaatcacc attttatcgg ttactttgac
    13741 ttcgcccgtt ttgctgatgc ggccgacgtc gttgcgccct aaatcgatga gcatgacgtg
    13801 ttcggcgatt tctttggcat cgcttaacaa atcttgttcg ttggcaaggt cttcggcggg
    13861 ggttttgccg cgcaggcgcg tgccggcgat ggggcggacg atgacatcgt cgcgttcgcg
    13921 gcggacaagg atttcgggcg aggagccgac gatgtggaaa tcgccgaaat cgtagtaaaa
    13981 gagataaggc gaagggttga gcgtacgcag ggcgcggtag agggcgagcg ggctgtcggt
    14041 aaattccatg ctcatgcgct ggctggggac aacctgcata cagtcgcctg caaagatgta
    14101 gtctttgatt ttgttaacgc aggctttgaa cggctcttcg ccgaattcgc tgacggcttc
    14161 ggtgtgtttg ctgccgagcg aaagcgggat ggcgcaactt tggcgtaact gtgtacggat
    14221 gtcttcgagg cgttcgcggg cgcgttcgta gccgtcgggc tgcgacggat cggcgtaaac
    14281 gacgagatgg attttgccgc tcaaattgtc gatcaccgcc aattcttgcg acagcatcag
    14341 caagatgtcg ggcgtgccga gcgggtcggc tttggtggtg tttttcaggc ggtgggcgaa
    14401 gtgttcaaaa ttgtagatgg tttcgtaacc gaagtagccg accagtccgc cggtaaagcg
    14461 cggcaggctt gggatttcgg gtgttttgaa gcggttgtgg aaggcttcga taaagggcag
    14521 ggggttgccg tcgtgttgct cgacaatttc gccgttttga taaacatcga cgtgtttgcc
    14581 gctggctttg agatagtggc tgcaaggcag gccgataaaa gaatagcggc cgaaacgttc
    14641 gccaccgaca acggattcga gcaggtaggt ataggggcgg ttggcgagtt tgagatagag
    14701 ggaaagcggc gtatccaaat cggcaaggag ttcttgcacg agcgggatgc ggttgtagcc
    14761 ttgggcggct tgggcttggt attcttgttt gctgatcatt tctgctttcc caaagggcgg
    14821 tttcggacgg cgcggcaacg ggcgcgagta tagcatttta tcggaattgt tgacagtctg
    14881 accggagatg ccgtctgaaa aggacgggct tacggctttg ttttgcgctg ccggtattgt
    14941 ttccatttaa acagataacc tgcggttacg ggaatcaggg ctaagatggt tttgaacgtc
    15001 catgatgcat accaaggtaa agaaccgggt gcgaccgatt gattcagata cggccaccaa
    15061 caggcagtca ggcagccgag cagcagcggc cagatatgcc ggctgaggtt tttttgccaa
    15121 aggaggaatg atgcggcaga ccaaagcagg gtaagggcag tgatttttaa cacggtataa
    15181 gcatccgctc caaacagggc ggcgagaaaa tacgtaccgg caatccagag gacggcaagt
    15241 atcaggacaa tgatttcttc aggtcgtttg aacatttttt tcttcctgtt tgatttcaga
    15301 cggcattgcc gttctgtttg gtttccagca gctcccagcg ttccagcttt tccaaaagca
    15361 gcatttcgat ttcttcggcg cggctttgca gtgcgccggc tttttcgtaa tctttgaaga
    15421 tttcgggatc ggaaagctgc gcgttgattt ctgcctgttc ggcttccaag gcggcgattt
    15481 cgtcgggcag ggcgtcgagt tcgcgctgtt ctttgtagga cagtttgacc gtgcggttgg
    15541 ctttgggttt ttctttcacc ggttcggcat cggctgtttt gggtgcggat tccgtctgaa
    15601 tcttcgcttc gcgtgatttt gcgtcgatgt agtcctgata gccgccgata tattctttta
    15661 accttccatt tccttcaaaa ataatgcttt gggtaatcac gttatcgagg aacatacggt
    15721 cgtgtgagac aaggaatacc gtgccttgat aatcgcgcag caaatcttca agcagctctt
    15781 gggtatcgat atccaagtcg ttggtcggtt cgtccaaaat caaaatatta gcaggacggg
    15841 taaagagttt tgccagcaaa aggcggttgc gttcgccgcc agagagtgaa gaaacaggac
    15901 tttgcgcgcg ggcagggggg aacaggaaat cttctaaata gctcatcaca tgctttttct
    15961 taccgccgac ttcaacgtaa tcattgccct gtccgagcgt gtaaaacacg gtttcgtttt
    16021 cattcaacgc gctgcggaac tggtcgaaat aggcgacttc ctgcttgctg ccgatacgga
    16081 ttctgccgta ggtcggctgc aattcgccca aaatcagctt gaggaaggtg gttttgccga
    16141 taccgtttgg gccgattaag ccgattttgt cgccacgctg caagatggcg gagaatttgt
    16201 ccataatgac tttgccgcca taggcaaacg aagcgtgttc caattcggcg atgattttgc
    16261 cgcttttctc accgctatcg agcttaaagt tgacctgtcc ctgcacgttg cggcgttctg
    16321 cacgttggcg gcgcagctct tccaaacggc gcacgcgtcc ttcgttacgg gtacgtcgcg
    16381 cttcgatgcc tttgcgtatc cacgcttctt cctgagcatg aaatttgtca aacaagcggt
    16441 tatgttccgc ctcgactgcc aactcttgcg cttttttctc actgtattta gagaacgagc
    16501 cgggatagga acgtagaatg ccgcggtcaa gttcgacaat ccgcgtagcg atattatcca
    16561 aaaaacggcg gtcgtgggta atcacgacca agctgccttc aaacgccttg agcaggtttt
    16621 ccaaccagat aatcgcgtca atatccaaat ggttggtcgg ttcgtccagc agcaatacgt
    16681 cgggcttctg cacccaagcc tgcgccaagg cgacacgctt tttctgaccg ccggaaaggt
    16741 tgccgatttt ttcgttttcc ggcaaaccga gttcgcccaa agtctgcttg actgccgcat
    16801 ccagcttcca gccgtccttc gcttcgattt caagttgtaa ttcgttgagt tctttcaaca
    16861 aagcctcacc cgaaccgttt tccaactcat gaccgacgcg gtggtaacgg cgcaataaat
    16921 cgcgaatttt acccaaacct tcggcaacgg tatcaaatac ggttgcgtcc ttatcaaaaa
    16981 aggattcctg cggtacataa acgattttga ggttgttttg aacaataatc tgcccgtcgt
    17041 cgagcttttg cacgccggcg aggattttta aaaacgaaga cttgcctgcg ccgttgcgtc
    17101 cgatcaagcc gactttttcg ccgctgtcga gttgaaaaga agttttgtcg agcaaggcaa
    17161 cgtggccgat ggcaaaagaa gcgttttcta cagataatat attcatgata caaattctca
    17221 acagttaccg tttggatttt accgcaagtt tggcgcgggc aatttcaacc gcacccggca
    17281 ggacggaaac aataatgatg ccgcccatca ccaagcccag attgtttttt acgacgggga
    17341 agttggcaaa gaaatagccc gcgtaagaaa acaggataac ccacaacaag ccaccgatga
    17401 tgttgtagcg gataaatttg gcatagtgca ttttccccat accggcgaca aagggggcga
    17461 aggtgcggac gatgggcacg aagcgcgcga tgataatcgt tttgccgccg tgtttttcgt
    17521 aaaaacggtg ggttttatcg agatattcgc gtcggaagat tttagaatcg ggattggcga
    17581 acagcctgcc gccgaaatat ttgccgacgg taaaattgag cgcgtcgccg agtatggcgg
    17641 caaggcttaa taatgcaacc atcaaatgaa tatccatacc gcccagcgcg gcaataccgc
    17701 cggccgcaaa cagcagcgaa tcgccgggca gtaagggcgt aacaatcagg ccggtttcgc
    17761 aaaaaacaat caaaaacaga atcgcataaa tccacacacc gtattgcgcc gacagcgcga
    17821 gcaggtgttg gtcgatatgg aggatgaagt cgatggcgga ggcaagcacg gcgcgttcct
    17881 aaaaaaacaa accgcgtatt ttaaccgatt ggaaaaatgc cgtctgaaat tttcagacgg
    17941 catcggctat tcaaattcat ttcacgtaaa aaccgcaaac caaaatagtt tgcggtttgg
    18001 catttaaagc gacaatgatg atttcaaatc atcagaattt tatgccgacg cgcaagccgt
    18061 attcacgaat actggttttc gggatggtga gcgatacgtc gccactcttg gttggtacac
    18121 taaactcgcc ggattctttg taagtacgtt gtttgtagaa cggccccgcc tcgatgctgg
    18181 cggattcgcc cagtttttta ccaatatttg cacccaatcc aaagccccag ccgttggttt
    18241 tttgattgat gtcttttttg agactggtaa cgccggtgtt taatttatag cgggacttga
    18301 ggtcaaattt cacttcagac caagggttga tataccagcc gttacccagt tgggaaagca
    18361 aatccgcgtg aactttggct gaccacgact gacggctgct gtgaagcgta tgcttggtgg
    18421 ttttaatgct gtcttttgaa gattcaaaac ccaagccggc acccacacgg aaatttaaag
    18481 aatcacttaa cgtttgggtg taggtgtagc ctgtgtaaag atcgatacgg ttttcaggaa
    18541 cgccggtggg cagttttaca tttttagtct tacccagctt gttctcatct gtttccaaat
    18601 taataatatt ttttttgctg cgcccgaaac cggcttccaa gcggatgcct tggttggcat
    18661 caaaaggaat atcagcacgt acgccgatgt gtttggcagc tttgtgtttt tctttcagga
    18721 aagcacgagt tgaagaaatg gaagagaggt cggtgtggac ggtaaactca ttagcggttt
    18781 gaagctcttg tgcagcggcg gcagtaccgg tcagggcaat catggcacat gtaaaaactg
    18841 tttttttcat agttaaaatc tccaaaattt ggattgtagt cggatatggt aacataacgt
    18901 aaataatcgt tacgcttaca attatat
//
LOCUS       DAXISH010000041        18836 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.041, whole genome shotgun sequence.
ACCESSION   DAXISH010000041 DAXISH010000000
VERSION     DAXISH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 18836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18836
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.041"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(12..521)
                     /locus_tag="ACFOV4_001392"
     CDS             complement(12..521)
                     /locus_tag="ACFOV4_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003662333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HFC7619387.1"
                     /translation="MTMILSILSLFFIIRLLFLAVSIKHEKALIAKGAKQYGKTNSTL
                     LAAVHTLYYLACFVWVWLSDTAFNGISLIGTLTVMASFVILSLIIKQLGEIWTVKIYI
                     LPNHQINRSWLFKTFRHPNYFLNIIPELIGIALLCQAWYVLLIGLPIYLLVLFKRIRQ
                     EEQAMATLF"
     gene            complement(853..1185)
                     /locus_tag="ACFOV4_001393"
     CDS             complement(853..1185)
                     /locus_tag="ACFOV4_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619388.1"
                     /translation="MQILSFQPDIAERMLEGTEGESVNENAQFVRTDNGYWIAWHEGV
                     AALLAPDTPPGIPCFWVEGTESLEELCVMVERGEFDEVEEFDGDDDEWLETAQGCGHH
                     GEACACGH"
     gene            1475..2311
                     /gene="cysT"
                     /locus_tag="ACFOV4_001394"
     CDS             1475..2311
                     /gene="cysT"
                     /locus_tag="ACFOV4_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit CysT"
                     /protein_id="HFC7619389.1"
                     /translation="MLPLKTPGVLPGFKLSLGLTVLCLSLLVVLPFAMMAAKAAEIGW
                     GGFWNTIAEPNVLAAVWLSLRMSFYAMLTNVVFGTLVAWVLVRYEFPGKGLANALVDL
                     PFALPTAVTGIALATLYAPNGWIGRFFEPLGIKIAFTPVGIWIALVVVSLPFIVRAVQ
                     PVLEELSGEYEEAAATLGANRFTTFRRVLLPEITPALLTGAGMMFARATGEYGSVIFI
                     AGNIPMVSEILPLIITGKLEQFDVQGASAVALFMLLVSFVILFALNVMQWALGRRSGA
                     KG"
     gene            2563..3423
                     /gene="cysW"
                     /locus_tag="ACFOV4_001395"
     CDS             2563..3423
                     /gene="cysW"
                     /locus_tag="ACFOV4_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit CysW"
                     /protein_id="HFC7619390.1"
                     /translation="MKPYSANPNLTEPRRLRVLLIAAALGFLLLMLVVPLVAVFYEAL
                     KGGWDLYLKSLNDPEAWSAIKLTLITALIVVPVNAVLGVAMAWLLTRFDFRGKQLLTT
                     LLDLPFSVSPVVAGLMFVLLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVA
                     REIIPLMQAQGDSEEQAALILGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGA
                     VSVVSGHIRGETNTVPLLVEIFYNEYNFTGAFALSGVLALLALATLAVQNIITKLQDK
                     KLAAAERNAV"
     gene            3420..4493
                     /locus_tag="ACFOV4_001396"
     CDS             3420..4493
                     /locus_tag="ACFOV4_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HFC7619391.1"
                     /translation="MSITIQNLNKHFGNFHALKNINLNVPTGKLVSLLGPSGCGKTTL
                     LRIIAGLENADGGKILFDGQDVTAKHVRERKVGFVFQHYALFRHMNVFDNVAFGLTVL
                     PKSERPSKEQICTKVEELLKLVQLSHLAKSYPHQLSGGQRQRIALARALAVEPKLLLL
                     DEPFGALDAKVRKELRTWLRDIHHNLGVTSILVTHDQEEALEVSDEIVVMNHGKIEQT
                     GSAEAIYRKPENAFVTEFLGETDAFEGRIEKGFWHYNGFAWKLDAQYKWQEQTATGYI
                     RPHEWQIAAEHETPMICAEIEKVHAVGALTHILVKHGKQDVHITLAGSDAARYPIAEG
                     KELKLIPKQVYVFSQNELIEYSI"
     gene            complement(4550..6076)
                     /gene="ilvA"
                     /locus_tag="ACFOV4_001397"
     CDS             complement(4550..6076)
                     /gene="ilvA"
                     /locus_tag="ACFOV4_001397"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HFC7619392.1"
                     /translation="MNTPLPYSNYLIRILTASVYDVAVETPLEPARSLSVRLKNNILL
                     KREDLQPVFSFKIRGAYNKMSKLPKDALACGVIAASAGNHAQGVALSAQRLGCRAVIV
                     MPETTPKIKVDAVKSRGGEVVLRGVSYNDAYDYAMELAEKEGLTYIAPFDDPDVIAGQ
                     GTVGMEIVSQHPDPIRAVFVPIGGGGLAAGVAAFIKQVRPEIKVIGVQTNDSCCMKQS
                     VEAGEIVHLKDVGLFSDGTAVKVVGNETFRLCKELLDEIITVDTDAVCGAVKDIFDDT
                     RSITEPAGALALAGLKAYIAREGAENQTLIAVTSGANMNFHRLRHVSERSELGEGNEG
                     IFAVTIPEERGSFLKFVNILGNRNITEFNYRYGDDEKAHIFVGLQAAGPQDLAVIGSR
                     LDEAGLPNVDLTDDEIAKIHIRYMVGGRTDKVENERLVSFEFPERPGALARFLNHMQG
                     GWNITLFHYRNHGADYGRILVGIDVPPHDAAAFDGFLESLGYSYHEETQNAAYKLFLA
                     "
     gene            6224..7393
                     /locus_tag="ACFOV4_001398"
     CDS             6224..7393
                     /locus_tag="ACFOV4_001398"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFC7619393.1"
                     /translation="MTAHKILPVLLSIILGVSHATAASPAPNKPAVHAAPTFQTPETL
                     TAAHIVIDLQSRQTLSAKNINTPVEPAALTQLMTAYLVFKNMKSGNIQSEENLKIPES
                     AWASEGSRMFVRPGDTVSTDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEA
                     RRLGMKNTVFKNPTGLSREGQVSTAKDLAQLSEALMRDFPEYYPLFSIKSFKFKNIEQ
                     NNRNILLYRDNNVNGLKAGHTESGGYNLAVSYSGNGRHILVITLGSESAETRASDNSK
                     LLNRALQAFDTPKIYPKGKTVAQIQISGGSKKTVRAGFLKEAYITLPHKEAKMAEQIL
                     ETIQPIPAPVKKGQILGKIKIRQNGYTIAEKEIVALENVKKRSRWQRLWACLTGQ"
     gene            complement(7518..8090)
                     /locus_tag="ACFOV4_001399"
     CDS             complement(7518..8090)
                     /locus_tag="ACFOV4_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003755233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFC7619394.1"
                     /translation="MTYEIQASVREAQGTGASRRLRREGQIPGILYGEGQEPVAIAVD
                     HKTVFYALEKESFHTALIKLSLNGETKDVIVRDFQMHPFRREVQHIDFQAVKADQPVR
                     IRVPLHIVNAENSQAVKLQGGRVSLLNTSVEVVALPANIPAFLDLDCAEVVAGDILHL
                     SDIKLPEGVESVSLKRNENLAVATVTGKKR"
     gene            complement(8157..9140)
                     /locus_tag="ACFOV4_001400"
     CDS             complement(8157..9140)
                     /locus_tag="ACFOV4_001400"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0006015 - 5-phosphoribose 1-diphosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009165 - nucleotide biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HFC7619395.1"
                     /translation="MAAYDSLMVFTGNANPELAQRVVRHLDISLGNASVSKFSDGEVA
                     VELLENVRGRDVFILQPTCAPTNDNLMEILTMADALKRASAGRITTAIPYFGYARQDR
                     RPRSVRVPISAKLVANMLYSAGIDRVLTVDLHADQIQGFFDIPVDNIYATPILLNDIK
                     QQRIENLTVVSPDIGGVVRARAVAKSLNADLAIIDKRRPKANVAEVMNIIGDIQGRTC
                     LIVDDMIDTANTLCKAAVALKERGAERVLAYASHAVFSGEAVSRIASSEIDQVVVTDT
                     IPLSEAAKNCDRIRQVTIAGLLAETVRRISNEESVSYLFNEEVMTGSMLLP"
     gene            complement(9307..9382)
                     /locus_tag="ACFOV4_001401"
     tRNA            complement(9307..9382)
                     /locus_tag="ACFOV4_001401"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9347..9349),aa:Gln,seq:ttg)
     gene            complement(9391..9466)
                     /locus_tag="ACFOV4_001402"
     tRNA            complement(9391..9466)
                     /locus_tag="ACFOV4_001402"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9431..9433),aa:Gln,seq:ttg)
     gene            complement(9479..9554)
                     /locus_tag="ACFOV4_001403"
     tRNA            complement(9479..9554)
                     /locus_tag="ACFOV4_001403"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9519..9521),aa:Gln,seq:ttg)
     gene            complement(9562..10407)
                     /gene="ispE"
                     /locus_tag="ACFOV4_001404"
     CDS             complement(9562..10407)
                     /gene="ispE"
                     /locus_tag="ACFOV4_001404"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFC7619396.1"
                     /translation="MNIADGRQAFSAPAKLNLDLRITGRREDGYHNIESIFCLIDLQD
                     TVYLKPRDDGKIILHNPVDGMPQEVDLSYRAASLLQKYARNPAGVEIWLDKKIPTGAG
                     LGGGSSDAATVLLVLNRWWQCGLTQRQLIDSGAALGADVPFFIFGKNAFARGIGDRLD
                     EMDIPKQWYVIVKPPVHVSTAKIFTHESLTRNSASSIMPTFQNLQPFRNDMQAVVFKE
                     YPEVWKAYSELSRYGFALMTGSGACVFTACQDRNSAYNIYRQVSDLYEAYLAEGLSKH
                     PLLSV"
     gene            complement(10417..10998)
                     /locus_tag="ACFOV4_001405"
     CDS             complement(10417..10998)
                     /locus_tag="ACFOV4_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein LolB"
                     /protein_id="HFC7619397.1"
                     /translation="MKHTVSASVILLLTACAQLPQNNENLWQPSEHISSFAAEGRLAV
                     KAEGKGSYANFDWTYQPPVETININTPLGSTLGQLCQDRDGALAVDGKGNVYQAESAE
                     ELSRQLVGFKLPIQYLHIWADGRRVAGAPYRILPDGILEQYGWTVGRTADSGGQVRTL
                     QLNNGNLNIRLVFTEIGMPSETETPERCAARTR"
     gene            complement(11138..12982)
                     /locus_tag="ACFOV4_001406"
     CDS             complement(11138..12982)
                     /locus_tag="ACFOV4_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFC7619398.1"
                     /translation="MLPNRFKMLTVLTATLIAGQVSAAGGGAGDMKQPKEVGKVFRKQ
                     QRYSEEEIKNERARLAAVGERVNQIFTLLGGETALQKGQAGTALATYMLMLERTKSPE
                     VAERALEMAVSLNAFEQAEMIYQKWRQIEPIPGKAQKRAGWLRNVLRERGNQHLDGLE
                     EVLAQADEGQNRRVFLLLAQAAVQQDGLAQKASKAVRRAALKYEHLPEAAVADVVFSV
                     QGRKKEKAIGALQRLAKLDTEILPPTLMTLRLTARKYPEILDGFFEQTDTQNLSAVWQ
                     EMEIMNLVSLHRLDDAYARLNVLLERNPNADLYIQAAILAANRKEGASVIDGYAEKAY
                     GRGTGEQRGRAAMTAAMIYADRRDYTKVRQWLKKVSAPEYLFDKGVLAAAAAVELDGG
                     RAALRQIGRVRKLPEQQGRYFTADNLSKIQMLALSKLPDKREALRGLDKIIEKPPAGS
                     NTELQAEALVQRSVVYDRLGKRKKMISDLERAFRLAPDNAQIMNNLGYSLLTDSKRLD
                     EGFALLQTAYQINPDDTAVNDSIGWAYYLKGDAESALPYLRYSFENDPEPEVAAHLGE
                     VLWALGERDQAVDVWTQAAHLTGDKKIWRETLKRHGIALPQPSRKPRK"
     gene            complement(13147..13983)
                     /gene="panC"
                     /locus_tag="ACFOV4_001407"
     CDS             complement(13147..13983)
                     /gene="panC"
                     /locus_tag="ACFOV4_001407"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HFC7619399.1"
                     /translation="MQIIHTIRELRAWRKNAGKVAFVPTMGNLHEGHLALVREAKKRA
                     DSVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAVVFAPDEKELYPNVEQRY
                     NVEPPNLQNELCGKFRPGHFRGVATVVSKLFNIVAPDVACFGKKDYQQLAVIKGLTED
                     LNFDVEIVPVDTGRAEDGLALSSRNQYLSAAERDEAPRLYCELKAVAESLAQGSLDYA
                     GLERQAADHLTAAGWVVDYVEIRRADTLEVARAGDKKLVVLAAARLGTTRLIDNLEIK
                     LP"
     gene            complement(13940..14116)
                     /locus_tag="ACFOV4_001408"
     CDS             complement(13940..14116)
                     /locus_tag="ACFOV4_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619400.1"
                     /translation="MQTEQGLLLMPSESRFRRHFVLPCAARIIGAFCRAGSPKDKDYR
                     YANHTYHSRTARVA"
     gene            complement(14106..14897)
                     /gene="panB"
                     /locus_tag="ACFOV4_001409"
     CDS             complement(14106..14897)
                     /gene="panB"
                     /locus_tag="ACFOV4_001409"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HFC7619401.1"
                     /translation="MITVNTLQKMKAAGEKIAMLTAYESSFAALMDDAGVEMLLVGDS
                     LGMAVQGRKSTLPVSLRDMCYHTECVARGAKNAMIVSDLPFGAYQQSKEQAFAAAAEL
                     MAAGAHMVKLEGGVWMAETTEFLQMRGIPVCAHIGLTPQSVFAFGGYKVQGRGGKAQA
                     LLNDAKAHDDAGAAVVLMECVPAELAKKVTETVACPTIGIGAGVDCDGQVLVMHDMLG
                     IFPGKTAKFVKNFMHGQSSIQAAVRAYVAEVKAKTFPAAEHIFAD"
     gene            complement(15039..15114)
                     /locus_tag="ACFOV4_001410"
     tRNA            complement(15039..15114)
                     /locus_tag="ACFOV4_001410"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15079..15081),aa:Thr,seq:tgt)
     gene            15280..16071
                     /locus_tag="ACFOV4_001411"
     CDS             15280..16071
                     /locus_tag="ACFOV4_001411"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HFC7619402.1"
                     /translation="MARHPYRRLRPAKSGFPEVGISEEGNIRSLHLGSDTIQSSMNLD
                     HPSELVLSYSRAMMGWLLFTDALPQHITQIGLGGGSFARWIDTYLPDTRQTAVDINPQ
                     VIAIARSLFELPFEGEKFEIIEADGAEYIKVFRHNTDVILVDGFDGEQIIDALVEEPF
                     FRDCRNALSSDGIFVTNWWSGDKRYQRFIERLLSVFEGRVLELPAESHGNVAVMAFQS
                     SPKEQNIDKLKKRADKLSNAYGLDFHRMLAGLKASNPNNGKHFHL"
     gene            16126..16767
                     /locus_tag="ACFOV4_001412"
     CDS             16126..16767
                     /locus_tag="ACFOV4_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFC7619403.1"
                     /translation="MLKPETIHISGPAGILETIHIPSEQVPARGVAVINHPNPLQGGT
                     NTNKVIQTAAKALSKLGFHCYLPNLRGVGGSEGTHDYGRGETQDCLAVIDYARAQHPE
                     APEFALSGFSFGGYVATFAAQARIPDLLLLIGAAVCHYTGRPEPSAVPNVAKTLMIHG
                     AEDEVVEIGKALKWAEPQDLPVITIAGSTHFFHGKLIVLRDTILRFAPVCLNG"
     gene            complement(16845..17768)
                     /locus_tag="ACFOV4_001413"
     CDS             complement(16845..17768)
                     /locus_tag="ACFOV4_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFC7619404.1"
                     /translation="MKKRNNPLPLLNGVKPSYLVLPHEKQFYGLPLLHFLCIRFPFVG
                     ADDWRRRLNSGFVVGSDGAALDEHSLFEPGKVMFYYRETSRESEPRIPFEEKILHIDE
                     HLIVVDKPHFLPVIPSGRFLRETLLTRLRLRPELQHLNVEDITPLHRLDKDTAGVMLL
                     SHNPATRGAYQTMFQNKTVWKTYEALAPTRTDLPYPLDVVSRLVRGEKFFTTQEAEGE
                     PNAHTTVELIENRGEFSLYRLTPHTGKKHQLRVHMMGLGMPLLNDALYPVPSEAGSED
                     YRKPLKLLAKKIAFADPLSGRERVFCSGFCL"
     gene            17932..18792
                     /locus_tag="ACFOV4_001414"
     CDS             17932..18792
                     /locus_tag="ACFOV4_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="meta-pathway of phenol degradation family
                     protein"
                     /protein_id="HFC7619405.1"
                     /translation="MKRIFLPAILPLSAYADLPLTIEDIMTDKGKWKLETSLTYLNSE
                     NNRAELAAPVYIQTGATSFIPIPTEIQENGSNTDMLVGTLGLRYGLTGNTDIYGSGSY
                     LWHEERKLDGNSKTRNKRMSDVSLGISHTFLKDDKNPALISFLESTVYEKSRNKASSG
                     KSWLIGATTYKAIDPIVLSLTAAYRINGSKTLSDGIRYKSGNYLLINPNISFAANDRI
                     SLTGGIQWLGTQPDRIDGKKETARNTSTYAHFGTGFGFTKTTALNASARFNVSGQSSS
                     ELKFGVQHTF"
BASE COUNT         4644 a         5387 c         4377 g         4428 t
ORIGIN      
        1 gatgaaacgg gttaaaaaag tgttgccatc gcctgttctt cttgtcggat acgcttaaat
       61 aagaccagca aataaatcgg caggccaatc aataaaacat accacgcttg acataataag
      121 gcgatgccaa tcagttcggg tatgatgttt aaaaaataat tggggtggcg gaatgtttta
      181 aacaaccacg aacgattaat ttgatgattt ggtaaaatat agattttaac cgtccaaatc
      241 tcccccaact gcttaataat caatgacaat atcacaaacg aagccatcac cgtcagcgta
      301 ccaatcaagg atatgccatt aaaagcagtg tcagaaagcc atacccaaac aaaacacgcc
      361 aaataataaa gcgtatgaac tgccgcaagc agcgtggaat tggtttttcc gtattgtttc
      421 gcccctttgg caatcaaggc tttttcatgt ttaatagaga cggctaaaaa taacagtctg
      481 atgataaaaa acaggcttaa aatgcttaaa atcattgtca ttgatgtttt tccattgaaa
      541 ttgaaataaa tataaatcgg attaatggta tttttaatta atgatgtttc agaccatcat
      601 gctctataaa caattcccat taagtccgcg ccgcaacctg ctataataag tctgcaatcg
      661 gcgcaaatca atgctttgcg tttattgcca tcccaaaata attgatgatg ccttaattat
      721 aataccaaga taagtttttt tattcaataa aatacaaagg gaagcgttcc gcccattgca
      781 aacagatgca atccaccgat tatttaaaaa acggcaaagc cttgcacccc ttgcggcaag
      841 cctgcaatgc ctttaatgtc cgcaggcgca agcttcgccg tggtgcccgc aaccctgtgc
      901 cgtttcgagc cattcgtcgt catcgccgtc aaactcttcc acttcgtcaa actcgccgcg
      961 ttccaccatg acgcacaact cttcaaggct ttccgtgcct tccacccaaa aacagggaat
     1021 gcccggcggc gtatcgggcg caagcagtgc cgctacgcct tcatgccacg caatccaata
     1081 gccgttgtcc gtacggacga attgtgcgtt ttcgttgacc gactcgcctt ccgtaccttc
     1141 cagcatacgt tccgcaatgt ccggttgaaa agataaaatc tgcataagtg ttcctttata
     1201 tgatggtttt ccgtcaaaac aaggtgttat agtggattaa atttaaacca gtacggcgtt
     1261 gcctcgcctt gccgtactat ttgtactgtc tgcggcttcg tcgccttgtc ctgatttttg
     1321 ttaatccact atattttaaa acatcgcgcc cgcttgagaa actgccaacc gctttataac
     1381 aaattcgtct ttgcaccaaa ctttccattc tttccgtttt tcggacggca tcgttaaagt
     1441 agtccttcct tttccttatt ttcagcattg ttttatgtta ccgctcaaaa cgcccggcgt
     1501 actgcccggc ttcaaactca gccttggtct gaccgtattg tgcctgtcgc tgcttgtggt
     1561 cttgccgttt gcgatgatgg cggcgaaggc tgcggaaatc ggctggggcg gcttttggaa
     1621 cacgattgcc gaacccaatg tcttggcggc cgtctggctg agtttgcgga tgtcgtttta
     1681 tgcgatgctg accaatgtcg tgttcggcac gctggtggcg tgggtattgg tgcgttatga
     1741 attcccgggc aagggtctgg cgaacgcgct ggtcgatttg ccgtttgcgc tgccgacggc
     1801 ggttacgggt atcgcgttgg cgaccctgta tgcgcccaac ggttggatag gccgtttttt
     1861 cgagcctttg ggcatcaaaa tcgcgtttac gcccgtcggc atttggattg cgctggtcgt
     1921 cgtcagcctg ccctttatcg tccgcgccgt gcagccggtg ttggaggaat tatcgggcga
     1981 atatgaggaa gcggcggcga ctttgggcgc aaaccgcttt acgacgttcc gccgcgtgct
     2041 gctgccggaa atcacgccgg cactcttgac tggcgcggga atgatgttcg cgcgggcaac
     2101 gggggaatac ggctcggtga tttttatcgc gggcaatatt ccgatggttt ctgaaatcct
     2161 gccgctgatt attacgggca agctggaaca gttcgacgta cagggcgcgt cggcggtggc
     2221 gttgtttatg ctgctggttt cgtttgtgat tctgtttgcg ctgaacgtga tgcagtgggc
     2281 gttgggcagg cgttcgggcg cgaagggttg aggtcgtctg aaatacctgt taccgtcatt
     2341 cccgcgcagg cgggaatcca ttggtgaatt tcggctgcct tatttatttt ctgttttcct
     2401 gttgccctgt ggtggattcc cgcctgcgcg ggaatgacgg tagctagacg tttttattcc
     2461 cttaatcaat aaaaggttgt ctgaaaacga atccgctccc aaaaacacag tttttcagac
     2521 gacctccaaa cattttaaaa ccaaccagag aacaccaccg ccatgaaacc ctattccgcc
     2581 aatcccaacc tgaccgaacc gcgtcggctg cgcgtgttgc tgattgccgc cgcgctgggc
     2641 tttctgctgc tgatgctggt cgtgccgctc gtcgccgtat tttacgaagc cttaaaaggc
     2701 ggttgggatt tgtacctgaa atccttaaac gatcccgaag cgtggtctgc catcaaattg
     2761 acgctgatta ccgcgctgat tgtcgtcccc gtcaatgccg tcttgggcgt ggcgatggcg
     2821 tggctgctga cccgttttga ttttcgcggc aagcagttgc tgactaccct gctcgatttg
     2881 ccgttttccg tatcgcccgt ggtggccggt ttaatgttcg tcttattgtt cggcgcgcac
     2941 acggcattgg gtggctggct cgaagcgcaa ggcatacaga ttatcttcgc catccccggc
     3001 attattctgg cgacgctgtt cgttaccttc ccctttgtcg cgcgcgaaat catcccgctg
     3061 atgcaggctc agggcgacag cgaagaacag gcggcattga tactcggcgc aagcggctgg
     3121 cagatgtttt ggcgcgttac cctgcccaac atcaaatggg cgttactcta cggcatcatc
     3181 ctcaccaacg cccgcgcgat gggcgagttc ggcgcggtca gcgtggtatc gggacacata
     3241 cgcggcgaaa ccaacaccgt cccgcttttg gtcgaaatct tctacaacga atacaacttc
     3301 accggcgcat tcgccctctc cggcgtattg gcacttttgg cactggcgac gctggcggtg
     3361 cagaacatca tcaccaaatt acaagacaaa aaactcgccg ccgccgaaag gaacgcagta
     3421 tgagtatcac catccaaaac ttaaacaaac acttcggcaa ttttcacgcg ctgaaaaaca
     3481 tcaacctcaa cgtccccacc ggcaaactcg tttccctgct cggcccgtcc ggctgcggca
     3541 aaaccacgct tttacgcatt atcgccggac tggaaaacgc cgacggcggc aagattctgt
     3601 ttgatgggca agacgtaacc gccaaacacg tccgcgagcg caaagtcggc ttcgtgttcc
     3661 aacactacgc cctcttccgc cacatgaacg tgtttgacaa cgtcgctttc ggtttgaccg
     3721 tattgcccaa gtccgaacgc ccgtccaaag aacaaatctg cactaaagtc gaagaattgc
     3781 tgaaactcgt acaactctcg catttggcaa aatcctatcc gcaccaactc tccggcgggc
     3841 aacgccagcg catcgccctc gcccgtgcgc ttgcggtcga accgaaactc ctgcttttgg
     3901 acgaaccctt cggcgcgttg gacgccaaag tacgcaaaga attacgcacc tggctgcgcg
     3961 acatccatca caacctgggt gtaaccagca ttctggttac gcacgaccaa gaagaagccc
     4021 tcgaagtttc cgacgaaatc gtcgtgatga accacggcaa aatcgaacaa accggcagcg
     4081 ccgaagctat ttaccgcaaa cccgaaaatg ccttcgttac cgagttcctc ggcgaaaccg
     4141 acgcttttga aggacgtatc gaaaaaggct tctggcatta taacggcttc gcgtggaaat
     4201 tggacgcaca atacaaatgg caggaacaaa ccgccaccgg ctatatccgc ccgcacgaat
     4261 ggcagatcgc cgccgaacac gaaacaccga tgatttgtgc cgaaatcgaa aaagtccacg
     4321 ccgtcggggc attgacgcat attttggtga aacacggcaa acaagacgtg catatcacgc
     4381 tggctggcag cgatgccgcg cgttacccaa tcgccgaagg caaagaattg aagctgattc
     4441 cgaaacaggt ttatgtcttc tctcaaaacg aactgattga atattcgatt taaccatgaa
     4501 agcgcaatgc cgtctgaaag gctttcagac ggcattgtgc tttcaagcgt caggcaagaa
     4561 acagcttgta cgcggcattt tgcgtttcct cgtgatagct gtatcccaga ctttccaaga
     4621 aaccgtcaaa tgcggcggca tcgtgcggcg gcacatcgat accgaccaaa atccgcccgt
     4681 aatccgcacc gtggttgcgg taatggaaga gcgtaatgtt ccaaccgccc tgcatatggt
     4741 tcaaaaaacg cgccaacgcc cccggacgct ccggaaactc aaaactgacc agacgctcgt
     4801 tttctacttt gtccgtccgc cctccgacca tatagcggat atggattttg gcaatctcat
     4861 catcggtcag gtcgacattg ggcaatcccg cctcatccaa ccggctaccg ataaccgcca
     4921 aatcctgcgg acctgccgct tgaagtccga caaagatatg cgctttttca tcgtctccgt
     4981 agcggtagtt gaactcggta atattcctat ttcccaatat attgacaaac ttaaggaagc
     5041 tgccgcgttc ttcggggatg gtaacggcaa aaataccttc gttgccctcg cccaattcac
     5101 tacgctccga cacatggcgc aaacggtgaa aattcatatt cgcaccgctg gtaacggcaa
     5161 tcagggtttg gttttccgcg ccttctcggg cgatataggc tttcagaccc gccaacgcca
     5221 acgcgcccgc cggctcggta atgctgcgcg tgtcatcgaa aatatccttg accgcgccgc
     5281 aaaccgcatc ggtatcgact gtaatgattt catccaaaag ttctttgcag aggcggaagg
     5341 tttcgtttcc gacgactttg accgcagtgc cgtctgaaaa cagcccgaca tctttcaaat
     5401 ggacgatttc acccgcttcg accgactgct tcatacagca ggaatcgttg gtctgaacgc
     5461 cgataacttt gatttcggga cggacctgct tgataaatgc cgccacgccc gccgccaaac
     5521 cgccaccgcc tatcggtacg aatacggcgc ggattggatc gggatgctgg ctgacaattt
     5581 ccatccccac cgtcccctgt cccgcaatca catcaggatc atcaaacggc gcgatatagg
     5641 ttaacccttc tttttccgcc aactccatcg cataatcgta ggcatcgttg tatgaaacgc
     5701 cccgcaaaac cacctcgccg ccacggctct taaccgcatc cactttgatt ttcggcgtag
     5761 tctccggcat aacgataacg gcacggcagc ccaaacgctg tgcggacaat gccacgcctt
     5821 gagcatgatt gcccgcgctt gccgcaatca cgccgcaagc gagcgcatct ttcggcaact
     5881 tggacatttt gttgtacgcg ccgcgtattt tgaacgaaaa aaccggctgc aaatcttcgc
     5941 gtttcaaaag gatgttgttt ttcaaacgta cagaaaggct gcgtgccggt tccaaaggcg
     6001 tttcgaccgc gacatcatag acagatgccg tcaggatgcg gatgaggtaa ttggaataag
     6061 gaaggggcgt gttcataatt caatatggga taatcggttt attaaaatcg caaaacccaa
     6121 aaccatacgc ccaagacggc gcgaaagcaa gaaaaatccg cccgatcaga caccctaagc
     6181 gtataatcgg cagactgaaa cacgcacaca attagaatat ttcatgacag cacataaaat
     6241 cctgcccgtc ctgctttcca tcatcttagg cgtttctcac gcaacggccg catcgcccgc
     6301 gcccaacaaa ccggcggtac acgccgcccc cacgttccaa acacccgaaa ccctcacagc
     6361 ggcacacatc gttatcgacc ttcaaagcag acagacttta tccgccaaaa acatcaatac
     6421 ccctgtcgaa ccggcggcac taacccaact gatgaccgca tatttggttt tcaaaaacat
     6481 gaaatcggga aatatccaat ctgaagaaaa cttaaaaata cccgaatccg catgggcttc
     6541 agaaggaagc agaatgtttg tacgtcccgg cgatacggtc agcaccgaca aactcttaaa
     6601 aggcatgatt gcactatccg caaacgatgc cgccctaacc cttgccggcc ggctgggcaa
     6661 cggctcgatt gaaaattttg tgcaacaaat gaacaaagaa gcccgacgct tgggcatgaa
     6721 gaacactgta ttcaaaaacc cgacaggctt gagtagagaa ggacaggttt ccaccgccaa
     6781 agacctcgcc cagctgtctg aagcattgat gcgcgacttt ccggaatatt acccgctgtt
     6841 ttccatcaaa tctttcaaat tcaaaaatat agagcaaaac aaccgcaata tccttttata
     6901 tagggacaac aatgtaaacg gtctgaaagc cggacacaca gaaagcggcg gctacaacct
     6961 tgccgtgtca tactccggca acggcaggca catccttgtc atcacattgg gttcggaatc
     7021 ggcggaaaca cgcgcatcag acaacagcaa gctgctgaac cgggcattgc aggccttcga
     7081 tacgcccaaa atatatccga aaggcaaaac cgttgcccaa atccaaattt ccggaggcag
     7141 caaaaaaacc gtccgcgcag gcttcctcaa agaagcctac atcactctgc cacataagga
     7201 agcgaaaatg gcagaacaaa ttctagaaac catacagccg attcccgccc cggtaaaaaa
     7261 agggcagatt ttaggaaaaa tcaaaatcag gcaaaacgga tacaccattg ccgaaaaaga
     7321 aatcgtcgca ctggaaaatg taaaaaaaag aagccggtgg caaaggcttt gggcgtgtct
     7381 gacagggcag taatctgccg tttcaaatat cccgtttttc caacaaataa agaaatgccg
     7441 tctgaaacac ggttcagacg gcataaaaca acagggcggt acgtattgca tacgcgccgc
     7501 cctgctgctg aaatcaatta gcgtttctta ccggtaacgg tagcaacagc cagattttcg
     7561 ttacgtttca gggaaacgct ttctacacct tcaggcagtt tgatgtctga caagtgcaga
     7621 atgtcgccgg caaccacttc ggcacaatcc aaatccaaga aagcagggat gttggcaggc
     7681 aaagcaacta cttcaacaga agtgtttaac agagatacgc ggccgccttg cagtttgacc
     7741 gcttgggaat tttcagcgtt aacgatgtgc aggggaacgc ggatgcgtac gggttggtct
     7801 gctttcacag cttggaagtc gatgtgttga acttcgcggc ggaacgggtg catttggaaa
     7861 tcgcggacga taacgtcttt ggtttcaccg ttcagagaca acttaatcaa cgcagtatgg
     7921 aaagattctt tttccaatgc gtagaatacg gttttgtgat ccacagcgat tgcaacaggc
     7981 tcttgacctt caccgtacag aatgccgggg atttggcctt cgcgacgcag gcggcggctc
     8041 gcaccagtgc cttgtgcttc acgaacagag gcttgaattt cataagtcat gttaaatact
     8101 ccaagttagg taaaatcgcc gtcatcggcc gcgaccagct taagacggct tcgggcttat
     8161 ggcagcaaca tgctgcctgt catcacttct tcattgaaaa gatatgagac ggattcttca
     8221 ttgctaatgc ggcggacggt ttcggccaac agaccggcaa tcgttacctg acggatacgg
     8281 tcgcagtttt tagccgcttc agacaaagga atggtatcgg ttacgaccac ttggtcgatt
     8341 tcggatgagg caatacggct gactgcctct ccggagaata cggcgtggct ggcatatgcc
     8401 aagacacgtt ccgccccccg ctctttcaga gcgacggcgg ctttgcacag cgtatttgca
     8461 gtgtcaatca tatcgtccac aatcagacag gttctgcctt gaatatcgcc gatgatgttc
     8521 atgacttccg ccacattggc tttcgggcgg cgtttgtcga tgattgccaa gtcggcattc
     8581 agggattttg ccacggcgcg ggcgcggacg acaccgccga tgtccgggct gacgacggtc
     8641 agattttcaa tccgctgttg tttgatgtcg ttcaacagaa tcggggtggc ataaatattg
     8701 tccaccggaa tatcgaagaa accttgaatc tggtcggcat gcaaatcgac agtcaaaaca
     8761 cggtcgatcc ctgccgaata cagcatattt gccaccagtt tggcagaaat cggaacgcgg
     8821 acggaacgcg gacggcggtc ttggcgcgca tagccgaaat acggaatggc tgtggtaata
     8881 cgacctgccg aagcacgctt cagtgcatcc gccatcgtca ggatttccat caggttgtca
     8941 ttggtcggcg cacaggtcgg ctgaaggatg aaaacatcgc gcccgcgtac gttttccaac
     9001 agttcgacgg caacttcgcc gtctgaaaac ttggatacgg aagcattgcc caaagaaatg
     9061 tccaaatgcc tgacaacacg ttgtgccaat tcgggattgg cattgcctgt aaataccatc
     9121 aaactgtcgt acgcagccat attctcacct gattttatgt ttaacttccg ctcagaaaac
     9181 acaatgcttc cctctgcttg taccaagccc gacattatac ctgcaacatc cgacacaaac
     9241 aaaggcattt caatattttt atttctatga aataaaagcg tgtaagcagg cttacacgct
     9301 tttatttggc tggggaggaa ggattcgaac cttcgcatgc tggaatcaaa atccagtgtc
     9361 ttaaccgctt gacgactccc caaaaagggc tggctgggga ggaaggattc gaaccttcgc
     9421 atgctggaat caaaatccag tgtcttaacc gcttgacgac tccccaactc gtttgacttg
     9481 gctggggagg aaggattcga accttcgcat gctggaatca aaatccagtg tcttaaccgc
     9541 ttgacgactc cccaacaatg tttatacgga caacaaagga tgttttgaaa gaccctctgc
     9601 caaatatgcc tcgtacaaat ctgaaacttg tcggtatata ttgtatgcgc tattcctatc
     9661 ttgacacgcc gtgaatacac acgcaccgga acctgtcatt aaggcaaatc catatcggga
     9721 caactcggaa taggctttcc aaacttcagg gtattcttta aatacaactg cctgcatatc
     9781 atttctaaac ggttgcagat tttggaaagt cggcattatg cttgaggcgg aatttcgtgt
     9841 caagctttcg tgtgtgaaaa tttttgcagt ggaaacgtgg acgggcggtt tgacgatgac
     9901 ataccactgt ttcggaatat ccatttcgtc cagcctgtcg cctatacccc gcgcaaacgc
     9961 atttttgccg aaaataaaaa acggtacgtc cgcccccaga gccgcgcccg aatcaatgag
    10021 ctgccgctgc gtcagaccgc actgccacca acggttcaac accagcaaaa cggttgccgc
    10081 atccgagctt ccgccgccca aacccgcccc tgtcgggatt tttttgtcca gccatatttc
    10141 cacgccggcg gggttgcgcg catatttttg cagcaacgat gcggcacggt agctcaaatc
    10201 tacttcctgc ggcattccat caaccggatt gtgcaggatg attttgccgt cgtccctcgg
    10261 tttcaaatat acggtatcct gcaaatctat caggcagaat atgctttcga tattgtgata
    10321 accgtcttcc cgcctgccgg taatcctcaa atcgagattc agttttgcag gtgcggaaaa
    10381 cgcctgccgt ccgtccgcaa tattcatctg tccgccttat ctcgtgcgcg ccgcacagcg
    10441 ttccggggtt tcggtttcag acggcatacc gatttcggtg aaaaccagcc tgatgttcaa
    10501 atttccgtta ttcagttgca acgttcggac ttgcccccca ctgtcggcgg ttctgccgac
    10561 agtccaaccg tattgttcca atatgccgtc cggcaggatg cggtaaggcg cgcccgccac
    10621 acgcctgcca tctgcccaga tatgcagata ttggattggc agtttgaaac cgaccagctg
    10681 cctgctcaat tcttccgcac tttccgcctg atagacattt cctttgccgt ccactgccaa
    10741 tgcgccgtcc ctgtcttgac acaactgccc gagcgtactg cccaaagggg tattgatatt
    10801 gatggtttcc acgggcggtt ggtatgtcca atcgaaattt gcatacgaac ctttcccttc
    10861 cgctttcact gccaaccgcc cttctgctgc aaaactgctg atgtgttcgg acggctgcca
    10921 caggttttcg ttattttgag gtaattgcgc gcaagcggtc aaaagcagga tgaccgatgc
    10981 ggatacggtg tgtttcatca gaatttcctt aacggatgcc atcctgccgg ccggtggatt
    11041 cggtgtgccg tgcaaaacgc gtgcgaactg cgtgccgttt gcccgaatgc cgcagcttcc
    11101 cggcaaacct tatgccgtct gaaaggatgg acctgcatta tttccggggt ttgcgggaag
    11161 gttggggcaa tgcgatgccg tgacgtttga gcgtttcccg ccatattttc ttgtctcccg
    11221 taaggtgtgc cgcctgcgtc catacgtcaa ccgcctgatc gcgttcgccc aatgcccaca
    11281 acacttcgcc caaatgggcg gcaacttcgg gctcggggtc gttttcaaac gaataccgca
    11341 gatacggcag cgcgctttcc gcgtcgcctt tcaggtaata cgcccagcct atgctgtcgt
    11401 tgacagcggt atcgtccggg ttgatttggt atgccgtctg aagcagggcg aagccttcgt
    11461 ccaaacgttt ggaatcggtc agcaggctgt agcccagatt attcataatc tgagcgttat
    11521 cgggtgcaag cctgaacgcc ctttcaagat ctgaaatcat ttttttccgc ttgccaagcc
    11581 gatcgtaaac aactgaccgc tgtaccaatg cctctgcctg taactctgta ttactgccgg
    11641 caggcggttt ttcgataatc ttgtccaacc ccctcaaagc ctcccgttta tcgggcagct
    11701 tcgacagggc gagcatctgt attttggaca aattgtctgc cgtaaaatac cgcccctgct
    11761 gttcgggaag tttccgcacc ctgccgatct gccgcaaagc cgccctgccg ccgtccaact
    11821 cgacagccgc cgcagccgcc agcacacctt tgtcgaacag gtattccggc gcggacactt
    11881 ttttcaacca ctgcctgact ttggtgtaat cccttcggtc ggcatatatc atcgccgccg
    11941 tcattgccgc cctgccccgc tgttcccccg tccccctgcc gtatgccttt tcggcgtagc
    12001 cgtcgataac ggaagcacct tcttttcggt ttgccgccaa tatcgctgcc tgaatataca
    12061 ggtctgcatt cggattgcgt tccaacagca cgttcaaacg cgcataggca tcatccagcc
    12121 tgtgcaggga aaccagattc ataatttcca tttcctgcca gacggccgaa aggttttggg
    12181 tgtctgtctg ctcgaaaaag ccgtcgagta tttcgggata tttgcgtgca gtcagacgca
    12241 acgtcattaa agtggggggc aatatttccg tatcgagctt cgccaaacgc tgcaaagctc
    12301 cgattgcctt ttcctttttg cgtccctgta cgctgaacac cacatcggca accgccgctt
    12361 cgggcagatg ttcatatttc aacgccgcgc ggcgaaccgc tttcgatgct ttttgcgcca
    12421 acccgtcctg ttgcacggcg gcttgtgcca acaataaaaa caccctgcgg ttctgtcctt
    12481 cgtccgcctg agccagcact tcttccagtc cgtccagatg ctgatttcct ctttccctca
    12541 gcacgttccg cagccacccc gcccgttttt gcgccttacc cggtataggc tcaatctgcc
    12601 gccatttctg ataaatcatt tccgcctgtt caaacgcgtt cagcgacacg gccatttcca
    12661 aggcgcgttc ggcgacttcg ggggattttg tgcgttccaa catcagcata taggttgcca
    12721 gagccgttcc cgcctgcccc ttttgcaagg cggtttcccc tcccagcaac gtaaatatct
    12781 gattaacccg ctcgcccact gccgcaagcc gtgcgcgttc gtttttgatt tcttcctcgc
    12841 tgtaacgctg ctgctttctg aaaacctttc cgacttcctt cggctgtttc atatcccccg
    12901 caccgcctcc ggcggcagat acctgtccgg caatcaaggt tgccgtcaac acagttaaca
    12961 ttttgaaacg gttaggtaac ataatcttcc tttatccgac agccgtccga accttcagac
    13021 ggcatataat caggcgtaac tttatcacaa gcagaatcgt ttgtagattt gcgaaacccc
    13081 gttcaaaaaa ataaatgctg tctgaaacgc aaatccgctt cagacggcat tcccgacgct
    13141 tgcagtttaa gggagtttta tttccaaatt gtcaatcagg cgcgtcgtcc ctagacgggc
    13201 ggcggccaag accaccagtt tcttatctcc cgcccgcgcc acttcgagcg tatcggcgcg
    13261 gcggatttcg acataatcga ccacccagcc cgcagcggtc aaatggtcgg cagcctgccg
    13321 ctccaaacct gcataatcca aactgccctg cgccaaggat tcggcaacag cctttaattc
    13381 gcagtacagg cgcggtgctt cgtcgcgttc cgccgcactc aaatactggt tgcggctgga
    13441 gagtgccaaa ccgtcttccg cgcgccccgt atcgacaggc actatttcaa catcaaaatt
    13501 caaatcctcg gtcaaacctt taatcacggc aagctgctga tagtcttttt tgccgaaaca
    13561 ggcaacatcc ggcgcgacaa tattgaacag cttggacacc accgtcgcca ccccgcggaa
    13621 atgtcccgga cgaaacttgc cgcacaactc attttgcaga ttgggcggtt cgacgttgta
    13681 acgctgttcc acgttcggat agagttcttt ctcatcgggc gcgaaaacaa cggcaacacc
    13741 ctcggcttcc agcttgtccg catcctgttg caaagtacgc ggatatttgt cgaaatcctc
    13801 gccctgaccg aattgcaggc ggttgacgaa aatgctgacc acgacactgt ccgcgcgttt
    13861 tttcgcctca cgcacaagcg caagatgccc ttcatgcaga ttgcccatgg tcggcacaaa
    13921 tgccaccttt cccgcatttt tacgccacgc gcgcagttct cgaatggtat gtatgatttg
    13981 cataacggta atccttatct ttcgggcttc ctgcccgaca aaacgcgccg attatacgcg
    14041 ccgcgcacgg caaaacaaaa tgccgtctga aacggctttc agacggcatc agcagcaaac
    14101 cttgttcagt ctgcaaaaat atgttccgca gcagggaagg ttttggcttt gacttcggca
    14161 acatacgccc gaaccgccgc ctgaatgctg ctttgcccgt gcataaagtt tttgacgaat
    14221 ttcgccgtct tgcccggaaa aataccgagc atatcgtgca tcaccaaaac ctgcccgtcg
    14281 caatcgaccc ccgcgccgat gccgatggtc ggacaggcaa cagtttcagt tacctttttt
    14341 gccagttccg caggaacaca ctccatcaat acaaccgccg cccccgcatc atcgtgcgcc
    14401 ttggcatcgt taagcaaagc ctgcgccttg ccgccgcgcc cctgaacctt atatccgcca
    14461 aaggcaaaca cggattgcgg cgtcagaccg atgtgcgcgc aaaccggaat accgcgcatt
    14521 tgcagaaatt cagtcgtttc cgccatccac acgccgcctt cgagtttgac catatgcgct
    14581 cctgccgcca tcagttcggc ggcggcggca aacgcctgct ccttactctg ctgatatgca
    14641 ccaaacggca aatcgctgac aatcatcgca ttttttgcac cgcgtgctac acattcggtg
    14701 tgatagcaca tatcgcgcag gctgacgggc agcgtcgatt tccgcccttg aaccgccata
    14761 cccaaagagt cgccgaccag cagcatttcc acgccggcat cgtccatcag tgcggcaaaa
    14821 ctggattcgt aagcggtcag catagcgatt ttttcgcccg ccgccttcat tttttgcagt
    14881 gtgttcacag taatcatcag atattgttac cccgcccttt tcagacggcc ttttcagttt
    14941 gaaacgggct attatagtga aatgcccgca gccttgccac cgaccgtgcc gcaaatgcaa
    15001 aacagcccga ctgttttaca caatcggact gtcaaatctg gtgccggcac caagagtcga
    15061 actcgggacc ccctgattac aagtcaggtg ctctaccaac tgagctatac cggcaaagaa
    15121 agcgaattat gcaggcaatg ccgcaccttg gcaaggaatt tatccgaaag ccccggcaaa
    15181 tccgaataag taatttattt gaaaagaaat taatttgaag caggacaacc atcggcattc
    15241 tgataaaata tctgcctttc aaaccgaccg ttcacaccga tggcaagaca tccctaccgc
    15301 cgcctgcgtc ctgcaaaatc cggctttccc gaagtcggca tttccgaaga aggcaatatc
    15361 cgttcgcttc acttgggcag cgacaccatc caaagctcaa tgaacctcga ccacccgtcc
    15421 gagctggtac tctcttacag ccgtgccatg atgggatggc tgctgtttac cgacgctctt
    15481 ccgcagcata tcacccaaat cggcttgggc ggcggttcgt ttgcacgctg gatagacacc
    15541 tacctgcccg acacgcgcca aaccgccgtg gacatcaacc cgcaggtcat cgccattgcc
    15601 cgcagcctgt tcgagttgcc tttcgagggc gagaaatttg aaattatcga agcagacggt
    15661 gcagaatata tcaaagtctt ccgccacaac accgatgtga ttttggtgga cgggttcgac
    15721 ggcgaacaaa tcatcgatgc gctggttgaa gaaccgtttt tccgagactg ccgaaacgca
    15781 ctctcttcag acggcatatt cgtaaccaac tggtggagcg gcgacaaacg ctaccaacgc
    15841 ttcatcgaac ggttgttgag cgtttttgaa gggcgcgtct tggaacttcc tgccgaaagc
    15901 cacggcaatg tcgcggtaat ggccttccaa agcagcccca aagagcaaaa catagacaaa
    15961 ctcaaaaaac gtgccgacaa actgagcaac gcatacggat tggacttcca ccgtatgctt
    16021 gccggcctga aagcgtccaa ccccaacaac ggcaagcatt tccaccttta agcaactatc
    16081 ttcacggctg catcggaaca tgcggaaaat caagaggaaa tcattatgct gaaacccgaa
    16141 accatacaca tatccggtcc tgccggcatt ttagaaacca tccatatccc gtccgaacaa
    16201 gtaccggcac gcggtgttgc cgtcatcaat catcccaacc ccctccaggg cggaacaaac
    16261 accaacaaag ttatccaaac tgccgccaaa gccttaagca aactcggctt ccactgctac
    16321 ctgcccaacc ttcgcggcgt aggcggcagc gaaggcacac acgattacgg acgcggcgaa
    16381 acgcaagact gcctcgccgt catcgactat gcccgtgccc aacatcccga agcccccgaa
    16441 tttgccttat ccggcttctc cttcggcggt tatgtcgcca catttgccgc acaagcgcgc
    16501 atacccgatt tattgctgct catcggcgcg gcagtctgcc actataccgg ccgccccgag
    16561 ccgtccgccg ttcccaatgt tgccaaaacg ctgatgatac acggcgcgga agacgaagtc
    16621 gtcgaaatcg ggaaagcact gaaatgggcg gaaccgcaag atttgcccgt cattaccatc
    16681 gccggttcca cgcatttctt tcacggcaaa ctcatcgtcc tgcgcgacac catcctccgc
    16741 ttcgcgcccg tatgcctgaa cggataaaac ccctttcaga cggcatcgat aatgtaaaac
    16801 ccgtatcggc ggcatccgcc gatacgggtt tgcgttccct ctcattatag gcaaaatccg
    16861 ctgcaaaaca ccctttcccg acccgacaaa ggatctgcaa acgcaatctt ttttgccaat
    16921 agcttcaaag gtttccgata atcctcgctg cccgcttcag acggcacggg atagagcgcg
    16981 tcattcaaca gcggcatacc caaacccatc atatgcacgc gcaactggtg tttcttgccc
    17041 gtatgcggcg taaggcggta aaggctgaat tcccccctgt tttcaatcag ttcgaccgtc
    17101 gtatgtgcgt ttggttcgcc ttccgcctct tgcgtcgtaa aaaatttctc acccctcacc
    17161 aaacgcgaaa ccacatcgag cggatacggc aaatccgtcc ttgtcggcgc aagcgcctca
    17221 tacgttttcc ataccgtttt gttttgaaac atcgtctgat aggctccgcg cgtggcagga
    17281 ttatgcgaca gcagcatcac gcctgccgta tccttgtcca agcggtgcag cggcgtaatg
    17341 tcctcaacat tcaaatgctg caattcaggc cgcaaacgca ggcgcgtgag cagggtttcc
    17401 cgcaaaaacc tgccgctggg gatgacgggc agaaaatgcg gtttgtccac cacaatcaaa
    17461 tgctcatcaa tatgcaaaat cttttcttca aacggaatac gcggctcgct ctcacggctg
    17521 gtttcacggt aataaaacat caccttaccc ggctcgaaca aagaatgttc gtccaacgcc
    17581 gcaccatccg aaccgaccac aaaaccgctg ttcaaccgcc tgcgccaatc gtccgcgccc
    17641 acaaaaggaa agcggatgca cagaaaatgc agcagcggca gcccgtaaaa ctgcttttca
    17701 tgcggcagca ccaaataact gggtttgaca ccgttcaaca gcggaagagg attattgcgt
    17761 tttttcatgc ggcggattgt aaccgttttt cacaaacttt tcagacggca tatcgaaaca
    17821 taattgacaa aaacaaacat attgtttttt atgatttaaa aatttattta gacaagatta
    17881 tcggatattc attattatca gtaaataaga attaatatca ataggagaaa tatgaagcgc
    17941 atctttttgc ccgccatcct gcctttatcc gcttatgccg acctgccctt gacgattgaa
    18001 gacataatga ctgacaaggg caaatggaaa ctggaaactt cccttaccta cctgaatagc
    18061 gaaaacaacc gcgccgaact tgccgcaccg gtttacatcc aaaccggcgc aacctcgttt
    18121 atccccattc cgaccgaaat ccaagaaaac ggcagcaata ccgatatgct cgttggcacg
    18181 ctcggtttgc gctacggact gaccgggaat accgacattt acggcagcgg cagctatctg
    18241 tggcacgaag aacgcaaact cgacggcaac agcaaaaccc gcaacaaacg gatgtccgac
    18301 gtatccctcg gcatcagcca cactttcctt aaagacgaca aaaaccccgc cctaatcagc
    18361 tttcttgaaa gcacggttta cgaaaaatcg cgcaacaaag cctcgtcggg aaaatcctgg
    18421 ctcatcggcg ccaccaccta caaagccata gatccgattg tcctttccct caccgccgcc
    18481 taccgtatca acggcagcaa aaccctttca gacggcatcc gctacaaatc gggcaactac
    18541 ctgctgatca accccaacat ctcatttgcc gccaacgaca gaatcagcct gaccggaggc
    18601 atccaatggc tgggcacaca gcccgaccgc atagacggca aaaaagaaac cgcaagaaac
    18661 acatccacct acgctcattt cggcacaggt ttcggtttca ccaaaaccac ggctttaaac
    18721 gcatccgcac gtttcaacgt ttcagggcaa agcagttccg aactgaaatt tggcgtacag
    18781 catacatttt aagcaggttt tgattttcca accttgtaat ccaaaggagt tattat
//
LOCUS       DAXISH010000042        18356 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.042, whole genome shotgun sequence.
ACCESSION   DAXISH010000042 DAXISH010000000
VERSION     DAXISH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 18356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18356
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.042"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(148..1080)
                     /gene="cysK"
                     /locus_tag="ACFOV4_001415"
     CDS             complement(148..1080)
                     /gene="cysK"
                     /locus_tag="ACFOV4_001415"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFC7619406.1"
                     /translation="MKIANSITELIGNTPLVKLNRLTEGLKAEVAVKLEFFNPGSSVK
                     DRIAEAMIEGAEKAGKINKNTVIVEATSGNTGVGLAMVCAARGYKLAITMPESMSKER
                     KMLLRAFGAELILTPAAEGMAGAIAKAKSLVDAHPDTYFMPRQFDNEANPEVHRKTTA
                     EEIWRDTDGKVDVFVAGVGTGGTITGVGEVLKKYKPEVKVVAVEPEASPVLSGGEKGP
                     HPIQGIGAGFIPTVLNTKIYDSITKVSNEAAFETARAIAEKEGILVGISSGAAVWSAL
                     QLAKQPENEGKLIVVLLPSYGERYLSTPLFADLA"
     gene            complement(1274..1879)
                     /locus_tag="ACFOV4_001416"
     CDS             complement(1274..1879)
                     /locus_tag="ACFOV4_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619407.1"
                     /translation="MILLHLDFLSALLYAAVFLFLIFRAGMLQWFWASIMLWLGISVL
                     GAKLMPGIWGMTRAAPLFIPHFYLTLGSIFFFIGHWNRKTDGNGWQADPEHPLLGLFA
                     VSNVSMTLAFVGICALVHYCFSGTVQVFVFAALLKLYALKPVYWFVLQFVLMAVAYVH
                     RCGIDRQPPSTFGGSQLRLGGLTAALMQVSVLVLLLSEIGR"
     gene            complement(1876..2727)
                     /gene="dapF"
                     /locus_tag="ACFOV4_001417"
     CDS             complement(1876..2727)
                     /gene="dapF"
                     /locus_tag="ACFOV4_001417"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFC7619408.1"
                     /translation="MNTLKFTKMHGLGNDFMVIDAVSQDFIPEHAPIAAWADRFRGIG
                     FDQLLVVGRSETEGVDFRYRIFNADGSEVGQCGNGARCFARFVADKGLTDKKEICVET
                     AKGIIFPKLSDNGMVTVNMGKPKFMPSEIPFVPESGEGDDACIYGVHLESGIQPVSCV
                     NMGNPHAVIVVDDVECAQVRETGSLIEPHRQFPERVNVGFMQIVSRTAIRLRVFERGV
                     GETQACGTGACAAVVAGIRLGLLDEGKTVEVILPGGTLYIEWACGGDVMMTGPAETVF
                     EGELAYS"
     gene            2865..3161
                     /locus_tag="ACFOV4_001418"
     CDS             2865..3161
                     /locus_tag="ACFOV4_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619409.1"
                     /translation="MFRILLLLFPCAILVACTRNIPANPTVSNCAHLQNRTILYFDAH
                     GKPADGAVKGGFYKIIEIQGANCILIQDFNSTGNALGGSYVPDCRKSSLFPKNI"
     gene            3175..3843
                     /locus_tag="ACFOV4_001419"
     CDS             3175..3843
                     /locus_tag="ACFOV4_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFC7619410.1"
                     /translation="MNHDITFLTLFLLGFFGGTHCIGMCGGLSSAFALQLPPHINRFW
                     LILLLNTGRVSSYTAIGLILGLIGQVGVSLDQTRVLQNILYTAANLLLLFLGLYLSGI
                     SSLAAKIEKIGKPIWRNLNPILNRLLPIKSIPACLAVGILWGWLPCGLVYSASLYALG
                     SGSAATGGLYMLAFALGTLPNLLAIGIFSLQLKKIMQNRYIRLCTGLSVSLWALWKLA
                     VLWL"
     gene            complement(3916..6036)
                     /gene="pnp"
                     /locus_tag="ACFOV4_001420"
     CDS             complement(3916..6036)
                     /gene="pnp"
                     /locus_tag="ACFOV4_001420"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFC7619411.1"
                     /translation="MFDKHVKTFQYGNHTVTLETGEIARQAAAAVKVSMGDTVVLVAV
                     TTNKEVKEGQDFFPLTVDYLERTYAAGKIPGGFFKREGKQSEKEILTSRLIDRPIRPL
                     FPEGFYHDIQIVAMVVSVDPEIDSDIPAMLGASAALVLSGVPFAGPIGAARVGYINGV
                     YVLNPTKAELAKSQLDLVVAGTSKAVLMVESEAKILPEDVMLGAVVYGHDQMQAAINA
                     INEFADEVNPEVWDWKAPETNEELVAKVRGIAGETIKEAFKIRQKQARSAKLDEAWNA
                     VKEALITEETDTLAANEIKGIFKHLEADVVRSQILDGQPRIDGRDTRTVRPLNIQTGV
                     LPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTDRFMLHYNFPPYSTGEVG
                     RVGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEITESNGSSSMASVCGGCLS
                     LLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTTEGVTALQM
                     DIKIQGITKEIMQIALAQAKEARLHILDQMKAAVAGPQELSAHAPRLFTMKINQDKIR
                     EVIGKGGETIRSITAETGTEINIAEDGTITIAATTQEAGDAAKKRIEQITAEVEVGKV
                     YEGTVVKILDNNVGAIVSVMPGKDGLVHISQIAHERVRNVGDYLQVGQVVNVKALEVD
                     DRGRVRLSIKALLDAPAREENAAE"
     gene            complement(6273..7136)
                     /locus_tag="ACFOV4_001421"
     CDS             complement(6273..7136)
                     /locus_tag="ACFOV4_001421"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFC7619412.1"
                     /translation="MSEIGLVKIYSGKVRDLYEIDDKRMLMVASDRLSAFDVILDDPI
                     PSKGEILTQISNFWFKKLAHIMPNHFTGQTVYDVLPENEAKVLEKRAVVAKKLTPVKV
                     EAIVRGYLAGSGWKDYQKTGSVCGIRLPEGMQEAQQLPEVIFTPSTKAAVGDHDENIS
                     FEECGRIIGKELAEEVRAKAVRLYTEAAEYAKSRGIIICDTKFEFGLDTNGTLTLMDE
                     VLTPDSSRFWPADQYEVGTNPPSFDKQFVRDWLEQSGWNKKAPAPKVPADVIQKTVEK
                     YREALTLLTQD"
     gene            7335..8210
                     /gene="rfbD"
                     /locus_tag="ACFOV4_001422"
     CDS             7335..8210
                     /gene="rfbD"
                     /locus_tag="ACFOV4_001422"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFC7619413.1"
                     /translation="MRILLTGSKSQLARCLRDRLPEDWETIATDSASLDITDADAVCN
                     MVKSFQPDAIVNTAAYTAVDKAEGDAAAAFAVNASAVYNLALAAHRAHARFIHISTDY
                     IFDGKGKRPYQESDFTNPSNVYGQSKTAGELLALSANPDSLILRTSWLFSEYGDNFVR
                     TMLNLARERSPLSAVHNQIGCPTYAGDLAAAIIRLLQQTSPVRGIYHYAGGKSVSWYE
                     FAQHIFQAASQQQTSFPVPELTAVSDKEYPTAAPRPAYSILDCRKIENDFGIKPSDWQ
                     KALAQVVSKLLSSGY"
     gene            complement(8924..9157)
                     /locus_tag="ACFOV4_001423"
     CDS             complement(8924..9157)
                     /locus_tag="ACFOV4_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /protein_id="HFC7619414.1"
                     /translation="MKLTLMFREYCSLCHKMRDALKPFQNEYGFGLEVVDVDENPVLE
                     EKYNELVPVLLAGDEEICHWFLDEDRLKQFLER"
     gene            complement(9323..9523)
                     /locus_tag="ACFOV4_001424"
     CDS             complement(9323..9523)
                     /locus_tag="ACFOV4_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HFC7619415.1"
                     /translation="MFVCICNAVTDHQIKETIAAGATTMGDLQSQLGVASCCGCCGEL
                     AASFLTAHNAQPTVTAGINVQA"
     gene            complement(9695..10570)
                     /gene="xerD"
                     /locus_tag="ACFOV4_001425"
     CDS             complement(9695..10570)
                     /gene="xerD"
                     /locus_tag="ACFOV4_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFC7619416.1"
                     /translation="MEEGLIDRLLETLWLDRRLSQNTLNGYRRDLEKIARRLSQSGRM
                     LKDADEADLAAAVYVDGEQRSSQARALSACKRLYIWMEREGIRTDNPTRLLKPPKIDK
                     NIPTLITEQQISRLLATPDTDTPHGLRDKALLELMYATGLRVSEAVGLNFGSVDLDRG
                     CITALGKGDKQRMVPMGQESAYWVGRYYTEARPALLKGRSCDALFVSQKKTGISRQLA
                     WMIVKEYAGRAGIGHISPHSLRHAFATHLVQHGLDLRVVQDMLGHADLNTTQIYTHVA
                     NVWLQGVVKEHHSRN"
     gene            complement(10622..11062)
                     /locus_tag="ACFOV4_001426"
     CDS             complement(10622..11062)
                     /locus_tag="ACFOV4_001426"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HFC7619417.1"
                     /translation="MDVKYEFTLPSSSGADFHSAEHLPLVVYFYPKDSTPGCTTEGLD
                     FNARLEQFEALGYTVVGISRDGVKAHQNFCAKQGFRFELLSDKDETVCRLFDVIKLKK
                     LYGKESLGIERSTFVLNKDGEIAHEWRKVKVAGHAQEVLETLSR"
     gene            11383..12321
                     /locus_tag="ACFOV4_001427"
     CDS             11383..12321
                     /locus_tag="ACFOV4_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFC7619418.1"
                     /translation="MSIHTLKRLPSSLLLGLCLSLPSAHLFADNDILGQFLEQNMLTS
                     SDPIEIFAESTIHPTNTQAITGGLILSSQSALVVNNKTGQILYQKNADRIMPIASISK
                     LMSAMVVLDANLDMNETVTITPDEIDRIKGTGSRLAIGTALTRKELLHLSLMSSENRA
                     THALGRTYPGGMGAFVAAMNRKAQSLGMYGSRFYEPTGLNFQNVSTAKDLSLMVNAAA
                     QYPQIRTNSTSNYASVQTKNGQQNYKNSNALVREGMWNIELQKTGYIREAGRSMVVKA
                     NIQNQPVTIVLLNSPTSATRVNDARKIESWMLQQRS"
     gene            12449..12742
                     /gene="hfq"
                     /locus_tag="ACFOV4_001428"
     CDS             12449..12742
                     /gene="hfq"
                     /locus_tag="ACFOV4_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HFC7619419.1"
                     /translation="MTAKGQMLQDPFLNALRKEHVPVSIYLVNGIKLQGQVESFDQYV
                     VLLRNTSVTQMVYKHAISTIVPARSVNLQHENRPQAAPTSTLVQVETVQQPAE"
     gene            12827..13393
                     /locus_tag="ACFOV4_001429"
     CDS             12827..13393
                     /locus_tag="ACFOV4_001429"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC7619420.1"
                     /translation="MLLQNILPFAHCLLRKALPEGGNALDGTAGNGHDTLFLAQTAGI
                     RGKVWAFDIQPQALSRTRCRLKEARYENVQLILDGHENLKQYVSEPLNAAIFNFGWLP
                     GGDKSLTTHTETSIPALCATLSLLKEGGMLIAVLYPGHENGKQEAEAIEQWAKNLPQE
                     QFAVLRYGFTNRKNNPPYLLAFEKLRQK"
     gene            13447..13821
                     /locus_tag="ACFOV4_001430"
     CDS             13447..13821
                     /locus_tag="ACFOV4_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB2 family protein"
                     /protein_id="HFC7619421.1"
                     /translation="MQYLIVKYSHQIFVTVTILLFNIRFFLLWKNPEKPLAGLWKALP
                     HLNDTMLLFTGLWLMKITHFSPFNAPWLGTKILLLLAYIALGMMMMRARPRSVKFYAV
                     YLLAICCVACIVYLAKTKVLPF"
     gene            13831..14325
                     /gene="folK"
                     /locus_tag="ACFOV4_001431"
     CDS             13831..14325
                     /gene="folK"
                     /locus_tag="ACFOV4_001431"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HFC7619422.1"
                     /translation="MNNRHFAVIALGSNLDNPAQQIRGALDALSSHPDIRLEQASSLY
                     MTAPVGYDNQPDFVNAVCTVSTDMDGISLLSLLNRIEADFGRERSFRNAPRTLDLDII
                     DFDGLSSDDPRLTLPHPRAHERSFVIRPLAEILPDFVLGKHGKVAELSKQLGNQGIRL
                     LPDK"
     gene            complement(14452..14931)
                     /locus_tag="ACFOV4_001432"
     CDS             complement(14452..14931)
                     /locus_tag="ACFOV4_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFC7619423.1"
                     /translation="MPESIFKQISLDILKLHRDSVYSLLATSGCNCQVHEAAYVNIDG
                     KYYISLSCEPEVGEVKTGILLIEDESRNLRLSWVGSARELDRKDSVYKSALSALSRKL
                     GRCKDRLHTAVQPFLLELVPEKGRFSVGDEEVWISRNDLVRALYPVGYSMRQAMLQI"
     gene            complement(15151..15888)
                     /gene="ubiE"
                     /locus_tag="ACFOV4_001433"
     CDS             complement(15151..15888)
                     /gene="ubiE"
                     /locus_tag="ACFOV4_001433"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HFC7619424.1"
                     /translation="MGGQKTHFGFSTVNEDEKAGKVAEVFHSVAKNYDIMNDVMSAGL
                     HRVWKHFTINTAHLKKGDKVLDIAGGTGDLSRGWAKRVGKEGEVWLTDINSSMLTVGR
                     DRLLNEGMILPVSLADAEKLPFPDNYFNLVSVAFGLRNMTHKDAALKEMYRVLKPGGT
                     LLVLEFSKIYKPLEGAYDFYSFKLLPVMGKLIAKDADSYQYLAESIRMHPDQETLKQM
                     MLDAGFDSVDYHNMSAGIVALHKGVKF"
     gene            complement(15931..16299)
                     /locus_tag="ACFOV4_001434"
     CDS             complement(15931..16299)
                     /locus_tag="ACFOV4_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF971 domain-containing protein"
                     /protein_id="HFC7619425.1"
                     /translation="MNNIPVEIRLLKNRTVLVLTYGDEPKNLPAEFLRVYSPSAEVRG
                     HGVGQDVLQTGKADVQITDLQPVGQYALKISFSDGHDSGLYDWAYLHRLAYGYDAMWQ
                     EYLDKLAAAGASRFEKQSDC"
     gene            16419..18038
                     /gene="mnmC"
                     /locus_tag="ACFOV4_001435"
     CDS             16419..18038
                     /gene="mnmC"
                     /locus_tag="ACFOV4_001435"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016645 - oxidoreductase activity, acting
                     on the CH-NH group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HFC7619426.1"
                     /translation="MDNLVWDGVPDIRTLDQTIRKHAHPLNLIVCLPDNQIPDFQTAQ
                     DASDAECRLKHRLDQATQCLQFDSINLIEHILPDVRFWLVPPSRTRRLHEHFHHISWQ
                     TEAIPQTESKPDKPWFALPQTSERQKPEHILVIGAGISGAATAHALASHGISVTVLEA
                     RKAAQAASGNRQGLLYAKISPHDTEQTELLLAGYGYTKRLLGHILPESETWGGNGIIH
                     LNYSRTEQQRNHELGLQKHHNHLYRSITPAEAEKIAGIPLNTPYAEPLCGLFWQYGVW
                     LNPPAFVRTLLNHPLIGLHEDTPLTDISHDGEKWIASTPNGIFSATHIIYCTGAHSPR
                     LPETNLAALPLRQIRGQTGLTPSTPFSEQLRCAVSGESYISPSWHGLHCYGASFIPNS
                     SHTGWNEAEEASNRQALAHLNPALSESLFAANPNPQKHQGHAAIRCDSPDHLPLVGAL
                     GDIAAMRQTYTKLALDKNYRIDTPCPYLPNAYVNTAHGTRGLATAPICAAAIAAQILG
                     LPHPFSQRLRHALHPNRTIIRAIVRRKDLTP"
     gene            complement(18152..18269)
                     /locus_tag="ACFOV4_001436"
                     /pseudo
     CDS             complement(18152..18269)
                     /locus_tag="ACFOV4_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215773.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain protein"
BASE COUNT         4703 a         5435 c         3930 g         4288 t
ORIGIN      
        1 tatttccctc aagcaatgcg gcggcaccaa tgcctgatta aaacacaacc ggcgttttcg
       61 gcatatatgc aaaaacgcat tttccggcac ggcgttacac cgataccgaa aaatgcgtct
      121 gaatgtttcg acaatccgat taaagcatta tgccaaatct gcaaaaagtg gcgtagagag
      181 atagcgttcg ccataagaag gcagcagcac gactatcagc ttgccttcgt tttcaggctg
      241 tttggcaagc tgcaacgcac tccaaaccgc cgcaccggaa gaaataccca ccaaaatgcc
      301 ttctttttcc gctattgcgc gggcggtttc aaaagccgct tcgttcgaca ctttggtaat
      361 gctgtcgtaa attttggtat tcaaaacggt cggaataaag cctgcgccga tgccttgaat
      421 cgggtgcggg cctttttcgc cgccgctcaa tacgggtgaa gcttcaggct cgacggcaac
      481 cactttaact tcgggtttgt attttttcaa cacttcgccc acgccggtaa tcgtaccgcc
      541 cgtgccgacg ccggcaacga agacatcgac tttgccgtcc gtatcccgcc aaatttcctc
      601 ggcggttgtt ttgcggtgga cttcggggtt tgcctcattg tcgaactggc gcggcataaa
      661 ataagtgtcg ggatgcgcgt ccaccaagga tttcgctttg gcaatcgcgc ccgccatacc
      721 ttcggcggca ggggtcagaa tcagctccgc accaaacgcg cgcaacagca ttttgcgctc
      781 cttactcatg ctttccggca tggtaatcgc cagcttgtag ccgcgtgcgg cacataccat
      841 tgccaaaccg acacccgtat tgccgctggt tgcttcgaca atgacggtgt ttttgttgat
      901 tttgcccgct ttttcggcac cctcgatcat tgcttcggca atgcggtctt tgacgctgct
      961 gcctggattg aaaaattcca gtttcacggc aacctccgcc ttcaaacctt cggtcagacg
     1021 gttcagtttg accaaaggcg tgttgccgat tagttcggtg atgctgtttg caattttcat
     1081 cttctgctcc tgaataataa ggtttcgaca gtaaggcgca atccccatag gcatcctgtc
     1141 cgattgcagg ggatttgcgc cgaaacataa acaaatttcg gatatggctt tatcctaaac
     1201 ctatgccgcc taaaaaacca atatccaaaa tttctttctt tataactttt tgttccgata
     1261 cggccgcacc gtattatctt ccaatttctg aaagcagcag caccagtacc gagacctgca
     1321 tcaacgctgc cgtcaacccg ccgagtcgca gctgcgagcc gccgaacgtt gacggcggct
     1381 gccggtctat accgcagcgg tggacatagg caaccgccat cagcacaaac tgcaacacga
     1441 accaataaac cggcttcagc gcataaagtt tgagcagtgc cgcaaacaca aacacttgaa
     1501 ccgttcccga aaagcaataa tgcaccaacg cacatattcc gacaaaagca agcgtcatcg
     1561 atacattact gacggcaaaa agcccgagca gcggatgttc ggggtctgcc tgccatccgt
     1621 ttccatccgt tttccggttc caatgcccga tgaaaaaaaa tatgctgccc aaagtcaggt
     1681 aaaaatgggg gatgaacaag ggcgcggcgc gggtcattcc ccatatgccg ggcatcagct
     1741 ttgcccccaa aaccgatatg cccagccaca gcataatact cgcccaaaac cattgcaaca
     1801 ttcctgcgcg gaatatcaga aacagaaaaa ccgccgcata cagtaaggca gacaaaaaat
     1861 ccaaatgcag caaaatcatg aatacgccaa ctcgccttca aacaccgttt ccgcagggcc
     1921 ggtcatcatc acatcgccgc cgcaggccca ttcgatatat aaagttccgc ccggcaaaat
     1981 cacctctacc gttttccctt catccaacaa ccccagacgg atacccgcca ccacagccgc
     2041 acacgcgccc gtaccgcacg cttgggtttc gcccacgccg cgctcgaaca cgcgcaaacg
     2101 aatcgcggtt cggctgacaa tctgcataaa gccgacgttg acgcgttcgg gaaactgcct
     2161 gtgcggttcg ataagcgaac cggtttcgcg cacctgcgcg cattctacgt catcgaccac
     2221 aatcaccgca tgggggttgc ccatattgac gcagctgaca ggctgaatgc cggattcgag
     2281 atgcaccccg taaatacagg catcatcccc ctcgcccgat tcggggacaa acggtatttc
     2341 agacggcata aacttcggtt tgcccatatt gaccgtaacc atgccgttat cggacaattt
     2401 cggaaaaata atgcccttgg ccgtttcaac acaaatttct ttcttatcgg tcaaaccctt
     2461 gtctgcaaca aaacgggcaa aacaacgcgc tccgttgccg cattgcccga cctcgctgcc
     2521 gtcggcattg aaaatacggt aacggaaatc cacaccttcg gtttccgaac gcccgaccac
     2581 caaaagctgg tcgaacccga tgccgcggaa acggtcagcc catgctgcaa tcggtgcatg
     2641 ctcaggaata aaatcctgac tgaccgcgtc aatcaccata aaatcgttgc ccaaaccgtg
     2701 cattttagta aatttcaaag tgttcatatt attctgaaat cccgtattat ctgttgcttc
     2761 cgaattccga aatcccccgc accgaaggga aatgcttcca tctcccgccg cctgaggatt
     2821 aaaatcagcc attatactgt ttgttacccc ttacaagaaa caccatgttc cgcatattac
     2881 tgttgctttt cccttgtgca atccttgtcg cctgcacccg aaacataccg gcaaacccga
     2941 ccgtttcaaa ttgcgcgcat cttcaaaacc gcaccatcct gtattttgac gcacacggca
     3001 aacccgccga cggcgcagta aagggcggat tttacaaaat tatcgaaata cagggtgcaa
     3061 actgcatcct tattcaagac tttaacagca cgggcaatgc cctcggcgga tcctatgtgc
     3121 cggactgccg caaatcatcc cttttcccga aaaatatttg acttcaaact gcctatgaac
     3181 cacgacatca ctttcctcac cctgttcctg ctcggcttct tcggcggaac gcactgcatc
     3241 ggcatgtgcg gcggattaag cagcgcgttt gcgctccaac tccccccgca tatcaaccgc
     3301 ttttggctga tcctgctgct taacacagga cgggtaagca gctatacggc aatcggcctg
     3361 atactcggat taatcggaca ggtcggcgtt tcactcgacc aaacccgcgt cctgcagaat
     3421 attttataca cggccgccaa cctcctgctg ctctttttag gcttatactt gagcggtatt
     3481 tcttccttgg cggcaaaaat cgagaaaatc ggcaaaccga tatggcggaa cctgaacccg
     3541 atactcaacc ggctgttacc cataaaatcc atacccgcct gccttgcggt cggaatatta
     3601 tggggctggc tgccgtgcgg actggtttac agcgcgtcgc tttacgcgct gggaagcggt
     3661 agtgcggcaa cgggcgggtt atatatgctt gcctttgcac tgggtacgct gcccaatctt
     3721 ttggcaatcg gcattttttc cctacaactg aaaaaaatca tgcaaaaccg atatatccgc
     3781 ctgtgtacgg gattatccgt atcattatgg gcattatgga aacttgccgt cctgtggctg
     3841 taagccccat tcattcccga tacccgtaaa aaataccgtc tgaaacctgt tcagacggca
     3901 ctttcaccct aagcgttact cggcggcatt ttcctcacgg gcaggcgcgt ccagcagggc
     3961 tttgatggac aggcgcacac ggcctctgtc atccacttcc aatgctttca cgttcaccac
     4021 ctgaccgact tgcaggtagt caccgacatt gcgtacgcgc tcgtgggcga tttggctgat
     4081 gtgtaccaaa ccgtctttgc ccggcatcac gctgacaatc gcgccgacgt tgttgtcgag
     4141 gattttcacc acagtgcctt catacacttt gcccacttcc acttcggcag taatctgctc
     4201 gatacgtttt ttcgccgcat cgccggcttc ttgagtggtc gcagcaatgg taatcgtacc
     4261 gtcttcggca atattgattt ccgtaccggt ttcagcggta atcgaacgga tggtttcgcc
     4321 gcccttaccg ataacttcgc ggattttgtc ttggttgatt ttcatcgtaa acaaacgcgg
     4381 cgcgtgtgcg gacaactctt gcgggcccgc aacggcggct ttcatctgat ccaagatgtg
     4441 cagacgcgct tctttggcct gtgccaaagc gatttgcata atttctttgg taatgccttg
     4501 gattttgatg tccatttgca gcgcggtaac gccttcggtc gtaccggcca ctttaaagtc
     4561 catatcgccc aagtggtctt cgtcgcccaa aatgtcggtc aggacggcaa atttgttgcc
     4621 ttccagaatc agacccatcg cgataccggc aacgtgtgct ttcaaaggca cgccggcaga
     4681 cagcaggctc aggcagccgc cgcagacgga agccatagag gaagagccgt tggattcggt
     4741 aatttcggag accacgcgca tggtgtagct gaaatcttca ggtttcggca atacggccaa
     4801 caatgcacgt ttagccaaac ggccgtgacc gatttcacgg cgtttcggcg cacctacgcg
     4861 acccacttct ccggtagagt acggcggaaa gttgtagtgc agcatgaagc ggtcggtgta
     4921 ttcgccggac agcgcgtcaa tgatttgctc gtcgcgcgaa gtacccaaag ttgcaaccgc
     4981 caaagcttgg gtttcgccac gggtaaacaa tgcggaaccg tgtgtacgcg gcaatacgcc
     5041 ggtttggatg ttcaaaggac ggacggtgcg ggtgtcgcgg ccgtcgatgc gcggttgacc
     5101 gtccaaaatt tggctgcgga caacatcggc ttccaagtgt ttgaaaatac ctttgatttc
     5161 gttggcggcc aaagtatcgg tttcttcggt aatcaaggct tcttttaccg cattccaagc
     5221 ctcgtccaat ttggcggaac gcgcttgttt ttgacggatt ttgaacgctt ctttaatggt
     5281 ttcgccggca atcccgcgga ctttggcaac taattcttca ttggtttcag gtgctttcca
     5341 atcccaaact tccggattga cttcgtcggc aaattcattg atggcgttaa tcgccgcctg
     5401 catttgatcg tggccgtaaa ccaccgcgcc caacatcacg tcttcgggca ggattttggc
     5461 ttcggattcc accatcaaca cggctttgga cgtaccggcg accaccaagt ccaattgcga
     5521 tttagccaat tcggctttag tcgggttcaa aacgtacacg ccgtttatat aacccacgcg
     5581 tgccgcacca atcggaccgg caaacggtac gccgctcaac accagcgcgg cagacgcgcc
     5641 caacattgca ggaatgtcgg aatcgatttc gggatcgacg gacacgacca tcgctacgat
     5701 ttggatgtcg tggtagaaac cttcggggaa cagcggacga atcgggcggt cgatcagacg
     5761 gctggtcagg atttcttttt cgctttgttt gccttcgcgt ttgaagaaac cgccggggat
     5821 tttacctgcg gcgtaagtgc gttccaaata atcgacggtc agggggaaga agtcttgacc
     5881 ttctttcact tctttgttgg tggtaacggc aaccaaaaca acggtgtcgc ccatagagac
     5941 tttaacggca gcggcggctt ggcgggcaat ttcgccggtt tccaaagtaa cggtgtggtt
     6001 gccgtattgg aaagttttaa cgtgtttgtc gaacattatt gttcctttca aaataccgca
     6061 ctgctaaaac actaataatg cacactaaaa tccgaatgtg catagttagg gtttcagacc
     6121 gtgcggcagg ttgtaaacaa gctttcagac gacatttcgg acgctgaaag caattgcgga
     6181 ttataaaggc aaccatcctt aaaatccagt attgatacaa taaaaaggcc gtctgaaaca
     6241 tatctctttc agacggcctt caaacttaaa aatcaatcct gagtcagcaa agtcaatgct
     6301 tcccgatact tctcgacagt tttctgaatc acatcggcag gcactttcgg cgcaggggct
     6361 tttttgttcc aaccgctttg ttccagccag tcgcggacga attgtttgtc aaaagacggc
     6421 ggattggtgc cgacttcata ttgatccgcc ggccagaagc ggctcgaatc gggagttaat
     6481 acctcatcca tcagcgtcag cgtaccgttt gtatccaaac cgaattcaaa tttggtatcg
     6541 caaataataa taccgcgcga tttggcatat tccgccgctt cggtgtaaag ccgaaccgcc
     6601 ttggcgcgca cttcttccgc caattctttg ccgataatgc gtccgcattc ttcaaagctg
     6661 atgttttcat cgtgatcgcc gactgcggct ttggtcgatg gcgtaaaaat cacttcaggc
     6721 agttgttgcg cttcctgcat accttcgggc agccgaatac cgcaaaccga gccggttttt
     6781 tgataatctt tccaaccgct gcctgccaga taaccgcgca caatcgcctc tactttcacc
     6841 ggagtgagct ttttagccac gacggcgcgt ttttctaaaa ctttggcttc gttttcaggc
     6901 aaaacatcgt aaaccgtttg accggtaaag tggttgggca taatatgcgc cagtttttta
     6961 aaccaaaaat tggaaatctg cgtcagaatc tcccctttgc tcggaatcgg gtcgtccaaa
     7021 atcacatcaa acgcggacag gcggtcggaa gcgaccatca gcatacgttt atcgtcgatt
     7081 tcatataaat cgcgcacttt tccagaatag atctttacca aaccaatctc actcatttcg
     7141 ccccccctga aaatatcttg aaaataccga cccgacaccc gacaggtttg aatcgcaaac
     7201 cgatattcta gccgaagtcg gcgcaaaaca atacccatgg cacaaaaagc caacccgtca
     7261 accgtcggca aagttttggc actataatac cgacagcaag tcctacaata cacttttacc
     7321 aaaggaaata cctcatgaga atcctattga caggctcgaa aagccaactg gcacgctgcc
     7381 tgcgcgaccg tcttccggaa gactgggaaa ccattgcgac ggattccgca tccctagaca
     7441 ttaccgatgc cgatgccgtc tgcaacatgg tcaaaagttt ccaacccgac gccattgtca
     7501 acacggctgc ctatactgcc gtcgacaaag cggaaggcga tgcggcagcg gcatttgccg
     7561 tcaatgcttc cgccgtttac aaccttgcct tggcagcaca tcgcgcccat gcccgattca
     7621 tccacatctc aaccgactat atctttgacg gtaaagggaa aaggccctat caggaaagcg
     7681 actttaccaa tccttccaat gtatacggac aatccaaaac cgccggcgaa ctgctcgcac
     7741 tgtctgccaa tcccgacagc cttatcctgc ggacttcttg gctgtttagc gaatacgggg
     7801 acaactttgt ccgcaccatg ctgaaccttg cgcgggaacg ttccccgctg tccgccgtcc
     7861 acaaccaaat cggctgcccg acctatgccg gcgacctggc tgccgccatc atccgccttt
     7921 tgcagcaaac gtcgcccgtg cgcggcattt accactacgc cggcggcaaa tccgtatcct
     7981 ggtacgaatt tgcccaacat attttccaag cggcatcgca acagcagaca tccttccccg
     8041 ttcccgaatt gactgccgtt tcagacaagg aatatccgac cgccgccccc aggcccgcat
     8101 acagcatttt ggactgccgc aaaatcgaaa acgacttcgg catcaaaccg tcagactggc
     8161 agaaagccct tgcacaggtc gtttccaagc tgctctctag tgggtactag atataatgca
     8221 gcatccgata aagtaaagcc ccgaagtggc agcttcgggg cttatcggat agaaaggagg
     8281 cttgaagaaa tggcgaaagt tattttattc ctgtttcttt tgttagtttg ctcgccagcc
     8341 tactaatgaa aaactgaaat aacaaggggt ggcaaattac cgcgcccctt tcgccaacct
     8401 ttcttcgagc cattttacta caatggtttt aaaaatcaag gattgcctga tgccgcccgc
     8461 ccctctgttt cctccgtcaa gcaccgcctt ggcggttttc ttatatagtg gattaacaaa
     8521 aaccagtact gcgttgcctc gccttgccgt actatttgta ctgtctgcgg cttcgtcgcc
     8581 ttgtcctgat ttttgttaat ccactataaa atctaccgat tacacaaaca catatcatct
     8641 ttacacaatc atgcttccat caacagtaaa acatgatatg attgccaaca ataacatctc
     8701 acaataaatt ttctaatttt tattgaaaaa atcaataaat aagaattctc ccaaccgaca
     8761 aataaaataa agaaagggtt aatatgcaac atcgaagaag actagcaatt taccaagcat
     8821 ccaaacgtgc ttcctttacc ggcaggtcat cagccccgca aaaacgtaaa gaacgttaat
     8881 ttgaaaaaaa tgccgtctga agtctgcttc agacggcatt tttttaccgt tcgagaaact
     8941 gtttcaacct gtcctcatcc aaaaaccagt ggcagatttc ctcatctccc gccaacaaaa
     9001 cgggaaccag ctcattgtat ttttcttcca aaacaggatt ttcatccaca tcgaccactt
     9061 ccagcccgaa cccgtattca ttttgaaaag gtttgagtgc atcgcgcatt ttgtggcaca
     9121 agctgcaata ttcacgaaac atcaaggtca atttcatccg cgtttcctta tctgtcaatt
     9181 tgcacacgcc aaagccttag acgcagcaga atcatggtct atttgggaaa aaacaatgtt
     9241 ttcaaggaag atgatactca agtcctgcca aaaacagcaa aaatgccgtc tgaacagttc
     9301 agacggcatt tccaaaaccg ttttacgctt gaacattgat acccgccgta accgtcggtt
     9361 gcgcattgtg cgccgtcaga aacgaagcgg caagctcccc acagcagccg cagcagctcg
     9421 ctacgcccaa ttgcgactgc aaatcgccca ttgtggtcgc gccggcggcg atggtttcct
     9481 tgatttgatg gtcggtaacg gcattgcaga tgcagacaaa cattttgtgc tccgtgtgtt
     9541 ctcaaactat cgtaccgata gcggctttta ttatcgtatg cgaatataaa taaaaacggt
     9601 tcgcattgca aggtcggcat acacggtttg tcttggtaat tttttatcaa gtttgcattt
     9661 tcgattgatt tcttattaaa ccgaagcaga agcctcagtt tcgggaatgg tgttccttca
     9721 ctacaccctg caaccataca ttggcaacat gggtataaat ctgcgtcgta ttcaaatcgg
     9781 catgtcccaa catatcctga accacgcgca aatccaatcc gtgctgcacc aagtgcgtgg
     9841 cgaaggcatg gcgcaggctg tgcgggctga tgtgcccgat gcctgcccta cctgcatatt
     9901 ctttgacaat catccatgcc aactgacggg aaatacctgt ttttttctga ctgacaaaca
     9961 aggcatcgca actcctgccc ttcaacaagg ccggacgcgc ctccgtgtaa tagcgtccca
    10021 cccaatacgc cgattcctgc cccatcggga ccatcctctg cttatcgccc ttgcccagcg
    10081 cggtaataca gcccctgtcc aaatccacac tgccgaaatt cagcccgacc gcctcgctga
    10141 cgcgcaagcc ggtcgcgtac atcaattcga gcagtgcctt gtcccgcaaa ccgtgtggcg
    10201 tatcagtatc cggagtggca agcagccggg aaatctgctg ttctgtaatc agtgtcggaa
    10261 tattcttgtc gattttgggc ggtttcagca aacgggtggg attgtccgtc cttatgcctt
    10321 cacgctccat ccatatatac aggcgtttgc acgccgataa tgcgcgcgcc tgcgaactcc
    10381 gttgctctcc gtcaacataa accgccgccg ccaaatccgc ttcgtccgca tccttcagca
    10441 ttctgcccga ttgggacagg cggcgggcga ttttttccaa atcgcgccgg taaccgttta
    10501 aagtattctg actgagccgc ctgtccaacc acagcgtttc aagcagcctg tcgatcaaac
    10561 cttcttccat accgttccaa acaaatgccg tctgaatctt cttcagacgg catggttcac
    10621 attatcggga aagcgtttcc aatacttcct gcgcgtgacc cgccactttg actttccgcc
    10681 attcatgggc gatttctcca tccttattca agacgaacgt actgcgctcg atacctaacg
    10741 actctttccc gtacagtttc ttcaatttga tgacatcaaa caggcggcac actgtttcat
    10801 ccttgtcgct caacagctcg aaccggaaac cctgcttggc gcaaaaattc tgatgcgcct
    10861 ttacgccgtc gcgggaaata ccgaccacgg tataacccaa tgcctcaaac tgttccaaac
    10921 gcgcattgaa atccaagcct tccgtcgtac agcccggcgt actgtctttc ggataaaaat
    10981 acacgaccaa aggcagatgt tctgccgaat gaaaatccgc accgctgctc gaaggcaggg
    11041 taaattcata tttcacatcc atagtcctac tcccgatatt cccattattc aaaacggcac
    11101 gcagacgcac cgccgcaatt gccaaaccaa ccccgattct accgccccaa aggacaagga
    11161 ttcaaccgcc ggaaacatcc aaaccgacac acgacggcat gaaaaatatc catgtcaaac
    11221 cacaaaatat gttccgattt aaaaacagaa tgttataaaa cccaatcccc aaaacacaac
    11281 aagaccgccc gcctacgggc agtctcctgt cagacgacat actttacaga tggctgtttt
    11341 ttcaacaaaa taacgccaat actcaaaaat atggaatcaa aaatgtccat ccatactctg
    11401 aaacgcctgc cctcatcgct gctgctcggt ctctgccttt ccctgccgtc agcccacctt
    11461 tttgccgaca acgacatttt agggcaattt ttagaacaga acatgcttac ctcctccgat
    11521 ccgatagaaa tattcgccga aagcacgata caccccacca acacccaagc cattacaggc
    11581 ggtctgattc tctcctcaca gtctgccctg gtcgtcaaca acaaaaccgg acagatactg
    11641 tatcagaaaa acgccgacag gattatgccc atcgcctcca tttccaaact gatgagcgcg
    11701 atggtcgttt tggatgcaaa cttggacatg aacgaaaccg ttaccattac gcccgacgaa
    11761 atcgaccgca tcaaagggac cggcagccgt cttgccatag gtacggcact tacacgcaaa
    11821 gaactgctgc acctgagcct gatgagcagc gaaaaccgcg ccacccatgc attgggcaga
    11881 acctaccccg gcggcatggg cgcatttgtc gccgccatga accgcaaagc ccaaagcctc
    11941 ggtatgtacg gcagccgctt ttacgaaccg accggactca acttccaaaa cgtttccacc
    12001 gccaaagacc tgagccttat ggtcaacgcc gccgcccaat atccgcaaat ccgcaccaac
    12061 tcgacttcca actacgcctc ggtacagacc aaaaacgggc agcagaacta caaaaactcc
    12121 aatgccctgg tcagagaagg catgtggaac atcgaattgc agaaaaccgg ctacatacgc
    12181 gaagcaggca ggtctatggt tgtcaaagcc aacattcaaa atcaacccgt taccatcgta
    12241 ttgctgaact cgcccacatc cgccacacgc gtcaacgacg cccgcaaaat cgaatcgtgg
    12301 atgctgcagc aacgctcctg acatacaaat gcccggcgga aaaccgccca aacacaaaaa
    12361 aattggtaat ttttcctatt caaggctaca attcgacacg cacagggcgt ctgcccgatt
    12421 tcacaatcat aataacggag ttaaaaatat gacagctaaa ggacaaatgt tgcaagatcc
    12481 cttcctgaac gccctgcgta aagagcacgt tccggtttcg atttacttag ttaacggtat
    12541 caaattacaa ggtcaggttg agtctttcga tcaatacgtt gttctcctga gaaacacttc
    12601 cgtcacccaa atggtttaca aacacgccat ttccaccatc gtaccggcac gctccgtcaa
    12661 cctacaacat gaaaacagac cccaagccgc accgacttcg accctcgtcc aagtggaaac
    12721 cgtccagcag cctgccgaat aatccgcacg aagcatgacg tgtcatatct ttcaatacct
    12781 taccggacaa cggtaaggta tttttatttt cagacagcat ttaaaaatgt tattgcaaaa
    12841 catccttcca ttcgcccatt gccttttgcg gaaggcactt cccgaaggtg gcaatgcttt
    12901 ggacggcacc gccggcaacg gacacgacac ccttttcctc gcacaaaccg caggcatccg
    12961 ggggaaagtg tgggcattcg acatccagcc gcaagccctg agccgcactc gatgccgtct
    13021 gaaagaagcg agatacgaga atgtgcaact catcttagac ggacacgaaa acctgaaaca
    13081 atatgtttca gaaccactaa atgccgccat tttcaacttt ggctggctgc ccggcggaga
    13141 taaaagcctt accacccata cggaaaccag cattcccgcc ctttgcgcaa ccctctccct
    13201 gctgaaagaa ggcggtatgc ttattgccgt cctctatccg ggacacgaaa acggcaaaca
    13261 ggaggcagaa gcaatcgaac aatgggcaaa aaacctgcct caagaacagt ttgccgtttt
    13321 gcgttacggc tttaccaacc ggaaaaacaa cccgccctat ctgttggcat ttgaaaagtt
    13381 acgtcaaaaa taaatgtttg cggtaaaata agccgattcc aacccttatt ttgataagag
    13441 ccgactatgc agtatctgat tgtcaaatac agccaccaaa tcttcgttac cgttaccatt
    13501 ttgttgttca acatccgctt tttcctgctt tggaaaaatc ccgaaaaacc tttggcgggc
    13561 ttgtggaagg cactgcccca cctcaacgac acgatgctgc tgtttacggg attgtggctg
    13621 atgaaaatca cccatttctc cccgttcaac gcgccttggc tcggcacaaa aatcctgctt
    13681 ctgctcgcct atatcgcatt gggtatgatg atgatgcgcg cccgcccccg ctcggtcaaa
    13741 ttctatgccg tttacctgct tgccatttgt tgcgtcgcct gtatcgttta ccttgccaaa
    13801 accaaagtcc tgccattctg aaacactgcc atgaacaaca gacattttgc cgtcatcgcc
    13861 ttgggcagca accttgacaa ccccgcacaa caaatacgcg gcgcattgga cgcgctctcg
    13921 tcccaccccg acatccggct tgaacaggct tcctcactgt atatgaccgc gcccgtcggt
    13981 tacgacaatc agcccgattt cgtcaatgcc gtctgcaccg tctccaccga tatggacggc
    14041 atctcgctgc tctctttgct caaccgtatc gaggcggatt tcgggcgcga acgcagtttc
    14101 cgaaacgcgc cgcgcacatt ggatttggac atcatcgact ttgacggcct atccagcgac
    14161 gacccccgcc tcaccctgcc gcatccgcgc gcacacgaac gcagtttcgt catacgccct
    14221 ttggcagaaa tcctccctga ttttgtttta ggaaaacacg gaaaagttgc cgaattgtca
    14281 aaacaactgg gcaatcaagg tatccgtctt ttaccggata agtaattccg cacgcggatg
    14341 ccgtctgaat gccggtttca gacggcattt ttcctttgcc gccaacacgc gtgcaaaaaa
    14401 atcgcccctt ggaaaagggg cgcaaaagga acacaaacca ctaccaaaac tttaaatctg
    14461 caacattgcc tgccgcatac tgtatccgac aggatataaa gccctcacta aatcgtttcg
    14521 agaaatccaa acttcttcat cgccgacaga aaatctgcct ttctccggca ccagctccaa
    14581 caaaaacggt tgaaccgccg tatgcagcct gtccttacac cgccccagct ttctggacaa
    14641 ggcggacagg gcactcttat agacactatc cttgcggtca agttcccgcg cactgccgac
    14701 ccagctcaaa cgaaggttgc ggctttcatc ctcaatcagc aaaatgcctg ttttgacttc
    14761 ccccacctct ggctcgcatg aaagcgaaat ataatatttg ccgtcgatgt tgacatacgc
    14821 cgcctcatgc acctgacagt tgcagccgga agtggcaagc agcgaataaa cagaatcccg
    14881 atgcagtttc aaaatatcaa gggaaatctg tttgaaaata ctttccggca tttttccctc
    14941 ctttcgtctg ctgcgttgtt tactggattg actgcattat acagacatct cccaatcttg
    15001 caaatgataa ttgttcctat tttttaaaaa atttataaat tattgataga tatgtgaatt
    15061 aattttaaga tttaaaatct ctttctcaaa aaaacacaaa aatgccgtct gaaacgtgtt
    15121 cagacggcat tggctgcaca ggcaatccgt ttaaaatttc acgcccttat gcagcgcaac
    15181 gatccccgca ctcatattat gatagtccac actgtcaaat ccggcatcca gcatcatttg
    15241 ctttaaagtt tcctgatcgg ggtgcatacg gatggattcg gcgagatact ggtagctgtc
    15301 cgcatctttg gcaatcagtt tgcccatgac cggcagcagc ttgaacgaat agaaatcata
    15361 cgcgccttcg agcggcttgt agattttgga aaactccaac accagcaacg tgccgccagg
    15421 tttcaaaaca cgatacatct ctttcagcgc ggcatcttta tgcgtcatgt tccgcaagcc
    15481 gaacgccacg gaaactaagt tgaaataatt gtcagggaaa ggcagttttt ccgcatcggc
    15541 aagcgacacg ggcaaaatca tgccttcgtt caacagacgg tcgcgcccga cggtcagcat
    15601 agaggaatta atatcggtca gccaaacctc gccttccttg ccgacccgtt tcgcccaacc
    15661 gcgcgacaaa tcgcccgtac cgcccgcaat gtccaacact ttatcgcctt ttttcaggtg
    15721 cgccgtgttg atggtgaaat gcttccacac cctgtgcagc cctgccgaca tgacatcatt
    15781 cataatgtcg tagtttttgg cgacggagtg gaacacttcc gccactttgc cggctttttc
    15841 atcttcgttg accgtgctaa acccgaaatg cgttttttgt ccgcccatat tctaaccacc
    15901 tccctgatac cgccctacgg catcccaaac ttaacaatct gattgctttt caaaacgcga
    15961 cgcgcccgcc gccgccaatt tgtccaaata ttcctgccac atcgcatcgt atccgtatgc
    16021 cagtctgtgc agatacgccc aatcgtaaag accgctgtcg tgcccgtccg aaaaactgat
    16081 tttcagcgcg tactgtccga caggctgcaa atccgtaatt tgcacatctg ccttaccggt
    16141 ctgcaaaaca tcctgtccca caccgtgtcc gcgcacttcc gcactcggcg aatagacgcg
    16201 taaaaattcg gcaggcagat ttttaggttc gtccccataa gtcaaaacca acacggtacg
    16261 gtttttcaac aaacggattt caacaggaat attattcaaa aaacacctcg gttcggcata
    16321 caatatccgg caggcgcagg cgtgccttca aacggcgcgt attttaacag ctttatcccg
    16381 ataccgatat tcaaacccac actttaaacg gcattgatat ggacaatctc gtatgggacg
    16441 gcgttcccga catccgcaca ctcgaccaaa ccatccgcaa acacgcacac ccgctcaacc
    16501 tgattgtctg cctccccgat aatcagattc ccgattttca aaccgcacaa gatgcttcgg
    16561 acgcggaatg ccgtctgaag caccgtttgg atcaggcaac gcagtgcctc cagttcgaca
    16621 gcatcaacct catcgaacac atcctgcccg atgtccgctt ctggctggtt cccccttcac
    16681 gcacccgccg cctgcacgaa cacttccacc acatttcctg gcagaccgaa gccatcccgc
    16741 aaaccgaaag caaacccgac aaaccctggt ttgcacttcc acaaacatcc gaacggcaaa
    16801 aaccggaaca catcctcgtt atcggcgcgg gcatatccgg cgcggcaacc gcccacgcct
    16861 tagcatcaca cggcatttcc gttaccgtat tggaagcccg aaaagccgcc caagccgcca
    16921 gcggcaaccg ccaagggctg ctctacgcca aaatctcgcc gcacgacacc gaacaaaccg
    16981 aactgctgct tgccggctac ggctacacca aacgcctgct cggacacatc ctgcccgaat
    17041 ccgaaacctg gggcggcaac ggcatcatcc acctcaatta cagccgcacc gaacaacaac
    17101 gcaatcacga attgggtttg caaaaacacc ataaccacct ctaccgcagc atcacgccgg
    17161 cagaagccga aaaaatcgcc ggcatcccgc tgaacacgcc ctacgccgaa ccattatgcg
    17221 gactgttttg gcagtacggc gtatggctca atccacccgc attcgtccgc accctcctca
    17281 accatccgct cattggacta cacgaagaca caccgttaac cgacatttcc cacgacgggg
    17341 aaaagtggat tgcaagcacg ccaaacggca tattttccgc cacacacatc atctactgca
    17401 ccggcgcgca cagccctcgc ctgcccgaaa ccaacctcgc cgccctgcct ctcaggcaaa
    17461 tacgcggaca aaccggcctc acaccgtcca ccccgttttc cgaacaactg cgttgcgccg
    17521 tttcaggcga aagctacatc agcccgtcgt ggcacggact gcactgctac ggcgcgagtt
    17581 ttattcccaa cagcagccat accggatgga acgaagccga agaagcctca aaccgccaag
    17641 cattggcaca ccttaacccc gccctttccg aatcattgtt tgccgccaac ccaaaccccc
    17701 aaaaacacca agggcacgcc gccatacgct gcgacagccc cgaccacctt cccctagtcg
    17761 gcgcactcgg cgacattgcc gccatgcggc agacctacac caaactcgcg ctggacaaaa
    17821 actaccgcat cgacacccca tgcccatacc tgcctaatgc ctacgtcaac accgcgcacg
    17881 gcacccgcgg actcgccacc gcccccatct gcgccgccgc cattgcagcc caaatcctag
    17941 gcttgcccca tcccttttca caacgcctgc gccacgccct acaccccaac cgcaccatca
    18001 tccgcgccat cgtcagaagg aaggatctaa ccccttaagc ctttgccgca tgccgtcccg
    18061 accacagaaa atcatattca aataaacata ccaatcctga cggtaaaata tcgaaaacac
    18121 ccataacgtt ttcttcccaa aataaggagt aaggaatgcc taacaaattg cctttgctgt
    18181 ccaagatgaa tgttccgtaa cattcgaaga cttccttaac cctgccagcc gtttcggttt
    18241 ctgtaccccc tgttagataa ggaaggaatg aaaaagccct gttgattgta tgaagtaaag
    18301 ggcgttaatt tttgttaatc ttcccttctc aggaactcaa tatataagga tgttaa
//
LOCUS       DAXISH010000043        18182 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.043, whole genome shotgun sequence.
ACCESSION   DAXISH010000043 DAXISH010000000
VERSION     DAXISH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 18182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18182
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.043"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..573
                     /locus_tag="ACFOV4_001437"
     CDS             <1..573
                     /locus_tag="ACFOV4_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224706.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
                     /protein_id="HFC7619427.1"
                     /translation="DLGKLSPEAQLAAASLLQDSAFAVKDGINSARQWADAHPNITAT
                     AQTALAVAEAAGTVWRGKKVELNPTKWDWVKNNGYKTPAARPMQTLDGEMAGGNKPVV
                     KSIRPTTRDELRQALQEQGFRRTGSDEAQYETWKGPDGVKIDIRPNGEVIRTQRVPRT
                     DGVQGKYPQRQNYEGNPLPNNRHHSGYFIK"
     gene            570..887
                     /locus_tag="ACFOV4_001438"
     CDS             570..887
                     /locus_tag="ACFOV4_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619428.1"
                     /translation="MKKNIFHNVSLYEIIFSDNGNTLTLSFTDTIEGNYFGYIKCSNI
                     LNFKLDTNNFVDYEDKEDSLFPLFIPEIELYKYQFYSEIIIDVGIIIKISAETINFEP
                     LGK"
     gene            957..1250
                     /locus_tag="ACFOV4_001439"
                     /pseudo
     CDS             957..1250
                     /locus_tag="ACFOV4_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225727.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI.; incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
     gene            1245..1697
                     /locus_tag="ACFOV4_001440"
     CDS             1245..1697
                     /locus_tag="ACFOV4_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619429.1"
                     /translation="MQTKALGTVDEIGDTVQQVGKQASGQKTSGGNPAIDSDPYSPSS
                     VAARIETGKVRSDLQIKDILSNTTQRSKTKGPAVQYDKVGDYNDALNDFNSLNVRNVQ
                     TRPNGTITGNLPDRRAVNARNDSSGGEPTLEITISNNRKIKIRYGNTR"
     gene            1701..2102
                     /locus_tag="ACFOV4_001441"
     CDS             1701..2102
                     /locus_tag="ACFOV4_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619430.1"
                     /translation="MKLKSLDFPTGYFYFDNAAINSDKVEVIAVGYRNTDKTIKIFIE
                     DVIHFRVVDESYFIDTFMDLISEDADRALLHENGGQSFFELLDECYAEWILKESYFPL
                     NREFFKYYIFMFEQTFIEIIGSSATYSIIEG"
     gene            2261..2603
                     /locus_tag="ACFOV4_001442"
                     /pseudo
     CDS             2261..2603
                     /locus_tag="ACFOV4_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688154.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2637..2738
                     /locus_tag="ACFOV4_001443"
     CDS             2637..2738
                     /locus_tag="ACFOV4_001443"
                     /inference="COORDINATES: protein motif:HMM:NF018014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619431.1"
                     /translation="MDDIRGIIQGAVNPLIYKVSKQKIIYNKLISGT"
     gene            2743..3099
                     /locus_tag="ACFOV4_001444"
     CDS             2743..3099
                     /locus_tag="ACFOV4_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMP12 family DNA mimic protein"
                     /protein_id="HFC7619432.1"
                     /translation="MNEHNLLIFCLKDNVSISEYTEMIDWAYKNIQSETVVEITESQI
                     IEYQNRGLWRLVSEITDNWLFGPSEGDWLIDKESILAVKEKLQNSDFSTEPLVKNIIH
                     VLEYAIKNKKTVIFHF"
     gene            3147..3275
                     /locus_tag="ACFOV4_001445"
     CDS             3147..3275
                     /locus_tag="ACFOV4_001445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619433.1"
                     /translation="MPQTWGEAIQFRIKKQIENELAPPNWSTQFPNGSIYDPKVTK"
     gene            3272..3646
                     /locus_tag="ACFOV4_001446"
                     /pseudo
     CDS             3272..3646
                     /locus_tag="ACFOV4_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709227.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3684..3946)
                     /locus_tag="ACFOV4_001447"
                     /pseudo
     CDS             complement(3684..3946)
                     /locus_tag="ACFOV4_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557955.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4026..4553)
                     /locus_tag="ACFOV4_001448"
                     /pseudo
     CDS             complement(4026..4553)
                     /locus_tag="ACFOV4_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003684692.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS481 family transposase"
     gene            complement(4602..5588)
                     /locus_tag="ACFOV4_001449"
     CDS             complement(4602..5588)
                     /locus_tag="ACFOV4_001449"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HFC7619434.1"
                     /translation="MQYRIRRENEAPEAKNAGETLWERDIMREVLLSAYQDRRRERMW
                     KNIWRAVSTLILVALIAGIFRKDEAALQLAGNTPHTAVVNLYGEIGNGVEDQVKKLKD
                     GMEAAYKNPQAKAIVIRANSPGGSPVVSNTAFEEIRRLKAQHPGIPVYLVAEDMCASG
                     CYYIAAAADKIYADPSSIVGSIGVIGSSFDATGLMEKIGVKRRVKIAGSNKGMGDPFS
                     PETPEQSKIWEEMLTGIHGEFIKAVKTGRGGRLKFRQYPDVFSGRVYTGADALKVGLV
                     DGLGNIYSVARDVVKAPDVVDYTPKDDFGRILGRRFGAELKASVREALQAVR"
     gene            complement(5628..6428)
                     /locus_tag="ACFOV4_001450"
     CDS             complement(5628..6428)
                     /locus_tag="ACFOV4_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003705157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFC7619435.1"
                     /translation="MNAFNLIIIGDEILHGSRQDKHFAFFKSLLESKGLKLNQVQYLP
                     DEPDLLVRQLRRSFSDGIPTFVTGGIGATPDDHTRQAAAAALDLPVVRHPEAAKFIEG
                     ITQKRGEPLDSPEHAQRLKMADFPEGAELVPNPFNNIAGFSIREHYFFPGFPVMAHPM
                     AEWVLNTYYADRFNQTERGSRSVYVFEQPESRITPLMEHIEQTYPGVRSYSLPSVGWT
                     HSDGTQVKPHIEFGIKAEGEAVNLLDAAWAEVLHSLDGLGAELKNRVN"
     gene            6553..7896
                     /gene="argG"
                     /locus_tag="ACFOV4_001451"
     CDS             6553..7896
                     /gene="argG"
                     /locus_tag="ACFOV4_001451"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HFC7619436.1"
                     /translation="MNQNHTILQNLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAY
                     TANLGQPDEDDYNAIPKKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAY
                     FNTTPLGRAVTGTMLVSAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPW
                     LDQQFIDELGGRHEMSEFLIANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIK
                     IVKPIMGVAFWDENVEIEPEEVSVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGL
                     GMSDQIENRIIEAKSRGIYEAPGMALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLL
                     YQGRWFDSQALMLRETAQRWVAKAVTGEVTLELRRGNDYSILNTESPNLTYQPERLSM
                     EKVEGAAFTPLDRIGQLTMRNLDITDTRAKLGIYSQSGLLSLGEGSVLPQLGNKK"
     gene            7971..8099
                     /locus_tag="ACFOV4_001452"
                     /pseudo
     CDS             7971..8099
                     /locus_tag="ACFOV4_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242091.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
     gene            8244..8372
                     /locus_tag="ACFOV4_001453"
                     /pseudo
     CDS             8244..8372
                     /locus_tag="ACFOV4_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242091.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
     gene            8365..8580
                     /locus_tag="ACFOV4_001454"
     CDS             8365..8580
                     /locus_tag="ACFOV4_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619437.1"
                     /translation="MFKLGVYACLGLFAGWVLLLIVQLWFSFLEAELFFKITLTMAGL
                     FVIILAALLVFGQYFSEKKMKDDGFIN"
     gene            complement(8657..9937)
                     /locus_tag="ACFOV4_001455"
     CDS             complement(8657..9937)
                     /locus_tag="ACFOV4_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="HFC7619438.1"
                     /translation="MFERSVIAMACIFALSACGGGGGGSPDVKSADTPSKPAAPVVAE
                     KETEVKEDAPQAGSQGQGAPSTQGSQDMAAVSAENTGNGGAATTDKPKNEDEGPQNDM
                     PQNAGNTAAQGTNQAENNQVGGSQNPAPSSNPNATNGGNFGRVDLANGVLIDGPSQNI
                     TLTHCKSDSCNGDNLLSEEAPSKSEFEQLSDEDKIKKYKKDGEKFTGLVADRLQMKGT
                     NQYIIFYKPKTTSSARFRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNI
                     FAPEGNYRYLTYGAEKLSGGSYALSVQGEPAKGEMLAGTAVYNGEVLHFHTENGRSYP
                     TKGRFAAKVDFGSKSVDGIIDSGDDLHMGKQKFKAAIDGNGFKGTWTENGGGDVSGRF
                     YGPAGEEVAGKYSYRPTDAEKGGFGVFAGKKEQD"
     gene            complement(10049..11278)
                     /gene="sstT"
                     /locus_tag="ACFOV4_001456"
     CDS             complement(10049..11278)
                     /gene="sstT"
                     /locus_tag="ACFOV4_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFC7619439.1"
                     /translation="MAFGKSLFHAIGRVSLVRQIAAGLALGIVIGSVSPQLGLAAGLF
                     GSLFVGALKAVAPVLVFILVAATIAQHQKGNKAHIRPIIVLYLIGTFSAALTAVIAGM
                     VFPTHIVLAGAGDVSAAPPSGIVEVLKSLLMNLVANPINAIANANYIGILAWALVLGA
                     ALRNHGSDVTRQVVADLAEAVSTVVKWIIRFAPLGIFGLVSSTIAETGFGALAGYAKL
                     LAVLLGCMAFIALVVNPAIVWWKIRRNPYPLVFTCLRESGVYAFFTRSSAANIPVNMA
                     LAKKLGLHEDTYSISIPLGATVNMGGAAITITVLAMAAAHTQGIQVDFATALLLSLVA
                     TVSACGASGVAGGSLLLIPLACSLFGISNDVAMQVVAVGFIIGVIQDSAETALNSSTD
                     VLFTAAADLGRQRNRAE"
     gene            11807..13654
                     /locus_tag="ACFOV4_001457"
     CDS             11807..13654
                     /locus_tag="ACFOV4_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex family protein"
                     /protein_id="HFC7619440.1"
                     /translation="MHDTRTMMIKPTALLLPALFFFPHAYAPAADLSENKAAGFALFK
                     NKSPDTESVKLKPKFPVRIDTQDSEIKDMVEEHLPLITQQQEEVLDKEQTGFLAEEAP
                     DNVKTMLRSKGYFSSKVSLTEKDGAYTVHITPGPRTKIANVGVAILGDILSDGNLAEY
                     YRNALENWQQPVGSDFDQDSWENSKTSVLGAVTRKGYPLAKLGNTRAAVNPDTATVDL
                     NVVVDSGRPIAFGDFEITGTQRYPEQIVSGLARFQPGTPYDLDLLLDFQQALEQNGHY
                     SGASVQADFDRLQGDRVPVKVSVTEVKRHKLETGIRLDSEYGLGGKIAYDYYNLFNKG
                     YIGSVVWDMDKYETTLAAGISQPRNYRGNYWTSNVSYNRSTTQNLEKRAFSGGIWYVR
                     DRAGIDARLGAEFLAEGRKIPGSDVDLGNSHATMLTASWKRQLLNNVLHPENGHYLDG
                     KIGTTLGTFLSSTALIRTSARAGYFFTPENKKLGTFIIRGQAGYTVARDNADVPSGLM
                     FRSGGASSVRGYELDSIGLAGPNGSVLPERALLTGSLEYQLPFTRTLSGAVFHDMGDA
                     AANFKRMELKHGSGLGVRWFSPLAPFSFDIAYGHSDKKIRWHISLGTRF"
     gene            13709..17878
                     /locus_tag="ACFOV4_001458"
     CDS             13709..17878
                     /locus_tag="ACFOV4_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translocation/assembly module TamB
                     domain-containing protein"
                     /protein_id="HFC7619441.1"
                     /translation="MTDTAPTDTDPTENGTRKMPSEHRPTPPAKKRRPLLKLSAALLS
                     VLILAVCFLGWLAGTEAGLRFGLYQIPSWFGVNISSQNLKGTLLDGFDGDNWSIETEG
                     ADLKISRFRFAWKPSELMRRSLHITEISAGDIAIVTKPTPPKEERPPLSLPDSIDLPA
                     AVYLDRFETGKISMGKAFDKQTVYLERLDASYRYDRKGHRLDLKAADTPWSSSSGSAS
                     VGLKKPFALDTAIYTKGGLEGKTIHSTARLSGSLKDVRAELAIDGGNIRLSGKSVIHP
                     FAESLDKTLEEVLVKGFNINPAAFVPSLPDAGLNFDLTAIPSFSDGIALEGSLDLENT
                     KAGFADCNGIPVRQVLGGFVIRQDGTVHIGNTSAALLGRGGIRLSGKIDTEKDILDLN
                     IGINSVGAEDVLQTAFKGRLDGSIGIGGTTASPKISWQLGIGTARTDGSLAIASDPAN
                     GQRKLVLDTVNIAAGQGSLTAQGYLELFKDRLLKLDIRSRAFDPSRINPQLPAGNING
                     SINLAGELAKEKFTGKMRFLPGTFNGVPIAGSADIVYESRHLPRAAVDLRLGRNIIKT
                     DGGFGKKGDRLNLNITAPDLSRFGFGLAGSLNVRGHLSGDLDGGIRTFETDLSGAARN
                     LHIGKAADIRSLDFTLKGSPDTSRPIRADIKGSRLSLSGGAAVVDTADLMLDGTGVQH
                     RIRTHAAMTLDGKPFKFDLDASGGINRELTRWKGSIGILDIGGAFNLKLQNRMTLEAG
                     AERVAASAANWQAMGGSLNLQHFSWDRKTGISAKGGARGLHIAELHNFFKPPFEHNLV
                     LNGDWDVAYGRNARGYLNISRQSGDAVLPGGQALGLNAFSLKTRFQNDRIGILLDGGA
                     HFGRINADLDIGNAFGGNMANAPLGGRITASLPDLGALKPFLPAAAQNITGSLNAAAQ
                     IGGRVGSPSVNVAVNGSSNYGKINGNITVGQSRSFDTAPLGGRLNLTVADAEVFRNFL
                     PVGQTVKGSLNAAVTLGGSIADPHLGGSINGDKLYYRNQTQGIILDNGSLRSHIAGRK
                     WVIDSLKFRHEGTAELSGTVGMENSGPDVDIGAVFDKYRILSRPNRRLTVSGNTRLRY
                     SPQKGISVTGMIKTDQGLFGSQKSSMPSVGDDVVVLGEVKKEAAAPLPVNMNLTLDLN
                     DGIRFAGYGADVTIGGKLTLTAQSGGSVRGVGTVRVIKGRYKAYGQDLDITKGTVSFV
                     GPLNDPNLNIRAERRLSPVGAGVEILGSLNSPRITLTANEPMSEKDKLSWLILNRAGS
                     GSSGDNAALSAAAGALLAGQINDRIGLVDDLGFTRKRSRNAQTGELNPAEQVLTVGKQ
                     LTGKLYIGYEYSISSAEQSVKLIYRLTRAIQAVARIGSRSSGGELTYTIRFDRFSGSD
                     KKDSAGNGKGK"
BASE COUNT         4707 a         4844 c         4404 g         4227 t
ORIGIN      
        1 gatttaggaa aattaagtcc ggaagcacaa cttgctgccg cgagcctatt acaggacagt
       61 gcttttgcgg taaaagacgg catcaattcc gccagacaat gggctgatgc ccatccgaac
      121 attacagcta ctgcccaaac tgcccttgcc gtagcagagg ccgcaggtac ggtttggaga
      181 ggtaaaaaag tagaacttaa cccgactaaa tgggattggg ttaaaaataa cggctataaa
      241 acacctgctg cccgccctat gcagacgttg gacggtgaga tggcaggagg aaacaagcca
      301 gttgttaaat ctatcagacc aactacgcga gatgaattac gtcaagcatt gcaagaacaa
      361 ggttttagac gtactggttc agatgaggct caatatgaaa catggaaagg tcctgatggc
      421 gtgaaaatag atattcgtcc aaatggagag gttataagaa cccaaagagt gccgcgaacc
      481 gatggtgtac agggaaaata tccgcaacga caaaattatg aaggcaatcc attgccaaat
      541 aatcgtcatc attctggata ttttatcaaa tgaaaaaaaa tatttttcac aatgtaagcc
      601 tttatgaaat aatcttttcc gataatggaa atacccttac attatctttt acagatacaa
      661 ttgaaggtaa ttatttcgga tatatcaaat gcagtaatat tttgaatttt aaattagata
      721 caaataattt cgtagattat gaggataagg aagatagctt gtttcccttg tttatacccg
      781 aaatagagct atataaatac caattttata gtgaaattat tattgatgta gggattatta
      841 taaaaatatc tgctgaaaca attaattttg agccactggg aaaatagtaa ctgctttccc
      901 agcagccgta gcaactgtat ttttacccga cggggtaaaa atacagttgc tacatctctg
      961 cgcagcagac tctacaaggt attaataatt taggaaaatt aagcccggaa gcacaacttg
     1021 ctgccgcgag catattacag gacagtgctt ttgcggtaaa agacggcatc aattccgcca
     1081 gacaatgggc tgatgcccat ccgaatataa cagcaacagc ccaaactgcc cttgccgtag
     1141 cagaggccgc aggtacggtt tggagaggta aaaaagtaga acttaacccg accaaatggg
     1201 attgggttaa aaataccggc tataaaaaac ctgctgttcg ccatatgcag actaaggcgt
     1261 taggtacggt agatgaaatt ggcgatacag tacagcaggt tgggaaacag gctagcggac
     1321 aaaaaaccag cggtggtaat cctgcgattg atagcgaccc ctatagcccg agtagtgtgg
     1381 cagctcgcat agaaaccggt aaggtgcgca gtgatttaca aatcaaagac attttgagca
     1441 atactactca aaggagtaaa acaaaaggtc ccgctgttca gtatgataaa gtgggggatt
     1501 acaatgacgc actaaatgat tttaatagtc tgaatgttcg aaatgtacaa acacgtccta
     1561 atggaacgat aacgggcaat ttacctgata ggcgtgcggt taatgctcgt aatgatagta
     1621 gtggtggaga accaacactt gaaataacaa ttagtaataa ccgaaaaata aaaatcagat
     1681 atggaaatac acgataaatt atgaaattaa aaagcttaga tttcccaact ggctatttct
     1741 attttgataa tgcagcaata aactctgata aagtagaagt tatagcagtt ggttatagaa
     1801 atacggataa aaccataaaa atttttattg aagatgttat tcattttagg gttgttgatg
     1861 aatcgtattt tatagatact tttatggatt taatttcgga agatgcagat agagctttgc
     1921 ttcatgaaaa tggtggtcaa tctttttttg aacttcttga tgagtgttat gcggaatgga
     1981 tattgaaaga aagttatttt cctttgaata gagaattctt taaatactat atttttatgt
     2041 ttgagcaaac attcatagaa ataattggtt ctagtgcaac gtattcaatt attgagggct
     2101 agcgtaagat gagtaataag ttgcctatct ttctttcagg cagcctgaaa ataaaactac
     2161 ccaagttgat ggtgtacctg tatcagtgaa gggaaatttt gttgatggta aatttcgcat
     2221 tggtacggca acaatgaaat cattttaaat tgagctagaa atgaacctag aaaattatga
     2281 aaacatttta ataaaattac ttttttatca taacaactta gtaaatgaat attcttattt
     2341 tattgaaaat aaaaatttat ttaaaatagt atctcgaact aaaacgagta agggcttttt
     2401 ttcactatag aaaaaccatt aaattttcta agcaaaaaaa cttattttga gtttaatttt
     2461 aaatatttac actcagggaa agaacgcttt ggttcgttta tgtgctggat aaatactaat
     2521 ttaatggaat ttgagggggt ttttttaacg acctgctccc tgataatatg ataataaata
     2581 acttttttga aataaatgat taacgataca ccaataaaaa ttggtggggt aaccgtatgg
     2641 atgatattcg cggcatcatc caaggtgcgg ttaatccttt aatttacaag gtaagcaagc
     2701 aaaagattat ttacaacaaa ctcatatcag gaacttagac aaatgaatga acacaacctg
     2761 ttaattttct gtttaaaaga caatgtttca attagtgaat atactgaaat gattgattgg
     2821 gcttataaaa atattcaatc tgaaacagtt gtagaaatta cggaaagtca aattattgaa
     2881 tatcaaaatc gtggattatg gagacttgtt tctgaaatta ccgataattg gttatttgga
     2941 ccaagtgagg gggattggct aatagataag gaaagtattt tggctgtaaa agaaaaatta
     3001 caaaattcag atttttctac agagccctta gtgaaaaata ttattcatgt acttgaatat
     3061 gctataaaaa ataaaaaaac agtaattttt catttttgag actaatccaa tttttagtaa
     3121 tattgatgca gagcaagcag cattagatgc cgcaaacatg gggagaagct attcaattta
     3181 gaattaaaaa acaaattgaa aatgaactag caccaccaaa ttggtctacc cagtttccta
     3241 atggtagtat ttatgatcct aaggtaacga aatgattatt caaaatgaat ttaatttata
     3301 tcctagtaat atgcttcctg aaaggttttg ttatcctgaa aagtatgttc gtatctctaa
     3361 cgatacatct ttaatacctt atattcagcc acataatttt cactggtagt ttgagaatta
     3421 tggaacagaa ggggcagaag tagcttatat atttagaaat tctatcctgc ctgatttaaa
     3481 tcttatccca ttcgctagta atggagaatg ggaagcttat tttgatggta atgatgtaac
     3541 aggaaattct agggttattg tcattaattt agataatata gaaaaccatg aattttttaa
     3601 tagttttgaa gattggcttg aattagcaat taaggatact tggtaagcag ctatctataa
     3661 agagatgagg ctgccttgga caactaggat aaactcgatt ttactaattg ttttaaaatg
     3721 gaacaagaac ttttatttca ctgttgttaa aacgccattc gcactccttt aaatacagct
     3781 caaaatgcgc tttgggaatg ccgttaaact tgcgtaaatg acgttttgct tgattccaaa
     3841 agttctcagt tccattaata tggttttgtc gttcggcaaa atgtgtgctg tgattgatac
     3901 ggaaatggct aaattcgccc gcatccaata catcatagcc acgataacaa aatgagttta
     3961 ttttgtttat accgtcttag acgactttct ctcataggga taattctaac ttaatttgaa
     4021 tttccctagt gatctagggc agcccctaaa ttaataaagc agcacaactc cttttgccga
     4081 tgttccggac tgtcaaacga ctgttcctca tgccacatct ccatcaaggt acggataacc
     4141 cgctccgcct taccgttggt ctgcggacaa gcaaatcggg caagcctcca accaatccca
     4201 ttattataac aagctgcacc gaaagcatgt tggacggctc tttatattac ctatcattgt
     4261 cagagtaaac gtactcaatc aggtacaagc aggggtcagc cagatgttcg gtcagaaact
     4321 tggcagcact gtctgcggtt ttgtccggca aaatggcaga gtataaaaat cgtcaatagc
     4381 gacaaacagg taatctcgtt tatcggcggc cttctgtcct ttgagcaaca acaaccgatc
     4441 ggtatcagga tgaacaaaac ctcccgggac aacctgcctt ttacggcttt aagtgcacgg
     4501 taaatagtga cgcggctgac ttagtggcag catactgggg aggtgagtgt ttttgtgtat
     4561 atttttattt tggtattccc ttagaaatac tgtaaacaac gctaccggac ggcctgcagg
     4621 gcttcgcgca cgcttgcttt gagttctgcg ccgaagcgtc tgcccaagat tctgccgaaa
     4681 tcgtccttcg gagtgtaatc caccacatcg ggggctttga ccacgtctcg cgccacgctg
     4741 taaatattgc cgagtccgtc caccagcccg actttcagcg catccgcgcc tgtgtacacg
     4801 cgaccgctga acacgtcggg atattgtcgg aatttgaggc ggccgccgcg tccggttttg
     4861 acggctttga tgaactcacc gtgtatgccg gtcagcattt cttcccagat ttttgactgt
     4921 tcgggcgttt cgggcgaaaa cggatcgccc atgcctttgt tgctgcctgc aattttaacc
     4981 ctgcgtttca cgccgatttt ttccatcagg ccggtcgcgt cgaaactgct gccgataacg
     5041 ccgatgctgc cgacgatgct ggacgggtcg gcatagattt tgtccgccgc cgccgcgatg
     5101 tagtagcagc cggacgcgca catatcttcc gccacgagat aaacgggaat gccggggtgc
     5161 tgcgccttca gacggcgtat ttcttcaaaa gcggtgttgg agacgacggg cgaaccgccg
     5221 gggctgttgg cgcggatgac gatggctttt gcctgcgggt ttttgtaggc ggcctccata
     5281 ccgtctttga gttttttgac ctggtcttct acaccgttgc cgatttcgcc gtacaggttg
     5341 acgactgcgg tatgcggcgt gttgcccgcc aactgcaatg cggcttcgtc ttttcggaaa
     5401 atgcctgcaa tcagggcaac cagaatcagg gtgctgacgg cgcgccagat gtttttccac
     5461 atccgctccc tgcgcctgtc ctgataggcg gacagcagca cttcgcgcat gatgtcgcgc
     5521 tcccataagg tttcccccgc attttttgct tcgggtgctt cgttttctct tctgattcgg
     5581 tattgcatgg ttttccttaa atattgtccg atttgggcaa acggttttca gtttacccga
     5641 tttttcagct ctgctcccaa tccgtccaag ctgtgcaaca cttccgccca cgccgcgtcc
     5701 aaaaggttga cggcttctcc ttcggctttg atgccgaact caatgtgcgg tttgacctgc
     5761 gtgccgtctg aatgcgtcca accgacgctg ggcaggctgt acgaacgcac accgggataa
     5821 gtttgctcga tatgctccat aagcggcgta atgcgcgatt cgggctgctc aaacacatac
     5881 acgctgcggc tgccgcgttc ggtttggttg aagcggtcgg cgtaataagt attcaaaacc
     5941 cattccgcca tcgggtgcgc catcacagga aagccgggga agaaataatg ctcgcggatg
     6001 gaaaatccgg cgatgttgtt gaacgggttg ggcacaagct ctgcgccctc ggggaaatcc
     6061 gccattttca ggcgttgggc gtgttccggc gaatcaagcg gctcgccgcg tttctgggtt
     6121 atgccttcga taaacttggc ggcttcagga tggcggacga caggcaaatc caaagcagca
     6181 gccgcggctt ggcgcgtgtg gtcgtcgggc gtggcgccga tgccgccggt aacaaacgtc
     6241 ggtatgccgt ctgaaaagct gcggcgcagt tgcctgacca gtaaatcggg ttcgtcgggt
     6301 agatattgca cctgattgag cttcagccct ttggattcga gcagggattt gaaaaaggcg
     6361 aaatgcttgt cttggcggct gccgtgcagg atttcgtcgc cgatgatgat gaggttgaac
     6421 gcgttcataa tgttttcggt tttaaatacc gcctgaaacg gcggaatacc cgttcagacg
     6481 gcatgatggc tgacaatatt tcctatttat aagataatgg ctttgatttt tcaagctacc
     6541 gaggattttt tcatgaacca aaaccatact attttacaaa atctccccgt cggtcagaaa
     6601 gtcggcatcg ccttctccgg cggacttgat acctccgccg cgctgttgtg gatgaaactc
     6661 aaaggcgcgc tgccttatgc ctacactgcc aacctcggcc agcccgacga agacgattac
     6721 aacgccattc ccaaaaaagc gatggaatac ggcgcggaaa acgcccgctt aatcgactgc
     6781 cgcgcgcagt tggcacatga aggcatcgcc gccatccaat gcggcgcgtt ccacgtttcc
     6841 accggcggca tcgcctattt caacaccacg cctctgggcc gcgccgtgac cggcaccatg
     6901 ctcgtttccg caatgaaaga agacgatgtg aatatttggg gcgacggcag cacctacaaa
     6961 ggcaacgaca tcgagcgttt ctaccgctac ggtttgctca ccaatcccgc gctgaaaatc
     7021 tacaaaccct ggctcgatca gcaatttatc gacgaactcg gcggccgtca cgaaatgagc
     7081 gaatttctga ttgccaacgg cttcaactac aaaatgtcgg tggaaaaagc ctactccacc
     7141 gattccaata tgttgggtgc cacccacgaa gccaaagact tggaattttt gaactcgggc
     7201 atcaaaatcg tcaaacccat tatgggcgtt gccttttggg acgaaaacgt cgaaatcgaa
     7261 cccgaagaag tcagcgtacg ctttgaagaa ggcgtgccgg ttgcactgaa cggcaaagaa
     7321 tacgctgatc ccgtcgaact cttcctcgaa gccaaccgca tcggcggccg ccacggtctg
     7381 ggtatgagcg accaaatcga aaaccgcatc atcgaagcca aatcgcgcgg catctacgaa
     7441 gccccgggaa tggcgttgtt ccacatcgcc tacgaacgct tggtaaccgg catccacaac
     7501 gaggacacca tcgaacaata ccgcatcaac ggcctgcgcc tcggacgttt gctctaccaa
     7561 ggccgctggt tcgacagcca agccctgatg ttgcgcgaaa ccgcccaacg ctgggtcgct
     7621 aaagccgtta ccggcgaagt taccctcgaa ctgcggcgcg gcaacgacta ctcgattctg
     7681 aacaccgaat cgcccaatct gacctaccaa cccgaacgcc tgagtatgga aaaagtcgaa
     7741 ggtgcggcgt ttaccccgct agaccgcatc ggacagctca cgatgcgcaa ccttgacatc
     7801 accgacaccc gcgccaaact gggtatctac tcgcaaagcg gtttgctctc gctgggcgaa
     7861 ggctcggtat tgccgcagtt gggcaataag aaataaggtt tgctgttttg catcattagc
     7921 aacttaaggg gtcgtctgaa aagatgatcc cttatgttaa aaggaatcct atgaaagaat
     7981 acaaagtcgt catttatcag gaaagcctgt tgtccagcct gtttttcggc gcgacaaagg
     8041 tcaaccccgt caatttcagc gcgttcctca acaaacaaac ccccgaaggc tggcgggtcg
     8101 agacctttgc aataacatag gttactaaaa ttttatgctc aatctcattt tcaaaatgca
     8161 aaacttttct gatttttcct actttttgct caatattagg aaggttttag gcaattgaaa
     8221 attttttggc gcatttttat gcgtcaaatt tcgttaacag actatttttg caaaggtctc
     8281 gggtcgtaac gatggaaaaa gatttgcgcc gtatgctgct gtttttcaaa cgcgaggcct
     8341 acgtcgtcat tttggagcgg gaccgtgttt aagctcggcg tttatgcctg tctcggactg
     8401 tttgccggct gggtgctgct gctgattgtg caactctggt tttcttttct cgaagcggaa
     8461 ttgttcttca aaatcacact gactatggcg gggctgtttg tcatcatcct cgccgccctg
     8521 ctggtattcg gccagtattt ttccgaaaag aaaatgaaag acgacgggtt tatcaactga
     8581 tgcggacttg aaccggactc gccgccccaa acatcacaat gccgtctgaa cgcccccgct
     8641 tcagacggca tcaacatcaa tcctgctctt ttttgccggc aaacacgccg aatccgccct
     8701 tttccgcatc tgtcgggcga tagctgtatt ttcccgccac ttcctcgccg gccgggccgt
     8761 aaaaccttcc ggaaacatcc ccgccgccat tttccgtcca agtcccctta aagccgtttc
     8821 catcgatggc ggctttgaat ttttgcttac ccatatgcaa atcatcgccg ctgtcgataa
     8881 tgccgtccac agatttgctg ccgaaatcga cttttgcggc aaacctgcct ttggtcgggt
     8941 acgaacgtcc gttttccgta tggaaatgca gcacttcgcc gttgtacacg gccgtgccag
     9001 caagcatttc gccttttgcc ggttcgcctt gcacactgag ggcatacgat ccgccggaca
     9061 atttttctgc cccgtaagtc agataccggt aattcccttc gggcgcgaag atattgccgg
     9121 aatgccccgt caggctgacc gcttccccat cgacaatcag cgtatccgcc tgattgacgg
     9181 ggatcagcgg catctcagcc ggaagcgacc tcctagaccg tgcagaacgc ctgaatcgcg
     9241 cagatgaagt ggttttaggt ttgtaaaaaa taatatattg attggttcct ttcatctgta
     9301 acctatcagc aaccaaaccg gtaaactttt ctccatcttt tttatatttc ttaattttgt
     9361 cttcatcact taattgttca aattctgatt ttgacggtgc ttcttcgctt aatagattat
     9421 caccattaca agaatcgctt ttacaatggg tcaacgttat attttgcgac ggtccgtcaa
     9481 tcaaaacacc gttagccaaa tcaacccttc caaaattgcc accattcgtg gcattaggat
     9541 tgcttgaagg ggcaggattt tgagagccgc cgacttgatt gttttcggct tgatttgtac
     9601 cttgggcagc cgtattgccg gcattttgcg gcatatcatt ttgcggtccc tcgtcttcat
     9661 ttttgggttt gtccgttgtt gccgcaccgc cattgcctgt attttctgcc gaaactgccg
     9721 ccatatcttg gctgccttgt gtggatggcg cgccctgtcc ttgagaacct gcctgtggcg
     9781 catcttcttt tacctctgtc tctttttcag caacaacagg agcggccggt tttgacggtg
     9841 tgtccgccga cttaacatcg ggcgatccgc caccgccgcc cccacaggct gaaagggcaa
     9901 aaatacaagc cattgcaatc acactgcgtt caaacatcat catctccttc atattcaagg
     9961 cagccggtat tgtttccgcc atatgcccat aaaattgtaa aaatatgccg tctgaacgcc
    10021 aaatgggctt cagacggcat agcttggttt attccgcccg gtttctctgt cggcccaaat
    10081 cggcagcagc ggtaaacaaa acgtcggttg aagaattcaa cgccgtttcc gccgaatcct
    10141 gaatcacgcc gatgataaag ccgacggcaa ccacctgcat ggcgacatcg ttgctgatgc
    10201 cgaacaggct gcacgccagc ggaatcagca gcagcgaacc gcccgccacg ccggacgcgc
    10261 cgcacgcgct gaccgtcgcc accaggctca acagcagcgc ggtggcaaaa tcaacctgta
    10321 tgccttgggt gtgcgccgcc gccatagcca aaacggtaat cgtaatcgcc gcgccgccca
    10381 tattgacggt cgcccccaac gggatggaaa tcgaataagt gtcttcgtgc agccccagtt
    10441 ttttcgccaa agccatattc acggggatat tggcggcgga agaacgggta aagaaggcat
    10501 acacgccgct ttcgcgcagg caggtaaaca ccagcggata agggttgcgg cggattttcc
    10561 accacacgat ggcgggattg accactagcg cgataaacgc catacagccc aacagcaccg
    10621 caagcagctt cgcataaccc gccagcgcgc cgaaacccgt ctccgcgatt gtggacgaca
    10681 ccagcccgaa aatgcccaaa ggggcaaaac ggataatcca tttcacgacg gtggaaaccg
    10741 cttccgccaa atcggcaacg acctgccgcg taacgtccga accgtgattc cgcaacgccg
    10801 cgcccaaaac caaagcccaa gccagaatgc cgatatagtt ggcattggca atcgcgttaa
    10861 tcgggttggc gaccaggttc atcagcagcg atttcaacac ttccacaatg ccggaaggcg
    10921 gcgcggcgga cacatcgccc gcgcccgcca aaacaatgtg cgtcgggaaa accataccgg
    10981 cgatgacggc ggtcagggct gcggaaaacg taccgatgag gtaaaggacg ataatcggcc
    11041 tgatatgcgc cttgttgcct ttttggtgct gcgcgattgt ggccgccacc aaaataaata
    11101 ccaaaaccgg cgcgaccgct ttgagcgcgc cgacaaacag gctgccgaac aagcctgccg
    11161 ccaagcccag ttgcggggaa accgaaccga ttacgatgcc caacgccaaa ccggcggcaa
    11221 tctgcctgac caggctgacg cggccgatcg catgaaataa ggatttgccg aacgccataa
    11281 ttcttcctta tgttgtgata tgttaaaaaa tgttgtattt taaaagaaaa ctcattctct
    11341 gtgttttttt atttttcggc tgtgttttat agtggattaa caaaaatcag gacaaggcga
    11401 cgaagccgca gacagtacaa atagtacgga accgattcac ttggtgcttg agcaccttag
    11461 agaatcgttc tctttcagct aaggcgaggc aacgccgtac tggtttttgt taatccacta
    11521 tgaaggttgc gttgatttgc cctatgcagt gccggacagg ctttgcttga tcattcggcg
    11581 caacggttta atttattgaa cgaaaataaa tttatttaat cctgcctatt ttccggcact
    11641 attccgaaac gcagcctgtt ttccatatgc ggattagaaa caaaatacct taaaacaagc
    11701 agatacattt ccggcgggcc gcaacctccg aaataccggc ggcagtatgc cgtctgaagc
    11761 gtcccgcccc gtccgaacag tgttaaaatc gaaatccgcc acaccgatgc acgacacccg
    11821 taccatgatg atcaaaccga ccgccctgct cctgccggct ttatttttct ttccgcacgc
    11881 atacgcgcct gccgccgacc tttccgaaaa caaggcggcg ggtttcgcat tgttcaaaaa
    11941 caaaagcccc gacaccgaat cagttaaatt aaaacccaaa ttccccgtcc gcatcgacac
    12001 gcaggatagt gaaatcaaag atatggtcga agaacacctg ccgctcatca cgcagcagca
    12061 ggaagaagta ttggacaagg aacagacggg cttcctcgcc gaagaagcac cggacaacgt
    12121 taaaaccatg ctccgcagca aaggctattt cagcagcaaa gtcagcctga cggaaaaaga
    12181 cggagcttat acggtacaca tcacaccggg cccgcgcacc aaaatcgcca acgtcggtgt
    12241 cgccatcctc ggcgacatcc tttcagacgg caacctcgcc gaatactacc gcaacgcgct
    12301 ggaaaactgg cagcagccgg taggcagtga tttcgatcag gacagttggg aaaacagcaa
    12361 aacttccgtc ctcggcgcgg taacgcgcaa aggctacccg cttgccaagc tcggcaacac
    12421 ccgggcggcc gtcaaccccg ataccgccac cgtcgatttg aacgtcgtcg tggacagcgg
    12481 ccgccccatc gccttcggcg actttgaaat caccggcaca cagcgttacc ccgaacaaat
    12541 cgtctccggc ctggcgcgct tccaaccggg cacgccctac gacctcgacc tgctgctcga
    12601 cttccaacag gcactcgaac aaaacgggca ttattccggc gcgtccgtac aagccgactt
    12661 cgaccgtctc caaggcgacc gcgtccccgt caaagtcagc gtaaccgagg tcaaacgcca
    12721 caagctcgaa accggcatcc gcctcgattc ggaatacggt ttgggcggca aaatcgccta
    12781 cgactattac aacctcttca acaaaggcta tatcggctcg gtcgtctggg atatggacaa
    12841 atacgaaacc acgcttgccg ccggcatcag ccagccgcgc aactatcggg gcaactactg
    12901 gacaagcaac gtttcctaca accgttcgac cacccaaaac ctcgaaaaac gcgccttctc
    12961 cggcggcatc tggtatgtgc gcgaccgcgc gggcatcgat gccaggctgg gggcagagtt
    13021 tctcgcagaa ggccggaaaa tccccggctc ggatgtcgat ttgggcaaca gccacgccac
    13081 gatgctgacc gcctcttgga aacgccagct gctcaacaac gtgctgcacc ccgaaaacgg
    13141 ccattacctc gacggcaaaa tcggtacgac tttgggcaca ttcctgtcct ccaccgcgct
    13201 gatccgcacc tctgcccgcg caggttattt cttcacgccc gaaaacaaaa aactcggcac
    13261 gttcatcata cgcggacaag caggttacac cgttgcccgc gacaatgccg acgttccttc
    13321 ggggttgatg ttccgcagcg gcggcgcgtc ttccgtgcgc ggttacgaac tcgacagcat
    13381 cgggcttgcc ggcccgaacg gatcggtcct gcccgaacgc gccctcttga cgggcagcct
    13441 ggaataccaa ctgccgttta cgcgcaccct ttccggcgcg gtattccacg atatgggcga
    13501 tgccgccgcc aatttcaaac gtatggagct gaaacacggt tcgggactgg gcgtgcgctg
    13561 gttcagcccg ctcgcgccgt tttccttcga catcgcctac gggcacagcg ataagaaaat
    13621 ccgctggcac atcagcttgg gaacacgctt ctaaaccgat acggccgctt cagacggcat
    13681 tgcagcaaac tattttgaaa cagacattat gaccgatacc gcaccgacag ataccgatcc
    13741 gaccgaaaac ggcacgcgca aaatgccgtc tgaacaccgc cccaccccgc cggcaaaaaa
    13801 acgccgcccg ctgctgaagc tgtcggcggc actgctgtct gtcctgattt tggcagtatg
    13861 tttcctcggc tggctcgccg gcacggaagc gggtttgcgc ttcgggctgt accaaatccc
    13921 gtcttggttc ggcgtaaaca tttcctccca aaacctcaaa ggcacgctgc tcgacggctt
    13981 cgacggcgac aactggtcga tagaaaccga gggggcagac cttaaaatca gccgcttccg
    14041 cttcgcgtgg aaaccgtccg aactgatgcg ccgcagcctg cacattaccg aaatttccgc
    14101 cggcgacatc gccatcgtta ccaaaccgac tccgcctaaa gaagaacgcc cgccgctcag
    14161 ccttcccgac agcatagacc tgcctgccgc cgtctatctc gaccgcttcg agacgggcaa
    14221 aatcagcatg ggcaaagcct ttgacaaaca aaccgtctat ctcgaacggc tggatgcttc
    14281 ataccgttac gaccgcaaag gacaccgcct tgacctgaag gccgccgaca cgccgtggag
    14341 cagttcgtcg gggtcagcct cggtcggctt gaaaaaaccg tttgccctcg ataccgccat
    14401 ttacaccaaa ggcggactcg aaggcaaaac catacacagt acggctcggc tgagcggcag
    14461 cctgaaggat gtgcgcgccg aactggcgat cgacggcggc aatatccgcc tctcgggaaa
    14521 atccgtcatc cacccgtttg ccgaatcatt ggataaaaca ttggaagaag tactggtcaa
    14581 agggttcaac atcaatccgg ccgccttcgt gccttccctg cccgatgccg gactgaattt
    14641 cgacctgacc gccatcccgt cgttttcaga cggcatcgcg ctggaaggtt cgctcgattt
    14701 ggaaaacacc aaagccggct ttgccgactg caacggcatc cccgtccgtc aggttttagg
    14761 cggctttgtc atccggcagg acggcacggt gcatatcggc aatacgtccg ccgccctgct
    14821 cggacggggc ggcatcaggc tgtcgggcaa aatcgacacc gaaaaagaca tcctcgattt
    14881 aaatataggc atcaactccg tcggcgcgga agacgtactg caaaccgcgt tcaaaggcag
    14941 gttggacggc agcatcggca tcggtggcac gaccgcctcg cccaaaatct cttggcaact
    15001 cggcatcggc acggcgcgca cggacggcag cctcgccatt gcaagcgacc ccgcaaacgg
    15061 acagcggaaa ctggtgctcg acaccgtcaa catcgccgcc gggcaaggca gcctgaccgc
    15121 gcaaggctat ctcgagctgt ttaaagaccg cctgctcaag ctggacatcc gttcccgcgc
    15181 attcgaccct tcgcgcatca atccgcaact tccggcaggc aatatcaacg gctcaataaa
    15241 ccttgccggc gaactggcaa aagagaaatt cacaggcaaa atgcggtttt tacccggcac
    15301 gttcaacggc gtaccgattg ccggcagtgc cgacattgtt tacgagtccc gccaccttcc
    15361 gcgtgccgcc gtcgatttgc ggctggggcg gaacatcatc aaaacagacg gcggcttcgg
    15421 caaaaaaggc gaccggctta acctcaatat caccgcaccc gatttatccc gtttcggttt
    15481 cggactcgcg gggtctttaa atgtacgcgg acacctttcc ggcgatttgg acggcggcat
    15541 ccgaaccttt gaaaccgacc tttccggcgc ggcgcgcaac ctgcacatcg gcaaggcggc
    15601 agacatccgt tcgctcgatt tcaccctcaa aggttcgccc gacacaagcc gcccgatacg
    15661 cgccgacatc aaaggcagcc gcctttcgct gtcgggcgga gcggcggttg tcgataccgc
    15721 cgacctgatg ctggacggca cgggcgtgca gcaccgcatc cgcacacacg ccgccatgac
    15781 gctggatggc aaaccgttca aattcgattt ggacgcttca ggcggcatca acagggaact
    15841 tacccgatgg aagggcagca tcggcatcct cgacatcggc ggcgcattca acctcaagct
    15901 gcaaaaccgt atgacgctcg aagccggtgc ggaacgcgtg gcggcaagtg cggcaaattg
    15961 gcaggcaatg ggcggcagcc tcaacctgca acacttttcc tgggacagga aaaccggcat
    16021 atcggcaaaa ggcggcgcac gcggtctgca tatcgccgag ttgcacaatt tcttcaaacc
    16081 gcccttcgaa cacaatctgg ttttaaacgg cgactgggat gtcgcctacg ggcgcaacgc
    16141 gcgcggctac ctcaatatca gccggcaaag cggcgatgcc gtattgcccg gcgggcaggc
    16201 tttgggtttg aacgcatttt ccctgaaaac gcgctttcaa aacgaccgca tcggaatcct
    16261 gcttgacggc ggcgcgcatt tcgggcggat taacgccgat ttggacatcg gcaacgcctt
    16321 cggcggcaat atggcaaatg caccgctcgg cggcaggatt accgcctccc ttcccgactt
    16381 gggcgcattg aagccctttc tgcccgccgc cgcgcaaaac attaccggca gcctgaatgc
    16441 cgccgcgcaa atcggcggac gggtcggctc tccgtccgtc aatgtcgccg tcaacggcag
    16501 cagcaactac gggaaaatca acggcaacat caccgtcggg caaagccgct ctttcgatac
    16561 cgcgcctttg ggcggcaggc tcaacctgac cgttgccgat gccgaagtat tccgcaactt
    16621 cctgcccgtc ggacaaaccg tcaaaggcag cctgaatgcc gccgtaaccc tcggcggcag
    16681 catcgccgac ccgcacttgg gcggcagcat caacggcgac aagctctatt accgcaacca
    16741 aacccaaggc atcatcttgg acaacggttc gctgcgttcg catatcgcag gcaggaaatg
    16801 ggtaatcgac agcctgaaat tccgtcacga agggacggcg gaactctccg gtacggtcgg
    16861 tatggaaaac agcggacccg atgtcgatat cggcgcggtg ttcgacaaat accgcatcct
    16921 gtcccgcccc aaccgccgcc tgacggtttc cggcaacacc cgcctgcgct attcgccgca
    16981 aaaaggcata tccgttaccg ggatgattaa aacggatcag gggctgttcg gttcgcaaaa
    17041 atcctcgatg ccgtccgtcg gcgacgatgt cgtcgtatta ggcgaagtca aaaaagaggc
    17101 ggcggcaccg ctccccgtca atatgaacct gactttagac ctcaatgacg gcatccgctt
    17161 cgccggctac ggcgcggacg ttaccatagg cggcaaactg accctgaccg cccaatcggg
    17221 cggaagcgtg cggggcgtgg gcacggtccg cgtcatcaaa gggcgttata aggcatacgg
    17281 gcaggatttg gacattacca aaggcacggt ctcctttgtc ggcccgctca acgaccccaa
    17341 cctcaacatc cgcgccgaac gccgcctttc ccccgtcggt gcgggcgtgg aaatattggg
    17401 cagcctcaac agcccgcgca ttacgctgac ggcaaacgaa ccgatgagtg aaaaagacaa
    17461 gctctcttgg ctcatcctca accgcgccgg cagcggcagc agcggcgaca atgccgccct
    17521 gtccgcagcc gcaggcgcgc tgcttgccgg gcaaatcaac gaccgcatcg ggctggtgga
    17581 tgatttgggc tttacccgca agcgcagccg caacgcgcaa accggcgaac tcaaccccgc
    17641 cgaacaggtg ctgaccgtcg gcaaacaact gaccggcaaa ctctacatcg gctacgaata
    17701 cagcatctcc agcgcggaac agtccgtcaa actgatttac cggctgaccc gcgccataca
    17761 ggcggttgcc cgtatcggca gccgttcgtc gggcggcgag ctgacataca ccatacgttt
    17821 cgaccgcttc tccggttcgg acaaaaaaga ctccgccgga aacggcaaag gaaaataagc
    17881 ggttttcaga cggcgcgccg ccaaaccgga catttgaaaa cctgcttttc caccgtccgc
    17941 cgccgccgtc cgcctgcaag ggaacagaat cgatatagtg aattaacaaa aatcaggata
    18001 aggcgacgaa gccgcagaca gtacaaatag tacggaaccg attcactcgg tgcttgagca
    18061 ccttagagaa tcgttctctt tgagccaagg cgaggcaacg ccgtaccggt ttttgttaat
    18121 ccgctatatt ccgccatctc taagatttac agcgatacac aggtaattta aggaatgccc
    18181 ga
//
LOCUS       DAXISH010000044        17891 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.044, whole genome shotgun sequence.
ACCESSION   DAXISH010000044 DAXISH010000000
VERSION     DAXISH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 17891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17891
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.044"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(225..380)
                     /gene="rpmG"
                     /locus_tag="ACFOV4_001459"
     CDS             complement(225..380)
                     /gene="rpmG"
                     /locus_tag="ACFOV4_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009766925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFC7619442.1"
                     /translation="MRDKIKLESSAGTGHFYTTTKNKRTMPGKLEIKKFDPVARKHVV
                     YKETKLK"
     gene            complement(412..645)
                     /gene="rpmB"
                     /locus_tag="ACFOV4_001460"
     CDS             complement(412..645)
                     /gene="rpmB"
                     /locus_tag="ACFOV4_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007586227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFC7619443.1"
                     /translation="MARVCKVTGKRPMSGNNVSHANNKTKRRFLPNLQSRRFWVESEN
                     RWVRLRVSNAALRTIDKVGIDVVLADLRARGEA"
     gene            complement(895..2421)
                     /gene="farB"
                     /locus_tag="ACFOV4_001461"
     CDS             complement(895..2421)
                     /gene="farB"
                     /locus_tag="ACFOV4_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid resistance MFS efflux transporter
                     permease subunit FarB"
                     /protein_id="HFC7619444.1"
                     /translation="MDYPPLKGAALAWVTLSLGLAVFMEVLDTTIANVAVPVIAGNLG
                     AATTQGTWVITSFAVANAVSVPLTGFLAKRIGEVKLFTAAAVGFVITSWLCGIAPNLQ
                     ALVFFRILQGFIAGPLIPLSQSLLMASYPPAKRTLALALWAMTVVVAPVLGPILGGWI
                     SGNWHWGWIFFINIPIGIISAWITWKHLKYRETETVKMPTDYVGLTLMVVGIGALQMM
                     LDRGKELDWFASGEIITLGVVALVCLSYFIVWELGEKYPIVDLSLFKDRNFTVGVIAT
                     SLGFMVYMGTLTLLPLVLQTNLGYTSTWAGLAAAPVGILPVFLSPIIGRFGNKIDMRL
                     LVTASFLTFAFTFYWRTDFYADMDIGNVIWPQFWQGAGVAMFFLPLTTITLSHMKGGQ
                     IAAAGSLSNFLRVLMGGVGVSFVSTLWERREALHHTRFAEHITPYSATLHETAAHLSQ
                     QGISDIQTLGIINNTITQQGFIIGSNEIFMAGSLLFIIMIPVIWLAKPPFHNGGGGGH
                     "
     gene            complement(2445..3599)
                     /gene="farA"
                     /locus_tag="ACFOV4_001462"
     CDS             complement(2445..3599)
                     /gene="farA"
                     /locus_tag="ACFOV4_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid resistance MFS efflux transporter
                     adaptor subunit FarA"
                     /protein_id="HFC7619445.1"
                     /translation="MDTHTDETKLQNTQAKRKRRLTALTLLFALAAAAAGSAFFLWWQ
                     HEEETEDAYVAGRVVQVTPQKGGTVRKVLHDDTDAVKKGDVLAVLDDDNDVLAYERAK
                     NELVQAVRQNRRQNAATSQAGAQVALRRADLARAQDDLRRRSALAESGAVSAEELAHA
                     RAAVSQAQAAVKAALAEESSARAALGGDVSLREQPAVQTAIGRLKDAWLNLQRTQIRA
                     PADGQVAKRSVQVGQQVAAGAPLMAVVPLSDVWVDANFKETQLRHMKIGQPAELVSDL
                     YGKQIVYRGRVAGFSAGTGSAFSLIPAQNATGNWIKVVQRVPVRIVLNREDVDRHPLR
                     IGLSMTVKVDTSAAGAPVSKTPGAALPEMESTDWSEVDRTVDEILGQSAP"
     regulatory      3993..4037
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            4041..4514
                     /gene="queF"
                     /locus_tag="ACFOV4_001463"
     CDS             4041..4514
                     /gene="queF"
                     /locus_tag="ACFOV4_001463"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HFC7619446.1"
                     /translation="MSRNNEELQGISLLGNQKTRYPTEYAPEILEAFDNKHPDNDYFV
                     KFVCPEFTSLCPMTGQPDFATIVIRYIPHIKMVESKSLKLYLFSFRNHGDFHEDCVNI
                     IMKDLIALMDPKYIEVFGEFTPRGGIAIHPFANYGKAGTEFEALARKRLFEHDAQ"
     gene            4591..5277
                     /locus_tag="ACFOV4_001464"
     CDS             4591..5277
                     /locus_tag="ACFOV4_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1990397 - queuosine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HFC7619447.1"
                     /translation="MYAFTDAQQQKALFRLVLFHILIIAASNYLVQFPFQIFGIHTTW
                     GAFSFPFIFLATDLTVRIFGSHLARRIIFWVMFPALLLSYIFSVLFHDGGWTGLGALS
                     QFNTFVGRIALASFAAYALGQILDIFVFNKLRRLKAWWVAPTASTVIGNALDTLVFFA
                     VAFYASSDGFMAANWQGIAFVDYLFKLTVCGLFFLPAYGVILNLLTKKLTTLQTKQAQ
                     DRPAPSLQNP"
     gene            5317..5427
                     /locus_tag="ACFOV4_001465"
                     /pseudo
     CDS             5317..5427
                     /locus_tag="ACFOV4_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(5885..7177)
                     /locus_tag="ACFOV4_001466"
     CDS             complement(5885..7177)
                     /locus_tag="ACFOV4_001466"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HFC7619448.1"
                     /translation="MAVFPLSAKHRKYALRALAVSIILVSAAYIALTERTERVRPQRV
                     EQNLPPLSWGGSGVQTAYWVQEAVQPGDSLADVLARSGMARDEIARITEKYGGEADLR
                     HLRADQSVHVLVGGDGGAREVQFFTDEDGERNLVALEKKGGIWRRSASEADMKVLPTL
                     RSVVVKTSARGSLARAEVPVEIRESLSGIFAGRFSLDGLKEGDAVRLMYDSLYFHGQQ
                     VAAGDILAAEVVKGGTRHQAFYYRSDKEGGGGGNYYDEDGRVLQEKGGFNIEPLVYTR
                     ISSPFGYRMHPILHTWRLHTGIDYAAPQGTPVRASADGVITFKGRKGGYGNAVMIRHA
                     NGVETLYAHLSAFSQAQGNVRGGEVIGFVGSTGRSTGPHLHYEARINGQPVNPVSVAL
                     PTPELTQADKAAFAAQKQKADALLARLRGIPVTVSQSD"
     gene            7254..8222
                     /locus_tag="ACFOV4_001467"
     CDS             7254..8222
                     /locus_tag="ACFOV4_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619449.1"
                     /translation="MKLTLALPSLNLDEDEIRIPLCLPAFNKILQYGSLHRQSCTASA
                     FYARYLWCGRLAERAAQSLNMPSETVALATPVWQKMGMHQANVLTAEYLDVGTDEAER
                     LCRDLSAFYGDIPWRFVPVLPELWLVSLPRAYRWGAKPVLDLGGLLGADDQPDGEDAL
                     EWLRVQTEIQMWLAAHPVNHNRKKRGLPELNGLWLWGGTNGGTQGGTLFADTVWSRFH
                     PDRRALPDNFRAYEETAAHLPDTHHILFMDDLRLTALTGDRERYAAILQQWEERWFAP
                     LYEAVRIGKIKRLDIATDGQHGGTLTFKPADRWKFWRGAKTFDGIW"
     gene            complement(8423..9886)
                     /locus_tag="ACFOV4_001468"
     CDS             complement(8423..9886)
                     /locus_tag="ACFOV4_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein assembly modifier"
                     /protein_id="HFC7619450.1"
                     /translation="MVIFYFCGKTFMPARNRWMLLPLLASAAYAEETPREPDLRSRPE
                     FRLHEAEVKPIDREKVPGQVREKGKVLQIDGETLLKNPELLSRAMYSAVVSNNIAGIR
                     VILPIYLQQAQQDKMLALYAQGILAQADGRVKEAISHYRELIAAQPDAPAVRMRLAAA
                     LFENRQNEAAADQFDRLKAENLPPQLMEQVELYRKALRERDAWKVNGGFSVTREHNIN
                     QAPKRQQYGKWTFPKQVDGTAVNYRLGAEKKWSLKNGWYTTAGGDVSGRVYPGNKKFN
                     DMTAGVSGGIGFADRRKDAGLAVFHERRTYGNDAYSYTNGARLYFNRWQTPKWQTLSS
                     AEWGRLKNTRRARSDNTHLQISNSLVFYRNARQYWMGGLDFYRERNPADRGDNFNRYG
                     LRFAWGQEWGGSGLSSLLRLGAAKRHYEKPGFFSGFKGERRRDKELNTSLSLWHRALH
                     FKGITPRLTLSHRETRSNDVFNEYEKNRAFVEFNKTF"
     gene            complement(10128..12242)
                     /locus_tag="ACFOV4_001469"
                     /pseudo
     CDS             complement(10128..12242)
                     /locus_tag="ACFOV4_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581764.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(13708..13953)
                     /locus_tag="ACFOV4_001470"
     CDS             complement(13708..13953)
                     /locus_tag="ACFOV4_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619451.1"
                     /translation="MLKSIELNSHVRNRLAAYLKGRGMDFQTAMQEEEGNKEIAAIVH
                     SGLPTLVRKLYSEQKMQKFFWEKRDLIADYISRRMQG"
     gene            14070..14495
                     /locus_tag="ACFOV4_001471"
     CDS             14070..14495
                     /locus_tag="ACFOV4_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopD family protein"
                     /protein_id="HFC7619452.1"
                     /translation="MYSWFKLFHLFFVISWFAGLFYLPRIFVNMAMIDAPRGNPEYVR
                     LSDMAVRLYRFMSPLGFGAVVFGAAIPFAAGWWGSGWVHVKLCLGLILLAYQLYCGVL
                     LRRFQDYSNAFSHRWYRVFNEIPVLLMVAALYLVVFKPF"
     gene            14507..14983
                     /locus_tag="ACFOV4_001472"
     CDS             14507..14983
                     /locus_tag="ACFOV4_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFC7619453.1"
                     /translation="MPIEIERRFLIGNDNWRQYADEPLLLRQGYLSVEKERTVRVRIA
                     GQRAWLTLKGYISEISRSEFEYEIPLADAEKMMETMCPFKMEKWRYPVRWGGSLFEID
                     VFLGENAPLVVAEIELPDENADFDRPDWLGREITADGMFTNAYLSRHPFSSWKNAV"
     gene            complement(15333..15821)
                     /locus_tag="ACFOV4_001473"
     CDS             complement(15333..15821)
                     /locus_tag="ACFOV4_001473"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFC7619454.1"
                     /translation="MLKITLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIM
                     GRKTWESLPVKPLPGRRNIVISRQADYCAAGAETAASLEAALALCAGAEEAVIMGGAQ
                     IYGQAMPLATDLRITEVDLSVEGDAFFPEIDRTHWKEAGRTERRVSSKGTRYAFVHYL
                     RY"
     gene            complement(15889..16944)
                     /gene="aroG"
                     /locus_tag="ACFOV4_001474"
     CDS             complement(15889..16944)
                     /gene="aroG"
                     /locus_tag="ACFOV4_001474"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HFC7619455.1"
                     /translation="MTHHYPTDDIKIKEVKELLPPIAHLYELPISKEASGLVHRTRQE
                     ISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRT
                     TVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLIS
                     WGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAG
                     HSAIVHTGGNPDCHVILRGGKEPNYDAGHVSEAAEQLRAAGVTDKLMIDCSHANSRKD
                     YTRQMEVAQDIAAQLEQDGSNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEE
                     LLALLAGANKKRMARAG"
     gene            17572..17868
                     /locus_tag="ACFOV4_001475"
                     /pseudo
     CDS             17572..17868
                     /locus_tag="ACFOV4_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212265.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4195 a         4959 c         4378 g         4359 t
ORIGIN      
        1 ttatagtgga ttaacaaaaa tcaggacaag gcgacgaagc tgcagacagt acaaatagta
       61 cggaaccgat tcacttggtg cttcagcacc ttagagaatc gttctctatc cttggcagac
      121 ggtttgcagc agattcgcat acggcagatg tttcaagcgg aaaagaaaca cgataaaaat
      181 aaaaaagcct ccgaacagtc ggaggctttg ctttcaaact gaaattattt cagtttggtt
      241 tctttgtaca ctacgtgttt gcgggcaacc ggatcgaatt ttttaatttc cagtttgccg
      301 ggcatagtgc gtttattttt ggtagtggtg tagaagtgac cagtacctgc actggattcc
      361 agtttgattt tatcgcgcat tgcagtaatc cttaattaaa tagtgtttaa attaagcttc
      421 gccgcgagca cgcaaatcag ccaatacgac atcaatgcct actttgtcga tggtacgcag
      481 tgcagcgttg gaaacgcgca ggcgaaccca gcggttttca ctttctaccc aaaaacgacg
      541 tgattgcaag ttgggcaaaa aacggcgttt ggttttgttg ttggcgtgcg atacgttgtt
      601 gccggacatc gggcgtttgc cggtcacttt gcaaactcgt gccataatca gtctccaaac
      661 ttctaaaata gtaaaacgcg atttatacca cgaaaaacag tgttagttca agtgttttaa
      721 agaaaaacgg ctgttttgcg cggataatcc ttccgattgt cgcatctgtg gaacgtttgc
      781 aggtgcgaaa cagatggggc gcgattatag cggatttcgg gaactgctgc attcaaaatg
      841 ccgtccgaac atatttccag tattttcaga cggcatttca agttttcaaa tccctcaatg
      901 tccaccgccg ccgccgttgt ggaacggcgg ttttgccagc catatgacag gaatcatgat
      961 gatgaacagc aggctgcctg ccataaagat ttcattcgat ccgatgatga agccctgctg
     1021 ggtaatggta ttgttgatga tacctagggt ttgaatgtcg gaaatgcctt gttgggacaa
     1081 atgcgccgcc gtttcgtgca atgttgcgga atagggcgtg atgtgttcgg caaagcgtgt
     1141 gtggtgcaac gcttcgcgcc gttcccacag ggtactgacg aatgatacgc cgacaccgcc
     1201 catcagcacg cgcaagaaat tcgacaggct gccggcggcg gcaatctgtc cgcccttcat
     1261 atgcgacagt gtgatggtgg tcagcggcag gaagaacatg gcaacgcctg ccccctgcca
     1321 aaactgcggc cagatgacgt tgccgatatc catgtcggca taaaaatcgg tgcgccaata
     1381 gaaagtgaag gcaaaagtca ggaagctggc ggttacgagc aggcgcatat cgattttatt
     1441 gccgaacctg ccgataatgg gggacaggaa gacgggcagg atgccgacgg gtgcggcggc
     1501 aagccccgcc cacgtggagg tatagcccag gttggtctgc aacactaacg gcagcaaggt
     1561 cagcgtcccc atatacacca taaaacccaa tgatgtggca attacgccga cggtaaaatt
     1621 ccgatcttta aacagcgata aatcgacaat cggatatttt tctcccaatt cccaaacaat
     1681 aaaatacgac aaacacacca gtgcgactac gcccaaggta atgatttctc cagaggcgaa
     1741 ccagtcgagt tccttacccc tgtccagcat catctgtaac gcgccgatac cgactaccat
     1801 caatgtaagc ccgacatagt cggtcggcat tttaacggtt tccgtttccc gatatttcaa
     1861 atgtttccat gtaatccatg ccgatatgat accgataggg atattaatga agaaaatcca
     1921 accccaatgc cagtttccgg aaatccagcc gccgagtatc ggcccgagaa caggggcgac
     1981 aacgacggtc attgcccaca atgccagtgc cagcgtccgt tttgcgggcg gataggatgc
     2041 cattaacagg ctttgcgaca ggggaatcag cggcccggcg ataaaaccct gcaagatgcg
     2101 gaaaaacacc aaagcctgaa ggttgggcgc gatgccgcac agccatgatg tgatgacgaa
     2161 accgacagcg gcggcggtaa acagtttgac ctcgccgata cgttttgcca aaaagcccgt
     2221 taacggcacg gaaacggcgt ttgccacagc aaaagaagta atgacccacg tcccctgcgt
     2281 ggttgccgca ccgaggttgc cggcgatgac gggaacggcg acattggcga tagtcgtatc
     2341 taaaacttcc ataaatacgg caagccccaa agacagcgta acccacgcca atgccgcacc
     2401 cttaagcggt ggataatcca ttgtgtcctc cgtttcagac ggcatcaggg cgcggattgc
     2461 ccgaggattt catcgaccgt ccgatcgact tccgaccagt cggtactttc catttccggc
     2521 aatgccgcac ccggcgtttt tgaaacaggc gcgcctgcgg cggaagtatc cactttaacc
     2581 gtcatcgaca aaccgatacg caacggatgc ctgtccacat cttcgcggtt cagcacgata
     2641 cggacgggga cgcgctgcac cactttaatc cagttgcccg ttgcgttttg cgccggaatc
     2701 agcgaaaacg cgctgcccgt acctgccgaa aaccctgcca ccctgccgcg ataaacaatt
     2761 tgtttgccgt acaaatcgga caccagttcg gcaggctgtc cgattttcat atgccgcaac
     2821 tgcgtctctt taaaattggc atccacccac acatccgaca gcggcaccac cgccatcagc
     2881 ggcgcgcctg ccgccacctg ctgcccgacc tgcaccgaac gcttcgccac ctgaccgtcc
     2941 gccggcgcgc ggatttgcgt ccgctgaagg ttcaaccacg catctttcaa cctgccgatt
     3001 gccgtctgaa ccgccggctg ttcgcgcaaa gaaacatctc cgcccaaagc cgcgcgtgcc
     3061 gaagattctt ccgccaaagc cgctttgacc gccgcctgcg cctgagacac tgccgcacgg
     3121 gcgtgtgcca gctcttcggc ggacaccgcg cccgattccg ccaaagcaga ccggcggcgc
     3181 aaatcatcct gtgcgcgtgc caaatccgcc cggcgcaagg caacctgcgc ccccgcctgc
     3241 gaagtggcgg cattttgccg gcggttttgc cgcaccgcct gaaccagctc gttttttgcc
     3301 cgctcgtaag ccagcacatc attatcgtcg tccaataccg ccagcacgtc gccttttttc
     3361 acggcatccg tatcgtcgtg caaaaccttc cgcaccgtac cgcccttttg cggcgtaacc
     3421 tgaaccacgc gtccggcaac ataagcgtct tccgtttcct cttcgtgctg ccaccataaa
     3481 aaaaacgccg acccggcggc tgcggcggca agcgcgaaca gcagcgtcaa tgccgtcagg
     3541 cggcgtttgc gtttagcttg cgtgttttga agttttgttt cgtccgtgtg cgtatccata
     3601 agattgggtt ccgaatttcc tgatttcata taaacaatgt tctttcaata ggaagcagat
     3661 tctatatccg cgcaataacg caatcaagtc agtattttag atgcaatatt caaaaaacaa
     3721 cgcttcaggc ggcaaaactg aaaatatatt tcgtttatat aatggattaa caaaaatcag
     3781 gacaaggcgg cgaagccgca gacagtacaa atagtacgga accgattcac ttggtgcttc
     3841 agcaccttag agaatcgttc tctttgagct aaggcgaggc aacgccgtac tggtttttgt
     3901 taatccacta tatatgacac ggaaaacgcc gccgtccaaa ccatgccgtc tgaagaaaac
     3961 tacacagata ccgccgctta tattacaatc gccgccccgt ggttcgaaaa cctcccacac
     4021 taaaaaacta aggaaaccct atgtcccgca acaacgaaga gctgcaaggc atctcgcttt
     4081 tgggtaatca gaaaacccga tacccgaccg aatacgcgcc cgaaattttg gaagcattcg
     4141 acaacaaaca tcccgacaac gactatttcg tcaaattcgt ctgcccagag ttcaccagcc
     4201 tctgccccat gaccgggcag cccgacttcg ccaccatcgt catccgctac attccgcaca
     4261 tcaaaatggt ggaaagcaaa tccctgaaac tctacctctt cagcttccgc aaccacggcg
     4321 attttcatga agactgcgtc aacatcatca tgaaagacct cattgccctg atggatccga
     4381 aatacatcga agtattcggc gagttcacac cgcgcggcgg catcgccatt catcctttcg
     4441 ccaattacgg caaagcaggc accgagtttg aagcattggc gcgtaaacgc ctgtttgagc
     4501 acgacgcaca ataaaccatc cttcccatat ttcagacggc attctttcga tacggtatgc
     4561 cgtctgaacg cctttccgaa aggttttttt atgtacgcat ttaccgacgc acagcaacag
     4621 aaggcactct tccggctggt gctttttcat atccttatca tcgccgccag caactatctg
     4681 gtgcagttcc ccttccaaat tttcggcatc cacaccactt ggggcgcatt ttcctttccc
     4741 ttcatcttcc ttgccaccga cctgaccgtc cgcattttcg gttcgcactt ggcacggcgg
     4801 attatctttt gggtgatgtt ccccgccctt ttgctttcct atatcttttc cgttttgttc
     4861 cacgacggcg gttggacggg cttgggcgcg ctgtcccaat tcaacacctt tgtcggacgc
     4921 atcgccttag ccagctttgc cgcctatgcg ctcggacaaa tccttgatat ttttgtattc
     4981 aacaaattac gccgtctgaa agcgtggtgg gttgccccaa ccgcatcaac cgtcatcggc
     5041 aacgccttgg atacgttggt atttttcgcc gttgccttct acgcaagcag cgatggattt
     5101 atggcggcaa actggcaggg catcgctttt gtcgattacc tgttcaaact taccgtctgc
     5161 ggtctgtttt tcctgcccgc ctacggcgtg attctgaatc tgctgacgaa aaaactgacg
     5221 accctgcaaa ccaaacaggc gcaagaccgc cccgcgccct cgctgcaaaa tccgtaaaac
     5281 agccctgccg ggaatcggga cggttgggtt ttcttttata gtggattaaa tttaaatcag
     5341 gacaaggcga cgaagccgca gacagtacag atagtacggc aaggcgaggc aacgccgtac
     5401 cggtttaaat ttaatccact atatttgcaa acactgccgg aacggataaa tccggattcc
     5461 tacccacttc gtcattcccg cgaaagcggg aatccggtgc attgagtttc agtcatttcc
     5521 gataaactcc tgccgcgttg catttctaga ttcccgcttt cgcgggaatg acgacggatg
     5581 ggtttccgtg ccgtggcgtc cggattcccg ccggtacagg aatgacggca gtgcttcctt
     5641 ggcttagttt cattttaatc aactgcatag tggattaaca aaaatcagga caaggcgacg
     5701 aagccgcaga cagtacaaat agtacggaac cgatccactt ggtgcttcag caccttagag
     5761 aatcgttctc tttgagctaa ggcgaggcaa cgctgtactg gtttttgtta atccactata
     5821 aatgccgtct gaaaacctgt ttgcagattt tcagacggca ttgttttcgt cgccggttca
     5881 aacttcaatc cgattgcgac acggtaaccg gtatgccgcg caagcgcgca agcagcgcgt
     5941 ccgccttctg tttctgcgcg gcaaacgccg ccttgtccgc ctgcgtcaat tcgggtgtcg
     6001 gcaatgcgac tgaaacagga ttaacgggct gcccgttgat gcgcgcctcg taatgcaggt
     6061 gcggcccggt cgaacgcccg gtcgaaccga caaaaccgat gacctcgccg ccgcgcacat
     6121 tgccttgtgc ctgcgaaaac gcgctcaagt gcgcgtacag cgtttccacg ccgttggcgt
     6181 ggcgtatcat caccgcgttg ccgtatccgc ccttccggcc tttaaaggta atcacgccgt
     6241 cggcggaagc cctgaccggc gttccctgcg gtgcggcata atcgatgccc gtgtgcagcc
     6301 gccatgtgtg caggatgggg tgcatacggt agccgaacgg cgaagaaatg cgcgtataga
     6361 ccagcggctc gatgttgaag ccgccttttt cctgcaacac cctgccgtct tcatcataat
     6421 aattgccgcc ccctccgcct tccttgtccg aacggtaata gaatgcctga tgccttgtgc
     6481 cgcccttaac gacttcagcc gccaaaatat cgcccgccgc cacctgctgc ccgtggaaat
     6541 acaggctgtc gtacatcagg cgcacggcat cgccttcctt caaaccgtca aggctgaagc
     6601 ggccggcgaa aatcccgctt aaggattcgc ggatttcgac gggcacttcc gcccgcgcca
     6661 gcgaaccgcg cgccgacgtt ttgaccacga ccgaacgcag cgtcggcaaa accttcatat
     6721 ccgcctcaga agccgaccgc cgccatatgc cgcctttctt ttccaaagcg accagattgc
     6781 gctcgccgtc ttcgtcggta aaaaactgta cttcgcgcgc gccgccgtcg ccgccgacca
     6841 aaacatgaac cgactggtcg gcacgcaaat gccgcaaatc ggcttcgccg ccatattttt
     6901 ccgtgattcg ggcaatctcg tcccgcgcca tacccgaacg cgccagcacg tccgccagcg
     6961 agtcgcccgg ctgcaccgcc tcctgcaccc aatatgccgt ctgaacgccg ctgccgcccc
     7021 aagacagcgg cggcagattt tgttccacgc gctgcggtct gacgcgttcc gtcctctctg
     7081 tcaaagcaat gtatgccgcc gacaccaaaa taatcgaaac ggcaagcgcg cgcagcgcgt
     7141 atttccgatg ttttgccgaa agtgggaaga cagccatatt gttccttttt gacggcgttt
     7201 gcgccgaatc ctctataata tccgcccgat ccgcatttgt cagacatcaa acgatgaaac
     7261 tcaccctcgc cctcccctcg ctcaatttgg atgaagacga aatccgaata cctctatgcc
     7321 tgcccgcctt caacaaaatc ctgcaatacg gctcgctgca ccgccaaagc tgcacggctt
     7381 cggcatttta cgcgcgttat ttgtggtgcg gcagactggc ggaacgcgcg gcgcaaagcc
     7441 tgaatatgcc gtctgaaacc gtcgcgctcg ccacgcccgt ctggcaaaag atggggatgc
     7501 atcaggcaaa tgtgctgacg gcggaatatt tggatgtcgg tacggatgaa gcggaacggc
     7561 tctgccgcga tctgtcggcg ttttacggcg atattccgtg gcgtttcgtt cccgtcctgc
     7621 ccgaattatg gctggtttcc cttccccgcg cgtaccgctg gggcgcgaag cccgttttgg
     7681 acttgggcgg attgttgggc gcggacgatc agccggacgg agaagatgcg ttggaatggc
     7741 tgcgcgtcca aaccgaaatc caaatgtggc tggcggcgca ccccgtcaac cataaccgca
     7801 agaaacgcgg gctgcccgag ttgaacggct tatggctttg gggcggcaca aacggcggca
     7861 cgcaaggcgg cacgcttttc gccgatacgg tttggagccg tttccacccc gaccgccgcg
     7921 cattgcccga caacttccgc gcctatgaag aaacggcggc acacctgccc gacacgcacc
     7981 atatcctgtt tatggacgat ttgcgcctga ccgccctgac aggggacagg gagcggtatg
     8041 cggcaatatt gcagcagtgg gaagaacgct ggttcgcacc gctttacgaa gccgtccgca
     8101 tcggcaaaat caaacggctg gacatcgcca cggacggaca acacggcggt acgctgacct
     8161 tcaaacccgc cgacaggtgg aaattttggc gcggcgcgaa aacctttgac ggaatctggt
     8221 gaacccgccc gccgcaaccg cgacaatgcc gtctgaagcc cgaatcgggt ttcagacggc
     8281 attttacctc gcatcgccgt tatgccggaa aaaccggaat gcgtttccgc acacgcggcg
     8341 gcacacaaag caccgcccga aagccgccga tgcccgccgt gataccgccg ccggcagggt
     8401 ttcctccgaa aaggaacagc aatcagaacg ttttattaaa ctcgacaaac gcccgatttt
     8461 tctcgtattc gttgaacaca tcgttactcc gcgtttcgcg gtgcgacaac gtcaggcgcg
     8521 gcgtgatgcc tttgaaatgc aatgcccggt gccaaaggct caaggatgtg ttcaattctt
     8581 tatccctgcg cctttcccct ttaaaaccgc tgaaaaagcc gggtttttca taatgccgtt
     8641 tcgccgcgcc gaggcgcaac agcgaagaca ggccgctgcc gccccattcc tgcccccagg
     8701 caaagcgcag gccgtaacgg ttgaaattgt cgccccggtc ggcggggttg cgctcgcggt
     8761 aaaaatccaa accgcccatc caatattggc gcgcattccg gtaaaacacc agcgaattgg
     8821 aaatttgcaa atgggtattg tcggaacgcg cccggcgcgt attcttcaaa cgcccccact
     8881 ccgccgaaga caacgtttgc catttcgggg tttgccaacg gttgaaataa aggcgtgcgc
     8941 cgttggtgta agaataagcg tcgttgccgt aggtgcggcg ttcgtggaac actgccagcc
     9001 cggcatcttt gcgccggtcg gcaaaaccga tgccgccgga aacgcctgcc gtcatatcgt
     9061 tgaatttctt attccccgga taaaccctgc cggacacgtc gccgcccgcc gtcgtgtacc
     9121 agccgttttt cagcgaccat tttttctccg cgccgagccg gtaattgacc gccgtgccgt
     9181 ccacctgttt cgggaaagtc catttgccgt actgctgccg tttcggggct tggttgatat
     9241 tgtgttcgcg ggtgacgctg aagccgccat ttaccttcca cgcatcgcgt tcgcgcaatg
     9301 ccttgcggta cagctcgacc tgctccatca gctgcggcgg caggttttcc gccttcaggc
     9361 ggtcgaactg gtctgccgcc gcctcgttct gcctgttttc aaacaatgcc gccgccaaac
     9421 gcatacggac ggcgggcgcg tcgggttggg cggcaatcaa ttcccggtaa tgggaaatcg
     9481 cctccttcac cctaccgtct gcctgcgcca aaatcccttg tgcataaagt gccaacatct
     9541 tatcctgctg cgcctgttgt aggtaaatcg gcaaaataac gcggataccg gcaatattgt
     9601 ttgagaccac tgcggaatac atcgcgcggg acaacaattc gggatttttc agcagggttt
     9661 ctccgtcaat ctgcaaaact tttccttttt cccgcacctg ccccggtacc ttctccctgt
     9721 cgattggttt gacctccgct tcatgaagcc tgaactcggg acggcttctc aaatccggtt
     9781 cgcgcggtgt ttcttcggca tatgccgcgc ttgccaataa aggcagcagc atccatctgt
     9841 ttcgtgcagg cataaatgtc ttcccacaaa aataaaaaat aaccattatc aatcggcgga
     9901 ttgtatcagt tttttatgcc gctgttccaa accctgccgc ccgatgccgc gacaatgccg
     9961 tctgaagcca gaatcgggtt tcaaacggcg gcaaaaaacc ggcggttttc cgccggtttc
    10021 atcatgatgc cccgcccttc ggggcggcag ggttcggatt ggtttgcggg gcggcgcgcg
    10081 gggccgtgcc ggtgtgccgc ctgtgcgtca aaacatttcc cgacgcatca aaacagccat
    10141 ttgagcgaca atgcggcttc tttgtcgccg tccgtccttt tgccgtatcc gatgcgtgcg
    10201 gacatatggc ctttccaacc ggcttcaatg ccgaaccgcc cttcgagcgc cgtcctgcct
    10261 gccagcgtct gtttttcgcc gtccatttcc acgccgaaag attttgacct gtgcaaaaca
    10321 ttaaaagcgg cgaaaggctg aagattgaca ccgttacgca aagcaaaacg ggtttttgcc
    10381 cgaataccgg cgcggctttg ccactgaccg ctgccgagca gtccgaccgc cgtcccctcg
    10441 ctgtcggtaa agccgccgtt tacgcccaag taggtaaact gagcctgcgg ttgcaggtaa
    10501 aaccgcacat tattgccttt tccgacaacg ccttccgcca caagcgcgtt gtagccgcct
    10561 tcgacagaag ccgtccaacc tttggttttg tagcgttcca cacggttttc atcattgatg
    10621 cggtgtttga aacgttggta ttgcaaccag ccgtccaaat acgcacccgt ttgtttatcg
    10681 cgcaactgat gccacgcagc ataaacaccc ccgccataac catgcaaata actgcctgcc
    10741 gcaccgcctt tgccgttgac tgatgcgtgc tggccggccc tgccgcccat cacgccgatt
    10801 gccagccggc tgccttcatt ttgccgtaca aacacctcgc cgccgatttg cacgcctttg
    10861 cgccgcccgt ccgcagccgc gccgccccgt atattttgat gcgaccggcc gccgatgaag
    10921 cgcagccaca atttttgacg ggacggatcg gcggcataca cgtcgtctcc cctgtcggcg
    10981 gcacgcagcc caaacaaagt atttgccgca taagcctgtt gggcatataa aaccgcttcc
    11041 gcctcgggga tagccaaacg ctgcacgccc aagcaaaatc cgccttcgca ttgcttgagc
    11101 aataattcgt acagtccctg ccggtaattt tgtttaaacg caaacgaatt agggtctgcc
    11161 ttttccgccg caatcagttt gcgcccgtcg agcgttttca gattttccgg ccggcgttcc
    11221 aaaaccacgc cggattgtcc gctgactttg tcttcaaagg tcagggcggg ttcgtccgac
    11281 tcccgcacgt cgtagccgaa caggaaatcc gcgccgccct gatacgcttt atggacggtc
    11341 agtttttcat ctttcgtgtt caggcggatc cgggcattat cggaagtttc cagcatatgg
    11401 atgtcggaat ggcggcgcgg ttcccaaagg gaatctttca gcgtcatctt ggtcagttcc
    11461 aacacctgtc cggcgacgtg ggatttgttt tcgattttga cgtgtaattt tttattgaag
    11521 atgttgttga gactagtctg tgatgtatta ctatgaggag tgagtacgga atcttctacc
    11581 aatttattaa ttaaatcggg gtttttctgt ttgagtatac taaattttgg tccaagctgt
    11641 tctatatacg cctcctcagt ccgtttttta ttttcttccc aagcttcggg tcttgttttg
    11701 tataaatcct gtaattgctt cttaaccgca tcctttaaat tatccccgta agtatctgta
    11761 atatatttct taacaacggg catattatcg acggcgagta tgccgctatt gtagttttta
    11821 ccttggatat tgatttcgtc atacccatat tcggatgaat tttgatcggt tttaccgctg
    11881 gaaaaataat gggaagtgcc gggtttcggc ttgtctgaaa atgaaaaatc ggcatcgtcg
    11941 ccgattttgg tagaacgagt atttgaacca agctgagctc tgaacatacc gaagcaatca
    12001 aaagatatgc tgcacgggcc gcgccaaacg tgggaatttc tgtcttccgc cgcttctaaa
    12061 ataaatttgt ttttaatctc ggcttctttg acgggatcgt acgcatccga acctcaaaca
    12121 tatggcgtgc aaaacagcga taaaacagat aatgttaata gattaacccg accgcttgct
    12181 tgcttgcttg cttgcttgct tgcttgcttg cttgcttgct tgctttcagt gtcatgagaa
    12241 attttccttt gtcaagtgtt aaaattataa tgattatata ctacattata ctacatcgca
    12301 atgaaaaatc aggaaaagca aaaaaccctc cgccgtcatt cccgcgaaag cgggaatcta
    12361 gaattttaat gccgcaagaa tttatcaagg atggtcgggg tttaaaggtc tggattcccg
    12421 cctgcgcggg aatgacggtt tagaaatcac ccgaaacaag aaaaagaacc gaaaccgaac
    12481 aagccggatt cccgcctgcg cgggaatgac gggatttcag gttactgttt ttgattttct
    12541 gtttttgtgg gaataacggg actttggatg atgtgcattt atcgagaaaa ctaaaaaccc
    12601 tccgccgtca ttcccgcgaa agcgggaatc tagacctttc ggtgcggaaa cttatcggat
    12661 aaaacggttt tccctgcatc ctggattccc actttcgtgc gaatgacggg atataggttt
    12721 cactacggac gtgttcagat taccgcctgc gcgggaaaga cgggatttca ggttgctgtt
    12781 tttgattttc tgtttttgtg ggaataacgg gactttggat gatgtgcatt tatcgggaaa
    12841 acaaaaaacc ctccgccgtc attcccgcga aagcgggaat ctagaatttt aatgctgcaa
    12901 gaatttatcg gggatgaccg aggtttgaag gtctggattc ccgcctgcgc gggaatgacg
    12961 gtttagaaat cacctgaaac gagaaaaaga accgaaaccg gacaagtcgg attcccgcac
    13021 gggcgggaag gacggaattt cagattgttg tttttgattt tctgttttgt gggaataacg
    13081 ggattttgga tgatgtgcat ttatcgggaa aactaaaaac cctccgccgt cattcccgtg
    13141 aaagcgggaa tctagaattt caatgccgca agaatttatc ggggatgtcc ggggtttaaa
    13201 ggtctggatt cccgcctgca cgggaatgac ggtttagaaa tcacctgaaa cgagaaaaag
    13261 aaccgaaacc agataagtcg gattcccgca cgggagggaa ggacgggatt tcaggttact
    13321 gtttttgatt ttctgttttg tgggaataac gggattttgg atgatgtgca ttttcgggaa
    13381 aactaaaaac cctccgccgt cattcccgcg aaagcgggaa tctagaattt taatgcggca
    13441 aaaatttatc ggaaaaaacc gaagtttaaa gacctagatt cccgcctgcg cgggaatgac
    13501 ggtttagaaa tcacccgaaa cgagaaaaag aaccgaaacc gaacaagccg gattaccgcc
    13561 tgcgcgggaa tgacggctca aaagttacga aacgaaaaat aaccgaaacc agacaagtcg
    13621 gattcccgcg cgggcgggaa tgacgataag cgtaatttca atctgccata ttgtcttttc
    13681 acttgcctga aaacagattt cagccgccta tccctgcatc cggcggctga tgtagtcggc
    13741 aatcaaatcc cgcttttccc aaaaaaattt ctgcattttt tgttcggaat acagtttgcg
    13801 gaccagagtg ggcagaccgc tgtggacgat ggcggcgatt tctttgttgc cttcttcttc
    13861 ctgcattgcc gtctgaaaat ccatgcccct gcctttcaga tatgctgcaa ggcggttgcg
    13921 gacatgcgaa ttgagttcga tagatttgag catttttcct ccgttttcga taacgattat
    13981 atttaatccg tctgtatgcc ttattttatc atgtttcacg atcggtttgc ctgtacaata
    14041 ccgcttttca gtatgatgtg ctggcattta tgtattcttg gttcaagctg tttcacttgt
    14101 tttttgtcat ttcgtggttt gcagggctgt tttacctgcc gaggattttc gtcaatatgg
    14161 cgatgattga tgcgccgcgc ggcaatcccg agtatgtgcg cctgtcggat atggcggtgc
    14221 ggctgtaccg ttttatgtcg ccgttgggct tcggcgcggt cgtgttcggc gcggcgatac
    14281 cgtttgccgc cggctggtgg ggcagcggct gggtacacgt caaactgtgt ttgggcttga
    14341 tactcttggc ttaccagttg tattgcggcg tgctgctgcg ccgttttcag gattacagca
    14401 atgctttttc acaccgctgg taccgcgtgt tcaacgaaat ccccgtgctg ctgatggttg
    14461 ccgcgctgta tctggtcgtg ttcaaaccgt tttgacggag catcttatgc cgatagaaat
    14521 cgaacgccgt tttttgattg gaaacgacaa ctggcggcaa tacgccgacg aaccgctgct
    14581 gttgaggcag ggttatctgt ctgttgaaaa agaacgcacc gtccgtgtcc gcattgccgg
    14641 acaacgggcg tggctgacgc tgaaaggcta tatttcggaa atcagccgca gtgagtttga
    14701 atacgaaatc ccgcttgccg atgcggaaaa gatgatggaa acgatgtgcc cgtttaaaat
    14761 ggaaaaatgg cgttatccgg tcagatgggg cggcagcctg tttgaaatcg atgttttcct
    14821 tggcgaaaac gcgcctttgg tcgtcgcgga aatcgagttg cccgacgaga atgccgattt
    14881 tgaccgtccg gactggctgg ggcgcgaaat cactgccgac ggtatgttta ccaatgctta
    14941 tttgagcagg catccgttct caagctggaa aaatgccgtc tgaaacggct tcagacggca
    15001 ttctccgaca accatcgcaa atccaaagac agcctctata tccttatttc tgctttcttt
    15061 gttccattat tcccaataaa tccccataac ctaaaatctc gtcattcccg cgcaggcggg
    15121 aatccggttc tttaaacttc ggttttttcc gataaattgc tttagctttt cgtttccgga
    15181 ttcccgcttt tgcgggaatg acgatggaag attgttgtta tttcggataa attaccctaa
    15241 ctttaaaatc ccggattccc atcttcgggg gaataacaat attttctatt tcagcccatc
    15301 atttgcgggg gattttatag agagtttata tttcaatatc tcaaataatg cacaaaagca
    15361 tagcgcgtgc ctttgctgct gacgcggcgt tccgtccgcc ctgcctcttt ccaatgcgtc
    15421 cggtctattt cggggaaaaa cgcatctcct tccacagaca aatccacttc ggttatccgc
    15481 aaatcggtcg ccaatggcat cgcttgtccg tatatctgcg cgccgcccat aatgacggct
    15541 tcttccgcgc ctgcgcacaa tgccaatgcc gcctccaaac ttgccgccgt ttccgcgcct
    15601 gccgcgcaat aatccgcctg ccggctgatg acgatgttcc tccgtccggg caggggtttg
    15661 acgggcaggg attcccacgt tttccgcccc ataatgacgg gtttgcccaa ggtataggct
    15721 ttgaaaaatg cgaaatcttc ggggatgtgc caaggcatag cattgcccgc cccgatgcac
    15781 aggttttccg cacacgccgc aattagggtt attttgagca tatttcctcc acaaaaatgc
    15841 cgtctgaacg cttcagacgg cattttatga cattccgtgt caaaaatctc aaccggcgcg
    15901 cgccatacgt tttttgtttg cacctgccaa caatgccaac agttcttcag tcgcgcccca
    15961 accgatacac gcatcggtaa tgcttttgcc gtacacttcc ggcttatcct gtctgccttc
    16021 gaccaaatgg ctttccacca tcacgcccat aatattgctc ccgtcctgtt ccaattgggc
    16081 agcaatatct tgtgccactt ccatctgccg ggtgtaatcc ttgcggctgt tggcgtggct
    16141 gcaatctatc atcagcttat cggttacccc tgccgcacgc agttgttccg ccgcctcgct
    16201 gacgtgtccc gcatcataat tcggctcttt tccgccgcgc aaaatgacat gacagtcggg
    16261 attgccgccg gtatggacaa tggcggaatg tccggccttg gttacagaca agaaatgatg
    16321 cgaatggctc gccgcaccga ttgcgtcgat ggcaatcttc aaattgccgt ccgtaccgtt
    16381 tttaaagccg acggggcagg acagcccgct tgccaattcg cggtgaactt ggctttcggt
    16441 cgtccgcgca ccgattgccc cccaagaaat caagtccgca taatattgcg gcgtaatcat
    16501 atccaaaaac tcggtagagg caggcatacc catattgttc agcgacaaca acaggctgcg
    16561 cgcctgacgc aaaccgaaat tgatatcgaa cgtaccgtcc aaatgcgggt cgttaatcaa
    16621 acctttccaa cccaccgtcg tcctcggctt ctcgaaataa acgcgcatca caatcaaaag
    16681 ctcgttttca tactgcttgc ggagtttcaa caaacgctcc gcatattcca acgccgcttt
    16741 cggatcgtga atcgaacacg gcccgataat aaccaacagc cgcttgtccc tgccgtgaac
    16801 caaatcggaa atttcctgac gggtgcggtg aaccaagccc gaagcctctt tggaaatcgg
    16861 cagctcgtaa agatgggcaa tcggcggcaa caactcttta acttctttaa tcttaatatc
    16921 gtctgtgggg taatggtgtg tcatcttgca tctttcctga tggtttttta tacgcggctt
    16981 aggttacatc gtttaccttg cacaaacaag tgcaacatat tactacaaag ctattttatt
    17041 tcaaaataac tgatatatct tttttcatag attttaaatt tcatattttt aatattttag
    17101 gaattttatt ccaaagaaaa agaaacagat tgataaaaac aatacccgcc attcattcgg
    17161 acaaaaccgc acggaacatc cgttttccca tttccacgac aatccggtac agaacacccc
    17221 gctgccgatt ccgcctgcac atccggcaaa atttcataca caaggaaaat gttgaaaaca
    17281 aaaagaactc attgcttgaa aaaagattta atgggaatgc gggtatttcc cacacttttt
    17341 ccatttattt atcctcatta taggaagaaa aacatgaaaa aaccctgctt gcactctcac
    17401 ttgcagccgt gtccgccgtt acggtagccg atattcccga gtctaacggc aaaggcaaag
    17461 ccatcatcgg cgataaggaa aaacaccgtt accaagcatg aaaaccttgc tttgaaagtc
    17521 catggcgaaa tccgccaaga tttgggggac ggatgatccc taaccccttg ggcggatgca
    17581 tatgcagatt tgcgcggcaa aaccaaagtg atgacgaccc agatgtgtgc ttcccgcgat
    17641 gtcagcaaaa gcgccaaagg ttggagtgtc ggtatcggtc tgaatgtagg caaacagttg
    17701 accgacagcg tcggtctcga gtttgatcca tactaccgtc acaaaacaat ctgcaaaccc
    17761 cgtgagattg ttttggacgg cgacaaaacc aaaatgggcc gctccaaatc caacgagtac
    17821 ggcttccgcg tagccgcaac gttctatagt caattaaaat caaaatagga cagtagtgca
    17881 tcgtcaaatc g
//
LOCUS       DAXISH010000045        17817 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.045, whole genome shotgun sequence.
ACCESSION   DAXISH010000045 DAXISH010000000
VERSION     DAXISH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 17817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17817
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.045"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..232
                     /locus_tag="ACFOV4_001476"
     CDS             <1..232
                     /locus_tag="ACFOV4_001476"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619456.1"
                     /translation="EGGSLSSLPSDGISNAAFAPYAGGSPPSFRCLRRMPVASGKPCA
                     GWLCRLKQYEGMRFRRHPPVAEIPSASCPIIA"
     gene            complement(222..1415)
                     /locus_tag="ACFOV4_001477"
     CDS             complement(222..1415)
                     /locus_tag="ACFOV4_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFC7619457.1"
                     /translation="MNPKHLIAFSALFAATQAEALPVASVSLDTVTVSPSAPYTDTNG
                     LLTDYGNAAASPWMKKIRSVAQGSGETFRILQIGDSHTAGDFFTDSLRKRLQKTWGDG
                     GIGWVYPANVKGQRMAAVRHNGNWQSLTSRNNSGDFPLGGILAHTGSGGSMTLTASDG
                     KTGKQRISLFAKPLLAEQTLTVNGNTVSANGGGWQVLDTRAALPLTIQTEMPWDIGFI
                     NIENPAGGITVSAMGINGAQLTHWSKWRADRMNDLAQTGADLVILSYGTNEAFGDNID
                     IADTEQKWLDTVRQIRDSLPAAGILIIGAPESLKNTLGVCGTRPVRLTEVQQIQRRVA
                     RQGQTMFWSWQNAMGGICSMKNWLNQGWAAKDGVHFSAKGYRRAAEMLADSLEELVRA
                     AAIRQ"
     gene            complement(1412..2395)
                     /gene="patB"
                     /locus_tag="ACFOV4_001478"
     CDS             complement(1412..2395)
                     /gene="patB"
                     /locus_tag="ACFOV4_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan O-acetyltransferase PatB"
                     /protein_id="HFC7619458.1"
                     /translation="MKNFLSLFASILMSALIAVWFSQNPINAYWQQTYHRNSPLEPLA
                     AYGWWRSGVALQENAYALSDGIKAFLSGETPPTAQDGGSADMPSEAAASEAVPQTGET
                     EWKQDTEAAAVRSGDKVFFAGDSLMQGVAPFVQKSLKQQYGIESVNLSKQSTGLSYPS
                     FFDWPKTIEETLKKHPEISVLAVFLGPNDPWDFPVGKRYLKFASDEWAQEYLKRVDRI
                     LEAAHTHRVQVVWLGIPYMKKAKLDGQMRYLDKLLSEHLEGKIILIPTAHTLSGGEDR
                     YTDSVNVNGKPVRYRSKDGIHFTAEGQKLLAAKIMEKIVFEPSTQPSSTQP"
     gene            complement(2406..3842)
                     /locus_tag="ACFOV4_001479"
     CDS             complement(2406..3842)
                     /locus_tag="ACFOV4_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HFC7619459.1"
                     /translation="MPLLSVEFALFFLAFLPIYWGLAKYPSVQNLLLLAAGMGWLYHI
                     GPVFAAIVVLYSSCVYLLGELLRSDRENTRRFWLGCGIAVSLTVLGFFKYFDFFRPLI
                     AQYAGKGGAIDILMPLGLSYYTFQSLAYLVYCFRAPHAARFSWHELLLHLSFFPTVTS
                     GPIIRAAAFKSADGEQAGALAQIRTRQPRSPVRPALAVSLILLGIAKKWWLAGMLAEN
                     WVSPVFENPAQFDGWGVLGGVYGYTFQLFLDFSGYSDLVIGMAMLLGFRLPKNFSAPL
                     RALNIRAFWDKWHISLSTWIRDYIYIPLGGSKKGFLRTQLNLMAAMVLSGIWHGYGWN
                     FLIWGALHGTALVLLNTGDRYFGRDALCRLKYLAPLSWFVTFHFVCLSFVVFNTANPD
                     DAGAVFSALFANASGWNAPQQADMLLLASFASVMLLYPYLQRAFDGVVKGLEKIPMWL
                     WFIPVSAVLLLIIVLAPSGIPGFIYANF"
     gene            complement(3970..4125)
                     /locus_tag="ACFOV4_001480"
                     /pseudo
     CDS             complement(3970..4125)
                     /locus_tag="ACFOV4_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
     gene            4471..4683
                     /locus_tag="ACFOV4_001481"
     CDS             4471..4683
                     /locus_tag="ACFOV4_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFC7619460.1"
                     /translation="METLILDIGGMSCGGCVKSVTRILEGVKGVASVEVSLENKSATV
                     GYDPAQTDAGALIEAVEDGGYDAALK"
     gene            4831..6414
                     /locus_tag="ACFOV4_001482"
     CDS             4831..6414
                     /locus_tag="ACFOV4_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase regulatory domain-containing
                     protein"
                     /protein_id="HFC7619461.1"
                     /translation="MSSKKKKAAFARAATENGVPDVSNIKNSYDDLMYESGAFSQTAI
                     NNLEARARLMGLQPAPAANAKVLELGCSMGGNIITQALYYPDAEFVGIDLSGRQVAQG
                     NAIIERMGLENVRLEEKDILTIDESFGKFDYIIVHGIWSWVPDAVKDKIFSICRNNLT
                     EHGIAYISYNVYPGWKRQEQLREIMYFAGRDVLEEPLEARTRKGLDALKALAEILEND
                     KGLDGGGKLPAIQKILNHNFYYIAHEYMEAFNDPIYVNGFIEWANRHRLAYIGDTDLH
                     VSFVSWMAEHTRERILSLAGGDYIAKEFYSDILSDRQFRRSLLCREEVGDTIRRDESV
                     AVEVIESLNFRPARGETIDFDENDTLLSGIRDVMKTGEAFKTEDVAENLARRFPGLEF
                     DRMKINSQLLLQTILGRFSVSSDNAGKPFFEDHKTYVPARFTDYAAAFVEHGAEAFVQ
                     PANRYNESTPSFGYGHLYIMRQLSRPTSKQALIETVAENLNIVSTTPDGLTFHPPAEV
                     YVEEILADLADRHFLVSAD"
     gene            6496..7593
                     /locus_tag="ACFOV4_001483"
     CDS             6496..7593
                     /locus_tag="ACFOV4_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFC7619462.1"
                     /translation="MNQTFTLPDTRPYPQNPIKNHLLLNAYQLAHNSSQASRKLSSGQ
                     LQTEIRGMLEQNHYINLSLALTMSPDAGTYAALLSSVNAVLDCEKEGEVQWFALPVVL
                     VSGCKKERAIEMKLPTEALFACLQNYPHLRALTQETQWLPYLVHSSDLSAVAPDEWWR
                     AKQNTEAAAQHLRRFAPRPLLLPEGQSVHVVYALGFGSGKVQTGLGQNLLQAGLPLMQ
                     VWQENLASEGVTLFANPLSPDSPVRALSDGSHTRQRMAMDVFAANTIRAVRMQSPRVG
                     VVAAAKAGGQVLFGFNATDGAFEVVPQVFSWQLSFTDNIGVIQQNFLDLMAECRVEHV
                     YLLHNPLGEQENIPSYAEALKREGHNPFFSA"
     gene            7707..8822
                     /locus_tag="ACFOV4_001484"
     CDS             7707..8822
                     /locus_tag="ACFOV4_001484"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFC7619463.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLEEKCLQVTGPFGQKEVMRYFQKEQLALFEVADLVGLGKIPLEKR
                     NPLQIQTRGIGELIRHLISQEIKEIYIGVGGTASNDGGIGIAAGLGYQFYDEDGNTLP
                     ACGQSLLNLASVSTENRYEIPEDVHIRILADVVSPLCGHQGATYTFGKQKGLDSTMFE
                     AVDQAIQDFYEKVSPATLKLKGAGAGGGIAGGLCAFAQASIVSGIDTCLDLIDFDKKV
                     SDVDLVIIGEGRLDRQSLAGKAPIGVAKRTPVGVPVVAICGSLVEDLPSLPFENIQAA
                     FSILEKSEPLEDSLKNASLYLEHTASNIGHLLNMPKI"
     gene            8947..9402
                     /locus_tag="ACFOV4_001485"
     CDS             8947..9402
                     /locus_tag="ACFOV4_001485"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFC7619464.1"
                     /translation="MKKPKILFVCLGNICRSPMAEYILRRRAAEAGIPLEADSAGTSG
                     WHDGEDMHRETAKILKKHGIDASGFTSRKIRQSDAAAFDCIIAMDGKNLSELERTFGR
                     RSEKIFKLTDLIPESGYDHVPDPWYTGDFEETFRLADAGCRALLEKISK"
     gene            9473..9949
                     /locus_tag="ACFOV4_001486"
     CDS             9473..9949
                     /locus_tag="ACFOV4_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFC7619465.1"
                     /translation="MKTNFKQKIIEQARSEGLQVTALREQVLDIVLQQSGVIKAYNVL
                     SQMQQQSEGVLAPPTAYRALDFWAEQGVLHKVAAVNGYILCSHAQHECDDHCHDHEEA
                     EAHHSAFILVCTECGTADEQTLSHEWAALRAGVAESGFALKEEHVVLTGICKKCQK"
     gene            9937..10863
                     /locus_tag="ACFOV4_001487"
     CDS             9937..10863
                     /locus_tag="ACFOV4_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFC7619466.1"
                     /translation="MSEMKKTKVHLISGFLGTGKTTALKSLMEQKDPNEKWVIIVNEF
                     GEIGIDGAVLSDNGIPVAEIAGGCLCCTAGPQMGVTVQKMLRDAKPDRLMIEASGLAH
                     AASVIDELKAKPLDSLLEIGAVFTVVDPRQFINPDYAQQALYKDQIGICDVLAASKTD
                     LCTPEQLVEFHDKAAKLFPPKAKVVEVRNAQLDIQWLDIPVIEKSRYRLKALPDNTMG
                     FQSQGFTFPAGRDFDGEKLTNFFNDLPKMTEGLVRAKGVFQVLGTWVWLNWVDGQWGA
                     NQVSWRRDSRFELIAKSFDADLIEQKLKDALE"
     gene            10928..11482
                     /locus_tag="ACFOV4_001488"
     CDS             10928..11482
                     /locus_tag="ACFOV4_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC7619467.1"
                     /translation="MKPKFKTVLTALLLAVSLPSMAATHVLMETDMGNIRLVLDESKA
                     PKTVANFVRYARKGFYDNTIFHRVIGGFVIQGGGLTEDLAQKASDKAVANESGNGLKN
                     TVGTIAMARTTDPDSATSQFFINLADNDSLNYKNGQYGYTVFGRVESGMDTVSKIARV
                     KTATRGFYQNVPVQPVKIRRVVVE"
     gene            complement(11721..12680)
                     /gene="ttcA"
                     /locus_tag="ACFOV4_001489"
     CDS             complement(11721..12680)
                     /gene="ttcA"
                     /locus_tag="ACFOV4_001489"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HFC7619468.1"
                     /translation="MSKKIKQELENNKLSKRLRHAVGDAINDFNMIEPGDKIMVCLSG
                     GKDSYALLDILRRLQASAPIDFQLVAVNLDQKQPGFPEEVLPTYLESIGVPYKIVEED
                     TYSTVKRVLDEGKTTCSLCSRLRRGILYRTAKELGCTKIALGHHRDDILATLFLNMFY
                     GGKLKAMPPKLVSDNGEHIVIRPLAYVKEKDLIKYAELKQFPIIPCNLCGSQPNLQRQ
                     VIGDMLRDWDKRFPGRIESMFSALQNVVPSHLADTELFDFVGLERGQSLKHGGDLAFD
                     SEKMPERFSDGSEEDESEIKIEPQKAERKVINILANKPKTCGA"
     gene            complement(12773..13636)
                     /locus_tag="ACFOV4_001490"
     CDS             complement(12773..13636)
                     /locus_tag="ACFOV4_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate-binding protein YgfZ"
                     /protein_id="HFC7619469.1"
                     /translation="MKTLLPFFGVVRVSGEDRQTFLHGQLSNDINNLQTGQACYATYN
                     TPKGRVIANMIVVNRGGDLLLIMAQDLLEATVKRLRMFVLRAKVVFEILEDYAVGAEL
                     EASAEPLAAQEPSLVFTAECVSDGICSVVLPHRGILHIAPETALPPYDAAAENAWRLH
                     EIRSGYPWICAATKETAVAQMLNQHIIGGVHFKKGCYPGQEIIARAQYRGQVKRGLAV
                     LSGNSAVEAGTLLTADGEEAGIVLDSVQDSENFTALTVIKFSAAQKELTVPNGGIFKA
                     VHLFFKTENAE"
     gene            complement(13671..14033)
                     /locus_tag="ACFOV4_001491"
     CDS             complement(13671..14033)
                     /locus_tag="ACFOV4_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFC7619470.1"
                     /translation="MDIRYFGTTPRYSEAVGANGLIFLSGMVPENGETAAEQTADVLA
                     QIDRWLAECGSDKAHVLDAVIYLRDMGDYAEMNGVWDAWVAAGRTPARACVEARLARP
                     EWRVEIKITAVKRDAATA"
     gene            14108..14587
                     /gene="ybaK"
                     /locus_tag="ACFOV4_001492"
     CDS             14108..14587
                     /gene="ybaK"
                     /locus_tag="ACFOV4_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFC7619471.1"
                     /translation="MSKHTYPITPAVRVLRENGIEFEPFTYAYEEHGGTAQFARLFGK
                     DEHLVIKTIVLQDENGNGLIVLMHGDKQISTRNLARHLGAKRIEPATPAQANKWTGYL
                     VGGTTPFGIRTKLDIYVEQSVMDLETIYINGGKRGFIIGIRPGDLNILNPKTIQAAV"
     gene            14609..15331
                     /locus_tag="ACFOV4_001493"
     CDS             14609..15331
                     /locus_tag="ACFOV4_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFC7619472.1"
                     /translation="MDKDLYAVLGVSPQAGADEIKRAYRKLAMKYHPDRNPGNPQAEE
                     KFKEIQRAYDTLSDLSKRMQYDASFRRHEERGRQEEAFRREQARREQFYREQMRREQA
                     FRQAFERQASRSCHTYEPSGGGSGRNYVLAAYILFGLGAIMLFMPIVGVIFAYMPIVG
                     VILAYMKRNSLDSIVYAAHTEYLIKTFWRTFWLYILGALTALLGIGVLIIIATNVWYF
                     YRIIAGFIRFNGGRAVAPEKWI"
     gene            15333..16208
                     /locus_tag="ACFOV4_001494"
     CDS             15333..16208
                     /locus_tag="ACFOV4_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA/RhaT family transporter"
                     /protein_id="HFC7619473.1"
                     /translation="MAYLLISIVFSVSVSILLKMARKKKIDIAQAVAVNYVVAVILTL
                     LVLKPDVGNIGAFLPTWWLFAALGVLLPSVFVIMGKSVESAGIVKSDAAQRLSLFLPI
                     VAALTLFGEKLSEGRLIGLCLAFAALFCLLWKHSGGKKSGSAWRQAALLLGVWAGYGI
                     IDILFKQLAKSGTAFAGNLLVAFVLAGVLMFACLFAKSVRWRVESVVGGIFLGGLNFM
                     NIVTYITAHQMMKDNPTLVFAGMNIGVIVLGTLSGALFFKEKINTINTAGIVLALCSI
                     ACLFYWGEVKVLFGI"
     gene            complement(16280..17677)
                     /gene="aspA"
                     /locus_tag="ACFOV4_001495"
     CDS             complement(16280..17677)
                     /gene="aspA"
                     /locus_tag="ACFOV4_001495"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008797 - aspartate ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HFC7619474.1"
                     /translation="MTVRIEHDLLGDREIPAEVYWGIHTLRAIENFKISTQKISDVPQ
                     FVRSMVMVKKATAQANGKLGAVKPEIAAAIEKACDEVLLNNRCLDQFPSDVYQGGAGT
                     SVNMNTNEVIANLALEVLGYEKGRYDIVNPMVHVNASQSTNDAYPTGFRLAVYYSIGE
                     LLDKLAVLKNAFAAKAEEFKDVLKMGRTQLQDAVPMTAGQEFQSFQVLLEEEILNLDR
                     TRQLLLEVNLGATAIGTGVNTPKGYAELVVKKLSEVSGLPCKLTENLIEATSDCGAYV
                     MVHGALKRTAVKLSKICNDLRLLSSGPRAGLKEINLPELQAGSSIMPAKVNPVIPEVV
                     NQVCFKVIGNDTTITFAAEAGQLQLNVMEPVIAQCMFETISLLGNAAVNLSDKCVKGI
                     TVNREICERYVFNSIGLVTYLNPYIGHHNGDLVGKICAQTGKGVREVVLERGLLSEEE
                     LNRILSPENLMNPHL"
BASE COUNT         4126 a         4388 c         5103 g         4200 t
ORIGIN      
        1 ggaaggcggc agtttatcat ctttgccttc agacggcata tcaaacgccg cctttgcgcc
       61 gtatgccgga ggttcgcccc cgtccttccg atgcttgagg cgaatgccgg ttgcgtccgg
      121 caaaccgtgc gcggggtggc tatgccgtct gaagcaatat gaaggtatgc gtttcagacg
      181 gcatccccct gttgcggaaa taccgtccgc ctcctgtccg attattgcct gattgcagcg
      241 gcgcggacga gttcttcgag gctgtcggcg agcatttccg ccgcgcgccg gtagcctttg
      301 gcggagaagt gtacgccgtc tttggcggcc catccttggt tgagccagtt tttcatgctg
      361 catatgccgc ccatggcgtt ttgccaagac cagaacatgg tttgtccctg ccgggcgacg
      421 cgccgctgta tctgttggac ttcggtcagg cggacggggc gtgtgccgca tacgccgagc
      481 gtgtttttca gggattcggg tgcgccgatg atgaggatgc cggcggcagg caggctgtcg
      541 cggatttggc ggacggtatc cagccatttt tgttcggtgt cggcaatgtc gatgttgtcg
      601 ccgaaggctt cgttggtgcc gtaggaaagg ataaccaaat cggcgccggt ttgggcaagg
      661 tcgttcatac ggtcggcacg ccatttcgac caatgggtca attgtgcgcc gttgatgccc
      721 atggcggaaa cggtaatgcc gccggcggga ttttcgatgt tgatgaagcc gatgtcccac
      781 ggcatttcgg tctgtatggt caagggcagt gccgcgcggg tatccagtac ctgccagccg
      841 ccgccgttgg cggagacggt gttgccgttg acggtcaggg tttgttcggc gagcaggggt
      901 ttggcaaaca gggaaatgcg ctgtttgccg gtcttgccgt ccgatgcggt cagggtcatg
      961 ctgccgccgc tgccggtgtg ggcgaggatg ccgccgagcg ggaagtctcc gctattgttc
     1021 ctgctggtga ggctttgcca gttgccgttg tgccggactg ccgccatgcg ctgccctttg
     1081 acgttggcgg ggtaaaccca gcctatgccg ccgtcgcccc aagttttttg caggcgtttg
     1141 cgcaggctgt cggtaaagaa gtcgccggcg gtatgcgagt cgccgatttg caggatgcgg
     1201 aaggtctcgc cgctgccttg tgcgacggat cggatttttt tcatccaagg cgaggcggcg
     1261 gcgttgccgt agtcggtcaa gagcccgttt gtatcggtgt agggggcgga cggggaaacg
     1321 gtaacggtgt cgaggctgac ggaggcgacg ggcagggctt ctgcctgcgt ggcggcgaac
     1381 agggcggaaa atgcgatgag gtgtttgggg ttcatggctg tgtacttgat ggttgcgtac
     1441 ttggttcaaa aacgattttt tccattattt ttgccgccag cagtttttgt ccttcggcgg
     1501 taaagtgtat gccgtccttg ctgcggtagc ggacgggttt gccgttgacg ttgacggagt
     1561 cggtgtagcg gtcttccccg ccgctcaggg tgtgcgcggt gggaatcagg atgattttgc
     1621 cttccaggtg ttccgaaagc agtttgtcga ggtagcgcat ctgcccgtcg agcttggctt
     1681 ttttcatata ggggatgccg agccagacga cttggacgcg gtgcgtgtgt gcggcttcaa
     1741 ggatgcggtc gacgcgtttc aggtattctt gcgcccattc gtcggaagcg aatttgaggt
     1801 atcgtttgcc gacggggaaa tcccacgggt cgttcgggcc gaggaagacg gcgagcacgc
     1861 tgatttcggg atgttttttc agggtttctt caatcgtttt cggccagtcg aagaatgagg
     1921 ggtaggacag ccccgtgctt tgtttgctga ggttgacgga ttcgatgccg tattgctgtt
     1981 tcaggctttt ttgcacgaag ggtgcaacgc cctgcatcag cgagtcgccg gcaaaaaaga
     2041 ctttgtcgcc gctgcggacg gcggcggctt cggtgtcttg tttccattct gtttcaccgg
     2101 tttgagggac ggcttctgat gcggcggctt cagacggcat atctgccgaa ccgccgtctt
     2161 gagccgtcgg cggcgtttcg ccggacagga aggctttgat gccgtctgaa agggcgtagg
     2221 cgttttcttg caacgccaca ccgctccgcc accatccgta ggcggcgagc ggttcgagcg
     2281 ggctgttgcg gtggtaggtc tgctgccagt aggcgttgat ggggttttgg ctgaaccaca
     2341 cggcaatcag ggcagacatc aatatggagg cgaaaaggga aagaaagttt ttcatgtcca
     2401 aacccttaaa aattggcata aataaagccg ggtatccccg agggggcgag gacgataatc
     2461 agcagcagga cggcggaaac ggggataaac cacagccaca tcgggatttt ttccaaacct
     2521 ttgaccacgc cgtcgaaagc gcgttgcagg taagggtaga gcagcatcac ggatgcaaac
     2581 gaggcaagca gcagcatgtc tgcctgttgc ggcgcattcc agccgctggc attggcaaag
     2641 agcgcgctga aaaccgcgcc ggcatcgtcg gggtttgcgg tattgaagac gacaaagcta
     2701 aggcagacaa aatggaaggt aacaaaccac gagagcggcg caaggtattt cagacggcat
     2761 agcgcgtcgc gtccgaaata acggtcgccc gtgttgagca gcaccagcgc cgtgccgtgc
     2821 agcgcgcccc aaatgaggaa gttccagccg tagccgtgcc atatgccgga gagtaccatt
     2881 gccgccatca ggttgagctg tgtccgtaaa aagccttttt tgctgccgcc caaggggatg
     2941 tagatgtagt cgcgtatcca ggtggaaagg ctgatgtgcc atttgtccca aaatgcgcgg
     3001 atgtttaaag cacgaagcgg tgcggagaag tttttgggca gccggaaacc cagcagcatc
     3061 gccatgccga taaccaaatc ggaatatccg gaaaagtcta aaaagagttg gaaggtatag
     3121 ccgtacacgc cgcccaatac gccccagccg tcgaattggg cgggattttc aaatacgggc
     3181 gacacccagt tttccgccag catccccgcc agccaccatt ttttggcaat acccagcaga
     3241 atcagggaaa cggcgagtgc ggggcggacg ggtgagcgcg gttggcgggt acggatttgc
     3301 gccaatgcgc ccgcctgctc gccgtccgcg cttttgaatg cggcggcgcg gataatcggg
     3361 ccagaggtaa cggtgggaaa gaaactcagg tgtagtagca gctcgtgcca gctgaaacgc
     3421 gcagcgtgcg gggcgcggaa gcagtaaacc agataggcga gcgactggaa ggtgtaatac
     3481 gaaagcccca gcggcatcag gatgtcgatt gcgccgcctt ttccggcata ttgggcaatc
     3541 agcgggcgga aaaagtcgaa atatttgaaa aagcccaaga cggtcagcga gacggcaatg
     3601 ccgcacccca gccaaaagcg gcgcgtattt tcgcgatcgg aacggagcag ttcgcccaaa
     3661 aggtacacgc aggaggaata aaggacgacg attgccgcaa atacggggcc gatatggtag
     3721 agccagccca taccggcagc caaaagcagc aggttttgga cggacgggta tttcgccaag
     3781 ccccagtaaa tcggcaggaa ggcgagaaag aacagtgcga actcgacaga cagcagcggc
     3841 ataaaccatc cttggaacaa aaaataggcg ttaaaacacg gcaaagcccg ttattttaag
     3901 caggggtgga tatttcttca atcaaaatgc cgtctgaagg gcgggagagg cttcagacgg
     3961 catcgcgggt caggttcgga tatggcggtt caagttcagg cacagccaca gcccggccgc
     4021 cgccgcaagc ataccggcga tgccgatacg ggaaataccg acatattgcg ttacccaatg
     4081 tcccaacagt gcgccgctgc cgataccgac gttgtatagt ggattaacaa aaatcaggac
     4141 aaggcgacga agccgcagac agtacaaata gtacggaacc gattcacttg gtacttcagc
     4201 accttagaga atcgttctct ttgagctaag gcgaggcaac gacgtactgg tttttgttaa
     4261 tccactataa atgcgccgat tgccaaggcg atgatgctca accagggttt ttgcgaagcg
     4321 ttcattgttg tcgtcctgat gggaattgcc gccattatgc gcaagcgtcc gtctttttcc
     4381 aaaccgccgc accgtttccg cgtttgccca agttcacgcc ccgacttaca ataacgcccg
     4441 tcagattgca gttccaacga aaggaaaatg atggaaaccc ttatcctcga catcggcggc
     4501 atgagctgcg gcggctgcgt caaaagcgtt acccggatat tggaaggcgt aaaaggcgtg
     4561 gcaagcgtcg aagtcagcct tgaaaacaaa agtgcgaccg tcggatacga ccccgcgcaa
     4621 accgatgcag gggcgttgat tgaagccgtt gaagacggcg gctatgatgc cgcgttgaaa
     4681 taaagcggca aaaatgccgt ctgaagcctt cgcgcctcct agatgccgtc tgaagtacgc
     4741 tccgcgcctt cagatggcat ttgatttagt tgaacgggta ggatgaattg gttaaacttg
     4801 cgggcatatt gtctttagag tgaacaaaat atgtcgagca agaagaaaaa agccgctttt
     4861 gcccgtgctg caacggagaa cggtgtgccg gacgtgtcca acatcaaaaa ttcatatgat
     4921 gatttgatgt acgaatccgg cgcattctct caaaccgcca tcaataattt ggaggcgcgc
     4981 gcccgcctga tgggcttgca gcccgcgccc gccgccaatg ccaaggtctt ggagctgggc
     5041 tgttcgatgg gcggcaacat catcacgcag gcgctttatt acccggatgc ggaatttgtc
     5101 ggtatcgact tgtccggcag gcaggttgcg cagggcaacg ccatcattga aagaatgggc
     5161 ttggaaaatg tgcgtctgga agaaaaagat attttgacca tcgatgagtc attcgggaag
     5221 ttcgactata tcatcgtcca cggcatttgg tcgtgggtgc ctgacgcagt taaagacaaa
     5281 atcttttcga tttgccggaa caacctgacg gaacacggca ttgcctatat ttcatacaat
     5341 gtttaccccg gctggaaacg gcaggagcag ttgcgcgaaa ttatgtactt tgccggcagg
     5401 gatgtgcttg aagaaccctt ggaagcgcgg acgcggaaag gcttggacgc gctcaaggcg
     5461 ctggcggaaa ttttggaaaa cgacaagggc ttggacggcg gcggcaaact tccggcgatt
     5521 caaaaaatat tgaatcataa tttttattac atcgcacacg aatatatgga ggcgtttaac
     5581 gacccgattt acgtcaacgg cttcatcgaa tgggcaaacc gccaccggct ggcgtatatc
     5641 ggggataccg atttgcacgt gtcttttgtt tcttggatgg cggagcatac gcgggagcgg
     5701 attctgtcgt tggccggggg cgattatatt gccaaagaat tttatagcga tattttatcc
     5761 gaccgccaat tccgccgttc gcttttatgc cgtgaggaag tcggggatac tatcaggcgt
     5821 gacgagtcgg ttgccgtcga agtgatagaa agtttgaatt tccgcccggc aagaggggaa
     5881 acaatcgact ttgatgaaaa cgataccctg ctttcgggca tacgcgatgt gatgaaaacc
     5941 ggagaggcgt ttaaaacgga agatgttgcg gaaaatctcg cccgccgatt tcccggtctg
     6001 gaatttgacc gcatgaaaat caattcccag cttttattgc aaaccattct cgggcgtttt
     6061 tctgtttcat cagacaatgc gggcaaacca ttttttgaag accataaaac ctatgtgccg
     6121 gcgcgtttta cagattatgc cgccgccttt gtggaacacg gcgcggaagc gtttgtccag
     6181 cctgccaacc gttacaacga aagcaccccc tcattcgggt acgggcattt gtacattatg
     6241 cggcaattgt cgcggccgac gagcaaacag gcattgattg aaacggttgc cgaaaacttg
     6301 aacatcgtca gcaccacgcc cgacggtttg acattccatc cgcctgccga agtgtatgtg
     6361 gaagaaatat tggcagactt ggcagacagg cattttctcg tttcggcgga ttgacgggca
     6421 agtcccgacg gcaatccgtc cgatatattt tcaaacagga aaaacacaca ctacgaaaag
     6481 cggtacacga catatatgaa ccagacattt accttgcccg atacgcgccc gtatccccaa
     6541 aatccgatta agaaccacct gctgctcaat gcctaccagt tggcgcacaa ttcttcccag
     6601 gcttcgcgca aactctcgtc cggccaactt caaaccgaaa tcagggggat gcttgagcaa
     6661 aaccactata tcaacctttc cctcgcgctg acgatgtcgc ccgatgccgg aacttatgcc
     6721 gcgctgcttt ccagtgtgaa cgcagtactc gattgcgaga aagaaggcga agtgcagtgg
     6781 ttcgccctgc cggtcgtgct ggtgtccggc tgcaagaaag aacgggcaat cgagatgaag
     6841 ctgccgacgg aggcattgtt tgcctgcctg caaaactatc cgcacctgcg cgcgttgacg
     6901 caagagacac aatggctgcc ttatcttgtg cattcgtccg atttgagtgc ggtcgcgccg
     6961 gatgagtggt ggcgtgccaa acaaaatacc gaagcggcgg cgcaacactt acgccgtttc
     7021 gccccgcgcc ctttgctgtt gcccgaaggg cagtccgtcc acgtcgttta cgcgctgggt
     7081 ttcggcagcg gcaaggttca gacgggattg ggtcagaacc ttcttcaggc aggcctgccc
     7141 ttaatgcagg tatggcagga aaatcttgca tcggaaggtg ttacgctgtt tgccaatccg
     7201 ctttccccgg attctccggt acgcgcgctt tcagacggca gccacacgcg ccagcgtatg
     7261 gcgatggatg tttttgcggc aaacacgata cgcgccgtcc gtatgcagag tccgcgcgtc
     7321 ggcgtggtcg ctgcggcaaa ggcgggcgga caggttttat tcgggtttaa tgcgaccgac
     7381 ggcgcgttcg aagtcgtgcc gcaggtgttt tcgtggcagc tttcctttac cgacaatatt
     7441 ggcgttattc agcaaaattt tttggattta atggcagaat gccgtgtaga acacgtttac
     7501 ctgttgcaca atcctttggg cgaacaggaa aacatcccga gctatgcgga agcgttgaaa
     7561 cgggaagggc acaatccgtt tttcagtgca tagtgatttg tagtagtgat aggctttctc
     7621 atttctataa taaatcaaaa taaagagcac aacacttttt cattctgtgt tgtgccttga
     7681 gtgaaacgaa aggatgaatt ataaatatga agattgtaat tgcaccggat tcgtttaagg
     7741 aaagcttgac agctcaacag gtagctgaag caataaaaag aggcttccaa caatcgatag
     7801 cagatgtgga atgtctcctc tgtcctgtcg gtgatggggg agaaggcact gtagatgcta
     7861 tccgacattc tcttgaccta gaagaaaaat gtctccaagt gacaggacct tttggacaaa
     7921 aagaagtcat gcgctatttt caaaaagaac aactagccct attcgaagtt gctgatttgg
     7981 ttggtcttgg aaaaatcccg ctagagaaac gaaatccatt acaaatccaa actcgtggta
     8041 ttggagaatt gattcgccac ctcattagtc aagaaattaa agaaatctat attggcgttg
     8101 gcggtacggc cagtaatgat ggaggtattg ggattgctgc tggtttaggt tatcaatttt
     8161 atgatgagga tggaaatacc ttgcccgctt gcggtcaatc cttactaaac ctagcttctg
     8221 tttcaacaga aaatcgctat gaaattcctg aagatgttca cattcgtatt ttagcagatg
     8281 ttgtgagtcc cttatgtgga caccaaggtg cgacctatac gtttggcaag caaaaagggt
     8341 tggattctac tatgtttgag gccgtagatc aggcaataca agatttttat gaaaaagtct
     8401 cccctgcaac attaaaactt aaaggagcag gagctggtgg aggcatcgct ggtggtttgt
     8461 gcgcctttgc tcaggcaagt atcgtatctg gaattgacac ctgcctggac ttgattgact
     8521 ttgataagaa agtgtcagat gttgacttgg ttatcattgg tgaaggaaga ctagatcgtc
     8581 aaagtttagc agggaaagcg cctattggtg tagcaaaaag aacccctgtc ggagttcctg
     8641 ttgtcgctat ttgtggcagt ctcgttgaag atttgccttc cctgccattt gaaaatatcc
     8701 aagctgcctt ttctattttg gagaaaagtg aacctttaga agatagtttg aaaaatgcca
     8761 gtctctattt ggagcatacg gcttctaata ttggacactt attaaatatg cctaagattt
     8821 agccaaacca tttcttccag atggatgttt tggctggttc tgccttatgc ggttacgatt
     8881 aaccgaccga tgacgtctga aagggtttcc gcttcagacg gcatcgcgcc ggaacaggga
     8941 ggggatatga aaaaaccgaa aatccttttt gtctgcctcg gcaacatctg ccgttcgccg
     9001 atggcggaat acattttgcg ccgccgcgcc gccgaagcgg gcattcccct tgaagcggac
     9061 agcgcgggga catcgggctg gcacgacggc gaagatatgc accgcgagac ggcaaagata
     9121 ttgaaaaaac acggtatcga tgcttcaggc tttaccagcc gcaaaatccg ccaaagcgat
     9181 gcggcggcgt ttgactgcat catcgcgatg gacggcaaga atttgtccga attggaaaga
     9241 accttcggca ggcggtcgga aaaaatattc aagctgaccg acctgatacc cgaaagcggt
     9301 tacgaccatg tccccgatcc gtggtacacg ggcgattttg aagaaacctt caggcttgcg
     9361 gatgcgggct gtcgggcatt gttggaaaag atttccaaat aaagcaattg aatacaaata
     9421 taaaaccgcc tcctgccgta tcggttgttc agacggcata aacagagaat ttatgaaaac
     9481 aaatttcaaa cagaaaatta ttgaacaggc acgcagcgaa ggcttgcagg taaccgcttt
     9541 gcgcgagcag gtattagata ttgtcttgca gcaaagcggc gtgattaaag cctacaacgt
     9601 cttgtcgcag atgcagcagc aaagcgaggg cgtgcttgca ccgcctaccg cctaccgcgc
     9661 ccttgatttt tgggcggagc agggcgtttt gcacaaagtg gcggcggtca acggctatat
     9721 tttgtgcagc cacgcgcagc acgagtgcga cgaccattgc cacgaccacg aagaagccga
     9781 agcgcaccac agcgcgttta ttttggtctg caccgaatgt ggcacggcgg acgagcaaac
     9841 cctcagccac gagtgggcgg cactgcgcgc aggcgttgcc gaaagcggct ttgcgctgaa
     9901 agaagaacac gttgttttaa ccgggatttg taaaaaatgt cagaaatgaa aaaaaccaaa
     9961 gtccacctga tttcaggttt tctgggaaca ggcaaaacca ccgcgctcaa aagtctgatg
    10021 gaacaaaaag accccaacga aaaatgggtc atcatcgtca acgagtttgg cgaaatcggc
    10081 attgacggcg cggtattgag cgacaacggc atccctgtgg cagaaatcgc cggcggctgt
    10141 ttgtgttgca ccgccggccc gcaaatgggc gtaaccgtgc agaaaatgct gcgcgatgcc
    10201 aagcccgacc gcctgatgat tgaggcaagc ggactggcgc acgccgccag cgtcatcgac
    10261 gaactcaaag ccaaaccgct ggacagcctt ttggaaatcg gcgcggtctt taccgtcgtc
    10321 gatccgcgcc aattcatcaa ccccgattac gcgcaacagg cattgtataa agaccaaatc
    10381 ggcatttgcg acgtattggc cgccagcaaa accgatttat gcacccccga acagctggtc
    10441 gaatttcacg acaaagcggc aaaactgttc ccgcccaaag ccaaagtggt cgaagtccga
    10501 aacgcgcaac tcgatatcca atggctcgat attcccgtca tcgaaaaatc acgctaccgc
    10561 ctcaaagccc tgccggacaa cacgatgggc ttccagtcgc aaggtttcac attccccgcc
    10621 ggacgcgatt tcgacggcga aaaattgacc aacttcttca atgatttgcc caagatgacc
    10681 gaaggactcg tccgcgccaa aggcgtgttt caagtactcg gcacttgggt gtggctcaac
    10741 tgggtggacg ggcaatgggg tgcgaaccaa gtctcgtggc ggcgcgattc gcgttttgaa
    10801 ttgattgcca aatcgtttga tgcggattta atcgaacaaa agctcaaaga cgcattggaa
    10861 tagcgttcac gcgccttcag acggcatatg aaatgaaaat gccgtctgaa ggtctgagga
    10921 ggacgggatg aaacccaaat tcaaaaccgt tttaaccgcg ctgcttttgg cggtttccct
    10981 gccgtctatg gcggcaaccc atgttttgat ggaaaccgat atgggcaata tccgtttggt
    11041 tttggacgaa tccaaagcac ccaaaaccgt tgccaatttc gtgcgctatg cccgaaaagg
    11101 cttttacgac aatacgattt ttcaccgcgt catcggcggc ttcgttatcc aaggcggcgg
    11161 attgaccgag gacttggcac aaaaggcaag cgataaggcc gttgccaacg aatccggcaa
    11221 cggcttgaaa aacactgtcg gcaccatcgc catggcgcgg acgacagacc ccgattccgc
    11281 caccagccaa ttctttatca atctggcgga caatgattca ctcaactaca aaaacggaca
    11341 atacggctat accgttttcg gcagggtcga aagcggaatg gacaccgttt ccaaaatcgc
    11401 ccgcgtcaaa accgccacgc gcggctttta tcaaaacgta cccgtacagc ccgtcaaaat
    11461 ccgtcgcgtt gttgtcgagt aatataacgg gaaaccttca gaaagctgaa acggaaaaag
    11521 caggtgtttg gggttgaaaa gcgtctgctt cgggatttta taatggatta aatttaaacc
    11581 agtacggtgt tgtctcgcct tgccgtacta tttgtactgt ctgcggcttc gtcgccttgt
    11641 cctaatttaa atttaatcca ctataaaatg ccgtctgaaa cgccaaacgg gcttcagacg
    11701 gcatttttga cggcgggggg ttacgcgccg caggttttcg gcttgttcgc cagaatgttg
    11761 atgactttgc gttcggcttt ttgcggctcg attttgattt cgctttcgtc ttcttcgctg
    11821 ccgtctgaaa aacgttcggg cattttttcg ctgtcaaacg ccaaatcgcc gccgtgtttc
    11881 aggctttgac cgcgttccaa tccgacaaag tcgaagagtt cggtatcggc aaggtgggaa
    11941 gggacgacgt tttgcagggc ggagaacatc gattcgatgc ggccggggaa gcgtttgtcc
    12001 caatcgcgca gcatatcgcc gatgacttgg cgttgcaggt tgggttgcga gccgcagagg
    12061 ttgcacggga tgatggggaa ttgttttaat tcggcgtatt tgattaagtc tttttctttt
    12121 acatacgcca gcggacggat gacgatgtgt tcgccgttgt cgctcaccag cttgggcggc
    12181 atggctttga gtttgccgcc gtaaaacata tttaaaaaca aggtggcgag gatgtcgtcg
    12241 cggtggtgtc ccaaggcgat tttggtgcag cccaattctt ttgcagtgcg gtagaggatg
    12301 ccgcggcgca ggcggctgca cagcgaacaa gtcgttttgc cttcgtctaa tacgcgtttg
    12361 acggtggagt aggtgtcttc ttcaacgatt ttgtagggaa cgccgatgct ttcgagatag
    12421 gtcggcaata cttcttcggg gaagcccggc tgcttttggt cgagattgac ggcaactagt
    12481 tggaaatcaa tcggcgcgct ggcttggagc cggcgcagga tgtccaagag ggcatagctg
    12541 tcttttccgc cggagaggca gaccatgatt ttgtcgcccg gctcgatcat attgaaatcg
    12601 ttaatcgcgt cgccgacggc gtggcgcagg cgtttgctga gtttgttgtt ttcgagttct
    12661 tgcttgattt ttttggacat aacggttcgg gtttgaaaat tggaaaggcg gcattgtaac
    12721 cgattggcgg ggcggcaatg ccgtctgaag ggcttcagac ggcatcggcg gcttattctg
    12781 cattttcggt tttaaagaag agatgaaccg ctttgaagat accgccgttt gggacggtca
    12841 gttctttttg tgcggcggag aatttaatca cggtaagggc ggtaaagttt tccgaatctt
    12901 gaacgctgtc gagtacgatg ccggcctctt cgccgtccgc cgtcagcagg gttcctgctt
    12961 cgacggccga atttcccgac aataccgcca agccgcgttt gacctgcccc cgatactggg
    13021 cacgggcaat gatttcctgt cccggatagc agcctttttt gaagtgtacg ccgccgatga
    13081 tgtgctggtt gagcatttgg gcgacggcgg tttctttggt agccgcgcat atccacgggt
    13141 aaccgctgcg gatttcgtgc agccgccacg cgttttcggc ggcggcatca taaggcggca
    13201 gggcggtttc gggggcgatg tgcaaaatgc cccgatgggg caggacgacg gaacagatgc
    13261 cgtctgaaac gcattcggcg gtaaagacga gactgggttc ttgcgcggca agcggttcgg
    13321 cggatgcttc taattccgcg ccgacggcgt aatcttcaag gatttcaaaa acgactttgg
    13381 cacgcaacac aaacatccgc aggcgtttga cggttgcttc aagcaggtct tgcgccataa
    13441 tcagcagcaa atcgccgcct cggttgacga caatcatatt ggcgatgacg cggcctttgg
    13501 gcgtgttgta agtcgcataa cacgcctgcc cggtctgaag attattgatg tcgttggaaa
    13561 gctgtccgtg caggaaggtt tggcggtctt cgccactgac gcgcaccacg ccgaaaaagg
    13621 gcagtaaggt tttcatcatt tgcctactct gaaaatataa ggaaatctgt ttatgcagtt
    13681 gccgcgtctc tcttcacggc ggttattttg atttcgacgc gccactccgg acgggcgagc
    13741 cgcgcttcca cgcaggcgcg ggcgggcgtt ctgccggcgg caacccaagc gtcccacacg
    13801 ccgttcattt ccgcatagtc gcccatatcg cgcagataga tgaccgcatc caaaacgtgc
    13861 gctttgtccg agccgcattc cgccagccag cggtcgattt gggcaagcac gtcggcagtc
    13921 tgttcggcag ccgtttcacc gttttcggga accatgccag agaggaaaat caagccgttt
    13981 gcgccgacgg cttcggaata gcggggcgtt gtgccgaaat atcggatatc catatcggtt
    14041 tccttcgata aaggggatat atggtaacat tgcgcttgac cgatttccat gttttgcatg
    14101 acgaaaaatg agtaaacaca cttatccgat aacacctgcc gtgcgcgttt tgcgtgaaaa
    14161 cggcatcgaa tttgaacctt ttacctatgc ctatgaggaa cacggcggca cggcgcagtt
    14221 tgcccgacta ttcggcaaag acgaacactt ggtcattaaa accattgttt tgcaagatga
    14281 aaacgggaat gggctgattg tcttgatgca cggcgacaaa cagatttcca cgcgcaatct
    14341 ggctcggcat ttgggtgcga aacgcatcga acccgctacg cccgcacagg caaacaagtg
    14401 gacgggctat ctggtcggcg gcacaacgcc gttcggcatc cggacaaaat tggatattta
    14461 cgtcgaacag tcggtgatgg atttggaaac catctatatc aacggcggga aacgcgggtt
    14521 cattatcggt atccgtcccg gagatttaaa tattttgaac ccgaaaacaa tacaggcggc
    14581 ggtttgaccg ggaagtataa ggaacaatat ggacaaagat ttgtatgccg tattgggcgt
    14641 gtcgccgcag gcgggggcgg acgaaatcaa acgcgcctac cgcaagctgg caatgaaata
    14701 ccatcccgac cgcaatccgg gcaatccgca ggcggaagaa aagttcaaag aaatccaacg
    14761 ggcttacgat acgctttccg acctgtcgaa acggatgcaa tacgacgcgt ccttcagacg
    14821 gcatgaggaa cgcgggcggc aggaagaggc attccgccgc gaacaggcgc gcagggagca
    14881 gttttaccgc gaacagatgc gccgcgaaca ggcgttcaga caggcgtttg aacggcaggc
    14941 atcacgttcg tgccatactt acgaaccgtc cggcggcgga agcgggcgca actatgtcct
    15001 cgccgcctac atcctgttcg gtttgggtgc aatcatgctg ttcatgccca tagtcggcgt
    15061 gattttcgcc tatatgccca tagtcggcgt gattctcgcc tatatgaaac ggaacagttt
    15121 ggacagcatt gtctatgccg cacataccga atacctgatt aaaacctttt ggcgcacatt
    15181 ttggctttat attttgggtg cgctgactgc ccttttgggt atcggcgtgc tgattattat
    15241 tgcaacgaac gtctggtatt tctaccgcat catcgccggc tttatccgct tcaacggcgg
    15301 cagggcggtt gcacccgaga aatggatata gtatggctta cctgttaatc agcatcgtgt
    15361 tcagcgtgtc ggtttccatt ttgctgaaaa tggcaaggaa gaaaaaaatc gacatcgcgc
    15421 aggcggtcgc cgtcaattat gtggtcgcgg tcatactgac cctgctggta ttgaagccgg
    15481 atgtcggcaa tatcggcgca tttttgccga catggtggct gtttgccgca ttgggcgtgc
    15541 tgctgccgtc cgtatttgtc attatgggca aatccgtaga atccgccggt atcgtcaaat
    15601 ccgacgcggc gcagcgtttg tcgctgtttt tgccgattgt tgccgccttg acgctgtttg
    15661 gcgaaaaact cagcgaaggc agactaatcg ggctgtgcct cgcatttgcc gcactgttct
    15721 gcctgctttg gaaacacagc ggtggcaaaa aatcaggaag cgcgtggcgg caggcggcat
    15781 tgctgctggg cgtgtgggca ggttacggca ttatcgatat cctgttcaaa cagcttgcca
    15841 aaagcggaac ggcatttgcg ggcaacctgc tggttgcatt tgtgctggcg ggtgtgctga
    15901 tgtttgcctg cctgtttgcc aaatcggtca gatggcgtgt tgagagtgtg gtcggcggca
    15961 tattcttggg cggtttgaat tttatgaata tcgtaaccta catcaccgcg caccaaatga
    16021 tgaaggataa tccgaccttg gtttttgccg gtatgaatat cggcgtgatt gttttgggta
    16081 cgctttcggg cgcattgttc tttaaggaaa aaatcaacac aatcaatacg gcgggaatcg
    16141 tgttggcact gtgttctatc gcctgcctgt tttattgggg ggaagtcaag gtactgttcg
    16201 gcatataatc cggctgattg atataacaaa atgccgtctg aagcagcatc cctgcttcag
    16261 acggcatttg tctgcaacgt tacagatggg ggttcatcag gttctcggga gagaggatgc
    16321 ggttgagttc ttcttcgctc aacagcccgc gttccaagac aacctcgcgc acgcctttgc
    16381 cggtttgggc gcagattttg ccgaccaaat cgccgttgtg gtgtccgata tacggattca
    16441 gataagtcac caaaccgatg gagttgaaaa cgtaacgttc gcagatttcg cggttgaccg
    16501 taatgccttt gacgcatttg tcggacaggt tgactgcggc attgcccaag agggaaatgg
    16561 tttcaaacat acattgggcg atgaccggct ccatcacgtt taattgcagt tgcccggctt
    16621 cggcggcgaa ggtaatcgtc gtgtcgttgc cgatgacttt gaagcagact tggttgacca
    16681 cttcgggaat cacgggattg actttggcgg gcattatgga agaaccggcc tgcaattcgg
    16741 gcaggttgat ttctttcaag ccggcacgcg ggccggaaga gagcaggcgc aagtcgttgc
    16801 agattttgga gagtttgacc gccgtgcgct tcaatgcgcc gtgtaccatc acatatgcgc
    16861 cgcagtcgga ggtcgcctca atcaggtttt cggtcagttt gcaaggcaag ccgctgactt
    16921 cggagagttt tttgaccacc agttcggcgt agcctttggg cgtgttcacg cccgtgccga
    16981 ttgccgttgc gcccaaattg acttccaaca gcagttggcg ggtgcggtcg aggttgagga
    17041 tttcttcttc caacaacact tggaaagatt ggaattcttg gccggcagtc atcggcacgg
    17101 catcttgaag ctgggtgcgg cccattttca aaacgtcttt aaactcttcg gctttggcgg
    17161 caaaggcgtt tttcaggacg gccagtttgt cgagcaattc gccgatgctg taatacacgg
    17221 caaggcggaa gccggtaggg taggcatcgt tggtggattg gctggcgttg acatgaacca
    17281 tcggattgac gatatcgtag cggccttttt cgtatcccaa gacttccaat gcgaggttgg
    17341 cgatgacttc gttggtgttc atattgaccg aagtacccgc accgccctga tacacatcgg
    17401 acgggaattg gtcgaggcag cggttgttca gcagaacttc gtcgcaagcc ttttcaatgg
    17461 cggcggcgat ttcgggcttg accgcgccca acttaccgtt tgcctgtgcc gtcgcctttt
    17521 tcaccatcac catactgcgg acaaactgcg gcacgtcaga aattttttgt gtggagattt
    17581 taaagttttc aatggcgcgc agggtgtgga tgccccaata cacttcggcg ggaatctcgc
    17641 ggtcgcccaa taaatcgtgt tcgatacgga cagtcatgtt tttacctttg taagtcggat
    17701 aattaatatt gaaaaaatgc gccatcggaa agatgccgcc gcaggacgaa cactataccg
    17761 gccggatgaa attgtccata tcgtatgccg tctgaaaacg ggaaacgttg ttttcgg
//
LOCUS       DAXISH010000046        17408 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.046, whole genome shotgun sequence.
ACCESSION   DAXISH010000046 DAXISH010000000
VERSION     DAXISH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 17408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17408
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.046"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(409..744)
                     /locus_tag="ACFOV4_001496"
     CDS             complement(409..744)
                     /locus_tag="ACFOV4_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFC7619475.1"
                     /translation="MFGKAGLGGLMKQAQQMQENMKKAQAKLAETEIEGEAGNGLVKI
                     TMTCAHEVRKIDISPDLIQEAADDKEMLEDLILAALKSARGKAEETANKTMGAFTQGL
                     PPGVGDFFR"
     gene            complement(824..2953)
                     /gene="dnaX"
                     /locus_tag="ACFOV4_001497"
     CDS             complement(824..2953)
                     /gene="dnaX"
                     /locus_tag="ACFOV4_001497"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFC7619476.1"
                     /translation="MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLT
                     GTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAGRYVDLLEIDAASNTGID
                     NIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH
                     KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKITYAPPALQLLGRAAAGSMRDAL
                     SLLDQAIALGSGKVAENDVRQMIGAVDKQYLYELLTGIINQDGAALTAKAREMAACAV
                     GFDNALGELAILLQQLALIQAVPSALAHDDPDSDILHRLAQTISGEQIQLYYQIAVHG
                     KRDLSLAPDEYAGFMMTLLRMLAFAPLAAASCDANAVIENTELKSPSAQTAEKETAAK
                     KPQPRPEAETAQTPVQTASAAAMPSESKTAEPVSNQENNDVPPWEDAPDEAQTAAGTA
                     QTSAKSIQTASEAETPPENQVSKNKAADNETNAPLSETPSENPIQATPNNEAVETETF
                     AHEAPAEPFYGYGFPDNDCPVEDGAEIPPPDWEHAAPADTAGGGADEEAEAGGIGGNN
                     TPSAPPPEFSTENWAAIVRHFARKLGAAQMPAQHSAWTEYHPDTGLMVLAMTAEARAT
                     ADKKRLDKIRDTLAQAYGLQLTLQTQDWRDEAGRETPAMQDKRVQAEDRQKAQALLEA
                     DPAAQKILQAFGAQWQPESVELAANRP"
     misc_feature    complement(1725..1764)
                     /gene="dnaX"
                     /locus_tag="ACFOV4_001497"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01843"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="This ribosomal frameshift element is known only in
                     the genus Neisseria; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01843"
     gene            complement(3048..5024)
                     /gene="mutL"
                     /locus_tag="ACFOV4_001498"
     CDS             complement(3048..5024)
                     /gene="mutL"
                     /locus_tag="ACFOV4_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFC7619477.1"
                     /translation="MSRIAALPDHLVNQIAAGEVVERPANALKEIVENSIDAGATAID
                     VELAGGGIRLIRVSDNGSGIHPDDIGLALHRHATSKIKTLNDLEHVASMGFRGEGLAS
                     IASVSRLTLTSRQEDSSHATQVKAEDGKLSSPTAAAHPVGTTIEAAELFFNTPARRKF
                     LKSENTEYAHCATMLERLALAHPHIAFSLKRDGKQVLKLPAQSLHERIAAIVGDDFQT
                     ASLEIDSGNGALRLYGAIAKPTFAKGKTDKQYCFVNHRFVRDKVMLHAVKQAYRDVLH
                     NALTPAFVLFLDLPPEAVDVNVHPTKTEIRFRDSQQVHQLVFHTLNKALADTRADLTE
                     SVSNAGEVLHDITGVTPAPRPSENDSENLFDSASNYPTGNKPDTRNAFGSAGKTAPMP
                     YQAARAPQQHSLSLRESRAAMNTYAELYKKTDDIDLELSRFEQARFGNMPSETPAPQT
                     DTPLSDGIPSPSELPPLGFAIAQLLGIYILAQAEDSLLLIDMHAAAERVNYEKMKRQR
                     QENGRLQSQRLLIPVTFAASHEECAALSDHADALAGFGLELSDMGGNTLAVRAAPAML
                     GKADVVSLARDVLGELAQVGSSQTIEEHENHILATMSCHGSVRAGRRLTLPEMNALLR
                     DMENTPRSNQCNHGRPTWVKLTLKELDALFLRGQ"
     gene            5168..5353
                     /locus_tag="ACFOV4_001499"
     CDS             5168..5353
                     /locus_tag="ACFOV4_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3460 family protein"
                     /protein_id="HFC7619478.1"
                     /translation="MYHYQSDATQFLNRLIEEKPELEQQRLENRGLLWDVELSPEEQE
                     NFEAAKVAKKPYTYYQD"
     gene            5364..6032
                     /locus_tag="ACFOV4_001500"
     CDS             5364..6032
                     /locus_tag="ACFOV4_001500"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC7619479.1"
                     /translation="MTTNLSNVAPDLQNYLNAIGEPEHPVLTRLREKTEHHRMGKMAI
                     AREQAAVLVWLAKLIRAEKYLEIGVFTGYSSTALALALPEHGRITACDINVTFTDTAR
                     QVWNEAGVAHKISLHLQPALLTLDDLIAQGEAGSYDLALIDADKPPTPQYFERCLKLV
                     RQGGIIAIDNILLNGRVMREAASDAPPSVGILKDFNQNLPNDTRIVPITLPVGDGLTL
                     LLKK"
     gene            6032..6748
                     /locus_tag="ACFOV4_001501"
     CDS             6032..6748
                     /locus_tag="ACFOV4_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system YbgF family protein"
                     /protein_id="HFC7619480.1"
                     /translation="MKTKLPLFIIWLSVSAACSSPVSRNIQDMRPEPQAEAGSSDAIP
                     YPVPTLQDRLDYLEGRIVRLSNEVETLNGKVKALEHAKTHPSSRAYVQKLDDRKLKEH
                     YLNTEGGSASAHTVETAQNLYNQALKHYKSGRFAAAAALLKGADGGDGGSIAQRSMYL
                     LLQSRARMGNCESVIEIGRRYANRFKGTPAAPEAIFKIGECQYRLQQKDIARATWRSL
                     IQTYPGSPAAKRAAAAVRKR"
     gene            6788..7273
                     /gene="purE"
                     /locus_tag="ACFOV4_001502"
     CDS             6788..7273
                     /gene="purE"
                     /locus_tag="ACFOV4_001502"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFC7619481.1"
                     /translation="MIQIGIIMGSNSDWPVMRQAAQFLEEFGVEYEACVVSAHRTPDL
                     MFQYAETARARGIKAIIAGAGGAAHLPGMVAAKTTVPVLGVPVPSKYLRGEDSLLSIV
                     QMPKGVPVATFAIGEAGAANAALFAVSMLANETPELAQKLADFRAKQEQAVLSMELEQ
                     I"
     gene            complement(7456..8910)
                     /locus_tag="ACFOV4_001503"
     CDS             complement(7456..8910)
                     /locus_tag="ACFOV4_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="HFC7619482.1"
                     /translation="MTTQTIKFHMKPETFKQNAAISLQDKPLRKSLRTAMDMLMTKRK
                     AVLTDEEELQSLRDLCEHVRQRSLSKLPALLEQLEENLTKLGVKVHWAETPTEACQII
                     HDIITAKNGKLMVKGKSMVSEEIELNHYLEAKGIKAVESDLGEFIVQMAGEKPTHIVM
                     PAIHKTKEQVSELFHQNLGTPLTDDVDQLTGFARKALRDIYSTADVGLSGVNFAVAET
                     GTLCLVENEGNGRLSTTVPPVHIAITGIEKVVAKLSDIPPLYSLLPRSAIGQNITTYF
                     NMITGPRRSEELDGPQEMHLVLLDNGRSQAYAEDQMRRTLQCIRCGACMNHCPVYTRI
                     GGAAYGTTYPGPIGEIISPHLLGLDATRDLPTACTMCGACVEVCPVRIPITEQMQRLR
                     VEAQRSPTETVPHPIRGQGASHTFGEQMAWRTFNGIFSGSKTYRAFGWAATKFRNLTP
                     RKQLGWTQNRVPMKPAKKTLHELMAEKMRQKEQA"
     gene            complement(8907..9608)
                     /locus_tag="ACFOV4_001504"
     CDS             complement(8907..9608)
                     /locus_tag="ACFOV4_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HFC7619483.1"
                     /translation="MSARENILAKLKKADALPMEEPAVFDYYREKGVSWDSEAERLKH
                     WAAAMRAVKTEIYWVTKSNWMQVFREAAEGKGLKNILLPLATEHGQIARAALAGSNIE
                     PIVFEREIDTWKTEFFTNINAGFSGAQCGIARTGTLMLFSSPEEPRTLSLVPPVHFCL
                     FDTSKMYNEFHNAVEGEKLVENGMPTNVFLISGPSKTADIQLTLAYGAHGPRDLVILA
                     ILPDHISPADLEENA"
     gene            complement(9605..10384)
                     /locus_tag="ACFOV4_001505"
     CDS             complement(9605..10384)
                     /locus_tag="ACFOV4_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HFC7619484.1"
                     /translation="MSATIPPKIIRYDSNPTDVYFFGTCVLDLFMPEAGMDAITLIEQ
                     QGIRVHFPMAQSCCGQPAYSSGHPTEAFDVARAQLDLFPEEWPIVVPSGSCGGMMKHH
                     WPTLFKGSEYEERAVDCAGRIIEFTHFLLAIGFKPEDKGEPLKVAVHTSCAARREMNV
                     HLSGWQLIDGMENVERIVHDHESECCGFGGTFSVKQADISGAMVTDKVAALKETGATE
                     IISADCGCMMNIGGKIAKDEPDMPRPKHIASFLLERTGGKA"
     gene            10668..12074
                     /locus_tag="ACFOV4_001506"
     CDS             10668..12074
                     /locus_tag="ACFOV4_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC7619485.1"
                     /translation="MEKNTLSARAPSPWLPLLLAIAIFMQMLDATILNTALPEIATDL
                     DESPLDMQLAVVAYTLTVALLIPLSGYLADRFGTKKVFFGSIAVFILGSALCAASGSL
                     FELTLSRVVQGIGGSMLVPIPRLTILRMYDKSKLLNAINYAVMPALIGPVLGPLAGGY
                     LVEYASWHWIFLLNLPIGLLGFILGRNIMPDIKGSNISLDFKGYLIFSAAACLLLLSA
                     ESLSHALPPYFALLPLCGGLLFARRYFRHMKTASKPIYSADLFLIRTFRLGLAGNLFS
                     RLGISSIPFLMPLMFQVAFGFGASLSGWLVAPVALSSLLVKPLIAPLMKRFGYRTVLL
                     WNTKLLAAFIMLLALPDGNSSLWIWIFLSLAIGACNSLQFSAMNTLTLADLRPQQTGS
                     GNSLMAVNQQLAISMGIVVGALILKNWTFLIPASSGLHSAFRMTLLSIGGITLASSLV
                     FKRLHVSDGANLTRNTLS"
     gene            12186..13712
                     /locus_tag="ACFOV4_001507"
     CDS             12186..13712
                     /locus_tag="ACFOV4_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003765285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HFC7619486.1"
                     /translation="MKTRSLISLLCLLLCSCSSWLPPLEERTESRHFNTSKPVRLDNI
                     LQIRHTPHTNGLSDIYLLNDPHEAFAARAALIESAEHSLDLQYYIWRNDISGRLLFNL
                     VYLAAERGVRVRLLLDDNNTRGLDDLLLALDSHPNIEVRLFNPFVFRKWRALGYLTDF
                     PRLNRRMHNKSFTADNRATILGGRNIGDEYFKVGEDTVFADLDILATGSVVGEVSHDF
                     DRYWASHSAHNATRIIRSGDIGKGLQALGYNDETSRHALLRYRETVEQSPLYQKIQTG
                     CIDWQSVRTRLISDDPAKGLDRDRRKLPIAERLQDALKQPEKSVYLVSPYFVPTKSGT
                     DALAKLVQDGIDVTVLTNSLQATDVAAVHSGYVKYRKPLLKAGIKLYELQPNHAVPAT
                     KDKGLTGSSVTSLHAKTFIVDGKRIFIGSFNLDPRSARLNTEMGVVIESPKIAEQMER
                     TLADTTPEYAYRVTLDRHNRLQWHDPATRKTYPNEPEAKLWKRIAAKILSLLPIESLL
                     "
     gene            13920..14453
                     /locus_tag="ACFOV4_001508"
     CDS             13920..14453
                     /locus_tag="ACFOV4_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFC7619487.1"
                     /translation="MFPPDKTLFLCLSALLLASCGTTSGKHRQPKPKQTVRQIQAVRI
                     SHIDRTQGSQELMLHSLGLIGTPYKWGGSSTATGFDCSGMIQFVYKNALNVKLPRTAR
                     DMAAASRKIPDSRLKAGDLVFFNTGGAHRYSHVGLYIGNGEFIHAPSSGKTIRTEKLS
                     TPFYAKNYLGAHTFFTE"
     gene            complement(14496..15797)
                     /gene="aroA"
                     /locus_tag="ACFOV4_001509"
     CDS             complement(14496..15797)
                     /gene="aroA"
                     /locus_tag="ACFOV4_001509"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFC7619488.1"
                     /translation="MTESVRLPVARLKPSTVALPGSKSISNRTLLLAALSDNACEIHS
                     LLKSDDTDRMLEALDKLGVQIEYLAEDRLKVHGTGGRFPNRTADLFLGNAGTAFRPLT
                     AALAVLGGDYHLHGVARMHERPIGDLADALRIAGADVEYLGKEHYPPLHIGERQDRGE
                     RVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVGELISKPYIDITLKLMAQFGVQVIN
                     EGYRVFKIPADARYHAPEHLHVEGDASSASYFLAAGLIAATPVRVTGIGANSIQGDVA
                     FARELEKIGADVVWGENFVEVSRPKERAVRAFDLDANHIPDAAMTLAIVALATGQTCT
                     LRNIGSWRVKETDRIAAMANELRKLGAKVVEEAEAIHITPPETPTPDAVIDTYDDHRM
                     AMCFSLVSLLGVPVVINDPKCTHKTFPTYFDVFSSLTETAE"
     gene            16189..16665
                     /gene="greA"
                     /locus_tag="ACFOV4_001510"
     CDS             16189..16665
                     /gene="greA"
                     /locus_tag="ACFOV4_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFC7619489.1"
                     /translation="MQKIPLTVRGAELLKQELQQLKSVARPEVIEAIAEARSHGDLSE
                     NAEYEAAKERQGFIEGRISELEHKLSVAHIINPTEIHAEGKIVFGTTVTLEDLETEEH
                     VTYQIVGEDEADIKQGKIYVGSPIARALIGKEEGDTAEVQAPGGVREYDIIEVRYI"
BASE COUNT         3681 a         4718 c         4837 g         4172 t
ORIGIN      
        1 ttcgcgggaa tgacggtcgg gggtttctgt tttttccgat agattcctgt ggtttttcgg
       61 ttactggatt cccgcgttcg cgggaatgac ggggtgtaag tttctgctcc gacggggttg
      121 gattcccgct ttcacgggaa tgacgaagtt tcagacggca tttaagcggt acggatgtgt
      181 aaataatggt agggtgggct tcagcctgcc gattcccgct attcttgccg tttttgcgtt
      241 cttatcattc tcactgtttt taccgttcac gccgaatcct gcaaactgat gccgtcattc
      301 ccgcgaaggc gggaatccag acccgtcggc acggaaattt atcgagtaaa acggtttctt
      361 agattctacg ttctagattc ccgcctgcgt gggaatgacg gtcgggtatc agcggaagaa
      421 gtcgcccact ccggggggta gaccttgcgt gaatgcgccc attgttttgt ttgcggtttc
      481 ttcggctttg ccccgggcgg atttgagggc ggcgaggatg aggtcttcga gcatttcttt
      541 gtcgtcggcg gcttcttgaa tcaaatcggg gctgatgtcg attttgcgta cttcgtgcgc
      601 gcaggtcatt gtgattttga ccaggccgtt gcctgcttcg ccttcgattt cggtttcggc
      661 aagtttggct tgcgcttttt tcatattttc ctgcatttgc tgcgcctgtt tcatcaggcc
      721 gcctaatccg gcttttccga acatactgaa tactcctgtc tgttttgatt gaatgaggga
      781 aacggcaatg ccgtccgaag ggttcgggcg gcattatatc tgtttatggc cggtttgctg
      841 ccaattccac tgattcgggc tgccattgcg cgccgaatgc ttggaggatt ttttgtgcgg
      901 cggggtcggc ttcgagcaat gcttgtgctt tttgcctgtc ttcggcttgg acgcgcttgt
      961 cctgcatcgc gggggtttcc ctgccggctt cgtcgcgcca gtcttgggtt tgcagggtga
     1021 gttgcagtcc gtaggcttgg gcaagggtgt cgcggatttt gtcgagacgt tttttgtcgg
     1081 cggtggcgcg ggcttcggcg gtcatcgcca aaaccatcag gccggtgtcg ggatggtatt
     1141 ccgtccacgc ggagtgttgc gccggcattt gcgccgcgcc gagtttgcgg gcgaaatgcc
     1201 ggacgatggc tgcccagttt tcggtggaaa attcgggcgg cggggcggac ggcgtgttgt
     1261 ttccgccgat gccgcctgct tctgcttctt cgtccgcgcc tccgcctgcg gtatcggcag
     1321 gggcggcgtg ttcccaatcg ggcggcggga tttctgcgcc gtcttctacg gggcagtcat
     1381 tatccggaaa gccgtaaccg tagaaaggtt ctgcaggggc ttcgtgtgca aatgtttccg
     1441 tttcaacggc ttcattattc ggtgttgcct gaatggggtt ttcagacggc gtttcggaca
     1501 agggggcatt ggtttcgttg tcggctgcct tgttcttgga aacttggttt tcgggcggcg
     1561 tttcggcttc ggatgccgtc tgaatgcttt ttgccgacgt ttgcgccgtg ccggctgcgg
     1621 tttgggcttc gtccggcgcg tcttcccaag gcggaacatc gttgttttct tgattggaaa
     1681 cgggttcggc agttttgctt tcagacggca ttgccgctgc ggatgccgtc tgaacgggtg
     1741 tttgggcggt ttccgcttca gggcgcggtt ggggcttttt tgcggcggtt tccttttcgg
     1801 cggtttgtgc cgatggggat tttagttcgg tattttcaat cacggcattt gcatcacacg
     1861 atgctgctgc caagggcgca aacgccagca tacgcagcag ggtcatcata aagccggcgt
     1921 attcgtcggg ggcgaggctc aggtcgcgtt tgccgtggac ggcgatttgg tagtaaagct
     1981 ggatttgttc gccgcttatg gtttgggcga ggcggtgcaa aatatcggaa tcggggtcgt
     2041 cgtgcgccaa ggcggagggg actgcctgta tcagggcgag ttgttgcagc agtatggcga
     2101 gttcgcccaa ggcgttgtca aagccgacgg cacacgccgc catttcccgc gctttggcgg
     2161 tcagggctgc gccgtcttgg ttgatgatgc ctgtcaagag ttcgtaaagg tattgtttgt
     2221 caaccgcgcc gatcatttgg cggacatcgt tttcggcaac tttgcccgaa cccagggcga
     2281 tggcttggtc gagcaggctt aaggcatcgc gcatcgatcc ggcggcggcg cgtcccaaaa
     2341 gttgcagggc ggggggggcg taggtgattt tttcgctgtc gaggacgtgg gcgaggtggt
     2401 cggcaacctg ctgcgcggtc atattgcgta agacgaattg caggcagcgg ctcaagacgg
     2461 taacggggac tttgtgcgga tcggtcgtgg caaggatgaa tttgacgtgt tcgggcggct
     2521 cttccagcgt tttgagcata gcgttgaacg cgcttttgga aagcatatgc acttcgtcga
     2581 tgatatagac tttgtatttg ccggcagtcg gcgcgtattg ggcgttttcc aatacttcgc
     2641 ggatgttgtc gatgcctgtg ttggaggcgg cgtcgatttc caataaatct acatagcgtc
     2701 cggcatcgat ttgggtgcag ctttggcaca cgccgcaagg ttcgccgtgt tgcgcgtttt
     2761 cgcagttgag gcttttggca aggatgcggg cgatggtggt tttgcccacg ccgcgcgtac
     2821 cggtcagcag gtaggcgtgg tgcagcctgc cttcgtccaa ggcattttgc agggctttga
     2881 cgacgtgttc ctgaccgact aagtcggcaa aggttttggg ccgccatttt cgggcgagaa
     2941 cttgataggc catatttttc tcttggtttc ggtcgtgatg tttctgtcgg tgcgtcggaa
     3001 tgccgtctga acggcggctt cgggcggcgt attctagcac tttcggctta ctgtccgcgc
     3061 aagaacagtg cgtccaattc tttcaaagtc agtttgaccc aagtcggcct gccgtggttg
     3121 cactggttgc tgcgcggcgt gttttccata tcgcgcagga gcgcattcat ttccggcagg
     3181 gtaagccgac ggccggcgcg gactgagccg tggcaggaca tggtggcgag gatgtggttt
     3241 tcgtgttcct cgatggtttg gctgctgccg acttgggcga gttcgcccaa tacgtcgcgg
     3301 gcgagggaga cgacatcggc tttgcccaac attgcgggcg cggcacgaac ggcgagggta
     3361 ttgccgccca tatcggacaa ctccagcccg aagcctgcca gtgcatcggc atggtcggag
     3421 agggcggcgc attcttcgtg ggacgcggca aaggttacgg gaataagcag gcgttggctt
     3481 tgcagcctgc cgttttcctg acgttggcgt ttcatttttt cgtagttgac gcgttcggcg
     3541 gcagcgtgca tatcgatgag caacagactg tcttctgctt gggcaaggat gtagatgcct
     3601 aatagttggg caatggcaaa accgagcggc ggcagttcgg atggggacgg gatgccgtct
     3661 gaaagcggcg tatctgtttg gggagcaggc gtttcagatg gcatattgcc gaaacgtgcc
     3721 tgctcgaatc ggcttaactc aaggtcgatg tcgtcggttt ttttgtaaag ctcggcatag
     3781 gtgttcattg ccgcgcggct ttcgcgcagg gacaggctgt gttgttgcgg tgcacgcgcg
     3841 gcttggtaag gcataggcgc ggttttgcct gctgaaccaa aggcattgcg tgtatcgggt
     3901 ttgttgcccg tcgggtagtt ggatgcgcta tcaaacagat tttcgctgtc gttttcagac
     3961 ggccttggtg caggagtaac gccggtaatg tcatgcaaca cttcgcctgc gttgctgacg
     4021 ctttcagtta agtcggcgcg cgtgtcggca agggctttgt tgagcgtgtg gaacacgagt
     4081 tggtgcacct gctggctgtc gcggaagcgg atttcggttt tagtaggatg gacgttgaca
     4141 tccacggctt cgggcggcag gtcgagaaag aggacgaaag caggtgtcag cgcgttgtgc
     4201 aatacgtcgc ggtatgcctg tttgacagca tggagcatga ctttgtcgcg cacgaagcga
     4261 tggttgacga agcagtattg tttgtcggtt ttgcctttgg cgaaagtcgg cttggcaatc
     4321 gcgccataga gccgcagtgc gccattgccg ctgtcgattt ccagggatgc cgtctgaaag
     4381 tcatcgccga caatggcggc aatccgttcg tgcaggcttt gggcaggaag ttttaacact
     4441 tgtttgccgt cgcgtttgag cgagaaggca atgtgcggat gcgccagcgc gaggcgttcg
     4501 agcatcgtgg cgcagtgggc gtattcggtg ttttcggatt tgaggaactt gcgccgcgcg
     4561 ggggtgttga agaagagttc ggcggcttcg atggtggtgc cgacggggtg ggcggcggcg
     4621 gtggggctgc tgagtttgcc gtcttcggct ttgacttggg ttgcgtgcga actgtcttct
     4681 tgacggctgg tcagggtcag gcggctgacg gaggcgatac tggccaagcc ttcgccgcga
     4741 aagcccatgc tggcaacgtg ttccaaatcg tttaaggttt tgattttgct ggtggcgtgg
     4801 cggtggagcg caagcccgat gtcgtccgga tggataccgc tgccgttgtc gctgacgcga
     4861 atcaggcgga tgccgccgcc cgccagctcg acatcaatcg ccgtcgcgcc tgcatctatg
     4921 ctgttttcaa cgatttcttt taaggcgttg gcggggcgtt cgaccacttc gccggcggcg
     4981 atttggttga cgagatggtc gggcagggcg gcaattcggg acatggcatg ggcttccgtt
     5041 tcaaaaaacg cttcattcta taataaaacc ccttaccttt ctgcctgtat tcttgataaa
     5101 agccgtttat cccgtttgga aaataccagt ataatcacgc catattccgt aaaattggag
     5161 cacaaagatg tatcactacc aatccgatgc cacacaattc ctcaaccgcc tgattgaaga
     5221 aaaacctgag ttggaacagc agcgtttgga aaacaggggg cttttgtggg atgtcgaact
     5281 tagtcccgaa gaacaggaaa acttcgaggc ggcaaaagta gcgaaaaaac cttataccta
     5341 ttaccaagac tgaacccgcc gaaatgacga ccaatctgtc caatgtcgca ccggacctgc
     5401 aaaactattt gaatgccatc ggcgaacccg aacatcccgt tttgacgcgg ctgcgtgaga
     5461 agaccgagca tcaccgtatg ggcaaaatgg cgattgcgcg cgaacaggcg gcggttttgg
     5521 tttggctggc aaagctgatc cgtgcggaaa aatatctgga aatcggcgta tttaccggat
     5581 acagcagcac cgcgcttgca ttggcgttgc ccgaacacgg gcggattacc gcctgcgaca
     5641 tcaatgtaac ctttaccgat acggcgcgtc aggtttggaa cgaggccggt gtggcacata
     5701 aaatcagcct gcacctgcaa cccgcattgc tgacattgga tgatttgatt gcacagggtg
     5761 aagccggaag ctacgatttg gcactgatag acgcagacaa accgcccacg ccgcaatatt
     5821 tcgagcgttg cctcaagctt gtccggcaag gcggcatcat tgccatcgac aatattttgt
     5881 tgaacggaag ggtgatgcgc gaagcggctt ccgatgcgcc gcccagcgtc ggcatcctca
     5941 aagattttaa tcaaaacctg ccgaacgata cgcggattgt ccccatcacc ctgcccgtcg
     6001 gcgacggttt gaccctgctt ctgaaaaaat aatgaagacc aaattaccgc tttttatcat
     6061 ttggctgtcc gtatccgccg cctgttcttc ccctgtttcc cgcaatattc aggatatgcg
     6121 gcccgaaccg caggcagagg caggtagttc ggacgctatt ccctatcccg ttccgacctt
     6181 gcaagaccgt ttggactatc tggaaggcag aatcgtccgg ctgtcgaacg aagtggaaac
     6241 cttaaacggc aaagtcaaag cactggagca tgcgaaaaca cacccttcca gcagggcata
     6301 cgtccaaaaa ctcgacgacc gcaagttgaa agagcattac ctcaataccg aaggcggcag
     6361 cgcatccgca cataccgtcg aaaccgcaca aaacctctac aatcaggcac tcaaacacta
     6421 taaaagcggc aggttcgccg ctgcagccgc cctgttgaaa ggcgcggacg gaggcgacgg
     6481 cggcagcatc gcgcaacgca gtatgtacct gttgctgcaa agcagggcgc gtatgggcaa
     6541 ctgcgaatcc gtcatcgaaa tcgggcggcg ttacgccaac cgtttcaaag gcacccctgc
     6601 cgcacccgaa gcaatattca aaatcggcga atgccaatac aggttgcagc aaaaagacat
     6661 tgcaagggcg acttggcgca gcctgataca gacctatccc ggcagcccgg cggcaaaacg
     6721 cgccgcagca gccgtacgca aacgatagtt tttccgcttt ttaccccatc cgcaccaagg
     6781 aggatttatg attcaaatcg gcatcatcat gggcagcaac agcgattggc ccgttatgcg
     6841 gcaggcagcg cagtttcttg aagagttcgg cgtagaatat gaggcgtgcg tcgtttccgc
     6901 acaccgcacc ccggatttaa tgttccaata cgccgaaacc gcacgggcgc gcggcatcaa
     6961 agccatcatc gcgggtgcgg gcggcgcggc gcatttaccc ggtatggttg ccgccaagac
     7021 caccgtcccc gttttgggcg tacccgtccc cagcaaatac ctgcgcggcg aagattcgct
     7081 tttatcgatt gtacaaatgc ccaaaggcgt acccgtcgcc acattcgcca tcggcgaggc
     7141 aggcgcggca aatgccgcat tgttcgccgt ttccatgctc gccaacgaaa cccccgaact
     7201 ggcgcaaaaa ctggcagact tccgagccaa acaggaacag gctgttttga gtatggaatt
     7261 ggaacagatt taaaacccgc cgtccgcgaa tatatagtgg cttaaattta aaccagtacg
     7321 gcgttacctc gccttgccgt actatttgta ctgtctgcgg cttcgtcgcc ttgtcctgat
     7381 ttttgttaat ccactataca aatgccgtct gaagccctgt ttcgggtttc agacggcatt
     7441 tttgcgaaca actttttatg cctgttcttt ttggcgcatt ttttctgcca tcagttcgtg
     7501 cagggttttc ttcgccggtt tcatcggcac gcggttttgc gtccaaccca actgtttgcg
     7561 cggggtcagg ttgcggaact tggtggctgc ccaaccgaag gcgcggtagg ttttgctgcc
     7621 gctgaaaata ccgttgaatg tgcgccacgc catttgttcg ccgaaggtat gcgatgcgcc
     7681 ttgcccccgg atggggtgcg gcacggtttc ggtcggcgaa cgttgcgctt caacgcgcaa
     7741 acgctgcatt tgttcggtaa tcgggatgcg taccggacaa acttccacgc acgcgccgca
     7801 catcgtgcag gcggtcggca ggtcgcgagt ggcatccaag cctaacaggt gcggggaaat
     7861 aatctcgcca atcggaccgg gataggttgt gccgtatgcc gcgccgccga tgcgggtata
     7921 aaccgggcaa tggttcatac acgcgccgca acggatacat tgcagggtgc ggcgcatttg
     7981 gtcttcggca taagcctggc tgcggccgtt gtcgagcaga accaagtgca tttcttgcgg
     8041 accgtctaat tcttcactgc ggcgcgggcc ggtaatcata ttgaaatagg ttgtgatgtt
     8101 ttgaccgatg gcggagcgcg gcagcagact gtacaagggt gggatgtcgg acaatttcgc
     8161 caccactttt tcaatgccgg taatagcgat atgcacggga ggaacggtgg tactcaagcg
     8221 accgttgcct tcgttttcca ccagacacag cgtacctgtt tcagcaacgg cgaagttcac
     8281 gccgctcaag ccgacatcgg cagtgctgta aatatcgcgc agggctttgc gggcgaagcc
     8341 ggtcagttgg tccacatcgt ctgtaagcgg tgtgccgagg ttttggtgga acagttcgct
     8401 cacctgttct ttggttttat ggattgcggg catcacgata tgggtcggtt tttcacctgc
     8461 catttggacg atgaactcgc ccaagtcgct ttccaccgct ttaatgcctt ttgcttcaag
     8521 ataatggttc agctcgattt cctcgctgac catcgatttg cctttgacca tcagcttgcc
     8581 gtttttggct gtgatgatgt cgtggataat ttggcaggct tcggtcgggg tttctgccca
     8641 gtgcactttc acgcccagct tagttaggtt ttcttccagc tgctccagca gggcaggtaa
     8701 tttagacaat gaacgctgac ggacgtgttc gcacaaatcg cgcaagcttt gcagctcttc
     8761 ttcgtcggtc aaaacggctt tgcgtttggt catcagcata tccatcgcgg tacgcaggct
     8821 tttgcgcaaa ggcttgtctt gaagggaaat tgcggcgttt tgcttgaaag tttccggctt
     8881 catgtggaac ttgatggttt gcgtagtcat gcgttttcct ccaaatcggc aggggaaatg
     8941 tggtcgggca ggatggcgag gatgaccaaa tcgcgcgggc cgtgcgcgcc gtaagcaagc
     9001 gtcagttgga tgtctgcggt tttggacggg ccggaaatca ggaatacatt ggtcggcata
     9061 ccgttttcca ccagtttttc gccttcgacg gcattatgaa actcgttgta catcttggac
     9121 gtatcgaaca ggcagaaatg cacgggcgga acgagactca aagtacgcgg ttcttcgggg
     9181 ctggaaaaca gcatcagcgt gccggtgcgg gcgatgccgc attgcgcgcc gctgaagccc
     9241 gcattgatgt tcgtgaaaaa ctcggttttc caagtatcga tttcgcgctc gaagacaatc
     9301 ggttcgatat tgctgcccgc caatgcggca cgggcaattt gtccgtgttc ggtcgccaag
     9361 ggcagcagga tgtttttcaa acccttgcct tctgccgctt cgcggaaaac ctgcatccaa
     9421 ttgcttttcg tcacccaata aatttcggtt ttgaccgcgc gcattgcggc agcccaatgt
     9481 ttcagacgct cggcttcgct gtcccaagaa acgccctttt cgcggtaata atcgaaaacc
     9541 gcaggctctt ccatcggcaa ggcatcggct tttttcagtt ttgccaaaat attttcacgc
     9601 gcgctcatgc tttgcctccg gtgcgttcca acaagaagga tgcgatatgt ttcggacgcg
     9661 gcatatccgg ctcgtccttg gcgattttgc cgccgatgtt catcatacag ccgcagtccg
     9721 cgctgatgat ttcggttgcg ccggtttctt tcagcgcggc gactttgtcg gttaccatcg
     9781 cgccggaaat atcggcttgt ttgacggaga atgtgccgcc gaagccgcaa cattcgcttt
     9841 cgtggtcgtg gacgatgcgt tcgacgtttt ccataccgtc aatcagttgc cagcctgaaa
     9901 gatggacatt catttcgcgg cgggcggcgc aggaagtgtg aacggcgact ttgagcggtt
     9961 cgcccttgtc ttcgggtttg aaaccgatgg caagcaggaa atgggtaaac tcgatgatgc
    10021 ggccggcgca atccacagcc ctttcctcgt actcgctgcc tttaaacagc gtcggccaat
    10081 ggtgcttcat cataccgccg cacgaaccgg acggtacgac aatcggccac tcctcgggga
    10141 aaaggtcgag ttgcgctctg gcgacatcaa aggcttcggt cggatggccg gatgaatagg
    10201 cgggctgacc gcagcagctt tgcgccatcg ggaaatggac gcgtatgccc tgttgctcga
    10261 ttagggtaat ggcatccatg cctgcttcgg gcataaaaag atcaaggacg caagtgccga
    10321 aaaaatagac atcggtcgga ttgctgtcgt atcggatgat ttttggggga atggttgcgc
    10381 tcatgttttt tgataacggg aaacccgttt ttttctgtag aaaggtaagc gtttacttta
    10441 agtaattgac tgttgcgggt caagtctaat tttaaaaaat aatccggttt ttcttacaaa
    10501 ctgccccata acgcttactg taccttactc tgataatttt cgataataat tatcattaca
    10561 atgaaatgcc gattcgtttg cttgtgaaca ttcaggacgc cgactctgac ggcattcaga
    10621 cagcatctga aaacaataac ggcacaagga tggggtacaa tcgccctatg gaaaaaaaca
    10681 ccctatccgc ccgcgcacca tccccttggc tgccgcttct gctggcaatt gccattttta
    10741 tgcagatgtt ggatgcgacc attttaaata ccgcactgcc tgaaattgcc accgacctgg
    10801 acgaatcgcc tctggatatg caactggcag tcgttgccta tacgctgacg gttgccctgc
    10861 tgattccttt gagcggttat ttggcggaca ggttcggaac gaaaaaagtc tttttcggtt
    10921 cgattgccgt ttttatactc ggatcggcat tgtgcgccgc atcgggttcg ctgtttgaat
    10981 tgacgctttc ccgtgtcgtt cagggcatcg gcggttcgat gctggttccg ataccgcgtc
    11041 tgaccatctt gcgtatgtac gacaagtcca agctgctcaa tgccatcaat tatgcggtca
    11101 tgcctgcatt aatcgggccg gttttagggc ctttggcggg cggttatttg gtcgaatacg
    11161 cttcgtggca ctggattttc ctgctcaacc tgcccatcgg tctgctgggt ttcatattgg
    11221 gacgcaacat catgcccgat attaaaggca gcaatatctc tttagacttc aaaggctatc
    11281 tgattttttc tgccgccgcg tgcctcttgt tactttcggc agaaagcctg tcgcacgcgc
    11341 tgcctccgta ttttgcactg ttgccgctgt gcggcggact gctgtttgca cgccgttatt
    11401 tccgacatat gaaaaccgcg tccaaaccga tttattccgc cgacctgttt ctgatacgca
    11461 ctttccgtct aggactggcg ggcaatctgt tcagccgtct cggcatcagc tcgattcctt
    11521 ttctgatgcc cctgatgttt caagtcgctt tcggcttcgg cgcaagcctg tcgggttggc
    11581 tggtcgcccc cgtcgccctg tcttcgctgc tggtcaaacc gctgattgca ccgctcatga
    11641 aacgtttcgg ctaccgcacg gtactgcttt ggaacaccaa gctgcttgcc gccttcatca
    11701 tgctgctcgc cctgcctgac ggaaactcgt cgctgtggat ttggattttc ctctcgctgg
    11761 cgatcggcgc gtgcaactcc ctgcagtttt ctgccatgaa tacactgacc ctcgccgatt
    11821 tgcgcccgca acagaccggc agcggcaaca gcctgatggc ggtcaaccaa cagcttgcca
    11881 tcagcatggg cattgttgtc ggcgcattaa tccttaaaaa ctggacattt ctgataccgg
    11941 cttcttcagg tctgcattcc gccttccgta tgaccctgct cagcatcggc ggcatcaccc
    12001 ttgcctcgtc gttggttttc aagcgtctgc acgtttcaga cggcgcaaac ctgacacgga
    12061 acacactgtc ctaaagcggt ccgcacgcaa aacttttacc cgtttcaacg tttggattat
    12121 gattccgcac atccatgcgc gccaacccca aaacacaggc aatgccgtct gaaaccatat
    12181 ccctgatgaa aacacgcagc ctaatttccc ttttatgcct ccttctctgt tcatgttctt
    12241 catggttgcc cccactggaa gaacggacgg aaagccgtca tttcaatact tccaaacccg
    12301 tccgcctgga caacatcctg caaatccggc acacccctca taccaacggg ctatccgata
    12361 tctatctgct gaacgacccc cacgaagcct ttgccgcccg cgccgccctt atcgaatctg
    12421 ccgaacacag cctcgatttg caatactaca tctggcgcaa cgacatttcc ggccgactgc
    12481 tgttcaacct cgtgtacctt gccgcagaac gcggtgtgcg cgtacgcctg ctgttggacg
    12541 acaacaacac gcgcggattg gacgacctcc tgctcgccct cgacagccat cccaatatcg
    12601 aagtgcgcct gttcaacccc ttcgtcttcc gcaaatggcg cgcactcggc tacctgactg
    12661 acttcccccg cctcaaccgc cgcatgcaca acaaatcctt taccgccgac aaccgcgcca
    12721 ccatactcgg cggacgcaat atcggcgacg aatacttcaa agtcggtgag gacaccgttt
    12781 tcgccgacct ggacatcctc gccaccggca gcgtcgtcgg cgaagtatcg cacgacttcg
    12841 accgctactg ggcaagccat tccgcccaca acgccacgcg catcatccgc agcggcgaca
    12901 tcggcaaggg tcttcaagca ctcggataca acgacgaaac gtccagacac gcgctcctgc
    12961 gctaccgcga aaccgtcgaa cagtcgcccc tctaccaaaa aatacagaca ggatgcatcg
    13021 actggcagag cgtccgaacc cgcctcatca gcgacgaccc tgcaaaagga ctcgaccgcg
    13081 accgccgcaa actgccgatt gccgagcggc tgcaagacgc gctcaaacag cccgaaaaaa
    13141 gcgtctatct ggtttcaccc tatttcgtcc ccacaaaatc cggcacagac gcactggcaa
    13201 aactggtgca ggacggcata gacgttaccg tcctgaccaa ctcgctacag gcgaccgacg
    13261 ttgccgccgt ccattccggc tatgtcaaat accgaaaacc gctgctcaaa gccggcatca
    13321 aactctacga gctgcaaccc aaccatgccg tccctgccac aaaagacaaa ggcctgaccg
    13381 gcagctccgt aaccagcctg cacgccaaaa ccttcattgt ggacggcaaa cgcatcttca
    13441 tcggttcgtt caacctcgac ccccgttccg cgcgtctcaa caccgaaatg ggcgttgtta
    13501 tcgaaagccc caaaatcgca gaacagatgg agcgcaccct tgccgatacc acacccgaat
    13561 acgcctaccg cgttaccctc gacaggcaca accgcctgca atggcacgat cccgccaccc
    13621 gaaaaaccta cccgaacgaa cccgaagcca aactttggaa acgcatcgcc gcaaaaatcc
    13681 tatccctgct gcccatagaa agtttattat agaaatatag cggattaaca aaaaccagta
    13741 cggcgttgcc tcgccttagc tcaaagagaa cgattctcta aggtgctgaa gcaccaagtg
    13801 aatcggttcc gtactattcg tactgtctgc ggcttcgtcg ccttgtcctg atttttgtta
    13861 atccactata ccgtctgaaa caccttcaga cggatatccg aacccgcaaa ggaaaaacca
    13921 tgtttccccc cgacaaaacc cttttcctct gtctcagcgc actgctcctc gcctcatgcg
    13981 gcacgacctc cggcaaacac cgccaaccga aacccaaaca gacagtccgg caaatccaag
    14041 ccgtccgcat cagccacatc gaccgcacac aaggctcgca ggaactcatg ctccacagcc
    14101 tcggactcat cggcacgccc tacaaatggg gcggcagcag caccgcaacc ggcttcgatt
    14161 gcagcggcat gattcaattc gtttacaaaa acgccctcaa cgtcaagctg ccgcgcaccg
    14221 cccgcgacat ggcggcggca agccgcaaaa tccccgacag ccgccttaag gccggcgacc
    14281 tcgtattctt caacaccggc ggcgcacacc gctactcaca cgtcggactc tatatcggca
    14341 acggcgaatt catccatgcc cccagcagcg gcaaaaccat ccgaaccgaa aaactctcca
    14401 caccgtttta cgccaaaaac tacctcggcg cacatacttt ttttacagaa tgagccgccc
    14461 gccgcgctgc gccggaatcg cggcaaaatg ccgccttatt ccgctgtttc ggtcagcgat
    14521 gagaacacgt cgaaataagt cgggaaggtt ttgtgggtgc atttcggatc gttgatgacg
    14581 acgggtacgc ccaacagcga aaccagcgag aaacacatcg ccatgcggtg gtcgtcgtac
    14641 gtgtcgatga cggcgtcggg tgtcggcgtt tcgggcgggg tgatgtgaat tgcttcggct
    14701 tcttcgacga cttttgcccc gagtttgcgc aactcgtttg ccatcgcggc gatgcggtcg
    14761 gtttctttga cgcgccacga accgatgttg cgcagcgtgc aggtttgccc tgtagcaagc
    14821 gcgacgatgg cgagggtcat cgcggcatcg ggaatatggt tcgcatccaa atcaaaggcc
    14881 cggacggcac gttctttcgg gcgcgagact tcgacgaagt tttcgcccca aaccacgtcc
    14941 gcaccgattt tttccagctc gcgggcaaag gcgacatcgc cctgtatgct gtttgcgccg
    15001 ataccggtaa cgcggacggg cgtggcagca atcaaaccgg ctgcgaggaa gtaggacgcg
    15061 ctggaggcat cgccttcgac gtgcaagtgt tcgggcgcgt ggtagcgcgc atcggcggga
    15121 attttgaaga cgcggtagcc ttcattgata acctgtacgc cgaattgcgc catcagtttt
    15181 aaagtaatgt cgatataggg cttggaaatt aactcgccga ccatacggat ttcaaacgcc
    15241 tgcccggtca gcggcaacgc cattaaaagg gcggtcagaa actggctgga cacattgcct
    15301 ttaatcggaa tcacgcgctc gccgcggtct tggcgttcgc cgatatgaag cggcggatag
    15361 tgttccttgc cgagatattc gacatcggcg ccggcaatcc gcagtgcatc ggccaaatcg
    15421 ccgatggggc gttcgtgcat acgcgcaacg ccgtgcaaat gataatcgcc gcccaaaacg
    15481 gcaagtgcgg cggtcagcgg gcggaacgcc gtgcccgcgt tgcccaaaaa caaatcggca
    15541 gtgcggttgg ggaagcgtcc tcctgtgccg tgcactttca gacggtcttc ggcaagatat
    15601 tcgatttgaa cgccgagttt atcgagtgct tcgagcatac ggtcggtatc gtcggatttg
    15661 agcagggaat ggatttcgca agcattgtcg gacaaggcgg caagcagcag ggtgcggttg
    15721 ctgatgcttt tggagccggg cagggcgacg gtggaaggtt tgagacgggc gacggggagg
    15781 cggacggatt cggtcatggc aaaacgtcaa tatagggata aaaacagcct gcattatact
    15841 ggtgcaaatg ccgtctgaaa aatctcaggt ttggcatttt cggttttaaa gtccgtaaat
    15901 gtggtttttt atgccgaaaa ttgattattt ttaaattttt tgtttctaaa atttctttgt
    15961 cggcatattt tcagcttttg ttgcggacat ggcgcgtttg cggacggtac ggtacgattg
    16021 ccaatttcat agaatttggt agaatagccg ctgttcaacg acagacaagc cgccgatttt
    16081 ccgggcggct tgtattttta ttttaatatc cggacgcaca aaacaagacg gtacgcggta
    16141 tgtttgctgc cgcaaaccgg tgtgccggaa tatggagaaa aaagaccgat gcaaaaaatc
    16201 cccctgaccg tacgcggtgc ggaattgctg aaacaggaat tgcagcagct caaaagcgtg
    16261 gcgcgtcccg aagtgatcga agcgattgcc gaagcccgtt cgcacggcga tttgtccgaa
    16321 aacgccgaat atgaagccgc caaagaacgc caaggcttta tcgaaggccg catttccgag
    16381 ctggaacaca aactttccgt tgcccacatc atcaatccga ccgaaatcca cgccgaaggc
    16441 aaaatcgtgt tcggtacgac ggttacgctg gaagatttgg aaacggaaga acacgttacc
    16501 taccaaattg tcggcgaaga cgaagccgac atcaaacagg gcaaaatcta tgtcggctca
    16561 cccatcgccc gcgccttaat cggcaaggaa gagggggata cggcggaagt ccaagccccg
    16621 ggcggcgtgc gcgaatacga cattatcgaa gtccgatata tttgattcgg cttgatttcg
    16681 atacacccga cacacgcagg aaattatagt ggattaacaa aaatcaggac aaggcgacga
    16741 agccgcagac agtacaaata gtacggaatc gattcacttg gtgcttcagc accttagaga
    16801 atcgttctct ttgagctaag gcgaggcaac gccgtactgg tttttgttaa tccactataa
    16861 cagcaaccct gtcgccgtca ttcccgcaaa agcgggaatc taggacgcag ggttaagaaa
    16921 acctgcatcc cgtcattccc tcaaaaacag aaaaccaaaa tcagaaacct aaaatcccgt
    16981 cattcccgcg aaagcgggaa tctagaatct cggactttca gataatcttt gaatattgct
    17041 gttgttctaa ggtctagatt cccgcctgcg cgggaatgac gaatccatcc gcacggaaac
    17101 ctgcaccgcg tcattcccac gaacccacat cccgtcatta ccacgaaagc gggaatctag
    17161 gacgcagggt taagaaaacc tacatcccgt cattcccgca aaagcgggaa tccaaacttg
    17221 tccgcacgga aacttatcgg ataaaacggt ttcttagatt ccacgttcta gattcccgcc
    17281 tgcgcgggaa tgacggcaga acggtttctg ttttttccga taaattccta aaactcaaaa
    17341 tttcatcctt cctacaaaaa cagaaaacca aaatcagaaa cctaaaattc gtcattcccg
    17401 caaaagcg
//
LOCUS       DAXISH010000047        17097 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.047, whole genome shotgun sequence.
ACCESSION   DAXISH010000047 DAXISH010000000
VERSION     DAXISH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 17097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17097
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.047"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..1991
                     /locus_tag="ACFOV4_001511"
     CDS             <1..1991
                     /locus_tag="ACFOV4_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_180374913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HFC7619490.1"
                     /translation="FIISLFFSILYTSPLLAVDYVYDNSKLTNEQIDRLKKLRDKSSE
                     YWKQETYLLKPTNGSSQNSLKVPALYSKTHQFKNINNSKKISFYDKEYTEDYLVGFAR
                     GFGVEKRNGEEEKTLQQYFKDCVNTGNSNNDKCEQPSFENSGPRLIKSDIFALAPQIK
                     NSHINSEILSVGNYIEWLRPTLNKLPSWQEHLYSGLDPFHYIEVTDNSHVIGQTISLD
                     EFRLENSLWEPRWDSDVGELKTTNADIRFNTKSESLLVKEDYAGGARFRFAYDLKDKV
                     SETPVLTFEKNITGTSDIIFENPIDDLKSLDGHQIIKVNGTADKHAFRLSGKHQKGIY
                     TLSLQQRPEGFFTKVQERDDISIYAQQAQAANTLFALRLNDKNSDIFDRTLPRKGLWL
                     RVIDGHSNQWVQGKTAPVEGYRKGVQLGGEVFTWQNESNQLSVGLMSGQAEQRSTFRN
                     PDTDNLTTGNVKGFGAGIYATWHQLQDKQTGAYADSWVQYQRFRHRINTEDATERFTS
                     KGITASIEAGYNALLAEHFTKKGNSLRVYLQPQAQLTYLGVNGKFSDSENAHVNLLGS
                     RQLQTRVGVQAKAQFSLYKNIAIEPFAAVNALYHNKPFGVEIDGERRVINNKTAIESQ
                     LGVAVKIKSHLTLQASFNRQTSKYHQAKQGALNLQWTF"
     gene            complement(2172..3539)
                     /locus_tag="ACFOV4_001512"
     CDS             complement(2172..3539)
                     /locus_tag="ACFOV4_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HFC7619491.1"
                     /translation="MPDLHTEFSRLLPADEIAELSPTLLKDQRNRFTSAPDIILQPRS
                     VESVQTIMRFCYEHRIPVTPQGGNTGLCGAAVSENGVLLNLSKLNRIRSINLSDNCIT
                     VEAGSVLQTVQQAAEASNRLFPLSLASEGSCQIGGNIACNAGGLNVLRYGTMRDLIIG
                     LEVVLPNGELVSHLHPLHKNTTGYDLRHLFIGSEGTLGIITAATLKLFARPSDKATAW
                     VGIPDIESAVRLLTETQAHFAERLCSFELIGRFAAELSSEFSKFPLPTHSEWHILLEL
                     TDSLPDSNLDDRLVEFLYKKGFTDSVLAQSEQERIHMWALRENISASQRKLGTSIKHD
                     IAVPIGRVADFVRRCAKDLEQNFKGIQIVCFGHLGDGSLHYNTFLPEILSNEVYRYEN
                     DINDAVYRNVLACNGTIAAEHGIGIIKKQWLDKVRTPAEIALMKSIKQHLDPYNIMNP
                     GKLLP"
     gene            complement(3649..3915)
                     /locus_tag="ACFOV4_001513"
     CDS             complement(3649..3915)
                     /locus_tag="ACFOV4_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619492.1"
                     /translation="MKKSLFAAALLSLVLAACGGEKAAEAPATEAPAAEAPAAEAAAT
                     EAPAAEAPTAEAAATEAPAAEAPAAEAAATEAPAAEAPAAEAAK"
     gene            4388..4870
                     /locus_tag="ACFOV4_001514"
     CDS             4388..4870
                     /locus_tag="ACFOV4_001514"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC7619493.1"
                     /translation="MAIVKNSVVSLHYEMYDANNQLLDKTEEPIAYLHGGYDGIFPLV
                     EEALHGKDAGDTVDVALSPDDAFGEQDSELVRIEDVGVFPVEVEVGMMFEADDPETGD
                     VVVYRVTDVADGKAVVDGNHPLAGMKIRFKATVESVRDASDEEIAHGHVHGPHGHHHH
                     "
     gene            4957..5769
                     /gene="hpnC"
                     /locus_tag="ACFOV4_001515"
     CDS             4957..5769
                     /gene="hpnC"
                     /locus_tag="ACFOV4_001515"
                     /EC_number="2.5.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="squalene synthase HpnC"
                     /protein_id="HFC7619494.1"
                     /translation="MSVGHYENFPVGSLILPRRLRKPVHAVYAFARTADDMADEGSMP
                     SEARLAGLDALRRELDVLASGGRSAHPLIARLDAEAVVPFGLDLQPFYDLLSAFSQDV
                     VKTRYAHFGELADYCRRSANPVGRIMLALYGKTDAVCVAQSDGICTALQLVNFWQDVA
                     VDWQKGRVYIPQDDLLKFGVSEGQIAEGRADAAFQRLMAYECRRAFRMLKAGSPLARE
                     LKGRIGLELRMIVLGAQLILQKLDACRYDVFAQRPVLDKKDWLIMLKRALWK"
     gene            complement(5840..6310)
                     /locus_tag="ACFOV4_001516"
     CDS             complement(5840..6310)
                     /locus_tag="ACFOV4_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1841 family protein"
                     /protein_id="HFC7619495.1"
                     /translation="MYDVNTHDVRRFFARVWQQRLNPLQLSVLEQKALRIIEAHPEYH
                     RYLERIEDHLDTDWLPENGESNPFLHMSLHLSVQEQAGIDQPHGIRAIHDTLCAKRGW
                     LEAEHEMMEALAETLWTAQRYGTGLDVNFYMTRLRKLIGLGAEDQARLNPHEIA"
     gene            6401..8242
                     /locus_tag="ACFOV4_001517"
     CDS             6401..8242
                     /locus_tag="ACFOV4_001517"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0047134 - protein-disulfide reductase
                     (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HFC7619496.1"
                     /translation="MQTNYLSETDSIMKKLICLFAVFLMLCGRAFALDANDLLPPEKA
                     FVPELAVADDGVNVRFRIADGYYMYQAKIVGKTDPADLLGQPSFSKGEEKEDEFFGRQ
                     TVYHHEAQVAFPYAKAVGEPYKLVLTYQGCAEAGVCYPPVDTEFDISGNGTYHPQTDE
                     PASAKDRFLQPSSQNGSGALPPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTA
                     CMYPLLPIVSSIVVGDKKAGKARAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQ
                     QAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRLSGGKIVSVFIMGILSA
                     LIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIAIGTFGGHILPRAGD
                     WMNAVKYAFGFILLAVAVYLATPHLPYYLVVALYTLLMLVPACMLLVNGRRQKRRPKA
                     VAFALGGILLIGGAWFGWQGANGKTTALHHFLTLNPPAEAGKSSEHGKMFADTAALKA
                     AMDTALKEHPDKPVVLDFYADWCISCKEMAAYTLNQPEVHQAVDMERFFQIDVTANTP
                     EHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFVKADKFIEWYEQNR"
     gene            complement(8758..9954)
                     /locus_tag="ACFOV4_001518"
     CDS             complement(8758..9954)
                     /locus_tag="ACFOV4_001518"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HFC7619497.1"
                     /translation="MSQKLILVLNCGSSSLKGAVLDNGSGEVLLSCLAEKLNLPDAYI
                     TFKVNGEKHKVDLSAHPDHTGAVEALMEELKAHGLDSRIGAIGHRVVSGGELYSESIL
                     VDDEVIAGIEKCIPLAPLHNPAHLLGLRAAQSIFKDLPNVVVFDTSFHQTMPEVAYKY
                     AVPQELYEKYGLRRYGAHGTSYRFVADETARFLGKDKKDLRMVIAHLGNGASITAVAN
                     GESRDTSMGLTPLEGLVMGTRSGDIDPSVFGFLAENANMTIAQITEMLNKKSGLLGIS
                     GLSNDCRTIEEEAAKGHKGAKLALDMFIYRLAKYIGSMAVAAGGLDALVFTGGIGENS
                     DIIRERVIGYLGFLGLNIDQEANLKARFGNAGVITTADSKAVAVVIPTNEELMIAHDT
                     ARLSGL"
     gene            10305..10604
                     /locus_tag="ACFOV4_001519"
     CDS             10305..10604
                     /locus_tag="ACFOV4_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619498.1"
                     /translation="MHYFSIHDQSGRHIGFFILLADDESEARPQSGRFAVKLEGGMEN
                     HVLSPFGQTEIPQYWRVVKDRIELFFDEAPVGTLRNEYLTVSGQTFVLNDLTGNM"
     gene            10604..10789
                     /gene="ccoS"
                     /locus_tag="ACFOV4_001520"
     CDS             10604..10789
                     /gene="ccoS"
                     /locus_tag="ACFOV4_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008535 - respiratory chain complex IV
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome oxidase assembly protein
                     CcoS"
                     /protein_id="HFC7619499.1"
                     /translation="MESMFILVPISIILAFVIGWFFWWSGKNGQFDDLEGPAHRILMD
                     DDSTSKLIEKERENDVR"
     gene            10779..12089
                     /locus_tag="ACFOV4_001521"
     CDS             10779..12089
                     /locus_tag="ACFOV4_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC7619500.1"
                     /translation="MYAKKGGLGLVKSRRFAPLFATQFLGAFNDNVFKTALFVMIGFY
                     GLGQNGFLPAGQMLNLGALLFILPYFLFSSLSGQLGNKFDKAVLARWVKVLEMIIMAV
                     AAYGFYIRSAPLLLACLFCMGAQSTLFGPLKYAILPDYLDDKELMMGNSLIESGTFVA
                     ILFGQILGTAVAGVPPYIVGILVLLVAVGGTVGSLFMPSVPAKAADTQIEWNIVRGTK
                     SLLRETVRYKPVFTAIIGISWFWFVGAVYTTQLPTFTQIHLGGNDNVFNLMLALFSIG
                     IAAGSVLCAKFSRERLMLAWVTVGALGLTVCGLVLVWLTHGHRFEGLNGIFWFLSQGW
                     AYPVMAVMTLIGFFGGFFSVPLYTWLQTASSETFRARAVAANNIVNGIFMVSAAVLSA
                     VLLFLFDSISLLYLIVALGNIPLSVFLIKRERRFLGAAAIRKKP"
     gene            12247..12981
                     /gene="dnaQ"
                     /locus_tag="ACFOV4_001522"
     CDS             12247..12981
                     /gene="dnaQ"
                     /locus_tag="ACFOV4_001522"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HFC7619501.1"
                     /translation="MIQRQIILDTETTGLYADGGDRLVEFAGLEMVNRQMTDKNLHLY
                     VHPERDMPEEAARVHGLTIEVLEGKNAPPFAEVGRQIADFLRGAELIIHNAKFDVGFL
                     NMEFRRMGLPTVEELGCTVTDTLAMAREMFPGQKASLDALCNRFSVDRSKRVLHGALI
                     DCELLGKVYLAMTRRQFDLMGEAEEEEPAAKPVASAEMKLGAKLKVIKADEAELAAHG
                     QYLDGLGEACIWRKEAVPSENGGADA"
     gene            12978..13667
                     /gene="ispD"
                     /locus_tag="ACFOV4_001523"
     CDS             12978..13667
                     /gene="ispD"
                     /locus_tag="ACFOV4_001523"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFC7619502.1"
                     /translation="MKRKNIALIPAAGIGARFGADKPKQYVEIGSKTVLEHTIGIFER
                     HEGVDLTVVVVSPEDTFADKVQTAFPQVRVWKNGGQTRAETVRNGVAKLLEIGLAAET
                     DNILVHDAARCCLPSEALTRLIEQAGNAAEGGILAIPVADTLKRADGGNISATVERTS
                     LWQAQTPQLFRAGLLHRALAAENLDGITDEASAVEKLGIRPLLVQGDARNLKLTQPQD
                     AYIVRLLLDAV"
     gene            13699..14181
                     /gene="ispF"
                     /locus_tag="ACFOV4_001524"
     CDS             13699..14181
                     /gene="ispF"
                     /locus_tag="ACFOV4_001524"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HFC7619503.1"
                     /translation="MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALL
                     HAVTDALLGAAGLGDIGSHFPDTASEFKDADSRALLRDAYRSVQAKGWHVVNVDTTVI
                     AQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVRI
                     "
     gene            14258..14929
                     /gene="rpiA"
                     /locus_tag="ACFOV4_001525"
     CDS             14258..14929
                     /gene="rpiA"
                     /locus_tag="ACFOV4_001525"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFC7619504.1"
                     /translation="MTTQDELKRIAAEKAVEFVPENEYIGIGTGSTINFFIEALGKSG
                     KKIKGAVSTSKKSSELLAQYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHL
                     NEKIVASASEKFVCIADESKYVSRLGKFPLPVEVVESARSLVSRKLLAMGGQPELRIG
                     YTTFYGNQIVDVHGLNIDQPLTMEDEINKITGVLENGIFARDAADVLILGTEEGAKVI
                     YPCQG"
     gene            14998..15669
                     /locus_tag="ACFOV4_001526"
     CDS             14998..15669
                     /locus_tag="ACFOV4_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HFC7619505.1"
                     /translation="MQIKKIMKWLPVALSLLGALGYTGYGSEAVRTAVAVLDVLGAAG
                     DAGSDAPARRRASAKSGHRYTGTVSKVYDGDTLHVIDGDGAKHKIRMAYIDAPEMKQA
                     YGTRSRDNLRAAAEGRKVSVRVFDTDRYQREVAQVSVGKTDLNLMQVQDGAAWHYKSY
                     AKEQQDKADFADYADAQIQAERERKGLWKAKNPQAPWAYRRAGRSGGGNKDWTDSVGE
                     WLGIW"
     gene            15685..15864
                     /locus_tag="ACFOV4_001527"
     CDS             15685..15864
                     /locus_tag="ACFOV4_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003708735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619506.1"
                     /translation="MNGKCRLKTARPAFLRRRATAVCRDKKVQAAVFTVKWRIILQRR
                     QFRRFLIRTVYGFSF"
     gene            15848..16594
                     /locus_tag="ACFOV4_001528"
     CDS             15848..16594
                     /locus_tag="ACFOV4_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFC7619507.1"
                     /translation="MDFRFDIIYEYRWMFLYGALTTLGLTVVATAGGSVLGLLLALAR
                     LIHLEKAGAPMRVLAWALRKVSLLYVTLFRGTPLFVQIVIWAYVWFPFFVHPSDGILV
                     SGEAAIALRRGYGPLIAGSLALIANSGAYICEIFRAGIQSIDKGQMEAARSLGLTYPQ
                     AMRYVILPQALRRMLPPLASEFITLLKDSSLLSVIAVAELAYVQNTITGRYSVYEEPL
                     YTVALIYLLMTTFLGWIFLRLEKRYNPQHR"
     gene            complement(16870..>17097)
                     /locus_tag="ACFOV4_001529"
     CDS             complement(16870..>17097)
                     /locus_tag="ACFOV4_001529"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619508.1"
                     /translation="NPKIQNHRKLSKKQKPSAVVPAKAGIRNRKPQKFIGKTETQKQR
                     KPNGQDSRLRGNDGSYITQKIETKQMGFPLA"
BASE COUNT         4002 a         3928 c         4860 g         4307 t
ORIGIN      
        1 catttattat aagtctattt ttttctattc tttatacctc tccgcttttg gctgttgatt
       61 acgtttacga caattctaaa ttaacaaatg agcaaattga tcgcttaaaa aaacttagag
      121 ataaaagcag cgaatactgg aaacaagaaa cttatcttct aaaaccgacg aatggtagct
      181 ctcagaactc tctcaaagtt cccgcactat actctaaaac acaccaattc aaaaacatca
      241 acaactcaaa aaagatttct ttttatgaca aggaatacac tgaagattac cttgttggct
      301 tcgcccgagg tttcggggtt gaaaaaagga atggggaaga agaaaaaaca ctccagcaat
      361 attttaagga ctgtgtaaat actgggaatt ccaataatga taagtgtgaa caaccatcct
      421 tcgaaaactc tggcccaaga ttaataaaga gcgatatttt cgccttagct ccacaaataa
      481 aaaatagcca tatcaacagc gaaattttat ctgtaggtaa ttatatcgaa tggcttcgcc
      541 caacacttaa taagcttcct agttggcaag agcatctcta ttctggttta gatccattcc
      601 actatattga ggttacagac aactcacacg ttatcggaca aacaattagt ttggatgaat
      661 tccgcttaga aaattctctc tgggaacccc gttgggattc tgatgttggg gaattaaaaa
      721 caacgaatgc agacatccgt tttaatacta aaagtgaaag tttactcgta aaagaagatt
      781 atgctggcgg agctcgtttt cgttttgctt acgatctaaa agataaagtc tctgaaacac
      841 cagttttaac ttttgaaaaa aatataactg gcacttccga catcatcttc gaaaatccaa
      901 tagacgattt aaaaagtctc gacgggcatc aaattatcaa agtaaatggc acagcagata
      961 aacacgcatt ccgtctttct ggcaaacacc aaaagggaat ttatacgctt tctttacaac
     1021 aacgcccaga aggctttttt accaaagtgc aagaacgcga tgatatttcg atttatgcac
     1081 aacaggctca agccgccaat accttattcg ccttgcgttt gaacgacaaa aacagcgata
     1141 tttttgaccg cactttacca cgcaaaggct tgtggttgcg tgtgattgac ggacattcca
     1201 accaatgggt gcaaggcaaa acagcacctg tagaaggcta tcgtaaaggt gtgcaactcg
     1261 gtggcgaagt attcacatgg caaaacgaaa gtaatcaact ttccgttggc ttaatgagcg
     1321 gacaagcaga acaacgcagc actttccgca atccagatac agacaatctt acaacgggaa
     1381 atgtgaaagg ctttggggcg ggcatttatg ccacttggca tcagcttcag gacaaacaga
     1441 caggtgcgta tgcggatagc tgggtacaat atcaacgctt ccgccaccgc attaacactg
     1501 aagatgctac agaacgtttt acttcaaaag gtattaccgc ctcaattgaa gcgggttaca
     1561 atgctttatt ggcagaacac ttcactaaaa agggcaacag ccttcgtgtt tacctacaac
     1621 cacaggcaca attgacttat ttgggggtaa acggaaaatt cagcgatagc gaaaatgccc
     1681 acgtgaattt acttggctcc cgccaattac aaactcgggt tggcgttcaa gctaaagctc
     1741 aattttcact ctataaaaat atcgctattg aacctttcgc cgctgtgaac gcgctttacc
     1801 acaacaaacc tttcggtgtg gaaatagacg gagagcgtcg agtgataaac aataagacgg
     1861 caattgagag ccaattaggt gtagcagtga aaatcaaatc tcacttaact ttacaagcct
     1921 cattcaaccg ccaaacaagc aaatatcatc aggctaaaca aggtgcgttg aatttgcagt
     1981 ggacgtttta agttaagttg taacaaaata aaatcggcag ggaaattcac tgccgatttt
     2041 tttattttaa aaatgcggtc atttttcgtg tcatttccac caatttttta ccgcactcac
     2101 gagctcgcgc taaaccgaca atcggatcta ttgtcccttt ctttgttgtg tatgcaaatc
     2161 agaaatgccg gttacggaag cagtttgccc ggattcataa tgttatatgg atcaaggtgt
     2221 tgtttgatgc ttttcatcag ggcgatttcg gcaggcgtgc gtactttgtc cagccactgt
     2281 tttttgatga tacctatgcc gtgttcggcg gcaatcgtgc cgttgcaggc aagaacgttg
     2341 cgataaactg cgtcgttgat gtcgttttcg taacgataga cttcattgct gaggatttcg
     2401 ggcaggaaag tattgtagtg caggctgccg tcgccaagat gtccgaagca gacgatttgt
     2461 atgcctttaa aattctgttc caaatctttg gcgcaccggc ggacaaagtc ggcaacgcgt
     2521 ccgataggaa cggcaatatc gtgtttgatg ctggtgccca gtttgcgttg ggaggcggag
     2581 atgttttcgc gcaatgccca catatggata cgttcttgtt cgctttgtgc caatacgctg
     2641 tcggtaaatc cttttttata aagaaattcg acgagccgat catcaagatt gctgtcgggt
     2701 aatgagtcgg tcaactcaag taaaatatgc cattctgaat gtgtcggcag ggggaatttg
     2761 ctgaattcgg aagacaactc ggcggcaaaa cggccgatca gctcaaaact gcataggcgt
     2821 tcggcaaagt gagcttgggt ttcggtcagc aggcggacgg cggattcgat gtcgggtatg
     2881 ccgacccatg ccgttgcctt gtccgaggga cgggcaaaaa gcttgagtgt ggcggcagtg
     2941 atgatgccca gtgtgccttc gctgccgata aacagatggc gcaggtcgta gccggtggtg
     3001 tttttatgca ggggatggag atgggaaacc agctcgccgt tggggaggac gacttccaaa
     3061 ccgataatca ggtcgcgcat cgtgccgtaa cgcaatacgt tcaaacctcc ggcattgcag
     3121 gcgatgttgc cgccgatttg acaggagcct tcgctggcga gactgagtgg gaacagcctg
     3181 tttgaggctt cggctgcctg ttggacggtt tggagtacgg aacctgcttc gacggttatg
     3241 cagttgtctg acaaattgat gctgcggatg cggttgagtt tggaaaggtt cagcaatacg
     3301 ccgttttccg atactgccgc gccgcacaaa ccggtattgc cgccttgcgg cgtaaccgga
     3361 atacggtgtt cgtaacaaaa acgcataatg gtttgcacgc tttcaacgct gcgcggctgc
     3421 aaaatgatgt ctggtgcaga cgtaaagcgg ttgcgctggt cttttaaaag cgtcggagaa
     3481 agttcggcaa tttcatctgc cggcaggagt cgggaaaatt cggtatgaag gtcaggcatg
     3541 tttgtcggaa gggtagggag aagattgagg aagggaatct gatgccgtct gaaaaatcaa
     3601 aaaagcagga tactgaacgt atcctgcttt tttgcaagcg gaaaatgctt attttgcagc
     3661 ttcggcagca ggagcttcag cggcaggtgc ttcggtagcg gcagcttcag cagcgggagc
     3721 ttcggcggca ggtgcttcag tagcggcagc ttcagcagtg ggagcttcgg cggcaggtgc
     3781 ttcagtagcg gcagcttcag cagcgggagc ttcggcggca ggtgcttcgg tagcgggagc
     3841 ttcagcggct ttttcaccgc cgcaggctgc caggaccaaa gacaacaaag cagcggcaaa
     3901 cagggatttt ttcattttag taacctttag aaccaattta aattattgaa acaaataggt
     3961 ctttatcgac catactacaa accgggttgg aaattcatcg ctgaatttgc gtaattatgc
     4021 actatggaat aagggattgc aatgtcgtac agatgggaaa aaggtttgaa tgaaaagttt
     4081 tctggcgggc ggattgataa atcctgtaaa acggttttgc tgttaaaaat tcgataggga
     4141 taaatattat agagattaat ataatttcag tatcttgtat gatttattaa ggcggattgg
     4201 gaaagtcggc agacaggtcg gaatggtttt aataatgttg taaaaaagtt acatcgcaat
     4261 aaaataacaa aaatttacat tgaaatatgt gctgtacagt ttatgaacag gttaacggta
     4321 atcggccggc gcggcggttg tgttagaatg cgcctgtaat caatctgctg ttcctgaaag
     4381 gacaaatatg gctatcgtga agaattccgt ggtttcgctg cattatgaga tgtatgatgc
     4441 caacaatcag cttttggaca aaaccgaaga accgattgcg tatctgcacg gcggttacga
     4501 cggcattttc cctttggtgg aagaggcgtt gcacggtaag gatgccggcg atacggtcga
     4561 tgtggcgctt tcgcccgacg atgcgttcgg cgagcaggat tcggagttgg ttcgtattga
     4621 agatgtgggc gtgttccctg ttgaagtcga agtcggcatg atgtttgaag ccgacgatcc
     4681 tgaaaccggc gatgttgtcg tctatcgtgt aaccgatgtt gccgacggca aggcggtggt
     4741 ggacggcaac catcctttgg caggcatgaa aatccgtttt aaggctacgg ttgaaagcgt
     4801 gcgcgatgca tccgatgagg aaatcgcaca cggtcatgtc cacggcccgc acggtcatca
     4861 ccaccactga ttgccggcag cttggaggta tctgatgccg tctgaaaagg gtttgttccg
     4921 tttcagacgg cattttgttt gatggatgga gaaggtatgt cggttgggca ttatgaaaat
     4981 tttcccgtcg gttcgctgat tttgccgcgc aggttgagga agccggttca tgcggtgtat
     5041 gcgtttgcac ggacggcgga cgatatggcg gacgagggca gtatgccgtc tgaagccagg
     5101 ttggcggggt tggatgcttt gcggcgcgag ttggacgtgt tggcatcggg cggccggtcg
     5161 gcgcatcctt tgattgcacg attggatgcc gaggcggttg tgccgttcgg tttggatttg
     5221 cagccgtttt atgatttgct ttcggcgttt tcgcaggacg tggttaaaac gcggtacgcg
     5281 catttcggcg aactggccga ttactgccgg cgttccgcca accctgtcgg acgcattatg
     5341 ctggctttgt acgggaaaac ggatgcggtg tgcgtggcgc aaagcgacgg catctgtacg
     5401 gctttgcaac tggtgaattt ttggcaggat gtggctgtgg attggcaaaa gggcagggtt
     5461 tatattccgc aggacgattt gttgaaattc ggtgtttccg aaggacagat tgcggagggt
     5521 agggcggatg cggcgtttca gcggctgatg gcgtatgagt gccggcgcgc atttcgtatg
     5581 ctgaaggcgg gttcgccttt agcgcgcgaa ttgaaagggc gtatcggttt ggaactccgt
     5641 atgattgtgt tgggggcgca gttgattttg cagaaactgg acgcgtgccg atacgatgtg
     5701 tttgcacaac gccccgtttt ggataagaag gattggttga ttatgctgaa acgcgcgttg
     5761 tggaaatgat gggggaaatg catgccgtct gaaaggggtt gttccgcttc agatggcatt
     5821 ttgcaggcgg ttggtgtggt caggcgattt catgcgggtt caacctggct tgatcttctg
     5881 cacccaagcc gatgagtttg cgcagtcggg tcatgtagaa attgacatcc aaaccggtgc
     5941 cgtagcgttg cgccgtccac agtgtttccg ccagtgcctc catcatttcg tgttcggctt
     6001 ccagccagcc gcgtttggcg cacagggtgt cgtggattgc gcgtatgccg tgcggctggt
     6061 ctatgcccgc ctgttcttgg acggacaaat gcagcgacat atgcaggaag gggttgcttt
     6121 cgccgttttc gggtagccag tcggtgtcca gatggtcttc gatgcgttcg agataacggt
     6181 ggtattcggg atgggcttcg ataatgcgga gggctttctg ttccagtacg ctcagttgca
     6241 gcggattgag ccgctgctgc cacacgcggg cgaaaaagcg gcggacatcg tgggtattga
     6301 catcgtacat ggcgggttcg gtaagatgtt tatggaaata ggttcggata atggcgggtt
     6361 ttacataaat taaatcccac cgtcaacctt accatttata atgcagacaa attatttgtc
     6421 tgaaacggat tcgattatga aaaaactgat ttgcctgttc gccgtatttt tgatgttgtg
     6481 cggacgagct ttcgcgctgg atgcgaacga tctgctgccg ccggaaaagg cattcgtgcc
     6541 ggagcttgcc gttgccgacg acggtgtgaa cgtccgtttc aggattgccg acggatacta
     6601 tatgtatcag gcgaaaatcg tcggcaagac cgatccggcg gatttgttgg gacagccttc
     6661 tttcagcaag ggcgaagaga aggaagacga gtttttcggc aggcagacgg tttaccatca
     6721 cgaagcgcag gttgcctttc cttatgcaaa ggctgtcggc gaaccgtata aattggtttt
     6781 gacctatcag ggctgtgccg aagccggcgt gtgctatccg cccgtggata ccgagtttga
     6841 tatttccggc aacggcactt accatccgca aaccgacgaa ccggcatccg ccaaagaccg
     6901 ctttttgcag ccttcctctc aaaacggcag cggggcgttg ccgcccccga agggggatga
     6961 gggcggcgac agccgtttca agctgtcttg ggatacgctc aacgccaatc ttttggcgtt
     7021 ttttctcgcc ggtttgggtc tgagttttac cgcctgtatg tatcccctgt tgccgattgt
     7081 ttccagtatt gtggtcggcg acaaaaaggc gggcaaggcg cgggcgtttg tgctgtccgt
     7141 cgtttatgtt cagggtttgg ctctgactta tacgctggtc ggcattgttg ccggactgac
     7201 gggcgcgctg ctgaccgtat ggttgcagca ggcttgggtg gtgttggcgg catcggcttt
     7261 aatggtcgtc ttggcactgt ctatgttcgg gctgttcaac atccagcttc ccaacgccgt
     7321 gcagtcgtat ttccaaaacc agagcagcag gctttcaggc ggtaaaatcg tttccgtctt
     7381 tattatgggc atattgtccg cgctgattgt cgggccgtgc gtcgccccgc cgctggcatt
     7441 tgctttgggc tacatcggtc agacgggcga tgcggtttta ggcggtttgg cactttacac
     7501 tttggcgttg ggcaccggcg ttccgctgat tgccatcggc acgttcggcg ggcatatcct
     7561 gcctagggca ggcgattgga tgaatgccgt caaatacgct ttcggcttta tcctgcttgc
     7621 cgtcgccgtt tacctcgcca cgccgcactt gccctattat ctcgtcgtcg cgctgtacac
     7681 gctgctgatg ctggttcctg cctgtatgct gctggtcaac ggacgcaggc agaaacgccg
     7741 tccgaaagct gtggcattcg cattgggcgg catattgctg ataggcggcg cgtggttcgg
     7801 ctggcagggc gcaaacggca aaacgaccgc gctgcaccat ttcctgaccc tcaatccacc
     7861 agccgaagca ggcaaatctt cggaacacgg caaaatgttt gccgatactg ccgcgctgaa
     7921 ggcagcgatg gatacggcgt tgaaagaaca tcccgacaaa cccgtcgttt tggattttta
     7981 tgccgactgg tgtatttcct gcaaagaaat ggcggcatac acgctcaatc agccggaagt
     8041 gcatcaggcg gttgatatgg aacgcttttt ccaaatcgac gtaaccgcca acacgcctga
     8101 acatcaggcg ttgttgaaag aatacggtct gttcgggccg ccgggcgtgt ttgtcgtccg
     8161 ctccgacggc agccgcagcg agccgctgct gggttttgtc aaagcagaca agtttatcga
     8221 gtggtatgaa caaaaccgct gattccgatg tttcaaatgc cgtctgaagt tctcagacgg
     8281 catttttgtc agaaaggaaa acggcaatat ccactataca cacggaagca gtctaaagat
     8341 gtgaaaaccg tgtgtataag ttagtttgcg tattgaaatt aaaagataaa aatacgatga
     8401 ttaaaaaata ggcataagaa aagataaaca cagccggtgt ttgccggtgt gtgtatcttt
     8461 tgtggaaaaa catcttaatg tcatgtattt tatggaaaat aataacatga ttaaaaaata
     8521 gtcaatcatt atagtggatt aaatttaaat caggacaagg cgacgaagcc gcagacagta
     8581 cagatagtac ggcaaggcga ggcaacgccg tactgattta aatttaatcc actataaggt
     8641 tcaggtaagc ggctgcaacc gtcaatgtct gaaaagaggc agtgctgttt aagcatggaa
     8701 agccggataa aaaaaactgc ctccgtttcc ggaggcagtt cgtgtgcgga taaaacctta
     8761 cagaccgctc aaacgggcag tgtcgtgggc aatcatcagc tcttcgttgg tcggaatgac
     8821 cacggcaacg gctttgctgt cggcagtggt aatcacgccg gcgttgccga agcgggcttt
     8881 caggttggct tcttggtcga tgttcagacc gaggaagccc aagtagccga tcacgcgttc
     8941 gcggatgatg tcggagtttt cgccgatgcc gccggtaaag accagtgcgt ccaaaccgcc
     9001 tgcggcaacc gccatactgc cgatgtattt ggcaaggcgg tagataaaca tatccaaggc
     9061 caatttcgcg cctttatgcc ccttggcggc ttcttcttca atggtgcggc agtcgttgga
     9121 caggccggaa atgccgagca gaccggattt tttgttcagc atttcagtga tttgggcgat
     9181 ggtcatattg gcgttttcgg cgagaaagcc gaatacggaa ggatcgatgt cgccgctgcg
     9241 cgtacccatt accagccctt ccagcggggt caggcccata ctggtgtcgc gcgattcgcc
     9301 gttggcgacg gcggtaatgg acgcgccgtt gcccaagtgg gcaatgacca tacgcaggtc
     9361 ttttttgtct ttgccgagga agcgcgcggt ttcgtcggcg acgaagcggt agctggtacc
     9421 gtgcgcgccg taacggcgca ggccgtattt ttcatacaac tcctgcggaa cggcgtattt
     9481 gtaggcgact tcgggcatgg tttggtggaa ggaggtatcg aatacgacga cgttgggcag
     9541 gtctttgaaa atgctttgcg cggcacgcag gcccaagagg tgggcggggt tgtgcagggg
     9601 ggcgagcggg atgcattttt cgatgccggc aatgacttcg tcgtcaacga ggatggattc
     9661 gctgtacagt tcgccgccgc tgacgacgcg gtggccgatg gcgccgatgc ggctgtcgag
     9721 gccgtgggct ttgagttctt ccatcagggc ttcgaccgcg ccggtgtggt cgggatgtgc
     9781 ggacagatcg actttgtgtt tttcgccgtt tactttgaat gtgatgtagg catcgggcag
     9841 gttgagtttt tcggcaaggc agctgagcag gacttcgccg ctgccgttat ccaggaccgc
     9901 gcctttgagg gacgagctgc cgcagttcaa aaccaagatc aatttttggg acattttctt
     9961 actccggaaa gtttcagacg gcattggaat cggacacgga tactaaccgg attcgtgccg
    10021 aatccgtttt gccttcctag gcgggaaagt agtggggccg tctgaaacgg ttgataaaag
    10081 aagcaggcta ttctaacaaa aaatctttgc aattgcttgg cttaatcggg cgtttgcgtg
    10141 aaaatggcgg aagtcgggta ttttgacgga aaaaaggggg atatgcggtt tgccggtgtt
    10201 ttcggctggg ggagggagaa tttctttgca ttcttcccgt ccaaactggt acattcgccc
    10261 tgtttttagt tggtgtcgtc tgaaaaaagg cgggtgggaa atttatgcat tatttcagta
    10321 ttcatgacca atcgggacgg catataggct ttttcatcct gcttgccgac gacgaatcgg
    10381 aagcacggcc gcaaagcggg cgttttgccg tcaaacttga aggcggaatg gaaaatcatg
    10441 tcctgtcgcc gttcggtcag acggaaattc cccaatattg gcgcgtggtc aaagaccgta
    10501 tcgagctgtt ttttgacgaa gctcccgtcg gaactttgcg taacgaatat ctgaccgtgt
    10561 cggggcagac ttttgttttg aacgatttga cagggaatat gtgatggaaa gcatgtttat
    10621 attggtgccc atcagcatta ttttggcgtt tgtcatcggc tggttttttt ggtggtcggg
    10681 caaaaacggg cagtttgacg acttggaagg gccggcgcac cgcatcctga tggatgatga
    10741 ttcgacaagt aaactgattg aaaaagagag ggaaaacgat gtacgctaaa aaaggcggtt
    10801 tgggactggt taaaagccgc cgtttcgcac ctcttttcgc tacgcagttt ctcggcgcgt
    10861 tcaacgacaa tgtgttcaaa accgcgctgt ttgtgatgat tgggttttac ggtttggggc
    10921 aaaacggctt cctgcctgcc ggacagatgt tgaacttggg cgcgttgttg tttattttgc
    10981 cgtatttcct gttttcctcg ctgtcggggc agttgggtaa caaattcgac aaggccgttt
    11041 tggcgcgttg ggtcaaggtg ctggaaatga tcattatggc ggtggcggca tacgggtttt
    11101 atatccggtc tgccccgctg cttttggcgt gtctgttttg catgggcgcg caatcgacgc
    11161 tgttcgggcc gctgaaatac gccatcctgc ccgattatct cgacgacaaa gagttgatga
    11221 tgggcaacag cctgattgaa tcgggtacgt ttgtcgccat cctgttcggt cagattttgg
    11281 gaacggcggt ggcaggtgta ccgccttata ttgtcgggat actggttttg ctggtcgccg
    11341 tcggaggcac ggtcggcagc ctgtttatgc cgtccgtccc cgccaaggct gccgataccc
    11401 aaattgagtg gaatattgtc cgtggcacaa aatccctgct tcgtgaaacg gtgcggtaca
    11461 aacccgtctt taccgctatt atcggtattt cgtggttttg gtttgtcggc gcggtctata
    11521 ctacgcaact gccgaccttt acccaaatcc atttgggcgg caacgacaat gttttcaacc
    11581 tgatgcttgc cctgttttcc atcggtattg ccgccggttc ggtactgtgt gccaagttca
    11641 gcagggaacg gctgatgttg gcttgggtaa cggttggtgc gttgggtttg acggtttgcg
    11701 gcctggtttt ggtgtggctg acgcacggac accgttttga agggctgaac ggcatttttt
    11761 ggtttttatc gcaaggatgg gcatatcccg tgatggcggt gatgacgctg atcggctttt
    11821 tcggcggatt tttctccgtt ccgctctata cttggctgca aaccgccagt agcgagactt
    11881 tccgcgcccg cgccgttgcc gccaacaata tcgttaacgg tatttttatg gtttccgccg
    11941 ccgttttgag cgcggtgttg ctgtttttgt ttgacagcat ttccttgttg tatctgattg
    12001 tcgctttggg caatattccg ttgtcggtat ttttgattaa gcgcgaaagg cggtttttag
    12061 gcgcggcggc aatcaggaaa aaaccttgaa tgccgtctga aaaaattgtc cccaaaatac
    12121 acaatccgcc tgcccaatgt tgtgaacaca ctgtgaataa gtgggtttgt gcattgaaat
    12181 gaaaacagaa aaatatattg cttaaaaaat agtcagcaga tggaaaattt gaagaaagaa
    12241 gcagacatga ttcaacgcca aatcatcctc gataccgaaa ccaccggtct gtatgccgac
    12301 ggcggcgacc gcttggtcga gtttgccggt ttagaaatgg tcaaccgcca aatgaccgac
    12361 aaaaacctgc acctctatgt ccaccccgag cgcgatatgc ccgaagaggc ggcgagggtg
    12421 cacggtctga cgatagaggt tttggaaggg aaaaacgcgc cgccgtttgc agaggtcggc
    12481 aggcagattg ccgatttcct gcgcggtgcg gaactgatta tccacaatgc caaattcgac
    12541 gtgggcttcc tcaatatgga gttccgccgg atggggctgc cgactgtcga ggaactcggc
    12601 tgtaccgtta ccgataccct ggcgatggcg cgcgaaatgt tccccgggca gaaagccagc
    12661 ctggatgcct tgtgcaaccg tttttccgtc gaccgcagca agcgcgtcct gcacggcgca
    12721 ttgatcgact gcgaactttt gggcaaagtc tatcttgcta tgacgcggcg gcagttcgac
    12781 ctgatggggg aggccgagga ggaagagccg gcagccaaac ctgttgcatc tgccgaaatg
    12841 aaactcggtg ccaaactgaa agtgattaag gcggatgaag ccgaactggc ggcgcacggg
    12901 caatatttgg acggcttggg cgaagcctgt atctggcgca aggaagccgt gccgtcggaa
    12961 aacggcgggg cggacgcatg aagcgcaaaa atatcgcgct gattcccgcc gccggcatcg
    13021 gggcgcgttt cggtgcggac aaacctaagc agtatgtcga aatcggaagc aaaaccgttt
    13081 tagaacatac gattgggatt tttgaacggc atgagggcgt cgatttgacc gtcgttgtcg
    13141 tctcgcccga agacacgttt gccgataagg ttcagacggc atttccacag gttcgggtgt
    13201 ggaaaaacgg cggacagacc cgcgccgaaa ccgtccgaaa cggtgtggca aaactgttgg
    13261 aaatcggttt ggcggcggaa accgacaata ttctggtaca cgatgccgcg cgttgctgcc
    13321 tgccgtctga agctttgacg cggttgatag aacaggcggg caacgctgcc gaaggtggga
    13381 ttttggcaat tcccgttgcc gatacgctca agcgcgcgga cggtgggaac attagtgcaa
    13441 ccgtcgagcg gacgagcctt tggcaggcac aaacgccgca gcttttccgc gccgggctgc
    13501 tgcaccgcgc attggctgcg gaaaacttgg acggcattac cgatgaagcg tccgccgtcg
    13561 aaaaattggg catccgccct ttgctggtgc agggcgacgc gcgcaatttg aaactgacgc
    13621 agccgcagga cgcatacatc gtcaggctgc tgctcgatgc cgtctgaact tcaattcaaa
    13681 ccatcaggaa cacaaacgat gacgaacatc cgtatcggac agggctacga tgtccaccaa
    13741 ctgaccgaag gcagaaagct gatacttggc ggagttgaaa tcccatttga aaaagggctg
    13801 ctcggacact ccgatgccga tgcgctgctg cacgccgtta ccgacgcgct gcttggcgcg
    13861 gcaggtttgg gcgatatcgg cagccatttc cccgataccg cctcagagtt taaagatgcg
    13921 gacagccgcg ccctgctgcg cgatgcctat cggagcgttc aagctaaggg gtggcatgtc
    13981 gtcaatgtcg atacgaccgt gattgcacag aaacccaaac tcgcgccgca cattccgcaa
    14041 atgcgtgcca acatcgccgc cgatttgggc atagacattt cgtgcgtcaa catcaaaggt
    14101 aaaaccaacg aaaaactcgg ctatctcgga cggatggaag gcatagaggc gcaggcggcg
    14161 gtattgctgg tacggatttg aacgcggcgg gcaggacgtg caaaaaaatg ttaagatgac
    14221 ggctgtttgt tgatacggtt tcccaaagga caaaaatatg acgacacaag acgaactcaa
    14281 gcgcatcgcc gccgaaaaag cagtcgaatt cgtacccgaa aacgaataca tcggcatcgg
    14341 taccggttcg accatcaact ttttcatcga agccttgggt aagagcggca aaaaaatcaa
    14401 aggcgcggta tctacttcca aaaaatccag tgaactgctt gcccaatatg atattcccgt
    14461 cgtttccctg aacgaagtat cggggttggc ggtctatatt gacggtgcgg atgaagtgaa
    14521 ccacgccctg caaatgatta aaggcggcgg cggcgcacac ctcaacgaaa aaatcgtcgc
    14581 cagcgcatcc gaaaaattcg tctgcattgc ggatgaaagc aaatatgttt cacgtttggg
    14641 caaattccct ctgcctgtgg aagtcgtcga aagcgcgcgc tctcttgttt cgcgcaaact
    14701 gctcgctatg ggcggacagc ccgaactgcg tatcggctac accacgtttt acggcaacca
    14761 aatcgtcgat gtccacggct tgaatatcga tcagccgctg acgatggaag acgaaatcaa
    14821 caaaatcacc ggcgtactcg aaaacggaat attcgcccgc gatgccgccg atgtgttgat
    14881 tttggggacg gaagagggtg cgaaagtcat ctatccctgc caagggtaat cctgacgtta
    14941 agatgccgtc tgaaatccgg ttcagagatg ttcagacggc atcggcattt gaaaaatatg
    15001 cagattaaaa aaatcatgaa atggcttccc gtcgccctgt cgcttttggg cgcgttgggt
    15061 tatacgggat acggcagcga ggcggtgcgg acggcggttg ccgtactcga cgtactcggc
    15121 gcggcagggg acgcgggttc cgacgcgccc gctcgccgcc gagcatcggc gaaatccggc
    15181 caccgctaca caggcacggt gtccaaagtc tatgacggcg acacccttca cgttatcgac
    15241 ggcgacggcg cgaaacacaa aatccggatg gcgtatatcg acgcgccgga gatgaaacag
    15301 gcttacggca cgcgttcgcg cgacaacctg cgtgcggcgg cggaaggcag gaaagtcagc
    15361 gtccgcgtgt tcgacaccga ccgctaccag cgcgaagtgg cgcaggtttc tgtcggcaaa
    15421 accgatttga acctgatgca ggtgcaggac ggggcggcgt ggcattataa aagttatgct
    15481 aaagaacagc aggataaggc ggattttgcc gattatgccg acgctcaaat tcaggcggaa
    15541 agggaacgca aaggattgtg gaaagctaaa aatccgcaag cgccgtgggc gtaccgccgg
    15601 gcaggcagga gcggcggggg caataaggat tggacggatt ccgtgggcga atggttgggc
    15661 atttggtaaa gacaccgcac ggctttgaac ggcaaatgcc gtctgaaaac cgcgcgccct
    15721 gcatttttgc ggagacgcgc aaccgccgtc tgccgcgata aaaaagttca ggcggcggtt
    15781 tttacggtaa aatggcggat tattttgcaa cggcggcagt tccgccggtt tttgatacgg
    15841 acggtttatg gattttcgtt ttgacattat ttacgaatac cgctggatgt ttctttacgg
    15901 cgcactgacg accttggggc tgacggtcgt ggcgacggcg ggcggttcgg tattgggtct
    15961 gttgttggcg ttggcgcgcc tgattcactt ggaaaaagcc ggtgcgccga tgcgcgtgct
    16021 ggcgtgggcg ttgcgtaagg tttcgctgct gtatgttacg ctgttccggg gtacgccgct
    16081 gtttgtgcag attgtgattt gggcgtatgt gtggtttccg tttttcgtcc atccttcaga
    16141 cggcattttg gtcagcggcg aggcggcaat cgcgctgcgt cgcggatacg ggccgctgat
    16201 tgccggttct ttggcactga tcgccaactc gggggcgtat atctgtgaga ttttccgcgc
    16261 gggcatccag tctatagaca aaggacagat ggaggcggcg cgttctttgg ggctgaccta
    16321 tccgcaggcg atgcgctatg tgattctgcc gcaggcattg cgccgcatgc tgccgccttt
    16381 ggcgagcgag ttcatcacgc tcttgaaaga cagctcgctg ctgtcggtca ttgctgtggc
    16441 ggagttggcg tatgttcaga atacgattac gggccggtat tcggtttatg aagaaccgct
    16501 ttacaccgtc gccctgattt atctgttgat gacgactttc ttaggctgga tattcctgcg
    16561 tttggaaaaa cgttacaatc cgcaacaccg ctgattggag tcatatcaac aaaaagctgc
    16621 ccgggtattc atttgaggca gcttttttgt ggcaaattta tcgtggatta acaaaaacca
    16681 gtacggcgtt gcctcgcctt agctcaaaga gaacgattct ctaaggtgct gaagccccga
    16741 gtgaatcggt tccgtactat ttgtactgtc tgcggcttcg tcgcctgttc tgatttttgt
    16801 taatccacta taaattcaaa gagaaaaagc tatgccgtct gaaagtcttt cagacggcat
    16861 ctgtcagcct cacgcaagag ggaatcccat ctgtttggtt tcaatttttt gggtgatgta
    16921 tgagccgtca ttcccgcgca ggcgggaatc ctgtccgttc ggtttccgtt gtttttgagt
    16981 ttcggttttc ccgataaatt tttgtggttt ccggttccgg attcccgctt tcgcgggaac
    17041 gacggcggat ggtttctgtt tttttgataa cttcctgtga ttttggattt ttggatt
//
LOCUS       DAXISH010000048        16179 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.048, whole genome shotgun sequence.
ACCESSION   DAXISH010000048 DAXISH010000000
VERSION     DAXISH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 16179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16179
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.048"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            754..5406
                     /gene="iga"
                     /locus_tag="ACFOV4_001530"
     CDS             754..5406
                     /gene="iga"
                     /locus_tag="ACFOV4_001530"
                     /EC_number="3.4.21.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IgA-specific serine endopeptidase
                     autotransporter"
                     /protein_id="HFC7619509.1"
                     /translation="MKTKRFKINAISLSIFLAYALTPYSEAALVRDDVDYQIFRDFAE
                     NKGKFFVGATDLSVKNKQGQNIGNALSNVPMIDFSVADVNRRTLTVIDPQYAVSVKHV
                     KGDEISYYGHHNGHLDVSNDENEYRSVAQNDYEPNKNWHHGNQGRLEDYNMARLNKFV
                     TEVAPIAPTSAGGGVETYKDKNRFSEFVRVGAGTQFEYNSRYNMTELSRAYRYAIAGT
                     PYQDVNVTSNLNQEGLIGFGDNSKHHSPEKLKEVLSQNALTNYAVLGDSGSPLFAYDK
                     QEKRWVFLGAYDYWAGYQKNSWQEWNIYKKEFADEIKQRDNAGTIKGYGEHHWKTTGT
                     NSHIGSTAVRLAGNERGANNGQNVTFENNGTLVLDQNINQGAGGLFFKGDYTVKGINN
                     DITWLGAGIDVADGKKVVWQVKNPNGDRLAKIGKGTLEINGTGVNQGQLKVGDGTVIL
                     NQKADSNQKVQAFSQVGIVSGRGTLVLNSSNQINPDNLYFGFRGGRLDANGNDLTFEH
                     IRNVDEGARIVNHNTGHTSTITLTGKSLITNPNSLSVHSIQNDYDEDDYSYYYRPRRP
                     IPQGKDLYYKNYRYYALKSGGSVNAPMPENGQTENNDWILMGSTQEEAKKNAMNHKNN
                     QRISGFSGFFGEENGKGHNGALNLNFNGKSAQNRFLLTGGTNLNGKISVTQGNVLLSG
                     RPTPHARDFVNKSSARKDAHFSKNNEVVFEDDWINRTFKATEIAVNQSASFSSGRNVS
                     DITANITATDNAKVNLGYKNGDEVCVRSDYTGYVTCNTGNLSDKALNSFGATQINGNV
                     NLSQNAALTLGKAALWGQIQGQGNSRVSLNQHSKWHLTGDSQVHNLSLADSHIHLNNA
                     SDAQSANKYHTLKINHLSGNGHFHYLTHLAKNLGDKVLVKESASGHYQLHVQDKTGEP
                     NQEGLNLFDASSVRDRSHLSVSLANNHVDLGALRYTIKTENGITRLYNPYAENRRRVK
                     PAPSPATNTASQAQTDSAQIAKPQNIVVAPPSPQANQAEEAKRQQAKAEQVKRQQAEA
                     EKVAHQKAEEAKRQQDALARQQAEQERQRLEAERQAAEIAKQKAEAEEAKRRAAEIAE
                     QKAAAEEAKRQAAELARQQEEARKAAELAAKQKAETERKAAEIAEQKAEAEREAAELA
                     KQKAEEEGRQAAQSQPKRRNRRAIPPELSSDATTRALPRIARNSNPDASDYEEIPLDA
                     LEDEDVSESVDTSDKQPQDNTELHEKVETVSLQPRAAQPRAQAAAQPQAQAVAQADAV
                     STNTNSALSDAMASTQSILLDTGASLTRHIAQKSRADAEKNSVWMSNIGYGRDYASAQ
                     YRRFSSKRTQTQIGIDRSLSENMQIGGVLTYSDSQHTFDQASGKNTFVQANLYGKYYL
                     NDAWYVAGDIGAGSLRSRLQTQQKANFNRTSIQTGLTLGNTLKINQFEIVPSAGIRYS
                     RLSSADYKLGNDSVKVSSMSVKTLTAGLDFAYRFKVGNLTVKPLLSAAYFANYGKGGV
                     NVGGNSFAYKADNQQQYSAGAALLYRNVTLNVNGSITKGKQLEKQKSGQIKIQIRF"
     gene            complement(5585..6787)
                     /gene="trpB"
                     /locus_tag="ACFOV4_001531"
     CDS             complement(5585..6787)
                     /gene="trpB"
                     /locus_tag="ACFOV4_001531"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HFC7619510.1"
                     /translation="MKNYHAPDEKGFFGEHGGLFVSETLIPALQELADAYKAAKNDPS
                     FWEEFHRDLKHYVGRPSPVYHAARLSEHLGGAQIWLKREDLNHTGAHKVNNTIGQALL
                     AKRMGKKRVIAETGAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGAN
                     VVGVDSGSRTLKDAMNEAMREWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAK
                     EQMLEAIGRQPDVAVACVGGGSNAIGLFHPYIGEENVRLVGVEAGGLGVNTPDHAAPI
                     TSGSPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHSHLHDIKRVEYTVAK
                     DDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPKMGKDQVILVNLSGRGDKDINTV
                     AKLKGIKL"
     gene            complement(6870..7559)
                     /locus_tag="ACFOV4_001532"
     CDS             complement(6870..7559)
                     /locus_tag="ACFOV4_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFC7619511.1"
                     /translation="MLFEGLPCLAVWCKNRLSAVLPVGGLNVSENLLEIETHPFDSVL
                     PPKAAVMMMGTFPPKEDKRAMQFHYPNFQNDMWRVYGLVFFNDAAHFQRLSEKAFDAE
                     KIKAFLHERGIASCPTVLKAAREHGNASDKFLKVVETVDLAAVLAKIPECRHICTTGG
                     KATEILLDIQGGGIKMPKTGETVPFPFAGRDLTLTRLPSTSRAYPLSLAKKAAVYRAF
                     FEMAGLCEKQL"
     gene            7756..8535
                     /gene="rsmA"
                     /locus_tag="ACFOV4_001533"
     CDS             7756..8535
                     /gene="rsmA"
                     /locus_tag="ACFOV4_001533"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFC7619512.1"
                     /translation="MKEHKARKRFGQNFLQDTRIISDIVNAVRPQADDVVIEIGPGLA
                     AITEPLAKKLNRLHVVEIDRDIVCRLKTLPFADKLVIHEGDVLQFDFNGIAGKKKIVG
                     NLPYNISTPLLFKLAEVADDVVDMHFMLQKEVVDRMVAAPKSNDYGRLGVMLQYFFDM
                     EMLIDVPPESFDPAPKVDSAVVRMIPVKHRIGKADDFEHFAKLVKLAFHQRRKTIRNN
                     LKELAGDDDLQAVGINPQDRAEHIAPEKYVALSNYLAGKAV"
     gene            8708..9436
                     /locus_tag="ACFOV4_001534"
     CDS             8708..9436
                     /locus_tag="ACFOV4_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFC7619513.1"
                     /translation="MIKFKNVHKHFKDLHVINGVNLEIKKGEVVVVCGPSGSGKSTLI
                     RTVNQLESIESGEIWVDGVNVADPKTDLNKIREEVGFVFQSFNLYPHLTVLENITLAP
                     MKVKGQNAEQAEKKAMELLERVGLAHKKDAFPSQLSGGQQQRVAIARGLAMEPRVMLF
                     DEPTSALDPEMVGEVLKVMKDLAESGMTMMCVTHEMGFAREVADRVIFVDKGQILEDE
                     TPEAFFTNPKHERAKQFLQQVMTH"
     gene            9509..9868
                     /locus_tag="ACFOV4_001535"
     CDS             9509..9868
                     /locus_tag="ACFOV4_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619514.1"
                     /translation="MYFVDRTAVVLKPTVRFLEWLKSTDENMPDLTIEQLRANCSVFL
                     VPQFDEPEAVVSYFDERYRQIFEAELAGWDIDKDKWPQDMGLKAFWEFFDIEIHDMVL
                     DMEEADLNITPVFDNMM"
     gene            9873..10319
                     /locus_tag="ACFOV4_001536"
     CDS             9873..10319
                     /locus_tag="ACFOV4_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HFC7619515.1"
                     /translation="MRAFQTALRPSRILNILTVSLHSASLAVCLTWFYGRMMWFGLAA
                     LAASYAYSLRITNLKHRHAITAITIDRDGQAEIVSGKEKTAKAATLAGSSMVTPYALF
                     LQWDTGGKTVRHCIMPDMTDKESYRKLKVWVLWRQPKKTAETDTSD"
     gene            10350..11624
                     /gene="folC"
                     /locus_tag="ACFOV4_001537"
     CDS             10350..11624
                     /gene="folC"
                     /locus_tag="ACFOV4_001537"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HFC7619516.1"
                     /translation="MKTLQDWLSHLETAHSGGLIDMGLERTSEVKKRMKLEPQCPVVV
                     VAGTNGKGSVCAYLTQIYKQAGYKTGTLTSPHLLRYNERIAINAEPVSDDTIIASFER
                     IEAARSEISLTYFEFNTLAAVDIFMREQVDVMILEVGLGGRLDAVNAFDGDCAVVTSV
                     DLDHQAFLGDTVEQVGFEKAGVFRSGKPAICGQNPAPESLLSHAEAIGAKLLMVQRDF
                     EFHAMENIQWNYRFRPQHSDDPARNRNALPFPALRGTYQLSNAACTLTVLECLNAKLP
                     VDIGAIKRGLLLVENPGRFQVLPGRPLTVLDVGHNPHAARALRRSLINLAFAQKRTAV
                     FSMLSDKDIDGVLETVKDQFDEWYIAPLDVPRGMTLESLQNKLHEHSIENIQTFAAVR
                     EAYRAAASKAGENDRIVVFGSFHTVADVMSVL"
     gene            11637..12635
                     /gene="ftsN"
                     /locus_tag="ACFOV4_001538"
     CDS             11637..12635
                     /gene="ftsN"
                     /locus_tag="ACFOV4_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HFC7619517.1"
                     /translation="MSENKQNEVLSGYEQLKRRNRRRLVTASCLVAASCILLAAALSS
                     GPAEQTAGETSGVENKAAGAAQTPALKSAADKPQDLAGEDKPSAADSEISEPENVGAP
                     LVLINDRLEDSNIKGLEASEKLQQAETAKTAPKQAKQRAAEKVPATADSTDTVAVEKP
                     KRTAETKPQKAERTAKAKPKAKETKTAEKVADKPKTAAEKTKPDTAKSDSAVKEAKKA
                     DKAESRKTAEKDRSDGKKHETAQKTDKADKTKTAEKEKSGKKAAIQAGYAEKERALSL
                     QRKMKAVGIDSTITEIMTDNGKVYRVKSSNYKNARDAERDLNKLRVHGIAGQVTNE"
     gene            12628..13125
                     /locus_tag="ACFOV4_001539"
     CDS             12628..13125
                     /locus_tag="ACFOV4_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFC7619518.1"
                     /translation="MNNLPVADLLVFAIIAACIVLSAMRGVIAEAGSMAAWVVSFFFA
                     KLFAAPFADLAFASFQPRLFALALSFISLFVIACLIQKMLRSLLTGAVSAVGLGFANR
                     ILGGVFGALKGVLIVTLLVMLASKTDLPDTEEWLQSYTIPFFVSLSEAVLNHSGGTAE
                     TPEDD"
     gene            13333..14877
                     /gene="purF"
                     /locus_tag="ACFOV4_001540"
     CDS             13333..14877
                     /gene="purF"
                     /locus_tag="ACFOV4_001540"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFC7619519.1"
                     /translation="MCGVLGLVSHEPVNQLLYDGLQMLQHRGQDAAGIATAEGGTFHM
                     HKGKGMVREVFRTRNMRDLVGNAGIAHVRYPTAGNAGSSAEAQPFYVSSPFGIVLAHN
                     GNLTNTAELYENVCNKHLRHVNTSSDSEVLLNVFAHELRREVSKNADPHRLNADNIFN
                     AVAEVHRLVRGAYGVVAMIAGYGMLAFRDPYGIRPLVLGSQTDNEGRKSYAVASESVA
                     FNALAYDLERDIRPGEAVFVGFDGTMIARQCSDRAKLSPCLFEYVYFARPDSVIDGVS
                     VYQSRLDMGVSLAEKIKRELPVDDIDVVMPIPDTSRPSAMELAVHLDKPYREGLIKNR
                     YIGRTFIMPGQATRKKSVRQKLSPMETEFAGKSVLLVDDSIVRGTTSREIVEMVRAAG
                     ARKVYIASAAPEVRYPNVYGIDMPTREELIANGRSAAEIAAEIGADGIVFQNLSDLEA
                     VVKALNPKIESFDSSCFNGIYQTGDIDDAYLDRLSAEKSGCGGLKIHPSRMEHSISIS
                     DAGDEE"
     gene            14977..15468
                     /gene="greB"
                     /locus_tag="ACFOV4_001541"
     CDS             14977..15468
                     /gene="greB"
                     /locus_tag="ACFOV4_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HFC7619520.1"
                     /translation="MSTETKNYITPAGWQALKDELYQLVNKERPEIVQIVNWAAGNGD
                     RSENGDYLYGKRRMREIDRRIRFLTKRLESAVVVDPELREATDQVFFGATVGLLRGDG
                     REQTVKIVGIDEIDTAQNKISWISPLARCLIKAREGDEVVLNTPEGREEIEILSVEYI
                     KID"
     gene            15527..16153
                     /locus_tag="ACFOV4_001542"
     CDS             15527..16153
                     /locus_tag="ACFOV4_001542"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HFC7619521.1"
                     /translation="MRKIRTKICGITTLEDAAAAAAAGADAVGLVFFQGSSRAVDIAR
                     AKKITAALPPFVSVVALFVNESAQNIRRILAEVPIHIIQFHGDEDDAFCRQFDRPYIK
                     AIRVQTASDIRNAADRFPDAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGG
                     LTPENVGEAVRITGAEAVDVSGGVEASKGKKDPAKVAAFIATANRLSR"
BASE COUNT         4488 a         4390 c         3948 g         3353 t
ORIGIN      
        1 ccgcagatgc ccgacggtct ttatagtgga ttaacaaaaa tcaggacaag gcggcgaagc
       61 tgcagacaat acaaacagta cggaaccgat tcacttggtg cttcagcacc ttagagaatc
      121 gttctcttta agctaagtcg aggcaacgct gtactggttt ttgttaatcc gctatattcc
      181 gccatctcta agatttacag cgatacacgg gggatttaag gaatgcccga accatcattc
      241 ccaccacttt tcgtcattcc cgctactttt cgtcattccc gccacttttc gtcattccca
      301 cgaaagtggg aatccagaat ctcggacttt cagataatct ttgaatattg ctgttgttct
      361 aaggtctaga ttcccgcctg cgcgggaatg acgaatccat ccgtacggaa acctgcaccg
      421 cgtcattccc acgaaccccc atctcgtcat taccacgaaa gcgggaatct aggacgcagg
      481 gttaagaaaa cctacatccc gtcattcccg cacaagcggg aatccaaaaa caaaaagtcg
      541 cagaaattta acggaagaac cgaaccccga aaatcggctt cccgccttcg cttgaataac
      601 agaacaaagg aagcggaaat aaaaacatcg ggattctttt tttaaattga caataaaaca
      661 ccaaaattaa tgatttacac aacaaaaaat agtcaacacc gccaaaccgg cgtaaaatac
      721 aagacattat cacccttaaa acggtaaaac cttatgaaaa ccaaacgttt taaaattaac
      781 gccatatcct tatccatctt tcttgcctat gcccttacgc catactcaga agcggcattg
      841 gtcagagacg atgtcgatta tcaaatattc cgtgactttg cagaaaacaa aggcaaattt
      901 tttgtcggcg caaccgattt atcagtgaaa aacaaacaag gtcaaaacat cggcaacgca
      961 ttatccaacg taccgatgat tgattttagc gttgcagatg tcaacagacg tacattaacc
     1021 gtcatcgatc cccagtatgc cgtcagcgtc aaacatgtaa aaggagacga aatctcttat
     1081 tacgggcatc acaatgggca cttagatgtt agcaatgatg aaaacgaata tcgttcagtt
     1141 gcacaaaatg actacgaacc aaataaaaat tggcatcacg gtaatcaagg tcgtcttgaa
     1201 gactacaaca tggcacgcct taataaattc gtaacagaag tcgcacctat tgcaccaacc
     1261 agtgcaggcg gcggcgttga aacctataaa gataaaaacc gtttttctga gtttgtgcga
     1321 gttggagcag gtacgcaatt tgaatataac agccgctaca atatgacaga gctttcacga
     1381 gcttatcgtt atgccattgc aggtacgcct tatcaagacg tgaatgtcac atcgaatcta
     1441 aatcaagaag gcttgattgg cttcggtgat aattcaaaac atcattcccc agaaaaactc
     1501 aaagaagttt tatctcaaaa cgcattgact aactatgctg tgttaggcga tagcggttca
     1561 ccattatttg cttatgataa acaagaaaaa cgctgggtct ttttaggtgc ttacgattat
     1621 tgggcaggct atcaaaaaaa ctcttggcaa gaatggaata tctataaaaa agaatttgca
     1681 gatgaaatca aacaacgcga taacgccggc accatcaaag gttatggcga acatcattgg
     1741 aaaaccacgg gcacaaacag ccatatcggt tcgacagcgg taaggcttgc cggcaatgaa
     1801 aggggtgcaa acaacggaca gaatgttacc tttgaaaaca acggcacttt ggtattggat
     1861 caaaacatca accaaggcgc gggcggtctg tttttcaaag gcgattacac agtcaaaggt
     1921 ataaataatg acatcacttg gctaggtgcg gggattgatg ttgccgacgg caaaaaagtc
     1981 gtttggcaag tcaaaaatcc gaatggcgac agattggcga aaatcggcaa aggcacatta
     2041 gaaataaacg gcacaggcgt taaccaaggg caattaaaag tcggcgacgg tacggttatt
     2101 ctgaatcaaa aagccgattc aaaccaaaaa gtccaggctt tctcccaagt cggcattgtc
     2161 agcggacgcg gtacattggt attaaatagt tcaaatcaga ttaatcccga taacctatat
     2221 ttcggtttcc gtggcggtcg tttggatgcc aatggcaatg acttgacttt tgaacacatc
     2281 cgcaacgtgg atgaaggcgc gcgcattgtc aaccacaaca caggccacac ctccacaatc
     2341 acgctaacgg gtaaatcttt aattaccaat ccgaacagcc tttcggtaca tagtatacaa
     2401 aatgactatg atgaagatga ttatagttat tattaccgac caaggcgacc catcccacaa
     2461 ggcaaagatc tttattacaa aaactatcgt tattacgccc taaaatccgg cggcagcgtg
     2521 aacgcaccga tgcccgaaaa cggacaaacg gaaaataacg actggatttt aatgggcagc
     2581 acacaagaag aagccaagaa aaacgcgatg aaccacaaaa acaatcagcg tattagcggt
     2641 tttagcggtt tctttggcga agaaaacgga aaaggacata acggtgcatt aaaccttaat
     2701 ttcaacggca aaagcgcgca aaaccgtttc ttgttaacag gtggcactaa tttaaacgga
     2761 aaaataagcg taactcaagg caatgtcttg ttatcaggtc gtccaacacc acacgcaaga
     2821 gattttgtga acaaatcttc agcccgaaaa gacgcacatt tctccaaaaa caatgaagtc
     2881 gtatttgaag acgactggat aaaccgcaca ttcaaagcca cagaaattgc ggttaatcaa
     2941 tccgcatcat tctcttccgg cagaaatgta tccgacatca ccgccaacat caccgcaaca
     3001 gacaacgcca aagtaaattt gggttacaaa aacggcgatg aggtttgcgt gcgctcggac
     3061 tataccggtt atgttacctg caacacaggc aacttatccg ataaggcttt aaacagcttt
     3121 ggagcgacac agattaacgg caatgtgaat ttgagtcaga atgcggcatt gactttgggc
     3181 aaggctgcat tatgggggca aattcaaggg caaggaaaca gccgtgtcag cctaaatcaa
     3241 catagcaaat ggcatttgac cggcgacagc caagtacaca atctgtcatt ggcggatagc
     3301 catattcatt tgaacaacgc ttccgacgcg caaagtgcaa ataaatacca cacgctcaaa
     3361 atcaatcatt tatccggtaa cgggcatttt cattatctga cgcacttggc aaaaaatctt
     3421 ggggataaag tgcttgtgaa ggaatccgca tccggtcatt atcagctcca tgttcaagat
     3481 aaaacaggcg aacccaatca ggaagggctg aatctctttg atgcatcatc cgtacgagac
     3541 cgatcgcacc tttccgtttc cttggcgaat aaccatgtag atttaggcgc attgcgttat
     3601 acaatcaaaa cagaaaatgg cattacccga ttgtacaatc cttatgccga gaaccgccgc
     3661 cgagtcaaac cggccccgtc tcctgccaca aacacggctt ctcaagcaca aacggacagt
     3721 gcacaaattg ccaagcctca aaatatcgtc gtcgcaccgc ctagcccgca ggcaaatcaa
     3781 gccgaagaag caaaacgcca acaagcaaaa gcggagcaag tgaagcgtca gcaagcagag
     3841 gcagaaaaag tcgcacatca aaaggctgaa gaagcgaaac gtcagcaaga tgcccttgcc
     3901 cgccaacaag cagagcaaga acgccaacga ttggaagccg aacgccaagc tgccgaaatt
     3961 gccaaacaaa aagcagaagc cgaagaagcg aaacgccgag ccgctgaaat tgccgagcaa
     4021 aaagcagctg ccgaagaagc aaaacgccaa gctgccgaac ttgcacgcca acaagaagaa
     4081 gcacgaaaag ctgcagagtt ggctgctaag caaaaagcgg aaactgaacg caaagcagca
     4141 gaaattgccg agcaaaaagc ggaagccgaa cgtgaagccg ccgaacttgc caagcaaaag
     4201 gcggaagaag aaggtcgcca agcagcacaa tctcaaccca aacgtcgtaa ccgcagggct
     4261 ataccaccgg aactgtcatc tgatgcaaca acccgagctt tgcctaggat agcgagaaat
     4321 tcaaatcctg atgccagcga ttatgaagaa atccccttgg atgcgttgga agatgaagat
     4381 gtatccgaat cggttgacac atcagacaaa cagcctcaag acaatacgga acttcatgaa
     4441 aaagttgaga cagtgagttt gcaaccaaga gccgctcagc cgcgagccca agccgccgcg
     4501 cagccgcaag cccaagccgt cgcgcaagcc gatgcagtca gcaccaatac caactcggct
     4561 ttatctgacg caatggcaag cacgcaatct atcttgttgg atacaggtgc ttcattaaca
     4621 cggcacattg cacaaaaatc acgtgctgat gccgaaaaaa acagcgtttg gatgtcgaac
     4681 atcggttatg gccgtgatta tgcttccgca caatatcgcc ggtttagttc gaaacgcacg
     4741 caaacacaaa tcggcattga ccgcagcttg tccgaaaata tgcagatagg cggcgtattg
     4801 acttactctg acagtcagca tacttttgat caggcgagcg gcaaaaatac ttttgtgcaa
     4861 gccaaccttt atggtaagta ttatttaaat gatgcttggt atgtggccgg cgatattggt
     4921 gcaggcagct tgagaagccg gttacaaaca cagcaaaaag caaactttaa ccgaacaagc
     4981 atccaaaccg gccttacttt gggcaatacg ctgaaaatca atcaattcga gattgtcccc
     5041 agtgcgggaa tccgttacag ccgcctgtca tctgcagatt acaagttggg taacgacagt
     5101 gttaaagtaa gttctatgtc agtgaaaaca ctgacggccg gactggattt tgcttatcgg
     5161 tttaaagtcg gcaaccttac cgtaaaaccc ttgttatctg cagcttactt tgccaattat
     5221 ggcaaaggcg gcgtgaatgt gggcggtaat tccttcgcct ataaagcaga taatcaacag
     5281 caatattcag caggtgccgc gttactgtac cgtaatgtta cattaaacgt aaatggcagt
     5341 attacaaaag gaaaacaatt ggaaaaacaa aaatccggac aaattaaaat acagattcgt
     5401 ttctaaaata ctaaattcat agcaaaataa aatgccgtct gaactcaggc ttcagacggc
     5461 atttttatag tggattaaca aaaatcagga caaggcgacg aagccgcaga cagtacagat
     5521 agtacggcaa ggcgaggcaa cgccgtactg gtttttgtta atccactata tcagacggac
     5581 gaggttacag tttaatccct ttgagcttcg cgacggtatt gatgtctttg tcgccacgac
     5641 cggataggtt gaccagaatc acttggtctt tgcccatttt cggcgcgttt ttcaccgccc
     5701 aagcaacggc gtggctggat tcgagcgcgg ggatgatgcc ctcgaagcgg cagagcaaat
     5761 caaaggcttc gagtgcttcg tcgtctttag cgacggtgta ttcgacgcgc ttgatgtcgt
     5821 gcagatggct gtgttccggg ccgatgccgg ggtaatccaa gcctgcggaa acagagtgtg
     5881 tacccaagac ttgaccgttt tcgtcctgca tcagatagct gcggaaaccg tgcaatacgc
     5941 caatcggtga gcccgaagta atcggcgcgg cgtgatcggg ggtgttcacg cccaaaccgc
     6001 cagcctccac gccgacgagg cgcacgtttt cttcgccgat atacgggtgg aacaaaccaa
     6061 tggcgttcga tccgccgccc acgcaggcaa cggcaacgtc gggctgtctg ccgatggctt
     6121 ccaacatttg ttctttggct tcattgccga tcacgcattg aaagtcgcgc accatttcgg
     6181 gatacggcgc gggaccggcg gcggtaccga tgatgtagaa tgtgtcatcc acgcgggcga
     6241 cccattcgcg catggcttcg ttcatcgcgt ctttcaaagt acggctgccg ctgtcaacgc
     6301 cgacgacatt cgcgcccaat aatttcatac ggaacacgtt gggcatttgg cgttggatgt
     6361 cgtccgcacc catgtacacg tcgcaagtca tgccgaagcg ggcggcaaca gtggcactcg
     6421 ccacgccgtg ctgacccgcg ccggtttcgg cgatgacgcg ttttttaccc atacgttttg
     6481 ccaacagtgc ctgaccgatg gtgttgttga ctttgtgcgc gccggtgtgg ttcaagtctt
     6541 cgcgcttcaa ccagatttgc gcaccgccca aatgctcgga caaccgcgcg gcgtggtaaa
     6601 cggggctggg cctgccgaca taatgtttca aatcgcggtg gaattcttcc caaaacgacg
     6661 ggtcgttttt cgctgcctta taggcatccg ccagctcttg caaagcggga atcagggtct
     6721 cggacacgaa cagcccgccg tgttcgccga aaaagccctt ctcgtcgggc gcgtggtagt
     6781 tcttcatcgg attcttcctt gtgcttcagg ttttcaaacg gcatttccgt tttttcaaac
     6841 atgccgtccg aacgggaaat tgtcggcaat tataactgct tttcacacaa gcccgccatt
     6901 tcgaaaaacg cccgatacac cgccgccttt ttcgccaaac tcaaaggata ggcgcgcgaa
     6961 gtcgaaggca ggcgcgtcag cgtcaaatcc cgtccggcaa acggaaacgg cacggtttcg
     7021 cccgttttcg gcattttgat gccgccaccc tgaatatcga gcaggatttc cgtcgccttg
     7081 ccgcctgtcg tacaaatatg gcggcactcg ggtatttttg ccaacaccgc cgccaaatcg
     7141 acggtttcaa ctacctttaa aaacttgtcg gacgcattgc cgtgttccct tgccgccttc
     7201 aacacggtcg gacaggacgc aatcccccgt tcgtgcaaaa acgccttgat tttctcggca
     7261 tcaaacgctt tttcagacaa cctttggaaa tgcgccgcat cattaaaaaa caccagcccg
     7321 taaacgcgcc acatatcgtt ttggaaattc ggataatgaa actgcatcgc gcgtttgtct
     7381 tccttgggcg gaaacgtccc catcatcatg accgcagcct tcggcggcaa cacggaatcg
     7441 aagggatggg tttcgatttc aagcagattt tcagacacgt tcaatcctcc aacaggcaaa
     7501 acggcagaca gccggttttt gcaccaaacc gccaaacacg gcaagccttc aaacagcatt
     7561 atcacgccct gccgttttcg gttacaatgc cgacatcaaa cggatactgt aaacacattt
     7621 atgttccaac acacaggacg acacttaaag caccgcccta tgtgccatcc tgatttggaa
     7681 ggagttacgc ccctcccaaa tagagtctga ttctaccgcc ctaaagggcg gggtttcaac
     7741 cgaaaaggaa acacgatgaa agaacacaaa gcccgcaagc gtttcgggca gaattttttg
     7801 caggacacgc ggatcatcag cgatattgtc aacgccgtgc gcccgcaggc ggatgatgtc
     7861 gtgattgaaa tcggcccggg tttggcggcg attaccgaac ctttggcgaa aaagctgaac
     7921 cgcctgcacg ttgtcgaaat cgaccgcgac atcgtatgcc gtctgaaaac gctgccgttt
     7981 gcggataaac tggtgattca cgaaggcgat gtattgcagt ttgatttcaa cggcatcgca
     8041 ggcaaaaaga aaatcgtcgg caacctgccc tacaacattt ccacgccgct tttgttcaag
     8101 ctggcggagg tggcggacga tgtcgtcgat atgcacttta tgctgcaaaa agaagtggtc
     8161 gatcgtatgg ttgccgcgcc gaaaagcaac gactacggcc gcttgggcgt gatgctgcaa
     8221 tatttcttcg atatggaaat gctgattgac gtgccgcccg aatcgttcga ccccgcgccg
     8281 aaagtggatt cggccgtcgt ccgcatgatt ccggtgaaac accgtatcgg caaggcggac
     8341 gatttcgagc atttcgccaa actcgtgaaa ctcgccttcc accaacgccg caaaaccata
     8401 cgcaacaatc tgaaagagct tgcaggcgac gatgatttgc aggcagtcgg catcaatccg
     8461 caagaccgcg ccgaacatat cgcgccggag aaatatgtgg cgttgagcaa ttatctggcg
     8521 ggcaaggccg tctgaaaagg gagtaagccg atgacgaaat acctgctttt acccctgata
     8581 ctgccgcttg cagcctgcct gaccaatccg aacgaccgtt tttttgacgg cagacgctac
     8641 acgcttcatc atatggagct cccgtaacga caacctgcaa cggcaaatgc cgtctgaaag
     8701 aaaagacatg atcaaattca aaaacgtaca caaacatttc aaagacctgc acgtcatcaa
     8761 cggcgtgaac ttggaaatca aaaaaggcga agtggtcgtc gtctgcggac cttcgggcag
     8821 cggcaaatcc acactcatcc gcaccgtcaa ccagcttgaa agcatcgaaa gcggcgagat
     8881 ttgggtggac ggtgtcaacg ttgccgaccc aaaaaccgat ttgaacaaaa tccgcgaaga
     8941 agtcggcttt gtgtttcaaa gtttcaacct ctacccccac ctgaccgtat tggaaaacat
     9001 caccctcgca ccgatgaagg ttaaaggtca aaatgcggaa caggcggaga aaaaagcgat
     9061 ggaacttttg gaacgcgtcg gactggcgca caaaaaagac gcttttccgt cccaactttc
     9121 cggcggccag cagcagcgcg tggcgattgc acgcggtttg gcgatggaac cgcgcgtaat
     9181 gttgtttgac gaaccgacct ccgcactcga ccccgaaatg gtcggcgaag tgttgaaagt
     9241 gatgaaagac ttggcagaaa gcggcatgac catgatgtgc gtaacccacg aaatggggtt
     9301 tgcccgcgaa gttgccgacc gcgtgatttt cgtcgataaa gggcaaatcc tcgaagacga
     9361 aacgcccgaa gcgtttttca ccaacccgaa acacgaacgc gccaagcagt tcctgcaaca
     9421 ggtcatgacc cactgatgct ataccgtctg aaaaccgaac gttcagacgg catagcccga
     9481 caccgcaaga tgattgagaa agaaaaccat gtattttgtt gaccgcaccg ccgtcgtcct
     9541 caagccgacc gtccgctttt tggaatggct caaaagcacc gacgaaaata tgcccgacct
     9601 gaccatagag cagcttcgtg ccaactgctc cgtcttcctc gttccgcagt tcgacgaacc
     9661 ggaagccgtc gtttcctatt tcgacgaacg ctaccgccag atttttgaag ccgaactcgc
     9721 cggctgggac atcgacaagg ataaatggcc gcaagatatg gggctgaagg cgttttggga
     9781 atttttcgac atcgaaatcc acgatatggt gttggatatg gaagaagcgg atttgaacat
     9841 cacgcccgtg ttcgacaata tgatgtaacg ccgtgcgcgc ctttcagaca gcattgaggc
     9901 cgtcccgcat cctgaacatc ctgaccgtat cgctccactc ggcttccctt gccgtctgcc
     9961 tgacctggtt ttacggccgg atgatgtggt tcggtttggc ggctttggcg gcaagttacg
    10021 catactcgct caggataacg aatctgaaac accgccatgc cataaccgcc attaccatag
    10081 accgcgacgg acaggcggaa atcgtatccg gcaaagaaaa aacagcaaag gcggcaacac
    10141 ttgcgggcag cagtatggtt acgccttatg ccttattctt acaatgggac accggcggca
    10201 aaaccgtccg ccactgcatc atgcccgaca tgacggacaa agaatcctac cgcaagctga
    10261 aagtctgggt actttggcgg cagccgaaaa aaaccgccga aaccgataca tcagactgat
    10321 ttcagacggc atttgaaaac gaaacactca tgaaaacact acaagactgg ctctcgcatt
    10381 tggaaaccgc ccacagcggc ggtttgatcg acatgggttt ggagcgcacg agcgaagtga
    10441 aaaaacgcat gaagctcgag ccgcaatgcc ccgtcgtcgt tgtcgcggga accaacggca
    10501 aaggttcggt ctgtgcctac ctgacacaga tttacaaaca ggcgggctac aaaaccggta
    10561 cgctgaccag cccgcattta ttgcgttaca acgaacgcat cgccatcaac gccgaacccg
    10621 tttcggacga tacgattatt gcctctttcg agcgcatcga agcggcgcgc agcgaaatat
    10681 cgctgactta ttttgaattc aatacgttgg cggccgtcga catcttcatg cgcgaacagg
    10741 ttgacgtgat gatattggaa gtcggcttgg gcggacgctt ggacgcggtc aacgcatttg
    10801 acggcgattg cgcggtggtt actagtgtag atttggacca tcaggcgttt ttgggcgata
    10861 cggtcgagca ggtcggcttt gaaaaagcag gcgtgttccg cagcggcaaa cccgcaatct
    10921 gcggtcaaaa ccccgcgccc gaatcgttgc tttcacacgc cgaagccata ggcgcgaaac
    10981 tgctgatggt gcagcgcgat ttcgagtttc acgcgatgga aaacatccaa tggaactacc
    11041 gcttccggcc gcaacattca gacgaccccg cgcgcaaccg caatgccctg cccttccccg
    11101 cattgcgcgg cacataccaa ctttccaacg ccgcctgcac gttgaccgta ttggaatgct
    11161 tgaacgccaa attgccggtg gacatcggcg ccatcaaacg cggattgctg ctggttgaaa
    11221 atcccggacg cttccaagtc ctgcccggcc gtccgctgac cgttttggat gtcggacaca
    11281 atccccacgc tgcccgcgcc ctgcgccgca gcctgattaa tttggcgttt gcgcaaaaac
    11341 gcaccgccgt gttcagcatg ttgtccgaca aagacataga cggcgtgttg gaaaccgtta
    11401 aagaccagtt tgacgagtgg tatatcgcac cgttggatgt accgcgcggc atgacgctcg
    11461 agagcctgca aaacaaactg cacgaacaca gcatcgaaaa catacaaaca ttcgccgccg
    11521 tccgcgaagc ataccgggcg gcagcctcaa aagcgggcga gaacgacaga atcgtcgttt
    11581 tcggctcatt tcataccgtt gccgatgtca tgtcggtact ttaaaaggaa acttctatgt
    11641 ccgaaaacaa acaaaacgaa gtcctgagcg gttacgaaca actcaaacgg cgcaaccgcc
    11701 gccgcctcgt aacggcaagt tgcctggttg ccgcctcctg catcctgctg gcagccgccc
    11761 tcagttccgg ccctgccgaa cagactgccg gcgaaacaag cggcgtagaa aacaaagcgg
    11821 caggtgcggc acaaacccct gccttgaaat ccgccgccga caaaccgcag gacttggcag
    11881 gcgaagacaa gccttctgcc gccgacagcg aaatcagcga gcctgaaaac gtaggcgcgc
    11941 cgctggtgct gattaacgac cgcctcgaag acagcaacat caaaggtttg gaagcatccg
    12001 agaaactgca acaggcagaa accgccaaaa ccgcaccgaa gcaggcaaaa caacgcgctg
    12061 ccgaaaaagt gccggcaact gccgacagta cggatacggt agcggttgaa aaaccgaaac
    12121 gcactgccga aacaaaaccg caaaaagcgg aacgcactgc caaagccaag cccaaagcca
    12181 aagaaaccaa aaccgccgaa aaagttgccg acaaaccgaa aactgccgcc gaaaaaacca
    12241 aaccggatac ggcaaaatcc gacagcgcgg taaaagaagc gaaaaaagcc gacaaggctg
    12301 aaagcagaaa aacagccgaa aaagaccgtt cggacggcaa aaaacacgaa acggcacaaa
    12361 aaaccgacaa agcggacaag accaaaaccg ccgagaagga aaaatccggt aaaaaagccg
    12421 ccattcaggc aggttatgcc gaaaaagaac gcgccttaag cctccagcgc aaaatgaagg
    12481 cggtgggtat cgattcgacc atcaccgaaa ttatgaccga caacggcaaa gtttaccgcg
    12541 tcaaatcaag caactataaa aacgcaaggg atgccgaacg cgatttgaac aaattgcgtg
    12601 tacacggtat cgccggtcag gtaacgaatg aataacctcc ccgttgccga cctcctcgtc
    12661 ttcgccatca tcgccgcctg catcgtgcta tccgcgatgc gcggcgtgat tgcggaggca
    12721 ggttcgatgg cggcatgggt ggtttccttc ttttttgcca aactctttgc cgcacccttc
    12781 gccgacctcg cctttgcctc gttccaaccc cgcctgtttg cattggctct gtcgttcatt
    12841 tccctgttcg tcattgcctg tctgatccag aaaatgctcc gttcgctgct gaccggcgca
    12901 gtttcggcgg tcggtttggg ctttgccaac cgcattttgg gcggcgtatt cggtgcattg
    12961 aaaggcgttt tgattgttac cctgctggtc atgcttgctt caaaaaccga cctgcccgat
    13021 accgaagagt ggctgcagtc ctataccata ccgtttttcg tatcgctttc cgaagccgtg
    13081 ttgaaccata gcggcggcac ggcggaaact ccggaagacg attgattgcc atacggatat
    13141 ttcagacggc attctctttt atgccgtctg aaatgttttt tccttttctc agccatatca
    13201 cagattaaat cttatcctcc ataaacccac ctatctgtcc ttcgctcaaa tattgtcaac
    13261 aattcaggca aaaaaccacc gtttgcttta taattccgtt ttacccttaa acctcgaatc
    13321 ggagaagacg atatgtgcgg cgtattaggt ttggtcagtc atgaacccgt gaaccagctt
    13381 ctgtacgacg gtttgcagat gttgcagcac agggggcagg atgcggcggg cattgcaacg
    13441 gcggaaggcg gcaccttcca tatgcacaaa ggcaaaggga tggtgcgcga agtgttccgc
    13501 acgcgcaata tgcgcgattt ggtcggcaac gccggcatcg cccacgtccg ttatcctacg
    13561 gcgggcaacg ccggcagcag cgcggaggcg cagcctttct acgtcagctc gcctttcggc
    13621 atcgttttgg cgcataacgg caatctcacc aacacggccg aactgtatga aaacgtgtgc
    13681 aacaaacacc tgcgccacgt caacaccagc tccgattccg aagtcttgct caacgtattc
    13741 gcgcacgaat tacgccgcga agtctccaaa aacgccgatc cgcaccggct caatgccgac
    13801 aatattttca acgccgttgc cgaagtccac cgcctagtgc gcggcgcata cggcgtggtt
    13861 gccatgattg cgggctacgg tatgcttgcc ttccgcgacc cttacggcat ccgcccgctg
    13921 gtattgggtt cgcaaaccga caacgaaggc aggaaatcct atgccgtcgc ctccgaatcc
    13981 gtcgccttca acgcgcttgc ctacgatttg gaacgcgaca tccggccggg cgaagcggta
    14041 tttgtcggct ttgacggcac aatgattgcc cgccaatgca gcgaccgtgc caaactcagc
    14101 ccctgccttt ttgaatatgt ttattttgcc cgccccgact ccgtaatcga cggcgtatcg
    14161 gtttaccaat cgcgcttgga tatgggcgtg tccttggcgg aaaaaatcaa acgcgagctg
    14221 cccgtggacg acatcgatgt cgtgatgccc attcccgaca ccagccgccc cagcgcgatg
    14281 gagcttgccg tccacctcga caaaccctac cgcgagggct tgattaaaaa ccgctatatc
    14341 ggccgcacct ttattatgcc cggccaggcg acgcgcaaaa aatccgtgcg ccaaaaactc
    14401 agcccgatgg aaaccgagtt tgcaggcaaa agcgtgttgc tggtggacga ctccatcgtg
    14461 cgcgggacga ccagccgcga aatcgtcgaa atggtacgcg cggcgggcgc gcgcaaagtc
    14521 tatatcgcct ccgccgcccc cgaagtgcgc tatcccaacg tatacggcat cgatatgccc
    14581 acgcgcgaag agttgattgc caacgggcgc agcgcggcgg aaatcgccgc cgaaatcggc
    14641 gcggacggca tcgtgttcca aaatttgagc gatttggaag ccgtcgtcaa agcactcaat
    14701 ccgaaaatcg aatccttcga ttcgtcctgt ttcaacggca tttatcagac cggcgacatc
    14761 gatgatgcct acctcgaccg cctgtctgcc gagaaatccg gctgcggcgg cctgaaaatc
    14821 cacccgagta ggatggaaca cagcatcagc atcagcgatg cgggcgacga agaataaggc
    14881 ttcccaaacc gcgatgccgt ctgaaatccg aacgccgggt tttcagacgg catttcccat
    14941 atcggcatca catttcccat ttcatccgca cgcaatatga gtaccgaaac caaaaactac
    15001 attacgcccg ccggatggca ggcattgaaa gacgagcttt atcaactggt taataaagaa
    15061 cgccccgaaa tcgtccaaat cgtcaactgg gcggcaggca acggcgaccg cagcgaaaac
    15121 ggcgactatc tttacggcaa acgccgtatg cgcgaaatcg accgccgcat ccgtttcctg
    15181 accaagcgtt tggagtccgc cgtcgtcgtc gatcccgaat tgcgcgaagc gaccgaccaa
    15241 gtatttttcg gcgcgacggt cgggctgttg cgcggcgacg ggcgcgagca aaccgtcaaa
    15301 attgtcggca tcgatgaaat cgataccgcg caaaacaaaa tttcttggat ttcgccgttg
    15361 gcgcgttgcc tgattaaagc gcgcgaaggc gacgaagtgg ttttgaacac gccggaaggg
    15421 cgtgaggaaa ttgaaatcct ttctgtcgaa tacatcaaaa tcgactgatc gggaatgccg
    15481 tctgaaacgg cacaaacgca tcgtttccca aataaaggaa taccgaatga ggaaaatccg
    15541 caccaaaatc tgcggcatca ccacactgga agacgcagcg gccgccgcag cggcaggtgc
    15601 ggatgccgtc gggctggtct ttttccaagg cagcagccgg gccgtcgata ttgcccgcgc
    15661 caaaaaaatc accgccgcac tgccgccgtt tgtcagcgtt gtcgcccttt tcgtcaacga
    15721 aagcgcgcaa aacatccgcc gcatccttgc cgaagtgccg atacacatca tccaattcca
    15781 cggcgacgaa gacgacgcat tctgccgcca gttcgaccgc ccctatatca aggccattcg
    15841 tgttcagacg gcatcagaca tccgaaacgc cgccgaccgc ttccccgacg ctcaggcact
    15901 gctgttcgat gcctaccacc cttcggaata cggcggcacc ggacaccgct tcgactggac
    15961 gctgctggcg gaatattcgg gcaaaccgtg ggtgcttgcc ggcgggctga cccctgaaaa
    16021 cgtcggcgaa gccgtccgca tcaccggagc ggaagcggtc gatgtatccg gcggcgtgga
    16081 agcgtctaaa ggcaaaaaag acccagccaa agttgccgcc tttatcgcaa ccgccaaccg
    16141 cctatcccgt taaagcaaca aaaattgccg ccggaatga
//
LOCUS       DAXISH010000049        16145 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.049, whole genome shotgun sequence.
ACCESSION   DAXISH010000049 DAXISH010000000
VERSION     DAXISH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 16145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16145
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.049"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            6..81
                     /locus_tag="ACFOV4_001543"
     tRNA            6..81
                     /locus_tag="ACFOV4_001543"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Trp,seq:cca)
     gene            196..474
                     /gene="secE"
                     /locus_tag="ACFOV4_001544"
     CDS             196..474
                     /gene="secE"
                     /locus_tag="ACFOV4_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFC7619522.1"
                     /translation="MTEHTPEKKNVKVDQLVVQDKESASNSGKEGFFAYFSNSWSEFK
                     KVVWPKREDAVRMTVFVIVFVAVLSIFIYAADTAISWLFFDVLLRREG"
     gene            476..1012
                     /gene="nusG"
                     /locus_tag="ACFOV4_001545"
     CDS             476..1012
                     /gene="nusG"
                     /locus_tag="ACFOV4_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFC7619523.1"
                     /translation="MSKKWYVVQAYSGFEKNVQRILEERIAREEMGDYFGQILVPVEK
                     VVDIRNGRKTISERKSYPGYVLVEMEMTDDSWHLVKSTPRVSGFIGGRANRPTPISQR
                     EAEIILQQVQTGIEKPKPKVEFEVGQQVRVNEGPFADFNGVVEEVNYERNKLRVSVQI
                     FGRETPVELEFSQVEKIN"
     gene            1113..1547
                     /gene="rplK"
                     /locus_tag="ACFOV4_001546"
     CDS             1113..1547
                     /gene="rplK"
                     /locus_tag="ACFOV4_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFC7619524.1"
                     /translation="MAKKIIGYIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNA
                     ATQGMEPGLPIPVVITAFADKSFTFVMKTPPASILLKKAAGLQKGSSNPLTNKVGKLT
                     RAQLEEIAKTKDPDLTAADLDAAVRTIAGSARSMGLDVEGVV"
     gene            1547..2242
                     /gene="rplA"
                     /locus_tag="ACFOV4_001547"
     CDS             1547..2242
                     /gene="rplA"
                     /locus_tag="ACFOV4_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFC7619525.1"
                     /translation="MAKVSKRLKALRSSVEANKLYAIDEAIALVKKAATAKFDESVDV
                     SFNLGVDPRKSDQVIRGSVVLPKGTGKTTRVAVFTQGANAEAAKEAGADIVGFEDLAA
                     EIKAGNLNFDVVIASPDAMRIVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VQYRTDKAGIVHATIGRASFAEADLKENFDALLDAIVKAKPAAAKGQYLKKVAVSSTM
                     GLGIRVDTSSVNN"
     gene            2472..2972
                     /gene="rplJ"
                     /locus_tag="ACFOV4_001548"
     CDS             2472..2972
                     /gene="rplJ"
                     /locus_tag="ACFOV4_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFC7619526.1"
                     /translation="MSLNIETKKVAVEEISAAIANAQTLVVAEYRGISVSSMTELRAN
                     ARKEGVYLRVLKNTLARRAVQGTSFAELADQMVGPLVYAASEDAVAAAKVLHQFAKKD
                     DKIVVKAGSYNGEVMNAAQVAELASIPSREELLSKLLFVMQAPVSGFARGLAALAEKK
                     AGEEAA"
     gene            3030..3401
                     /gene="rplL"
                     /locus_tag="ACFOV4_001549"
     CDS             3030..3401
                     /gene="rplL"
                     /locus_tag="ACFOV4_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFC7619527.1"
                     /translation="MAITKEDILEAVGSLTVMELNDLVKAFEEKFGVSAAAVAVAGPA
                     GAGAADAEEKTEFDVVLASAGDQKVGVIKVVRAITGLGLKEAKDIVDGAPKTIKEGVS
                     KAEAEDIQKQLEEAGAKVEIK"
     gene            3593..7771
                     /gene="rpoB"
                     /locus_tag="ACFOV4_001550"
     CDS             3593..7771
                     /gene="rpoB"
                     /locus_tag="ACFOV4_001550"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFC7619528.1"
                     /translation="MSYSFTEKKRIRKSFAKRENVLEVPFLLATQIDSYAKFLQLENA
                     FDKRTDDGLQAAFNSIFPIVSHNGYARLEFVHYTLGEPLFDIPECQLRGITYAAPLRA
                     RIRLVILDKEASKPTVKEVRENEVYMGEIPLMTPSGSFVINGTERVIVSQLHRSPGVF
                     FEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDLLYFRIDRRRKMPVTILLKALG
                     YNNEQILDIFYDKETFYLSSNGVQTDLVADRLKGETAKVDILDKEGNVLVAKGKRITA
                     KNIRDITNAGLTRLDVEPESLLGKALAADLIDSETGEVLASANDEITEELLAKFDING
                     VKEITTLYINELDQGAYISNTLRTDETAGRQAARVAIYRMMRPGEPPTEEAVEQLFNR
                     LFFSEDSYDLSRVGRMKFNTRTYEQKLSEAQQNSWYGRLLNETFAGAADKGGYVLSVE
                     DIVASIATLVELRNGHGEVDDIDHLGNRRVRSVGELTENQFRSGLARVERAVKERLNQ
                     AESENLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLT
                     RERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYARTNDYGFLETPYRRVIDG
                     KVTEEIDYLSAIEEGRYVIAQANADLDKDGNLIGDLVTCREKGETIMATPDRVQYMDV
                     ATGQVVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPMVGTGIERSVAVDSA
                     TAIVARRGGVVEYVDANRVVIRVHDDEATAGEVGVDIYNLVKFTRSNQSTNINQRPAV
                     KAGDVLQRGDLVADGASTDLGELALGQNMTIAFMPWNGYNYEDSILISEKVAADDRYT
                     SIHIEELNVVARDTKLGAEDITRDIPNLSERMQNRLDESGIVYIGAEVEAGDVLVGKV
                     TPKGETQLTPEEKLLRAIFGEKASDVKDTSLRMPTGMSGTVIDVQVFTREGIQRDKRA
                     QSIIDSELKRYRLDLNDQLRIFDNDAFDRIERMIVGQKANGGPMKLAKGSEITTEYLA
                     GLPSRHDWFDIRLTDEDLAKQLELIKVSLQQKREEADELYEIKKKKLTQGDELQPGVQ
                     KMVKVFIAIKRRLQAGDKMAGRHGNKGVVSRILPVEDMPYMADGRPVDIVLNPLGVPS
                     RMNIGQILEVHLGWAAKGIGERIDRMLKEQRKAGELREFLNKLYNGSGKKEDLDALTD
                     EEIIELASNLRKGASFASPVFDGAKESEIREMLNLAYPSDDPEVEKLGFNDSKTQITL
                     YDGRSGEAFDRKVTVGVMHYLKLHHLVDEKMHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYENIVKGEHKIDAGMPESFNVLVK
                     EIRSLGLDIDLERY"
     gene            7928..12103
                     /gene="rpoC"
                     /locus_tag="ACFOV4_001551"
     CDS             7928..12103
                     /gene="rpoC"
                     /locus_tag="ACFOV4_001551"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFC7619529.1"
                     /translation="MNLLNLFNPLQTAGMEEEFDAIKIGIASPETIRSWSYGEVKKPE
                     TINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKFKGVTCEKCGVEVTLSKVRRE
                     RMGHIELAAPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVTDPGMTPLQRRQ
                     LLTEDDYYNKLDEYGDDFDAKMGAEGIRELLRTLNVAGEIEILRQELESTGSDTKIKK
                     IAKRLKVLEAFHRSGMKLEWMIMDVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVIN
                     RNNRLKRLLELHAPDIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIK
                     GKGGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIFHKLEKQGL
                     ASTVKAAKKLVEQEVPEVWDILEEVIREHPIMLNRAPTLHRLGIQAFEPILIEGKAIQ
                     LHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLSPANGEPIIVPSQDI
                     VLGLYYMTRDRINAKGEGSLFADVKEVHRAYHTKQVELGTKITVRLREWVKNEAGEFE
                     PVVNRYETTVGRALLSEILPKGLPFEYVNKALKKKEISKLINASFRLCGLRDTVIFAD
                     HLMYTGFGFAAKGGISIAVDDMEIPKEKAALLAEANAEVKEIEDQYRQGLVTNGERYN
                     KVVDIWGRAGDKIAKAMMDNLSKQKVIDRDGNEVNQESFNSIYMMADSGARGSAAQIK
                     QLSGMRGLMAKPDGSIIETPITSNFREGLTVLQYFIATHGARKGLADTALKTANSGYL
                     TRRLVDVTQDLVVVEDDCGTSDGFVMKAVVQGGDVIEALRDRILGRVTASDVVDPSSG
                     ETLVEAGTLLTEKLVDMIDQSGVDEVKVRTPITCKTRHGLCAHCYGRDLARGKLVNAG
                     EAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQVEAKSNGTARFSSQMRYVANN
                     KGELVVIGRSCEVVIHDDIGRERERHKVPYGAILLVQDGAAIKAGQTLATWDPHTRPM
                     ITEHAGMVKFENVEEGVTVAKQTDDVTGLSTLVVIDGKRRSSSASKLLRPTVKLLDEN
                     GVEICIPGTSTPVSMAFPVGAVITVREGQEIGKGDVLARIPQASSKTRDITGGLPRVA
                     ELFEARVPKDAGMLAEITGTVSFGKETKGKQRLIITDVDGVAYETLISKEKQILVHDG
                     QVVNRGETIVDGAVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKISDKHIEVIIRQ
                     MLRRVNIADAGETGFITGEQVERGDVMAANEKALEEGKEPARYENVLLGITKASLSTD
                     SFISAASFQETTRVLTEAAIMGKQDELRGLKENVIVGRLIPAGTGLTYHRSRHQQWQG
                     VEQETAETQVTDE"
     gene            12395..12652
                     /locus_tag="ACFOV4_001552"
     CDS             12395..12652
                     /locus_tag="ACFOV4_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619530.1"
                     /translation="MKPRNLFFAGCLLTSATFAEDIGVPVELINVGNRIAMPSEGESL
                     ALLPFAEDVPPVRDAMPSEVPKSAAGGDVRGNRMGMPINIG"
     gene            12649..12798
                     /locus_tag="ACFOV4_001553"
     CDS             12649..12798
                     /locus_tag="ACFOV4_001553"
                     /inference="COORDINATES: protein motif:HMM:NF016462.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein assembly modifier"
                     /protein_id="HFC7619531.1"
                     /translation="MSAALWHKKLSWKGFTPQINFRYNKINSNMPAFYSRSGKERFVS
                     IEKTY"
     gene            12977..13348
                     /gene="rpsL"
                     /locus_tag="ACFOV4_001554"
     CDS             12977..13348
                     /gene="rpsL"
                     /locus_tag="ACFOV4_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFC7619532.1"
                     /translation="MPTINQLVRKGRQKPVYVNKVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSL
                     DTAGVKDRKQARSKYGAKRPK"
     gene            13466..13936
                     /gene="rpsG"
                     /locus_tag="ACFOV4_001555"
     CDS             13466..13936
                     /gene="rpsG"
                     /locus_tag="ACFOV4_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008955889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFC7619533.1"
                     /translation="MPRRREVPKRDVLPDPKFGSVELTKFMNVLMIDGKKSVAERIVY
                     GALEQIEKKTGKVAIEVFNEAIANAKPIVEVKSRRVGGANYQVPVEVRPSRRLALAMR
                     WVRDAARKRGEKSMDLRLAGELIDASEGRGGALKKREEVHRMAEANKAFSHFRF"
     gene            13955..16060
                     /gene="fusA"
                     /locus_tag="ACFOV4_001556"
     CDS             13955..16060
                     /gene="fusA"
                     /locus_tag="ACFOV4_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFC7619534.1"
                     /translation="MARKTPISLYRNIGISAHIDAGKTTTTERILFYTGLTHKLGEVH
                     DGAATTDYMEQEQERGITITSAAVTSYWSGMAKQFPEHRFNIIDTPGHVDFTVEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYQVPRLAFVNKMDRQGANFFRVVEQMKT
                     RLRANPVPIVIPVGAEDNFSGVVDLLKMKSIIWNEADKGTTFTYGDIPAELVETAEEW
                     RQNMIEAAAEASEELMDKYLGGDELTEEEIVGALRQRTLAGEIQPMLCGSAFKNKGVQ
                     RMLDAVVELLPAPTDIPPVQGVNPNTEEADSRQASDEEKFSALAFKMLNDKYVGQLTF
                     IRVYSGVVKSGDTVLNSVKGTRERIGRLVQMTAADRTEIEEVRAGDIAAAIGLKDVTT
                     GETLCAESAPIILERMEFPEPVIHIAVEPKTKADQEKMGIALNRLAKEDPSFRVRTDE
                     ESGQTIISGMGELHLEIIVDRMKREFGVEANIGAPQVAYRETIRKAVKAEYKHAKQSG
                     GKGQYGHVVIEMEPMEPGGEGYEFIDEIKGGVIPREFIPSVDKGIRDTLPNGIVAGYP
                     VVDVRIRLVFGSYHDVDSSQLAFELAASQAFKEGMRQASPALLEPIMAVEVETPEEYM
                     GDVMGDLNRRRGVVLGMDDDGIGGKKVRAEVPLAEMFGYSTDLRSATQGRATYSMEFK
                     KYSEAPAHIAAAVTEARKG"
BASE COUNT         4297 a         3583 c         4176 g         4089 t
ORIGIN      
        1 tttagaggcc aatagctcaa ttggtagagt atcggtctcc aaaaccgagg gttgggggtt
       61 cgagaccctc ttggcctgcc aaataaaaaa ttaaccggcc ttgtgtcggt taattttttt
      121 gtatttgtta tttagtaaac tctcttgcca tttacatgga ttgagaatag acagatgcta
      181 tgatggataa ataatatgac agaacatacg cctgaaaaaa agaacgttaa agtggatcaa
      241 ctggttgttc aagataaaga atctgcatct aattccggta aggaagggtt ttttgcatat
      301 ttctcaaatt cttggtccga attcaaaaag gtggtttggc ctaagcgtga agatgctgtc
      361 agaatgactg tatttgttat agtgtttgtt gctgtgcttt ctatatttat ctatgcggca
      421 gatacagcaa tttcgtggtt attttttgat gtattgctga gaagggaagg ttgagatgtc
      481 gaaaaaatgg tatgttgtac aggcgtattc ggggtttgag aagaatgtcc aacgaatatt
      541 ggaagagcgc attgcccgtg aggagatggg agattatttc ggacaaattc tggtgcctgt
      601 agagaaagtt gttgatatcc gcaatggtcg taagactatt agtgaaagaa agtcatatcc
      661 tggttatgtg ctagttgaga tggaaatgac agatgactct tggcatcttg taaaaagcac
      721 cccccgtgtt tccggtttta ttggagggag ggctaataga cctacgccga ttagtcagag
      781 agaggctgaa attattttac agcaggttca gaccggcata gagaagccga aaccaaaagt
      841 tgaatttgag gtcggtcaac aggttcgtgt aaatgaaggg ccgtttgcgg attttaacgg
      901 ggtggttgag gaggtcaatt atgaacggaa taagttacgc gtgtctgttc agatatttgg
      961 tagagaaaca cccgttgagc tggagttcag ccaggttgaa aagattaact gatttttata
     1021 cttgaaaaaa aagcaataag aggatagaat caaaaattaa cttggggagc ggaaatggtt
     1081 ccgcgtctta cccgttttta ggagttcgtt aagtggcaaa gaaaattatc ggctatatta
     1141 aactgcaaat tcctgcaggt aaagccaatc catctcctcc ggttggtcct gctttgggtc
     1201 agcgcggttt gaatattatg gaattttgta aggcatttaa tgctgcaacc caaggtatgg
     1261 agcctggctt accgattccg gttgtgatta ctgcatttgc agataaatca ttcacatttg
     1321 tgatgaaaac cccgccagct tctatcttgt tgaaaaaggc tgccggtttg caaaaaggta
     1381 gttctaatcc tctgaccaac aaagtgggta aattgacccg tgcccagttg gaagaaattg
     1441 ctaaaactaa agatcctgat ttgactgctg ctgacttgga tgcggctgtc cgtactatag
     1501 caggttctgc tcgctcaatg ggcttggatg tggagggtgt tgtataatgg ctaaagtatc
     1561 taaacgcttg aaagctcttc gctcttctgt ggaagccaat aaattatatg caattgatga
     1621 agcaattgct ttggtaaaaa aagcagcgac tgctaaattt gacgagtctg ttgacgtatc
     1681 tttcaacttg ggcgttgatc cgcgtaaatc tgaccaagtt atccgtggtt cggtcgttct
     1741 gcctaaaggc accggtaaga caacccgtgt ggctgtattt actcaaggtg caaatgcaga
     1801 agctgctaaa gaagctggtg cagatatcgt cggtttcgaa gatttggctg ctgaaatcaa
     1861 agcaggcaat ctgaactttg acgttgttat tgcttctccc gatgcaatgc gtattgttgg
     1921 tcaattgggt accatcttgg gccctcgtgg tctgatgcca aaccctaaag taggtacggt
     1981 tacccctaat gttgccgaag cagtaaaaaa tgcaaaagca ggtcaagtgc agtaccgtac
     2041 cgacaaggca ggtattgttc atgcaacgat tggtcgtgct tcattcgctg aagctgattt
     2101 gaaagagaac tttgatgcgt tgctggatgc tatcgttaaa gccaagcctg ctgccgctaa
     2161 aggtcagtat ctgaaaaaag ttgctgtgtc tagcaccatg ggtttgggta ttcgcgttga
     2221 tacatcaagc gtaaataact aatcttaagg aattttcaag cagtttggtt ttctgggctg
     2281 cttgaatttg ggctacttaa aattaagtag atgtccaaga ccgtagggat cgtaagattt
     2341 aatcgtaact gccctacgca gacggtagtc ctgaaacaca ttgcaagatt gcttgtaaga
     2401 tgtcttttta ggttaccgcg ctggtgggat atcgttttgg tatcctgttt ataaacagtg
     2461 ggaggtagac cttgagtctc aatattgaaa ccaagaaagt ggcggtcgag gaaattagcg
     2521 cggcaattgc taatgctcaa accctcgtag tcgctgaata tcgcggtatc agtgtttcca
     2581 gtatgactga gcttcgtgcg aatgcacgta aagaaggcgt ttatttgcgc gttctgaaaa
     2641 atactttggc tcgtcgtgca gtgcaaggta cttcatttgc agaattggcc gatcaaatgg
     2701 ttggtccgtt ggtttacgct gcttctgaag atgctgttgc tgctgctaaa gtgttgcacc
     2761 aattcgcgaa aaaagatgac aaaattgtcg ttaaagccgg ttcttacaat ggcgaagtaa
     2821 tgaatgctgc tcaggttgct gagttggctt ctattccgag ccgcgaagag ctgttgtcca
     2881 aactgttgtt cgttatgcaa gctcctgtat cgggctttgc gcgcggtttg gctgctttgg
     2941 cagagaaaaa agccggcgaa gaagccgctt aatcgatttt gtttctgtta atcaattatt
     3001 ttttaataca atatttggag taaaatagca tggctattac taaagaagac attttggaag
     3061 cagttggttc tttgaccgta atggaattga acgacttggt taaagctttt gaagaaaaat
     3121 tcggtgtttc tgctgctgct gttgcagttg caggtcctgc tggtgccggt gctgccgatg
     3181 ctgaagaaaa aaccgaattt gatgtcgttt tggcttctgc cggcgatcaa aaagtcggcg
     3241 tgattaaagt tgtccgtgca attaccggtt tgggtctgaa agaagctaaa gacatcgttg
     3301 acggtgcacc taaaaccatt aaagagggtg tttctaaagc tgaagccgaa gacatccaaa
     3361 aacaactgga agaagccggc gctaaagtcg aaatcaaata atttgatgct tcttatgaag
     3421 gctggcagtt ttctgccagc cttattttgc ttcttaaaat aagcatcaat ctgatgttta
     3481 catttatttg catagttttt atcaaatcat tgcaaataaa tgtaaacatc agattgatgc
     3541 gtgccgttgc tttcagacgg cctattattg aaaattactt ttcggagtgt atatgagcta
     3601 ttcgtttacc gagaaaaaac gtatccgtaa gagttttgca aagcgggaaa atgttttgga
     3661 agttcctttc ctgctggcaa cccaaattga ttcttatgcg aagtttttgc agctggaaaa
     3721 tgcttttgac aaacgtaccg atgacggtct gcaggcggca tttaattcta ttttcccgat
     3781 tgtgagccat aacggttatg cgcgattgga gtttgtgcat tacacattgg gcgagccttt
     3841 gttcgatatt cccgaatgtc agttgcgcgg aatcacttat gcagccccct tgcgcgcgcg
     3901 tatccgtttg gtgattttgg ataaggaagc atctaaaccg acggtaaaag aagttcgtga
     3961 aaacgaagtg tatatgggcg aaattccgtt gatgaccccg agcggttctt ttgtgattaa
     4021 cggcacagag cgtgtgattg tctcccagtt gcaccgttcg cccggtgtat tcttcgagca
     4081 tgacaaaggt aagacgcact cttccggcaa attgttattc tccgcccgca tcattcccta
     4141 ccgtggttca tggttggatt ttgaatttga tccgaaagat ttgctgtatt tccgtatcga
     4201 ccgccgccgt aaaatgccgg taacgatttt gttgaaggct ttgggctaca acaatgagca
     4261 aatcttggat attttctacg acaaagaaac gttctatttg tcttcaaacg gtgttcaaac
     4321 cgatttggtc gcagaccgtc tgaaaggcga aactgccaag gtcgatatct tggataaaga
     4381 aggcaatgta ttggttgcca aaggtaagcg cattactgcg aaaaatatcc gtgatattac
     4441 caatgcaggc ctgacccgtt tggatgtaga accggaaagc ctgctgggca aagcattggc
     4501 tgccgatctg attgattcgg aaaccggcga ggtattggct tctgccaatg atgaaattac
     4561 agaagagttg ttggccaaat ttgatatcaa cggcgtaaaa gaaattacga ccctttatat
     4621 caatgagctg gatcagggtg cttatatctc caataccttg cgtacggatg agactgccgg
     4681 ccggcaggcg gctcgtgttg cgatttaccg tatgatgcgt ccgggcgaac cgcccaccga
     4741 agaggcggtc gagcaattgt ttaaccgctt gttcttcagt gaagacagct acgatctgtc
     4801 ccgcgtaggc cgtatgaaat ttaatacgcg cacatacgaa caaaaactgt ccgaagccca
     4861 acaaaactct tggtacggcc gcctgctgaa cgaaacgttt gccggtgctg ccgacaaagg
     4921 cggttatgtc ctgagcgtcg aagatattgt cgcctcgatt gcgactttgg tcgagttgcg
     4981 taacggccat ggcgaagtgg acgatatcga tcacttgggc aaccgccgag tacgttcggt
     5041 aggcgagctg actgaaaacc aattccgtag cggtttggcc cgtgtggaac gtgccgtaaa
     5101 agaacgtttg aatcaggcgg aatcagaaaa cttgatgccg cacgatttga ttaatgcaaa
     5161 acctgtttct gccgctatta aagaattctt cggctccagc caattgagtc agtttatgga
     5221 tcagaccaac cccttgtctg aagtaaccca taaacgccgt gtatctgcat tgggtccggg
     5281 cggtttgacc cgcgaacgtg caggatttga ggtgcgggac gtgcatccga cccactacgg
     5341 tcgcgtatgt ccgattgaaa cgcctgaagg tccgaacatc ggtttgatca actcattgtc
     5401 cgtttatgcg cgcaccaatg attacggttt cttggaaacg ccttaccgcc gcgttatcga
     5461 cggcaaagta actgaagaaa tcgactactt gtctgccatc gaagaaggcc gctatgtgat
     5521 tgcacaggcg aatgccgatt tggacaaaga cggcaatctg attggcgact tggttacttg
     5581 tcgtgaaaaa ggcgaaacca ttatggcaac gcctgaccgc gttcaatata tggacgtggc
     5641 aaccggtcaa gtggtatccg ttgcagcatc cctgattccg ttcttggaac acgatgacgc
     5701 gaaccgcgca ttgatgggtg cgaatatgca acgtcaggca gtgccttgct tgcgtcctga
     5761 aaaaccgatg gtcggtaccg gtatcgagcg ttccgttgcc gttgactctg ctactgcaat
     5821 cgttgcccgc cgaggcggcg tggtcgagta tgtcgatgcc aaccgtgttg tgattcgtgt
     5881 ccatgacgac gaagcgactg ccggcgaagt gggtgtcgat atttacaact tggttaaatt
     5941 tacccgttcc aaccagtcta ccaatatcaa tcagcgtcct gccgtcaaag ccggcgatgt
     6001 tttgcaacgc ggcgatttgg tggccgatgg cgcgtccacc gatttgggcg aattggcttt
     6061 gggtcaaaat atgaccatcg ccttcatgcc gtggaacggt tacaactacg aagactcgat
     6121 tctgatttcc gaaaaagtgg ctgcggacga ccgctatact tcgattcaca ttgaggaatt
     6181 gaatgtcgtt gcccgcgata ccaagctggg tgcggaagac attacccgcg atattccgaa
     6241 cttgtccgag cgtatgcaaa accgtttgga cgaatccggt atcgtttaca tcggtgcgga
     6301 agtagaagcc ggcgatgtgt tggtaggcaa ggtaacgcct aaaggcgaaa cccagctgac
     6361 gccggaagaa aaactgctgc gcgccatctt cggtgaaaaa gcatctgacg taaaagatac
     6421 ttcattgcgt atgcctaccg gcatgagcgg taccgttatc gacgttcaag tcttcactcg
     6481 tgaaggtatt caacgcgaca aacgtgctca atccattatc gattccgagt tgaaacgcta
     6541 ccgtttggat ttgaacgacc aattgcgtat tttcgacaac gacgcattcg accgtatcga
     6601 gcgtatgatt gtcggtcaga aagccaacgg cggcccgatg aagctggcca aaggcagtga
     6661 aatcacgacc gaatatctgg cgggtctgcc gagcaggcac gattggttcg atatccgtct
     6721 gaccgatgaa gatttggcca agcagttgga actgattaaa gtgagcctgc aacaaaaacg
     6781 cgaagaagcg gacgagttat acgaaatcaa gaagaaaaaa ctgacccaag gcgacgaatt
     6841 gcaacccggc gtacaaaaaa tggtgaaagt ttttatcgcc atcaaacgcc gtctgcaagc
     6901 cggcgacaaa atggcgggcc gccacggtaa caaaggcgtg gtatcgcgca ttctgccagt
     6961 ggaagacatg ccttacatgg cggacggccg tccggtagac atcgtactga acccattggg
     7021 cgtaccttcc cgtatgaaca tcggtcagat tttggaagtt cacttgggtt gggcagcaaa
     7081 aggtatcggc gagcgtatcg accgtatgct gaaagagcaa cgcaaagcag gcgagttgcg
     7141 cgagttcttg aacaaactct acaacggcag cggcaagaaa gaagatttgg atgccctgac
     7201 tgatgaagaa atcatcgaac tggcctccaa cctgcgcaaa ggtgcatctt tcgcctctcc
     7261 tgtattcgac ggtgcgaaag agtctgaaat ccgcgaaatg ttgaacttgg cttatccgag
     7321 cgacgatcct gaggttgaaa aactgggctt caacgacagt aaaacccaaa tcacgctgta
     7381 tgacggccgt tcaggcgaag catttgaccg caaggttaca gtaggtgtga tgcactatct
     7441 gaaactgcac cacttggttg acgaaaaaat gcacgcgcgt tctaccggtc cgtacagtct
     7501 ggttacccag cagcctttgg gcggtaaagc ccagttcggc ggccaacgtt tcggtgagat
     7561 ggaggtttgg gcactggaag catacggcgc agcctacacg ctgcaagaga tgctgactgt
     7621 gaagtctgac gacgtgaacg gccgtaccaa aatgtacgaa aacatcgtca aaggcgaaca
     7681 caaaatcgat gccggtatgc ccgagtcctt caacgtattg gtcaaagaga ttcgctcact
     7741 gggcttggat atcgatttgg aacgttacta aacaaaagtt ttcagacggc ctttcagggt
     7801 cgtctgaaaa agtggtttca gaataagaat gaagcaatcg gcatttaggc cgtctgaaat
     7861 caaaagtacc gtttccccat atcgaaaatc cgccatgcgg taaaaatact tccttcaagg
     7921 agcaaaaatg aatttgttga acttatttaa tccgttgcaa actgccggca tggaagaaga
     7981 gtttgatgcc attaaaatcg gtattgcctc tcccgaaacc atccgctcat ggtcttatgg
     8041 cgaagttaaa aaacctgaaa ccatcaacta ccgtacgttc aaacctgagc gtgacggttt
     8101 gttctgtgcc aaaatctttg gcccggtcaa agactacgaa tgcttgtgcg gaaaatacaa
     8161 acgcttgaaa tttaaaggtg taacttgtga aaaatgcggc gtggaagtaa ccctgtccaa
     8221 agtgcgccgc gaacgcatgg gccatatcga attggctgcg cccgtcgcac atatttggtt
     8281 cttaaaatcc ctgccttccc gcttgggtat ggtgttagac atgactttgc gcgatatcga
     8341 acgcgtattg tactttgaag catttgtggt aaccgatccc ggtatgactc cgctgcaacg
     8401 ccgccaattg ctgactgaag acgattacta caacaagctg gacgaatacg gcgacgactt
     8461 cgatgccaaa atgggtgcag aaggtatccg cgaattgctg cgtaccttga atgtagcagg
     8521 cgaaatcgaa atcctgcgcc aagagttgga atcgaccggt tccgacacca aaatcaaaaa
     8581 aatcgccaaa cgcttgaaag tattggaagc tttccatcgt tccggtatga agctggaatg
     8641 gatgattatg gatgtgctgc cggtattgcc gcctgatttg cgtccgttgg ttccattgga
     8701 tggcggtcgt tttgccactt ccgatttgaa cgatttgtac cgtcgcgtca tcaaccgtaa
     8761 caaccgtctg aaacgtctgt tggaactgca tgcgcccgac attatcgtcc gcaacgaaaa
     8821 acgtatgttg caagaagcag ttgactcgct gttggataac ggccgtcgcg gtaaagccat
     8881 gaccggcgcc aacaaacgcc cgctgaaatc attggcagac atgattaaag gtaaaggcgg
     8941 tcgcttccgt caaaacctgt tgggcaaacg tgtggactac tccggccgtt ccgtgattac
     9001 cgtaggccca tacctgcgtc tgcaccaatg cggtctgccg aaaaaaatgg ctttggaatt
     9061 gttcaaaccg ttcattttcc acaaattgga aaaacaaggt ttggcttcta ctgttaaagc
     9121 tgcgaaaaaa ttggtagaac aagaagtacc tgaagtatgg gatatcttgg aagaagtcat
     9181 ccgcgaacat ccgattatgt tgaaccgtgc gccaaccctg caccgtttgg gtattcaagc
     9241 gttcgaaccc atcctgattg aaggtaaagc cattcagttg catccgttgg tatgtgccgc
     9301 atttaacgcc gactttgacg gcgaccaaat ggcggtacac gttccattga gcttggaagc
     9361 acaaatggaa gcacgcacgc tgatgctggc ttcaaacaac gtattgtctc ctgccaacgg
     9421 cgaaccgatt atcgtacctt cccaagacat cgtattgggt ctgtactaca tgacccgcga
     9481 ccgtatcaat gccaaaggcg agggcagcct gtttgccgat gtgaaagaag tgcatcgcgc
     9541 ataccatacc aaacaggtcg agctgggtac gaaaattacc gtacgtctgc gcgaatgggt
     9601 gaaaaacgaa gcaggtgagt ttgagcctgt cgttaaccgt tacgaaacaa ccgtcggccg
     9661 tgcattgttg agcgaaatcc tgccgaaagg cctgccgttt gaatatgtca acaaagcgtt
     9721 gaagaaaaaa gaaatttcta aactgattaa cgcatcgttc cgcctgtgcg gcttgcgcga
     9781 tacggttatc tttgctgacc acctgatgta caccggtttc ggatttgcgg caaaaggcgg
     9841 tatttccatt gccgttgacg atatggaaat tccaaaagaa aaagcggcct tgctggctga
     9901 agccaatgcc gaggttaaag aaatcgaaga ccaataccgt caaggtttgg ttaccaacgg
     9961 cgaacgctac aacaaggtgg tcgatatttg gggtcgtgcc ggcgataaaa tcgctaaagc
    10021 gatgatggac aacctgtcca aacagaaagt tatcgaccgt gacggcaacg aagtcaatca
    10081 agagtcattc aactccatct atatgatggc ggactccggt gcccgtggtt ctgcggctca
    10141 gattaaacag ttgtccggta tgcgcgggtt gatggctaaa cctgacggct cgattattga
    10201 aacgccgatt acctcaaact tccgcgaagg tttgaccgta ttgcaatact ttattgcgac
    10261 tcacggtgcg cgtaaaggtt tggcggatac cgcgttaaaa accgcgaact ccggttacct
    10321 gacccgtcgt ctggtagacg taactcaaga tttggtcgtt gttgaagacg attgcggtac
    10381 ttcagacggc tttgtcatga aggcagtggt acaaggcggt gatgtgattg aagcattgcg
    10441 cgatcgtatt ttgggccgtg ttactgcgtc tgacgttgtc gatccgtcaa gcggcgagac
    10501 cttggttgaa gccggtacgt tgttgactga aaaactggtg gatatgattg accaatccgg
    10561 tgtcgatgaa gtcaaagtcc gtactccgat tacttgtaaa acccgccacg gtttgtgcgc
    10621 gcactgttat ggtcgcgact tggcgcgcgg taagctggtt aacgccggtg aagcagttgg
    10681 tgtgattgct gcacaatcca ttggtgaacc gggtacccag ttgaccatgc gtacgttcca
    10741 cattggtggt gcggcatccc gtgcggcagc agccagccaa gtggaagcca aatccaacgg
    10801 tacggcacgt ttcagcagcc agatgcgtta cgttgccaac aacaaaggtg agttggttgt
    10861 catcggtcgc tcttgcgaag tcgtgattca tgatgacatc ggccgtgaac gcgaacgcca
    10921 caaagtacct tacggtgcca tcctgctggt acaagacgga gcggccatta aagccggtca
    10981 aaccttggca acctgggatc cgcatacccg tccgatgatc accgaacatg caggtatggt
    11041 gaaatttgag aacgtggaag agggtgttac cgttgcgaaa caaactgacg atgtaaccgg
    11101 tttgtccact ctggtagtga ttgacggtaa acgtcgttcc tctagtgctt ctaaactgct
    11161 gcgtccgact gtaaaattgt tggatgaaaa cggcgtggaa atctgtattc ccggtacgtc
    11221 cactccggtt tcgatggcat tccccgttgg tgcggtgatt accgtacgcg aaggtcagga
    11281 aatcggtaaa ggcgacgtat tggcgcgtat cccgcaagcc tcttccaaaa cccgcgacat
    11341 taccggtggt ctgccgcgcg ttgccgaatt gtttgaagca cgcgtgccga aagatgccgg
    11401 tatgttggcg gaaattaccg gtaccgtttc cttcggcaaa gagaccaaag gcaagcaacg
    11461 tctgattatt accgacgtgg acggcgtagc atacgagact ttgatttcca aagagaaaca
    11521 gattttggta cacgacggtc aagtggtaaa ccgcggcgaa accattgtgg acggcgcggt
    11581 cgatccgcac gatattctgc gtctgcaagg tatcgaagca ctggcacgct acattgtcca
    11641 agaggtgcaa gaggtttacc gtctgcaagg tgtgaagatt tctgataaac acatcgaagt
    11701 catcatccgt caaatgttgc gccgtgtgaa cattgcggat gccggcgaaa ccggcttcat
    11761 taccggagag caggtcgaac gcggcgatgt gatggcggcc aatgaaaaag ctttggaaga
    11821 aggcaaagaa ccggcgcgtt acgaaaacgt attgctgggt attaccaaag cttccctgtc
    11881 taccgacagc ttcatttctg ctgcatcgtt ccaagaaacg acccgtgttc tgaccgaagc
    11941 cgcgattatg ggcaaacaag acgaactgcg cggtttaaaa gagaacgtca tcgtcggccg
    12001 cctgattcct gccggtaccg gtttgactta tcaccgcagc cgtcatcagc aatggcaagg
    12061 ggtagagcag gagactgctg aaacccaagt aacggatgaa taatcttcgg cgcgtttatt
    12121 caatacaaaa ccgcaagctt taagcttgcg gtttttcttt gtccgattaa ggcaaaaaca
    12181 agcgttttcg tcattttgag gcgtgtggat tattccttag gtattttcgg gccggagacc
    12241 aacgaggtgg cgggtgtcgt cggtacgtcc ggagaccaaa ataactttgc cagggatgtt
    12301 ggtttcggcg gtcaaaaaaa gtagcgtctt aatgttttcc atttaaacaa atgtcgtctg
    12361 aaacttcaga cggcatttcc tttaaaaaat aaatatgaaa cccagaaatc tcttttttgc
    12421 aggctgcctg ctgacttcgg cgacgtttgc cgaggatatc ggcgtacctg tcgaactgat
    12481 taacgtcggt aatcggattg cgatgccgtc tgaaggggaa agcctcgccc tcctgccgtt
    12541 tgccgaggat gtaccgccgg ttcgcgatgc aatgccgtct gaagttccta aaagcgcggc
    12601 aggcggcgat gttcggggta accggatggg aatgccgatt aacatcggat gagcgcggct
    12661 ttatggcata aaaaactgtc gtggaaagga tttacacccc aaataaattt ccgttacaac
    12721 aagatcaaca gcaatatgcc cgccttttat tcgcgcagcg gcaaggaacg gtttgtcagt
    12781 atagaaaaaa cgtattgaca gtattttctt cagtcgtccg actgattgtg agggatgtcg
    12841 gtaaatattt atcggcaaac aagaaaatca tctttcttct tgtcgttatg cttgactgta
    12901 tacttgcaat aaaaatataa ttccactctt gccgacatgg tgtcggcaag tatttaactc
    12961 aacaggacga gaaaatatgc caactatcaa ccaattggta cgcaaaggcc gtcaaaagcc
    13021 cgtgtacgta aacaaagtgc ccgcactgga agcctgcccg caaaaacgcg gcgtgtgcac
    13081 ccgtgtatac acgactaccc ctaaaaaacc taactctgca ttgcgtaaag tatgtaaagt
    13141 ccgcctgacc aacggttttg aagtcatttc atacatcggc ggcgaaggcc acaacctgca
    13201 agagcacagt gtcgtattga ttcgcggcgg tcgtgtaaaa gacttgccag gtgtgcgtta
    13261 ccacactgta cgcggttctt tggatactgc aggtgttaaa gaccgtaaac aagcccgttc
    13321 caaatatggt gctaagcgtc ctaaataatt actgggactt aaataggcac gtcggccgcc
    13381 taagcagaac aacggccgag taagtgaata ctcaattggg tattcatggg aatagacccg
    13441 actgaataga ttaaaggaaa ttaaaatgcc aagacgtaga gaagtcccca agcgcgacgt
    13501 actgccagat cctaaattcg gcagcgtcga gttgaccaaa ttcatgaacg tattgatgat
    13561 tgacggtaaa aaatccgttg ccgagcgtat cgtttacggt gcgttggaac agattgagaa
    13621 aaaaaccggc aaagtagcaa tcgaagtatt taacgaagcc attgcaaacg ccaaacctat
    13681 cgtggaagtg aaaagccgcc gtgtaggtgg tgcaaactac caagttcctg ttgaagttcg
    13741 tccttcacgc cgtttggctt tggcaatgcg ctgggttcgc gatgcggccc gcaaacgtgg
    13801 tgagaaatcc atggacctgc gtttggcagg cgaattgatt gatgcgtccg aaggccgtgg
    13861 cggtgcgttg aaaaaacgtg aagaagtaca ccgtatggct gaagccaaca aagcattctc
    13921 tcacttccgt ttctaatttt gaaaggctaa taaaatggct cgtaagaccc cgatcagcct
    13981 gtaccgtaac atcggtattt ccgcccatat cgatgcgggt aaaaccacga cgacagaacg
    14041 tattttgttc tataccggtt tgacccacaa gctgggcgaa gtgcatgacg gtgcggctac
    14101 taccgactac atggaacaag agcaagagcg cggtattacc attacctccg ctgccgttac
    14161 ttcctactgg tccggtatgg cgaaacaatt ccccgagcac cgcttcaaca tcatcgacac
    14221 cccgggacac gttgacttta ccgtagaggt agagcgttct atgcgtgtat tggacggcgc
    14281 ggtaatggtt tactgcgcgg tgggcggtgt tcaaccccaa tctgaaaccg tatggcggca
    14341 agccaacaaa taccaagtgc cgcgcttggc gtttgtcaat aaaatggacc gtcagggtgc
    14401 caacttcttc cgcgttgtcg agcaaatgaa aacccgtttg cgcgcaaacc ctgtacctat
    14461 cgtcattccg gttggtgcgg aagacaactt cagcggtgtg gttgatttgt tgaaaatgaa
    14521 atccatcatt tggaatgaag ccgataaagg tacaaccttt acctatggcg atattcctgc
    14581 cgaattggtc gaaactgccg aagaatggcg tcaaaatatg attgaagccg cagccgaagc
    14641 cagcgaagaa ctgatggaca aatacttagg cggcgacgag ctgaccgaag aagaaatcgt
    14701 aggcgcgttg cgtcaacgta ctttggcagg cgaaattcag cctatgctgt gtggttctgc
    14761 atttaaaaac aaaggtgttc aacgtatgtt ggacgcagtt gtagaattgc tgccagctcc
    14821 taccgatatt cctccggttc aaggtgtcaa cccgaatacc gaggaagccg acagccgtca
    14881 agccagcgat gaagagaaat tctctgcatt ggcgttcaaa atgttgaacg acaaatacgt
    14941 cggtcagctg acctttatcc gcgtttactc aggcgtagta aaatccggcg ataccgtatt
    15001 gaactccgta aaaggcactc gcgaacgtat cggtcgtttg gtacaaatga ctgccgcaga
    15061 ccgtactgaa atcgaagaag tacgcgccgg cgacatcgca gccgctattg gtctgaaaga
    15121 cgttactacc ggtgaaacct tgtgtgcgga aagcgcgccg attatcttgg aacgtatgga
    15181 attccccgag ccggtaatcc atattgccgt tgagccgaaa accaaagccg accaagagaa
    15241 aatgggtatc gccctgaacc gcttggctaa agaagaccct tctttccgtg tccgtacaga
    15301 cgaagaatcc ggtcaaacca ttatttccgg tatgggtgag ctgcacttgg aaattattgt
    15361 tgaccgtatg aaacgcgaat tcggtgtgga agcaaatatc ggtgcgcctc aagtggctta
    15421 ccgtgaaact atccgcaaag ccgttaaagc cgaatacaaa catgcaaaac aatccggtgg
    15481 taaaggtcaa tacggtcacg ttgtgattga aatggaacct atggaaccgg gtggtgaagg
    15541 ttacgagttt atcgatgaaa ttaaaggtgg tgtgattcct cgcgaattta ttccgtctgt
    15601 cgataaaggt atccgcgata cgttgcctaa cggtatcgtt gccggctatc ctgtagttga
    15661 cgtacgtatc cgtctggtat tcggttctta ccatgatgtc gactcttccc aattggcatt
    15721 tgaattggct gcttctcaag cgtttaaaga aggtatgcgt caagcatctc ccgccctgct
    15781 tgagccgatt atggcagttg aagtggaaac cccggaagaa tacatgggcg acgtaatggg
    15841 cgacttgaac cgccgtcgcg gtgttgtatt gggtatggat gatgacggta tcggcggtaa
    15901 aaaagtccgt gccgaagtac ctctggcaga aatgttcggt tactcgaccg acctgcgttc
    15961 tgcaacccaa ggccgcgcta cttactctat ggagttcaag aaatattctg aagctcctgc
    16021 tcacatagct gctgctgtaa ctgaagcccg taaaggctaa tcaggcaaat aggccgtccg
    16081 aaaggctgaa atgatttttc agacggcatt gttctttaat cgatctttaa tgtaaaggaa
    16141 ttagc
//
LOCUS       DAXISH010000050        15671 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.050, whole genome shotgun sequence.
ACCESSION   DAXISH010000050 DAXISH010000000
VERSION     DAXISH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 15671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15671
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.050"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(411..857)
                     /gene="smpB"
                     /locus_tag="ACFOV4_001557"
     CDS             complement(411..857)
                     /gene="smpB"
                     /locus_tag="ACFOV4_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFC7619535.1"
                     /translation="MAIANNKKAFHDFFIEDRIEAGLVLEGWEVKAIRAARVQLKESY
                     IYWKKDAFYLVGCHITALPTASTHIKPDAVRPRKLLLNQSEINKLIGKTERAGYTIVP
                     LDLHFSRGKIKMEIGLAKGKKQHDKRQSMKEADWKREKQRLIKHTR"
     gene            complement(912..1922)
                     /gene="waaF"
                     /locus_tag="ACFOV4_001558"
     CDS             complement(912..1922)
                     /gene="waaF"
                     /locus_tag="ACFOV4_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008920 - lipopolysaccharide
                     heptosyltransferase activity [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase II"
                     /protein_id="HFC7619536.1"
                     /translation="MSIKILIISPSWIGDCVMTQPLFRRLKELHPGCTIDVFAPKWSM
                     AVFERMPEVNEILENPFGHGALELKRRWRVGRDLGRRGYDQVIVLPGSLKSAVIALAT
                     GIAKRTGYVGESRYFLLNDIRRLDKERLPLMVDRYTALAHPSQEDFDGHSGFPEFSID
                     ERRREISVETFGLNLGKPVLAFCPGAEFGPAKRWPTRHFAELGKHYLAAGWQVWLFGS
                     QKDDEIAEEINCLSDGMCVNLCGKTDLSQAMDLLSLADTVVCNDSGLMHLAAALGRKV
                     VAVYGSSSPTHTPPLSDRAKIVSLHLECSPCFKRECPLGHTDCLNRLYPEKIVQAVEE
                     AV"
     gene            complement(2053..2128)
                     /locus_tag="ACFOV4_001559"
     tRNA            complement(2053..2128)
                     /locus_tag="ACFOV4_001559"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2093..2095),aa:Asn,seq:gtt)
     gene            complement(2319..3071)
                     /locus_tag="ACFOV4_001560"
     CDS             complement(2319..3071)
                     /locus_tag="ACFOV4_001560"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFC7619537.1"
                     /translation="MITLPSLNNLPSKWDEIRHCLETRVFECGVMPHPNLTECEAGQF
                     DRDFWDNIGCAPEEYVRIRRAIRLLEVRYPDSLNELVCAAIATPLGEMLAVFGGKGLC
                     LLEFVGQKHLEQEIAAVQKALRGRFVFREDERTQLLRQELDLYFQCRLKTFATPLEMI
                     GTAFQKQAWDALLAIPYGETRSYKEQAQHLGNPKAVRAVAAANGQNKVSVLIPCHRVI
                     GSDGKLTGYAGGLNRKQFLLALERGEVQTALF"
     gene            3382..3906
                     /locus_tag="ACFOV4_001561"
     CDS             3382..3906
                     /locus_tag="ACFOV4_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HFC7619538.1"
                     /translation="MQTRILSAVLLAFSTAAFAGGAFTLQFDNPSEDGGFTQNQLLSA
                     PYGFGCSGDNAPPALSWKNPPAGTKSFVLTVYDKDAPTGLGWMHRVVADIPADVRRRN
                     AASLQLSRCASIADDPSAAISAVISLRICRIRLTPSYTAKPMPSCCNHANTPQSAASA
                     ALCGTSSSVSTAAA"
     gene            complement(4646..5791)
                     /gene="dapE"
                     /locus_tag="ACFOV4_001562"
     CDS             complement(4646..5791)
                     /gene="dapE"
                     /locus_tag="ACFOV4_001562"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009014 - succinyl-diaminopimelate
                     desuccinylase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HFC7619539.1"
                     /translation="MTETQSLELAKELISRPSVTPDDQNCQKLLAERLHKIGFAAEEL
                     HFGDTKNIWLRRGTKAPVVCFAGHTDVVPTGPVEKWDSPPFEPAERDGRLYGRGAADM
                     KTSIACFVTACERFVAEHPDHQGSIALLITSDEEGDALDGTTKVVDVLKARGELIDYC
                     IVGEPTAVDKLGDMIKNGRRGSLSGNLTVKGKQGHIAYPHLAINPVHTFAPALLELTQ
                     EVWDEGNEYFPPTSFQISNINGGTGATNVIPGELNVKFNFRFSTESTEAGLKQRVHAI
                     LDKHGVQYDLQWSCSGQPFLTQAGKLTDVARAAIAETCGIEAELSTTGGTSDGRFIKA
                     IAKELIELGPSNATIHQINENVRLDDIPKLSAVYEGILARLLAGNAV"
     gene            complement(5905..6525)
                     /locus_tag="ACFOV4_001563"
     CDS             complement(5905..6525)
                     /locus_tag="ACFOV4_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HFC7619540.1"
                     /translation="MLTPKSCDLFNIPFFQFAQLKKYQPESIPQIKADYKENWQIWQQ
                     LIQQVAAELGAPFAPPHIERWCNGWQVRAHFFAYFKYEQYKNSAAILSILLNRRRLSV
                     SLDWHCYKADVSPIALPDYNRWLDNFDTEKYASFDMWHGAESEYDDYRTVAQQNESDR
                     RLQNDEDFFCIGKHIERDDLGRQDVAKWIAETVEDLLPLYEACHGK"
     gene            complement(6559..7068)
                     /locus_tag="ACFOV4_001564"
     CDS             complement(6559..7068)
                     /locus_tag="ACFOV4_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HFC7619541.1"
                     /translation="MNPFETKSVTFAEPIEMLYACHGKVRRFCGQVAMLSDYIAENGC
                     NQIVLQTIRQIAQYFNVAAPLHHEDEEENFFPLLLQYAPQAQESVDELLRQHIGLHDN
                     WAAVSAEFAKLEADNAYVPDEEAFKRFVAGYDVHLAIEEPLFDMGNTFIPKEKLTEIG
                     EIMAARRRK"
     gene            complement(7163..7714)
                     /gene="azu"
                     /locus_tag="ACFOV4_001565"
     CDS             complement(7163..7714)
                     /gene="azu"
                     /locus_tag="ACFOV4_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="azurin"
                     /protein_id="HFC7619542.1"
                     /translation="MKTYLALISAAVIGLAACSQEPAAPAAEATHAAEAPASEAPAAE
                     AAPADAAEAPAAGNCAATVESNDNMQFNTKDIQVSKACKEFTITLKHTGTQPKASMGH
                     NLVIAKAEDMDGVFKDGVGAADTDYVKPDDARVVAHTKLIGGGEESSLTLDPAKLADG
                     EYKFACTFPGHGALMNGKVTLVD"
     gene            complement(7995..8417)
                     /locus_tag="ACFOV4_001566"
     CDS             complement(7995..8417)
                     /locus_tag="ACFOV4_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DciA family protein"
                     /protein_id="HFC7619543.1"
                     /translation="MNLEQLGRRDALLSGLLKQAGQWRRLDAAVKKLLPANLHPHFQT
                     ACIEDGRLVLLAANNMAASRLKMIAPSVLPQLAGLDASIRSVSVRLAPKPEKPPKTNT
                     LHLSKAALESFGSAAVKLEKRHPELAEALANLVRRHGA"
     gene            8548..11298
                     /gene="secA"
                     /locus_tag="ACFOV4_001567"
     CDS             8548..11298
                     /gene="secA"
                     /locus_tag="ACFOV4_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFC7619544.1"
                     /translation="MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQ
                     AKTAEFKQRLADGQTLDGILPEAFAVCREASRRTLGMRHFDVQLIGGMVLHDGKIAEM
                     RTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISD
                     MQPFDRQNAYAADITYGTNNEFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDE
                     ARTPLIISGQADDNIQLYQIMNTVPPHLVRQETEEGEGDYWVDEKAHQVILSEAGHEH
                     AEQILTQMGLLAENDSLYSAANIALMHHLMAALRAHTLFHKDQHYVIQDGEIVIVDEF
                     TGRLMSGRRWSEGLHQAVEAKEGVEIKRENQTLASITFQNYFRLYTKLSGMTGTADTE
                     AFEFQSIYNLETVIIPTNRPIQRKDFNDQIFRSAEEKFEAVVKDIEECHKRGQPVLVG
                     TTSIENSELVSHLLQKAGLPHNVLNAKEHEREALIVAQAGKVGAITVATNMAGRGTDI
                     VLGGNLKHQTDAIRADETLSDEEKQAQIAALENGWQAEHDKVMEAGGLHIIGTERHES
                     RRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLFALDRAAAILNRLAPERGVAIEHNL
                     LTRQIEGAQRKVEGRNFDMRKQVLEYDDVANEQRKVIYSQRNEILTSKDISDLMQEIR
                     SDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHEDIQSWLKADNAIDGQDIKER
                     LIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREHLAAMDYLRQGIHLRSYAQ
                     KNPKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAVVEEQPIGNIQSIHSES
                     PDMEELLGQSQTDLVTEAFNPDGTDFSPEALEARGQIVHRNDPCPCGSGLKYKQCHGK
                     LA"
     gene            11442..13214
                     /gene="dnaG"
                     /locus_tag="ACFOV4_001568"
     CDS             11442..13214
                     /gene="dnaG"
                     /locus_tag="ACFOV4_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFC7619545.1"
                     /translation="MIPSDFIDELLAKTDIVDIIDEQVPLKKGGANYMACCPFHKEKT
                     PSFSVSPTKQFYHCFSCGAHGSAIGFVMEHQGLSFPEAVQFLADRVGMIVPKVRGQND
                     NPEVRAERKKKQQTLEETTAAAADFYAQQLKFNPTAKAYLDKRGLSAEVIAHYGLGYA
                     PDGWQPLAQVFQPYPNTALVDTGMVIDNEGRYYDRFRHRIMFPIRNPRGQVIGFGGRV
                     LDDSKPKYLNSPDTPLFDKGKNLYGLYEGRAAVKEAERILVVEGYMDVVALAQFGVGY
                     GVAALGTATTAEHVKILMRQADSIYFCFDGDSAGRKAAWRALENALPQLKDDKSLHFL
                     FLPEEHDPDSYIRAYGKAQFEDALLNQSKPLSEYFWEHLSDGIHLNTQEGKAELVKTS
                     SPLLAQITAPALAYLLKQRLSELVGIDPDNLAQLLGQEAPKRHVKQKNYKLPPISVKQ
                     PVMLTLVQRQIRSLLINPDWAAYIDLPDYLALDGDFACLANLAESIKNHAAVPETAQV
                     LEYMRGSPYEETITRIFHSTHQSEEMNSSSEEDCENFQIGMKKLLNELKYSQIEALKQ
                     KSLQSGLNESEKKLLLSLLTAKQN"
     gene            13401..15329
                     /gene="rpoD"
                     /locus_tag="ACFOV4_001569"
     CDS             13401..15329
                     /gene="rpoD"
                     /locus_tag="ACFOV4_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFC7619546.1"
                     /translation="MSRNQNHEEYQDDTRPLSIEEQRARLRQLIIMGKERGYITYSEI
                     NDALPDDMSDADQIDNIVSMISGLGIQVTEHAPDAEDILLSDNAAVTDDDAVEEAEAA
                     LSSADSEFGRTTDPVRMYMREMGQVDLLTREDEIIIAKKIENALKNMVQAISACPGSI
                     AEILELIEKIRKDEIRVDEVVEAIIDPNEVLLNELGLGHLETTAPEKPSNDNSDENED
                     DEESEEDADEISAANLAELKQKVIGHFAQIEKDYKKMIGRLEKHHSRHKDYLAYRDAI
                     ANKLLEVRFATRQIDSLSSSLRGKVENIRKLEREIRDICLDRVHMERDYFIQNFLPEI
                     TNLEWIEEEIAKGRVWSDALDRFRHAILEKQTELADMEKETRISIEELKEINKNMVSS
                     EKETAAAKQEMIQANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYK
                     FSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQHLQETGEEPDSAKLA
                     ELMQMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDANNVAPADAAMYTSLHE
                     VTKEILESLTPREAKVLRMRFGIDMNTDHTLEEVGRQFDVTRERIRQIEAKALRKLRH
                     PTRSDRLRSFLDSEDSKL"
     gene            15476..>15671
                     /locus_tag="ACFOV4_001570"
     CDS             15476..>15671
                     /locus_tag="ACFOV4_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC7619547.1"
                     /translation="MSTFFQQTAQAMIAKHIDRFPLLKLDQVIDWQPIEQYLNRQKNR
                     YLRDHRGRPAYPLLSMFKAVL"
BASE COUNT         4041 a         4426 c         3767 g         3437 t
ORIGIN      
        1 gattttttaa acttctgctt gcttgcttcg agtttcataa aaaattttcc tttgtcaagt
       61 aaaaataaat ggggcgtgga ttttagcata aaactgaaca aaaaatgtca tttagctcac
      121 atttttctct atttatttct tatttattaa aggtaaacgt ttgctttttg ctattttgtc
      181 aagccagttt gaaaatgtgt ataattgccc tcgttattta caaaaatttc aggaaaaatg
      241 accgcacttt acccttggct aatgccaatt tatcatcaaa ttgctcaaac ctttgacgaa
      301 ggtttggggc atcatgctgt gctgattaaa gcggatgctg gtttaggtgt agaacgttta
      361 cacatcaggc ggcagccttg cccataccct ctgaagcact gtttccacaa tcagcgcgta
      421 tgcttaatca accgctgttt ctcgcgtttc caatccgcct ctttcatact ctgacgtttg
      481 tcgtgctgtt tcttaccttt tgccaaaccg atttccatct tgatttttcc gcgcgaaaaa
      541 tgcaaatcca gcggcacgat ggtgtagccg gcacgttcgg ttttgccgat taatttgttg
      601 atttccgact ggttcaacaa gagcttgcgc ggacgtacgg catctggttt aatgtgtgtc
      661 gaggctgtgg gcaaagccgt aatatggcag ccgaccagat aaaacgcgtc ttttttccaa
      721 tagatataac tctctttaag ctgtacgcgc gcggcgcgga ttgctttgac ttcccagcct
      781 tccaagacca aaccggcttc aatccggtct tcaatgaaaa aatcgtgaaa tgctttttta
      841 ttgttcgcaa tagccataaa catcctatca atatccgccg tcagacggca taaacccgaa
      901 aacagaaccc atcataccgc ctcttcaacc gcctgcacaa tcttctcggg atacagcctg
      961 ttgaggcagt cggtatgccc cagcggacat tcccgcttaa aacagggcga acattccaag
     1021 tgcaggctga cgattttcgc cctgtcgctc aaaggcggcg tatgcgtcgg gctggaagaa
     1081 ccgtaaaccg ccaccacctt cctgcccaat gccgccgcca agtgcatcag cccgctgtcg
     1141 ttgcacacaa ccgtgtccgc caacgacagc aaatccattg cctgcgacaa atcggttttg
     1201 ccgcacaaat tgacacacat accgtctgaa aggcagttga tttcctcggc aatttcatca
     1261 tctttttgcg aaccgaacag ccaaacctgc caacccgccg ccagataatg tttgcccaac
     1321 tcggcaaaat gccttgtcgg ccaacgcttt gccggcccga attccgcgcc cgggcaaaat
     1381 gccaaaacag gctttccaag attcaaaccg aaagtttcga cagaaatttc ccgccgccgt
     1441 tcatcaatgg aaaactcggg gaatcccgaa tgcccgtcaa aatcttcctg actcggatgc
     1501 gcgagagccg tatatctgtc caccatcaaa ggcagacgtt ccttatccag cctgcgtata
     1561 tcgttcaaca gaaaataacg gctttcaccg acataacccg tccttttggc aatacccgtt
     1621 gctagcgcga tgactgccga tttcaaagaa ccgggcaaca cgataacctg atcgtatccg
     1681 cgccgcccca aatccctgcc gacccgccag cggcgtttca actccaacgc accgtgtccg
     1741 aacggattct caagaatttc attcacttcc ggcatacgct cgaacaccgc catcgaccac
     1801 ttcggcgcga acacatcaat cgtgcaaccg gggtgaagtt ccttcaaacg gcggaacaag
     1861 ggctgggtca tcacgcagtc gcctatccaa ctgggagaaa taatcaggat tttgatggac
     1921 ataacaagaa accgaaatca gacaggcaga attttaccgc gaaaccgttg gaaaacctat
     1981 cttgtctcat tccgaacgcc gtacgtgcaa atatgaaaaa gcccgaacat tcaagttcgg
     2041 gcttcaaaat tctggctccc cgacctgggc tcgaaccagg gacctgcgga ttaacagtcc
     2101 gtcgctctac cgactgagct atcggggaat ggggcgtatt atagcgtccg gaaaaaatgt
     2161 gtcaatcctt aattttggaa aaatgggcga caaaacgaca agcatatgaa tcagaaagac
     2221 attaagaccg atgccttaaa aggattgccg ttgtatgaat ttccacagcc gtcatcacac
     2281 catatttaag cccgatgagc cgttctgccc tcccccgctt aaaacaatgc cgtctgaact
     2341 tcgccgcgtt ccaaagccag taaaaactgt ttgcggttca aaccgcctgc gtagccggtc
     2401 agtttgccgt cgctgccaat gacgcggtgg cagggaatca ggacagacac cttgttctgc
     2461 ccgttggcgg cggcaacggc gcggacggct ttggggttgc ccaaatgctg cgcctgttcc
     2521 ttgtagctgc gcgtttcacc gtaaggaatc gccaaaagcg cgtcccacgc ctgtttttga
     2581 aacgccgtac caatcatttc caaaggcgtg gcaaaggttt tcagacggca ttggaaatac
     2641 aaatccaatt cctgccgcaa aagttgcgtc cgctcatcct cccgaaacac aaaccgtccg
     2701 cgcaaggctt tttggacggc ggcaatttcc tgttccaaat gcttctgccc gacaaattcc
     2761 agcaaacaca agcctttacc gccgaacacc gccagcatct cgcccaaagg cgtggcaatg
     2821 gcggcacaca ccagctcgtt caagctgtcg ggataacgca cttccaacag acggatggct
     2881 cggcggatac ggacatattc ttcaggcgcg cagccgatat tgtcccaaaa atcccgatcg
     2941 aactgcccgg cttcgcattc cgtcagattg ggatgcggca taacgccgca ctcaaaaacc
     3001 cgggtttcga ggcaatggcg gatttcatcc cattttgacg gcagattgtt taaggaaggc
     3061 agggtaatca ttcgtttgct ccgtatctct atcatggatt tggcggcaaa atccccaatt
     3121 ctcgtcattc ccgcacgccg atgcaggaac gggctatgac gtaaatcttg agggttgggt
     3181 tgcggcaatg cctaaatatg cgatatttct aaagcctcag ggaaaggaat taaagacttc
     3241 agacgacctg caaagggtcg tctgaaacca cgatttttgc atttacgcat tccggcacat
     3301 catccaaccg tttcggcaca ttcctgccgc cgttgacagc ctataatgaa tccacttatt
     3361 catcaagcaa aggaatcatc tatgcaaacc cgcatcctct ccgccgtact gctggctttt
     3421 tcaaccgctg cctttgccgg gggcgcattc acgctgcaat tcgacaaccc gtccgaagac
     3481 ggcggcttca cgcaaaacca gcttttgagt gcgccttacg gcttcggctg ttcaggcgac
     3541 aatgctccgc ccgcgctgtc gtggaaaaat ccgcccgccg ggacaaaaag tttcgtcctg
     3601 accgtttacg ataaagacgc gccgaccgga ctgggctgga tgcaccgggt ggtcgccgac
     3661 attcccgccg atgtccgccg ccgcaatgcg gcctcgctgc aattaagccg ctgcgccagc
     3721 atcgccgacg acccgtccgc agccatatcg gcggtaatca gtttgcggat ttgccgcatc
     3781 aggttgacgc cttcgtacac ggcaaaaccg atgccgtcat gctgcaacca cgccaacacg
     3841 ccgcaaagcg cggcctccgc cgcattgtgc ggcacttctt catccgtcag caccgccgcc
     3901 gcataatcaa acgccgcgcc catccgccca gggtgcggca gcttcaccgc atcgcacact
     3961 gcctgcgccg tcccgtattg tgcggcaaac ctttctacgg tttcctgttc gaaagcaatc
     4021 cattgcgcct gatagaggcc gtctgaatcg ggaatattaa taacgtcaaa cgtctgtccg
     4081 cctgccaacg caaccgcctc acccgccgca atcctcaatt cgcgcctcgc ccaccgcagc
     4141 ttcttgcttc cgcgccgcac gataagcaca gctggttcat ataccgccac gctgcggtac
     4201 aaggcggtat gatgttgcac gatgccgccc aaagcaccca atcgttcgcg cgtatgaaag
     4261 taatttgacg gcactattat ctccaacacg cagggccgca cataaggcgc agccctgttt
     4321 accctgattt ggaaggggtt acttcccaaa aataaaccaa aatcccactg ccccgaatgg
     4381 ccgagtttca accatattcc gtcggtgtgc ctgcaacttg actccctccc ctgtggggga
     4441 gggttgggga gagggtaaaa cggggcagat acagacaata tttccgttac cgccccgatg
     4501 ccctctccct aaccctctcc cacgggagag ggaatggatt gccgttgaaa taaatcgctc
     4561 tacataaaaa atcaatgtgt tatctcaaac ccacgttagg tctaagcaaa tggtcggaca
     4621 tccgtatccg gcaagcaagc tgctttcaga cggcatttcc agccaacaag cgcgccaata
     4681 tcccctcata caccgcagac agcttcggaa tatcgtccag ccgcacgttt tcgttgattt
     4741 ggtggatggt ggcattggac gggcctaatt cgatgagttc ttttgcaatg gctttgatga
     4801 agcgtccgtc cgaagtgccg ccggtggtgg acaattcggc ctcaatgccg caggtttcgg
     4861 caatggctgc gcgtgccacg tcggtcagtt tgcccgcttg ggtcagaaag ggctgccccg
     4921 aacacgacca ctgcaaatcg tattgcacgc cgtgtttgtc caaaatggcg tggacgcgtt
     4981 gtttcagccc tgcttcggtg gactcggtgg agaagcggaa attgaatttg acgttcaact
     5041 cgcccggaat gacattggtc gcgcctgtgc cgccgttgat attggaaatt tgaaagctgg
     5101 ttggcgggaa atattcgttg ccttcgtccc agacttcctg cgtcagctct aacaaggccg
     5161 gggcaaaagt atgcacggga ttgattgcca aatgcggata ggcaatatgg ccttgcttgc
     5221 ctttgacggt caggttgccc gacagcgagc cgcgccggcc gtttttaatc atatcgccca
     5281 atttgtccac ggctgtcggt tcgccgacga tgcagtagtc aatcaactcg ccgcgcgctt
     5341 tcaacacatc gacgactttg gtcgtgccgt ccagcgcgtc gccctcttcg tcggaagtaa
     5401 tcaggagcgc gatgctgcct tgatgatcgg ggtgttcggc aacaaagcgt tcgcaggcgg
     5461 taacgaaaca ggcgatgctg gttttcatgt ccgccgcacc gcgcccgtat aatcttccgt
     5521 cgcgctcggc cggctcgaac gggggcgaat cccatttttc gacagggcct gtcggtacaa
     5581 cgtcggtatg ccctgcaaaa cagacgacgg gagctttcgt gccgcgtcgc aaccagatgt
     5641 ttttggtgtc gccgaaatgg agttcttcag ccgcaaaacc gattttgtgc aggcgttcgg
     5701 caaggagttt ttggcaattt tggtcgtcgg gggtaacgga tgggcgggaa atcaattctt
     5761 tggcgagttc tagggattgg gtttcggtca tatttgttca cttttgaaat tagaccatct
     5821 gaaacgttct gaatgtgatt ttcagacggc atttaggtta ggttggcata cggggtgggt
     5881 atttttaccc gtcagtcttc tgaatcattt gccgtgacac gcttcgtaaa gcggcagcaa
     5941 atcttccacc gtttccgcta tccatttcgc gacatcctgc ctgcccaaat cgtcgcgttc
     6001 gatgtgtttg ccgatgcaga agaaatcttc gtcgttttgc aaccttcggt cggattcatt
     6061 ttgctgcgcg acagtgcggt agtcgtcgta ttcgctttcc gcgccgtgcc acatatcgaa
     6121 agaagcgtat ttttcagtat caaaattatc caaccaacgg ttgtaatcag gcagcgcaat
     6181 cggcgacacg tcggctttgt agcaatgcca gtccaagctg acactcaaac ggcggcggtt
     6241 gagcagtatc gacaaaatcg cggcggaatt tttatattgt tcgtatttga agtaggcaaa
     6301 gaaatgggcg cgaacctgcc agccgttgca ccagcgttcg atgtgcggcg gcgcaaacgg
     6361 cgcacccaat tcggcggcaa cctgctgaat cagctgctgc catatctgcc agttttcctt
     6421 gtagtcggct ttgatttgcg gaatgctttc aggctggtat tttttaagct gggcaaactg
     6481 gaaaaacggg atattgaaca aatcgcaact tttcggggtc agcataatat atccttgaga
     6541 cgattgtttc agacggcatt atttgcgccg gcgcgccgcc ataatttcgc cgatttcggt
     6601 cagtttttct tttgggataa aggtgttgcc catatcaaac agcggctctt caatcgccaa
     6661 atgaacatca tatcccgcca caaaacgttt gaacgcttcc tcatcgggga cataagcgtt
     6721 gtctgcttcg agtttggcaa attcggcgga aacagccgcc cagttgtcgt gcagcccgat
     6781 atgttggcgc aaaagctcgt ccacgctttc ttgggcttgc ggcgcatatt gcagcagcag
     6841 cgggaagaag ttttcttctt cgtcttcatg gtgcagcggc gcggcaacgt tgaaatactg
     6901 ggcgatttgg cggatggttt gcaaaacaat ctgattgcag ccgttttcgg cgatatagtc
     6961 cgacagcatg gcgacttgtc cgcaaaaacg gcgcactttg ccgtggcagg catacagcat
     7021 ttcaatcggt tcggcaaagg taacgctttt ggtttcaaac ggattcatgt tttcgttctc
     7081 aacgggcact tttcaagcag tcattttata ataaaacagc ctgcacaaag caggctgtcc
     7141 gtcttttgag actttaagcg gattaatcga ccaaagtcac tttgccgttc atcaaagcac
     7201 cgtgacctgg gaaggtacaa gcgaatttgt attcgccgtc agccagtttg gcaggatcca
     7261 aagtcaggga agactcttcg ccgccgccga tcagtttggt gtgggcaaca acgcgcgcat
     7321 cgtcaggttt gacatagtcg gtatcggcag cacctacgcc gtctttaaat acgccgtcca
     7381 tgtcttcagc tttggcaatc acaaggttgt gacccatgct ggctttgggt tgcgtaccgg
     7441 tatgtttcag agtgatggtg aactctttac atgctttgct gacttggatg tctttggtgt
     7501 tgaactgcat attgtcgttg gattcgacag ttgccgcaca gttgccggca gcaggggctt
     7561 cggcagcatc tgcaggagca gcttcggcgg caggtgcttc ggaagcgggt gcttcagcag
     7621 catgagttgc ctcggcagca ggcgcggcag gttcttgaga gcaggcagcc aaaccgataa
     7681 cggcagcaga aatcagagcc agatacgttt tcataacaaa tctccaatcg ataaaataat
     7741 attcggtttt acggaaatca aagtgcaacc gccattaaca aaaccttgaa aaagattccg
     7801 ccgcgttgca caaacagatg tttcggggcg gcattttgct acaaatttca tttgaaatca
     7861 aagcctgtct gcaagtttac aatcgtttac tttaaaaggg gcaattttac cccgaaccta
     7921 tttctttagt attagaccca ttatccttta cttcttaata ttaacggatg tttacacaaa
     7981 ttcccgtata cattttatgc gccatgcctt ctaaccaagt ttgccaatgc ctccgccaat
     8041 tcgggatgcc gtttttccaa ctttaccgcc gccgaaccga aactctccag cgcagcctta
     8101 ctcaaatgca gggtattggt tttcggcggt ttttccggtt tcggggccag cctgaccgaa
     8161 acagagcgta tcgaagcatc aagccctgcc aactgcggca ataccgacgg tgcaatcatt
     8221 ttcaagcgcg atgccgccat attgtttgcc gccaaaagga caagcctgcc gtcttcgata
     8281 catgccgtct gaaaatgcgg gtgcaggttg gcaggcagca gttttttcac ggcggcatcc
     8341 aaccgccgcc actgtcccgc ctgtttcaaa agtccggaaa gcagcgcgtc ccgcctgccc
     8401 aactgttcca aattcataaa acatacaccc aaaaagattg aaataccgca aacgcgcctt
     8461 tatttcagac ggcattagca ctttgcacaa acgcttgtgt taaaatcgcg ttttcgccca
     8521 ctattatatc aggcgcagga attattcatg ctgacaaaca ttgccaagaa aatcttcggc
     8581 agccgcaacg accgcttgct gaaacaatac cgtaaatccg ttgccagaat caacgcgctc
     8641 gaagaacaga tgcaagccct aagcgatgct gatctgcaag ccaaaactgc cgaattcaaa
     8701 caacgcctcg ccgacggtca gactttggac ggcattttgc ccgaagcctt cgccgtctgc
     8761 cgcgaagcgt cccgccgcac cctcggtatg cgccacttcg acgtgcagct tatcggcggt
     8821 atggtgctgc atgacggcaa aatcgccgaa atgcgtaccg gcgaaggcaa aaccctggtc
     8881 gccaccctcg ccgtctatct caacgcgctg gccggcaaag gcgtacacgt cgttaccgtc
     8941 aacgactacc tcgcctcacg cgatgcgggc atcatggaac cgctctataa tttcctcggc
     9001 cttaccgtgg gcgtgattat ttcagatatg cagccgttcg accgtcaaaa cgcctatgcc
     9061 gccgatatca cctacggcac caataatgaa ttcggcttcg actacctgcg cgacaatatg
     9121 gttaccgacc aatacgacaa agtgcagcgc gaattgaatt ttgccgttgt cgatgaagtg
     9181 gattccatct tgattgacga agcgcgcact ccgctgatta tctccggcca ggcagacgac
     9241 aacatccagt tgtaccaaat catgaacacc gtcccgcccc acctcgtccg ccaagagaca
     9301 gaagaaggcg aaggcgacta ctgggtagat gaaaaggcgc accaggtcat cctgagcgaa
     9361 gccggccacg aacacgccga gcagattctg acccaaatgg gattgctggc agaaaacgac
     9421 tcgctctatt ctgccgccaa catcgccctg atgcaccacc ttatggcggc attgcgcgcg
     9481 catacgttat tccacaaaga ccaacattac gttatccaag acggcgaaat cgtcatcgtt
     9541 gacgaattta caggccgtct gatgtccggc cgccgctggt ccgaaggcct gcatcaagcc
     9601 gtggaagcca aagaaggcgt ggaaatcaaa cgcgaaaacc aaaccctcgc ctccatcacc
     9661 ttccaaaact atttccgcct gtacaccaag ctctccggca tgaccggcac agccgatacc
     9721 gaagccttcg agttccaaag catctacaac ctcgaaaccg tcatcatccc gaccaaccgc
     9781 cccatacaac gcaaagactt caacgaccag attttccgtt ccgccgaaga aaaattcgaa
     9841 gccgtcgtca aagacatcga agaatgccac aaacgtgggc agcccgtcct cgtcggcaca
     9901 accagcatcg aaaactccga actggtctcc catcttttgc aaaaagccgg tctaccgcac
     9961 aacgtcctca acgccaaaga acacgaacgc gaagccctga ttgtcgccca agctggcaaa
    10021 gtcggcgcga ttaccgttgc caccaatatg gcgggacgcg gtacggacat cgttttaggc
    10081 ggcaacctga agcaccaaac cgatgccatc cgtgccgacg aaaccttgag cgacgaagag
    10141 aaacaggcac aaatcgccgc actcgaaaac ggctggcagg cagaacacga taaagtaatg
    10201 gaagcaggcg gcctgcacat catcggtacg gaacgccacg aaagccgccg tatcgacaac
    10261 caattgcgcg gacgttccgg ccgtcagggc gaccccggat ccagccgttt ctacctttcg
    10321 tttgaagacc cgctgctgcg cttattcgca ctcgaccgcg ccgccgccat cctcaaccgt
    10381 ctcgcccccg aacgcggcgt tgccatcgaa cacaacctgc tgacgcgcca aatcgaaggg
    10441 gcgcaacgca aagtcgaagg cagaaacttc gatatgcgca aacaggtttt ggaatacgac
    10501 gacgttgcca acgaacagcg caaagtcatt tacagccagc gcaacgaaat tctgaccagc
    10561 aaagacatca gcgacctgat gcaggaaatc cgttctgatg tcgtcagcga cctcgtggat
    10621 acctatatgc cgcccgacag catggaagaa caatgggaca tcccgacttt ggagaaccgt
    10681 ctggctgccg aattcagact gcacgaagac atccaatcct ggctgaaggc ggacaatgcg
    10741 attgacggtc aagacatcaa agaacgcctg atcgaacgca tcgaaaacga atatgccgcc
    10801 aaaaccgaac tggtcggcaa gcaggcaatg gccgatttcg agcgcaacgt gatgttgcag
    10861 gtcatcgaca accaatggcg cgaacacctc gccgctatgg actacctgcg acaaggcata
    10921 cacctgcgca gctatgccca aaaaaatccg aagcaggaat ataaacgtga agcctttacc
    10981 atgttccaag acctgtggaa cggcatcaaa ttccatattg cctccctgct tacctcggtt
    11041 caaatcgaac aaaaccctgt cgcggtggtt gaagagcaac ccatcggcaa catccagtcc
    11101 atccattccg aatcgcccga tatggaagaa cttttgggtc agtcgcaaac cgatctggtt
    11161 accgaagcct ttaatcccga tgggacggat ttcagccccg aagccttgga agcgcgggga
    11221 caaatcgtcc accgcaacga cccctgcccc tgcggcagcg gtttgaaata caaacaatgc
    11281 cacggcaaac tggcttgagc gtttgaacgc aaatgccgtc tgaacatccg gtttccggct
    11341 tcagacggca ttttgcctga accgccacat ccgaccgcca ttccgaaaaa tcccgatttc
    11401 gtaccgtcca aactaaaaac aggcatccgc cccgccgaac tatgattcca tccgacttca
    11461 ttgacgaact tctggccaaa accgatattg tcgacatcat cgacgaacag gttccgctga
    11521 aaaaaggcgg ggcgaactat atggcgtgtt gcccgttcca caaggaaaaa acgccgtcgt
    11581 tttcggtcag tccgaccaag cagttttacc actgtttcag ttgcggggcg cacggttcgg
    11641 cgattggttt tgtgatggaa catcaggggc tgtcgtttcc ggaggcagtg cagttccttg
    11701 ccgaccgcgt gggtatgatt gtgcctaaag tgcgcgggca gaacgataat cccgaagtcc
    11761 gtgccgaacg taagaaaaag cagcagacgc tggaagaaac gacagcggcg gcggctgatt
    11821 tttatgcgca acagttgaaa ttcaatccga cggcgaaggc ttatttggac aagcgcggct
    11881 tgagcgcgga agtcatcgcg cattatggtt tgggctacgc gcccgacggc tggcagcctt
    11941 tggcgcaagt attccaaccg tacccgaata ccgcgttggt ggatacgggt atggtgattg
    12001 acaatgaggg gcggtattac gaccgattcc gtcatcggat tatgttcccc atccgcaatc
    12061 cgcgcgggca ggtcatcggt ttcggcggca gggtactgga cgactccaaa cccaaatatc
    12121 taaactctcc cgatacgcct ttgtttgata aggggaaaaa cctttacggc ttgtatgagg
    12181 ggcgtgccgc tgtcaaggaa gcggagcgga ttctggtggt cgaaggctat atggacgtgg
    12241 tcgcgctggc acagttcggc gtgggctacg gtgtggcggc cttgggcacg gcaacaacag
    12301 ctgaacacgt caaaatccta atgcgtcagg cggacagtat ttatttctgt ttcgacggcg
    12361 acagcgcggg gcgcaaagcg gcttggcgcg cgctggaaaa cgcgttgccg cagttgaaag
    12421 acgacaaatc gctgcatttt ttgttcctgc ccgaggaaca cgaccccgac agttacatcc
    12481 gtgcctacgg caaagcgcaa tttgaagacg cgcttctgaa tcaaagcaag cctttgtcgg
    12541 agtatttctg ggaacacctt tcagacggca ttcatctcaa tacgcaggaa ggcaaggcgg
    12601 aattggtaaa aaccagttcg ccgcttttgg cgcagattac cgcgccggca ttggcttatt
    12661 tgttaaaaca acggcttagc gaactggtcg gcatcgaccc cgacaacctc gcgcaactgc
    12721 taggacagga agcgccgaag cggcacgtca aacaaaaaaa ctacaaactg cctccgattt
    12781 ccgtcaaaca gcccgtcatg ctgacgctgg tacagcggca aatccgcagc ctcttgataa
    12841 atccggattg ggctgcatat atagacctgc ccgattatct ggcgttggac ggtgatttcg
    12901 cctgccttgc caatcttgcc gaatcgatta aaaaccatgc cgccgtaccc gaaaccgctc
    12961 aggttttaga gtatatgcgc ggctcgcctt acgaagaaac gataacccga atcttccatt
    13021 caacgcacca atcggaagaa atgaacagca gcagtgaaga agattgcgag aatttccaaa
    13081 tcggcatgaa aaaactgctc aatgagttaa aatacagcca aatcgaagca ttgaaacaaa
    13141 aaagcctgca atccggctta aatgaaagcg agaaaaaact tttgctgtcg ttgctgaccg
    13201 caaaacaaaa ttgaccggcg gattccgcca cccgtaaacc cgttatgccg tctgaaaagc
    13261 acttaccccg gctgcaacaa cgacacctgc agaacaccca tcccaaaaag ccttcagacg
    13321 gcatcagagt acccgctctg ccacgccttc aggtgcgttc aaacgcaaac cgtcggcacc
    13381 ttaccaacag aaagcagaca atgtccagaa accaaaatca cgaagaatat caagacgaca
    13441 cccgtccgtt aagcattgaa gagcaacgcg cgcgcctgcg tcagctcatc atcatgggta
    13501 aagaacgcgg ctacatcacc tactccgaaa tcaacgacgc cctgccagac gatatgtctg
    13561 atgccgacca aatagacaat atcgtcagca tgatttccgg tttgggcatc caagttaccg
    13621 aacacgcccc cgatgcggaa gacatattgt taagcgacaa tgccgccgtt accgacgatg
    13681 atgccgtcga agaagccgag gccgcccttt ccagtgcaga ttccgagttc ggcagaacca
    13741 ccgaccccgt ccgtatgtat atgcgcgaaa tggggcaggt cgacctgctg acccgcgaag
    13801 acgaaatcat catcgcaaaa aaaattgaaa acgccctgaa aaatatggtt caggccatct
    13861 ccgcctgccc gggatccatt gcggaaatct tagaactcat cgaaaaaatc cgcaaagacg
    13921 aaatccgcgt cgacgaagtc gtagaagcca ttatcgaccc gaatgaagta ttgctcaacg
    13981 aattgggctt ggggcacttg gaaaccacag cgcccgagaa accttccaac gacaattcgg
    14041 acgaaaacga agacgacgaa gaatcggaag aagatgcgga tgaaatctcg gcagccaatc
    14101 tcgccgaatt gaaacaaaaa gtcatcggcc actttgccca aatcgaaaaa gactacaaaa
    14161 aaatgattgg ccgtttggaa aaacaccaca gccggcacaa agactatctc gcctaccgcg
    14221 acgcgattgc caacaaactg ctggaagtcc gtttcgccac ccggcaaatc gacagcctca
    14281 gcagcagcct gcgcgggaaa gtagaaaaca tccgcaaact cgaacgcgaa atccgcgaca
    14341 tctgcctcga ccgcgtccat atggaacgcg actacttcat ccaaaacttc ctgcccgaaa
    14401 tcaccaatct agaatggatt gaagaagaaa tcgccaaagg cagggtttgg agcgacgcgc
    14461 tcgaccgctt ccgccacgcc atcctcgaaa aacaaaccga gttggcggat atggaaaaag
    14521 aaacccgcat ttccatcgaa gagttgaaag aaatcaacaa aaatatggtg tcaagcgaaa
    14581 aagaaaccgc agccgccaaa caggaaatga ttcaggcaaa cttgcgcctc gtgatttcca
    14641 tcgccaaaaa atataccaac cggggcttac aattccttga tctgattcag gaaggcaaca
    14701 tcggtttgat gaaagcggtc gataagttcg aataccgcag aggctataaa ttctccacct
    14761 acgcaacctg gtggatccgc caggcaatta cacgctcgat tgccgatcag gcgcgtacca
    14821 tccgcattcc ggtacatatg attgaaacca tcaacaagat gaaccgcatc tcgcgccaac
    14881 accttcaaga aaccggcgaa gaacccgatt ccgccaaact tgccgaactg atgcagatgc
    14941 ccgaagacaa aatccgcaaa atcatgaaaa tcgccaaaga gccgatttcg atggaaaccc
    15001 ccatcggcga cgacgacgat tcgcacttgg gcgacttcat cgaagatgcc aacaatgttg
    15061 cgccggccga tgcggcaatg tacaccagcc tgcacgaagt aaccaaagaa atcctcgaaa
    15121 gcctgacacc gcgtgaggca aaagtcctgc gtatgcgttt cggcatcgat atgaacaccg
    15181 accacacgct ggaagaagtc ggcagacagt ttgacgtaac gcgcgaacgc atccgacaaa
    15241 tcgaggcaaa agcactccgc aagctgcggc atccgacaag aagcgaccgt ttgagaagtt
    15301 tcttggacag cgaagacagc aagctgtaaa ccaaaaaacc gcaggtttca aatacctgcg
    15361 gttttttctt acacaataaa caacgcttcc acatatccca cactcctatc ccgagacctt
    15421 tgcaaaatcc cccaaaatcc cctaaattcc caccaagaca tttaggggat tttccatgag
    15481 caccttcttt cagcaaaccg cccaagccat gattgccaaa cacatcgacc gcttcccact
    15541 attgaagttg gatcaggtaa ttgattggca gccgatcgag cagtacctga accgtcaaaa
    15601 aaaccgttac ctccgagacc accgcggccg tcctgcctat cccctgctgt ccatgttcaa
    15661 agccgtcctg c
//
LOCUS       DAXISH010000051        15304 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.051, whole genome shotgun sequence.
ACCESSION   DAXISH010000051 DAXISH010000000
VERSION     DAXISH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 15304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15304
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.051"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            306..1460
                     /gene="obgE"
                     /locus_tag="ACFOV4_001571"
     CDS             306..1460
                     /gene="obgE"
                     /locus_tag="ACFOV4_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFC7619548.1"
                     /translation="MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGS
                     VWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYGAGADDIVLKMPVGTLIRDLDTG
                     ENVADLTYHGQRVCLAKGGKGGLGNIHFKSSVNRAPKQSTPGEEGEARSLQLELKVLA
                     DVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLI
                     EGAAEGAGLGHRFLKHLSRTGLLLHVVDLAPFDETVNPAEEALAIINELRKYDEELYG
                     KPRWLVLNKLDMLDEEEAQTRTAAFLEAVGWDSPKPDDRFQFDMETPRLFQISALTHQ
                     GTQELVHQINQYLTEKKRIEAEKAEAEQAAAKAEIAEQQPKTDTGVFKPE"
     gene            1543..2592
                     /locus_tag="ACFOV4_001572"
     CDS             1543..2592
                     /locus_tag="ACFOV4_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFC7619549.1"
                     /translation="MSSNQYIQSLELTNFTVLPNDTFEFSENLNVIVAENGCGKTHLL
                     KILYSLLEVTSNTKNRLLKTELQKSFADKLLNVFRPDSLGRLSKRLQGRGRTEIVLKL
                     QNGTTHSSLNFSSNSSSQVNVQSIGLKENEYTPTPIFLPSRELITLCPWFTSLYQNQS
                     IPFEETWFDACMQLNHPLAKGPRETKIRELLEPIENAMGGKVSEEQGRFYLSLTNTGG
                     KIEAPLVAEGLRKFVMIARLIATGALLDKGYLFWDEPEANLNPKLIKVAARIIWSLSQ
                     QGIQVFIATHSLFLLRELELLKLENNTDLPVRFFSLIASDDGTKVEQGNSINDLNTLI
                     LLDENIMQADRYLNI"
     gene            3280..4701
                     /gene="cysS"
                     /locus_tag="ACFOV4_001573"
     CDS             3280..4701
                     /gene="cysS"
                     /locus_tag="ACFOV4_001573"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFC7619550.1"
                     /translation="MTTIYNTLTRQKEPFAPIDPENVRMYVCGMTVYDYCHLGHARVM
                     VVFDMIARWLRECGYPLTYVRNITDIDDKIIARAAENGETIGELTARFIQAMHEDADA
                     LGVLRPDIEPKATENIPQMIAMIETLIQNGKAYPAANGDVYYAVREFAAYGQLSGKSL
                     DDLRAGERVEVDGFKRDPLDFVLWKAAKAGEPAWESPWGRGRPGWHIECSAMSENLFG
                     NTFDIHGGGADLQFPHHENEIAQSVGATGHTCGHHHAQTHHGQSIASHVKYWLHNGFI
                     RVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHYRSPLNYSDAHLDDAKGALTR
                     LYTTLKNTPPADPMPSEAGDDYTRRFYVAMNDDFDTVKAVAVLFELAGEVNKTNNAQL
                     AGRLKALGGIIGLLQRDPTEFLQGGVASDGLSNEEIEDLIARRKQARSDKNWAESDRI
                     RDLLNEHKIILEDNAGGTTWRRG"
     gene            4784..5563
                     /locus_tag="ACFOV4_001574"
     CDS             4784..5563
                     /locus_tag="ACFOV4_001574"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFC7619551.1"
                     /translation="MLKIISANVNGIRSAYKKGFYEYIATSGADIVCVQELKAQEADL
                     SADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFDR
                     LSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLK
                     NWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGW
                     RIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVMEYDYAAE"
     gene            5550..5894
                     /locus_tag="ACFOV4_001575"
     CDS             5550..5894
                     /locus_tag="ACFOV4_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619552.1"
                     /translation="MLPNKVLGKYDWNVDGKTGIGAAWVVAAFILPILVWAIFMLSRM
                     QGWLAPTKANPTWALVWLLICLPCLLIASKCLGWKGWRLLANVLACLAVCALLSVPAA
                     LLIAFTLQDLLK"
     gene            5904..6434
                     /locus_tag="ACFOV4_001576"
     CDS             5904..6434
                     /locus_tag="ACFOV4_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFC7619553.1"
                     /translation="MESFELEDLTLWLVRDADEAEMWIDRWAISYPVVQMSEASAGQS
                     IGEWQAGLQTAFERIRGKYVAVVAHGAGAAAFLAWLYQADILTRKKIANIILVPQRPD
                     IFPDDAEHTFQRVRCPCRAALVVPEHGGVPHGWAQKQADLWNARLLVSPHSGSLNGML
                     GGWQWGMKLMQEMLLA"
     gene            complement(6527..7642)
                     /gene="asd"
                     /locus_tag="ACFOV4_001577"
     CDS             complement(6527..7642)
                     /gene="asd"
                     /locus_tag="ACFOV4_001577"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFC7619554.1"
                     /translation="MKVGFVGWRGMVGSVLMQRMKEENDFAHIPEAFFFTTSNVGGAA
                     PDFGQAAKTLLDANNVAELAKMDIIVTCQGGDYTKSVFQALRDSGWNGYWVDAASSLR
                     MKDDAIIVLDPVNRNVIDNGLKNGVKNYIGGNCTVSLMLMALGGLFQNDLVEWATSMT
                     YQAASGAGAKNMRELISGMGAVHAQVADELADPAGSILDIDRKVSDFLRSEDYPKANF
                     GVPLAGSLIPWIDVDLGNGQSKEEWKGGVETNKILGRSDNPTVIDGLCVRIGSMRCHS
                     QALTLKLKKDLPISEIEAILAGANDWVKVIPNEKEASIRELTPAKVTGTLSVPVGRIR
                     KLGMGGEYISAFTVGDQLLWGAAEPLRRVLRIVLGSL"
     gene            7972..8553
                     /locus_tag="ACFOV4_001578"
     CDS             7972..8553
                     /locus_tag="ACFOV4_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFC7619555.1"
                     /translation="MEEKNDYTDAASDNRNGQEIEVGIAGAGDRILAALLNQLFTFLV
                     LLVPFAGLIAFAIKNEGRIGGSEEIFGLLLGMTSFWVGLAGILVYTVVQIYYMSRDGQ
                     SLGKKIMRIRVLKTDGRNPGFVGTVLVREIAWSVLVAIIAAVIGLAVGDNGENAINLL
                     AFLANFVLLFMVKRDRRTLYDILADTVVVKLPK"
     gene            complement(8615..9469)
                     /gene="folD"
                     /locus_tag="ACFOV4_001579"
     CDS             complement(8615..9469)
                     /gene="folD"
                     /locus_tag="ACFOV4_001579"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HFC7619556.1"
                     /translation="MSAQLINGKEVSQKRLQAVAEAVAQRQQDNLHMPCLAVVLVGGD
                     PASAVYVRNKKTACQKCGIKSLSYELPESTSQEELLALVDRLNADSEVDGILVQLPLP
                     KHLDSQAVLERISPDKDVDGFHPYNVGRLAVKMPLMRPCTPKGVMTLLEAYGIDPKGK
                     KAVVVGASNIVGRPQALELLLARATVTVCHSATENLTDEVAGADILVVGVGIPNFVKG
                     EWIKPGAVVIDVGINRLDDGSLCGDVEFETAKERAAMITPVPGGVGPMTIATLMENTL
                     HAASLHDA"
     gene            9692..9769
                     /locus_tag="ACFOV4_001580"
     tRNA            9692..9769
                     /locus_tag="ACFOV4_001580"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9727..9729,aa:Pro,seq:tgg)
     gene            9794..9870
                     /locus_tag="ACFOV4_001581"
     tRNA            9794..9870
                     /locus_tag="ACFOV4_001581"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9828..9830,aa:Arg,seq:tct)
     gene            9898..9973
                     /locus_tag="ACFOV4_001582"
     tRNA            9898..9973
                     /locus_tag="ACFOV4_001582"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9931..9933,aa:His,seq:gtg)
     gene            10108..10614
                     /locus_tag="ACFOV4_001583"
     CDS             10108..10614
                     /locus_tag="ACFOV4_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HFC7619557.1"
                     /translation="MVDAWSVPDFESKICPPEALAARLALLPRPLVFTNGCFDILHRG
                     HVTYLAQARSAGAALVLALNTDASVRRLGKGGDRPINPLENRAAVAAALESVDLVTWF
                     DEDTPAALIEAVKPEILVKGGDWAADKIVGAAETLVRGGQVFSIPFLHQTSTTKTLAK
                     IRAAEGGK"
     gene            10611..12389
                     /locus_tag="ACFOV4_001584"
     CDS             10611..12389
                     /locus_tag="ACFOV4_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/type III pantothenate kinase"
                     /protein_id="HFC7619558.1"
                     /translation="MTVLKPSHWRVLAELADGLPQHVSQLARMADMKPQQLNGFWQQM
                     PAHIRGLLRQHDGYWRLVRPLAVFDAEGLRELGERSGFQTALKHECASSNDEILELAR
                     IAPDKAHKTICVTHLQSKGRGRQGRKWSHRLGECLMFSFGWVFDRPQYELGSLSPVAA
                     VACRRALSRLGLDVQIKWPNDLVVGRDKLGGILIETVRTGGKTVAVVGIGINFVLPKE
                     VENAASVQSLFQTASRRGNADAAVLLETLLAELDAVLLQYARDGFAPFVAEYQAANRD
                     HGKAVLLLRDGETVFEGTVKGVDGQGVLHLETAEGEQTVVSGEISLRPDDRPVSVPKR
                     RDSERFLLLDGGNSRLKWAWVENGTFATVGSAPYRDLSPLGAEWAEKADGNVRIVGCA
                     VCGEFKKAQVQEQLARKIEWLPSSAQALGIRNHYRHPEEHGSDRWFNALGSRRFSRNA
                     CVVVSCGTAVTVDALTDDGHYLGGTIMPGFHLMKESLAVRTANLNRHAGKRYPFPTTT
                     GNAVASGMMDAVCGSVMMMHGRLKEKTGAGKPVDVIITGGGAAKVAEALPPAFLAENT
                     VRVADNLVIHGLLNLIAAEGGESEHT"
     gene            12502..13326
                     /locus_tag="ACFOV4_001585"
     CDS             12502..13326
                     /locus_tag="ACFOV4_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HFC7619559.1"
                     /translation="MKWLFTLLAVLNIAVFGGTVGYKLAVKATGGVPENRAVENTPPA
                     TPAADNAAASVEDTAALLKPGDILTEEQAEQLRLKKEAEQKKLREKKQREEKARREKL
                     AAEKAQAERENGAADALCAAQASLTMDEDDYHRIKGLLGKWSHVASRSVEKRTAQAKP
                     ADKTYRVVLPVSADAENQAAELSAKGFNPIPFDGALSLGVGNSRENAQALQNRLAGAG
                     FGGAHIVEHFAEADRQDDSLSVSRMTVLFTGVNAADAEEIRKITSLYGKLNLKSCK"
     gene            complement(14089..14877)
                     /locus_tag="ACFOV4_001586"
     CDS             complement(14089..14877)
                     /locus_tag="ACFOV4_001586"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HFC7619560.1"
                     /translation="MLTLYGETFPSRLLLGTAAYPTPEILKQSVRTARPAMITVSLRR
                     AGSGGEAHGQGFWSLLQETGVPVLPNTAGCQSVQEAVTTAQMAREVFETDWIKLELIG
                     DDDTLQPDVFQLVEAAEILIKDGFKVLPYCTEDLIACRRLLDAGCQALMPWAAPIGTG
                     LGAVHAYALNVLRERLPYTPLIIDAGLGLPSQAAQVMEWGFDGVLLNTAVSRSGDPVN
                     MARAFALAVESGRLAFEAGPVEARDKAQASTPTVGQPFWHSAEY"
     gene            complement(15091..15285)
                     /gene="thiS"
                     /locus_tag="ACFOV4_001587"
     CDS             complement(15091..15285)
                     /gene="thiS"
                     /locus_tag="ACFOV4_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HFC7619561.1"
                     /translation="MNIILNGGPAELHGTSVADLIAQTAPQQPFAVAVNTVFIPKGAY
                     AETVLNENDKIDIVRPVVGG"
BASE COUNT         3654 a         3866 c         4254 g         3530 t
ORIGIN      
        1 cgagtttatc ctagttatct aggacagccc caaaacttat tatatgtaac ggtttgaacg
       61 gacattccgt cgggtcggaa tgtcaaaaag gcgcgattgt accaaagaag ttggacataa
      121 ttttgtttgc aggctgaaga tttgcttaaa aattcattaa gatgggcgga acaaatagtt
      181 tgggtacggc gtgttgaaat accgcttatc ccttataata gcgtccgaaa ttctgttcag
      241 acggcatcaa aacacacggt aatccgtctg aacccccatt tgaaaccaac aaacaagagc
      301 attgaatgaa attcatcgac gaagcaaaaa tcgaagtcgc cgcaggcaaa ggcggtaatg
      361 gcgcaaccag tttccgccgc gaaaaattcg taccgcgcgg cggtccggac ggcggcgacg
      421 gcggcaaagg cggcagcgtt tgggcagaag ccgacgaaaa caccaacacc ctcgtcgaat
      481 accgcttcgt taaacgctac caagccaaaa acggcgaaaa aggccacggt tccgaccgtt
      541 acggcgcagg tgcggacgac atcgtcctca aaatgcccgt cggcaccctt atccgcgacc
      601 tcgacaccgg cgaaaacgtt gccgacctca cttatcacgg acagcgcgtc tgccttgcca
      661 aaggcggcaa aggcggcttg ggcaacatcc acttcaaatc ctccgtcaac cgcgccccaa
      721 aacaatccac gcccggcgaa gaaggcgaag cccgttccct gcaactcgaa ctcaaagtcc
      781 tcgccgatgt cggcttattg ggtatgccca acgccggcaa atccaccctg attaccgccg
      841 tatccgccgc acgccccaaa atcgccaact accccttcac caccctgcat ccaaacttag
      901 gcgtggtacg catcgacgaa aaccacagct tcgtgatggc cgacatcccc ggcctgattg
      961 aaggcgcggc agaaggcgcg ggtttggggc atcgtttcct caaacactta tcgcgcaccg
     1021 gattattgct gcacgtcgtc gatttggcgc ccttcgacga aaccgtcaac ccggccgaag
     1081 aagcacttgc catcatcaac gaattgcgca aatacgatga agaactttac ggcaaaccgc
     1141 gctggctggt gctgaataaa ctcgacatgc ttgacgaaga agaagcccaa acgcgcactg
     1201 ccgccttcct cgaagccgtc ggctgggact cccccaaacc cgacgaccgt ttccaatttg
     1261 acatggaaac cccgcgcctc ttccaaatca gcgcgctgac ccaccaaggc acgcaggaat
     1321 tggtacacca aatcaaccaa tacctgaccg agaaaaaacg tatcgaagcc gaaaaagcag
     1381 aagcggaaca ggcagcggca aaagccgaaa ttgccgagca gcagccgaaa acggatacgg
     1441 gcgtgtttaa gccggagtga aaaaagaaag ggtttcagac gatatttgtt ctacaaaagg
     1501 ttgtttgaaa caattttaaa gcaagattga aatggattaa aaatgtcatc taaccaatat
     1561 atccagtcgc ttgagttgac aaactttacc gttcttccaa acgatacttt tgaattttct
     1621 gaaaatctca atgttattgt tgccgaaaac ggttgtggca aaacacattt gttaaaaatt
     1681 ttatacagcc tgctagaagt aacatctaac accaaaaaca gattactgaa aacagaattg
     1741 caaaaaagtt ttgccgataa attactgaat gttttccgtc ccgattcctt gggcaggttg
     1801 agcaaacgtt tgcaggggcg cgggcgtacg gaaatcgttt taaaactgca aaacggcact
     1861 acgcatagta gtctgaattt ttccagtaac tcatcatcgc aagtcaatgt tcaaagcatc
     1921 ggattgaaag aaaatgaata tactccgaca cctatcttct tacccagccg cgaattaatt
     1981 acactttgcc cttggttcac ttctttgtat caaaaccaaa gcatcccttt cgaagaaact
     2041 tggtttgatg cctgtatgca attaaatcac ccgcttgcca aaggccccag agaaacaaaa
     2101 attcgagaat tgctcgaacc tattgagaac gcgatgggcg gaaaagtatc tgaagaacaa
     2161 ggaaggtttt atctatcgct gacaaatacg ggcggtaaga ttgaagcacc tttggtagca
     2221 gagggtttgc ggaaatttgt catgattgcc cggttaatcg caacaggggc attgctggat
     2281 aaaggctatc tattttggga tgaaccggaa gctaatctga atcctaaatt gatcaaagtg
     2341 gctgcccgta ttatttggtc tttatctcaa cagggtattc aggtttttat tgcaacacac
     2401 tctttattct tattgagaga attggaactt ttgaagcttg aaaataacac ggatttacct
     2461 gtacgttttt tctcgttgat tgcttccgat gatggaacaa aagtggagca agggaacagt
     2521 attaatgatt tgaacacatt gatattgtta gatgaaaaca ttatgcaggc agacaggtat
     2581 ctgaatattt gaggttaagc tatgactaca atcacagaaa agagattaac ctttgctttt
     2641 cctgaagatt attacgttac caagtatgac gaatgggaac attataaaat ttttcagaac
     2701 agttgtaatt tacgtaataa aattgataca aatgaaaagg gaaagaacgg gataaatcaa
     2761 agtgtagatg acgataatgg cagctcaggt gtagatataa tagcccttca tgaatcgaca
     2821 ctttggctaa tcgaaattaa agattattac cgacttgggc ttgagccaaa tgcccaatca
     2881 atagatgaaa aactttctga cctaccatat ttaatcgcaa gaaaaattcg agattcattg
     2941 gcaggattgg tttctgctaa atttaaagca gaaaaacagg aagaaaaaga tttttctcgc
     3001 ttggctttag attgtaacga aataaaaata gtccttcata ttgaaatgcc tagtataaga
     3061 agtaaacttt atccctcgtc atcagattta gcaaacttat taaaagataa gtttaaatta
     3121 tcagaattta caaaaaattt tgcaaactgt tatgcagaac caattttcac aaatatcagc
     3181 catattaata atccgcaact acgtaatgtt ccttggtccg tatctacagg aacagaacag
     3241 aaattatcat ccgagcaaca aagattaatc catagtccca tgaccaccat ctacaacacc
     3301 cttacccgcc aaaaagaacc ctttgccccc atcgaccctg aaaacgtgcg tatgtacgtt
     3361 tgcggcatga ctgtttacga ctattgccac ttaggccatg cccgtgtgat ggtggtgttt
     3421 gacatgattg cccgttggtt gcgcgagtgc ggctatccgc tcacttatgt acgcaacatc
     3481 accgacatcg acgacaaaat cattgcccgt gcggctgaaa acggcgagac catcggcgag
     3541 ctgactgcgc gtttcattca ggctatgcac gaagatgccg atgctttggg cgtgttgcgt
     3601 cccgatatcg agccgaaggc gacggaaaac attccgcaaa tgattgcgat gattgaaacc
     3661 ctgattcaaa acggcaaggc ttatcctgcc gccaacggcg acgtttacta cgccgtgcgc
     3721 gagtttgccg cttacggcca attatcgggc aaatcgttag acgacctgcg tgcaggtgag
     3781 cgtgtggaag tggacggttt caaacgcgat ccgcttgatt ttgtgttgtg gaaagcggcg
     3841 aaagcaggcg aaccggcgtg ggaaagccct tggggcaggg gacggccggg ctggcacatt
     3901 gaatgctccg ccatgagtga aaacctgttc ggcaatacct tcgacatcca cggcggcggc
     3961 gcggatttgc agtttccgca ccacgaaaac gaaattgccc aaagcgtcgg cgcgacgggg
     4021 catacctgcg gtcatcatca cgcgcaaacc caccacgggc aaagcatcgc cagccacgtc
     4081 aaatattggc tgcacaacgg ctttatccgc gtggacggcg aaaaaatgtc caaatcactg
     4141 ggcaacttct tcaccatccg cgaagtgttg aaacaatacg accccgaagt cgtgcgcttc
     4201 ttcatcctgc gcgcccacta ccgcagcccg ttgaactatt ccgacgcgca tttggacgac
     4261 gcaaaaggcg cgttgacgcg tttgtatacg actttgaaaa atacgccgcc cgccgatccg
     4321 atgccgtctg aagccggcga tgactacacg cgccgctttt atgttgcgat gaatgatgat
     4381 tttgatacgg tgaaagcggt ggcggtgttg ttcgaacttg ccggcgaagt gaacaaaacc
     4441 aataacgcgc aactggcagg ccgtctgaag gctttgggcg gcatcatcgg actgctgcaa
     4501 cgcgatccga ccgagttcct gcaaggcggc gtggcttcag acggtctctc caacgaagaa
     4561 atcgaagact tgatcgcccg ccgcaaacag gcgcgctccg ataaaaactg ggcggaatcc
     4621 gaccgcatcc gcgaccttct gaacgaacac aaaatcattt tggaagacaa cgccggcggc
     4681 acgacttggc ggcgcggtta aaatccatcg aaaagggtaa atgtgccgca ttttgccctt
     4741 ttttgttcag acggcatttt tattgtgaga acttattttt attatgctta aaatcatttc
     4801 cgccaacgtc aacggcatcc gctccgccta caaaaaaggt ttttacgaat acatcgccac
     4861 atcgggcgcg gacattgtct gcgtgcagga actcaaagcg caggaggctg atttgtctgc
     4921 cgatatgaaa aatccgcacg ggatgcacgg ccattggcat tgcgccgaga agcgcggtta
     4981 cagcggcgtg gcggtgtaca gcaaacgcaa acccgacaat gtgcaaatcg gtatgggcat
     5041 tgaagaattc gacagggaag ggcggtttgt gcgttgcgat ttcgacaggt tgagcgttat
     5101 ttcgctttac ttgcccagcg gcagcagcgc ggaagaacgc cagcaggtga aataccgttt
     5161 ccttgatgcg ttttacccta tgctcgaagc gatgaaaaac gaaggacgcg acattgtcgt
     5221 ttgcggcgac tggaacatcg cccaccaaaa catcgacctg aaaaactgga aaggcaatca
     5281 gaaaaattcg ggcttcctac cggaagaacg cgagtggata ggcaaggtta tccacaagct
     5341 cggttggacg gatatgtggc gcacgcttta tcccgatgtg ccgggctaca cgtggtggag
     5401 caaccgcggg caggcgtatg cgaaagatgt cgggtggcgc atcgattatc agatggttac
     5461 gcccgaactt gccgccaaag ccgtgtccgc acacgtttat aaagatgaaa aattttccga
     5521 ccatgcgccg ctggtcatgg agtatgacta tgctgccgaa taaagttttg ggtaaatatg
     5581 attggaatgt ggacggaaaa acaggaatag gcgcagcatg ggttgtcgct gcgtttatcc
     5641 tgcccatatt ggtgtgggcg atatttatgt tgtcgcggat gcaaggctgg cttgcgccga
     5701 ccaaggcaaa cccgacatgg gcgttggtgt ggctgctgat ctgcctgccc tgcctgctga
     5761 ttgcgtccaa atgtttgggt tggaaaggct ggcggctgtt ggcaaacgtt cttgcctgcc
     5821 tcgccgtgtg cgctctgttg agtgtgcctg ccgcgctgct gattgcgttc acgctgcaag
     5881 acctgctcaa ataggcgcgg acaatggaaa gtttcgagct tgaggatttg acgctgtggc
     5941 tggtacgcga tgcggatgaa gcggaaatgt ggatagaccg ctgggcgatc agttatcccg
     6001 tcgtgcagat gtccgaagcg tcggccggtc aaagcatagg ggaatggcag gcagggcttc
     6061 agacggcatt tgaacgcata cgcggcaaat acgtcgccgt tgtcgcacac ggtgcgggcg
     6121 cggccgcatt tttggcgtgg ctgtatcagg cagacatcct gacacggaag aaaattgcca
     6181 acatcatcct tgtaccgcag cgtcccgata tttttcccga cgatgcggaa cacactttcc
     6241 aacgcgtccg ctgtccctgc cgtgccgcat tggttgtacc cgaacacggc ggcgtgccgc
     6301 acggttgggc gcaaaaacag gcggatttgt ggaacgcccg cctgttggtt tccccgcatt
     6361 cgggcagttt gaacggcatg ctcggcggct ggcagtgggg tatgaagctg atgcaggaaa
     6421 tgttgctggc gtgaacgctt gccttatcgg aatttcggtt aactggggtt gcaaggaaaa
     6481 tgccgtctga aacaggcttc agacggcatt tccattcaaa cagggcttac aggctgccca
     6541 acacgatacg caatacgcgg cgcagcggct cggccgcgcc ccacaagagc tggtcgccga
     6601 cggtgaacgc gctgatgtat tcgccgccca tacccagttt gcggatgcgt ccgacgggga
     6661 cggacagcgt gccggtaact ttggcggggg tcagctcgcg gatgctggct tctttttcgt
     6721 tggggatgac tttcacccag tcgttcgcgc ctgccaaaat cgcttcgatt tcggaaatgg
     6781 gcaggtcttt tttcaacttc agggtaaggg cttggctgtg gcagcgcata gagccgatgc
     6841 ggacgcacag gccgtcaatc acggttggat tgtcgctgcg gccgaggatt ttgttggttt
     6901 ccacgccgcc tttccattct tctttggact ggccgttgcc caaatccacg tcaatccacg
     6961 gaatcaggct gccggcgagc ggtacgccga agttggcttt cggatagtct tcgctgcgca
     7021 ggaaatcgga tactttgcgg tcgatgtcga gaatcgagcc ggcaggatcg gcaagttcgt
     7081 ccgccacttg ggcgtgaacc gcgcccatac cgctgatgag ttcgcgcatg tttttcgcac
     7141 ctgcgccgga agcggcttgg taggtcatgc tggttgccca ttcgaccaaa tcgttttgga
     7201 acaggccgcc caaagccatc agcatcaggg agacggtgca gttgccgccg atgtagtttt
     7261 tcacgccgtt tttgaggccg ttgtcgataa cgttgcggtt gacagggtcg aggacgataa
     7321 tcgcgtcgtc tttcatgcgc agagaagatg ccgcgtcaac ccagtagccg ttccagccgc
     7381 tgtcgcgcag ggcttggaag acggatttgg tgtaatcgcc gccttggcag gtaacgatga
     7441 tgtccatttt ggcgagttcg gcaacattgt tggcatctaa taatgtttta gccgcctgac
     7501 cgaaatcagg ggctgcgccg ccgacgttgg aagtggtaaa gaaaaacgct tcaggaatgt
     7561 gggcgaagtc gttttcttct ttcatacgct gcatcaaaac cgaaccgacc ataccgcgcc
     7621 agccgacgaa acctactttc attgtgttgc tccttgagga aaaaatcgtt aatatagcgg
     7681 attaacaaaa accagtacgg cgttgcctcg ccttagctca aagagaacga ttctctaagg
     7741 tgctgaagca ccaagtgaat cggttccgta ctatttgtac tgtctgcggc ttcgtcgcct
     7801 tgtcctgatt tttgttaatc cactataaaa ttatgtatgg cgtaaaggaa gcgttttaac
     7861 gccgtattgg gaaaatgtaa agttctttat cgggatttct ttaagtattg gcgttttcgg
     7921 tgtcgtggcg gtagaatcgg ggtcagttaa gaacaattat caggaacgga tatggaagaa
     7981 aaaaacgact acaccgacgc ggcatccgac aaccgcaacg ggcaggaaat tgaagtcgga
     8041 attgccggcg caggcgaccg gatacttgcc gcgctgctga accaattgtt tacctttttg
     8101 gttttgttgg tgccgtttgc cggactgatt gctttcgcca tcaagaatga aggcaggatt
     8161 ggcggcagtg aggaaatatt cgggctgctt ttgggcatga cttccttttg ggtaggactg
     8221 gcgggcattt tggtttatac cgtcgttcaa atctactata tgagcaggga cgggcagtca
     8281 ttgggtaaga agatcatgag aatcagggtg ttgaaaaccg acggccgcaa tccgggtttt
     8341 gtcggcacgg ttttggtacg cgaaatcgca tggtcggttt tggttgccat tattgccgcc
     8401 gttatcggtc ttgcagtagg tgacaacgga gaaaacgcca tcaacctgct ggcattcctt
     8461 gccaactttg tcctgctctt tatggtcaaa cgcgaccgcc gcacgcttta cgacatactg
     8521 gcggatacgg ttgtcgtcaa gctgcccaaa taaacggaca cggcaaaatg ccgtctgaaa
     8581 gcctttcaga cggcattttt atcttcagaa ccgcttaagc atcgtgcagc gaagccgcgt
     8641 gcaaagtgtt ttccattaat gtggcaatcg tcatcggacc cacgccgccg ggaacgggcg
     8701 taatcatcgc cgcccgttct tttgccgttt caaattccac gtcgccgcac aggctgccat
     8761 cgtccaaacg gttgatgccc acatcaataa cgaccgcgcc aggtttgatc cattcgcctt
     8821 tgacaaagtt cggaatgcct acgccgacca ccaaaatatc ggctccggca acctcgtctg
     8881 tcagattttc ggttgcgctg tggcagaccg ttaccgttgc gcgcgccagc agcagttcca
     8941 aagcctgcgg gcggccgacg atattcgacg cgccgaccac gaccgctttt ttccccttcg
     9001 gatcaatgcc gtaagcttcc aaaagcgtca tcacgccctt gggcgtacac gggcgcatca
     9061 gcggcatttt gaccgccagc ctgccgacat tgtaaggatg gaagccgtcc acgtccttat
     9121 ccggcgaaat acgttccaaa accgcctggc tgtcgaggtg cttcggcagc ggtagctgaa
     9181 ccagaatacc gtccacttcg gaatcggcat tcaggcggtc gaccagtgcc agcagttctt
     9241 cctgcgatgt tgattcgggc agctcgtaag acagtgattt gatgccgcat ttttggcagg
     9301 cggttttctt gttgcggaca taaaccgcgc tggcagggtc gcctccgacc aaaaccacgg
     9361 ccaggcaagg catgtgcaga ttgtcctgtt ggcgttgcgc caccgcttcg gcaaccgcct
     9421 gcaggcgttt ttgcgaaact tctttaccat tgatcagttg tgccgacata tccgtccttt
     9481 tgttaaacag gtagaaaatg ctgaaaatta tcgcattttc cgtttgtttt tacagcagga
     9541 tgccgaaaat aaatttgccc tgaaataaaa tacggctgtt tggacggatt aaatattttt
     9601 tcaaatcaaa aaactatatt tttcatcttg gtgtcttgaa aataaatatt gacgcatctt
     9661 tccctgagtt gtatagttcg cttcttcaag tcggggcgta gcgcagcccg gttagcgcat
     9721 ctgctttggg agcagagggt cgtgagttcg aatcccaccg ccccgaccaa tcaatcagca
     9781 cgaatcggca tgagcgcccg tagctcaacc ggatagagca ccgaccttct aagtcggggg
     9841 ttacaggttc gattcctgtc gggcgtgcca agaatttgat tgaaaaccgt ttttatggtg
     9901 gctgtagctc agttggtaga gccccggatt gtgattccgg ttgtcgtggg ttcgagcccc
     9961 atcagccacc ccagataaag gcccgtactt ttcggtacgg gtcttttccc gtttgcgcgt
    10021 actgtccgcg ccgccggctt tgcctttcgc atatgcttct gtatcatgta ggttttctgt
    10081 cttttatggt ttttgtcgga gactttgatg gttgacgctt ggtctgttcc tgattttgaa
    10141 tcgaaaatct gtccgcccga ggcgttggcg gcgcgtttgg cgttgttgcc gcgcccgctg
    10201 gtgtttacca acggctgttt cgacatcctc cacagggggc acgttactta tctggcgcag
    10261 gcgcgttcgg caggggcggc gttggtgctg gcgttgaata ccgatgcttc ggtgcggcgt
    10321 ttgggcaagg gcggcgaccg cccgattaat cctttggaga accgtgccgc cgttgccgcc
    10381 gcgttggaaa gtgtggattt ggtaacgtgg tttgacgagg atacgccggc ggcgttgatc
    10441 gaggcggtca aacctgagat tttggtcaag ggcggcgatt gggctgcgga taagattgtc
    10501 ggcgcggcgg aaacgttggt gcgcggcggt caggtgtttt caattccgtt tctgcaccag
    10561 acttcgacaa cgaagacttt ggcaaaaatc cgtgcggcag agggcggaaa atgacggttt
    10621 tgaagccttc gcactggcgg gtgttggcgg agcttgccga cggtttgccg caacacgtct
    10681 cgcaactggc gcgtatggcg gatatgaagc cgcagcagct caacggtttt tggcagcaga
    10741 tgccggcgca catacgcggg ctgttgcgcc aacacgacgg ctattggcgg ctggtgcgcc
    10801 cattggcggt tttcgatgcc gaaggtttgc gcgagctggg ggaaaggtcg ggttttcaga
    10861 cggcattgaa gcacgagtgc gcgtccagca acgacgagat actggaattg gcgcggattg
    10921 cgccggacaa ggcgcacaaa accatatgtg tgacccacct gcaaagtaag ggcagggggc
    10981 ggcaggggcg gaagtggtcg caccgtttgg gcgagtgtct gatgttcagt tttggctggg
    11041 tgtttgaccg gccgcaatat gagctgggtt cgctgtcgcc tgttgcggca gtggcgtgtc
    11101 ggcgcgcctt gtcgcgttta ggtttggatg tgcagattaa gtggcccaat gatttggttg
    11161 tcggacgcga caaattgggc ggcattctga ttgaaacggt caggacgggc ggcaaaacgg
    11221 ttgccgtggt cggtatcggc atcaatttcg tgctgcccaa ggaagtagaa aatgccgctt
    11281 ccgtgcaatc gctgtttcag acggcatcgc ggcggggaaa tgccgatgcc gccgtgttgc
    11341 tggaaacgct gttggcggaa cttgatgcgg tgttgttgca atatgcgcgg gacggatttg
    11401 cgccttttgt ggcggaatat caggctgcca accgcgacca cggcaaggcg gtattgctgt
    11461 tgcgcgacgg cgaaaccgtg ttcgaaggca cggttaaagg cgtggacgga caaggcgttc
    11521 tgcacttgga aacggcagag ggcgaacaga cggtcgtcag cggcgaaatc agcctgcggc
    11581 ccgacgacag gccggtttcc gtgccgaagc ggcgggattc ggaacgtttt ctgctgttgg
    11641 acggcggcaa cagccggctc aagtgggcgt gggtggaaaa cggcacgttc gcaaccgtcg
    11701 gtagcgcgcc gtaccgcgat ttgtcgcctt tgggcgcgga gtgggcggaa aaggcggatg
    11761 gaaatgtccg catcgtcggt tgcgctgtgt gcggagaatt caaaaaggca caagtgcagg
    11821 aacagctcgc ccgaaaaatc gagtggctgc cgtcttcggc acaggctttg ggcatacgca
    11881 accactaccg ccaccccgaa gaacacggtt ccgaccgctg gttcaacgcc ttgggcagcc
    11941 gccgcttcag ccgcaacgcc tgcgtcgtcg tcagttgcgg cacggcggta acggttgacg
    12001 cgctcaccga tgacggacat tatctcgggg gaaccatcat gcccggtttc cacctgatga
    12061 aagaatcgct cgccgtccga accgccaacc tcaaccggca cgccggtaag cgttatcctt
    12121 tcccgaccac aacgggcaat gccgtcgcca gcggcatgat ggatgcggtt tgcggctcgg
    12181 ttatgatgat gcacgggcgt ttgaaagaaa aaaccggggc gggcaagcct gtcgatgtca
    12241 tcattaccgg cggcggcgcg gcaaaagttg ccgaagccct gccgcctgca tttttggcgg
    12301 aaaataccgt gcgcgtggcg gacaacctcg tcattcacgg gctgctgaac ctgattgccg
    12361 ccgaaggcgg ggaatcggaa catacttaaa aaatacaccc tttttcaaca cggggcggta
    12421 tccgtccgaa tccgtccgga ttctgccgcc cgacagactg ccgcccaggc gggcggggtt
    12481 tcaaacattg aggaaattct aatgaaatgg ctcttcaccc ttttggcggt actcaatatt
    12541 gccgtattcg gcggcacggt gggctataaa ttggccgtta aagcgacggg cggcgtgccg
    12601 gaaaaccggg ccgtcgaaaa cacgcccccc gcaacgcccg ccgccgacaa tgcggcggca
    12661 tccgtggagg atacggcggc actgctcaaa ccgggcgaca tcctgaccga agagcaggcg
    12721 gagcagttgc gcttgaagaa agaagcggaa cagaaaaaac tgagggagaa aaaacagcgt
    12781 gaagaaaaag cccgccgcga aaaactcgcc gccgaaaagg cgcaggcgga acgcgaaaac
    12841 ggcgcggcgg atgccttatg cgccgcgcag gcaagcctca cgatggacga agatgactac
    12901 caccgcatca aaggactttt gggcaaatgg tcgcacgttg ccagcaggag cgtcgaaaaa
    12961 cgcaccgccc aagccaaacc tgccgacaaa acctaccgcg tcgtcctgcc cgtttccgcc
    13021 gatgccgaaa atcaggcggc ggagctgtct gccaaaggtt tcaaccccat accgtttgac
    13081 ggcgcattga gtttgggtgt cggcaacagc cgggaaaacg cccaagccct gcaaaaccgg
    13141 cttgccggcg ccggattcgg cggggcgcat attgtcgaac actttgccga agccgacagg
    13201 caggacgatt ctttgagcgt gtcgcgtatg acggttttgt ttaccggcgt gaatgccgcc
    13261 gatgcggaag aaattcgtaa aatcacgtcc ctatacggca aactgaacct caagtcttgc
    13321 aaataggcgc gaaagccgga cgataaacgc caaacccacc gcgaaggtgg gtttggcgtt
    13381 tcggttttga gtatctgata tataaaaagg gaatgtatgt ctcgtatatg ccgactccaa
    13441 gtgtgaaagt gatgatgggg aaatatggtg tttaatggtt cggaacggac ggcttccgag
    13501 tggttttgat tatacgctaa taataataat tatcaataaa aatttaaaaa taaatgcaga
    13561 ttttttgtaa tacgatgaaa aataaacaaa ttaacctgtc cgccgatgtt tgtgattcgg
    13621 gtcggcaaac tttcattgtg tcggacaaat cggggtcggc agtcatagct gagggcttcg
    13681 tgcctgacgg aaataaggtt gcccgtgttt gaacatccgt ccgattgggc gcggacaggg
    13741 ttgtcattcg ggggtgtttg agcgtggatt cggggatgcg aaagcggtaa aaccgttgcg
    13801 gatgaaggct tacggacggc tttaggtatt tttaagtgta ttcaaacaac aacaaaacgc
    13861 ttcttctatt gccgtattta gggcttgcgc ggcagcctgc acaccgtgga ggccgagtgt
    13921 ttcgttggtt gcggcatcgg gacgggcggc aaggttttcc ggccggtttt tccatttttt
    13981 ccgacaaagc cgtgatgccg gggaatggcg gtttgtccgt ttcggaccgc cgccgttttg
    14041 agccgcgatg ccgtctgaag ccttcagacg gcatttttgc cgcctttttc aatattccgc
    14101 cgaatgccaa aacggctgtc cgactgtcgg cgtgctggct tgcgctttgt cgcgtgcttc
    14161 gaccggtccg gcttcaaatg ccagccgtcc ggattcgacg gcgagtgcga aggcgcgtgc
    14221 catattgact ggatcgccgc tgcgggaaac ggcggtgttc aaaagcacgc cgtcaaagcc
    14281 ccattccatc acttgtgccg cctgtgaggg caaacccaag cccgcgtcga taatcagcgg
    14341 cgtgtagggc aggcgttcgc gcaggacgtt caacgcgtag gcgtgaaccg cgcccaaacc
    14401 cgtgccgatc ggggccgccc acggcatcaa cgcctgacag cccgcgtcga gcaggcggcg
    14461 gcaggcaatc aggtcttcgg tgcaataagg cagcactttg aagccgtctt taatcaggat
    14521 ttccgccgct tcgacaagct ggaacacatc cggctgcaag gtgtcgtcat ctccgatgag
    14581 ttccaatttt atccaatcgg tttcaaacac ttcgcgcgcc atttgcgccg tcgttaccgc
    14641 ttcctgcacg ctttggcagc ctgccgtgtt cggcaggacg ggaacgccgg tttcttgaag
    14701 cagcgaccaa aacccctgac cgtgtgcctc cccaccgctt cccgcgcggc gcagcgagac
    14761 ggtaatcatc gcaggccggg cggttcggac ggattgtttg aggatttcag gggtcgggta
    14821 ggcagccgtg ccgagcagca gccgtgaagg gaaagtttct ccgtataggg tgagcataat
    14881 gggttccttt gtatagtgga ttaacaaaaa ccagtacggc gttgcctcgc cttagctcaa
    14941 agagaacgat tctctaaggt gctgaagcac caagtgaatc ggttccgtac tatttgtact
    15001 gtctgcggct tcgtcgcctt gtcctgattt aaagttaatc caccataacg ttgttttggg
    15061 gacaggggtc gtctgaaaag gcaaaaccgc ctagccgccg acgacggggc ggacgatatc
    15121 gattttgtcg ttttcgttca aaaccgtttc cgcatacgcg cctttgggga tgaaaacggt
    15181 gttgaccgcc acggcaaagg gctgttgcgg cgcggtttgg gcgatgaggt cggcaacgct
    15241 tgtgccgtga agttcggcgg gtccgccgtt taagatgatg ttcatggttt ctcgatgttt
    15301 ctgt
//
LOCUS       DAXISH010000052        15198 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.052, whole genome shotgun sequence.
ACCESSION   DAXISH010000052 DAXISH010000000
VERSION     DAXISH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 15198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15198
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.052"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(85..477)
                     /gene="rpsI"
                     /locus_tag="ACFOV4_001588"
     CDS             complement(85..477)
                     /gene="rpsI"
                     /locus_tag="ACFOV4_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019958115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFC7619562.1"
                     /translation="MNGKYYYGTGRRKSSVARVFLIKGTGQIIVNGRPVDEFFARETS
                     RMVVRQPLVLTENAESFDIKVNVVGGGETGQSGAIRHGITRALIDFDAALKPALSQAG
                     FVTRDAREVERKKPGLRKARRAKQFSKR"
     gene            complement(487..918)
                     /gene="rplM"
                     /locus_tag="ACFOV4_001589"
     CDS             complement(487..918)
                     /gene="rplM"
                     /locus_tag="ACFOV4_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFC7619563.1"
                     /translation="MKTFSAKPHEVKREWFVIDAQDKVLGRVAAEVASRLRGKHKPEY
                     TPHVDTGDYIIVINADKLRVTGAKFEDKKYFRHSGFPGGIYERTFREMQEQFPGRALE
                     QAVKGMLPKGPLGYAMIKKLKVYAGAEHAHAAQQPKVLELK"
     gene            complement(1096..1275)
                     /gene="ssrS"
                     /locus_tag="ACFOV4_001590"
     ncRNA           complement(1096..1275)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACFOV4_001590"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(1281..1586)
                     /locus_tag="ACFOV4_001591"
     CDS             complement(1281..1586)
                     /locus_tag="ACFOV4_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFC7619564.1"
                     /translation="MNIEQVHIEVMHARLTVNTPAEEKDTLLQAVGMLNGKAEAIREG
                     GRVADSEKIVIMATLNVVHDLLKTSLNGGDLAIGDFARKIADMDNACQKALSRLAQE"
     gene            complement(1597..1926)
                     /locus_tag="ACFOV4_001592"
     CDS             complement(1597..1926)
                     /locus_tag="ACFOV4_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619565.1"
                     /translation="MKQNIEKLESSVYTLVQKFETLVSENRRLKETVAELKRAHERQK
                     LEHETAVDELSEALLVQVGKLKEDLQNKIDSLTEENTRYRSLLEQSREKISALAARLP
                     QWQETQQ"
     gene            complement(1981..2970)
                     /locus_tag="ACFOV4_001593"
     CDS             complement(1981..2970)
                     /locus_tag="ACFOV4_001593"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046167 - glycerol-3-phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFC7619566.1"
                     /translation="MKITVIGAGSWGTALALHFSQHGNRVSLWTRNADQVRQMQEARE
                     NKRGLPGFSFPETLEVCADLADALKDSGLVLIVTSVAGLRSSAELLKQYGAGHLPVLA
                     ACKGFEQDTGLLTFQVLKEVLPDNKKIGVLSGPSFAQELAKQLPCAVVLASENQEWIE
                     ELVPQLNTTVMRLYGSTDVIGVAVGGAVKNVMAIATGLSDGLEYGLNARAALVTRGLA
                     EITRLASAMGAQPKTMMGLAGIGDLILTCTGALSRNRRVGLGLAEGKELHQVLVEIGH
                     VSEGVSTIEEVFNTACKYQIDMPITQTLLQLIRKEMTPQQVVERLMERSARFE"
     gene            complement(3093..5795)
                     /gene="ppc"
                     /locus_tag="ACFOV4_001594"
     CDS             complement(3093..5795)
                     /gene="ppc"
                     /locus_tag="ACFOV4_001594"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HFC7619567.1"
                     /translation="MQLHILNNPKDAALAADAEFLKQSLFNLLHEEASPLVVETVKLL
                     STSDDSAALIEKVLPQLDEQQTHDLTLACGLFAQILNIAEDVHHERRRQIHEEAGRGG
                     AEGSLTETVRRLKAGKADGKSVQRQLDNTSVTAVLTAHPTEVQRQTVLSFNRRIRALL
                     PQRERCTNADALARLRREIDTILLGLWQTSETRRHKLSVNDEINNGVSIFPMSFFEAL
                     PKLYRKMEHDFQMVYPDVCVPNILKIGGWIGGDRDGNPFVSAETLRFAFRRHADAVFR
                     FYRGELDKLYRELPLSIRRVKVNDDVMALAALSPDEEIARTEEPYRRAIAYIMARAMG
                     KARSLGLGMGCKFGFLEPYASAQEFLDDLKKLQRSLIDNGSRLLAEGRLADLIRSVSV
                     FGFHMMPLDLRQHAGKHADVVTELFQHAGLEDYNSLNEEQKQAVLLRELSHQRPLYSP
                     FITYSDHTRHELAIFNEARKIKDEFGEDAVTQSIISNCEQPSDLLALALLLKESGLLA
                     VENGKPRSRINIVPLFETIEALENACPVMETMFRLDWYDALLESRGNIQEIMLGYSDS
                     NKDGGYVTSSWCLYQAELGLVELFKKYDVRMRLFHGRGGSVGRGGGPSYQAILAQPAG
                     SVAGQIRITEQGEVITAKYADPGNAQRNLETLVAATLEASILPDKKDPDAKLMQALSD
                     VSFKYYRELITHPDFIDYFLQTSPIQEIATLNLGSRPASRKTLARIQDLRAIPWVFSW
                     MQNRLMLPAWYGFGSAVETLCEDKPETLAALREHAQSNPFFQAMLSNMEQVMAKTDIT
                     LAENYAGLSESPDKAKVIFGMIKEEYQRSRKALLDLLQTEELLRDNRSLARSLALRIP
                     YLNALNGLQVAMLKRLRKEPDNPHALLMVHLTINGVAQGLRNTG"
     gene            5838..6731
                     /locus_tag="ACFOV4_001595"
     CDS             5838..6731
                     /locus_tag="ACFOV4_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HFC7619568.1"
                     /translation="MPHPCQTVHTLTARVPKCRLKLNAARRQRYNRPQLFFPNIIMTT
                     TEHDNDDAFLLRYSRHILLDEIGIEGQQKLSAAHILVVGCGGLGAAALPYLAASGIGT
                     LTIADSDTVELHNLQRQVAFDEGDVGKPKAEALADRLKRINHNVDVRTVNEKLDGCRL
                     TGLVQTADIVLDCCDNYATRQAVNRVCVQTKTPLVSGAAVRFEGQLAVYRPDLPDSPC
                     YACLFDGGSASDGICSLFGVFSPLVGIIGSTQAAEALKILLDAGEPSHGRLAVYRALE
                     GGWQYFDLPRNPECPICGAER"
     gene            complement(7131..7355)
                     /locus_tag="ACFOV4_001596"
     CDS             complement(7131..7355)
                     /locus_tag="ACFOV4_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SlyX family protein"
                     /protein_id="HFC7619569.1"
                     /translation="MDAVQELEHRITELEIQSALQEDVIAGLNAMVAELRQTLDLQQA
                     QLRLLYQKMQDRNPDTQEPYSLRDEIPPHY"
     gene            complement(7356..8744)
                     /locus_tag="ACFOV4_001597"
     CDS             complement(7356..8744)
                     /locus_tag="ACFOV4_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter family protein"
                     /protein_id="HFC7619570.1"
                     /translation="MNAVVVAVIVMLVLSLSRVHVVLSLTVGAFVGGAVAGMPLQNIA
                     DAAGQVSQAGIIPVFNKGLEGGAKIALSYAMLGAFAMAITHSGLPQQLAGAVVRKLNR
                     GGMPDSVRSGEGAVKWLLLSIILVMGMMSQNIIPIHIAFIPMIVPPLLLVFNRLKIDR
                     RLIVCVITFGLVTTYMFLPYGFGAIFLNEILLGNIHSAAPQLDVKNINVMAAMAIPAL
                     GMLAGLLLAFVHYRKPRLYQSNNADTAGNADAANRPQPSAYRSLAAAAAIAVCFAIQL
                     MYEDSLVLGAMLGFAVFMMLGVINRDKANDVFGEGIKMMAMVGFIMIAAQGFAAVMNA
                     TGHIQPLVESSMAIFGNSKGMAALAMLVVGLLVTMGIGSSFSTLPIIAAIYVPLCVGL
                     GFSPLATVAIVGTAGALGDAGSPASDSTLGPTMGLNADGQHDHIRDSVIPTFIHYNIP
                     LLIAGWIAAMVL"
     gene            complement(8830..9651)
                     /gene="prmC"
                     /locus_tag="ACFOV4_001598"
     CDS             complement(8830..9651)
                     /gene="prmC"
                     /locus_tag="ACFOV4_001598"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFC7619571.1"
                     /translation="MTFDKWLGLSKLPKNEARMLLQYVSEYTRVQLLTRGGEEMPDEV
                     RQRADRLAQRRLNGEPVAYILGVREFYGRRFTVNPSVLIPRPETEHLVEAVLARLPEN
                     GRVWDLGTGSGAVAVTVALERPDAFVRASDISPPALETARKNAADLGARVEFAHGSWF
                     DTDMPSEGKWDIIVSNPPYIENGDKHLSQGDLRFEPQIALTDFSDGLSCIRTLAQGAP
                     DRLAEGGFLLLEHGFDQGAAVRGVLAENGFSGVETLPDLAGLDRVTLGKYMKHLK"
     gene            complement(10166..11650)
                     /gene="tldD"
                     /locus_tag="ACFOV4_001599"
     CDS             complement(10166..11650)
                     /gene="tldD"
                     /locus_tag="ACFOV4_001599"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HFC7619572.1"
                     /translation="MPYNQAPDFLCADTMHPTYSAVQARLLEANRLSPELLAKSLCII
                     GAHHVDYADIYCQRTAYESWHLEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCI
                     DSINRSARAVRAIGAAGGKVSAKMPSETRGKPVCSASDPIAGLDSAAKVALLNKVEAI
                     AKAADPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQGSA
                     GGGGRYDLAYFDENLVRQFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAV
                     GHGLEGDFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVL
                     IEDGILVGYMQDETNARLTGTQSTGNGRRESYASVPMPRMTNTFMENGSYEPEEIIAS
                     IDKGIYAVNFGGGQVDITSGKFVFSASEAWWVEGGRLQYPVKGATIIGNGPEVLKHVS
                     MIGNDTALDSGVGVCGKEGQSVPVGVGQPTLRIDAGLTVGGSAI"
     regulatory      11828..11931
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11998..13221
                     /gene="cytX"
                     /locus_tag="ACFOV4_001600"
     CDS             11998..13221
                     /gene="cytX"
                     /locus_tag="ACFOV4_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003519479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydroxymethylpyrimidine transporter
                     CytX"
                     /protein_id="HFC7619573.1"
                     /translation="MSGNASSPSSSAAIGLIWFGAAVSIAEISTGTLLAPLGWQRGLA
                     ALLLGHAVGGALFFAAAYIGALTGRSSMESVRLSFGKRGSVLFSVANMLQLAGWTAVM
                     IYAGATVSSALGKVLWDGESFVWWALANGALIVLWLVFGARKTGGLKTVSMLLMLLAV
                     LWLSAEVFSTAGSTAAQVSDGMSFGTAVELSAVMPLSWLPLAADYTRQARRPFAATLT
                     ATLAYTLTGCWMYALGLAAALFTGETDVAKILLGAGLGAAGILAVVLSTVTTTFLDAY
                     SAGVSANNISAKLSETPIAVAVAVVGTLLAVLLPVTEYENFLLLIGSVFAPMAAVLIA
                     DFFVLKRREEIEGFDFAGLVLWLAGFILYRFLLSSGWESSIGLTAPVMSAVAIATVSV
                     RLFFKKTQSLQRNPS"
     gene            13218..14318
                     /locus_tag="ACFOV4_001601"
     CDS             13218..14318
                     /locus_tag="ACFOV4_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFC7619574.1"
                     /translation="MTRIAILGGGLSGRLTALQLAEQGYQIALFDKGCRRGEHAAAYV
                     AAAMLAPAAEAVEATPEVVRLGRQSIPLWRGIRCRLNTHTMMQENGSLIVWHGQDKPL
                     SSEFVRHLKRGGVADDEIVRWRADDIAEREPQLGGRFSDGIYLPTEGQLDGRQILSAL
                     ADALDELNVPCHWEHECAPEDLQAQYDWLIDCRGYGAKTAWNASAEHGSTLRGIRGEV
                     ARVYTPEITLNRPVRLLHPRYPLYIAPKENHVFVVGATQIESESQAPASVRSGLELLS
                     ALYAVHPAFGEADILEIATGLRPTLNHHNPEIRYSLARRLIEINGLFRHGFMISPAVT
                     AAAVRLAVALVDGKDAPERDEESGLAYIRRQD"
     gene            14339..14956
                     /gene="thiE"
                     /locus_tag="ACFOV4_001602"
     CDS             14339..14956
                     /gene="thiE"
                     /locus_tag="ACFOV4_001602"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFC7619575.1"
                     /translation="MTFPPLKSPLKFYAVVPTADWVGRMVKAGADTVQLRCKTLHGDE
                     LKREIARCVAACQGSRTQLFINDHWREAIEAGAYGVHLGQEDMDTADLAAIAAAGLRL
                     GLSTHSVAELDRALSVHPSYVASGAIFPTTTKQMPTAPQGLDKLCEYVKQAGGTPVVA
                     IGGIDLNNARAVLATGVSSLAAVRAVTEAANPEAVVKAFQALWDG"
BASE COUNT         3133 a         4314 c         4247 g         3504 t
ORIGIN      
        1 ctgtaatctt tagattgcca atgggaaacc gtctactaca aataaaaaac cctgcgataa
       61 gcagggtttt ttgaatttcc aacattaacg tttggagaat tgttttgcac ggcgtgcttt
      121 gcgcagaccc ggttttttac gttcaacttc gcgggcatcg cgggtaacaa aaccagcttg
      181 agacaaggcg ggtttcaacg cggcatcgaa gtcgatcagg gcacgggtaa tgccgtggcg
      241 gattgcgccg gactggccgg tttcgccgcc gccaacaaca ttgactttga tgtcgaaaga
      301 ttcggcgttt tcagtcagaa ccaagggttg gcgaacaacc attcggctgg tttcgcgtgc
      361 gaagaattcg tcaacgggac ggccgtttac gatgatttga cctgtacctt taatcaggaa
      421 tacacgagcc actgaacttt tgcggcggcc tgtgccgtag tagtatttac cgttcatgtc
      481 gcgtccttat ttcagttcca aaactttggg ttgttgcgca gcatgggcgt gttccgcacc
      541 cgcatacact ttcagttttt taatcatggc gtaacccaaa ggacctttgg gcagcatacc
      601 ttttacagct tgttccaaag cgcggcccgg gaattgctct tgcatttcgc ggaaagtgcg
      661 ttcgtagata ccgcctggga aaccggaatg gcggaagtat tttttatctt cgaatttggc
      721 accggttaca cgcagtttgt ccgcattgat aacaatgatg taatcgccgg tatcgacgtg
      781 gggggtgtat tcaggtttgt gtttgccacg cagacggctg gcgacttcgg ccgcaacgcg
      841 acccaagact ttgtcttggg catcgatgac gaaccattcg cgcttcacct cgtggggttt
      901 cgctgaaaag gttttcatag tggaaatcca gatagatata gaaagttgta aattttaaag
      961 acaggattcg attttgtcaa tcgcattacc gcgttacgga aggattttcc ggatttcggc
     1021 agactgcata ctgctttttc gggcggggcg gcggccaatg tgaaaaaccg catcgttgcg
     1081 atgcggtttt gaatgggaat ccccgcgaga gccgtttcgg ccgaatccgc ttgaaccttg
     1141 ctgacaaggc ggctgcctcg ggtagtttcg ggtgcgtccg caaaaggacg ctcgcgccca
     1201 ctactgctcc cggcaacctt aagcgaactt attggttcaa aggaatatat gccttcgcgg
     1261 acaccgcagg gaaaaagggg ttattcctgc gccaagcggg atagtgcttt ttggcaggcg
     1321 ttgtccatat cggctatttt acgcgcaaaa tcgccgattg ccaaatcgcc gccgttcagg
     1381 gaggttttca acaggtcgtg gacgacgttg agcgtggcca taatgacgat tttttcgctg
     1441 tccgcgacgc gtccgccttc gcggatggct tcggctttgc cgttgagcat tccgactgcc
     1501 tgcaacagtg tgtctttttc ttctgccggc gtgttgacgg tcagccgggc gtgcatgact
     1561 tcgatgtgga cttgttcgat gttcatcctt taatccttat tgctgcgttt cctgccattg
     1621 ggggaggcgc gctgccagtg cgctgatttt ttccctgctc tgttcgagca ggctgcggta
     1681 tcgtgtattt tcttctgtca ggctgtcaat tttgttttgc aggtcttctt tgagtttgcc
     1741 gacttggacg agcagggctt cgctgagttc gtcgacggcg gtttcgtgtt cgagtttttg
     1801 ccgctcgtgc gcccgtttga gttcggcgac ggtttctttg aggcggcggt tttcgctgac
     1861 gagggtttcg aatttttgta ccagcgtata aacgctgctt tcgagttttt cgatattttg
     1921 tttcataacc ttacctgtcc gtatgccgtc tgaaggcttc agacggcatc tgtctgttgt
     1981 ttattcgaaa cgcgcgctgc gttccatcag tctttcgacg acctgctgag gggtcatttc
     2041 tttgcggatg agttgcagca gggtttgggt aatcggcatg tcgatttggt acttacaggc
     2101 agtattgaag acttcttcta tcgtgctgac cccttcggaa acgtgtccga tttcgaccag
     2161 cacctgatgc agttccttgc cttctgccaa acccaagccg acgcggcggt tgcgtgagag
     2221 tgcgccggtg caggtcaaga tgaggtcgcc gatgccagca agccccatca tggttttggg
     2281 ctgtgcgccc attgcggagg caaggcgggt gatttcagct aatccgcgtg taaccagtgc
     2341 ggcacgggcg ttaagcccgt actccagacc gtcggacaat ccggtggcaa tcgccatgac
     2401 gtttttgact gcaccgccga ctgccacgcc gataacgtcg gtactgccgt aaagcctcat
     2461 gacggtcgtg ttgagctgcg gtacgagttc ttcaatccac tcttggtttt cggaggcgag
     2521 gacgacggcg cagggcagtt gtttggcgag ttcctgtgca aaactcggac cggaaagtac
     2581 gccgattttt ttattgtcgg gcaatacttc tttcaatact tgaaaggtca gcagccctgt
     2641 atcctgctcg aatcctttgc aggcggcgag gacggggagg tgtcccgcgc cgtactgttt
     2701 gagcagctct gcgctgcttc tcaatccggc aacggaggtt acgataagga caagtccgct
     2761 gtctttgagc gcgtctgcca aatccgcaca cacttccaag gtttcgggaa aggaaaagcc
     2821 gggcagtccg cgtttgtttt cacgcgcttc ctgcatttgg cggacttggt ctgcgttgcg
     2881 cgtccacagg gatacgcggt tgccgtgttg ggaaaaatgc agggcgagcg ccgtacccca
     2941 cgaacctgcg ccgataacgg taattttcat tggtcgtctt tcaacatatc actgccgttc
     3001 actttaaaac aatcggtgtt tctctgcaag tgcggtcagg gaaatgccgt ctgaaaggcg
     3061 ttcagacggc attttgcccc gatgcggcac tatcagcctg tattgcgcaa accttgcgcc
     3121 acgccgttga tggtcaggtg caccatcaga agggcgtgcg gattgtcggg ttctttacgc
     3181 aggcgtttga gcatggcgac ttgcaggccg ttgagggcgt tcaaatatgg aatcctcaag
     3241 gcaagcgaac gggcgaggct gcggttgtcg cgcaggagct cttcggtttg cagcaagtcg
     3301 agcagtgctt tgcggctgcg ttggtattct tccttgatca tgccgaagat gacttttgct
     3361 ttgtcgggtg attcgctcaa gccggcatag ttttccgcca aggtgatgtc ggttttcgcc
     3421 atcacttgtt ccatattgga gagcatggct tggaagaacg ggttgctttg ggcgtgttcg
     3481 cgcagggcgg cgagcgtttc gggtttgtct tcgcacaagg tttccaccgc gctgccgaaa
     3541 ccgtaccaag caggcagcat gaggcggttt tgcatccagg aaaataccca cggaatcgcg
     3601 cgcaagtctt gaatccgcgc taaggtcttg cggctggcgg gacggctgcc gaggttgagg
     3661 gtggcgattt cctgaatcgg gctggtttgc aggaagtagt cgatgaagtc ggggtgggta
     3721 atcagttcgc ggtagtattt gaacgatacg tccgacaatg cctgcatcag tttggcatca
     3781 gggtcttttt tatccggcag gatgctggct tccaaagtcg cggcaaccaa ggtttccaag
     3841 ttgcgttggg cattgccggg gtcggcgtat ttggcggtaa tgacttcgcc ttgttcggtg
     3901 atgcggattt gtcccgccac gctgcccgcc ggttgggcga gaatggcttg gtaagaaggg
     3961 ccgccgccgc gtccgacgct gccgccgcga ccgtggaaca ggcgcatgcg gacatcgtat
     4021 tttttgaaga gttcgaccaa gcccaattcc gcctgataga ggcaccatga gctggtaacg
     4081 tagccgccgt ccttgttgga gtcggaatag ccgagcataa tttcttggat attgccgcgg
     4141 ctttcgagca gggcatcgta ccagtcgagg cggaacatgg tttccatgac cggacaggcg
     4201 ttttccaacg cttcaatggt ttcaaacagc ggcacgatat tgatgcggct gcgcggtttg
     4261 ccgttttcca ccgccaacag gccgctttct ttcagcagca atgccaaggc gagcaggtcg
     4321 ctgggttgtt cgcagttgga aataatgctt tgtgttacgg catcttcgcc aaattcgtct
     4381 ttgattttgc gcgcttcgtt gaaaattgcc agttcgtggc gggtatggtc gctgtatgtg
     4441 ataaacgggc tgtacagcgg acgttgatgg ctcaattctc gcaacaggac ggcttgtttt
     4501 tgttcttcgt tcaggctgtt gtagtcttcc aagcctgcgt gttggaaaag ctcggtaacc
     4561 acatcggcgt gtttgcctgc gtgttggcgc aaatcaagcg gcatcatatg gaagccgaac
     4621 acggatacgg agcggatgag gtctgccaga cggccttcgg caagcaggcg gctgccgttg
     4681 tcgataaggg aacgttgcaa ttttttcaaa tcatcgagaa attcttgtgc cgaagcataa
     4741 ggctcgagga agccgaattt gcagcccatg cccaaaccga gtgagcgtgc cttgcccata
     4801 gcgcgtgcca tgatgtaggc gatggcgcgg cggtagggtt cttcggtacg ggcgatttct
     4861 tcgtcaggcg agagggcggc cagtgccatt acgtcgtcgt tgactttgac gcggcggatg
     4921 gagagcggca gttcgcggta aagtttgtcg agttcgccac ggtaaaaacg gaacacggca
     4981 tcggcgtggc ggcggaaggc aaaacgcaag gtttcggcag aaacgaacgg attgccgtcg
     5041 cggtcgccgc caatccagcc gccgattttg aggatattcg gaacgcagac atcgggatag
     5101 accatctgaa agtcgtgttc catcttgcgg tagagcttgg gcagggcttc gaaaaagctc
     5161 atcgggaaga tggacacgcc gttgttgatt tcgtcgttga cgctgagttt gtggcggcgc
     5221 gtttcgctgg tctgccacaa gcccagcagg atagtgtcga tttcgcggcg cagccgtgcc
     5281 agcgcgtcgg cattggtgca gcgttcgcgt tgcggcaaca gtgcgcggat gcggcggttg
     5341 aagcttaaga cggtttggcg ttgcacttcg gtcgggtgcg cggtcaaaac ggcggtaacg
     5401 gacgtattgt ccaactgccg ctgcaccgat ttgccgtcgg ctttccccgc tttgagcctg
     5461 cggacggttt ccgtcaggct gccttccgcg ccgccgcgtc cggcttcttc gtggatttgg
     5521 cggcggcgtt cgtggtgcac gtcttcggcg atgttcaaaa tctgtgcgaa caggccgcag
     5581 gccaaggtta aatcgtgggt ttgttgttcg tccaattgcg gcaatacttt ttcaatcaat
     5641 gccgcgctgt cgtcggaagt ggacaagagt ttgaccgttt cgacaaccaa tggcgaggct
     5701 tcttcgtgca ggaggttgaa cagggattgt ttcagaaatt ccgcgtccgc cgccaaagcc
     5761 gcgtcctttg gattgttcag aatatgcagt tgcatgattt ttctctcatt gccgtaaata
     5821 ctgtaaatgt acctcaaatg ccgcatccgt gccaaaccgt tcacacttta accgcccgtg
     5881 tcccgaaatg ccgtctgaag ttgaacgccg cccgacggca gcgttacaat cgcccacaac
     5941 tgttttttcc gaacatcatc atgaccacga ccgaacacga caacgacgat gcattcctgc
     6001 tgcggtacag ccgccacatc ctcttggacg aaattggcat cgaagggcag cagaaacttt
     6061 ccgccgcgca tattttggtc gtcggctgcg gcggtttggg tgccgccgcc ctgccctatc
     6121 tcgccgcttc cggcatcggc acgctgacca tagccgattc cgacacggtc gagctgcaca
     6181 acctgcaacg ccaagtcgca tttgacgagg gcgatgtcgg caagcccaaa gccgaagcct
     6241 tggcagaccg cctgaaacgc atcaaccata acgtcgatgt ccgcaccgtc aacgaaaaac
     6301 tcgacggctg ccgcctgacc ggtttggttc aaaccgccga catcgtttta gactgctgcg
     6361 acaactacgc cacgcgccaa gccgtcaacc gtgtctgcgt acaaacgaaa acaccgctgg
     6421 tttcaggagc agcggtgcgc tttgaagggc aacttgccgt gtaccgtccc gacttgcccg
     6481 actcgccgtg ttacgcctgc ctgtttgacg gcggatcggc ttcagacggc atctgttccc
     6541 tcttcggcgt gttctcgccg ctggtcggca tcatcggcag tacccaagcg gcggaggctc
     6601 tgaaaatcct gctggatgcg ggcgaaccgt cgcacggcag gctggcggtt taccgtgcct
     6661 tggaaggggg ctggcaatat ttcgacctgc cgcgcaaccc cgaatgcccg atttgcggcg
     6721 cggaacggta aaaccctgcc gccgtttcag acggtatcca aacggatgcg gcggaacggt
     6781 tttaaaaatt taaaaattta catttctttg caaaaaaaaa taaacttacc ttataattgc
     6841 agttgtttta gcaatgtctg tttcgcagac tcattgagta agacgttttc cccgtaatgt
     6901 gtttggccgt ctgtcccctt tgggttcgga cggctttttt taggctgtgt ttgaataccc
     6961 ggttggtttc gtctgtttgc aggggaaaac cgcttatttc cgttcgggcg gaaaacggtt
     7021 ccatcggata aaaggcattt tgtccgactg attaaagtta catcttaggt ttgcatcggc
     7081 aaaatattca aacacagcct tttttaagga aatccggata cggcggcaca tcaataatgc
     7141 ggcggaatct cgtcgcgcag ggaatacggc tcttgcgtgt cgggattcct gtcctgcatt
     7201 ttttgataca gcagcctcaa ctgagcctgc tgcaaatcca gcgtctgccg caattccgcc
     7261 accatcgcgt tcaggccggc gattacgtcc tcctgaagcg cggattggat ttccagctct
     7321 gtgatgcggt gttccaactc ttgaaccgcg tccatttaca gcaccatcgc ggcaatccag
     7381 ccggcaatca gcagcgggat attgtagtgg atgaaggtcg ggataacgga atcgcggatg
     7441 tggtcgtgct gcccgtcggc gttcagcccc atcgtcgggc ccagcgtgga atcggacgca
     7501 ggcgaaccgg catcgcccaa cgcccccgcc gtgccgacaa tggcgacggt ggcaagcggc
     7561 gaaaaaccca aaccgacaca caaaggcaca taaatcgcgg caataatcgg caaagtggaa
     7621 aaggacgaac cgatgcccat cgttaccaaa agccccacca ccagcatcgc caatgccgcc
     7681 atacctttgc tgttgccgaa tatcgccata ctgctttcca ccagcggctg gatatgcccg
     7741 gtcgcattca tcacggcggc aaaaccctgc gcggcaatca taatgaagcc gaccatcgcc
     7801 atcatcttga taccttcgcc gaatacgtcg tttgccttgt cgcggttgat gacccccaac
     7861 atcataaata cggcgaaacc gagcatcgcg cccaacacca gcgagtcttc atacatcaac
     7921 tggatggcaa aacatacggc aatggcggcg gcggcggcca ggctgcggta ggcggacggc
     7981 tgcggacggt ttgccgcatc ggcgttgccc gccgtatcgg cattgttgct ttggtacagg
     8041 cgcggtttgc ggtaatggac aaacgccagc aggagtccgg ccagcattcc caacgcggga
     8101 atcgccattg ccgccatcac gttaatgttt ttcacatcaa gctgcggcgc ggcggaatgg
     8161 atgttgccca acaggatttc gttcaaaaaa atcgcgccga agccgtaagg caggaacata
     8221 taagtcgtaa ccagcccgaa agtgatgacg cacacaatca ggcggcggtc gattttcagg
     8281 cggttgaaca ccaaaagcag cggcggaaca atcatcggga taaaggcaat gtggatgggg
     8341 atgatgttct gactcatcat gcccatcaca aggatgatgg aaagcagcag ccatttgacc
     8401 gcgccctcgc ccgaacgcac gctgtcgggc ataccgcccc ggttcagttt gcggacgacc
     8461 gcgccggcaa gctgctgcgg caggccggaa tgggtaatcg ccatcgcaaa cgcaccgagc
     8521 atcgcataag aaagcgcaat cttcgcgccg ccttccaaac ctttgttgaa cacggggata
     8581 atccccgcct gactgacctg tcccgccgca tcggcaatgt tttgcagcgg catacccgcc
     8641 accgcgccgc cgacaaacgc gccgaccgtc aggctcaata ccacgtgcac gcgcgacagc
     8701 gacagcacca gcataacgat tacggcaact acgactgcat tcattgttta tcgctccaaa
     8761 cctataaatg tttacatatc gaaacacatc ataacccaat aacggaaaac ccgccaattt
     8821 tgcaaacaat tatttcaaat gcttcatata cttccccagc gtaaccctgt ccaaacccgc
     8881 caagtccggc agggtttcca ctcccgaaaa accattctcc gccaacacgc cgcgcaccgc
     8941 cgcgccctga tcgaaaccgt gttccagcaa taaaaaaccg ccttccgcca aacggtcggg
     9001 cgcgccttgc gccaaggtac ggatgcagct taggccgtct gaaaagtcgg tcagcgcgat
     9061 ttgcggctca aaccgcaaat cgccttgcga caaatgttta tcgccgtttt cgatataggg
     9121 cgggttggac acgatgatgt cccatttccc ttcagacggc atatcggtgt cgaaccacga
     9181 accgtgtgca aattcgaccc gcgcgcccaa atccgccgca tttttccgcg ccgtttcaag
     9241 ggcgggcggg ctgatgtcgg atgcgcgcac aaacgcatcg gggcgttcga gcgcgacggt
     9301 tacggcaacc gcgccgctgc ccgtccccaa atcccacacg cgcccgtttt cgggcaggcg
     9361 cgccaatacg gcttcgacca agtgttcggt ttcggggcgc ggaatcagca cgctcggatt
     9421 gactgtaaag cgtctgccat aaaattcgcg cacacctaaa atataggcaa ccggctcgcc
     9481 gttcagacgg cgttgcgcca gcctgtccgc ccgctgtcgg acttcgtccg gcatttcttc
     9541 cccgccccgc gtcaacaact gcacgcgcgt atattccgaa acatattgca gcagcattct
     9601 tgcttcattt ttaggcagtt ttgacaagcc caaccattta tcaaacgtca tttttatccc
     9661 gtctgccgct gatgcggctt ttctttcctt attctttccg gcaaacgtac cgatggtggc
     9721 aaccgcaaat gcggcatacc acaaataaaa tcctgcaccg tagcgcacaa tatccgatgt
     9781 attccctgct tcatcgacgt atacggcttt cacactgaaa gccaccaacg ccaagcccca
     9841 aagtgccgca tggacaggca cgaccttctt ccgcaacgcc agcaaaacaa tggccgccaa
     9901 ccaaacataa ttcgcataga ccgcacaata cctgatatcc aaagaagcaa atatcgaccc
     9961 caaaatcaaa acggtcaaac cctccatgct tccatgattg cccaaataaa atgcaacatt
    10021 ggataaagac gctatccaca gggcaaccga caccagcaac atcactatgg gaaaacttga
    10081 tttccgattc tgttcctgca tggttttatc ctaatgtaaa aggccgcctg aaaacctttc
    10141 agacggcatc gtgccggatt ccgcgtcaga ttgcgctgcc gccgacggtc agcccggcat
    10201 cgatacgcag ggtcggctgc cccacgccga cggggacgct ctgcccttct ttgccgcaca
    10261 cgccgacacc gctgtccaac gcggtatcgt tgcctatcat cgaaacgtgt ttcagcactt
    10321 cgggcccgtt gccgataatg gtcgcgcctt tgacggggta ttgcagcctg ccgccttcca
    10381 cccaccatgc ttcggacgcg ctgaacacaa atttgccgct ggtaatgtcc acctgtccgc
    10441 cgccaaagtt gacggcgtaa atgcctttgt cgatggacgc gatgatttct tccggctcat
    10501 agctgccatt ttccataaag gtattggtca tgcgcggcat cgggacggag gcgtagcttt
    10561 cgcggcggcc gttgccggtg gattgcgtac ccgtcaggcg ggcattggtt tcgtcctgca
    10621 tatagccgac taaaatgccg tcttcaatca atacggtgcg gcgggtttcg ttgccttcgt
    10681 cgtcgatgtt gagcgaaccg cgccggccgg caatatcgcc ctgatcgacg acggtaacgc
    10741 ctttggcggc gacgcgctcg cctattctgc cggaaaagac gctggtcccc ttgcggttga
    10801 aatcgccttc caaaccgtgt ccgaccgctt cgtgcagcaa cacgcccggc cagccgttgc
    10861 ccaaaacgac ggtcatttcg ccggcgggcg cggggcggga ttcgaggttg gtgagtgcct
    10921 gtttgacggc ggcatcgaca aactgccgca ccaagttttc atcgaaataa gccaagtcgt
    10981 agcgtccgcc gccgcccgcg ctgccctgtt cgcggcgttc gccctgtttg gcgatgacgg
    11041 taacgttcag gcgcaccatc gggcggatgt cggcggcgtg tttgccgtcc agacgggcga
    11101 ggtaaaccat atcgtattcg caggtcaaac cggccatcac ttgcacgatg cgcggatcgg
    11161 cggctttggc gattgcttcc actttgttca acagcgcgac tttggcggcg gaatcgaggc
    11221 cggcaatggg gtcggacgcg gaacaaaccg gcttgccgcg cgtttcagac ggcattttgg
    11281 cggacacctt gccgcctgcc gccccaatcg cgcggacggc gcgggcggaa cggtttatcg
    11341 aatcgatgca caggctgtcg gcgtaggcaa aggcggtttt atcgcccgaa acggcgcgca
    11401 cgcccacgcc ctgattgatt tggaagctgc ccgatttgac gatgccctct tccaaatgcc
    11461 agctttcata agcggtgcgc tggcagtaga tgtcggcgta atcgacgtgg tgcgcgccga
    11521 tgatgcacag gcttttggcg agcagttcgg gggaaaggcg gttggcttcg agcagccgcg
    11581 cctgtacggc ggaataggtc ggatgcatag tgtcggcgca taaaaaatca ggggcttgat
    11641 tatacggcat ttgttatata gtggattaac aaaaaacagt acggtgttgc ctcgccttgc
    11701 cgtactattt gtactgtctg cggcttcgtc gccttgtcct gatttttgtt aatccactat
    11761 agaaatgcgc cgtgccgcct gaaatgtaag atttttgcca acgccccctg cttttgtgta
    11821 cacttaaagc tccttgtcgg agtgccgccg ccgggcggct gagattgcga aagcagaatc
    11881 cgtagaacct gtcggggtaa tgcctgcgta ggaaacaaac cgtcaaatgc cttatcaggc
    11941 ttccgttccc ttttccgcac ttccccgccc accttccttc tttttaaagg acgtcatatg
    12001 tcgggcaatg cctcctctcc ttcatcttcc gccgccatcg ggctgatttg gttcggcgcg
    12061 gcggtctcga ttgccgaaat cagcacgggt acgctgcttg cgcctttggg ctggcaacgc
    12121 ggtctggcgg ctctactttt gggtcatgcc gtcggcggcg cgctgttttt tgcggcggcg
    12181 tatatcggcg cactgaccgg acgcagctcg atggaaagcg tgcgcctgtc gttcggcaaa
    12241 cgcggttcag tgctgttttc cgtggcgaat atgctgcaac tggccggctg gacggcggtg
    12301 atgatttacg ccggcgcaac ggtcagctcc gctttgggca aagtgttgtg ggacggcgaa
    12361 tcttttgtct ggtgggcatt ggcaaacggc gcgctgattg tgctgtggct ggttttcggc
    12421 gcacgcaaaa caggcgggct gaaaaccgtt tcgatgctgc tgatgctgtt ggcggttctg
    12481 tggctgagtg ccgaagtctt ttccacggca ggcagcaccg ccgcacaggt ttcagacggc
    12541 atgagtttcg gaacggcagt cgaattgtcc gccgtcatgc cgctttcctg gctgccgctg
    12601 gccgccgact acacacgcca agcacgccgc ccgtttgcgg caaccctgac ggcaacgctc
    12661 gcctatacgc tgacgggctg ctggatgtat gccttgggtt tggcagcggc gttgttcacc
    12721 ggagaaaccg acgtggcaaa aatcctgctg ggcgcaggtt tgggtgcggc aggcattttg
    12781 gcggtcgtcc tgtcgaccgt taccaccact tttctcgatg cctactccgc cggcgtaagt
    12841 gccaacaata tttccgccaa actttcggaa acacccatcg ccgttgccgt cgccgttgtc
    12901 ggcacactgc ttgccgtcct cctgcccgtt accgaatatg aaaacttcct gctgcttatc
    12961 ggctcggtat ttgcgccgat ggcggcggtt ttgattgccg actttttcgt cttgaaacgg
    13021 cgtgaggaga ttgaaggctt tgactttgcc ggactggttc tgtggctggc gggcttcatc
    13081 ctctaccgct tcctgctctc gtccggctgg gaaagcagca tcggtctgac cgcccccgta
    13141 atgtctgccg ttgccattgc caccgtatcg gtacgccttt tctttaaaaa aacccaatct
    13201 ttacaaagga acccgtcatg acccgtatcg ccatcctcgg cggcggcctc tcgggaaggc
    13261 tgaccgcact gcagcttgca gaacaaggtt atcagattgc acttttcgat aaaggctgcc
    13321 gccggggcga acacgccgcc gcctatgttg ccgccgccat gctcgcgcct gcggcggaag
    13381 cggtcgaagc cacgcccgaa gtggtcaggc tgggcaggca gagcatcccg ctttggcgcg
    13441 gcatccgatg ccgtctgaac acgcacacga tgatgcagga aaacggcagc ctgattgtgt
    13501 ggcacggaca ggacaagcca ttatccagcg agttcgtccg ccatctcaaa cgcggcggcg
    13561 tagcggatga cgaaatcgtc cgttggcgcg ccgacgacat cgccgaacgc gaaccgcaac
    13621 tcggcggacg tttttcagac ggcatctacc tgccgaccga aggccagctc gacgggcggc
    13681 aaatattgtc tgcacttgcc gacgctttgg acgaactgaa cgtcccttgc cattgggaac
    13741 acgaatgtgc ccccgaagac ctgcaagccc aatacgactg gctgatcgac tgccgcggct
    13801 acggcgcaaa aaccgcgtgg aatgcttctg ccgaacacgg cagcaccctg cgcggcatac
    13861 gcggcgaagt ggcgcgggtt tacacacccg aaatcacgct caaccgcccc gtgcgtctgc
    13921 tccatccgcg ttatccgctc tacatcgccc cgaaagaaaa ccacgtcttc gtcgtcggcg
    13981 cgacccaaat cgaaagcgaa agccaagccc ctgccagcgt gcgttccggg ctggaactct
    14041 tatccgcact ctatgccgtc catcctgcct tcggcgaagc cgacatcctc gaaatcgcta
    14101 ccggcctgcg ccccacgctc aaccaccaca accccgaaat ccgttacagc ctcgcccgac
    14161 gcctgattga aatcaacggc cttttccgcc acggcttcat gatttccccc gccgtaaccg
    14221 ccgccgccgt cagattggca gtggcactgg ttgacggaaa agacgcgccc gaacgtgatg
    14281 aagaaagcgg tttggcgtat atccgaagac aagattaaag ccgtctgaaa ggaaccccat
    14341 gaccttcccg cccttgaaat ccccgctcaa attctacgcc gtcgtcccca ccgccgattg
    14401 ggtggggcgc atggtcaaag caggtgccga cacggtgcaa ctgcgctgca agaccctgca
    14461 cggcgatgaa ttgaaacgcg aaatcgcccg ctgcgtcgcc gcctgtcaag gcagccgtac
    14521 gcagcttttc atcaacgacc actggcgcga ggcaatcgaa gcaggcgcgt acggcgtgca
    14581 tctcggacaa gaagacatgg acaccgccga ccttgccgcc atcgccgccg ccggtttgcg
    14641 cttgggtttg agtacgcact ccgttgccga actcgaccgc gccctgtccg tacaccctag
    14701 ctacgtcgcc agcggcgcga ttttcccgac cacgaccaag caaatgccca ccgccccgca
    14761 aggcttggac aaactgtgcg agtatgtgaa acaggcaggc ggcacgcccg tcgtcgccat
    14821 cggcggtatc gacttgaaca acgcccgagc cgtactcgcc accggcgttt cctcactcgc
    14881 cgccgtccgc gccgtaaccg aagcggcaaa tcccgaagcg gtggttaaag cgtttcaggc
    14941 tttgtgggat ggataaaacc gaaagaagaa aattcaattt gccgtgtcgg caaaacttag
    15001 cccgttatcg caaacatact taactttaaa tgtggcatat catcaaattc cgtcatttcc
    15061 gcgcaagcgg gaatccgcct taaaacttga gaaaccatca tttgaaaaac agtttccgaa
    15121 tttcaaaaat ggattcccgc ctgcgcggga atgacggcaa ccggccggtt gcgtatcaaa
    15181 aaataaagta attcggct
//
LOCUS       DAXISH010000053        14395 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.053, whole genome shotgun sequence.
ACCESSION   DAXISH010000053 DAXISH010000000
VERSION     DAXISH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 14395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14395
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.053"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            1..304
                     /locus_tag="ACFOV4_001603"
                     /pseudo
     CDS             1..304
                     /locus_tag="ACFOV4_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153708080.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(689..1111)
                     /locus_tag="ACFOV4_001604"
     CDS             complement(689..1111)
                     /locus_tag="ACFOV4_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HFC7619576.1"
                     /translation="MALIKEPLDKAKQRNEELEAAEEAAAQEALGREQEVDRVSEWEE
                     RYKLSRSEFEQLWKGLPQTVQNKLQASQKTWKSGMDKICANNAKAEGETPNGIKVSEL
                     ACKTVETEARLEELYNRKKALIDEMVREADKKELPKRL"
     gene            complement(1254..2900)
                     /gene="pgi"
                     /locus_tag="ACFOV4_001605"
     CDS             complement(1254..2900)
                     /gene="pgi"
                     /locus_tag="ACFOV4_001605"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFC7619577.1"
                     /translation="MKHFHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVG
                     GLTLDYSKNRINDETMSLLFELAREAGVPERMRQMFHGEKINTTENRAVLHVALRNRT
                     NSPIVVDGEDVMPKVNRVLQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPL
                     MMCTALKPFGHPRLNMHFVSNVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNAL
                     TAREWFLNHAGDEEAVAKHFAAVSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIG
                     LPIMLYLGEENFIEMLNGAHLMDQHFINTPLERNLPVILALIGIWYINYYGGGSHVIA
                     PYDQHLHRLPKFIQQLDMESNGKQVTLDGKAVGHETSPIIWGETGINGQHAFFQLLHQ
                     GTHITPIDLIASLEKRSNLPGHHEILLANVFAQAEAFMRGKTPDEVRAELKAQGMDEA
                     RIEELVPHKTFSGNRPTNLILMDKVNPRNMGSLIAMYEHKTFVQGIIWGINSFDQWGV
                     ELGKQLAKTILGELTGETGSQKHDSSTERLINLYLQTNRK"
     gene            complement(3021..3869)
                     /gene="hexR"
                     /locus_tag="ACFOV4_001606"
     CDS             complement(3021..3869)
                     /gene="hexR"
                     /locus_tag="ACFOV4_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HFC7619578.1"
                     /translation="MLSKISESLANLSGAERKVAECALAEPKWFVHAAVAEIAERASV
                     SQPTVIRFCRSLGYKGLPEFKLALSASIGHEGMPYVHEELNADDDMASVVEKVLGNAA
                     ASLLGERRFLKESELENAIATLMHARRVEFYGVGNSGIVAQDAQHKFFRFGMSTVAYV
                     DTHTQLMAASVLSDQDVLVAISNTGSSIELLDAVSIAKENGASVIALTRNDSPLAQLA
                     DCVLSVATQENAELYTPMVSRLLQLAVIDILAIGLALRLGDAASLQLQKSKKSIHNKH
                     IDYDKD"
     gene            complement(3919..4905)
                     /locus_tag="ACFOV4_001607"
     CDS             complement(3919..4905)
                     /locus_tag="ACFOV4_001607"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005536 - D-glucose binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HFC7619579.1"
                     /translation="MSSTPNKQAGYPRLVADIGGTNARFALETAPRVIEKAAVLPCKD
                     YDTVTDAVRAYLNQSGATAVRHAAFAIANPILGDWVQMTNHHWAFSIETTRQTLGLDT
                     LILLNDFTAQALAVTQTSSKDLMQVGGQKPVEFAPKAVIGPGTGLGVSGLVHSHAGWV
                     ALAGEGGHTSFPPFDDMEVLIWQYAKNKYGHVSAERFLSGAGLSLVYEALAAKQKAKP
                     AKLMPSEITEKALSGASPLCRQTLDIFCAMLGTVASNLALTLGARGGVYLCGGIIPRV
                     LEYFKTSPFRSRFENKGRFEAYLAAIPVYVVLSEFPGISGAAAALDNHLRNV"
     gene            complement(4886..5581)
                     /gene="pgl"
                     /locus_tag="ACFOV4_001608"
     CDS             complement(4886..5581)
                     /gene="pgl"
                     /locus_tag="ACFOV4_001608"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HFC7619580.1"
                     /translation="MFVWHEYENAAEAAQSLADAVADALQGALDEKGGAVLAVSGGRS
                     PIAFFNALSQKDLDWKNVGITLADERIVPTVHADSNTGLVREYLLKNKAEAAMWIPMV
                     EDGKTETELHPDAVVDYALKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGV
                     ALVHTTPVTAPHERVSMTLDAIAHTGHVFLAIRGEEKKAVFDQAAQGENREYPINLVL
                     NHQGVNCHVFYAE"
     gene            complement(5924..7369)
                     /gene="zwf"
                     /locus_tag="ACFOV4_001609"
     CDS             complement(5924..7369)
                     /gene="zwf"
                     /locus_tag="ACFOV4_001609"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFC7619581.1"
                     /translation="MSTQTNFDLVLFGATGDLAMRKLLPCLYQAHVAGLLHPEGRILG
                     VSRSELDTEGFLAKVETSSKIHVKENFSDEAWASFVERLAYLKVDVTQPDDFAALGDL
                     VKARKETDNVVIYLSTAPKFFAQTCENLAKIGLNADNVRVVLEKPLGTDLASSQQINT
                     DVARYFKEGQIYRIDHYLGKESLQNLLALRFANVMFEPLWNNKYIESVQLTIAEQLGV
                     EERGEFYDITGALRDMVQNHLMQMLCMTAMEAPASLDADAVRDEKVKVIKSLKPLTVE
                     SVNENVVRGQYTAAKGMNGYLEEINVPQDSFTETYVAIKAEIENERWKGVPFYLRTGK
                     RMAGKVAEIVLNFKDLNSHIFEGSRTAPNRLVIELQPYESVRLYTQMKTPGAGNKVET
                     VPLATDLGKALEGRRAEAYERLLLDVINGKLALFNRRDELEAAWEYVMPILENWANNT
                     TPPHGYGAHSWGPEAARELLARDGHKWHEEQ"
     gene            7885..9720
                     /gene="edd"
                     /locus_tag="ACFOV4_001610"
     CDS             7885..9720
                     /gene="edd"
                     /locus_tag="ACFOV4_001610"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HFC7619582.1"
                     /translation="MNTTPIHSKLAEITGRIIERSRPTREKYLAKIRSAKQMGRLERN
                     QLGCSNLAHGYAAMPKSIKIEMLQETVPNLGIITAYNDMVSAHQPFKDFPDQIKDEAQ
                     KNGATAQVAGGTPAMCDGITQGYAGMELSLFSRDVIAMSTAVGLSHQMFDGSLFMGVC
                     DKIVPGLMIGALSFGHIPGIFVPAGPMSSGIGNKEKARTRQLFAEGKVGRNELLKSEM
                     GSYHSPGTCTFYGTANSNQMMMEMMGVHLPAAAFVHPYTDLREALTRYAAGHLARGIK
                     NGTIKPLGEMLTEKSFINALIGLMATGGSTNHTMHLVAMARAAGVILNWDDFDEISSI
                     IPLLIRVYPNGKADVNHFTAAGGLPFVIRELLNAGLLHDDVDTVVGHGMRHYTKEPFL
                     IDGKLEWREAPETSGNDDILRKADNPFSPDGGLRLMKGNIGRGVIKVSAVREGCRIIE
                     APAIVFNDQREVLAAFERGELERDFVCVVRYQGPRANGMPELHKLTPPLGILQDRGFK
                     VALLTDGRMSGASGKVPASIHMTPEALMGGNIAKIRTGDLIRFDSVTGELNVLINEAE
                     WNAREVESIDLGANQQGCGRELFANFRSMTSSAETGAMSFGGEFA"
     gene            9901..10539
                     /locus_tag="ACFOV4_001611"
     CDS             9901..10539
                     /locus_tag="ACFOV4_001611"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_function: GO:0016833 - oxo-acid-lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFC7619583.1"
                     /translation="MSKLTPREILTAGAVVPVMAIDDLSTAVDLSHALVEGGIPTLEI
                     TLRTPVGLDAIRLIAKEVPNAIVGAGTVTNPEQLKAVEDAGAVFAISPGLHESLAKAG
                     HNSGIPLIPGVATPGEIQLALEHGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTG
                     GISLATAPDYLALPNVLCVGGSWLTPKEAVKNKDWDTITRLAKEAAALKPKA"
     gene            10554..10772
                     /locus_tag="ACFOV4_001612"
     CDS             10554..10772
                     /locus_tag="ACFOV4_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619584.1"
                     /translation="MPSEALSSLRRHFAAWRRSRHTRQHHSDILPLKCPSAFRIIKIT
                     FSSFDSSRTAHTTRLKKCRLKRIQTASA"
     gene            complement(10796..11741)
                     /locus_tag="ACFOV4_001613"
                     /pseudo
     CDS             complement(10796..11741)
                     /locus_tag="ACFOV4_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225132.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
     gene            11904..12944
                     /gene="mutY"
                     /locus_tag="ACFOV4_001614"
     CDS             11904..12944
                     /gene="mutY"
                     /locus_tag="ACFOV4_001614"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFC7619585.1"
                     /translation="MNTPIPFSERLIRWQKQHGRHHLPWQVKNPYCVWLSEIMLQQTQ
                     VATVLDYYPRFLEKFPTVQTLAAAPQDEVLSLWAGLGYYSRARNLHKAAQQVVRQFGG
                     TFPSERKDLETLCGVGRSTAAAISAFSFNRRETILDGNVKRVLCRVFARDGNPQDKKF
                     ENSLWTLAESLLPSENADMPAYTQGLMDLGATVCKRTKPLCHQCPMADICEAKKQNRT
                     AELPRKKTAAEVPTLPLYWLIVRNRDGAILLEKRPAKGIWGGLYCVPCFESLNGLSDF
                     AAKFSLTMADMDEQTALTHRLTHRLLMITPFEGQMPSESPSDGIWIKPAHLKDYGLPK
                     PLEIYLNGNRLE"
     gene            13361..13921
                     /gene="sodC"
                     /locus_tag="ACFOV4_001615"
     CDS             13361..13921
                     /gene="sodC"
                     /locus_tag="ACFOV4_001615"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC"
                     /protein_id="HFC7619586.1"
                     /translation="MNMKTLLALAVSAVCSVGVAQAHEHNTIPKGASIEVKVQQLDPA
                     NGNKDVGTVTITESNYGLVFTPDLQGLSEGLHGFHIHENPSCEPKEKEGKLTAGLGAG
                     GHWDPKGAKQHGYPWQDDAHLGDLPALTVLHDGTATNPVLAPRLKHLDDVRGHSIMIH
                     TGGDNHSDHPAPLGGGGPRMACGVIK"
     gene            complement(14260..>14395)
                     /locus_tag="ACFOV4_001616"
     CDS             complement(14260..>14395)
                     /locus_tag="ACFOV4_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFC7619587.1"
                     /translation="LHRKFRYARAAYFGLIKVSAQSHLKAMCLNLLKAANRLSAPAAA
                     "
BASE COUNT         3385 a         3914 c         3604 g         3492 t
ORIGIN      
        1 cggctcaata tgttgggcaa cacccggatg cctatctgca tgaaatcgcc aaacattttg
       61 attgtacggc agccaccatt tgctatgcac tcaaacagat ggggataacg cgcaaaaaaa
      121 gaccaccact tacaaagaac aagacccggc caaagtaacg cattatttga cacagccggc
      181 cgaattttcc gactaccaac gtgtttattt ggatgaaata ggatttgacc gctacctgtt
      241 ccgtccctat gcccgcagcc tgaaagggca aatagtgaaa gcgcagataa gtggaaaaag
      301 atatagtgga ttaacaaaaa tcaggacaag gcgacgaagc cgcagacagt acaaatagta
      361 cggaaccgat tcacttggtg cttcagcacc ttagagaatc gttctctttg agctaaggcg
      421 agccaacgct gtatcggttt aaatttaatt cactataaaa acgacaaaaa cgcaaaagcc
      481 gccgacattc ccgcatccaa gtttcagtca atcagataac cttggatttc tttggttttc
      541 gcattgattt ctctggtacg gcagtcagat tgtgccacgc cgtattcgtc gccgtcggcg
      601 catttggcat tcaaaccgtt ttgtcagttg cggtactcgg gcatgacggt ttcggcaata
      661 tcggcgggca gtgcctgaac cgcgctgttc agagccgctt tggcagttct ttcttgtccg
      721 cttccctgac catttcgtcg ataagggctt ttttacggtt gtacagctct tccaagcgtg
      781 cttcggtttc caccgttttg catgccagtt cgctgacttt tatgccgttt ggcgtttcac
      841 cttcggcttt cgcattgttg gcacagattt tgtccatacc gcttttccat gttttctgtg
      901 aggcttgcag cttattctgt acggtttgag gcaatccttt ccagagctgc tcgaactcgc
      961 tgcgcgacag cttgtagcgt tcttcccatt cggatacgcg gtcgacttcc tgctcccgac
     1021 ccaatgcctc ctgcgccgcc gcttcttctg ccgcttcaag ttcttcgttc ctttgtttcg
     1081 ctttgtccaa cggctcttta atcagtgcca tagctgcgga acatatatgt ttaaatttat
     1141 gcaaaccatc atatcgggat tgcacacgct ctgcaagttt accgacggtt ttcctgttcg
     1201 ataaaaatgc cgtttgaaac ggtcggcgtt cagacggcat ttttccgcag gttttatttg
     1261 cggttggtct gcaggtagag gttgatcagg cgttcggtcg agctgtcgtg cttttgcgac
     1321 ccggtttcgc cggtcagttc gcccaaaatg gttttagcca gttgtttgcc gagttccacg
     1381 ccccactggt cgaagctgtt gatgccccaa atgatgcctt gtacgaaggt tttgtgttcg
     1441 tacatggcaa tcaggctgcc catattacgc gggttgacct tgtccatcag gatgaggttg
     1501 gtcgggcggt taccggagaa ggttttgtgc gggaccagct cttcgatgcg cgcctcatcc
     1561 ataccctgcg ctttgagttc ggcgcggact tcgtcggggg ttttgccgcg cataaaggct
     1621 tctgcttggg cgaagacgtt ggcaagcagg atttcgtggt gtccgggcag gttgctgcgt
     1681 ttttcaagcg aggcaatcag gtcgatgggg gtaatgtgcg tgccttggtg cagcagttgg
     1741 aagaaggcgt gctggccgtt aatgcccgtt tcgccccaga taatcggcga ggtttcgtgt
     1801 ccgactgctt tgccgtccaa cgtaacctgt ttgccgttac tttccatatc gagctgctgg
     1861 atgaatttgg gcaggcggtg caaatgttgg tcgtaaggcg cgatgacgtg gctgccgccg
     1921 ccgtagtagt tgatatacca gatgccgatg agggcgagaa tgacgggcag gttgcgctcg
     1981 agcggtgtgt tgatgaagtg ttggtccatc aggtgcgcgc cgttgagcat ttcaatgaag
     2041 ttttcttcgc cgagatacag cataatcggc aatccgatgg cggaccacag gctgtaccga
     2101 cctccgaccc aatcccaaaa ttcaaacata ttggcggtgt cgatgccgaa ttcggcgacg
     2161 gctttttgat tggtggaaac ggcggcgaag tgtttggcaa cggcttcttc gtcgcccgca
     2221 tgattcaaaa accattcgcg cgcggtcagc gcgttggtca gcgtttcctg cgtggtaaat
     2281 gttttggagg cgatgatgaa cagcgtggtt tcggggtgga ctttggacaa tacgtcgcgc
     2341 agttgggagc cgtccacgtt ggagacgaag tgcatattga ggcgcggatg accgaaaggt
     2401 ttgagcgcgg tacacatcat cagcgggccc aaatccgatc cgccgatgcc gatgttgaca
     2461 acgtcggtaa tgacttggtt ggtatagccc agccagcttc cgctgcggac ttcgtgtgca
     2521 aattcgccca tacgttgcaa aacgcggttg actttgggca tcacatcttc accgtcaacc
     2581 acaatcggcg aattggtgcg gttgcgaagg gcgacatgca ggacggcgcg gttttcggtg
     2641 gtattgattt tttcgccgtg gaacatctgc cgcatccgct ccggcacgcc tgcttctcgg
     2701 gcaagctcga acaaaagcga catggtttcg tcgttgatgc ggtttttgga gtagtccagc
     2761 gtcagtccgc cgacttgcag ccagtagcgt tccgcacgct gcgggtcttg ctcgaacatt
     2821 tcgcgcatat gcaatgtttt gctgtcgtca aagtggttcc acaatttcga ccatgcgggt
     2881 aagtcgtgaa agtgtttcat ctatatgctc ctgaatgagg ttttttgttg tgggatgaaa
     2941 aggctgctgg aaactgccgc aagccgccga cggccgttgt tcggcatttc agacggcatt
     3001 tgtgggatgc cgtctgaagg tcaatctttg tcgtaatcga tgtgcttgtt gtgtatgctt
     3061 tttttgcttt tctgcaattg caggctggca gcatcgccca agcgcagggc aagtccgatg
     3121 gcgagaatgt cgatgacggc aagctgcaag aggcgggaaa ccatgggcgt gtagagttcg
     3181 gcattttcct gtgtggcaac gctcaacacg cagtcggcaa gttgcgccag aggcgaatcg
     3241 ttgcgggtca gtgcgatgac ggacgcgccg ttttctttgg cgatgctgac cgcatccaaa
     3301 agttcgatag acgaacccgt gttggaaatg gcaaccaaaa catcctgatc gctcaaaacg
     3361 gatgctgcca tcagctgcgt gtgcgtatcg acataggcga ccgtggacat tccgaaacgg
     3421 aaaaacttgt gttgcgcgtc ctgcgcaacg ataccggaat tgccgacacc gtaaaactcg
     3481 acgcggcggg cgtgcatcag cgtggcaatg gcgttttcca gctccgactc tttcaggaag
     3541 cggcgttcgc ccaacagcga ggcggcggca ttgcccaaca ctttctcgac cacgcttgcc
     3601 atatcgtcgt cggcgttgag ttcttcatgg acatagggca taccctcatg accgatgctg
     3661 gcggacaacg cgagcttgaa ctcgggcagc cctttataac ccaagctgcg gcagaatcgg
     3721 atgacggtcg gctggctgac ggacgcacgt tcggcaattt cggcaacggc ggcatggacg
     3781 aaccatttgg gttccgccaa tgcacattcg gcgactttgc gttccgcacc ggaaaggttt
     3841 gccagtgatt cgctgatttt gcttaacata atgatatgcc cttcgataat gcagccccgc
     3901 tgcaaggagc cgctgtggtt aaacgtttct caaatggttg tcgagagccg cagccgcacc
     3961 agaaattccg ggaaactcgc tcaagacgac atacacggga atcgcggcaa gatatgcttc
     4021 aaacctgccc ttgttctcga aacggctgcg gaacggggaa gttttgaaat attccaacac
     4081 gcggggaata atgccgccac acaggtacac gccgccgcgc gcgcccagcg tcagggcgag
     4141 gttggaagca accgtgccga gcatggcgca gaagatgtcc aaagtctgac ggcacaaagg
     4201 cgacgcgccg ctcaaagcct tttccgtgat ttcagacggc atcagtttgg cgggtttggc
     4261 tttctgtttt gcagccaaag cctcgtaaac caagctcaag cccgcgccgc tcaaaaagcg
     4321 ttcggcggaa acatggccgt atttgttttt ggcgtactgc caaatcagca cttccatatc
     4381 gtcaaacggc gggaaactgg tatgcccgcc ctcgcccgcc aaagccaccc agcctgcgtg
     4441 gctgtgcacc aatccgctca cgcccaggcc ggtaccgggg ccgataacgg ctttgggggc
     4501 aaattcgaca ggcttttgcc cgcctacctg catcaggtct ttgcttgaag tctgcgttac
     4561 cgccaatgcc tgcgcggtaa agtcgttcaa aaggatgagg gtgtccagcc ccaaagtctg
     4621 acgggtggtt tcgatggaaa acgcccaatg gtggttggtc atctgcaccc agtcgcccaa
     4681 aatcgggttg gcgatggcaa atgccgcgtg ccgtacggct gttgcaccgc tttgattcag
     4741 ataggcacgc accgcatcgg taaccgtatc gtagtcttta cacggaagca cggcggcttt
     4801 ttcaatgacg cgcggcgcgg tttccagcgc aaagcgtgca ttcgtcccgc cgatatcggc
     4861 gaccagtcgg ggatatccgg cttgtttatt cggcgtagaa gacatggcag ttcactcctt
     4921 gatggttcaa aacgaggttg atcggatatt cgcggttttc gccttgtgcg gcttggtcga
     4981 acacggcttt tttctcttcg ccccgtatcg ccaaaaacac atgccccgta tgggcaatcg
     5041 catccaaggt catactgacg cgctcgtgcg gcgcggtaac gggcgtggta tgcaccagcg
     5101 cgacacctgc cgaaccgtcg attgccgtct gaaactgcgg agctttcggg aaaatcgaag
     5161 ccgtatgccc gtcgtttccc atacccaaaa ccaaaacatc gggctgtttg taatgtttca
     5221 gtgcataatc gacaacagca tcgggatgta attcggtttc agtttttccg tcttccacca
     5281 taggaatcca cattgccgct tccgctttgt tcttcaacag gtattcgcgc accaaaccgg
     5341 tattgctgtc ggcgtggacg gtcggcacga tgcgttcatc tgccaaggtg atgccgacgt
     5401 ttttccaatc caaatctttt tgcgacaggg cgttgaaaaa tgcaatcggc gaacgtccgc
     5461 cggaaactgc caacaccgca ccgcccttct cgtccagtgc gccctgcaaa gcatccgcca
     5521 ctgcgtcagc caaagactgc gccgcttctg ccgcattttc gtattcgtgc caaacaaaca
     5581 tatttgtgtc ctttttttat ttcagacggc atattccgtt ttcgtattcg tgccaaacaa
     5641 acatatttgt gtcctttttt tatttcagac ggcatattcc gttatggaaa cgggttgagc
     5701 aatatgccgg tcgaacagtt gtttatgctt ttgataccaa atatcgggac tgctttttat
     5761 agtggattaa atttaaacca gtacagcgtt gcctcgcctt gccgtactat ttgtactgtc
     5821 tgcggcttcg tcgccttgtc ctgatttttg ttaatccact atactgcttt acttgcgttc
     5881 agacggcatt tcaaacccca tgccgtctga acgcattatt gtattactgc tcttcgtgcc
     5941 acttgtgtcc gtcgcgcgcc aatagttcgc gcgcggcttc aggcccccac gagtgtgcgc
     6001 cgtagccgtg cggcggcgtg gtgttatttg cccagttttc caaaatcggc atcacatatt
     6061 cccacgcggc ttcgagttcg tcgcggcggt tgaacaaagc gagtttgccg ttaatcacat
     6121 ccagcagcag gcgctcgtaa gcttccgcgc ggcggccttc caatgctttg cccaaatcgg
     6181 ttgccagcgg cacggtttcg accttatttc ctgcccccgg ggttttcatc tgcgtataga
     6241 ggcgcacgga ttcatatggt tgcaactcga taacgagccg gttgggcgcg gtgcgactgc
     6301 cttcaaaaat atggctgttc aaatctttga agttcaaaac gatttccgcc actttgcccg
     6361 ccatgcgctt gccggtacgc aggtagaagg gaacgccctt ccagcgttcg ttttcgattt
     6421 cggctttaat ggcgacgtag gtttcggtaa agctgtcttg cggaacgttg atttcttcaa
     6481 gatagccgtt catgcctttg gcggcggtat attgtccgcg cacgacattt tcattgacag
     6541 attcgacggt cagcggcttc aatgacttga tgactttgac tttttcatcg cgcaccgcgt
     6601 cggcatccaa gctggcgggg gcttccatcg cagtcatgca cagcatctgc atcaaatggt
     6661 tttgcaccat atcgcgcaac gcgccggtaa tgtcgtaaaa ctcgccgcgc tcttccacac
     6721 cgagctgttc ggcgatggtc aactgcacgc tttcgatgta tttattgttc cacagcggct
     6781 cgaacattac attggcaaaa cgcagcgcaa gcaggttttg caggctttct ttgccaaggt
     6841 agtggtcgat gcggtaaatt tgcccttctt tgaaataacg cgcaacatcg gtattgattt
     6901 gctgggaaga agccaaatcc gtacccaacg gtttttccaa aaccacacgc acgttgtcgg
     6961 cgttcaaacc gattttggca aggttttcac atgtttgcgc gaagaatttc ggcgcggtgg
     7021 aaagatagat gacgacattg tcggtttctt tgcgcgcttt gaccaaatcg cccaaagcgg
     7081 caaaatcgtc cggctgcgta acatcgactt tgagatatgc gagacgttcg acaaacgatg
     7141 cccaagcctc atcggaaaaa ttttctttca catggatttt ggaactggtt tccaccttcg
     7201 ccagaaaacc ttcggtatcc aactcgctgc ggctgacccc taaaatacgc ccttcgggat
     7261 gaagcagacc ggcaacatgc gcctggtaca gacagggcaa cagcttgcgc atcgccaaat
     7321 cgccggtcgc accgaacaac accaaatcaa aatttgtttg tgtactcatc gtattatctc
     7381 gtcaggaaag aatttttcga tgccgtctga aacctgtttc ccccatcacg ctgcatcgca
     7441 atatcggaaa caaaggcagg cggcataatg agtagtaata ctacacaccg ctacactttt
     7501 tgtctattcc catttttaca atttatttga cctagtccaa aaatcgggca ggtttcccct
     7561 attccgttac aacaatcgga agattctgcg atttaaatca aatttctttt cgatgtctga
     7621 tttttttgta acaaaattac aaattttgta ctataatagc acccgcttcc cactttcaga
     7681 cggcatacct tttaaaatat agtggattaa caaaaatcag gacaaggcga cgaagccgca
     7741 gacagtacag ataatacggc aaggcgaggc aacgccgtac tggtttttgt taatccacta
     7801 tactcaccgt ctgaataccc gatacaaaaa tcagaaacgc acaaacaaat ccccaatacc
     7861 ccccgttccg acaggagacc gaccgtgaac actactccta tccactccaa actcgccgaa
     7921 atcaccgggc gcattattga acgcagccgt ccgacgcgtg aaaaatatct ggcgaagatc
     7981 cgcagtgcca aacaaatggg acgcttagag cgcaaccagc tcggttgctc caacttggcg
     8041 cacggctatg ctgccatgcc taaaagtatc aaaatcgaaa tgcttcagga aaccgtcccc
     8101 aacttaggca tcatcaccgc ctacaacgac atggtttccg cacaccagcc gtttaaagac
     8161 ttccctgacc aaatcaaaga cgaagcgcag aaaaacggcg cgaccgccca agtcgccggc
     8221 ggcacacccg ccatgtgcga cggcatcacg caaggctacg ccggtatgga actgtcgctg
     8281 ttctcccgcg acgtgattgc catgagtacc gccgtcgggc tgtcgcatca aatgtttgac
     8341 ggcagcctgt ttatgggcgt atgcgacaaa atcgttccgg gtttgatgat aggcgcgctt
     8401 tcgttcggtc atattccggg tatcttcgtc cccgcaggcc cgatgtccag cggtatcggc
     8461 aacaaagaaa aagcccgcac ccgccagctt ttcgccgaag gcaaggtcgg acgcaacgaa
     8521 cttttgaaaa gcgaaatggg ttcttaccac agcccgggca cctgcacttt ctacggcacg
     8581 gcaaactcca accaaatgat gatggaaatg atgggcgtgc acctgcctgc cgccgccttc
     8641 gtccaccctt acaccgacct gcgcgaagcc ctaacccgct acgccgccgg acacctcgcg
     8701 cgcggcatca aaaacggcac gattaaacct ttgggcgaaa tgttgaccga aaaatccttt
     8761 atcaacgcct tgattggcct gatggcaacc ggcggttcga ccaaccacac catgcacctc
     8821 gttgccatgg cacgcgccgc cggcgtgatt ttgaactggg acgacttcga cgaaatttcc
     8881 tccatcatcc cgctgctcat tcgcgtttat ccgaacggca aggccgacgt gaaccacttt
     8941 accgcagcgg gcggactgcc tttcgttatc cgcgaattgc tgaatgcagg cctgttgcac
     9001 gacgatgtcg ataccgtcgt cggacacggt atgcgccact acaccaaaga gcctttcctc
     9061 atcgacggca aactcgaatg gcgcgaagcc cccgaaacca gcggcaacga cgacatcctg
     9121 cgtaaagctg acaacccgtt ctcccccgac ggcggtctgc gcctgatgaa aggcaacatc
     9181 ggacgtggcg tgattaaagt gtccgccgtg cgcgaaggct gccgcattat tgaagcgcct
     9241 gccatcgtgt tcaacgacca acgcgaagtg ttggctgcgt ttgaacgcgg cgagttggaa
     9301 cgcgattttg tgtgcgtcgt ccgctaccaa ggcccgcgtg ccaacggtat gcccgaattg
     9361 cacaaactga ccccgccttt aggcatcctg caagaccgcg gcttcaaagt ggcgctgctg
     9421 accgacggcc gtatgtccgg cgcgtccggc aaagttccag cctccatcca catgacaccc
     9481 gaagccctga tgggcggcaa catcgccaaa atccgtaccg gcgacctgat ccgcttcgac
     9541 tccgttaccg gcgaactcaa cgtcctgatt aacgaagccg aatggaacgc ccgagaagtc
     9601 gaaagcatcg acttgggcgc gaaccaacaa ggctgcggcc gcgaactttt cgccaacttc
     9661 cgcagcatga ccagcagcgc cgaaaccggc gcgatgagct tcggcggcga atttgcctga
     9721 tgcgcgtttc agacggcctt ttcagaccga aggccgtctg aaaaattatt caagtgtttt
     9781 aagatagacg taggtcggat tctcgaatcc gacacagccg tccaagatgt cggtttcttg
     9841 aatccgacct acaacctgtc ccatcttaat aaaatacccc atcccacccg gagaaccgaa
     9901 atgtccaaac tgaccccccg cgaaatcctg accgccggcg cagttgtacc ggtaatggcg
     9961 attgacgact tgagtactgc cgtcgatttg tcccacgccc ttgtcgaagg cggcatcccc
    10021 accctcgaaa tcaccctgcg cacccctgtc ggcctcgatg ccatccgcct gattgccaaa
    10081 gaagtgccca acgccatcgt cggcgcgggt acggttacca accctgaaca gctcaaagcc
    10141 gtcgaagacg caggcgcggt tttcgccatc agcccgggtt tgcacgaatc cctcgccaaa
    10201 gccggccaca acagcggcat ccccctgatt cccggtgttg ccaccccggg cgaaatccaa
    10261 ctggctttgg aacacggcat cgacaccctc aaactcttcc ctgccgaagt cgttggcggc
    10321 aaagccatgc tcaaagccct gtacggccct tacgccgatg ttcgcttctg cccgacaggc
    10381 ggcatcagcc tcgccaccgc gcccgattac ttggcactgc ccaacgtcct gtgcgtcggc
    10441 ggctcatggc tgacgccgaa agaagccgtg aaaaacaaag actgggacac catcacccgt
    10501 ctcgccaaag aagcggcggc attgaaaccc aaagcctgaa ccgcatcgta aaaatgccgt
    10561 ctgaagccct ttccagtctc agacggcatt ttgccgcttg gcggcgcagt cggcatacac
    10621 ggcagcacca ctccgacata ctgcccctaa aatgcccatc cgccttccgc ataataaaaa
    10681 taacgttcag ttcattcgac agcagccgga cagcccatac tacgcggctg aaaaaatgcc
    10741 gtctgaaacg cattcagacg gcatccgctt aaaaaaacaa ctgattcaag gccgattaat
    10801 ccgcttccaa aaccactttc atcgcttgat tttcggcggc gtgtttgaac acgtcgtagg
    10861 ctttttccaa ttcgctgaat ttgaaacggt gggtcaacat tttggtgtaa tcgacggagc
    10921 tgctggaaat tgccttcatc agcatttcgg tggtattggc gtttaccagg ccggtagtga
    10981 tggcaagctt tttaatccac agtttttcca gtttgaaatc aacggattga ccgtgtacgc
    11041 cgacaacggc gatatggccg ccgggtttca caatgtcttg gcacatattc caagttgcag
    11101 ggataccgac ggcttcgatc gcgcagtcca cgccgtcttc gccgacgata gcgacaactt
    11161 gcttgcttac atcgccggaa gcagggttaa tggtatgggt tgcgcccaac tctttcgcca
    11221 gtttcaaacg gttttcgtcc atatcgcaaa caatgatggc ggcggggctg tacagttggg
    11281 cggtcggcaa ggcgtcgctc aacaacaggg cgacttcttc gttgacgttg tcgggcagcg
    11341 gcacgaggct gttgtcggca taaggcgtgc ggacgtattc tgcctgcgtg ccgtcaatca
    11401 tgtagcccaa aatccagccg ccgttgcggc aatgcgaata aagttggatt ttgcagttgt
    11461 cgcaagtaca gcatttgctg acgcatgaaa taatgacttt atcgccgact ttgatgtttt
    11521 ttacagcctc gccgacttct tctacaatac cgatgccttc atgaccgaga atacggccgt
    11581 cggcgacttc gggttttttt gcctttccaa atacccaaat cggtaccgca aatcgtggtt
    11641 ttgacgattt tcaccaccgc atcggtcgga tcgataatct gcggacgggg tttttcttca
    11701 aaacggatgt cgtttgcgcc gtgataaacc attgctttca tgctgatact ccttgcttgt
    11761 tgataaataa tttcaatacc gcaataaagt ttccttatat gagttatatg cccctacaaa
    11821 aaataagtca ataagaatta ttttcacaat gttatacaat aacatactat tttaaatata
    11881 aataaaacca ccgattgata ttaatgaaca cacccatccc cttctccgaa cggctcatcc
    11941 gctggcaaaa acaacacggt cgccaccacc tcccttggca ggtcaaaaac ccttattgcg
    12001 tctggctttc cgaaatcatg ctccagcaaa cgcaagtcgc caccgtgttg gactactatc
    12061 cgcgcttctt agaaaaattc ccgaccgttc agacgcttgc cgccgcgccg caagacgaag
    12121 tgttgtcgtt gtgggcgggc ttgggctatt acagccgcgc gcgcaacctg cacaaagccg
    12181 cgcaacaagt cgtcaggcaa ttcggcggca cgtttccgtc ggagcgcaaa gacttggaaa
    12241 ccctctgcgg cgtaggcaga agcaccgccg ccgccatttc tgccttctcc ttcaaccgcc
    12301 gcgaaaccat tttggacggc aacgtcaaac gcgtactctg ccgcgtgttc gcccgcgacg
    12361 gcaatccgca ggacaaaaaa tttgaaaact cgctctggac acttgccgaa agcctgctgc
    12421 cgtctgaaaa cgccgatatg cctgcctata cacaaggttt gatggatttg ggcgcgaccg
    12481 tgtgcaaacg gacgaaaccc ttgtgccacc aatgcccgat ggcggacatc tgcgaagcaa
    12541 aaaagcaaaa ccgcaccgcc gagctgccgc gcaaaaaaac cgccgccgaa gtaccgaccc
    12601 tgccgcttta ctggctgatt gtccgcaacc gggacggcgc gattttgctg gaaaaacgcc
    12661 ccgccaaagg catttggggc gggctgtatt gcgtgccgtg ttttgaaagt ttgaacgggc
    12721 tttccgactt tgccgccaaa ttctccctga ccatggcaga tatggacgaa caaaccgccc
    12781 tgacccaccg tctgacgcac cggctgctga tgattacgcc gtttgaagga caaatgccgt
    12841 ctgaaagccc ttcagacggc atttggataa agccggcgca tttgaaagat tacggcctgc
    12901 ccaagccttt ggaaatttat ttaaacggta ataggttaga ataaacaaaa taaacccatt
    12961 gaactgttgt ttgcaggtat cgcagcaaga acaaccgatg aatttgggtc gtattttagg
    13021 cggtgggata atgttcaaat gggacatttg gaacggaaga agtcggcaat ttaaaaagga
    13081 tttaaaaagc aaagaaggtc aaaaacatga acacaaactt aaatgacaaa gacaaagcca
    13141 tggataccgc aatcaggttt cagaaaagga tgaggattcc gaaatttttc tttttaattc
    13201 tctgaatcac aatggttttg gcatttatcc aagacgtgat aacgggttct aattttctgc
    13261 aaataacaat taatgtaaaa ttttcgtaaa aatttatcgg cttttaaaac aaaattgact
    13321 aaaatagtcg cgagttttta ctgcaataaa ggagattgca atgaatatga aaaccttatt
    13381 agcactagcg gttagtgcag tatgttcagt tggtgttgcg caagcacacg agcataatac
    13441 gatacctaaa ggtgcttcta ttgaagtgaa agtgcaacaa cttgatccag caaacggtaa
    13501 caaagatgtg ggtacagtga ctattactga atctaactat ggtcttgtgt ttacccctga
    13561 tttacaagga ttaagcgaag gcttacatgg tttccacatc catgaaaacc caagctgtga
    13621 gccaaaagaa aaagaaggta aattgacagc tggtttaggc gcaggcggtc actgggatcc
    13681 taaaggtgca aaacaacatg gttacccatg gcaagatgat gcacacttag gtgatttacc
    13741 tgcattaact gtattgcatg atggcacagc aacaaatcct gttttagcac cacgtcttaa
    13801 acatttagat gatgttcgcg gtcactctat tatgatccac acgggtggtg ataatcactc
    13861 cgatcatcca gctccacttg gcggtggcgg cccacgtatg gcatgtggcg tgattaaata
    13921 attcgattgt tcgaaacgaa aagtgcggtg aattttgacc gcactttttt gctagatatt
    13981 tagcatttaa ttcacgactt cagcagtata gtgaattaaa tttaaaccag tacagcgttg
    14041 cctcgcctta gctcaaagag aacgattctc taaggtgctg aagcaccaag tgaatcgatt
    14101 ccgtactatt tgagaccttt gcaaaattcc cttccctccc gacagccgaa acccaaacac
    14161 aggttttcgg ctgttttcgc cccaaatacc tcctaattct acccaaatac ccccttaatc
    14221 ctccccggat acccgataat caggcatccg ggctgccttt taggcggcag cgggcgcact
    14281 tagcctgttg gccgctttca acaggttcaa acacatcgcc ttcagatggc tttgcgcact
    14341 cactttaatc agtccgaaat aggccgcccg cgcatagcgg aatttgcggt gtaac
//
LOCUS       DAXISH010000054        14317 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.054, whole genome shotgun sequence.
ACCESSION   DAXISH010000054 DAXISH010000000
VERSION     DAXISH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 14317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14317
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.054"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..212)
                     /locus_tag="ACFOV4_001617"
     CDS             complement(<1..212)
                     /locus_tag="ACFOV4_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC7619588.1"
                     /translation="MSTFFQQTAQAMIAKHINRFPLLKLDQVIDWQPIEQYLNRQKTR
                     YLRDHRGRPAYPLLSMFKAVLLGQWH"
     gene            399..581
                     /locus_tag="ACFOV4_001618"
     CDS             399..581
                     /locus_tag="ACFOV4_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619589.1"
                     /translation="MFWYVIGFCSFVVALLSLWVNVGAFGMQEDDTPQSDYERRLGLG
                     AKLKNKNTPKSGEKRQ"
     gene            complement(630..1631)
                     /locus_tag="ACFOV4_001619"
     CDS             complement(630..1631)
                     /locus_tag="ACFOV4_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFC7619590.1"
                     /translation="MIDGQTNKPKQKTRIILAPMQGLVDDVMRDLLTRIGGYDECVSE
                     FVRITHTVHSRSIWLKYVPEIANGNKTFSGTPCTVQLLGSDADNMAANALEAVRFGAN
                     KIDLNFGCPAPTVNKHKGGAILLKEPELIFHIVKTLRGRLPAHIPLTAKMRLGYEDKS
                     RALECACAIAEGGACGLTVHARTKAEGYEPPAHWEWIRKIRDSVNIPVTANGDVFSLQ
                     DYIGIKTISGCNSVMLGRGAVIRPDLARQIKQYESGLPVTDTDFAEISRWIRLFFDLC
                     LAKGANNKYPIARLKQWLGMMKKTSGPAQTLFDRVRTVKDADEVRRILSASEYEMNV"
     gene            complement(1708..5541)
                     /locus_tag="ACFOV4_001620"
     CDS             complement(1708..5541)
                     /locus_tag="ACFOV4_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3683 domain-containing protein"
                     /protein_id="HFC7619591.1"
                     /translation="MTTTTAPQRIREIPYNYTSYTDREIVIRLLGDEAWQILQDLRGQ
                     RKTGRSARMLFEVLGDIWVVVRNPYLVDDLLEHPKRRAALIREMRHRLNEIRKRRDDN
                     RQVDVLVAAAEKAVERFDSSFDETSQKRRQILERLSKITKPHNIMFDGLARVTHVTDA
                     TDWRVEYPFVVVNPDTEAEIAPLVRALIELDLVIIPRGGGTGYTGGAIPLDANSAVIN
                     TEKLDKHRGVEYVELAGLDGKHPIIRCGAGVVTRRVEETAHQAGLVFAVDPTSADASC
                     VGGNVAMNAGGKKAVLWGTALDNLAYWQMVNPQGEWLRIERVRHNFGKIHDEETAVFD
                     VHTLDSDGLNIVKTERLEIPGHKFRKVGLGKDVTDKFLSGLPGVQKEGTDGIITGVAF
                     VLHKMPKYTRTVCMEFFGTVATATPSIVEIRDFLLAHDSVRLAGLEHLDWRYVRAVGY
                     ATKAAGKGRPKMVLLADVVSDDEAAVEAAAEHICELARARDGEGFIAVSPEARKTFWL
                     DRSRTAAIAKHTNAFKINEDVVIPLERLGEYSDGIERINIELSIQNKLKLCAALEQYL
                     SGKLPIDKMGTDLPTAELLGERGKHALAHVSAVKARWEWLLANLDAPLADYKVRYGSA
                     VHAAPEAKDNESCFTAFRDFRLRVSVKADVMKPLSEIFSGKTDTKIIQGLGKIHAKTV
                     RSRVFVALHMHAGDGNVHTNIPVNSDDAEMLQTAYRSVERIMKIARSLGGVISGEHGI
                     GITKLEFLSDEEMQPFWDYKNQVDPKHTFNRHKLMKGSDLRNAYTPSFELLGAESLIM
                     EKSDLGTIADSVKDCLRCGKCKPVCSTHVPRANLLYSPRNKILGVGLLTEAFLYEEQT
                     RRGVSIKHFEELMDIGDHCTVCHRCVKPCPVNIDFGDVTVAVRNYLADSGHKRFAPAA
                     AMGMAFLNATGPKTIKALRAAMIQTGFPAQNFAYKIGKLLPIGTKKQKAEPKATVGTA
                     SIKEQVIHFINRPLPKSVPAKTPRSLLGIEDGKSIPIIRNPASPEDAEAVFYFPGCGS
                     ERLFSQIGLAVQAMLWHVGVQTVLPPGYMCCGYPQDAGGNKAKAEEMSTNNRVAFHRM
                     ANTLNYLDIKTVVVSCGTCYDQLEKYRFEEIFPGCRIIDIHEYLLEKGVKLNGVKGQQ
                     YLYHDPCHTPIKTMNATQMASSLMGQKVVLSDRCCGESGMFAVKRPDIATQVKFRKQE
                     EIEKNLKELPQGEPVKMLTSCPACLQGLSRYADDNNMPADYIVIEMAKHILGENWLDE
                     FVKKANNGGVEKVLL"
     gene            5802..5898
                     /gene="ffs"
                     /locus_tag="ACFOV4_001621"
     ncRNA           5802..5898
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACFOV4_001621"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            6066..7757
                     /gene="dld"
                     /locus_tag="ACFOV4_001622"
     CDS             6066..7757
                     /gene="dld"
                     /locus_tag="ACFOV4_001622"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016901 - oxidoreductase activity, acting
                     on the CH-OH group of donors, quinone or similar compound
                     as acceptor [Evidence IEA];
                     GO_process: GO:0006089 - lactate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HFC7619592.1"
                     /translation="MSASQLLSRLTQTVGEKYIITDPAKTEQYRQGYRFGEGKALAVV
                     RPGSILEMWKILQACVEADVIVITQAANTGLTGGSTPDGNDYDRDIVIVNTMRMNIIQ
                     TINNNEQVVCLPGSTLNQLELLLKPLGREPHSVIGSSCIGASVLGGVCNNSGGALVQR
                     GPAYTEMALFAQINEEGRLELVNHLGIDLGDTPEEILTNLQGHHYQNKDIKQDAGKGH
                     DHAYCEHVRQVDEPTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQEKQTAVFYIG
                     TNDINELTDIRRAALGEFESLPVSGEYIHRHAFDIADVYGKDTFYVIKKFGTHQLPKL
                     FDLKARVDRFGKKASFLPKHFSDKAMQFVSKYLPDHLPKSMRDYRDKYEHHLILKMGG
                     KGVDEARAFLKEYFAHHSGAFFECNAEETQAAMLHRFAVASAAIRYRAVHDDEVEDLV
                     ALDIALRRDDRDWFEKLPPEIDNKIIHKLYYGHFMCHVFHQDYIIKKGNDCMALEHEM
                     LHLLDQRGAQYPAEHNVGHLYEAKPALKQFYRKLDPTNSFNPGIGKTSKKKNWAE"
     gene            7889..7996
                     /locus_tag="ACFOV4_001623"
                     /pseudo
     CDS             7889..7996
                     /locus_tag="ACFOV4_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            8052..8423
                     /locus_tag="ACFOV4_001624"
     CDS             8052..8423
                     /locus_tag="ACFOV4_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HFC7619593.1"
                     /translation="MKPYKIYTHPALPPQAVKQGWSWPGLLFGTLWACFKRMWGLGLG
                     LTGAIFVLAVFAQLVYGDTPATDSAFNVLGLAVSVWFGAKGNSLYARHLLSRGYTELP
                     ETVEAANPQAALAQYFGRGGR"
     gene            8578..9126
                     /locus_tag="ACFOV4_001625"
     CDS             8578..9126
                     /locus_tag="ACFOV4_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFC7619594.1"
                     /translation="MARLTVHTLETAPEAAKARVEAVLQNNGFIPNLIGVLSNAPEAL
                     AFYQEVGKLNAANSLTAGEVEVIQIIAARTNQCGFCVAGHTKLATLKKLLSEQSVKAA
                     RALAAGEFDDAKLGALAAFTQAVMAKKGAVSDEELKAFFDAGYNQQQAVEVVMGVALA
                     TLCNYVNNLGQTEINPELQAYA"
     gene            9260..10351
                     /locus_tag="ACFOV4_001626"
     CDS             9260..10351
                     /locus_tag="ACFOV4_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HFC7619595.1"
                     /translation="MNAQTLIANVAEFVKTKLKPIVDDIDRKGYYPEAFMRELGAIGG
                     FGAVGTEAEGGNGLGLATQIAVLREIGKECGATSFSAWCQAACAWYLHQTPNRAVKDK
                     YLADILQGKVLAGTGMSNTVKHLADIEKHNLQAERVEGGYTVNGALPWVSNIGEDHIW
                     ANTAQIGGGYVMFITGGQWEGVSLQNCPEFCALEGTRTFSLNFKDVFIPDEDIIAAPE
                     QFADYIQSIKAGFILLQIGIGAGVIDGSLGIIRLANVVNAEVNRYLDDGYDSLKTRLD
                     GAWAETERLAGLAWSGTPDNLTTLKLREAAAVLTLAAAQSAALHSGAKGYLMRSPAQR
                     RVREAMFVAIVTPAIKHLRKEIAAIEAAK"
     gene            10870..11430
                     /locus_tag="ACFOV4_001627"
     CDS             10870..11430
                     /locus_tag="ACFOV4_001627"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619596.1"
                     /translation="MIESIEKPQESIRKNRNPHRVIPAQAGIQKRNATGIYRKKQKPP
                     PRHSRAGGNPETQRGRTLSEKTETLTTVIPAQAGIQKRNATGIYQKKQKPHRPSFPRR
                     RESRNTTRQDFIGKNRNPTDRHSRKSGNPATEKPQESISKNRNPTAVIPAKAGIQTRR
                     HGNLPNKTVSLDSTSQIPAFAGMTRF"
     gene            11542..13344
                     /locus_tag="ACFOV4_001628"
     CDS             11542..13344
                     /locus_tag="ACFOV4_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ESPR-type extended signal peptide-containing
                     protein"
                     /protein_id="HFC7619597.1"
                     /translation="MNKIYRIIWNSALNAWVVVSELTRNHTKRASATVATAVLATLLS
                     ATVQANATDEEDDEELEPVVRTAPVLSFHSDKEGTGEKEEVGASSNLTVYFDKKGVLK
                     AGTITLKAGDNLKIKQNTNENNNENTNASSFTYSLKKDLTDLTSVGTEKLSFSANGNK
                     VNITSDTKGLNFAKETAGTNGDTTVHLNGIGSTLTDTLLNTGATTNVTNDNVTDDEKK
                     RAASVKDVLNAGWNIKGVKPGTTASDNVDFVRTYDTVEFLSADTKTTTVNVESKDNGK
                     KTEVKIGAKTSVIKEKDGKLVTGKDKGENGSSTDEGEGLVTAKEVIDAVNKAGWRMKT
                     TTANGQTGQADKFETVTSGTKVTFASGNGTTATVSKDDQGNITVKYDVNVGDALNVNQ
                     LQNSGWNLDSKAVAGSSGKVISGNVSPSKGKMDETININAGNNIEITRNGKNIDIATS
                     MTPQFSSVSLGAGADAPTLSVDDEGALNVGSKDANKPVRITNVAPGVKEGDVTNVAQL
                     KGVAQNLNNRIDNVDGNARAGIAQAIATAGLAQAYLPGKSMMAIGGGTYRGEAGYAIG
                     YSSISDTGNWVIKGTASGNSRGHFGTSASVGYQW"
     gene            13477..>14317
                     /locus_tag="ACFOV4_001629"
     CDS             13477..>14317
                     /locus_tag="ACFOV4_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFC7619598.1"
                     /translation="MSTFFQQTAQAMIAKHIDRFPLLKLDQVIDWQPIEQYLNRQKNR
                     YLRDHRGRPAYPLLSMFKAVLLGQWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYS
                     TLCRYRNWLAQDDTLSELLELINRQLTEKGLKVEKASAAVVDATIIQTAGSKQRQAIE
                     VDEEGQINGQTTPSKDKDARWIKKNGLYKLGYKQHTRTDAEGYIEKLHITPANAHECK
                     HLSPLLEGLPKGTTVYADKGYDSAENRQHLKEHQLLDGIMRKACRNRPLTEAQTKRNR
                     YLSK"
BASE COUNT         3609 a         3879 c         3764 g         3065 t
ORIGIN      
        1 ctgtgccatt gtccgagcag gacggctttg aacatggaca gcaggggata ggcaggacgg
       61 ccgcggtggt ctcgaaggta acgggttttt tgacgattca ggtattgttc gatcggctgc
      121 caatcaatca cctggtccaa cttcaatagc gggaagcggt tgatgtgttt ggcaatcatg
      181 gcttgggcgg tttgctggaa gaaggtgctc atgagaaatc ccctaaatgt cttggtggga
      241 atttagggga ttttggggaa ttttgcaaag gtctctattt gtactgtctt cggctcgccg
      301 ccttgtcctt atttaaattt aattcactat atttgcccgt gcatttgtga taaattcggc
      361 actgtatttg atatgatttt aacaaatcgg gaggggcaat gttttggtat gtaatcggct
      421 tttgctcctt tgtcgtcgcg ctgctgtcgc tgtgggtcaa tgtcggcgca ttcggtatgc
      481 aggaagacga taccccgcaa tcggattatg aaaggcgttt gggtttgggg gcgaaactga
      541 aaaacaaaaa tacgccgaaa tcaggggaaa aacggcaata aagacagcaa atgctttcag
      601 ccggcatttg ctttgaagta tgggagacat caaacattca tctcatactc ggacgcgctc
      661 aggattcggc ggacttcatc cgcatcctta accgttcgga cgcggtcaaa cagcgtttgc
      721 gccgggccgg acgttttttt catcatgccc agccattgct taaggcgggc aatcggatat
      781 ttgttgtttg ccccttttgc caggcataaa tcgaaaaaga gccgtatcca tctggaaatt
      841 tcggcaaaat cggtatccgt aacgggcagg ccgctttcat actgcttgat ttgccgcgcc
      901 aaatcggggc ggatgaccgc gccgcgaccg agcatcacgc tgttgcagcc gctgattgtt
      961 ttgatgccga tatagtcttg caggctgaaa acgtcgccgt tggcggtaac gggaatattg
     1021 acgctgtctc ggattttcct tatccattcc caatgcgccg gcggttcgta accctcggct
     1081 ttggtacgcg cgtgtacggt cagtccgcat gcgccccctt cggcaatcgc acaggcgcat
     1141 tccaaagccc ggcttttgtc ttcgtaaccg agccgcattt ttgcggtgag cggaatatgt
     1201 gcgggcaaac gtccgcgcag cgttttgacg atgtggaata tcagttccgg ctcttttaaa
     1261 aggattgcgc cgcctttgtg tttgttgacg gtgggcgcgg ggcagccgaa gttcaaatcg
     1321 attttgttcg caccgaagcg gacggcttcc agcgcattcg ccgccatatt gtccgcatcg
     1381 ctgcccaaaa gttggacggt gcagggcgtg ccggaaaacg ttttgtttcc gttggcgatt
     1441 tcggggacat attttaacca tatggatcgg gaatgcacgg tatgggtaat gcgtacaaat
     1501 tcgctgacgc attcgtcgta gccgccaata cgcgtcagca ggtcgcgcat cacgtcatcg
     1561 accagaccct gcataggggc aaggatgatt cgggtttttt gtttgggttt gtttgtttgt
     1621 ccgtcaatca tgatttgggt aggtatttga ttcaaacaat gccgtctgaa ggctttcggc
     1681 gttcagacgg catttccgtg tccgttgtta cagcaatact ttttccacgc cgccgttgtt
     1741 ggcttttttg acgaactcgt ccagccagtt ttcgccgaga atgtgtttcg ccatttcaat
     1801 gacgatgtag tcggcaggca tattgttgtc gtcggcgtag cggctcaaac cttgcaggca
     1861 ggcggggcag gaagtcagca ttttgacggg ttcgccctgc ggcagctctt tgaggttttt
     1921 ctcgatttcc tcttgtttgc ggaacttgac ctgagtggcg atgtctggtc gtttgacggc
     1981 aaacataccg gattcgccgc agcagcggtc gcttaaaaca actttctgcc ccatcaggct
     2041 gctggccatt tgggtggcgt tcatggtttt gatgggcgtg tgacaggggt cgtggtagag
     2101 gtattgctga cctttcacgc cgtttagttt cacgcctttt tcaagcaggt attcgtggat
     2161 gtcgatgatg cggcagccgg ggaagatttc ctcgaagcgg tatttttcga gctggtcata
     2221 acaagtgccg caactgacga cgacggtttt gatgtcgagg tagttgaggg tgttcgccat
     2281 acggtggaaa gccacgcggt tgttggtgct catttcttcg gcttttgcct tattgccgcc
     2341 cgcgtcttgc ggatagccgc aacacatata gcccggcggc aggacggttt gtacgccgac
     2401 gtgccagagc atagcttgga cggcaagccc gatttggctg aacaggcgtt ccgaaccgca
     2461 accggggaag tagaacacgg cttcggcatc ttccggagaa gccggattac ggatgatggg
     2521 gatgcttttg ccgtcttcga tgcccaataa ggagcgcggt gttttggcgg gtacgctttt
     2581 gggcagtggg cggttgatga aatggataac ctgttctttg attgaggcgg taccgacggt
     2641 tgccttgggt tcggcttttt gctttttcgt gccgattgga agaagtttgc cgattttgta
     2701 ggcaaagttt tgcgcgggga agccggtttg tatcatggcg gcgcgaaggg ctttgatggt
     2761 tttcgggccg gtggcgttca aaaacgccat acccatagct gcggcaggcg caaatcgttt
     2821 gtggccggaa tcggcaaggt agttgcggac ggctacggtt acgtcgccga agtcgatgtt
     2881 gacggggcag ggtttgacgc agcggtggca cacggtgcag tggtcgccga tgtccatgag
     2941 ttcttcaaag tgtttgatgg aaacgccgcg acgggtttgt tcttcgtata agaaggcctc
     3001 ggtcagcaaa cccacgccga ggattttgtt gcgggggctg tacagcaggt tggcacgcgg
     3061 aacgtgggtg gagcagacgg gtttgcattt gccgcagcgc aggcagtctt tgacggaatc
     3121 ggcaatcgtg ccgaggtctg atttttccat aatcagcgat tccgcgccca aaagctcgaa
     3181 agacggcgtg taggcgttgc gtaagtccga gcctttcatc agtttgtgac ggttgaaggt
     3241 gtgtttggga tcgacttggt ttttgtagtc ccaaaacggc tgcatttctt cgtcgcttaa
     3301 aaattcgagc ttggtgatgc cgatgccgtg ttcgcccgaa atcacgcctc cgagcgaacg
     3361 ggcgattttc ataatgcgtt cgactgagcg gtatgccgtc tgaagcattt cggcatcgtc
     3421 tgagttaacc ggaatattgg tgtgaacgtt accgtcgccg gcgtgcatat gcagggcgac
     3481 aaagacgcgg ctgcgtacgg tttttgcgtg gatttttccc aagccttgga taattttggt
     3541 gtcggttttg ccgctgaaga tttcagaaag cggcttcatt acgtccgctt tgacagacac
     3601 gcgcaggcgg aaatcgcgga atgcggtaaa gcagctttca ttgtctttgg cttcgggcgc
     3661 ggcgtggacg gctgagccat agcgtacttt atagtcggca agcggcgcgt ctaagttagc
     3721 aagcagccat tcccaacgcg ctttgacggc ggaaacgtgg gcaagggcgt gtttgccgcg
     3781 ttcgcccaaa agttcggcgg tcggcaggtc ggttcccatt ttgtcgatgg ggagtttgcc
     3841 ggacagatat tgttccaagg cggcacagag tttgagtttg ttttggatgg aaagctcaat
     3901 gttaatgcgt tcgatgccgt ctgaatactc accgagcctt tcgagtggga tgaccacgtc
     3961 ttcgttaatt ttaaaggcgt tggtgtgttt ggcgatggcg gcggtgcggc tgcggtcgag
     4021 ccagaaggtt ttgcgcgctt cgggcgatac ggcgataaag ccttcgccgt cgcgggcgcg
     4081 ggcaagttca cagatgtgct cggcggctgc ctctacggcg gcttcgtcgt ctgaaaccac
     4141 gtccgccagt aagaccattt tcggccggcc tttgcctgcc gctttggtgg cgtagccgac
     4201 ggcgcggaca taacgccagt ccaaatgttc caaacctgcc agccgaacgc tgtcgtgggc
     4261 gagcaggaaa tcgcggattt cgacgataga aggcgtagcg gtggcgaccg tgccgaaaaa
     4321 ctccatacac acagtgcgcg tgtatttcgg cattttgtgc aacacgaaag caacgccggt
     4381 gatgatgccg tccgtgcctt ctttctgtac gccgggcagg ccgctcaaga atttgtcggt
     4441 aacgtctttg cccaaaccga ctttgcgaaa tttgtggccg ggaatttcca aacgttcggt
     4501 tttaacgata ttgaggccgt ctgaatccag cgtgtgaacg tcgaacacgg cggtttcttc
     4561 gtcgtggatt ttgccgaaat tgtggcgcac gcgctcgatg cgcagccatt cgccctgcgg
     4621 gttgaccatc tgccagtagg cgaggttgtc caacgccgtc ccccacagca cggctttttt
     4681 accgcccgcg ttcatcgcca cattaccgcc cacacaggac gcatcggcgg aagtcggatc
     4741 gacggcgaac accaaacctg cctgatgcgc ggtttcttcc acccgccgcg taaccacgcc
     4801 cgcgccgcac cggataatcg gatgcttgcc gtccaagcct gccagctcaa cgtattcaac
     4861 accacgatgc ttgtcgagtt tttcggtatt gatgactgcg ctgtttgcgt ccaaaggaat
     4921 cgcgccgccg gtataacccg tgccgccgcc gcgcggaata atgaccaaat ccagctcgat
     4981 taaggcgcgc accaaaggcg cgatttccgc ctccgtgtcg ggattgacga cgacaaacgg
     5041 atactccacg cgccagtcgg ttgcatcggt aacgtgcgtt acccgcgcca atccgtcaaa
     5101 cataatattg tgcggcttgg tgattttgct caaacgctcc aaaatctgcc gccgcttttg
     5161 gctggtttca tcaaaactgc tatcaaaacg ctcgactgct ttttctgctg cggcaaccaa
     5221 gacatccact tgccgattat cgtcgcggcg tttgcggatt tcgttcaggc ggtggcgcat
     5281 ttcgcgtatc aacgcggcgc ggcgtttcgg atgctccagc aaatcatcga ccagatacgg
     5341 attgcgcacg accacccaaa tatcgcccaa cacttcaaac agcatccgcg ccgaacgtcc
     5401 agttttacgc tgtccgcgca agtcttgcag aatctgccac gcctcgtcgc ccaataatcg
     5461 gatgacgatt tcgcggtcgg tgtaggaagt atagttgtag gggatttccc gaatacgctg
     5521 aggggcggta gtcgtggtca tggtgtgtcc gtgtttggca gtttttattt gaatgccgtc
     5581 tgaaaagtcg gtttcaggcg agtttgaaaa ggcgataatg tagttcaatt tttgatactt
     5641 ttcaatgccg aaacaggaaa tacccttata gaaacaaaat aacgctttga gaaattgttg
     5701 acaatattat caaatataaa ttttaggtgg tgtttccggc gtatgaccgt atcaaaacgg
     5761 ttgagttttt cagaaaaccc gttataatgc cgtttctctg aggcgggtct ccccgcatgg
     5821 caaatcggaa caccgggtca ggggcggaag ccagcagccc actccgatgc gccagtgccg
     5881 ggggtttggc ccgccgccct atttgaaacg ccggagcttc gatgttccgg cgttcccgta
     5941 tcgcaccgat gccgtctgaa agccgttcag acggcatttc ctttactttg ccataacgca
     6001 taactacaat gggaaaacaa tttcaatgtg catatgcacc tgccgacaat tttaaggaaa
     6061 ctgccatgag cgcatcacaa ttactgtcaa gactgaccca aaccgtaggc gaaaaataca
     6121 tcatcaccga ccccgcgaaa accgaacaat accgccaagg ctaccgcttc ggcgagggta
     6181 aggcgttggc ggtggttcgc cccggaagca ttctggaaat gtggaaaatt ctgcaggcct
     6241 gcgtcgaagc ggacgtgatt gtgattacgc aggcggcgaa taccggtttg acgggcggct
     6301 cgacccccga cggcaacgat tacgaccgcg acatcgtgat tgtgaacacc atgcggatga
     6361 acatcatcca aaccatcaac aacaacgaac aagtcgtctg cctgcccggt tcgaccctga
     6421 accagcttga attgctgctg aaacctttgg ggcgcgaacc gcattcggtc atcggctcat
     6481 cctgtatcgg tgcgtccgtc ttgggcggcg tgtgcaacaa ctccggcggc gcgttggtac
     6541 agcgcggccc ggcctacacc gaaatggcgt tgttcgccca aatcaacgaa gaaggcaggt
     6601 tggaactggt caaccacttg ggcatagact tgggcgacac gcccgaagaa atcctgacca
     6661 acctgcaagg tcatcattat caaaacaaag acatcaaaca agacgcgggc aaagggcacg
     6721 accacgccta ttgcgaacac gtccgccaag tggacgaacc gaccgccgcg cgtttcaatg
     6781 ccgaccccgc ccgccattac gaagcctcgg gctgcgcggg caaactgatg gtttttgccg
     6841 tccgtttgga caccttcccg caagaaaaac aaaccgccgt gttctacatc ggcacgaacg
     6901 acatcaacga gctgaccgac atccgccgcg ccgccttggg cgaatttgaa agcctgcctg
     6961 tttccggcga atacatccac cgccacgctt tcgacattgc cgacgtgtac ggcaaagaca
     7021 cgttttacgt catcaaaaaa ttcggtacgc accaactgcc gaaattattt gacttgaagg
     7081 cgcgcgtgga caggttcggc aaaaaagcca gcttcctgcc caaacatttt tccgacaagg
     7141 ccatgcagtt cgtcagcaaa tacctgcccg accacctgcc caaatccatg cgcgattacc
     7201 gcgacaaata cgaacaccac ctgattctga aaatgggcgg gaaaggcgtg gatgaggcgc
     7261 gcgcgttctt aaaagaatat tttgcacacc acagcggcgc gtttttcgag tgcaacgccg
     7321 aagaaaccca agccgcgatg ctgcaccgtt tcgccgtcgc ctccgccgcc atccgctacc
     7381 gcgccgtgca tgatgacgaa gtggaagact tggtcgcgct tgacatcgcc ctgcgccgcg
     7441 acgaccgcga ctggtttgaa aaactgccgc ccgaaatcga caataaaatc atccacaaac
     7501 tctactacgg acatttcatg tgccacgttt tccatcagga ttacatcatc aaaaaaggca
     7561 acgactgcat ggcgttggaa cacgaaatgc tgcatctctt agaccaacgc ggcgcgcaat
     7621 atcccgccga acacaacgtc ggtcatttgt atgaagccaa gcccgcgctc aaacagtttt
     7681 accgcaaact cgacccgacc aacagcttca acccgggtat cggcaaaacc agcaaaaaga
     7741 aaaactgggc ggaataagcg cgtccgcttt gaaggcaggc aatgccgtct gaaggcaaaa
     7801 cgccgttcag acggcattgt cgggtttgaa gttccccgtc gggtaatcgc tttcaaaccg
     7861 tatgccgaca cacgggcgcg cccctcccaa atatagtgga ttaaatttaa atcaggacaa
     7921 ggcaacgaag ccgcagacag tacagatagt acggcaaggc gaggtaacgc cgtactggtt
     7981 taaatttaat ccactataaa gtctgatcct accttcccaa agggcagggt ttcaaccgaa
     8041 aaggaaacac gatgaaacca tacaaaatct acacccatcc cgccctgccg ccccaagccg
     8101 tcaaacaagg ctggtcatgg ccggggctct tgttcggcac gctgtgggcg tgtttcaaaa
     8161 gaatgtgggg tttggggctg gggctgacgg gcgcgatatt cgtgctggct gtgtttgccc
     8221 aactggttta cggcgacacg cccgccacag actcggcgtt taacgtattg ggcttggcgg
     8281 tttccgtctg gttcggcgca aagggcaaca gcctttatgc acgccacctt ttatcgcgcg
     8341 gctataccga attgcccgaa acggttgagg cagccaatcc ccaagccgca ttggcgcaat
     8401 atttcgggcg cgggggccga taagcgcgtt ttcttttcca tcatgccgtc tgaaaaatgt
     8461 tcagacggca tttcttataa ccttttgttt gcagcacata accaatcagt ctttcctatt
     8521 ccgttccgaa atgcatacca tgcgcccgta cccaatattt gcgaacaagg aaagaaaatg
     8581 gcacgtttaa ccgtacacac cctcgaaacc gcccccgaag ccgccaaagc gcgcgtcgag
     8641 gcggtacttc aaaacaacgg ctttatcccc aaccttatcg gcgtattatc aaacgccccc
     8701 gaagccttgg cgttttacca agaagtcggc aagctcaacg ccgccaacag cctgaccgcc
     8761 ggcgaagtcg aagtcatcca gatcatcgcc gcccgtacca accaatgcgg tttttgcgtg
     8821 gcagggcaca ccaaactcgc aaccctgaaa aaactcctgt ccgaacaatc cgtcaaagcc
     8881 gcgcgcgctt tggcagcagg cgaatttgac gatgccaaac tcggcgcgct cgccgccttt
     8941 acccaagccg taatggcgaa aaaaggcgcg gtatccgacg aggaactcaa agcatttttc
     9001 gatgcgggct acaaccagca gcaggcagtc gaagtcgtga tgggcgtagc cttggcaacc
     9061 ctgtgcaact acgtcaacaa cctcggacaa accgaaatca accccgaatt gcaggcttac
     9121 gcctgatacg gcaaaccgcc cgaatatcgg gcggtttttc aaaaacaccc cctcaaacaa
     9181 aaacaagccg ccaagcggca gggaagcagc cgcgcatcag gcgcgccccc gattcccccg
     9241 caaaccttaa ggaacaaaga tgaacgccca aaccctgatt gccaacgttg ccgaattcgt
     9301 caaaaccaag ctcaaaccca tagtggacga catcgaccgc aaaggatact accccgaagc
     9361 atttatgcgc gaactcggcg caatcggtgg attcggcgca gtcggtacag aagccgaagg
     9421 cggcaacggc ttgggtttgg caacgcaaat cgccgtattg cgcgaaatcg gcaaagaatg
     9481 cggcgcaacc tctttcagtg cgtggtgtca ggcggcttgc gcgtggtatc tgcaccaaac
     9541 gcccaaccgg gccgtcaaag acaaatacct tgccgacatc ctgcaaggca aagtattggc
     9601 gggtacgggc atgtccaata ccgtcaaaca ccttgccgac atcgaaaaac acaacctcca
     9661 agccgagcgc gtggagggcg gctacacagt caacggcgcg ctgccgtggg tgtccaacat
     9721 cggcgaagac cacatttggg cgaataccgc ccaaatcggc ggcggctacg tcatgttcat
     9781 cacaggcgga caatgggaag gcgtaagcct gcaaaactgc cccgaatttt gcgccctcga
     9841 aggcacgcgc accttcagcc tgaacttcaa agacgtattt atccccgacg aagacatcat
     9901 cgccgcgccc gaacagtttg ccgactacat ccaaagcatc aaagcaggct ttatcctcct
     9961 gcaaatcggc atcggcgcgg gcgtgataga cggcagcctc ggcatcatcc gcctcgccaa
    10021 cgtcgtcaac gccgaagtca accgctatct cgacgacggc tacgacagcc tcaaaacaag
    10081 gctggacggc gcgtgggcag aaaccgaacg gctcgccgga ttggcttgga gcggcacgcc
    10141 cgacaacctt accaccctca agctgcgcga agccgccgcc gtactgacac ttgccgccgc
    10201 ccaatccgcc gccctgcatt ccggcgcaaa aggctacctg atgcggagtc ccgcccaaag
    10261 gcgcgtccgc gaagcaatgt ttgtcgccat cgtaactccc gcgatcaaac acctccgcaa
    10321 agaaatagcg gcaatcgaag ccgcaaaata aacaggcgga aaaaaccgaa acccccaccg
    10381 ccgtcattcc cgcgcaggcg ggaatccagc aacacaacgc ggcaggactt tatcggaaaa
    10441 aacagaaacc ccaccgaccg tcattcccgc gcaggcggga atccagaccc gtcggcacgg
    10501 aaacttaccg gataaaacag tttccttaga ttccacgtcc tagattcccg ccttcgcggg
    10561 aatgacgaga ttttagatta tgggaattta tcaggaatga ttgaatccat agaaaaatca
    10621 caggaatcta tcagaaaaaa cagaaacccc caccgcgtca ttcccgcaaa agcgggaatc
    10681 caaaaacgca acgcaacagg aatctatcgg aaaaaacaga aaccccaccg ccgtcattcc
    10741 cgcaaaagcg ggaatccaga cccgtcggca cggaaactta ccggataaaa cagtttcctt
    10801 agattccacg tcctagattc ccgctttcgc gggaatgacg agattttaga ttatgggaat
    10861 ttatcaggaa tgattgaatc catagaaaaa ccacaggaat ctatcagaaa aaacagaaac
    10921 ccccaccgcg tcattcccgc gcaggcggga atccagaaac gcaacgcaac aggaatttat
    10981 cggaaaaaac agaaaccccc accgcgtcat tcccgcgcag gcgggaatcc agaaacacaa
    11041 cgcggcagga ctttatcgga aaaaacagaa accctcacca ccgtcattcc cgcgcaggcg
    11101 ggaatccaaa aacgcaacgc aacaggaatt tatcagaaaa aacagaaacc ccaccgaccg
    11161 tcattcccgc gcaggcggga atccagaaac acaacgcggc aggactttat cggaaaaaac
    11221 cgaaacccca ccgaccgtca ttcccgcaaa agcgggaatc cagcaaccga aaaaccacag
    11281 gaatctatca gcaaaaacag aaaccccacc gccgtcattc ccgcaaaagc gggaatccag
    11341 acccgtcggc acggaaactt accgaataaa acagtttcct tagattccac gtcccagatt
    11401 cccgccttcg cgggaatgac gagattttaa gttgggggaa tttatcagaa aacccccaac
    11461 cccaaaaaac cgggcggatg ccgcaccatc cgcccccaaa ccccgattta accattcaaa
    11521 caaaccaaaa gaaaaaacaa aatgaacaaa atataccgca tcatttggaa tagtgccctc
    11581 aatgcctggg tcgtcgtatc cgagctcaca cgcaaccaca ccaaacgcgc ctccgcaacc
    11641 gtggcgaccg ccgtattggc gacactgctg tccgcaacgg ttcaggcgaa tgctaccgat
    11701 gaagaagacg atgaagagtt agaacccgta gtacgcactg ctcccgtgtt gagcttccat
    11761 tccgataaag aaggcacggg agaaaaagaa gaagtaggag caagttcaaa tttgacagta
    11821 tatttcgaca agaaaggagt actaaaagcc ggaacaatca ccctcaaagc aggcgacaac
    11881 ctgaaaatca aacaaaacac caatgaaaac aacaatgaaa acaccaatgc cagtagcttc
    11941 acctactcgc tgaaaaaaga cctcacagat ctgaccagtg ttggaactga aaaattatcg
    12001 tttagcgcaa acggcaataa agtcaacatc acaagcgaca ccaaaggctt gaattttgcg
    12061 aaagaaacgg ctgggacgaa cggcgacacc acggttcatc tgaacggtat tggttcgact
    12121 ttgaccgata cgctgctgaa taccggagcg accacaaacg taaccaacga caacgttacc
    12181 gatgacgaga aaaaacgtgc ggcaagcgtt aaagacgtat taaacgcagg ctggaacatt
    12241 aaaggcgtta aacccggtac aacagcttcc gataacgttg atttcgtccg cacttacgac
    12301 acagtcgagt tcttgagcgc agatacgaaa acaacgactg ttaatgtgga aagcaaagac
    12361 aacggcaaga aaaccgaagt taaaatcggt gcgaagactt ctgttattaa agaaaaagac
    12421 ggtaagttgg ttactggtaa agacaaaggc gagaatggtt cttctacaga cgaaggcgaa
    12481 ggcttagtga ctgcaaaaga agtgattgat gcagtaaaca aggctggttg gagaatgaaa
    12541 acaacaaccg ctaatggtca aacaggtcaa gctgacaagt ttgaaaccgt tacatcaggc
    12601 acaaaagtaa cctttgctag tggtaatggt acaactgcga ctgtaagtaa agatgatcaa
    12661 ggcaacatca ctgttaagta tgatgtaaat gtcggcgatg ccctaaacgt caatcagctg
    12721 caaaacagcg gttggaattt ggattccaaa gcggttgcag gttcttcggg caaagtcatc
    12781 agcggcaatg tttcgccgag caagggaaag atggatgaaa ccatcaacat taatgccggc
    12841 aacaacattg agattacccg caacggtaaa aatatcgaca tcgccacttc gatgaccccg
    12901 cagttttcca gcgtttcgct cggtgcgggg gcggatgcgc ccactttaag cgtggatgac
    12961 gagggcgcgt tgaatgtcgg cagcaaggat gccaacaaac ccgtccgcat taccaatgtc
    13021 gccccgggcg ttaaagaggg ggatgttaca aacgtcgcac aacttaaagg tgtggcgcaa
    13081 aacttgaaca accgcatcga caatgtggac ggcaacgcgc gtgcgggcat cgcccaagcg
    13141 attgcaaccg caggtttggc tcaggcgtat ttgcccggca agagtatgat ggcgatcggc
    13201 ggcggtactt atcgcggcga agccggttac gccatcggct actcgagcat ttctgacact
    13261 gggaattggg ttatcaaggg cacggcttcc ggcaattcgc gcggtcattt cggtacttcc
    13321 gcatctgtcg gttatcagtg gtaagggctt tttcgcctgt ctgctgttgg ggcaggcgga
    13381 aggtttgaag ggaagggtgg cgatttgccg cctgagacct ttgcaaaatt ccccaaaatc
    13441 ccctaaattc ccaccaagac atttagggga tttctcatga gcaccttctt tcaacaaacc
    13501 gcgcaagcca tgattgccaa acacatcgac cgtttcccgc tattgaagtt ggatcaggta
    13561 attgattggc agccgatcga gcagtacctg aaccgtcaaa aaaaccgtta cctccgagac
    13621 caccgcggcc gtcctgccta tcccctgctg tccatgttca aagccgtcct gctcggacaa
    13681 tggcacagcc tctccgatcc cgaactcgaa cacagcctca ttacccgcat cgacttcaac
    13741 ctgttttgcc gtttcgacga actgagcatc cccgattaca gcaccttatg ccgctaccgc
    13801 aactggctgg cgcaagacga caccctgtcc gaactgttgg aactgattaa ccgccaactg
    13861 accgaaaaag gcttaaaagt agagaaagca tccgcagccg tcgttgatgc caccattatt
    13921 cagaccgccg gcagcaaaca gcgtcaggcc atagaagtcg atgaagaagg acaaatcaac
    13981 ggtcaaacca caccgagtaa ggacaaagat gcccgttgga taaagaaaaa cggcctctac
    14041 aaactcggtt acaaacaaca tacccgtacc gatgcggaag gctatatcga gaaactgcac
    14101 atcacccccg ccaatgccca tgagtgcaaa cacctgtcgc ctttgctgga aggattgccc
    14161 aaaggtacga ccgtctatgc tgataaaggc tatgacagtg cggaaaaccg gcaacatctg
    14221 aaagaacatc agttactgga cggcattatg cgcaaagcct gccgcaaccg tccgctgacg
    14281 gaggcgcaaa ccaaacgcaa ccgatatttg tcgaaga
//
LOCUS       DAXISH010000055        14131 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.055, whole genome shotgun sequence.
ACCESSION   DAXISH010000055 DAXISH010000000
VERSION     DAXISH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 14131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14131
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.055"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..841)
                     /gene="mafA"
                     /locus_tag="ACFOV4_001630"
     CDS             complement(<1..841)
                     /gene="mafA"
                     /locus_tag="ACFOV4_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin MafA"
                     /protein_id="HFC7619599.1"
                     /translation="MQARLLIPILFSVFILSACGTLTGIPSHGGGKRFAVEQELVAAS
                     ARAAVKDMDLQALHGRKVALYIATMGDQGSGSLTGGRYSIDALIRGEYINSPAVRTDY
                     TYPRYETTAETTSGGLTGLTTSLSTLNAPARSRTQSDGSGSKSSLGLNIGGMGDYRNE
                     TLTTNPRDTAFLSHLVQTVFFLRGIDVVSPANADTDVFINIDVFGTIRNRTEMHLYNA
                     ETLKAQTKLEYFAVDRTNKKLLIKPKTNAFEAAYKENYALWMGPYKVSKGIKPTEGLM
                     VDFS"
     gene            complement(1105..1254)
                     /locus_tag="ACFOV4_001631"
                     /pseudo
     CDS             complement(1105..1254)
                     /locus_tag="ACFOV4_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1480..2199)
                     /gene="pyrH"
                     /locus_tag="ACFOV4_001632"
     CDS             complement(1480..2199)
                     /gene="pyrH"
                     /locus_tag="ACFOV4_001632"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFC7619600.1"
                     /translation="MTQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVK
                     MGVQVGIVVGGGNIFRGVSAQAGSMDRATADYMGMMATVMNALALKDAFETLGIKARV
                     QSALSMQQIAETYARPKAIQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVML
                     KATNVDGVYTADPKKDPSATRYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGI
                     AKEGSLKRVVTGENEGTLVHC"
     gene            complement(2443..3297)
                     /gene="tsf"
                     /locus_tag="ACFOV4_001633"
     CDS             complement(2443..3297)
                     /gene="tsf"
                     /locus_tag="ACFOV4_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003795802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFC7619601.1"
                     /translation="MAEITAKMVADLRAATGLGMMECKKALVEAEGNFDKAEEILRIK
                     SGAKAGKLAGRTAAEGVLAYAINGNVGALVEVNCETDFVAKDAGFVEFANFVAKTAAE
                     KKPATVEELSELVEAERKAIIAKLGENMSVRRFQVIDTANQLVAYIHGALATEGVLVE
                     YKGSEDVARKIGMHIVAAKPQCVSEAEVDAETVEKERHIYTEQAIASGKPADIAAKMV
                     EGRIRKFLAEITLNGQAFVMNPDQTVAQFAKENGTEVVSFVRYKVGDGIEKKAVDYAA
                     EVAAAAKV"
     gene            complement(3426..4154)
                     /gene="rpsB"
                     /locus_tag="ACFOV4_001634"
     CDS             complement(3426..4154)
                     /gene="rpsB"
                     /locus_tag="ACFOV4_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFC7619602.1"
                     /translation="MSQITMRQMIEAGVHFGHQTRFWNPKMAQYIFGARNKIHIVNLE
                     KTLPMFQEAQEAVRRLVANKGTVLFVGTKRQARDIIREEATRAGMPFVDYRWLGGMLT
                     NYKTVKQSIKRLEEKTAALENAAEGGFNKKEILEMQRDVEKLERSLGGIKNMKGLPDA
                     IFVIDTGYQKGTLVEAEKLGIPVIAVVDTNNSPDGVKYVIPGNDDSAKAIRLYCRGIA
                     DAVLEGKNQALQETVAAAQEAAAE"
     gene            complement(4327..4560)
                     /locus_tag="ACFOV4_001635"
     CDS             complement(4327..4560)
                     /locus_tag="ACFOV4_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619603.1"
                     /translation="MWHIVAIGYLFVAVMYSAAQPSIARALIYLVFWAVLPTVFTVFT
                     ITVRRRNHLMRQQEQAESEQQRAQRQKDSGTKP"
     gene            4638..5219
                     /locus_tag="ACFOV4_001636"
     CDS             4638..5219
                     /locus_tag="ACFOV4_001636"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFC7619604.1"
                     /translation="MRNEEKRALRRELRGRRSQMGRDVRAAATVKINHLLKRYIKKGR
                     KIGVYWPMGKELRLDGFVRAAQKRGVKLYLPYIEPRSRRMWFTPYPESGMERERIRGR
                     AKLNVPQFAGRKIRVHGLSVLLVPLVGIDREGYRLGQAGGYYDATLAAMKYRLQAKTV
                     GVGFACQLVGTLPREAHDLPLDGFVSEAGILCF"
     gene            5280..5870
                     /locus_tag="ACFOV4_001637"
     CDS             5280..5870
                     /locus_tag="ACFOV4_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFC7619605.1"
                     /translation="MSEKIILPVLSLGGVRLEPLDVHHETGLREAVCDGEVWKLGVTS
                     APHPDRVADYIGTALATRLAFAVVDEEAGRVVGTTAYYHFEPQIPRLDIGFTWYAASA
                     RRTRINTCCKIMLLDYAFDVLACRCVGWRTDILNLASQRAIERLGAEKDGVLRMHMLR
                     KDGSVRDTVVYSMLREDWCKNREILTGRLAGYGVQV"
     gene            6407..7873
                     /locus_tag="ACFOV4_001638"
     CDS             6407..7873
                     /locus_tag="ACFOV4_001638"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate:quinone oxidoreductase"
                     /protein_id="HFC7619606.1"
                     /translation="MAEATDVVLVGGGIMSATLGVLLKELEPSWEITLIERLEDVALE
                     SSNAWNNAGTGHSALCELNYAPLGANGIIDPARALNIAEQFHVSRQFWATLVAEGKLE
                     DNSFINAVPHMSLVMNEDHCSYLQKRYDAFKTQKLFENMEFSTDRNKISDWAPLMMRG
                     RDENQPVAANYSAEGTDVDFGRLTRQMVKYLQGKGVKTEFNRHVEDIKRESDGAWVLK
                     TADTRNPDGQLTLRTRFLFLGAGGGALTLLQKSGIPEGKGYGGFPVSGLFFRNSNPET
                     AEQHNAKVYGQASVGAPPMSVPHLDTRNVDGKRHLMFGPYAGFRSNFLKQGSLMDLPL
                     SIHMDNLYPMLRAGWANMPLTKYLLGELRKTKEERFASLLEYYPEANPDDWELITAGQ
                     RVQIIKKDSEKGGVLQFGTEIVAHADGSLAALLGASPGASTAVPLMIRLMHQCFPERA
                     PSWEGRLKELVPGYGIKLNENPERADEIIAYTAKVLDI"
     gene            complement(8060..8434)
                     /locus_tag="ACFOV4_001639"
     CDS             complement(8060..8434)
                     /locus_tag="ACFOV4_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFC7619607.1"
                     /translation="MKLLTTAILSSAIALSSMAAAAGTNNPTVAKKTVSYVCQQGKKV
                     KVTYGFNKQGLTTYASAVINGKRVQMPVNLDKSDNVETFYGKEGGYVLGTGVMDGKSY
                     RKQPIMITAPDNQIVFKDCSPR"
     gene            complement(8672..8971)
                     /locus_tag="ACFOV4_001640"
     CDS             complement(8672..8971)
                     /locus_tag="ACFOV4_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC7619608.1"
                     /translation="MKIFENIEDVKAIRKKTGLNQIDFWGKVGVTQSGGSRYETGRKM
                     PKPVRELLRLVHIECIDLAKVNKKDMEIAALLKKHHPDLYAELSKQTKSERKKQS"
     gene            complement(9126..9905)
                     /gene="map"
                     /locus_tag="ACFOV4_001641"
     CDS             complement(9126..9905)
                     /gene="map"
                     /locus_tag="ACFOV4_001641"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFC7619609.1"
                     /translation="MNGIIIKTPEEIEKMRELGKLVAEALDYIGQFVKPGVTTDEIDK
                     LVYDYHVNVQGGYPAPLHYGNPPYPKSCCTSVNHVICHGIPDDKPLKEGDIINIDLTI
                     KKDGFHGDSSRMFTVGKVSPIAQRLIDVTHASMMAGIEAVKPGATLGDVGYACQQVAE
                     NAGYSVVQEFCGHGIGRGFHEAPQVLHYGKKGQGPVLKPGMIFTVEPMINQGKRHLRI
                     LNDGWTVVTKDRSLSAQWEHEVLVTETGYEILTVSPASGKP"
     gene            complement(9945..10673)
                     /locus_tag="ACFOV4_001642"
     CDS             complement(9945..10673)
                     /locus_tag="ACFOV4_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619610.1"
                     /translation="MPSEPPSDGIARHPKSTIKMAKKPNKPFRLTPKLLIRVVLLICI
                     TAIGALAIGIVSTFNPNGGKTLQTEPQHTDSPRETEFWLPNGVVGQDAAQPEHHHAAS
                     SEPAQPDGTDESGSGLPSPAAPKKNRVKPQPADTAQTDRQPDDAGTQAENTLKETPVL
                     PTNVPRPEPRKETPEKQAQPKETPKEKETPKETPKEKETPKETPKEKETPKEKETPKE
                     NHTKPDTPKNTPPKPHKEILDNLF"
     gene            complement(10681..11289)
                     /locus_tag="ACFOV4_001643"
     CDS             complement(10681..11289)
                     /locus_tag="ACFOV4_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003694442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HFC7619611.1"
                     /translation="MKPKPHTVRTLIAAIFSLALSGCVSAVIGSAAVGAKSAVDRRTT
                     GAQTDDNVMALRIETTARSYLRQNNQTKGYTPQISVVGYNRHLLLLGQVATEGEKQFV
                     GQIARSEQAAEGVYNYITVASLPRTAGDIAGDTWNTSKVRATLLGISPATQARVKIVT
                     YGNVTYVMGILTPEEQAQITQKVSTTVGVQKVITLYQNYVQR"
     gene            complement(11353..11946)
                     /locus_tag="ACFOV4_001644"
     CDS             complement(11353..11946)
                     /locus_tag="ACFOV4_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008968 - D-sedoheptulose 7-phosphate
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoheptose isomerase"
                     /protein_id="HFC7619612.1"
                     /translation="MTTLQERVAAHFAESIRAKQEAGKVLVEPTVQAAELMLQCLMND
                     GKILACGNGGSAADAQHFAAEMTGRFEKERMELAAVALTTDTSALTAIGNDYGFDHVF
                     SKQVRALGRAGDVLVGISTSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAILKDT
                     DVLLNVPHPRTARIQENHILLIHAMCDCIDSVLLEGM"
     gene            complement(11951..12298)
                     /locus_tag="ACFOV4_001645"
     CDS             complement(11951..12298)
                     /locus_tag="ACFOV4_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HFC7619613.1"
                     /translation="MRLNHKQGEAGEDAALAFLQSQGCTLLARNWHCAYGEIDLIVKN
                     GGMILFVEVKYRKNRQFGGAAYSISPSKLLKLQRSVEYYLQQNRLTNVPCRLDAVLIE
                     GSRPPEWIQNITG"
     gene            12344..13219
                     /gene="rsmI"
                     /locus_tag="ACFOV4_001646"
     CDS             12344..13219
                     /gene="rsmI"
                     /locus_tag="ACFOV4_001646"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFC7619614.1"
                     /translation="MFQKHLQKASDSVVGGTLYVVATPIGNLADITLRALAVLQKADI
                     ICAEDTRVTAQLLSAYGIQGQLVSVREHNERQMADKIVGYLSDGMVVAQVSDAGTPAV
                     CDPGAKLARRVREVGFKVVPVVGASAVMAALSVAGVAGSDFYFNGFVPPKSGERRKLF
                     AKWVRAAFPIVMFETPHRIGATLADMVELFPERRLMLAREITKTFETFLSGTVGEIQT
                     VLSADGNQSRGEMVLVLYPAQDEKHEGLSESAQNIMKILTAELPTKQAAELAAKITGE
                     GKKALYDLALSWKNK"
     gene            complement(13254..13658)
                     /locus_tag="ACFOV4_001647"
     CDS             complement(13254..13658)
                     /locus_tag="ACFOV4_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HFC7619615.1"
                     /translation="MGSLFGLHKSFGFLTLTVITLRIVWTVANRAKRPQSDSKAAAAG
                     HGILYLLMLAVPVIGMIRQYGSGRGPLKVFGVEVMQGSPEKIEWMANLGNTFHGNLGW
                     LLFAAVVGHVAMVVVHRVQGKDVLYRMTGRVR"
     gene            complement(13723..13887)
                     /locus_tag="ACFOV4_001648"
     CDS             complement(13723..13887)
                     /locus_tag="ACFOV4_001648"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619616.1"
                     /translation="MNTNQPAVYDPLTRTLHWLTVAGFIGIPTTIVLWTIYSGLTKIR
                     TRRRSRRQYK"
     gene            13949..>14131
                     /locus_tag="ACFOV4_001649"
     CDS             13949..>14131
                     /locus_tag="ACFOV4_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006248253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC7619617.1"
                     /translation="MRKSRLSRYKQNKLIELFVAGVTARTAAELVGVNKNTAAYYFHR
                     LRLLIYQNSPHLEMFDG"
BASE COUNT         2976 a         3315 c         4083 g         3757 t
ORIGIN      
        1 cggagaaatc gaccattaat ccttccgtcg gtttaattcc tttgcttact ttatacggcc
       61 ccatccacaa tgcgtaattt tctttatagg cagcttcaaa cgcattggtt ttgggtttga
      121 tgagcaattt tttattggtt ctgtctactg cgaaatattc cagttttgtt tgggctttca
      181 gtgtttcggc attgtatagg tgcatttcgg ttctgttgcg tatcgttccg aatacgtcga
      241 tgttaataaa cacatctgta tcggcattgg caggagaaac aacgtctatg ccgcgcagga
      301 aaaatacggt ctgtaccaag tgggaaagaa aggcagtgtc gcgcgggtta gtcgtcaagg
      361 tttcatttcg ataatccccc atcccgccaa tatttaagcc cagactgctt ttacttccgc
      421 taccgtctga ttgggtgcga gagcgtgcag gggcattaag tgtagataaa gaagtggtta
      481 aacctgtcaa accgcctgat gttgtttcag cggtggtttc gtaacgtgga taggtgtaat
      541 cggtacggac ggcagggctg tttatgtatt cgccacgaat cagtgcatca atggagtagc
      601 gaccccctgt caaactgcct gaaccttggt cgcccatagt tgcaatgtac aatgcaactt
      661 ttcgtccgtg taatgcctgt aaatccatgt ctttaacggc agctctggca gaagcggcca
      721 caagttcttg ttcgaccgca aagcgtttac ctccgccatg cgatggaata cctgtcagtg
      781 tcccgcaggc ggataaaata aaaactgaaa aaagaatagg tatcagcagc cgtgcttgca
      841 tagattttct cctttgatga aaaacaaatt gtatcaaaat tgtaaacaaa ttataaatta
      901 aataaaatat ttctttactg gttttgtggt ttggttttca ataggctgcc cgcacatagt
      961 gggatttacg gttgcaatgg ctgcggcgta ttttatagtg gattaaattt taatcaggac
     1021 aaggcgacga agccgcagac agtacaaata gtacggcaag gcgaggcaac gctgtactgg
     1081 tttaaattta atccactata ggcttttttc ggtcagttgc cggttaatca gtcccggcag
     1141 ttcggacagg gtgttgtctt gcgccaacct gttgcggtag cggcataagg tgctgtaatc
     1201 ggggatgctt ggtttgtcaa aacggcaaaa caggttgaaa tcggtgcggg tgatgggtac
     1261 ggcgttgccc ttatgccgat tttgtccgcc tgctgcaagg cggtttgtct aatgaaagga
     1321 aaaatgccgt ctgaacattg ttcagacggc attttcaaat ggaaggcaat atagtcggca
     1381 tatgaaaaat tgatgtataa ggcaggatgg gtttaggctt gttaatttcc atataataaa
     1441 tggccgtatg aagcccatat gcgactatat ctgccggaat cagcagtgaa ccagtgtacc
     1501 ctcgttttcg ccggttacca cgcgtttgag cgagccttct ttagcgatac cgaatactac
     1561 gatattgagc ttgcgttcgc ggcagagggc gaaagcggtg gcatccatca ctttaaggtt
     1621 tttcaacaag gcttcgtcaa aagtaatggt ttcgtagcgt gttgcagatg ggtctttttt
     1681 cgggtctgcg gtgtacacac cgtcaacgtt ggtggctttg agcatcacgt cgcagttcat
     1741 ttctgcaccg cgcaatgcgg cggcagtgtc ggtcgtgaag aacggattac cggtaccggc
     1801 ggcgaaaatc acgactttgc cttcttccaa atattgaatg gctttaggac gggcgtaagt
     1861 ttcggcgatt tgctgcatag acagtgcgga ttgtacgcgc gctttgatgc ccaaagtttc
     1921 aaatgcgtct ttgagtgcca acgcgttcat tacggttgcc atcatgccca tgtagtcggc
     1981 ggtggcgcgg tccatactgc ctgcttgtgc agatacgcca cggaaaatgt taccgccgcc
     2041 gacaacgata ccgacctgca cgcccatttt aacgacttcg gcaatttcgc cgacagtttg
     2101 aacgatggta tcgtgattga tgccgaacgg atcggaaccc atcagggatt cgccggagag
     2161 tttcagtaat acgcgtttgt atttgatttg ctgtgtcatg ggatattctg ctttctcgtt
     2221 ggggatgttg ccggcttccg ggcgggatgc cgtctgaaag gtgtatgcct tggcagggcg
     2281 tatgcggcgt gccggcggtg tgaaaacggg ctgctgaatt tgccgccgct gttttcgggc
     2341 ggggcgggca tttgaaccct gccgccggaa aatatgggcc tttcccaaaa aaaagcaccc
     2401 tgattcgttt ggaatccagg tgctttcttt ttcataagtg ccttacactt tggcggcagc
     2461 ggctacttct gccgcgtaat cgacggcttt tttctcgata ccgtcgccta ctttgtagcg
     2521 gacgaagctg accacttcag tgccgttttc tttagcgaat tgggcaacag tttggtcggg
     2581 gttcatcacg aacgcttggc cgttcagagt gatttcagcc aagaatttgc ggatacggcc
     2641 ttcaaccatt ttagcggcga tgtcggcagg tttgccggaa gcgatagctt gttcagtgta
     2701 gatgtggcgt tctttttcaa cggtttcagc atctacttcg gcttcactta cgcattgtgg
     2761 tttagcggca acgatgtgca taccgatttt gcgtgctacg tcttcagagc ctttgtactc
     2821 aaccaatacg ccttcggtag ccaaagcacc gtggatgtag gcaaccagtt ggttggcagt
     2881 gtcgatcact tggaagcggc gaacagacat gttctcgccc aatttagcga tgatggcttt
     2941 acgttctgct tcaaccagtt cgctcagttc ttcaacggta gccggttttt tctcggcagc
     3001 ggttttagca acgaagttgg caaattctac gaagcccgcg tctttggcaa cgaagtcggt
     3061 ttcgcagttt acttcgacca atgcgccgac attgccgttg atggcgtaag ctaatacgcc
     3121 ttcggcagcg gtacgaccgg ccagtttacc ggctttcgcg ccggatttga tgcgcaggat
     3181 ttcttcggct ttgtcgaagt tgccttcagc ttcaaccaag gcttttttgc attccatcat
     3241 gcccaagccg gtagcggcgc gcagatcggc aaccattttt gcagtaattt ctgccatttt
     3301 gaatctccta gatttttggg aaatacggaa aggattttcc gcattcggga atcgtgtgcc
     3361 gcgaacggac gttcagacgg catatttgag aaaaggggca taacgcccct cttctgtaca
     3421 ccgaattact cggcagcagc ttcttgggca gcggctacag tttcttgcag cgcttggttt
     3481 ttgccttcca aaactgcgtc ggcgatgccg cggcagtaca ggcggatggc tttggcggag
     3541 tcgtcgttgc cggggataac gtatttcacg ccgtcagggc tgttgttggt atcgactacg
     3601 gcgataacgg ggatgcccaa tttctcagct tcgaccagag tacctttttg gtagccggta
     3661 tcgataacga aaatcgcgtc aggcaggcct ttcatgtttt tgataccgcc caaagaacgt
     3721 tccagttttt caacgtcgcg ttgcatttcc agaatttctt ttttgttgaa accgccttca
     3781 gcagcgtttt ccagggcagc agttttttct tccaggcgtt tgatggattg cttaacggtt
     3841 ttgtagttgg tcagcatacc acccaaccag cggtaatcaa cgaaaggcat accggcacgg
     3901 gtagcttctt cgcggatgat gtcgcgggct tggcgtttgg tacctacgaa caatactgta
     3961 cctttgttgg caaccagacg acgtacggct tcttgcgcct cttggaacat cggcagggtt
     4021 ttttccaagt ttacgatatg gattttgttg cgcgcaccga aaatgtattg tgccattttc
     4081 gggttccaga aacgggtttg gtggccgaag tgaacaccgg cttcaatcat ctgacgcata
     4141 gtaatttgag acattttatt tccttgaaag ggttaagagc acacattcaa tcgcatagaa
     4201 cttgataggt cacgcatatt gtcaagcacc cttcggcgaa agtgggcata agttttaaaa
     4261 aatagtgtgt ttccgaaatg gaaaactgac ggattatagc ggataagatg ccgtctgaaa
     4321 agggattcag ggttttgtgc cgctgtcttt ttgccgttgt gcgcgctgct gttcggattc
     4381 cgcctgttcc tgctgcctca tcaggtggtt gcggcggcgg acggtaatgg tgaaaaccgt
     4441 gaacacggtg ggcagcaccg cccaaaaaac caaataaatc aaggcgcgcg caatactcgg
     4501 ctgcgcggcg gaatacataa cggcaacaaa aagatagccg atggcgacga tgtgccacat
     4561 tgtgtgcgtc ctgtttgaat gttaacaaaa tcgttataat cgcaacattc taccgcaatc
     4621 ctgaaaggcc gtctgaaatg aggaacgagg aaaaacgcgc cctgcgccgc gaattgcgcg
     4681 ggcggcgttc gcaaatgggg cgggacgtgc gggcggcggc aacggtaaaa atcaaccacc
     4741 tgctcaaacg ttatattaaa aaagggcgga aaatcggcgt gtattggccg atgggcaagg
     4801 aattgcgttt ggacggcttt gtccgcgcgg cgcaaaaacg cggtgtaaaa ctttatctgc
     4861 cttatatcga accgcgttcg cggcggatgt ggtttacgcc gtatcctgaa agcggaatgg
     4921 aacgggagcg catacggggc agggcgaagt tgaacgtgcc gcagtttgca gggcgcaaaa
     4981 tccgcgtgca cggtttgtcg gtattgctcg tcccgcttgt cggcatagac cgcgaaggct
     5041 accgcttggg gcaggcaggc ggctattacg atgcgacgct tgcagcgatg aaataccgtt
     5101 tgcaggcaaa aaccgtgggc gtgggctttg cctgccaact ggtcggcacg ctgccgcgcg
     5161 aggcgcacga cctgccgctg gacggttttg tgtcggaggc ggggatattg tgtttttagc
     5221 cgttcagacg gcatttcggg cggaaatgcc gtctgaaggc ggaatattgg gagaaaagga
     5281 tgtcggaaaa gataatactg ccggtcttgt cattgggcgg cgttcggctc gaaccgttgg
     5341 atgtgcatca tgaaacgggt ttgcgcgagg cggtttgcga tggggaggtt tggaagctgg
     5401 gggtaacgtc cgcgccccat ccggataggg tggcagacta tatcgggaca gcattggcaa
     5461 cgcgtttggc gtttgcggtt gtcgatgaag aggcgggcag ggtggtcggg acaacggcgt
     5521 attatcattt tgaaccgcag attccgcgtt tggatatcgg attcacatgg tatgcggcat
     5581 cggcacggcg gacacggata aacacctgtt gcaaaatcat gctgttggat tacgcatttg
     5641 atgttttggc ttgccgttgc gtgggatggc gcacggatat tctgaacctt gcctcgcaac
     5701 gtgccatcga acggctgggt gcggaaaaag acggcgtgct gcgtatgcat atgctccgta
     5761 aagacggcag tgtgcgcgat acggtcgtgt acagtatgct gagggaagat tggtgcaaaa
     5821 acagggaaat cctgaccggc aggttggcag ggtatggcgt gcaggtgtga ggcagtattt
     5881 tcaaatttat agtggattaa caaaaaccag tacggcgttg cctcgcctta gctcaaagag
     5941 aacgattctc taaggtgctg aagcaccaag tgaatcggtt ccgtactatt tgtactgtct
     6001 gcggcttcgt cgccttgtcc tgatttttgt taatccacta taaaaaactt aacgcaatat
     6061 gctgacaatc ttttaaaaat taatatataa acaattttga ttttttatct attaaaaatt
     6121 tgatatatat agataaataa ctatttttat ttttcatttc gcagtttccc gacttggcgg
     6181 gcgacagaaa aactttgcat ttcccagtaa aatccactac attcacgata acatattaca
     6241 agcccctgaa gcggtgtcgg aagccatgct tgcaacgcat tccaaccccg aaacagcata
     6301 ctcggacaca caccattgcc ggttttccct gcttttgcga ttcaggcgtt tgtagtacgg
     6361 caaataacca taagggcaga agatgcctgt tttttaggag taaaccatgg ctgaagcgac
     6421 agacgttgtc ttggtgggcg gcggcattat gagcgcgact ttgggcgttt tgctcaaaga
     6481 actcgaaccg tcttgggaaa tcaccctgat tgaacgcttg gaagatgtgg cgttggaatc
     6541 gtcaaacgcg tggaacaacg ccggcacggg gcattccgcg ctgtgcgaat tgaactatgc
     6601 gccgttgggt gcaaatggga ttatcgatcc ggcgcgcgcc ctcaatattg ccgaacagtt
     6661 tcatgtcagc cgccagtttt gggcgacgct ggtcgcggaa ggcaagttgg aagacaattc
     6721 cttcatcaat gccgtgccgc atatgtcttt ggtgatgaat gaagaccatt gttcttatct
     6781 tcaaaaacgt tatgacgcgt ttaaaaccca aaaacttttt gaaaatatgg aattttccac
     6841 cgatcggaac aaaatttccg attgggctcc gctgatgatg cgcggccggg acgaaaacca
     6901 acccgtcgcc gccaactact ccgccgaagg cacggatgtc gatttcggac ggctgacgcg
     6961 ccaaatggtg aaatatttgc agggcaaggg cgtaaaaacc gagttcaacc gccacgtcga
     7021 agacatcaaa cgcgaatccg acggcgcgtg ggtgctcaaa accgccgata cccgcaaccc
     7081 cgacgggcag ctcaccctcc gtacccgctt cctcttcctc ggcgcgggcg gcggcgcgct
     7141 gaccctgctg caaaaatccg gcatccccga aggcaaaggc tacggcggct tccccgtgtc
     7201 cggcctgttc ttccgcaaca gcaaccccga aaccgccgaa caacacaacg ccaaagtgta
     7261 cgggcaggct tccgtcggcg cgccgccgat gtccgtcccg cacctcgaca cacgcaacgt
     7321 ggacggcaaa cgccacctta tgttcggccc ttacgcaggc ttccgttcca acttcctcaa
     7381 gcaaggctcg cttatggatt tgccgctgtc catccatatg gacaatctct atcctatgct
     7441 gcgcgccggc tgggcgaata tgccgctgac caaatacctg ctgggcgaat tgcgtaaaac
     7501 caaagaagaa cgcttcgcct ccctgctgga atactacccc gaggcaaacc ccgacgactg
     7561 ggaactcatc accgcagggc aacgcgtcca aatcattaaa aaagactccg aaaaaggcgg
     7621 cgtgctccag tttggtacgg agattgtcgc ccacgccgac ggctcactcg ccgcattgct
     7681 gggcgcgtcg ccgggcgcat cgaccgctgt gccgctgatg atccggctga tgcaccaatg
     7741 cttccccgag cgcgccccgt cttgggaagg tcgtctgaaa gagctggtac cgggttacgg
     7801 catcaagttg aacgaaaacc ctgaaagggc ggatgaaatt atcgcctata ccgcgaaagt
     7861 gttggatatt taagccgaat ctttcaagaa aagccgtacc cccatatggt gttgatgccg
     7921 tccctgccgg ttatgccctt catccggcag ggcaggtttt ggtacacggg gcaggtaatc
     7981 gttttttccc ttttgtgaat aatggaacag tcaaaaaaca gcgttttcat ttctgaaaac
     8041 gctgtttttt gttgcctgat taacgtgggg aacagtcttt gaagacgatt tggttgtcag
     8101 gtgcggtaat cataatgggc tgtttgcggt aggatttacc atccatcacg ccggtaccca
     8161 aaacataacc gccttctttg ccgtagaatg tttccacatt gtcggatttg tccaaattga
     8221 caggcatttg cacgcgtttg ccgttgatga cggcggaagc gtatgtggtc aggccctgtt
     8281 tgttgaagcc gtaggttact ttgacttttt taccttgctg gcagacgtag ctgacggttt
     8341 ttttggcaac ggtggggttg ttcgtgccgg cagcagcagc catactgctg agcgcgattg
     8401 cggaagacag gattgcggtg gtcagaagtt tcatttttat tcctttggat ggatgtggag
     8461 tttgcccgtt tcgagctgtt tgacattcta atgtcggcgt atcctgaaat aaacaggaaa
     8521 ttggataaag tttgtaaaaa ggcgggttcg ggcggttcgg cggtttgagg caggggcggc
     8581 aggcgggata cggcggcctg tccggtgttt cagacggcat tgtttgcgtt tttcggaaat
     8641 gaaaaacctt cgggcatccg gaggttgcgg tttaactttg tttttttctt tcggacttgg
     8701 tctgtttgga caattcggca tacaggtcgg gatggtgttt tttcaacagg gcggcgattt
     8761 ccatatcttt tttgttgact ttcgccaaat cgatgcattc gatatggacg aggcggagca
     8821 gttcgcgtac gggtttgggc attttgcggc cggtttcgta gcgcgagcct ccagactggg
     8881 taacgccgac cttgccccag aagtctatct ggttcagccc ggtcttttta cggatggctt
     8941 taacatcttc tatattttca aatattttca taaaacttcc tttaagtttg tctggttgcg
     9001 gggcaaattc cgatttgctt tgttttcgta atgtgccggg tcaagcctgt ttttatatta
     9061 tatatcatat ctgccgtttc tttcagacgg cattgtttgt ttttatgggg cggatacgtc
     9121 cggtttcagg gtttgccgga ggcggggctg acggtgagga tttcgtagcc ggtttcggtc
     9181 accaagactt cgtgttccca ttgggcggag agggagcggt ctttggtaac caccgtccag
     9241 ccgtcgttga ggatacgcag gtggcgtttg ccttggttga tcatcggttc gacggtaaaa
     9301 atcatacccg gttttagaac ggggccctgt cctttttttc cgtagtgcaa cacttgcggg
     9361 gcttcgtgga aaccgcgccc gatgccgtgt ccgcagaatt cctgtacgac ggaatagccg
     9421 gcgttttcgg caacctgttg gcaggcgtaa cctacgtcgc ccagtgtcgc gccgggtttg
     9481 acggcttcta tgcccgccat catggaggcg tgggttacgt cgatcaggcg ttgggcgatg
     9541 ggggagactt tgccgacggt aaacatacgg ctggagtcgc cgtggaagcc gtcttttttg
     9601 atggtgaggt cgatgttgat aatgtcgcct tctttgagcg gcttgtcgtc gggaatgccg
     9661 tggcagatga cgtggttgac ggaggtgcag caggatttgg ggtagggcgg gttgccgtag
     9721 tgcagggggg cgggatagcc gccttggacg ttgacgtggt agtcgtaaac gagtttgtcg
     9781 atttcgtcgg tggttacgcc gggtttgacg aattgtccga tgtagtcgag ggcttcggcg
     9841 acgagtttgc ccagctcgcg cattttttcg atttcttcgg gggttttgat gatgatgccg
     9901 ttcataatgc ttccttggat tgcgggtgtg cctgccgtgc cgggtcagaa gaggttgtcg
     9961 agaatttctt tatggggttt gggcggcgtg tttttcgggg tgtccggttt ggtatggttt
    10021 tctttgggcg tttctttttc tttgggcgtt tctttttctt tgggtgtttc tttgggcgtt
    10081 tctttttctt tgggtgtttc tttgggcgtt tctttttctt tgggtgtttc tttgggctgc
    10141 gcctgttttt cgggtgtttc ttttcggggt tcgggacggg ggacgtttgt gggcagtacg
    10201 ggggtttctt tgagtgtgtt ttcagcttgt gttccggcgt cgtccggctg cctgtcggtt
    10261 tgagctgtgt cggcaggttg cggtttgacc cggtttttct tgggtgcggc aggggacggc
    10321 agtccgctgc cgctttcgtc tgtgccgtcc ggctgtgcgg gttcggatga ggcggcgtgg
    10381 tggtgttcgg gttgggcggc atcttgtccg actacgccgt ttggcagcca gaattcggtt
    10441 tcgcgggggc tgtcggtgtg ttgcggttcg gtttggaggg ttttgccgcc gttcgggttg
    10501 aatgtgctga cgatgcctat tgccaatgcg ccgatggcgg tgatacagat gagcaatacg
    10561 acacgtatca ggagtttggg ggtcagcctg aagggtttgt tcggtttttt tgccattttg
    10621 attgtgcttt tggggtgtcg ggcaatgccg tctgaaggcg gttcagacgg cattgccgag
    10681 tcagcgttgg acgtagtttt ggtagagggt gatgactttt tgtacgccga cggtggtgct
    10741 gactttttgg gtaatctgcg cctgttcttc gggggtgagg atgcccataa cgtaggttac
    10801 gttgccgtag gtaacgattt tgacgcgcgc ctgtgtggcg gggctgatgc ccaacagcgt
    10861 ggcgcggact ttggatgtgt tccaagtgtc gccggcgatg tcgccggcag tgcgcggcag
    10921 ggaggcgacg gtaatgtagt tgtatacgcc ttcggcggcc tgttcggaac gtgcaatctg
    10981 accgacgaac tgtttctcgc cttcggtggc gacttgtccg agcagcagca ggtggcggtt
    11041 gtagccgaca acggagattt ggggcgtgta gcctttggtt tggttgtttt ggcgcagata
    11101 ggagcgggcg gtggtttcga tacgcaacgc cataacgttg tcgtcggttt gcgcgccggt
    11161 ggttcggcgg tcgacggcgg atttcgcgcc gacggcggcg cttccgatta ctgcgctgac
    11221 gcagccgcta agggcaaggc tgaaaatggc ggcaatcagg gtgcggacgg tgtgcggttt
    11281 gggtttcatc gggtgcttcc tttcttgggc gtttcagacg gcattgcttt gcgccatgcc
    11341 gtctgaaaag ggttacattc cttccagcag tacggagtcg atacagtcgc acatggcgtg
    11401 tatcagcagg atgtggtttt cttgaatacg ggcggtgcgc ggatggggaa cgttgagcaa
    11461 aacgtcggtg tctttgagta tggcggcgat tttgccgccg tcgcggccgg tcaaggcgat
    11521 gacgtgcata tcgcgttcgt gtgcggcttt gacggcttcg atgacgttgg cggaattgcc
    11581 ggaggtggaa atgccgacca atacatcgcc tgcacgtccg agcgcgcgca cctgtttgct
    11641 gaatacgtgg tcgaaaccgt agtcgttgcc gatggctgtc agcgcggaag tgtctgttgt
    11701 cagcgcgaca gcggcgagtt ccatgcgttc tttttcaaaa cggccggtca tttcggcggc
    11761 gaagtgttgc gcgtcggcag ccgaaccgcc gttgccgcag gccaggattt tgccgtcatt
    11821 catcaggcat tgcagcatca gctcggcagc ctgtacggtc ggctcgacca atacttttcc
    11881 ggcttcctgc ttggcacgga tgctttcggc aaaatgggcg gcaacgcgtt cttgtaatgt
    11941 cgtcatatcg tcaacctgta atattctgta tccactcggg cgggcggctg ccttcgatga
    12001 gtaccgcgtc gaggcggcac ggtacgtttg tcaacctgtt ctgttgcaga taatactcta
    12061 cacttcgttg cagtttcaat aatttggatg gggaaatgct gtatgcggca ccgccgaatt
    12121 gccgattttt gcggtatttt acttcaacaa acagaatcat gccgccgttt ttgacaatca
    12181 ggtcgatttc gccgtaggcg cagtgccagt tgcgggcaag cagtgtgcag ccttgggatt
    12241 ggaggaaggc aagcgcggca tcttcccctg cctcgccctg tttgtggttt aggcgcataa
    12301 tcggtttaac ctttataatg tttgtttttc agacggcatt cttatgtttc agaaacattt
    12361 gcagaaagcc tccgacagcg tcgtcggagg gacattatac gtggttgcca cgcccatcgg
    12421 caatttggcg gacattaccc tgcgcgcttt ggcggtattg caaaaggcgg acatcatctg
    12481 tgccgaagat acgcgcgtta ccgcgcagct tttgagcgcg tacggcattc agggccaact
    12541 cgtcagcgtg cgcgaacaca acgaacggca gatggcggac aagattgtcg gctatctttc
    12601 agacggcatg gttgtggcac aggtttccga tgcgggtacg ccggccgtgt gcgacccggg
    12661 cgcgaaactc gcccgccgcg tgcgtgaggt cgggtttaaa gttgtccctg ttgtcggcgc
    12721 aagcgcggtg atggcggctt tgagtgtggc tggtgtggcg ggatccgatt tttatttcaa
    12781 cggttttgta ccgccgaaat cgggcgaacg taggaaattg tttgccaaat gggtgcgggc
    12841 ggcatttcct atcgtcatgt ttgaaacgcc acaccgaatc ggggcaacgc ttgccgatat
    12901 ggtggaattg ttccccgaac gccgattaat gctggcgcgc gaaattacga aaacgtttga
    12961 aacgttctta agcggcacgg ttggggaaat tcagacggta ttgtctgccg acggcaacca
    13021 atcgcgcggc gagatggtgt tggtgcttta tccggcgcag gatgaaaaac acgaaggctt
    13081 gtccgagtcc gcgcaaaaca tcatgaaaat cctcacagcc gagctgccga ccaaacaggc
    13141 ggcggagctt gccgccaaaa tcacgggcga gggaaaaaaa gctttgtacg atctggcact
    13201 gtcttggaaa aacaaatgat gccggacgga ccggcaccat agtgcgaacg gaatcaacgg
    13261 acacgccccg tcatgcggta cagcacgtct ttgccttgaa cacggtggac gacgaccatg
    13321 gcgacgtgtc cgacgacggc ggcaaacagc agccagccca aattgccgtg gaacgtgttg
    13381 cccaagtttg ccatccactc gattttttcc ggcgaaccct gcatcacttc aacgccgaac
    13441 actttcaacg ggccgcggcc gctgccgtat tggcggatca tgccgataac gggaacggca
    13501 agcatgagca gatacagaat gccgtgtcct gccgccgcag ccttgctgtc gctttgcgga
    13561 cgcttggcgc ggttggcaac cgtccacacg atgcgcaatg taatcaccgt cagcgtaagg
    13621 aaaccgaaag atttgtgcag gccgaacagg ctgcccaccc attccgcctc ttcgtatagt
    13681 ggattaacaa aaaccagtac ggcgttgcct cgccttgccg tactatttgt actgtctgcg
    13741 gcttcgtcgc cttgtcctga tttttgttaa tccactataa atcgtccaca ggacaatggt
    13801 ggtcggaatg ccgatgaaac cggcaacggt cagccagtgc agcgtacgtg tcaacgggtc
    13861 gtaaacggca ggttggtttg tgttcataaa aaacttaggg gctgtcctag ataactaggg
    13921 aaattcaaat taagttagaa ttatccctat gagaaaaagt cgtctaagcc ggtataaaca
    13981 aaataaactc attgaactgt ttgtcgcagg tgtaactgca agaacggcag cagagttagt
    14041 aggcgttaat aaaaataccg cagcctatta ttttcatcgt ttacgattac ttatttatca
    14101 aaacagtccg catttggaaa tgtttgacgg c
//
LOCUS       DAXISH010000056        13193 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.056, whole genome shotgun sequence.
ACCESSION   DAXISH010000056 DAXISH010000000
VERSION     DAXISH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 13193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13193
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.056"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            65..928
                     /gene="galU"
                     /locus_tag="ACFOV4_001650"
     CDS             65..928
                     /gene="galU"
                     /locus_tag="ACFOV4_001650"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFC7619618.1"
                     /translation="MQKIRKAVFPVAGMGTRFLPATKASAKEMLPIVDKPLIQYAAEE
                     AVAAGCTELIFITGRNKRNIEDHFDKAYELETELEMREKHKLLGYVQKILPDHVSCIF
                     IRQAEALGLGHAVLCARPAVGNEPFAVILADDLIDAPQGALKQMVDIYNQSGNSILGV
                     ETVDPSQTGSYGIVEVEQLKSYQRVTNIVEKPKPEDAPSNLAVVGRYILTPRIFDLLT
                     NLPRGAGGEIQLTDGIARLLDHEFVLAHAFEGKRYDCGSKLGYLEATVAYGLKHPELK
                     DDFKELLKQFV"
     gene            1011..2027
                     /gene="galE"
                     /locus_tag="ACFOV4_001651"
     CDS             1011..2027
                     /gene="galE"
                     /locus_tag="ACFOV4_001651"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFC7619619.1"
                     /translation="MNILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRL
                     KTITGQEIPFYQGDIRDREILRRIFAENRIDSVIHFAGLKAVGESVAEPIKYYDNNVS
                     GSLVLAEEMARAGVFSIVFSSSATVYGDPGKVPYTEDMPPGDTTSPYGASKSMVERIL
                     TDIQKADPRWSMILLRYFNPIGAHESGLIGEQPNGIPNNLLPYICQVAAGKLPQLAVF
                     GDDYPTPDGTGMRDYIHVMDLAEGHVAAMQAKSNVAGTHLLNLGSGRASSVLEIIRAF
                     EAASGLTIPFEIKPRRAGDLACFYADPSYTKAQIGWQTQRDLTQMMEDSWRWVSNHPN
                     GYDD"
     gene            2123..3184
                     /gene="rffG"
                     /locus_tag="ACFOV4_001652"
     CDS             2123..3184
                     /gene="rffG"
                     /locus_tag="ACFOV4_001652"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFC7619620.1"
                     /translation="MKKILVTGGAGFIGSAVVRHIINDTQDAVVNVDKLTYAGNLESL
                     ESLANHPRYAFEQVDICDRAALDRVFAEHQPDAVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWHDMPSEKKAAFRFHHISTDEVYGDLHGTDDLFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTIVTNCSNNYGPYHFPEKLIPLMILNALDGKPLPVYG
                     DGMQIRDWLFVEDHARALYQVVTEGEIGETYNIGGHNEKANIEVVRTICALLEELVPN
                     KPQGVARYEDLITYVKDRPGHDVRYAIDAAKIGRELGWQPQETFESGIRKTVEWYLNN
                     QTWWSRVLDGSYNRERLGS"
     gene            3397..4272
                     /gene="rfbA"
                     /locus_tag="ACFOV4_001653"
     CDS             3397..4272
                     /gene="rfbA"
                     /locus_tag="ACFOV4_001653"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFC7619621.1"
                     /translation="MKGIILAGGSGIRLYPITRGVSKQLLPVYNKPMIYYPLSVLMLA
                     GIRDVLVITTPEDNDAFRRLLGDGSDFGIQISYAIQPSPDGLAQAFLIGEEFIGDDSV
                     CLVLGDNIFYGQHFSQSLKEAAASVETKGATVFGYQVKDPERFGVIEFDENFKALSIE
                     EKPKQPKSDWAVTGLYFYDNRVVEFAKQVKPSERGELEITTLNQMYLDDGSLNVQLLG
                     RGFAWLDTGTHASLLEAASFVETIENIQNLQVACLEEIAWRNGWLSSEEIRNLAKPMC
                     KNEYGRYLLRLVGKD"
     gene            4327..4866
                     /gene="rfbC"
                     /locus_tag="ACFOV4_001654"
     CDS             4327..4866
                     /gene="rfbC"
                     /locus_tag="ACFOV4_001654"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFC7619622.1"
                     /translation="MNIIDTRIPDVKLLEPKVFGDERGFFMETFRDEWFRQNVAERTF
                     VQENHSKSTQGVLRGLHYQTENTQGKLVRVVSGEVFDVAVDMRRDSPTFGHWVGEVLS
                     ADNKRQLWVPEGFAHGFYVLSDEAEFVYKCTDYYNPNAEHSLIWNDATVGIDWPLLGE
                     PSLSAKDLAGKMLAEAATF"
     gene            5028..7076
                     /locus_tag="ACFOV4_001655"
     CDS             5028..7076
                     /locus_tag="ACFOV4_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HFC7619623.1"
                     /translation="MIPAYIPLRSFGIRKIPNITQFLPEYSLNKTVFNAQTIIGWGLR
                     PTTHQARAFAQSHGLPFVALEDGFLRSLGLGVAGYPPFALVYDDIGIYYDTTRPSRLE
                     QLILAANMPSEMLNQAQQAIDLILTHRLSKYNHALDFSDGLVQDSKNIVLVIDQTFGD
                     MAIQYGGADEATFRQMFQTALAENPDAEIWVKTHPDVLSGKKQGYLTDLAQQPRVRLL
                     AEDINPISLLQAVDKVYCVTSQMGFEALLCGKPLVTFGLPWYAGWGVSDDRHPEINRL
                     VQTQRRATRNLLQLFAAAYLQYSRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELY
                     CVGMSLWKRAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARILAWGNGKEAIVRFAE
                     QHHIPLLRMEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQ
                     DFQTALKLQKMLTENHISKYNVGSSDFTAPSTDKTVILVPGQVEDDASIRYGSPQIYR
                     NLDLLRTVRERNPNAYIIYKPHPDVVSGNRIGHISPEDAARYADQTAEQADILTCLQY
                     ADEIHTMTSLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELWQLIAGT
                     LIHYPDYIHPETHQAINAETAAQILIRQKNMQKNNNGLHRGCFAKKLGKIKQLYRSFK
                     "
     gene            7213..8472
                     /locus_tag="ACFOV4_001656"
     CDS             7213..8472
                     /locus_tag="ACFOV4_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis protein"
                     /protein_id="HFC7619624.1"
                     /translation="MKQTVLKNNLQNLLESAENILLLQGPVGDFFLRLADWLTANGKT
                     VHKFNFNAGDDYFYPPTQAHTVVFNDDYDAFPEFLQEYIVQYHIRAVVCFGDTRPYHV
                     IAKRIANENQVGFWAFEEGYFRPYYITLEKDGVNAFSPLPRRADFFLEQFPKLAQQEY
                     KAPTPVRVGFTPMAKNAIRYYIELFRNLRKYPDYIHHRAPNAGHYLKPWSLSILKRLN
                     YYIEDIQIAKRVEAGKYGKFFIVPLQVFNDSQVRIHCDFPSVRSFLLHVLSSFAEHAP
                     ADTNIIIKHHPMDRGFIDYWRDIKRFIKEHPELQGRVIYVHDVPLPVFLRHGLGMVTI
                     NSTSGLSGLIHNMPVKVLGRAYYDIPGITDQNTLAEFWNHPTPPDKELFHAYRMYHLN
                     VTQINGNFYSQVFFPNKNTSDSSTPTT"
     gene            8842..10248
                     /locus_tag="ACFOV4_001657"
     CDS             8842..10248
                     /locus_tag="ACFOV4_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619625.1"
                     /translation="MTAAPDILYRQAAALLEQSNTAQALPLLQQAAEQGYTEAAFVLG
                     DHLLQNGHPEQALPWLEAAAAQRHPKALFILLQQRAHNGTPTGQLLNEYAWLSEQGHL
                     EAQLILMRYHTQRNDPQSLYWAELAAARYAAPAYYHLARHHQRQGDVATAIEQYEKAA
                     ALGVTAACWQLGQIYFYGTGVSPNHTQAEHYLEQAAQAGHIAAQTLLADLLAAQRKPE
                     ALEWYRRAADKEQAEAQAKLAQYALTGELSERDPFQAARYAKAAAEKNHPEALKIMGD
                     LYRYGLGIKADNHIAQDYYHRAAALGSAAAAQKLISDAALYHPQQYEQIKTAALQQQQ
                     TETIYRLAEAQACAIGRPADYNAARKNYMEAAGFHHKNAAAALGRIYHYGLGTAQDPR
                     AAAHWYAIAAEQNHPSAQYHLACFYYHGQGVGCHVPTACYWLQAAISNGHTSAESLIS
                     LLEQWRREAHHAIGQKAV"
     gene            10466..11680
                     /gene="gltS"
                     /locus_tag="ACFOV4_001658"
     CDS             10466..11680
                     /gene="gltS"
                     /locus_tag="ACFOV4_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HFC7619626.1"
                     /translation="MEWEFNSYYTLIAATLVLLVGKFLVQKIKFLRDFNIPEPVAGGL
                     VAAIILFALHEAYGVSFKFEKPLQNAFMLIFFTSIGLSADFSRLKAGGLPLVVFTAIV
                     GGFILVQNFVGVGLATALGLDPLIGLITGSVSLTGGHGTSGAWGPNFETQYGLVGATG
                     LGIASATFGLVFGGLIGGPVARRLINKMGRKPVENKKQDQDDNADDVFEQAKRTRLIT
                     AESAVETLAMFAACLAFAEIMDGFDKEYLFDLPKFVWCLFGGVVIRNILTAAFKVNMF
                     DRAIDVFGNASLSLFLAMALLNLKLWELTGLAGPVTVILAVQTVVMVLYATFVTYVFM
                     GRDYDAAVLAAGHCGFGLGATPTAVANMQSVTHTFGASHKAFLIVPMVGAFFVDLINA
                     AILTGFVNFFKG"
     gene            11779..12795
                     /locus_tag="ACFOV4_001659"
     CDS             11779..12795
                     /locus_tag="ACFOV4_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HFC7619627.1"
                     /translation="MYRKLIALPFALLLAACGREEPPKALECANPAVLQGIRGNIQET
                     LTQEARSFAREDGRQFVDADKIIAAAYGLAFSLEHASETQEGGRTFCIADLNITVPSE
                     TLADAKANSPLLYGETALSDIVRQKTGGNVEFKDGVLTAAVRFLPVKDGQTAFVDNTV
                     GMAAQTLSVALLPYGVKSIVMIDGKAVKKEDAVRILSGKAREEEPSKPTPEDILEHNA
                     AGGDAGVPQAAEGAPEPEILHPDDGERADTVTVSRGEVEEARVQNQRAESEITKLWGG
                     LDTDVQKELVGEQRKWAQEKISNCRQAAAQADRQEYAEYLKLQCDTRMTRERIQYLRG
                     YSID"
     gene            12806..13003
                     /locus_tag="ACFOV4_001660"
     CDS             12806..13003
                     /locus_tag="ACFOV4_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619628.1"
                     /translation="MTTVPKSRIPVKPLPEKTTDEAKVEKWRQLGAEHGLSGEWAVAA
                     RLGENGFTEEQMENIANLFGR"
     gene            13021..13170
                     /locus_tag="ACFOV4_001661"
     CDS             13021..13170
                     /locus_tag="ACFOV4_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619629.1"
                     /translation="MPSETLLSVSDGILTNTVRRRKTAGFSCVAYADVSTRRTIYKAL
                     PYVPS"
BASE COUNT         3385 a         3447 c         3155 g         3206 t
ORIGIN      
        1 ttaaatttac taaataattt ttactatggg ttgccttatt tatttcaaag gagtgacata
       61 aaaaatgcaa aaaattcgta aagctgtatt ccctgtagct ggcatgggaa cccgattctt
      121 acctgccacg aaagccagcg ctaaagaaat gctgccaatc gtggacaaac cgttaattca
      181 atatgctgcg gaagaagccg ttgccgcggg ttgtactgaa ttgattttta tcaccggccg
      241 taataagcgt aatattgaag accacttcga taaagcctat gagttggaaa ctgaactgga
      301 aatgcgtgaa aagcataaat tgcttggcta tgtgcaaaaa attctgcctg atcatgtcag
      361 ctgtattttc attcgtcagg cagaagcttt gggcttgggt catgcggtat tatgcgcccg
      421 tcctgctgtc ggtaatgagc cttttgccgt gattttggcc gatgacttga ttgatgcacc
      481 acaaggcgca ctcaagcaga tggtagatat ttacaatcaa agcggcaaca gcattttagg
      541 ggtagaaaca gtcgatcctt cgcaaaccgg ttcatacggc attgtcgaag tggaacagct
      601 gaaaagctat cagcgtgtaa ccaatattgt ggaaaaacca aagcctgaag atgcgccgtc
      661 aaatttagcg gtagtcggcc gttatatttt gacaccgcgt atttttgatt tgctgactaa
      721 tctacctcgt ggtgcaggtg gtgaaatcca gctaactgat ggtattgccc gcctacttga
      781 ccatgaattt gtcttggcgc atgcgtttga aggtaagcgt tatgattgtg gcagtaagtt
      841 gggctatctg gaagccacgg tagcttatgg cttgaagcat cccgaattaa aagatgattt
      901 caaagaatta ttgaagcaat ttgtataatt ttaaggccgt ctgaaaaaga aaaggcatca
      961 tgttttttac actttcaggc ggccttttaa acataaagaa ggaaaacgtg atgaacattc
     1021 tcgttaccgg cggcaccggt tttatcggct cgcacaccgt tgtttctttg ctgaaaagcg
     1081 gtcatcaagt cgtgattttg gataacctat gcaattccag catcaatatc ctgccacgct
     1141 tgaaaacgat taccggccaa gagattccgt tttatcaagg cgatatccgc gatcgtgaga
     1201 ttttgcgccg tatttttgcg gaaaaccgca ttgattcggt gattcatttt gccggcttga
     1261 aagcggtggg tgaaagtgtg gccgagccga taaaatatta tgataataat gtttccggca
     1321 gcttggtgtt ggcggaagaa atggcgcgtg cgggcgtgtt tagcattgtg ttcagttctt
     1381 cggcgacggt ttatggcgat ccgggcaaag tgccttatac cgaggatatg ccaccgggcg
     1441 acaccaccag cccttacggc gcatcgaaat cgatggttga gcgcattctc actgacattc
     1501 aaaaagccga tccgcgctgg agcatgattt tgttgcgtta tttcaatccg attggcgcgc
     1561 atgaaagcgg tttgattggc gagcagccaa acggtatccc aaataatttg ttgccttata
     1621 tctgccaagt ggcggcaggc aaactgccgc aattagcggt attcggtgat gactacccta
     1681 cccctgatgg cacgggtatg cgcgactata ttcatgtgat ggatttggca gaaggccatg
     1741 tcgcggctat gcaggcgaaa agcaatgtag caggcacgca tttgttgaac ttaggttccg
     1801 gccgcgcttc ttcggtattg gaaatcatcc gcgcatttga agcggcttcg ggtttaacca
     1861 ttccatttga aatcaaaccg cgccgcgccg gtgatttggc gtgcttctat gccgaccctt
     1921 cttatacgaa ggcgcaaatc ggctggcaaa cgcagcgtga tttaacccaa atgatggaag
     1981 attcatggcg ctgggtaagt aatcatccga atggttatga tgattaagtc atgaaattga
     2041 gaggccgtct gaagtttcag acggcctttg tttgcgattt atagtaaaat ttaccttatc
     2101 attttggcga ttaatattca tcatgaaaaa aatccttgtc accggcggtg ccggttttat
     2161 cggttcggcg gttgtacgcc atatcatcaa cgatacgcaa gatgcggtgg tgaatgtgga
     2221 taagctcacg tatgcgggca atttggaatc gctggaatct ttggccaatc atccgcgcta
     2281 tgcgtttgag caagtcgata tttgcgaccg cgcggcactg gatcgtgtgt ttgccgaaca
     2341 ccagccggat gcggtgatgc acttggcagc agaaagccat gttgaccgca gtattgatgg
     2401 cccagcggca tttattgaaa ccaatattgt tggtacttac acgcttttgg aagcggcgcg
     2461 cgcgtattgg catgatatgc cgtctgaaaa aaaagcggct ttccgtttcc atcatatttc
     2521 gactgatgaa gtgtatggcg atttgcacgg cacggatgat ttgtttaccg aaaccacgcc
     2581 ttacgcccct tccagtcctt attcggcttc caaagcctcc agcgaccatt tggtgcgcgc
     2641 atggctgcgt acttacggcc tgccgaccat tgtgaccaat tgttctaata actacggccc
     2701 ttatcatttt cctgaaaaac tgattccact gatgattctg aatgcgcttg atggcaaacc
     2761 gctgccggtg tatggcgacg gtatgcagat tcgtgattgg ctgtttgttg aagatcatgc
     2821 gcgtgcgctg tatcaagtgg tcacagaagg cgaaatcggc gaaacttaca acattggtgg
     2881 ccacaatgaa aaagccaata ttgaagtggt gcgcaccatt tgcgccctgc tggaagaatt
     2941 ggtgccgaac aaaccgcaag gcgtggcgcg ttatgaagat ttgattacct atgtcaaaga
     3001 ccgccccggc catgatgtgc gctatgcgat tgatgccgca aaaatcggcc gtgagttggg
     3061 ttggcagccg caagaaactt ttgaaagcgg catccgcaaa acagtggaat ggtatttaaa
     3121 caatcaaact tggtggtcgc gcgtgttaga cggcagctac aatcgtgaac gcttaggcag
     3181 ttaaatagag acctttgcaa actccccatc tttggcacat ttcttcgtta tgcgctgctc
     3241 gaaagcttgc ctatctttgt gatatgtctg cgctttctgc gctgctataa cttcgaactg
     3301 tactcaaatc tgtggctttg caaaggcctc aaataataaa aatacgttca gacggcatga
     3361 aggccgcctg aaaaactaca taaggaaagt aaactgatga aaggcattat tctcgcaggc
     3421 ggcagcggta tccgccttta cccgattacc cgcggcgtat caaagcaatt actaccggtg
     3481 tacaacaaac cgatgattta ttaccccttg tcggtgttga tgttggccgg aatccgcgat
     3541 gtgctggtga ttaccacccc cgaagacaac gatgctttcc gccgcttact gggtgatggc
     3601 agcgatttcg gtattcaaat ttcctacgcc atccaaccca gccccgatgg tttggcgcaa
     3661 gcctttttaa ttggtgaaga atttatcggc gatgattcgg tgtgtttggt gttgggcgac
     3721 aatattttct atggccagca tttcagccaa tccctgaaag aagccgccgc ttccgtggaa
     3781 accaaaggtg ctaccgtatt cggctatcaa gtgaaagatc ccgagcgttt cggtgtgatt
     3841 gagtttgatg agaatttcaa agccctgtca atcgaagaaa aaccgaaaca acctaaatcc
     3901 gattgggcgg taaccggcct ctatttctac gataatcgcg tagtcgagtt tgccaaacaa
     3961 gtgaagccgt ctgaacgcgg cgaattggaa attaccacct tgaatcaaat gtatttggac
     4021 gatggttcgc tcaatgtcca attgctcggt cgcggtttcg catggcttga taccggcaca
     4081 cacgccagcc tgttggaagc agcctcgttt gtcgaaacca ttgaaaacat tcaaaaccta
     4141 caagtcgcct gtttggaaga aatcgcatgg cgtaatggct ggttgagcag cgaagaaatc
     4201 agaaacttgg caaagccaat gtgtaaaaat gaatatggcc gctatttatt gcgcttggtt
     4261 ggcaaagatt aagaggttgc ttttaccagt tttcaggccg tctgaaacgc tttttaggaa
     4321 aacatgatga atatcatcga tacccgcatt cccgatgtca aattgctcga acccaaagtc
     4381 ttcggtgacg agcgtggttt ttttatggaa accttccgtg atgaatggtt ccgccaaaat
     4441 gtagccgagc gcactttcgt gcaggaaaac cacagcaaat ccacccaagg cgtattacgc
     4501 ggtttacatt atcaaaccga aaatacacaa ggcaaactgg tgcgcgtggt atcaggcgaa
     4561 gtctttgatg ttgccgtgga tatgcgtcgt gatagtccta ctttcggcca ctgggtcggt
     4621 gaggttttat cggcagacaa caaacgccaa ttatgggtgc cggaagggtt tgcccatgga
     4681 ttttatgtgt tgagcgatga agcggaattc gtctacaaat gcaccgacta ttacaacccg
     4741 aatgcggaac attccctaat ttggaatgat gccacagtgg gaatcgactg gcctttattg
     4801 ggagaaccaa gcctatcggc caaggatttg gcaggcaaga tgcttgctga agcggccaca
     4861 ttttaatttt cacttttagg tcatcgtggg taatttgtag caagatgacc taatttttac
     4921 cagctagcct actaactaaa tttctactat atttaaatag tcagaaaatt tacacaaaat
     4981 ctgttaataa gatattatat tgtcagtaat attttttcct atttattgtg attcctgcct
     5041 acattcctct tcgctctttc ggtatacgta aaattccgaa tattacgcaa tttctaccgg
     5101 aatattcact taacaaaacc gtattcaacg cccaaaccat cattggctgg ggcttacgcc
     5161 cgaccaccca ccaagcacgt gcttttgcac aatcacatgg cttgccgttt gtagccttgg
     5221 aagacggttt tttacgctca ctgggcttag gcgtggccgg ttatccgccc ttcgcactgg
     5281 tttacgacga tatcggcatc tattacgaca caacccgccc atcgcgtttg gagcagttga
     5341 ttttagccgc aaacatgccg tctgaaatgc ttaaccaagc gcagcaggcc attgatttga
     5401 ttttgacgca ccgtttgtct aaatataacc atgctctgga tttttcagac ggcctcgtac
     5461 aagacagcaa aaacattgtt ttggtaattg atcaaacttt cggcgatatg gcgattcaat
     5521 atggcggcgc agatgaagcc acattccgcc aaatgtttca gacggcctta gccgaaaatc
     5581 ctgatgcgga aatctgggtc aaaacccatc ccgatgtatt gagcggcaag aaacagggtt
     5641 accttactga tttggcacag cagccgcgtg tgcgtttatt ggctgaagac attaatccga
     5701 tttcgctgct gcaagcggtg gacaaagtgt attgcgtgac ctcgcaaatg ggttttgaag
     5761 ccttgttgtg cggcaagcct ttggtaacgt ttggtttgcc gtggtatgcc ggctggggtg
     5821 taagcgacga ccgccatcct gaaatcaacc gccttgttca aacccaacgc cgcgccaccc
     5881 gcaacttgct gcagctcttc gccgcagcct atctgcaata cagccgctac ctcaacccca
     5941 ataccggcga agcaggcagc ctctttgatg tcatcgacta tctggcgacg gtcaaacgta
     6001 aaaacgacaa attgcgtggc gagttatatt gcgtcggtat gtctttgtgg aaacgcgcgg
     6061 ttgccaaacc gttctttaac gtaccctctt gccgtctgaa atttatctct tccacccaaa
     6121 aactggcaag ggtcaaactg tccgacgatg cacgcatcct ggcttggggc aacggcaaag
     6181 aggccatcgt ccgctttgcc gaacaacacc acatccccct gctgcgcatg gaagacggct
     6241 ttatccgctc ggtcggactc ggctccaact tagtgccgcc gctgtcgctc gttaccgacg
     6301 atatgagcat ttatttcaat gccgaaaccc cgtcccgtct tgaatacatc ctacaaaacc
     6361 aaaacttcga cgatcaagac tttcagacgg ccttgaagct gcaaaaaatg ctgaccgaaa
     6421 accacatcag taaatacaac gtcggcagct cagacttcac cgccccgtca accgacaaaa
     6481 ccgtgatcct cgttcccggc caggttgaag atgatgcgtc tatccgctac ggttcgcccc
     6541 aaatctaccg caatctggat ttgctccgta ccgtacgcga acgaaacccc aatgcctata
     6601 tcatctacaa accgcatccc gatgtagtca gcggtaaccg catcggccat atttcccctg
     6661 aagatgctgc acgatatgcc gaccaaaccg ccgaacaagc cgacatcctg acctgtctcc
     6721 aatacgcaga cgaaatacat accatgactt cgctgaccgg ttttgaagcc ttgttgcgcg
     6781 gcaaaaaagt cagctgctac ggcctgcctt tttacgcagg ctgggggctt acccaagatc
     6841 tgctccccat cccgcgccgt agccgcagac ttgagctttg gcagctgatt gccggcacgc
     6901 tcatccacta tcccgactac atccaccccg aaacccatca ggccataaat gcagaaaccg
     6961 cagcccaaat cctgatacga caaaaaaata tgcaaaaaaa caacaacgga ttacatcgcg
     7021 ggtgctttgc caaaaaatta ggtaaaatca aacaactata tcgatctttc aaataaatac
     7081 catcaaagtt aacgatgcgt cataaacttg cctctattgc ggcatcattg cctttgcatc
     7141 gttaattctc ttggcgtatg cttgaaagtt caacctaaaa ctattacata aaaaacaaaa
     7201 ccacattgca acatgaaaca gaccgtcctc aaaaataacc tgcaaaacct gcttgaaagc
     7261 gcagaaaata tcctgctgct tcaaggccct gtcggcgatt tttttctgcg ccttgccgac
     7321 tggctgactg caaacggcaa aaccgtacat aaattcaact ttaatgcagg cgacgactat
     7381 ttttatccgc ccactcaggc tcataccgtt gtttttaacg acgactacga tgcttttcct
     7441 gaatttttgc aagaatacat cgttcaatat cacatccggg ccgttgtctg ctttggcgac
     7501 acacgccctt atcacgtcat tgcaaaacgc attgcaaacg aaaaccaagt cggtttctgg
     7561 gcgtttgaag aaggctattt ccgcccctac tacatcacct tagaaaaaga cggcgtcaac
     7621 gcattttccc cgttgccgcg ccgtgccgac ttttttcttg aacaattccc taagcttgcc
     7681 cagcaagaat ataaagcgcc aacgccggta cgcgtcggat ttacgcccat ggcaaaaaac
     7741 gccatccgtt actatatcga gttgttccgc aatctacgca aataccccga ctacatccac
     7801 caccgcgcac ccaatgccgg ccattacctc aaaccgtggt cgctctccat cctcaagcgt
     7861 ttgaactact atattgaaga catccaaatc gccaaacgtg tggaagcagg caaatacggc
     7921 aagtttttta ttgttccctt gcaggtattc aacgacagcc aagtccgtat ccattgcgac
     7981 tttcccagcg tccgcagctt cctgctccat gttttgagtt catttgccga gcacgcgcct
     8041 gccgatacca acatcatcat caagcatcat ccgatggacc gcggttttat cgactactgg
     8101 cgcgacatta aacgctttat caaagaacac cccgaactcc aaggccgtgt gatttatgtc
     8161 catgatgtcc ccctgcccgt tttcctgcgc cacggtctcg gcatggttac catcaacagc
     8221 accagcggcc tgtccggact gattcacaat atgccagtta aggttctcgg ccgtgcctat
     8281 tatgatattc ccggtattac tgaccaaaat accttggcag aattttggaa tcatccgaca
     8341 ccgcctgaca aagagctgtt ccatgcctac cgaatgtacc acctcaacgt gacccaaatt
     8401 aacggcaact tctacagtca ggtctttttt cctaacaaaa acacatccga ctcttccaca
     8461 ccaacaacct aacttggcga aagaaaagct caggccgtct gaaatatttt tcagacggcc
     8521 tgaagcaatc aataccttag ctactgccat gtaaataaaa cacaaaaacc tgcatttatc
     8581 attaacaata aattacaaaa acagtataat gaccgagctg tcatgagcgc ataccgactc
     8641 aacctgagcc ctttgtaaca cacaaaatat ggatgtatcc ctaggcaaaa caatataaca
     8701 agccaaacat cctaaagata agccggcaag gcaacacact ctacaaaacc gtgccaagca
     8761 atatttttac aaagccctca accggtatcg ccgcccatat gccgcagcat ccgtcttcca
     8821 ctttatatcc gcccgcaaac catgaccgcc gctcctgaca tcctctaccg gcaagccgcc
     8881 gcccttttgg aacaatccaa taccgcccaa gccctgcccc tgctgcaaca ggccgcagag
     8941 cagggatata cggaagctgc ttttgtattg ggcgaccatc tgctgcaaaa cggtcatccg
     9001 gagcaggcac ttccatggtt ggaagccgcc gcggcccaac gccatcccaa ggcactcttt
     9061 atcctgctgc aacaacgcgc acacaacggc accccgaccg gacagcttct taacgaatac
     9121 gcctggctga gtgagcaagg tcacctcgaa gcccaattaa ttctcatgcg ttaccacacg
     9181 cagcgcaacg atccacaatc gctctactgg gcggagcttg ccgctgcccg atatgccgca
     9241 cctgcgtatt accatttggc acgccatcat caacgccaag gcgacgttgc aacagctatc
     9301 gaacaatacg aaaaagcggc agcgctcggc gtgactgcag cctgctggca actcggtcaa
     9361 atctacttct acggcacagg tgtcagcccc aaccacacac aagccgaaca ctatctcgaa
     9421 caagccgcgc aagccggcca catcgccgca caaaccctgc tggccgacct tcttgctgcc
     9481 caacgcaaac ccgaagcctt agaatggtat cgtcgtgccg ccgacaaaga gcaagcggaa
     9541 gcacaggcca agctggccca atacgccctg accggcgaac tttccgaacg cgatccgttt
     9601 caagcggcac gatatgccaa agccgctgcc gagaaaaacc atcctgaagc cctgaaaatc
     9661 atgggcgacc tctaccgcta cggtctcggt atcaaagccg acaaccatat cgcgcaagat
     9721 tactaccacc gtgccgccgc gctgggttct gccgccgcag cacaaaaact catcagcgac
     9781 gccgcgctgt accatccgca acaatacgaa caaatcaaaa ctgccgccct gcaacaacaa
     9841 caaaccgaaa ccatctaccg tttggcggaa gcacaagcct gcgccatcgg ccgtcccgcc
     9901 gactacaatg ccgcgcgaaa aaattacatg gaagctgccg ggttccacca taaaaacgca
     9961 gcggcagcct taggccgcat ctaccattac ggcctcggta cggcgcaaga tcctcgggcg
    10021 gctgcacact ggtacgccat cgctgccgaa caaaaccacc cttccgccca ataccacctc
    10081 gcctgttttt actatcacgg acaaggtgtc ggctgtcatg ttccgaccgc ctgctactgg
    10141 ctgcaggctg ccatcagcaa cggccacact tcggccgaat cattaatatc cctattagaa
    10201 caatggcgac gcgaagcaca ccatgccatc ggacaaaagg ccgtctgaaa agatttacac
    10261 tcgcattttt tgacaatctt taactattcc cctaatattt gccagttatt tttcacggac
    10321 acgccattgt tttcatttct ttctgaaaac accttgtccg cgcatcaata ccatgacact
    10381 cggcggataa cgccaagcgt tgaaacacac tacatccgga acaaaaacgg atgctcggaa
    10441 aaatatttct aggaggtgaa acaacatgga atgggaattc aacagttatt acacactgat
    10501 tgccgccacg ctcgtgttgc tggttggtaa atttctggtt caaaaaatca aattcttacg
    10561 agacttcaat attcccgagc cggtcgctgg cggtttggtt gccgcgatta tcctgtttgc
    10621 gctgcacgag gcgtacggcg tgagcttcaa atttgagaaa ccgctgcaaa atgcgtttat
    10681 gctgattttc ttcacgtcca tcggcttgag cgcggatttt tcccgtttga aggcgggcgg
    10741 tttgccgcta gtggttttta ccgcgattgt gggcggattt atcttggtgc aaaactttgt
    10801 cggggtcgga ctggctacgg ctttgggttt ggacccgctc atcggtctga ttaccggttc
    10861 ggtgtcgctg acgggcggac acggtacgtc aggtgcgtgg ggacctaatt ttgaaacgca
    10921 atacggcttg gtcggcgcaa ccggtttggg tattgcatcg gctactttcg ggctggtgtt
    10981 cggcggcctg atcggtgggc cggttgcgcg ccgcctgatc aacaaaatgg gccgcaaacc
    11041 ggttgaaaac aaaaaacagg atcaggacga caacgcggac gacgtgttcg agcaggcaaa
    11101 acgcacccgc ctgattacgg cggaatctgc cgttgaaacg cttgccatgt ttgccgcgtg
    11161 tttggcgttt gccgagatta tggacggctt cgacaaagaa tatctgttcg acctgcccaa
    11221 attcgtgtgg tgtctgtttg gcggcgtggt catccgcaac atcctcactg ccgcattcaa
    11281 ggtcaatatg ttcgaccgcg ccatcgatgt gttcggcaat gcttcgcttt cgcttttctt
    11341 ggcaatggcg ttgctgaatt tgaaactgtg ggagctgacc ggtttggcgg ggcctgtaac
    11401 cgtgattctt gccgtacaaa ccgtggtgat ggttttgtac gcgacttttg ttacctatgt
    11461 ctttatgggg cgcgactatg atgcggcagt attggctgcc ggccattgcg gtttcggctt
    11521 gggtgcaacg ccgacggcgg tggcaaatat gcagtccgtc acgcatactt tcggcgcgtc
    11581 gcataaggcg tttttgattg tgcctatggt cggcgcgttc ttcgtcgatt tgattaatgc
    11641 cgcgattctc accggttttg tgaatttctt taaaggctga ttttccgcct ttccgacaaa
    11701 gcacctgcaa ggtttaccgc ctgcaggtgc ttttgctatg atagccgcta tcggtctgca
    11761 ccgtttggaa ggaacatcat gtatcggaaa ctcattgcgc tgccgtttgc cctgctgctt
    11821 gccgcttgcg gcagggaaga accgcccaag gcattggaat gcgccaaccc cgccgtgttg
    11881 caaggcatac gcggcaatat tcaggaaacg ctcacgcagg aagcgcgttc tttcgcgcgc
    11941 gaagacggca ggcagtttgt cgatgccgac aaaattatcg ccgccgccta cggtttggcg
    12001 ttttctttgg aacacgcttc ggaaacgcag gaaggcgggc gcacgttctg tatcgccgat
    12061 ttgaacatta ccgtgccgtc tgaaacgctt gccgatgcca aggcaaacag ccccctgctg
    12121 tacggggaaa ccgctttgtc ggatattgtg cggcagaaga cgggcggcaa tgtcgagttt
    12181 aaagacggcg tattgacggc agccgtccgc ttcctgcccg tcaaagacgg tcagacggca
    12241 tttgtcgaca acacggtcgg tatggcggcg caaacgctgt ctgtcgcgtt gctgccttac
    12301 ggcgtgaaga gcatcgtgat gatagacggc aaggcggtga aaaaagaaga cgcggtcagg
    12361 attttgagcg gaaaagcccg tgaagaagaa ccgtccaaac ccacgcccga agacattttg
    12421 gaacacaatg ccgccggcgg cgatgcgggc gtaccccaag ccgcagaagg cgcgcccgaa
    12481 ccggaaatcc tgcatcctga cgacggcgag cgtgccgata ccgttaccgt atcacggggc
    12541 gaagtggaag aggcgcgcgt acaaaaccag cgtgcggaat ccgaaattac caaactttgg
    12601 ggaggactcg ataccgacgt gcaaaaagag ttggtcggcg aacaacgcaa gtgggcgcag
    12661 gaaaaaatca gcaactgccg acaagccgcc gcgcaggcag accggcagga atacgccgaa
    12721 tacctcaagc tgcaatgcga cacgcggatg acgcgcgaac ggatacagta tcttcgcggc
    12781 tattccatcg attaggggca aaccgatgac taccgtcccc aaaagcagga ttcccgtcaa
    12841 accgctgccc gaaaaaacca cagacgaagc caaagtcgaa aaatggcggc agctcggtgc
    12901 ggaacacggt ttgtcgggcg aatgggcagt tgccgccaga ttgggcgaga acggttttac
    12961 cgaagaacag atggaaaata tcgccaacct gttcggcaga taaagggaaa attgacggaa
    13021 atgccgtctg aaaccctgtt atcggtttca gacggcattt tgactaatac ggtacgcagg
    13081 cgcaaaacag ccggcttttc ctgtgttgcc tatgctgatg tttcaacacg caggacgata
    13141 tataaagcgt tgccctatgt gccgtcctga ttcggaaagg gttacgcccc tcc
//
LOCUS       DAXISH010000057        12829 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.057, whole genome shotgun sequence.
ACCESSION   DAXISH010000057 DAXISH010000000
VERSION     DAXISH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12829
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.057"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(649..1701)
                     /locus_tag="ACFOV4_001662"
     CDS             complement(649..1701)
                     /locus_tag="ACFOV4_001662"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC7619630.1"
                     /translation="MKIKALMIAAALLAAADVHAAPQKAKTASAKVAKVAKVAKVAKV
                     AKVAKVAKVAATAQKEAAPAQQQGGIRFSDGIAAVADNEVITRRRLAEAVAEAKANLP
                     KEAQISESELSRQVLMQLVNQSLIVQAGKRRNIQASEAEIDAVVAKNSALKNLSPAQR
                     RDFADNIIAEKVRQQAVMQNSRVSEAEIDAFLEQAQKQGITLPEGAPLRQYRAQHILI
                     KADSENAAVGAESTIRKIYGEARSGTDFSSLARQYSQDASAGNGGDLGWFADGVMVPA
                     FEEAVHALKPGQVGAPVRTQFGWHIIKLNEVRDAGTPQERIRNSVRQYIFQQKAEQAT
                     VNLLRDLHSGAYVDIR"
     gene            complement(1806..4214)
                     /locus_tag="ACFOV4_001663"
     CDS             complement(1806..4214)
                     /locus_tag="ACFOV4_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS-assembly protein LptD"
                     /protein_id="HFC7619631.1"
                     /translation="MARLFSLKPLVLALGLCFGTHCAAADAVAAEETDNPTAGGSVRS
                     VSEPIQPTSLSLGSTCLFCSNESGSPERTEAAVRGSGEASIPEDYTRIVADKVEGQSQ
                     VQVRAEGNVVVERNRTTLNTDWADYDQSGDTVTAGDRFALQQDGTLIRGETLTYNLEQ
                     QTGEAHNVRMETEQGGRRLQSVSRTAEMLGEGHYKLTETQFNTCSAGDAGWYVKAASV
                     EADREKGIGVAKHAAFVFGGVPLFYTPWADFPLDGNRKSGLLVPSLSAGSDGVSLSVP
                     YYFNLAPNLDATFAPGVIGERGAVFDGQVRYLRPDYAGQSDLTWLPHDKKSGRNNRYQ
                     AKWQHRHDISDTLQAGVDFNQVSDSGYYRDFYGNKEIAGNVNLNRRVWLDYGGRAAGG
                     SLNAGLSVLKYQTLANQSGYKDKPYALMPRLSADWRKNTGRAQIGVSAQFTRFSHDSR
                     QDGSRLVVYPDIKWDFSNSWGYVRPKLGLHATYYSLNRFGSQEARRVSRTLPIVNIDS
                     GATFERNTRMFGGGVLQTLEPRLFYNYIPAKSQNDLPNFDSSESSFGYGQLFRENLYY
                     GNDRINTANSLSAAVQSRILDGATGEERFRAGIGQKFYFKDDAVMLDGSVGKKPRNRS
                     DWVAFASGSIGSRFILDSSIHYNQNDKRAENYAVGASYRPAQGKVLNARYKYGRNEKI
                     YLKSDGSYFYDKLSQLDLSAQWPLTRNLSAVVRYNYGFEAKKPIEVLAGAEYKSSCGC
                     WGAGVYAQRYVTGENTYKNAVFFSLQLKDLSSVGRNPADRMDVAVPGYIPAHSLSAGR
                     NKRP"
     gene            4284..5288
                     /gene="amgK"
                     /locus_tag="ACFOV4_001664"
     CDS             4284..5288
                     /gene="amgK"
                     /locus_tag="ACFOV4_001664"
                     /EC_number="2.7.1.221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramate/N-acetylglucosamine kinase
                     AmgK"
                     /protein_id="HFC7619632.1"
                     /translation="MQRQIKLKNWLQTVYPERDFDLTFAAADADFRRYFRATFSDGGS
                     VVCMDAPPDKMSVAPYLKVQKLFDMVNVPQVLHADTDLGFVVLNDLGNTTFLTAMLQE
                     QGETAHKALLLEAIGELVELQKASREGVLPEYDRETMLREINLFPEWFVAKELGRELT
                     FKQRQLWQQTVDTLLPPLLAQPKVYVHRDFIVRNLMLTRGRPGVLDFQDALYGPISYD
                     LVSLLRDAFIEWEEEFVLDLVIRYWEKARAAGLPVPEAFDEFYRWFEWMGVQRHLKVA
                     GIFARLYYRDGKDKYRPEIPRFLNYLRRVSRRYAELAPLYALLVELVGDEELETGFTF
                     "
     gene            complement(5345..6043)
                     /locus_tag="ACFOV4_001665"
     CDS             complement(5345..6043)
                     /locus_tag="ACFOV4_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HFC7619633.1"
                     /translation="MKSRHLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGL
                     VEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAHLEPVLSKHAKSFKDDMYLRTEH
                     VVWQKEMLTLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
                     FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMHTID
                     LLADKVREEQKAAQ"
     gene            6070..6261
                     /locus_tag="ACFOV4_001666"
     CDS             6070..6261
                     /locus_tag="ACFOV4_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619634.1"
                     /translation="MLEINRNPAILLHFRVLIQFAAGKGSFRFGKPLQTASNPMPSEA
                     VSVVQYAPLPQTGTTVEEQ"
     gene            6261..7799
                     /gene="murJ"
                     /locus_tag="ACFOV4_001667"
     CDS             6261..7799
                     /gene="murJ"
                     /locus_tag="ACFOV4_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HFC7619635.1"
                     /translation="MNMLGALAKVGSLTMVSRVLGFVRDTVIARAFGAGMATDAFFVA
                     FKLPNLLRRVFAEGAFAQAFVPILAEYKETRSKEATEAFIRHVAGMLSFVLVIVTALG
                     ILAAPWVIYVSAPGFAKDADKFQLSIDLLRITFPYILLISLSSFVGSVLNSYHKFGIP
                     AFTPTFLNVSFIVFALFFVPYFDPPVTALAWAVFVGGILQLGFQLPWLAKLGFLKLPK
                     LSFKDAAVNRVMKQMAPAILGVSVAQISLVINTIFASYLQSGSVSWMYYADRMMELPG
                     GVLGAALGTILLPTLSKHSANQDTEQFSALLDWGLRLCMLLTLPAAVGLAVLSFPLVA
                     TLFMYREFTLFDAQMTQHALIAYSFGLIGLIMIKVLAPGFYARQNIKTPVKIAIFTLI
                     CTQLMNLAFIGPLKHVGLSLAIGLGACINAGLLFYLLRRHGIYQPGKGWAAFLAKMLL
                     SLAVMGGGLYAAQIWLPFDWAHAGGMQKAARLFILIAVGGGLYFASLAALGFRPRHFK
                     RVES"
     gene            7932..8888
                     /locus_tag="ACFOV4_001668"
     CDS             7932..8888
                     /locus_tag="ACFOV4_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheT family hydrolase"
                     /protein_id="HFC7619636.1"
                     /translation="MILTPPDTPFFLRNGNADTIAAKFLQRPAPAYRRELLPDSTGKT
                     KVAYDFSDGISPDAPLVVLFHGLEGSSRSHYAVELMLAVRSRGWHGAVVHFRSCGGIA
                     NTAPVFYHLGDTAEIAFTLDTLAARYREIYAVGVSLGGNALAKYLGERGENALPQAAA
                     AVSAPVDAEAAGRRFDSGITRLLYTRYFLRTLIPKARSLHGFQTAFAAGCKTLGEFDD
                     RFTAPLHGFADRHDYYRQTSCKPLLKHVAKPLLLLNAANDPFLPPEALPTPDEVSEAV
                     TLFQPAHGGHAGFVGSTGGRLHLQWLPQTVLSYFDSFRTNRR"
     gene            8939..9721
                     /gene="trpC"
                     /locus_tag="ACFOV4_001669"
     CDS             8939..9721
                     /gene="trpC"
                     /locus_tag="ACFOV4_001669"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HFC7619637.1"
                     /translation="MTDILNKILTAKAQEVAAQKAAVNAEHIRALAAEAVPVRSFIDS
                     IRGKHRLNLPAVIAEIKKASPSKGLIRPDFRPAEIARAYENAGAACLSVLTDEPYFQG
                     SPEYLKQAREAVSLPVLRKDFIIDEYQVYQARAWGADAVLLIAAALEQEQLERFEAVA
                     HELGMTVLLELHDETELEKCRNLTTPLWGVNNRNLRTFEVSLDQTLSLLPALEGKTVV
                     TESGITGKADVEFMQSRGVHTFLIGETFMRADDIEAEVGKLF"
     gene            9787..12087
                     /gene="recQ"
                     /locus_tag="ACFOV4_001670"
     CDS             9787..12087
                     /gene="recQ"
                     /locus_tag="ACFOV4_001670"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFC7619638.1"
                     /translation="MHRPTAKQILHEVFGYPEFRGKQEAIVNALAVGESLMVLMPTGG
                     GKSLCYQIPALMREGVAVVVSPLIALMNDQVASLHVAGIEAAAVNSGTSADEAREIAD
                     KLAQGRLKLLYVAPERLVTDRFLRFLDQQTVSLFAIDEAHCVSQWGHDFRPEYQQLGM
                     LAERYPNVPRIALTATADAATRADIKHYLHLDDAPEFISSFDRPNIYYQVIEKNNGKK
                     QLLEFIRKEMTGQSGIVYCLSRKKVEDVAQFLRENGLNAIPYHAGLSMDVREENQRRF
                     TREDNIIVVATVAFGMGIDKPDVRFVAHLDMPQSVEHFYQESGRAGRDGLPAASWLCY
                     GLNDWVLLRERIAEGNSGEVQKQIEMQKLDAMLAVCETAACRRVLLLKHFGEASEPCG
                     RCDNCLHPPVRFDGTVLVQKLLSCVYRAGQRFAAGYITNLLRGKSDDWIRGNRHEQLS
                     TFGIGAELSDKEWRSVIRQCISLGYLTVNIARYQALQLTEAAKKVLKGETEVMLRPLK
                     RDKPAARTLKDNWLRTEREERLWQALRVWRMKQAEAEVIPAYMIFGDKTLRDLVEKMP
                     QDLNGLHDIYGLGEAKIDRFGHGILEVCRNTAGFSRDAVIRPQTEREQQLRQKLEAWR
                     YEQARAENCALHAVLSDESLADMLAATPETETDLEGVHGLGSVRAAKYGRDILAVCRP
                     FSDGIDEAAKRKRRLMRALIQWCGETAKHEQSEPYRILSKAALRAIAAKQPKGLAELA
                     AVYGVGEEKTARYGAAVLAVLGQNAV"
     gene            complement(12230..12655)
                     /locus_tag="ACFOV4_001671"
     CDS             complement(12230..12655)
                     /locus_tag="ACFOV4_001671"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619639.1"
                     /translation="MYWERGLHMYKASAVVPTGYVRVGNTAPLVGEDTQRYASFWGDG
                     YDVYRQLRWQQIPEKQRKAFKKAAKSKKTVMFAGREYGISKQNLSDVWDDFEDAMELK
                     AFPCLSSLFLTKWHKNLYDSGLTKTSTALSRLSSKRTIL"
BASE COUNT         2617 a         3569 c         3641 g         3002 t
ORIGIN      
        1 atcccgtcat tcccgtaaaa gcgggaatcc ggctcgttcg gtttcagttt tttaggtttc
       61 aggcaacttc tgaatcgtca ttcccacaca ggtgggaatc taggtctgtc cgcacgggaa
      121 cttatgcgcc gtcattcccg cgaaagcggg aatccagacc gttcggcttc agttttttga
      181 tttcgggcaa cttctgaatc gtcattccca cgcatgtggg aatctaggtc tgtccgcacg
      241 ggaacttatg cgccgtcatt cccgtaaaag cgggaatcca gaccgttcgg cttcagtttt
      301 ttggtttcgg gcaacttctg aatcgtcatt cccacgcatg tgggaatcta ggtctgtccg
      361 cacgggaact tatgcgccgt cattcccgcg aaagcgggaa tccagattct tcggtacaga
      421 aacttatcgg ataaaacggt ttctttagat tctacgtcct agattcccgc ctgcgcggga
      481 atgacggcat agaggtttct gttttcccga taaattcctg ttacttttcg ttgctagatt
      541 cccgcctacg cgggaatgat gaatgacggt gtaaaagtaa ctcgaaatcc aaaaagccat
      601 accgcccgga tttttgccga tcggtatggc tttttgcttc aaaccgcctt agcggatgtc
      661 gacatacgcg ccggaatgca ggtcacgcaa caggttgacg gttgcctgtt cggctttttg
      721 ttggaagatg tattgccgca cggaattgcg gatacgttcc tgaggtgtgc cggcatcgcg
      781 cacttcgttc aatttgatga tatgccagcc gaattgggtg cggacgggcg cgccgacctg
      841 tccgggtttg agcgcgtgga cggcttcttc aaaggcggga accatcacgc cgtcggcaaa
      901 ccagcccaaa tctccgccgt tgcccgcgct cgcgtcttgc gaatattggc gcgctaggct
      961 ggaaaagtct gtgccgctgc gggcctctcc gtagattttg cggatggtgc tttccgcgcc
     1021 gacggcggcg ttttcgctgt cggctttaat caggatgtgt tgggcgcggt attggcgcaa
     1081 cggtgcgcct tcgggcaggg tgatgccttg tttttgcgcc tgctcgagga aggcatcgat
     1141 ttcagcttcg ctcacgcggc tgttctgcat cactgcctgc tggcggactt tttcggcaat
     1201 gatgttgtcg gcaaaatcgc ggcgttgggc ggggctgagg tttttgaggg cggaattttt
     1261 tgcgacgacg gcatcgattt ccgcttcgct tgcttgaatg ttgcggcgtt tgcccgcctg
     1321 tacaatcagg gattggttga caagctgcat cagcacctgt cgggacagct cggattcgct
     1381 tatctgcgcc tctttgggca ggttggcttt ggcttcggca acggcttcgg caagccggcg
     1441 gcgcgtgatg acttcgttgt cggcaacggc ggcaatgccg tctgaaaagc ggataccgcc
     1501 ctgctgttgt gcgggtgcgg cttctttttg cgccgtggcg gcaactttgg caactttggc
     1561 aactttggca actttggcaa ctttggcaac tttggcaact ttggcaactt tggcggatgc
     1621 ggtttttgcc ttttgcggtg cggcgtggac atcggctgct gccagcaatg cggcggcaat
     1681 catcagggct ttgattttca tcattctttc cttatcgttt gaatcctacc tttgatggcg
     1741 ggtttggggt tgtcggtgga atgccgtctt gtgcgggaac ggtgctcctg ccgggtttcc
     1801 gacggtcagg gtcgtttgtt gcgtccggcg gaaagagagt gggcggggat gtagccggga
     1861 acggcgacat ccatcctgtc tgcggggttt ctgccgacac tgctgaggtc tttcaactga
     1921 agtgagaaaa agacagcgtt tttgtaggtg ttttcgccgg taacgtagcg ttgggcgtac
     1981 acgcccgcgc cccagcagcc gcaactgctt ttgtattccg cacccgccag cacctctatc
     2041 ggttttttgg cttcaaaacc gtagttgtaa cggacgacgg ccgacaggtt gcgcgtcagc
     2101 ggccattgtg cggacaggtc gagctggctg agtttgtcgt aaaaatagga accgtcggac
     2161 ttcaggtaga ttttttcgtt gcgcccgtat ttgtagcggg cgttcagcac tttgccctgt
     2221 gcgggacggt agcttgcacc gacggcgtag ttctcggcgc gtttgtcgtt ttggttgtag
     2281 tggatgctgc tgtcgaggat gaagcggctg ccgatgctgc cggaggcaaa tgccacccag
     2341 tcggaacggt tgcgcggttt tttgccgacg ctgccgtcaa gcatcaccgc atcatccttg
     2401 aaatagaatt tctgaccgat gccggcgcgg aaacgctctt cccccgtcgc gccgtccaaa
     2461 atacggcttt gcacggcggc ggaaaggctg tttgcggtgt taatcctgtc gttgccgtaa
     2521 tagaggtttt cgcgaaagag ctgcccgtag ccgaagctgc tttccgacga atcgaaattg
     2581 ggcaggtcgt tttgggattt ggcaggaata tagttgtaga acaggcgcgg ctcgagggtt
     2641 tgcaggactc cgccgccgaa catccgcgta ttccgctcaa aagttgcgcc gctgtcgatg
     2701 ttgacaatgg gcagagtgcg gctgacgcgt cgggcttctt ggctgccgaa gcggttgagg
     2761 ctgtaatagg tggcgtgcag tccgagtttg ggacggacgt aaccccagct gttgctgaaa
     2821 tcccatttga tgtcgggata gacgacgagg cggctgccgt cttggcggct gtcgtggctg
     2881 aagcgggtaa attgtgcgga cacgccgatt tgcgccctgc cggtgttttt gcgccaatcg
     2941 gcggaaaggc gcggcatcag ggcatacggt ttgtctttgt agccgctttg gtttgccagc
     3001 gtctggtatt tcagaaccga aaggccggca ttcaggctgc cgcccgccgc cctgccgcca
     3061 taatccagcc atacacggcg gttgaggttg acgttgccgg cgatttcttt gttgccgtaa
     3121 aagtcgcggt agtagccgct gtcggagact tggttgaaat cgacacccgc ctgaagcgtg
     3181 tcggaaatgt cgtgccggtg ctgccatttc gcctgatagc ggttattcct gccgcttttt
     3241 ttgtcgtgcg gcagccaggt caggtcggac tggccggcat aatccggccg caggtagcgt
     3301 acctgcccgt caaagaccgc gccgcgttcg ccgatcacgc cgggcgcgaa cgtggcatcg
     3361 agattggggg caaggttgaa ataataggga acggaaaggg aaacgccgtc cgaaccggcg
     3421 gacagtgagg gaacaagcag gccgcttttg cggttgccgt caagcgggaa gtccgcccaa
     3481 ggcgtataga aaaggggaac gccgccgaac acgaaggcgg cgtgtttggc aacgcctatg
     3541 cctttttccc gatcggcttc gacggaagcg gccttgacat accagccggc atcgccggcg
     3601 gaacaggtgt tgaattgggt ttccgtcagt ttgtaatgcc cttcgcccaa catttcggcg
     3661 gtgcggctga cgctttgcag ccgccgtccg ccttgttcgg tttccatacg gacgttgtgc
     3721 gcttccccgg tctgctgctc gagattgtag gtcagggttt cgccccgaat cagcgtaccg
     3781 tcctgttgga gggcgaaccg gtcgcctgcg gtaacggtgt cgcccgactg gtcgtaatcc
     3841 gcccaatcgg tattgagggt cgtccggttg cgttcgacga cgacgttgcc ttcggcacgc
     3901 acctgcacct gcgactgtcc ttccaccttg tcggcaacaa tgcgcgtata gtcttcgggg
     3961 atggatgctt cgccgctgcc tcggacggcg gcttcggttc tctcggggct gccgctttcg
     4021 ttactgcaaa acaggcaggt cgaaccgagg ctcaggctgg taggctgtat gggttcggac
     4081 acgctccgaa cgcttcctcc ggcggtcgga ttgtccgttt cctccgccgc aacggcatcg
     4141 gcggcggcgc aatgcgtgcc gaagcagagg cccaatgcca gcaccagtgg tttgagtgaa
     4201 aataaacgag ccaaaatcgc ccctcaagtc ggtttgccag ttagaatagc gtttattgta
     4261 acctgaaatg ctttagtact gttatgcaac gacaaatcaa actgaaaaat tggcttcaga
     4321 ccgtttatcc cgaacgggac ttcgatctga cttttgcggc ggcggatgct gatttccgcc
     4381 gctatttccg tgcaacgttt tcagacggcg gcagcgtcgt ctgtatggat gcgccgcccg
     4441 acaagatgag tgtcgcgcct tatttgaagg tgcagaaact gtttgatatg gtcaatgtgc
     4501 cgcaggtatt gcacgcggac acggatttgg ggtttgtggt attgaacgac ttgggcaata
     4561 cgacgttttt gaccgcgatg cttcaggaac agggcgaaac ggcgcacaaa gccctgcttt
     4621 tggaggccat cggcgagttg gtcgaattgc agaaggcaag ccgtgaaggg gttttgcccg
     4681 aatatgaccg tgaaacgatg ctgcgcgaaa tcaacctgtt cccggaatgg tttgtcgcaa
     4741 aagaattggg gcgcgaatta acattcaaac aacgccaact ttggcagcaa accgtcgata
     4801 cgctgctgcc gcccctgttg gcgcagccca aagtctatgt gcaccgcgac tttatcgtcc
     4861 gcaacctgat gctgacgcgc ggcaggccgg gcgttttaga cttccaagac gcgctttacg
     4921 gcccgatttc ctacgatttg gtgtcgctgt tgcgcgatgc ctttatcgaa tgggaagaag
     4981 aatttgtctt ggacttggtt atccgctact gggaaaaggc gcgggctgcc ggcttgcccg
     5041 tccccgaagc gtttgacgag ttttaccgct ggttcgaatg gatgggcgtg cagcggcact
     5101 tgaaggttgc aggcatcttc gcacgcctgt actaccgcga cggcaaagac aaataccgtc
     5161 cggaaatccc gcgtttctta aactatctgc gccgcgtatc gcgccgttat gccgaactcg
     5221 ccccgctcta cgcgctcttg gtcgaactgg tcggcgatga agaactggaa acgggcttta
     5281 cgttttaaac ccaatcaaaa tgccgtctga aaaccaagtt tcagacggca tttttcaaac
     5341 gggcttactg cgcggctttt tgttcttcgc gtactttgtc cgccaaaagg tcgatggtgt
     5401 gcataccgga ctcccagtcg gcaaattcga ctttatattt gccgccgacg ataaccgtgg
     5461 gcgtaccgtc gatttggaag gtttcggtca gctcctgcat tttgtcggcg cgcgcctggc
     5521 tttcggggga ctcgtaggcg gcaaggactt ttttgccgtc aaaggcggtt tgttcgccca
     5581 gccatttttt gaggacttcc ggctcttgca gcttgatttt ttggttgacc atcgcatcga
     5641 aaatatggct gttcgccaca tctttgctgt cggcggcagc catatcgacg gcggcggcga
     5701 ggcgtgcgag cgtcagcatt tctttctgcc agacgacgtg ttcggtacgc aggtacatat
     5761 cgtctttaaa agacttggcg tgtttgctta aaacaggttc gaggtgggcg cagtgcggac
     5821 agaaatagcc gaaaaattca aggacttcga ctttgcctgc ctgctgttgg ggaatcgggt
     5881 tggcaaggac ggtatagttt tgcccttcga ccagccctgc cggggcggcg gctgccgaag
     5941 cggcaggcgc gctgtcggcg gggacgctgg tttggacttt gctgtcgcac gcggcaaggg
     6001 cgaacagggc ggcaacgccg agggcgaggt gtctggattt catacggctc tccgtgatgt
     6061 tggaaacaga tgttggaaat caatcggaat ccggctattt tattgcattt ccgcgtgttg
     6121 atacagtttg ccgccggaaa aggaagcttt cgtttcggga aaccgcttca gacggcatca
     6181 aacccgatgc cgtctgaagc ggtttctgtc gtacaatacg cgccgttgcc ccaaacgggt
     6241 acgactgttg aggaacaatg atgaatatgc tgggagcttt ggcaaaagtc ggcagcctga
     6301 cgatggtgtc gcgcgttttg ggatttgtgc gcgatacggt cattgcgcgc gcattcggcg
     6361 cgggcatggc gacggatgcg ttttttgtcg cgttcaaact gcccaacctg cttcgccgcg
     6421 tgtttgcgga gggggcgttt gcccaagcgt ttgtgccgat tttggcggaa tataaggaaa
     6481 cgcgttctaa agaggcgacg gaggctttta tccgccatgt ggcggggatg ctgtcgtttg
     6541 tgctggtcat cgttaccgcg ctgggcatac ttgctgcgcc ttgggtgatt tatgtttccg
     6601 cacccggttt tgccaaagat gccgacaaat ttcagctctc catcgatttg ctgcggatta
     6661 cgtttcctta tatcttattg atttcacttt cctcttttgt cggctcggta ctcaattctt
     6721 atcataagtt cggcattccg gcgtttacgc ccacgttcct gaacgtgtcg tttatcgtat
     6781 tcgcgctgtt tttcgtgccg tatttcgatc ctcccgttac cgcgctggct tgggcggtct
     6841 ttgtcggcgg cattttgcag ctcggcttcc aactgccctg gctggcgaaa ctgggttttt
     6901 tgaaactgcc caaactgagt ttcaaagatg cggcggtcaa ccgcgtgatg aaacagatgg
     6961 cgcctgcgat tttgggcgtg agcgtggcgc agatttcttt ggtgatcaac acgattttcg
     7021 cgtcttatct gcaatcgggc agcgtttcat ggatgtatta cgccgaccgc atgatggaac
     7081 tgcccggcgg cgtgctgggg gcggcactcg gtacgatttt gctgccgact ttgtccaaac
     7141 actcggcaaa ccaagatacg gaacagtttt ccgccctgct cgactggggt ttgcgcctgt
     7201 gtatgctgct gacgctgccg gcggcggtcg gactggcggt gttgtcgttc ccgctggtgg
     7261 cgacgctgtt tatgtaccgc gaattcacgc tgtttgacgc gcagatgacg caacacgcgc
     7321 tgattgccta ttctttcggt ttaatcggtt tgatcatgat taaagtgttg gcacccggct
     7381 tctatgcgcg gcaaaacatc aaaacgcccg tcaaaatcgc catcttcacg ctcatctgca
     7441 cgcagttgat gaaccttgcc tttatcggcc cactgaaaca cgtcggactt tcgcttgcca
     7501 tcggtctggg cgcgtgtatc aatgccggat tgttgtttta cctgttgcgc agacacggta
     7561 tttaccaacc tggcaagggt tgggcggcgt tcttagcaaa aatgctgctc tcgctcgccg
     7621 tgatgggagg cggcctgtat gccgcccaaa tctggctgcc gttcgactgg gcacacgccg
     7681 gtggaatgca aaaggccgcc cggctcttca tcctgattgc cgtcggcggc ggactgtatt
     7741 tcgcatctct ggcggctttg ggcttccgtc cgcgccattt caaacgggtg gaaagctgac
     7801 cgatgccgat atcctttttc ggaaaacgct ttttccgcgc ctatattcgg gcgcgcatcc
     7861 cccgcgtccg caccagccgg acgggctgcc gcatcatcaa tgccgtctga aaacagaaaa
     7921 accgatacct tatgattttg acaccgccgg acacaccgtt tttcctccgc aacggcaatg
     7981 ccgatacgat tgccgccaaa ttcctgcaac gccccgcacc cgcataccgc cgcgagctgc
     8041 ttcccgacag cacgggtaaa accaaagtcg cctacgactt ttcagacggc atttcgcccg
     8101 atgcgccgct ggtcgtgctg tttcacggtt tagaaggaag cagccgcagc cattacgcgg
     8161 tcgaactgat gctcgcggta cgcagccgcg gttggcacgg cgcagtcgtc catttccgca
     8221 gctgcggcgg cattgccaac accgctccgg tgttctacca cttgggcgat accgccgaaa
     8281 tcgcctttac tttggacacg cttgccgcgc gttaccgtga aatatacgcc gtcggcgtat
     8341 cgctgggcgg caacgcgctg gcaaaatatt tgggcgaacg gggcgaaaac gcgctgccgc
     8401 aagccgctgc cgccgtatcc gcccccgtcg atgcagaggc ggcaggcaga cgcttcgaca
     8461 gcggcatcac gcggctgctc tacacgcgct acttcctccg caccctgata cccaaagcac
     8521 ggtcgctcca cggttttcag acggcatttg ccgcagggtg caaaacactg ggcgagtttg
     8581 acgaccgctt caccgcaccg ctgcacggct ttgccgaccg gcacgactac taccgccaaa
     8641 cttcctgcaa accgctgctc aaacacgttg ccaaaccgct gctcctgctc aatgccgcca
     8701 acgacccctt cctgccgccc gaagcgctgc cgacaccgga cgaagtgtcc gaagccgtta
     8761 ccctgttcca gccggcacac ggcggacacg ccggctttgt cggcagcacc ggcggcaggc
     8821 tgcacctgca atggctgccg cagaccgtcc tgtcctattt cgacagcttc cgcacaaaca
     8881 ggcggtaacg gtttgatgct aatattcccc ctttccccag acgaatacgg aacccgacat
     8941 gaccgacatc ctcaataaaa tccttaccgc caaggcacag gaagttgccg cccaaaaagc
     9001 cgccgtcaac gccgaacaca tccgcgcact tgccgcagaa gccgtgcccg tccgcagctt
     9061 catcgattcg atacgcggca aacaccgcct aaacctgccc gccgtcattg ccgaaatcaa
     9121 aaaggcaagc ccgagcaaag gcctgatccg tccggacttc cgacctgccg agattgcccg
     9181 cgcctatgaa aacgccgggg cggcgtgttt gtccgtactg accgacgaac cctatttcca
     9241 aggttcgccc gaatacctca aacaggcgcg cgaagccgta tcgctgcccg tgctgcgcaa
     9301 agacttcatc atcgacgaat atcaggttta tcaggcgcgc gcatgggggg cggatgccgt
     9361 cctgctgatt gccgcagcac tggaacagga acaattggaa cgctttgaag cggtggcgca
     9421 cgaattgggc atgaccgtcc tgctcgagct gcacgacgaa accgaattgg aaaaatgccg
     9481 caacctgacc acgccgttgt ggggcgtaaa caaccgcaac ctgaggactt ttgaagtctc
     9541 cctcgaccaa accctgtcgc tgctgcccgc actggaaggc aaaaccgtcg ttaccgaaag
     9601 cggcattacg ggcaaggcgg atgtggaatt tatgcaatcg cgcggcgtgc acaccttcct
     9661 gattggcgaa acgttcatgc gtgccgacga tattgaggcg gaagtgggca aactcttcta
     9721 aatctcgatt tcagacggca tattgccgcc gaccaatcga cacccattac cggacacgga
     9781 accatcatgc accgacccac cgccaaacag attctgcacg aagtattcgg ttatcccgaa
     9841 tttcgcggca agcaggaggc tatcgtcaat gctttggcag tcggcgagag tttgatggtg
     9901 ctgatgccga cgggcggggg caagtctttg tgttaccaga ttccggcgct gatgcgcgaa
     9961 ggcgtggcgg ttgtcgtatc gccgctgatt gcgctgatga acgaccaagt ggccagcctg
    10021 catgtggccg ggattgaagc ggcggcagtc aacagcggca catcggcaga cgaggcgcgc
    10081 gagattgccg acaagcttgc ccaaggccgt ctgaagctgc tttatgtcgc gccggaacgc
    10141 ctagttaccg accgcttttt gcgttttctc gaccaacaaa ccgtcagcct gttcgccatt
    10201 gatgaggcgc attgcgtcag ccaatgggga cacgatttcc gccccgagta ccaacagctc
    10261 ggcatgcttg ccgaacgcta tccgaacgtc ccgcgcatcg ccctgaccgc caccgccgat
    10321 gccgccacgc gcgccgacat caagcattat ctgcacttgg acgatgcgcc cgaatttatc
    10381 tccagctttg accgcccgaa tatttattat caggttatcg aaaaaaataa tggcaaaaaa
    10441 caactgcttg aattcatccg caaagaaatg acggggcaaa gcggcattgt gtattgccta
    10501 agccgcaaaa aagtcgaaga tgtggcgcag tttttgcgtg aaaacggatt aaacgcgatt
    10561 ccgtatcatg ccggtttgag catggacgtg cgcgaggaaa accaacgccg ctttacgcgt
    10621 gaagacaata ttatcgtggt ggcgaccgtg gcgttcggca tgggtataga caaacccgac
    10681 gtgcgctttg tcgcccatct cgatatgccc cagagtgtcg aacatttcta tcaggagtcg
    10741 gggcgcgccg gccgagacgg gctgcctgcc gcgagctggc tgtgttacgg cctgaacgat
    10801 tgggtgttgc tgcgcgaacg catcgccgaa ggcaacagcg gcgaagtgca aaagcaaatc
    10861 gaaatgcaaa aactcgatgc catgcttgcc gtctgcgaaa ccgccgcctg ccgccgcgtg
    10921 ctgctgctca aacatttcgg cgaagcatcc gaaccctgcg gccgttgcga caactgcctg
    10981 catccgcccg tacggtttga cggcacggtg ttggtgcaaa aattactcag ctgcgtgtac
    11041 cgcgccggac aacgttttgc cgccggttac atcaccaacc ttttgcgagg taaaagcgac
    11101 gattggatac gcggcaaccg gcacgaacaa ctgtccacat tcggcatcgg tgcagaattg
    11161 tccgacaaag aatggcgcag cgtcatccgc cagtgcatca gcctcggcta cctcaccgtc
    11221 aacattgccc gatatcaggc attgcaacta accgaagccg ccaaaaaagt cctcaaaggc
    11281 gaaaccgaag tgatgctgcg tccgctcaag cgcgacaagc ccgccgcccg caccctcaaa
    11341 gacaactggc tgcgtaccga acgcgaagaa cgcctgtggc aggcattgcg cgtttggcgt
    11401 atgaaacagg cagaagccga agtcatcccc gcctatatga ttttcggcga caaaaccctg
    11461 cgcgaccttg tcgaaaaaat gccgcaagac ctcaacggac tgcacgacat ctacggtttg
    11521 ggcgaagcca aaatcgaccg tttcggacac ggcatcctcg aagtctgccg caacaccgcc
    11581 ggcttcagtc gcgacgcggt catccgtccg caaaccgaac gcgaacaaca actgcgtcaa
    11641 aaactcgagg cctggcggta tgaacaggca agggcggaaa actgcgccct gcatgccgtc
    11701 ctctccgacg aaagccttgc cgatatgctt gccgccacgc ccgaaaccga aaccgacctc
    11761 gaaggcgtac acggcttggg cagcgtacgc gccgccaaat acggacggga catcctcgcc
    11821 gtctgccgtc cgttttcaga cggcatcgat gaagccgcca aacgcaaacg ccgcctgatg
    11881 cgcgccctga tccaatggtg cggcgaaacg gcaaaacacg aacagtccga accctaccgc
    11941 attctcagca aagccgccct gcgcgccatt gccgccaaac agccgaaggg tttggcggag
    12001 cttgccgccg tatacggcgt gggcgaagaa aaaaccgcac gttacggtgc ggcggtgttg
    12061 gcggtgttgg gacaaaatgc cgtctgaaaa ccgttaccaa gtttcagacg gcattgcctc
    12121 tatttaaaaa ttcctgtttt tatagtggat taacaaaaat caggacaagg cgacgaagcc
    12181 gcagacagta cagatagtac ggaaccgatt cacttggtgc ttcagcacct tagagaatcg
    12241 ttctctttga gctaaggcga gacaacgctg tactggtttt tgttaatcca ctatcatata
    12301 gatttttatg ccatttggtc agaaacagcg aagacaggca gggaaacgcc ttcagttcca
    12361 tcgcgtcttc aaaatcatcc caaacatcgc tcaaattctg tttggatatg ccgtattccc
    12421 gtccggcaaa catcacggtc tttttgcttt tggcggcttt tttgaatgcc tttctctgtt
    12481 tttcgggtat ctgctgccat ctcaactgac ggtacacgtc gtagccgtcg ccccaaaaag
    12541 aggcataccg ttgcgtgtct tcgccgacca gcggcgcggt attcccaacc cgtacatatc
    12601 ccgttggcac gacagcactt gccttataca tgtgcagacc gcgttcccaa tacatattca
    12661 attgaatcgc tcataaattt ttgctccaaa atttaaagtt ttactatagt agaaataaat
    12721 atcaaaactg aaaatattac tgaaaaaatt ttatattgtt taacttttct tttatacgaa
    12781 ttcgcctttg ttgaaattaa ttgataatca aaccagcaag aaataattc
//
LOCUS       DAXISH010000058        12483 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.058, whole genome shotgun sequence.
ACCESSION   DAXISH010000058 DAXISH010000000
VERSION     DAXISH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12483
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.058"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..163
                     /locus_tag="ACFOV4_001672"
     CDS             <1..163
                     /locus_tag="ACFOV4_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC7619640.1"
                     /translation="YVVEQSFGTLHRKFRYARSTYFGLIKVSAQSHLKAMCLNLLKAA
                     NRLSAPAAA"
     gene            complement(494..1423)
                     /locus_tag="ACFOV4_001673"
     CDS             complement(494..1423)
                     /locus_tag="ACFOV4_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFC7619641.1"
                     /translation="MDSIIELRHLKTLLALEETGSVSLAAKRVFLTQSALSHQIRMLE
                     NHYGTPLFERKSTPLRFTPVGERLLRLAHELIPQVAVAEWDLARITEGEAGELRIAVE
                     CHTCFDWLMPAMGEFRPMWPQVELDIVSGFQADPVGLLLQHRADLAIVSEAEKQNDIS
                     FQPLFAYEMVGICAPDHPLAAKNVWTAEDFIGETLITYPVPDEMLDLPKKILIPKNIN
                     PPRRHSELTIAIIQLVASRRGIAALPYWTVMPYLEKGYVVHRQITADGLQSKLYAAIR
                     TEDTDKSYLNNFCQIIRERGFADLPGLSELEPV"
     gene            1554..2303
                     /locus_tag="ACFOV4_001674"
     CDS             1554..2303
                     /locus_tag="ACFOV4_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFC7619642.1"
                     /translation="MVLRRDFLTWCNETLQTALFKDYSPNGLQVEGREYIGKIVTSVT
                     ASRAAIDFAVEQKADLLLVHHGMFWKNELPTVTGWKKERIAALLRHDINMAGYHLPLD
                     AHPTLGNNAQLADRLGFATEKRFGEQNLLNSGSLKQAKTLGALAAHIETVLQRKPVVI
                     GKPEREIRRVAWCSGGAQGFFQTAIDEGVDLYLTGEISEAQYHLANETGTAFISAGHH
                     ATERYGVRALAESAAEVFGLEVCHFDENNPA"
     gene            2426..3007
                     /gene="petA"
                     /locus_tag="ACFOV4_001675"
     CDS             2426..3007
                     /gene="petA"
                     /locus_tag="ACFOV4_001675"
                     /EC_number="7.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045275 - respiratory chain complex III
                     [Evidence IEA];
                     GO_function: GO:0008121 - ubiquinol-cytochrome-c reductase
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0009060 - aerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="HFC7619643.1"
                     /translation="MDNQEINNGRRRFLTLATCGAGGVAALGVATPFVASFFPSEKAK
                     AAGAAVEVDVSKIEAGQLLTAEWQGKPIWVLNRTDQQLKDLKGLNGELTDPNSDAEQQ
                     PEYAKNETRSIKPNILVAIGICTHLGCSPTFRPDIAPADLGADWKGGFFCPCHGSKFD
                     LAGRVYKGVPAPTNLVVPPYKYLSDTTILVGED"
     gene            3026..4375
                     /locus_tag="ACFOV4_001676"
     CDS             3026..4375
                     /locus_tag="ACFOV4_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bc complex cytochrome b subunit"
                     /protein_id="HFC7619644.1"
                     /translation="MANQTNSKAKALLGWMDARFPLSKMWNEHLAQYYAPKNFNFWYY
                     FGSLALLVLVIQIVSGIFLTMNYKPDGNLNAYHLPAAFTAVEYIMRDVSGGWIIRYMH
                     STGASFFFIVVYLHMFRGLIYGSYKKPRELVWIFGSLIFLALMAEAFMGYLLPWGQMS
                     FWGAQVIINLFSAIPVIGPDLSTWIRGDFNVSDVTLNRFFALHVIAVPLVLLGLVVAH
                     IIALHEVGSNNPDGVEIKKNKDENGIPRDGIPFHPYYTVKDILGVVVFLIVFCAVLFF
                     APEGGGYFLEAPNFDAANALKTPPHIAPVWYFTPFYAILRAIPSFLGTQVWGVIGMGA
                     AVVLIALLPWLDRGEVKSVRYRGPIFKTALVLFIISFIGLGILGAMVATDTRTLVARI
                     LSFVYFAFFLGMPFYTKLDKNKPVPERVTMSTAKQKIMFFVYVGITAVGAYLFATNI"
     gene            4390..5178
                     /locus_tag="ACFOV4_001677"
     CDS             4390..5178
                     /locus_tag="ACFOV4_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c1"
                     /protein_id="HFC7619645.1"
                     /translation="MKQAMKNWFAALLLAVPMGAAFASGGHAHYEKVDIDLRDQVSLQ
                     RGAQIFTNYCLSCHSASGMRFNRLKDIGLTDEEIKKNLMFTTDNVGDVMHSAMNPKDA
                     AKWFGAAPPDLTLIARSKGADYLYAYMRGFYKDPTRPSGWNNTVFDKVGMPHPLWEQQ
                     GVQAVELDAKGQPVMVKDEHGEMKPKLYWESTGLHSRRLPNGKVIQKEYDAYVRDLVN
                     YLVYMGEPAQLQRKRIGYVVMIFLFAVMLPLAYFLKKEYWKDVH"
     gene            5517..7307
                     /gene="rmuC"
                     /locus_tag="ACFOV4_001678"
     CDS             5517..7307
                     /gene="rmuC"
                     /locus_tag="ACFOV4_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HFC7619646.1"
                     /translation="MELMTVLLPLAALVSGVLFTWLLMKGRFQGEFADLNAQLAEKAA
                     RCDFVEQAHAEIASELAVLDGKYRHLQDENYALGNRFSAAEKQIAYLQEKEAESVRLK
                     QSYIELQEKAQGLAVENERLATQLGQERKAFADQYALERQIRQRIETDLEESRQTVRD
                     VQNDLSDVGNRFAAAEKQIAHLQEKEAEVERLRQSHTELQEKAQGLAVENERLATQIE
                     QERLASEEKLSLLGEARKSLSDQFQNLANTILEEKSRRFTEQNREQLHQVLNPLNERI
                     HGFGELVKQTYDKESRERLTLENELKRLQGLNAQLHSEAKALTNALTGTQNKVQGNWG
                     EMILETVLENSGLQKGREYVVQAASVRKEEDGGTRRLQPDVLVNLPDNKQIVIDSKVS
                     LTAYVRYTQAADADTAARELAAHVASIRAHMKGLSLKDYTDLEGVNTLDFVFMFIPVE
                     PAYLLALQNDAGLFQECFDKRIMLVGPSTLLATLRTVANIWRNEQQNQNALAIADEGG
                     KLYDKFVGFVQTLESVGKGIDQAQNSFQTAFKQLAEGRGNLVGRAEKLRLLGVKAGKQ
                     LQRDLVERANEQTAFALGKPSEQEAADEAE"
     gene            complement(7375..8007)
                     /locus_tag="ACFOV4_001679"
     CDS             complement(7375..8007)
                     /locus_tag="ACFOV4_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFC7619647.1"
                     /translation="MTLRYEIFPVTPFRQNCTLIWDDESGEAVLTDVGGDVPFLLQAL
                     ANRKLTLTAIWLTHGHLDHAGGVVEMLKTHKVPVLGSHREDEFLLQSLPQTTAQYGFP
                     VSPAFAPNRWLEEGETLKVGRYAFQVLHIPGHTPGHVVFYCAEAELLIAGDVLFYETI
                     GRTDFPRGNHADLINNIRNKLFALPETVQVVAGHGRMTSIGHEKRHNPFF"
     gene            8099..8923
                     /locus_tag="ACFOV4_001680"
     CDS             8099..8923
                     /locus_tag="ACFOV4_001680"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase"
                     /protein_id="HFC7619648.1"
                     /translation="MIKKTIGGIIPIFTAVFIPASAGAADLMLAQEYKGQDIAGWAMS
                     EKLDGVRAYWDGKHLISRQGYAFTPPKGFTAQFPPYPLDGELYSGRGQFEQISATVRS
                     VSSDWRGIRLHVFDVPKAQGNLYQRLAVATQWLKTHPNAPITIIPQTKVRDRQHAMDF
                     LKQIEAQGGEGVMLRQPESRYSGGRSSQLLKLKSQYDDECTVTRHYEGKGRNAGRLGA
                     IGCKNRHGEFRIGSGFKDKDRDNPPKIGTLITYRYRGFTRKGTPKFATFVRVRTDR"
     gene            8992..9555
                     /locus_tag="ACFOV4_001681"
     CDS             8992..9555
                     /locus_tag="ACFOV4_001681"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine-guanine phosphoribosyltransferase"
                     /protein_id="HFC7619649.1"
                     /translation="MTDLETKRLETQAMLENADLLFDQGQCRAALQKVADEITRDLGG
                     KYPLLLPVMGGAVVFTGQLLPLLRFPLDFDYVHVSRYGDKLEGGAFNWKRMPDAEQIR
                     GRHVVVLDDILDEGHTMSAIQAKLLEMGAASCRAAVFANKLIDKPKPIRADYVGLDVP
                     NRYVFGYGMDAAGCWRNLGEIYALDGK"
     gene            9636..10073
                     /locus_tag="ACFOV4_001682"
     CDS             9636..10073
                     /locus_tag="ACFOV4_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFC7619650.1"
                     /translation="MIGLLIITHETIGEAYRKLAHHFFPGGLPENVRILGVQPTEDQD
                     DIINNAIAALQEFPDNDGVLIMTDIFGATPCNAARRLVRENKSAILTGLNAPMMVKAV
                     QYSPAAEDLAAFTECVREAAVKGIFAITSAPEDLVCRRSGDAV"
     gene            10142..10411
                     /locus_tag="ACFOV4_001683"
     CDS             10142..10411
                     /locus_tag="ACFOV4_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HFC7619651.1"
                     /translation="MLKQSIEIINKLGLHARASSKFTQTASQFQSEVWVTKNGSRVNG
                     KSIMGLMMLAAAKGTVIELETDGADEAEAMRALTDLINGYFGEGE"
     gene            10411..12186
                     /gene="ptsP"
                     /locus_tag="ACFOV4_001684"
     CDS             10411..12186
                     /gene="ptsP"
                     /locus_tag="ACFOV4_001684"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFC7619652.1"
                     /translation="MSIVLHGVAAGKGIAVGCAHLIARGTEEVPQYDVAEADTDAEAE
                     RFDAAVKATRKELEQLRSAIPENAPTELGAFISLHLMLLTDVTLSREPVDILREQKIN
                     AEWALKQQSDKLAAQFDNMDDAYLRERKQDMLQVVRRIHNNLIGQGNELEVADNLFDE
                     TVLIANDLSPADTVLFKEQRIAAFVTDAGGPTGHTAILGRSLDIPSVVGLHNARKLIT
                     EGETVIVDGINGVLIIAPDESVLNEYRRRAREYRSHKRDLNKLKKTAAATADGVCIEL
                     VGNIESAEDVKPLHNLGADGIGLFRSEFLYLNRDTMPSEDEQYEVYSAIVKKMKGKSV
                     TIRTVDLGVDKNPRWFGKNSTPNGSLNPALGMTGIRLCLAEPVMFRTQMRAILRAAAH
                     GPVRMMWPMITSVSEVRQCLIHLDTAQRQLAERGDAFGKVGIGCMIEIPSAALTVGSI
                     LKLVDFISVGTNDLIQYILSVDRGDDSVSHLYQPGHPAVLKMLQHVIRTANRMDKDVS
                     VCGEMAGDTAFTRVLLGMGLRRFSMNPNNILPVKNIILHSNVGQLENEIAKIVRCEDE
                     EKAEKLIKQINSVSVEEEADFKGRK"
BASE COUNT         3060 a         3133 c         3505 g         2785 t
ORIGIN      
        1 ttatgtggtc gaacaaagct tcggtacgct gcaccgtaaa ttccgctatg cgcggtcaac
       61 ctatttcgga ctgattaaag tgagtgcgca aagccatctg aaggcgatgt gtttgaacct
      121 gttgaaagcc gccaacaggc taagtgcgcc cgctgccgcc taaaaagcag cccggatgcc
      181 tgattatcag gtatccgggc aggattaagg gggtatttgg gtagaattag gagatatttg
      241 gggcgaaaac agctgaaaac agctgaaaac ctgtgtttgg gtttcggctg tcgggaggga
      301 aaggaatttt gcaaaggtct cagattgggc aaaaatcaaa aacagtatag tggattaaca
      361 aaaatcagga caaggcgacg aagccgcaga cagtacaaat agtacggcaa ggcgaggcaa
      421 cgctgtactg gtttttgtta atccactata catgaaaaaa tagaaaaact gccgggtatg
      481 gttgaataag gggtcagacc ggttccaatt cgctcagtcc gggcaaatct gcaaaaccgc
      541 gttcgcgtat gatttggcaa aaattgttca gatagctctt gtccgtatct tcggtacgga
      601 tggcggcata cagtttgctt tgcaatccgt cggcagtaat ttggcggtgg acgacatagc
      661 ctttttcaag gtagggcatg actgtccaat agggaagggc ggcaatgcca cgtctgctgg
      721 caaccagttg gataatggcg atggtcagtt cgctgtgtcg gcgcggcggg ttgatgtttt
      781 tcggaatcag gatttttttg ggcaaatcca gcatctcgtc gggaacggga taagtaatca
      841 gggtttcccc gataaagtct tccgccgtcc aaacgttttt ggcggcaagc ggatggtctg
      901 gtgcgcaaat gccgaccatt tcgtaggcaa acagcggttg gaaagaaata tcgttttgtt
      961 tttccgcttc ggaaacaatg gcaaggtcgg cacggtgttg cagcagcagt ccgacgggat
     1021 ccgcttggaa tcccgatacg atatccaatt cgacttgggg ccacatcggg cggaattcgc
     1081 ccatggcggg catcagccag tcgaaacagg tatggcattc gacggcaatc cgcagctctc
     1141 ccgcctctcc ttccgtgatt cgcgccaaat cccattctgc aacagcaact tgaggtataa
     1201 gttcgtgggc gaggcgcagc agcctttcgc ccaccggggt aaagcgcaag ggcgtggatt
     1261 tgcgttcgaa cagcggcgtg ccgtagtggt tttcgagcat acggatctgg tgggaaaggg
     1321 cggattgggt aaggaaaacc cgtttggcgg caagggagac actgccggtt tcttcaagtg
     1381 ccagcagggt tttgaggtgg cgcaattcga taatggaatc catggggctt cagacggcat
     1441 attgaaccgg cgcatattaa aataattcat atgcgggtgc aaatcggaaa aatgtgaatt
     1501 ccggacattt tgcgattaga atgcccgctt gtttaaagcg attaggaaaa aagatggtat
     1561 tgcgcaggga ttttctgact tggtgtaatg aaacattgca gacagcgttg tttaaagatt
     1621 actcccctaa cggtttgcag gttgaaggga gggaatatat cgggaaaatc gttacgtcgg
     1681 taacggcaag cagggcagcg attgattttg ctgtggagca gaaggcagat ttgcttttgg
     1741 tacatcacgg tatgttctgg aaaaacgagt tgccgaccgt tactggttgg aaaaaagaac
     1801 ggattgccgc actgttacgg cacgacatca atatggcagg ctaccatctg cccctggatg
     1861 cacatcccac actgggcaac aatgcccaac tcgccgacag attgggtttt gcgacagaaa
     1921 aacggttcgg cgaacaaaac ctgctcaact cgggcagcct gaaacaagcc aagacactcg
     1981 gcgcattggc ggcgcatatt gaaacagttt tgcaacgtaa gcctgtcgtc atcggcaaac
     2041 ccgaacgcga aatccgacgg gttgcatggt gcagcggcgg ggcgcagggg ttttttcaga
     2101 cggcaataga cgaaggtgtc gatctgtatt tgacggggga aatctctgaa gcccaatacc
     2161 accttgccaa tgaaacgggt acggctttca tttcggcagg gcatcacgcg acggaacgtt
     2221 acggcgtacg cgcgctggca gaatcggcgg cagaggtttt cgggttggaa gtgtgccatt
     2281 ttgacgaaaa caatccggct tgagtcttga gaaatatcat aaaactttac cttattttaa
     2341 ataatgcttt gagtatcact gcaaactggg taaaattgca acgtttaatg gctcggtatt
     2401 cccaaaatat taggacgact gaataatgga taatcaagaa atcaacaacg gccgccgccg
     2461 tttcctgaca ctcgcgacct gcggcgcggg cggagtggca gcattgggtg tggcaacgcc
     2521 gtttgtggcc agttttttcc cttcggaaaa agccaaggcc gccggtgctg ccgtcgaggt
     2581 ggatgtcagt aaaatcgaag cgggtcagct gctgaccgcc gagtggcaag gcaaaccgat
     2641 ttgggtgctc aaccgtacag atcagcagct taaagacctg aaaggcctga acggcgaact
     2701 taccgatccc aattccgatg cggaacagca gccggagtat gctaaaaacg agacccgttc
     2761 gattaagccg aacatccttg tcgccatcgg tatctgcacc catttgggct gctcgcccac
     2821 cttccgtccc gacattgccc ccgccgattt gggtgcagac tggaaaggcg gcttcttctg
     2881 cccctgccac ggttcgaaat tcgacttggc cggccgcgta tataaaggtg ttcctgcccc
     2941 gaccaacctg gttgtcccgc catataaata cttgagcgac acaactatct tggtgggcga
     3001 agactaagaa taaggaacga taattatggc aaaccaaacc aatagcaaag caaaagcatt
     3061 gttaggctgg atggacgctc gtttccccct gtctaaaatg tggaatgagc atttggctca
     3121 atactacgca ccgaaaaact ttaatttttg gtactacttc ggctctttgg ccctgcttgt
     3181 cctcgtgatt caaatcgtca gcggcatttt cctgaccatg aactacaaac ccgacggcaa
     3241 cctgaacgcc taccatctgc ctgctgcctt tactgcagtc gagtacatca tgcgcgacgt
     3301 gtccggcggt tggattatcc gctacatgca ttccaccggc gcatctttct tcttcattgt
     3361 tgtttatctg cacatgttcc gtggtttgat ttacggttcg tacaaaaaac cccgtgagtt
     3421 ggtgtggatt tttggttctc tgattttctt ggcattgatg gcggaagcct ttatgggcta
     3481 cctgctgcct tggggtcaga tgtccttttg gggggcgcag gtaattatta acctgttctc
     3541 cgccatccct gttatcggtc cggatttgtc cacttggatt cgcggcgact tcaacgtttc
     3601 cgacgttacc ctgaaccgtt tctttgccct gcacgttatc gcggtacctc tggtattgct
     3661 cggcttggtt gtggcgcaca tcatcgccct gcacgaagtg ggttctaaca accctgacgg
     3721 cgttgaaatc aagaaaaaca aagacgaaaa cggtatcccg cgcgacggta tcccattcca
     3781 tccttactat accgttaaag acatcttggg tgtggttgta ttcctgattg tcttctgtgc
     3841 cgtattgttc ttcgcaccgg aaggcggcgg ctacttcctc gaagcgccga acttcgatgc
     3901 ggcaaatgcg ctgaaaacac ctccgcacat tgcgccggta tggtatttca caccgttcta
     3961 cgccattttg cgtgcgattc cctcgttctt gggaacgcag gtttggggtg taatcggtat
     4021 gggcgcggcg gtcgtgttga ttgccctgct gccttggctg gataggggcg aggtgaaatc
     4081 cgtccgttac cgcggcccga ttttcaaaac cgcattggtc ttgttcatca tttcctttat
     4141 cggtttgggt attttgggcg cgatggtggc aaccgatacg cgtactttgg tcgcgcgcat
     4201 cctgtccttc gtctatttcg cattcttcct gggtatgccg ttctatacca agctggataa
     4261 aaacaaaccg gttcccgaac gcgtaaccat gagcaccgcc aaacaaaaaa tcatgttctt
     4321 tgtttacgtc ggcattaccg ccgtgggtgc ttacctgttt gcaaccaaca tctgatgagg
     4381 gcagtcaaaa tgaaacaagc tatgaaaaat tggtttgctg ccttgctgtt ggcagtaccc
     4441 atgggtgcgg catttgcttc gggcggtcat gcacactatg agaaagtcga tatcgatttg
     4501 cgcgaccaag tcagcctgca gcgcggcgca caaatcttta ccaactattg cctgtcctgc
     4561 cactcggcaa gcggtatgcg tttcaaccgt ttgaaagaca tcggtttgac tgacgaagaa
     4621 atcaagaaaa acctgatgtt taccaccgat aatgtcggcg atgtcatgca ttcggcgatg
     4681 aacccgaaag atgcggcaaa atggtttggt gctgctccgc ccgatttgac attgattgcg
     4741 cgttccaaag gtgcagacta cctttacgcc tatatgcgcg gcttctataa agatccgacc
     4801 cgtccgagcg gctggaacaa taccgtattt gataaagtcg gtatgcctca cccgctgtgg
     4861 gaacagcaag gcgttcaagc cgttgagttg gatgccaaag gtcagccggt tatggtaaaa
     4921 gacgaacacg gcgagatgaa gcctaagctg tattgggaat ctaccggttt gcacagccgc
     4981 cgtctgccta acggcaaagt gatccaaaaa gagtacgacg catatgtacg cgatttggtc
     5041 aattaccttg tgtacatggg cgaacctgca caactgcaac gcaaacgtat aggctatgtc
     5101 gtgatgattt tcctatttgc ggttatgctg cctttggcgt atttcctgaa aaaagaatat
     5161 tggaaagacg tacactaagc gtttggaaca aaagggcaaa tcctttaggg tttgcccttt
     5221 tttcattttg cctgccgttt gaaaagcctg aatccgtatg ccgtctgaac atagctgcaa
     5281 catttcagac ggcatcattc taaaaatgtc agacatcggg aacttaatca gggtttgcgg
     5341 cggatggata ttgaattagg aaaaggcctg aaaccgcaag cagcatggta aggcgatgtc
     5401 gaacaggttt aaagccaatc cgctatattt tttggagcta tgtcgaacaa acaggtagaa
     5461 tcggaataag cggcggtttt gtccggtgtg aaaatgtttg aatattagga tgattgatgg
     5521 aactgatgac tgttttgctg cctttggcgg cgttggtgtc gggcgtgttg tttacatggt
     5581 tgctgatgaa gggcaggttt cagggcgagt ttgccgattt gaacgcgcaa ctggcggaaa
     5641 aggcggcaag atgtgatttt gtcgaacagg cacacgcaga aattgcatcg gaattggccg
     5701 ttttggacgg gaaataccga catttgcagg acgaaaatta tgctttgggc aaccgttttt
     5761 ccgcagccga aaagcagatt gcttatttgc aggaaaaaga ggcggaatcg gttcggctga
     5821 agcagtcgta tatcgagttg caggaaaagg cacagggttt ggcggttgaa aacgaacgtt
     5881 tggcaacgca gctcggacag gaacggaagg cgtttgccga ccaatatgcc ttggaacgcc
     5941 aaatccgcca aagaatcgaa accgatttgg aagaaagccg ccaaactgtc cgcgacgtgc
     6001 aaaacgacct ttccgatgtc ggcaaccgtt ttgccgcagc cgaaaaacag attgcccatt
     6061 tgcaggaaaa agaggcagag gtggagcggt tgaggcagtc gcataccgag ttgcaggaaa
     6121 aggcacaggg tttggcggtt gaaaacgaac gtttggcaac gcaaatcgaa caggaacgcc
     6181 ttgcttctga agagaagctg tccttgctgg gcgaggcgcg caagagtttg agcgatcagt
     6241 ttcaaaatct tgccaacacg attttggaag aaaaaagccg ccgttttacc gagcagaacc
     6301 gcgagcagct ccatcaggtt ttgaacccgc taaacgaacg catccacggt ttcggcgagt
     6361 tggtcaagca aacctatgat aaagaatcgc gcgagcggct gacgttggaa aacgaattga
     6421 aacggcttca aggattgaat gcgcagctgc acagcgaggc aaaggcactg accaacgcgc
     6481 tgaccggtac gcagaacaag gttcagggca attggggcga aatgattctg gaaacggttt
     6541 tggaaaattc cggcctccag aaagggcgcg aatatgtggt tcaggcggca tccgtccgaa
     6601 aagaggaaga cggcggcacg cgccgcctcc agcccgacgt tttggtcaac ctgcccgaca
     6661 acaagcagat tgtgattgat tccaaggtct cgctgacagc ttatgtgcgc tacacgcagg
     6721 cggcggatgc ggatacggcg gcacgcgaac tggcggcaca cgttgccagc atccgtgcac
     6781 acatgaaagg cttgtcgctg aaggattaca ccgatttgga aggtgtgaac acattggatt
     6841 tcgtctttat gtttatccct gtcgaaccgg cctacctgtt ggcgttgcag aatgacgctg
     6901 gcttgttcca agagtgtttc gacaaacgga ttatgctggt cggccccagt acgctgctgg
     6961 cgactttgcg gacggtggcg aatatttggc gcaacgagca gcaaaaccaa aacgcgctgg
     7021 cgattgcgga cgaaggcggc aagctgtacg acaaatttgt cggctttgta cagacgctcg
     7081 aaagcgtcgg caaaggcatc gatcaggcgc aaaacagctt tcagacggca ttcaagcaac
     7141 ttgccgaggg gcgcgggaat ctggtcggcc gcgccgagaa actgcgtctg ttgggcgtga
     7201 aggcaggcaa acagcttcaa cgggatttgg tcgagcgtgc caacgaacag acggcatttg
     7261 ctttgggcaa accttcggaa caggaagcgg ctgacgaagc cgaataggaa aggcggatgc
     7321 gtttcagacg gcatcagtgc agatgacgcc gtctgaagac cgtagtgaag tcggttagaa
     7381 aaacggattg tgccgttttt cgtgtccgat ggaagtcata cgcccgtgtc cggcgacaac
     7441 ttgcacggtt tcggggaggg cgaataattt gttgcggata ttattgatta agtcggcgtg
     7501 gttgccgcgc ggaaaatcgg ttctgcctat ggtttcgtaa aacagcacgt cgcccgcaat
     7561 cagcagctcc gcttcggcac aatagaaaac cacgtgtccc ggcgtgtgcc ccggaatatg
     7621 cagcacttga aaggcatagc gtccgacttt gagcgtttcg ccttcttcga gccaacggtt
     7681 cggcgcaaag gcgggcgaga cgggaaatcc gtattgcgcg gtggtttgcg gcagcgattg
     7741 gagcaggaat tcatcttcgc ggtgcgaacc gaggacaggg actttatgcg ttttcaacat
     7801 ttcgaccacg ccgcccgcgt gatcgagatg gccgtgcgtc agccagattg ccgtgagcgt
     7861 aagtttgcgg tttgccaacg cttgcagcag gaacggcacg tcgccgccga catcggtcag
     7921 gacggcttcg ccgctttcgt cgtcccaaat cagggtgcag ttttggcgga agggggtaac
     7981 ggggaagatt tcgtaacgta gggtcatcgg cgtgttccta aacggttttt cagacggcat
     8041 cgggtttgcc gtttgtttta tggcggtttg ccgcctgttt tgatatttgg ggaatcagat
     8101 gattaagaag acaatcggcg gcatcatacc gatttttacg gcggttttca tccctgcatc
     8161 ggcaggcgcg gcggatttga tgctggcgca ggaatacaaa gggcaggata ttgccggctg
     8221 ggcaatgagc gagaaactcg acggcgtgcg cgcctattgg gacggaaagc acctgataag
     8281 ccgtcagggc tacgcgttta cgccccccaa aggctttacc gcgcagtttc cgccttatcc
     8341 tttggacggc gaattgtata gcggacgtgg tcagttcgag cagatttccg ctaccgtgcg
     8401 ttctgtttct tcagactggc gcggcatccg cctgcacgtt ttcgatgtac ccaaggcgca
     8461 gggcaatctc taccaacgtt tggcagtcgc aacgcagtgg ctgaaaacgc atccgaacgc
     8521 gccgattacc atcatcccgc aaaccaaagt gcgcgaccgg cagcacgcga tggacttttt
     8581 aaaacaaatc gaagcgcagg gcggcgaagg cgtgatgctg cgtcagcccg aatcccgtta
     8641 cagcggcggc aggagcagcc aattattgaa gctgaaaagc caatacgacg acgaatgcac
     8701 ggtaacgcgg cactatgagg gcaaagggcg aaacgccgga cggttgggcg cgatcggctg
     8761 caaaaaccgg cacggcgaat tccgcatcgg cagcggtttc aaagacaaag accgcgacaa
     8821 cccgcccaaa atcggcacac tgattaccta ccgctaccgt ggttttacgc ggaaaggcac
     8881 gccgaaattt gccacatttg tgcgcgtgcg taccgaccgc tgagcaggac ggttcagacg
     8941 gcatccgata ctttggttta taattttcct tttaccgacc gattccgaca tatgaccgat
     9001 ttagaaacca aacgccttga aacacaggcg atgcttgaaa acgccgatct tttgttcgac
     9061 caaggccaat gccgtgccgc actgcaaaaa gtggcggacg agattacgcg cgatttgggc
     9121 ggcaaatatc cgctgctgct gcccgtgatg ggcggcgcgg tggtgtttac ggggcagttg
     9181 ctgccgctgt tgcgttttcc cttagatttt gattatgttc acgtttcccg ttacggcgac
     9241 aagctggagg gcggcgcgtt caactggaag cgtatgcccg atgcggaaca aatccggggc
     9301 aggcacgtcg tcgtgctgga cgatattttg gacgaagggc atacgatgtc cgccattcaa
     9361 gccaaacttt tggaaatggg tgcggcaagc tgccgtgcgg cggtgttcgc caacaagctg
     9421 attgacaaac ccaagcctat ccgagccgat tatgtcggac tggatgtgcc gaaccgttat
     9481 gttttcggtt acggcatgga tgcggcgggc tgctggcgca atttgggcga gatttacgca
     9541 ttggacggaa aataaggacg cgatgccgtc tgaaggctgt tcagacggca ttgcgcccat
     9601 acgccggcag gacaacgagg aacaggacgc ataatatgat agggctttta atcatcacac
     9661 acgaaaccat aggcgaagcc taccgcaagc tggcacatca tttttttccg ggcggactgc
     9721 ctgaaaacgt ccgcatactc ggcgtgcaac cgacggaaga ccaagacgac atcatcaaca
     9781 acgccattgc cgcgcttcag gaatttcccg acaacgacgg cgtgctgatt atgaccgata
     9841 ttttcggcgc gaccccctgc aatgcagccc gccgcctcgt gcgcgaaaac aaatcggcga
     9901 ttttgaccgg actgaacgcg ccgatgatgg ttaaggccgt ccaatattcg ccggcggcgg
     9961 aagaccttgc cgcctttacc gaatgcgtca gggaggcggc ggtaaaaggc attttcgcca
    10021 tcacgtccgc gcccgaagat ttggtgtgcc ggcgcagcgg cgatgccgtc tgaagaagcg
    10081 gcagggcagg aaaacatttt aaacggcgtc tgctgccgat atacataaca cgggaatcga
    10141 aatgctcaaa caatccatcg aaatcatcaa caaactcgga cttcacgccc gtgcctccag
    10201 caaattcacc caaaccgcgt ctcagtttca aagcgaagtc tgggtaacga aaaacggcag
    10261 ccgcgtcaac ggcaaaagca tcatggggct gatgatgctc gccgccgcca agggtacggt
    10321 catcgagctg gagacggacg gcgcggacga ggcggaagcg atgcgcgccc tgaccgactt
    10381 aatcaacggc tacttcggcg agggcgaata atgagtatcg tgctgcacgg cgtggcggcg
    10441 ggcaaaggca ttgccgtcgg ttgcgcccac ctgattgcgc gcggtacgga ggaagtgccg
    10501 cagtatgatg ttgcggaggc ggacaccgat gccgaagccg aacgtttcga tgccgccgtc
    10561 aaagccacgc gcaaagagtt ggaacagctc cgcagcgcga ttcccgaaaa cgccccgacc
    10621 gagttgggcg cgttcatctc gctgcacctg atgctcttga ccgatgttac cttgtcgcgc
    10681 gaacccgtcg atattttaag ggaacaaaaa atcaacgccg agtgggcatt gaagcagcag
    10741 agcgacaaac tcgccgccca attcgacaat atggacgatg cctatttgcg cgaacgcaag
    10801 caggatatgc tgcaagtcgt ccgccgcatc cacaacaacc tgatcgggca gggcaacgag
    10861 ttggaagttg ccgacaacct gtttgacgaa accgttctga ttgcaaacga cctttcgccc
    10921 gccgacacgg ttttgtttaa agagcagcgc attgccgcct tcgttaccga tgccggcggc
    10981 cccaccgggc atacggcgat tttgggcagg agcttggaca tcccgtccgt cgtcgggctg
    11041 cacaacgcgc gcaaactgat taccgagggc gaaacggtca ttgtggacgg tatcaacggc
    11101 gtgttgatta tcgcgccgga tgagtcggtg ttgaacgaat accgccgccg tgcccgcgaa
    11161 taccgcagcc acaaacgcga tttgaacaag ctcaaaaaaa ccgccgccgc caccgctgac
    11221 ggggtctgca tcgagcttgt gggcaatata gaatccgccg aagacgtgaa accgctgcac
    11281 aacctcggcg cagacggcat cgggctgttc cgcagcgagt ttctttacct gaaccgcgat
    11341 acgatgccgt ctgaagacga gcagtacgaa gtgtacagcg cgattgtcaa aaaaatgaaa
    11401 ggcaaaagcg taacgatacg gacagtcgat ttgggtgtgg acaaaaaccc gcgctggttc
    11461 gggaaaaaca gcacgcccaa cggcagcctc aaccccgcgc tgggcatgac cggcatccgc
    11521 ctgtgccttg ccgaaccggt catgttccgc acccagatgc gcgccatcct ccgcgccgcc
    11581 gcccacggcc ccgtgcggat gatgtggccg atgattacct ccgtatccga agtgcgccag
    11641 tgcctcatcc acctcgacac cgcgcaacgc cagcttgccg aacgcggcga tgccttcggt
    11701 aaagtcggca tcggctgtat gattgaaatt ccgtctgccg cgctgaccgt cggcagtatt
    11761 ttgaaactgg tcgatttcat ctccgtcggt accaacgacc tgattcaata catcttgtcc
    11821 gtcgatcgcg gcgacgacag cgtcagccac ctctaccagc ccggccatcc cgccgtgctg
    11881 aaaatgctgc aacacgtcat ccgtaccgcc aaccgcatgg acaaagacgt atccgtatgc
    11941 ggcgagatgg cgggcgatac cgcgtttacc cgcgttttat tgggtatggg gctgcgccgt
    12001 ttttccatga accccaacaa catcctgccc gtcaaaaaca tcattctgca cagcaatgtc
    12061 ggacagctcg aaaacgagat tgccaaaatc gtccgttgcg aggacgagga aaaggcggaa
    12121 aagctgatca aacagatcaa cagcgtgtct gtcgaggaag aagccgactt caaggggcgg
    12181 aaataaatac ggcaggtaaa aaatagaaat acttaacaat gcccgcaatc tgaaattttg
    12241 ccattcttgc aaaatagaaa accgaaacag aaacccaaaa tcggccattc cctcaaaaac
    12301 agaaaaccaa aatcagaaac ctaaaatccg tcattcccgc gcaggcggga atctaggtct
    12361 gtcggcacgg aaacttatcg ggtaaaacgg tttctttaga ttttacgttc tggattcccg
    12421 cctgcgcggg aatgacgatg aaaagattgt tgtcgcttcg gataaatttt tgccgtgttg
    12481 ggt
//
LOCUS       DAXISH010000059        12418 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.059, whole genome shotgun sequence.
ACCESSION   DAXISH010000059 DAXISH010000000
VERSION     DAXISH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12418
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.059"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(71..487)
                     /locus_tag="ACFOV4_001685"
     CDS             complement(71..487)
                     /locus_tag="ACFOV4_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619653.1"
                     /translation="MSGEKSENLPADEQQKMLQEFLELQKQDIAVKQKELESRKDEIQ
                     SHERIALATIEAQKQGEQQHGEIFKEVHKRRLNAVIAISFLIAAVLITALWRDKDSVA
                     IEIVKIGGAVALGYFAGINRGKAQTLEKQRREKDSD"
     gene            complement(484..675)
                     /locus_tag="ACFOV4_001686"
     CDS             complement(484..675)
                     /locus_tag="ACFOV4_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619654.1"
                     /translation="MNTVKEYTAVRERLLNAADYLEEVRKDRKTGNIASVEFVPPKIG
                     ARGYGKFKVRYKTLVAVDL"
     gene            1198..1365
                     /locus_tag="ACFOV4_001687"
     CDS             1198..1365
                     /locus_tag="ACFOV4_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619655.1"
                     /translation="MVDEKLAENRKRYEQKRVIKKVSFNAETEKELLEYAQNIDFSQW
                     VKSIIKEKIKK"
     gene            1638..1823
                     /locus_tag="ACFOV4_001688"
     CDS             1638..1823
                     /locus_tag="ACFOV4_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619656.1"
                     /translation="MPDEKTLKAKQAEYQRKYDQKRLMKTVSFHLEREKELVDFMQKE
                     IPDFSNWVKSVMKEKMK"
     gene            2024..2224
                     /locus_tag="ACFOV4_001689"
     CDS             2024..2224
                     /locus_tag="ACFOV4_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619657.1"
                     /translation="MDSIKKAQEKYALKRVVKTVSFNSEKELDLIKFSENLDFSNWVK
                     SKIRGDMESEKFKKKAKKNIDK"
     gene            2374..2964
                     /locus_tag="ACFOV4_001690"
     CDS             2374..2964
                     /locus_tag="ACFOV4_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HFC7619658.1"
                     /translation="MNTQLIPTVSGQLDNQTQALVDAHDLHKFLGVETPFSKWIQRRI
                     EEYGFTQALDFIGVDKIVRTEAGFFGQRDKTVQGYYLSLDMAKELCMVERNDKGRQAR
                     RYFIEMEKQAKALPDAVLYRIDALEDAYFQAAPEMLALLRYRSMGLNLTEIGKLLDMN
                     PGAVSYRLKKLNDLGFLEYVPKPKMVVQQQSLGLEG"
     gene            2968..3183
                     /locus_tag="ACFOV4_001691"
     CDS             2968..3183
                     /locus_tag="ACFOV4_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619659.1"
                     /translation="MNTTYTLTFDQDSLKALNLLVFTLNHLKVLEMDMEGIEDGLSAV
                     IETASEKADKLSAAFYNAVYEQEEKAA"
     gene            complement(3344..3862)
                     /locus_tag="ACFOV4_001692"
     CDS             complement(3344..3862)
                     /locus_tag="ACFOV4_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0042262 - DNA protection [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="HFC7619660.1"
                     /translation="MAKTRIKQPAIEAAQDKTEVTAFIRQIGDLQREVKRLETEAGDK
                     KAAIEEEYAAQAAPMCAEIMSLTERVAAYCEAHKDELTENGKTKTVDFTTGLIKWRIR
                     PPSVKVTGVAAVLAWLSEKSAFAEFVRTKKEIDKDAILNQKERFSDGQVPGIKIVSGV
                     EDFVIEPSEQIL"
     gene            complement(3972..4139)
                     /locus_tag="ACFOV4_001693"
     CDS             complement(3972..4139)
                     /locus_tag="ACFOV4_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619661.1"
                     /translation="MNEKDLIEWLEDRGELMVMKKDGEGFVIAARAPDGMWKTAEAET
                     LAQAITLWEEV"
     gene            complement(4132..4305)
                     /locus_tag="ACFOV4_001694"
     CDS             complement(4132..4305)
                     /locus_tag="ACFOV4_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619662.1"
                     /translation="MSFGRRNTDWQAWGQHRRRATKFMVKRNREQEVAEYQAQFEDKD
                     GKGRLKTEGNKDE"
     gene            complement(4414..4680)
                     /locus_tag="ACFOV4_001695"
     CDS             complement(4414..4680)
                     /locus_tag="ACFOV4_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619663.1"
                     /translation="MQVLKKVDWKMFVARSFWRWVPVGLTVGVWCFVAGMALHSCAKE
                     PEPVAKEPTKVEAMERQADLEVKVWEGQYESMSVEEKMKGIVYE"
     gene            complement(4770..5684)
                     /locus_tag="ACFOV4_001696"
     CDS             complement(4770..5684)
                     /locus_tag="ACFOV4_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFC7619664.1"
                     /translation="MKQINQALQQKLVEFKEKSGMNQTQLARGIDTSPASISMYLNGT
                     YADKGGNYETIETKIEAFLEMEDSKARREELVLGFVSTKTTRRIAEVMRDAHEGGETV
                     VIYGQAGLGKTQSVKNYCEKNPAAILIEANPSFTALVLMRKLATAAKVSAMGSLNDLF
                     ESVSDRLRDSGRLIVVDEAENLPLRALEIIRRLHDETGCGLVLSGMPRLVANLRGKHG
                     ELVQLYSRVSVALNLGESLPDDELFEIAKAALPDADEETLLELVKHSNGNTRRMSKLM
                     RGAVRTANKNGIKMQAGIVKKYSSLIIR"
     gene            complement(5720..7696)
                     /locus_tag="ACFOV4_001697"
     CDS             complement(5720..7696)
                     /locus_tag="ACFOV4_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="HFC7619665.1"
                     /translation="MKYMDLKSLLNFGLPNMPRTVIGLRKKAQRDGWQTRRRQGKGGG
                     VEYALPAEIRAAIMKRQSDELAEKMPKMLPQVRPGTAMSAQALAEAAKLLNEKQRSVA
                     NARCAVVAAVLGIKYQYGCSAKAAVAQFLGLLAESKLDAVTLGNLEKANDRSRTAKVG
                     ERTLDGWISAYLKAENATERLVALAPKTTKAVKPIESYGWLPMFMQFHNIPSAPKLAH
                     SYRRFVQWAEAENMPVNDVPNLSMVRRVWDKLPLIMQERGRKTGAAYKSLLPYVKRDW
                     GALKPNDVWIGDGHSFKAKVAHPVHGRPFKPEVTVIIDGCTRFVVGFSVSLAESCVAV
                     SDALRIGVKHFGLPIIYYSDNGGGQTGKTIDHEITGITSRLGIRHETGIVGNPQGRGI
                     IERWWKDNLIEMARQYETFAGAGMDSSTKNLMYRKMESAFNALEKGKDLTEEQQKYLK
                     KLPSWSRFIADVVKCIDEYNNRPHGELPRHPDGGHYTPKAYREMRLEQDGIAPDMLSA
                     QELATMFMPQEVRKVQRGWLDLFNNSYFSTELAEYHKDEVRVSYDLSDASVVNVFDMD
                     GKFITKAQADGNTREAFPTARIDQLAENRRKGKIKRAENAIKLANAEVNPALEQAAAW
                     DELGHLGGNVIEAEYAVLPKTGTDDFVLFETDRS"
     gene            complement(7698..8027)
                     /locus_tag="ACFOV4_001698"
     CDS             complement(7698..8027)
                     /locus_tag="ACFOV4_001698"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC7619666.1"
                     /translation="MYIIQVTVKAGIKACKVSNGFYHGGIMQANEIYKSLEEKNISAR
                     MLASALGVTNQSVSEVIRNGRGSKRIAEAIAKVIQKDLVEVFPHYKKTDCRDKKIAEL
                     KEMLGVG"
     gene            7993..8892
                     /locus_tag="ACFOV4_001699"
     CDS             7993..8892
                     /locus_tag="ACFOV4_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFC7619667.1"
                     /translation="MPALTVTWMIYTKYLVYQIYLAIFCDVFMERIDLALNLVEERSR
                     LGYSRKNFAEQTGCSAESLRLYESGQVNIPADFLLAAVQLGVDIQFVFTGIHSANLNA
                     VSDDLNKKLDDAIGKSNVENQINGNVSNAVIASSGSVVHQINTQNHVIRTRVDSKPGK
                     EHITLEQASKLQQLVKQVAAAEEIAKRSPKSIRAIWASLNAHCKVPSYKLIALSDYDK
                     AETYLRKWLGRLSNTATSKNNDPDWRKKKYAYIKLNVKQLELEDWLKSYLEKNFSVES
                     LTELSDEDLQKTYAAVSTKKRKK"
     gene            9101..9316
                     /locus_tag="ACFOV4_001700"
     CDS             9101..9316
                     /locus_tag="ACFOV4_001700"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC7619668.1"
                     /translation="MRIGNDLFVKRVQRIPGKLLVTSENPRYAPFEIDLSNTQDDIAI
                     IGRVEWYGRSIPHRKTSLCSATTAKSC"
     gene            9274..9864
                     /locus_tag="ACFOV4_001701"
                     /pseudo
     CDS             9274..9864
                     /locus_tag="ACFOV4_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707572.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            9968..10636
                     /gene="hda"
                     /locus_tag="ACFOV4_001702"
     CDS             9968..10636
                     /gene="hda"
                     /locus_tag="ACFOV4_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA regulatory inactivator Hda"
                     /protein_id="HFC7619669.1"
                     /translation="MNQLIFDFAAHDYPSFDKFLGTENAELVYVLQHKHGQFIYVWGE
                     EGAGKSHLLQAWVAQALEAGKNAAYIDAASMPLTDAAFEAEYLAVDQVEKLGNEEQAL
                     LFSIFNRFRNSGKGFLLLGSEYTPQQLVIREDLRTRMAYCLVYEVKPLTDQEKIDALA
                     SMAAARQVTVDSEIFEYLLKHWRRDMDSLMMMLDTLDNYAVTMGKRITLPLLRQLLKQ
                     QETQ"
     gene            10633..11301
                     /locus_tag="ACFOV4_001703"
     CDS             10633..11301
                     /locus_tag="ACFOV4_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFC7619670.1"
                     /translation="MKNLAIFDLDNTLINTDSDHAWPQYLIKKGLVDAAETEAQNEKF
                     YRDYQNGCLDIDAFLKFHLAPLARYSKEELAEFHREFMAKYIIPHISPMQRMLVQSHQ
                     MAGDETLVISSTNEFIITPVCHLFGITNIIGTQLETGSDGRYTGNYIGTPSLKEGKIT
                     RLNQWLAERGETLQSYGKTYFYSDSRNDLPLLRLVSEPVAANPDAELEKEAKEKGWPV
                     LNFK"
BASE COUNT         3350 a         3274 c         2513 g         3281 t
ORIGIN      
        1 aaaaatgccg tctgaaaacg agctttgcga gtttcgccaa aacgtttcag acgacctttt
       61 ttactacaat ctaatcactg tctttttcgc gccgttgctt ttccaaggtt tgcgctttac
      121 ctctgttgat tcctgcaaaa tatcccaaag ctaccgcccc gccgattttg acaatttcaa
      181 tagcgacgct gtccttatcg cgccataacg cagtaatcag cacggcggca atcagaaaag
      241 aaatagcaat cacggcattc agacggcgtt tgtgtacctc tttgaaaatc tcaccatgtt
      301 gctgttcacc ctgtttttgc gcttcgatgg tagccagtgc aatgcgttcg tgagattgga
      361 tttcgtcctt acggctttcc aactccttct gtttgactgc aatatcctgt ttttgaagtt
      421 ctaaaaactc ctgaagcatt ttctgctgct catcggccgg cagattctcg gatttttccc
      481 cgctcataaa tcaaccgcca ctaaggtttt gtaacggact ttgaatttgc cgtaaccccg
      541 agcccctatt ttcggcggca caaattccac ggacgcaata ttgcccgtct tacggtcttt
      601 acggacttct tccaaataat cggcagcatt gagcagccgt tcgcggactg ccgtatattc
      661 tttgacggta ttcatttttc aacctcgccc aaatagtgca aatattagca tatgggattt
      721 atttttcaag aaaatcaaat ccatataaaa caaccgtata atattttaat actatatatg
      781 gtaaatttct tctaaaaata cacactaaaa taccatatct tgataaccgc aacgccgcac
      841 aaatggcagg gcattgatgc ccgacaacaa aaaatgccgt ctgaaacagc attcgagctg
      901 ttttcagacg gcatttttct ttgattttgt tggggaaagg gttgactttt aacgtgtcca
      961 cgtttataat tcaattcatc ggcgtagtga gggccgatac gggaaaagcc ccaccgaagc
     1021 ggggctcaac tgggagaaag aagatgaata aacgcactat tcaaattctc atcttggtcg
     1081 cagttttcat gttggcaagt gctaatgcct actaaagact gaccagctgg gggcggtcgc
     1141 cgctgtcccc agtcccaatc ttacaaaata cggtttaaaa aatcaaggag tttgcctatg
     1201 gttgatgaaa aactggcaga aaaccgaaag cgttacgagc agaaacgggt gattaagaaa
     1261 gtctcgttca atgccgaaac ggaaaaagaa cttttggaat atgcccaaaa tatcgatttt
     1321 tcccaatggg ttaaatcaat catcaaagaa aaaatcaaaa aatagcttga ctaaattcta
     1381 gaaatactag ataatacgcc tatctgataa agcaaagccc cgaagcggca acttcggggg
     1441 cttatcggat agaaaggagg cttgtggaaa tgacaaaact ggcgaaagtt gtttttttca
     1501 tcattctgct tttaagctgt agtccggctt actaagcaag ttgattaaac acaaggggtg
     1561 gcagaacacc gcgccccttt cgccaacctt tctgcaagcc attttactac aacgatttta
     1621 aaaatcaagg attgcctatg cctgatgaaa aaacgctaaa agcaaaacaa gctgaatatc
     1681 agcgaaagta tgaccaaaag cggctgatga aaacagtttc tttccatttg gaaagagaga
     1741 aagagttggt ggattttatg caaaaagaaa ttcccgactt ttcaaactgg gttaaatcag
     1801 tcatgaagga aaaaatgaaa taagaaaatt ccgccgatgg gaaaacatcg gcggaacagg
     1861 tggaaagcag agcagcaact ctctttatgt agggcatgaa aaaaggccgt ctgaaacagg
     1921 ttttaaaccc catttcagac ggctttttgt tgtaatacat cttgattaaa atggttttta
     1981 gtattaccat aatcgtgttt taaaacctat ttaaaggaag attatggact cgattaaaaa
     2041 ggctcaagaa aaatacgcac tcaagcgagt agtgaaaaca gtatcgttca attccgaaaa
     2101 agaacttgat ttaattaaat tttctgaaaa tttagatttt tcaaactggg taaaatcgaa
     2161 aattagagga gatatggaat cggaaaaatt caaaaaaaaa gcaaaaaaga atattgacaa
     2221 atagaattac cataatttaa aatttccata tcttgtgcaa cacaagatat ggaaatcccc
     2281 gataagtgac agcttatcgg ggatagtgga aaagcaacgt tagagcgttc ttttccttgt
     2341 catctcaacc ttgaaatgaa agataatttt accatgaata cccaactcat cccaactgtt
     2401 tcaggtcaat tggacaatca aacacaagca ctggttgatg ctcatgacct gcataagttc
     2461 ttaggtgtgg aaacaccatt ttctaaatgg attcagcgtc gcattgaaga atacggattt
     2521 acacaagccc ttgattttat cggcgtggac aaaattgtcc gcaccgaagc aggtttcttt
     2581 ggacagcgtg ataaaactgt tcaggggtat tatttatccc tcgacatggc aaaagagctg
     2641 tgcatggtgg agcgcaacga caaaggacgc caagcccgcc gatattttat cgaaatggag
     2701 aaacaggcaa aagccctgcc tgatgccgtg ctataccgca tcgatgcatt ggaagacgcc
     2761 tatttccaag ccgcgcccga aatgctcgcg ctgctgcgct accgcagtat gggcttgaac
     2821 ctgaccgaaa taggcaaact cttggacatg aaccccggcg cggtttccta ccgtctcaaa
     2881 aaactcaacg atttgggttt cttggaatat gtccccaagc ccaaaatggt ggtgcaacaa
     2941 cagtctttgg gattggaggg ttaagccatg aataccacct ataccctgac tttcgaccaa
     3001 gacagcctca aagccctgaa tctgctggtg ttcacactca accatctgaa agttttggag
     3061 atggacatgg aaggaatcga agacggtttg tctgccgtga ttgaaaccgc ctccgagaaa
     3121 gccgacaagc tgtccgccgc tttctacaac gccgtgtacg agcaggaaga gaaagcagcc
     3181 tgaatctagg gcatgaaaaa aggccgtctg aaacaggttt taaaccccgt ttcagacgac
     3241 ctttaaatca tgggttaaag cctatttgaa ccggctaggc aagctcctgc tccgtaggct
     3301 caatcacgtt tcaacacact gaattgaaat caggctgttg attttataga atttgttcgc
     3361 tcggctcaat cacaaaatcc tccacgccgc tcacaatctt aatccccggc acttggccgt
     3421 ctgaaaaacg ctctttttga ttcaggatgg cgtctttgtc gatttccttt ttagtgcgga
     3481 caaactcggc aaaggcggat ttttccgaga gccacgccaa gacggcggcc acgcccgtta
     3541 ccttgacgga tggcggacgg atgcgccatt taatcaggcc ggtagtaaag tccacggttt
     3601 tggttttacc gttttccgtc agctcgtcct tatgtgcctc gcagtatgcg gccacacgtt
     3661 cggtcaggct catgatttcg gcacacatcg gcgcggcttg ggcggcatat tcttcttcga
     3721 tggccgcttt tttgtctccg gcttcggttt ccaggcgttt gacttcgcgc tgcaagtcgc
     3781 cgatttggcg gataaatgca gtaacttccg ttttgtcttg tgccgcttcg atggcgggct
     3841 gtttgattcg ggttttagcc attttctctt cctttcaggt tgggtttaac atttcggctt
     3901 actcaagcct tgttcgcgtt cgtgcttggc aagtgcttca actttcgcgc ggtttctcaa
     3961 aaacttaaac atcacacttc ctcccataaa gttatcgcct gagccaaagt ttccgcctcg
     4021 gcagtcttcc acatcccgtc cggcgcacgc gctgcaatca caaagccttc gccgtccttc
     4081 ttcatgacca tcagctcgcc acggtcttcg agccattcga ttaaatcttt ttcattcatc
     4141 tttgtttcct tccgttttca gacgaccttt gccgtcctta tcttcaaact gcgcctgata
     4201 ttcggcgact tcctgctcgc ggtttcgctt caccataaac ttcgtcgcac gcctgcggtg
     4261 ttgtccccaa gcctgccaat ccgtattacg tcgtccgaaa ctcatttcac acatcctttc
     4321 acaatcgcct tatcgccata tttcgcgcgg atttccttta ccgcccgtgc caaagcctct
     4381 tttttcgccg cagggctcaa taaaattggc ttatcactca taaacaatcc ctttcatttt
     4441 ttcctcgacg ctcattgact cgtattgccc ttcccatacc ttgacctcca aatccgcctg
     4501 tctttccatc gcctcaacct tcgtcggctc tttcgcaacc ggttcgggtt ctttcgcgca
     4561 ggaatgcaac gccattcccg ccacaaaaca ccacacgccc accgtcaaac caaccggcac
     4621 ccaacgccaa aaagagcgcg ccacaaacat cttccaatca actttcttca aaacttgcat
     4681 tttgcgtttt ccttttaaaa caacaactta ttaaaatcat agggtaaaaa aatatatagc
     4741 cctgtcagag acttaccgtt tcagacggcc tatcggataa tcagggagct gtatttctta
     4801 acgataccgg cctgcatctt gataccgttc ttgttcgccg tgcgtaccgc gccgcgcatc
     4861 aatttactca tccggcgcgt attgccgtta ctatgtttaa ccagttccaa gagcgtttct
     4921 tcgtccgcat caggcaaagc cgctttcgca atctcaaaga gttcgtcatc cggcaaagat
     4981 tcgcccaaat tcagcgcaac agacacgcgg ctataaagtt gcaccagctc gccatgctta
     5041 ccgcgcaaat tcgcaaccag tcggggcata ccgctcaaca ccaaaccgca gcccgtttca
     5101 tcatgcagtc ggcggataat ctcaagggcg cgcaagggca ggttttccgc ttcatcgacc
     5161 acaatcagac ggcccgaatc gcgcaggcgg tcagatacag actcaaacaa atcattcagg
     5221 ctgcccatcg ccgatacctt cgccgccgtc gccaacttgc gcatcaggac caaagccgta
     5281 aagctcggat tagcctcaat caagatagcc gcagggtttt tctcgcagta gtttttgacc
     5341 gactgcgtct tgcccaaacc cgcctgaccg tagatcacca ccgtttcgcc gccttcgtgc
     5401 gcatcgcgca tcacttccgc gattcggcgt gtcgtcttag tcgatacaaa tcccaacacc
     5461 agctcttcac gtcgcgcctt actgtcctcc atctccaaaa acgcctcgat tttcgtctcg
     5521 atggtttcat aattgccgcc tttatcggca taagtgccgt tcagatacat actgatggag
     5581 gccggcgaag tatcgatacc gcgtgccagt tgggtttggt tcattcccga tttttcttta
     5641 aattcaacca gtttttgttg caatgcttga ttaatttgtt tcattttttt agtcctttta
     5701 aaagaggttt aaaaccgttt taacttctat ccgtctcaaa tagcacaaaa tcgtccgtgc
     5761 ccgttttcgg caataccgca tactccgcct cgatgacgtt tccgcccaaa tgtcccagct
     5821 cgtcccaagc tgccgcctgt tccagtgccg gattgacttc cgcatttgcg agcttgattg
     5881 cattttccgc ccgcttgatt ttgccttttc ggcggttttc cgccagttgg tcgatacgcg
     5941 ccgtcgggaa agcctcgcgg gtattgccgt cggcctgcgc cttagtgata aacttgccgt
     6001 ccatatcaaa cacattgacc accgacgcat cgctcaaatc gtagctgacc cgtacctcgt
     6061 ccttgtgata ctccgccagc tcggttgaga aataagagtt gttgaacaaa tccagccaac
     6121 cgcgctgtac ctttcgcacc tcttgcggca taaacatcgt cgccagctct tgcgccgaca
     6181 acatatccgg cgcgataccg tcctgttcca gcctcatttc ccgataagcc ttcggcgtat
     6241 aatgcccgcc gtcaggatgt cggggcagct cgccgtgcgg gcggttgttg tattcgtcga
     6301 tacacttgac cacatccgcg ataaaacgcg accagctcgg cagttttttc aaatatttct
     6361 gttgttcctc cgttaaatcc ttgccttttt ccaaagcatt aaacgcactt tccatcttgc
     6421 ggtacatcag gttcttcgta ctgctgtcca ttcctgcgcc cgcaaacgtc tcatactggc
     6481 gcgccatctc aatcagattg tctttccacc atcgctcaat gatgccgcgt ccttgcgggt
     6541 tgcccacgat acccgtttca tgccggatac ccaatcggga cgtaatacct gtgatttcat
     6601 ggtctatcgt cttgccggtt tggccgccgc cgttatccga gtaatagata atcggcaaac
     6661 caaaatgctt gaccccgata cgcagagcgt ccgataccgc cacacaactt tcagcaagag
     6721 agaccgaaaa cccgaccaca aaccgcgtac aaccatcaat aatcaccgtc acttccggct
     6781 taaacggcct gccgtgtaca gggtgcgcca ccttcgcctt aaagctgtgg ccgtcgccga
     6841 tccaaacatc gttcggcttc aaagcccccc aatcacgttt cacataaggc agcagcgatt
     6901 tataagccgc ccccgttttc ctgccgcgct cctgcataat cagcggcagc ttgtcccaaa
     6961 cgcgacgcac catactcaaa ttaggcacat cattgaccgg catattttcc gcttcagccc
     7021 actgcacaaa tcggcggtaa ctgtgcgcca gcttcggagc tgaagggatg ttgtgaaact
     7081 gcataaacat cggcaaccaa ccgtagctct caatcggctt gaccgccttc gtcgtcttcg
     7141 gagccaaagc aaccaaccgc tccgtcgcgt tttccgcttt caaataagca gaaatccagc
     7201 cgtctaaagt acgttcgcca acctttgccg tccggctgcg gtcattggcc ttttccaagt
     7261 tcccaagcgt gaccgcgtcc aatttacttt ctgccagcaa gcccaaaaac tgagccaccg
     7321 cagcctttgc agagcaaccg tattggtatt taatccccaa taccgccgcc accaccgcac
     7381 atcgcgcatt cgccaccgac cgttgtttct cgttcaacag cttggccgct tcagccagtg
     7441 cctgagccga catcgccgtc cccggtctga cttggggcag cattttcggc atcttctccg
     7501 ccagctcgtc cgactgccgt ttcatgatgg ctgctcggat ttcggcaggg agggcatatt
     7561 caacaccacc acccttacct tgacgccttc tcgtttgcca accatccctt tgcgcttttt
     7621 ttctcagccc tattactgtt cttggcatat ttggcaaccc aaaattaagc aggcttttga
     7681 ggtccatata tttcatttca acccactccg agcatctctt tcaattcagc tatctttttg
     7741 tctcgacaat ctgttttctt gtaatgcgga aaaacttcaa ctaaatcttt ttgaatcact
     7801 ttcgcgattg cttccgcaat tcttttgctt cctcgtccat ttcttatgac ctcagaaaca
     7861 gattggttag ttacccctaa agccgaagcc aacattcttg ccgatatatt tttttcttct
     7921 aaggatttat agatttcgtt cgcttgcata atgcctccat gatagaatcc attacttacc
     7981 ttacaggctt taatgcctgc cttaactgtt acttggatga tatacacaaa atatttggta
     8041 taccaaatat atttggcaat attttgcgat gtttttatgg aacgcattga tttagcattg
     8101 aatttagttg aagagagaag ccgacttgga tactctcgaa agaattttgc tgagcaaact
     8161 ggatgcagtg cagaaagttt gagactgtat gaaagcgggc aggtcaacat tcctgcggac
     8221 tttttacttg ctgctgtcca attaggggtg gatattcaat ttgtctttac aggcattcat
     8281 tcggcaaatt taaatgctgt ttcagacgac cttaataaaa aattggacga cgctattggc
     8341 aaatcaaacg ttgagaatca gattaacggc aacgtcagta acgctgttat cgcctcatct
     8401 ggttcggttg ttcatcaaat taatacccaa aatcacgtca tcagaacccg tgtcgattca
     8461 aaacccggca aggaacatat aacgcttgag caagcttcaa agctgcaaca acttgttaaa
     8521 caagttgccg cagcagaaga gattgccaaa cggtcgccaa aatcaatccg tgcaatttgg
     8581 gctagtctga atgctcactg taaagttcca agttacaaac taatcgcatt gagcgattac
     8641 gacaaagcag aaacttatct cagaaaatgg ctgggtaggt tgagcaatac agcaacatca
     8701 aagaacaacg atcccgactg gcgaaaaaag aaatacgctt atatcaaatt aaatgtaaaa
     8761 cagcttgagc ttgaagattg gttgaaaagt tacctcgaaa aaaatttctc agtagaaagc
     8821 ctgactgaat taagtgatga agatttgcaa aaaacatatg cagcagtatc gactaaaaaa
     8881 cggaaaaaat aggcttaaac atgaaactcc gcctttaaat tcaagtttca tgtttagctt
     8941 atggtcttca gatgctttgt ttttttagat gtatgatatt aaaagatttt ttcaaacatg
     9001 gaactattat acaagttcca tgttcagttt ctagttaaag ccttttataa acattctaat
     9061 caaccacgcc gaaaccgagc cgcgcgacgg cctatatgtc ttgcgtatag gcaatgacct
     9121 ctttgtcaaa cgtgtgcaac gtataccggg caaactgctt gtaacgtctg aaaatccacg
     9181 ttacgcaccg tttgaaatag atttgagtaa tacccaagac gacatcgcca tcataggccg
     9241 tgttgagtgg tatggccgga gtattcccca caggaaaacg tcgctctgtt ccgccacaac
     9301 ggcgaaatcc tgttgagcgg catcaacatc aaactcaaaa acggcaactc cctactgata
     9361 cgcggcccga gcggttgcgg caaaacttcg ttgctgcgcg cgctggcggg gctttggccg
     9421 ttcggcagca gcggcaaagt cagccatccg ccgcatcaag acatcctctt cctgccgcaa
     9481 cgtccgtaca cggcacaagg cagtctgcgc gatgcgattt gttaccctgc catcgacaaa
     9541 caacatccgg aactgatcga agccatgaat acctgccgat taggttatct ggttgataaa
     9601 ttagataaaa ccgatgactg gcaacacaaa ctctccccag gcgaactgca acgtgttgcc
     9661 ttcgtccgcg ccctactctc gcagcccaaa gtcatcttgc tcgatgaagc taccgccgct
     9721 ttggacgaac cgaccgaagc catgctctac cgcgccttaa agcaaaaact gcccgacagc
     9781 atcatcatca gtatcggcca ccgcagcacg ctcaacgcgt tccacaatat gcacctcgat
     9841 gtcggcaacg ttgcctgcgg ctgaacgatg ccgtctgaag ccgttttcag acggcatcgt
     9901 caaattggaa aggcgcgcga aaacaacgta caataaacct atctgccaac ctctgaaatg
     9961 ctgcaccgtg aaccagctta tttttgattt tgccgcacac gactatccaa gtttcgacaa
    10021 attcctcggc acggaaaatg cggagctggt ctatgtcctc caacacaaac acggacagtt
    10081 tatctatgtc tggggtgaag aaggcgcggg aaaaagccac cttttgcagg catgggtcgc
    10141 acaggcactc gaagccggca aaaacgccgc ctatatcgat gccgcctcca tgccgctgac
    10201 cgatgccgcg ttcgaggcgg aataccttgc cgtcgatcaa gtcgaaaaac tgggcaacga
    10261 agaacaagcc ctgctttttt ccatcttcaa ccgcttccgc aacagcggca aaggcttttt
    10321 gctgctcggt tcggaataca cgccccagca gcttgtcatc cgcgaagatt tgcggacgcg
    10381 tatggcatac tgcctcgttt acgaagttaa gcccctaacc gaccaagaaa aaatcgacgc
    10441 gctcgccagt atggcggcgg cacgccaagt aaccgttgat tccgaaattt tcgaatacct
    10501 gctcaaacac tggcggcgcg atatggacag cctgatgatg atgctcgaca cgctggacaa
    10561 ctacgccgtc acgatgggca aacgcatcac cctgccgctt ttgcgccagc ttttgaaaca
    10621 acaggaaacc caatgaaaaa cctcgccatc ttcgacctcg acaacaccct catcaacacc
    10681 gattccgacc acgcctggcc gcaatacctc atcaaaaaag gcttggttga cgctgccgaa
    10741 accgaagcgc aaaacgaaaa attctaccgc gactaccaaa acggctgcct cgacatcgac
    10801 gcattcctca aattccacct cgccccgctc gcccgctaca gcaaagaaga gctggcggaa
    10861 tttcaccgcg aatttatggc gaaatacatc atcccccaca tctcgcctat gcagcgtatg
    10921 ctggtgcaga gccaccaaat ggcaggcgac gaaaccctcg tcatctcctc aaccaacgag
    10981 ttcatcatca cccccgtctg ccaccttttc ggcatcacca acatcatcgg cacacaactc
    11041 gaaaccggtt ctgacggccg ctacaccggc aattacatcg gcacgcccag cctcaaagaa
    11101 ggcaaaatta cccgcctgaa ccaatggctt gccgaacgcg gcgaaacgct ccaaagctac
    11161 ggcaaaacct atttttacag cgactccaga aacgacctgc cgctgctgcg cctcgtcagc
    11221 gaacccgtcg ccgccaaccc cgatgccgag ctggaaaaag aagccaaaga aaaaggctgg
    11281 ccggttttga atttcaaatg acgcaatgcc gtctgaagcc cgattcggcg ttcagacggc
    11341 attggggctg aaatcccaaa aactcaaagc cacaggaatt tatccggaaa aacaaaaaac
    11401 acaggaattc atcgggaaaa acaacaatct ttccaccgtc attcccacga aagtgggaat
    11461 cttgatccgt ccgcacggaa acttatattt cgtcatttgc acccgacata attcaatact
    11521 ttattttgca ataaattaac ggatgctgac aaattagatt ggattaatta ccctattatc
    11581 catattgggt tatcgggttg ctaattgagc agagcgtagc aaaccataaa gtgagtgttt
    11641 ccacccactc tgcatttact atgaagtggt tattaaatat gataatgaga cctattaaat
    11701 ttagtatggt aaatacgtta ttatttattg ttatatgtag ttcatttttt gatctgctcg
    11761 ttcaattatg tacaatttta tttcatagcc aaaaaatata ctttattaca ttatttttat
    11821 tatttatttt taattttgtt acaaaatcta tctatatggc aattatttat cctattttat
    11881 atttttttac gataaaaaaa tattatcctt actctaggaa agtgataatt ctattatcat
    11941 tagcattatc tatatatttt agttttatgg acttttactt tttttccata tattcagata
    12001 accttagcta tgaaacggag cctttacatt tatacatccc tattattatt aattttttct
    12061 cacttttagt ttctaatttt attttatctt ttatcaacaa gtaaatgtat atacaaacta
    12121 caatccaaaa gatcctaagc aaaccaccaa tcccacacca cccttaccgg ttcaaatccg
    12181 cacaaaaacc cacatcccgt cattcccacg aaagtgggaa tctaggacgt atagtggatt
    12241 aacaaaaatc aggacaaggc gaccaagccg cagacagtac aaatagtacg gaaccgattc
    12301 acttggtgct tcagcacctt agagaatcgt tctctttgag ctaaggcgag gcaacgccgt
    12361 actggttttt gttaatccac tataaaatct aaagaaacct tttttcccga taagtttc
//
LOCUS       DAXISH010000060        12415 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.060, whole genome shotgun sequence.
ACCESSION   DAXISH010000060 DAXISH010000000
VERSION     DAXISH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12415
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.060"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(84..737)
                     /locus_tag="ACFOV4_001704"
     CDS             complement(84..737)
                     /locus_tag="ACFOV4_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004730 - pseudouridylate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01621 family pseudouridine synthase"
                     /protein_id="HFC7619671.1"
                     /translation="MLEILFRHQDFVAINKPGGISVHQDSGETGLARTLAIQLGVERV
                     WLLHRLDKQTSGILLFALNKESASALSGQFAGKSIKKTYLALSDRKPSKKQGWIKGGM
                     EKSRCGMWKLTRNTENIAVTRFHSISIAEKLRLFILEPHTGKTHQLRVAMKSLGSPIL
                     GDSLYGGTESETMFLYAWKIQFAYQNRQIEIVAPLKNEWQTENISHALEEFYMAKAG"
     gene            complement(769..1281)
                     /gene="coaD"
                     /locus_tag="ACFOV4_001705"
     CDS             complement(769..1281)
                     /gene="coaD"
                     /locus_tag="ACFOV4_001705"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFC7619672.1"
                     /translation="MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINP
                     DKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLVHYAREVDAGFIVRGIRSASDYE
                     YERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYE
                     KILAEHQHEN"
     gene            complement(1405..2088)
                     /locus_tag="ACFOV4_001706"
     CDS             complement(1405..2088)
                     /locus_tag="ACFOV4_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HFC7619673.1"
                     /translation="MQHDVYDYTAHTVSKNTVLQKTYRLLGFSFIPASAGAALAANAG
                     FNFYAAFGSRWIGFAVVLAFFYGMIHFIEKNRYSNTGVTLLMVFTFGMGVLIGPVLQY
                     ALHIADGAKIVGIAAAMTAAVFLTMSALARRTRLDMNALGRFLTVGAVILMVAVVANL
                     FLGIPALALTISAGFVLFSSLMIMWQVRTVIDGGEDSHISAALTLFISLYNIFSSLLN
                     ILLSLNGED"
     gene            complement(2245..2511)
                     /locus_tag="ACFOV4_001707"
     CDS             complement(2245..2511)
                     /locus_tag="ACFOV4_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HFC7619674.1"
                     /translation="MARMVFCVKLNKEAEGMKFPPLPNELGKRIFENVSQEAWAAWTR
                     HQTMLINENRLSLADPRAREYLAQQMEQYFFGDGADAVQGYVPQ"
     gene            complement(2584..3054)
                     /gene="rlmH"
                     /locus_tag="ACFOV4_001708"
     CDS             complement(2584..3054)
                     /gene="rlmH"
                     /locus_tag="ACFOV4_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFC7619675.1"
                     /translation="MNITVLAVGTKMPRWVDEAVAEYAKRFGRDVAYALKEIKPEKRG
                     AGVNAAQGMAAEEKRILEAVPQGAFLVVLDERGKAPTSVELAEHLKSWRQNGEHVCFV
                     IGGADGMTDRLKQQARMMMRLSSLTLPHGMVRVFLTEQLYRAVSILHNHPYHRE"
     gene            complement(3108..3494)
                     /gene="rsfS"
                     /locus_tag="ACFOV4_001709"
     CDS             complement(3108..3494)
                     /gene="rsfS"
                     /locus_tag="ACFOV4_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFC7619676.1"
                     /translation="MNEQELQDLQKMVGVAVNALEDIKAKDISVLETQDKTSLFARMI
                     IASGDSTRQVKALANNVAVDLKEAGFEILSTEGDSGEWTLVDAGDLVVHVMLPAVRDF
                     YDIDTLWGGEKPSFHAGMQKPWHAAD"
     gene            complement(3553..4146)
                     /gene="nadD"
                     /locus_tag="ACFOV4_001710"
     CDS             complement(3553..4146)
                     /gene="nadD"
                     /locus_tag="ACFOV4_001710"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFC7619677.1"
                     /translation="MKKIGLFGGTFDPIHNGHLHIARAFADEIGLDAVVFLPAGGPYH
                     KDAASASAADRLAMVELATAEDARFAVSDCDIVREGATYTFDTVQIFRQQFPSAQLWW
                     LMGSDSLMKLHTWKKWQMLVRETNIAVAMRQGDSLHQTPRELHAWLGKSLQDGSVRIL
                     SAPMHNVSSTEIRRAGVSDGIPPAAARYIREHGLYEK"
     gene            complement(4143..4742)
                     /locus_tag="ACFOV4_001711"
     CDS             complement(4143..4742)
                     /locus_tag="ACFOV4_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HFC7619678.1"
                     /translation="MSELDNILAHNRQFVESGEYEKYFTDKYPERGLAVLSCMDARII
                     GLLPDALGLKNGDAKLIKNAGALVTHPWGSVMRSLLVAVFELKVREIMVIAHHDCGMQ
                     GLNAEEFLGRVRESQIPEDRIETLRYAGIDLDGWLTGFDNVEDSVRHTVDLIRNHPLM
                     PRHIAVHGLVIHPVTGKLTLVVDGSVSDGMDLSEGMETS"
     gene            complement(4771..6312)
                     /locus_tag="ACFOV4_001712"
     CDS             complement(4771..6312)
                     /locus_tag="ACFOV4_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFC7619679.1"
                     /translation="MDGRRWVVWGAFALLPSAFLAVMVVAPLWAVAAYDGLAWRAVLS
                     DAYMLKRLAWTVFQAAATCVLVLPLGVPVAWVLARLAFPGRALVLRLLMLPFVMPTLV
                     AGVGVLALFGADGLLWRGRQDTPYLLLYGNVFFNLPVLVRAAYQGFVQVPAARLQTAR
                     TLGAGAWRRFLDIEMPVLRPWLAGGVCLVFLYCFSGFGLALLLGGSRYATVEVEIYQL
                     VMFELDMAVASVLVWLVLGVTAAAGLLYAWFGRRAVSDKAVSPVMPSPPQSVGEYVLL
                     AFAAAVLSVCCLFPLLAIVVKAWSAGESWRVLMESETWQAVWNTLRFSAAAVYAAAVL
                     GVVYAAAARRSAWMRGLMFLPFMVSPVCVSAGVLLLYPQWTASLPLLLAMYALLAYPF
                     VAKDVLSAWDALPPDYGRAAAGLGANGFQTACRITFPLLKPALRRGLTLAAATCVGEF
                     AATLFLSRPEWQTLTTLIYAYLGRAGEDNYARAMVLTLLLSAFALGIFLLLDNGEGGK
                     QTETL"
     gene            6705..8090
                     /locus_tag="ACFOV4_001713"
     CDS             6705..8090
                     /locus_tag="ACFOV4_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003705069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFC7619680.1"
                     /translation="MDGWTQTLSAQTLLGISAAAIILILILIVKFRIHALLTLVIVSL
                     LTALATGLPTGSIVNDVLVKNFGGTLGGVALLVGLGAMLGRLVETSGGAQSLADALIR
                     MFGEKRAPFALGVASLIFGFPIFFDAGLIVMLPIVFATARRMKQDVLPFALASIGAFS
                     VMHVFLPPHPGPIAASEFYGANIGQVLILGLPTAFITWYFSGYMLGKVLGRTIHVPVP
                     ELLSGGTQDNDLPKEPAKAGTVVAIMLIPMLLIFLNTGVSALISEKLVSADETWVQTA
                     KIIGSTPIALLISVLVALFVLGRKRGESGSALEKTVDGALAPVCSVILITGAGGMFGG
                     VLRASGIGKALADSMADLGIPVLLGCFLVALALRIAQGSATVALTTAAALMAPAVAAA
                     GFTDWQLACIVLATAAGSVGCSHFNDSGFWLVGRLLDMDVPTTLKTWTVNQTLIALIG
                     FALSALLFAIV"
     gene            8110..8628
                     /locus_tag="ACFOV4_001714"
     CDS             8110..8628
                     /locus_tag="ACFOV4_001714"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase, GntK/IdnK-type"
                     /protein_id="HFC7619681.1"
                     /translation="MTTHFVVMGVCGCGKTTAALSLQKHLGQCPYAEGDEFHTQANRD
                     KMGAGIPLTDEDRYPWLGNLRDWMTQQAQNGANHTIVTCSALKRGYRDILRGAEGKAA
                     FIHLSPPQDINLERMMSRKGHYMKAGMLDSQLEILEELGEGEYGVKIANPGTPEAVEA
                     DILNWVASENLL"
     gene            complement(8967..9884)
                     /gene="thrB"
                     /locus_tag="ACFOV4_001715"
     CDS             complement(8967..9884)
                     /gene="thrB"
                     /locus_tag="ACFOV4_001715"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HFC7619682.1"
                     /translation="MSVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTT
                     SGRYVLTVFEVLKQEELPFFLELNRHLSMKGVAVAAPVARKDGRLDSVLAGKPACLVA
                     CLKGSDTALPTAEQCFHTGAMLAKMHLAAADFPLEMENPRYDAWWTEACTRLLPVLSQ
                     DDAALLCSEIDALKDNLGNHLPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMY
                     DLAIAVNDWARTADNKLDEALKKVFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSR
                     LLDFHFPQAGEMTFIKDPNAFRNLLLSLD"
     gene            complement(9921..10649)
                     /gene="ubiG"
                     /locus_tag="ACFOV4_001716"
     CDS             complement(9921..10649)
                     /gene="ubiG"
                     /locus_tag="ACFOV4_001716"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="HFC7619683.1"
                     /translation="MGGKMSDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLR
                     LDYIDGHADLCGKRVLDVGCGGGILAESMARRGAAFVKGIDMAEQSLETARLHAALNN
                     VADIEYECIRVEDLAEAEPHSFDVVTCMEMMEHVPDPAAIVRACAKLVKPDGMVFFST
                     INKNPKSYLHLIVAAEYLLKFVPKGTHDWKKFIAPAELARMCRQAGLDVADTKGMTYH
                     VLSQTYALCDSTDVNYMFACRPAF"
     gene            10801..11865
                     /locus_tag="ACFOV4_001717"
                     /pseudo
     CDS             10801..11865
                     /locus_tag="ACFOV4_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235268.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015173 - aromatic amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015801 - aromatic amino acid transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter"
     gene            11945..>12415
                     /locus_tag="ACFOV4_001718"
     CDS             11945..>12415
                     /locus_tag="ACFOV4_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFC7619684.1"
                     /translation="MKLKIDIATNNFKHGGGTERYTLDLVKGLNRQNITPAVYATKFD
                     HGIPEYAMIEPHLVDQHRTLKKLRSFLFSSRLAQTRKNSAAKLIACHHADYADLLICG
                     GTHLGYLHHMAQKPNLLDRLAIRRNRSNYATAKLIMAHSHMMQRELVGLYGVPPE"
BASE COUNT         2863 a         3715 c         3144 g         2693 t
ORIGIN      
        1 tgaagagatt tgcagtcaac cgttttcttg aaaaattttt ataaaaatat ttatcatatt
       61 gtttataaat taatttatat ttattaacct gcttttgcca tataaaattc ttccagcgca
      121 tgagagatat tttcagtctg ccattcgttt tttaagggtg caacaatttc gatttgtcgg
      181 ttttggtagg caaattgtat tttccatgca tacagaaaca tggtttcgga ttctgttccg
      241 ccgtataagc tgtcgcccag aatcggactg cccaaacttt tcatcgccac tctcaattgg
      301 tgcgttttgc ccgtatgcgg ttctaggatg aacagccgca gtttttcggc gatactgatg
      361 ctgtggaatc gggtaacggc gatattttct gtattgcgcg tcaacttcca cattccacat
      421 ctggattttt ccattccgcc tttaatccaa ccctgctttt tggacggctt gcggtcggac
      481 agtgccaaat aggttttttt gatgcttttg ccggcaaact gtccgctaag ggcggacgcg
      541 ctttctttgt tgagggcaaa cagtaaaatg ccgctggtct gtttgtccaa tcggtgcagc
      601 agccacacac gctctacgcc caactgtatg gcgagtgttc gggccagtcc ggtctcgccg
      661 ctgtcttggt ggacggatat gccgcccggt ttgttgatgg cgacgaagtc ttgatggcgg
      721 aacaaaattt ccaacatatc catatatgcc ttgcaaaaat agaagggttc aattttcgtg
      781 ttgatgttcg gcaaggattt tttcgtacac agcttgcggc acgtagcggt ggatcgtttc
      841 cgtccagcct tccggcccga ccagtccttt gaccatagtg gacgacactt cggcgatttc
      901 gcgcggcggc atgaggaata cggtggatat ttcgggggcg aggtcgctgt tgatatggcg
      961 catggaacgt tcgtattcgt aatccgaagc agaacggatg ccgcgcacga tgaatcctgc
     1021 atctacctca cgggcgtaat gcaccaaaaa tcggttttca aatacatcgg ttctgacgtt
     1081 gggaaacatt ttagtaatat cgcacaacat atcctgcctt tcagcgacgg tataggtgct
     1141 gcgtttgtcg gggttaatgc cgatggcgac gatgagttcg tcaaacatag attgcgcctg
     1201 ccgtatcatc cacagatgcc ccaatgtggg cggatcgaaa ctgccggcat aaacggcgcg
     1261 gcgcggtgta ttcggtaaca tttgattcct cccggcttca tagtcggctg tgtgttggtg
     1321 cgtgtgcatc cgtattgtat gcccaaagta aaatgccgtc tgaagcattt tcagacggca
     1381 tagtcggacg gcgttttacc ggcatcaatc ctcgccgttt aaagacaaca ggatgttcag
     1441 caggctgctg aagatgttgt aaagcgagat aaacagtgtc agtgccgcgc tgatgtggct
     1501 gtcttcgccg ccgtcgatga cggtgcgtac ctgccacata atcattaagg aactgaacaa
     1561 gacaaaaccg gcggaaatgg tcagggcgag tgcgggaata cccaaaaaca gattggcaac
     1621 cacggcgacc atcagaatga ccgcacctac ggtcaggaag cgtccgagcg cgttcatatc
     1681 gagccgggtt cggcgcgcca aggcggacat cgttaaaaag acggcggcgg tcatcgcggc
     1741 ggcaatgccg acgattttcg caccgtcggc aatatggagc gcgtattgca gcacggggcc
     1801 gatcaatacg cccataccga atgtgaatac catcagcagg gtaacgccgg tattgctgta
     1861 acggtttttc tcgatgaagt ggatcatacc gtagaaaaac gccaacacga cggcaaaccc
     1921 tatccagcgc gaaccgaagg cggcgtaaaa attgaaaccg gcattggcgg caagtgccgc
     1981 gcctgcggaa gccggaataa atgaaaatcc gagcaggcgg taggttttct gcaggacggt
     2041 gtttttagaa accgtatgcg cggtgtagtc gtaaacgtcg tgttgcatat catctgctcc
     2101 tgaaagcgcg gttgggaata atgggggatt ttaacattgc ccaatgtcaa aatttgtccg
     2161 gttgcgtgaa gataaagttg tccggcgtat tttaaaggcc gtctgaagca gtttcggaca
     2221 gcctgtgttc aaaacggaaa accgttattg cggaacgtat ccctgaacgg catccgcgcc
     2281 gtcgccgaag aaatactgct ccatctgctg agccaggtat tcgcgcgcgc gcggatcggc
     2341 gaggcttaaa cggttttcgt taatcagcat cgtttggtgg cgcgtccacg ccgcccacgc
     2401 ttcttgcgat acgttttcaa aaatgcgctt gcccaattcg ttgggaagcg gcggaaattt
     2461 catgccttcg gcttctttgt tgagcttgac gcagaatacc atgcgtgcca tagcggattc
     2521 ctttgctgtg ttcagaaata acggggtgat tttaaccgat tagggatacg gacaaaagcc
     2581 ttcttattcc cgatgatagg gatggttgtg caggatggaa acggcgcggt agagctgctc
     2641 ggtcagaaag acgcgcacca tgccgtgcgg cagggtgagg ctggacaggc gcatcatcat
     2701 gcgggcttgt tgtttgaggc ggtcggtcat gccgtccgcg ccgccgatga cgaagcagac
     2761 gtgttcgccg ttttgccgcc agcttttgag gtgttccgcc agctcgacgg aggtcggcgc
     2821 tttgccgcgt tcgtcaagaa cgacgaggaa cgcgccttgc ggaacggctt cgaggatgcg
     2881 tttttcttcc gccgccatac cttgggcggc attcacgccc gcgccgcgtt tttcgggttt
     2941 gatttctttg agtgcgtagg cgacgtcgcg tccgaagcgt ttggcgtatt cggcgacggc
     3001 ctcatcaacc cagcgcggca ttttggtgcc gactgccaaa acggtaatgt tcaatgcttt
     3061 ctcccttaca ggaaaatgcc gtctgaacat tcagacggca tcgggaatca gtctgccgcg
     3121 tgccacggct tctgcattcc ggcgtgaaaa ctcggtttct cgccgcccca aagggtgtcg
     3181 atatcataga agtcgcgcac ggcggggagc ataacgtgga cgacgaggtc tcctgcatca
     3241 acgagcgtcc attcgccgct gtctccttcg gtactgagga tttcaaaacc ggcttctttc
     3301 aaatcgacgg caacgttgtt ggccagtgct ttgacttggc gcgtactgtc gccgctggcg
     3361 ataatcattc tggcaaacag cgaagttttg tcttgcgttt cgagaacgga aatgtctttg
     3421 gctttgatgt cttcgagggc gttgacggcg accccgacca ttttttgcag gtcttgcagt
     3481 tcttgttcgt tcattatttt cctaacggga tgttttcaga cggcattata gccgtttctt
     3541 actgatttga ctttattttt catacaaacc gtgttcgcgg atgtagcgtg cggcggcagg
     3601 tgggatgccg tctgaaacac cggcgcggcg gatttccgtt gacgacacat tatgcatcgg
     3661 ggcggacaag atgcggacgc tgccgtcctg aagggacttg cccagccacg cgtgcagttc
     3721 gcgcggggtt tggtgcaggc tgtcgccctg ccgcatggcg acggcgatat tggtttcgcg
     3781 cacgagcatc tgccattttt tccatgtgtg cagcttcatc aggctgtcgc tgcccatcag
     3841 ccaccagagt tgcgcggatg ggaactgctg gcggaagatt tggacggtat caaaagtata
     3901 ggttgcacct tctcggacga tgtcgcaatc gctgacggca aaacgcgcgt cttctgccgt
     3961 cgccagttcg accatggcaa ggcggtcggc ggcggaagcg gaggctgcgt ctttgtgata
     4021 cgggccgcct gccggcagga aaacaaccgc gtccaagccg atttcgtcgg caaaggcgcg
     4081 ggcgatgtgg agatgcccgt tgtgtatcgg gtcgaaagtg ccgccgaaca gtccgatttt
     4141 cttcatgatg tttccattcc ttccgataag tccatgccgt ctgaaacact gccgtccaca
     4201 accagcgtca gtttgccggt aacgggatgg atgaccagtc cgtgaacggc gatatggcgc
     4261 ggcatcagcg gatggttacg gataaggtcc accgtgtggc gcacgctgtc ttcgacgttg
     4321 tcgaaaccgg tcagccagcc gtcgaggtcg ataccggcat aacgcagggt ttcgatacgg
     4381 tcttcgggaa tctggctttc ccggacgcgc ccgaggaatt cttcggcatt cagcccctgc
     4441 ataccgcaat cgtgatgggc gatgaccata atctctctga ccttcaattc aaacacggca
     4501 accaaaagac tccgcatcac cgaaccccac gggtgcgtaa ccagcgcgcc ggcattttta
     4561 atcagcttgg catcgccgtt tttcaaaccc aacgcgtcgg gcagcagccc gataatccgc
     4621 gcatccatac aggacaaaac tgccagcccg cgttcggggt atttgtcggt aaagtatttt
     4681 tcatattcgc ccgactcgac aaactgccgg ttatgggcaa ggatgttatc caactcgctc
     4741 attttgccgt cctctgaaaa agggttcaca ttataacgtt tccgtctgtt ttccgccttc
     4801 gccgttgtcc aacagcagga aaatgcccag cgcgaacgcc gacaacagca atgtcaacac
     4861 cattgcccgc gcataattat cctcacccgc acgccccaaa taggcataaa tcaaagtcgt
     4921 cagcgtctgc cactcgggac gcgacaggaa caaggttgcc gcaaattcgc ccacgcaggt
     4981 tgccgccgcc aaagtcagac cgcgccgcaa cgccggtttc aagaggggga acgtgatgcg
     5041 gcatgccgtc tgaaagccgt ttgcacccaa acccgccgcc gccctgccgt aatccggcgg
     5101 cagtgcatcc caggctgata aaacatcttt tgccacaaac ggatacgcca gcagcgcata
     5161 catcgccagc agcagcggca acgaagccgt ccactgcgga taaagcagca gcacgcccgc
     5221 cgaaacacaa accggcgaca ccataaacgg caaaaacatc agcccgcgca tccacgccga
     5281 ccgccgcgcc gccgccgcat acaccacacc caaaaccgcc gccgcataca ccgccgccgc
     5341 cgagaagcgc aaagtattcc acaccgcctg ccacgtttca ctttccatta acacacgcca
     5401 cgattcgccg gccgaccacg ctttcacaac aattgccaac aaaggaaaca ggcagcacac
     5461 agacaacacc gccgccgcaa acgccagcag cacatattcc ccgaccgact gcggcggcga
     5521 cggcatcaca ggggaaaccg ccttatccga aaccgcgcgc ctgccgaacc acgcatacag
     5581 caaccctgcc gccgccgtta cccccaacac cagccacacc agcaccgaag caaccgccat
     5641 atcgagttcg aacatgacca actggtaaat ttccacttcg accgtggcat aacggctgcc
     5701 gcccagcagc aatgccagcc cgaaccccga aaaacaatac aggaagacaa ggcacacgcc
     5761 gccggcaagc cacgggcgca aaacgggcat ttcaatgtcc aaaaaccgcc gccacgcccc
     5821 cgcgcccaac gtccgtgccg tctgaagccg tgccgcaggc acttgcacaa acccctgata
     5881 cgccgccctg accaacacag gaaggttgaa aaacacattg ccgtacaaca acagatacgg
     5941 cgtatcctgc ctgccgcgcc acaacagccc gtccgccccg aacagggcca gcacgcccac
     6001 gcccgccacc aacgtgggca tcacaaaagg cagcatcagc aggcgcagca ccaaagcccg
     6061 ccccggaaac gccagccgcg ccagcaccca cgcgacaggc acgcccaaag gcagcaccag
     6121 cacacaggtt gccgctgcct gaaataccgt ccacgccaaa cgtttgagca tataggcatc
     6181 cgacagcacc gcgcgccacg ccaaaccgtc atacgccgcc accgcccaca aaggcgcaac
     6241 gaccattacc gccaaaaaag ccgaaggcag cagggcaaaa gcaccccata ccacccaacg
     6301 ccgtccatcc atcgccttcc ccacttgaaa cactgatgtt gcgattgtac ccaaaagccc
     6361 ccacataccg tatatttcaa tccgactaca taccgtatcc gccttcctcc cgccgtctga
     6421 aatatagtgg attaacaaaa atcaggacaa ggcgacgaag ctgcagacag tacaaatagt
     6481 acggaaccga ttcactcggt gcttcagcac cttagagaat cgttctcttt gagctaaggc
     6541 gaggcaacgc cgtactggtt tttgttaatc cactataaat cgttcaaata aacaggaata
     6601 taacttcaga caaacaactt accgcccgat ttgtgctatc gttttcgcac aacttaaaaa
     6661 aacctgacaa ttttgtactt ttattacaga gaaaggcttt acaaatggac ggctggacac
     6721 agacgctgtc cgcgcaaacc ctgttgggca tttcggcggc ggcaatcatc ctcattctga
     6781 ttttaatcgt caaattccgc atccacgcgc tgctgacact ggtcatcgtc agcctgctga
     6841 cggctttggc aaccggtttg cccacaggca gcattgtcaa cgacgtactg gtcaaaaact
     6901 tcggcggcac gctcggcggc gtggcgcttc tggtcggcct gggcgcgatg ctcggacgtt
     6961 tggtcgaaac atccggcggc gcacagtcgc tggcggacgc gctgatccgg atgttcggcg
     7021 aaaaacgcgc accgttcgcg ctgggcgttg cctcgctgat tttcggcttc ccgattttct
     7081 tcgatgccgg actaatcgtc atgctgccca tcgtgttcgc caccgcacgg cgcatgaaac
     7141 aggacgtact gcccttcgcg cttgcctcca tcggcgcatt ttccgtcatg cacgtcttcc
     7201 tgccgcccca tccgggcccg attgccgctt ccgaatttta cggcgcgaac atcggccaag
     7261 ttttgatttt gggtctgccg accgccttca tcacatggta tttcagcggc tatatgctcg
     7321 gcaaagtgtt ggggcgcacc atccatgttc ccgttcccga actgctcagc ggcggcacgc
     7381 aagacaacga cctgccgaaa gaacctgcca aagcaggaac ggtcgtcgcc atcatgctga
     7441 ttcccatgct gctgattttc ctgaataccg gcgtatcggc cctcatcagc gaaaaactcg
     7501 taagtgcgga cgaaacctgg gttcagacgg caaaaataat cggttcgaca ccgatcgccc
     7561 ttctgatttc cgtattggtc gcactgtttg tcttgggacg caaacgcggc gaaagcggca
     7621 gcgcgttgga aaaaaccgtg gacggcgcac tcgcccccgt ctgttccgtg attctgatta
     7681 ccggcgcggg cggtatgttc ggcggcgttt tgcgcgcttc cggcatcggc aaggcactcg
     7741 ccgacagcat ggcggatttg ggcattcccg tccttttggg ctgtttcctt gtcgccttgg
     7801 cactgcgtat cgcgcaaggt tcggcaaccg tcgccctgac caccgccgcc gcgctgatgg
     7861 ctcctgccgt tgccgccgcc ggctttaccg actggcagct cgcctgtatc gtattggcaa
     7921 cggcggcagg ttcggtcggt tgcagccact tcaacgactc cggcttctgg ctggtcggcc
     7981 gcctcttgga catggacgta ccgaccacgc tgaaaacctg gacggtcaac caaaccctca
     8041 tcgcactcat cggctttgcc ttgtccgcac tgctgttcgc catcgtctga cagacggaaa
     8101 ggatagtaaa tgactacgca ttttgtcgtt atgggcgtat gcggctgcgg caagaccacc
     8161 gccgcgctgt ccctgcagaa acacctcggt caatgtccct atgccgaagg cgacgagttc
     8221 cacacccaag ccaaccgcga caagatgggc gcgggtattc cgctgaccga tgaagaccgc
     8281 tatccgtggt tgggcaatct gcgcgactgg atgacgcaac aggcgcaaaa cggtgcgaac
     8341 cacaccatcg taacctgttc cgccctcaaa cgcggctacc gcgacattct gcgcggagcc
     8401 gaaggcaaag ctgccttcat ccacctcagt ccgccgcaag acatcaacct cgagcgcatg
     8461 atgtcgcgca aaggacatta catgaaagca gggatgctcg attcgcaact ggaaatcctc
     8521 gaggaactgg gcgaaggcga atacggggtc aaaatcgcca accccggcac gcccgaagcg
     8581 gtcgaagccg atattctgaa ctgggttgcc tcggaaaacc tgctttgaag caatatgccg
     8641 tctgaagccc gacacaggat gggtttcaga cggcataaac atcgggaaca gaatggatta
     8701 cattgattta tagtggatta acaaaaacca gtacagcgtt gcctcgcctt agctcaaaga
     8761 gaacgattct ctaaggtgct gaagcaccga gtgaatcggt tccgtactat ctgtactgtc
     8821 tgcggcttcg tcgccttgtc ctgatttttg ttaatccact ataaaatgga aaatacccgg
     8881 ctatcgtctc attttcgttt taatcagcca taaaaatgcc gtctgaaacc ctttcagacg
     8941 gcatttctgt caaacgccgg acgcactcaa tccaaactca acagcaggtt gcggaacgcg
     9001 ttcgggtctt tgataaacgt catctcgccc gcctgcggaa aatgaaagtc caacaggcgc
     9061 gacacccaaa aacggatgca gccggcacgt tgggcggtcg ggaaatacgc cttttcttcg
     9121 gcactcaagg ggcgcacgcc ctcataaccg ccgataaaca cctttttcaa cgcctcatcc
     9181 aacttattgt ccgccgtcct tgcccaatcg ttgaccgcaa tcgccaagtc atacataaaa
     9241 ttgccccggc aggcataata gaaatcgatg aaacccgata cctgaccgcc gtcaagcaac
     9301 acattgtctt taaacaaatc ggcatggatg atgcccgaag gcagatgatt gccgagattg
     9361 tcctttaacg catcgatttc ggaacacagc agcgcggcat cgtcttgcga caggacgggc
     9421 agcagccggg tgcacgcctc cgtccaccac gcatcgtaac gcgggttttc catttccaaa
     9481 gggaaatcgg cggcggcaag gtgcattttg gccagcatcg caccggtatg gaaacactgc
     9541 tccgccgtcg gcagcgcggt atccgaacct ttcaggcagg caaccaaaca agccggcttg
     9601 cccgccaaaa cggaatcaag ccggccgtct ttgcgcgcaa ccggcgcggc aaccgccacg
     9661 cccttcatac tcaaatgccg gttaagctcc agaaaaaacg gcagctcttc ctgtttcaac
     9721 acttcaaaca cggtcagcac ataacgtccc gaagtcgtcg tcagaaaata attgctgttg
     9781 gtaatcccct gcgcgatgcc ctgcagggaa acaaattccc ccaaatcgta accgctcagg
     9841 aagccgcgca tttcatcatc ggaaacactg gtatagacag acatatcaac tcacttgctc
     9901 aaaaacgggc aaacccgccg tcagaacgcc ggacggcagg caaacatata attcacatcg
     9961 gtcgaatcgc acagggcata agtttgcgac aacacatggt aagtcatacc cttcgtatcc
    10021 gccacatcca agcctgcctg acggcacatt cgcgccagct cggcaggtgc gatgaatttt
    10081 ttccagtcgt gcgtgccttt ggggacaaac ttcaacagat attccgccgc cacaatcaga
    10141 tgcaggtacg atttcgggtt tttattgatg gtggaaaaaa acaccatgcc gtccggcttg
    10201 accagcttgg cacaagcacg cacgatggcg gcgggatcgg ggacgtgttc catcatttcc
    10261 atgcacgtta ccacatcgaa cgagtgcggt tccgcctcgg caaggtcttc cacgcggata
    10321 cattcgtatt cgatatcggc gacattgttc aaagccgcgt gcaggcgggc ggtttccaac
    10381 gactgctccg ccatgtcgat gccctttaca aacgccgcgc cgcgccgtgc catactttcc
    10441 gccaagatgc cgccgccgca gcccacgtcc aaaacccgtt tgccgcacaa atccgcgtgc
    10501 ccgtcgatat aatccagccg cagcggattg atgtcgtgca aggttttgaa ctcgcccgac
    10561 ttgtcccacc atttgtcggc aatccggctg aatttggcga tttccccctc atcgacatta
    10621 tattttttgt cggacatttt ccctcccatc tgacgaaccg cccactccaa aacccaagat
    10681 tatactatgg aacacaatgc cgtctgaaag ccttttcggg cggcgcggcg caaatgcctt
    10741 acaaatcctt acactttacg gcataatggc ggctcgcttt ttctggcaga aagacaaaat
    10801 atgcccacca aaaccccttc actgttcggc ggcgcgatga ttatcgccgg cacggtcatc
    10861 ggcgcaggta tgctcgccaa cccgaccgcc acatccggcg tatggtttac cggctcgctg
    10921 gccgtgttgc tgtacacctg gttttctatg ctttccagcg gcctgatgat tttggaagtc
    10981 aacacccact atccccacgg cgcaagtttc gacacgatgg tcaaagacct gctcggacgc
    11041 ggctggaaca tcatcaacgg catcgccgtc gccttcgttt tatacctgct cacctacgcc
    11101 tacatcttcg ttggcggcga cctgaccgcc aaaggcttag gcagcgcctt gggcggcaat
    11161 gtttcactca ccgtcggaca actcgtcttc ttcggcatcc tcgccttttg cgtatgggca
    11221 tccgcacgct tggtcgaccg cttcaccagc gtcctcatcg gcggcatggt attaaccttt
    11281 atttgggcaa ccggcggcct gattgccgat gccaaaatgc ccgtcctgtt cgacacccaa
    11341 gcccccgtcg gcaccaacta ctggatttac gccgccaccg ccctgcccgt ctgccttgcg
    11401 tcattcggtt tccacggcaa cgtctccagc ctgctcaaat actttaaagg cgacgcgccc
    11461 aaagtggcta aatccatctg gacgggcaca ctgattgcgc tggtaattta cgtcctctgg
    11521 caaaccgcca tccaaggcaa cctgccgcgc aacgagttcg cccccgtgat tgccgccgaa
    11581 gggcaagtct ccgtcctcat cgaaaccctg tccaaattcg cccaaaccgg caatatggat
    11641 aaaatattgt ccctgttttc ctatatggcg atcgccacct cgtttttagg cgtaacctta
    11701 ggtctgttcg actacatcgc cgacatcttc aaatggaacg acagcgtgtc cggccgcacc
    11761 aaaaccgccg cgctgacctt cctgccgcct ctaatttcct gcctgctctt ccccaccggc
    11821 ttcgttaccg ccatcggcta cgtcggcctg gcggcaaccg tattccggca cacagcgcat
    11881 taccctgctc ctcacgcaca aatcccgccc cgacaaaccg ggacgcaacc ataaaggaac
    11941 aatgatgaag ctcaaaatag atattgcaac caacaacttc aaacacggcg gcggcacgga
    12001 acgctacaca ttggatttgg taaagggtct gaacagacaa aacatcacac cggccgttta
    12061 tgcgacgaaa tttgatcacg gcattcctga atacgccatg atcgaacccc atcttgtcga
    12121 tcaacaccgg acgctgaaaa aactacgctc attcctcttt tcaagccggc tcgctcaaac
    12181 cagaaaaaac agtgccgcca aactgattgc ctgccaccac gccgattacg ccgacctcct
    12241 catctgcggc ggcacacact tgggctacct gcaccatatg gcgcaaaaac cgaacctgct
    12301 cgaccgcctc gccatacgcc gcaaccgcag caactacgcc accgccaaac tgattatggc
    12361 gcattcccat atgatgcagc gcgaactggt cggactatac ggcgttcccc ccgaa
//
LOCUS       DAXISH010000061        12035 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.061, whole genome shotgun sequence.
ACCESSION   DAXISH010000061 DAXISH010000000
VERSION     DAXISH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12035
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.061"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            155..280
                     /locus_tag="ACFOV4_001719"
                     /pseudo
     CDS             155..280
                     /locus_tag="ACFOV4_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(431..1474)
                     /gene="argC"
                     /locus_tag="ACFOV4_001720"
     CDS             complement(431..1474)
                     /gene="argC"
                     /locus_tag="ACFOV4_001720"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HFC7619685.1"
                     /translation="MSKKIKVGIVGATGYTGVELLRLLAAHPDVEVAAVTSRSEAGTA
                     VADYFPSLRGVYGLAFQTPDEAGLEQCDIVFFATPNGIAMKDAPRLIEQGVRVIDLSA
                     DFRIWDIPTWEHWYGMTHAAPGLVSQAVYGLSELNREAVAQARLVANPGCYPTCVSLP
                     LVPLLRQCRLKPGMPLIADCKSGVSGAGRKGNVGSLLCEVGDNFKAYGIAGHRHLPEI
                     RQTIAGLQDGIAEGFVFTPHLAPMIRGMHATVYLHLSDGICPETILRDYYRDSLFVDI
                     LPAGSTPETRSVRGANLCRISIQQAAQSDVWVVLSVIDNLVKGAAGQAVQNMNIMFGL
                     KETHGLGAIPLLP"
     gene            complement(1471..1752)
                     /locus_tag="ACFOV4_001721"
     CDS             complement(1471..1752)
                     /locus_tag="ACFOV4_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619686.1"
                     /translation="MKTLVLLLLSFSTTTAFAAYGLGLGQAPKYPAGFRAYGYVYSGR
                     QGWVLKTEADAIKLDTLFKRFVYRPSAANQNPVGQRSDGIPANHTKEKP"
     gene            2006..3160
                     /locus_tag="ACFOV4_001722"
     CDS             2006..3160
                     /locus_tag="ACFOV4_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFC7619687.1"
                     /translation="MSIHLDFGISPKTFRQTYLYQKPKLFKGAVRNLESASWKDINEI
                     YQRADPTAPLFHLRKKGAIVPKEEYVESFDDLGKTRYRFIKSVIYEHMKNGASLVYNH
                     INNEPFSDHIARQVARFAGAHTIVSGYLAFGSDESYKNHWDPRDVYAIQLFGKKRWQL
                     TAPDFPMPLYMQQTKDTDISIPEHIDMDIILEAGDVLYIPRGWWHRPIPLGCETFHFA
                     VGTFPPNGYNYLEWLMKKFPTIESLRHSFSDWEQDRTRINDTATQIAAMIADPVNYEA
                     FSEDFLGKERTDTAFHLEQFANPNATPLSDDVRLRLNANNLDTLEKGYLIGNGMKISV
                     DELGKKVLEHIGKNEPLLLKNLLVNFNQGKYEEVRKLIYQLIELDFLEIL"
     gene            3169..3396
                     /locus_tag="ACFOV4_001723"
     CDS             3169..3396
                     /locus_tag="ACFOV4_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619688.1"
                     /translation="MKNWKQFTFFVILVIACYQVLYFLSDMFLLDYINKYSWNLNFIQ
                     GTLNFFSIYLPYVFVSRIFRNTNQEKEYKND"
     gene            3389..3742
                     /locus_tag="ACFOV4_001724"
     CDS             3389..3742
                     /locus_tag="ACFOV4_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619689.1"
                     /translation="MIELQLHELKLVSGGGPVTDNIAGNVANAATTKGGPTWGDLVAI
                     PAAAAAVYYLPKNAYGAAGANGVYNVTRNWVNDAVNAPPYNGRPIFEIEHGLTAPATK
                     ADKSGNGYTDGTDYC"
     gene            3803..4429
                     /locus_tag="ACFOV4_001725"
     CDS             3803..4429
                     /locus_tag="ACFOV4_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HFC7619690.1"
                     /translation="MNRPKQPFFRPEVAVARQTSLTGKVILTRPLSFSLWTTFASISA
                     LLIILFLIFGNYTRKTTVEGQILPASGVIRVYAPDTGTITAKFVEDGEKVKAGDKLFA
                     LSTSRFGAGGSVQQQLKTEAVLKKTLAEQELGRLKLIHENETRSLKATVERLENQKLH
                     ILQQIDGQKRRIRLAEDQWQKRHWADRNCRDWAWYPPIWRRATNLFIS"
     gene            4333..4581
                     /locus_tag="ACFOV4_001726"
                     /pseudo
     CDS             4333..4581
                     /locus_tag="ACFOV4_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFP transporter"
     gene            5024..5326
                     /locus_tag="ACFOV4_001727"
     CDS             5024..5326
                     /locus_tag="ACFOV4_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619691.1"
                     /translation="MTWVGGSGNAQQSSYYCEICESAGLNDTGNPDKSLGLPNNTFSN
                     PPGWGATIGALAGSRIGMPEFGTFASHAIENFDWSWYRRYREIAETIEREYSGGLP"
     gene            5610..5762
                     /locus_tag="ACFOV4_001728"
                     /pseudo
     CDS             5610..5762
                     /locus_tag="ACFOV4_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009117473.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
     gene            5919..7661
                     /gene="hrpB"
                     /locus_tag="ACFOV4_001729"
     CDS             5919..7661
                     /gene="hrpB"
                     /locus_tag="ACFOV4_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-partner secretion system transporter HrpB"
                     /protein_id="HFC7619692.1"
                     /translation="MKFFPAPCLLVILAVIPLKTLAADENDAELIRSMQRQQHIDAEL
                     LTDANVRFEQPLEKNNYVLSEDETPCTRVNYISLDDKTARKFSFLPSVLMKETAFKTG
                     MCLGSNNLSRLQKAAQQILIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEK
                     RDGKSAEGSISAFNNKFPLYRNKILNLRDVEQGLENLRRLSSVKTDIQIIPSEEEGKS
                     DLQIKWQQNKPIRFSIGIDDAGGKTTGKYQGNVALSFDNPLGLSDLFYVSYGRGLAHK
                     TDLTDATGTETASGSRSYSVHYSVPVKKWLFSFNHNGHRYHEATEGYSVNYDYNGKQY
                     QSSLAAERMLWRNRFHKTSVGMKLWTRQTYKYIDDAEIEVQRRRSAGWEAELRHRAYL
                     NRWQLDGKLSYKRGTGMRQSMPAPEENGGGTIPGTSRMKIITAGLDAAAPFMLGKQQF
                     FYATAIQAQWNKTPLVAQDKLSIGSRYTVRGFDGEQSLFGERGFYWQNTLTWYFHPNH
                     QFYLGADYGRVSGESAQYVSGKQLMGAVVGFRGGHKVGGMFAYDLFAGKPLHKPKGFQ
                     TTNTVYGFNLNYSF"
     gene            7771..>12035
                     /gene="hrpA"
                     /locus_tag="ACFOV4_001730"
     CDS             7771..>12035
                     /gene="hrpA"
                     /locus_tag="ACFOV4_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-partner secretion exoprotein HrpA"
                     /protein_id="HFC7619693.1"
                     /translation="MNKGLHRIIFSKKHSTMVAVAETANSQGKGKQAGSSVSVSLKTS
                     GDLCGKLKTTLKTLVCSLVSLSMVLPAHAQITTDKSAPKNQQVVILKTNTGAPLVNIQ
                     TPNGRGLSHNRYTQFDVDAKGAVLNNDRNNNPFLAKGSAQLILNEVRGAASKLNGIVT
                     VGGQKADVIIANPNGITVNGGGFKNVGRGILTTGAPQIGKDGALTGFDVRQGTLTVGA
                     AGWNDKGGADYTEILARAVALQGKLQGKNLAVSTGAQKVDYASGEISAGTAAGTKPTI
                     ALDTAALGGMYADSITLIANEKGVGVKNAGTLEAAKQLIVTSSGRIENSGRIATTADG
                     TEASPTYLSIETTEKGAAGTFISNGGRIESKGLLVIETGEDISLRNGAVVQNNGSRPA
                     TTVLNAGHNLVIESKTNVNNAKGSANLSAGGRTTINDATIQAGSSVYSSTKGDTELGE
                     NTRIIAENVTVLSNGSIGSAAVIEAKDTAHIESGKPLSLETSTVASNIRLNNGNIKGG
                     KQLALLADDNITAKTTNLNTPGNLYVHTGKDLNLNVDKDLSAASIHLKSDNAAHITGT
                     SKTLTASKDMGVEAGLLNVTNTNLRTNSGNLHIQAAKGNIQLRNTKLNAAKALETTAL
                     QGNIVSDGLHAVSADGHVSLLANGNADFTGHNTLTAKADVNAGSVGKGRLKADNTNIT
                     SSSGDITLVAGNGIQLGDGKQRNSINGKHISIKNNGGNADLKNLNVHAKSGALNIHSD
                     RALSIENTKLESTHNTHLNAQHERVTLNQVDAYAHRHLSITGSQIWQNDKLPSANKLV
                     ANGVLALNARYSQIADNTTLRAGAINLTAGTALVKRGNINWSTVSTKTLEDNAELKPL
                     AGRLNIEAGSGTLTIEPANRISAHTDLSIKTGGKLLLSAKGGNAGAPSAQVSSLEAKG
                     NIRLVTGETDLRGSKITAGKNLVVATTKGKLNIEAVNNSFSNYFPTQKAAELNQKSKE
                     LEQQIAQLKKSSPKSKLIPTLQEERDRLAFYIQAINKEVKGKKPKGKEYLQAKLSAQN
                     IDLISAQGIEISGSDITASKKLNLHAAGVLPKAADSEAAAILIDGITDQYEIGKPTYK
                     SHYDKAALNKPSRLTGRTGVSIHAAAALDDARIIIGASEIKAPSGSIDIKAHSDIVLE
                     AGQNDAYTFLKTKGKSGKIIRKTKFTSTRDHLIMPAPVELTANGITLQAGGNIEANTT
                     RFNAPAGKVTLVAGEELQLLAEEGIHKHELDVQKSRRFIGIKVGKSNYSKNELNETKL
                     PVRVVAQTAATRSGWDTVLEGTEFKTTLAGADIQAGVGEKARVDAKIILKGIVNRIQS
                     EEKLETNSTVWQKQAGRGSTIETLKLPSFESPTPPKLSAPGGYIVDIPKGNLKTEIEK
                     LSKQPEYAYLKQLQVAKNINWNQVQLAYDRWDYKQEGLTEAGAA"
BASE COUNT         3449 a         2792 c         2887 g         2907 t
ORIGIN      
        1 gattttaaat tgcaggtatt taccgggaaa aacggcaagc cctccgccgt cattcccgcg
       61 caggcgggaa tctagaaatg aaaaaccacg gtgttatcgg caatgactga aaccggagaa
      121 atgacgaaat tgaagcgtgt ggaaatgtgt cggaaatcgc tgaagccgga taaactatag
      181 tggattaaat ttaaatcagg acaaggcgac gaagccgcag acagtacaga tagtacggca
      241 aggcgaggca acgctgtact ggtttaaatt taatccacta tagattcccg cttttgcggg
      301 aatgacggta ttttagattt ttgttttcgc ggaataatga gccaaaagcc gtccgaaccc
      361 aaaaaaaccg tcgctttcag acggcatcaa aaaaccgcag gcacgatgcc tgcggtttgc
      421 cgtttgcgct tcaggggagc agggggattg cgcccaagcc gtgtgtttcc ttcagtccga
      481 acatgatgtt catattttgc accgcctgac ccgccgcgcc tttgacgagg ttgtcgatga
      541 cggaaaggac gacccacaca tcggattgcg ccgcctgttg gatgctgatg cggcagaggt
      601 ttgcgccgcg cacgctgcgg gtttcgggtg tcgaaccggc gggcaggatg tccacgaaca
      661 ggctgtcgcg gtaatagtcg cgcaggatgg tttcggggca gatgccgtct gaaaggtgga
      721 ggtaaacggt ggcgtgcata ccgcgtatca tcggcgcgag gtgcggcgtg aacacgaatc
      781 cttcggcgat gccgtcctga agcccggcga tggtctgcct gatttcgggc aggtggcggt
      841 gtccagctat gccgtaggct ttgaagttgt cgccgacttc gcacaacagc gaaccgacat
      901 tgcctttcct gcccgcgccg gacacgccgg atttgcagtc ggcaatcagc ggcataccgg
      961 gcttcagacg gcattgccgc aacagcggca cgagcggcag ggatacgcag gtcgggtagc
     1021 agccggggtt ggcgacgagg cgcgcctgtg cgacggcttc gcggttgagt tcgctcaatc
     1081 cgtacacggc ttgggaaacg aggccggggg cggcgtgggt catgccgtac cagtgttccc
     1141 aggtcggaat gtcccatatg cggaagtcgg cggaaaggtc gatgacgcgc acgccctgtt
     1201 caatcaggcg cggcgcgtct ttcatggcga tgccgttggg cgtggcgaag aagacgatgt
     1261 cgcattgttc caaacctgcc tcgtcgggcg tttggaaggc gaggccgtac acgccgcgca
     1321 aactcggaaa gtaatcggca actgcggttc ccgcttcgct gcggctggtt acggcggcga
     1381 cttcgacatc gggatgggcg gcaagcaggc gcagcagttc cacgccggtg tagcccgtcg
     1441 cgccgacaat gccgactttg atttttttac tcatggtttt tcctttgtgt ggttggcggg
     1501 tatgccgtcc gaacgctgtc cgacggggtt ttgattggcg gcggaaggac ggtacacaaa
     1561 gcgtttgaaa agcgtgtcta atttaatggc atccgcctct gtttttaaaa cccagccctg
     1621 ccgtccggaa taaacataac cgtaggcgcg aaagccggca ggatatttcg gtgcctgccc
     1681 caaacccaaa ccgtatgcgg cgaaagcggt ggtcgtggag aaggaaagca ggaggaggac
     1741 gagggttttc ataaggttcc aaaccgaacg gggcgatgaa gcccgattat agcaaaaggt
     1801 cgtctgaaaa ccgttttcag acgacctttt atttaattac aataaaaatg ttaacaacaa
     1861 aaaacaaacc gcttttttcc gtttggagac aaatttttaa ctaaaattgt caacaattcc
     1921 ttgacgcaca cacaaaaaaa actttaatat ttgtaaatat atgtaacatt ataaatttta
     1981 aatattttct gagtaagggg aagtaatgag catccatctc gacttcggca ttagtcctaa
     2041 aacgttccga cagacttatc tgtatcaaaa gcccaagctc tttaaaggag cggttcggaa
     2101 tctcgaatcc gcatcttgga aagatatcaa cgagatatac caacgagcag acccaaccgc
     2161 accgctgttt catctgcgta aaaaaggcgc aatcgttcct aaagaagaat acgtcgaaag
     2221 tttcgacgat ttgggcaaaa ctcgctaccg ttttattaaa tccgttatct acgaacatat
     2281 gaagaatggt gcgtcgttag tctataacca tattaacaac gagccgtttt cagaccatat
     2341 cgcccgtcaa gtcgcccgct ttgccggcgc acatactatt gttagtggat atcttgcttt
     2401 tggcagcgac gaatcttata aaaaccattg ggacccccgc gatgtgtatg ccatccagct
     2461 tttcggcaag aaacgttggc aacttactgc ccctgatttc cctatgccat tgtatatgca
     2521 acagactaaa gatactgata tttccattcc tgaacatatc gatatggata ttatccttga
     2581 agcaggtgat gtcctctaca tcccacgcgg ttggtggcac agacctatcc cgctcggctg
     2641 tgaaaccttc cacttcgctg tcggtacctt cccaccaaac ggctataatt acctcgagtg
     2701 gctaatgaag aaatttccca ccatagaaag tctgcgccac agtttctcag actgggagca
     2761 agataggacg cgtatcaacg atactgccac acaaattgct gccatgattg ccgaccccgt
     2821 caattatgaa gccttcagtg aagactttct cggcaaagaa cgtaccgata ccgcttttca
     2881 tctcgaacag ttcgcgaatc ccaacgctac tccgctttca gacgacgtca ggttgagatt
     2941 aaatgccaat aatttggata cgttggaaaa gggatatttg attgggaatg ggatgaagat
     3001 aagcgtagat gagttgggga aaaaagtgtt agaacacatc ggtaagaatg aaccgttatt
     3061 gttgaaaaat ctactggtta acttcaatca gggaaaatat gaagaagtta ggaagttgat
     3121 ttatcagttg atagagttag attttctgga aattttgtga gggattctat gaaaaactgg
     3181 aagcaattta catttttcgt aatattagta atagcttgtt atcaagtgct atatttttta
     3241 tcagatatgt ttcttctcga ctacattaac aaatatagtt ggaatttgaa ttttattcag
     3301 ggtactttga attttttttc aatatatctg ccatatgttt ttgttagccg aatttttagg
     3361 aataccaacc aagaaaagga gtataaaaat gattgaactt caacttcatg aattgaagct
     3421 ggtttcaggg ggaggtcctg taacagacaa tatagctgga aatgtagcta atgctgccac
     3481 aaccaaagga ggtcccacat ggggggattt ggttgcaata cctgctgccg cagcggcagt
     3541 ttattatctg ccgaaaaatg cttacggtgc tgctggtgca aatggtgtat acaatgtgac
     3601 tcgtaattgg gtaaatgatg ccgttaatgc acctccttat aacggaagac caatctttga
     3661 gattgaacat ggattaactg ctcccgcaac aaaagcagat aaatcaggaa acggctacac
     3721 tgacggtaca gattactgct gatatttctc atcgtccaga caatctctag gggtcgtctg
     3781 aaactttctt aacttcaatt ttatgaatag acccaagcaa cccttcttcc gtcccgaagt
     3841 cgccgttgcc cgccaaacca gcctgacggg taaagtgatt ctgacacgac cgttgtcatt
     3901 ttccctatgg acgacatttg catcgatatc tgcgttattg attatcctgt ttttgatatt
     3961 tggtaactat acgcgaaaga caacagtgga gggacaaatt ttacctgcat cgggcgtaat
     4021 cagggtgtat gcaccggata cggggacaat tacagcgaaa ttcgtggaag atggagaaaa
     4081 ggttaaggct ggcgacaagc tatttgcgct ttcgacctca cgtttcggcg caggaggtag
     4141 cgtgcagcag cagttgaaaa cggaggcagt tttgaagaaa acgttggcag aacaggaact
     4201 gggtcgtctg aagctgatac acgagaatga aacgcgcagc cttaaagcaa ctgtcgaacg
     4261 tttggaaaac cagaaactcc atattttgca acagatagac ggtcagaaaa ggcgcattag
     4321 acttgcggaa gatcagtggc aaaaacggca ctgggcagac aggaattgtc gggattgggc
     4381 atggtatcct ccgatttggc gaagagcaac gaacctgttt atctcgtgaa aataaaaccc
     4441 gacaaaccaa ccatcactgc atacggtgag gaaaaaccgc tgcaaatcgg catgacgttg
     4501 gaagcagaca tcctacacga gaaacggcga ttgtacgaat gggtattgga gctgatttat
     4561 agtatgtcgg gcaaactgta agacttgagg ctgtaaagat aaagaagttg tctgaaacct
     4621 tttcagacga ccagaagaca atatgagacc tttgcaataa cataggttac taaaatttta
     4681 tgctcaatct cattttcaaa atgcaaaact tttctgattt ttcctacttt ttgctcaata
     4741 ttaggaaggt tttaggcaat tgaaaatttt ttggcgcatt tttatgcgtc aaatttcgtt
     4801 aacagactat ttttgcaaag gtctccgttt gtaaaagcaa ggatagggca tctgcccttt
     4861 tgattgtttg attaacgata caaggagttt caaaatgaga gttttatagt ggattaaatt
     4921 taaaccagta cagcgttgcc tcgccttgcc gtaccatttg tactgtctgc ggcttcgtcg
     4981 ccttgtcctg atttaaattt aatccactat atgtgttcat gaaatgactt gggtcggagg
     5041 ctcaggtaat gcgcaacaaa gttcatatta ttgcgaaatt tgcgaatctg cagggcttaa
     5101 cgatacggga aatcctgata aatctttagg attgccaaac aatacgttca gtaatccgcc
     5161 tggttgggga gctacaatcg gagctttagc aggtagccgc atagggatgc ctgaatttgg
     5221 tacgtttgcg agccatgcca ttgaaaattt cgactggtca tggtatcgac gttataggga
     5281 aattgccgaa acgattgaac gagaatattc aggcggtttg ccttaatagt tgaggaggtc
     5341 atgatgtttg ccaaacatta tcaattcatc gcactcggca tcatgctgct tctttatatg
     5401 ttgattctct atacgaccga tttttccaat ctgacgtatt ggatgctgtt ttttatctgt
     5461 tttattacag gaaaaatatt agctcgtttg ttagagaaaa gctttaaata aaatagcagc
     5521 tagtcgcaaa aggtcgtctg aaaccttttc aggcggcctt tctaaaatac atccaacttc
     5581 ctaatcccta tttttcaaaa aggaaatcta tgccccatct gcaaaacctg tctttgggct
     5641 taaagaaaaa gctgcctgtt atcctgcaaa cagaaatatc agaatgcggc ttggcatgtc
     5701 tggcggctgt ggcgggattt catggtttcc atacggattt acgcgcactg cgttcaaaat
     5761 actgtccgag acctttgcaa aattccccaa aatcccctaa atgtcttggt gggaattttg
     5821 gggattttgg ggaattttgc aaaggtctca ttctataact gtaaatactt ttaaatttat
     5881 gacagaatag taaatattgc taaaataata ttaatgtcat gaaatttttt cctgctccat
     5941 gtctgttggt tatcctggct gtcatacccc ttaaaacctt agctgccgat gaaaacgatg
     6001 cagaacttat ccgttccatg cagcgtcagc agcacataga tgctgaattg ttaactgatg
     6061 caaatgtccg tttcgagcaa ccattggaga agaacaatta tgtcctgagt gaagatgaaa
     6121 caccgtgtac tcgggtaaat tacattagtt tagatgataa gacggcgcgc aaattttctt
     6181 ttcttccttc tgtgctcatg aaagaaacag cttttaaaac tgggatgtgt ttaggttcca
     6241 ataatttgag caggctacaa aaagccgcgc aacagatact gattgtgcgt ggctacctca
     6301 cttcccaagc tattatccaa ccacagaata tggattcggg aattctgaaa ttacgggtat
     6361 cagcaggcga aataggggat atccgctatg aagaaaaacg ggatgggaag tctgccgagg
     6421 gcagtattag tgcattcaat aacaaatttc ccttatatag gaacaaaatt ctcaatcttc
     6481 gcgatgtaga gcagggcttg gaaaacctgc gtcgtttgtc gagtgttaaa acagatattc
     6541 agattatacc gtccgaagaa gaaggcaaaa gcgatttaca gatcaaatgg cagcagaata
     6601 aacccatacg gttcagtatc ggtatagatg atgcgggcgg caaaacgacc ggcaaatatc
     6661 aaggaaatgt cgctttatcg ttcgataacc ctttgggctt aagcgatttg ttttatgttt
     6721 catatggacg cggtttggcg cacaaaacgg acttgactga tgccaccggt acggaaactg
     6781 caagcggatc cagaagttac agcgtgcatt attcggtgcc cgtaaaaaaa tggctgtttt
     6841 cttttaatca caatggacat cgttaccacg aagcaaccga aggctattcc gtcaattacg
     6901 attacaacgg caaacaatat cagagcagcc tggccgccga gcgcatgctt tggcgtaaca
     6961 ggtttcataa aacttcagtc ggaatgaaat tatggacacg ccaaacctat aaatacatcg
     7021 acgatgccga aatcgaagtg caacgccgcc gctctgcagg ctgggaagcc gaattgcgcc
     7081 accgtgctta cctcaaccgt tggcagcttg acggcaagtt gtcttacaaa cgcgggaccg
     7141 gcatgcgcca aagtatgccc gcacctgaag aaaacggcgg cggtactatt ccaggcacat
     7201 cccgtatgaa aatcataacc gccggattgg atgcagcggc cccgtttatg ttgggcaaac
     7261 agcagttttt ctacgcaacc gccattcaag ctcaatggaa caaaacgcct ttggttgccc
     7321 aagacaagtt gtctatcggc agccgctaca ccgttcgcgg atttgatggg gagcagagtc
     7381 ttttcggaga gcgaggtttc tactggcaga atactttaac ttggtatttt catccgaacc
     7441 atcagttcta tctcggtgcg gactatggcc gcgtatctgg cgaaagtgca caatatgtat
     7501 cgggcaagca gctgatgggt gcagtggtcg gcttcagagg agggcataaa gtaggcggta
     7561 tgtttgctta tgatctgttt gccggcaagc cgcttcataa acccaaaggc tttcagacga
     7621 ccaacaccgt ttacggcttc aacttgaatt acagtttcta acctctgaat ttttttactg
     7681 atatttagac ggtctttcct tatcctcaga ctgtcaaact ttacctacgt acttggcgcg
     7741 cagtacgttc atcttcaaaa tggaatagac atgaataaag gtttacatcg cattatcttt
     7801 agtaaaaagc acagcaccat ggttgcagta gccgaaactg ccaacagcca gggcaaaggt
     7861 aaacaggcag gcagttcggt ttctgtttca ctgaaaactt caggcgacct ttgcggcaaa
     7921 ctcaaaacca cccttaaaac cttggtctgc tctttggttt ccctgagtat ggtattgcct
     7981 gcccatgccc aaatcaccac cgacaaatca gcacctaaaa accagcaggt cgttatcctt
     8041 aaaaccaaca ctggtgcccc cttggtgaat atccaaactc cgaatggacg cggattgagc
     8101 cacaaccgct atacccagtt tgatgtcgac gctaaaggtg ctgtactgaa caacgatcgc
     8161 aacaacaacc cgtttctggc caaaggcagt gcgcagttga ttttgaacga ggtgcgcggt
     8221 gcggccagca aactcaatgg catcgttacc gtaggtggtc aaaaggccga tgtgattatt
     8281 gccaacccca acggcattac cgttaatggc ggcggcttta aaaatgtcgg tcggggcatc
     8341 ttaactaccg gtgcgcccca aatcggcaaa gacggtgcac tgacaggatt tgatgtgcgt
     8401 caaggcacat tgaccgtagg agcagcaggt tggaatgata aaggcggagc cgactacacc
     8461 gagatacttg ctcgtgcagt tgctttgcag gggaaattac agggtaaaaa cctggcggtt
     8521 tcgaccggcg cacagaaagt agattacgcc agcggcgaaa tcagtgcagg tacggcagcg
     8581 ggtacgaaac cgactattgc ccttgatact gccgcactgg gcggtatgta cgcagacagc
     8641 atcacactga ttgccaatga aaaaggcgta ggcgtcaaaa atgccggcac actcgaagcg
     8701 gccaagcaat tgattgtgac ttcgtcaggc cgcattgaaa acagcggccg catcgccacc
     8761 actgccgacg gcaccgaagc ttcaccgact tatctctcca tcgaaaccac cgaaaaagga
     8821 gcggcaggca catttatctc caatggtggt cggatcgaga gcaaaggctt attggttatt
     8881 gagacgggag aagatatcag cttgcgtaac ggagccgtgg tgcagaataa cggcagtcgc
     8941 ccagctacca cggtattaaa tgctggtcat aatttggtga ttgagagtaa aactaatgtg
     9001 aacaatgcca aaggctcggc taatctgtcg gccggcggtc gtactacgat caatgatgct
     9061 actattcaag cgggcagttc cgtgtacagc tccaccaaag gcgatactga attgggtgaa
     9121 aatacccgta ttattgctga aaacgtaacc gtattatcta acggtagtat tggcagtgct
     9181 gctgtaattg aggctaaaga cactgcacac attgaatcgg gcaaaccgct ttctttagaa
     9241 acctcgaccg ttgcctccaa catccgtttg aacaacggta acattaaagg cggaaagcag
     9301 cttgctttac tggcagacga taacattact gccaaaacta ccaatctgaa tactcccggc
     9361 aatctgtatg ttcatacagg taaagatctg aatttgaatg ttgataaaga tttgtctgcc
     9421 gccagcatcc atttgaaatc ggataacgct gcccatatta ccggcaccag taaaaccctc
     9481 actgcctcaa aagacatggg tgtggaggca ggcttgctga atgttaccaa taccaatctg
     9541 cgtaccaact cgggtaatct gcacattcag gcagccaaag gcaatattca gcttcgcaat
     9601 accaagctga acgcagccaa ggctctcgaa accaccgcat tgcagggcaa tatcgtttca
     9661 gacggccttc atgctgtttc tgcagacggt catgtatcct tattggccaa cggtaatgcc
     9721 gactttaccg gtcacaatac cctgacagcc aaggccgatg tcaatgcagg atcggttggt
     9781 aaaggccgtc tgaaagcaga caataccaat atcacttcat cttcaggaga tattacgttg
     9841 gttgccggca acggtattca gcttggtgac ggaaaacaac gcaattcaat caacggaaaa
     9901 cacatcagca tcaaaaacaa cggtggtaat gccgacttaa aaaaccttaa cgtccatgcc
     9961 aaaagcgggg cattgaacat tcattccgac cgggcattga gcatagaaaa taccaagctg
    10021 gagtctaccc ataatacgca tcttaatgca caacacgagc gggtaacgct caaccaagta
    10081 gatgcctacg cacaccgtca tctaagcatt accggcagcc agatttggca aaacgacaaa
    10141 ctgccttctg ccaacaagct ggtggctaac ggtgtattgg cactcaatgc gcgctattcc
    10201 caaattgccg acaacaccac gctgagagcg ggtgcaatca accttactgc cggtaccgcc
    10261 ctagtcaagc gcggcaacat caattggagt accgtttcga ccaagacttt ggaagataat
    10321 gccgaattaa aaccattggc cggacggctg aatattgaag caggtagcgg cacattaacc
    10381 atcgaacctg ccaaccgcat cagtgcgcat accgacctga gcatcaaaac aggcggaaaa
    10441 ttgctgttgt ctgcaaaagg aggaaatgca ggtgcgccta gtgctcaagt ttcctcattg
    10501 gaagcaaaag gcaatatccg tctggttaca ggagaaacag atttaagagg ttctaaaatt
    10561 acagccggta aaaacttggt tgtcgccacc accaaaggca agttgaatat cgaagccgta
    10621 aacaactcat tcagcaatta ttttcctaca caaaaagcgg ctgaactcaa ccaaaaatcc
    10681 aaagaattgg aacagcagat tgcgcagttg aaaaaaagct cgcctaaaag caagctgatt
    10741 ccaaccctgc aagaagaacg cgaccgtctc gctttctata ttcaagccat caacaaggaa
    10801 gttaaaggta aaaaacccaa aggcaaagaa tacctgcaag ccaagctttc tgcacaaaat
    10861 attgacttga tttccgcaca aggcatcgaa atcagcggtt ccgatattac cgcttccaaa
    10921 aaactgaacc ttcacgccgc aggcgtattg ccaaaggcag cagattcaga ggcggctgct
    10981 attctgattg acggcataac cgaccaatat gaaattggca agcccaccta caagagtcac
    11041 tacgacaaag ctgctctgaa caagccttca cgtttgaccg gacgtacggg ggtaagtatt
    11101 catgcagctg cggcactcga tgatgcacgt attattatcg gtgcatccga aatcaaagct
    11161 ccctcaggca gcatagacat caaagcccat agtgatattg tactggaggc tggacaaaac
    11221 gatgcctata ccttcttaaa aaccaaaggt aaaagcggca aaatcatcag aaaaaccaag
    11281 tttaccagca cccgcgacca cctgattatg ccagcccccg tcgagctgac cgccaacggt
    11341 atcacgcttc aggcaggcgg caacatcgaa gctaatacca cccgcttcaa tgcccctgca
    11401 ggtaaagtta ccctggttgc gggtgaagag ctgcaactgc tggcagaaga aggcatccac
    11461 aagcacgagt tggatgtcca aaaaagccgc cgctttatcg gcatcaaggt aggtaagagc
    11521 aattacagta aaaacgaact gaacgaaacc aaattgcctg tccgcgtcgt cgcccaaact
    11581 gcagccaccc gttcaggctg ggataccgtg ctcgaaggta ccgaattcaa aaccacgctg
    11641 gccggtgccg acattcaggc aggtgtaggc gaaaaagccc gtgtcgatgc gaaaattatc
    11701 ctcaaaggca ttgtgaaccg tatccagtcg gaagaaaaat tagaaaccaa ctcaaccgta
    11761 tggcagaaac aggccggacg cggcagcact atcgaaacgc taaaactgcc cagcttcgaa
    11821 agccctactc cgcccaaatt gtccgcaccc ggcggctata tcgtcgacat tccgaaaggc
    11881 aatctgaaaa ccgaaatcga aaagctgtcc aaacagcccg agtatgccta tctgaaacag
    11941 ctccaagtag cgaaaaacat caactggaat caggtgcagc ttgcttacga cagatgggac
    12001 tacaaacagg agggcttaac cgaagcaggt gcggc
//
LOCUS       DAXISH010000062        11823 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.062, whole genome shotgun sequence.
ACCESSION   DAXISH010000062 DAXISH010000000
VERSION     DAXISH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 11823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11823
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.062"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            100..816
                     /locus_tag="ACFOV4_001731"
     CDS             100..816
                     /locus_tag="ACFOV4_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFC7619694.1"
                     /translation="MNFENDDIIHAPTTSSLILEERHDSELFRVYALILDGITDQVLL
                     PGKKLTESELCRQMVCSRNTVRGALSLLAHDKIVDLQPNRGAFVHVPDLKEMQDVFNA
                     RIEMETMILNILADLPDLETRLKPLYAMIRREEEASGRGDRVGWNRLSNAFHVELARL
                     VGNDVLFDIMNTLCARSSLIVAVAGVHREEKHAINTHTHSEHREILDLLLAGRRNRVV
                     KILRRHLGNCMERLEKTLED"
     gene            965..1867
                     /locus_tag="ACFOV4_001732"
     CDS             965..1867
                     /locus_tag="ACFOV4_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine exporter LysO family protein"
                     /protein_id="HFC7619695.1"
                     /translation="MDSLMTLLSVLIPMFAGFFIRVPKPYLPALDKVLSVLVYAVLLL
                     IGVSLSRVEDLGSRLDDMALTVLWLFVCTVGANLLALAVLGKLFPWRIKGKGKGVSVG
                     VSGSVGQLGCVLLGFAFGKLMRDIWMPSESAGMYCLMLLVFLIGVQLKSSGVSLRQVL
                     VNRRGIRLSVWFMLSSLSGGLLFAASTDGVSWTKGLAMASGFGWYSLSGLVMTEAYGA
                     VWGSIMLLNDLARELFALAFIPLLMKRFPDAAVGVGGATSMDFTLPVIQGAGGLEVVP
                     VAVSFGVVVNIAAPFLMVVFSALG"
     gene            1910..2683
                     /locus_tag="ACFOV4_001733"
     CDS             1910..2683
                     /locus_tag="ACFOV4_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFC7619696.1"
                     /translation="MKPKIQRHGEILSLVRRHQFMSVDELAAALDVTPQTIRRDIREL
                     EEGGSLKRHHGGASSGGNLPEGLPADRQTRCQNEKNAIARLIAEHIPDGSSLFVSIGT
                     TMEAVASELVRRRGSLRIITNNIHVASIVSARTDYTVIITSGVVRPLDGGITGVATVD
                     FINQFKVDYAVMSTHGVESDGSLLDDDYKEVSVMQAMIANARVRFLGVDHSKFRSNAL
                     VRLGDITAFDKVFTDRLPDTAMQKMLKEAGVECLIADAV"
     gene            2795..4483
                     /locus_tag="ACFOV4_001734"
     CDS             2795..4483
                     /locus_tag="ACFOV4_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HFC7619697.1"
                     /translation="MLNKDQFADNHFIRTIIEDDLKSGKHEAVQTRFPPEPNGYLHIG
                     HAKSICLNFGLAYIYDGLCNLRFDDTNPEKENDEYVNAIKEDVEWLGFHWAGEPRFAS
                     NYFDQLYDYAVGLIKDGKAYVDDLTPEEMREYRGTLTEAGKNSPYRDRSVEENLDLFT
                     RMKNGEFPDGSKTLRLKIDMASGNINMRDPVIYRIRRAHHHNTGDKWCIYPMYDYTHC
                     ISDAIEGITHSLCTLEFEAHRPLYDWVLDNIHAPHATRPRQYEFSRLELLYTITSKRK
                     LNQLVVEKHVSGWDDPRMPTISGMRRRGYTPEGLRLFAKRAGISKSENIVDMSVLEGA
                     IREELENSAPRLMAVLNPLKVTLTNFEAGRTQSRRAAFHPNHEEMGEREVPISQTIYI
                     EADDFAENPPKGFKRLIPGGEVRLRHGYVIKCDEVVKDEAGNVVELKCSIDHDTLGKN
                     PEGRKVKGVIHWVSAEHAAEIKVRLYDRLFTIERPDAVRGEDGEYLPFTDFLNPESVK
                     EITAYAEPAAKDLPAESRWQFERIGYFVTDRKDHGKDTPVFNRTVTLKDSWQPK"
     gene            4576..5532
                     /gene="gshB"
                     /locus_tag="ACFOV4_001735"
     CDS             4576..5532
                     /gene="gshB"
                     /locus_tag="ACFOV4_001735"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004363 - glutathione synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HFC7619698.1"
                     /translation="MKVLFIADPMASFKTYKDTTYAMMREMAKRGWRLFHTLSGELSV
                     KNGLVVADASAFEFLGAQDDHDKNWFAAADKVQTALKAFDAVIMRTDPPFDMQYLYAT
                     QLLTLAEQQGAKVFNSGQSMRDFNEKLAILNFSRFTAPTLVTTRSADVRAFLKEHGDI
                     IIKPLDGMGGMGIFRLTEKDPNIGSILETLMRLDSRTIMAQRYIPEIVHGDKRILIIG
                     GEVVPYALARIPQNGETRGNLAAGGRGVAQELGGRDREIAETLAPELKRRGILLAGLD
                     VIGSNLTEVNVTSPTGFQEIMKQKGFDVAAMFADAVAAWSVR"
     gene            5844..6227
                     /locus_tag="ACFOV4_001736"
     CDS             5844..6227
                     /locus_tag="ACFOV4_001736"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004143 - ATP-dependent diacylglycerol
                     kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFC7619699.1"
                     /translation="MEPSSYAAEKKGKGGIRRVINAFGYSIDGIAAAYRYEAAFRQVL
                     WLNVLLVCAAFFWVSETAVRLPLIIASFVSVIVELFNTAVEAAVDHTSTEKHELAKRA
                     KDAGSAAQLFAMLMLAAVWLSALFG"
     gene            6520..6993
                     /locus_tag="ACFOV4_001737"
     CDS             6520..6993
                     /locus_tag="ACFOV4_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016531 - copper chaperone activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone PCu(A)C"
                     /protein_id="HFC7619700.1"
                     /translation="MKKLLAAVMMAGLAGAVSAAGVHVEDGWARTTVEGMKIGGAFMK
                     IHNDEAKQDFLLGGSSPVADRVEVHTHINDNGVMRMREVEGGVPLEAKSVTELKPGSY
                     HVMFMGLKKQLKEGDKIPVTLKFKNAKAQTVQLEVKIAPMPAMNHGHHHGEAHQH"
     gene            7119..8222
                     /gene="mnmA"
                     /locus_tag="ACFOV4_001738"
     CDS             7119..8222
                     /gene="mnmA"
                     /locus_tag="ACFOV4_001738"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFC7619701.1"
                     /translation="MNTTANTTNIIVGLSGGVDSSVTAALLKQQGYQVRGVFMQNWED
                     DDNDEYCSIKQDSFDAIAVADIIGIDIDIVNFAAQYKDKVFAYFLQEYSAGRTPNPDV
                     LCNAEIKFKCFLDYAVGQGADTIATGHYARKEVRNGVHYLLKGLDRNKDQSYFLYRLK
                     PFQLERAIFPLGGLEKPEVRRLAAEFNLPTAAKKDSTGICFIGERPFREFLQKYLPTD
                     NGKMVTPEGKTVGEHVGLMFYTLGQRKGLGIGGAGEPWFVAAKDLTKNELIVVQGHDH
                     PLLYTRSLVMNDLSFTLPERPKAGRYTCKTRYRMADAPCELRYLDDETAELVFDEPQW
                     AVTPGQSAVLYDGDICLGGGIIQTTDKPVIITR"
     gene            8293..9963
                     /locus_tag="ACFOV4_001739"
     CDS             8293..9963
                     /locus_tag="ACFOV4_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFC7619702.1"
                     /translation="MKKIWLDSYEKGVSAEIDITQYNSVSDVFRQSVEKFADQPAFQN
                     MGKTLTYAETGKLATDFASYLQNVLKLPRGERVAIMLPNVLQYPIALFGILQAGLVAV
                     NTNPLYTPRELEHQLKDSGATAIIVLENFANTLELVLPRTQIKHVIVASVGEMFGLLK
                     GSLINFIIRKIKKMVPEYRIRETVSFQTALKEGAKHVFQPVALNREDTALLQYTGGTT
                     GVAKGAVLSHGNICANMLQAKEWIKNQLREGKETVIAALPLYHIFALTVNLMIFANAG
                     SKIILITNPRDMKGFIGQLKKQRVNVFIGVNTLFNAMVNRPDFAEVDFSGLRLTLGGG
                     MATQKAVAEKWKKITDTPIVEAYGLTEASPGVCCNPLNIESYSGSIGLPVSSTEVELR
                     DANGKEVPVGQPGELWVKGPQVMQGYWNRPEETAKAIDARGFLETGDIAVMDEKGWLK
                     LVDRKKDLIVVSGFNVYPNEIEEVIAHHGKVMEVACIGVPDEKTGEALKVFVVRKDPS
                     LTKEELIAFCRTELTAYKVPKDIEFRDELPKSNVGKILRRELRQSTGK"
     gene            10075..11709
                     /locus_tag="ACFOV4_001740"
     CDS             10075..11709
                     /locus_tag="ACFOV4_001740"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFC7619703.1"
                     /translation="MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLNVTMLKLDPYI
                     NVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFIDSTMTRRNSFSTGQVYENVIAKE
                     RRGDYLGGTVQVIPHITDEIKRRIHEGAAGYDVAIVEIGGTVGDIESLPFLEAIRQMR
                     SQLGRNNTLFAHLSYVPYIAAAGEIKTKPTQHTVKEMLSIGLQPDILICRMDREMPAD
                     ERRKIALFCNVEERAIVGSYDVDSIYECPEMLHDQGIDNIITEQLQLNVQQADLTAWK
                     KIVHAVKNPKHTVKIAMVGKYVDLTESYKSLIEALKHAGIHTETDVQITFVDSESIEK
                     NNGDVSMLKDMDAILVPGGFGSRGVEGKIAAVRYARENNVPYLGICLGMQIALIEYAR
                     DVAGLKGANSTEFDLKCAAPVVALIDEWQTADGSVETRDESADLGGTMRLGAQEVELK
                     TGSLAAKIYGSGHIRERHRHRYEVNNNYVPTLEQAGLVIGGVSAGRERLVETIELPNH
                     PWFFACQFHPEFTSNPRKGHPLFTAFVKAALNNKKA"
BASE COUNT         2932 a         3184 c         3127 g         2580 t
ORIGIN      
        1 taaatttgtg taatactttg atttccccga cacgatttga agcacagccg ccttaaaaca
       61 tcttaaaaaa tttgaaagcg taaaaatacg gaaaacatca tgaactttga aaacgacgac
      121 attatccatg cgccgaccac gtcttccctg attctcgaag agcggcacga ttcggagctg
      181 ttccgtgttt acgccctgat tttggacggc attaccgatc aggtgctgct gcccggcaaa
      241 aagctgaccg aatccgaact ttgccgtcag atggtgtgtt cgcgcaacac cgtccgcggc
      301 gcgctgtcgc ttttggcgca cgacaagatt gtcgatttgc aacccaacag gggcgcgttc
      361 gtccacgttc ccgatttgaa agaaatgcag gatgtgttca atgcgcgcat cgaaatggag
      421 acgatgattt tgaatatcct cgcagatttg ccggatttgg aaacgcgcct caagccgctt
      481 tatgcgatga tacggcgcga agaagaggcc tccggcaggg gcgaccgcgt tggctggaac
      541 cgcctgtcca atgccttcca cgtcgaactg gcgcgcctgg tgggcaacga tgtgctgttc
      601 gacattatga acacgctgtg cgcgcggtct tccctgattg tcgccgtggc gggcgtgcat
      661 cgcgaggaaa aacacgccat caatacgcat acgcattcag aacaccgcga aatcctcgac
      721 ctgctgctgg cgggcaggcg caaccgcgtg gtcaaaatcc tgcgccgcca tttgggcaac
      781 tgtatggagc gtttggaaaa gactttggaa gattgaatgc cggagcggat aagccgcctg
      841 aaccttcagg cggtttttta atggcgaacc tgatgccgtc tgaaatatgg atgcgggtat
      901 ctgcaatttt cagacggcaa tttttaaacc gcacatatca tgcggcaata aaggagagca
      961 gtagatggac agcctgatga cattgctttc ggtattgata ccgatgtttg ccggattttt
     1021 tatccgtgtg cccaagcctt acctgcccgc tttggataag gtgctatcgg tcttggtgta
     1081 tgctgtgctg ctgctgatcg gcgtctcgtt gtcgcgcgtg gaggatttgg gttcgcggtt
     1141 ggacgatatg gcgttgacgg ttctgtggct gtttgtttgt acggtcgggg cgaacctgct
     1201 tgctttggca gtgttgggaa agttattccc gtggcggata aaggggaaag ggaagggcgt
     1261 ttcggtcggc gtgtcgggca gtgtggggca gctcggatgc gtgctgctcg gatttgcatt
     1321 cggcaaactg atgcgcgata tttggatgcc gtctgaaagc gcgggcatgt attgtctgat
     1381 gctgctggtg ttcctcatcg gcgtacagct caaaagcagc ggcgtatcgt tgcggcaggt
     1441 tttggtcaac cgcaggggta ttcggttgtc ggtctggttt atgctttcat ctctttcggg
     1501 cgggctgctg tttgccgcat cgacagacgg tgtgtcgtgg acgaaaggtt tggcgatggc
     1561 ttccggcttc ggttggtatt ccctctcggg tttggtcatg accgaggctt acggcgcggt
     1621 atggggcagc atcatgctgc tgaacgattt ggcacgagag ctgtttgcac tggcatttat
     1681 cccgctgctg atgaagcgtt ttccggatgc ggcggtgggg gttggtggtg cgaccagtat
     1741 ggatttcaca ttgcccgtga ttcagggtgc gggcggtttg gaagtcgtgc cggtagcggt
     1801 cagcttcggc gtggtggtca atatcgccgc cccatttctg atggtggtgt tttccgcttt
     1861 gggttgaacg cggtaaaatc ggcatcccga tgcaaggagg cagaaaacga tgaaaccgaa
     1921 aatccaaagg cacggagaga ttttaagcct tgtccgccgg catcagttta tgtcggtgga
     1981 cgagcttgcc gccgcattgg acgttacccc gcagacgata cgccgcgaca tccgcgagtt
     2041 ggaggagggc ggcagcctga aacgccatca cggcggcgca tcttcgggcg gaaacttgcc
     2101 ggagggcctg cccgccgacc gccaaacccg gtgtcaaaac gaaaaaaacg ccattgcccg
     2161 gctgattgcg gaacacatcc ccgacggttc gtcgctgttt gtcagtatcg gcacgacgat
     2221 ggaagccgtg gcatcggagc tggtcaggcg gcgcggcagc ctgcggatta ttaccaacaa
     2281 tatccacgtc gcctccatcg tttcggcgcg gacggattac acggtcatta tcacttccgg
     2341 agtcgtccgc cctttggacg gcggtattac cggcgtggca accgtcgatt ttatcaacca
     2401 gttcaaagtc gattatgccg tgatgagtac gcacggcgtg gaaagcgacg gttcgctttt
     2461 ggacgacgac tacaaagaag tcagcgtgat gcaggcgatg attgccaatg cgcgcgtccg
     2521 cttcctcggc gtggaccaca gtaaattccg cagcaacgcg ctggtcaggc tcggcgacat
     2581 tacggcgttt gacaaagtat ttaccgaccg gctgcccgat accgcgatgc agaagatgct
     2641 gaaagaggcg ggggtggaat gcctgattgc cgatgccgtc tgaacgctat gtcaaagcgc
     2701 gcaagtcggg tacaataaac acatcatcaa accgcttcag acggcataag gaaccgcccc
     2761 aatgccgtct gaagccatct gttcaaagaa aactatgctc aataaagacc aatttgcgga
     2821 caaccatttt atccgcacca tcatcgaaga cgacctcaaa agcggcaaac acgaagccgt
     2881 ccaaacccgt tttccgccgg agcccaacgg ctacctgcac atcggacacg ccaaatccat
     2941 ctgcctgaac ttcggtttgg cgtatattta cgacggcttg tgcaacctgc gttttgacga
     3001 taccaacccc gaaaaagaaa acgacgaata cgtcaacgcc atcaaagaag atgtcgagtg
     3061 gctcggtttc cattgggcgg gcgagccgcg tttcgcttcc aactatttcg accagcttta
     3121 tgactacgcc gtcggtttga ttaaagacgg caaagcgtat gtcgatgatt tgacgcccga
     3181 agaaatgcgc gaataccgcg gtacgctgac cgaagcgggt aaaaacagcc cttaccgcga
     3241 ccgcagcgtc gaagaaaacc tcgacctgtt cacacgcatg aaaaacggcg agttccccga
     3301 cggcagcaaa accctgcgcc tgaaaatcga catggcatcg ggcaacatca atatgcgcga
     3361 ccccgtcatc taccgcatcc gccgcgccca tcaccacaac accggcgaca aatggtgtat
     3421 ctacccgatg tacgactaca cgcattgcat ctccgatgcc atcgaaggca tcacgcattc
     3481 cttgtgtacg ctcgaatttg aagcacaccg tccgctgtac gactgggtgt tggataacat
     3541 ccacgcgccg catgccaccc gtccgcgcca atacgagttt tcccgtttgg agcttttgta
     3601 caccattacc tccaaacgga aattgaatca gttggttgtg gaaaaacacg tttccggctg
     3661 ggacgatccg cgtatgccga ctatttccgg tatgcgccga cgcggctaca cgcccgaagg
     3721 cctgcgtctg tttgccaaac gcgccggtat ttccaaatct gaaaacatcg tcgatatgag
     3781 cgtgttggaa ggcgcgattc gcgaagagtt ggaaaattcc gccccacgcc tgatggcggt
     3841 gttgaacccg ctcaaagtga ccctgaccaa ctttgaagcc ggcagaaccc aaagccgccg
     3901 tgccgcgttc catccgaacc acgaggaaat gggcgagcgc gaagtaccta tttcacaaac
     3961 catctatatt gaagccgacg actttgccga aaatccgccc aaaggcttca aacgcctgat
     4021 tcccggcggc gaagtacgct tgcgccacgg ctatgtcatc aagtgcgatg aagtcgtcaa
     4081 agacgaagca ggcaatgtgg ttgaactcaa atgcagcatc gaccacgaca ccttgggcaa
     4141 aaatccagaa ggccgtaaag ttaaaggcgt gattcattgg gtttccgccg aacacgccgc
     4201 cgaaatcaaa gtccgtctgt acgaccgcct ctttaccatc gagcgtcccg atgccgtgcg
     4261 cggcgaagac ggcgaatacc tgccgttcac cgatttcctc aatccggaat ccgtcaagga
     4321 aatcaccgcc tacgccgaac ctgccgccaa agatttgccg gcagaaagcc gttggcagtt
     4381 cgagcgtatc ggctacttcg taaccgaccg taaagaccac ggcaaagaca cgccggtgtt
     4441 taaccgcacg gtcacgctga aagattcttg gcagcctaag taaaacccca tccttgccgt
     4501 ctgaatattg ttcggacggc atttcccctt tgcccgcgaa atgcggcaca ttcggcacac
     4561 cggaaaggaa atatgatgaa agtcctcttt atcgccgacc cgatggcaag tttcaaaacc
     4621 tacaaagaca ccacctacgc catgatgcgc gagatggcaa aacgcggttg gcggctgttt
     4681 cataccttga gcggggaatt gtcggttaaa aacggtctgg tggttgctga tgcgtctgct
     4741 tttgagtttc tcggcgcaca agacgaccac gacaaaaact ggtttgccgc cgccgacaaa
     4801 gttcagacgg cattgaaagc atttgatgcc gtgattatgc gtaccgatcc gccgttcgat
     4861 atgcaatacc tctacgccac ccaattactg acgctggcgg aacagcaggg cgcgaaagtc
     4921 tttaacagcg gacagtcgat gcgtgacttc aatgaaaaac tggcgatttt gaacttcagc
     4981 cgctttaccg cgcccacgct ggtaacgacc cgttccgccg atgtccgcgc atttttgaaa
     5041 gaacacggcg acattatcat caaaccgctg gacggtatgg gcggtatggg tattttccgc
     5101 ctgaccgaaa aagaccccaa catcggcagc atcctcgaaa ccctgatgcg gcttgattcc
     5161 cgcaccatta tggcgcaacg ctacattccc gaaatcgtac acggtgacaa acgcatcctg
     5221 attatcggcg gcgaagtcgt cccctatgct ttggcgcgta tcccgcaaaa cggcgaaaca
     5281 cgcggcaacc ttgcggcagg cggacgcggc gtggcgcagg aattgggcgg acgcgaccgc
     5341 gaaattgccg aaacgctcgc ccccgaactc aaacggcgcg gcatcctgct ggccggtttg
     5401 gacgttatcg gcagcaacct gaccgaagtc aacgtaacca gcccgaccgg attccaagaa
     5461 attatgaaac aaaaaggctt cgatgtggcg gcaatgtttg ccgatgccgt tgccgcgtgg
     5521 tcggtacgtt aaaccgatgc cgtctgaaag gcttttgctt cacaaccgcc tggtttgatc
     5581 gggcaggcag ggttttccct cagtcggcag agatacgctt aataccgtac ggacaccccg
     5641 ccgccccgtt ttcagacggc atatatagtg gattaacaaa aatcaggaca aggcgacgaa
     5701 gccgcagaca gtacaaatag tacggaaccg attcacttgg tgcttcagca ccttagagaa
     5761 tcgttctctt tgagctaagg cgaggcaacg ccgtactggt ttttgttaat ccactatatt
     5821 gagaacattt tgaaaggata ccgatggaac cttcctccta cgcggcagaa aaaaaaggca
     5881 aaggcggcat caggcgcgtc attaacgcat tcggctattc gatagacggc atcgccgccg
     5941 cctaccgtta cgaagcggca ttccgtcagg ttttgtggct gaacgtactg ctggtgtgcg
     6001 cggcattttt ttgggtttcc gaaaccgccg tccgcctgcc gttgattatc gcgtcttttg
     6061 tgtcggtcat tgtcgaactg ttcaacaccg ccgtcgaagc tgccgtcgat catacttcga
     6121 ccgaaaaaca cgagctggcc aaacgcgcca aagacgcagg ttctgccgca caattgttcg
     6181 cgatgctgat gttggcggcg gtttggctgt ctgccctgtt cgggtaaaac gcttgcagca
     6241 ggatttgtaa tcctttagga ttagtatgtg gtatttatta ttcacttaat ctacatcaaa
     6301 tttccaggca gtatttgtat gtatagtgga ttaacaaaaa tcaggacaag gcgacgaagc
     6361 cgcagacagt acaaatagta cggaaccgat ccacttggtg cttcagcacc ttagagaatc
     6421 gttctctttg agctaaggcg aggcaacgct gtactggttt ttgttaatcc gctataagat
     6481 taagcacatt ccccgtctga tattataagg agcagaaaga tgaaaaaatt attggcggcc
     6541 gtgatgatgg caggtttggc aggcgcggtt tccgccgccg gagtccacgt tgaggacggc
     6601 tgggcgcgca ccaccgtcga aggtatgaaa ataggcggcg cgttcatgaa aatccacaac
     6661 gacgaagcca aacaagactt tttgctcggc ggaagcagcc ccgttgccga ccgcgtcgaa
     6721 gtgcataccc acatcaacga caacggcgtg atgcggatgc gcgaagtcga aggcggcgtg
     6781 cctttggagg cgaaatccgt taccgaactc aagcccggca gctatcacgt gatgtttatg
     6841 ggtttgaaaa aacaattaaa agagggcgac aagattcccg ttaccctgaa atttaaaaac
     6901 gccaaagcgc aaaccgtcca actggaagtc aaaatcgcgc cgatgccggc aatgaaccac
     6961 ggtcatcacc acggcgaagc gcatcagcac taatctgctg aaaatgtttg aaatgccgtc
     7021 tgaaaaagcc cgggctttca gacggcattt ttatgaccgc ctttaaaatg tgttaaaatc
     7081 tgcctttaaa aaccgccgtt tccaaccata ttctacgcat gaatacgaca gcaaacacca
     7141 ccaatatcat cgtcgggctc tccggcggtg tcgattcttc cgtaaccgcc gccctgctca
     7201 agcagcaggg ttatcaagtg cgcggtgtgt tcatgcagaa ctgggaagac gacgacaacg
     7261 acgaatattg cagcatcaaa caggattcgt tcgatgccat cgccgttgcc gatattatcg
     7321 gcatcgatat cgacatcgtt aatttcgccg cgcaatataa agacaaagtc tttgcttatt
     7381 ttcttcagga atacagtgcg gggcgcacgc cgaatccgga tgtgttgtgc aacgccgaaa
     7441 tcaaattcaa atgctttttg gactacgccg tagggcaggg cgcggatacc atcgccaccg
     7501 gacactatgc gcgcaaagaa gtccgcaacg gcgtgcatta cctgctcaaa ggtttggatc
     7561 gaaacaaaga ccaaagctat ttcctctacc gcctcaagcc tttccaactc gagcgcgcga
     7621 tttttccgtt gggcggtttg gaaaaacccg aagtgcgccg ccttgccgcc gaatttaatt
     7681 tgccgactgc cgctaaaaaa gacagcacgg gcatctgttt catcggcgaa cgcccgtttc
     7741 gcgagtttct gcagaaatac ctgccgaccg acaatggtaa aatggttacg cccgaaggga
     7801 aaaccgtcgg cgaacacgtc gggctgatgt tctacacgct cggacagcgc aaaggtttgg
     7861 gcattggcgg cgcgggcgaa ccgtggtttg ttgcggctaa agatttgacg aaaaacgaac
     7921 tgattgtcgt gcaaggacac gaccatccgc tgctttatac ccgcagcctt gtgatgaacg
     7981 atttgagttt cacgctgccc gaacgcccga aggcaggacg ctatacctgc aaaacgcgtt
     8041 accgtatggc ggacgcgcct tgtgagttgc gctatttgga tgatgaaacc gccgagctgg
     8101 tgtttgacga accgcaatgg gcggttacgc cgggtcagtc cgccgtgctg tacgacggcg
     8161 atatctgttt gggcggcggt atcatccaaa cgaccgacaa acccgtcatc atcacacgat
     8221 aaaggtaatg ccgtctgaaa cggttttcag acggcattgt tccgctcaat tccactttaa
     8281 agaccgatac ctatgaaaaa aatttggtta gacagctacg agaagggcgt cagtgccgaa
     8341 atcgacatca cgcaatacaa ttccgtcagc gacgtattcc gccaaagcgt ggaaaaattt
     8401 gccgaccaac ctgcttttca aaacatgggt aagacgctga cttatgccga aaccggcaaa
     8461 ctggcaactg atttcgcctc ttatctgcaa aacgtcctca agctgccgcg cggcgaacgt
     8521 gttgccatta tgctgcccaa cgtattgcaa tacccgattg cccttttcgg tattttgcag
     8581 gcaggtttgg tggcggtgaa caccaatccg ctctatacac cgcgcgagtt ggagcatcag
     8641 ttgaaagaca gcggtgcgac cgccatcatc gttttggaaa atttcgccaa cacgctggag
     8701 ctggtgctgc cgcgcacgca gatcaaacac gtcatcgtcg cctccgtcgg cgaaatgttc
     8761 gggctgctta aaggttcgct gatcaatttc atcatccgga aaatcaagaa aatggtgccc
     8821 gaataccgta ttcgggaaac cgtttccttt cagacggcat tgaaagaagg ggcgaagcac
     8881 gttttccaac ctgtcgcatt aaaccgcgaa gataccgcgc tgttgcaata cacgggcggc
     8941 acgacaggtg ttgccaaagg ggcggtgctg agtcacggca acatctgcgc caatatgctt
     9001 caggcaaaag aatggattaa aaaccagttg cgcgagggca aagaaaccgt tatcgccgcc
     9061 ttgccgctgt accatatttt cgccttaacc gtgaatctga tgatttttgc caatgccggc
     9121 tcgaaaatca tcctgattac caacccgcgc gatatgaaag gctttatcgg acaactgaaa
     9181 aaacagcggg ttaatgtatt tatcggcgtg aacacgctgt ttaacgcgat ggttaaccgt
     9241 cctgattttg ccgaagtcga tttttcagga ttgcggctga ctttgggcgg cggtatggcg
     9301 acccaaaaag ccgttgccga aaaatggaaa aaaatcaccg acacgcccat cgtcgaagcc
     9361 tacggtctga ccgaagccag ccccggcgtg tgctgcaacc ccttaaacat cgaatcatac
     9421 agcggcagca tcggtttgcc cgtctcgtcc accgaagtcg aactgcgcga cgcaaacggc
     9481 aaagaagtcc ccgtcgggca gccgggcgaa ttgtgggtaa aaggccctca agtgatgcaa
     9541 ggctactgga accgtcccga agaaaccgct aaagccatag acgcgcgcgg tttcttggaa
     9601 accggcgata ttgccgtcat ggacgaaaaa ggctggttga agctggttga ccgtaagaaa
     9661 gacctcattg ttgtttccgg attcaatgtt tatccgaacg aaatcgaaga agtcatcgcg
     9721 catcacggca aagtgatgga agttgcctgt atcggcgttc ccgacgaaaa aaccggcgag
     9781 gcactcaaag tattcgtcgt cagaaaagac ccgtctttga cgaaagaaga acttatcgcc
     9841 ttttgccgca ccgaattaac cgcatataaa gtaccgaaag atatcgaatt ccgcgacgag
     9901 ttgcccaagt ccaacgtcgg caaaatcctg cgccgcgagt tgcggcaaag taccgggaaa
     9961 taaagaaaag atgccgtctg aaaacagccg tccaccgttc agacggcatc cgtccgtttg
    10021 ccagaaccgc gcgcttcacg ttaaaatcac gcattccaat atgggtattc catcatgacc
    10081 aaattcattt tcgtaaccgg cggcgttgtc tcctcactgg gtaaaggtat cgccgccgct
    10141 tctattgccg ccatcctcga atcgcgcggc ttgaacgtta ccatgctcaa gctcgatcct
    10201 tatatcaacg tcgatcccgg cacgatgagc ccgttccaac acggcgaagt gttcgtaacc
    10261 gacgacggcg cggaaaccga cctcgacttg ggacactacg aacgctttat cgattccacg
    10321 atgacccgcc gcaacagctt cagcacgggg caggtgtacg aaaacgtcat cgccaaagaa
    10381 cgacggggcg actatttggg cggcacggtt caagtcattc cgcacattac cgacgaaatc
    10441 aaacgccgca tccacgaagg cgcggcaggt tacgatgtgg cgattgtcga aatcggcggt
    10501 acagtcggcg atatcgaatc tttgccattc ttggaagcca tccgccaaat gcgcagccag
    10561 ctcggccgca acaatacatt gtttgcccac ctgagctatg ttccttacat tgccgccgcc
    10621 ggtgaaatca aaaccaaacc gacccagcat accgttaagg aaatgttgag cattggtttg
    10681 caaccggaca tcctgatctg ccgtatggac agagaaatgc ctgcggacga gcgccgcaaa
    10741 atcgccttgt tctgcaacgt ggaagaacgc gcgattgtgg gcagctacga cgtggacagc
    10801 atctacgaat gccccgaaat gctgcacgac caaggcatag acaacatcat taccgaacag
    10861 ttgcagctta acgtacaaca ggcggatttg actgcgtgga aaaaaatcgt ccacgccgtc
    10921 aaaaatccga aacacaccgt caaaatcgcg atggtcggca aatacgtcga tttgaccgag
    10981 tcctacaaat cattgattga agccttgaaa cacgcgggta tccacaccga aaccgacgta
    11041 caaattacct ttgttgacag cgaaagcatc gagaaaaaca acggcgacgt ttctatgctc
    11101 aaagatatgg acgccatcct cgttcccggc ggtttcggtt cgcgcggcgt ggaaggcaaa
    11161 atcgccgctg tgcgctatgc ccgcgaaaac aacgtgccat acttgggcat ctgcctcggt
    11221 atgcagattg cgctgatcga atacgcccgc gacgtggcag gtttgaaagg tgcgaattcc
    11281 accgagttcg acctcaaatg cgccgccccc gtcgttgccc tgattgacga atggcaaact
    11341 gccgacggca gcgtcgaaac ccgcgacgaa tccgccgatt tgggcggcac catgcgtttg
    11401 ggcgcgcaag aagtcgaatt gaaaacaggc agcctcgccg ccaaaatcta cggcagcgga
    11461 cacatccgcg aacgccaccg ccaccgctac gaagtcaaca acaactatgt tcctacgctg
    11521 gaacaggcag gtttggtcat cggcggcgta tccgccggac gcgaacgctt ggtcgaaacc
    11581 atcgaactgc cgaaccatcc ttggttcttc gcctgccagt tccaccccga gtttacctcc
    11641 aatccgcgca aagggcatcc tttgttcacc gcgtttgtca aagctgcgtt gaacaataaa
    11701 aaagcctgat aaagcgttac ttgatgatca aaatgccgtc tgaaagcctg aatgaagact
    11761 ttcagacggc attttcgcaa atcggggatt ataaaagcca tcaatttaat ttttatggtt
    11821 tta
//
LOCUS       DAXISH010000063        10967 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.063, whole genome shotgun sequence.
ACCESSION   DAXISH010000063 DAXISH010000000
VERSION     DAXISH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10967
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.063"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..2317
                     /locus_tag="ACFOV4_001741"
     CDS             <1..2317
                     /locus_tag="ACFOV4_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFC7619704.1"
                     /translation="IEIKFTSIQKLYNDIHTERENQTTLADLHELNLVMLGDEAHHLN
                     AQTKGKKQGELDLEVELKANAGDAEFEHKGWEHMVLELLLNKNGNPGQNVLLEFTATP
                     PEKADVQQKYADKIITKFGLKEFLQKGYTKEINLVSSTLSKKERVLHALLFAWYRHQI
                     ALKYGIANFKPVMLFRSKTVDESKADYLAFLNWVENVQADDFSFLKTFSMSLNDSDNA
                     NEQGKTRTEQALKFMQENGFEFAHLANWIKQNYQKHNIIITNSETNKSKTEKTDSETE
                     KLLNNLEAVDNPIRAIFTVGRLTEGWDVLNLFDIVRLYEGQNGGGSNKKSCKTANTTV
                     SEKQLIGRGVRYFPFSFEDKQPNKRKFDNDMQHELRILEELFYYTHDEQSRYITELKN
                     ELRKDGYLPEKDDDKVLATFKLKSEFADNENFKNLLIWANKKIPNPNAKSNNADSLKA
                     NPQTLSFQIHGNQLLQETQFTADKNDEKVKQLGIQNNFSQTIKMSEMERHIFNKALHI
                     KGKNSQSLFHFNRLQSKLNIQNRNELQNNLLKDWQIEFLGLEQDKQVRPDDKLAGCLK
                     ILEMVEKHLNESDKPFIGTKEFTPKTLWEIFGTPKQKWVKKDDIKTAIAMQNDWYVMD
                     NFAGTGLEEALIQFISARLGDLKSQYDIHLIRNEEVFKLNNFANGEGFMPDFILLLKD
                     KQKSSSNGVNDFLHYQIFIEPKGEHLVETDGWKEEFLEAITVEYGMDKILQKDTPHYR
                     LIGLPFFTDHQKNGQFTESFPLGAASLEKMK"
     gene            complement(2461..3633)
                     /locus_tag="ACFOV4_001742"
     CDS             complement(2461..3633)
                     /locus_tag="ACFOV4_001742"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFC7619705.1"
                     /translation="MKRDLSKMTCIEDLRRVAKRKMPRMFYDYIDSGSWTETTYRENT
                     SDFKDIRFRQKVLVNMEGRSLETKMIGQDVKMPVAIAPTGFTGMAHADGEILAARAAE
                     KFGIPFTLSTMSICSIEDVAENTSAPFWFQLYVMRDREFMENLIKRAKDAKCSALVLT
                     ADLQVLGQRHKDIKNGLSAPPKPTIANLINLATKPEWCMKMLNTERRTFRNIVGHAKN
                     VGDLSSLSSWTSEQFDPRLSWDDVARIKDLWGGKLIIKGIMEPEDAEKAAKSGADALI
                     VSNHGGRQLDDTVSAIKALPDIVSAVGSDIEVWMDSGIRSGQDILKAWALGAKGTMIG
                     RAFLYGLGAYGEEGVTRALEILYKEMDISMAFTGHRDIQDVDASILRGKDWGRETV"
     gene            3924..4370
                     /gene="iscR"
                     /locus_tag="ACFOV4_001743"
     CDS             3924..4370
                     /gene="iscR"
                     /locus_tag="ACFOV4_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HFC7619706.1"
                     /translation="MRLTTKGRFAVTAMLDLAMNAQTGAVKLSAISERQNISLSYLEQ
                     LFGKLRRAGLVESLRGPGGGYILAAPAARINIAQIIAAAEDRLDATQCGSKANCHHGA
                     PCLTHDLWENLNKTINDYLGSVTLQSIIEQKNNGDGSRVVQFTHIH"
     gene            4399..5613
                     /locus_tag="ACFOV4_001744"
     CDS             4399..5613
                     /locus_tag="ACFOV4_001744"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0044571 - [2Fe-2S] cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IscS subfamily cysteine desulfurase"
                     /protein_id="HFC7619707.1"
                     /translation="MTVKTPVYLDYAATTPVDKRVAEKMIPYLTETFGNPASNSHSFG
                     WEAEEAVEKARADIAALINADSKEIVFTSGATESNNLAIKGAAHFYKSKGNHLITVKT
                     EHKAVLDTMRELERQGYEVTYLDVQENGLVDLDVLKAAIREDTILVSVMWVNNEIGVV
                     QDIPAIGEICRERKIIFHVDAAQACGKVPVDVEAAKVDLLSMSGHKVYGPKGIGALYV
                     RRKPRVRLEAQMHGGGHERGFRSGTLPTHQIVGMGEAFRIAKEELEQDMAHYRKLRDI
                     FLKGIEGIEEVYVNGDLEHRAPNNLNVSFNFVEGESLIMAVKELAVSSGSACTSASLE
                     PSYVLRALGRNDELAHSSLRITFGRMTTEEEVQFAAELIKSKIGKLRELSPLWEMFKD
                     GIDLNSIEWAAH"
     gene            5680..5808
                     /locus_tag="ACFOV4_001745"
     CDS             5680..5808
                     /locus_tag="ACFOV4_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619708.1"
                     /translation="MNEQDLDLDNLDNLLDDFDGVTVEGGVDSENDDGCEGGACKI"
     gene            5874..6260
                     /gene="iscU"
                     /locus_tag="ACFOV4_001746"
     CDS             5874..6260
                     /gene="iscU"
                     /locus_tag="ACFOV4_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HFC7619709.1"
                     /translation="MAYSDKVIDHYENPRNVGTFDKNDESVGTGMVGAPACGDVMRLQ
                     IKVNDEGIIEDAKFKTYGCGSAIASSSLITEWVKGKSLDDALAIKNSEIAEELELPPV
                     KIHCSILAEDAVKAAVADYRKRQENR"
     gene            6347..6667
                     /gene="iscA"
                     /locus_tag="ACFOV4_001747"
     CDS             6347..6667
                     /gene="iscA"
                     /locus_tag="ACFOV4_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003764837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HFC7619710.1"
                     /translation="MITLTENAAKHINDYLAKRGKGLGVRLGVKTSGCSGMAYNLEFV
                     DEADGDDLIFEGHGARIYIDPKSLVYLDGTQVDYTKEGLQEGFKFENPNVKDSCGCGE
                     SFHV"
     gene            complement(6627..6848)
                     /locus_tag="ACFOV4_001748"
     CDS             complement(6627..6848)
                     /locus_tag="ACFOV4_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor A"
                     /protein_id="HFC7619711.1"
                     /translation="MGGKVQHNKGKIRDNALKALVKSDLFRHKVERKRKGKGSYNRQE
                     AKKWRDGFDTVPPFLCLKHGSFRRSRRSL"
     gene            6930..7430
                     /gene="hscB"
                     /locus_tag="ACFOV4_001749"
     CDS             6930..7430
                     /gene="hscB"
                     /locus_tag="ACFOV4_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001671 - ATPase activator activity
                     [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0044571 - [2Fe-2S] cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly co-chaperone HscB"
                     /protein_id="HFC7619712.1"
                     /translation="MSQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFE
                     QKQAVMMSSTINDAYRTLKNPIDRAAYLLKTSGIDADAPEHTAFAPEFLMQQMEWRET
                     LMEARAGNDLESLKNLDNEIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRN
                     EISSAL"
     gene            7528..10278
                     /gene="gyrA"
                     /locus_tag="ACFOV4_001750"
     CDS             7528..10278
                     /gene="gyrA"
                     /locus_tag="ACFOV4_001750"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFC7619713.1"
                     /translation="MTDATIRHDHKFALETLPVSLEDEMRKSYLDYAMSVIVGRALPD
                     VRDGLKPVHRRVLYAMHELKNNWNAAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQ
                     NFAMRYVLIDGQGNFGSVDGLAAAAMRYTEIRMAKISHEMLADIEEETVNFGPNYDGS
                     EHEPLVLPTRFPTLLVNGSSGIAVGMATNIPPHNLSDTVNACLRLLDAPDTEIDELID
                     IIQAPDFPTGATIYGLSGVREGYKTGRGRVVMRGKTHIEPIGRNGEREAIVIDEIPYQ
                     VNKAKLVEKIGDLVREKTLEGISELRDESDKSGMRVVIELKRNENAEVVLNQLYKLTP
                     LQDSFGINMVVLVDGQPRLLNLKQILSEFLRHRREVVTRRTLFRLKKARHEGHIAEGK
                     AVALSNIDEIIKLIKESPNAAEAKDKLLARPWRSSLVEEMLTRSGLDLEMMRPEGLAA
                     NIGLKEQGYYLSEIQADAILRMSLRNLTGLDQEEIVESYKNLMGKIIDFVDILSKPER
                     ITQIIRDELEEIKTNYGDERRSEINPFGGDIADEDLIPQREMVVTLTHGGYIKTQPTT
                     DYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRN
                     SRGRPINNVIQLEEGEKVSAILAVREFPEDQYVFFATAQGMVKKVQLSAFKNVRAQGI
                     KAIALKEGDYLVGAAQTGGADDIMLFSNLGKAIRFNEYWEKSGNDEAEDADIETEISD
                     GIEDETADSENALPSGKHGVRPSGRGSGGLRGMRLPADGKIVSLITFAPETEESGLQV
                     LTATANGYGKRTPIADYSRKNKGGQGNIAINTGERNGDLVAATLVGETDDLMLITSGG
                     VLIRTKVEQIRETGRAAAGVKLINLDEGETLVSLERVAEDESELSDASVISNVTEPEV
                     EN"
     gene            10435..10838
                     /locus_tag="ACFOV4_001751"
                     /pseudo
     CDS             10435..10838
                     /locus_tag="ACFOV4_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060537127.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3267 a         2834 c         2450 g         2416 t
ORIGIN      
        1 cattgaaatt aaatttacca gtattcaaaa actgtataac gatatccaca ccgaacggga
       61 aaaccaaacc acattggcag atttgcacga attgaacctt gtgatgctgg gcgatgaagc
      121 gcaccattta aacgcacaaa ccaaaggcaa aaaacaaggc gagttggatt tggaagtgga
      181 attaaaagcc aatgcaggcg atgccgaatt tgaacacaaa ggctgggagc atatggtttt
      241 ggaattgttg ctcaataaaa atggcaatcc cggccaaaat gtgctgttgg aatttaccgc
      301 cacgccacct gaaaaagctg acgtgcaaca aaaatacgct gataaaatca tcacaaaatt
      361 tggtttaaaa gaatttttgc aaaaaggtta taccaaagaa atcaatttgg tatccagtac
      421 actgagcaag aaagagcggg tgttgcacgc tttattgttt gcttggtatc gccatcaaat
      481 cgctttgaaa tatggcattg ccaatttcaa gcctgtgatg ttgtttagaa gtaagacggt
      541 tgatgaatca aaagcggatt atttggcatt tttaaattgg gtagaaaatg tgcaagcaga
      601 tgatttttcg tttttaaaga cattttcaat gagcttaaac gatagcgata acgccaacga
      661 acaaggcaaa acccgcaccg aacaagccct aaaatttatg caggaaaatg gctttgagtt
      721 tgcacattta gcaaattgga taaaacaaaa ttatcaaaaa cacaatatca ttattaccaa
      781 ctccgaaacc aacaaaagca aaaccgaaaa aaccgacagc gaaacggaaa aattgctaaa
      841 caatctggaa gcggttgata atccgattcg tgctattttt acggtgggta gattaaccga
      901 aggttgggac gttttaaatt tgtttgatat tgtgcgtttg tatgaagggc aaaacggcgg
      961 cggttcaaat aaaaaatcat gcaaaacggc aaatacaacg gtatcagaaa aacagttgat
     1021 tggtcgaggc gtgcgttatt ttccattttc gtttgaagat aaacagccga ataagcgtaa
     1081 atttgacaac gacatgcaac acgaattgcg tattttggaa gaattgtttt attacacgca
     1141 cgatgagcaa tcccgctata ttacagaact gaaaaacgag ttacgaaaag acggttattt
     1201 gcctgaaaaa gacgatgata aggtattggc aacatttaaa ctcaaatctg aatttgcaga
     1261 taatgaaaat tttaaaaact tattgatttg ggcgaataaa aaaatcccca atcccaatgc
     1321 taaaagtaat aatgcagaca gcctaaaagc caatccgcaa acactttcat tccaaattca
     1381 cggcaatcaa ctgttgcagg aaacgcaatt tacagccgat aaaaatgatg aaaaggtcaa
     1441 gcaacttggc atacaaaata atttttctca aaccataaaa atgagtgaaa tggaacggca
     1501 catcttcaat aaagcattac atatcaaagg gaaaaatagt caatctttat tccatttcaa
     1561 ccgtttgcaa agcaaactca acattcaaaa tcgcaatgaa ttgcaaaata acttgttgaa
     1621 agactggcaa attgaatttt taggattaga gcaagataaa caggttcgcc cggatgataa
     1681 acttgcaggc tgcctgaaaa tcttggaaat ggttgaaaag catttgaatg aaagtgataa
     1741 gccatttatc ggtacaaaag aatttacgcc taaaacatta tgggaaattt tcggcacgcc
     1801 aaaacaaaaa tgggtcaaaa aagatgatat aaaaactgct attgccatgc aaaatgattg
     1861 gtatgtgatg gataattttg ccggaacggg tttggaagaa gcgttaattc aatttatttc
     1921 agcgcgtttg ggcgatttga aatctcaata tgacattcat ttaatccgta acgaagaagt
     1981 gtttaaattg aataactttg ccaatggcga aggatttatg cccgacttta ttttattgct
     2041 gaaagataaa caaaaatctt cttccaatgg cgtgaatgac tttttgcatt accaaatttt
     2101 cattgagccc aaaggtgagc atttagtgga aactgatgga tggaaagaag aatttttaga
     2161 agccatcaca gtggaatatg ggatggataa gatcctgcaa aaagatacac cgcattatcg
     2221 tttgatcggt ttaccgtttt ttactgatca tcagaaaaat ggacaattta cggagtcatt
     2281 ccctttaggt gcggcatcgc ttgaaaaaat gaagtagtgc attgcaggca gccccgtttg
     2341 acaaaacttc ctttacaaaa gggcgttttg tcagatattt aatcaacaca ttattaaaat
     2401 acagccaaat tttaatgccg tctgaaccct gtgttcagac ggcatcgtat ttttcagtat
     2461 ctaaaccgtt tccctacccc aatccttacc cctcaaaatc gaggcatcga catcttgaat
     2521 atcgcggtgt cccgtaaacg ccatagatat atccatttct ttatacagga tttccagcgc
     2581 acgggttacg ccttcttcgc catacgcacc caagccatac agaaacgccc gacctatcat
     2641 tgtacctttc gcacccaaag cccacgcctt caaaatatcc tgaccgctgc ggatgccgct
     2701 gtccatccaa acttcgatgt cgctgccgac tgcactaacg atgtcgggca aggctttgat
     2761 ggcagacacg gtatcgtcga gctgtcggcc gccgtggttg gaaacaatca atgcgtccgc
     2821 gccgcttttc gctgcttttt ccgcgtcttc gggttccata atgcctttga taatcagctt
     2881 gccgccccac aaatctttaa tgcgcgccac atcgtcccag ctcaggcgcg ggtcgaattg
     2941 ttcggaagtc catgaagaca gcgaagacaa atcgccgacg ttcttcgcgt gtccgacgat
     3001 attgcggaac gtgcggcgtt ccgtgttcag cattttcatg caccattccg gtttggtcgc
     3061 cagattgatt aaattggcga tggtcggttt cggcggcgcg gacaggccgt ttttgatgtc
     3121 tttgtggcgt tgacccaaaa cctgcaaatc ggcggtcaat accaatgccg aacatttggc
     3181 atccttcgcg cgcttaatca ggttttccat aaactcgcgg tcgcgcatca cataaagctg
     3241 aaaccaaaat ggtgcggaag tgttctcggc aacgtcttca atcgagcaga tagacatcgt
     3301 ggacagcgta aacggaatgc cgaacttctc cgccgcccgc gccgccaaaa tttcaccgtc
     3361 ggcgtgtgcc atacccgtga aacccgtcgg cgcaatcgcc accggcattt tcacatcctg
     3421 cccgatcatt ttggtttcca ggcttcggcc ttccatattg accaatacct tttgtcggaa
     3481 gcggatgtct ttgaaatccg aagtgttttc acggtaggta gtttctgtcc acgaacccga
     3541 atcgatgtaa tcgtaaaaca tacgcggcat tttgcgcttg gcaacgcggc gcaagtcttc
     3601 gatgcaggtc attttgctca aatcacgttt catttgtcgc cccctgaata cctgaataac
     3661 tttatatgaa atcgataatg tatatcaata ttgattataa ggcaaatcat ttcaacattt
     3721 gccgcatccg ccgcagctcc ctactttaag cgacataagg tttaaaattc aaaaataaca
     3781 aattaaaatc aaaatattaa aaatcaatca atctatcgat ttaaacagcc aatcacacaa
     3841 tccgccccca tacttgactg aaacactcag atattggaca attccaccca ctaataaaaa
     3901 aaccgacatg ggcaaccacc accatgagac tgaccaccaa agggcgtttc gccgttaccg
     3961 ctatgctgga tttggcgatg aacgcgcaaa ccggcgccgt caaactcagt gccatcagcg
     4021 aacgccaaaa catatccctc tcctatctcg agcaattgtt cggcaaactc cgccgcgccg
     4081 gacttgttga aagcctgcgc gggcccggcg gcggctacat cctcgccgca ccggcggcac
     4141 gcatcaacat cgcccaaatc atcgccgccg ccgaagaccg gctggacgca acccaatgcg
     4201 gcagcaaagc caactgccac cacggcgcgc cctgcctgac gcacgatctt tgggagaatt
     4261 taaacaaaac catcaacgac tacctcggca gcgttaccct gcaaagcatc atcgaacaga
     4321 aaaacaacgg cgacggcagc cgcgtcgtcc aatttacaca catccattaa ataacacccg
     4381 aaaaagaaag agcaaaccat gaccgtcaaa acccccgttt acctcgacta cgccgccacc
     4441 acccccgttg acaaacgcgt tgccgaaaaa atgattccct atctgaccga aaccttcggc
     4501 aacccagcct ccaacagcca cagcttcggc tgggaagcag aagaagctgt agaaaaagca
     4561 cgtgcagaca ttgccgccct gattaacgcc gactctaaag aaatcgtttt caccagcggc
     4621 gcaaccgagt ccaacaacct cgctatcaaa ggcgcggcgc acttctacaa atctaaaggt
     4681 aatcacctca tcactgtaaa aaccgaacac aaagccgtac tcgacaccat gcgcgaactc
     4741 gaacgccaag gttacgaagt aacttatctg gacgtacaag aaaacggttt ggttgattta
     4801 gacgtactga aagccgccat ccgcgaagac accatcctcg tttccgtaat gtgggtaaac
     4861 aacgaaatcg gcgtggttca agatattcct gccatcggcg aaatctgccg cgaacgcaaa
     4921 atcattttcc acgttgacgc agcacaagca tgcggcaaag tgcctgttga tgttgaagcc
     4981 gcaaaagttg atttgctgtc tatgtccggc cacaaagtat acggccctaa aggcatcggc
     5041 gcgctgtacg tccgccgcaa accccgcgtc cgcctcgaag cccaaatgca cggcggcggc
     5101 cacgaacgcg gcttccgcag cggcacattg ccgacccacc aaatcgtcgg tatgggcgaa
     5161 gccttccgca tcgccaaaga agaactcgaa caagatatgg cgcactaccg caaactgcgc
     5221 gacatcttcc tcaaaggcat cgaaggcatc gaagaagtct atgtcaacgg cgacctcgaa
     5281 caccgcgccc cgaacaacct gaacgtcagc ttcaacttcg tcgaaggcga aagcctgatt
     5341 atggcggtga aagaactcgc cgtatccagc ggctccgcct gtacttctgc cagtctcgaa
     5401 cccagctacg tcctgcgcgc gctcggccgc aacgatgaac tggcgcactc atccctgcgc
     5461 atcaccttcg gtcgcatgac cactgaagaa gaagtgcaat ttgccgccga actgattaaa
     5521 tccaaaatcg gcaaactgcg cgaactgtcg ccgttgtggg aaatgttcaa agacgggatt
     5581 gatttgaact cgattgaatg ggcggcgcat taaagcgtac caacatgcca tccgaacctt
     5641 cagacggcat tccaaaaaca aagcaatcaa gagaaaaata tgaacgaaca agatttagat
     5701 ttggacaacc tcgacaacct gcttgacgat ttcgacggcg ttaccgtgga aggcggcgtc
     5761 gattcggaaa acgacgacgg ctgtgaaggc ggagcgtgca aaatctaact caggccgtct
     5821 gaaaaccggc aaacaaacca cttaaatcat caaaacatta aggaaaccac atcatggcat
     5881 acagcgataa agtaatcgac cactacgaaa atccccgcaa cgtcggtact ttcgacaaaa
     5941 acgacgaatc tgtcggcacc ggcatggtcg gcgcaccggc ctgcggcgac gtgatgcgcc
     6001 tgcaaatcaa agtgaacgat gaaggcatca tcgaagatgc gaaattcaaa acttacggct
     6061 gcggttccgc catcgcttcg tccagcctga ttaccgagtg ggttaaaggc aaaagcctgg
     6121 atgacgcgct ggcaatcaaa aacagcgaaa tcgccgaaga gttggaattg ccgccggtaa
     6181 aaatccactg ctccatcttg gctgaagatg cggtaaaagc ggccgttgcc gactaccgca
     6241 aacgtcagga aaacagataa agcccttcag acggcatcgt cccgcaatgc cgtccgaacc
     6301 gcccgccgct tcgggttcgt ccgaggcggt acaacaagga agaaatatga ttacccttac
     6361 cgagaatgcc gcaaaacaca tcaatgacta tctcgccaaa cgcggcaaag gcttgggcgt
     6421 acgcttgggt gtgaaaacca gcggctgctc ggggatggcg tacaaccttg aatttgtcga
     6481 tgaagccgat ggcgacgacc tgattttcga aggacacggc gcacgcattt atatcgaccc
     6541 gaaaagcctg gtttatctgg acggcacaca agtcgattac accaaagaag gtttgcagga
     6601 aggtttcaaa tttgaaaacc ccaatgtcaa agactcctgc ggctgcggcg aaagcttcca
     6661 tgtttaagac ataaaaatgg cgggaccgta tcaaaaccgt cccgccattt tttcgcttcc
     6721 tgcctgttgt agctgccttt gccttttctt ttccgttcca ccttgtgtcg gaacaaatca
     6781 gatttcacta aggcttttaa agcattgtcg cgtattttgc ctttattgtg ctgcactttg
     6841 ccgcccatat tcagtccttt cgtttaagaa gcggcagatt ataaggcaaa aacagttttc
     6901 tgccaaaatc ttacatttat catcctacta tgtcccaata tttcaccctc ttccggattg
     6961 aacccgcttt cgatatcgac accgaaaact tggaacaaac ctaccgcgcc ttggccgccc
     7021 gtttccatcc cgataaattc gcttcagctt ccgcctttga gcaaaagcag gcagtgatga
     7081 tgtcttccac catcaacgat gcctaccgca ccttgaaaaa ccccatcgac cgcgccgcct
     7141 acctgctgaa aacatcgggc atcgatgccg acgcgccgga gcataccgct ttcgcccccg
     7201 aattccttat gcagcaaatg gaatggcgcg aaacgctgat ggaggcacgg gcaggcaacg
     7261 accttgaatc cttgaaaaat ctcgacaacg aaatccgcga cgaacaagaa aaactgttct
     7321 gcggtctgaa acagtcgttt gcccgacaag attacgacac agccgcacaa caagtccgcc
     7381 aaggcaggtt tctcgacaaa ctccgcaacg aaatttcctc ggcattataa tccgcaccgt
     7441 gtttcagacg gcgtaaccgc cgcaccgttc cgcgtcaaaa tatgctaaaa taagcaacaa
     7501 ttttttgcca tacgaaacat tgaaaccatg accgacgcaa ccatccgcca cgaccacaaa
     7561 ttcgccctcg aaaccctgcc ggtaagcctt gaagacgaaa tgcgcaaaag ctatctcgac
     7621 tacgccatga gcgtcattgt cgggcgcgcg ctgccggacg ttcgcgacgg tctcaagccg
     7681 gtacaccgcc gcgtactgta cgcgatgcac gagctgaaaa acaactggaa tgccgcctac
     7741 aaaaaatcgg cgcgcattgt cggcgacgtc atcggtaaat accaccccca cggcgatacc
     7801 gccgtatacg acaccatcgt ccgtatggcg caaaatttcg ctatgcgtta tgtgctgata
     7861 gacggacagg gcaacttcgg atcggtggac gggcttgccg ccgcagccat gcgctacacc
     7921 gaaatccgca tggcgaaaat ttcccacgaa atgctggcag acattgagga agaaaccgtc
     7981 aatttcggcc cgaactacga cggtagcgaa cacgagccgc ttgtactgcc gacccgtttc
     8041 cccacactgc tcgtcaacgg ctcgtccggc atcgccgtcg gcatggcgac caatatcccg
     8101 ccgcacaacc tttctgatac cgtcaatgcc tgcctgcgcc tgctcgatgc acccgacacc
     8161 gaaatcgacg aactgatcga cattatccaa gcccccgact tcccgaccgg ggcaaccatc
     8221 tacggcttga gcggcgtgcg cgaaggctat aaaacaggcc gcggccgcgt cgttatgcgc
     8281 ggtaagaccc atatcgaacc cataggcaga aacggcgaac gcgaagccat cgttatcgac
     8341 gaaatcccct atcaggtcaa caaagccaag ctggtcgaga aaatcggcga tttggttcgg
     8401 gaaaaaacac tggaaggcat ttccgagctc cgcgacgaat ccgacaaatc cggtatgcgc
     8461 gtcgttatcg agctgaaacg caacgaaaat gccgaagtcg tcttaaacca actctacaaa
     8521 ctgactccgc tgcaagacag tttcggcatc aatatggtgg ttttggtcga cggacaaccg
     8581 cgcctgttga acctgaaaca gattctctcc gaattcctgc gccaccgccg cgaagtcgtt
     8641 acccgacgta cgcttttccg gctgaagaag gcacgccatg aagggcatat cgccgaaggc
     8701 aaagcggtcg cactgtccaa tatcgatgaa atcatcaagc tcatcaaaga atcgcccaac
     8761 gcagccgagg ccaaagacaa actgcttgca cgtccttggc gcagcagcct cgttgaagaa
     8821 atgctgacgc gttccggtct ggatttggaa atgatgcgtc cggaaggatt ggctgcaaac
     8881 atcggcttga aagagcaagg ttattacctg agcgagattc aggcagatgc tattttacgc
     8941 atgagcctgc gaaacctgac cggcctcgat caagaagaaa ttgtcgaaag ctacaaaaac
     9001 ctgatgggta aaatcatcga ctttgtggat atcctctcca aacccgaacg cattacccaa
     9061 atcatccgcg acgaactgga agaaatcaaa accaactatg gcgacgaacg ccgcagcgaa
     9121 atcaacccgt tcggtggcga cattgccgat gaagacctga ttccgcaacg cgaaatggtc
     9181 gttaccctga cacatggcgg ctatatcaaa acccagccga ccaccgacta tcaggcgcag
     9241 cgtcgcggcg ggcgcggcaa acaggcggct gccaccaaag acgaagactt tatcgaaacc
     9301 ctgtttgttg ccaacacgca tgattatttg atgtgcttta ccaatttggg caagtgtcat
     9361 tggattaagg tttacaaact gcccgaaggc ggacgcaaca gccgcggccg tccgattaac
     9421 aacgtcatcc agttggaaga aggcgaaaaa gtcagcgcga ttctggcagt acgcgagttc
     9481 cccgaagacc aatacgtctt cttcgccacc gcgcagggaa tggtgaaaaa agtccaactt
     9541 tccgccttta aaaacgtccg cgcccaaggc attaaagcca tcgcgctcaa agaaggcgac
     9601 tacctcgtcg gcgctgcgca aacaggcggt gcggacgaca tcatgctgtt ctccaactta
     9661 ggtaaagcca tccgcttcaa cgaatactgg gaaaaatccg gcaacgacga agcggaagat
     9721 gccgacatcg aaaccgaaat ttcagacggc atcgaagatg aaaccgccga cagcgaaaac
     9781 gcactgccga gcggcaaaca cggtgttcgc ccgtccggtc gcggcagcgg cggtttgcgc
     9841 ggtatgcgcc tgcctgccga cggcaaaatc gtcagcctga ttaccttcgc ccctgaaacc
     9901 gaagaaagcg gtttgcaagt tttaaccgcc accgccaacg gatacggaaa acgcaccccg
     9961 attgccgatt acagccgcaa aaacaaaggc gggcaaggca atattgccat taacaccggc
    10021 gagcgaaacg gcgatttggt cgccgcaacc ttggtcggcg aaaccgacga tttgatgctg
    10081 attaccagcg gcggcgtact tatccgcacc aaagtcgaac aaatccgcga aaccggccgc
    10141 gccgcagcag gcgtgaaact gattaacttg gacgaaggcg aaaccttggt atcgctggaa
    10201 cgtgttgccg aagacgaatc cgaactctcc gacgcttctg taatttccaa tgtaaccgaa
    10261 ccggaagtcg agaactgaaa atcatctccc gatgccgtct gaagattcag acggcattta
    10321 ttttatccct catccgtcat ccagcttctc acaatatagc ggattatagt caattaaaaa
    10381 caaggggctg tcctagataa ctagggaaat tcaaattaag ttagagttgc ccctatgaga
    10441 aaaagtcgtc taagccggta taaacaaata aactcattga actgtttgtc gcaggtgtaa
    10501 ctgcaagaac gacagcagag ttagtaggcg ttaataaaag taccgcagcc tattattttc
    10561 atcgtttacg attacttatt tatcaaaaca gtccgcattt ggaaatgttt gatggcgaag
    10621 tagaagcaga tgaaagttat tttgctgaac gacaaaacca tatcaatgga attgagaact
    10681 tttggaaccg ggcaaaacgt catttacgca agtttgacgg cattcccaaa gcgcattttg
    10741 agctgtattt aaaggggtac gaacggcgtt ttaacaacag tgagataaaa gttcaaattt
    10801 ccattttaaa acaattagta aaatcgagtt tatcctagtt atctaggaca gccccaaaaa
    10861 caaaatagta caatattcaa ctttgaaggt ctaaccatgg catactctgc ggacttaaga
    10921 aacaaagctt taaactatag tggattaaat ttaaatcagg acaaggc
//
LOCUS       DAXISH010000064        10696 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.064, whole genome shotgun sequence.
ACCESSION   DAXISH010000064 DAXISH010000000
VERSION     DAXISH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10696
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.064"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            61..1434
                     /locus_tag="ACFOV4_001752"
     CDS             61..1434
                     /locus_tag="ACFOV4_001752"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFC7619714.1"
                     /translation="MSNPFSSLGLGTELVSALTAQGYENPTPIQAAAIPKALAGHDLL
                     AAAQTGTGKTAAFMLPSLERLKRYATASTSPAMHPVRMLVLTPTRELADQIDQNVQGY
                     IKNLPLRHTVLFGGMNMDKQTADLRAGCEIVVATVGRLLDHVKQKNIHLNKVEIVVLD
                     EADRMLDMGFIDDIRKIMQMLHRQRQTLLFSATFSAPIRKLAQDFMNAPETVEVAAQN
                     TTNANVEQHIIAVDTFQKLNLLERLIVDLHMNQVIVFCKTKQSVDRVTRELVRRNLSA
                     QAIHGDRSQQSRLETLNAFKDGSLRVLVATDIAARGLDIAELPFVINYEMPAQPEDYV
                     HRIGRTGRAGADGVAISLMDESEQKMFESIKELTGNKLLIERIEGFEPQWWEQGGAKP
                     EKTEMREPRQRNRYESAKAQREKNTRPENAANDAGAACGKIAGRSRRSRREHRTCALL
                     QPRYGVK"
     gene            1670..2695
                     /locus_tag="ACFOV4_001753"
                     /pseudo
     CDS             1670..2695
                     /locus_tag="ACFOV4_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003680490.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
     gene            3130..4257
                     /gene="fic"
                     /locus_tag="ACFOV4_001754"
     CDS             3130..4257
                     /gene="fic"
                     /locus_tag="ACFOV4_001754"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFC7619715.1"
                     /translation="MSNWKPNIPYNDLPPLPPKQDIESKTILKRCIAARASLARLKQA
                     AELIPNQAMLINTLPVMEARASSEIENIVTTTDKLFQSLQMDTERQDPATKEALQYRT
                     ALFAGYESLTSRPLCTQTAIMVCNAIKHPYEMAIRKTGGTALKGGNSGNVVYTPPEGE
                     ETIRGKLANWERFIHESGDLDPLIIMAAAHYQFEAIHPFTDGNGRTGRILNSLLLIEK
                     GLLDLPILYLSRYIIENRADYYRLLLGVTERQDWESWIIYILDGVADTADWTVAKIDA
                     IRRLFEQTRQHIRTHAQGIYTHELVNLLFEQPYTRIANLEAAGIAKRQTASKYLKELS
                     DIGVLQEIAIGRDKLFIHPRLMELLRGEGNSFTSFQSLVKA"
     gene            4287..5165
                     /locus_tag="ACFOV4_001755"
     CDS             4287..5165
                     /locus_tag="ACFOV4_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC7619716.1"
                     /translation="MARRSKTFEEAAAEVEERFGHRGIKLVEFEGTAKPCVINCPKHG
                     NQTCSRYSNMFIGSSWGCPSCGNEQAAKAGIATLRKNHIALEMLKQAVTGMTKQERIT
                     TQAYNEMTKSVAGSNSIVLNDVQGDTTINNHHTHTHNHSDADGKALSMRLTPRPLLSD
                     RQAAAFARTGKLTGSFDLFASVVAPSQYTFAVAMPDTSMSPVIEKGDLVVVEPRMRPA
                     DEDIVLIELSDKRLVVAHLVIDIAGRMLIYQTGRPSEAFDLPEGSTILGVVLEVKKRF
                     MSAAQARRRVDSDYHP"
     gene            5169..5357
                     /locus_tag="ACFOV4_001756"
                     /pseudo
     CDS             5169..5357
                     /locus_tag="ACFOV4_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311460.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5434..6945)
                     /gene="lysS"
                     /locus_tag="ACFOV4_001757"
     CDS             complement(5434..6945)
                     /gene="lysS"
                     /locus_tag="ACFOV4_001757"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFC7619717.1"
                     /translation="MSEQNHPQTEPQLDENQIIALRREKLHNIRQQRNAYPNDFKRDS
                     FAADLHTQYGEIGKEELDPQGIPVKIAGRMMLKRQMGKASFATIQDVSGQIQLYLNNK
                     GVSQEILDDFNHWDLGDIVGAEGTLFKTNHGELTVRVSGIRLLSKSLRPLPDKHKGLS
                     DQETKYRQRYVDLIANGESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGAT
                     AKPFVTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTM
                     IEFYEAFSDYERMMQMAEDIIRNASRTVNGTANITYNGKEVDLESPFERLTILEAIKK
                     YNPHYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIIDY
                     PVEVSPLARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKSQVAQKDAGD
                     DEAMHYDADYIRAMEFGLPPTGGCGIGIDRLVMLLTDSQTIRDVILFPQMRPE"
     gene            complement(7100..8353)
                     /locus_tag="ACFOV4_001758"
     CDS             complement(7100..8353)
                     /locus_tag="ACFOV4_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HFC7619718.1"
                     /translation="MSEQHISTWKSKINALGPGIMMASAAVGGSHLIASTQAGALYGW
                     QIALIIILTNLFKYPFFRFSAHYTLDTGKSLIEGYAEKSRVYLWVFLILCIISATINA
                     GAVAIVTAAIVKMAIPSLMFDAGTVAALIMASCLIILVSGRYRALDRVSKIIIVTLSI
                     ATLAAAGIAMSRGMQMQPDFIEPTPWTLAGLGFLIALMGWMPAPIEISAINSLWVTEK
                     QRINPSEYRDGIFDFNVGYIASAVLALVFLALGAFVQYGNGEAVQMAGGKYIGQLINM
                     YAVTIGGWSRPLVAFIAFACMYGTTITVVDGYARAIAEPVRLLRGKDKTGNAEFFAWN
                     IWVAGSGLAVIFWFDGVMANLLKFAMIAAFVSAPVFAWLNYRLVKGDEKHKLTSGMNA
                     LALAGLIYLTGFTVLFLLNLAGMFK"
     gene            8811..10607
                     /locus_tag="ACFOV4_001759"
     CDS             8811..10607
                     /locus_tag="ACFOV4_001759"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017146933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFC7619719.1"
                     /translation="MNTVSNYLSALREAMKAQGLDALVIPSADPHLSEYLPEHWQARR
                     ELSGFTGSVGTFVLTTDEAGVWVDSRYWEQAAKQLAGSGIELQKSGQVPPYNEWLAAN
                     LPENAAVGIPSDMVSLTGKRTLAQSLTAKNIRIEHPDDLLDQVWTSRPAIPAETVFIH
                     DPAYVSETAAEKLARVRAVMAEKGADYHLVSSLDDIAWLTNLRGSDVPFNPVFVSFLL
                     IGKDNAVLFTEQCRLNAEAAAALQTAGITVEPYAQVADKLAQIGGALLIEPNKTAVST
                     LVRLPESVRLIEGTNPSTLFKSCKSEADIARIREAMEHDGAALCGFFAEFEDIIGNGG
                     SLTEIDVDTMLYRHRSVRPGFVSLSFDTIAGFNANGALPHYSATPESHSTISGNGLLL
                     IDSGAQYKGGTTDITRVVPVGTPTAEQKRDNTLVLKAHIALAEAVFPENIPSPLIDAI
                     CRKPLWQAQCDYGHGTGHGVGYFLNVHEGPQRIAFAAPATPETAMKKGMVTSIEPGLY
                     RPGKWGIRIENLAANQAVAAPQETEFGSFLCFETLTLCPIDTRLMDTALMTDGEIDWV
                     NRYHAEVRRRLEPLTEGAAKAWLIKRTEPLAR"
BASE COUNT         2686 a         3074 c         2689 g         2247 t
ORIGIN      
        1 tccccgtcct atcggtttcc cgtttcagac gacataaggt ctgaaagaaa gactacaatt
       61 atgagtaatc cattttcctc tttaggtttg ggtacggaac tcgtttccgc actgaccgcg
      121 caaggttacg aaaacccgac gcccatccaa gccgccgcca ttcccaaagc actcgccggt
      181 catgatttgc tagccgccgc gcaaaccggc acaggcaaaa ccgccgcctt tatgctgccc
      241 agtctggaac gcctcaaacg ttacgccacc gccagcacct cgcccgcgat gcaccccgtg
      301 cgtatgctcg tcctcacccc cacgcgcgaa cttgccgacc aaatcgacca aaacgtgcag
      361 ggctacatca aaaacctgcc gctgcgccac accgtcttgt tcggcggtat gaatatggac
      421 aaacagaccg ccgatttgcg cgccggctgc gaaatcgtcg tcgccaccgt cgggcggctg
      481 ctcgaccacg tcaaacaaaa aaacatccat ttgaacaaag tagaaattgt cgttttggat
      541 gaagccgacc gtatgctgga tatgggtttt atcgacgaca tccgcaaaat catgcagatg
      601 ctgcaccgcc aacgccaaac cctgctcttt tccgccacct tctccgcccc gatacgcaaa
      661 ctggcgcaag acttcatgaa cgcgcccgaa accgtcgaag tcgccgcgca aaacaccacc
      721 aacgccaacg tcgaacaaca catcatcgcc gtcgatacct tccaaaagct caacctgctc
      781 gaacggctga ttgtcgatct gcatatgaac caggtcatcg tgttctgcaa aaccaaacaa
      841 agcgtcgacc gcgtaacgcg cgaactggtg cgccgcaacc tgtccgcaca ggcgatacac
      901 ggcgaccgtt cccaacaaag ccggctcgaa acactcaacg ccttcaaaga cggcagcctg
      961 cgcgtcctcg tcgccaccga catcgccgcg cgcgggctgg acattgccga actgcccttc
     1021 gtcatcaatt acgaaatgcc cgcccagccc gaagactacg tccaccgcat cgggcgcacg
     1081 gggcgcgcgg gcgcggacgg cgtggcgatt tccctgatgg acgaatccga acagaaaatg
     1141 tttgaatcca ttaaagagct gaccggcaac aagctgctca tcgagcgcat cgagggcttc
     1201 gagccgcaat ggtgggaaca gggcggcgca aaaccggaaa aaaccgaaat gcgcgaaccg
     1261 agacaacgca accgctacga atccgccaaa gcgcaacgcg aaaaaaacac ccggccggaa
     1321 aatgcggcaa acgatgcggg cgcggcttgc ggaaaaattg ccggacgcag ccgccgaagc
     1381 cgccgggaac accggacgtg cgccctgctc caaccgcgtt acggcgtaaa atagccctga
     1441 aaatcaaatg ccgtctgaac atttcccgtt tcagacggca tttttcaaac cggactgacg
     1501 catcgggagc aaccgcccgc accggataaa tttctgccgc aaacagtttc agacggcatt
     1561 tgctgcctgt acaatatagt ggattaacaa aaattaggac aaggcggcga gccgcagaca
     1621 gtacaaatag tacggaaccg attcacttgg tgcttcagca ccttagagaa tcgttctctt
     1681 tgagctaagg cgaggcaacg ccgtactggt ttttgttaat ccactatatc aagtctgcgt
     1741 gttggaaaaa cagcactttc cgcgcttcgt catcggcgaa agcctgctgc cgcactgtat
     1801 ggaaatgctg gaagaagccg gatttgccga tgccgtgcgc gccgagcccg gctttcagtt
     1861 gaaaaacggc gcggcgtttt cgtggggcag ccgttatacc gaattcgatt tcaccgataa
     1921 attttcagac ggccccggca cgacttatca agtgcgccgc gccgtgttcg ataaaatcct
     1981 gattgaagaa gccgccaaac aaggcgttga agtacgtttc gggcacggcg taaccgcgtt
     2041 cgacaacagc ggcgattttg tccgcctgaa catcgaaacc gacaccggca agcgctatga
     2101 actgaccgcg aaattcgtct tggacgcaag cggttacgga cgcgtgctgc cgcgcctgct
     2161 aaacttggaa acgccctcgc acctgccgcc gcgccaagcg catttcacgc acatcgacga
     2221 caacatcacc aacccgaaat tcgaccgcaa caaaatcctg attaccacct atccgcaaca
     2281 ccgcgacgtg tggatttggc tgattccctt cggcgacaac cgctgttccg tcggcgtggt
     2341 cggcacgccc gacaaacttg ccggcgaatc ggaaacagtg ttgaaaaaat ttgtttacaa
     2401 atgcccgatg ctgaacgaaa ttttggacaa agccgtttgg gaaaacgatt ttccgttccg
     2461 ctccatccaa ggctattccg ccaatgtgaa atcgctgcac ggcaggcatt tcgcgctatt
     2521 gggcaatgcc gccgagttcc tcgatcccgt gttctcgtcg ggcgtaacca tcgcgctgca
     2581 ctccgccaaa cttgccgccg atctgttggc aaaacaactc aaaggcgaag ccgccgattg
     2641 gcaaaccgaa tttgccgaac ccttgatgat cggcgtggac gcgttccgca cctatagtgg
     2701 attaaattta aatcaggaca aggcaacgaa gccgcagaca gtacaaatag tacggaaccg
     2761 attcacttgg tgcttcagca ccttagagaa tcgttctctt tgagctaagg cgaggcaacg
     2821 ccgtactggt ttaaatttaa tccactaaat agtgtatatt aagtacgtct gatatacgcg
     2881 ataccctccg agggtgtaaa ctttagttca catttaaaat gacctcttta aacctgtctt
     2941 tcggcaggtt tctttttagg ttgtttggaa atcgtgtgca gacaaggtgt aaaataggta
     3001 acaacataaa ataatgcggt tttaccgccc atatatttac aaaagccaaa tttttaaaca
     3061 tatatccttg atatatacac ggcgtaaaca tatactggaa acatctttaa attttccgaa
     3121 attttaaata tgagcaactg gaaacccaat attccctata acgatttacc acccctgccg
     3181 ccaaaacagg atattgaaag caaaaccatc ctgaaacgtt gtatagccgc ccgtgcatcc
     3241 cttgcccgtt taaagcaggc ggcagaactg ataccgaatc aagccatgct gattaacacc
     3301 cttcctgtta tggaagcccg tgcaagttcg gaaattgaaa acatcgtaac cacaacggat
     3361 aagctgtttc aatccctgca aatggatacg gaacggcaag accctgccac gaaagaagcc
     3421 ctgcaatacc gcaccgccct gtttgcaggc tatgaatcac tgacgagccg ccctttatgc
     3481 acacaaaccg ccatcatggt ctgcaacgcc atcaagcacc cctacgaaat ggccatccgc
     3541 aaaacaggcg gcacagccct aaaaggaggc aacagcggaa atgttgtcta taccccgccc
     3601 gaaggagaag aaaccatacg cggcaagctg gcaaattggg agcggtttat tcacgaaagc
     3661 ggcgatttag acccgcttat catcatggcg gcggcacatt accaatttga agccatccat
     3721 ccgtttacgg acggcaacgg gcggacgggg cgcatattga acagcctgct attgattgaa
     3781 aaagggcttt tggatttgcc tattttgtat ttgagccgct acatcatcga aaacagggcg
     3841 gactattacc gcctgctttt aggcgtaacc gaacggcagg actgggaaag ctggataatc
     3901 tacatcttag acggcgtagc cgacaccgcc gattggacgg tagcgaaaat agatgcgata
     3961 cgccgcctgt ttgagcagac acgtcaacac atacggacac acgcacaagg aatctacacg
     4021 cacgaactgg taaatcttct gtttgagcag ccatatacac gcattgccaa cctagaagcg
     4081 gcagggatag ccaaacggca gacggcctct aagtacctga aagagctttc agacataggt
     4141 gtgctgcaag aaatcgccat cggcagggac aaactattca ttcatccgcg cctaatggaa
     4201 ctattgcggg gagagggcaa cagctttacc tcattccaat ccctcgttaa agcatagcca
     4261 aaataatcaa taatccggag gtcaatatgg caagaaggtc aaaaacattt gaagaagctg
     4321 ctgctgaggt tgaggaacgt ttcggtcatc gtggcattaa gttggtcgag tttgagggta
     4381 cagccaagcc gtgtgtaatc aactgcccta aacatggaaa ccaaacctgt tcgaggtact
     4441 ccaatatgtt cataggaagt agctggggtt gcccctcttg tggtaatgag caagctgcaa
     4501 aagccggtat agcgaccctt aggaagaatc acatagcgtt agaaatgctg aaacaggctg
     4561 taacaggtat gaccaagcaa gagcgcatca cgacgcaagc ctacaatgag atgaccaaat
     4621 ccgtggcagg ttcaaacagc atagtcctta acgatgtcca aggcgatacg accatcaaca
     4681 accatcatac gcatacgcac aaccacagcg atgccgacgg caaagcactg tcgatgaggc
     4741 tcacaccacg ccccctgttg tcagaccgtc aggcggcggc tttcgcccgt acaggcaaac
     4801 tcacaggcag tttcgacttg tttgcttcgg tggtcgcccc ctcgcagtac acgtttgccg
     4861 ttgccatgcc cgacacgtcc atgtcgccgg ttatcgaaaa aggggatttg gtggtggtcg
     4921 agccgcgtat gcgccctgcg gacgaggaca tcgtgctgat tgaactgtcc gacaagcggc
     4981 tggtcgtcgc gcaccttgtt atcgatattg cgggcaggat gctgatttat cagacgggca
     5041 ggccgtctga agcctttgac ctgcccgaag gcagcacgat tttaggtgtg gtgctggagg
     5101 tcaaaaaacg gtttatgtcc gccgcacagg cgagaaggcg tgttgattcg gattaccacc
     5161 cctgatgtgt ggacggttgg tacgatttcc gcttccaaaa cgtcgtgtac gcgcccgacc
     5221 gcagcccgga aatcagccgt atgctttctt cgattttggc aggctacgcg tgggataccg
     5281 aaaacccgtt cgtggcgaaa tccgaacaac gcctgactgc cttgtccgaa tgggtcggtc
     5341 agttagaaag cgaataaatc cgtaccgcca tacaaaatgc cgtctgaatc caatcgggtt
     5401 cagacggcat tgccatttca actgttttta tgactactcg gggcgcatct gcggaaacag
     5461 aatcacatcg cggatggttt gcgaatcggt cagcaacatc accaagcggt cgataccgat
     5521 gccgcaaccg ccggtcggcg gcaaaccaaa ttccatcgcg cggatgtagt cggcatcgta
     5581 atgcatggct tcgtcgtcgc ccgcgtcttt ttgtgcgact tgcgatttga agcgttcggc
     5641 ttggtcttca gggtcattca attctgaata gccgtttgcc agttcgcggc cgacaacgaa
     5701 caattcgaaa cgttcggtca gaccttgttt ggtatccgaa gcgcgcgcca acggggaaac
     5761 ttcgaccggg taatcgatga tgaaggtcgg gttccacagc ttgccctcgg cgcaaccttc
     5821 aaacagcgcg agttgcaggc tgccgatgcc cggggacggc ggcaggcttt caccgtgttt
     5881 gacgatttct tttttcagcc attccgcatc gttcaactgc tcgtcggtgt agtgcggatt
     5941 gtattttttg atggcttcga ggatggtcag acgctcgaac gggctttcca aatcgacttc
     6001 tttgccattg taagtgatgt ttgccgtacc gtttactgtg cgcgatgcgt tgcggatgat
     6061 gtcttctgcc atctgcatca tacgttcgta gtcggagaag gcttcgtaga attcgatcat
     6121 ggtgaattcg ggattgtggc gcacggacat accttcgttg cggaagctgc gattgatttc
     6181 aaacacgcgc tccaaaccgc cgacaaccaa gcgtttcaga tacagctcgg gggcgatgcg
     6241 caggtagagc ggaatgtcca aggcattgtg gtgggtaacg aagggttttg ccgtcgcgcc
     6301 gccgggaatc gggtgcatca tcggggtttc gacttcgaga taatgctcgc ccaccataaa
     6361 attacgcacg gattggatga tttggctgcg tttgatgaag gtattgcgcg attctccgtt
     6421 ggcaatcaaa tcaacatagc gttggcggta tttggtttcc tgatcgctca aacctttgtg
     6481 tttgtcgggc agcggacgca gggatttgga cagcaggcgg atgccggaca cgcgtacggt
     6541 cagttcgccg tggttggttt tgaacaaagt gccttccgca ccgacgatgt cgcccaagtc
     6601 ccaatggttg aagtcgtcca aaatttcttg gctcacgcct ttgttgttca gataaagctg
     6661 gatttgcccg gacacgtctt gaatggtggc aaagctcgcc ttgcccattt gccgtttgag
     6721 catcatgcgg ccggcaattt tgacgggaat gccttgcggg tcgagttctt ctttgccgat
     6781 ttcaccgtat tgggtatgca ggtcggcggc aaagctgtcg cgtttgaaat cgttagggta
     6841 ggcgttgcgc tgttggcgga tgttgtgcag tttttcgcgg cgcagggcga tgatttggtt
     6901 ttcgtccaac tgcggctcgg tttgcggatg gttttgttcg ctcatagggt tttccgaaaa
     6961 aataaatcag gcgcaatctg tttcagacga cctgaccgaa tcacaaaatt tgcgcatatt
     7021 ttacgcgatg tcggtgtttt tttccataaa cgcggcaatg ccgtctgaaa gcggtttgcg
     7081 gtttcagacg gcatcgttat catttgaaca ttcccgccaa attcaatagg aacaaaacgg
     7141 taaagccggt cagataaatc aagcctgcca atgcaagggc attcatacct gatgtgagtt
     7201 tgtgtttttc atcacctttg accaaacggt aattcagcca ggcaaacaca ggggcggaca
     7261 caaaagcggc aatcatcgca aatttgagca gattcgccat tacgccgtca aaccaaaaaa
     7321 tcaccgccaa accgctgccc gccacccaaa tattccaggc aaagaattcg gcgttgcccg
     7381 ttttgtcttt tccgcgcagc aggcgcacgg gttcggcaat ggcacgggca tagccgtcca
     7441 caacggtaat cgtcgtgccg tacatgcagg caaaagcgat aaacgccacc agcgggcgcg
     7501 accagccgcc gatggtaacg gcgtacatat tgatcaattg cccgatatat ttgccgcccg
     7561 ccatctgcac tgcttcgccg ttgccgtatt gcacaaacgc gcccagtgca aggaaaacca
     7621 aagccaaaac cgcactggcg atataaccga cgttgaaatc aaaaatcccg tcgcggtatt
     7681 cggaaggatt gatgcgttgt ttttcggtta cccacaaaga attgatggcg gaaatttcaa
     7741 tcggcgcggg catccagccc atcagcgcga tcaggaagcc caaaccggca agcgtccacg
     7801 gtgtcggctc gataaagtcc ggctgcatct gcataccgcg cgacatagcg atgccggcgg
     7861 cggcaagcgt ggcgatactc aaagtaacga tgatgatttt ggaaacgcga tccaaagcgc
     7921 ggtaacgtcc gctcaccaaa ataatcaggc aggatgccat aatcaaggca gcaaccgtgc
     7981 cggcatcaaa catcagcgag ggaatcgcca ttttgacgat ggcggcggtt acgatggcga
     8041 ccgcgccagc gttaatcgtg gcggaaatga tgcacaaaat caggaaaacc cacaaataaa
     8101 cacggctttt ctcggcataa ccttcaatca ggctcttgcc cgtgtccagc gtgtaatgcg
     8161 cgctgaagcg gaaaaacggg tatttgaaga ggttggtcag gatgatgatg agcgcgatct
     8221 gccagccgta aagcgcgccc gcctgcgtcg aggcaatcag gtgcgaaccg ccgaccgccg
     8281 ccgaagccat catgatcccc ggacccaatg cgttgatttt acttttccaa gtcgaaatat
     8341 gttgttcgga cataaagtct tccgtatttt taactgtgtt tcaacacaca gagccgcata
     8401 ttcggacaca gccctatcta ttgctccaat ttgggcggga ttgcccccaa acaaacccaa
     8461 atcctaccgt cttcaaaaac aggataccgc tcggtaggga aattttgatg aaaacacgta
     8521 ttgtaacgta atccaaatac ctgccaacac acactattag aacttcatgc tcaaacttga
     8581 ctatattttc catattactt ccaaaaaaag gcataaaacg acattttatg cctaaaattt
     8641 tacaacaaac aaccttacat cgcttttttc gcgcaaacac gcaccatccg atcagcccgt
     8701 ccgttttgca gcaggctggc gatttgataa gatggttatg tttttcagac ggcatttcag
     8761 atttccgtcc atgccgtctg aagccgcaaa acccgattgg aggaactgtt atgaataccg
     8821 tatcgaatta cctgtccgca ttgcgcgaag ccatgaaggc gcaaggcttg gacgcgctcg
     8881 tcatcccttc cgccgacccc cacctgtccg aatacctgcc cgagcattgg caggcgcgcc
     8941 gcgaattatc gggctttacc ggctcggtcg gcacgtttgt cctgaccacc gatgaagcgg
     9001 gcgtatgggt ggacagccgc tattgggaac aagccgccaa gcagcttgcg ggcagcggca
     9061 tcgaactgca aaaaagcggg caagtgccgc cgtataacga atggctcgcg gcaaacctgc
     9121 ccgaaaacgc cgccgtcggc atcccttccg atatggtctc gctcaccggc aaacgcactt
     9181 tggcgcaatc cctgaccgcc aaaaacatcc gcatcgaaca cccggacgat ctgcttgacc
     9241 aagtgtggac aagccgtccc gctatccccg ccgaaaccgt gttcatccac gaccccgcct
     9301 acgtctccga aaccgccgcc gaaaaactcg cccgcgtgcg cgccgtgatg gcggaaaaag
     9361 gcgcggatta ccacttggtt tcatcgcttg acgacatcgc ttggctgacc aacctgcgcg
     9421 gcagcgacgt gcctttcaat cccgttttcg tgtccttcct gctgattggc aaagacaacg
     9481 ccgtcctgtt taccgaacaa tgccgtctga acgccgaagc cgccgccgcg ctgcaaaccg
     9541 ccggcatcac ggtcgaacct tacgcccaag ttgccgacaa gctcgcgcaa atcggcggcg
     9601 cgctgcttat cgaaccgaac aaaaccgccg tcagtacgct cgtgcgcctg cccgaaagcg
     9661 tacgcctaat cgaaggcacc aacccgtcca cgctgttcaa atcctgcaaa tccgaagccg
     9721 acatcgcccg catccgcgaa gcgatggaac acgacggcgc ggcgttgtgc ggtttcttcg
     9781 ccgagtttga agacatcatc ggcaacggcg gcagcctgac cgaaatcgac gtggacacca
     9841 tgctttaccg ccaccgcagc gtgcgcccgg gttttgtgtc attgagtttc gacaccatcg
     9901 caggcttcaa cgccaacggc gccctgccgc attacagcgc aacgcccgaa agccacagca
     9961 ccatcagcgg caacgggctg ctgctcatcg actccggcgc gcaatacaaa ggcggcacga
    10021 ccgacatcac ccgcgtcgtc cctgtcggca cacccaccgc cgaacaaaaa cgcgacaaca
    10081 ccctcgttct caaagcccat atcgcgcttg ccgaagccgt gttcccagaa aacatcccct
    10141 cgccgctgat tgatgcgatt tgccgcaaac ccctgtggca ggcgcaatgc gactacggcc
    10201 acggcaccgg acacggcgta ggctatttcc tcaacgtcca cgaaggcccg cagcgcatcg
    10261 ccttcgccgc ccccgccacg cccgaaaccg ccatgaaaaa aggcatggtt acctccatcg
    10321 aacccggact ctaccgcccg ggaaaatggg gcatccgcat tgaaaacctt gccgccaacc
    10381 aagccgtcgc cgcccctcaa gaaaccgaat tcggcagctt cctctgtttt gaaaccctga
    10441 ccctctgccc catcgacacc cgcctgatgg acaccgccct catgaccgac ggcgaaatcg
    10501 actgggtcaa ccgctaccac gccgaagtcc gccgccgcct cgagccgctg accgaaggcg
    10561 cggcaaaagc gtggctgatc aaacgcaccg aaccgctggc gcgttaaaca gcacggcgca
    10621 aaaaatgccg tctgaaagcc cttcagacgg cattggtttc ccaaaacatc ccgcaccgtt
    10681 ttcatcttgc cgcaag
//
LOCUS       DAXISH010000065        10325 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.065, whole genome shotgun sequence.
ACCESSION   DAXISH010000065 DAXISH010000000
VERSION     DAXISH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10325
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.065"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..483)
                     /locus_tag="ACFOV4_001760"
     CDS             complement(<1..483)
                     /locus_tag="ACFOV4_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HFC7619720.1"
                     /translation="MIEWRFDQGRLDYFRFDEIKKIAKGLYGINQCPKPRAKDIDIVR
                     LSLTQETNLPFAPNSSQYPVWRNYGRVFKCLLLATEHNGLICTTDLCADLVQNDEISC
                     DDYLLHFATHFSYPSPAFSGYQPSENRVFPVLAIIRALISKYKETGVNFLDMDEIIYK
                     I"
     gene            complement(525..3374)
                     /gene="uvrA"
                     /locus_tag="ACFOV4_001761"
     CDS             complement(525..3374)
                     /gene="uvrA"
                     /locus_tag="ACFOV4_001761"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFC7619721.1"
                     /translation="MCNHHPQHSHDNDTIRIRGARTHNLKNVDLDIPRHKLVVVTGLS
                     GSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTS
                     HNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHNLPLSSQTVSQMVDAVLKLPEDTRVM
                     ILAPAVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRV
                     KVKANIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPVCSYSLPELEPRL
                     FSFNNPMGSCPTCDGLGNTNFFDSEKVVAHPELSLASGAIDGWDKRNQFYFQMIQSLA
                     RHYGFDVQAAWETLPAKIKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLER
                     RYRETDSETVREKLREYQNHRACPSCGGARLRKEARYVYVSGEPLHEVSAWPLTKTHQ
                     FFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRIRLAS
                     QIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFV
                     VDMGPGAGEHGGNVLIADTPENVAKCENSITGQYLSGKKSIAVPSERTPVNPDRMLVL
                     KGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPYD
                     DIRGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFS
                     FNVKGGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLD
                     MTVEEAREFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRD
                     TGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGP
                     EGGDSGGRIIAQGSPEEVAKVKGSYTGKYLKVVLG"
     gene            3529..4326
                     /locus_tag="ACFOV4_001762"
     CDS             3529..4326
                     /locus_tag="ACFOV4_001762"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HFC7619722.1"
                     /translation="MNRLYPHPIIAREGWPIIGGGLALSLLVSMCCGWWSLPFWVFTV
                     FALQFFRDPAREIPQNPEAVLSPVDGRIVVVERARDPYRDVDALKISIFMNVFNVHSQ
                     KSPADCTVTKVVYNKGKFVNADLDKASTENERNAVLATTASGREITFVQVAGLVARRI
                     LCYTQAGAKLSRGERYGFIRFGSRVDMYLPVDAQAQVAIGDKVTGVSTVLARLPLTAP
                     QIESEPESEPALQTAPVETAANPSAEQRQIEAAAAKIQAAVQDVLKD"
     gene            complement(4471..4578)
                     /locus_tag="ACFOV4_001763"
                     /pseudo
     CDS             complement(4471..4578)
                     /locus_tag="ACFOV4_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(5557..7833)
                     /gene="znuD"
                     /locus_tag="ACFOV4_001764"
                     /gene_synonym="tdfJ"
     CDS             complement(5557..7833)
                     /gene="znuD"
                     /locus_tag="ACFOV4_001764"
                     /gene_synonym="tdfJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_118820519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent zinc receptor ZnuD"
                     /protein_id="HFC7619723.1"
                     /translation="MAQTTLKPIVLSILLINTPLLAQAHETEQSVDLETVSVVGKSRP
                     RATSGLLHTSTASDKIISGDTLRQKAVNLGDALDGVPGIHASQYGGGASAPVIRGQTG
                     RRIKVLNHHGETGDMADFSPDHAIMVDTALSQQVEILRGPVTLLYSSGNVAGLVDVAD
                     NKIPEKMPENGVSGEAGLRLSSGNLEKLTSAGINIGLGKNFVLHTEGLYRKSGDYAVP
                     RYRNLKRLPDSRADSQTGSIGLSWVGEKGFIGVAYSDRRDQYGLPAHSHEYDDCHADI
                     IWQKSLINKRYLQLYPHLLTEEDIDYDNPGLSCGFHDDDNAHAHTHSGRPWIDLRNKR
                     YELRAEWKQPFPGFEALRVYLNRNDYRHDEKAGDAVENFFKNKTQNARIELRHQPIGR
                     LKGSWGVQYLQQKSSALSATSEAVKQPMLIDNNVRHYSFFGVEQANWDNFTLEGGVRV
                     EKQKASIRYDKALIDRENYYNHPLPDLGAHRQTARSFALSGNWYFTPQHKLSLTASHQ
                     ERLPSTQELYAHGKHVATNTFEVGNKHLNKERSNNIELALGYEGDRWQYNLALYRNRF
                     GNYIYAQTLNDGRGPKSIEDDSEMKLVRYNQSGADFYGAEGEIYFKPTPRYRIGVSGD
                     YVRGRLKNLPSLPGREDAYGNRPFIAQDDQNAPRVPAARLGFHLKASLTDRIDANLDY
                     YRVFAQNKLARYETRTPGHHMLNLGANYRRNTRYGEWNWYVKADNLLNQSVYAHSSFL
                     SDTPQMGRSFTGGVNVKF"
     gene            8255..8845
                     /locus_tag="ACFOV4_001765"
     CDS             8255..8845
                     /locus_tag="ACFOV4_001765"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HFC7619724.1"
                     /translation="MLLFIDNYDSFTYNIVQYFAELGQEVAVRRNDDITLEEIEALNP
                     QYLVIGPGPCSPKEAGISVAAMRHFAGRLPIMGVCLGHQTIGEAFGGRIVRAKTLMHG
                     KVSPVSHSGKGMFKGLPNPVTCTRYHSLVIDRDNLPDCLEITAWTDDGEIMGVRHKEY
                     AVEGVQFHPEALLTEHGHDMLNNFLIEFQNFKPQKI"
     gene            8908..9966
                     /gene="trpD"
                     /locus_tag="ACFOV4_001766"
     CDS             8908..9966
                     /gene="trpD"
                     /locus_tag="ACFOV4_001766"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HFC7619725.1"
                     /translation="MITPQQAIERLISNNELFYDEMTDLMRQIMRGQVLPEQIAAILT
                     GLRIKVETVSEITAAAAVMREFATKVPLENAEGLVDIVGTGGDGAKTFNISTTSMFVA
                     AAAGAKVAKHGGRSVSSSSGAADVVEQMGANLNLTPEQIAQSISQTGIGFMFAPNHHS
                     AMRHVAPVRRSLGFRSIFNILGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHV
                     LVVCGEGGLDEITLTGKTRVAELKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESL
                     LKMNEVLDGKEGAARDIVLLNTAAALYAGNVAASLSDGISAAREAIDSGRAKSKKEEF
                     VGFQPQQRCHFLGKMELG"
     gene            complement(10023..10325)
                     /locus_tag="ACFOV4_001767"
                     /pseudo
     CDS             complement(10023..10325)
                     /locus_tag="ACFOV4_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003684347.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS1595 family transposase"
BASE COUNT         2397 a         2411 c         2868 g         2649 t
ORIGIN      
        1 gattttgtaa ataatttcat ccatgtccaa aaaattaact cctgtttcct tatattttga
       61 aattaaagct ctaataattg ccaaaacagg gaaaacccga ttttcagatg gttgatatcc
      121 tgaaaaagct ggtgatgggt aggaaaaatg tgttgcaaaa tgtagtaaat aatcatcgca
      181 actaatttca tcattctgaa ctaaatcggc acataaatct gtagtacaga ttaacccatt
      241 atgctccgtt gcgagtaaca aacatttaaa aacacgacca taattacgcc aaactggata
      301 ttgtgaactg ttaggggcaa aaggtaagtt tgtctcttga gtcaggctta atcttacaat
      361 atcaatatct tttgcacgtg gctttggaca ttgattaatt ccatataatc cttttgcaat
      421 ttttttaatt tcatcaaatc taaaataatc taatctacct tgatcaaaac gccattcaat
      481 catttttaac ctctatgaaa tatcattttt cagtaatctg aaaattatcc taaaaccacc
      541 ttcaaatact tcccagtata actcccctta accttcgcca cttcctcagg gctaccttgg
      601 gcaataatcc tccccccgct atcgccacct tccggtccta aatctacaat ccaatccgca
      661 gttttaatca catccagatt atgctcaata atcacaatcg agttgccttt gcctttcaga
      721 cggcctatga cttccagcag cagggcgatg tcggcgaagt gcaggccggt ggtgggttcg
      781 tcgaggatgt agagcgttct gccggtgtcg cgtttggaga gttccaaggc gagtttgacg
      841 cgctgggctt cgccgccgga gagggtggtg gcggactggc cgaggcggat gtagccgaga
      901 cctacgtcca tcagggtttg cagtttgcgc gatacggtgg ggacggcgtc gaaaaattcg
      961 cgggcttctt cgacggtcat gtcgaggact tggctgatgt ttttgccttt gtattggatt
     1021 tcgagggttt cgcggttgta gcgtttgccg tggcagactt cgcaggggac gtacacgtcg
     1081 ggcaggaagt gcatttcgac tttaatcacg ccgtcgcctt ggcaggcttc gcagcggccg
     1141 cctttgacat tgaaggagaa tctgccgacg ttgtagccgc gttcgcgcga gagggggacg
     1201 ccggcgaaga gttcgcggat gggggtgaac aggccggtgt aggtggcggg gttggagcgc
     1261 ggggtgcggc cgatggggga ttggtcgacg ttgatgactt tgtcgaggtg ttcgaggccg
     1321 cggatgtcgt cgtatggggc gggttcttct tgggcgcggt tgagttcgcg ggcggtgatt
     1381 ttggcgaggg tgtcgttaat cagggtggat ttgccgctgc cggatacgcc ggtgatgcag
     1441 gtaatcaaac cgagcggcag ttcgagggta acgtttttga ggttgttgcc gcgcgcgcct
     1501 ttgaggacga gcatccggtc gggattgacg ggtgtgcgtt cagacggcac ggcaatggat
     1561 tttttgccgc tgaggtattg tccggtaatg gagttttcgc atttggcgac gttttcgggt
     1621 gtgtcggcaa tcagtacgtt gccgccgtgt tcgccggcgc ccgggcccat atcgacgacg
     1681 aaatcggctt cgcggatggc atcttcgtcg tgttcgacca caatcacgct gttgcctaaa
     1741 tcgcgcaggc gtttgagggt ggcgagcagg cggtcgttgt cgcgctggtg caggccgatg
     1801 gagggttcgt ccaaaacgta cattacgccg gtcaggccgc tgccgatttg gctggcgagg
     1861 cggatgcgct gggcttcgcc gccggaaagg gtttcggcgg aacgggagag attcaggtaa
     1921 tccagcccga cattaatcaa aaagccgaga cgttcggtga tttctttgag gattttttcg
     1981 gcgatttgtt ttttgttgcc gtctaaatcc agtgtttcaa agaattggtg ggttttggtg
     2041 agcggccagg cggaaacttc gtgcaacggc tcaccgctga cgtaaacgta gcgggcttct
     2101 ttgcgcaaac gtgcgccgcc gcagctcggg caggcgcggt ggttttggta ttcgcgcagt
     2161 ttttcgcgca cggtttcgct gtcggtttcg cggtagcggc gttcgagatt ggggatgatg
     2221 ccttcgaagg cgtggctgcg gttgaaggtg gtgccgcgtt cggacaggta agtgaaatca
     2281 atgacttcct tgcccgagcc gtgcaacacg acttttttga tttttgcagg tagggtttcc
     2341 caagcagcct gcacgtcgaa accgtaatgc cgcgccagcg actgaatcat ttggaaatag
     2401 aactggttgc gcttgtccca gccgtcaatc gcgcccgaag ccagcgacaa ttcgggatgc
     2461 gcgaccactt tttcggagtc gaagaaattg gtgttgccca agccgtcgca agtcgggcag
     2521 gagcccatcg ggttgttgaa cgaaaagagg cgcggctcca attcgggcag gctgtacgaa
     2581 catacggggc aggcgaaacg cgcggaaaac caatgctctt cgccgctgtc catttccatc
     2641 gccagcgcgc gctcgttgcc gtggcgcagc gcggtttcaa aactttccgc cagccgctgc
     2701 ttgatgttcg ccttcacttt cacgcggtcg atgaccacgt cgatattgtg tttgatgttt
     2761 ttttccagct tcggcacttc gtcaagctga tagacctcgc cgtccacgcg cacacgggca
     2821 aagccttgcg cctgcaagtc agcaaagaag tcgacaaact cgcccttacg ctcacgaact
     2881 gccggcgcaa gaatcatcac gcgcgtgtct tccggcagtt ttaatacggc atcgaccatc
     2941 tgagatacgg tttggctgga tagcggcaga ttgtgttcgg ggcaatacgg tgtgccgacg
     3001 cgtgcgtaca aaaggcgcag gtaatcgtgg atttccgtaa ccgtgccgac ggtggaacgc
     3061 ggattgtggc tggtggattt ctgctcgatg gaaatcgcgg gcgacagacc ctcgatcaaa
     3121 tcgacatcgg gtttgtccat catctgcaaa aactgccgcg cataggcgga caggctctcg
     3181 acataacgcc gctgtccttc ggcatacagc gtgtcgaacg ccagcgatga tttgccgctg
     3241 cctgacaatc ctgttaccac caccagcttg tggcgcggaa tgtctaaatc gacgtttttc
     3301 aaattatgcg tgcgcgcgcc gcgtatgcgg atggtgtcgt tgtcgtgcga atgttgggga
     3361 tgatggttgc acataatgga tgccgcctga aaaataaagg aaaactggta ttgtagcact
     3421 ttctcggatg ccgtctgaag ccgcgttcag acggcatttg tcggcggagt acggcagatt
     3481 ccgctataat gtcggcaatt ttaacccgct tgaacaaaag gatgacaaat gaaccgtctt
     3541 tacccccacc cgattatcgc ccgtgagggc tggccgatta ttggcggcgg tttggctttg
     3601 agcctgctgg tgtcgatgtg ttgcggctgg tggtctttgc cgttttgggt gtttaccgta
     3661 tttgccctgc agtttttccg cgaccctgcg cgtgagattc cgcaaaatcc tgaagcagtg
     3721 ttgagtccgg ttgacggccg tatcgtggtg gtcgagcgcg cacgcgatcc gtatcgtgat
     3781 gtcgatgctt tgaaaatcag tatttttatg aacgtgttca acgtgcattc gcaaaaatcg
     3841 cctgccgatt gtacggtaac gaaagtggtc tataacaaag gcaaattcgt gaatgcggat
     3901 ttggacaaag ccagcacgga aaacgaacgt aatgcggtgt tggcgactac ggcttccggt
     3961 cgtgaaatta cttttgttca agtggccggt ttggtggcgc gccgtatttt gtgctacacc
     4021 caagcaggtg cgaaactgtc ccgcggcgaa cgttatggct ttatccgctt cggttcgcgc
     4081 gtggatatgt atctgcctgt cgatgcgcag gcgcaagtgg cgattggcga taaagtaact
     4141 ggcgttagca ctgtattggc gcgtttgccg ctgactgcgc cgcaaatcga atccgagcct
     4201 gagtctgagc ctgctttaca aactgctccg gttgaaacag cggcaaaccc atctgccgaa
     4261 caacggcaaa tcgaggcagc ggcggctaag attcaggcgg ctgtgcaaga tgtgttgaaa
     4321 gattaatttt gcgaactgaa atagaaaata tcagtaccat cattcacacg aatgaggaag
     4381 tttggttttt tgaatttttg ctaatgttca caccgttatg ttcacgaaaa tgggaatctg
     4441 gaaatttaac gttacggtga tttatcagaa atatagtgga ttaaatttaa accagtacgg
     4501 cgttgcctcg ccttgccgta ctatttgtac tgtctgcggc ttcgtcgcct tgtcctgatt
     4561 taaatttaat ccactataac agaaactgaa cgaattagat tcccgcctgc gcgggaatga
     4621 caactcatta gttacctaac acttaaaaaa cagaaacctt tccgcgtcat tcccacgaaa
     4681 gtgggaatcc gggaacttaa cgttacagtg atttatcgga aacgactgaa accgaagaga
     4741 ccggattccc gcctgcgtgg gaatgacaac tcattagtta cttaaaactt aaaaaacaga
     4801 aacctttacg cgtcattccc acgaaagtgg gaatccggga acttaacgtt acagtgattt
     4861 atcggaaacg gctgaaaccg aacgaattgg attcccgcct gcgcgggaat gacgactcat
     4921 tagttaccta aaacttaaaa aaaacagaaa cctttccgcg tcattcccat gaaagtggga
     4981 atctagaacc caaatgctaa ggcgatttat cggaaacggc tgaaaacgaa gagactggat
     5041 tcccgcctgc gcgggaatga caactcatta gttacctaaa acttaaaaaa cagaaacctt
     5101 tacgccgtca ttcccacgaa agtgggaatc tagaacccaa atgctaaggc gatttatcgg
     5161 aaacggctga aaccgaacga attggattcc cgcctgcgca ggaatgacaa ctcattagtt
     5221 acctaaaact taaaaaacag aaacctttac accgtcattc ccacgaaagt gggaatctag
     5281 aacccaaatg ctaaggcgat ttatcggaaa cggctgaaac cgaatgaatt ggattcccgc
     5341 ctgcgcggga atgacgggat cttgggtttc tgcttttgat ttttctgctt ttgcgagaat
     5401 gacggcgtga aagtaagaat gatgaaacaa aaaaaatggg aatgatggca tagtggtttg
     5461 ttctttgtct ttgccatatt tcctaacaaa ttgattaaaa agaaaaaagg ttttcagaat
     5521 gccgtctgaa aacctttttt gtttgcctgt ccgattttaa aacttcacgt tcacgccgcc
     5581 ggtaaagctg cggcccattt gcggcgtatc agagagaaag ctgctgtggg cgtaaacgga
     5641 ttggttgagc aggttgtcgg ctttgacgta ccaattccac tcgccatagc gcgtattgcg
     5701 gcggtagttt gcgccgaggt tgagcatatg gtgtccgggc gtgcgcgttt cgtagcgggc
     5761 gagtttgttt tgggcaaaca cgcggtagta gtccaaattg gcatcgatgc ggtcggtcag
     5821 cgaggctttc aggtggaagc cgaggcgcgc agccggaacg cgaggggcgt tttggtcgtc
     5881 ctgcgcgatg aaaggacggt tgccgtaggc atcttccctg ccgggtaggg acggcaggtt
     5941 tttcagacgg cctcgtacat agtcgccgga aacgccgatg cggtagcgcg gtgtcggttt
     6001 gaagtagatt tcgccttccg cgccgtagaa gtccgcaccg gattggttgt agcgcacgag
     6061 cttcatttcg ctgtcgtctt cgatggattt ggggccgcgt ccgtcgttta aggtttgggc
     6121 gtaaatgtag ttgccgaagc ggttgcggta gagtgccaga ttgtattgcc agcggtcgcc
     6181 ttcgtagccc aacgcgagtt cgatgttgtt ggaacgctct ttgttcaggt gtttgttgcc
     6241 gacttcaaaa gtgttggtgg caacgtgttt gccgtgtgcg tacagctctt gcgttgacgg
     6301 caggcgttcc tgatgggagg cggtcaggct gagtttgtgt tgcggcgtga aataccagtt
     6361 gcccgaaagt gcgaacgagc gggcggtttg gcggtgcgcg ccgaggtcgg gcagggggtg
     6421 gttgtagtag ttttcccgat caatcaatgc tttgtcgtac cggatggagg ctttttgttt
     6481 ttccacgcgt acgccgcctt caagcgtgaa gttgtcccag tttgcctgtt ctacaccgaa
     6541 aaagctgtaa tggcgcacat tgttgtcaat caacatcggt tgtttgaccg cttcggatgt
     6601 ggcagataaa gcactggatt tttgttgtaa atattgcacg ccccagctgc ctttcagacg
     6661 gcctatgggt tggtggcgca actcgatgcg ggcgttttgc gttttgtttt tgaagaagtt
     6721 ttccactgca tcgcctgctt tttcgtcgtg gcggtagtcg ttgcggttca agtatacgcg
     6781 cagggcttca aaaccgggga acggttgctt ccattcggca cggagttcgt agcgtttgtt
     6841 gcgcaggtct atccacggtc tgccgctgtg ggtgtgtgcg tgtgcattat cgtcgtcgtg
     6901 gaagccgcag ctcaagcccg gattgtcgta atcgatgtct tcttcggtca acaggtgcgg
     6961 ataaagctgt aaatagcgtt tgttaatcaa gctcttttgc cagatgatgt cggcgtggca
     7021 atcatcgtat tcgtggctgt gggcaggcag accatattgg tcgcgacggt cgctgtacgc
     7081 tacgccgata aaaccttttt cgccaaccca agacagcccg atgctgcccg tttgcgaatc
     7141 ggcgcggctg tcgggcaggc gtttcagatt gcggtaacgc ggtacggcgt aatcgcccga
     7201 tttgcggtac aagccttccg tatgcaatac aaagtttttg cccaagccga tattgatgcc
     7261 tgcggatgtc agtttttcca aattgccgct gctcaaacgc aatccggctt cgcccgatac
     7321 gccgttttca ggcatttttt cgggaatttt attgtcggca acatcaacca gccccgcgac
     7381 attgcccgaa ctatataaaa gcgtaaccgg gccgcgcagg atttcgacct gttgcgacaa
     7441 ggcggtatct accataatgg cgtgatcggg cgaaaaatcc gccatatcgc ccgtttcgcc
     7501 gtgatggttc aaaaccttaa tccgcctgcc tgtttgaccg cgtatcaccg gtgcggacgc
     7561 gccgccgccg tattgcgagg cgtgaatacc cggtacgccg tccaaagcat cgcctaagtt
     7621 gacggctttt tggcgcaagg tatcgccgga gatgattttg tcggaggcgg tcgaagtgtg
     7681 cagcagcccc gaagtggcgc gcggacggct tttgccgacg acgctgaccg tttccaaatc
     7741 caccgattgc tcagtttcat gcgcttgggc gaggaggggt gtgttgatta aaagaattga
     7801 taaaacaatg ggtttgagtg tagtttgtgc cattttggtt tctcgtcgca tttcaaaagt
     7861 ttgttattat ataacattac attccttata tcataagatt ttgagaacac tcagagggca
     7921 taggcaaaag tttttcaaat gaaacggttg cggcatcggg cggtgtccat ttgtatccgc
     7981 cgtccttcgg gggcgcggtt gatgttgacg cagattccgc tgtgtttgcc cattatgttc
     8041 ggctgcggga taaccaaaat ttatgagtgc ataaaaacgg tacgttcccg aacggtcgaa
     8101 aaggtggcaa aatggcgtac ttgtcagaac gcgaggctct gcgccaggtt cacgagggtg
     8161 catcgggcac gctaagatat aagagggtat ggatgggggt atcggaaatg cagttaataa
     8221 caaacaaatt ataaatcaat aggttaataa caaaatgctt ttgtttatcg acaattacga
     8281 cagttttact tacaacatcg tccagtattt cgctgaattg gggcaggaag tcgccgtgcg
     8341 ccgcaacgat gatattacgt tggaagaaat cgaggcattg aatccgcaat atctcgttat
     8401 cggacccggt ccgtgttcgc ccaaagaagc ggggatttcc gtggcggcga tgcgccattt
     8461 tgccggccgg ctgccgatta tgggcgtgtg cctcgggcat cagacgatag gcgaggcgtt
     8521 cggcggcagg atagtccgcg ccaaaacgct gatgcacggt aaggtgtcgc ccgtgtccca
     8581 ttcgggcaag ggtatgttta aaggtttgcc caatccggtt acctgtacgc gttatcacag
     8641 cctcgttatc gatcgggata atttgcccga ttgtttggaa atcacggctt ggactgacga
     8701 cggcgagatt atgggcgtgc gccataagga atatgccgtc gagggcgtgc agttccaccc
     8761 cgaagccctc ttgaccgaac acggacatga tatgttgaac aattttttaa tcgaatttca
     8821 aaacttcaaa ccgcaaaaaa tctgacgcga tgccgtctga aggcttcaga cggcattttc
     8881 gtccgaatat tgaacggagg acaaaaaatg attacaccgc aacaggctat cgaacgatta
     8941 atcagcaata acgagttgtt ttacgatgaa atgaccgact tgatgcgtca gattatgaga
     9001 ggacaggttc tgccggagca gatagcggcc attttgacag gattgcgtat caaggttgaa
     9061 accgtttccg aaattaccgc agctgcagcc gtcatgcgcg agtttgcgac aaaagtgccg
     9121 ctggagaatg cagaggggct ggtcgatatc gtcggtacgg gcggggatgg tgccaaaacc
     9181 ttcaatattt cgacgacctc gatgtttgtt gccgcagcgg caggcgcgaa ggttgccaaa
     9241 cacggcgggc gttccgtttc atcttccagc ggcgcggcgg acgtggtgga gcagatgggc
     9301 gcaaacctca acctgactcc cgaacagatt gctcaaagta tcagccagac cggtataggg
     9361 tttatgttcg cccccaatca ccacagtgcc atgcgccatg tcgccccggt acgccgttcg
     9421 ctcggtttcc gaagcatttt caacatattg ggtccgttga ccaatcctgc gggcgcgccg
     9481 aaccaacttt tgggcgtgtt ccacaccgat ttgtgcggca ttttgtcgcg ggtcttgcaa
     9541 caacttggtt caaaacacgt tttggtcgtt tgcggggagg gcggcttgga tgaaattaca
     9601 ctgacgggca aaacgcgcgt tgccgaactc aaagacggaa aaatcagcga atacgacatc
     9661 cgcccagaag atttcggtat cgaaacccgc cgcaatttgg atgaaatcaa agttgccaat
     9721 actcaggaat ctttgttgaa aatgaatgag gtgctggatg ggaaagaagg ggctgcgcgc
     9781 gatatcgtat tgcttaatac cgccgccgcc ctatatgccg gaaatgtcgc cgcttcgctt
     9841 tcagacggca tatctgccgc acgggaagcc atcgattcag gtagggcaaa atcgaaaaaa
     9901 gaggagtttg tcggttttca accacaacaa agatgccatt ttcttggaaa gatggagctt
     9961 gggtgatgcc gccatgatta tggaactttt gtggcaaaac ataagcactt cacgaagaga
    10021 acttaccaaa ctgtttttat ataaaaactt ggggctgtac tagataacca gaccaaattc
    10081 ccattaacta attgtcttaa aatctgaatt tgagattcta tttaaaatgc cattggcatt
    10141 tctttaaatg cagccccaaa tgctctttgg gaatgccgtt aaacttacgt aaatggctaa
    10201 attcactaat atcaagcaca tcataactac gaaaggtatc cgtgtataca atgccatcag
    10261 gcttaacttt ctttcggata attggcaaca atgtcgctga ttgcgcatta ggaacaacga
    10321 cggta
//
LOCUS       DAXISH010000066         9676 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.066, whole genome shotgun sequence.
ACCESSION   DAXISH010000066 DAXISH010000000
VERSION     DAXISH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9676
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.066"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            235..345
                     /locus_tag="ACFOV4_001768"
                     /pseudo
     CDS             235..345
                     /locus_tag="ACFOV4_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            596..2053
                     /locus_tag="ACFOV4_001769"
     CDS             596..2053
                     /locus_tag="ACFOV4_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015333 - peptide:proton symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide:H+ symporter"
                     /protein_id="HFC7619726.1"
                     /translation="MSRHPAPTGEKTFFGHPFQLSTLFHIELWERFSFYGMQGILLIY
                     LYYTADKGGLGIDKTLAGGIVGAYSGSVYLSTILGAWFADRVWGAEKTLFLSGIVVML
                     GHIVLAAAPGLYGLLIGLIFIALGSGGVKSTASSMVGALYEQDEMRPLRDAGFSIFYI
                     AINIGGFLGPLLTGLLQENIGFHYGFGAAAVGMAFGLWRYSLGRKNLPHPIVPHPLSK
                     GQGKTAAAVGIALIAALATAIKTGLVNLDNFSGILLSTVILAVIAYFARLLTNPRVSS
                     DNKRHIIAYIPLFLTICMFWAVWFQIYTVATVYFDETVNRTIGSFTVPVAWKDSMQSL
                     WVILFSGLMAAMWTKMGRKQPKTPLKFAMAVFVTGASFLGFVPFISAGTPMPIAVFAL
                     IVLAITIGELMISPIALSISTKIAPPLFKTQMVALNFLAFSLGFTLGGVLFEKCYQAG
                     DEIGFYRLLFYIGAATGFLLLLLVPKLNKMLEGTD"
     gene            complement(2525..2884)
                     /gene="rnpB"
                     /locus_tag="ACFOV4_001770"
     ncRNA           complement(2525..2884)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACFOV4_001770"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(2963..4066)
                     /gene="prfB"
                     /locus_tag="ACFOV4_001771"
     CDS             complement(2963..4066)
                     /gene="prfB"
                     /locus_tag="ACFOV4_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFC7619727.1"
                     /translation="MEAEVINQLNNTLNDLEKRSEDIRVYMDYQGKKDRLEEVVGLSE
                     DPELWNDPKRAQEIGKERKILEGIVLTLDNIASGIEDNRMLIEMTVEENDEEGFAAVQ
                     EDVAGLEKQMADLEFKRMFNQPADPNNCFIDITAGAGGTEAEDWAGMLFRMYSRYAER
                     KGFKIEILEEDDGEIAGINRATIRVEGEYAYGLLRTETGVHRLVRYSPFDSNNKRHTS
                     FASVFVYPEIDDSIEIEINPADLRIDTYRASGAGGQHINKTDSAVRITHEPTGIVVQC
                     QNDRSQHANKAAAMEMLKSKLYELEMRKRNEEKQALEEGKSDVGWGSQIRSYVLDSSR
                     IKDLRTGYEVGNTKAVLDGDLDGFIEASLKQGV"
     gene            complement(4169..5062)
                     /locus_tag="ACFOV4_001772"
     CDS             complement(4169..5062)
                     /locus_tag="ACFOV4_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFC7619728.1"
                     /translation="MVTFSKIRPLLAIAAAALLAACGTAGNNAARKPVQTAKPAAVVG
                     LALGGGASKGFAHVGIIKVLKENGIPVKVVTGTSAGSIVGSLFASGMSPDRLELEAEI
                     LGKTDLVDLTLSTSGFIKGEKLQNYINRKVGGRQIQQFPIKFAAVATDFETGKAVAFN
                     QGNAGQAVRASAAIPNVFQPVIIGRHTYVDGGLSQPVPVSAARRQGANFVIAVDISAR
                     PGKNISQGFFSYLDQTLNVMSVSALQNELGQADVVIKPQVLDLGAVGGFDQKKRAIRL
                     GEEAARAALPEIKRKLAAYRY"
     gene            5404..5853
                     /locus_tag="ACFOV4_001773"
     CDS             5404..5853
                     /locus_tag="ACFOV4_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HFC7619729.1"
                     /translation="MKIGTTWQTASAMLVLRLFAAYEFLESGLQKWNGENWFSEINDQ
                     FPFPFNLLPDALNWNLAMYAELLLPVLLLLGLATRLSALGLMVVTAVAWAAVHAGSGY
                     NVCDNGYKMALIYIVVLIPLLFQGAGGWSLDTLLKKRFCPQCRLKQD"
     gene            5927..6235
                     /locus_tag="ACFOV4_001774"
     CDS             5927..6235
                     /locus_tag="ACFOV4_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619730.1"
                     /translation="MNKNIAAALAGALSLSLAAGAVAANKPASNATGVHKSAHGSCGA
                     SKSAEGSCGAAGSKAGEGKCGEGKCGATVKKTHKHTKAPKAKAKSAEGKCGEGKCGSK
                     "
     gene            6351..7193
                     /locus_tag="ACFOV4_001775"
     CDS             6351..7193
                     /locus_tag="ACFOV4_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF692 domain-containing protein"
                     /protein_id="HFC7619731.1"
                     /translation="MIQHAGLGYRRDLAEDFLSLSENSPICFIEAAPENWLKMGGWAR
                     KQFDRVAERLPLALHGLSMSLGGQAPLDTDLIDGIKEMMRRYDCTFFSDHLSYCHDGG
                     HLYDLLPLPFTEEMVHHTARRIREVQDRLGCRIAVENTSYYLHSPLAEMNEVEFLNAV
                     AREADCGIHLDVNNIYVNAVNHGLLSPEAFLKNVDADRVCYIHIAGHDVETPELLIDT
                     HGAAVLPTVWDLLELAYAKLPTIPPTLLERDFNFPPFAELEAEVAKIADYQTRAGKEY
                     RRAA"
     gene            7183..7929
                     /locus_tag="ACFOV4_001776"
     CDS             7183..7929
                     /locus_tag="ACFOV4_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2063 domain-containing protein"
                     /protein_id="HFC7619732.1"
                     /translation="MQPETSAQYQHRFAQAIRGGEAADGLPQDRLNVYIRLIRNNIHS
                     FIDRCYTETRQYFDSEEWSRLKEGFVRDAHAQTPYFQEIPGEFLQYCQSLPLSDGILA
                     LMDFEYTQLLAEVAQIPDIPDIHYSNDSKYTPSPAAFIRQYRYDVTDDLHEAETALLI
                     WRNAEDDVMYQTLDGFDMMLLEIMGSSALSFDTLAQTLVEFMPEDDNWKNILLGKWSG
                     WTEQRIIIPSLSAISENMEGNSPGQNHLST"
     gene            7951..8538
                     /locus_tag="ACFOV4_001777"
     CDS             7951..8538
                     /locus_tag="ACFOV4_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFC7619733.1"
                     /translation="MPLPDLTDAELIESRKLLLHFARLQLPDHPDLAEDLVQETLLSA
                     YSAGDSFQGRALVNSWLFAILKNKIIDALRQIGRQRKVFTTLDDELLDEAFESHFSQN
                     GHWTPEGQPQHWNTPEKSLNNNEFQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQ
                     MCGISTSNYHTIMHRARESLRQCLQIKWFNQENPK"
     gene            8544..8723
                     /locus_tag="ACFOV4_001778"
     CDS             8544..8723
                     /locus_tag="ACFOV4_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003692066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HFC7619734.1"
                     /translation="MKKCRDIALLLSKHQDRETTPGEKISIYTHLLFCPHCREYKRQL
                     QTIKISLAKTTRTSK"
     gene            8955..9395
                     /locus_tag="ACFOV4_001779"
     CDS             8955..9395
                     /locus_tag="ACFOV4_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-adhesin E family protein"
                     /protein_id="HFC7619735.1"
                     /translation="MIKETLMRPIFLSFVLLPILITACSTPDKSARWENIGTISNGNI
                     HTYINKDSVRKNGNLMIFQDKKVVTNLKQERFANTPAYKTAIAEWEIHCNNKTYRLSS
                     LQLFDTKNTEISTQNYTASSLRPMSILSGTLTEKQYETVCGKKL"
BASE COUNT         2440 a         2617 c         2203 g         2416 t
ORIGIN      
        1 cgcgggaatg acggctgcag atgcccgacg gtctttatag cggattaaca aaaatcagga
       61 caaggcgacg aagccgcaga cagtacaaat agtacgaaac cgactcactt ggtgcttcag
      121 caccttagag aatcgttctc tttgagctaa ggcgaggcaa cgccgtaccg gtttttgtta
      181 atccgctata atgcgccctt cggcgtggcg gatatataag gaagtgattt tccatctaag
      241 tatagtggat taaatttaaa tcaggacaag gcgacgaagc cgcagacagt acaaatagta
      301 cggcaaggcg aggcaacgcc gtactggttt aaatttaatc cactataaaa aaccgcccta
      361 tcggataagc ccttaacaga aaaggcttta cccgcgccgt atcggaacac atcctctaaa
      421 atacaatccg ttgaattgaa aaaaatataa aaacatccgc ccgcgaaaaa cggcagcgcg
      481 tcgtttgaca aagaatgaaa atatcggtta aaaaccgatt ttcatacaaa aaacaccgct
      541 gccgtccgca tccgtttcag acggtattga gagaaaatct tttaggagaa cctttatgtc
      601 ccggcatccc gcccccaccg gagaaaaaac attcttcggc caccccttcc agctttccac
      661 cctcttccat atcgaattgt gggaacgttt ttcattttac ggaatgcagg gcatcctgct
      721 gatttacctc tactacaccg ccgacaaagg cggcttgggc atagacaaaa ccctcgccgg
      781 cggcattgtc ggcgcataca gcggcagcgt gtacctgtcc accattttgg gggcgtggtt
      841 tgccgaccga gtatggggtg cggaaaaaac cctcttcctc tcgggcatcg tcgtgatgct
      901 cggacacatc gtccttgccg ccgccccggg cctgtacggc cttttaatcg ggctgatatt
      961 catcgcattg ggcagcggcg gcgtgaaatc tacggccagt tctatggtgg gcgcattata
     1021 cgaacaggac gaaatgcggc cgctgcgcga tgcgggattt tccattttct acatcgccat
     1081 caatatcggc ggcttcctag gcccgctgct gaccggcctg ctgcaggaaa acatcggttt
     1141 ccattatggt ttcggcgcgg cggcggtcgg tatggcattc ggcttgtggc gttattcctt
     1201 gggacgtaaa aacctgcccc atcccatcgt cccccatccg ctttcaaaag gacagggcaa
     1261 aactgcggcc gccgtcggca ttgctctcat cgccgcactt gcaaccgcca tcaaaaccgg
     1321 gcttgtcaac ctcgacaatt tctccggcat cctcttatct accgtcatcc ttgccgtcat
     1381 tgcctatttt gcccgcctgc tgactaatcc ccgcgtcagt tccgacaaca aacggcacat
     1441 catcgcctac atcccgcttt tcctgaccat ctgtatgttt tgggccgtct ggtttcagat
     1501 ttacaccgta gcaaccgtct atttcgacga aaccgtcaac cgcaccatcg gttcgtttac
     1561 cgtgcccgtc gcctggaaag attccatgca aagcctgtgg gtcatcctgt tttccggact
     1621 gatggcggca atgtggacaa aaatggggcg caaacagccc aaaaccccgc tgaaattcgc
     1681 tatggcggta tttgttaccg gcgcgtcgtt tttgggattc gtccccttta tttccgccgg
     1741 cacgccgatg cctattgcgg ttttcgcact gattgtcctt gccatcacga taggcgaact
     1801 gatgatttcc ccgattgcgc tgtccatctc caccaaaatc gcaccgcctt tattcaaaac
     1861 ccaaatggtc gcccttaatt tccttgcctt ttcattaggc ttcactttgg gcggcgtatt
     1921 gtttgaaaaa tgctatcagg cgggcgacga aatcggcttc tatcggctgc tgttctacat
     1981 cggcgcagcc acaggcttcc tgctgctcct gctcgtcccc aaattgaaca aaatgctcga
     2041 aggcacagac taagtcccgc cccgatgccg tctgaaccct tcagacggca tttttccgca
     2101 taatgaaacc aaaccgtttc cacccgacag gacaggctcc ccccaaccgg aaggcagcct
     2161 gccgattgtc atttaaatat ctgactgatt ccgtctgttt gcaagggaaa tagccgttta
     2221 tttccgcttg ggcggaaacc ggttctattg agtaaaaggc attttatccg actaaattag
     2281 tgctgcatca acggaatata tagtggatta acaaaaatca ggacaaggcg acgaagccgc
     2341 agacagtaca aacagtacgg aaccgattca cttggtgctt cagcacctta gagaatcgtt
     2401 ctctttgagc taaggcgagg caacgccgta ccggtttttg ttaatccact ataaaaacac
     2461 aacctaaata aaaatgccgt ctgaaccata tttcaggttt cagacggcat ttgcgtgtcg
     2521 gatgcacacc ggacgggcgg taagccgggt tctgtctcgg acagtcattc ctctaggcat
     2581 accgttaccg gtatgctcaa gcaacctacc cgaacgctcg gcgggcagcg tcattgcgtt
     2641 ctgtttggtc ttgctccgaa tggggtttgg cctgccgcat attgttacca aatgcgcggt
     2701 gcgcccttac cgcacctttt cacccttgcc tgtgctgcca aagcagccat cggcggtttt
     2761 gctttctgtt ccactttccg tcgcgttacc gcgcccggcc gttaaccggc attctaccct
     2821 gcggagcccg gactttcctc cccgtatgcc ttacgcgata cgcggcgact gtctgcccgt
     2881 cccgtgtgcg gcgcggatta taacacgaaa cgcaaaaatg ccgtctgaaa cggtacaggt
     2941 ttcagacggc atacagccta aactacacgc cctgtttcag gctggcttcg ataaagccgt
     3001 ccaaatcgcc atccaatacg gctttggtgt tgccgacttc gtagcctgta cgcaagtctt
     3061 tgatacgtga ggaatccaaa acatacgaac ggatttggct gccccaacct acatcggatt
     3121 taccttcttc caacgcctgt ttctcttcat tgcgtttgcg catttccaat tcatacagtt
     3181 tggacttcaa catttccatc gcggcggctt tgttggcgtg ttgcgaacgg tcgttttgac
     3241 attgcaccac aatccccgtc ggctcgtggg taatgcgcac ggcggagtcg gttttattga
     3301 tgtgctgacc gcccgcaccc gatgcgcgat aggtgtcgat gcgcaaatcg gcggggttga
     3361 tttcgatttc gatggaatcg tcgatttcgg gatagacgaa cacggaggca aacgaggtat
     3421 ggcgtttgtt gttcgagtca aacggagagt aacgcaccaa gcggtgaaca cctgtttccg
     3481 tgcgcagcaa gccgtaggca tattcgcctt ccactcggat agtcgcgcgg ttgatgcccg
     3541 cgatttcgcc gtcgtcttct tcgaggattt cgattttgaa gcctttgcgc tcggcgtagc
     3601 ggctgtacat gcggaacagc atacccgccc agtcttccgc ttccgtaccg cctgcgcctg
     3661 cggtaatgtc gataaagcag ttgttcggat cggcgggctg gttgaacatc cgtttgaact
     3721 ccaaatccgc catctgtttt tccagccccg ccacatcttc ctgcacggcg gcaaaacctt
     3781 cttcgtcgtt ttcttcgacg gtcatttcaa tcagcatgcg gttgtcttcg atgcccgaag
     3841 cgatgttgtc gagcgtcaac acgatgcctt cgaggatttt gcgctctttg ccgatttctt
     3901 gggcgcgttt cgggtcgttc caaagttcgg ggtcttcgga aagaccgaca acttcttcca
     3961 atcggtcttt cttaccctga taatccatat aaactcggat gtcttcgctg cgcttttcca
     4021 aatcattcag ggtattgttg agctggttga ttacttcggc ttccatgatt cttttgttct
     4081 ttcaaaattt taggggcgta ttgtacggga ttcgggtatt tttttctatg gataaagcct
     4141 tctggaaaca cgttcggacg gcatagcgtc aataacggta tgccgccagt ttgcgtttga
     4201 tttcaggcaa tgcggcacgt gctgcctcct cacccaaccg gatggcgcgt tttttctgat
     4261 cgaatccgcc gactgcaccc aaatccaaaa cctgcggttt gataaccaca tccgcctgcc
     4321 ccaactcatt ttgcaacgcg gaaacgctca ttacgttcag cgtctgatcg agataagaga
     4381 agaagccttg gctgatgttt ttgcccggac gggcggaaat atcgacggca atcacgaaat
     4441 tcgccccctg ccgccgggcg gcactgacgg gcacgggctg cgacagaccg ccgtcaacat
     4501 atgtatgcct gccgatgata acgggttgga acacattggg aatggcggcg gaagcgcgca
     4561 cagcctgccc ggcattccct tgattgaaag cgacggcctt gccggtttca aaatcagtag
     4621 caacagcggc aaatttgatg ggaaactgct gaatctgcct gccgccgact tttcggttga
     4681 tgtaattttg cagcttttcg cctttgataa aaccactggt ggacaaggtt aaatcgacta
     4741 aatcggtttt gcctaaaatt tcggcttcca attcgaggcg gtcgggcgac atacccgatg
     4801 caaaaaggct gccgactatc gaacctgccg atgtgccggt aaccaccttc acaggaatac
     4861 cgttttcttt caaaacctta ataataccta catgggcaaa tcctttagat gcgccgccac
     4921 cgagtgccaa accgaccact gcggcgggtt tggcggtttg caccggcttg cgggcagcat
     4981 tatttcccgc cgtgccgcag gcggcaagca acgcggcggc ggcgattgcc aaaagcggtc
     5041 tgatttttga aaacgttacc atattttcca ttcctttata tatcgcaccc cgtcaaaaag
     5101 agggattgct tttcttaaca accccctttg acagccaagc aaatgggggc tttgttaagt
     5161 catcatcaaa attaatattt ctttttttcc tttacggaaa ttatatttga aggcatacta
     5221 tccaaggcgg gaattatctc acaacaccgc cgttatccaa atatcccgcc tttttccttt
     5281 cctttccatc aaaatacttt ctttttatat tcattaactt gttaaatcat tggctgccgg
     5341 gtgtcagttt ttccgacaaa atccgtctaa tggggtatca acagaaccaa aacaggaaca
     5401 cttatgaaaa tcggaacaac ttggcagacg gcatccgcta tgctggtttt gcgtctgttt
     5461 gccgcatatg aatttttgga atcgggtttg caaaaatgga acggggagaa ttggttttcc
     5521 gaaatcaacg atcagtttcc attcccgttc aacttgctgc cggacgcgtt aaactggaat
     5581 ctcgccatgt atgcggagct tttactgccc gtactgttgc ttttgggttt ggcaacgcgt
     5641 ctgtcggcat tagggctgat ggtcgttacc gccgtcgctt gggctgcggt tcacgccggt
     5701 tcgggttaca atgtctgcga caacggttat aaaatggctt taatttatat cgtggtatta
     5761 atcccgctgc ttttccaggg tgcgggcgga tggtcgctgg atacgctgct gaaaaaacgg
     5821 ttttgccccc aatgccgtct gaagcaagat tgattcagtc gtggaatctg actttaaaca
     5881 ttccaacctt atctcgttaa cttgatattc tgaaaaggaa atagaaatga acaaaaacat
     5941 tgctgccgca ctcgccggtg ctttatccct gtctttggcc gccggtgcag ttgctgccaa
     6001 caaaccggca agcaacgcaa caggcgttca taaatccgcc catggctctt gcggcgcgtc
     6061 caaatctgcc gaaggttcgt gcggcgcggc tggttctaaa gcaggcgaag gcaaatgcgg
     6121 cgagggcaaa tgcggtgcga ccgtaaaaaa aacccacaaa cacaccaaag cacctaaagc
     6181 caaggccaaa tctgccgaag gcaaatgcgg cgaaggcaaa tgcggttcta aataatcccc
     6241 ccccttcaaa ccaagccgcg tttttcagta aaatgcggct tttttaacgg caaacaaaga
     6301 ttttttaaca agcacatcat tcttttgtgc catccgaacc gggtaaaaat atgattcaac
     6361 acgcaggctt gggctaccgc cgcgacttgg cggaagactt tctctcgctt tccgaaaaca
     6421 gcccgatatg ctttatcgaa gccgcaccgg aaaactggct gaaaatgggc ggctgggcgc
     6481 gcaaacagtt tgaccgtgtg gcggaacggc tgccgctggc gttgcacgga ttgtctatgt
     6541 cgctgggcgg gcaagcaccg ctggatactg atttgataga cggcatcaaa gaaatgatgc
     6601 gccgttacga ttgcacgttt ttctccgacc atttgagcta ctgccacgac ggcggtcatc
     6661 tttacgattt gttgccgctg cccttcaccg aggaaatggt gcatcatacg gcgcggcgta
     6721 tccgtgaagt gcaagaccgt ttgggctgcc gcatcgccgt ggaaaacacg tcctactatc
     6781 tgcattcccc gcttgccgag atgaacgagg tcgagttcct caacgccgtc gcacgtgagg
     6841 ccgattgcgg cattcatctg gatgtgaaca atatctacgt caacgccgtc aatcacggcc
     6901 tgttgtcgcc ggaggctttt ttgaaaaacg ttgacgcaga tcgcgtgtgc tatatccata
     6961 ttgccggaca tgacgtggaa acgccggaat tgttgattga tacacatggc gcggcagttt
     7021 tgccgactgt ttgggacttg ctcgaacttg cctatgccaa gctgccgacg attccgccca
     7081 ccctgttgga acgcgatttt aatttcccgc cttttgccga actcgaagcc gaagtcgcca
     7141 aaatcgccga ttatcaaacg cgtgccggaa aggaataccg ccgtgcagcc tgaaacctcc
     7201 gcccaatacc agcaccgttt cgcccaagcc atacgcgggg gcgaagccgc agacggtctg
     7261 ccgcaagacc gactgaacgt ctatatccgc ctgatacgca acaatatcca cagctttatc
     7321 gaccgctgct ataccgaaac gcggcaatac tttgacagcg aagaatggag ccgtctgaaa
     7381 gaaggtttcg tccgcgacgc gcacgcccaa acgccctatt ttcaagaaat ccccggcgag
     7441 ttcctacaat attgccaaag cctgccgctt tcagacggca ttttggcact gatggatttt
     7501 gaatataccc aattgctggc agaagttgct caaattccgg atattcccga cattcattat
     7561 tcaaatgaca gcaaatacac accctcccct gcggccttta tccggcaata tcgatatgat
     7621 gttaccgatg atttgcatga agcggaaaca gccttgttaa tatggcgaaa cgccgaagat
     7681 gatgtgatgt accaaacatt ggacggcttc gatatgatgc tgctagaaat aatgggttcc
     7741 tccgcgcttt cgtttgacac cctcgcccaa acccttgtcg aatttatgcc tgaggacgat
     7801 aattggaaaa atattttgct tgggaaatgg tcaggctgga ctgaacaaag gattatcatc
     7861 ccctccttgt ccgccatatc cgaaaatatg gaaggcaatt ccccgggcca aaaccatcta
     7921 tccacataaa attaccttgt tcccgatact atgccgctac ccgacctgac cgatgccgaa
     7981 ttaatagagt cgcgtaaact gcttctgcat tttgcgcggc ttcagttgcc cgaccaccct
     8041 gatttggctg aagatttagt gcaggaaaca ttgctgtccg catacagcgc aggcgacagt
     8101 tttcaaggca gggcacttgt caacagctgg ctttttgcca tattgaaaaa caaaattatt
     8161 gacgcattac gtcaaatcgg aaggcagagg aaagtcttta ccacactgga tgacgagcta
     8221 ctggatgaag catttgaaag ccatttttcc caaaacgggc attggacgcc ggaagggcag
     8281 ccgcaacatt ggaacactcc ggaaaaatca ttaaacaaca acgaattcca aaaaattctg
     8341 caaagctgcc tatacaactt gcctgaaaac accgcacggg tatttaccct gaaggaaata
     8401 ctcggttttt catccgacga aatacaacaa atgtgcggta tcagcacgtc caactaccac
     8461 accattatgc accgcgcccg agaatcattg cgccaatgcc tgcaaatcaa atggttcaac
     8521 caagaaaacc cgaagtaaac gttatgaaaa aatgccgcga tatcgccctg cttctttcca
     8581 aacatcagga ccgggaaacc accccgggcg agaagatttc catatacaca cacctgctgt
     8641 tctgcccaca ttgccgagaa tataaaagac agcttcaaac catcaaaata tcactggcaa
     8701 aaacaaccag aacttcaaaa taaatgccgt ctgaaaaggc ttcagacggc ataagctgac
     8761 ggaaaaaaat caaaccgatt tactgttatc ggcagttcat ccataataca cgcttcaaaa
     8821 gcagcatatt cctccatacg gaatatataa atacgcaaaa cacgaaggct gcatcaattt
     8881 gctttatttg ccttatttca cagacggcgc tacccctccc gcccaacccg ttctttctga
     8941 atgagcagat ttcaatgatt aaggaaaccc taatgcgccc aatcttccta tctttcgttt
     9001 tactccctat tttgataacc gcctgcagca caccggacaa gtctgcccga tgggaaaata
     9061 tcggcacaat ctcaaacggc aatattcata catatatcaa taaagacagc gtgagaaaaa
     9121 acggaaatct gatgattttc caagataaaa aagttgttac caatctaaaa caagaacgtt
     9181 ttgccaacac ccccgcatac aagactgcca ttgccgagtg ggaaatccac tgcaacaaca
     9241 aaacataccg cttaagttcg ctacagttgt ttgatacaaa aaacacggaa atttccacac
     9301 aaaactacac agcctcttcc ctccgcccga tgagcatcct gtccgggaca ttaaccgaaa
     9361 aacaatatga aaccgtatgc ggaaaaaaac tctgattgca acttatacac aaacttaccc
     9421 acaaacctta tcataaaaat gccgtctgaa atactgaaat atcagcattt cggacggcat
     9481 tttgccattt ctccgaaaag ttatcctcga agttatccac attatttttt taaaccagct
     9541 tccatccgaa atataaacct gctatacaat ttcattatca aaacgtaaat tgttccattg
     9601 atacacaaaa ctgcttaccc ccataatttt gataaagcat ttcttacatt cccggctccg
     9661 tcccgtaatc aacaca
//
LOCUS       DAXISH010000067         9472 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.067, whole genome shotgun sequence.
ACCESSION   DAXISH010000067 DAXISH010000000
VERSION     DAXISH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.067"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            54..1364
                     /gene="argA"
                     /locus_tag="ACFOV4_001780"
     CDS             54..1364
                     /gene="argA"
                     /locus_tag="ACFOV4_001780"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004042 - acetyl-CoA:L-glutamate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HFC7619736.1"
                     /translation="MIVPDLFVAHFREAAPYIRQMRGKTLVAGIDDRLLEGDTLNKLA
                     ADIGLLSQLGIRLVLIHGARHFLDRHAATQGRTPHYCRGLRVTDETSLEQAQQFAGTV
                     RSRFEAALCGSVSGFARAPSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRF
                     QLDAGNIVWLPPLGHSYSGKTFHLDMLQTAASVAVSLQAEKLVYLTLSDGISRPDGTL
                     AVTLSAQEAQSLAEHAGGETRRLISSAVAALEGGVHRVQILNGAADGSLLQELFTRNG
                     IGTSIAKEAFVSIRQAHSGDIPHIAALIRPLEEQGILLHRSREYLENHISEFSILEHD
                     GNLYGCATLKTFTEADCGEIACLAVSPQAQDGGYGERLLAHIIDKARGIGISRLFALS
                     TNTGEWFAERGFQTASEDELPETRRKDYRSNGRNSHILVRRLHR"
     gene            1563..3578
                     /locus_tag="ACFOV4_001781"
     CDS             1563..3578
                     /locus_tag="ACFOV4_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family protein"
                     /protein_id="HFC7619737.1"
                     /translation="MKSYPDPYRHFENLDSAETQNFAAEANAETRARFLNNDKARALS
                     DGILAQMQDTRQIPFCQEHRARMYHFHQDAEYPKGVYRVCAAATYRSGYPEWKILFSV
                     ADFDELLGDDVYLGGVSHLVEKPDRALLTLSKSGGDTAYTLEVDLEAGELVEGGFHFP
                     AGKNHVSWRDENSVWVCPAWDERQLTESGYPREVWLVERGKSFEESLPVYQIGEDGMM
                     VNAWRYLDPQGSPIDLIEASDGFYTKTYLQVSAEGEAKPLNLPADCDVVGYLAGHLLL
                     TLRKDWHRANQSYPSGALVAVKLNRGEIGAAQLLFAPDETQALESVETTKRFVVASLL
                     ENVQGRLKAWRFTDGKWQEAELPRLPSGALEMTDQPWGGDVVYLAASDFTTPLTLFAL
                     DLNVMELTVMRRQPQQFDSDGINVQQFWTTSADGERIPYFHVGKNAAPDTPTLVYAYG
                     GFGIPELPHYLGSVGKYWLEEGNAFVLANIRGGGEFGPRWHQAAQGISKHKSVDDLLA
                     VVRDLSERGISSPQHIGLQGGSNGGLITAAAFVREPQSIGALVCEVPLTDMIRYPLLS
                     AGASWTDEYGNPQKYEVCKCRLGELSPYHNLSDGIDYPPALITTSLSDDRVHPAHALK
                     FYAKLRETSAQSWLYSPDGGGHTGNGTQRESADELACVLLFLKEFLG"
     gene            complement(3692..4648)
                     /locus_tag="ACFOV4_001782"
     CDS             complement(3692..4648)
                     /locus_tag="ACFOV4_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC7619738.1"
                     /translation="MNTAAIYRQYQTYVRSDKSGWALDGCSDSALIAQAKQPGLHLEM
                     CINRFDSGITLSRMRGGGTGAFPTEIHNFSHNCALFVMVSGQNRLQMGGREYRPSAGE
                     IWLVRGELADVSETLLPDNSGMCALHLDFSLEKLRRWHDEGLLDERLFSPQTIGRFAL
                     QRLAQNAAALTAAACPLLQRPFESDGFGLLADEAAALELSARLLRFTFRRHDNGYRRR
                     RIDEAADILQHEFARPLTIAEIARRVGLNECYLKRYFKAQTGETVAGCLRRLRLEHAL
                     ALIESGSTVQAAMHFCGYRHAGRFNEAFRRHYGFLPSDVKKC"
     gene            4884..5849
                     /locus_tag="ACFOV4_001783"
     CDS             4884..5849
                     /locus_tag="ACFOV4_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7619739.1"
                     /translation="MKPRFYWAACAVLLTACSPEPAAEKTVSAASASAATLTVPTARG
                     DAVVPKNPERVAVYDWAALDTLTELGVNVGATTAPVRVDYLQPAFDKAATVGTLFEPD
                     YEALHRYNPQLVITGGPGAEAYEQLAKNATTIDLTVDNGNIRTSGEKQMETLARIFGK
                     EARAAELKAQIDALFAQTREAAKGKGRGLVLSVTGNKVSAFGTQSRLASWIHGDIGLP
                     PVDESLRNEGHGQPVSFEYIKEKNPDWIFIIDRTAAIGQEGPAAVEVLDNALVRGTNA
                     WKRKQIIVMPAANYIVAGGSRQLIQAAEQLKEAFEKAEPVAAGKE"
     gene            6860..7183
                     /locus_tag="ACFOV4_001784"
     CDS             6860..7183
                     /locus_tag="ACFOV4_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003775941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFC7619740.1"
                     /translation="MQNETINPKQHLAAIKEYWQPEIINRHGFQFRLVKLLGDYGWHT
                     HGYSDKVLFAVEGDMAVDFADGGSMTIREGEMAVVPKSVSHRPRSENGCSVVLIELSD
                     PSEAV"
     gene            7297..>9472
                     /locus_tag="ACFOV4_001785"
     CDS             7297..>9472
                     /locus_tag="ACFOV4_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010950972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HFC7619741.1"
                     /translation="MTRFKYSLLFAALLPVYAQADVSVSDDPKPQESTELPTITVTAD
                     HTASSNDGYTVSGTHTPLGLPMTLREIPQSVSVITSQQMRDQNIKTLDRALLQATGTS
                     RQIYGSDRAGYNYLFARGSRIANYQINGIPVADALADTGNANTAAYERVEVVRGVAGL
                     LDGTGEPSATVNLVRKRPTRKPLFEVRAEAGNRKHFGLGADVSGSLNTEGTLRGRLVS
                     TFGRGDSWRQRERSRDAELYGILEYDIAPQTRVHAGMDYQQAKETADAPLSYAVYDSQ
                     GYATAFGPKDNPATNWANSRHRALNLFAGIEHRFNQDWKLKAEYDYTRSRFRQPYGVA
                     GVLSIDHNTAATDLIPGYWHADPRTHSASVSLIGKYRLFGREHDLIAGINGYKYASNK
                     YGERSIIPNAIPNAYEFSRTGAYPQPASFAQTIPQYGTRRQIGGYLATRFRAADNLSL
                     ILGGRYSRYRTGSYDSRTQGMTYVSANRFTPYTGIVFDLTGNLSLYGSYSSLFVPQSQ
                     KDEHGSYLKPVTGNNLEAGIKGEWLAGRLNASAAVYRARKNNLATAAGRDPSGNTYYR
                     AANQAKTHGWEIEVGGRITPEWQIQAGYSQSKTRDQDGSRLNPDSVPERSFKLFTAYH
                     FAPEAPSGWTIGAGVRWQSETHTDPATLRIPNPAAKARAADNSRQKAYAVADIMARYR
                     FNPRAELSLNVDNLFNKHYRTQPDRHSYGALRTVNAAFTYRFK"
BASE COUNT         2096 a         2947 c         2665 g         1764 t
ORIGIN      
        1 accctgtttg cccttatcgt cctcattatg cagctttcct acctcgtcat cctatgatcg
       61 tgcccgacct ctttgtcgcc cacttccgcg aagccgcccc ctacatccgc caaatgcgcg
      121 gcaaaacgct ggtcgccggc atagacgacc gcctgctcga aggtgatacc ttaaacaagc
      181 tcgccgccga catcgggctt ttgtcgcaac tgggcatcag gctcgtcctc atccacggcg
      241 cgcgccactt cctcgaccgc cacgccgcca cgcaaggccg cacgccgcat tattgccggg
      301 gcttgcgcgt taccgacgaa acctcgctcg aacaggcgca gcagtttgcc ggcaccgtcc
      361 gcagccgttt tgaagccgca ttgtgcggca gcgtttccgg gttcgcgcgc gcgccttccg
      421 tcccgctcgt atcgggcaac ttcctgaccg cccgtccgat aggtgtgatt gacggaaccg
      481 atatggaata cgcgggcgtt atccgcaaaa ccgacaccgc cgccctccgt ttccaactcg
      541 acgcgggcaa tatcgtctgg ctgccgccgc tcggacattc ctacagcggc aagaccttcc
      601 atctcgatat gcttcaaacc gccgcctccg tcgccgtctc gcttcaggcc gaaaaactcg
      661 tttacctgac cctttcagac ggcatttccc gccccgacgg cacgctcgcc gtaaccctct
      721 cggcacagga agcgcaatcg ctggcggaac acgccggcgg cgaaacgcga cggctgattt
      781 cgtccgccgt tgccgcgctc gaaggcggcg tgcatcgcgt ccaaatcctc aacggtgccg
      841 ccgacggcag cctgctgcaa gaactcttca ctcgcaacgg catcggcacg tccattgcca
      901 aagaagcctt cgtctccatc cggcaggcgc acagcggcga catcccgcac attgccgccc
      961 tcatccgccc gctggaagaa caaggcatcc tgctgcaccg cagccgcgaa tacctcgaaa
     1021 accacatttc cgaattttcc atcctcgaac acgacggcaa cctgtacggt tgcgccaccc
     1081 taaaaacctt taccgaagcc gattgcggcg aaatcgcctg ccttgccgtc tcgccgcagg
     1141 cacaggacgg cggctacggc gaacgcctgc ttgcccacat tatcgataag gcgcgcggca
     1201 taggcataag caggctgttc gcactgtcca caaataccgg cgaatggttt gccgaacgcg
     1261 gctttcagac ggcatcggaa gacgagttgc ccgaaacgcg gcgcaaagac taccgcagca
     1321 acggacggaa ctcgcatatt ctggtgcgtc gcctgcaccg ctgaccgcaa cggaaagccg
     1381 ccgcagaaat gccgtctgaa ccccgtttca gacggcattt ccccgattat atagtggatt
     1441 aacaaaaacc agtacggcgt tgcctcgcct tgccgtacta tttgtactgt ctgcggcttc
     1501 gtcgccttgt cctgattttt gttaatccac tataaagacc tgcccaaccc tcaaggaccc
     1561 cgatgaaatc ctaccccgac ccctaccgcc attttgaaaa cctcgattcc gccgaaacgc
     1621 aaaacttcgc tgctgaagcg aatgccgaaa cgcgcgcgcg ttttttaaac aacgacaagg
     1681 cgcgcgcgct ttcagacggc attttggcgc agatgcagga cacgcggcag attccgtttt
     1741 gtcaggaaca ccgcgcgcgg atgtaccatt tccatcagga cgcggagtat ccgaagggcg
     1801 tgtaccgcgt gtgtgcggcg gcgacgtatc gttccggcta tcccgagtgg aaaatcctgt
     1861 tttcagtggc ggatttcgac gagctgctcg gcgacgatgt gtatttgggc ggcgtgtcgc
     1921 acttggtgga aaagcccgac cgtgcgttgt taacactgag caaatcgggc ggcgatacgg
     1981 cgtacacgct ggaagtggat ttggaagcag gggagttggt agaaggcggt tttcactttc
     2041 cggcaggcaa aaaccatgtg tcgtggcgcg atgaaaacag cgtgtgggtg tgtccggcct
     2101 gggacgagcg gcagttgacc gaatcgggct atccgcgcga ggtgtggctg gtggaacgcg
     2161 gcaaaagttt cgaggaaagc ctgccggtgt accaaatcgg cgaagacggg atgatggtga
     2221 acgcgtggcg ttacctcgat ccgcagggtt cgccgattga tttgattgaa gcgtctgacg
     2281 gtttttacac caaaacctat ttgcaggtgt cggccgaagg cgaggcgaaa ccgttaaacc
     2341 tgcctgctga ttgcgatgtg gtcggctatc tggcggggca tcttttgctg acgctgcgca
     2401 aggactggca ccgcgcgaac caaagctatc cgagcggcgc gctggtagcg gtgaaactga
     2461 atcgcggcga aatcggggcg gcgcagcttt tgtttgcgcc tgatgaaacg caggcattgg
     2521 aaagcgtgga aacgaccaag cgttttgtcg tggcgagtct gctggaaaac gtacaaggcc
     2581 gtctgaaagc gtggcgtttt accgacggca aatggcagga agccgaactg ccgcgcctgc
     2641 cctcgggcgc gttggaaatg accgaccaac cgtggggtgg cgacgtggtt taccttgccg
     2701 ccagcgattt caccacgccg ctgacgctgt ttgcgctgga tttgaacgtg atggaactga
     2761 ccgtcatgcg ccgtcagccg cagcagttcg attcagacgg catcaacgtg cagcagtttt
     2821 ggacgacttc ggccgacggc gagcgtattc cttattttca cgtcggcaaa aacgccgccc
     2881 ccgacacgcc gactttggtt tatgcatacg gcggttttgg cattcccgag ttgccgcatt
     2941 atttgggcag cgtcggcaaa tattggctgg aagagggcaa tgcctttgtg ttggcaaaca
     3001 tccgcggcgg cggcgagttc ggcccgcgct ggcatcaggc ggcgcaggga atcagcaaac
     3061 acaaaagcgt cgacgatttg cttgccgtcg tgcgcgattt gtccgaacgc ggtatcagtt
     3121 cgccccaaca catcggcttg cagggcggca gcaacggcgg cctgattacc gccgccgcct
     3181 tcgtgcgcga accgcaaagc atcggcgcgc tggtgtgcga agtgccgctg accgatatga
     3241 tccgctatcc gctgctctcc gccggcgcaa gctggacgga cgaatacggc aacccgcaga
     3301 aatacgaagt ctgcaaatgc cggttgggcg aattgtcgcc gtatcacaat ctttcagacg
     3361 gcatcgatta tccgccagcg ctcattacca ccagcctcag cgacgaccgc gtccatcctg
     3421 cccacgcgct caagttctac gccaaactgc gcgaaacctc cgcgcaatct tggctctact
     3481 cacctgacgg cggcggccat accggcaacg gcacccaacg cgaatccgcc gacgaactcg
     3541 cctgcgtgtt gctgtttttg aaagagtttt tgggctaagg gcggggagcg gcactgccgc
     3601 cgcgaatgaa aaaaggtcgt ctgaaactgc tttttcagac gacctttttt aatggttgtt
     3661 tcaaatcaaa atatctatgc cgccggcccc atcagcactt cttcacatcc gaaggcaaaa
     3721 atccgtaatg ccgtctgaac gcttcgttga accgtcccgc gtggcggtag ccgcaaaagt
     3781 gcatggcggc ttggacggtg ctgccggatt cgatgagggc gagcgcgtgt tccagccgca
     3841 ggcggcgcag gcatccggcg acggtttcgc cggtttgcgc tttgaaatag cgtttcaggt
     3901 agcattcgtt cagtccgacg cggcgggcga tttcggcgat ggtcagcgga cgggcgaatt
     3961 cgtgttgcag gatgtcggcg gcttcgtcta tgcgccgacg gcggtaaccg ttgtcgtggc
     4021 ggcggaaggt gaagcgcaat aatcgggcgg agagttccag cgcggcggct tcgtcggcaa
     4081 gcaggccgaa gccgtccgat tcgaacgggc gttgcagcag tgggcaggcc gccgccgtca
     4141 gtgccgccgc gttttgcgcc agccgttgca gggcgaatcg gcctatcgtt tgcggcgaaa
     4201 acaggcgttc gtccagcaag ccttcgtcgt gccagcggcg cagtttttcc agcgaaaaat
     4261 ccaaatgcag cgcgcacatg ccgctgttgt cgggcagcag ggtttcggat acgtccgcca
     4321 actcgccgcg taccagccag atttcgccgg cagacgggcg gtattccctg ccgcccattt
     4381 gtaaccggtt ctgccccgac accatgacga acaaggcgca gttgtggctg aaattgtgga
     4441 tttcggtggg aaacgcgccc gttccgccgc cgcgcatccg cgacaaggtg atgcccgaat
     4501 cgaagcggtt gatgcacatt tccagatgca aaccgggctg ttttgcctgc gcaatgagcg
     4561 cgctgtcgga acagccgtcc aacgcccagc cggatttatc ggagcggaca taggtttggt
     4621 actggcggta gatggcggcg gtgttcatga ttggatagga acgagttgtc taacaaatga
     4681 attaaatagg aattattacc aataatcaag cgcagggatt ggttgaaacg gaaaaggtcg
     4741 tctgaaaggg tgtttcagac gaccttttcc gtatcgggaa tttgttttgc cgtatcggga
     4801 attttgcgtt ttgcggcgtg gtttctgcag gttgtttgct taataataaa cattcttatt
     4861 cgtatgcaaa ggaaccgcac accgtgaaac cgcgttttta ttgggcagcc tgcgccgtcc
     4921 tgctgaccgc ctgttcgccc gaacctgccg ccgaaaaaac tgtatccgcc gcatccgcat
     4981 ctgccgccac actgaccgtg ccgaccgcgc ggggcgatgc cgttgtgccg aagaatcccg
     5041 aacgcgtcgc cgtgtacgac tgggcggcgt tggatacgct gaccgaattg ggcgtgaatg
     5101 tgggcgcaac caccgcgccg gtgcgcgtgg attatttgca gcctgcattt gacaaggcgg
     5161 caacggtggg gacgctgttc gagcccgatt acgaagccct gcaccgctac aatcctcagc
     5221 ttgtcattac cggcgggccg ggcgcggaag catatgaaca gttggcgaaa aacgcgacca
     5281 ccatagatct gacggtggac aacggcaata tccgcaccag cggcgaaaag cagatggaga
     5341 ccttggcgcg gattttcggc aaggaagcgc gcgcggcgga attgaaggcg cagattgacg
     5401 cgctgttcgc ccaaacgcgc gaagccgcca aaggcaaagg acgcgggctg gtgctgtcgg
     5461 ttacgggtaa caaggtgtcc gccttcggca cgcagtcgcg gttggcaagt tggatacacg
     5521 gcgacatcgg cctaccgcct gtagacgaat ctttacgcaa cgaggggcac gggcagcctg
     5581 tttccttcga atacatcaaa gagaaaaacc ccgattggat tttcatcatc gaccgtaccg
     5641 ccgccatcgg gcaggaaggg ccggcggctg tcgaagtatt ggataacgcg ctggtacgcg
     5701 gcacgaacgc ttggaagcgc aagcaaatca tcgtcatgcc tgccgcgaac tacattgtcg
     5761 cgggcggctc gcggcagttg attcaggcgg cggagcagtt gaaggaggcg tttgaaaagg
     5821 cagaacccgt tgcggcgggg aaagagtagg gagtcgtctg aaaacggagt ttccgaagga
     5881 agcggggggt ttctgcgaag ctaaagtgcg gtttcaacga attgaaaagc agcctgtatg
     5941 ttgaaaatac cgctcaagca aacctacggt ttgccgccct ctccctagcc ctctcccaca
     6001 gggagagggg attggggtgc aggctgcctt taaggtttag gcaaattttt aacttcgttg
     6061 aagctgcgat ttcagaagct ccgttttagc ttcgcagaaa ctccgcttcc ttcgaaagct
     6121 ccgttttcag acgacctttt ggagtaccgc aggcacacgc atcgaacggc tgaatcaaag
     6181 ttcagaccga tggcagcccg cacccgagtt tatgcggcaa acagcgaggc tacggcaacc
     6241 cgtcccctct ccctgtggga gagggttagg gagagggcag taagccgtag gcttacatca
     6301 aagtcgataa cgctttcaca aagcctgtgt gcactgaaaa ctgaaaggtc gtctgaaaac
     6361 ggagctttcg aaggaagcag agtttctgcg aagctaaaac cgaagctgca aaaaatcgaa
     6421 aagcagcctg cacgttgaaa atgccgccca agcaaaccta cggtttgccg ccctctccct
     6481 agccctctcc cacagggaga ggggattggg gtgcaggcta cctttaaggt ttaggcaaat
     6541 ttttaacttc gttgaagctg cgatttcaga agctccgttt tcagacgacc ttttggaaca
     6601 ccacaggcac acgcatcgaa cggctgaatc aaagattcag accgatggca gtccgcaccc
     6661 gagtttatgc ggcaaacagc gaggctacgg caacccgtcc cctctccctg tgggagaggg
     6721 ttagggagag ggcggtaagc cgcaggctta catcaaagcc gataacgctt ccgttacaac
     6781 tccgcccact gaaagcagcc tgcaacgaag ccaaaacgac aaaccgcatc gtaaaccacc
     6841 caacccatag gagaacccca tgcaaaacga aaccatcaac ccgaaacagc accttgccgc
     6901 catcaaagaa tactggcagc ccgaaatcat caaccgccac gggttccaat tccgcttggt
     6961 caaacttttg ggcgattacg gctggcatac gcacggatac agcgacaaag tgctgtttgc
     7021 cgtggagggc gacatggcgg tggacttcgc cgacggcggc agcatgacga tacgcgaggg
     7081 cgagatggcg gtcgtgccga agtcggtgtc gcaccgcccg cgttcggaaa acggctgctc
     7141 ggtggtgctg attgagttgt ccgacccgtc cgaggccgtc tgaaaacgaa gtttccgaag
     7201 gaagctgagt ttctgcgaag ctaaaagcag cctgcacctt caatcaatat gccgaaaata
     7261 caaccccacc gcacaccaac acacaaagga aatcccatga cacgcttcaa atattccctg
     7321 ctgtttgccg ccctgttgcc cgtgtacgcg caggccgatg tttctgtttc agacgacccc
     7381 aaaccgcagg aaagcactga attgccgacc atcaccgtta ccgccgacca caccgcgagt
     7441 tccaacgacg gctacactgt ttccggcacg cacaccccgc tcgggctgcc catgaccctg
     7501 cgcgaaatcc cgcagagcgt cagcgtcatc acatcgcaac aaatgcgcga ccaaaacatc
     7561 aaaacgctcg accgcgccct gttgcaggcg accggcacca gccgccagat ttacggctcc
     7621 gaccgcgcgg gctacaacta cctgttcgcg cgcggcagcc gcatcgccaa ctaccaaatc
     7681 aacggcatcc ccgttgccga cgcgctggcc gatacgggca atgccaacac cgccgcctat
     7741 gagcgcgtag aagtcgtgcg cggcgtggcg gggctgctgg acggcacggg cgagccttcc
     7801 gccaccgtca atctggtgcg caaacgcccg acccgcaagc cattgtttga agtccgcgcc
     7861 gaagcgggca accgcaaaca tttcgggctg ggcgcggacg tatcgggcag cctgaacacc
     7921 gaaggcacgc tgcgcggccg cctggtttcc accttcggac gcggcgactc gtggcggcag
     7981 cgcgaacgta gccgcgatgc cgaactctac ggcattttgg aatacgacat cgcaccgcaa
     8041 acccgcgtcc acgcaggcat ggactaccag caggcgaaag aaaccgccga cgcgccgctc
     8101 agctacgccg tgtacgacag ccaaggttat gccaccgcct tcggcccgaa agacaacccc
     8161 gccacaaatt gggcgaacag ccgccaccgt gcgctcaacc tgttcgccgg catcgaacac
     8221 cgcttcaacc aagactggaa actcaaagcc gaatacgact acacccgcag ccgcttccgc
     8281 cagccctacg gcgtagcagg cgtgctttcc atcgaccaca acaccgccgc caccgacctg
     8341 attcccggtt attggcacgc cgacccgcgc acccacagcg ccagcgtgtc attgatcggc
     8401 aaataccgcc tgttcggccg cgaacacgat ttaatcgcgg gtatcaacgg ttacaaatac
     8461 gccagcaaca aatacggcga acgcagcatc atccccaacg ccattcccaa cgcctacgaa
     8521 ttttcccgca cgggtgccta cccgcagcct gcatcgtttg cccaaaccat cccgcaatac
     8581 ggcaccaggc ggcaaatcgg cggctatctc gccacccgtt tccgcgccgc cgacaacctt
     8641 tcgctgatac tcggcggcag atacagccgt taccgcaccg gcagctacga cagccgcaca
     8701 caaggcatga cctatgtgtc cgccaaccgt ttcaccccct acacaggcat cgtgttcgac
     8761 ctgaccggca acctgtctct ttacggctcg tacagcagcc tgttcgtccc gcaatcgcaa
     8821 aaagacgaac acggcagcta cctgaaaccc gtaaccggca acaatctgga agccggcatc
     8881 aaaggcgaat ggcttgcagg ccgtctgaac gcatccgccg ccgtgtaccg cgcccgtaaa
     8941 aacaacctcg ccaccgcagc aggacgcgac ccgagcggca acacctacta ccgcgccgcc
     9001 aaccaagcca aaacccacgg ctgggaaatc gaagtcggcg gccgcatcac gcccgaatgg
     9061 cagatacagg caggttacag ccaaagcaaa acccgcgacc aagacggcag ccgcctgaac
     9121 cccgacagcg tacccgaacg cagcttcaaa ctcttcactg cctaccactt tgcccccgaa
     9181 gcccccagcg gctggaccat cggcgcaggc gtgcgctggc agagcgaaac ccacaccgac
     9241 cctgccacgc tccgcatccc caaccccgcc gccaaagccc gcgccgccga caacagccgc
     9301 caaaaagcct acgccgtcgc cgacatcatg gcgcgttacc gcttcaatcc gcgcgccgaa
     9361 ctgtcgctga acgtggacaa tctgttcaac aaacactacc gcacccagcc cgaccgccac
     9421 agctacggcg cactgcggac agtgaacgcg gcgtttacct atcggtttaa at
//
LOCUS       DAXISH010000068         9378 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.068, whole genome shotgun sequence.
ACCESSION   DAXISH010000068 DAXISH010000000
VERSION     DAXISH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9378
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.068"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            456..899
                     /locus_tag="ACFOV4_001786"
                     /pseudo
     CDS             456..899
                     /locus_tag="ACFOV4_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005694496.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
     gene            complement(1107..2492)
                     /gene="pntB"
                     /locus_tag="ACFOV4_001787"
     CDS             complement(1107..2492)
                     /gene="pntB"
                     /locus_tag="ACFOV4_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008750 - proton-translocating NAD(P)+
                     transhydrogenase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HFC7619742.1"
                     /translation="MSSGLVTAAYIVAAILFIFSLAGLSKQETAKQGCYSGIAGMAVA
                     LFVTVFSDNTHGLGWIIIAMLIGAAIGIYKAKKVEMTEMPELIALLHSFVGLAAVLVG
                     FNSYIEPGNVSHDMHTIHLVEVYLGIFIGAVTFTGSLVAFGKLNGKISSSPLQLPAKH
                     KLNALALAVSFVLLLVFVGINGSGFILLIMTLIALAFGWHLVASIGGADMPVVVSMLN
                     SYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFVSVIAGGFGSDSG
                     TLSSGSQEIGEYREVKAADIAEMLKGANNVIITPGYGMAVAQAQYPVAEITELLRKNG
                     TEVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFPETDVVLVIGANDTVN
                     PAAQTDPNSPIAGMPVLEVWKAKEVVVFKRSMNTGYAGVQNPLFFNENSVMCFGDAKK
                     TVDDILSELKK"
     gene            complement(2558..2941)
                     /locus_tag="ACFOV4_001788"
     CDS             complement(2558..2941)
                     /locus_tag="ACFOV4_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HFC7619743.1"
                     /translation="MTFAYWCILIACLLPLFCAAYAKKAGGFRFKDNHNPRDFLARTQ
                     GTAARAHAAQQNGFEAFAPFAAAVLTAHATGNAGQATVNTLAGLFILFRLAFIWCYIA
                     DKAALRSLMWAGGFACTVGLFVAAA"
     gene            complement(2945..4486)
                     /locus_tag="ACFOV4_001789"
     CDS             complement(2945..4486)
                     /locus_tag="ACFOV4_001789"
                     /EC_number="7.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HFC7619744.1"
                     /translation="MKIGIPRESLSGETRVACTPATVALLGKLGFETVVESGAGLAAS
                     LDDAAYQTAGATVADKAAVWVCPLIYKVNAPSEQELPLLNEGQTIVSFLWPRQNEALV
                     EALRAKKVNALAMDMVPRISRAQALDALSSMANISGYRAVIEAANAFGRFFTGQITAA
                     GKVPPAQVLVIGAGVAGLAAIGTANSLGAVVRAFDTRLEVAEQIESMGGKFLKLDFPQ
                     ESGGSGDGYAKVMSDEFIAAEMKLFAEQAKDVDIIITTAAIPGKPAPKLITKEMVESM
                     KSGSVIVDLAAATGGNCELTRPGELSVTGNGVKIIGYTDMANRLAGQSSQLYATNLVN
                     LTKLLSPNKDGEITLDFEDVIIRNMTVTRDGEITFPPPPIQVSAQPQQTPSEKAAPAA
                     KPEPKPVPLWKKLAPAVIAAVLVLWVGAVAPAAFLNHFIVFVLACVIGYYVVWNVSHS
                     LHTPLMSVTNAISGIIVVGALLQISQGNGFVTLLAFIAILIASINIFGGFFVTRRMLN
                     MFRKG"
     gene            4776..5609
                     /gene="serB"
                     /locus_tag="ACFOV4_001790"
     CDS             4776..5609
                     /gene="serB"
                     /locus_tag="ACFOV4_001790"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036424 - L-phosphoserine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
                     /protein_id="HFC7619745.1"
                     /translation="MPHALVLQFPSAETLPSDFPSRLPEPDYADEKRMRFIVEEGFSL
                     SEKDAALLGSRQIDHAVLSDMDFGELGLIVSDMDSTLITIECVDEIAAGVGLKDKVAE
                     ITERSMRGELDFEQSLRSRVALLAGLDEQILADVYENVLKLSPSAEFLLDECKRHNVK
                     FLLVSGGFTFFTERLQQRLGFEYQHANILEIENGRLTGRLKGRIIDAQAKADLLREYR
                     SRLGLQPHQVLAMGDGANDIPMLKEAGVGVAYRAKPKAQAAADACINFGGLERVRGLF
                     G"
     gene            5673..6896
                     /locus_tag="ACFOV4_001791"
     CDS             5673..6896
                     /locus_tag="ACFOV4_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFC7619746.1"
                     /translation="MGRRKLWFALAAAGVIGGLVGIVLTELMHFIQHTAYGYGADGVY
                     TSFREGVAQASGMRRVAVLTLCGAVAGSGWWLLKRFGKPQIEIKAALKQPLQGLPFLT
                     TVFHVLLQIITVGLGSPLGREVAPREMTAAFAFAGGKRLGLDEGEMRLLIACASGAGL
                     AAVYNVPLASTLFILEAMLGVWTQQAVAAALLTSVIATAVARIGLGDVQQYHPANLAV
                     NTSLLWFSAVIGPILGATAVFFQRTAQKFPFIKRDNIKIIPLAVCMFALIGVIAVWFP
                     EILGNGKAGNQLTFGGLTGWQHSLELTAVKWLVVLMALAAGAYGGLITPSMMLGSTIS
                     FAAAAAWNSVFPEMPSGSAAVVGAAVFLGVSLKMPLTAIVFVLELTYAPLSLLLPLCI
                     GMAGALGTSGKMGFK"
     gene            7057..8637
                     /gene="purH"
                     /locus_tag="ACFOV4_001792"
     CDS             7057..8637
                     /gene="purH"
                     /locus_tag="ACFOV4_001792"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFC7619747.1"
                     /translation="MSVIKRALISLSDKAGAVEFAQTLTKLGVEILSTGGTAKLLADA
                     GVPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLGEHVAKMEEHGIGNIDLVCV
                     NLYPFAATIAKPNCTLEDAIENIDIGGPTMVRSAAKNWKHVAIVTDTADFPAIAAELE
                     ANNGALSDKTRFNLSRKAFSHTAQYDGMISNYLTSLSDDILSGTPEIGEFPSQFNQSW
                     IKVQDMRYGENPHQRAAFYRDIDPAAGSLSAYKQLQGKELSYNNIADADAAWEAVKSF
                     DAPACVIVKHANPCGVAVAADTLTAYKLAYVTDTTSAFGGIIAFNREVDGETVKQITD
                     NQFMEVLMAPKFTAEALEIAAAKKNVRVLEVPLEAGANRFELKRVGGGLLVQTPDICR
                     ISRADLKVVSKRQPTEQEWNDLLFVWNVAKYVKSNAIVFGKGGQTYGIGAGQMSRVDS
                     TRITARKAQDANFDLNGACAASDAFFPFRDGVDVIAEQGIKAIIHPAGSMRDQEVFDA
                     ADEHGIAMVVTGIRHFRH"
     gene            9250..>9378
                     /locus_tag="ACFOV4_001793"
     CDS             9250..>9378
                     /locus_tag="ACFOV4_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFC7619748.1"
                     /translation="MLIHYIDIAKRNFVIAVSSLSKTKTETNNPKGIAHTIEYLKKH"
BASE COUNT         2139 a         2515 c         2623 g         2101 t
ORIGIN      
        1 ggtccggatg cctgattatc gggtatccgg ggaggattaa ggggatattt gggtagaatt
       61 aggaggtgtt atggagcgaa aacagccgaa aacctgtgtt tgggtttcgg ctgtcgggag
      121 ggaaaggaat tttgcaaagg tctcttttcg tcattcccgc cacttttcgt cattcccgcg
      181 aaagcgggaa tctagaatct cggactttca gataatcttt gaatattgct gttgttctaa
      241 ggtctagatt cccgcctgcg cgggaatgac gaatccatcc gtacggaaac ctgcaccacg
      301 tcattcccac gaacctacat tccgtcattc ccacgaaagt gggaatccag gacgaaaaat
      361 ctccagaaac cgttttaccc gataagtttc cgcaccgaca ggtctggatt cccgcctgcg
      421 cgggaatgac gatgcaggta tttctgacaa ttcccggcta tgatgttgag gcagaaatcg
      481 aaaaattcgt ttggatggat gctgtgattt ggcagatgcc gggctggtgg atgcacgagc
      541 cttggacagt gaaaaaatac atagacggag tattaaccgc tggacacggc aaactctacc
      601 aaagcgacgg cagacacagc gtcaatccga ctgagggcta cggcacaggc ggcttgttgc
      661 aaggcaaaaa acatatgctt tcactgactt ggaatgcgcc gattgaggcg tttacccgcg
      721 aaggcgattt ctttgagggc aaaggcgttg atgttttgta tatgcacttc cacaaagcca
      781 acgagttttt gggtatgacc cgcctgccga cattcttatg taacgatgtg gttaaaaatc
      841 cgcaagtgga aaaatacttg gcagattatc aggcacactt ggaaaaagtg ttcggctaat
      901 taaaaatcca tcttcaacac ggagatggat tttgtttgtt tcgttgattt tgtgtcagtt
      961 tcagatgtag gtgcttattc ggacgggccg tctgaaaatg tttgccccaa tgcaaaaaaa
     1021 tcactgcaaa ccttcataaa cggggtttgc agtgattttt tcaaatcaaa cagattgaaa
     1081 acctgcgccg aattgttcag acggcattat tttttcagtt cggacagaat gtcatctacg
     1141 gttttcttcg catctccgaa acacatcacg ctgttttcgt tgaagaacag tgggttttgt
     1201 acacctgcgt agccggtatt catcgagcgt ttgaagacga cgacttcttt tgccttccac
     1261 acttccaaca cgggcatacc cgcaatcggg ctgttcgggt cggtttgggc ggcggggttg
     1321 acggtgtcgt tcgcaccgat gaccaagacc acatcggttt cggggaagtc gtcgttgatt
     1381 tcgtccattt ccaaaacgat gtcgtagggg actttggctt cggcgagcag tacgttcata
     1441 tgaccgggca ggcggccggc gacggggtgg atgccgaagc gtacttcggt gccgttttta
     1501 cgtaaaagct cggtgatttc ggcaacgggg tattgcgctt gtgcgactgc cataccgtag
     1561 cccggggtaa tgatgacatt gtttgcgcct ttcagcattt cggcaatatc ggcagctttg
     1621 acttctcggt attcccctat ctcttggctg ccggaagata atgtgccgct gtcgctgccg
     1681 aaaccgccgg caattaccga gacaaacgag cggttcatgg ctttgcacat aatgtaggac
     1741 agaatcgcgc cgcttgagcc gaccagcgcg ccggtaacga tgagcaggtc gttggagagc
     1801 atgaagcctg ccgctgcggc cgcccagccg gagtaggagt tgagcatgga cacgaccacg
     1861 ggcatatctg cgccgccgat ggaggcaacc aagtgccagc cgaatgcgag ggcaatcagg
     1921 gtcataatca gcaggatgaa gccgctaccg ttaatgccga cgaatacgag cagcaacaca
     1981 aacgatacgg cgagcgccag tgcgttgagc ttgtgtttgg cgggcagttg cagcgggctg
     2041 ctgctgattt tgccgttgag tttgccgaat gcgaccagcg agccggtaaa ggttaccgcg
     2101 ccgatgaaaa tgcccaaata gacttcgacc agatggatgg tgtgcatatc gtgcgaaacg
     2161 ttgcccggct cgatatagct gttgaagccg accaaaaccg ccgctaggcc gacgaagctg
     2221 tgcagcaggg caatcagttc gggcatttcg gtcatttcca cctttttggc tttgtagatg
     2281 ccgattgccg cgccgatgag catggcgatg atgatccagc ccagtccgtg ggtattgtcg
     2341 gaaaaaacag ttacaaaaag ggcgaccgcc ataccggcga taccggaata gcagccctgt
     2401 ttggcggttt cctgtttgga cagccccgcc agtgagaaga tgaataaaat tgcggcaacg
     2461 atatacgccg ctgttacgag tcctgaagac atggaaattc tccgattttc gatgatttgt
     2521 ttttaatgcc gtctgaactg ttcagacggc atctgtttca agcagccgcg acaaacagcc
     2581 cgacggtgca ggcaaatccg cccgcccaca tcagcgagcg caatgctgct ttgtctgcga
     2641 tgtagcacca gataaaggcg aggcggaaca ggatgaacag gccggcaagc gtgttgacgg
     2701 ttgcttgtcc ggcattgccg gttgcgtgtg ccgtcaaaac ggcggcggca aacggtgcaa
     2761 aggcttcaaa accgttttgc tgcgcggcgt gggcacgggc ggctgtgcct tgcgtgcgcg
     2821 ccagaaaatc gcgcggattg tggttgtctt taaaccggaa tccgcccgct tttttggcat
     2881 atgccgcaca aaaaagcggc aataagcagg caatcaggat gcaccaatag gcaaaagtca
     2941 tgctttatcc tttcctaaac atattcaaca tgcggcgcgt tacgaagaag ccgccgaaga
     3001 tattgatgct ggcaatcagg atggcgatga aggcaagcag ggtaacgaaa ccgttgcctt
     3061 ggctgatttg cagcagcgcg ccgacgacga tgatgccgga gatggcgttg gttaccgaca
     3121 tcagcggtgt gtgcagcgag tggctgacgt tccaaacgac atagtagccg atgacgcagg
     3181 cgaggacgaa gacgataaag tggttcagga atgctgcggg tgcgaccgcg ccgacccaca
     3241 gtaccaacac ggcggcgatg acggcgggcg cgagtttttt ccacagggga acgggtttcg
     3301 gttcgggctt ggcggcaggc gcggcttttt cagacggcgt ttgctgcggt tgggcggaaa
     3361 cttgaatcgg cggaggcggg aaggtgattt cgccgtcgcg ggtaacggtc atgttgcgga
     3421 taatcacgtc ttcaaaatcc agcgtgattt cgccgtcttt gttcgggctt aacaacttgg
     3481 tcaggttgac caggttggtg gcgtaaagct gggaagactg tccggcaagg cggtttgcca
     3541 tgtcggtgta gccgatgatt ttcacgccgt tgccggttac ggacaattcg cccggtcggg
     3601 tgagttcgca gttgccgccc gtcgccgccg ccaaatcgac gatgacggag ccggatttca
     3661 tgctttccac catttctttg gtaatcagct tgggcgcggg tttgcccgga atggcggcgg
     3721 tggtgatgat gatgtccacg tctttcgcct gctcggcaaa gagcttcatc tcggcggcga
     3781 taaattcgtc gctcatcact ttggcatagc cgtcgccgct gccgcccgat tcttgcggga
     3841 agtcgagttt caaaaacttg ccgcccatcg attcgatttg ttccgccact tccaagcggg
     3901 tatcgaacgc gcgcaccact gcgccgagcg agtttgccgt accgatcgcc gccaaacctg
     3961 ccacacctgc gccaatcacc aaaacctgcg cgggcggcac tttgccggcg gcggtaattt
     4021 gaccggtgaa gaaacggccg aaggcgttgg cggcttcaat tacggcgcgg tagccgctga
     4081 tgtttgccat cgaagacaaa gcgtccaaag cctgcgcgcg cgaaatgcgg ggcaccatat
     4141 ccatcgccag cgcgttcact ttcttggcgc gcaaggcttc gaccaaagcc tcgttttggc
     4201 gcggccacag gaagctgacg atggtttgac cttcgttcaa aagcggcagt tcctgttcgg
     4261 acggcgcgtt gaccttataa atcaaagggc agacccaaac cgccgctttg tcggcaacgg
     4321 ttgcgcctgc tgtttggtaa gcggcatcgt ccaaacttgc cgccaaacct gcaccgcttt
     4381 cgacaacggt ttcaaagccc agtttgccca gcagggcgac ggtggcgggc gtgcaggcga
     4441 cgcgggtttc gccggataat gactcgcgtg ggataccgat tttcatctct gaatcctttt
     4501 tcgggtagtt tatatgtatc gtgggttaaa tttaaatcgg ggcagggcgg agcaacgccg
     4561 taccggttta aaaccgattc acttcaaatg ttaatatatt ttagataatc cccttataac
     4621 gaattttcat caggctggca atagttgcgg cattttcccg tgttgtccga cacatactgc
     4681 cgtttgcgtt tgaagtcatt ttccgattgc agtcccgccc gccgtaacat tctttgccgt
     4741 ttcactatat aatccgcatt ttttgagccg ccgttatgcc gcacgccctc gtcctccaat
     4801 ttccctccgc cgaaaccctg ccttccgact tcccctcacg cctgcccgaa cctgattatg
     4861 ctgatgaaaa gcgtatgcgt tttatcgttg aagaagggtt ttctttaagc gaaaaagacg
     4921 cggcgttact tggcagccgt caaatcgacc acgccgtgtt gtcggatatg gattttggcg
     4981 aactcggttt gattgtcagc gatatggatt cgacgctgat taccatcgaa tgcgtcgatg
     5041 aaattgcggc aggcgtgggt ttaaaagaca aagtagcgga aattaccgag cgttcgatgc
     5101 gcggcgaact cgatttcgaa cagtctttac gcagccgcgt cgcgctgttg gcgggattgg
     5161 acgaacagat tttggcggac gtttatgaaa acgttttgaa gctctcgccc agtgcggaat
     5221 ttttgttgga cgaatgcaaa aggcacaatg tgaaattcct gctggtgtcc ggcgggttca
     5281 cgttttttac cgaacgtctg caacaacgcc tcggcttcga ataccaacac gccaatattt
     5341 tggaaattga aaacggcagg ctgaccggac gtttgaaagg cagaattatc gacgcgcagg
     5401 caaaggcgga tttattgcgc gaataccgca gccgcctcgg attgcagccg catcaggtgt
     5461 tggcgatggg cgacggtgcg aacgatattc cgatgctcaa agaagcgggc gtgggcgtgg
     5521 cttaccgtgc caaaccgaaa gcgcaggcag ccgccgatgc ctgtatcaac ttcggcggtt
     5581 tggagcgtgt acgcggcctg ttcggatagg cggataggaa acggatgccg tctgaaaggt
     5641 tttcagacgg catttgaacg gcaggaacga cagtgggacg cagaaaactt tggtttgccc
     5701 tggcagcagc gggcgttatc ggcggtttgg tcggcattgt gctgacggaa ctgatgcact
     5761 tcatacagca tacggcatac ggttatggcg cggacggcgt gtacacttcg ttccgcgaag
     5821 gcgtggcaca ggcttccggt atgcggcgcg ttgccgtgct gacgctgtgc ggcgcggtcg
     5881 caggcagcgg ctggtggttg ctgaaacgtt tcggcaagcc gcaaatcgaa atcaaagccg
     5941 ccttgaaaca gccgttgcag gggctgccgt ttctgacgac ggttttccat gttctgctgc
     6001 aaatcataac ggtcggactc ggttcgccgc tcggacgcga agtcgccccg cgcgaaatga
     6061 ccgccgcgtt tgcttttgcc ggcggcaaac gcttgggttt ggatgaaggc gaaatgcggc
     6121 tactgattgc ttgcgcttcg ggtgcgggtt tggcggccgt gtataacgtg ccgctcgcct
     6181 cgacgctgtt tatcctcgaa gcgatgttgg gcgtgtggac gcagcaagcc gtcgccgccg
     6241 cattgctgac ttccgtcatc gccaccgccg tcgcgcgcat cggcttaggc gacgtgcagc
     6301 aatatcatcc cgccaacctt gccgtaaaca cttcattact ttggttttcc gccgtcatcg
     6361 gcccgatact gggcgcaacc gccgtctttt tccagcgcac cgcccaaaaa ttccccttca
     6421 tcaagcgcga caacatcaaa atcattccct tggcagtctg catgtttgcg ctcatcggcg
     6481 tgattgccgt ttggtttccc gaaattttgg gcaacggcaa agcaggcaac caactgacct
     6541 ttggcggttt gaccggttgg caacacagcc ttgagctgac cgccgtcaaa tggctggttg
     6601 tcttgatggc gttggcggca ggcgcatacg gcggactgat tacgccgtct atgatgctcg
     6661 gcagcaccat ttcttttgca gccgccgccg cgtggaacag cgttttcccc gaaatgccgt
     6721 ctggaagcgc ggcagtcgtc ggagcggcgg tgtttctcgg cgtatcgctc aaaatgccgc
     6781 tgaccgccat tgtgttcgta ttggaactga cctacgcgcc gctgtccctg ctgctgcctt
     6841 tgtgcatcgg catggcgggg gcattgggaa catcgggaaa aatgggcttc aaataaatgc
     6901 cgacaaatgc cgtctgaaag gttttcagac ggcatttctt tgtaaattgt cagcaatatc
     6961 tgcaaaaacc tactgccaaa aaactagaaa tagcggataa taccgccccg aaaaagttcc
     7021 cctttcccca tccaactgtc agaaaaggaa gccccaatgt ccgtcatcaa acgcgccctg
     7081 atcagcctgt ccgacaaggc aggcgcggtc gaatttgccc aaaccctgac caagctcggt
     7141 gtcgaaatcc tctccaccgg cggcacggcg aaactgcttg ccgatgcggg cgttcccgtg
     7201 attgaagtcg ccgactatac cggcttcccc gaaatgctcg acggccgcgt gaaaacgctg
     7261 catccgaaaa tccacggcgg tattttgggt cggcgcgatt tgggcgaaca cgtcgccaag
     7321 atggaagaac acggcatcgg caatatcgac cttgtgtgcg tcaaccttta tcccttcgcc
     7381 gccaccatcg ccaaaccaaa ctgcacactg gaagacgcga ttgaaaacat cgacatcggc
     7441 ggcccgacca tggtgcgttc tgccgcaaaa aactggaaac acgtcgccat cgttaccgac
     7501 accgccgact tccccgccat cgccgccgaa ctcgaagcca acaacggcgc gttgagcgac
     7561 aaaacccgct tcaacctgtc gcgcaaagcg ttcagccaca ccgcccaata cgacggcatg
     7621 atttccaact acctgacctc gctttcagac gacatcttga gcggcacgcc cgaaatcggt
     7681 gaattcccga gccagttcaa ccaaagctgg attaaagtgc aagacatgcg ctacggcgaa
     7741 aacccgcatc agcgcgccgc gttctaccgc gatattgacc ccgccgcagg cagcctttcc
     7801 gcctacaaac aactgcaagg caaagaattg tcttacaaca acatcgccga tgccgatgcc
     7861 gcatgggaag ccgtcaaatc ctttgacgcg ccagcctgcg tgatcgtcaa acacgccaat
     7921 ccgtgcggcg tcgccgttgc agccgataca ttgaccgcct acaaactcgc ctacgtcacc
     7981 gacaccacca gcgcgttcgg cggcatcatc gccttcaacc gcgaagtgga cggcgaaacc
     8041 gtcaaacaga ttaccgacaa ccagtttatg gaagtcttga tggcgccgaa gtttaccgcc
     8101 gaagccctcg aaatcgccgc cgccaagaaa aacgtgcgcg tattggaagt gccgcttgag
     8161 gcaggcgcaa accgcttcga actcaaacgc gtcggcggcg gactgttggt acaaacgccc
     8221 gacatctgcc gcatcagccg cgccgatttg aaagtcgtct ccaaacgcca accgaccgag
     8281 caggaatgga acgatttgct gttcgtctgg aacgtcgcaa aatacgtcaa atccaacgcc
     8341 atcgtgttcg gcaaaggcgg acaaacctac ggcatcggtg caggccaaat gagccgcgtg
     8401 gacagcaccc gcatcaccgc ccgcaaagcg caggacgcca atttcgacct caacggcgcg
     8461 tgtgccgcct ccgatgcctt cttccccttc cgcgacggcg tggatgtgat tgccgaacag
     8521 ggcattaaag ccatcatcca tccggcaggt tcgatgcgcg atcaagaagt cttcgacgcg
     8581 gcagacgaac acggcattgc gatggtggta accggcatcc gccacttccg ccattaaggc
     8641 agatgaacaa ggcaatgccg tctgaagggc tttcagacgg cattttgcgc tattttgtga
     8701 aggtagggat gacggttcgg gtattcctga cagggtggat tttcaaggtg ttgtataggg
     8761 tgtaggagga ttcgtaaaag gtgggatgca gggtgtgctt cagcccgctg catcaaaaat
     8821 ttttggagaa ccggcgggag tcggcggttt tggtttcggc ggggacggtg gaaatgggta
     8881 acattgacgg aatcgacgga agcggtgggc tgaagcccac ccttgtatat tggaatcact
     8941 gtatcatagc aacaaaccgc ccggccgcca cccgcgccca cccaaggcac acaaccgttg
     9001 cgtagctcag ggagcggcag ggcaacccat cgacacaacc ggacagttgc cggacaacac
     9061 aaccgaatgc aaggcaggtt tatgatgagt acccaatacc attacgcagg tatagtgaat
     9121 taaatctaaa ccagtacagc gttggttcgc cttagctcaa agagaacgat tctctaaggt
     9181 gctgaagcac caagtgagtc ggttccgtac tatccgtact gtctgcggct cgccgccttg
     9241 tcctgatttt tgttaattca ctatatcgac atcgccaaac gaaacttcgt catcgccgtt
     9301 tcgtctttgt ctaaaaccaa aaccgaaacc aacaacccca aaggtatcgc ccatactatc
     9361 gaatacctta aaaaacac
//
LOCUS       DAXISH010000069         9359 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.069, whole genome shotgun sequence.
ACCESSION   DAXISH010000069 DAXISH010000000
VERSION     DAXISH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9359
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.069"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(263..2953)
                     /gene="glnE"
                     /locus_tag="ACFOV4_001794"
     CDS             complement(263..2953)
                     /gene="glnE"
                     /locus_tag="ACFOV4_001794"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008882 - [glutamate-ammonia-ligase]
                     adenylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HFC7619749.1"
                     /translation="MSDNRLDTARRHSLFLARQLDNGKLKPEIFLPMLDKVLTEADFQ
                     AFADWDKIRAEENEEELARQLRGLRRYVVSQIIVRDINRISDLNEVTRTITLFADFAV
                     NTALDFAYAYYRDMYGTPIGRYTKSPQHLSVVAMGKAGGYELNVSSDIDLIFVYPESG
                     DTDGRRERGNQEFFTKVGQKLIALLNDITADGQVFRVDMRLRPDGDSGALVLSETALE
                     QYLITQGREWERYAWCKGRVVTPYPNGIKSLVRPFVFRKYLDYGAYEAMRKLHRQISS
                     EVSKKGMADNIKLGAGGIREVEFIAQIFQMIRGGQMRALQLKGTQETLKKLAETGIMP
                     SENVETLLAAYRFLRDVEHRLQYWDDRQTQTLPASPEQQQLLAESMGFDSYAAFSDDL
                     NAHRTKVNQLFNEILSEPEEQTLDTSEWQWAWQEKPDEEGRRCRLKAHGFDAETVAAR
                     LDQIRHGHKYRHLSAHAQPRFDAVVPLFVQAAAEQSNPTDTLMRLLDFLENISRRSAY
                     LAFLNEHPQTLAQLAQIMGQSSWVAAYLNKYPILLDELISAQLLDTAFDWQALAAALS
                     DDLKACGGDTEAQMDTLRRFQHTQVFRLAVQDLAGLWTVESLSDQLSALADTILAAAL
                     LCAWADMPKKHRDTPQFAVVGYGKLGGKELGYASDLDLVYLYDDPHPDAGDVYSRLAR
                     RLTNWLSAATGAGSLYETDLRLRPNGDAGFLAHSIAAFEKYQRENAWTWEHQSLTRAR
                     FICGTPEIQTAFDRIRTEMLTAERDQTALAGEIIEMREKMFPTHPPADSNVKYARGGV
                     VDVEFIVQYLILAHARQYPQLLDNYGNIALLNIAADCSLIDKNLAEQSRTAYRFYRRQ
                     QHNTKLRDAAKTEVTGELLAHYGNVRKLWRDVFGEEAATA"
     gene            complement(3151..3486)
                     /locus_tag="ACFOV4_001795"
     CDS             complement(3151..3486)
                     /locus_tag="ACFOV4_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619750.1"
                     /translation="MPSEALSGLQTAFCFPTVYKLSLFLDRNNDLIYLKRLEDMIMGF
                     WNGVAKAAKAVGEGMIEAGNEHKALKMEYAEKSSEELHEIVKSDGFFKNSTREKSAAY
                     AILKERGEV"
     gene            complement(3500..3973)
                     /locus_tag="ACFOV4_001796"
     CDS             complement(3500..3973)
                     /locus_tag="ACFOV4_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2247 family protein"
                     /protein_id="HFC7619751.1"
                     /translation="MNLDLTAQKVRLSWKDILWGYGNKYLGWADVAAYARKMTLSDHD
                     ERVFKLSLINKSNILELKPVLEDLASEMRDYSPKNWLYVLLSDVFHRKEEFEDPLGEV
                     EKIYADFDYPEEIESFVRYMPPKDGYIPSAHTYEENIARLYSHWEHYLNNGGGQG"
     gene            complement(4026..4307)
                     /locus_tag="ACFOV4_001797"
     CDS             complement(4026..4307)
                     /locus_tag="ACFOV4_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619752.1"
                     /translation="MENGQRNNRFPLEKRIFYLEHSGRYLMICALSDYSQNKHTVVMA
                     NFIYPDEKTDWRNLDDLFNELVLEELQASFMDWHPTVEEAISRHLEDFS"
     gene            complement(4394..4717)
                     /locus_tag="ACFOV4_001798"
     CDS             complement(4394..4717)
                     /locus_tag="ACFOV4_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619753.1"
                     /translation="MFKDELNEFIRLISDPESELDEWYLSDFKDEHIWEMQSYEAFSC
                     LREAVPYLFAYPRYGYELLEIISALKETSDTTELFYEPGIVPLLIDLYKEDSYLVNMV
                     KRIFK"
     gene            complement(4856..5035)
                     /locus_tag="ACFOV4_001799"
     CDS             complement(4856..5035)
                     /locus_tag="ACFOV4_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619754.1"
                     /translation="MPSERTFCRSDGIFISFSCLPPFENPLRAALFETKQTPAANRTI
                     LIRSQSKSGGKLLNI"
     gene            complement(5051..6058)
                     /locus_tag="ACFOV4_001800"
     CDS             complement(5051..6058)
                     /locus_tag="ACFOV4_001800"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006222 - UMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HFC7619755.1"
                     /translation="MYPLARRILFALDAEKAHHFTLDALNMVYKLGLIPVTGNRTKPV
                     KLMGLDLPNPVGLAAGLDKNGEYIDALGALGFGFIEIGTVTPNPQPGNPQPRLFRVPE
                     YQGIINRMGFNNHGIDAMIQNIEKSKFSGVLGINIGKNAVTPIENAADDYLICLEKAY
                     AHASYITVNISSPNTKNLRALQGGDELSALLEALKNKQAQLASVHGKYVPLAVKIAPD
                     LDEAQIEDIAHVVKSVEMDGIIATNTTIDKSSLGSHPLAGEQGGLSGLPVHEKSNRVL
                     KLLADHIDGKLPIIGVGGIMEGRDAAEKIRLGATAVQVYSGLIYKGPALVKECLKALA
                     Q"
     gene            6290..6526
                     /gene="acpP"
                     /locus_tag="ACFOV4_001801"
     CDS             6290..6526
                     /gene="acpP"
                     /locus_tag="ACFOV4_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFC7619756.1"
                     /translation="MSNIEQQVKKIVAEQLGVNEADVKNESSFQDDLGADSLDTVELV
                     MALEEAFGCEIPDEDAEKITTVQLAIDYINAHNG"
     gene            6682..7929
                     /gene="fabF"
                     /locus_tag="ACFOV4_001802"
     CDS             6682..7929
                     /gene="fabF"
                     /locus_tag="ACFOV4_001802"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFC7619757.1"
                     /translation="MSQRRVVITGLGQVSPVGNTVAEAWDTLLAGKSGIGAITRFDAS
                     DINSRVAGEVRGFDIGQYISAKEARRMDVFIHYGIAAALQAIADSGLDDVENLDKDRI
                     GVNIGSGIGGLPSIEVTGKAVIEGGARKINPFFIPGSLINLISGHVTILKGYRGPSYG
                     MVSACTTGAHAIGNSARLIKYGDADIMVAGGAEGAISTLGVGGFAAMKALSTRNDDPA
                     TASRPWDKGRDGFVIGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNE
                     EGPALAVTRALKDAGINPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSST
                     KSMTGHLLGAAGGVEAVYSILAIHDGKIPPTINIFEQDVEAGCDLDYCANEARDAEID
                     VAISNSFGFGGTNGTLVFKRFKG"
     gene            complement(8171..9124)
                     /locus_tag="ACFOV4_001803"
     CDS             complement(8171..9124)
                     /locus_tag="ACFOV4_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HFC7619758.1"
                     /translation="MGFLIGLSRNLTRFTALVILLASAVAFIGPASFAWVKGDVQVLV
                     LGIIMLGMGMTLGREDYRILAQRPLDVFIGAAAQYTVMPLLAIGIAKLFDLSPGLTLG
                     LVLVGTCPGGVSSNIMSFLAKGDVAFSVGMTTVSTVLAPAVTPLWMTCLVGQTVDMDG
                     WGMFRFMLLVTLLPVVLGSAANILLHGKHWFENVRAVMPGVAVLAFACIVGGVASVHG
                     HRFAESALVMVLAIAVHNIAGYVSGYYAAALFGMDTAKKRTLAIEVGVQNAGLATGLS
                     AKFFPGNPESAVAAAVACVWHSVSGTVLGNLFALWDKRRDA"
BASE COUNT         2230 a         2586 c         2365 g         2178 t
ORIGIN      
        1 tagaatgcgc tattttaatg gaaacggcgg ggttttaaac ggttcttatt tgtttgtttt
       61 gatttttgct tgggtaaaaa atcccatcat tcccacaaaa acagaagcct gaaatcccgt
      121 cattcccgcg aaagaggaat ccggtttttg ggtttcagcc attcccgata aatcgcttta
      181 gctctgccgc aaccttaaaa cggcacggta cgaaaatacc gtctgaaacc cagattgtca
      241 ggcttcagac ggcatttttt gttcaggcgg ttgccgcttc ttcgccgaac acgtcccgcc
      301 acaatttcct gacattgccg taatgtgcca acagttcgcc ggttacttcg gtttttgccg
      361 cgtcgcgcag tttggtgttg tgctgctgcc ggcggtagaa gcggtaggcg gtgcggcttt
      421 gttcggcgag gtttttgtcg ataaggctgc agtcggcggc gatgtttaag agggcgatgt
      481 tgccgtagtt gtccaagagt tgcggatact ggcgggcatg ggcaagtatc agatattgga
      541 cgataaattc gacatcgacc acgccaccgc gcgcgtattt gacgttgctg tcggcaggcg
      601 gatgggtggg gaacattttt tcgcgcattt cgataatttc gcctgctaag gcggtttggt
      661 cgcgttcggc agtcagcatt tcggtgcgga tgcggtcgaa ggccgtctga atttcgggtg
      721 tgccgcagat gaagcgggcg cgggtgaggg attggtgttc ccacgtccag gcgttttcgc
      781 gctggtattt ttcaaaggcg gcgatgctgt gggcgaggaa accggcgtcg ccattagggc
      841 gcaggcgcag gtcggtttcg tagaggctgc ctgcgccggt ggcggcggaa agccagttgg
      901 tcaggcgacg ggcgaggcgg ctgtacacgt cgcctgcgtc ggggtgggga tcgtcgtaga
      961 gatagacgag gtcgaggtcg gaggcgtagc cgagttcttt gccgccgagt ttgccgtaac
     1021 caacgacggc gaattgcggg gtgtcgcggt gttttttggg catgtccgcc cacgcgcaca
     1081 gcagggcggc ggcgaggatg gtgtcggcga gggcggagag ttggtcggag agggattcta
     1141 ccgtccacag tccggcgagg tcttggacgg cgagacggaa gacttgggtg tgctggaagc
     1201 ggcgcagggt gtccatttgc gcttcagtat cgccgccgca ggctttgagg tcgtctgaaa
     1261 gggcggcggc gagtgcctgc caatcaaacg cggtatccaa aagctgcgcg ctgatgagtt
     1321 cgtccaacaa aatcggatat ttgttcagat acgccgccac ccaagaactt tggcccataa
     1381 tctgcgccag ttgcgccaag gtttgcggat gttcgttgag gaaggcgaga taggcggatc
     1441 ggcggctgat gttttcgaga aaatccaaca gccgcatcaa tgtatcggtc gggttgcttt
     1501 gctctgccgc cgcctgtacg aacagcggca caaccgcatc gaaacgcggc tgggcgtgtg
     1561 cggaaagatg gcggtattta tggccgtggc ggatttggtc gagccttgcg gcgacggttt
     1621 cggcatcgaa cccgtgcgcc ttcagacggc atcgccgccc ttcttcgtcg ggcttttcct
     1681 gccatgccca ttgccattcg ctggtgtcta gggtttgctc ttcgggttcg ctcaaaattt
     1741 cgttgaacaa ctgattgact ttggtgcggt gggcattgag gtcgtctgaa aaagcggcgt
     1801 agctgtcgaa acccatactt tcggcaagca gttgctgctg ttcgggcgaa gccggcaggg
     1861 tttgggtttg ccggtcatcc cagtattgca ggcggtgttc gacatcgcgc aggaatcggt
     1921 aggcggcaag cagggtttcg acgttttcag acggcatgat cccggtttcg gcaagtttct
     1981 tcagcgtttc ctgcgtgcct ttcagttgca gcgcacgcat ttggccgccg cgtatcatct
     2041 ggaaaatctg ggcgataaat tcgacttcgc ggatgccgcc cgcgccgagc ttgatgttgt
     2101 ccgccatgcc ttttttgctg acttcgctgc tgatttggcg gtgcagctta cgcatcgcct
     2161 catacgcgcc gtaatccaga tatttgcgga acacgaaggg gcgcaccagc gatttgattc
     2221 cgttcggata cggcgtaacc acgcggcctt tgcaccacgc gtagcgttcc cattcgcgcc
     2281 cctgcgtaat caggtattgc tccagcgcgg tttcgctcaa caccaacgcg cccgaatcac
     2341 cgtccggccg cagccgcata tcgacgcgga acacctgccc gtcggcggtg atgtcgttca
     2401 acagcgcaat cagtttctgc ccgactttgg tgaaaaactc ctgattgccg cgttcgcgcc
     2461 tgccgtcggt gtcgcccgat tcgggataga cgaaaatcaa atcgatgtcg gaagacacgt
     2521 tcaactcata gccgcccgcc ttgcccatcg ccaccacgct caaatgctgc ggcgatttgg
     2581 tataacgccc gatcggcgtg ccgtacatgt cccgataata ggcgtaggca aaatccagcg
     2641 cggtattgac ggcaaaatcg gcaaacagcg taatcgtgcg ggttacttcg ttcaaatcgc
     2701 tgatgcggtt tatatcgcgc acgataatct gcgacaccac ataacggcgc aacccgcgca
     2761 actgccgcgc caattcttcc tcgttttctt ccgcacggat tttgtcccag tcggcaaagg
     2821 cttggaaatc cgcttcggtc aaaaccttgt ccagcatagg caggaaaatt tcgggcttga
     2881 gtttgccgtt gtcgagctgg cgggcgagga agagggaatg gcggcgggcg gtgtcgaggc
     2941 ggttgtcgga catttcggat tccgtttgaa aaaatggcag gaagatgatg gcggattcac
     3001 ttcaaatcag gacagggcga ggggatgccg taccggttta aagtcaagcc actatatcat
     3061 agcaaccttc gatgccgtct gaaaccttgc cccgacatcc agacggatgc ctgccgataa
     3121 aaaacagcgg caaatgccgc cgtttcctgt tcacacctcg ccacgctctt ttaaaatagc
     3181 ataagccgca cttttctccc gtgtggaatt tttaaaaaaa ccatcactct tgacgatttc
     3241 atgcagctcc tcacttgatt tctccgcata ttccattttc aacgccttat gctcattgcc
     3301 ggcttcaatc attccctctc ccactgcttt tgctgctttt gccacaccat tccaaaaacc
     3361 cataatcatg tcctccaatc gtttcaaata aataaggtcg ttgtttctgt caagaaacaa
     3421 cgacagttta taaactgtcg gaaaacaaaa tgccgtctga aggccggata atgcttcaga
     3481 cggcatcgga ttgccggttt taaccctgcc ctccgccgtt gttcaaatag tgttcccagt
     3541 gagaatataa ccgggcaata ttttcttcat aggtgtgggc agaaggaata taaccgtctt
     3601 tgggcggcat atacctgaca aatgattcta tttcttccgg ataatcaaaa tctgcataaa
     3661 ttttttcaac ttcccccaaa ggatcctcaa attcttcttt tctatggaat acatcgctta
     3721 agaggacgta cagccaattt ttaggggaat aatccctcat ttccgaagcc aaatcttcca
     3781 gaacaggctt taattcaaga atattggatt tgttgattaa agatagtttg aacacacgtt
     3841 catcatgatc tgaaagcgtc atttttcggg cataagctgc cacatcagcc caacccaagt
     3901 atttattccc atacccccac agaatatcct tccaagaaag acggactttt tgcgcggtta
     3961 aatcaaggtt cattttttac tccgattgcc tgccccgtca ttccgcccct tccgattgac
     4021 gcctgttacg aaaagtcttc caaatgacgg ctgattgcct cttcaacagt cggatgccaa
     4081 tccataaatg aagcctgcaa ttcctctaaa accaactcat tgaataaatc atccaaattc
     4141 cgccaatccg ttttttcatc cggatagatg aaatttgcca taacgacagt atgtttgttt
     4201 tgggaataat ccgataaggc gcaaatcatc agataccgcc ccgaatgctc cagataaaaa
     4261 attcgttttt ccaaaggaaa ccggttattc cgttgcccgt tttccatttt tcatcctttt
     4321 taacgtatcg gcttccgcgt ccttcaaatt gagttacctg ccttccgcca agcaaacgcc
     4381 cgcgcccctt tcatcatttg aatatccgtt tgaccatatt taccagataa ctatcttctt
     4441 tatataaatc aatcagcaaa ggcacgatac ccggctcata aaataattct gtcgtatcag
     4501 atgtttcttt taacgcggaa attatctcca acagttcata cccgtatcgg ggataagcaa
     4561 acaaataggg gactgcttcc cgcaaacatg aaaatgcttc gtaactttgc atttcccata
     4621 tatgttcatc tttaaaatca ctcaaatacc attcatccaa ttcactttcc ggatcggata
     4681 tcaatcggat aaattcattt agttcgtcct taaacatatc aaatccttaa atataaaatc
     4741 ttttgattat ccgccgtatc cttattttcc acatcatgaa tttcaacgcc gttcatattt
     4801 tgcgttttct caaaccgtcc accacggcat aaaattattt tttcatatca attatttata
     4861 tgtttaacaa cttaccgccg gacttgcttt ggctgcgtat caagattgtc cggttcgcgg
     4921 cgggcgtttg ctttgtttca aacagggcgg cgcgtaaggg attttcaaag ggcggcaggc
     4981 aggaaaagga aataaaaatg ccgtctgaac ggcaaaacgt gcgttcagac ggcattttgt
     5041 gcgggacgcg tcattgcgcc aaagccttca aacattcttt gaccaatgcc ggacctttgt
     5101 atatcaatcc gctgtacacc tggacggcag ttgcgcccaa gcggattttc tctgccgcgt
     5161 ccctgccttc cataatgccg cctacgccga taatcggcag cttgccgtcg atgtggtctg
     5221 ccaacagctt caacacccga ttactttttt catgaacggg cagcccgctc aaaccgccct
     5281 gctcgcctgc gagcggatgg ctgccgagac ttgatttgtc gatggtggta ttggtagcga
     5341 tgatgccgtc catttcgacg gatttgacaa cgtgggcgat gtcttcgatt tgtgcttcat
     5401 ccaaatcggg ggcgattttg acggcgagcg ggacgtattt cccgtgtaca gaggcaagct
     5461 gtgcctgttt gtttttcaaa gcctcaagca atgcgctcaa ctcgtcgcca ccttgcagcg
     5521 cgcggaggtt tttagtgttg ggcgaggaaa tattgacggt aatgtaactt gcgtgtgcgt
     5581 aggctttttc gaggcagatt aaataatcat cggcagcgtt ttcaatcggt gttacagcgt
     5641 ttttgccgat gttgatgccc aatacgccgc tgaatttact tttttcgatg ttttgaatca
     5701 tggcatcgat gccgtggttg ttgaagccca tgcgattgat gatgccttga tattcgggaa
     5761 cgcggaagag gcgcggctgc gggttgccgg gctgcgggtt gggcgttacc gtgccgattt
     5821 cgatgaaacc gaagccgagc gcgcccaatg cgtctatata ttcgccgttt ttatcgagtc
     5881 cggcggcaag cccgacaggg ttgggcaaat ccaaacccat cagttttaca ggtttggtac
     5941 ggttgccggt tacgggaatc agacccaatt tataaaccat gttgagcgcg tcgagcgtga
     6001 agtggtgggc tttctcggca tcgagtgcaa acaggatgcg gcgggcaagt ggatacatga
     6061 cagggctttc tgcttcagat ggaaatgccg tcattttaac cgaaatcccg tcaaacatac
     6121 ggcacacagg tcaaacttga acgacaaaac ccgccgcacc caaaaatgta caaatcggca
     6181 aatattgata taatagtcat tagatagaaa actctattaa aagtcggtac aataccaccg
     6241 atttatttcc cttaaacaac ctgccgcaag gcataaagga acgactgata tgtcaaacat
     6301 cgaacaacaa gttaaaaaaa ttgttgctga acaactgggc gtaaacgaag ccgacgtgaa
     6361 aaacgaatct tctttccaag acgacttggg cgcggattct ttggacaccg tggagctggt
     6421 tatggctttg gaagaagcat tcggctgcga aatccccgac gaagatgccg aaaaaatcac
     6481 caccgtccaa ctggctatcg actacatcaa tgcccacaac ggctaaccgg tcgtcgcccg
     6541 acacaacagc ctctgctgca ccgcgcaata gaggcttttc ccttatatgg caaactgttt
     6601 gaacccctgc cgcaaattac agacggcatc tgcacgacag ccgcatatgc ccccattccg
     6661 acaaccaaca gcgaggttat catgagtcag agaagagtag tcattacagg cttaggtcag
     6721 gtttcccctg tcggcaacac tgtcgcagag gcttgggaca ccctgctcgc cggcaaaagc
     6781 ggcatcggcg cgattacccg ctttgacgca tccgacatca acagccgtgt cgccggcgaa
     6841 gtgcgcggtt tcgacatcgg acaatacatc agcgcgaaag aagcgcgccg gatggacgta
     6901 ttcatccact acggcattgc cgccgcattg caggcaatcg ccgattcggg cttggacgat
     6961 gtggaaaacc tcgacaaaga ccgcatcggc gtgaacatcg gttccggcat cggcggactg
     7021 cccagcatcg aggtcaccgg caaagccgta atcgaaggcg gcgcgcgcaa aatcaaccct
     7081 ttctttatcc ccggttcgct gatcaacctg atttccggac acgttaccat cctcaaaggc
     7141 taccgcggcc cgagctacgg gatggtttcc gcctgtacca ccggcgcgca cgccatcggc
     7201 aattccgccc gactgatcaa atacggcgac gcggacataa tggttgccgg cggcgcggaa
     7261 ggcgcaatca gcactttggg cgtgggcggt tttgccgcga tgaaagccct ctccacccgc
     7321 aacgacgacc ccgccaccgc ttcccgtccg tgggacaaag gccgcgacgg cttcgttatc
     7381 ggcgaaggcg cgggcatatt ggtgttggaa gaattggaac acgccaaaaa acgcggcgcg
     7441 aaaatctacg ccgaaatcgt cggcttcggc atgagttccg atgcttacca tatcaccgcg
     7501 ccgaacgaag aaggccccgc ccttgccgtt acccgcgcgc tgaaagatgc cggcatcaat
     7561 cccgaagacg tggattacgt caacgcgcac ggcacgtcca cccccttggg cgatgccaac
     7621 gaaaccaaag ccctcaaacg cgcgttcggc gaacacgcct acaaaaccgt cgtcagctcg
     7681 accaaatcca tgaccggcca cctgctcggc gcggcgggcg gcgtggaggc cgtgtacagc
     7741 attttggcga tacacgacgg caaaatcccg ccgaccatca acatttttga acaagacgtt
     7801 gaagccggct gcgatttgga ctactgcgcc aacgaagcgc gcgacgcgga aatcgacgtt
     7861 gccatttcca actccttcgg cttcggcggc accaacggca cgctggtctt caaacgcttc
     7921 aaaggctgat tccgcaaagc cgccgccgac atcgaaatgc cgtctgaaac cgtttcagac
     7981 ggcattttta tagtgattaa caaaaatcag gacaaggcgg cgagccgcag acagtacaaa
     8041 tagtacggaa ccgattcact tggtgcttca gcaccttaga gaatcgttct ctttgagcta
     8101 aggcggggca acgccgtacc ggtttaaagt taatccacta tatatcgtgg gacggttcgg
     8161 acacgcccga ctaagcgtcc cgacgcttgt cccacagagc gaacaagttg cccaataccg
     8221 tccccgaaac cgaatgccac acgcaggcga ccgccgccgc aaccgccgat tcggggttgc
     8281 ctgggaaaaa tttcgcgctc aatcctgttg ccaaaccggc attctgcacg ccgacttcga
     8341 ttgccaaggt gcgttttttt gccgtatcca taccaaacag cgcggcggcg taatagcctg
     8401 acacatagcc ggcgatattg tgtaccgcaa tcgccaacac cattaccaac gccgattcgg
     8461 caaaacggtg tccgtgaacc gaagccacgc cgccgacaat gcaggcaaat gccaataccg
     8521 ccacgcccgg cataacggca cggacatttt caaaccaatg ttttccgtgc agcaggatat
     8581 ttgccgccga acccagcacc accggcaaaa gcgtgaccag cagcataaac cggaacatcc
     8641 cccaaccgtc catatccacc gtctgaccga ccaggcaggt catccacaaa ggcgtaacgg
     8701 ccggagccag caccgtagac accgtcgtca taccgactga aaacgccaca tcgcctttgg
     8761 caaggaaact cataatgttg gacgacacgc cgcccggaca cgtccccacc aacaccagcc
     8821 ccaaagtcag ccccggcgaa aggtcgaaca gcttggcaat accgatggcg agcaacggca
     8881 tcacggtata ttgcgccgcc gcaccgataa acacatccaa aggacgctgc gccaaaatcc
     8941 ggtagtcctc cctgcccaaa gtcatcccca tacccagcat aatgatgccc agcaccaaga
     9001 cctgaacatc gcccttaacc cacgcaaacg aagccggtcc gataaacgca accgccgacg
     9061 caagcaaaat gaccaaagcc gtaaaccgcg tcaggttgcg gctcaaacca atcagaaaac
     9121 ccatcacaca cccctcccga aacggcgcac cttgcgccgg acattattac cgcccgtgca
     9181 aaaccgaccg acggccactc atcgtccccg ccccatttta ctaaccggaa ttaacagata
     9241 cagcacaaat attaacccga accgcaaacg cccatcaagc cctttctgac ggcatcggca
     9301 ggcataccgt tggctatatc caaagaatca ggaattattt agcccgaatc atccggttt
//
LOCUS       DAXISH010000070         9067 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.070, whole genome shotgun sequence.
ACCESSION   DAXISH010000070 DAXISH010000000
VERSION     DAXISH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9067
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.070"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            180..746
                     /locus_tag="ACFOV4_001804"
     CDS             180..746
                     /locus_tag="ACFOV4_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP family protein"
                     /protein_id="HFC7619759.1"
                     /translation="MGFYALLLIALGMSMDAFAVALAKGAAVRMPPRKIAATALVFGT
                     VEALTPLAGWVGGFYAKPFISEWDHWAAFVLLGGLGLKMLREGLSGGADDVREAKRES
                     WWLTVLTAFGTSIDSMIVGVGLAFMEVNIAFAAAVIGMATTVMVTVGLTAGRALGVLF
                     GKRAEFAGGLVLIAIGTWTLLSHLGLIQ"
     gene            complement(1190..3226)
                     /locus_tag="ACFOV4_001805"
     CDS             complement(1190..3226)
                     /locus_tag="ACFOV4_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family metallopeptidase"
                     /protein_id="HFC7619760.1"
                     /translation="MTDNALLHLGEEPRFDQIKTEDIKPALQTAIAEAREQIAAIKAQ
                     THTGWANTVEPLTGITERVGRIWGVVSHLNSVADTPELRAVYNELMPEITVFFTEIGQ
                     DIELYNRFKTIKNSPEFDTLSPAQKTKLNHDLRDFVLSGAELPPEQQAELAKLQTEGA
                     QLSAKFSQNVLDATDAFGIYFDDAAPLAGIPEDALAMFAAAAQSEGKTGYKIGLQIPH
                     YLAVIQYADNRELREQIYRAYVTRASELSDGGKFDNTANIDRTLANALQTAKLLGFKN
                     YAELSLATKMADTPEQVLNFLHDLACRAKPYAEKDLAEVKAFARESLNLADLQPWDLG
                     YASEKLREAKYAFSETEVKKYFPVGKVLNGLFAQIKKLYGIGFTEKTVPVWHKDVRYF
                     ELQQNGETIGGVYMDLYAREGKRGGAWMNDYKGRRRFSDGTLQLPTAYLVCNFAPPVG
                     GREARLSHDEILTLFHETGHGLHHLLTQVDELGVSGINGVEWDSVELPSQFMENFVWE
                     YNVLAQMSTHEETGEPLPKELFDKMLAAKNFQRGMFLVRQMEFALFDMMIYSEDDEGR
                     LKNWQQVLDSVRKEVAVVRPPEYNRFANSFGHIFAGGYSAGYYSYAWAEVLSADAYAA
                     FEESDDVAATGKRFWQEILAVGGSRSAAESFKAFRGREPRIDALLRHSGFDNAA"
     gene            complement(3314..4186)
                     /locus_tag="ACFOV4_001806"
     CDS             complement(3314..4186)
                     /locus_tag="ACFOV4_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HFC7619761.1"
                     /translation="MEIWNMLDTWLGAVPIRAEAVESVAVVAALLLARALLLNIHFKR
                     HPDFGIESKRRFLVASRNITLLLVLFSLAFIWSAQIQTLALSMFAVAAAVVVATKELI
                     MCLSGSILRSATQQYSVGDYIEINGLRGRVVDINLLNTLMMQVGPNPLVGQLAGTTVS
                     FPNSLLLSHPVRRDNILGDYVIHTVEIPVPIHLDSDEAVCRLKAVLEPLCAPYIPAIQ
                     RHLENVQAEKLFITPAARPRVTRVPYDDKAYRIIVRFASPVSKRLEIQQAVMDEFLRV
                     QYRLLNYPAGSETL"
     gene            4456..6846
                     /gene="gyrB"
                     /locus_tag="ACFOV4_001807"
     CDS             4456..6846
                     /gene="gyrB"
                     /locus_tag="ACFOV4_001807"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004283954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFC7619762.1"
                     /translation="MTEQKHEEYGADSIQVLEGLEAVRKRPGMYIGDTQDGSGLHHMV
                     FEVLDNAIDEALAGHCDKITVTIHADHSVSVADNGRGMPTGIHPKEGRSAAEVIMTVL
                     HAGGKFDNNSYKISGGLHGVGVSVVNALSDWVTLTIYRDGKEHFVRFVRGETEEPLKV
                     VGDSDKKGTTVRFLASAETFGNVEYSFDILAKRIRELSFLNNGVDIELTDERDGKHES
                     FALSGGVAGFVQYMNRKKTPLHEKIFYAFGEKDGMSVECAMQWNDSYQESVQCFTNNI
                     PQRDGGTHLTALRQVMTRTINSYIEANEVAKKAKVETAGDDMREGLTCVLSVKLPDPK
                     FSSQTKDKLVSGEIGPVVNEVISQALTDFLEENPAEAKIITGKIVDAARAREAARKAR
                     EITRRKGVMDGLGLPGKLADCQEKDPALSELYLVEGDSAGGSAMQGRDRKFQAILPLK
                     GKILNVEKARFEKMLASQEVAALITALGAGIGKEEFNAEKLRYHRIIIMTDADVDGAH
                     IRTLLLTFFYRQMPELVERGYIYIAQPPLYKAKYGKQERYLKDELEKDQWLLGLALEK
                     AKIISDGRTIEGAELADTAKQFLLAKTVIEQESRFVDELVLRAMLHASPIDLTSSENA
                     DKAVAELSGLLDEKEVALERIEGHEGHRFIKITRKLHGNVMVSYIEPKFLNSKAYQTL
                     TQTAAALKGMVGEGAKLYKGENGYDADSFETALDILMSVAQKGMSIQRYKGLGEMNPE
                     QLWETTMDPAVRRLLKVRIEDAIAADEVFVTLMGDEVEPRRAFIENNALIAQNIDA"
     gene            6943..8328
                     /locus_tag="ACFOV4_001808"
     CDS             6943..8328
                     /locus_tag="ACFOV4_001808"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HFC7619763.1"
                     /translation="MISIFDIFKIGIGPSSSHTVGPMKAAAAFAAGLDAQAVRIVIDI
                     YGSLALTGYGHGTFDALMLGLEGSLPHDIPLAGIPERLERIRTQHILRLNGQEIRFIP
                     DRDLNILGNQVLPKHPNSLRFTAYASDGTVLNEQVYYSVGGGFVVTEEDFDRQAETEK
                     AVPYPYTSCAELLARCRLNRLDISEVVLANEAALAGCGEAEIRRRVAGVADVMEGCIK
                     RGLAADGELPGGLNVRRRAPQLAAKLKVLRETEIVNTQLWPMVYAMAVNEENAAGGRV
                     VTALTNGAAGIIPAVLHYFRKFNPHATQERVENFLLTAGAIGILYKTNASISGADVGC
                     QGEVGVACSMAAGAYAEVIGGTPKQVENAAEMAMEHHLGLTCDPVGGLVQIPCIERNG
                     IAAEKALKLGTLALLEDGTDKKVSLDEVIRTMLQTGRDMKSTYKETSLAGLAATLRKK
                     AVPVSVRVVEC"
     gene            complement(8399..8497)
                     /locus_tag="ACFOV4_001809"
     CDS             complement(8399..8497)
                     /locus_tag="ACFOV4_001809"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="eamA-like transporter family protein"
                     /protein_id="HFC7619764.1"
                     /translation="MAVVFLDERPNTQEWIGLGLVTAGVLTLALKR"
     gene            complement(8632..>9067)
                     /locus_tag="ACFOV4_001810"
     CDS             complement(8632..>9067)
                     /locus_tag="ACFOV4_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619765.1"
                     /translation="VKEYQPPVGIFLFVCFEKCLFPDFAIPIRFCAVRCVLARTCSKS
                     DVVPVFEALIRDADFQYIFLSYNNEGLMSVGQVREIFECFGKYNLVQTEYRRFKADKT
                     ENRNHKANSIFEYLHILEKTFYSGLTKTSTALPRLSSKRTIL"
BASE COUNT         2050 a         2431 c         2563 g         2023 t
ORIGIN      
        1 ccgtttttcc cgataagttt ccgcaccgac aactctggat tcccgcctgc gcgggaatga
       61 cgggatttct gtttttgatt ttttgttttt gcgggaatga cgggatgtgg gttttcgtgc
      121 ggcgtttttg catttttttg cttttgctat aatccgccct ttttgaggac gggtgcggta
      181 tgggttttta tgctttgctc ttgattgcgc tggggatgtc gatggatgcg tttgccgtcg
      241 cattggcaaa gggtgcggcg gtcagaatgc ctccgcgcaa aattgcggca acggctttgg
      301 tgttcggcac ggttgaagcg ctcacgccgc tggcaggctg ggtgggcggt ttttatgcca
      361 agccgtttat cagcgaatgg gaccattggg cggctttcgt cctgctgggc gggctgggtc
      421 tgaagatgtt gcgtgagggc ttgtccggcg gggcggacga tgtgcgcgaa gccaaacggg
      481 aaagctggtg gttgacggtt ctgactgctt ttggaaccag tattgattcc atgatagtcg
      541 gggtgggctt ggcgtttatg gaggtaaaca tcgcctttgc cgccgccgtc atcggcatgg
      601 cgacgacggt gatggttacg gtcgggctga cggcgggaag ggctttgggc gtattgttcg
      661 gcaaacgcgc cgagtttgcc ggaggtttgg tgttgattgc catcggtaca tggacgctct
      721 tgtcgcattt gggtttgatt caatgatgtc ggaaaatata gtggattaac aaaaaccagt
      781 acgtcgttgc ctcgccttgg ctcaaagaga acgattctct aaggtgctga agcaccaagt
      841 gaatcggttc cgtactattt gtactgtctg cggcttcgtc accttgccct gatttttgtt
      901 aatccactat aaaatgccgt ctgaagcgtt gtttgaccgt ttcagacggc atttttatca
      961 aattcaaaaa tattccgtca ttcccgcgaa agcgggaatc tagaacgtaa aatctaaaga
     1021 aaccgtttta tccgataagt ttccgcaccg acagacctgg attcccgcct gcgcgggaat
     1081 gacgggattt tggcttactg tttttgtgaa aatggcgaaa ccgtgcaaat gctgatgccg
     1141 tctgaaacac tgtttgattg tttcagacgg cattttttgt tcacatcgat caagccgcgt
     1201 tgtcgaaacc gctgtggcgc aagagtgcgt ctatgcgcgg ttcgcgtccg cggaaggctt
     1261 tgaaggattc tgccgcgctg cgcgatccgc cgacggcgag gatttcctgc caaaagcgtt
     1321 tgcctgtggc ggcgacatcg tcgctttctt caaaggcggc gtatgcgtcc gcgctcaata
     1381 cttccgccca tgcgtagctg taatagcctg cggagtagcc gccggcgaag atgtggccga
     1441 agctgttggc gaagcggttg tattcgggcg gtcggacgac ggcgacttct ttgcgcacgc
     1501 tgtctaaaac ctgttgccag tttttcagac ggccttcgtc gtcttcgctg taaatcatca
     1561 tatcgaagag ggcgaactcc atctggcgga cgaggaacat tccgcgttgg aagtttttgg
     1621 cggcgagcat tttgtcgaag agttctttcg gcaggggctc gccggtttct tcgtgggtgg
     1681 acatttgcgc caatacattg tattcccaaa cgaaattttc cataaactgg ctgggcagtt
     1741 cgaccgagtc ccattctacg ccgttgatgc cggacacgcc cagttcgtcc acttgggtaa
     1801 gcaggtggtg caggccgtgg ccggtttcgt ggaagagggt gaggatttcg tcgtggctca
     1861 ggcgggcttc cctgccgccg acgggtgggg cgaagttgca gacgaggtag gcggtgggca
     1921 gttgcagcgt gccgtctgaa aaacggcggc gacctttgta gtcgttcatc cacgcgccgc
     1981 cgcgtttgcc ttcgcgggcg tagaggtcca tatagacgcc gcctatggtt tcgccgtttt
     2041 gttgcaattc aaaatagcgc acgtctttgt gccagacggg gacggttttt tcggtaaatc
     2101 cgatgccgta gagttttttg atttgggcaa acagtccgtt taatactttg ccgacgggga
     2161 agtatttttt gacttcggtt tcgctgaacg cgtatttggc ttcgcgcagt ttttcgctgg
     2221 cgtagcccaa gtcccacggt tgcaaatcgg cgaggttcag gctttcgcgg gcgaaggctt
     2281 tgacttcggc gaggtctttt tcggcgtagg gtttggcgcg gcaggcgagg tcgtgcagga
     2341 agtttaaaac ttgttcgggg gtgtccgcca ttttggttgc cagcgacaat tcggcgtagt
     2401 ttttgaagcc gagcagtttg gcggtttgca gggcgtttgc gagcgtgcgg tcgatgttgg
     2461 cggtgttgtc gaatttgccg ccgtctgaaa gttcgctggc gcgggtaacg taggcgcggt
     2521 agatttgttc gcgcagttcg cggttgtcgg cgtattggat gacggcgagg tagtgcggaa
     2581 tctgcaaacc gattttgtag cctgttttac cttcgctttg cgcggcagcg gcaaacatgg
     2641 cgagcgcgtc ttcgggaatg ccggcaagcg gtgcagcatc gtcaaagtaa atgccgaacg
     2701 cgtcggtcgc gtctaggacg ttttgggaga atttggcgga aagttgcgcg ccttcggttt
     2761 gcagttttgc cagttctgcc tgctgttcgg gcggcagttc cgcgccgctg aggacgaaat
     2821 cgcgcagatc gtggttgagt ttggtttttt gcgcggggga gagggtgtcg aactcggggg
     2881 agtttttgat ggttttgaag cggttgtaca gctcgatgtc ttgtccgatt tcggtgaaga
     2941 agacggtgat ttcgggcatc agttcgttat agacggcgcg cagttcgggc gtgtcggcga
     3001 cggagttgag gtgcgacacc acgccccaaa tcctgccgac gcgttcggtg atgccggtca
     3061 ggggttcgac agtgtttgcc cagccggtgt gcgtttgggc tttgatggcg gcgatttgtt
     3121 cgcgcgcttc ggcgatggcg gtttgcaggg cgggtttgat gtcttcggtt ttgatttgat
     3181 caaaacgggg ttcttcgccc aaatggagca gtgcgttgtc agtcataaga tgggtttcct
     3241 ttgcgtgttg tgcttcagac agcatatcgg caatatgccg tctgaagccg gaaatggggt
     3301 cggtcgggga aagttaaagt gtttcggagc cggcggggta atttaacagg cggtattgta
     3361 cgcgcaaaaa ttcgtccata accgcctgtt ggatttccag ccgctttgaa acgggggagg
     3421 cgaagcggac gatgatgcgg tatgccttgt catcgtacgg cacgcgggta acgcgcggtc
     3481 tggcggcggg cgtgataaac agtttttccg cctgcacgtt ttccaaatgc cgttggatgg
     3541 cggggatgta gggcgcgcac aagggctcga gtacggcttt cagacggcat acggcttcat
     3601 ccgaatccaa atggatgggg acggggattt cgaccgtatg gatgacgtag tcgcccaaaa
     3661 tattgtcgcg gcgcacggga tggctcaaca acaggctgtt ggggaaagaa acggtggttc
     3721 ccgcaagctg tccgaccagg gggttcggac cgacctgcat catcagcgtg ttcaacaggt
     3781 tgatgtcgac cacgcgcccg cgcaggccgt tgatttcgat atagtcgccg accgagtatt
     3841 gctgggtggc agaccttaaa atactgcccg acagacacat aatcagttcc tttgtcgcca
     3901 cgacgaccgc cgccgccacc gcaaacatcg acaaagccag cgtttggatt tgcgccgacc
     3961 agataaatgc cagcgaaaac agcaccaaaa gcagcgttat attgcggctg gcaaccaaaa
     4021 accgccgctt gctttcgatg ccgaaatccg gatgccgttt gaagtggata ttcaacagaa
     4081 gggcgcgcgc cagcagcaaa gccgcgacca ccgccacgga ttcgaccgcc tccgcacgta
     4141 tcgggacggc accgagccaa gtgtccaaca tattccatat ttccatttcc gcgcccctgt
     4201 ccgaaaagta tagggtgtag attttagtgg caaaaaaacg cttttgccac tttacgggac
     4261 aatccccgac ctgatgccgg aggcaaacgt accgtttcat cttttcccgg cggcacactg
     4321 atgcggataa cgctgaatta ggcggcaaaa tcggctataa tacacaatta tatatgccgt
     4381 cccgcccgct ttttctacaa ggtgcggact tgttttggcg gcatcgcaaa atcttttcaa
     4441 aatccggcaa aaaatatgac tgaacaaaaa cacgaagaat acggcgccga cagcattcag
     4501 gtgctcgaag gcttggaagc ggtacgcaaa cgccccggta tgtacatcgg cgacacgcag
     4561 gacggcagcg gcctgcacca catggtgttc gaagtattgg acaacgccat tgacgaagca
     4621 ctcgccggac attgcgacaa aatcaccgtt accatccacg ccgaccattc cgtcagcgtc
     4681 gccgacaacg ggcgcggtat gcccaccggc atccacccga aagaaggacg ctccgccgcc
     4741 gaagtcatca tgaccgtatt gcacgcgggc ggtaaattcg acaacaacag ctacaaaatc
     4801 tccggcggcc tgcacggcgt gggcgtgtcc gtcgtcaacg cgctgtccga ctgggtaacg
     4861 ctgaccatct accgcgacgg caaagaacac ttcgtccgct tcgtgcgcgg cgaaaccgaa
     4921 gagccgttga aggttgtcgg cgattccgat aaaaaaggca cgaccgtgcg cttcctcgcc
     4981 agtgcggaaa ccttcggcaa cgtcgaatac agcttcgaca tcctcgccaa acgcatccgc
     5041 gaactttcgt tcctgaacaa cggcgtggac atcgaattga ccgacgagcg cgacggcaaa
     5101 cacgaaagct tcgccctttc cggcggcgtg gctggattcg tgcaatacat gaaccgcaaa
     5161 aaaacgccct tgcacgaaaa aatcttctac gcgttcggcg agaaagacgg catgagcgtc
     5221 gaatgcgcaa tgcaatggaa cgacagctat caggaaagcg tgcagtgctt caccaacaac
     5281 atccctcagc gcgacggcgg tacgcacctg accgcgttgc gccaagtgat gacgcgcacc
     5341 atcaacagct acatcgaagc caacgaagtc gccaaaaaag ccaaagtgga aaccgccggc
     5401 gacgatatgc gcgaaggttt gacctgcgtg ttgtccgtca aactgcccga ccccaaattt
     5461 tcgtcccaaa ccaaagacaa actggtttcc ggcgaaatcg gtcccgtcgt caacgaagtc
     5521 atcagccaag ccctgaccga cttcctcgaa gaaaaccctg ccgaagccaa aatcatcacc
     5581 ggcaaaatcg tcgatgccgc ccgcgcgcgc gaagccgccc gcaaagcccg cgaaatcacc
     5641 cgccgcaaag gcgtaatgga cggcttgggg ctacccggta aactcgccga ctgccaagaa
     5701 aaagaccccg cattgtcaga actttatctg gtcgagggcg attctgcagg cggttccgcc
     5761 atgcaggggc gcgaccgcaa attccaagcg attttgccgc ttaagggcaa gattttgaac
     5821 gtcgaaaaag cgcgctttga aaaaatgctc gccagtcagg aagtagccgc tttgattacc
     5881 gcgttgggcg cgggcatcgg caaagaagaa ttcaatgccg agaagctgcg ttaccaccgc
     5941 atcattatca tgaccgatgc cgatgtggac ggcgcgcata tccgcacctt gcttttgacc
     6001 ttcttctacc gccaaatgcc cgaactggtc gagcgcggct acatctatat cgcccagccg
     6061 cctttgtata aagcgaaata cggcaaacag gaacgttacc tcaaggacga gttggaaaaa
     6121 gaccaatggc tgctcggtct tgccttggaa aaagccaaaa tcatttcaga cggccgcacc
     6181 atcgaaggcg cagaacttgc cgacaccgcc aaacaattcc tgttggcaaa aaccgtcatc
     6241 gaacaggaaa gccgcttcgt agacgaactc gtcctgcgcg ccatgctaca cgcgtcgccc
     6301 attgatttga cgtcgtctga aaacgccgat aaagccgttg ccgaactttc cggtctgctt
     6361 gacgaaaaag aagtcgccct cgaacgcatc gaaggtcatg aaggacaccg gttcatcaaa
     6421 atcacgcgca agctgcacgg caacgtcatg gtcagctaca tcgaacccaa gttcctcaac
     6481 agcaaagcct accaaaccct cacccaaacc gccgccgcgc tcaaaggcat ggtcggcgag
     6541 ggtgccaagc tttacaaagg cgaaaacggg tacgacgcgg acagctttga aaccgctttg
     6601 gacatcttga tgagcgttgc ccaaaaaggt atgtccatcc aacgatacaa aggcttgggc
     6661 gagatgaacc ccgagcagct gtgggaaacc acgatggatc ccgccgtgcg ccgcctgttg
     6721 aaagtgcgca tcgaagatgc cattgccgcc gacgaagtgt tcgttacgct gatgggcgac
     6781 gaggtcgagc cgcgccgtgc ctttatcgaa aacaacgcgc tgattgccca aaatatcgac
     6841 gcataagtgc cgttttaaaa aaggagacgg gcatcgtgcc gcgtctcctt tttggttggt
     6901 caaacggaac ctgtgccgtc tgaaaaaccg tcggagcaaa atatgatcag cattttcgat
     6961 attttcaaaa tcggtatcgg gccttccagt tcgcatacgg tcggcccgat gaaggcagcc
     7021 gccgcctttg cggcaggttt ggatgcacag gctgttcgca tcgtcatcga catttacggc
     7081 tcgctcgcac tgaccggata cggacacggt acatttgacg cgctgatgct cggtttggaa
     7141 ggcagcctgc cgcacgacat cccgcttgcc ggcattcccg aacgcctcga acgcatccgc
     7201 acgcagcaca tcctccggct caacgggcaa gaaatccgct tcatccccga ccgcgacctg
     7261 aacatactcg gcaatcaagt gctgcccaaa caccccaaca gcctgcgttt taccgcctat
     7321 gcttcagacg gcacggtatt gaatgaacag gtttattatt cggtcggcgg cggctttgtc
     7381 gttaccgaag aagattttga ccggcaggcg gaaacggaaa aagccgttcc ctatccctat
     7441 accagttgcg ccgaactgct tgcccgatgc cgtctgaacc ggctcgacat ctccgaagtc
     7501 gtgttggcaa acgaagccgc gcttgccgga tgcggcgaag ccgaaatccg ccgccgcgtt
     7561 gccggcgttg ccgatgtgat ggaaggctgc atcaaacgcg gtttggcggc agacggcgag
     7621 ctgcccggcg gattgaacgt ccgccgccgc gccccgcagc ttgccgccaa gctcaaagtc
     7681 ctgcgcgaaa ccgaaatcgt caacacccag ctctggccga tggtgtacgc catggcggtc
     7741 aacgaagaaa acgccgccgg cggacgcgtc gttaccgcac tgaccaacgg cgcggcaggc
     7801 atcattcccg ccgtattgca ctatttccgc aagttcaatc cgcacgccac acaggaacgc
     7861 gtcgaaaact tcctgctcac cgcaggcgca atcggcatcc tctacaagac caacgcctcc
     7921 atttccggtg cggatgtcgg ctgtcagggc gaagtcggcg tagcgtgttc gatggcggcg
     7981 ggcgcatacg ccgaagtcat cggcggcacg cccaaacaag tggaaaacgc cgccgaaatg
     8041 gcgatggaac accatttggg gctgacttgc gaccccgtcg gcggactggt gcaaatcccc
     8101 tgcatcgagc gcaacggcat cgccgccgaa aaagccctca aactcggcac gctcgcgctt
     8161 ttggaagacg gcacggacaa aaaagtctcg ctcgacgaag tcatccgaac catgttacag
     8221 acagggcgcg acatgaagtc cacctacaaa gaaacctcgc ttgccggact cgccgccacg
     8281 ctccggaaaa aagccgtccc cgtatccgtg cgcgtggtcg agtgctgagg atggacagaa
     8341 acgaaaatgc cgtctgaaaa cagtttttta gacggcattt catttatttc ttgcggcttt
     8401 accgtttcag tgccagcgtc aacacgcccg ccgtaaccag ccccaagcct atccattcct
     8461 gcgtgttcgg gcgttcgtct aagaaaacca ccgccatcag gaatgcaaac cggcgttgtt
     8521 tgcagcatcc ggcaagaatt tttatagtgg attaacaaaa atcaggacaa ggcgacgaag
     8581 ccgcagacag tacaaatagt acggaaccga ttcacttggt gcttcagcac cttagagaat
     8641 cgttctcttt gagctaaggc gaggcaacgc cgtactggtt tttgttaatc cactataaaa
     8701 ggtcttttct aaaatatgca gatattcgaa tatcgaattt gccttatgat tacggttttc
     8761 tgtcttatct gccttaaaac gccggtattc cgtttgaacc aaattatatt tgccgaaaca
     8821 ctcaaaaatc tcccttacct gcccgacaga catcaagcct tcgttgttgt agctgagaaa
     8881 aatatattga aagtccgcat ccctaatcaa agcctcaaat accggaacca catccgattt
     8941 tgagcaagtc cgcgctaaaa cacatcgtac agcgcaaaac cggatgggaa tggcaaaatc
     9001 cggaaacaaa catttttcaa agcatacaaa caaaaaaata ccaaccggag gttggtattc
     9061 cttaact
//
LOCUS       DAXISH010000071         8970 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.071, whole genome shotgun sequence.
ACCESSION   DAXISH010000071 DAXISH010000000
VERSION     DAXISH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8970
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.071"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(391..825)
                     /locus_tag="ACFOV4_001811"
     CDS             complement(391..825)
                     /locus_tag="ACFOV4_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ExbD/TolR family protein"
                     /protein_id="HFC7619766.1"
                     /translation="MAFGSMNSGDDSPMSDINVTPLVDVMLVLLIVFMITMPVLTHSI
                     PLELPTASEQTNKQDKQPKDPLRLTIDANGGYYVGGDSASKVEIGEVESRLKAAKEQN
                     ENVIVAIAADKAVEYDYVNKALEAARQAGITKIGFVTETKAQ"
     gene            complement(828..1490)
                     /gene="exbB"
                     /locus_tag="ACFOV4_001812"
     CDS             complement(828..1490)
                     /gene="exbB"
                     /locus_tag="ACFOV4_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-system energizer ExbB"
                     /protein_id="HFC7619767.1"
                     /translation="MNLKLVFESGDPVLIGVFVLMLLMSIVTWCLVVLRCIKLYRARK
                     GNAAVKRHMRDTLSLNDAVEKVRAVDAPLSKLAQEALQSYRNYRRNEASELAQALPLN
                     EYLVIQIRNSMAQIMRRFDYGMTALASIGATAPFIGLFGTVWGIYHALINIGQSGQMS
                     IAAVAGPIGEALVATAAGLFVAIPAVLAYNFLNRGTKILTQDLDAMAHDLHVRLLNQK
                     DS"
     gene            complement(1556..2398)
                     /locus_tag="ACFOV4_001813"
     CDS             complement(1556..2398)
                     /locus_tag="ACFOV4_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0031992 - energy transducer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HFC7619768.1"
                     /translation="MDKERILTPAVVFSVALLHLAMVALLWQAHKLPVIESGNVIEFV
                     DLGDFGGGDGAPEGAGAPAAPEPQPEPEPPKPVEPPKPVLKPVVTKKADADIQQPKEE
                     PKPEEKPKPEEKPKPEPKPEAKPVPKPAEKPVEKPSEKPAEHPSNASAKADSEQGNGE
                     DKGTGTKGDGTGRGEGSGKGSGGVKGEHGEGAGSSKGNPLRANGSIPRPAYPTLSMEN
                     DEQGTVVLSVLVSPGGHVESVKIVKSSGFSRLDNAARKAAQNGHFQANAWTEFKVPVK
                     FELN"
     gene            2653..3291
                     /locus_tag="ACFOV4_001814"
     CDS             2653..3291
                     /locus_tag="ACFOV4_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HFC7619769.1"
                     /translation="MFQNFDLGVFLLAVLPVLLAITVREVARGYTARYWGDNTAEQYG
                     RLTLNPLPHIDLVGTIIVPLLTLMFTPFLFGWARPIPIDSRNFRNPRLAWRCVAASGP
                     LSNLAMAVLWGVVLVLTPYVGGAYQMPLAQMANYGILINAILFALNIIPILPWDGGIF
                     IDTFLSAKYSQAFRKIEPYGTWIILLLMLTGVLGAFIAPIVRLVIAFVQMFV"
     gene            complement(3743..4543)
                     /locus_tag="ACFOV4_001815"
     CDS             complement(3743..4543)
                     /locus_tag="ACFOV4_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HFC7619770.1"
                     /translation="MKKTIFNITKMDCPSEEQLIRMRLKDVSDIYELQFDIAGRCLTV
                     YHDNQDTTILQVLEPLNFDSHIISTEVIVDKIVFNKPDEHLEKRLLYQVLMINFVFFI
                     IECSVGIFANSMGLIADSLDMLADSFVYILALSAIGMTMAYKKRVAFLAGITQIILAL
                     FGVIEVIRRFIGAEQLPNYQLMIGTAFLALIANWLCLYLLSKNQNKEIHIKASMIFTS
                     NDIIINIGVIAAGALTLLTHSSYPDLIIGMIVFVIVLFGARNILKLAK"
     gene            complement(4679..5182)
                     /locus_tag="ACFOV4_001816"
     CDS             complement(4679..5182)
                     /locus_tag="ACFOV4_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619771.1"
                     /translation="MDAFDFFMQGNFKKIATEQGLDRKYFIFQYIVCNLSAISSFCLM
                     KIIHTYTILYILIAVIGIINGFLLRSKVLSIVKNKQKFLSDMFPLEMPFFFVEYKIPI
                     LARFLNRGMKWLYLPSFFCLVAICFSIYILNEEGGWMPYFACYWFGLCYPVSTYYVFL
                     SRDYKHI"
     gene            complement(5519..6160)
                     /locus_tag="ACFOV4_001817"
     CDS             complement(5519..6160)
                     /locus_tag="ACFOV4_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GrxB family glutaredoxin"
                     /protein_id="HFC7619772.1"
                     /translation="MKLYIYDHCPFCVRARMAAGLFGADVEEAVLANDDEATPIGMIG
                     AKQVPVLQKEDGSFMGESLDIVRHFDREDRLKDEVRPEIRAWLDKVGGYNDKLVQPRV
                     IKIGLPEFATPEAVKYFTDKKEKSIGSFSANLNKTAQYLERINADLQELENLMDGASD
                     GINGGIGMEDILVFPVLRNLTVVRGIEWPQKVMGYLMTMSEKSGVPLYFDRAL"
     gene            6488..8701
                     /locus_tag="ACFOV4_001818"
     CDS             6488..8701
                     /locus_tag="ACFOV4_001818"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFC7619773.1"
                     /translation="MTAISPIQDTQSATLQELREWFDSYCAALPDNDKKLVLAARSLA
                     EAHYPADAVTPYGEPLSDHFLGAAQMVDELDLLPDAVAATLLADIGRYVPDWNLLVSE
                     RCNSTVAELVKGVDEVQKLTHFARVDSLATPEERAQQAETMRKMLLAMVTDIRVVLIK
                     LAMRTRTLQFLSNAPDSPEKRAVAKETLDIFAPLANRLGVWQLKWQLEDLGFRHQEPE
                     KYREIALLLDEKRTERLEYIENFLNILRTELKKYNIHFEVAGRPKHIYSIYKKMVKKK
                     LTFDGLFDIRAVRILVDTIPECYTTLGIVHSLWQPIPGEFDDYIANPKGNGYKSLHTV
                     IVGPEDKGVEVQIRTFDMHQFNEFGVAAHWRYKEGGKGDSAYEQKIAWLRQLLDWREN
                     MAESGKEDLAAAFKTELFNDTIYVLTPHGKVLSLPTGATPIDFAYALHSSIGDRCRGA
                     KVEGQIVPLSTPLENGQRVEIITAKEGHPSVNWLYEGWVKSNKAIGKIRAYIRQQNAD
                     TVREEGRVQLDKQLAKLTPKPNLQELAENLGYKKPEDLYTAVGQGEISNRAIQKACGT
                     LNEPPPVPVSETTIVKQSKIKKGGKNGVLIDGEDGLMTTLAKCCKPAPPDDIVGFVTR
                     DRGISVHRKTCPSFRHLAEHAPEKVLDASWAALQEGQVFAVDIEIRAQDRSGLLRDVS
                     DALARHKLNVTAVQTQSRDLEASMRFTLEVKQVNDLPRVLASLGDVKGVLSVTRL"
BASE COUNT         2420 a         2379 c         1934 g         2237 t
ORIGIN      
        1 ggtatagcgg attaacaaaa accagtacgg cgttgcctcg ccttaactca aagagaacga
       61 ttctctaagg tgctgaagca ccaagtgaat cggttccgta ctatttgtac tgtctacggc
      121 ttcgttgcct tgtcctgatt tttgttaatc cactataaaa attagaaatg cacattttca
      181 ttattctcgc gcaggcagga ctccagactt acccatttca gtaatgtttg aaaataaaag
      241 aaaaatcaga tgtttgtatt cccgcctgcg cagaaatgga gacggtgctc tgtcgtctca
      301 tttttgtttt aatcaactat atatagctga ttaaacataa gaaatgccgt ctgaaagact
      361 ttcagacggc attcgttcaa gcgtcgaact ttattgcgcc ttggtttcgg ttacaaaacc
      421 gattttggtg attcctgcct gacgggcggc ttctaaagct ttgtttacat aatcgtattc
      481 caccgccttg tctgccgcaa tcgccacaat cacgttttca ttctgctcct tggcggcttt
      541 cagacggctt tccacttccc cgatttccac tttgcttgca gaatccccgc cgacataata
      601 gccgccgttc gcatcaatcg tcaggcgcag ggggtcttta ggctgtttgt cctgcttgtt
      661 tgtctgctcg gacgcggtcg gcagttccaa agggatggaa tgcgtcagca ccggcatagt
      721 aatcataaac acaatcagca acaccagcat cacgtccacc aacggcgtaa cgttgatgtc
      781 ggacatcgga gaatcgtcgc cggaattcat cgaaccaaat gccataatca gctatccttt
      841 tgattaagca ggcggacgtg caaatcgtgc gccatcgcat ccaaatcctg ggtcagtatt
      901 tttgtgccgc gattgaggaa gttgtatgcc aacaccgccg gaatcgccac gaacaaaccc
      961 gccgccgtcg ccaccagtgc ctcgccaatc gggccggcaa ccgccgcaat actcatctgc
     1021 ccgctttgcc cgatattgat cagggcgtgg taaatccccc aaaccgtgcc gaacagcccg
     1081 ataaacggcg cggtcgcgcc gatggaggca agcgcggtca tcccgtaatc aaaccggcgc
     1141 ataatctgcg ccatactgtt gcggatttga atgaccaaat actcgttcaa cggcaaagcc
     1201 tgcgccagtt cggacgcttc gtttcggcgg tagttgcggt aagactgcaa tgcctcttgc
     1261 gccagtttgg acaaaggcgc atcgacggcg cgcacttttt cgaccgcgtc gttcagcgac
     1321 aaagtatcgc gcatatgccg tttgacggcg gcattccctt tgcgcgcccg atacagcttg
     1381 atgcagcgca agacaaccaa acaccacgtt acgatactca tcaacagcat caacacaaac
     1441 acaccgatca ggacgggatc gcccgattca aatactaatt tcaaattcat aatgattcca
     1501 acactgaaaa aaccaatcaa acatccaagc tgccgcaaac cgctgcggca accgcctaat
     1561 tcaattcaaa cttgacgggg actttaaact ccgtccaggc attggcttga aaatgcccgt
     1621 tttgcgccgc cttgcgtgcc gcattgtcca accgagaaaa accactgctt ttcacgattt
     1681 taacggactc gacatgaccg cccggagaaa ccaaaacgct caaaacaacc gtaccctgct
     1741 cgtcattctc catagaaagc gtgggataag ccgggcgcgg aatgctgccg ttggcgcgta
     1801 aaggattgcc tttgctgctg ccggctcctt ccccgtgttc gcctttgaca ccgccgctac
     1861 ctttaccgct gccttctccg cgccccgttc cgtctccttt ggtaccggtt cccttatctt
     1921 ccccattacc ctgctcgctg tctgctttgg cagaagcatt gctgggatgt tcggcaggtt
     1981 tttcagacgg cttctcgacc ggtttttccg ccggtttcgg gacaggcttc gcttccggct
     2041 taggctctgg tttcggtttt tcttcgggtt tcggcttttc ttcaggtttc ggctcttcct
     2101 taggctgctg aatatccgca tccgcctttt tcgtaaccac cggcttcaaa accggcttgg
     2161 gcggctcgac aggtttgggc ggctcaggct caggttgcgg ctcaggcgca gcaggcgcac
     2221 ctgcgccttc gggtgcaccg tcccctccgc caaaatcacc caaatcgaca aattcgataa
     2281 catttcctga ctctatcacg ggcagcttgt gcgcctgcca gagcaatgcc accattgcca
     2341 aatgcagcag tgcgacggaa aacacgactg cgggggttaa aattcgttct ttatccataa
     2401 ttcgggcata ataatagcaa caattcctat ttgcaaccta tttttacaat ttttggtcat
     2461 atgaatgtct gttccgttca caggcaaacc gtgtttaaac gctgtattac agcaaatcat
     2521 cagataacgg gccggcagaa aaaatgattc cgtctgattt cttattccaa taaaatcagg
     2581 ttagatgata tattgccgct tctgtctgtc agccgtttcg ggctgcacac cacatctgtt
     2641 caaaggaaaa ccatgtttca aaattttgat ttgggcgtgt ttctgcttgc cgtcctgccc
     2701 gtgctgctcg ccattaccgt cagggaggtg gcgcgcggct atacggcgcg ctactgggga
     2761 gacaacactg ccgaacaata cggcaggctg acactgaacc ccctgcccca tatcgatttg
     2821 gtcggcacaa tcatcgtacc gctgcttact ttgatgttca cgcccttcct gttcggctgg
     2881 gcgcgtccga ttcctatcga ttcgcgcaac ttccgcaacc cgcgccttgc ctggcgttgc
     2941 gttgccgcgt ccggcccgct gtcgaatctg gcgatggctg ttctgtgggg cgtggttttg
     3001 gtgctgactc cgtatgtcgg tggggcgtat cagatgccgt tggctcaaat ggcaaactac
     3061 ggtattctga tcaatgcgat tctgttcgcg ctcaacatca tccccatcct gccttgggac
     3121 ggcggcattt tcatcgacac cttcctgtcg gcgaaatatt cgcaagcgtt ccgcaaaatc
     3181 gaaccttatg ggacgtggat tatcctactg ctgatgctga ccggggtttt gggtgcgttt
     3241 attgcaccga ttgtgcggct ggtgattgcg tttgtgcaga tgttcgtctg actggctttc
     3301 agacggcata aacgctccag aaaacgcggc aggacatatt gccctgccgc gttttcctgt
     3361 agtgtaatct tatttttttc atcattatta gaaccaagtt gcatgataat acctttcatt
     3421 aactgaaaca ctgattaaga aactccagtc tgtctaatga tgaggttttc acatcgccaa
     3481 aacttgccaa tcaaatgctg gatttattgc cgtctgagat ttggtcaaat ccaaaggcga
     3541 cattcttaga ccctgtgtgt aaatcagggg tatttttgcg tgaaatcgtc aaacgcttgg
     3601 atgaaggctt gaccaatcaa ataccagata aacaaactcg cattaaccac attttaaaaa
     3661 atcaagtttt tggaagtact gccacgtatg taggtagctt tgaccgatat ttgcataaaa
     3721 actcctttgc tggtgaaagg aattattttg ccaattttaa aatatttctg gcaccaaata
     3781 gtacaatgac aaagacaatc atgccaatga ttaaatcagg atagctagaa tgagtcaata
     3841 acgtcaatgc tcccgccgct atcacaccga tattgatgat aatgtcattg gatgtaaaaa
     3901 tcatgctggc tttgatatgg atttctttat tttgattttt gctcagtaga tataagcaca
     3961 gccagtttgc aatcaatgcc aaaaatgccg tgccaatcat cagttgataa ttgggcagct
     4021 gctcagcacc gataaaacgc ctaatcactt ctatcacccc aaataacgcc aatattatct
     4081 gcgttatccc cgccaaaaat gccacacgtt ttttatacgc catcgtcata ccaatggctg
     4141 atagcgccaa tatatagaca aagctgtccg ccagcatatc tagactatca gcaatcagcc
     4201 ccatagaatt agcaaaaata ccaaccgaac actctatgat aaaaaacaca aagttaatca
     4261 tgagcacttg atataataat cttttttcta agtgctcatc aggcttgtta aacactatct
     4321 tatcaacaat cacttcggtg gaaatgatat gactatcaaa attaagcggt tcaagtactt
     4381 gtaaaatcgt tgtatcttga ttatcgtgat agacggttaa gcaccgccca gcaatatcaa
     4441 actgtaattc ataaatatca gacacatctt ttaaacgcat gcgaatgagc tgttcttcgg
     4501 acgggcagtc cattttggta atgttaaaaa tggtcttttt catctattta gttccttgtt
     4561 ttgatcaggt tggctcaaat aaatctgtgt ttatattgct gcttggtaat ttttggatgg
     4621 tttgagtaaa ttgattaggt taaaatttac ctttggaagt accgccacgc ataatagttt
     4681 agatatgttt ataatctctg gataaaaaaa cgtaataagt gcttactgga taacaaagtc
     4741 caaaccaata gcaggcaaaa taaggcatcc accccccttc ttcattaagg atatatattg
     4801 agaaacaaat cgcaactaaa cagaaaaaac ttgggagata aagccatttc attcccctat
     4861 tcaagaatct agccaagata ggtattttgt attctacaaa aaagaaaggc atttccaagg
     4921 gaaacatgtc agataaaaac ttttgtttat tttttactat agatagaacc ttgcttctca
     4981 agagaaagcc attaataata ccgatgacag ctattaatat atagagaata gtataagtat
     5041 gaataatctt cattagacaa aaagaagaaa tggcagataa attacatacg atatattgga
     5101 atataaaata tttacggtct aaaccttgtt cagttgcaat ttttttaaaa ttgccttgca
     5161 taaaaaaatc aaaggcgtcc attaaactat ctttcacatt agaaatttaa aagctaaata
     5221 atacgacaaa caatgtgaag tactattcat ggtttattta aaaaataata ctattctgaa
     5281 cattatttag atacagaaat taacaaatta gaactaaaca agcttttaaa tactttaatt
     5341 ttattggaaa gctataaaag gaactataac tttacacact agtcacttct ttttaagagg
     5401 caaaagggat tgggaaggtc gtcttggaga taagcactgg tatttcggcc aatggtaaat
     5461 agagtttacc tcaaataggg tagaacctcc ttcatctgtc agttaataac agccactttt
     5521 acaatgccct gtcaaaataa agcggcacgc ccgatttttc actcatcgtc atcaaataac
     5581 ccatcacctt ttggggccat tcgatgccgc gcaccacggt cagattcctc aaaacgggga
     5641 aaaccaaaat atcctccata ccgattccgc cgttgatgcc gtctgaagca ccgtccatca
     5701 aattttccaa ctcttgcaaa tctgcgttta tgcgttcgag atattgggcg gttttattca
     5761 aattggcgga aaagctgccg atgcttttct cttttttgtc tgtaaaatat tttaccgctt
     5821 ccggcgttgc aaattcgggc agcccgattt tgatcacgcg cggctgcacc agtttgtcgt
     5881 tgtatccgcc caccttgtcc agccacgccc gtatctcggg gcggacttcg tctttcagac
     5941 ggtcttcgcg gtcgaaatgc cgcacaatgt ccaaactctc gcccataaac gaaccgtctt
     6001 ctttttgcag gacgggcact tgtttcgcac cgatcatacc gatcggcgtt gcctcgtcgt
     6061 cgtttgccag cacggcttct tcaacgtccg cgccaaacag cccggcagcc atccgcgcac
     6121 gcacacaaaa cgggcaatgg tcgtaaatat acagtttcat caaaatattc ctcgtcaacc
     6181 tgtcggtacc ggctacctta acaccccgcg ccacccgaaa caagtttatc ttcccgccta
     6241 tgcaccgtaa ataaataagc tgagaccttt gcaaaaatag tctgttaacg aaatttgacg
     6301 cataaaaatg cgccaaaaaa ttttcaattg cctaaaacct tcctaatatt gagcaaaaag
     6361 taggaaaaat cagaaaagtt ttgcattttg aaaatgagat tgagcataaa attttagtaa
     6421 cctatgttat tgcaaaggtc tcaagctgtt acaataaact cgtttttatc ggaacgaaag
     6481 acccatcatg accgccatca gcccgattca agacacgcaa agcgcgactc tgcaagaatt
     6541 gcgcgaatgg ttcgacagct actgcgccgc gctgccggac aacgataaaa aacttgtctt
     6601 agccgcccgt tcgctggcgg aagcacatta ccccgccgat gccgtcacgc cgtatggcga
     6661 gccgttgtcc gaccacttcc tcggcgcggc acaaatggtc gacgaactcg acctgctgcc
     6721 cgatgccgtc gccgccaccc tgcttgccga catcggacgc tacgtccccg attggaatct
     6781 attggtttcc gaacgctgca acagcaccgt cgccgagctg gtcaaaggtg tggacgaagt
     6841 gcagaaactc acccacttcg cccgggtgga cagcctcgcc acgccggaag aacgcgccca
     6901 gcaagcggaa accatgcgga aaatgctgct ggcgatggtt accgacatcc gcgtcgtgtt
     6961 aatcaaactg gcgatgcgta cgcgcaccct gcaattttta agcaacgccc ccgacagccc
     7021 cgaaaaacgc gccgttgcca aagaaaccct cgacatcttc gccccgctcg ccaaccgttt
     7081 gggcgtgtgg cagctcaaat ggcagctcga agatttgggc ttccgccatc aagaacccga
     7141 aaaataccgc gaaattgccc tgcttttgga cgaaaaacgc accgaacgcc tcgaatacat
     7201 cgaaaacttc ctcaatatcc tgcgtacgga actgaaaaaa tacaatattc attttgaagt
     7261 tgccggaaga ccgaagcaca tctactccat ttacaaaaaa atggtgaaga aaaagctcac
     7321 tttcgacggc ttgttcgaca tccgcgccgt acggattttg gtggacacca ttcccgagtg
     7381 ttataccacg ctgggcattg tccacagcct ctggcagccg attccgggcg agttcgacga
     7441 ctacatcgcc aacccgaaag gcaacggcta taaaagtttg cacaccgtta tcgtcggccc
     7501 ggaagacaaa ggcgtggaag tgcaaatccg caccttcgat atgcaccaat tcaacgaatt
     7561 tggtgttgcc gcccactggc gttataaaga gggcggcaaa ggcgattccg cctacgaaca
     7621 gaaaatcgct tggttgcgcc aactcttgga ctggcgcgaa aacatggcgg aaagcggcaa
     7681 ggaagacctc gccgccgcct tcaaaaccga gcttttcaac gacacgattt atgtcctgac
     7741 cccgcacggc aaagtcctct ccctgcccac gggcgcgacc cccatcgact tcgcctacgc
     7801 cctgcacagc agcatcggcg accgttgccg cggtgcgaaa gtcgaagggc agattgtgcc
     7861 gctgtccacc ccgctcgaaa acggacagcg cgtcgaaatc attaccgcca aagaagggca
     7921 tccttccgtc aactggcttt acgaaggctg ggtcaaatcc aacaaggcaa tcggcaaaat
     7981 ccgcgcctac atccgacagc aaaacgccga caccgtgcgc gaagaaggcc gcgtccaact
     8041 cgacaaacag cttgccaaac tcacgcccaa acccaacctg caagagcttg ccgaaaatct
     8101 cggctacaaa aagccagaag acctctacac cgccgtcgga caaggcgaaa tttccaaccg
     8161 cgccatccaa aaagcctgcg gcacgctgaa cgaaccgccg cccgtacccg tcagcgaaac
     8221 caccatcgtc aaacagtcca aaatcaaaaa aggcggcaaa aacggcgtgc tcatcgacgg
     8281 cgaagacggt ctgatgacca cgcttgccaa atgctgcaaa cccgcgccgc ccgacgacat
     8341 tgtcggcttc gttacccgcg atcgcggcat ttcggtacac cgcaaaacct gcccctcttt
     8401 ccgacacctc gccgaacacg cgcccgaaaa agtactggac gcaagttggg cggcgttgca
     8461 ggaaggacaa gtgttcgccg tcgatatcga aatccgcgcc caagaccgct ccgggctttt
     8521 gcgcgacgta tccgacgcgc tcgcccgcca caaactcaac gttaccgccg tgcaaaccca
     8581 gtcccgcgac ttggaagcca gtatgcggtt cacgctcgaa gtcaaacagg tcaacgacct
     8641 cccgcgcgtc ctcgccagcc tcggcgacgt caaaggcgta ttgagcgtta cccggcttta
     8701 aatacaaaaa tgccgtctga aagccgtata acgcttcaga cggcattttg attgacgggg
     8761 tttgctattt tttgttgcat agtcaattaa aaacaaaata gtacaatact caactttgaa
     8821 ggtctaacca tggcatactc tgcggactta agaaacaaag ctttaaacta tagtggatta
     8881 acaaaaatca ggacaaggcg acgaagccgc agacagtaca aatagtacgg caaggcgagg
     8941 caacaccgta ctggtttaaa tttaatccac
//
LOCUS       DAXISH010000072         8800 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.072, whole genome shotgun sequence.
ACCESSION   DAXISH010000072 DAXISH010000000
VERSION     DAXISH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8800
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.072"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(59..268)
                     /locus_tag="ACFOV4_001819"
                     /pseudo
     CDS             complement(59..268)
                     /locus_tag="ACFOV4_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006249760.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            complement(574..1833)
                     /gene="rho"
                     /locus_tag="ACFOV4_001820"
     CDS             complement(574..1833)
                     /gene="rho"
                     /locus_tag="ACFOV4_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003823056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFC7619774.1"
                     /translation="MHVSELQTLHISKLLELAEEHAIENANRFRKQDLVFAIVRQMMK
                     KGEGFTCSGTLEILPDGFGFLRSADTSYLAGPDDIYVSPTQIRRFNLHTGDTIEGSVR
                     VPKDNERYFALVRLDTINGDHPEVCRHKILFENLTPLFPTEQLKLERDLKSEENLTGR
                     AIDLISPIGKGQRALLVAPPKSGKTVMLQNIAHAVTANYPEVELIVLLIDERPEEVTE
                     MSRSVRGEVVSSTFDEPAQRHVQVAEMVLEKAKRMVEHKKDVVILLDSITRLARAYNT
                     VVPTSGKILTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALVETGSRMDDVIYEE
                     FKGTGNMELHLDRRMAEKRLFPAININKSGTRREELLVPNDQLQRMWLLRKFLHPMDE
                     IEAAEFLIGKIKASKNNDDFFELMRGK"
     gene            complement(2052..4436)
                     /gene="ppsA"
                     /locus_tag="ACFOV4_001821"
     CDS             complement(2052..4436)
                     /gene="ppsA"
                     /locus_tag="ACFOV4_001821"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008986 - pyruvate, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HFC7619775.1"
                     /translation="MADNYVIWFENLRMTDVERVGGKNASLGEMISQLTEKGVRVPGG
                     FATTADAYRAFLAHNGLSERISVALAKLDVEDVAELARVGKEIRQWILDTPFPEQLDA
                     EIEAAWNKMVADAGGADISVAVRSSATAEDLPDASFAGQQETFLNINGLENVKEAMRH
                     VFASLYNDRAISYRVHKGFEHDIVALSAGVQRMVRSDSGASGVMFTLDTESGYDQVVF
                     VTSSYGLGENVVQGAVNPDEFYVFKPTLKAGKPAILRKTMGSKHIKMIFTDKAEAGKS
                     VTNVDVPEEDRNRFSITDEEITELAHYALTIEKHYGRPMDIEWGRDGLDGKLYILQAR
                     PETVKSQEEGSRNLRRFSINGEKTVLCEGRAIGQKVGQGKVRLIKDASEMDSVEAGDV
                     LVTDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATELLKNGQE
                     VTVSCAEGDTGFIYAGLLDVQITDVALDNMPKAPVKVMMNVGNPELAFSFANLPSEGI
                     GLARMEFIINRQIGIHPKALLEFDKQDDELKAEITHRIAGYASPIDFYVDKIAEGVAT
                     LAASVYPRKTIVRMSDFKSNEYANLVGGSIYEPHEENPMLGFRGAARYVAESFKDCFA
                     LECKALKRVRDEMGLTNVEIMIPFVRTLGEAEAVVKALKENGLERGKNGLRLIMMCEL
                     PSNAVLAEQFLQYFDGFSIGSNDMTQLTLGLDRDSGLVSESFDERNPAVKVMLHLAIS
                     ACRKQNKYVGICGQGPSDHPDFAKWLVEEGIESVSLNPDTVIETWLYLANELNK"
     gene            4847..5668
                     /locus_tag="ACFOV4_001822"
     CDS             4847..5668
                     /locus_tag="ACFOV4_001822"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFC7619776.1"
                     /translation="MSSPRHVFYISDRTGLTAENIGEALLNQFGNLSFKRHTHPFVDT
                     PEKARAVVEKVNRSRQENGQRPIAFVSVVDDEIRRIIKGADAFQINFFETFLGLLEKE
                     LNTEATASEQGHHSIGNTKRYDARMEAVNFSLNHDDGVSDKNLQEADVILMGVSRSGK
                     TPTCLYLALQYGIRAANYPLIPDDLESADLPRMVKPYRDKLFGLTIQPERLQAIRQER
                     RPNSTYAKIDTCRSEVADAQSMFRRHGIPFANTTDKSVEELAVHILQACKLKRRF"
     gene            complement(5907..6569)
                     /locus_tag="ACFOV4_001823"
     CDS             complement(5907..6569)
                     /locus_tag="ACFOV4_001823"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFC7619777.1"
                     /translation="MIHAVLFDLDGTLADTALDLGGALNTLLARHGLPAKSMDEIRTQ
                     ASHGAAGLIKLGAGITPDHPDYARWRTEYLDEYDSRYAQDTTLFGGVNELIAELDRRG
                     IKWGIITNKPMRFTDKLAPKLGFIIPPAVVVSGDTCGEPKPSVKPMLYACGQIHADPQ
                     HTLYVGDAERDIQAGRNAGMKTVLAEWGYIAPEDDTGSWQADFHIRTPLDLLECLDKI
                     QP"
     gene            complement(6582..7409)
                     /locus_tag="ACFOV4_001824"
     CDS             complement(6582..7409)
                     /locus_tag="ACFOV4_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFC7619778.1"
                     /translation="MKLDIYALLERALLSGDPDEKGRLTDEAFAAVQNADGAEANAPP
                     ADFPRAGRPDKPVLVAPSQLTPRKMNTTEGYAAMLHAIAHIEFNAVNLALDAAYRFRT
                     LPFQFVRDWVKVAKEEVYHFRLMRDRLRAFGFDYGSFEAHNHLWDMAYKTAYDPLLRM
                     ALVPRVLEARGLDVTPGIRAKVAQRGDSETCGVLDIIYRDEVGHVAIGNRWYQHLCRE
                     RGLEPIALFRSLIARYDMFIFRGYVNIEAREKAGFSRFELDMLEDFEQGLKQNKNTV"
     gene            7839..8462
                     /gene="lolA"
                     /locus_tag="ACFOV4_001825"
     CDS             7839..8462
                     /gene="lolA"
                     /locus_tag="ACFOV4_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HFC7619779.1"
                     /translation="MMKPHNLFQFLAVCSLTVSVASAQAGAVDALKQFNNDADGISGS
                     FTQTVQSKKKTQTAHGTFKILRPGLFKWEYTSPYKQTIVGDGQTVWLYDVDLAQVTKS
                     SQDQAIGGSPAAILSNKTALESSYTLKEDGSSNGIDYVLATPKRNNAGYQYIRIGFKG
                     GNLAAMQLKDSFGNQTSISFGGLNTNPQLSRGAFKFTPPKGVDVLSN"
     gene            8675..>8800
                     /locus_tag="ACFOV4_001826"
     CDS             8675..>8800
                     /locus_tag="ACFOV4_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC7619780.1"
                     /translation="MQAARPSLQCFLFLNERSKTMKKTLVAAAILSLALTACGGGS"
BASE COUNT         1905 a         2212 c         2490 g         2193 t
ORIGIN      
        1 gacgttttgc ccggtttcaa aagttcccaa ttccattgat atggttttgt cgttcagcaa
       61 aataactttc atctgcttct actttgccgt caaacatttc caaatgcgga ctgttttgat
      121 aaataagtaa tcgtaaacga tgaaaataat aggctgcggt atttttatta acgcctacta
      181 actctgctgc tgttcttgca gttacacctg cgacaaatag ctcaatgagt ttattttgtt
      241 tataccggct tagacgactt tttctcataa aggcaactct aacttaattt gaatttccct
      301 agttatctag gacagcccca aatttataca aaaatgagcg cggttcggcg caaccttgaa
      361 tcaagttccc gcatcggttt tcattgccgg tacggatgcg ttcaagccgg ttttgcaaag
      421 gccgcgcttt cggcaagcgg acacggacac tgccgacggt tgcgccgtta acggggggag
      481 ggaggagctg cgccgaccgt gtgaatgaaa gtgccgtctg aaacccgatt ttcaggcttc
      541 agacagcatt tcgcattaat gcgggcggcg cgtttatttg ccgcgcatca gttcaaagaa
      601 atcgtcgttg tttttagagg ctttgatttt cccgattaaa aattcggctg cctcgatttc
      661 gtccatcggg tgcaggaact tgcgtaagag ccacatacgt tgcaactggt cgttcggcac
      721 aagcagctct tcgcggcgcg tgccggattt gttgatgttg atggcgggga agaggcgttt
      781 ttccgccata cggcggtcaa ggtgcaattc catattgccg gtgcctttga attcttcgta
      841 aatcacatcg tccatacggc tgccggtttc aaccaatgcg gtggcgatga tggtcagcga
      901 accgccttct tccacgttgc gcgccgcgcc gaagaaacgt ttggggcggt gcagcgcgtt
      961 ggcatcgaca ccgccggtca ggattttgcc cgaggtgggg acgacggtat tgtaggcgcg
     1021 ggcaaggcgg gtaatcgaat ccagcaggat gaccacgtct tttttgtgtt ctaccatacg
     1081 cttggctttt tcaagcacca tttcggcaac ttggacgtgg cgttgcgccg gttcgtcaaa
     1141 ggtggaggaa accacttcgc cgcggacgga acggctcatt tcggttactt cttcgggacg
     1201 ctcgtcaatc aagaggacga tgagttcgac ttcgggatag tttgcggtaa cggcgtgggc
     1261 aatgttttgc agcatcacgg ttttaccgct tttgggcgga gcaaccaaga gggcgcgctg
     1321 acctttaccg atgggcgaaa tcaggtcgat ggcgcgtccg gtaaggtttt cttcggactt
     1381 taagtcgcgt tccagcttca actgttcggt cggaaacagc ggggtcaggt tttcaaacag
     1441 gattttatgg cggcatactt ccgggtggtc gccgttgatg gtatcaagcc tgaccagggc
     1501 aaaatagcgt tcgttgtctt tggggacgcg gacgctgcct tcgatggtgt cgcccgtatg
     1561 caggttgaag cggcggattt gggtgggtga gacatagatg tcgtcggggc cggcaagata
     1621 ggaggtgtcc gcgctgcgga ggaagccgaa gccgtcgggc aggatttcaa gcgtgccgga
     1681 gcaggtgaaa ccctcgcctt ttttcatcat ctggcggacg atggcaaata cgaggtcttg
     1741 tttgcggaaa cggttggcat tttcgatagc gtgttcttct gccaactcta aaagtttaga
     1801 aatgtgcagg gtttgtaatt cggagacgtg cataataatg atgtattttg aagaggaaaa
     1861 agacaggcag atgccgtctg aaagaagaag ctgaccgttg gcggttgctc ggagaaaggg
     1921 gaattgtagg cagtcggcgc gtgggtgtca aatattatcg cggacggggc atcggcagga
     1981 aatgccgtct gagcggagct gcttggaaaa aatacccccg cgcttttcag gcacgggggt
     2041 atgggcattg attatttgtt taattcattc gccaaataca gccaagtttc gatgacggta
     2101 tccgggttca gagacacgct ttcgatgcct tcctcaacca gccatttggc aaagtccgga
     2161 tggtcggacg ggccttgacc gcagatgccg acatatttgt tctgcttgcg gcaggcggag
     2221 atggcaaggt gcagcatcac tttgacggca gggttgcgtt cgtcaaacga ttcggacacc
     2281 aagccgctgt cgcggtcgag accgagggtc agttgggtca tgtcgttcga gccgatggag
     2341 aagccatcga agtattgcag gaattgttcc gccaataccg cgttgctcgg cagttcgcac
     2401 atcataatca ggcgcaggcc gtttttgccg cgttccaaac cgttttcttt cagggctttg
     2461 acaacggctt cggcttcgcc caaagtgcgg acgaacggaa tcatgatttc aacgttggtc
     2521 aaccccattt catcgcggac gcgtttcaag gctttgcatt cgagggcgaa gcagtctttg
     2581 aaactttcgg cgacataacg cgccgcaccc cggaagccca acatcgggtt ttcttcgtgc
     2641 ggttcgtaga tgctgccacc caccaagtta gcgtactcgt tggatttgaa gtcggacata
     2701 cggacgatgg ttttacgcgg ataaaccgat gcggctaaag ttgccacgcc ttctgcgatt
     2761 ttatcgacat agaagtcaat aggagaggcg tagccggcga tgcggtgggt aatttccgct
     2821 tttaattcgt cgtcttgttt gtcaaattcc aacaaggctt tggggtggat gccgatttgg
     2881 cggttgatga tgaattccat acgcgccaag ccgatgcctt cgctcggcag gttggcgaag
     2941 ctgaatgcga gttcgggatt gccgacgttc atcatcactt tgacaggtgc tttgggcata
     3001 ttgtccaagg cgacatcggt aatctgtacg tccaacaggc cggcatagat gaagccggta
     3061 tcgccttcgg cgcaggatac ggtaacttcc tgaccgtttt tcagcaattc ggttgcattg
     3121 ccgcagccga cgacggcagg aatgcccaat tcacgcgcga taatcgctgc gtggcaggta
     3181 cgtccgccgc gattggtaac gatggcggaa gcgcgtttca tcaccggttc ccaatccgga
     3241 tcggtcatat cggtaaccag tacgtcgccg gcttcgacgg aatccatctc ggaagcatct
     3301 ttaatcaggc gtactttgcc ctgtccgact ttctgaccga tggcgcggcc ttcgcacaag
     3361 acggtttttt cgccgttgat agaaaagcgg cgcaggttgc ggctgccttc ttcttgggat
     3421 ttcacggttt cgggacgggc ttgcaggata tagagtttgc cgtccaagcc gtcgcgaccc
     3481 cattcgatat ccatcgggcg gccgtagtgt ttttcgatgg tcagcgcgta atgcgccaac
     3541 tcggtgattt cttcgtcggt aatggagaag cggttgcggt cttcttcggg gacatcgacg
     3601 ttggttaccg atttgccggc ttcggctttg tcggtaaaaa tcattttgat gtgtttcgaa
     3661 cccatggttt tacgcaggat ggcgggcttg cccgctttga gcgtaggttt gaacacataa
     3721 aattcgtccg ggttgaccgc gccttgtacg acgttttcgc ccagaccgta agaggaggta
     3781 acaaagacga cttgatcgta gccggattcg gtgtcgaggg tgaacatcac acctgatgcg
     3841 ccactgtcgg aacgcaccat gcgttgaacg ccggcggaaa gggcgacgat gtcgtgttcg
     3901 aagcctttgt ggacgcggta ggaaatggcg cggtcgttgt acagggaggc gaatacatgg
     3961 cgcatcgctt ctttaacgtt ttccaagccg ttgatgttca agaaggtttc ctgttgtccg
     4021 gcaaatgatg cgtccggcag gtcttcggcg gttgcggaag agcgtacggc aacggaaatg
     4081 tccgcaccgc cggcatcggc aaccattttg ttccatgccg cttcgatttc ggcatcgagc
     4141 tgttcgggga agggcgtgtc caaaatccat tggcggattt ctttgccgac gcgtgccagt
     4201 tcggcaacgt cttcgacatc caattttgcc agtgcgacgg aaatgcgttc gctcagaccg
     4261 ttgtgtgcga ggaatgcgcg gtaggcatcg gccgtggtgg caaagccgcc ggggacgcga
     4321 acgccttttt cggtcagctg actaatcatt tcacccagcg aggcgttttt accgcccacg
     4381 cgttcaacat ctgtcatacg caggttttca aaccagatta cgtagttgtc ggccatttgt
     4441 gtgtccaatc caaaatatgt taaaaaagaa acaaatccgc gtgcttattt taagcgattc
     4501 gttcctctgc tgtcatgtgt tttatccgtt ttaaaatcat gatgccgtct gaaaaattgc
     4561 ggtttcggcg tgtgtagcgg tttgaaactt gcagccggta tacttctttt tttgggtatt
     4621 ttctttgtaa aacaggtggt ttgaataggt taatgttttt tctgtttgat ttttttgttt
     4681 attttttaaa attttctgcc aaaaaatact ttatataaat aattttattt caaaattata
     4741 ttgtgtctgt ttgggtgtaa tccgaggtag gcgtgctgcg ggtgctttcc ttgtgtctgc
     4801 cgctgctgtt atgatgatat ttttattctg tatttaagga tggaagatga gcagtccgcg
     4861 ccatgtgttt tacatttccg accgtaccgg tctgactgcc gagaatatcg gcgaggcttt
     4921 gctgaaccag tttggcaatc tgtcgttcaa acgccatacg catccgtttg tcgatacgcc
     4981 ggaaaaggcg cgcgcggtgg tggagaaggt caatcggagc cggcaggaaa acggtcagcg
     5041 tccgattgcg tttgtcagtg tggttgatga cgaaatccgt cggattatca aaggggcgga
     5101 tgcttttcag attaatttct ttgagacttt tttgggactg ttggagaaag aactcaatac
     5161 cgaagccacg gcatccgagc aggggcatca cagtatcggt aatacgaagc gttacgatgc
     5221 gcgtatggag gcggtgaatt tctcattgaa ccacgatgac ggggtcagcg ataagaacct
     5281 tcaggaagcg gatgtaatct tgatgggtgt atcgcgttcg ggcaaaacgc cgacctgcct
     5341 ttacctcgcc ctgcaatacg gcatccgtgc ggcaaactat ccgctgattc ccgacgattt
     5401 ggaatcggcc gatctgccgc gtatggtcaa gccttatagg gataagctgt tcgggttgac
     5461 catccagccg gaacgtttgc aggccatccg ccaagagcgc cgcccgaatt caacttatgc
     5521 caaaatcgat acatgccgca gcgaggtggc ggacgcgcag agtatgttca gacggcatgg
     5581 cattccgttt gcgaatacga cggataaatc ggttgaggaa ttggcggtac acatccttca
     5641 ggcgtgcaag ctcaaacgca ggttttgacg ggctttgatt cggtttgaag gcggaactgc
     5701 cgtctgaaat caggtttcag acggcagttt tatagtggat taacaaaaat caggacaagg
     5761 cgacgaagcc gcagacagta caaatagtac ggaaccgatt cacttggtgc ttcagcacct
     5821 tagagaatcg ttctctttga gctaaggcga ggcaacgctg tactggtttt tgttaatcca
     5881 ctatatgttt gtggggcgga tatttttcag ggctgtattt tgtccagaca ttcgagcaga
     5941 tcgagtggcg tgcggatgtg gaaatccgcc tgccatgagc cggtatcgtc ttcgggagcg
     6001 atgtagcccc attcggcgag gacggttttc atgccggcgt tgcggcctgc ttggatgtcg
     6061 cgttcggcat caccgacgta gagtgtgtgt tgcgggtcgg cgtggatttg tccgcacgca
     6121 tacagcatgg gtttgacgct gggcttgggt tcgccgcagg tgtcgccgct gacgacgacg
     6181 gcgggtggga tgatgaagcc gagtttgggg gcgagtttgt cggtgaagcg catgggtttg
     6241 ttggtgatga tgccccattt gatgccgcgt ctgtcgagtt cggcgatgag ttcgttcacg
     6301 ccgccgaaga gggtggtgtc ttgggcgtag cggctgtcgt attcgtcaag gtattcggtg
     6361 cgccatcggg catagtcggg gtggtcgggg gtgatgcctg cgccgagttt gatcagtcct
     6421 gccgcgccgt ggctggcttg ggtgcggatc tcgtccatgc tttttgcagg tagtccgtgg
     6481 cgagcgagca gggtgttgag tgcgcctccg aggtcgaggg cggtgtcggc aagtgtgccg
     6541 tcgaggtcga agagtacggc gtgtatcatg tgtgttcctt ttcagacggt atttttgttc
     6601 tgtttcaaac cctgctcgaa atcttccagc atatccaatt caaagcggct gaagccggct
     6661 ttttcgcgcg cttcgatgtt cacatagcca cggaagataa acatatcgta acgggcaatc
     6721 agactgcgga acagggcaat cggttccaaa ccgcgttcgc ggcagaggtg ttgataccac
     6781 cggttgccga tggcgacatg gcccacttcg tcgcggtaaa tgatgtccaa tacgccgcag
     6841 gtttccgaat cgccgcgctg cgccaccttc gcgcgtatcc ccggcgtaac gtccagcccg
     6901 cgcgcttcca acacgcgcgg taccaacgcc atacgcaaca gcgggtcgta ggcggttttg
     6961 tacgccatat cccacaaatg gttgtgcgcc tcgaaactgc cgtaatcgaa gccgaaagcg
     7021 cgcaatctgt cgcgcatcag gcggaaatgg tacacctctt ccttcgccac tttcacccag
     7081 tcgcggacaa actgaaacgg cagcgtgcgg aaacggtatg ccgcgtccaa agctagattg
     7141 acggcgttga attcgatatg cgcaatcgcg tgcagcatcg ccgcataacc ttcggttgtg
     7201 ttcattttgc gcggggtcag ttgcgacggc gcgaccaaaa caggcttgtc cggccgtccc
     7261 gctcggggga agtccgccgg cggcgcgttt gcttccgccc cgtccgcatt ttgaacggcg
     7321 gcaaacgcct catccgtcag ccgtcctttt tcatctgggt cgcccgaaag cagggcgcgt
     7381 tccagcaaag cataaatatc gagtttcatc tcaagtccgc cgtgttcgga aaacaaatat
     7441 tatagcgttt taaaaaaaca agatgaggca tataatctcc gcgattcggc attccgcgcc
     7501 caaaccgtca aatatagtgg attaacaaaa accggtacgg cgttgcctcg ccttagctca
     7561 aagagaacga ttctctaagg tgctgaagca ccaagtgaat cggttccgta ctatttgtac
     7621 tgtctgcggc ttcgtcgcct tgtcctgatt tttgttaatc cactataacg cggcacacat
     7681 taaagggcag cgtggcgcgc ctgccttttc cgagcggtca aaaaaatcag ccctcggaaa
     7741 acgctgtttg taaaatgcaa accgcccgta acgccgcccg tatgattgtt ttgccgcgcc
     7801 gatactttac gccacaccca tcccaacaag gaaaaataat gatgaaaccg cacaacctgt
     7861 tccaatttct cgccgtttgc tccctgaccg tctccgtcgc ttccgcacag gcgggcgcgg
     7921 tggacgcgct caagcaattc aacaacgatg ccgacggtat cagcggcagc ttcacccaaa
     7981 ccgtccaaag caaaaagaaa acccaaaccg cgcacggcac gttcaaaatc ctgcgcccgg
     8041 gcctcttcaa atgggaatac acttcgccct acaaacagac tattgtcggc gacggtcaaa
     8101 ccgtttggct ctacgatgtt gatttggcac aagtgaccaa gtcgtcccaa gaccaggcca
     8161 taggcggcag ccccgccgcc atcctgtcga acaaaaccgc cctcgaaagc agctacacgc
     8221 tgaaagagga cggttcgtcc aacggcatcg attatgtgct ggcaacgccc aaacgcaaca
     8281 atgccggcta ccaatacatc cgcatcggct tcaaaggcgg caacctcgcc gccatgcagc
     8341 tgaaagacag cttcggcaac caaacctcca tcagtttcgg cggtttgaat accaatcccc
     8401 aactctcgcg cggcgcgttc aagtttaccc cgcccaaagg cgtggacgtg ttgagcaact
     8461 gatgccgtcc gccccgatgc cgtctgaaag ccgccgaggc ttcagacggc attttcacgc
     8521 aggcggaaca atgtcccgca ttaccgcccg atcgggcatc ggaacggcaa acccgtgaaa
     8581 attaacggtt gcgccccggt tgtttttgcc gtttaatgca aaccttgctg caccaagggc
     8641 caagaaagcc gaccggccgc ccccacagct tccgatgcag gcggcccggc cgtccctgca
     8701 atgtttttta tttttgaacg aaaggtcgaa aaccatgaaa aaaacactgg tggcggcggc
     8761 aatcctgagc ctcgccttga ctgcgtgcgg cggcggaagc
//
LOCUS       DAXISH010000073         8797 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.073, whole genome shotgun sequence.
ACCESSION   DAXISH010000073 DAXISH010000000
VERSION     DAXISH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8797
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.073"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(94..774)
                     /gene="tsaA"
                     /locus_tag="ACFOV4_001827"
     CDS             complement(94..774)
                     /gene="tsaA"
                     /locus_tag="ACFOV4_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HFC7619781.1"
                     /translation="MTYTITPIGTARSPYKQKFGIARQPGLVSAAEVCIELNPKFTAD
                     SVRGLEDFDYVWISFIFHGVLDEGWAQMVRPPRLGGKQKMGVFATRSPHRPNHLGLSL
                     LKLERIETGKPVRLYCSGADLLDGTPIVDIKPYIPFVESKPDAASGFVSGKPVELEVV
                     WQENIGAENLSANTKNLISQSIAQDPRPAYQNIPERIYVMNIADYEVRFQIEENRATV
                     IDLSPTPL"
     gene            888..1523
                     /locus_tag="ACFOV4_001828"
     CDS             888..1523
                     /locus_tag="ACFOV4_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamidase"
                     /protein_id="HFC7619782.1"
                     /translation="MIVSIDVDAQKTFTPLCPDELPVNEGHLIVEELNAQAALADLRV
                     MTKDAHHMVAKWLVDNPVDMLKPTGLPDADLTWVAHAMVGTRGYELLDGLPSTKEYDY
                     CVWKGVDPELHPYGACFHDIEEKLSTGLIEWLRCQNTDTVIIGGLATDYCVKTTVLQL
                     LKGGRWQVVVNEAACRGIAPETIETAWQEMHSAGAIILKNADEINKYINNQ"
     gene            1560..2528
                     /gene="waaC"
                     /locus_tag="ACFOV4_001829"
     CDS             1560..2528
                     /gene="waaC"
                     /locus_tag="ACFOV4_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008920 - lipopolysaccharide
                     heptosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase I"
                     /protein_id="HFC7619783.1"
                     /translation="MKILLVRLSSMGDLIHTLPAIEDLARQCPDVELHWLCEAGFADI
                     ARLHPFVKKIHVMKWRQWRKHLFRAETWREMGHLKQTLRQEVFDFVLDSQGLIKSACF
                     AKMAKSPICGLDKNSAREGWAALAYVETYAVPKGKNAVWRNRELFAQVFGYVMPETQV
                     FGLTAPEAGRLKNLEQPYYAALHATSRDSKLWPVENWRALLQKLNEEQQCNIYLPWGS
                     EVEKTRAEQIADGLPFAIVCDKINLLQAAYLLKYAVGIVGVDTGLLHLANALEKPVVG
                     IYTDTDPIKTGVQVSPIAKNLGNIGQIPTADLVYQTLMDCVAADKG"
     gene            2754..3503
                     /locus_tag="ACFOV4_001830"
     CDS             2754..3503
                     /locus_tag="ACFOV4_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HFC7619784.1"
                     /translation="MKALVAVKRVVDYNVKVRVKADGSDVDIGNVKMSMNPFDEIAVE
                     EAVRLKEAGKVSEIVAVSLGEKKCEETLRTALAMGADRAIHVETDTKLESLAVAKLLK
                     AVADKENPQIFFLGKQAIDDDANQVAQMLAALLNAAQGTFASKVHIEGGEVQIVREID
                     GGEETIALKLPAVISADLRLNEPRFVKLPNIMAAKKKTLEKLTPDDLVADISPRLKTV
                     KFAEPKARQAGVKVASVAELVEKLKNEAKVI"
     gene            3514..4449
                     /locus_tag="ACFOV4_001831"
     CDS             3514..4449
                     /locus_tag="ACFOV4_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFC7619785.1"
                     /translation="MSVLIIVEHDNKQLNPTTLHAVTAAAKLGKIDLLVAGSGASAVV
                     EFAKQVAGVEKVLVADAAHYAEGLAEELAPLVVKLAADYCYVAATATTFGKNLLPRVA
                     ALLDVPQISDLTEIVDNTTFVRPIYAGNAFETVQADSEKLVLTFRATVFDAVAAQGGN
                     AEVINVEATPAQNLSRFVNRQLSHSDRPELTQAKVIVSGGRALGSAEKFNEVLTPLAD
                     VLGAAIGASRAAVDAEYAPNDAQVGQTGKVVAPQLYFAIGISGAIQHVAGMQDSKVIV
                     AINKDADAPIFNVADYGLVGDLFEIVPQLTEALKN"
     gene            4512..5123
                     /locus_tag="ACFOV4_001832"
     CDS             4512..5123
                     /locus_tag="ACFOV4_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFC7619786.1"
                     /translation="MITTYKTITSSTQAEFKDKGSRFIAFAYPIRTLADVKKYLDPLK
                     EEHHKARHWCYAYRLGVDGMQFRANDDGEPSGSAGRPILGQIDSVGITDVLVVVVRYF
                     GGTLLGVPGLIHAYKEATAQALAVAEVVEKNIEKTVWLKCEYPFLNEAIRIAKQYQAD
                     VLERDLQLDCRLTVSLSLVNYEACVAAWKSTRQIEVNTEKPFE"
     gene            complement(5175..5492)
                     /locus_tag="ACFOV4_001833"
     CDS             complement(5175..5492)
                     /locus_tag="ACFOV4_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HFC7619787.1"
                     /translation="MQKRIDEIQSKYREWCHLLPQLEEDIRRWKHAVALIRDMDNFYT
                     HEYQACHRAIEDGAEVDLRTEGEYSIMSEDALWNALGEFHQLAWLYLRSSVDALDKYT
                     QED"
     gene            5650..6921
                     /gene="purD"
                     /locus_tag="ACFOV4_001834"
     CDS             5650..6921
                     /gene="purD"
                     /locus_tag="ACFOV4_001834"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFC7619788.1"
                     /translation="MKLLVIGNGGREHALAWKLAQSPKVETVFVASGNAGTAIEPKLQ
                     NIDLTAHQDLIEFCRKENIVFTVVGPEAPLAAGVVDDFRAAGLKIFGPTQYAAQLESS
                     KDFAKAFMAKYNIPTAQYQTFENADAAHDYVNQKGAPIVIKADGLAAGKGVIVAMTLD
                     EAHAAIDDMLLDNKMGNAGARIVIEDFLQGEEASFIVMVDGNNVLPMATSQDHKRLLD
                     GDKGLNTGGMGAYSPAPVVTPVVYERAMNEIILPTVAGMKAEGHEFTGFLYAGLMIDQ
                     SGAPHTIEFNCRFGDPETQPIMSRLNSDLSDLVEAAIDGKLDSVTAEWSPQTAVGVVL
                     AAQNYPETPKKGDVISGLDAANQVGKVFHAGTTANEKGDVLTNGGRVLCVVGLGDNVA
                     QAKAKAYGALEKISFDGMQYRKDIADKAINR"
     gene            6955..7557
                     /locus_tag="ACFOV4_001835"
     CDS             6955..7557
                     /locus_tag="ACFOV4_001835"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFC7619789.1"
                     /translation="MTNVLQTVFYIMLFPRIIAASAQRKLSVYLKKGGLVAYPTESCY
                     GLGCLPTLAKALGKLAHLKKRPQHKGMIVIGNQFEQLQPLLQMPSENLQDMLRKEWPA
                     PKTFLLSAKSCVLPELRGKQRSKLAVRVPAHVGARRLCQALQTPLVSTSCNRAGKRAC
                     RTEREVRRQFGRDVWIVGGRIGRQKSPSQIIDGETGKRLR"
     gene            complement(7628..8281)
                     /locus_tag="ACFOV4_001836"
     CDS             complement(7628..8281)
                     /locus_tag="ACFOV4_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC7619790.1"
                     /translation="MKITHCKLKKKVQKELLRFFVLEVTARSAADILGIHPNSAALFY
                     RKIRTVINHHLALAADEVFEDPVEPDESDFGGWRKGRCGRGAAGKVVVFDILKRNGRV
                     YTVVVNNAKSETLLPVIKKKIMPDSIVYTDSLSSCDKLDVSGFIYYRINHSKEFADRQ
                     NHINGIENFWNQAKRVLRKYNGIDRKSFPLFLKECEFRFNFGTPSRQLKILQDWCGI"
     gene            8296..8652
                     /locus_tag="ACFOV4_001837"
                     /pseudo
     CDS             8296..8652
                     /locus_tag="ACFOV4_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2326 a         1745 c         2307 g         2419 t
ORIGIN      
        1 ttaatccgct ataacttgat attgcggctt atggcgaaca aacaacagcc gtttgttcaa
       61 ctgctatgcg gcaaaaccgg atttttgccc gatttaaagc ggggttgggg aaagatcaat
      121 aacggttgca cggttttcct cgatttgaaa tctgacttcg taatctgcaa tattcatcac
      181 ataaatccgt tcgggaatat tctgataggc ggggcgcgga tcttgggcaa tgctttggct
      241 gataaggttt ttggtgtttg cagataaatt ttccgcgccg atgttttcct gccaaacgac
      301 ttccaactct acgggtttgc cgctgacgaa accggatgcg gcatcgggtt tggattcgac
      361 aaaggggata taaggtttga tgtccacaat cggtgtgccg tccagcaggt ctgcgccgct
      421 gcaatagagg cggacgggtt tgccggtttc gatgcgttcg agtttcagga gcgagagtcc
      481 gagatggttg gggcggtggg ggctgcgcgt ggcgaacacg cccatttttt gtttgccgcc
      541 gagccgtggc gggcgcacca tttgcgccca gccttcatcc aatacgccgt gaaaaataaa
      601 acttatccac acataatcga aatcttccag cccgcgcacg ctgtctgcgg tgaatttggg
      661 attcagctcg atgcatactt ctgcggcaga gaccaaaccg ggctggcggg cgatgccgaa
      721 tttctgtttg tagggcgagc gggcggtgcc gatgggggta atggtataag tcataaggtt
      781 gtggataagt tttttggaaa aaccttatct tatcacaatc ggttttaccg cttttgggca
      841 gtaatttgtt ataatacagg gcattttaat cgcgttgaaa taatgagatg attgtttcca
      901 ttgatgttga tgcacaaaaa acgtttacgc cactgtgtcc tgacgaactg cccgtgaacg
      961 aagggcattt gattgtcgag gagttgaatg cgcaagccgc tttggcggat ttgcgcgtga
     1021 tgacgaaaga tgcgcatcat atggtagcga aatggcttgt ggataaccct gttgatatgt
     1081 tgaagccgac aggtttgcct gatgcggatt tgacttgggt ggctcatgcg atggtcggta
     1141 cgcgcggcta tgaattattg gacggactgc cttctaccaa agaatacgat tattgcgttt
     1201 ggaaaggtgt tgatcctgaa ttgcatcctt acggcgcgtg ttttcacgat attgaggaaa
     1261 aactaagcac agggctgatt gaatggctgc gttgtcaaaa tacggatacg gttattatcg
     1321 gtgggttagc tacggattat tgtgttaaaa caacggtttt gcagttactc aaaggcggtc
     1381 gttggcaggt tgtcgtcaat gaagcggctt gtcggggtat tgcgccggaa accatcgaaa
     1441 cagcatggca ggaaatgcat tctgctgggg caatcatctt aaaaaacgct gatgaaataa
     1501 ataaatatat taataatcaa taagttaaaa ttgtttcacg tgaaaccccc ttcctaaata
     1561 tgaaaatttt gcttgtccgc ttgtctagta tgggcgattt aattcacact ttgcccgcaa
     1621 tcgaagattt ggcgcgacaa tgtcctgatg tagaactgca ttggctatgt gaggctggat
     1681 ttgcagatat tgcgcgcctg catccgtttg taaaaaaaat ccatgtgatg aaatggcggc
     1741 aatggcgcaa acatctcttt cgggctgaaa cttggcggga aatgggtcat ctgaaacaga
     1801 ctttgcggca ggaagtattt gatttcgtat tggacagtca aggtctgatt aaaagcgcgt
     1861 gtttcgccaa aatggcaaaa tccccgattt gtggtttgga taaaaacagt gcgcgcgagg
     1921 gatgggctgc tttggcgtat gtagaaacat acgctgtacc gaagggaaaa aatgccgttt
     1981 ggcgcaaccg tgaactgttt gcccaagtat ttgggtatgt aatgcctgaa acgcaggtat
     2041 ttggcttgac tgctcctgag gcaggtcgtc tgaaaaattt agagcagccg tattatgcgg
     2101 ctttgcacgc gactagccga gacagtaaat tatggcctgt ggaaaactgg cgggcgttac
     2161 tgcaaaagtt gaatgaagaa cagcaatgca atatttacct gccttgggga agtgaagttg
     2221 aaaaaacgcg tgccgaacag attgcagacg gactgccgtt tgctattgtg tgcgacaaaa
     2281 taaatttatt gcaggcagcg tatctgctga aatacgcggt cggaattgtc ggcgtggata
     2341 ccggtttgct gcatttggca aatgccttgg aaaaacctgt ggtcggcatt tataccgata
     2401 ccgatccgat taaaacaggc gttcaggttt cgccaattgc aaaaaatttg ggcaatatcg
     2461 ggcagattcc gaccgcagat ttggtttatc aaacgttgat ggattgtgtt gcagcagaca
     2521 aaggctaaag ggttgtctga aactgatata gcacctgata tttttcagtt tgttaagcat
     2581 aagaatgtat atctaccagc ctgagtaaat gctttaaaaa tggtataatc ggcaagcatt
     2641 atccgaaaga tttttgaatg aattcgtttt taaggaaaac ggatttggtt ttatagggaa
     2701 gaaggtttgg tttcgctgga tggtgaaagc agcgttcttt ttaggagggt tcaatgaaag
     2761 cactggtcgc agtaaagcgc gtagtggact acaacgtcaa agttcgtgta aaagccgatg
     2821 gttcggatgt ggatatcggc aatgtcaaaa tgtcgatgaa tccgtttgac gaaatcgctg
     2881 tggaagaagc tgtccgtttg aaagaagccg gaaaagtaag cgaaatcgta gcggtttctt
     2941 tgggtgagaa aaaatgcgaa gaaaccttgc gtacagcttt ggcgatgggt gccgaccgtg
     3001 ccattcatgt tgaaaccgat actaaactgg agtctctggc cgttgctaag ttgctgaaag
     3061 ccgttgcgga caaagaaaat ccgcaaattt tctttttggg caaacaagcg attgatgatg
     3121 atgccaatca agtggcgcaa atgctggcag ctttgctgaa tgcggcgcaa ggtacgtttg
     3181 cttcaaaagt acacattgaa ggtggtgaag tacagattgt gcgcgaaatt gatggcggcg
     3241 aagaaaccat agcattaaaa ctgcctgctg ttatcagtgc tgatttgcgt ttgaacgagc
     3301 cgcgctttgt caaactcccc aatattatgg cggcaaagaa aaaaactttg gaaaaactga
     3361 ctcctgacga tttggttgcc gacatttcac ctcgtttgaa aacggtgaaa tttgccgaac
     3421 ctaaggcgcg tcaggcaggc gtaaaagtag caagcgttgc cgaattggtt gaaaaattga
     3481 aaaacgaagc caaagtgatt tgaggaggct gaaatgagcg tattgattat tgtcgaacac
     3541 gacaacaaac agttgaatcc taccactttg catgctgtta ccgctgccgc taagctgggt
     3601 aaaatcgatt tattggttgc cggaagcggt gcatctgctg tagtagagtt cgcaaaacaa
     3661 gtggcgggtg tggaaaaagt tttggttgca gatgctgccc attatgccga aggtttggct
     3721 gaagagttgg ctccgctggt tgtcaaattg gcagcggatt actgctatgt tgcagcaacg
     3781 gcaactacat tcggtaaaaa ccttttgcct cgcgtagcag ccttattaga cgtaccgcaa
     3841 atttctgatt tgaccgaaat tgtggataac acgacttttg tgcgccccat ttatgcgggt
     3901 aatgcatttg aaaccgtgca agctgattca gaaaaattgg tgctgacctt ccgtgcgacg
     3961 gtttttgacg cagtggcggc gcaaggtggt aatgctgagg taattaatgt tgaagcaacc
     4021 cctgcccaaa acctgagccg ttttgttaac cgtcagcttt cccattccga tcgtcctgaa
     4081 ctgactcagg caaaagtgat tgtttccggt ggtcgtgcgt tgggtagtgc ggaaaaattc
     4141 aatgaagtgc tgacaccgtt ggcggatgtt ttaggtgcgg caatcggtgc atcccgtgcg
     4201 gcggttgatg ccgaatatgc gccaaacgat gctcaagtcg gacaaaccgg taaagtggtt
     4261 gcgccgcaac tctattttgc aatcggtatt tcaggtgcga ttcaacacgt tgccggtatg
     4321 caagacagta aggtgattgt tgcaatcaat aaagatgctg atgcgccgat tttcaatgta
     4381 gccgattacg gattggttgg cgatttattt gaaatcgttc cacaattaac agaagcattg
     4441 aaaaattaat gtttcacgtg aaacgttcag acgaccttgt tattaatgag gtcgtctgaa
     4501 aacatttcag catgattacg acttataaaa ccattacttc ctcgacgcag gctgagttta
     4561 aagataaagg cagccgtttt attgcatttg cctatccgat tcggacattg gctgatgtga
     4621 aaaaatacct cgatccgtta aaggaagagc atcataaagc acgacactgg tgctatgcct
     4681 atcgtttggg tgtggatggc atgcaatttc gtgccaacga tgatggagag ccatcaggaa
     4741 gtgctggacg accaattttg ggacagattg attcggtggg tattaccgac gttttggtcg
     4801 tggtcgtccg ctatttcggt ggtactttgt taggtgttcc aggtctgata catgcgtaca
     4861 aagaggcgac ggctcaagcg ttggcagttg cagaagtagt tgaaaagaat attgaaaaaa
     4921 ctgtttggct gaaatgtgaa tatccgtttt tgaatgaagc gatacgcatt gctaaacaat
     4981 atcaggcgga tgtattggag cgggatttgc agttggattg ccgattgacg gtcagtttgt
     5041 cgttggtaaa ttatgaggcc tgtgttgcgg cttggaagag tacacggcag attgaagtaa
     5101 atacggaaaa gccttttgaa tgaaaggtcg tctgaaatgc tttgtgatgg tatttcagac
     5161 gacctcttcg ctgactaatc ttcttgtgta tatttgtcta aggcatcgac gctggagcgc
     5221 aaatataacc aagccagttg atggaattcg cccagcgcgt tccatagtgc atcttcactc
     5281 ataatgctgt attcgccttc tgtgcgcaaa tccacctccg ctccatcttc aatagcccga
     5341 tgacaagcct gatattcgtg ggtataaaaa ttgtccatat cgcgaatcaa agcgacggca
     5401 tgtttccaac ggcggatgtc ttcttccaat tgcggtagta aatgacacca ttcgcggtat
     5461 ttgctttgga tttcatcaat acgtttttgc atggttgctt gtcctttttt aatttatgaa
     5521 taagttgaat aggttgcaga gtggaatgaa gcggtctttt gtttgattct actaaaattt
     5581 cttcagatgg gataaaagtc cctttgtatc gagttttcgt taaaagtaca tatttgtcaa
     5641 ggagatggca tgaaactgct ggttatcggt aatggcggtc gcgaacacgc gctggcttgg
     5701 aaattggcgc agtcgcctaa agtggaaaca gtatttgttg cgtctggtaa tgccggtaca
     5761 gcgattgaac ccaagctgca aaacatcgac ttgactgcgc atcaggattt gattgaattc
     5821 tgtcgtaaag aaaatattgt ttttaccgtc gtcggccctg aagcgccttt ggcggcaggt
     5881 gttgtggatg atttccgtgc tgcaggacta aaaatattcg gtccgacaca atatgcggcg
     5941 cagttggaaa gttccaaaga tttcgccaaa gcatttatgg cgaaatacaa tattccgacc
     6001 gcgcaatatc aaacctttga aaacgccgat gccgcacatg attacgtcaa tcagaaaggt
     6061 gcgcctatcg ttatcaaagc cgatggtttg gcggcaggta aaggcgtgat tgtggcgatg
     6121 actttggatg aagcgcatgc tgcgattgat gatatgctgc tggacaacaa aatgggcaat
     6181 gccggcgcgc gtattgtgat tgaagatttc ctgcaaggcg aagaagcgag ttttatcgtc
     6241 atggttgatg gcaataatgt actgcctatg gcaaccagcc aagaccacaa gcgtctttta
     6301 gacggcgaca aaggtctgaa tacgggcggt atgggtgcgt acagccctgc gcctgtggta
     6361 acgcctgttg tgtacgaacg cgcgatgaat gaaattattt tgccgaccgt agcagggatg
     6421 aaagcggagg ggcatgagtt caccggtttc ctgtacgcag gtttgatgat tgatcaaagc
     6481 ggtgcacccc atacgattga gtttaactgc cgtttcggcg atcctgaaac ccagccgatt
     6541 atgagccgac tgaacagcga cttatcggat ttggttgaag cggcaataga cggcaaactc
     6601 gatagcgtaa ccgcggaatg gagcccgcaa actgccgtgg gcgtggtact ggcggcgcaa
     6661 aattaccccg aaacgcccaa aaaaggcgat gttatttccg gtctggatgc tgccaaccaa
     6721 gtaggcaaag ttttccatgc aggtacaacg gcaaacgaga aaggtgacgt attgaccaac
     6781 ggcggacgcg tattgtgtgt tgtgggattg ggcgataatg tggcgcaagc gaaagctaag
     6841 gcatatggcg cgttggaaaa aatcagtttc gacgggatgc aataccgtaa agacattgcc
     6901 gataaagcga ttaaccgtta attagaaaga ggatgatgcc gtctgaagcc aagtatgact
     6961 aatgtgcttc agacggtatt ttatattatg ttatttccga gaattatcgc agcatcagcg
     7021 caacgtaagt taagcgttta tttgaaaaaa ggtggtttgg tcgcttatcc gaccgaatct
     7081 tgttatggct tggggtgtct tccgacatta gccaaagcac tcggtaagtt ggcgcatttg
     7141 aaaaaaagac cgcaacacaa gggtatgatt gtcatcggga atcaatttga acaattgcag
     7201 cctttacttc aaatgccgtc tgaaaatctt caggatatgc ttagaaaaga atggcccgcc
     7261 cctaaaacgt tcctattatc cgccaaatcc tgtgtcttac ccgagttacg cgggaaacag
     7321 cgcagcaagt tggcggtcag ggttcccgcc catgtaggtg cgcgccgctt gtgtcaggct
     7381 ttgcaaacgc ctttggtctc gacttcgtgc aaccgcgcag gcaaacgcgc gtgtcggacg
     7441 gagagggaag tcagaaggca attcggacgc gatgtgtgga ttgttggtgg gagaatcggc
     7501 aggcagaaat cgccgagtca gattattgac ggggaaacag gtaaacgttt gcgttagata
     7561 tgggtacttg aatgaaaact tttttgcata cacaaagaaa aaattttggg gctgtactag
     7621 attagcccta aatcccacac caatcctgta ggatttttag ctgccgggac ggtgtgccga
     7681 agttaaatcg aaattcgcat tctttcaaga acagcgggaa agatttgcga tcgattccat
     7741 tgtattttcg caagacacgt tttgcctgat tccaaaaatt ctcaatgccg ttaatgtggt
     7801 tctgacggtc tgcaaattcc ttggaatggt tgatgcggta ataaatgaaa ccgctcacgt
     7861 ccaacttgtc gcagctgctc agactatcgg tataaacaat actgtccggc atgattttct
     7921 ttttgatgac agggagtaac gtttcagact tggcattgtt tacgacaacg gtatagaccc
     7981 gtccgttgcg tttcagaatg tcgaagacaa ccacttttcc tgccgcacca cgaccacatc
     8041 tgcctttacg ccacccgccg aaatcgcttt cgtccggctc gacaggatcc tcaaaaacct
     8101 catcggcagc cagggccaaa tgatggttga taaccgtgcg gattttacgg tagaacagtg
     8161 ctgccgaatt gggatggata cccaaaatat cggcggcaga acgggcggta acttccagca
     8221 caaaaaaacg gagcagttct ttctgtactt ttttctttaa tttgcagtgc gttatcttca
     8281 tatttcgagg gtaacatatc tgctaatcta gtacagcccc taaatttttc ggatggtatt
     8341 tctctgcatg attgttattg cacagagata aaggtagaag gacgcaacgt ctactttgat
     8401 tttgaggacg gttttgtcgt tccggacaat aatccgaaca atcaagcggg caagcatctg
     8461 aaaacagatt tttcccgtgt tgttttaacc cataaaaatg aaaacggcga agatgattat
     8521 ttggtcgata tttttgaaga catcgttttt ttagggaaac gtttgtttac ggtcagaaaa
     8581 tttcttgatt tttctgaatt gcttgagatg gttaatacac aaggttattt tcttgagttt
     8641 ctgtatttgt atagtggatt aaatttaaac cagtacagcg ttgcctcgcc ttgccgtact
     8701 atctgtactg tctgcggctt cgtcgccttg tcctgatttt tgttaatcca ctatatgagt
     8761 gtatcggtgt caaaacaagc gattattttt tagaggc
//
LOCUS       DAXISH010000074         8783 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.074, whole genome shotgun sequence.
ACCESSION   DAXISH010000074 DAXISH010000000
VERSION     DAXISH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8783
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.074"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(120..1337)
                     /locus_tag="ACFOV4_001838"
     CDS             complement(120..1337)
                     /locus_tag="ACFOV4_001838"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFC7619791.1"
                     /translation="MALIVHKYGGTSVGSPERIKNVAKRVAKARAEGHDIVVVVSAMS
                     GETNRLVALAHEMQEHPDPRELDVVLSTGEQVTIGLLAMALKDIGVDAKSYTGWQVAL
                     KTDTAHTKARIESIDDEKMRADLDAGKVVIVAGFQGISSEGDISTLGRGGSDTSAVAL
                     AAALKADECQIYTDVDGVYTTDPRVVPEARRMDTVTFEEMIELASLGSKVLQIRSVEF
                     AGKYKVRLRVLSSLQDGGNGTLITFEEDDNMERAAVTGIAFDKNQARINVRGVPDKPG
                     VAYQILGAVADANIEVDMIIQNVGSEGTTDFSFTVPRGDYKQTLEILSERQDSIGAVS
                     IDGDDTVCKVSAVGLGMRSHVGVAAKIFRTLAEEGINIQMISTSEIKVSVLIDEKYME
                     LATRVLHKAFNLG"
     gene            complement(1539..2267)
                     /gene="rph"
                     /locus_tag="ACFOV4_001839"
     CDS             complement(1539..2267)
                     /gene="rph"
                     /locus_tag="ACFOV4_001839"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFC7619792.1"
                     /translation="MPDYIRISRAADSLRDIKITPHFLPHTDGSCLIECGNTKVICTA
                     SIDENVPPFLRGKNQGWVTAEYGMLPASTASRMRREASAGKQSGRTQEIQRLIGRSLR
                     AVVDMEKLGERQILIDCDVIQADGGTRTASITGAFVALQIAVGKLVSDGILSENPIRE
                     AVAAVSVGVVNGVPLLDLDYPEDSGCDSDVNIVMTASGKIIEIQGTAEDAPFSLDELG
                     KLVALAQKGIGELLQHQQNALSAA"
     gene            complement(2349..2813)
                     /locus_tag="ACFOV4_001840"
     CDS             complement(2349..2813)
                     /locus_tag="ACFOV4_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFC7619793.1"
                     /translation="MYKHLVVAVDGSETSINALKHAAELAGVNGARLTLVHVANPAEY
                     MALAPEFLQHESYEAAAVAQGNEVLDAAERTARELGVENTVKHLLVANKGAREMAQDL
                     VDYADENGADLLVLGTHGRTGLMHLLMGSFAETVMRQSHLPLLIIRSKAEEA"
     gene            3030..3806
                     /locus_tag="ACFOV4_001841"
     CDS             3030..3806
                     /locus_tag="ACFOV4_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HFC7619794.1"
                     /translation="MSDNALTSSRRFGGIARLYGDSALAHFSQAHVCVVGVGGVGSWA
                     VEALARTGIGRLTLIDLDNVAESNVNRQLHALTGDFGKAKVTALRERVAQINPECQVF
                     EIEDFVTEDNLPEYFGKGFDFVIDAIDQVRVKAAMAAYFVERKQPFVLSGGAGGQKNP
                     ALIQTADLSRVTHDPLLANLRYTLRKRYGFSRDTKANMRVPCVYSTENIVPPQSREAC
                     SADAAPQGLSCAGYGASMLVTASFGLYCAQAAVEHIADKK"
     gene            3944..4471
                     /locus_tag="ACFOV4_001842"
     CDS             3944..4471
                     /locus_tag="ACFOV4_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619795.1"
                     /translation="MEFVNNLVIFSFLLLMLIPIFFVVYGIYHKIRYRKIYILRISFT
                     LLVVILCSMYYIYCRYLDQQKVAYYCIDEQCISIVHLYKDYGINSPTYARIYAGKILF
                     RFQVRAKNYAELLMEDDISISKKILGNKFIIYGSLPVIYGNVDNIEVKEATGYIDRAS
                     TDYIVSRNLKFRHLY"
     gene            4642..5496
                     /locus_tag="ACFOV4_001843"
     CDS             4642..5496
                     /locus_tag="ACFOV4_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ScpA family protein"
                     /protein_id="HFC7619796.1"
                     /translation="MPPIPAPSAPSEHTVAWVFGQPVTDLPQDLFIPPDALKVVLGSF
                     QGPLDLLLYLIRKQNIDVLDIPMVKITEQYLHYIAQIETYQFDLAAEYLLMAAMLIEI
                     KSRLLLPRTEAVEDEEADPRAELVRRLLAYEQMKLAAQGLDALPRAGRDFAWAYLPLE
                     IAVEAKLPEVYITDLTQAWLGILSRAKHTRSHEVIKETISVRAQMTAILRRLNGHGIC
                     RFHDLFNPEQGAAYVVVNFIALLELAKEGLVGIVQEVGFGEIRISLNHEGAHSDGISG
                     TRGGRDVF"
     gene            5537..6745
                     /gene="pncB"
                     /locus_tag="ACFOV4_001844"
     CDS             5537..6745
                     /gene="pncB"
                     /locus_tag="ACFOV4_001844"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFC7619797.1"
                     /translation="MTGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVY
                     PLADIKEDLEVELDALCRLRFTHDELGYLRSLRFIKSDFVDYLELFQLQRRFVEVGTD
                     DKGRLNIRIEGPMIQAMFFEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEI
                     AAAQNPDEPPFLISDFGTRRRYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITP
                     IGTMAHEFLQAFQALDVRLRNFQKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLY
                     FAKLFDGLRHDSGDPYVWGDKAYAHYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKD
                     RFKTGFGIGTNLTNDMGHTPLNIVLKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQ
                     VFDVPEPETP"
     gene            6837..8555
                     /gene="argS"
                     /locus_tag="ACFOV4_001845"
     CDS             6837..8555
                     /gene="argS"
                     /locus_tag="ACFOV4_001845"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFC7619798.1"
                     /translation="MNLHQTVEHEAAAAFAAAGIAGSPVVLQPTKNAEHGDFQINGVM
                     GAAKKAKQNPRELAQKVADALAGNAVIESAEVAGPGFINLRLRPEFLARNIQTALNDA
                     RFGVAKTDKPQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLAFMGNTVVRQNHVG
                     DWGTQFGMLVAYLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQG
                     GDETVLALWKQFVDISLSHAQAVYNTLGLKLRPEDVAGESKYNDDLQAVVDDLVQKGL
                     AVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFLYASTDLACLRYRIGRLKADRLLY
                     VVDHRQALHFEQLFTTSRKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVDL
                     LTEAVERATALVKEKNPELGADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLS
                     FEGNTAPYLQYAYTRVQSVFRKAGEWDATVPTVLTEPLEKQLAAELLKFEDVLQSVAD
                     TAYPHYLAAYLYQIATLFSRFYEACPILKAEGATRNSRLQLAKLTGDTLKQGLDLLGI
                     DVLDVM"
BASE COUNT         2121 a         2434 c         2185 g         2043 t
ORIGIN      
        1 tttaatccac tatatttttt gttccaaagt caaaatatgc cgtccgaaca ttcgggcggc
       61 agacaaaacg gcactgcccg ataaaggcag tgccgttgtc cgtttcaaac cgtgaaacat
      121 cagcccaaat taaaggcttt atgcaatacc ctggttgcca gttccatgta tttttcatca
      181 atcaatacgg aaactttgat ttcggaggtg gaaatcattt ggatgttgat accctcttcg
      241 gcgagcgtgc ggaagatttt ggcggctaca ccgacgtgcg aacgcatacc caaaccgact
      301 gcagagactt tgcatacggt gtcgtcgcca tcaatagaaa ccgcgccgat actgtcttgg
      361 cgttccgaca ggatttccaa agtctgcttg taatcgccgc gcggtacggt aaaggaaaaa
      421 tcggttgtgc cttcgctgcc gacattttgg ataatcatat cgacttcgat gttggcatcg
      481 gcaaccgcgc ctaaaatctg ataggcgaca ccgggtttgt cgggtacgcc gcgcacgttg
      541 atgcgggctt ggtttttatc gaatgcgata ccggttacgg cagctctttc catgttgtcg
      601 tcctcttcaa aggtaattaa ggtgccattg ccgccgtctt gcaggctgct cagtacgcgc
      661 aggcgcactt tgtattttcc ggcgaattct actgaacgga tttgcaaaac tttcgaaccg
      721 aggcttgcca gttcgatcat ttcttcaaat gtaaccgtat ccatgcggcg cgcttcgggt
      781 acgacgcggg ggtcggttgt gtaaacgccg tctacgtcgg tatagatttg gcactcgtcg
      841 gctttgaggg ctgcggcaag cgcaacggcg gaagtgtcgg aaccgccgcg tccgagcgtg
      901 gaaatatcgc cttcactgct gatgccttgg aagccggcaa cgatgacgac tttgcctgca
      961 tcgaggtcgg cacgcatttt ttcgtcatca atgctttcga tgcgggcttt ggtgtgggcg
     1021 gtatcggttt tgagggcgac ctgccagcct gtgtagcttt tggcatccac gccgatgtct
     1081 ttcaatgcca tcgccaaaag gccgatggtt acttgttcgc cggtggacaa aaccacgtcc
     1141 aattcgcgcg gatcgggatg ctcctgcatt tcgtgcgcca acgcgaccag gcggttggtt
     1201 tcaccgctca tggcggatac gacgacgacg atgtcgtgtc cttcggcgcg ggctttggcg
     1261 acacgtttgg ccacgttttt aatgcgttcg ggcgagccta cggatgtgcc gccgtatttg
     1321 tgtacgatta acgccatgtt tcgtgctttc ttgtgtggga ttggtcgggc agcatggttt
     1381 gctggaaaag cggctattat tactattttt tacatgaagt tcaagaacgg actgcgcttt
     1441 cccacctgcc gtttgacagc ggtcagcaaa aaacctgttc tttcagattg ttgacaaaat
     1501 gccgtctgaa cggttttcag acggcatccg gacgacaatc aggcggcaga cagcgcattt
     1561 tgctggtgtt gcagcagttc gcctatgcct ttttgcgcca gtgcaaccag tttgcccaat
     1621 tcgtccaaac tgaacggcgc gtcttccgcc gtcccctgta tttcgatgat ttttcccgat
     1681 gcggtcatca cgatattcac atcactgtcg caaccggagt cttcgggata atccaaatcc
     1741 aaaagcggca cgccgttcac tacgcctact gacacagcgg caacggcttc gcggatgggg
     1801 ttttcactca aaatgccgtc tgaaaccagt ttgccgacgg cgatttgcag cgcgacaaac
     1861 gcaccggtaa tcgaagccgt acgcgtaccg ccgtctgcct gaatcacgtc gcagtcaatc
     1921 aagatttgtc gttcgccgag tttttccata tccacgaccg cgcgcagcga acgcccgata
     1981 aggcgttgga tttcttgtgt gcgcccggac tgtttgcccg ccgaagcttc gcggcgcatc
     2041 cgggaagcag ttgaggcagg cagcatcccg tattccgccg ttacccagcc ttggttttta
     2101 ccgcgcagaa acggcgggac gttttcatct atggaagcgg tacaaatcac tttggtattg
     2161 ccgcattcaa taaggcacga accgtccgta tgcggcagga aatgaggggt gattttgata
     2221 tcgcgcaggc tgtccgcggc gcgcgagatg cggatgtaat caggcatact gccctcccgt
     2281 taaaaacaga taaattaaaa agccttaaat atgaaaaatc acatttaagg ccttcaaact
     2341 gaaaatttct acgcctcttc ggctttgctg cggataatca aaagcggcag gtggctttgg
     2401 cgcattaccg tttcggcaaa actgcccatt aaaaggtgca tcagtccggt acgtccgtgc
     2461 gtgcccaaca ccagcaggtc ggcaccgttt tcatcggcat aatcaaccaa atcctgcgcc
     2521 atttcacgcg cacccttatt ggcaaccagc aggtgtttga cggtattttc cacacccagt
     2581 tcccgggcgg tgcgctcggc ggcatccaaa acttcgttgc cttgcgcgac ggcggcggct
     2641 tcgtagcttt cgtgttgcaa aaattcgggg gcgagcgcca tatattcggc aggattggca
     2701 acgtgtacca aagtcagacg cgcaccgttg accccggcaa gctcggcggc atgtttcagg
     2761 gcattgatgg acgtttcact gccgtcaacg gcaacaacca aatgtttgta catatcgtat
     2821 tctccttttg caccgcctcg cggtgccctc ttgtcggatg ggcgcaggga cagtttgcgc
     2881 tgtttcatta tagacccgcc gtcgggcttt atacaacagc cgaacagccc gaccgctttc
     2941 cagtataata tgccgcttcc gtgcagtcag gcattttttg ccggctttcg ttcacttttt
     3001 gatttgacgc aatcttgcag gattcgacca tgtccgacaa cgctttgacc tcttcgcgac
     3061 gcttcggcgg catcgccaga ctctacggag actctgcctt ggcgcacttt tcacaggcac
     3121 acgtctgcgt agtcggcgtg ggcggtgtcg gctcgtgggc ggtcgaggct ttggcgcgga
     3181 cgggcatcgg acgtttgact ttgattgatt tggacaacgt tgccgaatcg aatgtcaacc
     3241 gccagctgca cgccctgacc ggagacttcg gcaaagcaaa agttaccgcc ttgcgcgaac
     3301 gcgtcgccca aatcaaccca gaatgccaag tgtttgaaat tgaagatttc gttaccgaag
     3361 acaatttgcc ggaatacttc ggaaaaggtt ttgatttcgt catcgacgcg atcgaccaag
     3421 tgcgcgtcaa agcagcaatg gcggcttatt ttgtggaacg caaacaaccg tttgtcctca
     3481 gcggcggcgc gggcggacaa aaaaatccgg cgttaatcca aaccgccgat ttgagccgcg
     3541 taacccacga cccgctgctt gccaacctgc gctacacctt gcggaaacgc tacggattca
     3601 gccgcgatac gaaagcaaat atgcgcgtgc cttgcgtgta ttcgaccgaa aatatcgtgc
     3661 cgccgcagtc tagggaggct tgttcggcag atgccgctcc gcaaggcttg tcgtgcgccg
     3721 gctacggtgc aagcatgctc gttaccgctt cgttcgggct atattgcgca caggcggcgg
     3781 tggaacacat cgcagacaaa aaataagcaa tgccgtctga aacaggattc agacggcatt
     3841 tgaacaaact atggttatga tttaagacaa caaaggatac ggataaaaaa taacataaaa
     3901 tatatgattc ctaataatat accaagtatc ggagagctat ttaatggaat tcgttaataa
     3961 tttagttatt ttttcatttt tattactaat gcttattccg atattttttg tagtatatgg
     4021 tatataccat aagatacgtt atcgcaaaat atatatccta agaataagtt ttacattatt
     4081 agtggtaata ctttgcagta tgtattacat atattgccgt tatcttgacc aacaaaaagt
     4141 agcttattat tgcatagatg aacaatgtat ttctattgtt catctataca aagattatgg
     4201 tataaactct cccacatatg cgagaattta cgcaggaaaa atattgttta gatttcaagt
     4261 aagagctaaa aattacgctg aattacttat ggaagatgat atatcaatta gtaaaaaaat
     4321 tttggggaat aaatttatca tttatgggtc gctacctgta atatacggta atgtagataa
     4381 tattgaagta aaagaagcta ctggttatat agatagagcc agtactgatt atattgtctc
     4441 aagaaactta aaattcagac atttatatta attaagaggt tttagcaaga ccgtattcac
     4501 aacctgctcc ttttcaaaac atttgcattt aaaagccgtt ataatgccgt ctgaacatct
     4561 gcccgaccac attatgcgtg aatgccggca gattgttttc ttttgtaaac ttatattaaa
     4621 atccacttac cgattcacgc catgccgccc atccctgccc catccgcacc atccgagcac
     4681 actgtcgcat gggtattcgg ccaacccgtt accgatttgc cccaggattt gtttattccg
     4741 cccgatgcat tgaaagtcgt attgggcagt tttcaaggcc ctttggatct actgctgtat
     4801 ctgatccgca agcagaacat cgatgttctc gatattccga tggtgaagat taccgagcag
     4861 tatctgcact acatcgccca aatagaaacc tatcagtttg atttggcggc ggaatatctt
     4921 ttgatggcag caatgctgat tgaaatcaaa tcgcgcctgc tgctgccgcg taccgaagcc
     4981 gtcgaagacg aagaagccga cccgcgtgcc gagttggtgc gccgcctgtt ggcttatgaa
     5041 cagatgaagc tggcggcaca agggttggat gcgcttcctc gtgcgggccg ggatttcgcg
     5101 tgggcgtacc tgcctctgga aattgccgtc gaagccaagc tgcccgaagt ctatattacc
     5161 gacttgacgc aagcgtggct gggtattttg tctcgggcaa aacacacgcg cagccacgaa
     5221 gtaatcaaag aaaccatctc cgtgcgcgcg caaatgacgg caatcctgcg ccgtttgaac
     5281 ggacacggga tatgcaggtt tcacgacctg ttcaatcccg aacagggcgc ggcttacgtg
     5341 gtcgtcaact tcatcgcact gttggagctt gccaaagaag gtttggtcgg aatcgtacag
     5401 gaagtcggtt tcggagaaat ccgaatcagc ctcaatcatg agggggcaca ttcagacggc
     5461 atttccggca cacggggcgg gcgcgatgtg ttctaatacg ccccaagccg ccaccaaaaa
     5521 tcgggagaca cgccatatga ccggcatcat acattcgctg cttgacaccg acctctacaa
     5581 attcactatg ctgcaagtag tcctgcacca gtttccgcag acgcacagcc tttacgaatt
     5641 ccgctgccgc aacgcctcga ccgtctatcc gcttgccgac atcaaagaag acttggaagt
     5701 cgaactcgac gcgctctgcc ggctgcgctt cacccacgac gaactcggct atctgcgctc
     5761 cctgcgtttc atcaaaagcg actttgtcga ttatctcgaa ctcttccagc tccaacgccg
     5821 ctttgtcgaa gtcggcacag acgataaagg ccgtctgaac atccgcatcg aaggtccgat
     5881 gatacaggcg atgttctttg aaatcttcat cctcgccatt gtcaacgaac tttacttccg
     5941 ccgcctggaa acccctgcag tcatagaaga aggcgaacgc cgccttcaag ccaaagccgc
     6001 gcgcctcaaa gaaatcgccg ccgcacaaaa ccccgacgaa ccgcccttcc tgatttccga
     6061 cttcggcacg cgccgccgct acaagctcgc gtggcaggaa cacgtcatcc gcaccctgct
     6121 cgaagccgcc ccaagcatcg tgcgcggcac cagcaatgtc tttctcgcca aaaaactcgg
     6181 catcaccccc atcggcacca tggcgcacga attcctccaa gccttccagg ccctcgacgt
     6241 acgcctgcgg aatttccaaa aggccgcgct cgaaagctgg gtgcacgaat accggggcga
     6301 tttgggcgtt gccctgaccg acgtggtcgg tatggatgct ttcctgcgcg atttcgacct
     6361 ctatttcgcc aaactcttcg acggtttgcg ccacgacagc ggcgaccctt atgtttgggg
     6421 cgacaaagcc tacgcccact atcaaaagct caaaatcgac agccgcacca aaatgctgac
     6481 cttctccgac gggctggaca tcgaacgctc ttgggcattg caccaatatt tcaaagaccg
     6541 cttcaaaacc ggcttcggca tcggcaccaa cctcaccaac gatatggggc atacgccctt
     6601 gaatatcgtg ttaaaactgg tcgaatgcaa cggccagtcc gtcgccaagc tgtccgactc
     6661 tccgggcaaa accatgacca acaacagcac cttcctcgcc tacctgcgcc aagtgttcga
     6721 cgtacccgaa cccgaaacgc cgtaaaccgg cagaaaaagc gcacaattcc tgtttctgcc
     6781 gcataaaatc ttttaaaata ccgcctgatt tgaatttaac cgaaagaccg aacttcatga
     6841 acctacatca aaccgtcgaa cacgaagccg ccgccgcctt tgccgccgca ggcatcgccg
     6901 gcagccccgt tgtcttgcag ccgaccaaaa atgccgaaca cggcgatttc caaatcaacg
     6961 gtgtgatggg ggcggcgaaa aaagccaaac aaaatccgcg cgaattggcg caaaaggttg
     7021 ccgacgcatt ggcaggcaac gccgtcatcg aaagcgcgga agtcgccggt ccgggcttca
     7081 tcaacctgcg cctgcgcccc gaatttctcg cccgaaacat tcagacggcc ttaaacgacg
     7141 cgcgtttcgg cgtggcaaaa accgacaagc cgcaaaccgt cgttatcgac tattcttcgc
     7201 ccaatctggc caaagaaatg cacgtcggac acctccgttc cagcatcatc ggcgacagca
     7261 tttcgcgcgt gttggcattt atgggcaaca ccgtcgtccg tcaaaaccac gtcggcgact
     7321 ggggtacgca gtttggtatg ttggtcgctt atttggtcga gcagcaaaaa gacaatgccg
     7381 cattcgagct ggcggatttg gagcagtttt accgcgccgc caaagtgcgc tttgacgaag
     7441 atcctgcctt cgccgacacc gcgcgcgaat acgttgtgaa gctgcaaggc ggtgatgaaa
     7501 ccgtattggc attgtggaaa cagtttgtcg atatttcgct ctcgcacgcc caagccgttt
     7561 ataacacgct gggcttgaag ctgcgccccg aagacgtggc gggcgaatcg aagtacaacg
     7621 acgatttgca agccgtggtc gatgatttgg ttcaaaaagg tctggcggtc gaagacgacg
     7681 gcgcgaaagt tgtgttcttg gacgagttta aaaacaaaga gggcgaaccc gccgcattta
     7741 tcgtgcaaaa acaaggcggc ggcttccttt atgcttccac cgacttggcg tgtttgcgct
     7801 accgcatagg ccgtctgaaa gccgaccgcc tgctgtacgt cgtcgaccac cgccaagccc
     7861 tgcacttcga gcaactcttt accacttccc gcaaagccgg ctatctgccg gaaaacgtcg
     7921 gcgcggcatt tgtcggcttc ggcacgatga tgggcaaaga cggcaagccg tttaaaacgc
     7981 gcagcggcga caccgtgaaa ctggtcgatc tgctgaccga agccgtcgaa cgcgccaccg
     8041 ctttggtgaa agagaaaaat cccgaattgg gcgcggacga agccgctaaa atcggcaaaa
     8101 ccgtcggcat cggcgcggtc aaatatgccg acttgagcaa aaaccgtacc agtgattatg
     8161 tgttcgattg ggacgctatg ctctcgtttg aaggcaacac cgccccctac ctgcaatacg
     8221 cctacacccg cgtgcaaagc gtgttccgca aagccggcga atgggacgca accgtgccaa
     8281 ccgttttgac cgaacctttg gaaaaacaac tagccgccga gctgctgaaa ttcgaagacg
     8341 tgctgcaaag cgtggcggac acggcgtatc cgcactacct cgccgcctac ctctaccaaa
     8401 ttgccaccct gttcagccgc ttctacgaag cctgcccgat tttgaaagcc gaaggcgcaa
     8461 cccgcaacag ccgcctgcaa ctggcgaagc tgaccggcga cacgctgaaa caaggcctgg
     8521 atttgctggg cattgatgtg ttagacgtaa tgtaaaaccg caccgcccga ttgcggacaa
     8581 cagccccgca atcaaccggc ggaccatcct catccgaatc tgaaaaaagc ggcgcgatac
     8641 accgtatccg ccgcccctcc caaaatgcga aacagacaaa cgccaagcaa gcaagcaagc
     8701 aagcaagcaa gcaaaaaatt ataaccccct tcctgccgac gcacgcactt tccgcgcggc
     8761 gcattcccct tttcccgccc ctc
//
LOCUS       DAXISH010000075         8760 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.075, whole genome shotgun sequence.
ACCESSION   DAXISH010000075 DAXISH010000000
VERSION     DAXISH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8760
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.075"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..396)
                     /locus_tag="ACFOV4_001846"
     CDS             complement(<1..396)
                     /locus_tag="ACFOV4_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HFC7619799.1"
                     /translation="MKQLAMYINGRFENDFNGEWRDVLNPSTEETIAREPKGGKADVD
                     RAVAAARAAQPAWERLPAVERGAYLRKIAQGIRGRADELTDTIVAEGGKTKDLARVEV
                     MFTADYLDYQAEWARRYEGEIIQSDRPREN"
     gene            complement(431..631)
                     /locus_tag="ACFOV4_001847"
     CDS             complement(431..631)
                     /locus_tag="ACFOV4_001847"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619800.1"
                     /translation="MDTVGSLAIGYATGGNAGAFTDANADWNNRQLHSSEYKLAEQYA
                     DIVASRLNISKETCTAIYLGIN"
     gene            complement(640..1029)
                     /locus_tag="ACFOV4_001848"
     CDS             complement(640..1029)
                     /locus_tag="ACFOV4_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619801.1"
                     /translation="MLYKCKIKKLDNTIEEAVLIEINGYELHCFISYCPFKIFENQFY
                     EVELSYEIFNDYILDKSTSNIGFRKIDDSFKYEITAELKNNHLTLQNIQFEEDEYLVN
                     YSYLDNCLVTLTADRISVSFIREIQAA"
     gene            complement(1030..1206)
                     /locus_tag="ACFOV4_001849"
     CDS             complement(1030..1206)
                     /locus_tag="ACFOV4_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619802.1"
                     /translation="MSGYVQFLGTDSKGQSKFIFVGTNENGSITTIHTKSGKDFWRTL
                     NNNPKNKTIYPKAR"
     gene            complement(1237..2154)
                     /locus_tag="ACFOV4_001850"
     CDS             complement(1237..2154)
                     /locus_tag="ACFOV4_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC7619803.1"
                     /translation="MEKAEHLNSSRFVNLVKSGGGSYMEGSYRFDTLSNGISIHGGTV
                     TARCDFCSSRLAEPYVSFVLLLEGSLNFGINRSRFQIDADGGKVILISVGEEVLFSRY
                     LYRGGKTVKMTIKGMEQWLLRPEYACFTPILYREPVRIWNLSPNLRGLAASCLQAVPK
                     GHLGETLRREADVLRLLSDLWDTVSDGIGPAAGQTAEADAMPSEDFSRTLNAAFADGA
                     HQVNRLADALNISERTLQRRMRDHFGITASEWLHHKQMQHALYLLQNGGKSIGETAYL
                     CGYRHVSSFTQAFRQYFGSTPAETKKENR"
     gene            2327..3127
                     /locus_tag="ACFOV4_001851"
     CDS             2327..3127
                     /locus_tag="ACFOV4_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC7619804.1"
                     /translation="MSPSPFIEMKDVAFAYGDRPILNDINFSIPQGNFAAVMGGSGSG
                     KTTLMRLITGQIRPQSGQVLIEGRDLSGFSADELYEHRRRMGVLFQHGALFTDLSVFD
                     NIAFPMRELTQLPEAVIRDLVLLKLNAVGLRGVENLMPSELSGGMSRRVALARTIALD
                     PEIMLYDEPFTGLDPISLGVIAHLISRVNKALRSTSIMVTHDIEKSLEIVDQVIFLAH
                     GEIMFSGSPQEMRELDSPWVRQFVGGLADGPVAYRYPAQTSLQQDLLG"
     gene            3175..3951
                     /gene="mlaE"
                     /locus_tag="ACFOV4_001852"
     CDS             3175..3951
                     /gene="mlaE"
                     /locus_tag="ACFOV4_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HFC7619805.1"
                     /translation="MNFIRSVGAKTLGLIQSLGSITLFLLNILAKSGTAFVRPRLSVR
                     QVYFAGVLSVLIVAVSGLFVGMVLGLQGYTQLSKFKSADILGYMVAASLLRELGPVLA
                     AILFASSAGGAMTSEIGLMKTTEQLEAMNVMAVNPVARVVAPRFWAGVFSMPLLASIF
                     NVAGIFGAYLVGVSWLGLDSGIFWSQMQNNITIHYDVINGLIKSAAFGVAVTLIAVHQ
                     GFHCVPTSEGILRASTRTVVSSALTILAVDFILTAWMFTD"
     gene            4002..4496
                     /gene="mlaD"
                     /locus_tag="ACFOV4_001853"
     CDS             4002..4496
                     /gene="mlaD"
                     /locus_tag="ACFOV4_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015914 - phospholipid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HFC7619806.1"
                     /translation="MKKNILEFWVGLFVLLGVAAVGFLAFRVAGGAAFGNSGKTYTVY
                     ADFSDIGGLKANAPIKSAGVLVGRVGSIELDPKSYQAKVRLDLDSKYQFSSDVSAQIL
                     TSGLLGEQYIGLQQGGDTENLAAGDTISVTSSAMVLENLIGKFMTSFAEKNADGGNAE
                     KAAE"
     gene            4533..5123
                     /locus_tag="ACFOV4_001854"
     CDS             4533..5123
                     /locus_tag="ACFOV4_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HFC7619807.1"
                     /translation="MKKSSLISALGIGILSIGMAFAAPADAVSQIRQNATQVLSILKN
                     GDANTARQKAEAYAIPYFDFQRMTALAVGNPWRTASDTQKQALAKEFQTLLIRTYSGT
                     MLKLKNANVNVKDNPIVNKGGKEIIVRAEVGVPGQKPVNMDFTTYQSGGKYRTYNVAI
                     EGASLVTVYRNQFGEIIKAKGVDGLIAELKAKNGGK"
     gene            5174..5452
                     /locus_tag="ACFOV4_001855"
     CDS             5174..5452
                     /locus_tag="ACFOV4_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HFC7619808.1"
                     /translation="MHTELKNGILHIGGDITVKTLTAAAFTRFRQQCRLKDTCAVDLS
                     GVGRADSACVSLLLEVLRGCKGSVRLTGIPESVRALSELYEIKDWLKS"
     gene            5449..6276
                     /locus_tag="ACFOV4_001856"
     CDS             5449..6276
                     /locus_tag="ACFOV4_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VacJ family lipoprotein"
                     /protein_id="HFC7619809.1"
                     /translation="MKKTAYAFLLLIGFASAPAFAETRPADPYEGYNRAVFKFNDQAD
                     RYIFAPAARGYRKVAPKPVRAGVSNFFNNLCDVVSFGSNILRLDIKRASEDLVRVGIN
                     TTFGLGGLIDIAGAGGIPDNKNTLGDTFASWGWKNSNYFVLPVLGPSTVRDALGTGIT
                     SVYSPKNIVFRTPVGRWGTTAVSAVSTREGLLDLTDSLDEAAIDKYSYTRDLYMKVRA
                     RQTGATPAEGTEDNIDIDELVESAETGAAETAVQEDSVSETQAEAAGEAETQPGTQP"
     gene            6401..6763
                     /locus_tag="ACFOV4_001857"
     CDS             6401..6763
                     /locus_tag="ACFOV4_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003681812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VacJ"
                     /protein_id="HFC7619810.1"
                     /translation="MYEVNRSVFVLIPLEPFWNWLQTLPGNHLDGLTLEDIQADANSY
                     LVRPCETADEVWDEIEARFEDIFAAELADWCEDEREWPALDADIFNEWFDIQLSTVIT
                     DLEHEPLAREAFQPINLN"
     gene            6763..7146
                     /locus_tag="ACFOV4_001858"
     CDS             6763..7146
                     /locus_tag="ACFOV4_001858"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFC7619811.1"
                     /translation="MKLTVRNYHLDGYGHVNNARYLEFFEEARWAFFEERGLLHELAG
                     LILIVARIDIRYSRPAVEGDVLQFSCRLKTPGTRRIVLTQTITLPNGKTAAEADITLM
                     PVHAATQRTVSLPATLARALEALSE"
     gene            7143..7631
                     /locus_tag="ACFOV4_001859"
     CDS             7143..7631
                     /locus_tag="ACFOV4_001859"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin family protein"
                     /protein_id="HFC7619812.1"
                     /translation="MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNA
                     DLQGKVTLINFWFPSCPGCVSEMPKIIKTANDYKNKNFQVLAVAQPIDPIESVRQYVK
                     DYGLPFTVMYDADKAVGQAFGTQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTAL
                     AQ"
     gene            complement(7714..7842)
                     /locus_tag="ACFOV4_001860"
     CDS             complement(7714..7842)
                     /locus_tag="ACFOV4_001860"
                     /inference="COORDINATES: protein motif:HMM:NF025953.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFC7619813.1"
                     /translation="MAGVTVGRGSVVGAGAVVTKDIPPYSLAAGNPAVVKKNLPEG"
     gene            complement(7848..8228)
                     /locus_tag="ACFOV4_001861"
     CDS             complement(7848..8228)
                     /locus_tag="ACFOV4_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-o"
                     /protein_id="HFC7619814.1"
                     /translation="MGSKFFFLLLRFAGSGLPPSHMRGIGIVGRRVRGFLARRVSPHI
                     GRGVNIERGAYVFPDTVLGDGSGIGANCEICRGLVVGKNVMMEPECLFYSNNHKFDRS
                     KNALRATRKSVRLRWRTMSGRGTG"
     gene            8466..8681
                     /gene="rpmE"
                     /locus_tag="ACFOV4_001862"
     CDS             8466..8681
                     /gene="rpmE"
                     /locus_tag="ACFOV4_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003681847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HFC7619815.1"
                     /translation="MKQGIHPNYHEVNVTCSCGNKFATKSAMEKENFNIEVCSLCHPF
                     YTGTQKIVDTTGRVDKFNNKFGNLFKR"
BASE COUNT         2094 a         2448 c         2123 g         2095 t
ORIGIN      
        1 attttcgcgc gggcggtcgc tttggatgat ttcgccttcg taacgacgcg cccattcggc
       61 ttggtaatcg agatagtcgg cggtaaacat gacttccacg cgcgccaagt ctttggtttt
      121 gccgccttcg gcaacgatgg tgtcggtcag ctcgtcggcg cgtccgcgta tgccttgggc
      181 gattttgcgc aaatacgcgc cgcgttcgac cgcaggcagg cgttcccaag ccggttgcgc
      241 cgcgcgtgcc gccgccacag ctcggtcaac gtctgctttt ccgcctttgg gttcgcgggc
      301 gatggtttct tcggtggatg ggttcaatac gtcgcgccat tcgccgttga aatcgttttc
      361 aaagcgtccg ttgatgtaca tggccaattg tttcatttcg ggttctccag ttttgtagtc
      421 agatgtagtc ttagtttatt cccaaataaa ttgccgtaca agtttctttt gaaatgttta
      481 gacgagaagc tactatgtct gcatattgtt ctgctaattt atattcactc gaatgcaact
      541 gccgattatt ccaatctgca ttcgcatcag taaaagcccc agcattgccg cctgtggcat
      601 aaccaatcgc taaactgcca acggtatcca caacaggttt caggctgcct gaatttctct
      661 aataaatgaa acacttattc tatcagccgt taatgtaacc aaacaattat caagataaga
      721 gtagtttact aaatactcat cttcttcaaa ttgtatattt tgtagggtta gatgattatt
      781 ttttaattct gccgttattt catacttgaa actatcatct atttttctaa atccaatatt
      841 tgaagttgat ttatccagta tgtaatcatt aaagatttca taggataatt ccacttcata
      901 aaattgattt tcaaatattt tgaatgggca gtacgatata aaacaatgta gttcataacc
      961 atttatttca atcaatactg cctcttcaat ggtgttatct aactttttga ttttacattt
     1021 atataacatt tatcttgcct ttggataaat tgttttgttt tttggattgt tattcaaagt
     1081 tctccaaaag tcttttcctg attttgtatg tatcgtggta atactaccat tttcattggt
     1141 tccaacaaaa ataaatttag attgaccttt ggaatcagta cccaaaaact gaacatatcc
     1201 agacatgcgg atttcgggtt ttaaatcaaa tgcggcttac cggttttctt ttttggtttc
     1261 cgcaggcgtg ctgccgaaat attgcctgaa tgcctgagta aagctggaaa cgtggcggta
     1321 gccgcacaaa tacgcggttt cgcctatgct tttgcccccg ttttgcaaca ggtagagcgc
     1381 gtgctgcatt tgtttgtggt gcagccactc gcttgcggta atgccgaaat ggtcgcgcat
     1441 acggcgttgc agcgtccttt cgctgatgtt cagcgcgtct gccagccggt tgacttggtg
     1501 tgcgccgtcg gcaaacgcgg catttagggt gcggctgaag tcttcagacg gcatagcgtc
     1561 tgcttccgcc gtttgccccg ccgccggccc gatgccgtct gaaaccgtgt cccacaaatc
     1621 cgacagcagc cgcaaaacgt ccgcctcgcg gcgcaatgtt tcgcccaaat gcccctttgg
     1681 gacggcttgc aggcaggatg ccgccaaacc gcgcaggttt ggggacaaat tccatattct
     1741 gaccggttcg cggtaaagta tgggtgtaaa acacgcatac tccggacgca gcagccattg
     1801 ctccatacct ttaattgtca ttttgaccgt tttgccgcct cgataaagat agcggctaaa
     1861 caggacttct tccccgactg aaatcaggat gaccttgccg ccgtccgcat cgatttggaa
     1921 tcggctccgg ttgatgccga agttcaaaga gccttccagc aaaagcacga acgacacata
     1981 aggttcggcg aggcggctgc tgcaaaaatc gcaccgtgcc gttaccgtgc cgccgtggat
     2041 ggaaatgccg ttggacaaag tatcgaaacg gtagctgccc tccatatagc tgccgccgcc
     2101 gcttttgacc agattgacga accggctgct gttcaaatgt tctgcttttt ccatagtttt
     2161 ctgataaagg ttatcatttg aaagataaca tttttcgcca cagcaaacaa tccgccgccg
     2221 acaacggcat tttcacaaca cttaccgtcc gtatgccgtc tgaaaattgc ccgtcttccc
     2281 gataagcctt aaaatacacg ccgtcaaacc taccgtccgt ccgtacatga gcccatcccc
     2341 ctttatcgaa atgaaagacg tcgccttcgc gtatggcgac cgcccgattc tgaacgacat
     2401 caatttcagt attccgcaag gtaattttgc cgccgtgatg ggcggttcgg gcagcggcaa
     2461 aaccacgctg atgcgactga ttacaggaca gattcgtccg cagtccgggc aggttttgat
     2521 tgaaggacgt gatttgtcgg gcttttcggc tgacgagttg tatgaacacc gccgccgtat
     2581 gggcgtattg ttccaacacg gcgcgctgtt taccgatttg tctgtatttg acaatattgc
     2641 ttttccgatg cgcgaactga cgcaactgcc ggaagcggtg attcgagatt tggttttgtt
     2701 gaaactgaac gcggtcggtc tgcgcggtgt agaaaacctg atgccgtccg agttgtccgg
     2761 cgggatgtcg cgccgcgtcg cgcttgcccg cacgattgcg ctcgaccccg aaattatgtt
     2821 gtacgacgaa ccgtttaccg gtctcgatcc gatttccttg ggcgtgattg cccacttgat
     2881 cagccgcgtc aacaaggctt tgcgttcgac cagtattatg gtcacgcacg acattgaaaa
     2941 atctttggaa atcgtcgatc aggtgatttt cttggcgcac ggcgaaatta tgttctccgg
     3001 ctcgccgcag gaaatgcgcg aactggattc gccttgggtg cgccagtttg tcggcggctt
     3061 ggcagacggc cccgtggcat accgttatcc ggcgcaaacg tcgttgcagc aggatttgct
     3121 cgggtaaatg agccggtgcc gtctgaaacc gttgaacttt acatatagaa atttatgaac
     3181 tttatccgtt ccgtcggggc gaaaaccctc ggccttattc aatccctcgg cagtattacg
     3241 ctgtttctgc tgaacatctt ggcgaaatcc ggtacggctt tcgtccgtcc gcgcctgagc
     3301 gtgcgccaag tgtatttcgc cggcgtgctg tcggtgctga ttgttgccgt ttcggggctg
     3361 ttcgtcggta tggttttggg tttgcagggt tatacgcagt tgtcgaaatt caaatccgcc
     3421 gatattttgg gctatatggt cgcggcttcg ctattgcgcg agctgggtcc ggtattggca
     3481 gcgattttgt ttgccagcag cgcgggcggt gcgatgacca gcgaaatcgg tctgatgaaa
     3541 acgaccgaac agctcgaagc gatgaatgtg atggcggtaa accctgtcgc ccgcgtggtt
     3601 gcgccgcgct tttgggcggg cgtgttttcc atgccgcttt tggcttcgat tttcaacgtg
     3661 gcgggcattt tcggtgcgta tttggtcggt gtaagctggc tgggcttgga cagcggcatt
     3721 ttctggtcgc aaatgcagaa caacatcacg atacattacg atgtaatcaa cggtctgatt
     3781 aaatccgccg cgttcggcgt ggcggtaacg ctgattgccg tgcatcaggg cttccattgc
     3841 gtcccgactt cggaaggcat tttgcgcgcc agcacgcgca cggtggtttc gtccgccctg
     3901 acgattttgg cggtcgattt tatattgacc gcgtggatgt ttacagattg acaggccgtc
     3961 tgaagacgaa acgcggaaca tcggatattc aaggaacttt aatgaaaaag aacatattgg
     4021 aattttgggt cggactgttt gtcctgctcg gcgtggcagc ggtcggcttt ctcgctttcc
     4081 gcgtggcagg cggcgcggcc ttcggcaatt ccggcaagac ttataccgta tatgccgatt
     4141 tcagcgacat cggcggactg aaggccaacg cgccgatcaa atccgcaggc gtattggtcg
     4201 gacgcgttgg ttccatcgag cttgacccga aatcctatca ggcgaaagtc cgtctcgatt
     4261 tggacagcaa atatcagttc agtagcgacg tttccgcaca aatcctgact tcgggacttt
     4321 tgggcgagca gtacatcggg ctgcagcagg gcggcgacac ggaaaacctt gctgccggcg
     4381 acaccatctc cgtaaccagt tctgcaatgg ttctggaaaa ccttatcggc aaattcatga
     4441 cgagttttgc cgagaaaaat gccgacggcg gcaatgcgga aaaagccgcc gaataaacgt
     4501 atgccatcat attcaaacta ggacacttaa tcatgaaaaa atcctccctc atcagcgcat
     4561 tgggcatcgg tattttgagc atcggcatgg catttgccgc ccctgccgac gcggtaagcc
     4621 aaatccgtca aaacgccact caagtattga gcatcttaaa aaacggcgat gccaacaccg
     4681 cccgccaaaa agccgaagcc tatgcgattc cctatttcga tttccaacgt atgaccgcat
     4741 tggcggtcgg caacccttgg cgcaccgcgt ccgacacgca aaaacaagcg ttggccaaag
     4801 aatttcaaac cctgctgatc cgcacctatt ccggcacgat gctgaaatta aaaaacgcca
     4861 acgtcaacgt caaagacaat cccatcgtca ataaaggcgg caaagaaatc atcgtccgcg
     4921 ccgaagtcgg cgtacccggg caaaaacccg tcaacatgga cttcaccacc taccaaagcg
     4981 gcggtaaata ccgtacctac aacgtcgcca tcgaaggcgc gagcctggtt accgtgtacc
     5041 gcaaccaatt cggcgaaatt atcaaagcga aaggcgtgga cggactgatt gccgagttga
     5101 aagccaaaaa cggcggcaaa taaccgacaa accataccgt ccgagggcgg tatgggtttt
     5161 ccgagcaaac gctatgcata cagaactcaa aaacggaata ttgcacatcg gcggcgacat
     5221 caccgtcaaa accctgaccg ccgccgcttt tacccgcttc agacagcaat gtcgtctgaa
     5281 agacacctgc gcggttgatt tgagcggcgt cggacgcgcc gattccgcct gcgtgtcgct
     5341 gctgctcgaa gtgctgcgcg gttgcaaagg cagcgtcagg ctgaccggca ttcccgaatc
     5401 cgtgcgcgcg ctgtccgaac tgtacgaaat caaagactgg ctgaaatcat gaaaaaaacc
     5461 gcctatgcct tcctcctgct gatcgggttc gcttccgccc ctgcatttgc cgaaacccgc
     5521 cccgccgacc cttatgaagg ctacaaccgc gccgttttca aattcaacga ccaagccgac
     5581 cgctacattt tcgcccctgc cgcgcgcggc taccgcaaag ttgcgccgaa acccgtccgc
     5641 gccggcgtgt ccaatttttt taacaacctg tgcgacgtgg tcagcttcgg tagcaatatc
     5701 ttgcgcttgg acatcaaacg cgcaagcgaa gaccttgtcc gcgtcggcat caacaccact
     5761 ttcggtttgg gcgggcttat cgacatcgcc ggcgcgggcg gcattcccga caataaaaac
     5821 accttgggcg acacgtttgc ttcgtgggga tggaaaaaca gcaattattt cgtgttgccc
     5881 gtcttagggc cgtccaccgt ccgcgacgcg ctcggcacgg gtattacctc cgtttattcg
     5941 cccaagaata tcgtcttccg cacccctgtc ggacgctggg gcacgactgc cgtatccgcc
     6001 gtcagtacgc gcgaaggtct gctcgatttg accgacagtc tggacgaagc cgccatcgac
     6061 aaatacagct acacgcgcga cctctatatg aaagtccgtg cgcggcagac cggtgcaaca
     6121 cctgccgaag gtacggaaga taacatcgac atcgacgaat tggtcgaaag tgccgaaacc
     6181 ggcgcggcgg aaactgccgt tcaagaagat tccgtatccg aaacacaggc agaagcagca
     6241 ggggaagccg aaacgcaacc tggaacacaa ccttaaagcc atgccgtctg aaaatccgtg
     6301 ttcggacggc attcccttct gtcggaacgg acagtccgaa accacagatt gggctataat
     6361 ctcttttttg cgcataccgc gcgacagcaa aggaaaaacc atgtacgaag tcaaccgcag
     6421 cgtattcgtc ctcatccctt tagaaccttt ttggaactgg ctgcaaaccc tgccgggcaa
     6481 ccacctcgac ggactgactc ttgaagacat ccaagccgac gccaattcct accttgtccg
     6541 cccgtgcgaa accgccgacg aagtatggga cgaaatcgaa gcccgttttg aagacatttt
     6601 cgccgccgaa cttgccgact ggtgcgaaga cgaacgcgag tggcctgcgc tcgatgccga
     6661 cattttcaac gaatggttcg acatccagct ttctaccgtc atcaccgacc tcgaacacga
     6721 accgcttgcc cgcgaagcct tccaacccat caacctgaac tgatgaagct gaccgtccgc
     6781 aactaccatc tcgacggcta cggccatgtc aacaatgcgc gctacctcga atttttcgaa
     6841 gaagcgcgct gggcgttttt tgaagaacgc ggactgctgc acgagttggc aggcctcata
     6901 ctgattgtcg cccgcatcga catccgatac agccgccccg ccgtcgaagg cgacgtattg
     6961 cagttttcat gccgcctgaa aacccccggc acgcgccgta ttgtgctgac ccagacgatt
     7021 acactgccaa acggcaaaac cgccgcagaa gccgacatca ccctgatgcc cgtccacgcc
     7081 gccacacaac gcaccgtcag cctgcccgcc acccttgccc gcgcattgga agccttgtcc
     7141 gaatgaaaaa aatactcacc gccgccgtcg tcgcactgat cggcatcctc cttgccatcg
     7201 tcctcatccc cgacagcaaa accgcgcccg ccttctccct gcccgacctg cacggaaaaa
     7261 ccgtttccaa cgccgacctg caaggcaaag taaccctgat taatttttgg tttccctcct
     7321 gtccgggttg tgtgagcgaa atgcccaaaa tcattaaaac ggcaaatgac tataaaaaca
     7381 aaaacttcca agtccttgcc gttgcacaac ctatcgatcc gatagaaagc gtccgccaat
     7441 atgtcaaaga ctacggtttg ccgtttaccg tcatgtatga tgcggacaaa gctgtcggac
     7501 aggcgttcgg cacacaggtt tatccgactt ctgtcctcat cggcaaaaaa ggcgaaatcc
     7561 tcaaaactta tgtcggcgaa cccgatttcg gcaaactcta ccaagaaatc gataccgcgc
     7621 tggcacaata gcgatgccgt ctgaagcgca aaaaaaacag aaacgatgtt cctgtttttt
     7681 cagatcatcc gccccgacac gttcagacgg cattcaacct tccggcagat tctttttcac
     7741 cactgccgga ttgcctgccg ccaaagagta gggcggaatg tcttttgtaa ccaccgcgcc
     7801 tgcgcccacg accgaaccgc gtccgacggt tacgcccgcc attacaatca ccctgtgccc
     7861 cggccagaca tcgtcctcca acgtaatcgg acggatttcc gtgtagccct caaagcgttt
     7921 tttgaacggt caaacttgtg gttatttgaa taaaacagac attccggctc catcatcaca
     7981 tttttgccga ccaccagccc acggcagatt tcacagtttg ccccgatgcc cgagccgtcg
     8041 cccaaaaccg tatccggaaa cacatacgcc ccgcgttcga tattgacccc gcgtccgata
     8101 tgcggagaaa cccgccgcgc caaaaaaccg cgcacccgtc tgccgacgat gccgatgccg
     8161 cgcatatgtg acggcggcaa ccccgaaccg gcaaaacgca gcagcaggaa aaagaatttt
     8221 gatcccatca aacctccctc aaaagaactt tttatagtgg attaacaaaa atcaggacaa
     8281 ggcgacgaag ccgcagacag tacagatagt acggcaaggc gaggcaacgc tgtactggtt
     8341 tttgttaatc cactatacat tttatcgaat atcctcttga cgaaacaaca gaaaatagcg
     8401 agaatgccga gcttgtctga agcataggta catcccctat gcccgctttt ttgaaaggaa
     8461 atcaaatgaa acaaggtatt cacccgaact accacgaagt caacgttacc tgctcttgcg
     8521 gcaacaaatt cgcaaccaaa tccgcgatgg aaaaagaaaa cttcaatatc gaggtttgct
     8581 ccctgtgcca cccgttctat accggcaccc aaaaaatcgt cgataccacc ggccgcgtgg
     8641 acaaattcaa caacaaattc ggcaacctgt tcaaacgctg attgccgctt tgcaagaatt
     8701 aagccctgcc atcatttcga tggcagggct ttttaatatt tggcacactg acttcttatc
//
LOCUS       DAXISH010000076         8139 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.076, whole genome shotgun sequence.
ACCESSION   DAXISH010000076 DAXISH010000000
VERSION     DAXISH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8139
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.076"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..101
                     /locus_tag="ACFOV4_001863"
     CDS             <1..101
                     /locus_tag="ACFOV4_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC7619816.1"
                     /translation="KSFPLFLKECEFRFNFGTPSQELKILRDWCGI"
     gene            314..1849
                     /locus_tag="ACFOV4_001864"
     CDS             314..1849
                     /locus_tag="ACFOV4_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HFC7619817.1"
                     /translation="MSDSKTKERATFGTRRAFMIAAIGSAVGLGNIWRFPYIAFENGG
                     GAFILPYLVALLTAGIPLLLLDYAIGHRYRGSAPLAFRRLGRWFEPVGWWNVMTNIVI
                     CIYYAVIIGWAASYTYYSVNAAWGADPQGFFFKDFLQMAGPEALGLDFVGKVAGPLAG
                     VWVFTAAIMALGVQKGVARASSFFMPLLLVMFLIMVGISLTLPGAAKGLDALFTPDWS
                     KLADSKVWVAAYGQIFFSLSICFGIMVTYSSYLKKKTDLGGTGLVVGFANSSFELLAG
                     IGVFAALGFMAQAGGKAVNEVASGGIGLAFIAFPTIINQAPMGWLIGILFFGSLVFAG
                     VTSMISILEVIVAAIQDKLNIGRVNATLLVCIPMGIVSTLLFGTATGLPVLDVMDKFV
                     NTYGIVAAGFVYVAAIIISGRLPELRKHLNALSSIRIGGLWTVCVVVTVVMLGYMLFK
                     DTSGLMEKNYEGYPDGFLSIFGWGMSAALVVFGLLLSLLPWKHGQDFNVKDEHEHEQG
                     EEK"
     gene            1846..1938
                     /locus_tag="ACFOV4_001865"
     CDS             1846..1938
                     /locus_tag="ACFOV4_001865"
                     /inference="COORDINATES: protein motif:HMM:NF033493.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine/alanine import family NSS transporter
                     small subunit"
                     /protein_id="HFC7619818.1"
                     /translation="MSTSAIVMMIVSIVIIWGGLLLSLLRLPNE"
     gene            complement(1974..3218)
                     /gene="lysA"
                     /locus_tag="ACFOV4_001866"
     CDS             complement(1974..3218)
                     /gene="lysA"
                     /locus_tag="ACFOV4_001866"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFC7619819.1"
                     /translation="MTLFCEQVPYPRLAEAFGTPLYVYSQSALTEAFEHYQTAFAELS
                     PLVCYAVKANGNLSIIKHFASLGSGFDIVSGGELARVLAAGGDAAKTIFSGVGKSEAE
                     IEFALNAGVKCFNMESIPEIDRIQKVAARLGKTAPVSLRVNPDVDAKTHPYISTGLKA
                     NKFGIAYADALEAYRHAAQQPNLKIIGIDCHIGSQLTDLSPLVEACERILILVDALAA
                     EGIVLEHLDLGGGVGIVYQNEKVPDLGAYAQAVQKLIGTRRLKLILEPGRSLVGNAGA
                     LLTRVEFVKYGEEKNFVMVDAAMNDLMRPALYDAYHHIEAVEPKNIAPLTANIVGPIC
                     ETGDFLGKDRTIACEEGDLLLIRSAGAYGASMASNYNARNRAAEVLVNGGGYKLIRRR
                     ETLEQQMANELACLQAEHQNAV"
     gene            complement(3229..3399)
                     /locus_tag="ACFOV4_001867"
     CDS             complement(3229..3399)
                     /locus_tag="ACFOV4_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFC7619820.1"
                     /translation="MKYGVFFAAATALLLSACGYKGDLYLPKEGDKARFGVIQTGLQL
                     QGKPQSAPPTQK"
     gene            3470..3793
                     /gene="cyaY"
                     /locus_tag="ACFOV4_001868"
     CDS             3470..3793
                     /gene="cyaY"
                     /locus_tag="ACFOV4_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HFC7619821.1"
                     /translation="MMTESEFIRASEALFEHIEDQIDENGWDFDCRFAGNVLTIEAGD
                     GTQIIVNRHTPNQELWIAAKSGGYHFAEQNGKWLATRDSRDFYDVLNEALSAASGEAV
                     EIEEL"
     gene            3824..4243
                     /locus_tag="ACFOV4_001869"
     CDS             3824..4243
                     /locus_tag="ACFOV4_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2251 domain-containing protein"
                     /protein_id="HFC7619822.1"
                     /translation="MAQLPLYRTAEIGNFTVGTPKVLESFSKHIPYGVVFEDDGDTGY
                     FYAASQDGILDALHIYNVEDVSDKHIPNHVLILWDDACTIAALCVNDYIHAVYDFVEQ
                     AGYCRNGFPEAGGEWVKVENRVLDDELLDKILSREPT"
     gene            4265..4771
                     /gene="luxS"
                     /locus_tag="ACFOV4_001870"
     CDS             4265..4771
                     /gene="luxS"
                     /locus_tag="ACFOV4_001870"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFC7619823.1"
                     /translation="MPLLDSFKVDHTRMHAPAVRVAKTMTTPKGDTITVFDLRFCIPN
                     KEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVAD
                     AWLASMQDVLNVKDQSKIPELNEYQCGTYQMHSLAEAQQIAQNVLARKVAVNKNEELT
                     LDEGLLNA"
     gene            4917..7733
                     /gene="polA"
                     /locus_tag="ACFOV4_001871"
     CDS             4917..7733
                     /gene="polA"
                     /locus_tag="ACFOV4_001871"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFC7619824.1"
                     /translation="MSNRPTLLLVDGSSYLYRAYHAMGQNLTAPDGAPTGALYGVLNM
                     LRRLRSEYPHDYCAVVFDAKGKNFRHQMFEEYKATRPPMPDDLRPQAEALPDLVRLTG
                     WPVLVIGQVEADDVIGTLAKQGAEHGLRVIVSTGDKDMAQLVDERVTLVNTMSSETLD
                     IEGVKAKFGVRPDQIRDYLALMGDKVDNVPGVEKCGPKTAVKWLEAYGSLQGVIEHAS
                     EIKGKVGENLQAALPQLPLSYDLVTIKTDVDLHAELSDGIESLRRTTPKWAQLVVDFK
                     RWGFRTWLKEAESNMNTGSTDDLFGSDSIGEQAALNAEMPFEKQAEKATAPEKLDYQA
                     VTTEAQFAALLDKLSRADTIGIDTETTSLDAMNASLVGISIAFQAGEAVYIPVGHSLT
                     AAPEQLDLQDVLGRLKPHLENPALKKIGQNLKYDQHVFANYGIALNGIAGDAMLASYI
                     IESHLGHGLDELSERWLGLETITYESLCGKGAKQISFADVAIGQATEYAAQDADFALR
                     LEAHLRAQMDAKQLEMYEKMELPVAQVLFEMERNGVQIDRAELARQSAELGAELMKLE
                     QQAYAAAGQPFNLNSPKQLQEILFDKMGIPTKGLKKTAKGGISTNEAVLEQLAPDYPL
                     PKIILQNRSLAKLKSTYTDKLPEMISPWDNRVHTTYAQAVAITGRLASNNPNLQNIPI
                     RTAEGRRVRRAFTAPQGSVIVSADYSQIELRIMAHLSGDKTLIAAFQNGEDVHRRTAA
                     EVFGIAPENVSSEQRRYAKTINFGLIYGMGQYGLAKSLGIDNISAKNFIDRYFARYPG
                     VAEYMQRTKEQAAAQGFVETLFGRRLYLPDIHNKNANARAGAERAAINAPMQGTASDL
                     IKRAMIDVSRWLSECEASPWDELLQSKLIMQVHDELVLEVVETELDFVKEKLPQIMAK
                     VGGGLLDVPLVAEVGVGENWEEAH"
BASE COUNT         1915 a         2165 c         2179 g         1880 t
ORIGIN      
        1 gtaaatcttt cccgctgttc ttgaaagaat gcgaatttcg atttaacttc ggcacaccgt
       61 ctcaagagct taaaatcctg cgggattggt gtgggattta gggctaatct agtacagccc
      121 ctaaaatttt tcgttttcaa gccttcaccg cttgccatca gcgttaaatt tttttacgat
      181 aagcacatag attgtaaaca atcggccaca agccggtttg ttttttcaga agacattatc
      241 cctgtcagac gctatttcta tatatttcgc ctataatggc ttgtttttaa taaataattc
      301 aagaggtatc aacgtgtctg attccaagac gaaagaacgc gccacattcg gcacgcgccg
      361 cgcgtttatg attgccgcca tcgggtccgc cgtcggcttg ggcaatattt ggcgtttccc
      421 ctatattgct tttgaaaacg gcggcggcgc gttcatcctg ccctatctgg tcgcgcttct
      481 gacggcgggc atcccgctgc tgctgctcga ttatgccatc ggccaccgtt accgtggttc
      541 tgcgcccttg gctttccgcc gcctcggacg atggtttgag ccggtcggct ggtggaacgt
      601 gatgaccaat atcgtcatct gcatctatta cgcggtaatt atcggttggg cggcaagcta
      661 tacctattat tcggtcaacg ccgcctgggg tgcggatccg cagggttttt tctttaagga
      721 cttcctgcaa atggcgggcc cggaagcctt gggtttggat tttgtcggca aagtcgccgg
      781 tcctttggcg ggcgtgtggg tttttaccgc cgccattatg gcgttgggcg tgcaaaaggg
      841 cgtggcgcgc gcctcgtcgt tctttatgcc gctgcttttg gtgatgtttt tgattatggt
      901 cggcatttca ctaaccctgc cgggtgcggc aaagggcttg gacgcattgt ttacgcccga
      961 ctggtcgaaa ctcgccgatt ccaaggtctg ggtggcggca tacgggcaga ttttcttttc
     1021 gctttccatc tgcttcggca ttatggttac ctattcttct tatttgaaga aaaaaaccga
     1081 cttgggcgga acggggctgg tggtcggttt tgccaacagc agctttgaac tgctcgcggg
     1141 catcggcgtg tttgccgcat tgggctttat ggcgcaggcg ggcggtaagg cggtcaacga
     1201 ggttgcctca ggcggcatcg gtttggcgtt tatcgccttt ccgaccatta tcaaccaggc
     1261 accgatgggc tggctgatcg gcatattgtt tttcggttcg ctggtattcg ccggcgttac
     1321 gtcgatgatt tccatccttg aagtgattgt ggcggcgatt caggacaagc tgaacatcgg
     1381 gcgcgtcaac gccacgctgc tggtctgcat tccgatgggc attgtttcca cgctgctgtt
     1441 cggtacggcg acggggctgc cggttttgga cgtgatggac aaattcgtca acacctacgg
     1501 cattgttgcc gccggctttg tttatgttgc cgccatcatc atcagcggca ggctgccgga
     1561 attacgcaag cacctgaacg ctttgtcctc catccgcatc ggcggcttgt ggacggtctg
     1621 cgtcgtggtt accgtcgtga tgctcggcta tatgctgttt aaagatacca gcggcctgat
     1681 ggagaaaaat tacgaaggtt atccggatgg tttcctcagt attttcggct gggggatgtc
     1741 ggcggcgttg gtcgtgttcg ggctgctgct gtcgttgctg ccttggaaac acggtcagga
     1801 tttcaacgtc aaagacgaac acgaacatga acaaggagaa gaaaaatgag tacttccgcc
     1861 attgtgatga tgattgtctc aatcgtgata atctggggag ggctgctgct ttccctgtta
     1921 aggctgccga acgagtaagc ctttagagcg ttaaaaatgc cgtctgaacc gcttcagacg
     1981 gcattttgat gttcggcttg caggcaggcg agttcgtttg ccatttgctg ttctaaggtt
     2041 tcgcgtcggc ggatgagttt gtatccgcca ccgttaacca acacttccgc cgcacggttg
     2101 cgcgcgttgt aattgctcgc catactggct ccgtatgcgc ccgcgctgcg gataagcagc
     2161 aaatcgcctt cttcgcaggc gatggtgcgg tctttgccga ggaagtcgcc ggtttcacaa
     2221 atcgggccga cgatgttggc agtcagcggc gcgatgtttt ttggttctac cgcttcgatg
     2281 tgatgatagg catcatatag ggcggggcgc attaaatcgt tcatcgccgc atcgaccatc
     2341 acaaagtttt tctcttcgcc gtatttgacg aattcgacac gcgtcaacaa cgcgcctgcg
     2401 ttgccgacca agctgcggcc gggctcaaga atgagtttca gacggcgtgt gccgatcagt
     2461 ttttgaaccg cttgggcata cgcgcccaaa tcaggcactt tttcgttttg gtaaacaatg
     2521 ccgacgccgc cgcctaagtc caaatgttcc aaaacaatgc cttcggcggc aagcgcgtca
     2581 accaaaatca aaatgcgttc gcaggcttcg accagcgggc ttaagtcggt tagttgggag
     2641 ccgatgtggc agtcgatgcc gatgattttc aaattgggct gttgtgcggc atggcggtag
     2701 gcttcgagcg cgtcggcgta ggcgataccg aatttgttgg ctttcaaacc tgtggagatg
     2761 taaggatggg ttttcgcatc gacatcggga ttgacgcgca gggagacggg cgcggtttta
     2821 cccaaacgcg cggcaacttt ctgaatacgg tcgatttcgg ggatgctttc catattgaag
     2881 catttcacgc ctgcattcag cgcgaactcg atttccgcct cgcttttgcc tacgcctgaa
     2941 aatatggttt ttgccgcgtc gccgcctgcc gccaaaacgc gtgccaattc gccgccggac
     3001 acaatgtcaa aaccgctccc caaagaagca aagtgtttga tgatgctcag gttgccattg
     3061 gctttaaccg catagcagac gagcggggag agctcggcaa aggcagtttg gtagtgttca
     3121 aatgcttcgg tcagcgcgga ttggctgtac acataaagcg gtgtgccgaa tgcttcggca
     3181 aggcgggggt aggggacttg ttcgcaaaat agggtcatat tttcgttttc atttttgggt
     3241 tggaggggcg gattgcggtt tgccttgaag ctgcaaaccg gtttggatta cgccgaaacg
     3301 cgccttgtcg ccttctttgg gcaggtagag gtcgcctttg taaccgcagg ccgagagcag
     3361 gagggcggtt gccgccgcaa aaaatacgcc gtatttcatc ggtaaacttc cttcataagc
     3421 gcgaatgtgg caagattcgg catcttaaac aaaaaacacg caaaaagcta tgatgaccga
     3481 aagcgagttt atccgcgcga gcgaagcatt atttgaacac atcgaagacc aaatcgacga
     3541 aaacggctgg gatttcgact gccggtttgc cggaaacgtc ctgaccatcg aagccggaga
     3601 cggcacgcaa atcatcgtca accgccacac gcccaaccaa gaattgtgga ttgccgcaaa
     3661 aagcggcggc taccatttcg ccgaacaaaa cggcaaatgg ctggcaacgc gcgacagccg
     3721 cgatttttat gatgttttga acgaagcact gagcgcggct tcgggcgaag cggttgagat
     3781 tgaggaattg tgattcaatt tgatataaaa agattgttac ccaatggcac aattacctct
     3841 atatcggact gccgaaatcg gaaattttac tgtcggcacg cctaaagttt tagaatcatt
     3901 ttccaaacat atcccttatg gtgtcgtctt tgaagacgac ggcgacacgg gctacttcta
     3961 tgctgcttcg caagacggga ttttagatgc cttgcacatc tacaatgtcg aagatgtatc
     4021 cgacaaacat atccccaatc atgtcttgat tttatgggat gatgcctgca ccatagccgc
     4081 attgtgtgtc aacgactaca ttcatgccgt ctatgatttt gtcgaacagg caggatattg
     4141 ccgcaacggc ttccctgaag caggcggcga atgggtgaaa gtcgaaaacc gcgtcttgga
     4201 tgatgaattg ctggacaaaa tcctatcccg agaacctaca taaccctcac aaaaggatac
     4261 ccaaatgccc ctactagaca gtttcaaagt cgatcacacc cgtatgcatg cccccgccgt
     4321 acgcgtggcg aaaaccatga ccacgcccaa aggcgacacc attaccgtgt tcgacctgcg
     4381 cttttgcatt cccaacaaag aaatcctgcc tgaaaaaggc atccacacgc tggagcattt
     4441 gttcgcaggt tttatgcgcg accacttgaa cggaaacggc gtggaaatca tcgacatttc
     4501 cccgatgggc tgccgcaccg gtttttatat gagccttatc ggcacgcctt ccgaacagca
     4561 ggtcgccgat gcgtggctgg cttcgatgca ggatgttttg aatgtcaaag accaaagcaa
     4621 aatccccgag ttgaacgaat accaatgcgg cacttatcaa atgcactcgc tcgccgaagc
     4681 gcaacaaatc gcgcaaaacg tgttggcgcg caaagtggcg gtgaacaaaa atgaagagct
     4741 gacgctggat gaagggctgc tgaacgccta atccgccaaa aatgccgtct gaacaagggt
     4801 ttcagacggc atttgccttt tccgttataa tccggggttg tgcgggggcg ggttttaagc
     4861 cggcatcgtc cttccctatt tttttctgtc ccttatcggt tttaagcggg ttttttatgt
     4921 ccaacagacc tacactcctc ctcgttgacg gatcgtccta cctctaccgc gcgtatcatg
     4981 cgatggggca aaacctgacc gcccccgacg gcgcgccgac gggcgcgctg tatggcgtat
     5041 tgaatatgtt gcgccgtttg cggtcggaat atccgcacga ttattgcgcg gtggtttttg
     5101 atgcgaaagg caaaaatttc cgccatcaaa tgtttgaaga atacaaggcg acgcgcccgc
     5161 cgatgcccga cgatttgcgc ccgcaggcgg aagcactgcc ggatttagtg cgcctgacag
     5221 gctggccggt attggtgatt gggcaggtgg aggcggacga tgtgatcggc acgctggcga
     5281 aacagggggc ggaacatggt ttgcgagtca ttgtttcgac cggcgataag gacatggcgc
     5341 agttggtgga tgagcgcgtt acgctggtga acacgatgag cagcgaaacg ctggacattg
     5401 aaggcgtgaa ggcaaaattc ggcgtgcgcc ccgaccaaat ccgcgattat ctcgcgctga
     5461 tgggcgacaa ggtggacaac gtgccgggcg tggaaaaatg cggcccgaaa acggcggtga
     5521 agtggctgga agcctacggc tcgttgcaag gcgtgataga acacgcttcg gaaatcaagg
     5581 gcaaagtggg cgaaaacctg caagccgcgc tgccccaact gccgctgtcg tatgatttgg
     5641 tcacgattaa aaccgatgtg gacttgcacg ccgagctttc agacggcatc gaaagcctgc
     5701 gccgtactac gccgaaatgg gcgcagctgg ttgtcgattt caaacgctgg ggcttccgca
     5761 cctggctgaa agaagcggaa tcaaacatga ataccggctc gaccgatgat ttgttcggca
     5821 gcgacagcat cggcgagcag gcggctttga atgcggaaat gccgtttgaa aaacaagccg
     5881 aaaaagccac cgcccccgaa aaactggatt atcaagccgt taccaccgaa gcgcagtttg
     5941 ccgctttgtt ggacaaactg tcgcgggcgg acacaatcgg catcgatacg gaaaccacgt
     6001 cattagacgc gatgaacgcc tcgctggtcg gcatcagcat cgctttccaa gcaggcgaag
     6061 cggtttacat ccccgtagga cacagcctga ccgccgcgcc cgaacagctt gatttgcaag
     6121 acgtattagg ccgtctgaaa ccgcatttgg aaaaccccgc cctgaagaaa atcgggcaaa
     6181 acctcaaata cgaccaacac gttttcgcta actacggcat cgccctgaac ggcattgccg
     6241 gcgacgctat gctcgcttcc tacatcatcg aaagccatct tggacacggc ttggacgaat
     6301 tgtccgaacg ttggctgggc ttggaaacca ttacctacga atcattgtgc ggtaaaggcg
     6361 cgaagcaaat cagttttgcc gatgtcgcca tcgggcaggc gaccgaatac gccgcccaag
     6421 acgccgattt cgccttgcgc ctcgaagcgc acctgcgcgc gcaaatggac gccaaacagc
     6481 ttgaaatgta tgaaaaaatg gagctgcccg tcgcgcaagt attgtttgaa atggaacgca
     6541 acggtgtgca aatcgaccgc gccgaactcg cccgccaaag cgcggaactc ggcgccgagc
     6601 tgatgaagct cgaacaacaa gcctacgccg ccgcaggcca gccgttcaac ctcaattcgc
     6661 ccaaacagct gcaagaaatc ctgttcgaca aaatgggcat cccgacaaaa gggctgaaaa
     6721 aaactgccaa aggcggcatt tccaccaacg aagccgtgct cgaacagctc gcgcccgact
     6781 accccctgcc caaaatcatc ctgcaaaacc gcagcctggc gaaactcaaa tccacctaca
     6841 ccgacaaact gcccgaaatg atttctccct gggataaccg cgtgcatacc acctacgccc
     6901 aagccgtcgc cattacagga cgcttggcaa gcaacaaccc caacctgcaa aacatcccca
     6961 tccgcaccgc cgaaggccgc cgcgtacgtc gcgcctttac cgcaccgcaa ggcagcgtca
     7021 tcgtttccgc cgactattcc caaatcgagc tgcgcatcat ggcgcacctc tctggcgaca
     7081 aaaccctcat cgctgcgttc caaaacggcg aagacgtaca ccgccgcacc gccgccgaag
     7141 tgttcggcat cgcccccgaa aacgtctcgt ccgaacaacg ccgctacgcc aaaaccatca
     7201 acttcggcct catttacggc atgggccaat acggcctcgc caaatcattg ggcatcgaca
     7261 acatctccgc caaaaacttt atcgaccgct acttcgcccg ctatcccggc gtcgccgaat
     7321 acatgcagcg caccaaagaa caagccgccg cacaaggctt tgtcgaaacc ctgttcggca
     7381 gaaggctcta cctgcccgac atccacaaca aaaacgccaa cgcccgcgcc ggagccgaac
     7441 gcgccgccat caacgccccc atgcaaggca ccgcctccga cctcatcaaa cgcgccatga
     7501 tagacgtgtc ccgctggctt tcagagtgcg aagcctcccc gtgggacgaa ctcttacaaa
     7561 gcaaactgat tatgcaggtg catgacgaac tggtgctgga agtcgttgaa accgaactgg
     7621 attttgtcaa agaaaaactg ccgcagatta tggcgaaagt gggcggcgga ttattggatg
     7681 taccgctggt ggctgaggtt ggcgtagggg agaattggga agaggcacat tgattgaaag
     7741 gtgttatatg ctatctttat ttaaataaaa tttaattttt ggtatatttt ttctaaatgt
     7801 tcctatagta tagtggatca acaaaaatca ggacaaggcg acgaagccgc agacagtaca
     7861 aatagtacgg aaccgattca cttggtgctt cagcacctta gagaatcgtt ctctttgagc
     7921 taaggcgagg caacgccgta ctggtttttg ttaatccact atattccgcc atctctaaga
     7981 tttacagcga tacacgggtg atttaaggaa tgcccgaacc gtcattcccg caacttttcg
     8041 tcattcccac gaaagtggga atctagaaat aaaaagcagc aggaatttat cggaaataac
     8101 tgaaaccgaa cagactagat tcccgcctgc gtgggaatg
//
LOCUS       DAXISH010000077         8038 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.077, whole genome shotgun sequence.
ACCESSION   DAXISH010000077 DAXISH010000000
VERSION     DAXISH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8038
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.077"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            444..1757
                     /locus_tag="ACFOV4_001872"
     CDS             444..1757
                     /locus_tag="ACFOV4_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HFC7619825.1"
                     /translation="MLTFIGLLIIGVIVWLLLTEKVSPIIALILMPLFGALLAGFDVS
                     QLKEFYSGGTKSVMQIVIMFMFSILFFGIMNDVGLFRPMIGGLIKLTRGNIVAVSVGT
                     VLVSVVAQLDGAGATTFLLVVPALLPLYKRLHMNPYLLFLLLTSSAGLINLLPWGGPT
                     GRVASVLGADVGELYKPLLTVQIIGVVFILALSLLLGVREKRRIVRELGALPAVADLI
                     KPVPLSEEEQKLARPKLFWWNVLLFLAAMSLLFSGIFPPGYVFMLAATAALLLNYRSP
                     QEQMERIYAHAGGAVMMASIILAAGTFLGILKGAGMLDAISKDIVHILPDALLPYLHI
                     AIGVLGIPLELVLSTDAYYFGLFPIVEQITSQAGVAPEAAGYAMLIGSIVGTFVTPLS
                     PALWMGLGLAKLSMGKHIRYSFFWAWGLSLAILASSIAAGIVPLP"
     gene            1978..2135
                     /locus_tag="ACFOV4_001873"
                     /pseudo
     CDS             1978..2135
                     /locus_tag="ACFOV4_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003824008.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            2148..3398
                     /locus_tag="ACFOV4_001874"
     CDS             2148..3398
                     /locus_tag="ACFOV4_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFC7619826.1"
                     /translation="MFVPLAMLAGMFSYYETFHETEALQDDLLRQAALYVAPDSKPET
                     LPEGDGDTRILVQMPQQEDPVVSLPAHLADGLHTLQADGDDDYYRVYIRTTERGRIAV
                     MQESEYREDLAADAARQSVLPLLAALPLMILLTVWITHKAMRPVRKLSQSLEQRRIND
                     LSALSVDNIPSEIRGFVTAINLLLKRADEDIRHRQRFVADAAHELRTPMTALSLQAER
                     LNNMSLPPDAARQSAVLQQSIRRNKHLLEQLLALARSQSDETPLAKTTFGLQSRFRQV
                     LQELMPLALEKRQDIGVAVGGDVEIFADETEIYTLVKTFVDNAIRYTPSEGRIDLGFT
                     DEGKYLAVWVEDNGNGIPESERVRVLDPFYRILGTEQQGTGLGLSIADTLAKKYGGYL
                     ELTDSRRFGHGLLIRALLDKETLK"
     gene            complement(3433..4926)
                     /gene="rng"
                     /locus_tag="ACFOV4_001875"
     CDS             complement(3433..4926)
                     /gene="rng"
                     /locus_tag="ACFOV4_001875"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HFC7619827.1"
                     /translation="MLSGLPIPKDIARPPETILVNITPQETRVAVLEENNICELHIER
                     NSEHSLVGNIYLGVVRRVLPGMQSAFIDIGLERAAFLHIVDVLEQRRNPEETQRIEHM
                     LFEGQSVLVQVIKDPINTKGARLSTQISLAGRFLVHLPQEDHIGVSQRIEDDAERSSL
                     RERLDKLLPENACRGYIIRTNAENATDEQLQSDIDYLTKVWEHIQEQAKIRPPETLLY
                     QDLPLSLRVLRDMVGCDTQKILVDSTVNHGRMTRFAEQYVHGALGRIELFKGERPLFE
                     THNVEQEISRALQPRVNLNFGSYLIIESTEAMTTIDVNTGGFVGARNFDETIFRTNLE
                     ACHTIARELRLRNLGGIIIIDFIDMAQESHREAVLQELAKALAFDRTRVTLHGFTSLG
                     LVELTRKRSRENLNQVLCEPCPSCQGRGRLKTPQTVCYEIQREIVREARRYDAESFRI
                     LAASNVIDLFLDEESQSLAMLIDFIGKPISLAVETAYTQEQYDIVLM"
     gene            5139..5396
                     /gene="grxC"
                     /locus_tag="ACFOV4_001876"
     CDS             5139..5396
                     /gene="grxC"
                     /locus_tag="ACFOV4_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HFC7619828.1"
                     /translation="MQTVTMYTGPFCPYCAMAKRLLHAAGVGHIDEIRVDASPEAFAE
                     MQQLSGQRSVPQIFIGETHVGGFTDLYRLQQEGGLDGLLNP"
     gene            5417..5860
                     /gene="secB"
                     /locus_tag="ACFOV4_001877"
     CDS             5417..5860
                     /gene="secB"
                     /locus_tag="ACFOV4_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HFC7619829.1"
                     /translation="MSEELQPVFSIERLYVKDLSLEVPHAPQIFLEQGEPEVDMRVST
                     GSQKLEDGYYNVDVTVTVTAKLDNERTMFLNEVTQSGIFRLENIPEEDVQLLLGVACP
                     NILFPYAREAVSSTVTRAGFPPVLLAPINFEAIYQQQQEAEAAGA"
     gene            5946..7988
                     /gene="recG"
                     /locus_tag="ACFOV4_001878"
     CDS             5946..7988
                     /gene="recG"
                     /locus_tag="ACFOV4_001878"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFC7619830.1"
                     /translation="MMSPETQKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETH
                     IMPIKDAPIGVPCQVEGEVIHQEVTFKPRKQLIVQIADGSGSVLFLRFIHFYASHQKQ
                     TAVGKRIRAVGEIKHGFYGDEMIHPKIRDAEGGGLAESLTPVYPTVNGLNQPTLRRII
                     QTALDVTPLHDTLPDALLCRLKLQHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKF
                     DELLAQQLSMRLARQKRVSGTAAALGGDGTLTQALRHALPFALTDAQEKVVSEICRDM
                     AQTHPMHRLLQGDVGSGKTIVAALSALTAIESGAQVAVMAPTEILAEQHFIKFKQWLE
                     PLGLEVVWLSGSQRKKAKDEAKAKLADGTVKIAVGTHALFSDDVEFQNLGLVIVDEQH
                     RFGVAQRLALKNKGRDVHQLMMSATPIPRTLAMSFFADLDVSVIDELPPGRTPIKTRL
                     VNNVRRAEVEGFVLGTCRKGRQAYWVCPLIEESETLQLQTAAETLARLQTALPELNIG
                     LVHGRMKAAEKAEVMARFSSGELNVLVATTVIEVGVDVPNAALMVIEHAERMGLAQLH
                     QLRGRVGRGAAESVCVLLFAEPLGELAKARLKVIYEHTDGFEIARQDLNIRGPGEFLG
                     ARQSGVPMLRFAKLEEDLHLLEQAREIAPILIEQNPEIVEAHLARWLSGREGYLGV"
BASE COUNT         1698 a         2080 c         2367 g         1893 t
ORIGIN      
        1 ttaacaaaaa ccagtacggc gttgcctcgc cttagctcaa agagaacgat tctctaaggt
       61 gctgaagcac caagtgaatc ggttccgtac tatttgtact gtctgcggct tgccgccttg
      121 tcctgatttt tgttaatcca ctataaaatc ccacgtgtac ggcacgcccc gcgctccgca
      181 atgatagggg cggtttcgtt tgaatcggcg taccgggatg aatgcccccg cgccgtcccg
      241 ataccggttt gccggttgtt ccgtatcggt tgccgccgtg aaatgacgga cggatacagg
      301 aatggcggca ggcgtaaatg ggaggaaatg accgattgac ttgtttcaaa ataaaaaagt
      361 agaatgcaag gcttatcccg cgtctgtggg cggttttgcc tgcacggtcg gttttctgtt
      421 taaaataaaa taaaggagaa atgatgctga cgtttatcgg actgctgatt atcggggtca
      481 tcgtatggtt gctgctgacg gaaaaagtgt cgcccatcat cgcattaatc ttgatgccgc
      541 tgtttggggc gttgctggcg gggtttgatg tatcccaatt aaaagaattt tattcgggcg
      601 gcaccaaatc ggtgatgcag attgtgatta tgtttatgtt ttccattttg ttttttggaa
      661 tcatgaacga tgtggggctg ttccgtccga tgataggcgg tttgattaag ctgactcggg
      721 gtaatatcgt ggcagtgagt gtggggacgg tcttggtgtc ggtggtggcg cagttggacg
      781 gggcgggtgc gacgacgttt ttattggtcg tccccgccct tttgccgctt tacaagcgtc
      841 tgcatatgaa tccttacctg ctgtttttgc tgctgacttc cagtgcggga ttgattaacc
      901 ttctgccgtg gggcgggccg actgggcggg ttgcaagcgt gttgggcgca gatgtgggcg
      961 aattgtataa acctttgttg acggtgcaaa ttatcggtgt agtgtttatc cttgcgctgt
     1021 ccctgctttt gggtgtgcgt gaaaaaaggc ggattgtccg ggagttgggc gcgttgcccg
     1081 ccgtggcgga tttgataaag ccggtgcctt tgtcggaaga agaacaaaaa ttggcgcgtc
     1141 cgaaactgtt ttggtggaat gtcctgctgt ttttggcggc gatgagcctg cttttttcgg
     1201 gcatcttccc gccgggttat gtatttatgc tggctgcaac ggcggcgttg cttttgaatt
     1261 accgcagccc gcaggaacag atggagcgga tttatgccca cgccggcggc gcggtgatga
     1321 tggcgtccat tattttggcg gcaggtacgt ttttggggat tttgaagggt gcggggatgt
     1381 tggacgcgat ttccaaagac attgtgcata tcctgccgga cgcgctgctg ccttatctgc
     1441 atattgccat cggtgtgttg ggcattccgc ttgagttggt tttgagtacg gacgcttatt
     1501 atttcggact gtttccgatt gtggagcaga ttacctcgca ggcgggcgtg gcgcccgaag
     1561 cagcaggtta tgcgatgttg atcggcagta tcgtcggcac ttttgttacg ccgctttcgc
     1621 cggctttgtg gatgggcttg ggtttggcga aattgtcgat gggcaaacac atccgttatt
     1681 cgtttttttg ggcgtggggt ttgtcgctgg cgatattggc cagttcgata gcggcaggaa
     1741 tcgtgcctct gccgtaaacg gcgaagccgt ctgaagcccg aatcgttcct gtggtctgtc
     1801 gcaggctgcc tgcctgcccg tgtgttgcaa tcgcgcccca atgccgtctg aaggcagttg
     1861 ccggcgcggt ttttttgtgc tgcagttttg aaaaataccg gcaagcgtaa aggccgctaa
     1921 attgcggcta attttggggt gttagaatag gcacggtttg tctgaaaggg aaagttgatg
     1981 cgtgttttgc tggtggaaga cgatgcgatg attgcggagg cggtgtcggc aagtttgaaa
     2041 gacggcggct atgcggtgga ttgggtcaaa aacggcgcgc ggctgccgct gcccagcctt
     2101 atgacttgat gctgctggat ttgggtttgc cggggcggac ggtttggatg tttgttccgc
     2161 tggcaatgct tgcaggtatg ttttcctact acgaaacctt ccacgaaacg gaagcgttgc
     2221 aggacgacct gctccgtcag gcggcattgt acgtcgcccc cgattccaaa cccgaaactt
     2281 tgcccgaggg cgacggcgat acgcgtattt tggtacagat gccgcagcag gaagaccctg
     2341 ttgtcagcct gcctgcgcat ctggcggacg gtctgcacac gcttcaggcg gacggggacg
     2401 acgattatta ccgcgtctat atccgcacga cggagcgggg gcggattgcc gtgatgcagg
     2461 aaagcgaata ccgggaagat ttggcggcgg atgcggcacg gcaaagcgtg ttgcccctgc
     2521 tggcggcact gccgctgatg atactgctga ccgtgtggat tacgcacaaa gccatgcgcc
     2581 ccgtccgcaa attgtcgcaa agtctcgaac aacgccgaat caatgacctg tctgccttga
     2641 gtgtggacaa tattcccagt gaaatcagag ggttcgtaac cgccatcaac ttgcttttga
     2701 aacgtgcgga tgaagacatc cgccaccgtc agcggtttgt cgccgacgcg gcacacgaat
     2761 tgcgtacgcc gatgacagcc ctttcccttc aggcggaacg gctcaacaat atgtctctgc
     2821 cacccgatgc ggcgcggcag tctgccgttt tgcagcaaag catacggcgc aacaaacacc
     2881 tgctcgagca gcttttggca ctggcgcgtt cgcagtcgga cgaaacccct ttggcgaaaa
     2941 cgacattcgg tctgcaaagc cgtttccgcc aagtgttgca ggaactgatg ccgcttgcct
     3001 tggaaaaacg tcaggacatt ggtgtggcgg tcggaggtga tgtcgaaata tttgccgatg
     3061 aaactgaaat ctataccttg gttaaaacgt ttgttgataa cgcaatacgt tataccccgt
     3121 ccgaaggcag gatagatttg ggtttcacag acgaagggaa atatcttgcc gtgtgggtgg
     3181 aagataacgg gaacggcatt ccggaatccg aacgcgtccg cgtcctcgat ccgttttacc
     3241 gtattttggg aacggagcag caggggacgg ggctggggct gtcgattgcc gacacgctag
     3301 ccaaaaaata cggcggatat ttggaactga ccgacagccg caggttcgga cacggtctgc
     3361 tgatacgcgc cttgttggac aaggaaaccc tgaaatagac agatgccgtc tgaaggcttc
     3421 agacggcatt ttttacatca gcacaatatc gtattgttcc tgcgtgtaag cggtttcgac
     3481 cgccagagaa atcggtttgc cgatgaaatc tatcagcatt gccaaggatt gcgattcttc
     3541 gtccaaaaac aaatcgatga cgttggaggc ggcgaggatg cggaaacttt cggcatcgta
     3601 acggcgcgct tcgcggacga tttcgcgctg gatttcgtag cacacggttt gcggcgtttt
     3661 cagacggcct ctgccttggc aggaagggca gggttcgcag aggacttggt ttaagttttc
     3721 gcgcgagcgt ttgcgcgtca gctcgaccag ccccaggctg gtaaaaccgt gcagggtaac
     3781 gcgggtacgg tcgaaggcga gggctttggc aagctcctgc aacacggctt cgcggtggct
     3841 ttcctgcgcc atatcgatga agtcgatgat gatgatgccg ccgaggttgc gtagcctcaa
     3901 ttcgcgggcg atggtgtggc aggcttcgag gttggtgcgg aagatggttt cgtcgaagtt
     3961 gcgtgcgccg acgaagccgc cggtgttcac gtctatcgtg gtcatcgctt cggtggactc
     4021 gataatcagg tagctgccga agttgaggtt gacgcgcggt tgcagggcgc ggctgatttc
     4081 ctgctcgacg ttgtgggttt caaacagcgg gcgttcgcct ttgaacaatt ctatcctgcc
     4141 caatgcgccg tggacgtatt gttcggcaaa acgcgtcatc cgtccgtggt ttacggtgga
     4201 atcgacgagg attttttgcg tgtcgcagcc gaccatatcg cgcaatacgc gcaaactcaa
     4261 gggcaaatcc tgataaagca gggtttccgg cggccggatt ttcgcctgtt cttggatgtg
     4321 ttcccacact ttggtcaggt agtcgatgtc ggactggagc tgttcgtcgg tggcgttttc
     4381 ggcgttggtg cggatgatgt agcctcggca ggcattttcc ggcaggagct tgtcgaggcg
     4441 ttcgcgcagg ctgctgcgtt cggcatcgtc ttcgatgcgt tgggacacgc cgatgtggtc
     4501 ttcttgcgga agatggacga ggaaacgccc cgccagcgag atttgggtgg aaagccgcgc
     4561 gcctttggtg ttgatcgggt ctttgatgac ctgcaccaaa acagactgcc cttcaaacag
     4621 catatgttcg atgcgctggg tttcttcggg gttgcggcgt tgttcgagga catcgacgat
     4681 gtgtaaaaac gccgcgcgtt ccaagccgat gtcgataaac gcgctctgca tcccgggcag
     4741 cacgcggcgc accacgccca gatagatatt gccgaccagg ctgtgttcgc tgttgcgctc
     4801 gatgtgcagc tcgcagatat tgttttcctc caacaccgct acgcgcgttt cctgcggcgt
     4861 gatgttgacc aatatcgttt cgggcgggcg cgcgatgtct ttggggatgg ggagtcctga
     4921 caacatggtt tttcctgaaa atgtaataaa aatattttgc atccgttccg ccgcgcagcg
     4981 cgggtgcaaa aatatttttc acaatgtcta tcatacttta aaaaagaaac tttgacacat
     5041 tccgcacatg ccgtttgaac gtgcatctgt tccgcacttg ccaaacaggg gaaatgcccc
     5101 tatattgatt atcattgcaa aactttcgga aacccaatat gcagaccgtt accatgtaca
     5161 caggtccgtt ttgtccctac tgcgcgatgg cgaaaaggct gctgcacgcg gcaggtgtcg
     5221 gacatatcga cgaaatccgt gtcgatgcaa gccccgaagc ctttgccgaa atgcagcagc
     5281 tttcgggaca gcgcagcgtg ccgcagattt tcatcggcga aacgcacgtc ggcggattta
     5341 ccgacctcta ccgcctccag caggaaggcg ggctggacgg actgctgaac ccttaacccc
     5401 caactaggaa aacaaaatga gcgaagaact gcaacccgta ttcagcatcg agcgactgta
     5461 tgtcaaagac ttgtctttgg aagtgccgca cgcgccgcaa atctttttgg aacagggcga
     5521 gcccgaagtg gatatgcgcg tttccaccgg cagccaaaag ctggaagacg gctactacaa
     5581 cgtggatgta accgttaccg taaccgccaa attggataac gagcgcacga tgtttttgaa
     5641 cgaagtaacc caaagcggca tcttccgttt ggaaaacatc cccgaagaag atgtgcagct
     5701 gctgctgggc gtggcgtgtc cgaacatcct cttcccttac gcgcgcgaag ccgtttccag
     5761 tacggtaacg cgcgccggct tcccgcccgt cctgctcgcg ccgattaatt ttgaggcgat
     5821 ttaccaacaa cagcaggaag ccgaagccgc cggggcttga ttcctgcctg ccgatgccgt
     5881 ctgaatccgt ttcagacggt atttttgttt tcggataaaa taggtgcgtt caaaggaatc
     5941 tgcctatgat gtcgcccgaa acccagaaac agctcaaaat caccgatgtt tccgccaaga
     6001 agctcgacaa actcaacctc cataccgcgt gggatttggt gttgcacctg ccgctgcgtt
     6061 acgaggacga gacgcacatt atgccgatta aggacgcgcc gattggcgtg ccgtgccagg
     6121 tcgagggcga ggttatccat caggaagtaa cgttcaaacc gcgcaagcag ttgattgtcc
     6181 aaatcgccga cggttccggc agcgtccttt ttctgcgctt catccacttt tacgccagcc
     6241 atcagaaaca gacggcggtc ggcaaacgca tccgcgccgt gggcgaaatc aaacacggct
     6301 tttacggcga cgagatgatt catcccaaaa tccgcgatgc cgagggcggc ggtttggcgg
     6361 aaagcctcac gccggtttac ccgaccgtaa acggtttgaa ccagcccact ttgcgccgta
     6421 ttattcagac ggcgttggac gttacgccgc tgcacgacac gctgcccgat gccctgctgt
     6481 gccgtctgaa gctgcaacac ctcgccgaaa gcctgcgtct tttgcattcg ccgccgccga
     6541 gtttcacgat tcatcagctt tcagacggca cgctgcctgc atggcaacgg ctcaaattcg
     6601 acgaactttt ggcgcaacag ttgtccatgc ggctggcgag acagaagcgc gtcagcggca
     6661 cggcggcggc attgggcggc gacggtacat tgacgcaagc cctgcgccac gccttaccgt
     6721 ttgccctgac tgatgcacaa gaaaaagttg tttccgaaat ctgccgcgac atggcgcaaa
     6781 cccaccccat gcaccgcctg ctgcaaggcg atgtcggcag cggcaaaacc atcgtcgccg
     6841 ccttgtctgc tttgacggct attgaatccg gcgcacaggt ggctgtaatg gcgccgaccg
     6901 aaatccttgc cgaacagcac ttcatcaagt tcaaacaatg gcttgagccg ttgggtctcg
     6961 aagttgtttg gctttccggc agtcagcgca aaaaagccaa ggatgaagcc aaagccaaac
     7021 tggctgacgg caccgtcaaa atcgccgtcg gcacgcatgc cctgttttca gacgacgtcg
     7081 agttccaaaa tttgggcttg gtgattgtgg acgaacaaca ccgcttcggt gtcgctcaac
     7141 gccttgccct caaaaacaaa gggcgcgacg tccatcaatt gatgatgtcc gccacgccca
     7201 tcccgcgcac gcttgcgatg agttttttcg ccgatttgga cgtgtccgtc atcgacgaat
     7261 tgccgcccgg gcgcacaccg attaaaacgc gcctcgtcaa caacgtccgc cgcgccgaag
     7321 tcgaaggctt cgtcctcggc acttgccgaa aagggcggca ggcgtattgg gtctgcccat
     7381 tgattgaaga aagcgaaacc ctgcaactgc aaaccgccgc cgaaaccctc gcccggcttc
     7441 agacggcatt gcccgaactc aatatcggac tggtacacgg gcgcatgaag gccgccgaaa
     7501 aggccgaagt gatggcgcgg ttttcttcgg gggagctgaa tgtcttggtc gccaccaccg
     7561 tcatcgaagt cggcgtagat gtgcccaacg ccgccctgat ggtcatcgaa cacgccgagc
     7621 gcatgggctt ggcgcagctg caccaattac gcggacgggt agggcgcggc gcggcagaaa
     7681 gcgtgtgcgt cctcctgttt gccgaaccct tgggcgaact cgccaaagcg cggttgaaag
     7741 tgatttacga acacaccgac ggctttgaaa tcgcccgcca agacctcaac atccgcggcc
     7801 ccggcgaatt tctcggcgcg cgccaaagcg gcgtgcctat gctgcgtttc gccaagctcg
     7861 aagaagactt acaccttttg gaacaagcgc gcgaaatcgc cccgatactg attgagcaaa
     7921 accccgaaat cgtcgaagcg catttggcaa gatggctttc cggcagggaa gggtatttgg
     7981 gcgtgtgagc aaaatgccgt ctgaaatatt agaaaaaaaa gtgtaacgga aatctgat
//
LOCUS       DAXISH010000078         7893 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.078, whole genome shotgun sequence.
ACCESSION   DAXISH010000078 DAXISH010000000
VERSION     DAXISH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.078"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            117..593
                     /locus_tag="ACFOV4_001879"
     CDS             117..593
                     /locus_tag="ACFOV4_001879"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008813 - chorismate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HFC7619831.1"
                     /translation="MGYGFEEWLPDLPAPVSDGIGLPMSRLLKARSLTAALRALPHTF
                     SVELLKLGELETECGGRLVREVLLKLDGIPVVAARSECRIGSAFWQNILDCGTRPLGE
                     RLFQADLEGARSAFEFAVSGEGCGRYFAARRSRFSRHGEEMLLTEYFLPELKRFIG"
     gene            623..1513
                     /gene="ubiA"
                     /locus_tag="ACFOV4_001880"
     CDS             623..1513
                     /gene="ubiA"
                     /locus_tag="ACFOV4_001880"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008412 - 4-hydroxybenzoate
                     octaprenyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HFC7619832.1"
                     /translation="MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLA
                     SDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFDGAVERTKNRPFAQGRVGKKEAL
                     LLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIP
                     MAFAAVAGNVPPQAWILFAANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIA
                     AVMLCHGGFTLLMAVLGAVIGAAWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLA
                     NNRIGWVWFTAIFAHTFFAK"
     gene            1698..2147
                     /gene="ptsN"
                     /locus_tag="ACFOV4_001881"
     CDS             1698..2147
                     /gene="ptsN"
                     /locus_tag="ACFOV4_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HFC7619833.1"
                     /translation="MSLIGEILPLSHIVLDMEVGSKKRLFEEAGLLLERESSLSHADV
                     FECLFAREKLGSTGLGQGVAIPHGRHAGVKQATGAFIRTREPVGFDAPDGKPVSLIFI
                     LLVPENATGEHLEVLSKLAGKFSQKSIRESLMTVSSAEEARAILTEE"
     gene            2149..3111
                     /gene="hprK"
                     /locus_tag="ACFOV4_001882"
     CDS             2149..3111
                     /gene="hprK"
                     /locus_tag="ACFOV4_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFC7619834.1"
                     /translation="MPSISVRRLFDDNQYKLQLAWAAGNSGADNRIGVEADKPVLALV
                     GHLNFIHPNQIQVVGLAESEYLNRLESGETGYQFGDLFDISMSLVIVANGLPVSPGLR
                     DYCHKNDIPLLTSKLESPYLMDVLRIYLQRTLAASSVKHGVFLDVFEIGVLITGHSGL
                     GKSELALELISRGHSLIADDAVELFRIGPETLEGRCSPMLRDFLEVRGLGILNIRHIF
                     GETSIRPKKILQLIINLVEADDEYMKQLDRLSIRTETESILNVNVRSVTLPVAVGRNL
                     AVLVEAAVRNYILQLRGKDSTREFLERHQTQLKENEQNHENRPD"
     gene            3092..3946
                     /gene="rapZ"
                     /locus_tag="ACFOV4_001883"
     CDS             3092..3946
                     /gene="rapZ"
                     /locus_tag="ACFOV4_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFC7619835.1"
                     /translation="MKIVLISGLSGSGKSVALRQMEDSGYFCVDNLPLEMLPALVSYH
                     IERADETELAVSVDVRSGIDIGQAREQIASLRGLGHRVEVLFVEAEESVLVRRFSETR
                     RGHPLSNQDMTLLESLKKEREWLFPLKEIAYCIDTSKMNAQQLRHAVRQWLKVERTGL
                     LVILESFGFKYGVPNNADFMFDMRSLPNPYYDPELRPYTGMDKPVWDYLDGQPLVQEM
                     VDDIERFVTHWLPRLEDESRSYVTVAIGCTGGQHRSVYIVEKLARRLKGRYELLIRHR
                     QAQNLPSR"
     gene            4027..4968
                     /gene="ylqF"
                     /locus_tag="ACFOV4_001884"
     CDS             4027..4968
                     /gene="ylqF"
                     /locus_tag="ACFOV4_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFC7619836.1"
                     /translation="MAIQWFPGHMNKAKKAIAERAKSVDMVIEMLDARMPASSENPLL
                     AQLSKGKPKLKILNKQDLADPERTKVWLDHYNSRPDTCAIALDSSETGAHGKITQACR
                     AMIPHRQGIDKPLRVLICGIPNVGKSTLINGMIGKKSAKTGNEPGITKAEQRLFLADD
                     FWLYDTPGMLWPKIIVEESGYNLAAGGAVGRNALDEEEVALELLDYLRRHYLPMLQER
                     YQADKDPSSHWDENVWLEWIAKKRGAVLSGGRINYQKAAENILTDFREGKIGRITLET
                     PNQWETWLKKARQKEAELKAIREARKAERKGKKPSEA"
     gene            5069..5671
                     /locus_tag="ACFOV4_001885"
     CDS             5069..5671
                     /locus_tag="ACFOV4_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFC7619837.1"
                     /translation="MTDKISPDALIEAALLTQTEPLTEKSMRELCVPPLSQDKLIDVL
                     AQLKTRWQDRALQLVHTQEGWRFQIVQTAFERLGSLQEQRAPRYSRAVMETLAIIAYQ
                     QPVTRGDIEGIRGVAVSQNVMQTLQDRGWIEVIGHRDTLGKPALWATTATFLSDLRLD
                     GLEELPPLTELGELVLPDLMEMPPTDEEEPEAVPSDTLPN"
     gene            5855..7528
                     /gene="recN"
                     /locus_tag="ACFOV4_001886"
     CDS             5855..7528
                     /gene="recN"
                     /locus_tag="ACFOV4_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFC7619838.1"
                     /translation="MLLTLSLRDFVIVENLNLDFQSGFTVLTGETGAGKSITLDAIGL
                     LLGDKADYSQVRSGAKEAQLSALFDISHLPVLKAELYEQGLLNDGEEELSIRRIIDAK
                     GKSRSFINNQAATLAQLKAVGSQLIDIHGQNAHHSLNQEAAQRELLDAFAGSRAQAET
                     VRQLYQNWANSKKALQEAQEQAENIALEQERLEWQFNELNQLDIKQGEWEALSQSHDS
                     LAHSAELLQAAEEVGSKIDGDNGIQRHIYQCQKLLANLQNIEPRFAESLNMLASIEAE
                     LGEISANMRDVAGRSDINPNELAAQEQRMGELMGMARKYRIEPEELPAKLAEIEERLQ
                     SLQAAADLDALEHNVAHNFAEYQEAAHILSAMRHQAAERLSGETTEHMQHLAMKGARF
                     DIVLLPSSPTAHGLEQVQFQVAANKGNPPRPLNKVASGGELARISLALQVVASQYTQV
                     PTLIFDEVDTGIGGGVAEMVGKALRALGRKHQVLAVTHLPQVASCGENHWRVRKHSEG
                     EQTVSEISILDEIQRVEEVARMLGGEVITDTTRQHAAELLQLASKNSLF"
     gene            7638..7714
                     /locus_tag="ACFOV4_001887"
     tRNA            7638..7714
                     /locus_tag="ACFOV4_001887"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7672..7674,aa:Arg,seq:acg)
     gene            7732..7806
                     /locus_tag="ACFOV4_001888"
     tRNA            7732..7806
                     /locus_tag="ACFOV4_001888"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7765..7767,aa:Glu,seq:ttc)
BASE COUNT         1969 a         2029 c         2082 g         1813 t
ORIGIN      
        1 ataaaaaaat attatgataa taaatacaat gataatgcag tcaaatcgac aaattgtatt
       61 ggggataatg caagatgtat gcttaataat aaaggatatt caacaaaatg gtaataatgg
      121 gttacggctt tgaggaatgg ctgcccgacc tgcccgcccc tgtttcagac ggcatcggcc
      181 tgccgatgag ccggttattg aaagcccggt cgctgaccgc cgcattgcgc gccttgccgc
      241 atacattttc ggtggaactg ctgaaactgg gcgaattgga gacggaatgc ggagggaggc
      301 tggtgcgcga agttttgttg aagctggacg gtatccctgt tgtcgcggca aggagcgagt
      361 gccgtatcgg ttcggcgttt tggcaaaaca ttttggactg cggcacgcgt cctttgggcg
      421 agcgtctgtt tcaagccgat ttggaagggg cgcgttcggc gtttgagttt gccgtttccg
      481 gcgaaggatg cggacggtac tttgccgcgc ggcgttctcg gttttcccgt cacggcgagg
      541 aaatgctgct gaccgagtat tttctgcccg aactgaaacg ctttatcgga taaaataccg
      601 ttttttcaag ctgtgcggca atatgaatcc taaatcccct ttatttttac gactgtccga
      661 tcgtttggat gtgtacctgc gcctgatgcg ggcggacaag cccattggga cgctgctttt
      721 gctgtggccg acctactggg cattgtggct ggcttcagac ggcattcccg atttggcggt
      781 attggcggcg tttacaatcg gcacgttttt aatgcggagt gccggttgcg tcatcaacga
      841 ttttgccgac cgcgattttg acggtgctgt cgagcgcacc aaaaaccgtc cgttcgcaca
      901 gggtcgggtc ggaaaaaaag aagcgctgct gctgacggca tttttgtgcc tgcttgccgc
      961 attgtgcctg attccgctga atcatctgac atggctgatg agcctgcccg cgctgtttct
     1021 tgcgctgact tacccgttta ccaaacgctt ttttccgatt ccccaactct atctcgggct
     1081 tgccttttcc ttcggtatcc cgatggcgtt tgccgccgtt gccggaaacg tgccgcctca
     1141 agcgtggata ctctttgccg ccaatgtgtt atggactctg gcgtatgaca cggtttatgc
     1201 aatggcggac aaagaagacg atttgaaaat cggcatcaaa acctccgccg tcacgttcgg
     1261 gcgttacgac atcgccgccg ttatgctgtg tcatggcggc tttaccctgc tgatggcagt
     1321 attgggtgcg gttatcggtg cggcatgggc atattggacg gcaatcccca tcgtcctgct
     1381 gctgcaatac cgccaatatg ccgccatcaa aagccgcgtc cggcaaatct gttttgaaac
     1441 gtttttggca aacaacagaa ttggttgggt gtggtttacc gccatttttg cccatacgtt
     1501 tttcgcgaaa taaggcaggg caatgccgtc tgaagagccg taaactgctt tggacggcat
     1561 ttctatctgt gccgaaaagc gttaaaatat gtttttaaaa cgctgtgtta tgtcagcccg
     1621 taccgtatgc gggattgaga tttgccctag cagtcggtac aatctttctg ttttgcgatg
     1681 tctgaaaaga gaagcttatg agccttatcg gcgaaatttt gcctttgtcc catattgttt
     1741 tggatatgga ggtgggcagt aaaaaaaggc tgtttgagga agcgggcctg cttttggaac
     1801 gcgaatcctc attgtcccat gctgatgttt tcgaatgtct ttttgcccgt gaaaaactcg
     1861 gttcgaccgg tttggggcag ggcgttgcca tcccgcacgg ccgtcatgcc ggcgtgaagc
     1921 aggcgacggg cgcgttcatc cgcacgcgcg aacccgtcgg atttgacgca ccggacggca
     1981 agccggtttc cctgattttt atcttgctgg tgccggaaaa cgcaactggc gaacatttgg
     2041 aagtcttatc caaactggcc ggcaagtttt cccaaaaaag catccgcgaa tcgctgatga
     2101 cggtttcttc tgcggaagaa gcccgcgcca ttttgactga agaataatat gcccagtatt
     2161 tccgtccgcc gactgtttga cgacaaccaa tacaagttac aacttgcctg ggccgccggc
     2221 aattcgggtg cggacaaccg tatcggcgta gaggcggaca agcccgtcct cgctttggtc
     2281 ggacacctga atttcatcca ccccaaccaa atccaagtgg tcggtttggc ggaatcggaa
     2341 tatctgaacc gtctcgaatc gggggaaacg ggttatcagt tcggcgacct gttcgacatt
     2401 tctatgtctt tggttattgt ggcaaacggc ttgccggttt ccccggggct gcgcgactat
     2461 tgccataaaa acgatattcc actgctgact tccaaactcg aaagccccta tctgatggac
     2521 gtgttgcgga tttacctgca acgcaccctg gcggcatcgt ccgtcaaaca cggcgtattt
     2581 ctcgatgtgt ttgaaatcgg cgtgctgatt accggacatt ccggcttggg caagagcgaa
     2641 ttggcgttgg aactgatttc gcgcggccac agcctgattg ccgacgatgc ggtcgagctg
     2701 ttccgcatcg gtccggaaac attggaaggg cgttgttcgc ctatgctgcg tgattttttg
     2761 gaagtgcgcg gcttggggat actcaatatc cgccatattt tcggcgaaac ttccatccgc
     2821 cccaaaaaaa tcctgcaact cattatcaat ttggtcgagg cagacgacga gtatatgaag
     2881 cagctcgacc ggttgagtat ccgcaccgaa accgaatcca tcctcaacgt caacgtccgt
     2941 tcggttacgc tgcccgtcgc cgtcggacgc aacctcgccg ttttggttga ggcggcggta
     3001 cgcaattaca ttttgcagtt gcgcggtaag gacagtacgc gcgaattttt ggaacgccat
     3061 cagacgcaac ttaaagaaaa cgaacagaat catgaaaatc gtcctgatta gcgggttgtc
     3121 cggttcgggc aaatccgtcg cactgcgcca aatggaagat tcgggttatt tctgcgtgga
     3181 caacctgccc ttggaaatgt tgcccgcgct ggtgtcgtat catatcgagc gtgcggacga
     3241 aaccgaattg gcggtcagcg tcgatgtacg ttccggcatt gacatcggac aggcgcggga
     3301 acagattgcc tctctgcgcg gactggggca cagggttgaa gttttgtttg tcgaggcgga
     3361 agaaagcgtg ttggtccgcc ggttttccga aaccaggcga ggacatcctc tgagcaatca
     3421 ggatatgacc ctgttggaaa gcttaaagaa agaacgggaa tggctgttcc cgcttaaaga
     3481 aatcgcctat tgtatcgaca cttccaagat gaatgcccaa cagctccgcc atgcagtccg
     3541 gcagtggctg aaggtcgaac gtaccgggct gctggtgatt ttggagtcct tcgggttcaa
     3601 atacggtgtg ccgaacaacg cggattttat gttcgatatg cgcagtctgc ccaacccgta
     3661 ttacgatccc gagttgaggc cttacaccgg tatggacaag cccgtttggg attatttgga
     3721 cggacagccg cttgtgcagg aaatggttga cgacatcgaa aggtttgtta cgcattggtt
     3781 accgcgtttg gaggatgaaa gcaggagcta cgttaccgtc gccatcggtt gcacgggagg
     3841 acagcaccgt tcggtctata ttgtcgaaaa actcgcccga aggttgaaag ggcgttatga
     3901 attgctgata cggcacagac aggcgcaaaa cctgccgagc cgctaatccc gttgaacgat
     3961 gatgccgtct gaaacccgat tttctgtttc agacggcatt tcaaatattg agaagaaagg
     4021 aaagacatgg caatccaatg gtttcccggc catatgaaca aagcgaaaaa agccatcgcc
     4081 gagcgcgcca aaagcgtaga catggtgatt gaaatgctgg atgcgcgaat gcccgcctcc
     4141 agcgaaaacc ccctgcttgc ccagctttcc aaaggcaaac ccaaacttaa aatcctaaac
     4201 aaacaagatc ttgccgaccc cgaacgcaca aaggtctggc ttgaccacta caacagccgc
     4261 cccgacacgt gcgccattgc cctcgattcc tccgaaaccg gcgcacacgg caaaatcacc
     4321 caagcctgcc gcgcgatgat tccccatcgg caaggcatag acaaaccctt gcgcgtcttg
     4381 atttgcggca ttcccaacgt cggcaaatcc accctcatca acggcatgat aggcaaaaaa
     4441 tccgccaaaa ccggcaacga acccggcatc accaaagccg aacaacgcct tttccttgcc
     4501 gacgacttct ggctgtacga cacccccgga atgctgtggc cgaaaatcat tgtcgaagaa
     4561 agcggctaca acctcgccgc cggcggcgca gtcggacgca acgcattgga cgaagaagaa
     4621 gtcgccctcg aacttttaga ctacctccgc cgccactacc tccctatgtt gcaagaacgc
     4681 taccaagccg acaaagaccc cagcagccac tgggacgaaa acgtttggct cgaatggata
     4741 gccaaaaaac gcggcgcagt cctcagcggc ggacggatca actaccaaaa agccgccgaa
     4801 aacatcctca ccgacttccg tgaaggcaaa atcggcagaa tcaccctcga aacgccgaac
     4861 caatgggaaa cttggctcaa aaaagcccgt cagaaagaag ccgaactcaa agccatacgc
     4921 gaagccagaa aagcagagcg taaagggaag aagccttcgg aagcataaag aatgccgtct
     4981 gaaaaatatt tttcaggcag cttctctcta ctccaaccga tttcagacgg catatccaaa
     5041 cccatgccgt ttcagcacgg atacccgtat gaccgacaaa atttctcccg acgcgctgat
     5101 tgaagccgca ctgctgaccc aaaccgaacc gctgaccgaa aaatctatgc gcgaattgtg
     5161 tgtgccgcca ctgtcgcagg acaaactgat tgatgtgttg gcgcagttga aaacgcgttg
     5221 gcaggatagg gcgttgcaac tggtgcatac gcaagagggc tggcgttttc agattgttca
     5281 gacggcattc gagcggctgg gcagcctgca agaacagcgt gcgccgcgct actcccgcgc
     5341 cgtgatggaa acactggcga ttatcgccta ccagcagccc gtaacgcgcg gcgacatcga
     5401 aggcatacgc ggtgtggcgg tgtcgcagaa cgtgatgcag accttgcagg atcgggggtg
     5461 gattgaagtc atcggacatc gggacacatt gggaaaaccc gcattgtggg cgacaacggc
     5521 aacttttctc agcgatttgc gcttggacgg tctggaagaa cttccgccgc tgaccgaact
     5581 gggcgaactg gttttacccg atttaatgga aatgccgcct acggatgaag aagagccgga
     5641 agccgtaccg tccgataccc tgcccaactg aaattccaaa tgccgtctga aacgcacatt
     5701 gcttcagacg gcatttcaac aaataagcag ataaaaacaa gcactaagca aaattaagga
     5761 aaaacttatt tttaatttaa aaaatcttag ttataattcg tatatctaaa gttgatattg
     5821 cttttgtcgg tagaattgct aaggaatcct cacgatgctt ctaacacttt ctttgcgtga
     5881 ttttgtcatt gtcgaaaatc tgaatctgga ttttcaaagc ggctttaccg tattgaccgg
     5941 agaaactggc gcgggcaagt ccattacttt ggatgcgatt ggtctgctgt tgggcgataa
     6001 agccgattac agccaagtcc gcagcggcgc aaaagaagcg cagttgtcgg cgttgtttga
     6061 tatttcccat ttacctgttt taaaagcaga attgtatgaa caggggcttt taaacgacgg
     6121 agaagaagaa ctcagtatcc gccgcattat cgatgccaaa ggcaaaagcc gcagctttat
     6181 caacaatcag gccgctacct tggcgcaact caaagccgtc ggcagccagc ttatcgacat
     6241 ccatgggcaa aacgcccatc attcgcttaa tcaggaagcc gcccagcgcg aattgttgga
     6301 cgcatttgcg ggcagcaggg cgcaggcgga aaccgtcagg cagctttatc aaaactgggc
     6361 aaactcaaaa aaagcattgc aggaagcgca ggaacaggca gaaaacattg cactcgaaca
     6421 agagcgtctg gaatggcagt ttaacgaatt gaatcagttg gacattaaac aaggcgaatg
     6481 ggaagccctc agccaaagcc acgacagcct tgcccattct gccgagctgt tgcaggctgc
     6541 cgaagaagtc ggaagcaaga ttgacggcga caacggcatc caacgccata tctatcaatg
     6601 tcaaaaacta ttggccaatc tgcaaaacat cgagccgcgc tttgccgaga gcctgaatat
     6661 gttggcaagc atcgaagccg aattgggcga aatcagtgcc aatatgcgcg atgtggcagg
     6721 tcgcagcgac atcaatccca acgaacttgc cgcacaagag cagcgtatgg gcgagctgat
     6781 ggggatggcg cggaaatacc ggatcgagcc tgaagagttg cctgccaagt tggcagaaat
     6841 cgaagaacgc ctgcaaagcc tgcaagctgc cgccgatttg gacgcgctcg agcataatgt
     6901 tgcccacaat tttgccgaat atcaggaagc tgcccacatc ctttctgcca tgcgccatca
     6961 ggcggcagag cgtttgagcg gcgaaacgac cgagcatatg caacaccttg ccatgaaagg
     7021 tgcacgtttc gacatcgtcc tgttgccctc gtcgccgacg gcacacggtt tggagcaggt
     7081 tcaatttcaa gttgccgcca acaaaggcaa tccgccccgt ccgctgaata aagttgcctc
     7141 cggcggcgaa ttggcgcgta tcagccttgc cttacaggtt gttgccagcc aatataccca
     7201 agttcccacc ctgatttttg atgaggtcga taccggtatt ggagggggag tggctgaaat
     7261 ggtcggcaag gcattacgtg cgttgggcag aaaacatcag gtgcttgccg ttacccatct
     7321 tccgcaagtc gcatcctgcg gcgaaaacca ctggcgagtg cgcaagcaca gcgagggaga
     7381 gcaaaccgtc agcgaaatca gtatattgga tgaaatccaa cgggtcgaag aggttgcccg
     7441 tatgttgggc ggagaagtca ttaccgatac gacgcggcaa catgcggcag aattgctgca
     7501 acttgcgtcg aaaaatagtt tattttaaaa tcaatcagtt aaaaaataac taaaaataaa
     7561 agtctaaaac aatagacaga actcagataa atccgtatta ttacgctttc ttaatcactt
     7621 gaacaagtga ttgtgctgca cccgtagctc agttggatag agtatctggc tacgaaccag
     7681 agggtcgggc gttcgaatcg ctccgggtgc gccagtaaga aaatacaata cgcgcccatc
     7741 gtctagcggt taggacatcg ccctttcacg gcggtaaccg gggttcgatt ccccgtgggc
     7801 gtgccaattc aaaatgcctc cgattatatc ggaggcattt ctcatttctc atttctcatt
     7861 tctcatttct catttctcat ttctcatttc tca
//
LOCUS       DAXISH010000079         7842 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.079, whole genome shotgun sequence.
ACCESSION   DAXISH010000079 DAXISH010000000
VERSION     DAXISH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7842
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.079"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(168..1253)
                     /gene="porB"
                     /locus_tag="ACFOV4_001889"
     CDS             complement(168..1253)
                     /gene="porB"
                     /locus_tag="ACFOV4_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric porin PorB"
                     /protein_id="HFC7619839.1"
                     /translation="MKKSLIALTLAALPVAAMADVTLYGTIKAGVEVSRVKDAGTYKA
                     QGGKSKTATQIADFGSKIGFKGQEDLGNGMKAIWQLEQKASIAGTNSGWGNRQSFIGL
                     KGDFGTVRAGNLNTVLKDSGDNVNAWESGSNTEDVLGLGTIGRVESREISVRYDSPVF
                     AGFSGSVQYVPRDNANDVDKYKHTKSSRESYHAGLKYENAGFFGQYAGSFAKYADLNT
                     DAERVAVGATDANPVKDYQVHRVVAGYDANDLYVSVAGQYEAAKNNTVSVGEQGKKHE
                     QTQVAATAAYRFGNVTPRVSYAHGFKAKVNGKKAARYQYDQVIVGADYDFSKRTSALV
                     SVGWLKEGKGVNKTEKTASMVGLSHKF"
     gene            complement(2083..2400)
                     /locus_tag="ACFOV4_001890"
     CDS             complement(2083..2400)
                     /locus_tag="ACFOV4_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFC7619840.1"
                     /translation="MVVRGGIYLVSLDPTVGSEIKKTRPCVVVSPPEIHNYLKTVLIV
                     PMTSGSRPAPFRVNVRFQDKDGLLLPEQIRAVDKAGLVKHLGNLDNSTAEKLFAVLQE
                     MFA"
     gene            complement(2394..2633)
                     /locus_tag="ACFOV4_001891"
     CDS             complement(2394..2633)
                     /locus_tag="ACFOV4_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="growth regulator"
                     /protein_id="HFC7619841.1"
                     /translation="MILNIRKMGNSQGVILPKSLLGQIGAVDSLAVTVEKGNIILSCP
                     TVRRGWAEAAAMLVETEQEHFFSEIENEADKEWIW"
     gene            complement(2756..3553)
                     /gene="truA"
                     /locus_tag="ACFOV4_001892"
     CDS             complement(2756..3553)
                     /gene="truA"
                     /locus_tag="ACFOV4_001892"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFC7619842.1"
                     /translation="MDTAQKQRWAITLSYDGSRFYGWQKQADGVPTVQAALETALAQI
                     AGEAVSTTVAGRTDTGVHATAQVVHFDTTAARPQQAWVRGVNAHLPEGIAVLHARQVA
                     PEFHARFDAYGRHYRYLLESAPVRSPLLKNRAGWTHLKLDIEPMRRAAAYLIGEQDFS
                     SFRAAECQAKSPVKTIYRADLTQSSGLVRLDLHGNAFLHHMVRNIMGALVYVGSGRLS
                     VEGFAALIQERSRLKAPPTFMPDGLYLTGVDYPEAYGIIRPQIPEWL"
     gene            complement(4992..5684)
                     /locus_tag="ACFOV4_001893"
     CDS             complement(4992..5684)
                     /locus_tag="ACFOV4_001893"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HFC7619843.1"
                     /translation="MTAFVHTLSDGMELTVEIKRRAKKNLIIRPAGTHTVRISVPPCF
                     SVSALNRWLYENEAVLRQTLAKTPPPQTAENRLPESILFHSRQLALTAHQDTQILLMP
                     SEIRVPEGAPEKQLALLRDFLERQAHSYLIPRLERHARTTQLFPASSSLTSAKTFWGV
                     CRKTTGIRLNWRLVGAPEYVADYVCIHELCHLAHPDHSPAFWELTRRFAPYTPKAKQW
                     LKIHGRELFALG"
     gene            complement(5681..6424)
                     /locus_tag="ACFOV4_001894"
     CDS             complement(5681..6424)
                     /locus_tag="ACFOV4_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFC7619844.1"
                     /translation="MLIIRNLIYWLILCSTLIFLFPFMLLASPFRDGAHKMARVWVKI
                     LNLSLKHIVGLKYRIIGAENIPDRPAVICAKHQSGWETLALQDIFPPQVYVAKRELFK
                     IPFFGWGLKLVKTIGIDRNNRREANEQLIKQGLVRKNEGYWITIFPEGTRLAPGKRGK
                     YKLGGARMAKMFEMDIVPVALNSGEFWPKNSFLKYPGEITVVICPTIPYASGSEAELM
                     GKCEHLIETQQPLISGAGPFAAKMPSETA"
     gene            complement(6453..7016)
                     /gene="gmhB"
                     /locus_tag="ACFOV4_001895"
     CDS             complement(6453..7016)
                     /gene="gmhB"
                     /locus_tag="ACFOV4_001895"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HFC7619845.1"
                     /translation="MKLIILDRDGVINQDRDDFVKSVDEWIPVEGSMDAVAFLTQAGC
                     TVAVATNQSGIGRKYFTVQNLTEMHAKMHRLVRQAGGEINGIWFCPHTDADNCNCRKP
                     KPGMIEDIIGRFNAQASETWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHEL
                     PEHTQVFDTLLDFSQYIMQENTAPQAD"
     gene            complement(7292..>7842)
                     /locus_tag="ACFOV4_001896"
     CDS             complement(7292..>7842)
                     /locus_tag="ACFOV4_001896"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC7619846.1"
                     /translation="RFFPQPRETAALRAKYGFADHETVFLFPSTGHTRKGLELLADFF
                     EHTDLPVKLAVVGSPLPRPMKNVVGLGFCTDMPELYRAADFTIMASLYEPFGLVGVES
                     VLCGTRVVLSENMACTEVMNEEAGFFFSRQNPETLAQAVAQAVSLKKQGGHRLSDPMR
                     ALNYNPSLSHHIDRLTDILASV"
BASE COUNT         1768 a         1835 c         2275 g         1964 t
ORIGIN      
        1 gactaaaaac aggaaaaagc caaacagaaa acagcgaaac agaaaaaagc caaacagaaa
       61 aaagccaaac agaaaacagc caaacagaaa acagccaaac agaaaaaagc caaacagaaa
      121 aaagcctgtc tggcgacagg ctttttgttg ataccaatct tttcagatta gaatttgtga
      181 ctcaagccaa ccatgctggc agttttttca gttttgttta cgcctttgcc ttctttcaac
      241 caaccgacag aaaccagagc ggaagtgcgt ttggagaagt cgtagtcggc accaacgata
      301 acttggtcgt attgataacg tgctgctttc ttgccattca ctttagcttt gaagccgtga
      361 gcgtaagaaa cgcgaggcgt tacgttgccg aaacggtaag cggcagtagc ggcaacttga
      421 gtttgctcgt gttttttacc ttgttcgccg acactaacag tgttattttt agcagcttca
      481 tactgaccgg caacagaaac gtacaggtca ttggcatcgt aaccggcaac tacgcggtgt
      541 acttggtaat ccttaacagg attggcatct gtagcaccta ctgcaacacg ttctgcatca
      601 gtgttcaaat cagcatattt ggcaaaagag cctgcgtatt gaccgaagaa accggcattt
      661 tcgtatttca gaccggcgtg gtaagactca cggctggact tcgtatgttt gtatttatcc
      721 acatcattcg cattatcgcg cggaacgtat tgtacgctgc cgctgaagcc tgcaaatacg
      781 ggagagtcgt agcgtacgga gatttcacgg ctttctacac gaccgatagt acccagtccc
      841 agtacatctt cggtgttaga accagattcc catgcattga cgttgtcgcc gctgtctttc
      901 aatacggtgt tcagattacc ggcgcggacg gtaccgaagt cgcctttcaa gccgatgaag
      961 gattggcggt taccccagcc gctgttagtg ccggcgatgg aggctttttg ttccaactgc
     1021 caaatggctt tcatgccgtt gccgaggtct tcttgacctt tgaaaccgat tttagaaccg
     1081 aagtcggcaa tttgggttgc agttttagat tttccgcctt gagctttata tgtaccagca
     1141 tcttttacgc gagaaacttc tacgcctgct ttaattgtac cgtacaaggt aacgtcagcc
     1201 attgctgcaa caggcagggc agccagtgtc agggcaatca gggatttttt cattgctgta
     1261 ttccttttca tagttaagaa atttaagcag accaaacttt ccaatccgct taggctttac
     1321 ttctaccgcc gatgtcggcg attccatgtc tgaaactata aatgttcctg tctgaaaaaa
     1381 caaacttctg cctgtttttg tgtggaatcc gatgtgcatt ttgaaggacg gatagagata
     1441 ttatgggtat tttttgtttt ataacatatg gttatttaaa atttttaaga tttgcatttt
     1501 tacaacactt acttgggaag gcattggagg gcattgcaaa ccgggggtta taaagacagc
     1561 aaaaaacgca cacacggttt ctttcggaac gggcggatgc aaaacccgcc cctgcggcag
     1621 gagatagtgg attaacaaaa atcaggacaa ggcgacgaag ccgcagacag tacaaatagt
     1681 acggaaccga ttcacttggt gcttcagcac cttagagaat cgttctcttt gagctaaggc
     1741 gaggcaacgc taaccgtcat tcccgccact tttcgtcatt cccgctcagg cgggaatcta
     1801 gaatctcgga ctttcagata atctttgaat attgccgctg ccttaaggtc tggattcccg
     1861 cctgcgcggg aatgacggct gcagatgccc gacggtcttt agagtggatt aacaaaaatc
     1921 aggacaaggc gacgaagccg cagacagtac aaatagtacg gagccgattc acttggtgct
     1981 tcagcacctt agagaatcgt tctctttgag ctaaggcgag gcaacgccgt actggttttt
     2041 gttaatccac tataatgaac acaatccatt cagactattc aatcaggcaa acatctcctg
     2101 caatactgca aacagttttt cagccgtact gttgtctaaa tttccaagat gtttgaccaa
     2161 tccggcttta tccacagccc taatctgttc gggcaaaagc aaaccgtctt tatcctgaaa
     2221 gcggacattg acgcggaacg gggcaggacg gcttccgctc gtcatgggaa cgatcagcac
     2281 agtcttgaga tagttgtgta tttcaggagg agagactacg acacaaggac gtgtcttttt
     2341 gatttcgctt cctacggtcg ggtctaagga gaccagatag attccgccgc gtactaccat
     2401 atccattctt tatccgcttc gttttcaatt tcggaaaaaa aatgctcctg ctcggtttcg
     2461 acaagcattg cggcagcttc tgcccatccc ctgcgaacgg taggacagct taaaataata
     2521 ttgccctttt caactgtaac agccaagctg tctactgccc ctatttgacc caataatgat
     2581 ttgggcagaa tcacgccttg cgagtttccc attttgcgta tgttgagaat catatacgta
     2641 ccctatttac cagtttatgt aataacaatg ttattacctt gatgaggtag tgtcaatatt
     2701 gaaaaagatt gcctgacagt ttgtccgatt tcaaaatctc cgcgacaaga atgttttaaa
     2761 gccattcggg gatttggggg cggatgatgc cgtatgcctc gggatagtcg acgccggtca
     2821 ggtagagtcc gtcgggcatg aaggtcggtg gggctttgag gcggctgcgt tcttgaatca
     2881 gtgcggcgaa gccttcgacg ctgagtctgc cgctgccgac ataaacgagc gcgcccatga
     2941 tgttgcgtac catatggtgc aaaaaggcgt tgccgtgcaa atcgaggcgg acgagtcctg
     3001 agctttgggt aaggtcggcg cggtagatgg ttttgacggg ggattttgct tggcattcgg
     3061 cggcgcggaa gctggagaag tcttgttcgc cgatcaaata ggcggcagcc cgacgcatcg
     3121 gttcgatgtc gagtttgagg tgtgtccagc ctgccctgtt tttgagcagg ggggaacgga
     3181 cgggggcgga ttcgagcagg tagcggtagt gccgtccgta tgcgtcgaag cgggcgtgaa
     3241 attcgggggc gacctgtcgg gcgtgcaaaa cggcaatgcc ttcgggcagg tgggcattta
     3301 cgccgcgcac ccatgcctgt tggggacggg cggcagttgt gtcgaagtgg acgacttggg
     3361 cggtggcatg cacgccggtg tcggtcctgc cggcaacggt ggtggaaacc gcttcccctg
     3421 ctatttgggc gagcgcggtt tccaatgccg cctgaacggt cggtacgccg tcagcctgtt
     3481 tctgccagcc gtaaaagcgg ctgccgtcat aggatagggt tattgcccag cgttgttttt
     3541 gtgcggtatc catcggattt gggattcgga taaatgttca gactgcattg tatcgcagat
     3601 tttgcaggga aacggcaaac gcccagggcg cgcggcgttg tttggggagt tggggggggt
     3661 ggatgcagtt gctacgaatc gctatcctgt gaattcaccc tgtcaggagt gcccgaatcg
     3721 tcattcccgc gcaggcggga atctaggacg taaaatctaa agaaaccatt ttatagtgga
     3781 ttaacaaaaa ccagtatggc gttgcctcgc cttagctcaa agagaacgat tctctaaggt
     3841 gctgaagcac caagtgaatc ggttccgtac tatctgtact gtctgcggct tcgtcgcctt
     3901 gtcctgattt ttgttaatcc actatatccg ataagtttcc gcaccgacaa aactagattc
     3961 ccactttcgt gggaatgacg ggatgcaggt tcgtgggaat gacgcgaaca gaaacctcaa
     4021 atcccgtcat tcccgcgcag gcgggaatct aggtctgtcg gtgcggaaat ttatcgggaa
     4081 aaaaggtttc tccgtccctg aatcctggat tcccactttc gtgggaatga cggaatgtag
     4141 gttcgtagga atgacgcggt gcaggtttcc gtatggatgg attcgtcatt cccgcgcagg
     4201 cgggaatcta gacattcaat gctaaggcaa tttatcggaa atgactgaaa ctcaaaaaac
     4261 tggattccca ctttcgtggg aatgacgcga acagaaacct caaatcccgt cattcccgcg
     4321 caggcgggaa tctaggtctg tcggtgcgga aacttatcgg gtaaaacggt ttctggagat
     4381 tttgcgtcct ggattcccac tttcgtggga atgacggaat gcaggttcgt aggcatgacg
     4441 cggtgcaggt ttccgtatgg atggattcgt cattcccgcg caggcgggaa tctagacatt
     4501 caatgctaag gcaatttatc ggaaatgact gaaactcaaa aaactggatt cccactttcg
     4561 tgggaatgac gggatgcagg ttttcttaac cccgcgttct agattcccac tttcgtagga
     4621 atgacggcgg tagatttggc agatgcggcg gattcggcag gtctcaaccc atcctacaat
     4681 ccaccctgac cgccttttac gaatccgccg ccatcctggg aaacgcaaaa aaatgccgtc
     4741 cgaaaacctt tcagacggca ttttcgcggg caaatcagta aaagacttcg cgtcagctta
     4801 agcgtttcat accgcacgtc ggaccgggcg ggtttcggaa gagtggtgtg aaatgaaacg
     4861 cggcagacgg cgtgtgtgcc gccatcctgc cccgaaccgg cggcaaagcg tcatcgcggt
     4921 ttgaatcggg cgggcgcgtg cctgttccgg cacggatgcc gtctgaaagc ggcgggtcgg
     4981 tccggtccgc gtcagcctaa ggcgaaaagt tccctgccgt ggattttgag ccactgtttc
     5041 gctttgggcg tgtagggggc gaagcggcgg gtcagttccc aaaaggcggg gctgtggtcg
     5101 ggatgggcga ggtggcagag ttcgtgtatg cagacatagt cggcaacgta ttccggtgcg
     5161 ccgaccagcc gccagttgag gcgtatgcct gtggttttgc ggcacacgcc ccagaaggtt
     5221 ttggcagagg tcagcgagga ggaggcgggg aacagttgtg tggtgcgggc gtggcgttcg
     5281 aggcggggaa tcaggtaact gtgcgcctgc cgttccaaaa agtcccgcag cagcgcaagc
     5341 tgtttttcgg gtgcgccttc gggaacacgg atttcagacg gcatcagcag gatttgcgtg
     5401 tcttgatggg cggtgagggc aagctgtctg ctgtggaaga ggatggattc gggcagccgg
     5461 ttttcggcag tttgcggcgg cggtgttttc gccagtgttt gccgcaggac ggcttcgttt
     5521 tcatacagcc agcggtttag agcggagacg gagaagcagg gtgggacgct gatgcggacg
     5581 gtatgtgtgc cggcggggcg gataatcagg tttttcttgg cacggcgctt gatttcgacg
     5641 gtcagttcca tgccgtctga aagggtgtgg acaaaggcgg tcatgcggtt tcagacggca
     5701 ttttggcggc aaacgggcct gcgccggaaa tgagcggctg ctgcgtttcg atgaggtgtt
     5761 cgcattttcc catcaattcg gcttcgctgc cgcttgcgta cgggatggtc ggacagatga
     5821 cgacggtgat ttcccccgga tatttcagaa aggagttttt cggccaaaat tcgccgctgt
     5881 tgagggcgac ggggacgatg tccatctcaa acattttcgc catgcgcgcg ccgccgagtt
     5941 tgtatttgcc gcgttttccg ggcgcaaggc gcgtgccttc ggggaaaatg gtaatccaat
     6001 agccttcgtt tttgcgcacc aacccctgtt ttatgagctg ctcgttggct tcgcggcggt
     6061 tgttgcggtc tatgcctatg gttttgacca gtttcaagcc ccagccgaaa aaggggattt
     6121 tgaacaactc gcgtttggca acgtaaacct gcggcggaaa aatgtcctga agggcgagcg
     6181 tttcccagcc gctttggtgt ttggcgcaga tgacggcggg gcggtcgggg atgttttccg
     6241 cgccgatgat gcggtatttg agcccgacga tgtgtttgag cgagaggttg aggattttga
     6301 cccagacccg cgccatcttg tgcgccccgt ctcggaaagg cgaggcgagc agcataaagg
     6361 gaaagaggaa aatcagggtg gaacagagta tcagccagta aatcaggttg cggatgatga
     6421 gcatggtttt gccttgtcgg aatgcggtat gttcagtcgg cttgcggtgc ggtgttttcc
     6481 tgcatgatgt attgtgagaa atcgagcagg gtatcgaaaa cctgtgtgtg ttcgggcaat
     6541 tcgtgtccgt gttgggagag cgtttttttg ccttttccgg tcagaaccag cgcgggtttg
     6601 ccgccgacgg catcgattgc ctgcaaatcg cgcaggctgt cgccgaccag ccaggtttcc
     6661 gaggcttggg cgttgaagcg tccgatgatg tcttcaatca tacccggttt gggcttgcgg
     6721 cagttgcagt tgtcggcatc ggtgtgcggg cagaaccaga tgccgttgat ttcgccgcct
     6781 gcctgacgga cgaggcggtg cattttggcg tgcatttcgg taaggttttg aacggtaaaa
     6841 tatttgcgcc cgatgccgga ttggttggtg gcaacggcga cggtgcagcc tgcctgcgtc
     6901 agaaatgcca ccgcatccat gctgccttcg acaggtatcc actcgtcaac ggatttgacg
     6961 aagtcatcgc ggtcctgatt gatgacgccg tcgcggtcga gaatgatgag tttcatcgcg
     7021 tttcctttgg gttggggcag gtcgggggtg gcattatact gaaatatcgg cagtgatgcg
     7081 cctgtgccgc gtgatatagt ggattaacaa aaaccagtac ggtattgcct cgccttagct
     7141 caaagagaac gattctctaa ggtgctgaag caccaagtga atcggttccg tactatctgt
     7201 actgtctgcg gcttcgttgc cttgtcctga tttttgttaa tccactataa cgcagcaatg
     7261 ccgtctgaaa actcgttcag acggcatttt gttatacgga tgccagtatg tcggtcagtc
     7321 ggtcgatgtg gtgcgacagg gacgggttgt agttcagtgc acgcatcggg tcggacaggc
     7381 ggtgtccgcc ctgtttttta aggctgacgg cttgggcaac ggcttgcgct agggtttccg
     7441 ggttttggcg tgagaaaaag aatccggctt cttcgttcat gacctctgta catgccatgt
     7501 tttcggagag gacgacgcgt gtgccgcata ggacggattc gacaccgacc agcccgaagg
     7561 gttcatacag ggaggccata atggtaaagt cggcggcgcg gtagagttcg ggcatatcgg
     7621 tgcagaagcc cagtccgacg acgtttttca tagggcgggg gagcggggag ccgacaacgg
     7681 caagcttgac gggcaggtcg gtatgttcga aaaagtcggc aagcagttcc aggcctttgc
     7741 gcgtgtggcc ggtcgatgga aataggaaaa cggtttcatg gtcggcaaaa ccgtatttgg
     7801 cgcgcagagc ggcagtttct ctaggttgtg gaaagaagcg tt
//
LOCUS       DAXISH010000080         7824 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.080, whole genome shotgun sequence.
ACCESSION   DAXISH010000080 DAXISH010000000
VERSION     DAXISH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7824
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.080"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(84..839)
                     /locus_tag="ACFOV4_001897"
     CDS             complement(84..839)
                     /locus_tag="ACFOV4_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HFC7619847.1"
                     /translation="MKFARLLFLCAALAGTQAAAAEMVQIEGGSYRPLYLKKDTGLIK
                     VKPFKLDKYPVTNAEFAEFVNSHPQWQKGRIGSKQAEPAYLKHWMKNGSRSYAPKAGE
                     LKQPVTNVSWFAANAYCAAQGKRLPTIDEWEFAGLASATQKNGSNEPGYNRTILDWYA
                     DGGRKGLHDVGKGRPNYWGVYDMHGLIWEWTEDFNSSLLSSGNANAQMFCSGASIGSS
                     DSSNYAAFLRYGIRTSLQSKYVLHNLGFRCTSR"
     gene            complement(1019..2178)
                     /gene="nirK"
                     /locus_tag="ACFOV4_001898"
                     /pseudo
     CDS             complement(1019..2178)
                     /gene="nirK"
                     /locus_tag="ACFOV4_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714409.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0050421 - nitrite reductase (NO-forming)
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="copper-containing nitrite reductase"
     gene            2558..4813
                     /locus_tag="ACFOV4_001899"
     CDS             2558..4813
                     /locus_tag="ACFOV4_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric-oxide reductase large subunit"
                     /protein_id="HFC7619848.1"
                     /translation="MGQYKKLWYLLFAVLAVCFTILGYMGSEVYKKAPPYPEQVVSAS
                     GKVLMTKDDILAGQSAWQSTGGMEVGSILGHGAYQAPDWTADWLHRELSAWLDLTAQQ
                     TYGKKFDEVSPEEQAVLKTRLADEYRNQSRIKEDGSVVISDTRVKAIESILPYYHGVY
                     GDDPALQTTREHFAMKNNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHE
                     PLINNVPTTENYMWSFTSVVLLLMGIGLLMWGYSFLTKHEEVEVPSEDPISKIQLTPS
                     QKALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGFEMSDWFPYALTRTW
                     HIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIALFIVVGGSYAGNFFA
                     LTHILPPEFNFWFGHQGYEYLDLGRFWQLLLMVGLLLWLFLMLRCTVSAFKEKGVDKN
                     LLAIFVASMVGVGVFYAPGLFYGEKSPIAVMEYWRWWVVHLWVEGFFEVFATAAFAFV
                     FYNMGFVRRSTATASTLAAAAIFMLGGVPGTLHHLYFSGSTSASMAIGACFSALEVVP
                     LVLLGREAYEHWSYQHLSDWAKRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYI
                     QGLNTSAVHAHAALFGVYGFLALGFVLLVARYLKPNAQFDDKLMTWGFWLLNGGLVGM
                     IVISLLPVGAIQAYASITHGLWYARSEEFLQMEILDTLRWVRTAADLIFIGGAVCVAI
                     QATKIVFSRDK"
     gene            4992..5525
                     /locus_tag="ACFOV4_001900"
     CDS             4992..5525
                     /locus_tag="ACFOV4_001900"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFC7619849.1"
                     /translation="MGIYDFQMKDAEGNAVDLSGYRGKVLLIVNTATRCGLTPQYEAL
                     QKLYAQYTAEGLEILDFPCNQFREQAPESSGEIAQVCMMKFGTKFKIFDKIEVNGANT
                     APLYAYLKSVKPQDKGNHLFKDFVLKLAALGEKRDEGDIKWNFTKFLVNRDGEVVERF
                     APSVTPEEIEADIRALL"
     gene            complement(5588..6772)
                     /locus_tag="ACFOV4_001901"
     CDS             complement(5588..6772)
                     /locus_tag="ACFOV4_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HFC7619850.1"
                     /translation="MTEPTSRRRFLKTCTAAAGAGLLQACGTSATSVPPLPSSHSVVK
                     ARTVPLQTPRRQSSDGNLLRIVASSGFAEDTNRVNTALTRLYNASFTVTNQQAGSRRF
                     QRFAGTDTQRAADFQEVASGRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGT
                     LFFGFSDVCAVQLALLAKGNMMSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVD
                     VPYIQRADVETEGILWGGNLSVLASLAGTPYMPDIDGGILFLEDVGEQPYRIERMLNT
                     LYLSGILKKQRAIVFGNFRMEKIRDVYDPSYDFSAVANHVSRTAKIPVLTGFPFGHIA
                     DKITFPLGAHARIRMNGNSGYSVAFEGYPTLDASALTLDTLLPPPDLPIFPESGVADI
                     SE"
     gene            complement(6812..7216)
                     /locus_tag="ACFOV4_001902"
     CDS             complement(6812..7216)
                     /locus_tag="ACFOV4_001902"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFC7619851.1"
                     /translation="MTAQPCPICTAQDEDVLLQTAKLRVIAVHNDSGSPTFCRVIWRK
                     HIAEMTDLSAAERGELMEIVYKVEAAMRQVFRPAKINLASLGNVVPHLHWHIIARFEN
                     DASFPAPIWANPVRKHGMTLPQDWTEQLKKLL"
BASE COUNT         1760 a         1893 c         2161 g         2010 t
ORIGIN      
        1 aatatagcgg attaacaaaa accagtacgg caaggcgagg caacgccgta ctggtttttg
       61 ttaatccact ataattgaag gggttatcgg cttgtgcaac ggaagcccaa gttgtgcaag
      121 acgtatttgg attgcaggct ggtgcggatg ccgtagcgga ggaaggcggc atagttggac
      181 gagtcgctcg acccgataga cgcgccgctg caaaacattt gcgcgttggc attgccggaa
      241 gaaagcaggc tgctgttgaa atcttccgtc cattcccaaa tcagcccgtg catatcataa
      301 acgccccagt agttcgggcg gcctttgccg acatcgtgca ggcctttccg tccgccgtcg
      361 gcataccaat cgagaatagt gcggttgtag ccgggttcgt ttgagccgtt tttctgcgtg
      421 gcggaagcaa gtccggcaaa ttcccattcg tcaatggtcg gcaggcgttt gccttgtgcg
      481 gcgcaatagg cgttggcggc aaaccaggaa acattggtta ccggttgttt taattcgccc
      541 gccttcggcg catagctgcg gctgccgttt ttcatccaat gcttcaggta agcgggttct
      601 gcctgtttgg aaccgatcct gcctttttgc cattgggggt ggctgttgac aaattcggca
      661 aactcggcat tggtaacggg atatttatcc agtttgaacg gtttgacttt aatcaggccg
      721 gtatcttttt tcagataaag cgggcggtag ctgccgcctt cgatttgaac catttcggca
      781 gccgccgctt gagtgccggc gagtgccgca cagagaaaga gtaaccgggc aaacttcata
      841 tcatgcctcc tgacaggcag ttaaaattga tttttcagac ggcattttaa acaaaaagcc
      901 gcgaatgccg tctgaagaat caatcttccg aaaggaaaga ttggttgtta aaaaaccact
      961 gccgtgcgta attaagtacg gcggcagtgg ttcgtttgcc taaaaatggg tgttcaattt
     1021 agtaatcgct ttttgcagga gcagaggctg caggagcaga agctgcggga gcggaagcag
     1081 caggagctgc accgttaccg gcgtaagcgg tatcactcaa tttttgagtc atgatttcag
     1141 ggttttctgc accttctact ttcaattgac ccagtgcgcc tttgttgaat gcgcggaaga
     1201 tagagtggtc aaccaaagtg tagctgcccg ggatgtcgac tttgaattcg acgatggcag
     1261 agccgccggc aggaacgatg gtactttgta cgttttcgtt aatcagtttg ccgccttcaa
     1321 cataaacttt gtcgaagatt tcaccgatta cgtggaagga agacaccaag ttcgggccgc
     1381 cgttaccaac gtacatacgt acagtttcgc ctgctttggc tttcagggcg ttgtcgccgg
     1441 cgatagcacc tacgtgaccg ttgaatacga cgtattcagg ctgttcggca acagctttgt
     1501 ccatatcgaa cggttgcagg ccttgcgcac cttttttgcc tttggtgtag aagtcgcctt
     1561 ggacgatgta gaactcttta tccactttcg gcaggccttc tttaggctcg accaaaatca
     1621 ggccgtacat accgttggcg atgtgcatac cgaccggcgc gacggcgcag tggtagatgt
     1681 acagacccgg ttgcagggct ttgaagctga atgtggaagt gcggcccggg cggtaaaggt
     1741 cgcggctgca ccgccgccct gaccggttgc ggcgtggaag tcgacgttgt gcggaacggt
     1801 agaagaagga ttgttggaaa attccacttc aaccgtatcg ccttcgcgta cgcggatcat
     1861 gcgacccgga acgtcgccgt caaatgtcca gtagcggtat tccacaccgt cttccatggt
     1921 catggttttt tcgacggttt ccattttcac gcgtactttg gcagggtagt cgcggtcgat
     1981 tgcaggaggt acttctggag cgtgtgtggt aaccgcatcg ataacgggca gttcgcctgt
     2041 cggcgtttcg gcggcggttt gtgcggcgga acttgcggct tctgcggaag cggcaggggc
     2101 ttgcgcggca ggttcgccgc cgcaggcggc taatgcgaat aaggaagcaa tcattgcagc
     2161 taaggcttgg cgtttcataa tattttcctt ttgtaagaaa agtagaggga ttggttaaga
     2221 acttggtgtg attatgcgtt tgccccattg ggggcatttt gatttaagtc aaataattca
     2281 taaaatatga acttaaaatg atacttctaa tactttatag ctactaaaaa ttacaataaa
     2341 taggctgatt tgcttaagga cttcggcaaa tcaggcaaag gcagggtagt tgccgactaa
     2401 agaataatga tagttattat catatatgta tttgttttat atgtgagttt ctttaaacaa
     2461 atgtttattt gcgcggtaaa ccgtgataca atctttaaca ttcatatttg atgaattaat
     2521 acccaaccac ttttaccaaa attaaggagt acttaaaatg ggacagtaca agaagctgtg
     2581 gtacttgctg tttgccgttc tggcggtatg ctttaccatt cttggctata tgggcagcga
     2641 ggtttataag aaagccccgc cttaccccga acaggtcgtt tccgcatcag gcaaagtgct
     2701 gatgacgaaa gacgatattt tggcaggtca gtctgcgtgg cagagtaccg gcggtatgga
     2761 agtcggttcg attctgggtc acggcgcata tcaggctccg gactggacgg ccgactggct
     2821 gcatcgtgag ttgtccgcct ggttggattt gaccgcgcaa cagacttacg gcaaaaaatt
     2881 cgatgaagtt tcccctgaag aacaagccgt tctgaaaacc cgactggctg acgaataccg
     2941 caaccaaagc cgtattaaag aagacggcag cgtcgtcatc agcgatacgc gcgtgaaagc
     3001 catcgaaagc atcctgcctt attaccacgg tgtttacggc gatgatcccg cgctgcaaac
     3061 cacccgcgaa cactttgcaa tgaaaaacaa cacattgcca agccaagaag cgcgtgaaaa
     3121 actgttcgac ttcttcttct ggacttcttg gtctgcttcg accaaccgtc ctgacgagac
     3181 gttcacttat accaacaact ggccgcacga gcctttgatc aacaacgtac cgaccactga
     3241 aaactatatg tggtcattca ccagcgttgt tcttctgctg atgggcatcg gtttgctgat
     3301 gtggggttat tccttcttga ccaaacacga ggaagtggaa gtgccgtctg aagacccgat
     3361 ttccaaaatc caactgaccc cttcgcaaaa agcattgggc aaatacgtct tcctgacggt
     3421 cgccctgttt gtggtacaag tattgctggg cggactgacc gcgcactaca ccgtcgaagg
     3481 ccagggtttc tacggcattg acgaggcgtt gggctttgaa atgtccgact ggttccccta
     3541 cgccctgacc cgtacttggc acatccaatc cgccatcttc tggattgcaa ccggcttttt
     3601 gacggcaggt ttgttcctcg cgccgattgt caacggcggt aaagatccca agttccaacg
     3661 tgccggcgta aacttcctct atatcgccct cttcatcgtg gtcggcggtt cttacgcggg
     3721 caacttcttc gcgttgacgc acatccttcc ccccgaattt aatttctggt tcggacacca
     3781 aggttacgaa tacctcgatt tgggtcgttt ctggcaactc cttttgatgg tcggactgct
     3841 gttgtggctg ttcctgatgt tgcgctgcac ggtttccgcc ttcaaagaaa aaggcgtgga
     3901 caaaaacctg ctggcaatct ttgtcgcttc tatggtcggt gtgggcgtgt tctacgcacc
     3961 gggactgttc tatggcgaaa aatccccgat tgccgtaatg gaatactggc gttggtgggt
     4021 ggttcacctg tgggtggaag gcttctttga agtatttgcc actgccgcct ttgcctttgt
     4081 cttctacaat atgggctttg ttcgccgcag taccgccact gcctccactt tggcagctgc
     4141 cgccatcttt atgttgggcg gcgttcccgg tacgctgcac cacctgtact tctccggctc
     4201 tacctccgcc tctatggcaa tcggcgcctg cttctccgct ttggaagtcg tgccgctggt
     4261 gttgctgggc cgtgaagcat acgagcattg gtcttaccaa cacctgtccg actgggcgaa
     4321 acgcctgcgt tggccgctga tgtgcttcgt ggcagtcgcc ttttggaata tgatcggtgc
     4381 cggtgtattc ggtttcctga ttaacccgcc gatttccctg ttctatatcc aaggtttgaa
     4441 tacttctgct gttcatgcgc acgccgcctt gttcggtgtg tacggtttct tggcattggg
     4501 cttcgtattg ctggttgccc gttatttgaa accgaacgcg cagtttgacg acaaactgat
     4561 gacttggggc ttctggctgc tcaacggcgg tttggtcggc atgattgtta tcagcctgct
     4621 gcctgtcggt gctattcaag catatgcctc tattactcac ggtttgtggt atgcccgcag
     4681 cgaagaattc ctgcaaatgg aaattctcga caccctgcgc tgggtacgta cggcagctga
     4741 cttgatcttt atcggcggtg ctgtttgcgt tgctatccaa gctaccaaaa tcgtattcag
     4801 ccgcgataaa taagttttgc ggtatgaaat gagcaactgc acccgttttc gggtgcagtt
     4861 ttttattgcg gattgggacg ggaatggaaa aggatgtgga ttttttattt taatcggcta
     4921 tacaattgct gctttcatgc cgtctgaagc acgtttcaga tggcatcggt ttacatcaga
     4981 taaggataaa aatgggtatt tacgattttc aaatgaaaga tgcggaaggc aatgcggttg
     5041 atttgtcagg ctatcgcggc aaggttctgc tgattgtcaa cacggcaacg cgttgcggtc
     5101 tgaccccgca atacgaggct ttgcagaagc tgtatgcaca atataccgca gaaggcttgg
     5161 agattttgga ttttccgtgc aaccagttcc gcgaacaggc tcccgaaagc agcggagaaa
     5221 ttgcccaagt gtgtatgatg aagtttggca cgaagtttaa gattttcgac aaaatcgaag
     5281 tcaatggagc aaataccgcg cccttgtatg cctacctgaa atccgtcaaa ccgcaagata
     5341 aaggcaatca tctgtttaaa gatttcgtgt tgaagctcgc agctttggga gagaagcgcg
     5401 acgaaggcga catcaaatgg aactttacca aattcctcgt caaccgcgac ggcgaagtgg
     5461 tcgagcgttt tgcgcctagt gttacgcccg aagaaatcga agccgatatt cgggcattgc
     5521 tgtaatctgc cgccgtcttg ggaaatgccg tctgaaggct tcagacggca tttgtccgtt
     5581 tgcgggttta ttccgaaata tcggcaacac cgctttcggg gaagatgggc aaatccggcg
     5641 gtgggagcag ggtatccaaa gtcagggcgg acgcatcgag tgtggggtag ccttcaaacg
     5701 cgaccgaata accgctgttt ccgttcatac ggattcgggc gtgcgcgccc agagggaaag
     5761 tgattttgtc ggcaatgtgc ccgaagggaa agcccgtcag cacggggatt ttcgccgtgc
     5821 gcgaaacatg gttggcaacg gcggaaaaat cataagacgg atcatagaca tctcgaattt
     5881 tttccatacg gaaattgccg aacacgatgg cgcgctgttt cttcaaaata cccgaaagat
     5941 acagcgtatt gagcatacgt tcgatgcggt agggctgttc gccgacatct tcgaggaaca
     6001 aaatgccgcc gtcgatgtcg ggcatataag gcgtgccggc gagcgaggcg aggacgctta
     6061 agttgccgcc ccacaatatg ccttcggttt cgacatcggc gcgttggata taaggaacat
     6121 caacggtcag gcggttttgg gttgcaccct tgataaaggc atccatcgta aacgcaccgg
     6181 gggcgggttt gccaaaatcg ctataagcca tcgggccggc aaaactcatc atattgcctt
     6241 ttgccaacaa tgccagctgg acggcgcata cgtcgctgaa tccgaaaaac agcgtgccgt
     6301 gttcgcgcat ccttgcgccg agcgaagcaa aatcgatatg cggcagaatc cgcgccgcac
     6361 cgtaaccgcc gcgcaagccc atcagcactt taggcgtggc gacgcggccg gaagcgacct
     6421 cttggaaatc ggcggcacgt tgcgtgtccg taccagcaaa ccgttggaag cggcggctgc
     6481 ccgcctgttg gttggttacg gtaaaactgg cattgtaaag gcgggttaag gctgtgttga
     6541 cgcggttggt gtcttcggca aatcctgacg aagcgacaat gcgcagaagg ttgccgtccg
     6601 aactttgacg gcgtggcgtt tggagaggca cggttcgggc tttcacaacg gaatgggaag
     6661 agggaagggg cggaacggat gtggcggatg tgccgcaagc ctgaagcagt cccgcgcctg
     6721 cggcggcggt gcaggttttc aggaaacggc ggcgggaggt cggttcggtc ataatttccc
     6781 tttcatacgg tttcagacgg catcggcggg cttaaagcag ctttttaagc tgttccgtcc
     6841 aatcttgcgg cagggtcata ccgtgttttc ggacggggtt tgcccaaatc ggcgcgggga
     6901 aggacgcatc gttttcaaag cgggcgataa tatgccagtg caggtgcggc acgacattgc
     6961 ccaagctggc gaggttgatt tttgccggcc ggaacacttg gcgcatagcg gcttcgactt
     7021 tgtacactat ttccatcaat tcgccgcgtt ccgctgccga aaggtcggtc atttcggcaa
     7081 tatgcttacg ccaaatgacg cggcagaatg tcggcgaacc gctgtcgtta tggacggcga
     7141 tgacgcgcag cttggcggtt tgcaacaaaa cgtcttcatc ttgcgccgtg cagatggggc
     7201 agggttgggc ggtcattttt ccttattcct gaaagtgttt aaaaaacggt agggtaattt
     7261 ctgatatagc ggattaacaa aaatcaggaa aaggcgacga agccgcagac agtacagata
     7321 gtacggaacc gattcacttg gtgcttgagc accttagaga atcgttctct ttgagctaag
     7381 gcgaggcaac gccgtactgg tttaaattta atccactata gtttaatttg tctgtccgca
     7441 ttgccgctaa ttgtaccact tcatcgtatt tccttttcgg ttgaaacccc gccctttagg
     7501 gcggcaggat cagactttat ttgggagggg gtgtaacccc ttccaaatca ggacgacaca
     7561 tagggaggtg ctttatgtgt cgtcctgtgt gttgaaacat atcggacgcg tttgaacagt
     7621 tgtgcggcaa actgttttag cggcaggcaa gagatgccgt ctgatgccgt ctgaagccca
     7681 ttgtccgtca ttcccacaca ggcagttgct acggttgctg aagcccctta gccgtcgcgc
     7741 aggcggttgc tacggttact aaaatcccgt cattcccgcg caggcgggaa tccagtccgt
     7801 tcggtttcag ttgtttctaa ataa
//
LOCUS       DAXISH010000081         7799 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.081, whole genome shotgun sequence.
ACCESSION   DAXISH010000081 DAXISH010000000
VERSION     DAXISH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7799
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.081"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(43..459)
                     /gene="dksA"
                     /locus_tag="ACFOV4_001903"
     CDS             complement(43..459)
                     /gene="dksA"
                     /locus_tag="ACFOV4_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0019899 - enzyme binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HFC7619852.1"
                     /translation="MAKLTEQDILNWSGPEDDYMNDDHLAFFRELLVKMQDELIENAS
                     ATTGHLQEHESAPDPADRATQEEEYALELRTRDRERKLLSKIQATIRNIDEGDYGFCA
                     DTGEPIGLKRLLARPTATLSVESQERRERMKKQFAD"
     gene            complement(606..1415)
                     /gene="proC"
                     /locus_tag="ACFOV4_001904"
     CDS             complement(606..1415)
                     /gene="proC"
                     /locus_tag="ACFOV4_001904"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFC7619853.1"
                     /translation="MNRVEIMNVYFLGGGNMAAAVAGGLVKQGGYRIHIANRGAEKRE
                     RLQKELGVETSETLPELHSDDVLILAVKPQDMEAACKNIRTNGALVLSVAAGLPVDTL
                     SRYLGGTRRIVRVMPNTPGKIGLGVSGMYAEAEVSETDRRIADRIMKSVGLTVWLEDE
                     AQMHSITGISGSGPAYVFYLLDALQNAAIRQGFDMAEARALSLATFKGAVTLAEQTGE
                     DFEKLQKNVTSKGGTTHEAVEAFRRHRVAEAISEGVCACVRRSQEMERQYQ"
     gene            complement(1446..1853)
                     /locus_tag="ACFOV4_001905"
     CDS             complement(1446..1853)
                     /locus_tag="ACFOV4_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFC7619854.1"
                     /translation="MEIRAIKYTAMAALLAFTVAGCQLAGWYECSSLSGWCKPRKPAA
                     IDFWDIGGESPPSLEDYEIPLSDGNRSVRANEYESAQQSYFYRKIGKFEACGLDWRTR
                     DGKPLIETFKQGGFDCLEKQGLRRNGLSERVRW"
     gene            complement(1853..2539)
                     /locus_tag="ACFOV4_001906"
     CDS             complement(1853..2539)
                     /locus_tag="ACFOV4_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFC7619855.1"
                     /translation="MTVLQERYREVSDRIGKLVLQAGRKPHSVSLIAVGKTFPSDGIR
                     EVYAAGQRDFGENYIQEWYGKTEELADLTDIVWHVIGDVQSNKTKFVAERAHWVHTVC
                     RLKTAVRLSEQRPSSMPPLQVCIEVNIAGEAVKHGVAPEEAVALAVEVAKLPNIVVRG
                     LMCVAKANSSETELKVQFQTMRKLLADLNTAGVKADVLSMGMSDDMPAAIECGATHVR
                     IGSAIFGKRG"
     gene            2659..3702
                     /gene="pilT"
                     /locus_tag="ACFOV4_001907"
     CDS             2659..3702
                     /gene="pilT"
                     /locus_tag="ACFOV4_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HFC7619856.1"
                     /translation="MQITDLLAFGAKNKASDLHLSSGISPMIRVHGDMRRINLPEMSA
                     EEVGNMVTSVMNDHQRKIYQQNLEVDFSFELPNVARFRVNAFNTGRGPAAVFRTIPST
                     VLSLEELKAPSIFQKIAESPRGMVLVTGPTGSGKSTTLAAMINYINETQPAHILTIED
                     PIEFVHQSKKSLINQRELHQHTLSFANALRSALREDPDVILVGEMRDPETIGLALTAA
                     ETGHLVFGTLHTTGAAKTVDRIVDVFPAGEKEMVRSMLSESLTAVISQNLLKTHDGNG
                     RVASHEILIANPAVRNLIRENKITQINSVLQTGQASGMQTMDQSLQSLVRQGLIAPEV
                     ARRRAQNSESMSF"
     gene            3865..5091
                     /locus_tag="ACFOV4_001908"
     CDS             3865..5091
                     /locus_tag="ACFOV4_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="HFC7619857.1"
                     /translation="MNTDNLHDILDEMVQVYSQKKQSRSETPAEIGAHFHPLLDRLCE
                     TAEAQNASDILISKGFPPSLKINSALTPQPQKALTGEETAAIAASTMNAEQSEIFRRD
                     GEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRG
                     LLIIVGPTGSGKSTTMATMLEHRNKTLPSHIVTIEDPIEFIYKPRRCIFTQREIGVDT
                     INWQTAVQNAMRQSPDVVCIGEVRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERI
                     LNFYPKEQHNQILIDIALNLTGIICQRLALKQDKTGRTAVVDLLINTPAIQDFILKGD
                     LMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGK
                     TPELLYDRVNGLNLIS"
     gene            5377..7527
                     /gene="yccS"
                     /locus_tag="ACFOV4_001909"
     CDS             5377..7527
                     /gene="yccS"
                     /locus_tag="ACFOV4_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YccS family putative transporter"
                     /protein_id="HFC7619858.1"
                     /translation="MKTPLLKPLLITSLPVFASVFTAASIVWQLGEPKLAMPFVLGII
                     AGGLVDLDNRLTGRLKNIIATVALFTLSSLTAQSTLGTGLPFILAMTLMTFGFTILGA
                     VGLKYRTFAFGALAVATYTTLTYTPETYWLTNPFMILCGTVLYSTAIILFQIILPHRP
                     VQESVANAYDALGGYLEAKADFFDPDEAAWIGNRHIDLAMSNTGVITAFNQCRSALFY
                     RLRGKHRHPRTAKMLRYYFAAQDIHERISSAHVDYQEMSEKFKNTDIIFRIHRLLEMQ
                     GQACRNTAQALRASKDYVYSKRLGRAIEGCRQSLRLLSDGNDSPDIRHLRRLLDNLGS
                     VDQQFRQLQHNGLQAENDRMGDTRIAALETSSLKNTWQAIRPQLNLESGVFRHAVRLS
                     LVVAAACTIVEALNLNLGYWILLTALFVCQPNYTATKSRVRQRIAGTVLGVIVGSLVP
                     YFTPSVETKLWIVVVSTTLFFMTRTYKYSFSTFFITIQALTSLSLAGLDVYAAMPVRI
                     IDTIIGASLAWAAVSYLWPDWKYLTLERTAALAVCSNGAYLEKITERLKSGETGDDVE
                     YRATRRRAHEHTAALSSTLSDMSSEPAKFADSLQPGFTLLKTGYALTGYISALGAYRS
                     EMHEECSPDFTSQFHLAAEHTAHIFQHLPETEPDDFQTALDTLRGELDTLRTHSSGTQ
                     SHILLQQLQLIARQLEPYYRAYRQIPHRQPQNAA"
BASE COUNT         1899 a         2584 c         1720 g         1596 t
ORIGIN      
        1 gtctgaaact tagggcttca gacggcattt tgtttgccgc catcagtcgg caaactgttt
       61 tttcatcctc tctcggcgtt cttgggactc aacagataaa gtggctgtcg ggcgtgccag
      121 cagccgcttc agaccgatag gctctcccgt atcggcacag aatccataat ccccttcatc
      181 aatattgcgg atggtcgcct gtattttact gagaagtttt cgttcccgat cgcgggtacg
      241 gagttccaat gcgtactctt cttcctgtgt ggcacggtcg gcaggatcgg gggctgattc
      301 gtgttcttgg agatgccctg tcgtagcgga agcattttcg atgagttcgt cttgcatttt
      361 taccagcaat tcgcggaaaa aagccaaatg gtcgtcattc atataatcgt cttccggccc
      421 gctccaattc aaaatatctt gttctgtcag ctttgccata atgtatatcc tctcggttca
      481 ccgaaaaaaa caaagcacca caaagtggct ttattccttt gatttttata aggcttattg
      541 cctaaggcgt ttttgaaaac gcgcatcata acacgttttg gattggtttt tttattttct
      601 ttacattatt gatattgccg ttccatttcc tgcgaacggc gcacacaggc acaaacgccc
      661 tcacttatgg cttcggcgac acgatgccgc ctgaaggctt ccacggcttc gtgggttgtc
      721 ccgccttttg acgttacatt tttttgaagc ttctcgaaat cttcacccgt ctgctcggca
      781 agggtaaccg ctcctttaaa cgttgccaga ctgagcgcgc gtgcttctgc catatcaaac
      841 ccttgtcgga tggcggcatt ttgcaatgcg tccagcagat aaaacacata tgccggcccg
      901 ctgccgctga taccggtaat gctgtgcatt tgcgcttcat cttccaacca aacagtcaaa
      961 ccgactgatt tcatgattcg atcggcaatc ctgcggtctg tttccgatac ttccgcttcg
     1021 gcatacatac cggatacgcc cagcccgatt tttccgggtg tattcggcat aacccggaca
     1081 atgcggcgtg ttcccccgag gtaacggctg agcgtatcga ccggcaatcc ggctgcgaca
     1141 gaaagcacca atgcgccgtt ggtgcggata tttttgcacg cggcttccat atcctgcggc
     1201 ttgacggcaa ggattaaaac atcgtcggaa tgaagctccg gcaaggtttc agaagtttcg
     1261 acccccaact ctttttgcaa acgttcgcgc ttttccgcac cccggttggc aatatggatg
     1321 cggtaaccgc cttgtttgac caatccgccc gcaacggcag ccgccatatt gccgccgccg
     1381 agaaaataaa cattcattat ttctacccta ttcaaaatta cctgactaaa ttcattccca
     1441 attttttacc atcggacgcg ctcggacaga ccgttgcgcc gcaacccctg cttttccaag
     1501 cagtcaaatc ctccctgttt gaacgtctca atcaaaggtt tgccgtcacg cgtacgccaa
     1561 tccagcccgc aggcttcaaa cttccctatt ttcctgtaaa agtaagattg ttgtgcggat
     1621 tcatattcgt ttgccctgac ggaacgattg ccgtctgaaa gcggtatctc gtagtcctct
     1681 aaagacggcg gactctcgcc gccaatgtcc caaaaatcga tggcagccgg ttttctcggc
     1741 ttacaccagc cggacaggga cgaacactca taccaacccg ccaactggca gcctgcaacc
     1801 gtaaatgcaa gcaacgcagc cattgccgta tattttattg cccgaatttc catcagcccc
     1861 ttttcccgaa aatcgcgctg ccgatacgga cgtgtgtcgc accgcactca atggcggcag
     1921 gcatatcgtc cgacatcccc atagacagca cgtctgcctt aacgccagcc gtattgaggt
     1981 cggcaagcag tttccgcatc gtttgaaatt gcaccttcaa ctccgtttca ctgctgttgg
     2041 ctttggcaac acacatcagt ccgcgtacga cgatattcgg cagcttcgcc acttccacag
     2101 caagcgcgac tgcttcttcg ggcgcgacac cgtgcttcac cgcctcgccc gcaatattca
     2161 cctcgataca cacctgcaag ggcggcattg aggaaggacg ctgttcgctc agccggacag
     2221 cggttttcag acggcatacg gtatgcaccc aatgcgcgcg ttcggcgaca aacttggttt
     2281 tgttggactg cacatcgccg atgacgtgcc acacgatgtc ggtcaaatcc gccaactctt
     2341 ccgttttgcc gtaccactcc tgaatatagt tctcgccgaa atcacgctgt ccggcggcgt
     2401 aaacttcgcg gatgccgtct gaagggaaag tcttaccgac ggcaatcagg ctgacggaat
     2461 gcggcttcct tcccgcctgc agaaccaatt ttccaatacg gtcggacacc tcccgataac
     2521 gttcttgcaa caccgtcata gattatcccc taattaaaaa tgattaaaca gttgaaaccc
     2581 ctccagtcag ggcggtacaa tcaaggttgt tagaaccatt ccaaccaatc gaaacattat
     2641 actaaacaga gccgcattat gcagattacc gacttactcg ccttcggcgc taaaaacaaa
     2701 gcatccgacc ttcacctgag ttcgggcata tcccctatga ttcgggttca cggcgatatg
     2761 cggcgcatca accttcccga aatgagcgcg gaagaggtcg gtaatatggt aacttcggtg
     2821 atgaacgacc accagcggaa aatctaccag caaaacttgg aagtcgactt ctcgttcgaa
     2881 ctgcccaacg tcgcccgatt ccgcgtcaac gccttcaaca ccggccgcgg tcccgccgcc
     2941 gtattccgca ccattcccag caccgtctta tcgctggaag aattgaaagc cccgagcatt
     3001 ttccaaaaaa tcgcagaatc gccgcgcggc atggtattgg ttaccggccc taccggttcg
     3061 ggcaaatcga ccacgcttgc cgcgatgatc aactacatca acgaaaccca gccggcacac
     3121 atcctgacca tcgaagaccc gatcgaattc gtccaccaaa gcaaaaaatc cctgattaac
     3181 cagcgcgagc tgcaccagca caccctcagc ttcgccaacg cgctgcgttc cgcattgcgc
     3241 gaagaccccg acgttatcct tgtcggcgag atgcgcgacc ccgaaaccat cggcttggca
     3301 ctgaccgccg ccgaaaccgg acacttggtt ttcggcacgc tgcacacgac cggcgcagca
     3361 aaaaccgtcg accgtatcgt ggacgtattc ccggcgggag aaaaagaaat ggtgcgctct
     3421 atgctgtccg aatcgctgac cgccgtcatc tcccaaaacc tgctgaaaac gcacgacggc
     3481 aacggccgtg tcgcctcgca cgaaatcctg attgccaacc ccgccgtccg caacctcatc
     3541 cgcgaaaaca aaatcacgca gattaactcc gtcctgcaaa ccgggcaggc gagcggtatg
     3601 cagacaatgg accaatcgct gcaatcgctg gtgcgccaag ggctgatcgc accggaagtc
     3661 gcacgcagac gcgcgcaaaa cagcgaaagt atgagtttct gacacacaac cgccttccgg
     3721 ccataccggc gggaaaacaa ggcgcaaaca cgcggggcgg gacgcagcat cccgcccggc
     3781 tacctttccg aacaagaagc gtccgccttc ctgttgaaac ctgccgccgc aaactgcaag
     3841 gcttaaaccg aaaagaagct aacgatgaat accgataacc tgcacgacat cttggacgaa
     3901 atggttcaag tgtattctca aaaaaaacaa agccgatccg aaaccccggc cgaaatcggc
     3961 gcacacttcc acccgctgct cgaccgcctg tgcgaaaccg cagaagcaca aaacgcgtcc
     4021 gacatcctta tcagcaaagg attcccgccc tcgttgaaaa tcaacagcgc attaaccccg
     4081 cagccgcaaa aggcgctgac aggcgaggaa accgccgcca tcgccgcatc gacgatgaac
     4141 gccgaacaat cggaaatatt ccggcgcgac ggcgaaatca actactccgt ccagtcgcgc
     4201 agcggcacgc gctaccgcgc caacgcctac cacagccaag gcagcgcagg tttggttttg
     4261 cggcgcatca accacgtcat cccgcaaatg caggaattgg gcctgcccga aaaactcaaa
     4321 gacctcgccg tcgcaccgcg cgggctgctg attatcgtcg ggcctaccgg ttcgggcaaa
     4381 tccaccacga tggcgactat gctcgaacac cgcaacaaaa ccctgcccag ccatatcgtt
     4441 accatcgaag acccgattga gtttatctac aaaccgcgcc gctgcatctt tacccagcgc
     4501 gaaatcggcg tcgacaccat aaactggcag acggcggtac aaaacgctat gcgccaatcc
     4561 cccgacgtgg tctgcatcgg cgaagtccgc agcagggaaa gtatggaata cgcgatgcag
     4621 ctcgcccaaa ccggccacct gtgcattttt acgctccacg ccaacaccgc gccgcagtcg
     4681 ctcgaacgca tactcaactt ctaccccaaa gaacagcaca accaaatact gatcgacatc
     4741 gccctcaacc tgaccggcat catctgccaa cgcctcgccc tcaaacaaga caaaacgggc
     4801 aggacggcgg ttgtcgactt gctcatcaac acgcccgcca tccaagactt catcctgaag
     4861 ggcgacctga tgaacatcag taaaatcatg gaaaccgcca aaaccgacgg aatgcagacg
     4921 atggatcaaa accttttcga actgtaccgt cacggcatca tcagttacga agaagccctg
     4981 cgccagtccg tttccgccaa caacctgcga ttgcacatcc aactgcacaa agaaggcaaa
     5041 acgcccgaac tcctttacga cagggtcaac ggtctcaacc tcatttcctg atccgcaaaa
     5101 cccaatgccg tctgaaaacc gcatccccgt tttcagacgg catgatttta tccgccccat
     5161 tcatgtgcta cactttatag tggattaaat ttatagtgga ttaacaaaaa tcaggacaag
     5221 gcgacgaagc cgcagacagc acaaatagta cggaaccgat tcacttggtg cttcagcacc
     5281 ttagagaatc gttctctttc agctaaggcg aggcaacgcc gtactggttt ttgttaatcc
     5341 actatattca cttcataaca ataaaccggt aaaaccatga aaaccccact cctcaagcct
     5401 ctgctcatta cctcgcttcc cgttttcgcc agtgttttta ccgccgcctc catcgtctgg
     5461 cagctaggcg aacccaagct cgccatgccc ttcgtactcg gcatcatcgc cggcggcctt
     5521 gtcgatttgg acaaccgcct gaccggacgg ctgaaaaaca tcatcgccac cgtcgccctg
     5581 tttaccctct cctcgctcac ggcacaaagt accctcggca cagggctgcc cttcatcctc
     5641 gccatgaccc tgatgacctt cggctttacc attttaggcg cggtcgggct gaaataccgc
     5701 accttcgcct tcggcgcact cgccgtcgcc acttacacca cacttaccta cacccccgaa
     5761 acctactggc tgaccaaccc cttcatgatt ttgtgcggca ccgtactgta cagcaccgcc
     5821 atcatcctgt tccaaatcat cctgccccac cgccccgtcc aagaaagcgt cgccaacgcc
     5881 tacgacgcac tcggtggcta cctcgaagcc aaagccgact tcttcgaccc cgatgaggca
     5941 gcctggatag gcaaccgcca catcgacctc gccatgagca acaccggcgt catcaccgcc
     6001 ttcaaccaat gccgttccgc cctgttttac cgccttcgcg gcaaacaccg ccacccgcgc
     6061 accgccaaaa tgctgcgcta ctacttcgcc gcccaagaca tacacgaacg tatcagctcc
     6121 gcccacgtcg actaccaaga gatgtccgaa aaattcaaaa acaccgacat catcttccgc
     6181 atccaccgcc tgctcgaaat gcagggacaa gcctgccgca acaccgccca agccctgcgc
     6241 gcaagcaaag actacgttta cagcaaacgc ctcggccgcg ccatcgaagg ctgccgccaa
     6301 tcgctgcgcc tcctttcaga cggcaacgac agtcccgaca tccgccacct gcgccgcctt
     6361 ctcgacaacc tcggcagcgt cgaccagcag ttccgccaac tccagcacaa cggcctgcag
     6421 gcagaaaacg accgcatggg cgacacccgc atcgccgccc tcgaaaccag cagcctcaaa
     6481 aacacctggc aggcaatccg tccgcagcta aacctcgaat caggcgtatt ccgccatgcc
     6541 gtccgcctgt ccctcgtcgt tgccgccgcc tgcaccatcg tcgaagccct caacctcaac
     6601 ctcggctact ggatactact gaccgccctt ttcgtctgcc agcccaacta caccgccacc
     6661 aaaagccgcg tccgccagcg catcgccggt accgtactcg gcgtaatcgt cggctcgctc
     6721 gtcccctact tcaccccgtc tgtcgaaacc aagctttgga tcgtcgtcgt cagcaccacc
     6781 ctgttcttca tgacccgcac ctacaaatac agcttctcga catttttcat caccattcag
     6841 gcactgacca gcctgtcgct tgcagggttg gacgtatatg ccgccatgcc cgtgcgcatc
     6901 atcgacacca ttatcggcgc atcccttgcc tgggcggcgg tcagctacct gtggcccgac
     6961 tggaaatacc tcacgctcga acgcaccgcc gcccttgccg tatgcagcaa cggtgcctat
     7021 ctcgaaaaaa tcaccgaacg cctcaaaagc ggcgaaaccg gcgacgacgt cgaataccgc
     7081 gccacccgcc gccgcgccca cgaacacacc gccgccctca gcagcaccct ttccgacatg
     7141 agcagcgaac ccgcaaaatt cgccgacagc ctgcaacccg gctttaccct gctcaaaacc
     7201 ggctacgccc tgaccggcta catctccgcc ctcggcgcat accgtagcga aatgcatgaa
     7261 gaatgcagcc ccgactttac ctcacagttc cacctcgccg ccgaacacac cgcccacatc
     7321 ttccaacacc tgcccgaaac cgaacccgac gactttcaga cagcactgga tacactgcgc
     7381 ggcgaactcg acaccctccg cacccacagc agcggaacac aaagccacat cctcctccaa
     7441 cagctccaac tcatcgcccg acagctcgaa ccctactacc gcgcctaccg ccaaattccg
     7501 cacaggcagc cccaaaatgc agcctgaaaa agtttcggca ttttgtaaga gagggcagat
     7561 tgtcagacag gttgcaagat agtggataag gctttgcgca gggtaaatgc gtagcaactg
     7621 aaccgtcatt cccacgaacc tacatcccgt cattcccacg aaaacagaaa accaaaaaca
     7681 gaaacctaaa atcccgtcat ttccacgaca atgggaatcc agttcgttcg gtttcgcttg
     7741 ttttaagttt cgggtaactt ccacttcgtc attcccgcgc aggcgggaat ccagtgcgt
//
LOCUS       DAXISH010000082         7339 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.082, whole genome shotgun sequence.
ACCESSION   DAXISH010000082 DAXISH010000000
VERSION     DAXISH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7339
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.082"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(610..1956)
                     /gene="mnmE"
                     /locus_tag="ACFOV4_001910"
     CDS             complement(610..1956)
                     /gene="mnmE"
                     /locus_tag="ACFOV4_001910"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFC7619859.1"
                     /translation="MSDNVPTIAAVATAPGRGGVGVIRISGKNLLPMAEALCGKTPKP
                     RVATYADFTDADGQAIDSGLLLFFAAPASFTGEDVIELQGHGGPVVMDMLLNRCLELG
                     ARLAEPGEFTKRAFLNDKLDLAQAEGVADLIDASSRSAARLALRSLKGDFSRRIHGLV
                     EDLITLRMLVEATLDFPEEDIDFLEAADARGKLDGLRRAVDDVLANAQQGAILREGLN
                     VVLVGAPNVGKSSLLNALAGDEVAIVTDIAGTTRDAVRERILIDGVPVHIVDTAGLRE
                     TDDVVERIGIERSRKAVSEADVALVLVDPREGVNDKTRAILDALPPELKRIEIHSKSD
                     LHAHAAGGFGTGAETVIALSAKTGDGLDALKRTLLREAGWQGEGEGLFLARTRHVNAL
                     KAAQEELSLAALCGNHQIELFAEHLRLAQVACGEITGEFTADDLLGVIFSRFCIGK"
     gene            2087..2242
                     /locus_tag="ACFOV4_001911"
     CDS             2087..2242
                     /locus_tag="ACFOV4_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619860.1"
                     /translation="MEKRNTYAFLLGIGSLLGLFHPAKTAIRPNPADDLKNIGGDFQR
                     AIEKARK"
     gene            2239..2670
                     /locus_tag="ACFOV4_001912"
     CDS             2239..2670
                     /locus_tag="ACFOV4_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2335 domain-containing protein"
                     /protein_id="HFC7619861.1"
                     /translation="MTENAQDKARQAVETVVKSPELVEQILSDEYVQIMIARRFHSGP
                     LPPPSDLAQYNDIISNGADRIMAMAEKEQAVRHETIRQDQTFNRRGQLYGFISVILIL
                     LFAVFLVWSGYPATAASLAGGTVVALAGAFVIGRSRDQGKN"
     gene            2804..7174
                     /gene="app"
                     /locus_tag="ACFOV4_001913"
     CDS             2804..7174
                     /gene="app"
                     /locus_tag="ACFOV4_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_168458961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesion and penetration autotransporter App"
                     /protein_id="HFC7619862.1"
                     /translation="MKTTDKRTTETHRKAPKTGRIRFSPAYLAICLSFGILPQAWAGH
                     TYFGINYQYYRDFAENKGKFAVGAKDIEVYNKKGELVGKSMTKAPMIDFSVVSRNGVA
                     ALVGDQYIVSVAHNGGYNNVDFGAEGSNPDQHRFTYKIVKRNNYKAGTNGHPYGGDYH
                     MPRLHKFVTDAEPVEMTSYMDGRKYIDQNNYPDRVRIGAGRQYWRSDEDEPNNRESSY
                     HIASAYSWLVGGNTFAQNGSGGGTVNLGSEKIKHSPYGFLPTGGSFGDSGSPMFIYDA
                     QKQKWLINGVLQTGNPYIGKSNGFQLVRKDWFYDEIFAGDTHSVFYEPRQNGKYSFHD
                     NNNGTGKIDAKHEHNSLPNRLKTRTVQLFNVSLSETAQEPVYHAAGGVNSYRPRLNNG
                     ENISFIDEGKGELILTSNINQGAGGLYFQGDFTVSPENNETWQGAGVHISEDSTVTWK
                     VNGVANDRLSKIGKGTLHVQAKGENQGSISVGDGKVILDQQADENNKKQAFSEIGLVS
                     GRGTVQLNADNQFNPDKLYFGFRGGRLDLNGHSLSFHRIQNTDEGAMIVNHNQDKEST
                     VTITGNKDIATTGNNNSLDSKKEIAYNGWFGEKDTTKTNGRLNLVYQPAAEDRTLLLS
                     GGTNLNGNITQTNGKLFFSGRPTPHAYNHLNDHWSQKEGIPRGEIVWDNDWINRTFKA
                     ENFQIKGGQAVVSRNVAKVKGDWHLSNHAQAVFGVAPHQSHTICTRSDWTGLTNCVEK
                     TITDDKVIASLTNTDISGNVSLADHAHLNLTGLATLNGNLSANGDTRYTVSHNATQNG
                     DLSLVGNAQATFNQATLNGNTSASGNASFNLSDHAVQNGSLTLSGNAKANVSHSALNG
                     NVSLADKAVFHFESSRFTGQISGSKDTALHLKDSEWTLPSGTELGNLNLDNATITLNS
                     AYRHDAAGAQTGSATDAPRRRSRRSLLSVTPPASAESHFNTLTVNGKLNGQGTFRFMS
                     ELFGYRSDKLKLAESSEGTYTLAVNNTGNEPASLEQLTVVEGKDNKPLSENLNFTLQN
                     EHVDAGAWRYQLIRKDGEFRLHNPVKEQELSDKLGKAEAKKQAGKDNAQSLDALIAAG
                     RDAVEKTESVAEPARQAGGENVGIMQAEEEKKRVQADKDSALAKQREAETQPATTAFP
                     RARRARRDLPQPQPQPQPQPQPQRDLISRYANSGLSEFSATLNSVFAVQDELDRVFAE
                     DRRNAVWTSGIRDTKHYRSQDFRAYRQQTDLRQIGMQKNLGSGRVGILFSHNRTENTF
                     DDGIGNSARLAHGAVFGQYGIGRFDIGISTGAGFSSGSLSDGIGSKIRRRVLHYGIQA
                     RYRAGFGGFGIEPHIGATRYFVQKADYRYENVNIATPGLAFNRYRAGIKADYSFKPAQ
                     HISITPYLSLSYTDAASGKVRTRVNTAVLAQDFGKTRSAEWGVNAEIKGFTLSLHAAA
                     AKGPQLEAQHSAGIKLGYRW"
BASE COUNT         1965 a         2071 c         1784 g         1519 t
ORIGIN      
        1 aggtctgtcg gcacggaaac ttatcgagaa aaacggtttc tttatagtgg attaacaaaa
       61 atcaggagaa agcgacgaag ccgcagacag tacggatagt gcggaaccga ctcactcggt
      121 gcttcagcac cttagagaat cgttctcttc gagctaagtc aaggcaacgc tgtactggtt
      181 tttgttaatc cactatagat tttacgtcct agattcccgc ctgcgcggga atgacgaatt
      241 tcaattttct gtttttgatt ttttgttttt acaggaatga cggtcttttc atatcgaaaa
      301 aagttgccgt accgcaccga taatttccgc ctgcgcggaa tgaagattca agcgttgccc
      361 gaaattcaaa aaaactatag tggattaaca aaaaccagta cggcgttgcc tcgccttagc
      421 tcaaagagaa cgattctcta aggtgctgaa gcaccaagtg aatcggttcc gtactatctg
      481 tactgtctgc ggcttcgttg ccttgtcctg atttttgtta atccactata aaaccaaacg
      541 gatcggattc ccgtttttat gggataacgg aatgttcagc cggacaccgc cacgatgctt
      601 tcgatccgtt tattttccga tacaaaacct cgaaaaaatc acgccgagca ggtcgtccgc
      661 cgtaaactcg cccgtgattt cgccgcatgc gacctgcgcc aagcgcaagt gttcggcaaa
      721 cagctcgatt tgatggttgc cgcacaatgc cgccagcgac aattcttcct gcgctgcttt
      781 gagtgcgttg acgtgccgcg tccgcgccaa aaacagccct tcgccctcgc cctgccatcc
      841 ggcctcgcgc aacaacgtcc gtttcagcgc gtccaagccg tcgccggttt tcgccgacag
      901 cgcgatgacg gtttccgcgc ccgtaccgaa cccgcctgcc gcgtgtgcgt gcaaatcgga
      961 tttgctgtgg atttcgatgc gtttcaactc cggcggcaac gcgtccaaaa tcgcccgtgt
     1021 cttgtcgttc acgccttcgc gcggatcgac caacaccagc gcgacatcgg cttcggatac
     1081 ggctttgcgg ctgcgttcga tgccgatgcg ttcgaccacg tcgtccgtct cgcgcaaacc
     1141 tgccgtatcg acaatatgca ccggaacgcc gtcaatcagg atacgttccc tgaccgcgtc
     1201 gcgcgtcgtt ccggcaatat cggtaacaat cgccacttcg tcgcccgcca gcgcgttcaa
     1261 caggctggat ttgccgacat tcggcgcgcc gaccaatacg acattcagac cttcgcgcaa
     1321 aatcgcgccc tgctgcgcgt tggcaagcac atcatccacg gcgcggcgca agccgtccag
     1381 tttgccgcgt gcgtctgccg cttcgagaaa atcaatgtct tcctcgggaa aatctaacgt
     1441 cgcttcgacc agcatccgca aggtaatcaa gtcttcgacc agaccgtgta tccgccgcga
     1501 aaaatcgcct ttgagcgagc gcaacgccag acgcgccgcc gaacggctgg atgcgtcaat
     1561 caaatccgcc acgccttccg cctgtgccaa gtccagtttg tcgtttaaaa acgcacgctt
     1621 cgtaaactcg cccggttcgg caaggcgcgc gcccaattcc aaacagcggt tcagcagcat
     1681 atccatcact accggcccgc cgtgtccctg aagctcgata acatcttcgc ccgtaaaact
     1741 tgccggtgcg gcaaaaaaaa gcaaaagccc gctgtcgatt gcctgaccgt ccgcgtccgt
     1801 aaaatcagca taggttgcca cgcgcggctt gggcgttttc ccacacaaag cctctgccat
     1861 cggcagcagg tttttccccg atatgcgtat cacgcccacg ccgccgcgcc cgggtgcggt
     1921 agcgactgcc gcaatcgttg gaacgttatc cgacataaaa cccccgaaaa ttcaaaacag
     1981 ccgcgattat agcaaatgcc gtctgaagtc cgacggtttg gctttcagac ggcataaaac
     2041 cgcaaaaatg cttgataaat ccgtccgcct gacctaatat aaccatatgg aaaaacgaaa
     2101 cacatacgcc ttcctgctcg gtataggctc gctgctgggt ctgttccatc ccgcaaaaac
     2161 cgccatccgc cccaatcccg ccgacgatct caaaaacatc ggcggcgatt ttcaacgcgc
     2221 catagagaaa gcgcgcaaat gaccgaaaac gcacaggaca aggcgcggca ggctgtcgaa
     2281 accgtcgtca aatccccgga gcttgtcgag caaatcctgt ccgacgagta cgtgcaaata
     2341 atgatagccc ggcgtttcca ttcgggaccg ttgccgccgc cgtccgactt ggcgcaatac
     2401 aacgacatta tcagcaacgg ggcagaccgc attatggcaa tggcggaaaa agaacaagcc
     2461 gtccggcacg aaaccatacg gcaagaccaa accttcaaca ggcgcgggca actgtacggc
     2521 ttcatcagcg tcatcctgat actgcttttt gccgtcttcc tcgtatggag cggctacccc
     2581 gcaaccgccg cctcccttgc cggcggcaca gtggttgcct tggcgggtgc tttcgtgatt
     2641 ggaagaagcc gagaccaagg caaaaattaa tgacaaatcc tagggcgtgc ttcatatccg
     2701 cccgaacgcc gaaccgcaca tataggcaca tcccgcgcgc cgcccggaag cggaagccgc
     2761 gccctcccaa acaaacccga atcccgtcag ataaggaaaa ataatgaaaa caaccgacaa
     2821 acggacaacc gaaacacacc gcaaagcccc gaaaaccggc cgcatccgct tctcgcctgc
     2881 ttacttagcc atatgcctgt cgttcggcat tcttccccaa gcttgggcgg gacacactta
     2941 tttcggcatc aactaccaat actatcgcga ctttgccgaa aataaaggca agtttgcagt
     3001 cggggcgaaa gatattgagg tttacaacaa aaaaggggag ttggtcggca aatcaatgac
     3061 aaaagccccg atgattgatt tttctgtggt gtcgcgtaac ggcgtggcgg cattggtggg
     3121 cgatcaatat attgtgagcg tggcacataa cggcggctat aacaacgttg attttggtgc
     3181 ggaaggaagc aatcccgatc aacatcgttt tacttataaa attgtgaaac ggaataatta
     3241 taaagcaggg actaacggcc atccttatgg cggcgattat catatgccgc gtttacataa
     3301 atttgtaacc gatgcagaac ctgttgaaat gaccagttat atggatgggc ggaaatatat
     3361 cgatcaaaat aattaccctg accgtgttcg tattggggca ggcaggcaat attggcgatc
     3421 tgatgaagat gagcccaata accgcgaaag ttcatatcat attgcaagtg cgtattcttg
     3481 gctcgttggt ggcaatacct ttgcacaaaa tggatcaggt ggtggcacag tcaacttagg
     3541 tagtgaaaaa attaaacata gcccatatgg ttttttacca acaggaggct catttggcga
     3601 cagtggctca ccaatgttta tctatgatgc ccaaaagcaa aagtggttaa ttaatggggt
     3661 attgcaaacg ggcaacccct atataggaaa aagcaatggc ttccagctgg ttcgtaaaga
     3721 ttggttctat gatgaaatct ttgctggaga tacccattca gtattctacg aaccacgtca
     3781 aaatgggaaa tactcttttc acgacaataa taatggcaca ggaaaaatcg acgccaaaca
     3841 tgaacacaat tctctgccta atagattaaa aacacgaacc gttcaattgt ttaatgtttc
     3901 tttatccgag acagcacaag aacctgttta tcatgctgca ggtggtgtca acagttatcg
     3961 acccagactg aataatggag aaaatatttc ctttattgac gaaggaaaag gcgaattgat
     4021 acttaccagt aacatcaacc aaggtgctgg aggattatat ttccaaggag attttacggt
     4081 ctcgcctgaa aacaacgaaa cgtggcaagg cgcgggcgtt catatcagtg aagacagtac
     4141 cgttacttgg aaagtcaatg gcgtggcaaa cgaccgcctg tccaaaatcg gcaaaggcac
     4201 gctgcacgtt caagccaaag gggaaaacca aggctcgatc agcgtgggcg acggtaaagt
     4261 tattttagat caacaagcag atgaaaataa taaaaaacaa gcctttagtg aaatcggctt
     4321 ggtcagcggc aggggtacgg tgcaactgaa tgccgataat cagttcaacc ccgacaaact
     4381 ctatttcggc tttcgcggcg gacgtttgga tttgaacggg cattcacttt cgttccaccg
     4441 tattcaaaat accgatgaag gggcgatgat tgtcaaccac aatcaagaca aagaatccac
     4501 cgttaccatt acaggcaata aagatattgc tacaaccggc aataacaaca gcttggatag
     4561 caaaaaagaa attgcctaca acggttggtt tggcgagaaa gatacgacca aaacgaacgg
     4621 gcggctcaac cttgtttacc agcccgctgc agaagaccgc accctgctgc tttccggcgg
     4681 aacaaattta aacggcaaca tcacgcaaac aaacggcaaa ctgtttttca gcggcagacc
     4741 aacaccgcac gcctacaatc atttaaacga ccattggtcg caaaaagagg gcattcctcg
     4801 cggggaaatc gtgtgggaca acgactggat caaccgcaca tttaaagcgg aaaacttcca
     4861 aattaaaggc ggacaggcgg tggtttcccg caatgttgcc aaagtgaaag gcgattggca
     4921 tttgagcaat cacgcccaag cagtttttgg tgtcgcaccg catcaaagcc acacaatctg
     4981 tacacgttcg gactggacgg gtctgacaaa ttgtgtcgaa aaaaccatta ccgacgataa
     5041 agtgattgct tcattgacca ataccgacat cagcggcaat gtcagccttg ccgatcacgc
     5101 tcatttaaat ctcacagggc ttgccacact caacggcaat cttagtgcaa atggcgatac
     5161 acgttataca gtcagccaca acgccaccca aaacggcgac cttagcctcg tgggcaatgc
     5221 ccaagcaaca tttaatcaag ccacattaaa cggcaacaca tcggcttcgg gcaatgcttc
     5281 atttaatcta agcgaccacg ccgtacaaaa cggcagtctg acgctttccg gcaacgctaa
     5341 ggcaaacgta agccattccg cactcaacgg taatgtctcc ctagccgata aggcagtatt
     5401 ccattttgaa agcagccgct ttaccggaca aatcagcggc agcaaggata cggcattaca
     5461 cttaaaagac agcgaatgga cgctgccgtc aggcacggaa ttaggcaatt taaaccttga
     5521 caacgccacc attacactca attccgccta tcgccacgat gcggcagggg cgcaaaccgg
     5581 cagtgcgaca gatgcgccgc gccgccgttc gcgccgttcc ctattatccg ttacacctcc
     5641 ggcttcggca gaatcccatt tcaacacgct gacggtaaac ggcaaattga acggtcaggg
     5701 aacattccgc tttatgtcgg aactcttcgg ctaccgcagc gacaaattga agctggcgga
     5761 aagttccgaa ggcacttaca ccttggctgt caacaatacc ggcaacgaac ctgcaagcct
     5821 cgaacaattg acggtagtgg aagggaaaga caacaaaccg ctgtccgaaa accttaattt
     5881 caccctgcaa aacgaacacg tcgatgccgg cgcgtggcgt taccaactca tccgcaaaga
     5941 cggcgagttc cgcctgcata atccggtcaa agaacaagag ctttccgaca aactcggcaa
     6001 ggcagaagcc aaaaaacagg cgggaaaaga caacgcgcaa agccttgacg cgctgattgc
     6061 ggccgggcgc gatgccgtcg aaaagacaga aagcgttgcc gaaccggccc ggcaggcagg
     6121 cggggaaaat gtcggcatta tgcaggcgga ggaagagaaa aaacgggtgc aggcggataa
     6181 agacagcgcc ttggcgaaac agcgcgaagc ggaaacccag ccggctacca ccgccttccc
     6241 ccgcgcccgc cgcgcccgcc gggatttgcc gcaaccgcag ccccaaccgc aacctcaacc
     6301 ccaaccgcag cgcgacctga tcagccgtta tgccaatagc ggtttgagtg aattttccgc
     6361 cacgctcaac agcgttttcg ccgtacagga cgaattggac cgcgtgtttg ccgaagaccg
     6421 ccgcaacgcc gtttggacaa gcggcatccg ggacaccaaa cactaccgtt cgcaagattt
     6481 ccgcgcctac cgccaacaaa ccgaccttcg ccaaatcggt atgcagaaaa acctcggcag
     6541 cgggcgcgtc ggcatcctgt tttcgcacaa ccggaccgaa aacaccttcg acgacggcat
     6601 cggcaactcg gcacggcttg cccacggcgc cgttttcggg caatacggca tcggcaggtt
     6661 cgacatcggc atcagcacgg gcgcgggttt tagcagcggc agtctttcag acggcatcgg
     6721 aagcaaaatc cgccgccgcg tgctgcatta cggcattcag gcacgatacc gcgccggttt
     6781 cggcggattc ggcatcgaac cgcacatcgg cgcaacgcgc tatttcgtcc aaaaagcgga
     6841 ttaccgctac gaaaacgtca atatcgccac ccccggcctt gcgttcaacc gctaccgcgc
     6901 gggcattaag gcagattatt cattcaaacc ggcgcaacac atttccatca cgccttattt
     6961 gagcctgtcc tataccgatg ccgcttcggg caaagtccga acgcgcgtca ataccgccgt
     7021 attggctcag gatttcggca aaacccgcag tgcggaatgg ggcgtaaacg ccgaaatcaa
     7081 aggtttcacg ctgtccctcc acgctgccgc cgccaaaggc ccgcaactgg aagcgcaaca
     7141 cagcgcgggc atcaaattag gctaccgctg gtaaccgccg gatatgccga aaggggtctg
     7201 acgatgccac cgtgcgctgt caaacccttt ttctgccgcc gccttgtgcc tgctccattg
     7261 tctgataacc gtcaaattga tttttagccc atgtttggtg ggtcggggaa atctatatct
     7321 tcgtccgtgc cgaaatagt
//
LOCUS       DAXISH010000083         7255 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.083, whole genome shotgun sequence.
ACCESSION   DAXISH010000083 DAXISH010000000
VERSION     DAXISH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7255
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.083"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            144..1154
                     /gene="dusB"
                     /locus_tag="ACFOV4_001914"
     CDS             144..1154
                     /gene="dusB"
                     /locus_tag="ACFOV4_001914"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFC7619863.1"
                     /translation="MHIGGYFIDNPIALAPMAGITDKPFRRLCRAFGAGWAVCEMLTS
                     DPTLRNTRKTLHRSDFTDEGGIVAVQIAGSDPQQMADAARYNVSLGAQLIDINMGCPA
                     KKVCNVQAGSALMQNEPLVAAILEAVVKAAGVPVTLKTRLGWHDDHQNLPVIAKIAED
                     CGIAALAVHGRTRTQMYKGEARYELIAETKCRLNIPVWVNGDITSPQKAQAVLKQTAA
                     DGIMIGRGAQGRPWFFRDLKHYAEHGVLPPALSLAECTATILNHIRAMHAFYGDTAGV
                     RIARKHIGWYIGEMPDGEQIRREINRLDSAAAQYDTLAGYLERLAEKTDGWACAYRPN
                     AV"
     gene            1185..1424
                     /locus_tag="ACFOV4_001915"
     CDS             1185..1424
                     /locus_tag="ACFOV4_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HFC7619864.1"
                     /translation="MPHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLL
                     VCVMEQCGGNQSKASVMLGLNRNTLRKKLIQHGLL"
     gene            1427..1963
                     /gene="ruvC"
                     /locus_tag="ACFOV4_001916"
     CDS             1427..1963
                     /gene="ruvC"
                     /locus_tag="ACFOV4_001916"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFC7619865.1"
                     /translation="MSATVRILGIDPGSRVTGFGIIDVRGRDHFYVASGCIKTPPDAP
                     LADRIAVIVRHIGEVVAVYKPQQAAVEQVFVNVNPASTLMLGQARGAALAALVSHKLP
                     VSEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRNHG
                     LAAKLNPSGMQVKRGRFQ"
     gene            2014..2900
                     /locus_tag="ACFOV4_001917"
                     /pseudo
     CDS             2014..2900
                     /locus_tag="ACFOV4_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243640.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A biosynthesis lauroyl acyltransferase"
     gene            3368..3502
                     /locus_tag="ACFOV4_001918"
     CDS             3368..3502
                     /locus_tag="ACFOV4_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619866.1"
                     /translation="MPSERIFRSILRLVGVSSETVKQKFAGVELSYAGKAAGESLYCL
                     "
     gene            3619..4413
                     /locus_tag="ACFOV4_001919"
     CDS             3619..4413
                     /locus_tag="ACFOV4_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFC7619867.1"
                     /translation="MNTILAFDIETVPDVQGIRTLYELPSSLPDDEVVLFAQQKRRAQ
                     TGGDFMQHHLHQVVAISCCMRWGQDKIHIGTIGEADDGEEVVIAKFFELVEKHTPQLV
                     SWNGGGFDLPVLHYRSLIYGINAARYWDMGDGDFGDSRDFKWNNYISRYHQRHCDLMD
                     LLALYQPRANVPLDDMAKLCGFPGKLGMDGSKVWEAFHTGRLKEIRNYCETDAANTYL
                     MYLRFCLVSGRLDADEYEMEIKRMRNYLSAQVGEKPHWEEFVRAWE"
     gene            4417..4548
                     /locus_tag="ACFOV4_001920"
     CDS             4417..4548
                     /locus_tag="ACFOV4_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009345188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619868.1"
                     /translation="MKFKPVVRRCARAAVAASDGIRGMRPCRLKPFPVKPNNIERKK"
     gene            4545..7148
                     /gene="pepN"
                     /locus_tag="ACFOV4_001921"
     CDS             4545..7148
                     /gene="pepN"
                     /locus_tag="ACFOV4_001921"
                     /EC_number="3.4.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HFC7619869.1"
                     /translation="MSKTVRYLKDYQTPAYRILETDLHFDIAEPQTVVKSRLTVEPQR
                     VGEPLVLDGSAKLLSVKINGAAADYVLEGETLTIAGVPSERFTVEVETEILPVENKSL
                     MGLYASGGNLFTQCEPEGFRKITFYIDRPDVMSKFTTTIVADKKRYPVLLSNGNKIDG
                     GEYSGGRHWVKWEDPFAKPSYLFALVAGDLAVTEDRFTTMGGRNVKIEFYTTEADKPK
                     VGFAVESLKNAMKWDETRFGLEYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADS
                     RTATDTDFEGIESVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRA
                     VRRIENIRLLRQHQFPEDAGPTAHPVRPARYEEMNNFYTMTVYEKGAEVVRMYHTLLG
                     EEGFQKGMKLYFQRHDGQAVTCDDFRVAMADANGINLDQFALWYSQAGTPVLDAQGRL
                     KDGAFELTIKQTVPPTPDMADKQPMMIPVKIGLLNRNGEAAAFDYQGKRATEAVLLLT
                     EAEQTFPLEGVTEAVVPSLLRGFSAPVHLNYPYSDDDLLLLLAHDSDAFTRWEAAQTL
                     YRRAVAANLAALSDGIELPKHEKLLAAVEKVISDDLLDNAFKALLLGVPSEAELWDGA
                     ENIDPLRYHQAREALLDTLAVRFLPKWHELNRQAAKQENQSYEYSPEAAGWRTLRNVC
                     RAFVLRADPAHIETVAEKYGEMAQNMTHEWGILSAVNGNESDTRNRLLAQFADKFSDD
                     ALVMDKYFALVGLSRRSDTLQQVQTALQHPKFSLENPNKARSLIGSFSRNVPHFHAED
                     GSGYRFIADKVIEIDRFNPQVAARLVQAFNLCNKLEPHRKNLVKQELQRIRAQEGLSK
                     DVGEIVGKILD"
BASE COUNT         1812 a         1915 c         1931 g         1597 t
ORIGIN      
        1 ccgcctgtga gtggcggggc agggaatctg tgtgcggatt atgccataaa acggtgtccg
       61 ccccaatcgc gggcgcgtcc ggagattgga aatcctgctt aaaaaatgta caatggcgta
      121 cttttttgaa acgcggatcc attatgcaca tcggcggcta ttttatcgac aaccccatcg
      181 cacttgcacc gatggcaggc attaccgaca agccgttccg tcgcctttgc cgggcgtttg
      241 gcgcaggttg ggcggtgtgc gaaatgctga ccagcgaccc gacgcttaga aataccagaa
      301 aaaccctgca ccgcagcgat tttaccgatg aaggcggcat cgttgccgtg cagattgccg
      361 gcagcgatcc gcagcagatg gcggatgcgg cgcgttacaa cgtcagcctt ggggcgcagc
      421 ttatcgacat caatatgggc tgtcccgcca agaaagtctg caatgtccaa gccggtagcg
      481 cgctgatgca gaacgagccg ctggttgccg ccattttgga agcggtggtc aaggcggcgg
      541 gcgttcccgt taccctcaaa acccgtttgg gttggcacga cgaccatcaa aacctgcccg
      601 tcatcgccaa aatcgccgaa gattgcggca tcgccgccct tgccgtccac ggacgcacgc
      661 gcacacaaat gtacaaaggc gaagcacgtt acgaactcat cgccgaaacc aaatgccgtc
      721 tgaacatccc ggtctgggtc aacggcgaca ttacctcgcc gcaaaaagcc caagccgtcc
      781 tcaaacaaac cgccgcagac ggcatcatga tagggcgcgg tgcgcaaggc aggccgtggt
      841 tcttccgcga tttgaaacat tatgccgaac acggtgtttt gccgcctgcc ttgagtttgg
      901 cagaatgcac cgccactatt ttgaaccaca tccgagccat gcacgcgttt tacggcgaca
      961 ccgccggtgt gcgcatcgca cgcaaacaca taggctggta catcggcgag atgcccgacg
     1021 gcgagcagat acgccgtgaa atcaaccgct tggacagtgc ggcggcgcaa tacgacacac
     1081 ttgccggtta tcttgaaaga cttgccgaaa aaaccgacgg ttgggcgtgc gcctaccgcc
     1141 caaatgccgt ctgaacaccc gattatcctt ttgaaagcgc gattatgccc catacccttc
     1201 ccgatatttc ccaatgtatc agacaaaatt tagaacaata tttcaaagac ctgaacggta
     1261 ccgaaccttg cggcgtgtac gatatggtat tgcatcaggt ggaaaagccg ctgctggtgt
     1321 gcgtgatgga gcaatgcggc ggtaatcagt ccaaagcctc cgtcatgttg ggactgaacc
     1381 gcaatacctt gcgtaaaaaa ctgattcaac acggtttgct gtgaatatgt cggcaaccgt
     1441 ccgtatctta ggtatcgacc cgggcagccg cgtaacgggt ttcggcatca tcgatgtcag
     1501 ggggcgcgat catttttacg tcgcctccgg ctgcatcaaa acgcctcccg atgcgcctct
     1561 ggcagacagg attgccgtga ttgtgcggca catcggcgaa gtcgttgccg tttacaagcc
     1621 gcagcaggcg gcggtggaac aggtgttcgt caacgtcaat ccggcatcga cgctgatgct
     1681 gggtcaggct aggggcgcgg cattggcggc attggtcagc cataagctgc ccgtttcgga
     1741 atacacggcc ttgcaggtca aacaggcggt agtcggcaaa ggcaaggcgg cgaaagaaca
     1801 ggtgcagcat atggtggtgc agatgctggg gctttcggga acgccgcagg cggatgcggc
     1861 ggacggtctt gccgtcgcgc tgacccacgc cttacgcaac cacgggcttg ccgccaaact
     1921 caatccttcg gggatgcagg tcaagcgcgg caggtttcaa tagtttcaga cggcatttgt
     1981 attttgccgt ctgaaaagaa aatgtgtatc gagatgaaat ttatattttt tgtactgtat
     2041 gttttgcagt ttctgccgtt tgcgctgctg cacaaacttg ccgacctgac gggtttgctc
     2101 gcctaccttt tggtcaaacc ccgccgccgt atcggcgaaa tcaatttggc aaaatgcttt
     2161 cccgagtggg acggaaaaaa gcgcgaaacc gtattgaagc agcatttcaa acatatggcg
     2221 aaactgatgc ttgaatacgg cttatattgg tatgcgcctg ccaaacgcct gaaatcgctg
     2281 gtgcgttacc gcaataagca ttatttggac gacgcgctgg cggcagggga aaaagtcatc
     2341 atcctgtatc cgcactttac cgcgttcgag atggcggtgt acgcgcttaa tcaggatgtc
     2401 ccgctaatta gtatgtattc ccaccaaaaa acaagatatt ggacgcacag attttgaaag
     2461 gccgcaaccg ctacgacaac gtcttcctca tcgggcgcac cgaagggctg cgcgccctcg
     2521 tcaaacagtt ccgcaaaagc agcgcgccgt ttctgtatct gcccgatcag gatttcggac
     2581 gcaacgattc ggtttttgtg gattttttcg ggattcagac ggcaacgatt accggcttga
     2641 gccgcattgc cgcgcttgca aatgccaaag tgattcccgc catccccgtc agggaggcgg
     2701 acaatacggt tacactgcat ttctacccgg cttggaaatc ctttccgggt gaagacgcgc
     2761 aggccgacgc gcagcgtatg aaccgcttta tcgaagagcg ggtgcgcgaa catcccgagc
     2821 agtatttttg gctgcacaag cgttttaaaa cccgtccgga aggtgtacag gatttttaca
     2881 aattacacga aactacatag tggactatta agggaaaatt gagttttgct taaatgcgaa
     2941 aaattgaatt atataaacag aagcatttaa taattgctgt tattttaagt gtctaaaaaa
     3001 taatattttt tgattttaaa aatagatttc aaagaaaatt tggagaatac atgataaatc
     3061 aatgaatata ttctattgat atggttaata tattaaaatt attttccttt aaaaacataa
     3121 tattataaat tattattcaa taactgctat tttattcggt gccagcttga gaaatatatt
     3181 gtcaaatata tagacattat aaaattaagt atcaatttaa ataaattttt agaattttaa
     3241 tctaaaaaat caaaaaattc actattttat aaaataaacg cttctatatt cgttttgtaa
     3301 aaaatgcttg gcaagctgta aaaaatggcg tacatttcgc tacatgtaat tacacaacag
     3361 gcaggaaatg ccgtctgaaa ggattttccg gtcaatcttg cgattggtcg gggtttcatc
     3421 ggaaacggtg aaacaaaagt ttgccggcgt agagttgagc tacgcgggca aagccgcagg
     3481 cgaaagcctg tattgtttgt gaagcgtaaa tctctgattt gaggtattgg ggcaatcctg
     3541 tggggggttg cctctttttt tatccgcctt ttaatgacac aataggcgca agtctgtttt
     3601 tgaatgcaag gtactgccat gaatacgatt ttggctttcg atattgaaac cgtacctgat
     3661 gtccaaggta tccgaacatt gtacgagctg ccgtcctcgc tgcccgacga cgaagtggtg
     3721 ctgtttgccc agcaaaaacg ccgcgcccaa acgggcggcg attttatgca gcatcatctt
     3781 catcaggttg tggcgatttc gtgctgcatg cgttgggggc aggacaaaat ccatatcggc
     3841 acaatcggcg aggcggacga cggcgaggaa gtggttatcg ccaaattttt cgagttggtg
     3901 gaaaaacata cgccgcaatt ggtcagttgg aacggcggcg gtttcgacct gcccgtactg
     3961 cattaccgct ccctgatata cggcatcaac gccgcgcgct attgggatat gggcgacggc
     4021 gatttcggcg atagccgcga tttcaagtgg aacaactaca tcagccgtta ccaccaacgc
     4081 cactgcgatt tgatggattt gctcgcactt tatcagccga gggcaaacgt gccgctggac
     4141 gatatggcga aactgtgcgg ttttccgggc aagctgggta tggacggcag caaggtttgg
     4201 gaggcattcc atacgggcag gctgaaggaa atccgcaatt attgcgaaac cgacgcggca
     4261 aacacttatc tgatgtacct gcgtttctgt ctggtcagcg gcaggctgga tgcggacgaa
     4321 tacgaaatgg aaatcaaacg gatgcggaat tacctgtccg cacaagtcgg ggaaaagccg
     4381 cattgggaag agtttgtccg cgcgtgggaa taaagattga aattcaaacc ggttgtccgg
     4441 cggtgcgccc gtgccgccgt tgcggcttca gacggcatac gcgggatgcg cccatgccgt
     4501 ctgaagcctt ttccagtcaa accaaacaat attgaaagaa aaaaatgagc aaaaccgtcc
     4561 gttatctgaa agattaccaa acgcctgcct accgcattct cgaaaccgac ctgcattttg
     4621 atattgccga accgcaaacc gtcgtgaagt cgcgtttgac ggttgagccg cagagggtag
     4681 gggagccgct ggtgttggac ggttcggcga aacttttgtc cgtcaaaatt aacggggcgg
     4741 cggcggatta tgtgttggaa ggcgagacgc tgacgattgc aggcgtgcca tccgaacgct
     4801 tcaccgttga agtggaaacc gaaatcctgc cggtggaaaa caaatcgctg atggggctgt
     4861 atgcttccgg cggcaatcta tttacccagt gcgagccgga gggcttccgc aaaatcacgt
     4921 tctacatcga ccgtccggat gtgatgtcca aattcacaac caccatcgtt gcggacaaaa
     4981 aacgctatcc cgttttgctt tccaacggca acaaaatcga cggcggcgag tattcaggcg
     5041 gccgccattg ggtgaaatgg gaagacccgt ttgccaaacc gagctatctg tttgctttgg
     5101 tcgcgggcga tttggcggtc acggaagacc gtttcaccac catgggcggc agaaacgtca
     5161 aaatcgagtt ttacaccacc gaagcggaca agcccaaggt cggctttgcc gtggaatcgc
     5221 tgaaaaacgc gatgaaatgg gacgaaacgc gcttcggttt ggaatacgac ttggatattt
     5281 tcatggtcgt cgccgtaggc gatttcaata tgggtgcgat ggaaaacaag ggtttgaaca
     5341 tctttaacac caagttcgtc cttgccgaca gccgcaccgc caccgatacc gatttcgaag
     5401 gaatcgaatc cgtgatcgga cacgaatatt tccacaactg gacgggcaac cgcgtaacct
     5461 gccgcgactg gttccagctt tcgctgaagg aagggttgac cgtgttccgc gaccaagaat
     5521 tttccggcga ccgcgccagc cgcgccgtgc gccgtatcga aaacatccgc ctgctgcgcc
     5581 agcaccagtt ccccgaagac gcaggtccga ccgcacatcc ggtgcgcccc gcccgatatg
     5641 aggagatgaa caatttttac accatgaccg tttatgaaaa aggcgcggaa gtggtgcgga
     5701 tgtatcacac cttgctcggc gaagagggct tccaaaaagg tatgaagctc tatttccaac
     5761 gccacgacgg acaggctgtt acctgcgacg atttccgcgt ggcgatggcg gacgcgaacg
     5821 gcatcaatct cgaccagttc gccttgtggt acagccaggc gggtacgccg gttttagatg
     5881 ctcaaggccg tctgaaagat ggagcgtttg aattgaccat taaacaaacc gtgccgccca
     5941 cgcccgatat ggcggacaaa cagccgatga tgattcccgt caaaatcggg ctgctgaacc
     6001 gcaacggtga agcggcggca ttcgattatc agggcaaacg cgcgaccgaa gccgtattgc
     6061 tgctgaccga agccgaacag accttcccgc tcgaaggtgt aaccgaagcc gtcgttccct
     6121 cgctgctgcg cgggttcagt gcgccggtgc atctgaacta tccgtacagc gacgacgacc
     6181 tgctgctcct gcttgcccac gacagcgacg ctttcacgcg ctgggaagcc gcccaaacgc
     6241 tctaccgccg cgccgtcgcc gccaaccttg ccgcgctttc agacggcatc gagttgccga
     6301 aacacgaaaa actgcttgcc gccgtcgaaa aagtcatttc agacgacctc ttggacaacg
     6361 ccttcaaagc cctgcttttg ggtgtgccgt ctgaagccga actgtgggac ggcgcagaaa
     6421 acatcgaccc gctgcgctac catcaggcgc gcgaagcctt gttggatacg cttgccgtcc
     6481 gcttcctgcc gaaatggcac gaattgaacc gtcaggcggc gaagcaggaa aaccaaagct
     6541 acgagtacag ccccgaagct gccggctggc gcacgctgcg caacgtctgc cgcgccttcg
     6601 tcctgcgcgc cgaccccgcg cacatcgaaa ccgttgccga aaaatacggc gaaatggcgc
     6661 aaaacatgac ccacgaatgg ggcatcctgt ccgccgtcaa cggcaacgaa agcgatacgc
     6721 gcaaccgcct gctggctcag tttgccgaca agttttcaga cgacgcgctg gtgatggaca
     6781 aatatttcgc cctcgtcggc ttaagccgcc gcagcgacac cctgcaacag gtccaaaccg
     6841 ccttgcagca tccgaaattc agcctcgaaa accccaacaa agcccgttcg ctcatcggca
     6901 gcttcagccg caacgtcccg catttccacg cagaagatgg cagcggctac cgcttcatcg
     6961 ccgacaaagt catcgaaatc gaccgcttta acccgcaggt cgccgcccgt ttggtgcaag
     7021 cgttcaacct ctgcaacaag ctcgagccgc accgcaaaaa cttggtgaaa caggaattgc
     7081 agcgcattcg ggcgcaggaa ggattgtcga aagacgtggg cgaaatcgtc ggcaaaattt
     7141 tggattgagg ccgtcaaaca gaaaaacaat gccgtctgat atagttacac acacgtttta
     7201 tcatcacttc cccatcgttt tattacgcaa tggcaaaacg gccgcaaagt catat
//
LOCUS       DAXISH010000084         7145 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.084, whole genome shotgun sequence.
ACCESSION   DAXISH010000084 DAXISH010000000
VERSION     DAXISH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7145
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.084"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(141..728)
                     /locus_tag="ACFOV4_001922"
     CDS             complement(141..728)
                     /locus_tag="ACFOV4_001922"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFC7619870.1"
                     /translation="MEHKLPQLPYELDALSPHLSKETLEFHYGKHHQTYITNLNNQIK
                     GTEFENLPLEEIVKKSSGGVFNNAAQTWNHTFYWLGFTPKGQGKPSGELAAAIDAKWG
                     SFEKFQEAFNACAAGTFGSGWAWLVKTPAGGLDLVSTSNAATPLTTENTPLLTCDVWE
                     HAYYIDYRNSRPNYLKGFWEIVNWDEVAKRFAALS"
     gene            891..2297
                     /gene="dnaB"
                     /locus_tag="ACFOV4_001923"
     CDS             891..2297
                     /gene="dnaB"
                     /locus_tag="ACFOV4_001923"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFC7619871.1"
                     /translation="MNDYTAMPSEDREVGALSLPPHSMEAEQSVLGGLMLENPAWDRI
                     ADVVSGEDFYRHEHRLIFRSIAKLINESRPADVITVQEDLQRNEELEAAGGFEYLITL
                     AQNTPSAANIRRYAEIVRERSIMRQLAEVGTEIARSAYNPQGRDAGQLLDEAENKVFQ
                     IAESTAKSKQGFLEMPDLLKEVVQRIDMLYSRDNPDEVTGVPTGFIDLDKKTSGLQPG
                     DLIIVAGRPSMGKTAFSINIAEHVAVEGKLPVAVFSMEMGGAQLVMRMLGSVGRLDQS
                     VLKTGRLEDEHWGRLNEAVVKLSDAPVYIDETPGLTALELRARARRLARQFNNKLGLI
                     VIDYLQLMAGSGRSDNRASELGEISRSLKALAKELQVPIIALSQLSRTVESRTDKRPM
                     MSDLRESGAIEQDADLIMFMYRDEYYNQDSPMKGLAECIIGKHRNGPVGKIFLTWTGQ
                     FTKFDNAAYIPEEAKIED"
     gene            2599..3267
                     /locus_tag="ACFOV4_001924"
     CDS             2599..3267
                     /locus_tag="ACFOV4_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspH/FimT family pseudopilin"
                     /protein_id="HFC7619872.1"
                     /translation="MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASH
                     AERIANLLRFSRGEAVRLNLPVYICPVQVKKGGAPNNKCDFGKKGQGMLAFGDKNGNK
                     TYDGDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYST
                     NQDLTNTSRFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTV
                     CQYK"
     gene            3297..3905
                     /gene="pilV"
                     /locus_tag="ACFOV4_001925"
     CDS             3297..3905
                     /gene="pilV"
                     /locus_tag="ACFOV4_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus modification protein PilV"
                     /protein_id="HFC7619873.1"
                     /translation="MKNNDCFRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVA
                     SVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKNYNLYMGNNTLSAVDGEFAIDAI
                     KTKTQLAEAQLKRFSYELKNALPDAAAIHYAVCKDSSGNAPTFSGNAFSSNCDNKANG
                     DTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGRE"
     gene            3902..4855
                     /locus_tag="ACFOV4_001926"
     CDS             3902..4855
                     /locus_tag="ACFOV4_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilW family protein"
                     /protein_id="HFC7619874.1"
                     /translation="MRRKMLNVPKGSYDGMKGFTIIEFLVAGMLSMIVLMAVGSSYFT
                     SRKLNDAANERLAIQQDLRNAATLIVRDARMAGSFGCFNMSEHIEQDVVSDVTQKDSL
                     FSLKRNSTRNSTNKLIPIAESSNIGYQGFIQRLNALIFQYGIDDVNASADTTVVSSCA
                     AISKPGKQILNLEDVKKELKIVSQDKERNGNIARQRHVVNAYAVGRIAGEEGLFRFQL
                     NEKGEWGNPQLLVKKINKMDIRYIYVSGCPEDDDAGKEETFRYTDKFNSAQDAVTPAG
                     VEVLLSSGTDTKIAASSDNHIYAYRIDATIRGGNVCANRTL"
     gene            4834..5427
                     /locus_tag="ACFOV4_001927"
     CDS             4834..5427
                     /locus_tag="ACFOV4_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilX N-terminal domain-containing pilus assembly
                     protein"
                     /protein_id="HFC7619875.1"
                     /translation="MRKQNTLTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNT
                     EQRISANESDRKLALSLAEAALREGELQVLDLEYDTDSKVTFSENCGKGLCTAVNVRT
                     NNDNEEAFDNIVVQGKPTVEAVKRSCPANSTNLCIDNKGTKYKKGTQSVSKMPRYIIE
                     YLGVKNGENVYRVTAKAWGKNANTVVVLQSYVSNNDE"
     gene            5432..5905
                     /locus_tag="ACFOV4_001928"
     CDS             5432..5905
                     /locus_tag="ACFOV4_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilX family type IV pilin"
                     /protein_id="HFC7619876.1"
                     /translation="MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTE
                     MVGINNISKQFILKNPLDDNQTIKSKLEIFVSGYKMNPKIAEKYNVSVHFVNKEKPRA
                     YSLVGVPKTGTGYTLSVWMNSVGDGYKCRDAASAQAHLETLSSDAGCEAFSNRKK"
BASE COUNT         1945 a         1618 c         1807 g         1775 t
ORIGIN      
        1 tgacagtaac cgtagcaact gaaccgtcat tcccacggaa gtgggaatct agaaataaaa
       61 agcagcaggc atttatcgga aataactgaa attcaatacc gcaaaaatct acccgaaatg
      121 atatagcgga ttaacaaaaa tcaggacaag gcggcaaaac gtttggcgac ttcgtcccag
      181 ttgacgattt cccagaaacc tttcaggtag ttaggacggc tgttgcggta gtcgatgtag
      241 taggcgtgtt cccacacgtc gcaggtcagc agcggcgtgt tttcagtggt cagcggcgta
      301 gcggcgttgg aagtggaaac caaatccaat ccgccggcag gggtttttac cagccacgcc
      361 caaccggagc cgaaagtacc ggccgcgcag gcattgaacg cttcttggaa tttctcgaag
      421 ctgccccatt tcgcgtcgat ggcggcggcc agttcgccgg aaggtttgcc ttgacctttg
      481 ggcgtgaaac ccagccagta gaaagtgtgg ttccaagttt gggctgcgtt gttgaacacg
      541 ccgcccgaag attttttcac aatctcttcc aaaggcaggt tttcaaattc ggtgcctttg
      601 atttgattgt tcaggttggt gatgtaggtt tgatggtgtt tgccgtagtg gaattccaaa
      661 gtttctttgc tcagatgcgg ggacaatgcg tccagttcat aaggcagttg cggcagctta
      721 tgttccattt tgtgctccta atattgtttt aaatgttgta ttttggcagt gttgctgcaa
      781 atagctcagc agcgcacata ttttacctgt tttgagggat ggaaaccaat taaacctgct
      841 ttacgctata atagaaggtt gcaatttcgg cacgacagat aggatgtacc atgaacgatt
      901 acacagctat gccgtctgaa gaccgtgagg tcggcgcatt gtcgctgcct ccacattcga
      961 tggaggcgga acaatccgtt ttgggcggtt tgatgctgga aaatccggct tgggacagga
     1021 ttgccgatgt ggtttccggt gaagacttct accgccacga acaccgcctg attttccgat
     1081 ccattgctaa attaatcaat gagagccgtc ccgccgatgt gattacggtt caggaagatt
     1141 tgcagcggaa cgaagaattg gaagcggcag gcggattcga atatctgatt acgctggcgc
     1201 aaaacacccc gtctgccgcc aacatccgcc gctacgccga aatcgtgcgc gagcgttcca
     1261 tcatgcgcca actcgccgaa gtggggacgg aaatcgcccg cagcgcatac aatccgcaag
     1321 gcagggacgc ggggcagctt ttggacgagg cggaaaacaa agtattccaa atcgccgaaa
     1381 gcaccgccaa atccaagcag ggctttttgg agatgcccga tttgctgaaa gaagtcgtac
     1441 agcgcatcga tatgctctac tcgcgcgaca atcccgatga agttaccggc gtgccgacag
     1501 ggttcatcga cctcgacaaa aaaacctcgg gtctgcaacc cggcgacctg attatcgttg
     1561 ccggtcgtcc gtctatgggt aagaccgcct tttctatcaa tatcgccgaa cacgttgccg
     1621 tagaaggcaa gctgccggtt gccgtcttct caatggaaat gggcggggcg caactggtca
     1681 tgcgtatgct cggctcggtc ggacggttgg atcaaagcgt tttgaaaacc ggcaggctcg
     1741 aagacgaaca ctggggtcgc ctgaacgaag cagtcgtcaa actctccgac gcgcccgtgt
     1801 acatcgacga gaccccgggt ctgaccgcgc tcgaactgcg cgcccgtgcc cgccgtctcg
     1861 cccgtcaatt taacaataag cttggattga ttgtcatcga ctacctgcaa ctgatggcag
     1921 gatccggccg ttccgacaac cgagcttcgg agctgggaga gatttcacgt tcgctcaaag
     1981 cgttggcgaa agaattgcaa gtccccatca tcgccctgtc gcaattgagc cgcacggtcg
     2041 aatcgcgtac cgacaaacgc ccgatgatgt ccgaccttcg cgaatccggt gctatcgagc
     2101 aggatgccga cctgattatg tttatgtacc gcgacgaata ctacaaccaa gactcgccca
     2161 tgaaaggcct tgccgaatgt atcatcggca aacaccgcaa cggtcccgtc ggtaaaatct
     2221 tcctcacatg gacgggacaa ttcaccaaat tcgacaatgc tgcctatatt cccgaggagg
     2281 caaagataga ggattaaatg gctatataaa aatttattag gcgaaatcag gcaaaatcgt
     2341 ttaaaatcat gcttagagat tgccctaaaa aataaaacgc ggtcttgagg catttttgca
     2401 ttcagcccgc atataattga aaatatagtg gattaacaaa aatcaggaca aggcaacgaa
     2461 gccgcagacc gtacaaatag tacggaaccg attcacttgg tgcttgagca ccttagagaa
     2521 tcgttctctt tgagctaagg cgaggcaacg ccgtactggt ttgaatttaa tccacgatac
     2581 attaccagtt aacgtcctat gtgtacacga aaacaacaag gtttcacgct aacagagctg
     2641 ctcatcgtga tggtcattgc agccattatg gcgatgatag ccctccccaa tatgagccaa
     2701 tggattgcat cccgccgcat tgccagtcat gcggagcgga ttgccaacct tttgcgtttc
     2761 tccaggggag aagccgtccg gctcaatctt cctgtctata tctgtcctgt tcaagttaaa
     2821 aaaggcggtg cgcccaacaa taaatgtgac ttcggcaaga aggggcaggg aatgttggct
     2881 tttggcgata agaatggcaa taagacatat gacggcgata cggcggatgt tctccttcgc
     2941 agtgtggtat tgaatgatga tatcaatgat aagcggatta attatgcctt taaccatatc
     3001 gctttcggtc aaacgcagcc gaccgctgac cgtgtagttt ggacattcaa tcaaaacggg
     3061 acgttcggtt attctaccaa tcaggatctc acgaatactt ccagatttgt ttactccgac
     3121 ggttatatcc aaatcgtgct gacagatgcg agagcagttt cagatgccga taagaaattc
     3181 cgttcggcgg tggttttgat taacagcagc ggcagggttg aggtttgtcc tagaaacgat
     3241 aggcgtaccg tatgccaata taaatgattg ttttagtcgg tttgggaaat aaaaaaatga
     3301 agaataatga ttgcttccgc ctgaaaaacc cccagtccgg tatggcgctg atagaagtct
     3361 tggttgctat gctcgttctg accatcggta ttttggcgtt actgtctgtg cagttgcgga
     3421 cagtcgcttc cgtcagggag gcggagacac aaaccatcgt cagccaaatc acgcaaaacc
     3481 tgatggaagg aatgttgatg aatccgacca ttgattcgga cagcaacaag aaaaactata
     3541 atctttacat gggaaacaat acactatcag ctgtggatgg tgagtttgcg attgatgcca
     3601 taaaaactaa gacacagttg gcagaggcac aattgaagag atttagttat gagctgaaaa
     3661 atgccttgcc ggatgcggca gccatccatt acgccgtctg caaggattcg tcgggtaacg
     3721 cgccgacatt ctccggcaat gctttttctt caaattgcga caataaggca aacggggata
     3781 ctttaattaa agtattgtgg gtaaatgatt cggcagggga ttcggatatt tcccgtacga
     3841 atcttgaggt gagcggcgac aatatcgtat atacctatca ggcaagggtc ggaggtcggg
     3901 aatgagacgt aaaatgctaa acgtaccaaa aggcagttat gatggtatga aaggttttac
     3961 cattattgaa tttttggttg cgggcatgct cagtatgatt gtcctgatgg cggtcggatc
     4021 gagttacttc acatcccgga aattaaatga tgcggcaaac gagcgtcttg ctattcaaca
     4081 ggatttgcgg aatgcggcaa cattaattgt ccgcgatgca agaatggcgg ggagcttcgg
     4141 ttgtttcaat atgtctgagc atatcgaaca ggatgttgtt tccgatgtga cgcaaaaaga
     4201 ctctcttttt tccttaaaaa ggaacagtac aaggaacagt acaaataaac ttatccccat
     4261 agcggaatct tcaaatatcg gatatcaggg ttttatccag cgccttaacg cattgatttt
     4321 ccaatacgga atcgatgatg ttaatgcaag cgccgatact accgtcgtca gcagctgtgc
     4381 cgcaatatcg aaaccgggta agcaaatcct taatttagaa gatgtaaaaa aagaattgaa
     4441 gattgtgagt caggataagg agcgaaatgg caatatagcg cgtcaaaggc atgtggtcaa
     4501 tgcctatgcg gtcggcagga ttgccggtga ggaaggtttg ttccgcttcc aattgaatga
     4561 aaagggcgag tggggtaatc ctcagttgtt ggttaaaaag attaataaaa tggatatacg
     4621 gtatatttat gtttccggct gtcctgaaga tgacgatgcc ggcaaagagg aaacattcag
     4681 atatacggat aaattcaaca gcgcccaaga tgctgttacg cctgccgggg tggaggtttt
     4741 attgagtagc ggtactgata ccaagattgc cgcttcttca gacaatcata tttatgctta
     4801 ccgtatcgat gcgacaatac gcgggggaaa tgtatgcgca aacagaacac tttgacggga
     4861 atcccgactt ctgacggaca gagggggttt gcactgttta tcgtgctgat ggtgatgatc
     4921 gtcgtggctt ttttggttgt aactgccgcg cagtcttaca ataccgagca gcggatcagt
     4981 gccaacgaat cagacaggaa attggctttg tctttggccg aggcggcttt gcgggaaggc
     5041 gaacttcagg ttttggattt ggaatatgat acggacagta aggttacatt tagcgaaaac
     5101 tgtggaaaag gtctgtgtac cgcagtgaat gtgcggacaa ataatgataa tgaagaggct
     5161 tttgacaata tcgtggtgca aggcaagccc accgttgagg cggtgaagcg ttcttgccct
     5221 gcaaattcta ccaacctgtg cattgacaat aaagggacga aatataagaa aggcacgcaa
     5281 agcgtcagca aaatgccacg ttatattatc gaatatttgg gcgtgaagaa cggagaaaat
     5341 gtttatcggg ttactgccaa ggcttggggt aagaatgcca ataccgtggt cgtccttcaa
     5401 tcttatgtaa gcaataatga tgagtaataa aatggaacaa aaagggttta cattgattga
     5461 gatgatgata gtcgtcgcga tactcggcat tatcagcgtc attgccatac cttcttatca
     5521 aagttatatt gaaaaaggct atcagtccca gctttatacg gagatggtcg gtatcaacaa
     5581 tatttccaaa cagtttattt tgaaaaatcc cctggacgat aatcagacca tcaagagcaa
     5641 actggaaata tttgtctcag gctataagat gaatccgaaa attgccgaaa aatataatgt
     5701 ttcggtgcat tttgtcaata aggaaaaacc aagggcatac agcttggtcg gcgttccaaa
     5761 gacggggacg ggttatactt tgtcggtatg gatgaacagc gtgggcgacg gatacaaatg
     5821 ccgtgatgcc gcttctgccc aagcccattt ggagaccttg tcctcagatg ccggctgtga
     5881 agccttctct aatcgtaaaa aataaggttg ttttgccaat accgtctgaa aatcaatgtt
     5941 cagacggtat ttttatgggt atagtggatt aacaaaaatc gggacaaggc gacgaagccg
     6001 cagacagtac aaatagtacg gaaccgattc acttggtgct tcagcacctt agagaatcgt
     6061 tctctttgag ctaaggcgag gcaacgctgt actggttttt gttaatccac tatacatccc
     6121 gtcattccca cgaaagtgga atctagaaat ttaatgttgc ggcactagcc aaaaaaaccg
     6181 aaaccgaacg gactagattc ccgcctgagc gggaatgacg gattttaggt tggggtcatt
     6241 tattggaaaa agcagaaacc gctccgccgt cattcccacg aaagtgggaa tccaggatgc
     6301 agggttgggg aaaccgtgtt atccgataag tttccgcacc gacaggtcta gattcccgcc
     6361 tgcgcgggaa tgacgcatcc atccgtacgg aaacctgcac cacgtcattc ccacgaacct
     6421 gcatcccgtc attcccacga aagtgggaat ctagtttttt gagtttcagt cattcccgat
     6481 aaattgcctt agcattgaat gtctagattc ccgcctgtgc gggaatgacg aatccatccg
     6541 tacggaaacc tgcaccacgt cattcccacg aacctgcatc ccgtcattcc cacgaaagtg
     6601 ggaatccagt tttttgagtt tcagtcattc ccgataaagt gccttagcat tgaatgtcta
     6661 gattcccgcc tgcgcgggaa tgacggattt tagtttgggg ggcatttatt ggaaaaagca
     6721 gaaaccgctc cgccgtcatt cccacgaaag tgggaatcca ggatgcaggg ttggggaaac
     6781 cgtgttatcc gataagtttc cgcaccgaca ggtctagatt cccgcctgcg cgggaatgac
     6841 gaacctatcc gtacggaaac ctgcatcccg tcattcccac gaacctacat tccgtcattc
     6901 ccacgaaagt gggaatccag ttttttgagt ttcagtcatt ttcaataaat tgccttagca
     6961 ttgaatgtct agattcccgc ctgcgcggga atgacgaacc tatccgtacg gaaacctgca
     7021 ccgcgtcatt cccacgaacc tgcatcccgt cattcccacg aaagtgggaa tccagttttt
     7081 tgagtttcag tcattcccga taaattgcct tagcattgaa tgtctagatt cccgcctgcg
     7141 cggga
//
LOCUS       DAXISH010000085         6545 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.085, whole genome shotgun sequence.
ACCESSION   DAXISH010000085 DAXISH010000000
VERSION     DAXISH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6545
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.085"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            221..1249
                     /locus_tag="ACFOV4_001929"
     CDS             221..1249
                     /locus_tag="ACFOV4_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slam-dependent surface lipoprotein"
                     /protein_id="HFC7619877.1"
                     /translation="MKYKALSLLPLVAALAACAGGGVAEPHVPVSIPTATPLPKGEVT
                     LSSDNGKIENINTTSTGSTSVISIQERAVTKNYFGVESQEKSFIFKTPGGAQYTLSSY
                     ADPIVPSYSSPDFKIPDRHAGQRLADGSRIFICCSDSGATREAEITKQDYMKFGAWIG
                     PNGEIDLFAGGFPVGKTPTSSSYYGSSTPETQGKGKITYQVWGIRVKDGQFVTSSYTP
                     PKGSSFTGYTNTPVLSFITANFNSNKLAGEIRGNSDYGPSVKIENATISGPSFSGNAT
                     SGGKTGNLEGKFFGKFNGSYGNTETSIGGKITFKDDRSLDTVFGGVSYVKKLDETANR
                     DTEHLTKQ"
     gene            1277..3703
                     /gene="hupB"
                     /locus_tag="ACFOV4_001930"
     CDS             1277..3703
                     /gene="hupB"
                     /locus_tag="ACFOV4_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemoglobin-haptoglobin-utilization protein HupB"
                     /protein_id="HFC7619878.1"
                     /translation="MSIPFKPVLAAAAIAQAFPAFAADPAPQSAQTLNEITVTGTHKT
                     QKLGEEKIRRKTLDKLLVNDEHDLVRYDPGISVVEGGRAGSNGFTIRGVDKDRVAINV
                     DGLAQAESRSSEAFQELFGAYGNFNANRNTSEPENFSEVTITKGADSLKSGSGALGGA
                     VNYQTKSASDYVSEDKPYHLGIKGGSVGKNSQKFSSITAAGRLFGLDALLVYTRRFGK
                     ETKNRSTEGDVKIENKGYVFSPTQSFSKYQTYVATGVARSQPDPQEWVNKSTLFKLGY
                     NFNDRNRIGWIFEDSRTDRFTNELSNLWTGTIYSPATGDYRHCQDVSYRRRSGVEYKN
                     ELEHGPWDSLKLRYDKQRIDMNTWTWDIPKNYDLRGINSEVYHSFRHIRQNTAQWTAD
                     FEKQLDFSKAVWAAQYGLGGGRGDNANSDYSYFVKLYDPKIFTSNQAKITMLIESRSK
                     YKFAYWNNAFHLGGNDRFRLNAGIRYDKNSSSAKDDPKYTTAIRGQIPHLGSERAHAG
                     FSYGTGFDWRFTKHLHLLAKYSTGFRAPTSDETWLLFPHPDFYLKANPNLKAETAKNF
                     ELGLAGSGKAGNFKFSGFQTRYRNFIELTYMGVSSDKPNSPNYAPISDGTALVSSPVW
                     QNQNRSSAWVKGLEFNGTWNLDSIGLPQGTHAGVNVSYIKGKAKQTNGQETPINALSP
                     WSAVYNLGYDAPSKRWGINAYATRTAAKKPSDTVHSNDDLNNPWPYAKHSKAYTLFDL
                     SAYLNIGKQVTLRAAAYNITNKQYYTWESLRSIREFGTVNRVDNKTHAGIQRFTSPGR
                     SYNFTIEAKF"
     gene            complement(4330..5964)
                     /gene="groL"
                     /locus_tag="ACFOV4_001931"
     CDS             complement(4330..5964)
                     /gene="groL"
                     /locus_tag="ACFOV4_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271863.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFC7619879.1"
                     /translation="MAAKDVQFGNEVRQKMVNGVNILANAVRVTLGPKGRNVVVDRAF
                     GGPHITKDGVTVAKEIELKDKFENMGAQMVKEVASKTNDVAGDGTTTATVLAQSIVAE
                     GMKYVTAGMNPTDLKRGIDKAVAALVEELKNIAKPCDTSKEIAQVGSISANSDEQVGA
                     IIAEAMEKVGKEGVITVEDGKSLENELDVVEGMQFDRGYLSPYFINDAEKQIAGLDNP
                     FVLLFDKKISNIRDLLPVLEQVAKASRPLLIIAEDVEGEALATLVVNNIRGILKTVAV
                     KAPGFGDRRKAMLQDIAILTGGTVISEEVGLSLEKATLDDLGQAKRIEIGKENTTIID
                     GFGDAAQIEARVAEIRQQIETATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KDRVEDALHATRAAVEEGVVAGGGVALLRARAALENLHTGNADQDAGVQIVLRAIESP
                     LRQIVANAGGEPSVVVNKVLEGKGNYGYNAGSGEYGDMIEMGVLDPAKVTRSALQHAA
                     SIAGLMLTTDCMIAEIPEEKPAMPDMGGMGGMGGMM"
     gene            complement(6058..6345)
                     /locus_tag="ACFOV4_001932"
     CDS             complement(6058..6345)
                     /locus_tag="ACFOV4_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFC7619880.1"
                     /translation="MTIRPLHDRVVVKRLEAEEKTASGIVLPGAAAEKPDMGEVIAVG
                     AGKIGKDGARRPLDVKVGDKIIFGKYSGQTVKADGEELLVMREEDIFGIVE"
BASE COUNT         1607 a         1909 c         1565 g         1464 t
ORIGIN      
        1 cggagccgca gacagtacaa atagtacgga accgattcac ttggtgcttg agcaccttag
       61 agaatcgttc tctttgagct aaggcgaggc aacgccgtac tggtttttgt taatccacta
      121 taccgatttt tgcaccgacc cacaaaacca gttgacatca tataacattt aaactgataa
      181 tcaaaactat tattaacaca tcatcaagat tgagtatgcg atgaaataca aagccctgtc
      241 cttactgccg cttgtcgctg cccttgccgc ctgtgccggg gggggggtag ccgaaccgca
      301 cgtccccgtg tccatcccca ccgccacgcc gctgcccaaa ggcgaggtaa cgttatcaag
      361 cgataacggc aaaatcgaaa acatcaacac caccagcacc ggaagcacat ccgtcatttc
      421 cattcaagag cgggcggtta caaaaaacta tttcggtgtt gaatcacaag aaaaatcatt
      481 catcttcaaa acacccggcg gcgcgcaata caccctttca tcctacgccg accccatcgt
      541 ccccagctac tcctcccccg atttcaaaat tcccgaccgc cacgcagggc agcggcttgc
      601 agacggcagc cgcatcttta tctgctgcag cgactccggg gcaaccagag aagcggaaat
      661 taccaaacaa gattatatga aattcggggc atggataggt cccaacggcg aaatcgacct
      721 cttcgccggc ggcttccccg tcggcaaaac accgacatca agcagttatt acggcagcag
      781 cacgcccgaa acccaaggca aaggcaaaat cacttatcag gtttggggca tccgcgtcaa
      841 agacgggcaa tttgttacct cctcttatac gccgcccaaa ggcagctctt ttaccggcta
      901 caccaacacc cccgtccttt cctttatcac cgccaatttc aacagcaaca aactggcagg
      961 cgaaatccgc ggcaacagcg attacggacc gagtgtgaaa attgaaaacg caacgatcag
     1021 cggtccgagc ttttccggca atgccacctc cggcggcaaa accggcaact tggaaggcaa
     1081 gttttttgga aaattcaacg gcagctacgg caacactgaa accagcatag gcggcaaaat
     1141 cacttttaaa gacgaccgct ccctcgatac cgtattcggc ggtgtgagtt atgtaaaaaa
     1201 acttgatgaa accgccaatc gagataccga acaccttact aaacaataaa ccatctcatc
     1261 cctacaaagg tttcttatgt ccatcccctt caaacccgta ttggctgccg ccgccatcgc
     1321 ccaagcgttt cccgcctttg cggcagaccc cgcgccgcag tccgcccaaa cgctgaacga
     1381 aatcaccgtt accggcacgc acaaaaccca aaaactcggc gaagaaaaaa tccgccgcaa
     1441 aaccttagac aagctcttgg tcaacgacga acacgacctg gtgcgctacg accccggcat
     1501 ttccgtcgtc gaaggcggca gggcgggttc taacggcttt accatacgcg gcgtggacaa
     1561 agaccgcgtc gccatcaacg ttgacgggct ggcgcaggcg gaaagccgct cttccgaagc
     1621 cttccaagaa ttgttcggcg cgtacggcaa cttcaacgcc aaccgcaaca cttccgagcc
     1681 ggaaaacttt tccgaagtaa ccatcaccaa aggcgcggac tcgctcaaat ccggcagcgg
     1741 cgcattgggc ggcgcagtca attaccaaac caaatccgca agcgattatg tttccgaaga
     1801 caagccctac catttgggga taaagggcgg cagcgtcggc aaaaacagcc aaaagttcag
     1861 cagcatcacc gccgccggca ggctctttgg tttggatgcc ttattggttt atacccgccg
     1921 cttcggcaaa gaaaccaaaa accgctcgac cgagggcgat gtcaaaattg aaaacaaggg
     1981 atatgttttc agcccaaccc aatcattcag caagtaccag acctacgtag ccacaggggt
     2041 tgcgcgctcc caacccgacc cgcaagaatg ggtaaacaaa agcaccttgt tcaagctggg
     2101 ctacaatttc aacgaccgca accgcatcgg ctggattttt gaagactccc gcaccgaccg
     2161 ttttaccaac gagctgtcta atttgtggac gggtacaatt tactctcccg caacgggcga
     2221 ctaccgccac tgccaagacg tgagctaccg ccgccgctcc ggcgtcgaat acaaaaacga
     2281 attggaacac ggcccgtggg acagcctcaa gctgcgctac gacaagcagc gcatcgatat
     2341 gaacacttgg acttgggaca tcccgaaaaa ttacgatttg cgcggcatca acagtgaagt
     2401 ttaccattcg ttccggcata tccgccaaaa caccgcgcaa tggactgccg attttgaaaa
     2461 acaactcgac ttttccaaag ccgtttgggc ggcgcaatac ggcttgggcg gcggcagagg
     2521 ggacaatgcc aactcggatt acagctattt cgtaaaactg tacgacccca aaatcttcac
     2581 ttccaaccaa gccaaaatca cgatgctgat cgaaagccgg tcgaaatata aatttgccta
     2641 ttggaacaat gcgtttcact tgggcggcaa cgaccgcttc cgcctgaatg cgggcatacg
     2701 ctacgacaaa aacagcagca gcgcgaaaga cgatccgaaa tacaccaccg ccatccgggg
     2761 gcagattccc catttgggtt cggaacgcgc gcacgcgggc ttcagctacg gcacggggtt
     2821 cgactggcgg tttaccaagc atctgcactt gttggcaaaa tacagcaccg gcttccgcgc
     2881 accgacttcg gacgaaacct ggctattgtt cccgcatcct gacttttacc ttaaagcaaa
     2941 ccccaacctg aaggcagaaa ccgccaaaaa cttcgagctg ggacttgccg gcagcggcaa
     3001 agcaggaaac tttaaattct ccggtttcca aacccgctac cgtaatttta tcgaactgac
     3061 ctacatgggc gtatcctcag acaagcctaa cagccctaat tatgcgccga tttccgacgg
     3121 tactgcattg gtcagctcgc ccgtttggca aaaccaaaac cgctcctcgg catgggtgaa
     3181 aggtttggaa tttaacggca catggaacct cgacagcatc ggtttgccgc aaggcacgca
     3241 cgcaggtgtc aatgtcagct acatcaaagg caaggccaaa caaaccaacg gacaggaaac
     3301 ccctattaac gccctttcgc catggagtgc ggtttacaat ctgggctacg acgctccttc
     3361 caaacgttgg ggcatcaacg cctacgccac gcgcaccgcc gccaaaaagc cgtccgacac
     3421 cgtccacagc aacgacgact tgaacaaccc gtggccttat gccaaacaca gcaaggccta
     3481 tacgctgttc gacctttccg cctacctcaa catcggcaaa caggttacgc tccgcgccgc
     3541 cgcgtacaac attaccaaca agcagtacta cacttgggaa tctttacgca gcatccgcga
     3601 gttcggcacg gtcaaccgcg ttgacaacaa aacccacgcc ggcatccaac gctttacctc
     3661 gccgggcagg agctacaatt tcaccatcga agcgaagttc taagctcctg atgtgccaat
     3721 gccgtctgaa acccgatgat ttgggtttca gacggcattt tttacggtcg caccgccgcc
     3781 ccctttcagg cttgtaccaa gcccaatccc gcaactctcc gtcattcccg caactctccg
     3841 tcattcccgc aactctccgt cattcccgcg actctccgtc attcccacgg aagtgggaat
     3901 ctagaaacgc aaagctgcaa gaatttatcg gaaatgactg aaactcaacg aacctggatt
     3961 cccgcctgcg cgggaatgac gaagctatcc gcacagaaac ctgcaccacg tcattcccac
     4021 gaaagtggga atccagaacg taaaatctga agaaaccgtt ttatccgata cgtttccgca
     4081 ccgacagacc tagattcccg ctttcgcggg aatgacggcg gaaaggttgc tgtttttccg
     4141 ataaattcct gccgctcttc gtttttggga tggcgggaaa taaaacaaaa gcgcgcgtat
     4201 caaaaaacaa aaatgcaaag aacggcgttg gcaattttaa ggtttgcgcc ttagccgcac
     4261 ttattcgcaa aaaaaaccgc acggcgttga ccgtgcggct tgttgtctga aagcttcaga
     4321 cggcatttct tacatcatgc cgcccatacc gcccatgccg cccatgtcag gcatagcagg
     4381 tttttcttca gggatttcag cgatcatgca gtctgtggtc agcatcagac cggcgataga
     4441 tgcggcgtgt tgcagcgcgg aacgggttac tttggcagga tcgagtacgc ccatttcaat
     4501 catatcgccg tattcgccgc tgccagcgtt gtaaccgtag ttgcctttgc cttccaacac
     4561 tttgttcacg actacgctgg gttcgccgcc tgcgttggca acgatttggc gcagcggaga
     4621 ctcaatggcg cgcaagacga tttgtacgcc tgcgtcttga tcggcattgc cggtgtgcag
     4681 gttttccaga gcggcacggg cgcgcaacag ggctacgccg ccgcctgcaa ccacgccttc
     4741 ttcaacggct gcgcgggtag catgcagcgc gtcttctacg cggtcttttt tctctttcat
     4801 ttcgacttcg gtagcggcac cgactttgat tactgccacg ccgcctgcca gtttggccac
     4861 gcgctcttgc agtttttctt tgtcgtaatc gctggttgcg gtttcgattt gttggcggat
     4921 ttcggcaaca cgcgcttcga tttgggctgc gtcgccgaag ccgtcgatga tggtggtgtt
     4981 ttctttaccg atttcgatgc gtttggcttg acccaagtcg tccaaagtcg ctttttccag
     5041 agacaggccg acttcttcgg aaatcaccgt gccgccggtc aggatggcga tgtcttgcag
     5101 catcgctttg cggcggtcgc caaagcccgg agctttaacg gcaacggttt tcaggatgcc
     5161 gcgaatgttg tttaccacca aagtcgccaa ggcttcgcct tctacgtctt cagcgataat
     5221 caagagcgga cggctggctt ttgccacttg ttccaaaaca ggcaacaagt cgcggatgtt
     5281 gctgattttt ttgtcgaaca gcaatacaaa cggattgtcc aagccggcga tttgtttttc
     5341 cgcatcgttg atgaagtaag gagacaggta gccgcggtcg aattgcatac cttcaaccac
     5401 gtccagctcg ttttccaaag atttgccgtc ttcaacggta atcacgcctt ctttgccgac
     5461 tttttccatc gcttcggcaa taatcgcgcc gacttgttcg tcggagttgg cggaaatcga
     5521 gccgacttgg gcgatttctt tagaagtgtc gcaaggtttg gcgatgtttt tcagctcttc
     5581 aaccaaagcg gcgacggctt tgtcgatacc gcgtttcagg tcggtcgggt tcataccggc
     5641 ggtaacgtat ttcatacctt cggcaacgat ggattgcgcc agtacggtgg cggtagtcgt
     5701 accgtcgccc gccacgtcgt tggttttgga cgcgacttct tttaccattt gcgcgcccat
     5761 attttcaaac ttgtctttca gttcgatttc tttagcgacg gttacgccgt ctttggtaat
     5821 gtgcgggccg ccgaaagcgc ggtcaaccac cacgttgcgg cctttgggac ccagggttac
     5881 gcgcacggcg tttgccagaa tgttcacgcc gtttaccatt ttttgacgga cttcattgcc
     5941 gaattgtacg tcttttgctg ccatttcaat tctccaaaaa tcattaaaac tgtctgataa
     6001 aaccgtttat gccgtctgaa ggcggtttgc cgtttcagac ggcatcatca ttcgcactta
     6061 ttcaacgatg ccgaaaatat cttcttcgcg cattaccaac agctcttcgc cgtcggcttt
     6121 tacggtttgg ccgctgtatt tgccgaaaat gattttgtcg ccgactttga catccagcgg
     6181 acggcgcgcg ccgtctttac cgattttgcc cgcgcccacg gcgatgactt cgcccatatc
     6241 gggtttttcg gcggccgcac ccggcaaaac gatacccgat gcggtttttt cttcagcttc
     6301 caagcgtttg acgacgacgc ggtcgtgtaa aggacggatg gtcatattta tgctccgata
     6361 aaatggtttg aaaacaatca tctgcccgaa cggttcggac agattgaagt ggaaaccggg
     6421 ctgccgcctg ccggccgccc gtatgaatcg gcaaaattag ggtgtgtgcg ggcaaattca
     6481 agtgaggcgg aaaaaattta tttccgccgt tttttatagt ggactaaatt taaggggctg
     6541 tacta
//
LOCUS       DAXISH010000086         6386 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.086, whole genome shotgun sequence.
ACCESSION   DAXISH010000086 DAXISH010000000
VERSION     DAXISH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6386
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.086"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(1183..4017)
                     /gene="lbpA"
                     /locus_tag="ACFOV4_001933"
                     /gene_synonym="tbpA"
     CDS             complement(1183..4017)
                     /gene="lbpA"
                     /locus_tag="ACFOV4_001933"
                     /gene_synonym="tbpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoferrin/transferrin-binding protein LbpA"
                     /protein_id="HFC7619881.1"
                     /translation="MNKKHGFQLTLTALAIATAFPAYAAQAGGATPDAAQTQSLKEVT
                     VRAAKVGRRSKEATGLGKIVKTSETLNKEQVLGIRDLTRYDPGVAVVEQGNGASGGYS
                     IRGVDKNRVAVSVDGVAQIQAFTVQGSLSGYGGRGGSGAINEIEYENISTVEIDKGAG
                     SSDHGSGALGGAVAFRTKEAADLISDGKSWGIQAKTAYGSKNRQFMKSLGAGFSKDGW
                     EGLLIRTERQGRETRPHGDIADGVAYGINRLDAFRQTHDIQSNKTGQFFLVEGENTLK
                     PVAKLAGYGIYLNRQLNRWVKERIEQNKPLSAEEEAMVREAQARHENLSAQAYTGGGR
                     ILPDPMDYRSGSWLAKLGYRFGGRHYVGGVFEDTKQRYDIRDMTEKQYYGTDEAEKFR
                     DKSGVYDGDDFRDGLYFVPNIEEWKGDKKLVRGIGLKYSRTKFIDEHHRRRRMGLLYR
                     YENEAYSDNWADKAVLSFDKQGVATDNNTLKLNCAVYPSVDKSCRASADKPYSYDSSD
                     RFHYREQHNVLNASFEKSLKNKWTKHHLTLGFGYDASNAISRPEQLSHNAARISEHTG
                     EYTADDKDKYRLGKPEVVEGSVCGYIETLRSRKCVPRKINGSNIHISLNDRFSIGKYF
                     DFSLGGRYDRKNFTTSEELVRSGRYVDRSWNSGIVFKPNRHFSLSYRASSGFRTPSFQ
                     ELFGIDIYHDYPKGWQRPALKSEKAANREIGLQWKGDFGFLEISSFRNRYTDMIAVAD
                     HKTKLPNQAGQLTEIDIRDYYNAQNMSLQGVNILGKIDWNGVYGKLPEGLYTTLAYNR
                     IKPKSVSNRPGLSLRSYALDAVQPSRYVLGFGYDQPEGKWGANIMLTYSKGKNPDELA
                     YLAGDQKRYSTKRASSSWSTADVSAYLNLKKRLTLRAAIYNIGNYRYVTWESLRQTAE
                     STANRHGGDSNYGRYAAPGRNFSLALEMKF"
     gene            complement(4014..6218)
                     /locus_tag="ACFOV4_001934"
     CDS             complement(4014..6218)
                     /locus_tag="ACFOV4_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="HFC7619882.1"
                     /translation="MCKPNYGGIVLLPLLLASCIGGNFGVQPVVESTPTAYPVTFKSK
                     DVPTSPPAGPSVETTPVNRPAVGAAMRLPRRNTAFHREDGTVIPDSKQAEEQLSFKEE
                     DILFLYGSKEDQRQQLKDKIRQPNSTASIITSEKKNARYSYKFVDAGYVYVRGEDEIK
                     WTSDHKQFSNRLGYDGFVYYSGEHPSQSLPSAGKVKYFGNWQYMTDAKRHRAGKAVGI
                     DNLGYITFYGNDVGATSYAAKDVDEREEHPAEYTVDFDKKILKGELIKNQYVQKKNDP
                     TEPKKPLTIYNITADLNGNRFTGSAKVNTELKTRHADKEYLFFHTDADRRLEGGFFGD
                     KGEELAGRFISNDNSVFGVFAGKQKTDASGTNPAMPSEKHTKILDSLKISVDEASDKN
                     PREFAISTMPDFGHPDKLLVEGREIPLVNKEQTIKLADGRKMTVSACCDFLTYVKLGR
                     IKTERPAAKPKAQDEEDSDIDNGEESEDEIGDEEEGTEDAAAGDEGSEEDEATENEDG
                     EEDEAEEPEEESSAEGNGSSNAILPVPEASKGRDIDLFLKGIRTAETNIPQTGEARYT
                     GTWEARIGKPIQWDNHADKEAAKAVFTVDFGKKSISGTLTEKNGVEPAFRIENGVIEG
                     NGFHATARTRDDGIDLSGQGSTKPQIFKANDLRVEGGFYGPKAEELGGIIFNNDGKSL
                     GITEGTENKVEADVDVDVDVDADADVEQLKPEVKPQFGVVFGAKKDNKEVEK"
BASE COUNT         1416 a         1687 c         1475 g         1808 t
ORIGIN      
        1 taaataccca caagctaaaa tcctgttatt ttcacaaaaa cagaaaacca aaaacagcaa
       61 cctgaaattc gtcattcccg cgcaggcggg aatctggttc gttcggtttc gcttgtttta
      121 agtttcgggt aacttccact tcgtcattcc cgcgcaggcg ggaatccagt gcgttgagct
      181 tcagctattt agaataaatt ttgaaactct aatcgcgtca ttcccacgaa agtgggaatc
      241 cagtttcttg agtttcagtc attcccgata aattgcctta gcattgaatg tctagattcc
      301 cgcctgcgcg ggaatgacga atccatccat acggaaacct gcatcccgtc attcccacga
      361 acctgtatcc cgtcattccc acgaaagtgg gaatccagct ttttgagttt cagtcatttc
      421 cgataaattg ccttaacatt gaatgtctag attcccgcct gcgcgggaat gacgggattt
      481 gaaattgcgg catttatcgg gagcaacaga agccgctctg ccgtcattcc cacgaaagtg
      541 ggaatccagc tttttgagtt tcagtcattt ccgataaatt gccttagcat tgaatgtcta
      601 gattcccgcc tgcgcgggaa tgacgggatt tgagattgcg gcatttatca ggagcaacag
      661 aagccgctct gccgtcattc ccacgaaagt gggaatccag ttttttgagt ttcagtcatt
      721 cccgataaat tgccttagca ttgaatgtct agattcccgc ctgcgcggga atgacggatt
      781 ttaggttggg gtcatttatt ggaaaaagca gaaaccgctc tgccgtcatt cccacgaaag
      841 tgggaatcca gctttttgag tttcagtcat tcccgataaa ttgccttagc attgaatgtc
      901 tagattcccg cctgcgcggg aatgacggga tttgagattg cggcatttat caggagcaac
      961 agaagccgct ctgccgtcat tcccacgaaa gtgggaatcc agctttttga gtttcagtca
     1021 tttccgataa attgccttag cattgaatgt ctagattccc gcctgcgcgg gaatgacggc
     1081 ggaaatcttg tttatatcga atcaaaaaaa cctgcacctt aatcagttgg cggtttagtc
     1141 cgacttttgg ggtgcagatc aagctttcag acggtatttc ctttaaaact tcatttcgag
     1201 cgcgaggctg aagttcctgc ccggtgcggc ataccttcca tagttgctgt cgccgccgtg
     1261 ccggtttgcc gtgctttccg cggtctggcg caaggattcc caagtaacgt agcggtagtt
     1321 gccgatattg tagatagccg ccctcaaggt cagccgtttt ttcagattca gataggcgga
     1381 aacgtctgcc gtcgaccaag aagacgacgc tctttttgtc gaatatcgtt tttgatcgcc
     1441 tgccagataa gcaagctcgt cagggttttt ccctttggaa taggtcagca taatgtttgc
     1501 gccccatttc ccctctggct ggtcgtatcc gaaccccaaa acataacgcg acggctgtac
     1561 cgcatccaaa gcatagctgc ggagggacag tcccggccgg ttggataccg atttcggttt
     1621 gatgcggttg tacgccaaag tcgtgtacaa accttcgggc agtttgccat acacgccgtt
     1681 ccagtcgatt tttcccaata tattaacgcc ttgaagcgac atattttggg cattgtaata
     1741 atcgcgtata tcaatctctg tcaattgtcc tgcctgattc ggcaatttgg ttttgtgatc
     1801 ggcaacggca atcatatcgg tataacggtt gcggaagctg ctgatttcca aaaagccgaa
     1861 atcgcccttc cactgcaaac cgatttcgcg gttggctgcc ttttccgatt tcagggcggg
     1921 acgctgccag cctttcggat aatcgtgata aatgtctatc ccgaaaagtt cttggaatga
     1981 gggcgttctg aagccgctgg aggcgcggta agacaaagaa aaatgccggt tcggtttgaa
     2041 cacgatgccg ctgttccacg aacggtcaac ataccgcccg ctgcggacga gttcttccga
     2101 cgtggtgaag tttttccggt catacctgcc acccaagctg aaatcaaaat atttgccgat
     2161 tgaaaaacgg tcgttcaaag aaatatggat attgctgccg ttgatttttc ttggcacgca
     2221 tttgcgggaa cgcagggttt cgatgtagcc gcagaccgac ccttcgacga cttcgggctt
     2281 acccaaacgg tacttgtctt tgtcgtcggc ggtgtactcc cccgtgtgtt ccgaaatcct
     2341 tgccgcattg tgggaaagct gttcagggcg ggaaatcgcg ttggaagcat cgtaaccgaa
     2401 gcccaaagtc agatggtgtt tcgtccattt gtttttcagc gatttctcaa acgaggcatt
     2461 caaaacattg tgctgttcgc ggtagtggaa acggtcgctg ctgtcgtagg aatacggttt
     2521 gtccgccgac gcgcggcagg atttgtccac ggaaggatac acggcgcaat tcagcttcag
     2581 cgtgttgttg tcggttgcca cgccctgttt gtcaaacgac aacaccgcct tatccgccca
     2641 gttgtcagaa tacgcttcgt tttcataacg gtacagcaaa cccatacggc ggcggcggtg
     2701 atgttcatca ataaatttgg tgcgggaata tttcaaacct atgcccctga ccaacttttt
     2761 atcgcccttc cactcttcta tattcggcac aaaatacaag ccgtcgcgga aatcgtcgcc
     2821 gtcgtacacc ccactcttgt ctctaaactt ttccgcctcg tccgtaccgt aatactgttt
     2881 ttccgtcata tcgcggatgt cgtaacgctg tttggtatcc tcaaacacgc cgccgacata
     2941 atgcctgccg ccgaagcggt agcccagctt ggcaagccaa gagccgctgc ggtaatccat
     3001 cggatcgggc aatatcctgc cgccgcccgt gtaagcttgg gcggacaggt tttcgtggcg
     3061 cgcctgcgcc tcccgcacca tcgcttcttc ttcagcactt aaaggcttat tttgttcaat
     3121 acgttctttt acccagcggt taagctggcg gttcaaatat atcccgtagc ccgccaattt
     3181 tgccacgggc ttgagtgtat tctcgccctc tactaagaaa aattgccctg ttttattgct
     3241 ttgaatatcg tgtgtctggc ggaacgcgtc caaacggttt atgccgtatg ccaccccgtc
     3301 tgcaatatcg ccgtgcgggc gcgtttcccg cccttgacgt tcggttcgga ttagcagccc
     3361 ttcccaaccg tctttactga accccgcgcc gagcgacttc ataaattggc ggtttttact
     3421 gccgtaggcg gtttttgcct gtattcccca actcttgccg tctgaaatca ggtctgccgc
     3481 ttctttggtg cggaaggcga ccgcgccgcc gagtgcgccg ctgccgtgat cggacgaacc
     3541 ggcacctttg tcgatttcca ccgtgctgat gttttcatat tcgatttcgt tgattgcacc
     3601 gctgccgccg cgtccgccgt atccgctcaa cgatccctgc acggtaaacg cctgtatttg
     3661 ggcaacgccg tcaaccgaaa ccgccacacg gtttttatcc acgccgcgta tcgagtagcc
     3721 gccgctcgcg ccgttgccct gttcgacaac cgccacgccc ggatcgtagc gcgtcaggtc
     3781 gcggataccg agtacctgtt ctttgttcaa cgtttccgac gttttgacga ttttgcccaa
     3841 accggtcgcc tctttcgatc gccgtcccac tttggcggca cggacggtaa cctctttcag
     3901 ggattgggtc tgcgccgcat caggtgtcgc cccccccgct tgggcagcat aagccggaaa
     3961 agcggttgca atggccaagg cggtcagggt aagctgaaaa ccgtgtttct tattcatttt
     4021 tccacctctt tattatcttt cttcgcaccg aataccacgc cgaattgggg tttaacttca
     4081 ggttttaact gttcaacatc agcatcagca tcaacatcaa catcaacatc aacatcagct
     4141 tcaactttat tttcagtacc ttcagttata ccaagagatt tcccatcatt attgaaaata
     4201 ataccgccca attcctccgc cttcgggccg taaaatcctc cttctacacg aagatcatta
     4261 gctttgaaga tctgcggttt ggtcgaaccc tgcccggaaa ggtcgatgcc gtcatcccga
     4321 gtgcgcgctg tcgcatggaa accgttgccc tcaatcacgc cgttttcaat acggaaagca
     4381 ggttctacac cgtttttctc cgtcagcgtt ccggaaatcg atttcttgcc gaaatcaacg
     4441 gtaaatactg cttttgccgc ttctttatcc gcatgattgt cccattgaat gggtttgccg
     4501 atacgcgctt cccaagtgcc ggtatagcgt gcttctccag tttgcggaat attcgtttct
     4561 gccgtgcgga tacctttcag gaaaaggtcg atatccctgc ctttagaggc ttccgggaca
     4621 ggcaggatgg cgtttgaact gccgttgcct tctgccgacg attcttcttc aggttcttca
     4681 gcttcgtctt cttcgccgtc ttcgttttct gtggcttcgt cttcttcgct gccttcatct
     4741 cctgcggctg catcttcggt gccttcttct tcatcgccga tttcgtcttc gctttcttcg
     4801 ccattatcaa tgtccgaatc ctcttcgtcc tgcgccttcg gtttggcggc ggggcgttcg
     4861 gtttttatcc gtccgagttt cacataggtc agaaaatcgc aacaagcact gacggtcatt
     4921 ttcctgccgt cggcaagctt gatggtttgt tctttgttta ccaaaggaat ttcacgccct
     4981 tcgacaagaa gtttgtcggg atgaccaaaa tcgggcatag tggaaatggc aaactcacgg
     5041 ggatttttat cacttgcctc gtcaacggaa atttttagag aatccaagat tttggtgtgt
     5101 ttttcagacg gcatagcagg atttgtgcct gatgcgtctg ttttttgttt gcctgcgaat
     5161 acgccgaata cgctgttgtc gttactgata aaccgtccgg caagctcttc ccccttatcg
     5221 ccgaaaaaac cgccctcaag ccgccgatcg gcatcggtat ggaaaaacaa atattcttta
     5281 tcagcgtggc gcgtcttcaa ctcggtgtta actttggcac tgccggtaaa gcggttgccg
     5341 tttaaatcgg cagtaatgtt gtaaatggtc agcggttttt taggttccgt tggatcattt
     5401 ttcttttgca catactgatt tttaatcagc tcgcccttta ggattttttt gtcgaaatca
     5461 accgtatatt cggcgggatg ctcttccctt tcgtcgacat ccttagccgc ataagaagtt
     5521 gcaccaacat cgttaccata aaatgtgata taacccaaat tgtcaatgcc aaccgcctta
     5581 cctgctcgat gacgtttggc atcagtcata tattgccagt tgccgaaata ttttaccttt
     5641 cccgcgctcg gtaaagattg cgaaggatgt tctccagaat aatatacaaa accatcataa
     5701 cctaagcggt tggaaaactg cttgtgatct gaagtccact taatttcatc ttcccccctt
     5761 acatatacat aacctgcatc tacaaattta taactatatc ttgcattttt cttttccgat
     5821 gtgataatgc ttgccgtaga atttggttga cgaattttat ctttaagctg ctgacgttga
     5881 tcttctttgg aaccgtataa aaacaggata tcttcctctt taaacgacag ctgttcttct
     5941 gcttgtttgc tatcgggaat taccgtgcca tcttcacgat gaaaagcagt attccgcctt
     6001 ggcagccgca ttgccgcacc gacggcgggc cggttgaccg gcgtggtttc taccgaaggc
     6061 ccggcagggg gcgaagtggg aacgtcctta gacttgaaag tgacggggta cgcggtcggc
     6121 gttgattcga caacaggctg cacgccgaaa ttgccgccaa tacaagatgc caaaagtaag
     6181 ggcaacaaga caatgccgcc ataattcggt ttacacatcc ctacttttcc tcctatttga
     6241 ttaataataa ttatcattat attaatatgt acagataata tcaagccgtt tttatagtga
     6301 attaacaaaa atccggacaa ggcgacgagc cgcagacagt acagatacat cccgtcattc
     6361 ccacgaacct gcatcccgtc attccc
//
LOCUS       DAXISH010000087         6237 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.087, whole genome shotgun sequence.
ACCESSION   DAXISH010000087 DAXISH010000000
VERSION     DAXISH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6237
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.087"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            304..750
                     /gene="yciA"
                     /locus_tag="ACFOV4_001935"
     CDS             304..750
                     /gene="yciA"
                     /locus_tag="ACFOV4_001935"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HFC7619883.1"
                     /translation="MQHEEGNRQRPQGELLLRTVAMPRDTNPNQDIFGGWIMSQMDLG
                     GGILAAEIARGRIVTVAVQEMNFIRPVKVGNVVCCYGHCVRVGNTSLQLKVEVWVKTL
                     MNDCVTEDRHLVTEAVFTYVAIDAEGNPRPIPKEGNPKLSGLLPTP"
     gene            complement(801..1622)
                     /locus_tag="ACFOV4_001936"
     CDS             complement(801..1622)
                     /locus_tag="ACFOV4_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFC7619884.1"
                     /translation="MAVLITGASAGFGEAMCRAFVGAGYRVIGAARRADRLQVLADEL
                     GALFYPLEMDVSRRESVENALNGIPDEFSDIDCLINNAGLALGLDTADKADFEDWETM
                     IQTNVLGLTFLTRKILPQMVERGGGYVMNLGSIAGNYAYAGSNVYGATKAFVRQFSLN
                     LRAELADKNIRVTNIEPGLCGNTEFSNVRFKGDDEKAAGVYEGVEFIRPEDIAETALW
                     LYRRPAHMNVNTIEIMPVAQTFAGMKVIKKAVPEVREDFEKQSMSLFSRIRSWFK"
     gene            1741..2199
                     /locus_tag="ACFOV4_001937"
     CDS             1741..2199
                     /locus_tag="ACFOV4_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HFC7619885.1"
                     /translation="MKTQISLAAAAITLLLSACGGSGIPSQPKGEISENRTAAFKSMM
                     PDFSRMGKMVKGEEPYDVEKFKQAAAAFAESSKKPFTLFESDPQGNGRALPAVWSDGA
                     KFEAEKTKFAAAVEKLNAAAQTGKLDEIKAAYGETGASCKSCHDSFRAPE"
     gene            complement(2363..3478)
                     /gene="lst"
                     /locus_tag="ACFOV4_001938"
     CDS             complement(2363..3478)
                     /gene="lst"
                     /locus_tag="ACFOV4_001938"
                     /EC_number="2.4.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyllactosaminide
                     alpha-2,3-sialyltransferase"
                     /protein_id="HFC7619886.1"
                     /translation="MGLKKACLTVLCLIVFCFGIFYTFDRVNQGERNAVSLLKDKLFN
                     EEGEPVNLIFCYTILQMKVAERIMAQHPGERFYVVLMSENRNEKYDYYFNQIKDKAER
                     AYFFHLPYGLNKSFNFIPTMAELKVKAMLLPKVKRIYLASLEKVSIAAFLSTYPDAEI
                     KTFDDGTGNLIQSSSYLGDEFSVNGTIKRNFARMMIGDWSIAKTRNASDEHYTIFKGL
                     KNIMDDGRRKMTYLPLFDASELKAGDETGGTVRILLGSPDKEMKEISEKAAKNFNIQY
                     VAPHPRQTYGLSGVTTLNSPYVIEDYILREIKKNPHTRYEIYTFFSGAALTMKDFPNV
                     HVYALKPASLPEDYWLKPVYALFTQSGIPILTFDDKD"
     gene            3705..3845
                     /locus_tag="ACFOV4_001939"
     CDS             3705..3845
                     /locus_tag="ACFOV4_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/arginine repetitive matrix 2"
                     /protein_id="HFC7619887.1"
                     /translation="MPPHIRHSTSDTAAKSGKTISPFLSRRRVQTRQDRTKREQSRQN
                     MP"
     gene            3912..6137
                     /locus_tag="ACFOV4_001940"
     CDS             3912..6137
                     /locus_tag="ACFOV4_001940"
                     /EC_number="1.1.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HFC7619888.1"
                     /translation="MTQKSTIVYTHTDEAPALATQSLLPIVQAFARHADIDVKTADIS
                     LSGRILAAFPEYLTEAQRVPDALAELGELVKQPDANVIKLPNISASVPQLTAAIKELQ
                     SKGFAVPDYPADPQTDEEKAVRERYDRIKGSAVNPVLREGNSDRRAPKAVKNFAKKNP
                     HSMGAWTKDSKTHVATMQSGDFFHNEQSVTVPEATSVSIVFTDKQGNKKELRAPVALK
                     AGEIIDATVMSKKALLAFLAEQVKDAKAKGVLFSLHMKATMMKVSDPIIFGHAVKVFF
                     APVFEKFGGKLAAAGVNVNNGFGNLLANLDKLDADTRAAVEAEIAAVYAANPDLAMVD
                     SDKGITNLHVPSDVIVDASMPAMIRNSGRMWDKDGKAQDTKAVIPDSSYAGVYQATID
                     FCREHGAFDPTTMGTVPNVGLMAQAAEEYGSHNKTFEIEADGQVQVIDAAGKVLMQHD
                     VEAGDIWRMCQTKDAPVKDWVQLAVNRARLSNTPAVFWLDENRPHDKSLLAKVKAYLA
                     ELDTNGLDIRVLAPEEAAKFSLGRLKNGEDTISVTGNVLRDYLTDLFPILELGTSAKM
                     LSIVPLMNGGGMFETGAGGSAPKHVQQFLEENHLRWDSLGEFLALAVSFEHLAQKTGN
                     TKAQVLADTLDAATEKLLLNDKSPKRKAGELDNRGSHFYLTLYWAQELAAQDKDAELK
                     AAFTPLAAALTADEAKIVAELSAVQGKAADIGGYYAANPEKAAQVMRPSVTFNQALNA
                     L"
BASE COUNT         1669 a         1829 c         1379 g         1360 t
ORIGIN      
        1 ttcagttgcg ttccgacaac accgcaatct cgaaattcgt cattcccgcg caggcgggaa
       61 tccagacctg tccgcacaga aacttatcgg ataaaaacag ttgctcaaac ccctcgttct
      121 agattcccac ttccgtggga atgacggttc agttgctacg gccccgccct acaatacgcc
      181 ttgcgaatct gttccgcgcc cgcccttgta tgtctcaaat gggttaaact acgcacttcc
      241 cgacttcccg tttcgggcag aggtgcaggt tcgatttata tttcaataaa acaaggaaac
      301 tttatgcagc acgaagaagg caaccgccaa cgccctcaag gcgaactgct cctgcgtacc
      361 gtcgctatgc cgcgcgatac caatcccaac caagacattt tcggcggctg gattatgtcg
      421 cagatggatt tgggcggcgg catattggcg gcggaaatcg cgcggggacg catcgttacc
      481 gtcgccgttc aggaaatgaa cttcatccgc ccggtcaagg tcggcaacgt cgtctgctgc
      541 tacgggcatt gcgtccgcgt gggcaacact tccctccagc ttaaagtcga agtctgggtg
      601 aaaactttga tgaacgattg cgttaccgaa gaccgccacc tcgtaaccga agccgtgttc
      661 acttatgttg ccatcgatgc ggaaggcaat ccgcgcccga ttccgaaaga aggcaacccc
      721 aaattgtcgg gcttattgcc tactccgtaa aaatacccgt aaaaatgccg tctgaaactg
      781 tcttcagacg gcattccgca tcatttgaac caagacctga tgcgggaaaa cagcgacata
      841 ctttgttttt caaagtcttc ccgcacttcc ggcacggctt tttttatcac tttcattcct
      901 gcaaaagtct gcgccacggg cataatttca atcgtgttca cattcatatg cgccggccgg
      961 cggtacagcc acaatgcggt ttccgcaata tcttcggggc ggataaattc cacaccctca
     1021 tacacgcctg ctgccttctc gtcatcgcct ttgaagcgca cgttggaaaa ctccgtattg
     1081 ccgcacaaac ccggctcgat attggtaacg cggatatttt tatccgccaa ctccgcgcgc
     1141 aaattcaggc tgaactggcg cacaaacgcc ttggtcgccc cgtaaacgtt gctgccggca
     1201 taagcataat tacccgcaat cgaacccaaa ttcatcacat aaccgccgcc gcgttccacc
     1261 atttgcggca aaatcttgcg cgtcaggaac gtcaaaccca aaacattggt ttgaatcatt
     1321 gtttcccaat cttcaaaatc cgccttgtcc gccgtgtcca aacccaaagc cagcccggca
     1381 ttgttgatga ggcagtcgat gtcggaaaat tcatcgggga tgccgtttaa ggcattttcc
     1441 accgactcgc gtcgcgacac gtccatttcc aaagggtaaa acaaagcacc caattcatcc
     1501 gccaaaacct gaagcctgtc cgcacggcgc gccgcaccga taacgcggta tccagccccg
     1561 acaaacgcgc ggcacatcgc ttcgccgaat cctgccgaag caccggtaat taaaacagcc
     1621 attgtttttc ctttctttct cgtttcccaa acctgtttca ggtatcataa cacccttcag
     1681 acggcatcgc gccgactgaa aatgacaaca accataccac cacgacagga cacattcaat
     1741 atgaaaaccc aaatcagcct tgctgctgcc gccatcacac tgctcctttc cgcctgcgga
     1801 ggcagcggaa taccttccca acccaaaggc gaaatttccg aaaaccgcac cgccgcgttc
     1861 aaatctatga tgcccgactt ctcgcgtatg ggcaaaatgg tcaaaggcga agagccttac
     1921 gatgtcgaaa aattcaaaca ggctgccgcg gcgtttgccg aaagcagcaa gaaaccgttc
     1981 acactttttg agtccgatcc gcaaggcaac ggccgcgccc tgccagccgt ttggtcggat
     2041 ggtgcaaaat ttgaagccga aaaaacaaaa ttcgccgccg ccgtcgaaaa actcaatgcc
     2101 gcagcacaaa ccggcaaact ggatgaaatc aaagccgcct acggcgaaac cggcgcaagc
     2161 tgcaaatcct gccacgacag tttccgcgca cccgaataac atccgaaaca gaacaatgcc
     2221 gtctgaagcc ttcagacggc attttctttg ccatttcagc acacgcaaag caatcagaaa
     2281 ttatcgtcaa ttcaaaaaat acgccatatc ctgatttttg ccttacttac tccgccattt
     2341 tctattttga tttgctatgc gattaatctt tatcgtcaaa tgtcaaaatc gggatgccgg
     2401 attgggtaaa cagggcatac accggcttga gccaataatc ttccggaagg gaagccggtt
     2461 tcaatgcgta aacgtgcaca ttgggaaaat ccttcatcgt caacgccgcg ccgctgaaaa
     2521 aggtataaat ttcatacctc gtatgcgggt ttttcttaat ctcgcgcaaa atatagtctt
     2581 cgatgacata gggcgaattt aatgtggtta cgccggaaag cccgtaggtt tggcgggggt
     2641 gcggtgcgac atattgtatg ttgaagtttt ttgccgcctt ttccgaaatt tccttcatct
     2701 ccttgtcggg cgaacccaaa agtatccgca ccgtgccgcc cgtttcatcc cccgctttca
     2761 gttcggacgc atcgaacagc ggcaggtaag tcatcttgcg gcggccgtcg tccataatgt
     2821 ttttcaaacc cttgaatatc gtgtaatgct cgtcggaagc attacgggtt ttggcgatac
     2881 tccaatctcc gatcatcatc cgggcaaaat tccgcttgat cgtcccgttt acagaaaact
     2941 catcgcccaa atagctgctg ctttgaatta aattgcctgt cccgtcgtca aaggttttga
     3001 tttccgcatc cgggtaagtg ctcaaaaagg cggcaatgct gactttttcc aaacttgcca
     3061 aataaatccg cttgaccttc ggcagcagca ttgccttcac cttcagctcc gccatcgtcg
     3121 gaatgaaatt aaacgatttg ttcaaaccgt agggcaggtg gaaaaaatac gcccgctccg
     3181 ccttatcctt tatctgattg aaataataat cgtatttttc attcctgttt tcagacatca
     3241 gcaccacata aaaccgctcc cccggatgct gcgccataat cctttccgcc accttcatct
     3301 gcaatatggt atagcagaaa atcagattga ccggttcccc ctcttcattg aagagtttgt
     3361 ccttcagcag ggaaaccgca ttcctttccc cctgatttac ccggtcaaat gtataaaata
     3421 tcccgaaaca aaaaacaatc agacacaaca cggtcaaaca agcctttttc aagcccatat
     3481 ccctaaaact ccattccgac aaattaaaca tacgccccga gtgtcccggg cggaaaaatg
     3541 cggaatttta gcagatattc cgacagttac cgaatattat agtggtttaa atttaaatca
     3601 ggacaaggcg acgaagccgc agacagtaca agcagtacga caaggcgagg caacgctgta
     3661 ctggtttaaa tttaaaccac tataaaatca atttcaccga aaatatgccg ccgcacatca
     3721 ggcacagcac ctccgacacc gccgccaaaa gcgggaaaac catttccccc ttcctttcac
     3781 gccgccgcgt tcaaacacgc caagatcgaa caaagcgcga acaaagccgc caaaatatgc
     3841 cataatagcc acgcacattc cccgcgcaat gtgttccaaa agaaaaaacc aacctacaag
     3901 agaataatcc tatgactcaa aaatccacca ttgtttatac ccataccgac gaagcccccg
     3961 cgctggcgac ccaatcgctg ctgccgattg tgcaggcttt tgcccgccac gccgatattg
     4021 atgtcaaaac tgccgacatt tccctgtccg gccgtatttt ggcggcattc cccgaatatc
     4081 tgaccgaggc gcagcgcgta cccgacgcgc ttgccgaatt gggcgaactg gtaaaacaac
     4141 ccgatgcaaa cgtaatcaaa ctgccgaaca tcagcgcatc cgtacctcaa ctgaccgccg
     4201 cgattaaaga attgcagtct aaaggctttg ccgttcctga ctatcctgcc gaccctcaaa
     4261 ccgatgaaga aaaagccgta cgcgaacgct acgaccgcat caaaggcagc gcggtaaacc
     4321 ctgtcctgcg tgaaggcaac tccgaccgtc gcgcccccaa agcggtgaaa aactttgcca
     4381 aaaaaaatcc gcacagcatg ggcgcatgga caaaagactc caaaacccac gttgccacca
     4441 tgcaaagcgg cgactttttc cataacgaac aatccgttac cgtacctgaa gcgacttccg
     4501 tatccatcgt gttcaccgac aaacaaggca ataaaaaaga gctgcgcgcg cctgttgccc
     4561 tgaaagccgg cgaaatcatc gacgcaaccg tgatgagcaa aaaagccctg ctcgccttcc
     4621 ttgccgaaca agtgaaagac gcgaaggcaa aaggcgtatt gttctcactg catatgaaag
     4681 ccacgatgat gaaagtgtcc gacccgatta tcttcggaca cgccgtcaaa gtgttcttcg
     4741 cgcctgtatt tgaaaaattc ggcggcaaac tggctgccgc aggtgtcaac gtcaacaacg
     4801 gcttcggcaa cctgctggcc aatctggaca aactggatgc ggacacccgc gccgccgtcg
     4861 aagctgaaat cgccgccgtt tacgccgcca accctgattt ggcgatggtt gattccgata
     4921 aaggcattac caacctgcac gttcccagcg atgtcatcgt tgatgcttct atgcctgcga
     4981 tgattcgtaa ctccggccgt atgtgggata aagacggcaa agcgcaagac accaaagccg
     5041 tcattccgga cagcagctat gccggtgttt accaagcaac catcgacttc tgccgcgaac
     5101 acggcgcatt cgatccgaca acaatgggta ctgtgcccaa tgtcggtttg atggcgcaag
     5161 cggcggaaga atacggctca cacaacaaaa cctttgaaat cgaagccgac ggccaagtcc
     5221 aagtcattga tgcggcagga aaagtcctga tgcagcatga cgttgaagca ggcgacattt
     5281 ggcgtatgtg ccaaaccaaa gacgctccgg ttaaagactg ggtgcaactt gccgtcaacc
     5341 gcgcccgtct gagcaacacg cctgccgtgt tctggctcga cgaaaaccgt ccgcacgaca
     5401 agagcctgct cgccaaggtt aaagcctacc ttgccgaact ggataccaat ggcctcgaca
     5461 tccgcgtcct cgctcctgaa gaagccgcca agttcagctt gggtcgtctg aaaaacggcg
     5521 aagatactat ctccgtaacc ggtaacgtcc tgcgcgacta cctgaccgac ttgttcccga
     5581 ttttggaact cggcacaagc gcgaaaatgc tgtctatcgt tccattgatg aacggcggcg
     5641 gtatgtttga aaccggcgcg ggcggttctg caccgaaaca tgttcaacaa ttcctcgaag
     5701 aaaaccacct gcgttgggac tctttgggcg aatttctcgc actcgccgta tcgtttgaac
     5761 atctggcgca aaaaaccggc aacaccaaag cccaagtcct cgccgacact ttggatgcag
     5821 ccaccgaaaa actgctgttg aacgacaaat cgcctaaacg taaagccggc gaactcgaca
     5881 accgcggcag ccatttctac ctcaccctct actgggcgca agaattggcg gcgcaagaca
     5941 aagatgccga actgaaagcc gcatttacgc cattggcagc cgctttgacc gccgacgaag
     6001 cgaaaatcgt tgccgagctt tccgccgtac aaggcaaagc ggccgacatc ggcggctact
     6061 acgccgccaa tcctgaaaaa gccgcacaag tgatgcgtcc gagcgtaacc tttaatcagg
     6121 cactaaacgc cttataagca caaaggtaaa aatgccgtct gaacattcgt cgttcagacg
     6181 gcattagtta tccctatctg cctgattatg attaaacgcc gcacccattg gatataa
//
LOCUS       DAXISH010000088         6188 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.088, whole genome shotgun sequence.
ACCESSION   DAXISH010000088 DAXISH010000000
VERSION     DAXISH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6188
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.088"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            35..1252
                     /locus_tag="ACFOV4_001941"
     CDS             35..1252
                     /locus_tag="ACFOV4_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC7619889.1"
                     /translation="MTHTASKTPKFWLTITAAAFILLITIGMRMTLGLFVQPVVNTTE
                     LSIAQFSLIIAVFQLMWGISQPLSGALADRFGAFRVLSGGAVLLVCACLIAPNIPTYW
                     GLMIAVGLLLAFGTGSGGFSIIMGQVAAQVPAHKRGLASGLVNAGGSTGQFLFAPLVQ
                     GLVVLPEVGWTGTFYVWGAIALLILPVSWWLAGGNNAAHTQHAQATHGQSLGEAVKTA
                     FKTPSYILLHLSFFACGFHIAFLVTHLPTEVALCGLPATVASTAIAIIGLANIAGCVF
                     SGWCTSRVRGKYVLFGLYASRAAMILIYIFSPKTDLNFYIFAAALGFTWLATVTPTAS
                     ITGKLFGTRYLATLFGLTMLSHQIGGFLGSYIGGIVITQFGDYGWMWYADALLAGTAA
                     LLNLPIREPRTAA"
     gene            1249..1380
                     /locus_tag="ACFOV4_001942"
     CDS             1249..1380
                     /locus_tag="ACFOV4_001942"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619890.1"
                     /translation="MKECRLKTLRRHFPNTPPVSGLHDTQISLIKPQTTAAIKPPFK"
     gene            complement(1455..1595)
                     /locus_tag="ACFOV4_001943"
     CDS             complement(1455..1595)
                     /locus_tag="ACFOV4_001943"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619891.1"
                     /translation="MNYRIGNAVCIDEMPDTGRGGQTFAKRTASDASPARAGAASDGI
                     LS"
     gene            1608..2732
                     /locus_tag="ACFOV4_001944"
     CDS             1608..2732
                     /locus_tag="ACFOV4_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFC7619892.1"
                     /translation="MKIVFITTVASSIYGFRAPVIKKLIGKNHQVYAFVSEFSDNELD
                     IIREMGVTPVTYRSNRSGLNPFSDIKSTFLIFKELKKISPDLVFPYFAKPVIFGTFAA
                     KLAGVPRIVGMLEGLGFAFTPQPEGIPLKTKIIKGILIALYHIALPMLESLIVLNPDD
                     KDELTDKYGIKIKNIHILGGIGLDSRQYPYSEADIPDEKEPVKFLFIGRFLKEKGIDD
                     FIRAAEQVKDKYPDTVFTALGAIDKSRGGGDLERLAARDIIRFPGFVNNVSEVIKAHH
                     IFVLPSYREGVPRSTQEAMAVGRAVITTDVPGCRETVADKVNGFLIEPWNPRILAEKM
                     IYFIENREAVRLMGNASYAIAKDKFDAEKVDLKLLDILKA"
     gene            complement(3221..4072)
                     /locus_tag="ACFOV4_001945"
     CDS             complement(3221..4072)
                     /locus_tag="ACFOV4_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma"
                     /protein_id="HFC7619893.1"
                     /translation="MTLLGIKLKQTQQLNQRLQQSLRVLQMSGIELEREVENWLSDNP
                     LLERKDTDEFSDAEFSHYTAPARQIGGDEGEDMLSNIAGEQDFKQYLHAQVCEHPLSD
                     QESACVHILIDFLDEQGYLTDSIEDILDHTPLEWMLDEAMLKQALTALKKFDPAGVAA
                     ADLNESLILQIERSGECAAKPSALHIVRNALDSIDGNRSQTLARIKKRLPQTDSGTLE
                     AALDLIASLNPFPAAGFASSTPTPYSDEALANLLAFRGMEVSRRTIAKYRESFEIPAA
                     HKRKTAE"
     gene            4420..5934
                     /gene="katA"
                     /locus_tag="ACFOV4_001946"
     CDS             4420..5934
                     /gene="katA"
                     /locus_tag="ACFOV4_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase KatA"
                     /protein_id="HFC7619894.1"
                     /translation="MTTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEK
                     LADFVREVIPERRMHAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFTTVAG
                     ERGAADAERDIRGFALKFYTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNM
                     RSATNNWDFWTLLPEALHQVTIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKF
                     HFRTQQGIKNLTNEEAAKIIADDRESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKV
                     PYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQSAFAPSNLVPGIGASPDKM
                     LQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRADGNYGSLPHYEPNSF
                     GQWQQQPDFAEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFGNTAAA
                     MGDAPDFIKYRHIRNCYRCDPAYGEGVAKALGLTVEDAQAARATDPALGQPGLL"
BASE COUNT         1481 a         1790 c         1520 g         1397 t
ORIGIN      
        1 aatccgcaaa cttaaccgac tcaaaataca cattatgacg cacaccgcat cgaaaacacc
       61 caaattttgg ctgaccatca ccgccgccgc attcatcctg ctgattacca tcggcatgag
      121 gatgacgctc ggactgttcg tccaacccgt cgtcaacacc accgaattga gcattgccca
      181 attcagcctc atcatcgccg ttttccaact gatgtggggc atatcgcaac cattgtccgg
      241 cgcgcttgcc gaccgtttcg gcgcgttcag ggtattaagc ggcggcgccg tcctgctcgt
      301 ctgcgcctgc ctgattgccc ccaacatccc gacttattgg gggctgatga ttgccgtcgg
      361 gctgctgctc gcattcggca ccggttccgg cggtttctcc atcattatgg ggcaggtcgc
      421 cgcccaagtc cccgcacaca aacgcggctt ggcatccgga ctggtcaacg ccggcggttc
      481 gacaggacaa ttcctgttcg caccgctggt tcaaggactc gtcgtcctgc ccgaagtcgg
      541 ctggacgggc acattttacg tttggggcgc aatcgccctg ctgattctgc ctgtctcatg
      601 gtggcttgcc ggcggcaaca acgccgccca cacccaacac gcccaagcca cacacggaca
      661 aagcctcgga gaagcagtca aaaccgcctt caaaacccca agctacatcc tgctgcacct
      721 aagctttttt gcctgcggct tccacatcgc ctttctcgta acccacctac ccacggaagt
      781 cgccctgtgc ggactgcccg ccaccgtcgc atccacagcc atcgccatca tcggactggc
      841 aaacatcgcc ggttgtgtgt tctcaggctg gtgcacaagc cgcgttcggg gcaaatacgt
      901 cctgttcgga ctgtacgcct cgcgcgccgc gatgatactc atctacattt tttcgcccaa
      961 gaccgacctc aacttctaca ttttcgccgc cgcactcgga tttacctggc tcgccaccgt
     1021 cacgccgacc gcctccatta ccggcaaact cttcggcaca cgctacctcg ccaccctgtt
     1081 cggactgacg atgctcagcc accaaatcgg cggattcctc ggctcgtaca tcggcggcat
     1141 cgtgattaca caattcggcg actacggctg gatgtggtac gccgacgcac tgctggcggg
     1201 aaccgccgcc ctcctcaacc tccccatccg cgaaccccga accgccgcat gaaagaatgc
     1261 cgtctgaaaa ccctcagacg gcattttcca aacaccccgc ccgtttccgg actgcacgac
     1321 acgcaaatca gccttatcaa accgcaaaca accgccgcga ttaaaccgcc attcaaataa
     1381 gtccgttttc ccttcgggtg taaaatcatc acaaaacgcg atactgtata tcgccgggcg
     1441 ttatgcagcg gatttcagga taaaatgccg tctgaagccg cccctgcccg ggcgggcgaa
     1501 gcgtcggatg cggtgcgctt ggcaaaggtt tgcccgccgc gccccgtatc cggcatttca
     1561 tcaatgcaga ccgcatttcc aatcctataa ttcaaggtgt ccgccttatg aaaatcgttt
     1621 ttatcacaac agtcgcatcc agcatttacg gtttccgcgc ccccgtcatt aaaaaattaa
     1681 tcggcaaaaa ccatcaggtg tatgcctttg tatcggagtt ttccgataat gaattggata
     1741 ttatcaggga aatgggggtt acacccgtta cctaccgttc aaaccgcagc gggctgaacc
     1801 cgttttccga tataaaatcc accttcctca tatttaaaga actcaaaaaa atatcgccgg
     1861 atttggtttt cccttatttc gcaaaacccg tgattttcgg cacttttgcc gcaaaactgg
     1921 caggcgtgcc cagaatcgtc gggatgctgg aaggtttggg attcgcattt accccgcagc
     1981 cggaaggcat accgttaaaa acaaaaatca taaaggggat tttgattgcc ttgtaccaca
     2041 ttgccctgcc gatgttggaa agcctgattg tattaaaccc cgacgacaaa gacgaactga
     2101 cggacaaata cggcatcaaa ataaaaaaca tccatatttt gggcggaatc ggtctggatt
     2161 cgcggcaata tccttattcc gaggcggata ttcccgatga aaaagaaccc gtaaaattcc
     2221 tctttatcgg cagatttctg aaagaaaagg ggattgatga ttttattcgg gcggcggaac
     2281 aggttaagga caaatacccc gatacggttt ttaccgcttt gggcgcaatc gacaaatcac
     2341 gcgggggggg cgatttggaa cggcttgccg cccgcgatat tatccgtttc cccggttttg
     2401 tgaacaatgt ttccgaagtg ataaaggcgc atcatatatt cgtattgccg tcttataggg
     2461 aaggcgttcc ccgaagcact caggaggcaa tggccgtcgg cagggcagtg attacgacgg
     2521 atgtccccgg atgcagggaa acggtcgccg acaaggtcaa cggcttcctg atcgagcctt
     2581 ggaatccccg catcttagcc gaaaaaatga tttattttat cgaaaacagg gaagccgtcc
     2641 gcctgatggg gaatgcaagt tatgcgattg ccaaagataa attcgatgcc gaaaaagtcg
     2701 atttgaaatt gctcgatatt ttgaaggcgt aaacaaggct gcccgctttt gagtttcggt
     2761 catttctgat aaacccccgt cattcccgcc acacccccgt cattccctcg aaagcgggaa
     2821 ttcaggttcg tttagtttcg gtcatttccg ataaattctt gcaactttgc gtttctagat
     2881 tcccactttc gtgggaatga cggcggaggg ttgctgtttt cccgacaaat tcccgccatc
     2941 taaaatctcg ttatccatac aagaaccgaa aatcttgcca ttctcacaaa aacagaaatt
     3001 caaaaacaga aatcccaaac cctcggcatt cccgcgaaag cgggaatcca ggttcgttga
     3061 gtttcggtca tttccgataa attcttgcaa ctttgcgttt ctagattccc tctttcgcgg
     3121 gaatgacggg atgcaggttt ccgcgcggac ggattcggca ttcccgcttt cgcagaaatg
     3181 ccggcttttg gtttgttgtc tttataagat tattcggcaa ttattctgcg gttttgcgtt
     3241 tgtgtgctgc cggaatctca aaggattctc tgtatttggc aatggtgcgg cgagaaacct
     3301 ccatgccgcg gaaagccagc aggttggcga gcgcctcgtc agaatacggc gtgggtgtgg
     3361 acgaggcaaa accggcggcg ggaaagggat tgagcgaagc aatgaggtcg agtgcggctt
     3421 cgagtgtgcc gctgtcggtt tggggcaggc gtttttttat tcgcgcgagg gtttggctgc
     3481 ggttgccgtc aatgctgtcg agggcgtttc ggacgatatg cagggcggag ggtttggcag
     3541 cacattcgcc cgatctttct atctgcagta tcagcgattc gttcaaatcg gcggcggcca
     3601 cgcctgccgg gtcgaatttt ttcaatgcgg tcagggcttg tttcagcatt gcttcatcca
     3661 acatccactc caagggcgta tggtcgagga tgtcttcgat gctgtcggtc agataacctt
     3721 gctcgtcaag gaaatcgatg aggatgtgga cacaggcgga ttcttggtcg gaaagcgggt
     3781 gttcgcatac ttgcgcgtgc aggtattgct tgaaatcctg ctcgccggcg atgttggaca
     3841 gcatatcttc gccttcgtct ccgccgattt gacgggcagg cgcagtgtaa tggctgaact
     3901 cggcatcgga aaattcatcc gtgtctttgc gttcgagcag ggggttgtcc gacagccagt
     3961 tttcgacctc gcgttcaagt tcgatacccg acatctgcaa tacgcgcaaa gattgttgca
     4021 gccgctggtt gagctgctgg gtctgtttga gctttattcc gagtaaggtc atgataatgt
     4081 ggggaaaatt gttattttca gcctgtcggc gcaaaaaatg ccgcaaagcg tcattgcatt
     4141 ataaatggtt ttaatgagcg ggttcggatt ccgttcgata acaaaaaaca aacgaaaatc
     4201 aagaaccgat tgcttataat aatattaaat cgatttcata gttttaatag cgaaaatctt
     4261 ggcgtatagt cgcatccata gtttttacaa aagggaaata aaatgtcgat tcaagaaatt
     4321 tattgcaatc aagaaaccgg ttacgaatac gctttccgcc aaatcgtact gtaagccgtt
     4381 tacccccatt tgaccaacct gagaaaagga acaagagcga tgactacctc caaatgccct
     4441 gtaacccatc tgaccatgaa caacggcgcg cctgttgccg acaatcaaaa cagcctgacc
     4501 gccggtcctc gcggccctct gctggcgcag gatttgtggc tgaatgaaaa actcgccgac
     4561 ttcgtgcgcg aagtcatccc cgaacgccgt atgcacgcca aaggttcggg cgcgttcggt
     4621 acgtttaccg taacgcacga catcaccaaa tacacccgcg ccaaaatctt cagcgaagtc
     4681 ggcaaaaaaa ccgagatgtt cgcccgtttc accaccgtgg caggcgaacg cggcgcagcc
     4741 gatgcagaac gcgacatccg cggttttgcg ttgaagttct ataccgaaga aggcaactgg
     4801 gatgtggtcg gcaacaacac gcccgtgttc ttcctgcgcg acccgcgtaa gttccccgac
     4861 ctgaacaaag ccgtcaaacg cgacccgcgc accaatatgc gctctgccac aaacaactgg
     4921 gacttctgga cgctgctgcc cgaagcactg caccaagtta ccatcgtgat gagcgaccgc
     4981 ggcatccccg ccggctaccg ccatatgcac ggcttcggtt cgcataccta cagcttctgg
     5041 aacgaagcag gcgagcgttt ttgggtgaaa ttccatttcc gcacccaaca aggcattaaa
     5101 aacctgacca acgaagaagc cgccaaaatc atcgccgacg accgcgaaag ccatcagcgc
     5161 gacttatacg aagccatcga acgcggcgag tttccgaaat ggacgatgta catccaagtc
     5221 atgcctgaag cagacgcgga aaaagtacct tatcatccgt ttgacttgac caaagtttgg
     5281 ccgaaaaaag actatccgct gattgaagtg ggcgaattcg agttgaaccg caatcccgaa
     5341 aacttcttcg ccgatgtgga acaatccgcc ttcgcaccga gcaacctcgt tcccggtatc
     5401 ggcgcgagcc cagataaaat gttgcaagcc cgtttgttca attacgccga cgcgcaacgc
     5461 taccgcttgg gcgtgaactt ccgccaaatc cctgtcaacc gtccgcgttg ccctgttcac
     5521 agcaaccagc gcgacggaca aggacgcgcc gacggcaact acggcagcct gccgcactac
     5581 gaacccaata gcttcggcca atggcagcaa caacccgact tcgccgaacc gcctttgaaa
     5641 atcaacggcg acgcggcgca ctgggactac cgccaagacg atgacgacta tttcagccaa
     5701 ccgcgcgccc tgttcaacct gatgaacgac gcgcagaaac aggcattgtt cggcaacacc
     5761 gccgccgcaa tgggcgacgc gcccgacttc atcaaatacc gccatatccg caactgctac
     5821 cgttgcgatc cggcatacgg cgaaggcgtg gcaaaagccc tcggactgac tgtcgaagac
     5881 gcacaagccg cccgcgcgac cgaccccgca ctcggccagc ccggtttgct gtaagggggc
     5941 attatgtgga tggaaattga agaaatcctg tcccgcgccg tccgctaccg gaaataaccg
     6001 ggcataaaaa tgccgtctga aacgtcgttt gaccgcttca gacggcattt ccccatcccg
     6061 cccccgccgt ttcagtgggc gttttttatt aaacgcaaaa tatcccgtca ttcccgcccc
     6121 acagcccact tttccgccgt cattcccgca ccatccccac cggttcaaac cggcacgaaa
     6181 acttttcc
//
LOCUS       DAXISH010000089         6153 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.089, whole genome shotgun sequence.
ACCESSION   DAXISH010000089 DAXISH010000000
VERSION     DAXISH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6153
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.089"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            57..1610
                     /locus_tag="ACFOV4_001947"
     CDS             57..1610
                     /locus_tag="ACFOV4_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid--CoA ligase"
                     /protein_id="HFC7619895.1"
                     /translation="MNRTYANFYGMLAAACRKNGNGTAVFDGKEKTAYRALKQEVEAV
                     AAYLQNIGVKFGDTVALAVSNSTEFITAYFAISAIGAVAVPMNTFLKNSEYAYILNDC
                     KARFLFASVGLSKELAGLKAQTPIEKIIWTGKSRPVGETAEGDAFFEDVRRFPEKPDL
                     GRQPRINDLAHIIYTSGTTGHPKGALISYANLFANLNGIERIFKISKRDRFIVFLPMF
                     HSFTLTAMVLLPIYMACSIILVKSVFPFSNVLKQTLLKRATVFLGIPAIYTAMSKAKI
                     PWYFRWFNRIRLFISGGAPLAEQTILDFKAKFPRAKLLEGYGLSEASPVVAVNTPERQ
                     KARSVGIPLPGLEAKAVDEELVEVPRGEVGELIVRGGSVMRGYLNMPAATDETIVNGW
                     LKTGDFVTIDEDGFIFIVDRKKDLIISKGQNVYPREIEEEIYKLDAVEAAAVIGVKDR
                     YADEEIVAFVQLKEGMDLGENEIRRHLRTVLANFKIPKQIHFKDGLPRNATGKVLKRV
                     LKEQFDGNK"
     gene            complement(1700..3727)
                     /locus_tag="ACFOV4_001948"
     CDS             complement(1700..3727)
                     /locus_tag="ACFOV4_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HFC7619896.1"
                     /translation="MSLSEFIERRTSFNPMVILTTLFFVCVLAVLVLTVPDQVQMWLD
                     RAKEVIFTEFGWFYVLTFSIFLGFLLILSVSSLGNIRLGRDEDVPEFGFLSWLAMLFA
                     AGMGVGLMFFGVAEPLMHYFSDITAGTPEHRQQQALLHTVFHWGVHAWSVYGTIALAL
                     AYFGFRYKLPLALRSCFYPLLKEKISGRFGDAIDIMALLATFFGIITTLGFGASQLGA
                     GLQEMGWIAENSFSVQVLIIAAVMSLAVVSAISGVGKGVKVLSELNLSLAFLLLFFVL
                     AAGPTVYLLSAFGDNIGNYLENLVRLSFKTYAYEREHKPWFESWTVLYWAWWCSWAPF
                     VGLFIARISKGRTIREFVFGVLLIPGLFGVLWFTVFGNTAIWLNDGVAGGMLEKMTSS
                     PETLLFKFFNYLPLPELTSIVSLLVISLFFVTSADSGIYVLNNITSRDKGLSAPRWQA
                     VMWGVLMSAVAVLLMRSGGLGNLQSMTLIVSLPFALLMLIMCFSLWKGLSADKKYFET
                     RVNPTSVFWTGGKWKERLVQIMSQTQEQDILKFLKHTASPAMHELQRELSEEYGLSVR
                     VDKMFHQDEPAIEFVIRKETMRDFMYGIKSVGQDVSDQLINDGNLPHIRHQTTYKPYA
                     YFFDGRVGYDVQYMNKDELIADILKNYERYLMLLDDVGQELMAHEQVELAE"
     gene            4016..6022
                     /locus_tag="ACFOV4_001949"
     CDS             4016..6022
                     /locus_tag="ACFOV4_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HFC7619897.1"
                     /translation="MADMKKITPQNLRPLLSESLGHTDFVNVLNALIKFLRRGGKKCA
                     GERFDLIIDTFKQDRELLSRFSRCFYIWLAQIHIYPALIKLGIFSRHSFAREMGIRIY
                     ERFSPSYKDFANLGEVFLYLFHSENDDKWLQTLNIRQWLVLYELIRSHAEPSKLQTAG
                     IRLADARLRAIEMLSVWTASEAIEPDLIRIAPRLLEADSSFVALQRETAKLVEHYRNG
                     TAPYDTAHLEVMFDQCFSQIDYLRRKGTGAGSGSSVKVAHLLERLRQTVGRLKLLTDI
                     QTGVGNSNRLTIALMNSLIYAAVEQYSTRHLRRSSIRMLARSITENKSHHGEHYITRN
                     RKEYFKMFYSAAGGGIIIALMALLKIRIGSLGLSPFLTSLSAGFNYGIGFMIIHMLHC
                     TVATKQPAMTAASFAEQVDLNEGGKAVDNKLAKLLIDVCRSQSVAVFGNVSIAILLAC
                     AISFGYAHLYRLPILDAHTAAYQFKSIDIIAYPTLWYAAIAGLWLFCSGIIAGFFDNR
                     ADYLNLRQRLPFNPLLRKIMRPGPRRVLAAYIHKHYGSLAGNFIFGMLLGMTGYFGHL
                     LGLPLDIRHVAFSSANLGYAAVSGNVGLGTFVLGIFSVLAIGLVNLCVSFSLALFVAL
                     RSRGTKIGSIRNLIKSFWNQIKSNPCILFLPPAKEQGHPPSDKP"
BASE COUNT         1565 a         1871 c         1442 g         1275 t
ORIGIN      
        1 cggcatattg ttttcaaatg agggcgttcg ccgtccgcaa ccataaagga agtttcatga
       61 accggactta tgccaatttc tacggaatgc tcgccgccgc ctgccgcaaa aacggcaacg
      121 gcacggcagt gttcgacggc aaggaaaaaa ccgcctaccg cgcgctcaag caggaggtcg
      181 aagccgtcgc ggcgtatctg caaaatatcg gcgtgaagtt cggcgacacg gtcgcgctgg
      241 cggtttccaa ttccacagaa tttattaccg cctatttcgc catctccgcc atcggcgcgg
      301 tcgccgtacc gatgaacaca tttttgaaaa acagcgaata cgcgtatatc ctgaacgact
      361 gcaaggcgcg cttcctgttc gcctcggtcg gcctgtcaaa agaattggcg ggcttgaagg
      421 cgcaaacgcc catcgaaaaa atcatttgga cgggcaaaag ccggccggtc ggcgaaacgg
      481 cggaaggcga tgcctttttt gaagacgtgc gccgcttccc cgaaaaaccc gacttgggcc
      541 gacaaccccg gataaatgat ttggcacaca tcatctacac ctccggcacg acggggcatc
      601 ccaaaggcgc actaatcagt tacgccaacc tgttcgccaa cctgaacggc atcgaacgca
      661 tctttaaaat ttccaaacgc gaccgcttta tcgttttcct gccgatgttc cacagcttca
      721 cgctgacggc tatggtgctg ctgccgattt atatggcgtg ttcgattatt ttggtcaaat
      781 ccgttttccc gttttccaat gttttgaaac agaccctgct caaacgcgcg accgtgtttt
      841 tgggcatacc cgcgatttac accgcgatga gcaaggcgaa aatcccttgg tatttcagat
      901 ggttcaaccg cattcgcctg tttatcagcg gcggcgcgcc tttggcggaa caaaccatcc
      961 tcgatttcaa agccaagttc ccccgcgcca aattgctgga aggctacgga ctgagcgaag
     1021 cctctcccgt cgtcgccgtc aatacgcccg agaggcaaaa agcccgcagc gtcggcatcc
     1081 ccctgcccgg tttggaagcc aaagccgtcg atgaagaatt ggtcgaagtg ccgcgcggcg
     1141 aagtgggcga actgatcgtc aggggcggtt cggtgatgcg gggctacctc aatatgcctg
     1201 ccgccaccga tgaaaccatc gtcaacggct ggttgaaaac gggcgatttc gttaccatag
     1261 acgaagacgg ctttatcttt atcgtcgacc gcaaaaaaga tttgattatt tccaaaggtc
     1321 aaaatgtcta tccgcgcgag attgaagaag aaatctacaa actcgatgcc gtcgaagccg
     1381 ccgccgtcat cggcgtgaaa gaccgttatg ccgacgagga aatcgtcgcc ttcgtccaat
     1441 tgaaggaagg tatggatttg ggcgagaacg aaatccgccg ccacctgcgt accgtgctgg
     1501 caaatttcaa aatccccaaa caaatccact ttaaagacgg gctgccgcgc aacgctacgg
     1561 gcaaggtatt gaaacgggtg ttgaaggagc agtttgacgg aaacaaatga acgccgtgcc
     1621 gtccgaagcc ccgtccggca aaaaaaatgc ggtgaatctg cttcaccgca ttttttggca
     1681 aacgccggag cgaggatatt tactctgcca attccacctg ctcgtgcgcc atcagttcct
     1741 gaccgacatc atccaacaac atcaaataac gttcgtagtt tttcaaaatg tcggcaatca
     1801 gctcgtcctt gttcatatac tgcacatcgt acccgacgcg cccgtcgaaa aaataagcgt
     1861 agggtttgta agttgtctga tgccggatat gcggcaggtt gccgtcgtta atcaactggt
     1921 cggatacatc ctgcccgaca gacttaatcc cgtacataaa atcgcgcatc gtctctttcc
     1981 gaatgacgaa ctcgattgcg ggctcgtcct gatgaaacat cttatcgacc cggacgctca
     2041 agccgtattc ttccgaaagc tcccgttgca actcgtgcat agcgggcgat gcggtatgtt
     2101 tgaggaattt taaaatatcc tgctcctgcg tctggctcat tatctgcacc agccgttctt
     2161 tccacttgcc gcccgtccaa aatacactgg tagggttaac ccgggtctca aaatatttct
     2221 tatccgcact caatcctttc cacaggctga aacacattat cagcatcagc agggcaaacg
     2281 gcagggaaac aatcagggtc atagactgca ggttgcctag cccgcccgag cgcatcagca
     2341 aaacggcaac ggcagacatc agcacgcccc acataaccgc ctgccaccgt ggtgcgctca
     2401 agcccttgtc ccgagaggta atattgttca ggacataaat cccggaatcg gcagaagtta
     2461 caaaaaacag ggaaatgacc agcaggctga cgatgctcgt caattcgggc agggggaggt
     2521 aattaaagaa tttaaaaagc agcgtttccg gagaggaggt catcttttcg agcattcccc
     2581 ccgcaacccc gtcattcagc caaatcgccg tattgccgaa gacggtaaac cacaaaacgc
     2641 cgaacaggcc ggggatgagc aaaaccccga agacaaactc gcggatggtg cgcccctttg
     2701 aaatacgcgc gataaacaaa cccacaaacg gcgcccaaga acaccaccac gcccaataaa
     2761 gcaccgtcca agattcaaac cacggcttgt gttcccgttc gtacgcataa gttttaaaac
     2821 tgaggcgcac cagattttcg aggtagttcc ctatgttgtc gccgaatgcc gacaacaggt
     2881 aaacagtggg gcccgccgcc aaaacaaaaa acagcagcaa aaacgcaagg ctcaggttca
     2941 actcgctcaa caccttcacg cccttcccca cgccggatat tgccgaaacg acggcgaggg
     3001 acatgacggc ggcgataatc aaaacctgca cgctgaagct gttttcggca atccagccca
     3061 tttcctgcaa tccggcgccc agttgcgaag ccccgaaccc caatgtggtg atgatgccga
     3121 aaaaagtagc aagcaacgcc ataatatcaa tggcatcgcc gaaccttccg gaaatttttt
     3181 ctttcaacag ggggtaaaaa caagaacgca gggcaagcgg cagcttgtag cggaaaccga
     3241 aataagccaa agccaatgca atcgtaccgt acaccgacca agcgtgaacg ccccaatgga
     3301 acaccgtgtg cagcaatgcc tgctgctgcc tgtgttccgg cgtgccggcc gtaatgtccg
     3361 aaaaataatg catcaacggc tctgccacgc cgaaaaacat cagacccacg cccatcccgg
     3421 ccgcaaacag catcgccagc cacgacagga agccgaattc cggcacatct tcatcccgtc
     3481 cgagcctgat gtttcccaaa ctgctgaccg agagtatcag caggaaaccc agaaaaatgg
     3541 aaaacgttaa aacataaaac cagccgaact cggtaaaaat gacttctttt gcccgatcga
     3601 gccacatctg cacctgatcc ggcacggtta aaaccaatac cgccaaaaca cacacaaaaa
     3661 acaaagtcgt caaaataacc atcggattaa atgacgttcg gcgttctata aattcagaca
     3721 gggacaaacc ttctcactcc tttgttaaaa acagacaaac ccggtcatcg ggcaaagcgg
     3781 tcaaaacctg ccggtaaaat accggcttcc ggatgacgaa atgcacaaac cggccgaaat
     3841 tgttataatc gaaaaaatta aaaatcaata cggattattc tatcagattg atttatcgat
     3901 atttattata tcattaatat agtttgattt caaaccggcg gaaaatgcgc cgcccaccgc
     3961 aggcgcgccc tccccgctat cggggcgttt aacgccggat tgccgatgcg gtacaatggc
     4021 tgatatgaag aaaattaccc ctcaaaacct gcgccccctg ctttcggaaa gcttgggaca
     4081 taccgatttt gtcaacgtcc tcaacgcact gattaaattt ttgcgccgtg gcggcaaaaa
     4141 atgtgcgggg gaacgtttcg acctgattat cgacacattc aaacaagaca gggaattact
     4201 gtcccgcttc agccggtgtt tttacatctg gctcgcgcaa atacacattt atccggcact
     4261 catcaaactc ggcatcttct cgcgccacag ctttgcccgg gaaatgggca tacgcatcta
     4321 cgaacgcttc agcccgtcat ataaagattt tgccaacttg ggcgaagtct tcctttatct
     4381 tttccattcc gaaaacgacg acaaatggct gcaaacgctc aatatccgcc aatggctggt
     4441 tttatacgaa ctcatccgga gccacgccga gccgtccaaa ttgcagacgg cgggcatccg
     4501 ccttgccgat gcgcgtttgc gcgccatcga aatgctgtct gtctggacgg catccgaagc
     4561 catcgaaccc gacctcatcc gcatcgcccc gcgcctgctg gaggccgatt cttccttcgt
     4621 cgccctccaa cgcgaaaccg ccaaactggt cgaacactac cgcaacggca ccgcgcctta
     4681 cgacaccgcc cacctcgaag tgatgttcga ccaatgtttc agccagattg actatttgcg
     4741 ccgcaaaggg acgggcgcag gctccggttc gtcggtcaaa gtcgcccacc tgctcgaacg
     4801 gctccggcaa accgtaggcc gtctgaagct gcttaccgac atccaaaccg gtgttggcaa
     4861 cagcaaccgc ctgaccatcg cgctgatgaa ctccctcatc tacgcggcag tcgaacaata
     4921 cagcacccgc cacctgcgcc gcagcagcat ccgtatgctc gcccgcagca ttaccgaaaa
     4981 caaaagccac cacggcgaac actacatcac ccgcaaccgc aaagaatatt tcaaaatgtt
     5041 ctactcggcg gcaggcggcg gcatcatcat cgccctgatg gcgctgctca aaatccgcat
     5101 cggctcactc ggcctcagcc ccttcctcac ttccttgtcg gctgggttca actacggcat
     5161 cggctttatg atcatccata tgctgcactg caccgtcgcc accaagcagc ccgcgatgac
     5221 tgccgccagc tttgccgaac aggtcgatct caacgaaggc ggcaaagcgg tggacaacaa
     5281 actcgccaag ctcctcatcg acgtatgccg ctcccaaagt gtcgccgtct tcggcaacgt
     5341 ttccatcgcc atccttttgg cgtgcgccat atcgttcggc tatgcccatc tgtaccggct
     5401 gcccatactc gatgcccaca ccgccgccta ccagttcaaa tccatagaca tcatcgctta
     5461 cccgacgctg tggtatgccg ccattgcagg tctgtggctg ttctgctccg gcatcatcgc
     5521 aggttttttc gacaaccgcg ccgactacct caacctgcgc caacgcctgc ccttcaaccc
     5581 cttgctgcgt aaaatcatgc gccccgggcc ccgccgcgtc ctcgccgcct acatccacaa
     5641 acactacggc tcgttggcag gcaacttcat cttcgggatg ctcttgggta tgaccggcta
     5701 tttcggacac ctcctcgggc tgccgctgga catccgccac gtcgcctttt cctccgccaa
     5761 cctcggctat gccgccgtca gcggcaacgt cggtttgggc acgttcgtac tcggcatttt
     5821 cagcgtcctc gccatcggcc tggtcaacct ctgcgtcagc ttcagcctcg ccctcttcgt
     5881 cgccctgcgc tcgcgcggca cgaaaatcgg cagcatccgc aatctgatta agagtttttg
     5941 gaatcagatt aaaagcaatc cctgcatact tttcctcccg cccgccaaag aacagggaca
     6001 tcctccttcg gacaagcctt gaccggcaat gccgtctgaa gcgggattcg ccccgaatac
     6061 cgccctgatg cgggattcgc cccgaatacc gccctgatgc gggaaatccc cataaaagga
     6121 tgagaccttt gcaaaaatag tctgttaacg aaa
//
LOCUS       DAXISH010000090         6075 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.090, whole genome shotgun sequence.
ACCESSION   DAXISH010000090 DAXISH010000000
VERSION     DAXISH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6075
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.090"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(204..2291)
                     /locus_tag="ACFOV4_001950"
     CDS             complement(204..2291)
                     /locus_tag="ACFOV4_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003700725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HFC7619898.1"
                     /translation="MDYLSRLSFGFNKKLPVILQTEVAECGLACLTSILSYYGFHTDL
                     RTLRQKYTLSLKGANLADIMRFGNEMNLTPRALRLELDELSNLQLPCILHWNLNHFVV
                     LCSISKDSIVIMDPAVGMRKIKMDEVSQKFTGIALELFPNTHFEEKKETKKIKILSLL
                     RGISGLKRSLIQMLILAISLEVFALVSPFFMQWVIDHVIVTADKNLLLTLTLGFGLLA
                     ILQQLISLLQAWVGMHLSTTLNLQWKANIFKRLLDLPNDYFSKRHLGDVISRFGSIDH
                     IQETLTSTFFVLVLNSLMAVFTFVLMTIYSTQLSLIVLLTLVLYILIRWLAYYPLRNA
                     TEENIVHEAKQNSYFMETIRGIQSVKLFDKHYQRHGTWMSLFVNTVNTKLTTDKLSAL
                     FEFSNKLLFSMENIIIIYLGASAILDGSFTVGVLMAFLAYKGQFESRTASLVDQYIQI
                     KMLGLHAERLADITLNETETEIIKYNHIPKLDNEQLVLKVENVSFRYADNEPYLFENI
                     NLEFKDNEAVVLTGQSGRGKSTLLNILTGSLKPETGTVSINGHDIYQVSPSFIRGLSG
                     IVRQDDVLFAGSIGENISFFDESPNMELIEQCAKMAQIHDDILKMPMGYETLIGDMGN
                     ILSGGQKQRVILARALYKRPKILFLDEASSHLDVENEQKINHNLKSLGIMKIMVAHRQ
                     ETIQSADKILNLG"
     gene            complement(2294..3559)
                     /locus_tag="ACFOV4_001951"
     CDS             complement(2294..3559)
                     /locus_tag="ACFOV4_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HFC7619899.1"
                     /translation="MSHLFRKEVFVAQQNKWTGQVILTRPFSFLFLTFCAFLIALCII
                     IFLIFGSYTNKTTVEGQLLPTMGVVRVYSSDIGTITHKFVEDGNFVKAGEPLFKLSTS
                     RFGEKGNVQAKLAAEANLKKTLALQELERLKRIHQNEQKNVHNNIHRLNNQLENIKQQ
                     ITGQNRQIRLAEKTLNKNKFLASQGAVSQQDKMTAESHLLEQRSRLESLKLEQNNAIR
                     ELDEQKITLSSLPERHKTELSQLNRAITEMNQEILDFDLKSEQTIRASKSGYISTINV
                     DIGQQVEPSKLLLSIVPEQTELVANLYIPSKAVGFIKPKDKVVLRYQAYPYQKFGHAT
                     GEIISVARTALGKQELSGLGIIFTNPTLLNEPAYLVKVKLEKQTIKAYGENKPLQIGM
                     ILEADILHERKKLYEWVLDPLYSISGKIN"
     gene            complement(3603..3740)
                     /locus_tag="ACFOV4_001952"
     CDS             complement(3603..3740)
                     /locus_tag="ACFOV4_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619900.1"
                     /translation="MNTETIYATVFCILAATISGLLVKFNVIKIETSINSKFMLLGIS
                     I"
     gene            complement(4780..5016)
                     /locus_tag="ACFOV4_001953"
     CDS             complement(4780..5016)
                     /locus_tag="ACFOV4_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HFC7619901.1"
                     /translation="MKELHTSELVEVSGGKFHIFAQGGGNLGKKDMVAVGKIGASYSP
                     NNSGVEFSVSKQFGYVQGLGVQFSKPTFGISKKW"
BASE COUNT         1934 a         1080 c         1039 g         2022 t
ORIGIN      
        1 ccgtgaaatt agcccaaaaa tgggaacaag agcagaaaaa acaacaaatt caacagaaaa
       61 aggaaactga aaaatcgcca aaacacaaag ccagtcgtga tgattgggaa atggaacgtt
      121 aaaccgctat tttcatgtat tctattaaat tatttaaaaa aagacttcac tttttgttaa
      181 agaaaaatga agtcttgttc tgttcaacct aaattcagaa ttttatctgc cgattgaatt
      241 gtttcttggc ggtgtgcaac cattattttc ataataccaa gactttttag gttatggtta
      301 attttttgtt cattttctac atctaaatgg ctacttgctt cgtctaaaaa tagaattttg
      361 ggtcgtttat acaatgcacg agccaagata actctctgct tttgtccacc tgataagata
      421 tttcccatat cgccaatcaa ggtctcatag cccattggca ttttaagtat atcgtcatgt
      481 atttgtgcca tttttgcaca ttgttcaatg agctccatat ttgggctttc atcaaaaaat
      541 gaaatatttt ccccaataga acctgcaaaa aggacatcat cttggcgaac aatcccgctc
      601 aatcccctaa taaaggatgg agaaacttga tatatatcat gcccattaat actaactgta
      661 ccagtttcag gttttaggct acctgttaaa atgtttaaca aagtggactt cccccgacca
      721 gattgtcctg ttaaaacaac tgcttcatta tctttaaatt ccaaattaat gttttcaaaa
      781 agatatggct cattatcagc atatctgaat gagacgtttt caactttaag aaccagttgt
      841 tcattatcta atttaggtat atgattatac ttaataattt cagtttctgt ttcatttaaa
      901 gtaatgtcag ccaaacgttc agcatgaagc cctaacattt tgatttggat gtattggtca
      961 acgagagaag ctgttctgct ttcaaattgc cctttataag ccaaaaaagc catcagaaca
     1021 ccgactgtaa atgaaccatc taaaattgcg cttgcaccaa gataaattat gataatattt
     1081 tccatgctaa acaacagttt atttgaaaat tcaaataaag cagagagttt atctgttgtc
     1141 agcttggtat tgactgtatt cacaaatagg ctcatccaag tgccatgtct ttgataatgt
     1201 ttatcaaata atttaactga ttggatacca cgaatggttt ccatgaaata tgagttttgt
     1261 ttggcttcat gaacaatatt ttcttctgtt gcatttctta atgggtaata tgcaagccaa
     1321 cgaattagta tgtacaaaac aagtgttaaa agaacaatca gcgataattg agtgctgtaa
     1381 attgtcatta acacgaaagt aaaaacagcc attaagctat ttaaaactaa aacaaaaaaa
     1441 gtagaagtta gtgtttcttg gatatgatct attgaaccaa atcttgaaat cacatctcct
     1501 aaatgtcgtt tactgaaata gtcattaggt aagtcaagta accttttaaa tatattggct
     1561 ttccattgta aattaagagt tgtagatagg tgcataccta cccatgcttg taacaggcta
     1621 attaactgtt gcaggatagc cagtaaacca aatcccaaag taagggtcag taataaattt
     1681 ttatcagcag ttacaatgac atggtctatt acccattgca taaagaatgg actaaccaat
     1741 gcaaagactt ccaaagaaat agctaatata agcatttgaa ttaaagagcg ttttaagcct
     1801 gaaatccccc ttaatagaga taatattttg attttctttg tttctttttt ctcttcaaaa
     1861 tgggtattgg ggaataattc tagggcaatc cctgtgaatt tttgtgaaac ttcgtccatt
     1921 ttgatttttc gcataccgac agcagggtcc ataatgacga tactgtcttt ggaaatggaa
     1981 caaagtacaa caaaatggtt taagttccaa tggagaatgc agggtagttg taaatttgac
     2041 agctcatcta actctaaacg caaagctcgt ggcgttaaat tcatttcatt gccaaatctc
     2101 atgatgtctg caagatttgc gccctttaat gacagggtgt atttttggcg taacgttctt
     2161 aaatcagtgt gaaagccata ataggacaag atggatgtca ggcatgctaa accacattca
     2221 gcaacttctg tttgcagaat gacaggtagc tttttgttaa atccaaagga cagtcttgat
     2281 aaataatcca tttttaattg atttttcctg aaatgctgta aagtgggtca agtacccatt
     2341 cgtacaattt ttttcgttca tggagaatat ctgcttctaa aatcatgcca atttgaagcg
     2401 gcttgttttc tccgtatgct ttaatcgttt gtttttccaa tttaactttc acaagatagg
     2461 caggttcatt taataaggtt gggttagtga aaatgatacc taaacctgat agctcttgtt
     2521 taccgagagc agttctggca actgaaataa tttctcctgt ggcatgtcca aatttttggt
     2581 aagggtacgc ttggtaacgt aaaacaactt tatctttcgg tttaataaaa ccaacagctt
     2641 tactgggtat gtaaagattg gcgaccaatt cagtttgttc agggacaatg cttaacagca
     2701 atttagacgg ttcaacttgt tgccctatat caacattaat tgttgatata taacctgatt
     2761 tactagctcg tatggtttgt tcggatttca aatcaaaatc caaaatttct tggttcattt
     2821 ccgtaatcgc acggttgagt tggctcaatt cggttttatg gcgttcaggc aggctgctta
     2881 atgtaatttt ctgttcatca agttccctga ttgcattatt ttgttcaagt tttaggctct
     2941 ccaaacgtga gcgttgttcc aataaatggc tttcggcggt catcttatct tgttgggata
     3001 ctgcgccttg actggctaaa aacttgttct tgttaagggt tttttccgct aaacgaattt
     3061 gacgattttg ccctgtaatt tgctgtttaa tattctctaa ttgattgttt aaacgatgaa
     3121 tgttgttatg aacatttttt tgctcatttt gatgaatgcg ctttaaacgt tccaattctt
     3181 gtaatgccaa agttttttta aggttggctt ctgctgccaa tttggcttgt acgtttcctt
     3241 tttcgccaaa acgcgatgtg gaaagtttga acaatggttc gccagctttg acaaagttac
     3301 catcttcaac aaatttatgc gtaatcgtgc cgatatcgga agagtaaaca cgaaccaccc
     3361 ccatagttgg aagtaattga ccttcaacgg ttgttttatt ggtatagcta ccaaaaatca
     3421 aaaagataat gatacacaga gcaatgagaa aagcgcaaaa agtcagaaat aaaaaagaga
     3481 atggacgggt caagataacc tgacctgtcc acttattttg ttgggctaca aagacttctt
     3541 ttcggaataa gtgggacatt tattattatt tcttaaaaaa atggatagaa aaacaccaat
     3601 aattaaatac ttatgcctaa taacataaat ttgctattga ttgatgtttc tattttaatt
     3661 acattaaatt taaccaataa tccagaaatg gttgcagcta aaatgcaaaa gacagtggcg
     3721 taaatggttt cagtattcat aatttttctc tttcaaaatt gttcaatcta aatagaaaaa
     3781 ggtaacttca atacatattg ctgtaactga aattaccttt tccttaatga tgtaattatc
     3841 ttatggcttc atcatgccac gaccgatatt gtatccgcca gcagcagaga aaataccagc
     3901 tccaattgcg ccaacccagc ctactggtcc tgtccacttg ttccgttgag ctacaaagac
     3961 ttctggtctg aaaaatgagt gattgttaga catgtgtact tatttatgtt tctttgattg
     4021 ggataaattt gtaaaaacaa aaaaaaggca agttgttatt atagaagaac ttaaaatgct
     4081 taacatactc attgaggttt gtaccacata atgagatacg agataatttg ttgggagtaa
     4141 aatcaaaaaa agattaaata tttaaaataa tcactatatt ttttcattat ttgttccttt
     4201 ttgtatttaa gttcttatga aaaactaggg tattttgaat agaaaatatc aaaataccct
     4261 agttttatta aggaatatta ccaccaacaa gtgcttccat attgtacagc accagtgatt
     4321 gcaccaccaa tagctccgaa tttcgcacct ggaatagcac caataccacc tgcaaatgaa
     4381 ccaacaattg ccccaccagc tgctccacct aatgcactac caatggtatt ttttgagaaa
     4441 tcacgccagt tacaagcagc accagaaact tattgaattt cattcaaagt caaaacttgc
     4501 ataatattca cctttgttaa gtgtggttga gaaaaaagta aattttcatc gttactcatt
     4561 atttgcaatc atgcatatac tgtaaccaag cactatattc agttggatta tagtttttcc
     4621 tactgggttg tctgatatga ctattggcac tattggcaca attgggatta gcaactttat
     4681 tgtgagtacc taatggattg atatttcctg taaagtggct attgcatgcg cttaatgagc
     4741 atagatttat taatgtcaga aaggataaaa caaaaaatct taccattttt tactaatacc
     4801 aaaagtaggt ttcgaaaact gtacaccaag accttgtaca tatccaaatt gcttgctaac
     4861 agaaaactct actccactat tgttagggga ataggaagca ccaattttac caacagcaac
     4921 catatctttt ttacctaggt tgccgccacc ctgtgcaaag atatggaatt tgccacctga
     4981 cacttcaact aattcagagg tgtgtaactc tttcatgatt ttctcctgta aagaagtatg
     5041 gttggaaatg taaatcagaa ttaacctttc ttaagtttaa tttaatactt tttttgcaag
     5101 tattttattt taaattaaat caatatttta aaaatattta cttgtatact gaatatttac
     5161 ttgtatactg aaaaagaaac tcctaatggt ggagtggggc ttttgtttaa gtaagcattg
     5221 aaaaaattta aatttcccat tatgattaac ttaatgcaag agctttttca ggacgtacaa
     5281 accagcgaac gggcgttctg atgtgggcag gttggttgtc gctaaccaat ttcagtagct
     5341 caatcgtcag attggtatcc ggccctatca agctaaggag aggctgcggc tactacacaa
     5401 agcacctgaa attattgggt gcttttgtct ttttatggca ttgtaccaat ttgtgtacca
     5461 cgagggcttg ttcgcccaaa cgcggtaaca actgaataca cactttcccc ctcaacttct
     5521 ttgcgttcta aaacgactgt cccaatccga gaatagacaa tcataggacg atgattgccc
     5581 cttacatcac taaattcact aaaaattttt gcgcctgatt gaaaaatcat ttccacataa
     5641 aagggttaca cctgtttcat cgtggcttaa tccaaaccgc gttaaatctg ctttgtgttc
     5701 tgccaaaatg tgaatcacac caaagccgtg attaaccttt ttgtgttcgc cgtgttttaa
     5761 aacaatttga cctgccgaga agtctgctct attgttcgga caataggggg aatataccaa
     5821 ttactttaac tacatcattt tttgacattt ttcttgcctt tcaatttaaa atccaaaatc
     5881 atactgccat aatttagcaa tccaaaaaaa tttaggcagc agtcatggtt tcgtatttta
     5941 gaaaacgaaa cttggtttgg tgttttgaag catttcagta cacaaacatg gaattttaaa
     6001 ttgtcttgtg ttgccttgat ttaggatgtt ccagtttttt aataaatagt ttggggctgt
     6061 cctagataac tagga
//
LOCUS       DAXISH010000091         5992 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.091, whole genome shotgun sequence.
ACCESSION   DAXISH010000091 DAXISH010000000
VERSION     DAXISH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5992
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.091"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..413)
                     /locus_tag="ACFOV4_001954"
     CDS             complement(<1..413)
                     /locus_tag="ACFOV4_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HFC7619902.1"
                     /translation="MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARC
                     GLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINAASQQELEALPGIGPAKAKAIAE
                     YRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGA"
     gene            complement(449..562)
                     /gene="rrf"
                     /locus_tag="ACFOV4_001955"
     rRNA            complement(449..562)
                     /gene="rrf"
                     /locus_tag="ACFOV4_001955"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(659..3550)
                     /locus_tag="ACFOV4_001956"
     rRNA            complement(659..3550)
                     /locus_tag="ACFOV4_001956"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(3956..4031)
                     /locus_tag="ACFOV4_001957"
     tRNA            complement(3956..4031)
                     /locus_tag="ACFOV4_001957"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3996..3998),aa:Ala,seq:tgc)
     gene            complement(4037..4113)
                     /locus_tag="ACFOV4_001958"
     tRNA            complement(4037..4113)
                     /locus_tag="ACFOV4_001958"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4077..4079),aa:Ile,seq:gat)
     gene            complement(4215..5755)
                     /locus_tag="ACFOV4_001959"
     rRNA            complement(4215..5755)
                     /locus_tag="ACFOV4_001959"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         1304 a         1757 c         1283 g         1648 t
ORIGIN      
        1 gcgccgaccg aagcctgatc cttcagcttc gccagcaccg cagggccgat gccctttacc
       61 ttggtcaaat cgtccacaga cttgaacgca ccgttttgcg cacggtattc cgcaatggcc
      121 ttcgccttcg cagggcctat gcccggcagc gcctccaact cctgctgcga agccgcattg
      181 atgtttaccg ccgcaaggga gaaggcgcag gagaacagca tacagaacag cacgaacatt
      241 ttcttcatgg tttttccttt aagggttgca aacaataaac cgcatcttgc gacgataaaa
      301 cgagtcattc taaaatgaat atcccaaagt ttcaagccgt tcctccgcaa acccgaccgg
      361 acgccgtacg gatactgtcc cgccatcccc gacatttttt ccgggcaaag caaaaacccc
      421 cgaataatcg ggggttttct gaaagggtgt ttggcagtga cctactttcg catggaagaa
      481 ccacactatc atcggcgctg agtcgtttca cggtcctgtt cgggatggga aggcgtggga
      541 ccaactcgct atggccgcca aacttaaact gttacaaatc ggtaaagcct taatcaatat
      601 attcggtaat gactgaatca gtcagtaagc ttttatctct tgaagttctt caaatgatag
      661 agtcaagcct cacgagcaat tagtatgggt tagcttcacg cgttaccgcg cttccacacc
      721 ccacctatca acgtcctggt ctcgaacgac tctttagtgc ggttaaaccg caagggaagt
      781 ctcatcttca ggcgagtttc gcgcttagat gctttcagcg cttatctctt ccgaacttag
      841 ctacccggct atgcaactgg cgttacaacc ggtacaccag aggttcgtcc actccggtcc
      901 tctcgtacta ggagcagccc ccgtcaaact tccaacgccc actgcagata gggaccaaac
      961 tgtctcacga cgttttaaac ccagctcacg taccacttta aatggcgaac agccataccc
     1021 ttgggaccga ctacagcccc aggatgtgat gagccgacat cgaggtgcca aactccgccg
     1081 tcgatatgaa ctcttgggcg gaatcagcct gttatccccg gagtaccttt tatccgttga
     1141 gcgatggccc ttccatacag aaccaccgga tcactatgtc ctgctttcgc acctgctcga
     1201 cttgtcggtc tcgcagttaa gctacctttt gccattgcac tatcagtccg atttccgacc
     1261 ggacctaggt aaccttcgaa ctcctccgtt acgctttggg aggagaccgc cccagtcaaa
     1321 ctgcctacca tgcacggtcc ccgacccgga tgacgggtct gggttagaac ctcaaagaca
     1381 ccagggtggt atttcaagga cggctccaca gagactggcg tctctgcttc aaagcctccc
     1441 acctatccta cacaagtgac ttcaaagtcc aatgcaaagc tacagtaaag gttcacgggg
     1501 tctttccgtc tagcagcggg tagattgcat cttcacaacc acttcaactt cgctgagtct
     1561 caggaggaga cagtgtggcc atcgttacgc cattcgtgcg ggtcggaact tacccgacaa
     1621 ggaatttcgc taccttagga ccgttatagt tacggccgcc gtttactggg gcttcgatcc
     1681 gatgctctca catcttcaat taaccttcca gcaccgggca ggcgtcacac cctatacgtc
     1741 cactttcgtg ttagcagagt gctgtgtttt taataaacag tcgcagccac ctattctctg
     1801 cgaccctcca gggcttacgg agcaagtcct taaccttaga gggcatacct tctcccgaag
     1861 ttacggtatc aatttgccga gttccttctc ctgagttctc tcaagcgcct tagaattctc
     1921 atcctgccca cctgtgtcgg tttgcggtac ggttcaattc aaactgaagc ttagtggctt
     1981 ttcctggaag cgtggtatcg gttacttcat gtccgtagac actcgtcatc acttctcggt
     2041 gttaagaaga cccggatttg cctaagtctt ccacctaccg gcttaaacaa gctattccaa
     2101 cagcttgcca acctaacctt ctccgtcccc acatcgcatt tgaatcaagt acaggaatat
     2161 taacctgttt cccatcgact acgcatttct gcctcgcctt aggggccgac tcaccctacg
     2221 ccgatgaacg ttgcgtagga aaccttgggc tttcggcgag cgggcttttc acccgcttta
     2281 tcgctactca tgtcaacatt cgcacttctg atacctccag cacactttac aatgcacctt
     2341 catcggccta cagaacgctc ccctaccatg ccagtaaact ggcatccgca gcttcggtta
     2401 tagatttgag ccccgttaca tcttccgcgc aggacgactc gaccagtgag ctattacgct
     2461 ttctttaaat gatggctgct tctaagccaa catcctggct gtctgggcct tcccacttcg
     2521 tttaccactt aatctatcat tggggacctt agctggcggt ctgggttgtt tccctcttga
     2581 caacggacgt tagcacccgc tgtctgtctc ccgaggaacc acttgatggt attctgagtt
     2641 tgccatgggt tggtaagttg caataacccc ctagccataa cagtgcttta cccccatcag
     2701 tgtcttgctc gaggcactac ctaaatagtt ttcggggaga accagctatc tccgagtttg
     2761 tttagccttt cacccctatc cacagctcat ccccgcattt tgcaacatgc gtgggttcgg
     2821 tcctccagta cctgttacgg caccttcaac ctggccatgg atagatcact cggtttcggg
     2881 tctacaccca gcaactcatc gccctattaa gactcggttt ccctacgcct cccctattcg
     2941 gttaagctcg ctactgaatg taagtcgttg acccattata caaaaggtac gcagtcacac
     3001 ctctagggtg ctcccactgt ttgtatgcat caggtttcag gttctgtttc actcccctcc
     3061 cggggttctt ttcgcctttc cctcacggta ctggttcact atcggtcgat gatgagtatt
     3121 tagccttgga ggatggtccc cccatattca gacaggattt cacgtgtccc gccctacttt
     3181 tcgtacgctt agtaccgctg ttgagatttc gaatacggga ctgtcaccca ctatggtcaa
     3241 gcttcccagc ttgttcttct atctcgacag ttattacgta caggctcctc cgcgttcgct
     3301 cgccactact tgcggaatct cggttgattt cttttcctcc gggtacttag atggttcagt
     3361 tctccgggtt cgcttctcta agtctatgta ttcaacttag gatactgcac agaatgcagt
     3421 gggtttcccc attcggacat cgcgggatca ttgctttatt gccagctccc ccgcgctttt
     3481 cgcaggctta cacgtccttc gtcgcctatc atcgccaagg catccacctg atgcacttat
     3541 tcacttgact ctatcatttc aagaacttct ttgactttgc ctaacattcc gttgactaga
     3601 acatcagact tgaatttcct actttgataa agcttactgc tttgttgtgt cttaatcctg
     3661 ccttttgtgt ttcaggatta agtcgataca atcatcaccc aaatactgtg tttgttttct
     3721 tttctctcgc gagagatttt tatcctttgc aaagaataaa aaatcaaaac aaacgctttg
     3781 tctttgtttg ttgatttcgg ctttccaatt tgttaaagat cgatgcgttc gatattgcta
     3841 tctactgtgc aaatcaaaac gagctgatta ttatatcagc attttgttct tggtcaagtg
     3901 tgacgtcgcc ctgaatggat tctgttccat tcttccgttt tgatttgtac agtattggtg
     3961 gaggcaaacg ggatcgaacc gatgaccccc tgcttgcaaa gcaggtgctc taccaactga
     4021 gctatgcccc cgttcttggt gggtctggga ggacttgaac ctccgacccc acgcttatca
     4081 agcgtgtgct ctaaccagct gagctacaaa cccggattct cttcttaagc gaatcttgcc
     4141 ttcactcaag cttcttccgc atctttttca gtttaccgat aagtgtgaat gcctaaagcc
     4201 tcttctttct ctagaaagga ggtgatccag ccgcaggttc ccctacggct accttgttac
     4261 gacttcaccc cagtcatgaa gcataccgtg gtaagcggac cccttgcggt taccctacct
     4321 acttctggta tcccccactc ccatggtgtg acgggcggtg tgtacaagac ccgggaacgt
     4381 attcaccgca gtatgctgac ctgcgattac tagcgattcc gacttcatgc actcgagttg
     4441 cagagtgcaa tccggactac gatcggtttt gtgagattgg ctccgcctcg cggcttggct
     4501 accctctgta ccgaccattg tatgacgtgt gaagccctgg tcataagggc catgaggact
     4561 tgacgtcatc cccaccttcc tccggcttgt caccggcagt ctcattagag tgcccaactg
     4621 aatgatggca actaatgaca agggttgcgc tcgttgcggg acttaaccca acatctcacg
     4681 acacgagctg acgacagcca tgcagcacct gtgttacggc tcccgaaggc actcctccgt
     4741 ctctggagga ttccgtacat gtcaagacca ggtaaggttc ttcgcgttgc atcgaattaa
     4801 tccacatcat ccaccgcttg tgcgggtccc cgtcaattcc tttgagtttt aatcttgcga
     4861 ccgtactccc caggcggtca atttcacgcg ttagctacgc tactaagcaa tcaagttgcc
     4921 caacagctaa ttgacatcgt ttagggcgtg gactaccagg gtatctaatc ctgtttgcta
     4981 cccacgcttt cgggcatgaa cgtcagtgtt gtcccaggag gctgccttcg ccatcggtat
     5041 tcctccacat ctctacgcat ttcactgcta cacgtggaat tctacctccc tctgacacac
     5101 tcgagtcacc cagttcagaa cgcagttccc gggttgagcc cggggatttc acatcctgct
     5161 taagtaaccg tctgcgcccg ctttacgccc agtaattccg attaacgctc gcaccctacg
     5221 tattaccgcg gctgctggca cgtagttagc cggtgcttat tcttcaggta ccgtcatcag
     5281 ccgctggtat tagcaacagc cttttcttcc ctgacaaaag tcctttacaa cccgaaggcc
     5341 ttcttcagac acgcggcatg gctggatcag gcttgcgccc attgtccaaa attccccact
     5401 gctgcctccc gtaggagtct gggccgtgtc tcagtcccag tgtggcggat catcctctca
     5461 gacccgctac tgatcgtcgc cttggtaggc ctttacccca ccaactagct aatcagatat
     5521 cggccgctcg aatagcgcaa ggcccaaagg tcccctgctt tctctctcaa gacgtatgcg
     5581 gtattagctg atctttcgat cagttatccc ccactactcg gtacgttccg atatgttact
     5641 cacccgttcg ccactcgcca cccgagaagc aagcttctct gtgctgccgt ccgacttgca
     5701 tgtgtaaagc atgccgccag cgttcaatct gagccaggat caaactctta tgttcaatct
     5761 ctaacttttt aacttctggt ctgcttcaaa gaaaccaaca ggacaatgtt caaaacatta
     5821 tcttgtctgt ctttcaaaca gtgtgaggct caaggcactc acacttatcg gtaatctgtt
     5881 ttgttaaaga gcgttgcgaa ttataaagta tctcttccgc ctgtcaagat atctctcgat
     5941 atccccaaca ttctgtgcta tacttttcag ttcgtccgcc gcttctgcag ca
//
LOCUS       DAXISH010000092         5532 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.092, whole genome shotgun sequence.
ACCESSION   DAXISH010000092 DAXISH010000000
VERSION     DAXISH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5532
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.092"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..1044
                     /gene="aldA"
                     /locus_tag="ACFOV4_001960"
     CDS             <1..1044
                     /gene="aldA"
                     /locus_tag="ACFOV4_001960"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HFC7619903.1"
                     /translation="LLFKRPLGVIAGILPWNFPFFLIARKMGPALVTGNTIVVKPSSV
                     TPINCHIFAEIVDAVGLPAGVFNVVNGPGAEIGNALSAHPQVDMVSLTGSVEAGRQVM
                     EAASANITKVSLELGGKAPAIVLKDADLDLAVKSILASRVGNTGQICNCAERVYVHSS
                     LKDAFIEKMTAAMKGVRYGNPAEAEAGALEMGPLIEERAVKAVAEKVERAVKQGAKLV
                     CGGKRAEGRGYFFEPTLLTDTDNSMDIMKEETFGPVLPVSAFDTLDQVIALANDCEFG
                     LTSSVYTTNLNEAFYVTRRLQFGETYINRENFEAMQGFHAGWKKSGIGGADGKHGLEE
                     YLQTQVVYLETDI"
     gene            2080..2421
                     /locus_tag="ACFOV4_001961"
     CDS             2080..2421
                     /locus_tag="ACFOV4_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFC7619904.1"
                     /translation="MRTTPTFPTKTFKPAAMALAVATTLSACLGGGGTSAPDFNAGGT
                     GIGSNSRATTAKSAAVSYAGIKNEMCKDRSMLCAGRDDVAVTDRDAKINAPPRICIPE
                     TLQTQMTHTRI"
     gene            2418..5279
                     /locus_tag="ACFOV4_001962"
     CDS             2418..5279
                     /locus_tag="ACFOV4_001962"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HFC7619905.1"
                     /translation="MINLKPAIEAGYTGRGVEVGIVDTGESVGSISFPELYGRKEHGY
                     NENYKNYTAYMRKEAPEDGDGKDIEASFDDEAVIETEAKPTDIRHVKEIGHIDVVSHI
                     IGGRSVDGRPAGGIAPDATLHIMNTHDGTKNEIMSAAIRNAWVKLGERGVRIVNNSFG
                     TTSRAGTADHFQIANSEEQYRQALLAYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNML
                     FIFSASNDAQAQPNTLTLLPFYEKDAQKGIITVAGVDRSGEKFNGSNHCGITAMWCLS
                     APYEASVRFTRTNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIG
                     AVGVDSKFGWGLLDAGKAMNGPASFPFGDFTADTKGTSDIAYSFRNDISGTGGLIKKG
                     GSQLQLHGNNTYTGKTIIEGGSLVLYGNNKSDMRVETKGALIYNGAASGGSLNSDGIV
                     YLADTDRSGANETVHIKGDLQLGGEGTLYTRLGKLLKVDGTAMTGGKLYMSARGKGAG
                     YLNRTGQRVPFLSAAKIGRDYSFFTNIETDGGLLASLDSVEKTAGSEGDTLSYYVRRG
                     NAARTASAAAHSAPAGLKHAVEQGGSNLENLMVELDASESSATPETVETAAADRTDMP
                     GIRPYGATFRAAAAVQHANAADGVRIFNSLAATVYADSTAAHADMQGRRLKAVSDGLD
                     HNATGLRVIAQTQQDGGTWEQGGVEGKMRGSTQTVGIAAKTGENTTAAATLGMGHSTW
                     SENSANAKTDSISLFAGIRHDAGDIGYLKGLFSYGRYKNSISRSTGADEHAEGSVNGT
                     LMQLGALGGVNVPFSATGDLTVEGGLRYDLLKQDAFAEKGSALGWSGNSLTEGTLVGL
                     AGLKLSQPLSDKAVLFATAGVERDLNGRDYTVTGGFTGATAATGKTGARNMPHTRLVA
                     GLGADVEFGNGWNGLARYSYAGSKQYGNHSGRVGVGYRF"
BASE COUNT         1491 a         1504 c         1435 g         1102 t
ORIGIN      
        1 ttattgttca aacgtccgct gggcgtaatc gccggcattt tgccgtggaa cttccccttc
       61 ttcctgattg cccgcaaaat gggccccgct ttggtaacgg gcaacaccat cgtcgtcaaa
      121 cccagcagcg taaccccgat caactgccac atcttcgccg aaatcgtcga tgcggtcgga
      181 ctgccagcag gcgtgttcaa cgttgtgaac ggtccgggtg cggaaatcgg caatgccttg
      241 tccgcccatc cgcaagtcga tatggtcagc ctgaccggct ccgtcgaagc gggccgccaa
      301 gtgatggaag ccgcttccgc caacatcacc aaagtttcgt tggaactcgg cggcaaagcc
      361 cccgccatcg ttttgaaaga cgcggatttg gatttggcgg tgaaatccat cttggcttcg
      421 cgtgtcggca acaccggtca aatctgcaac tgcgccgagc gcgtttatgt ccacagcagt
      481 ctgaaagacg cattcattga aaaaatgact gccgccatga aaggcgtgcg ctacggcaac
      541 cctgccgaag ccgaagcagg cgcgctggaa atgggcccgc tgattgaaga gcgcgccgtc
      601 aaagccgttg ccgaaaaagt ggaacgggca gtcaaacaag gtgcgaaact ggtctgcggc
      661 ggcaaacgcg ccgaaggacg cggttatttc ttcgagccga ccctgctgac cgacaccgac
      721 aacagtatgg acattatgaa agaagaaacc ttcggccccg ttctgcccgt ttccgctttc
      781 gacacgcttg accaagtcat cgcactggct aacgattgcg agtttggtct gaccagttct
      841 gtttatacga ctaatttaaa cgaagccttc tacgttaccc gccgcctgca attcggcgaa
      901 acctacatca accgcgaaaa ctttgaagcc atgcaaggct tccacgcggg ctggaaaaaa
      961 tccggcatcg gcggcgcgga cggcaaacac ggtttggaag aatatctgca aacccaagtc
     1021 gtttatctgg aaaccgacat ttaatgccgc tttaaaaccc cgatagaaaa tgccgtctga
     1081 acccgttttc aggttcagac ggcattttta cagtttcacc ggcaatcagt catgaccgac
     1141 atcgatgttt ttgtctttgt atagtggatt aacaaaaatc aggacaaggc gacgaagccg
     1201 cagacagtac agatagtacg gaaccgattc actcggtgct tcagcacctt agagaatcgt
     1261 tctctttgag ctaaggcgag gcaacgccgt actggttttt gttaatccgc tatattccgc
     1321 catctctaag atttacagcg atacacgggt gatttaagga atgcccgaac cgtcattccc
     1381 gccactttcc gtcattccca cgaaagtggg aatctagaaa tgaaaagcaa caggcattta
     1441 tcggaaataa ctgaaaccga acagactaga ttcccgcctg cgcgggaatg acgattcata
     1501 agtttcccga aattccaaca taaccgaaac ctgacagtaa ccgtagcaac tgaaccgtca
     1561 ttcccacttt cgtgggaatc tagaaatgaa aagcaacagg catttatcgg aaataactga
     1621 aaccgaacag acctagattc ccgcctgcgc gggaatgacg gctgcagatg cccgacggtc
     1681 tttatagcgg attaacaaaa atcaggacaa ggcgacgaag ccgcagacag tacggaaccg
     1741 attcacttgt taaagaatcg ttctctttga gctaaggcga ggcaacgccg tactggtttt
     1801 tgttcatcca ctataactag ggaaattcaa attaagttag aattatccct ataagaaaaa
     1861 gccgtctaag ccggtataaa caaaataaac tcattgagct atttgtcgaa agttcaaatt
     1921 tccattttaa aacaattagt aaaatcgagt ttatcctagt tgtccaagac aacccctata
     1981 ataatataat tcaaaatata aaaatgggtt acatctaaac attacggaat ttttattccc
     2041 tcgcctgaat tctattgtca gattcaagga gacctcatca tgcgaacgac cccaaccttc
     2101 cctacaaaaa ctttcaaacc ggctgccatg gcgttagctg ttgcaacaac actttctgcc
     2161 tgcttaggcg gcggcggcac ttctgcgccc gacttcaatg caggcggcac cggtatcggc
     2221 agcaacagca gggcaacaac agcgaaatca gcagcagtat cttacgccgg tatcaagaac
     2281 gaaatgtgca aagacagaag catgctctgt gccggtcggg atgacgttgc ggttacagac
     2341 agggatgcca aaatcaatgc ccccccccga atctgcatac cggagacttt acaaacccaa
     2401 atgacgcata caagaatttg atcaacctca aacctgcaat tgaagcaggc tatacaggac
     2461 gcggggtaga ggtaggtatc gtcgacacag gcgaatccgt cggcagcata tcctttcccg
     2521 aactgtatgg cagaaaagaa cacggctata acgaaaatta caaaaactat acggcgtata
     2581 tgcggaagga agcgcctgaa gacggagacg gtaaagacat tgaagcttct ttcgacgatg
     2641 aggccgttat agagactgaa gcaaagccga cggatatccg ccacgtaaaa gaaatcggac
     2701 acatcgatgt ggtctcccat attattggcg ggcgttccgt ggacggcaga cctgcaggcg
     2761 gtattgcgcc cgatgcgacg ctacacataa tgaatacgca tgatggaacc aagaacgaaa
     2821 taatgtctgc agccatccgc aatgcatggg tcaagctggg cgaacgtggc gtgcgcatcg
     2881 tcaataacag ttttggaaca acatcgaggg caggcactgc cgaccatttc caaatagcca
     2941 attcggagga gcagtaccgc caagcgttgc tcgcctattc cggcggtgat aaaacagacg
     3001 agggtatccg cctgatgcaa cagagcgatt acggcaactt gtcctaccac atccgtaata
     3061 aaaacatgct tttcattttt tcggcaagca atgacgcaca agctcagccc aacacactga
     3121 ccctattgcc attttatgaa aaagatgctc aaaaaggcat tatcacagtc gcaggcgtag
     3181 accgcagtgg agaaaagttc aatggctcca accattgcgg aattactgcc atgtggtgcc
     3241 tatcggcacc ctatgaagca agcgtccgtt tcacccgtac aaacccgatt caaattgccg
     3301 gaacatcctt ttccgcaccc atcgtaaccg gcacggcggc tctgctgctg cagaaatacc
     3361 cgtggatgag caacgacaac ctgcgtacca cgctgctgac aacggctcag gacatcggtg
     3421 cagtcggcgt ggacagcaag ttcggctggg gactgctgga tgcgggtaag gccatgaacg
     3481 gacccgcgtc ctttccgttc ggcgacttta ccgccgatac gaaaggtaca tccgatattg
     3541 cctactcctt ccgtaacgac atttcaggca cgggcggcct gatcaaaaaa ggcggcagcc
     3601 aactgcaact gcacggcaac aacacctata cgggcaaaac cattatcgaa ggcggttcgc
     3661 tggtgttgta cggcaacaac aaatcggata tgcgcgtcga aaccaaaggt gcgctgattt
     3721 ataacggggc ggcatccggc ggtagcctga acagcgacgg cattgtctat ctggcagata
     3781 ccgaccgatc cggcgcaaac gaaaccgtgc acatcaaagg cgatctgcag ctgggcggcg
     3841 aaggtacgct gtacacacgt ttgggcaaac tgctgaaagt ggacggtacg gcgatgaccg
     3901 gcggcaagct gtacatgtcg gcacgcggca aaggggcagg ctatctcaac cgtaccggac
     3961 aacgtgttcc cttcctgagt gccgccaaaa tcgggcggga ttattctttc ttcacaaaca
     4021 tcgaaaccga cggtggtctg ctggcttccc tcgacagcgt cgaaaaaaca gcgggcagtg
     4081 aaggcgacac gctgtcctat tatgtccgtc gcggcaatgc ggcacggact gcttcggcag
     4141 cggcacattc cgcgcccgcc ggtctgaaac acgccgtaga acagggcggc agcaatctgg
     4201 aaaacctgat ggtcgaactg gatgcctccg aatcatccgc aacacccgag acggttgaaa
     4261 ctgcggccgc cgaccgcaca gatatgccgg gcatccgccc ctacggcgca actttccgcg
     4321 cagcggcagc cgtacagcat gcgaatgccg ccgacggtgt acgcatcttc aacagtctcg
     4381 ccgctaccgt ctatgccgac agtaccgccg cccatgccga tatgcaggga cgccggctga
     4441 aagccgtatc ggacgggttg gaccacaacg ctacgggtct gcgcgtcatc gcgcaaaccc
     4501 aacaggacgg tggaacgtgg gaacagggcg gtgttgaagg caaaatgcgc ggcagtaccc
     4561 aaaccgtcgg cattgccgcg aaaaccggcg aaaatacgac agcagccgcc acactgggca
     4621 tgggacacag cacatggagc gaaaacagtg caaatgcaaa aaccgacagc attagtctgt
     4681 ttgcaggcat acggcacgat gcgggcgata tcggctatct caaaggcctg ttctcctacg
     4741 gacgctacaa aaacagcatc agccgcagca ccggtgcgga cgaacatgcg gaaggcagcg
     4801 tcaacggcac gctgatgcag ctgggcgcac tgggcggtgt caacgttccg ttttccgcaa
     4861 cgggagattt gacggtcgaa ggcggtctgc gctacgacct gctcaaacag gatgcattcg
     4921 ccgaaaaagg cagtgctttg ggctggagcg gcaacagcct cactgaaggc acactggtcg
     4981 gactcgcggg tctgaagctg tcgcaaccct tgagcgataa agccgtcctg tttgcaacgg
     5041 cgggcgtgga acgcgacctg aacggacgcg actacacggt aacgggcggc tttaccggcg
     5101 cgactgcagc aaccggcaag acgggggcac gcaatatgcc gcacacccgc ctggttgccg
     5161 gtctgggcgc ggatgtcgaa ttcggcaacg gctggaacgg cttggcacgt tacagctacg
     5221 ccggttccaa acagtacggc aaccacagcg gacgagtcgg cgtaggctac cggttctgac
     5281 ggacaggaag cagacagccg caaagatcac ggtctttgcg gctgtttctt atgaaaagaa
     5341 aaccctattc caattgcctg cttctattgt ttcaagactt cttccaaaga ttcggcatta
     5401 atcagatgta tagcggatta acaaaaatca ggacaaggcg gcgaagccgc agacagtaca
     5461 aatagtacgg aaccgattca ctcggtgctt gagcacctta gagaatcgtt tctttgagct
     5521 aagtcgaggc aa
//
LOCUS       DAXISH010000093         4814 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.093, whole genome shotgun sequence.
ACCESSION   DAXISH010000093 DAXISH010000000
VERSION     DAXISH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4814
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.093"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(456..800)
                     /locus_tag="ACFOV4_001963"
     CDS             complement(456..800)
                     /locus_tag="ACFOV4_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619906.1"
                     /translation="MIIEHNGNIHKIARMTGNKNNFLEIILSDIHENIKIKPLTIKVK
                     GENVINILPEEVSFYVKQGVDLIYEKYKRKFFISEISFCQSDSRPSSIYAFLTFHLLE
                     DIIKNESPSNYT"
     gene            complement(838..1161)
                     /locus_tag="ACFOV4_001964"
     CDS             complement(838..1161)
                     /locus_tag="ACFOV4_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619907.1"
                     /translation="MFLDDVNVFLDDLNTNPITDEWYMSNFADKHIKILESYETFDIL
                     KQFVDYMIEEYDEKSEYEIMEILRQLKYQADTNEKFYTNTQKQKIVELYKQEISQDIL
                     NEIFR"
     gene            complement(1164..1448)
                     /locus_tag="ACFOV4_001965"
     CDS             complement(1164..1448)
                     /locus_tag="ACFOV4_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619908.1"
                     /translation="MAGGNKSLKIGTQSVEKSTGRTIPNNLKEQLAMEEVKANPQGKT
                     PARIPPMSDTKNGWLAKDGWVKRVQNVNKIEIHYIENSRTGEKTDFKFKD"
     gene            complement(1431..1757)
                     /locus_tag="ACFOV4_001966"
                     /pseudo
     CDS             complement(1431..1757)
                     /locus_tag="ACFOV4_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257312.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI.; incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
     gene            complement(1863..2234)
                     /locus_tag="ACFOV4_001967"
     CDS             complement(1863..2234)
                     /locus_tag="ACFOV4_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042546 - cell wall biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="HFC7619909.1"
                     /translation="MIKQNSFVPYPEAMLPKGFKYPQSYLKLAQSTHAINYDEQYSFP
                     WWFENAESNISEVIDIYFEITGIPNLLPFARNQEWAACFDISDKSGNPKIIVVNLDNT
                     KYYETFENFDTWLKEAENDGW"
     gene            complement(2231..2586)
                     /locus_tag="ACFOV4_001968"
                     /pseudo
     CDS             complement(2231..2586)
                     /locus_tag="ACFOV4_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012504007.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2614..2820)
                     /locus_tag="ACFOV4_001969"
     CDS             complement(2614..2820)
                     /locus_tag="ACFOV4_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619910.1"
                     /translation="MNILSINNQNSTISLTQDEVFVLRAILNEIYAGVCVDSREFENV
                     SGVRKHEVDNLQQQFAGIYKKMTT"
     gene            complement(2830..3675)
                     /gene="mafB"
                     /locus_tag="ACFOV4_001970"
                     /pseudo
     CDS             complement(2830..3675)
                     /gene="mafB"
                     /locus_tag="ACFOV4_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246532.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 3"
     gene            complement(3772..3984)
                     /locus_tag="ACFOV4_001971"
     CDS             complement(3772..3984)
                     /locus_tag="ACFOV4_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619911.1"
                     /translation="MKLINFEESSVKISLDKDELYIIQAIVGEIYSGVCVDCRDFEII
                     HGVEKIKFFLWIKNLKKYMILGINVS"
     gene            complement(4061..4420)
                     /locus_tag="ACFOV4_001972"
     CDS             complement(4061..4420)
                     /locus_tag="ACFOV4_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 8 family protein"
                     /protein_id="HFC7619912.1"
                     /translation="MRLKLKNYDCSDFDLEDFPQDKLENFCILLTLSIGFDESNGADY
                     FYVYIYSTEWLLSNIHRPMSLKNSIVTNRFNIEHILKLINDILEICNSTSEDKSISNL
                     AKYFDWEFDDYNLNIQD"
     gene            complement(4425..>4814)
                     /locus_tag="ACFOV4_001973"
     CDS             complement(4425..>4814)
                     /locus_tag="ACFOV4_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619913.1"
                     /translation="PPKSITSGGKANAATYPQLVNQLTGQNLKNIAAQDPRLSLALHK
                     SEKNFPIGTATYEEADRLGKIWVGEGARQTSGGGWLSIDGTRQYRPPTEKNSQFATTG
                     IQANFETYTIDSNGKRNKIKNGHLNIR"
BASE COUNT         1340 a          935 c          762 g         1777 t
ORIGIN      
        1 attaatacct tgtaaagttt gctgcgcaga gatgtaggtc ggatatttgt atccgacaaa
       61 aatatttgac gcatctatcg tttccgaaat gccgctgttg gaaaatgtcg gattcgagaa
      121 tccgacctac ggctatttcg tttaagtcat aaatagccat tcatgttcct tctgaatttg
      181 cttttgctat ccttagaacc aatcatataa acattatcat cattaattaa tgttctaagt
      241 ttatgaagcg gtcaaatctg tcaaactacc agagatgaag catatcctcc tggaagtaat
      301 tctgttcgtg ctgtttccat atcttctttg ccatcatcag ttacttctct gtctaaataa
      361 aatcttacga taagtttttg tctaatttca tcaaattctg ccgtaattaa tcttatattg
      421 atatgaatac acggttcata cctgctatta gccagtcagg tgtagttgga tggggattca
      481 tttttaataa tatcttcaag caagtgaaat gtaagaaaag cgtagatact tgaaggccgg
      541 ctatctgatt ggcaaaaaga aatttcggag ataaagaatt tccgtttata tttttcataa
      601 attaaatcaa caccttgttt tacataaaaa ctaacttcct caggaaggat atttataaca
      661 ttctctcctt ttacttttat agttaatggt ttgattttta tgttttcatg aatatctgat
      721 aggattattt ctaaaaaatt atttttattt ccagtcattc tggctatttt atgtatattt
      781 ccattgtgtt cgattatcat tttatttttt ccaaggattt ccttctatat tgatagttta
      841 tctaaagatt tcatttaaaa tatcctgact aatttcttgt ttatataatt ctacaatttt
      901 ctgtttctgt gtatttgtat aaaatttttc gttggtatct gcttgatatt ttaattgtct
      961 caatatttcc atgatttcat attctgattt ttcatcatat tcttcaatca tgtaatcaac
     1021 aaattgtttt agaatatcaa aggtttcgta actttccaaa attttaatat gtttatcggc
     1081 aaaattggac atataccatt cgtcagtgat tggattagta tttaaatcat ctaaaaaaac
     1141 atttacatca tctaaaaaca tgactaatcc ttaaacttaa aatctgtttt ctcaccggtt
     1201 cttgagtttt caatgtaatg tatttcaatt ttgtttacgt tttgaacacg cttaacccaa
     1261 ccgtcttttg ctaaccaacc atttttagta tcggacatag gaggtattct cgcaggagtt
     1321 ttgccctgtg ggtttgcctt aacttcttcc attgctaatt gttcctttaa attattaggt
     1381 attgtacgac cggttgattt ttcaacagat tgtgtcccta tttttaatga tttgtttccc
     1441 ccagccattt ccccgtctac agtctgcata gggcgggcag caggtttttt atagccggta
     1501 tttttaaccc aatcccattt agtcgggtta agttctactt ttttaccgcg ccaaaccgta
     1561 cctgcggcct ctgctacgga aagggcagtt tgggctgttg cagttatatt cggatgggca
     1621 tcagcccatt gtctggcgga attaatgccg ttttttaccg caaaagcact gtcctgtaat
     1681 aggctcgcgg cagcaagttg tgcttccgga cttaaatttc ctaattcatt aatatcttgt
     1741 aaagtttgct gcgcagagat gtaggtcgga tatttgtatc cgacaaaaat atttgacgcg
     1801 tctatcgttt ccgaaatgcc gctgttggaa aatgtcggat tcgagaatcc gacctacggc
     1861 tgctaccaac catcattttc agcttctttt agccaagtat caaaattttc aaaagtctcg
     1921 taatattttg tattatctaa attaactact ataattttag gattacctga tttatctgaa
     1981 atatcaaaac aggcagccca ctcttggttt ctagcaaaag gtaataggtt tggaatgcca
     2041 gttatttcaa aataaatgtc aattacttct gatatattgc tttctgcatt ttcaaaccac
     2101 caaggaaaag aatattgttc atcgtagtta atggcatgag tggattgagc taattttaaa
     2161 taactttgcg gatatttaaa tcctttagga agcattgctt caggatacgg aacaaaacta
     2221 ttttgtttta tcatttccta agtaccttta catcataaat acttccgtta ggaaatcttt
     2281 tgctccaccc ttctggaact cctttttgtg tttcttgctt tctaattcgt agctggatag
     2341 cttctcccca agtttgaggc tcaataccat catgcttaaa cctgattctc tcttttgatg
     2401 ataatcggtc attaaaatta tgaacattcg cttccacttt tacccctgct tcatgtgctg
     2461 ccataatacg cgtgttatcc atactagtag gtgctccatc aggcatatta acaacatcaa
     2521 ccctgtcgcc aacccatgat ttttttcgtt cattgcagct acaagagaat catagttgta
     2581 atttgcacta ggctctgaca aaaatttggg ttgttaagtt gtcatttttt tataaattcc
     2641 agcaaactgt tgttgtaaat tatctacttc atgttttcta acaccagata cattttcaaa
     2701 ttctcttgaa tctacacata cgcccgcata tatctcattc aagatagctc gtaaaacaaa
     2761 aacttcatct tgagttagtg aaatagttga gttttgatta tttatggata gtatattcat
     2821 ggctttttcc tataaatcat cataatattt tttacctgat gttggtctaa atgctgtacc
     2881 tccatcgtca gaatttttat ctcggataac tattgtccct gttttatcat cccaatacgc
     2941 agttctaccg cgaggtaact ctttcatatt tgttggatgg ctaacaatat tttcaatatg
     3001 ccgagcaaaa tctgctggtg aattgatatt taaatccgta aattcttgtt gtcttatgac
     3061 atgcttgtta taagcatgcc cactactaat ttgttctcca attagttgcg cttgtaaaga
     3121 cggttgtgtg gaagcatctg ctttgctgtt ggacgttata gatttaggcg gtctattccc
     3181 ccctgccatc tccccatcta cagtctgcat atggcgggca gcaggttttt tatagccggt
     3241 atttttaacc caatcccatt tggtcgggtt aagttctact tttttaccgc cccaaaccgt
     3301 agttgcggcc tctgctacgg caagggcagt ttgggctgtt gcagttatat tcggatgggc
     3361 atcagcccat tgtttggcag agttgatacc gtcttttacc gcaaaagcac tgtcttgtaa
     3421 tgcggttgca gccgcaagtt gtgcttcggg acttaaattt cctaaatgat taataccttg
     3481 tagagtctgc tgcgcggctg tatctgtgac cgggcttact gcactgtctg taattgcccc
     3541 aatccctact ccttgaaaac ccattaaaaa aggattaacc gcaccttgga cgatgccgcg
     3601 aacatcatcc atacggttag cccaccaatt tttattgggg tcgttttccc atatcagttt
     3661 tcctgcttca tcagcacagt taggattggc attgatgccc acccagtttc aggcagcctg
     3721 aaaaggattt ttaatatacg gcaaaaggtg ggcaacaagt gcccacctta cctagctaac
     3781 atttatccca agtatcatat atttttttaa gttctttatc caaagaaaga actttatttt
     3841 ttcaacacca tgaattatct caaaatctct acaatccacg catacgcctg aataaatttc
     3901 tcctacaatt gcttgaataa tatacaactc atctttatcg agactaattt taactgaact
     3961 ctcttcaaaa ttaattaatt tcatgaataa ttccttttat tttaattcgt catcaaaata
     4021 ccgtttgcct gtttttggtc taaatgctgt cccaccatct ttagtcttgg atatttagat
     4081 tataatcgtc aaattcccag tcaaaatatt ttgccaaatt tgatatagac ttatcttcag
     4141 acgttgaatt acatatttcc aatatatcat ttatcaattt taatatgtgt tcaatattaa
     4201 aacggtttgt aacaattgag ttttttaatg acatcggtct atgtatattt gaaagtaacc
     4261 attcagtgct atatatataa acataaaaat aatcagcacc attactttca tcaaaaccta
     4321 ttgataatgt caaaagtata caaaaatttt ctaacttgtc ttgtgggaaa tcttccaaat
     4381 caaagtcaga acaatcataa ttttttaatt ttaatctcat ataattacct aatatttaaa
     4441 tgtccatttt taattttatt cctttttcca tttgaatcaa tagtataagt ttcaaaattt
     4501 gcttgaatac ctgtagttgc aaattgtgaa tttttttctg ttggtggccg atattgtcga
     4561 gtgccatcta tacttaacca tccgcctcca ctagtttgtc ttgcaccctc accaacccaa
     4621 attttaccta gcctatctgc ctcttcataa gttgcagttc ctattggaaa atttttttca
     4681 ctcttatgaa gagctagact caatcttgga tcttgagccg caatgttttt taagttttgc
     4741 ccagttaatt gattaactaa ttgaggataa gttgcagcat tggcttttcc tccagacgtt
     4801 atagatttag gcgg
//
LOCUS       DAXISH010000094         4745 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.094, whole genome shotgun sequence.
ACCESSION   DAXISH010000094 DAXISH010000000
VERSION     DAXISH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4745
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.094"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            1..643
                     /locus_tag="ACFOV4_001974"
                     /pseudo
     CDS             1..643
                     /locus_tag="ACFOV4_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153708080.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(779..2182)
                     /locus_tag="ACFOV4_001975"
     CDS             complement(779..2182)
                     /locus_tag="ACFOV4_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HFC7619914.1"
                     /translation="MTLLNLMIMQDYGISVCLTLTPYLQHELFSAMKSYFSKYILPVS
                     LFTLPLSLSPSVSAFTLPEAWRAAQQHSADFQASHYQRDAVRARQQQAKAAFLPHVSA
                     NASYQRQPPSISSTRETQGWSVQVGQTLFDAAKFAQYRQSRFDTQAAEQRFDAAREEL
                     LLKVAESYFNVLLSRDTVAAHAAEKEAYAQQVRQAQALFNKGAATALDIHEAKAGYDN
                     ALAQEIAVLAEKQTYENQLNDYTDLDSKQIEAIDTANLLARYLPKLERYSLDEWQRIA
                     LSNNHEYRMQQLALQSSGQALRAAQNSRYPTVSAHVGYQNNLYTSSAQNNDYHYRGKG
                     MSVGVQLNLPLYTGGELSGKIHEAEAQYGAAEAQLTATERHIKLAVRQAYTESGAARY
                     QIMAQERVLESSRLKLKSTETGQQYGIRNRLEVIRARQEVAQAEQKLAQARYKFMLAY
                     LRLVKESGLGLETVFAE"
     gene            complement(2251..3678)
                     /locus_tag="ACFOV4_001976"
     CDS             complement(2251..3678)
                     /locus_tag="ACFOV4_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0030253 - protein secretion by the type I
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion periplasmic adaptor
                     subunit"
                     /protein_id="HFC7619915.1"
                     /translation="MFFSALKSFLSRYITVWRNVWAVRDQLEPPKRTAEEQAFLPAHL
                     ELTDTPVSAAPKWAARFIMAFALLALLWSWFGKIDIVAAASGKTVSGGRSKTIQPLET
                     AVVKAVHVRDGQHVKQGETLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALES
                     RTVPHIDMAQARSLGLSDADVQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKA
                     QEQKLVSVGAIEQQKTADYRRLRADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQ
                     AAIAQAEQSRVLNTQNLKRDTLDALRQANEQIDQYRGQTDKAKQRQQLMTIQSPADGT
                     VQELATYTVGGVVQAAQKMMVVAPDDDKMDVEVLVLNKDIGFVEQGQDAVVKIESFPY
                     TRYGYLTGKVKSVSHDAVSHEQLGLVYTAVVSLDKHTLNIDGKAVNLTAGMNVTAEIK
                     TGKRRVLDYLLSPLQTKLDESFRER"
     gene            3914..4267
                     /locus_tag="ACFOV4_001977"
     CDS             3914..4267
                     /locus_tag="ACFOV4_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619916.1"
                     /translation="MFTTNDLRHFLEGLAILFSIGYWGTMLLLLWFLVRFAYKKPKRN
                     PGKILSGSLTAAAILMLFVWIIPKQFGPIKEEIQAQEEWDRKYKEAEAVFNEQCKTAG
                     ERFTRRRTMWKGLCC"
     gene            4204..>4745
                     /locus_tag="ACFOV4_001978"
     CDS             4204..>4745
                     /locus_tag="ACFOV4_001978"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619917.1"
                     /translation="MQNGGGKIYQTADNVEGIMLLKVVPERTVSADAKTRDPMWDNAA
                     LQTSEGVNFIARFLGFFSDGEYRYVDVLQPNHSDIIRYSGKDFPINQILNHIHPARYA
                     VTFENNVDSKLRRHWVAGATIRIIDRQTDEVIAKKTIYVFEKGLDGTGGARMPWKFAI
                     LCNKERLTSSEPLSDFVLSV"
BASE COUNT         1144 a         1240 c         1157 g         1204 t
ORIGIN      
        1 tgaaatcgcc aaacattttg attgtacggc agccaccatt tgctatgcac tcaaacagat
       61 ggggataacg cgcaaaaaaa gaccaccact tacaaagaac aagacccggc caaagtaacg
      121 cattatttga cacagccggc cgaattttcc gactaccaac gtgtttattt ggatgaaaca
      181 ggatttgacc gctacctgtt ccgtccctat gcccgcagcc tgaaagggca aatagtgaaa
      241 gcgcagataa gtggaaaaag ataccaacgc ttatctttgg tgtccgcaca agtcggcaac
      301 cggctgattg ctccgatggt ttatcaaaat acgatgaccg gagtcttttt tgaagcgtgg
      361 tttcagcaat gcctactgcc cgcattgact caaaaatcgg tgattatttt agataatgcg
      421 cgatttcacc gtatgggtgt cttacgggaa atggcggaaa aattgggaca taaggtattg
      481 cctcttgcac cttattcacc tgagctcaac ccgattgaga aagtgtgggc gaatattaag
      541 cggtatctgc gaaccgtttt gtctgattac gcccgatttg acgatgcact actgtcctat
      601 tttgatttta attgaatata catttgaatt aattcgcact taatttaaat gtgtttttaa
      661 ctgtgcttta tttaaaggca atgagaatgt gaaagtatcg gatcaatccc aaagcagcct
      721 gcactttcga aacggggtgc aggctgcttt gggaatttca taaccgtttc agcctgcttt
      781 attccgcaaa taccgtttcc aaccctaacc cgctctcttt caccaagcgc aaataagcca
      841 gcatgaattt ataccgtgct tgagccagtt tctgttctgc ttgggcgact tcctgccgcg
      901 cccgtattac ttccagccgg ttgcggatgc cgtattgttg gccggtttcg gtcgatttca
      961 gtttcaaacg gctgctttcc aaaacccgtt cttgcgccat gatttggtaa cgcgccgcac
     1021 cgctttcggt ataagcttgg cgtacggcga gtttgatgtg ccgctcggtt gcggtcagct
     1081 gtgcttcggc ggccccgtat tgcgcttcgg cttcatggat tttgcccgac aattctccgc
     1141 cggtataaag cggcaaattc aactgtacgc cgacgctcat ccctttgccc cgatagtggt
     1201 agtcattatt ctgcgcagat gaagtgtaga ggttattctg atagccgaca tgggcagaaa
     1261 cggtgggata gcggctgttc tgtgctgccc gaagcgcctg tccgctgctt tgcagggcaa
     1321 gctgctgcat ccggtattca tgattgttgg ataaggcaat gcgctgccat tcatccagac
     1381 tgtaacgttc cagcttgggc agatagcgtg ccaacaggtt ggcggtatct atggcctcga
     1441 tttgtttgct atccaggtcg gtgtagtcgt tcaactggtt ttcataggtt tgtttctcag
     1501 ccaatacggc gatttcttgg gccagggcat tgtcgtaacc ggctttggct tcgtgaatat
     1561 ccagcgcggt ggcagcacct ttattgaata aagcctgcgc ctgccttacc tgctgggcat
     1621 aagcctcttt ttccgccgca tgggcggcaa cggtgtctcg gctgagtaaa acgttgaaat
     1681 aactttcggc aactttcaac agcaattctt cgcgtgccgc atcgaaacgc tgttctgcag
     1741 cctgcgtatc gaacctgctt tggcggtatt gtgcaaattt ggcagcgtca aataaggttt
     1801 gtcccacctg cacgctccat ccctgtgttt cgcgggtgga agaaatcgat ggcggctggc
     1861 gctggtagct ggcattggcg gatacatggg gaaggaatgc ggccttggct tgttgttgcc
     1921 gtgcgcgcac tgcatcacgc tggtaatggg acgcttgaaa atcagccgaa tgttgctgcg
     1981 ccgcccgcca tgcttcaggc agcgtaaaag ccgaaacgga tggggaaagg gatagtggca
     2041 aggtaaaaag tgaaacgggt aggatatatt tggaaaaata ggatttcata gccgaaaata
     2101 gttcatgttg caaatagggc gtcagtgtca ggcaaacgga aataccgtaa tcttgcatta
     2161 tcattagatt gagcaatgtc atccgggcaa tggtttcagg cagtctgcat gtccgaaccg
     2221 gcggataaca aatgcccagt acggatccgc ctatcgctcc ctaaagcttt cgtccaattt
     2281 ggtttgcagc gggcttaaca gataatccag cacccgccgt ttacccgttt taatctccgc
     2341 cgtgacattc atgcccgccg tcagattcac tgctttgccg tcaatattca aggtatgttt
     2401 gtccagcgac accaccgccg tataaaccaa gcccaactgt tcgtggctta ccgcatcatg
     2461 gctgacactt ttcaccttgc ccgtcagata accgtagcgc gtatagggaa aactctcaat
     2521 cttcaccacc gcatcctgtc cctgttccac aaaaccgatg tctttgttca ataccaaaac
     2581 ttccacgtcc attttgtcgt catcgggcgc aaccaccatc attttttggg cagcctgcac
     2641 cacaccgccc accgtatagg tggccaattc ctgcaccgtg ccgtccgcag gcgactgtat
     2701 tgtcatcagc tgctgccgct gctttgcctt atccgtttgg ccgcggtatt ggtcaatctg
     2761 ttcgtttgcc tggcgcagcg catccagcgt atcgcgtttc aggttctgcg tattcagcac
     2821 ccgactctgc tccgcctgtg caatggccgc ctgaatctgc ctcatctgac cgcgcgtact
     2881 ttccaaatcg ttccaattgc tgaccgattt gctctgctgc tccaaaaacg catgttccga
     2941 aataaaattg tcggcccgca aacggcggta gtctgctgtt ttctgctgct cgatcgcccc
     3001 caccgaaacc agcttctgct cctgcgcctt ggccgactgc aattccgcct gatggccgcg
     3061 caaagccgac tgcaattgcg catcctgcgc cgcccatgcc tgatactggt gctgcgccaa
     3121 cacctgcgcc gattgcacat cggcatcgga gagacctaaa gaccgtgctt gcgccatatc
     3181 gatatgcggc acggtacggc tttccaatgc cgccaatacc gcttcataac gcagtttgga
     3241 caattgggca gcctgcaaag cctgctccga ctgcaccaca tcgctgtctg ttcccacagc
     3301 ctccagttcc gccagcgttt ctccctgttt cacatgctgc ccgtcgcgca catgtaccgc
     3361 cttaaccacc gccgtttcca gcggctggat ggttttgctg cgcccgcccg acaccgtttt
     3421 gcccgaagcc gccgccacaa tatcgatttt gccgaaccag gaccacaaca aagccaaaag
     3481 cgcaaacgcc ataataaaac gcgccgccca tttcggagcg gcagagaccg gcgtatcggt
     3541 cagttccaaa tgcgcgggca aaaacgcctg ttcttccgcc gtgcgtttgg gcggttccaa
     3601 ctggtcgcgc accgcccaaa cattgcgcca tacagtaatg tatcgagaaa gaaaggattt
     3661 cagggcggag aaaaacataa cgggtataac cttggcaata tagaaacagg aaacaatata
     3721 aatatgtaaa ggaattttaa cggaaagcgc ggcagctgtt aagggaaagg cgggaatatt
     3781 gacaaaaaat acccaagtcg ttacaaatat tcattatttt actgcgtaac gcaacgctga
     3841 agcgcaggct gcttttgaga tgcggcaagg ttcggcaaaa agcagcctgc acatttaacc
     3901 acaggaacaa cccatgttta ccacaaacga tttacgccat ttcctagaag gtttggccat
     3961 cctattctca atcggctatt ggggcaccat gctgctgttg ctttggtttc tcgtccgctt
     4021 tgcctataaa aagcccaaac ggaaccccgg caaaatcctt tcaggcagcc tgaccgccgc
     4081 cgctatcctg atgctgtttg tttggattat tcccaaacaa ttcggcccga tcaaagaaga
     4141 aatacaggca caagaagagt gggacagaaa atacaaagaa gccgaagccg tgtttaacga
     4201 acaatgcaaa acggcggggg aaagatttac cagacggcgg acaatgtgga agggattatg
     4261 ctgttgaagg tagtacctga gcgtaccgtt tcggcagatg caaaaaccag agacccgatg
     4321 tgggacaatg cggctttaca gaccagcgaa ggcgtaaatt ttattgctcg tttcctagga
     4381 ttttttagcg atggggaata ccgctatgtg gatgtcctgc aacccaacca ttccgatatt
     4441 attcggtatt caggtaaaga ttttccgata aatcaaatac ttaatcatat acaccccgcc
     4501 cgttatgcgg taacgttcga aaacaatgtc gattccaagc tgcgcaggca ctgggtggca
     4561 ggtgcgacca tacggattat cgaccgccaa actgacgaag tgattgccaa gaaaaccatc
     4621 tatgtctttg aaaaaggctt ggacggcacg ggtggggcga gaatgccgtg gaagtttgct
     4681 atcttgtgca ataaagaaag acttacttct tcagagccgt tatcggattt tgttcttagc
     4741 gtttt
//
LOCUS       DAXISH010000095         4739 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.095, whole genome shotgun sequence.
ACCESSION   DAXISH010000095 DAXISH010000000
VERSION     DAXISH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4739
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.095"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(13..222)
                     /locus_tag="ACFOV4_001979"
     CDS             complement(13..222)
                     /locus_tag="ACFOV4_001979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619918.1"
                     /translation="MPSENLSDGIFLPKQPYFLSGLQNLSETTETTLPSFPQKRESRT
                     QHGKNLSEATTIFSSSFPRRRESRT"
     gene            complement(239..1177)
                     /locus_tag="ACFOV4_001980"
     CDS             complement(239..1177)
                     /locus_tag="ACFOV4_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC7619919.1"
                     /translation="MLELNGLCKRFGNKTVADDICLTVGRSKILAVLGRSGCGKSTLL
                     NMIAGIIRPDGGEIRLNGENITRMPPEKRRISLMFQDYALFPHMSALENAAFGLKMQK
                     MPKAEAESLAMAALAEVGLENEAHRKPEKLSGGEKQRLALARALVVRPSLLLLDESFS
                     SLDTHLRDRLRRMTAERIRKGGIPAVLVTHSPEEACTAADEIAVMHEGKILQCGTPET
                     LVQTPAGVQVAHLMGLPNTDDDRHIPQHAVRFDQNGMECRVLSRTCLPESFSLSVLHP
                     EHGILWLNLDMRHAGAVSGKDTVRIHIEEREIVRFR"
     gene            complement(1186..2061)
                     /locus_tag="ACFOV4_001981"
     CDS             complement(1186..2061)
                     /locus_tag="ACFOV4_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFC7619920.1"
                     /translation="MPTVRFTESVSKQDLDALFEWAKASYGAKSCWKTLYLNRLPLGN
                     LSPEWAERVKKDWEAGCSESSDGIFLNADGWTDMGGRLQHLARTWNKAGLLHGWRNEC
                     FDLTDGGGNPLFTLERAAFRPFGLLSRAVHLNGLTESDGRWHFWIGRRSPHKAVDPDK
                     LDNTAAGGVSSGELPSETVCRESSEEAGLDKTLFPFIRPVSRLHSLRPVSRGVHNEIL
                     YVFDAILPETFLPENQDGEVACFEKMDIGGLLDAMLSENMMHDAQLVTLDAFCRYGLI
                     DAAHPLSEWLDGIRL"
     gene            complement(2250..2326)
                     /locus_tag="ACFOV4_001982"
     tRNA            complement(2250..2326)
                     /locus_tag="ACFOV4_001982"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2290..2292),aa:Met,seq:cat)
     regulatory      2476..2575
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            2668..4569
                     /gene="thiC"
                     /locus_tag="ACFOV4_001983"
     CDS             2668..4569
                     /gene="thiC"
                     /locus_tag="ACFOV4_001983"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HFC7619921.1"
                     /translation="MTTPKKTAKTSGNEARELADLSEDIGIRFKYPNSERVYLQGSRD
                     DIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGVYGDPAAHIDLKQGLPHIRTAWLDE
                     RGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPE
                     MEFVAIRERLKLDELSQKPEYAKLLKQHAGQSFGANIPTRPDQITPEFVRREIAAGRA
                     IIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDL
                     STGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFRDTLIEQAEQGVD
                     YFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAY
                     DVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVK
                     ENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHL
                     GLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPE
                     RAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEF
                     VKKGAKIYS"
BASE COUNT         1145 a         1330 c         1256 g         1008 t
ORIGIN      
        1 tttctttaga ttttacgttc tagattcccg cctgcgcggg aatgacgatg aaaagattgt
       61 tgtcgcttcg gataaatttt tgccgtgttg ggttctagat tcccgctttt gcgggaatga
      121 cggcagggtg gtttctgttg tttcggataa attttgcagc cctgataaaa aatatggctg
      181 ctttggtaaa aaaatgccgt ctgaaaggtt ttcagacggc atttgttttt aagaagcatc
      241 agcggaagcg gacgatttcc cgttcttcga tatggatgcg taccgtatcc ttgcccgata
      301 ccgccccggc gtgccgcata tcgaggttca gccataggat gccgtgttcc ggatggagga
      361 cggacaggct gaacgattcg ggcaaacagg tacgggataa tacgcggcac tccatgccgt
      421 tttggtcgaa acgcaccgca tgttgcggaa tatggcggtc atcgtcggta ttgggcagcc
      481 ccatcagatg ggcgacctgc acgccggcag gcgtttgaac caaggtttcg ggcgtaccgc
      541 attgaaggat tttcccctcg tgcatgacgg cgatttcgtc tgccgccgtg caggcctctt
      601 cgggcgaatg cgttaccaaa acggcaggga tgccgccctt gcggatacgt tcggcagtca
      661 tgcggcgcag ccggtcgcgc aaatgcgtgt ccaaactgga aaacgattcg tccaacagca
      721 gcagggaagg gcggacaacc aaagcgcgcg ccagtgccaa ccgttgcttt tcgcctccgg
      781 aaagtttttc aggcttgcgg tgcgcctcgt tttccagtcc gacttcggca agtgccgcca
      841 tggcgaggct ttcggcttcg gctttcggca ttttttgcat tttcaaaccg aatgccgcat
      901 tttccagtgc actcatatgg ggaaacagcg cgtaatcttg aaacatcagc gaaatacggc
      961 gtttttcggg cggcatacgg gtaatgtttt ccccgttcag ccgaatttcg ccgccgtccg
     1021 gacggataat ccccgcaatc atattcagca gggtggattt tccgcagccc gaccgtccca
     1081 aaacggcaag tattttgctg cggccgacag tcaggcagat gtcgtcggcg acggttttat
     1141 tgccgaagcg tttgcagagt ccgttcagtt caagcatggc gtatcctata aacgtatgcc
     1201 gtccagccac tcggacagcg gatgggcggc atcaatcaga ccgtaacggc aaaacgcgtc
     1261 cagcgtaacc agttgcgcgt cgtgcatcat gttttccgac aacatggcat ccaacagacc
     1321 gccgatgtcc atcttttcaa aacacgcaac ctcgccgtcc tgattttcag gcaggaaggt
     1381 ttcgggcagg atggcatcga atacatacag gatttcattg tgcacacccc ggctgacggg
     1441 gcgcaggctg tgcagccgag ataccggacg gataaacggg aacagcgttt tatccaaacc
     1501 ggcttcttcg ctgctttcgc gacacacggt ttcagacggc aattcaccgc tggaaacacc
     1561 gccggcggca gtattgtcga gtttgtcggg atcgactgct ttgtgcggac tgcgcctgcc
     1621 tatccagaaa tgccatcggc cgtccgattc ggtcagaccg ttgagatgga cggcgcggct
     1681 gagtagtccg aacgggcgga aagcggcgcg ttcgagcgtg aacaaggggt tgccgccgcc
     1741 gtcggtcagg tcgaaacact cgttgcgcca gccgtgaagc agccccgcct tgttccatgt
     1801 gcgggcgagg tgctgcaagc gtccgcccat atccgtccag ccgtccgcat tcagaaaaat
     1861 gccgtctgaa gactccgagc agcctgcctc ccagtctttt ttgacgcgct ccgcccattc
     1921 cggcgacaga ttgcccaaag gcagacggtt cagatacagc gttttccagc aactttttgc
     1981 accgtaactt gcttttgccc actcgaacag ggcatcaagg tcttgtttgc tgacggattc
     2041 ggtaaaacgg acggtcggca tagtcggctt tcttgaacat aatgcggaag attgtagcca
     2101 aaccgcctga atttgcaacc gcaaacagac ggcgggctgc cgttccgata ttgcggcagg
     2161 aaggaaaatc cggcaaaaaa cggaggcggc aggaaacagg aaacaggcaa aacaaaaccc
     2221 ctcggcattg aaccgagggg tttaatattt ggttgcggga gcaggattcg aacctacgac
     2281 cttcgggtta tgagcccgac gagctaccat gctgctccat cccgcgtcag aagatggaac
     2341 tatacggcag attttttatg ttgtcaaaca ttatttccgc gaaaaatcat aaaattttgc
     2401 cgtccggcgg tttatgcctg atttgaaata tcattttctt tacaaaagtt catgttcgtg
     2461 atttaatttt ggttaacatt gaaacagggg tgctgcatga tgttcaggcg gctgagaaat
     2521 accctttaca cccgatctgg ataatacctg cgtggggagt tttcacggat tctgcctttc
     2581 agacggcatt ttttgatact cgggccgttt gaaaaagcaa agtgctcctg tttctttatt
     2641 ctaaacgaga aaacaggagc attttttatg actacgccaa aaaaaactgc caaaacttcc
     2701 ggcaacgaag cgcgcgaact tgccgacttg agcgaagaca tcggcatccg cttcaaatat
     2761 ccgaactcgg agcgcgtgta tctgcaaggc agccgcgacg acatccgcgt gcctttgcgc
     2821 gaaatccgtc aggacgacac ctacacggcg caaggcacgg aagccaaccc gccgattccc
     2881 gtctatgaca ccagcggcgt gtacggcgat ccggcggcgc acatcgacct gaaacaaggt
     2941 ctgccgcaca tccgcacggc gtggctggac gaacgcggtg ataccgaaat cctgcccaag
     3001 ctttccagcg aatacggcat cgaacgcgca cacgatccga aaaccgccca tctgcgcttc
     3061 aaccaaatca cccgcccgcg ccgcgccaaa gccggccgca acgtaaccca gctccattac
     3121 gcccggcaag gcattatcac gccggaaatg gaatttgtcg ccatacgcga acgtttgaaa
     3181 ttagacgaat tgtcccaaaa accggaatac gccaaactct tgaagcaaca cgcggggcaa
     3241 agtttcggcg cgaacatccc gacccgtccc gatcaaatca cacccgaatt cgtgcgccgg
     3301 gaaatcgccg ccggacgtgc gattattccc gccaacatca accatcccga actcgaaccg
     3361 atgattatcg gccgcaactt ccgcgtcaaa atcaacggca acttgggcaa ttccgccgtc
     3421 acttccagcc tgaccgaaga agtcgaaaaa atggtgtggt cgctgcgttg gggcgcggac
     3481 acaattatgg acttatccac aggcgcgcac atccatgaaa cgcgcgaatg gattatccgc
     3541 aacgcgcccg tccccatcgg caccgtgcct atttatcagg ctttggaaaa aaccggcggc
     3601 attgccgaag atttgacttg ggatttgttc cgcgacacct taatcgagca ggcggaacaa
     3661 ggcgtggact atttcaccat acacgcgggc gtgttgctgc gttatgtacc gatgaccgcc
     3721 aaccgcctca ccggcatcgt ctcgcgcggc ggttcgatta tggcgaaatg gtgtttggca
     3781 catcatcggg aaaacttcct ctacacgcat ttcgacgaaa tctgcgaaat catgaaagcg
     3841 tatgatgtgt cgttcagcct cggcgacggc ctgcgccccg gctgcattgc cgatgccaac
     3901 gacgaatccc aattcgccga gctgcacacc ttgggcgaat tgaccgataa agcgtggaaa
     3961 catgacgtac aagtcatgat cgaaggcccc ggccatgtgc cgctgcaacg cgtcaaagaa
     4021 aacatgaccg aagagctgca acactgcttt gaagcacctt tttacacact cggcccgctc
     4081 gttaccgaca tcgcacccgg ctacgaccac atcacctcgg gcataggcgc ggccaatatc
     4141 ggctggtacg gcacggcgat gctttgttac gttaccccca aagaacattt ggggctgccc
     4201 gacaaagaag acgtgcgcac cggcatcatc acctacaaac tcgccgccca cgccgccgat
     4261 ctcgccaaag gctggccggg cgcacaatta cgtgacaacg ccctgagcaa ggcgcgtttc
     4321 gagttccgtt ggcgcgacca atttcgctta agccttgacc ctgaacgtgc cgagagcttc
     4381 cacgacgaaa ccctgcctgc cgaaggcgcg aaaatcgccc acttctgctc aatgtgcggc
     4441 cccaaattct gctcgatgaa aatcacgcag gaagtgcgcg actacgccga caagcaaaaa
     4501 gcccaacggc agggcatgga ggaaaaagcg gtcgagttcg tcaaaaaagg cgcgaagatt
     4561 tacagttgaa acgtcaagca aaaaatgccg tctgaaaccc ggaaaaaagg cttcagacgg
     4621 cattctttcg cttgtgaaaa tatagtggat taacaaaaat caggacaagg cgacgaagcc
     4681 gcagacagta cagatagtac ggaaccgatt cacttggtgc ttgagcacct tagagaatc
//
LOCUS       DAXISH010000096         4217 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.096, whole genome shotgun sequence.
ACCESSION   DAXISH010000096 DAXISH010000000
VERSION     DAXISH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4217
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.096"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            205..1677
                     /gene="pyk"
                     /locus_tag="ACFOV4_001984"
     CDS             205..1677
                     /gene="pyk"
                     /locus_tag="ACFOV4_001984"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFC7619922.1"
                     /translation="MNQTSRDLTRISHNTKIVATLGPGSNNVELLEDMIRVGGLNVVR
                     FNFSHGTPEFHQENARIVREAAKRAGQEIAIIADLQGPKIRVGKIAGGGIELNKGETL
                     VLDAALEGEGTREAVGLDYRDLPDDVAAGDVLWLDDGLLTLTVESVEGSRIITRVENS
                     HVLKSNKGINKRGGGLSAGALTEKDFRDLKTAIAIGCDYLAISFVKSAEDLHIARAKV
                     EEEMKGSTAVRPGLVSKIERVEAIENLDEIILAGDGIMVARGDLAVEVGHAAVPALQK
                     RMIRRARELRRFSITATQMMESMITNPVPTRAEVSDVANAVLDGTDAVMCSAETAVGA
                     YPFETVSQMAIICAAAEKEQDSLNGVAEQAEYPEAVSTNLAVAGGAVSVARAVHAKAI
                     VALTESGSTAFEISRHNITLPIFALTPSVSAQRRMAMYRGVRPLILATSTDHDTALNE
                     VETMLVEHNILHSGDQYIITSGSQMRESGSTNTLEVLRVK"
     gene            1985..3385
                     /locus_tag="ACFOV4_001985"
     CDS             1985..3385
                     /locus_tag="ACFOV4_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpP1/FadL family transporter"
                     /protein_id="HFC7619923.1"
                     /translation="MTPSALKKTVLLLGTAFAAASAQASGYHFGTQSVNAQSTANAAA
                     AEAADASTIFYNPAGLTKLDSSQISVNANIVLPSIHYEADSATDFTGLPVQGSKSGKI
                     TKTTVAPHIYGAYKVNDNLTVGLGVYVPFGSATEYEKDSVLRHNINKLGLTSIAVEPV
                     AAWKLNDRHSFGAGIIAQHTSAELRKYADWGIKSKAEILTAKPPKPNGVAEAAKIQAD
                     GHADVKGSDWGFGYQLAWMWDINDRARVGVNYRSKVSHTLKGDAEWAADGAAAKAMWS
                     TMLAANGYTANEKARVKIVTPESLSVHGMYKVSDKADLFGDVTWTRHSRFDKAELVFE
                     KEKTIVNGKSDRTTITPNWRNTYKVGFGGSYQISEPLQLRAGIAFDKSPVRNADYRMN
                     SLPDGNRIWFSAGMKYHIGKNHVVDAAYTHIHINDTSYRTAKASGNDVDSKGASSARF
                     KNHADIIGLQYTYKFK"
     gene            complement(3752..4045)
                     /locus_tag="ACFOV4_001986"
     CDS             complement(3752..4045)
                     /locus_tag="ACFOV4_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619924.1"
                     /translation="MKTNDKLNRQIDVLQKQSAAIHNEAYIEMNTLLYRHREVVSVHN
                     RKADYAEKGKERIALFPRGLNGITKLPAAVLLPERPDCFDMKAVWQMFNRIPR"
BASE COUNT         1071 a         1239 c         1070 g          837 t
ORIGIN      
        1 taaatttagc ctaagtcata aaaccgtgta attttgcgcc aaaaaaggcg gtttgcaggt
       61 aaaatatcaa actattaatt taaatcatat ttttacagaa tattccgccg cgttcatcaa
      121 atggacatca aaccggttcc aaatttctgt aattttgtaa caaaataccg caaaacaccc
      181 gattgagacc aaaaggactt tcatatgaac cagacaagcc gcgatctgac ccgcatcagc
      241 cacaacacta aaatcgtcgc cacccttggg ccgggcagca acaacgtaga actgttggaa
      301 gatatgatcc gcgtcggcgg cctgaacgtc gtccgcttca acttcagcca cggcacgccc
      361 gaattccatc aggaaaacgc ccgcatcgtg cgcgaggcgg caaaacgcgc cggacaggaa
      421 atcgccatca ttgccgacct gcaagggccg aaaatccgcg tgggcaaaat cgccggcggc
      481 ggcattgaat tgaacaaagg cgaaacgctg gtactggatg ccgcgctcga aggcgaaggc
      541 acgcgcgagg cggtcggttt ggactaccgc gacctgcccg acgacgttgc cgcaggcgac
      601 gtattgtggc tggacgacgg cctgctgacc ctgaccgtgg aatccgtcga aggcagcagg
      661 attatcacaa gggtggaaaa cagccatgtc ctgaaaagca acaaaggcat caacaaacgc
      721 ggcggcgggc tgtccgcagg cgcgttgacc gaaaaagact tccgcgacct gaaaaccgcg
      781 attgccatcg gttgcgacta cctcgccatc agctttgtga aatctgccga agatttgcac
      841 atcgcgcgcg ccaaagtcga agaagaaatg aagggcagca ctgccgtgcg ccccggtttg
      901 gtttccaaaa tcgaacgcgt agaagcgatt gaaaaccttg atgaaatcat cctcgccggc
      961 gacggcatta tggttgcgcg cggcgacttg gcggtcgaag tcggacacgc cgccgtcccc
     1021 gccctgcaaa aacggatgat ccgccgcgcc cgcgagttgc gccgcttcag cattacggcg
     1081 acgcaaatga tggaatcgat gattaccaac cccgtgccga cccgcgcgga agtcagcgat
     1141 gtggcaaacg cggtattgga cggtaccgat gcggtgatgt gttccgccga aaccgccgtc
     1201 ggcgcgtatc cgtttgaaac cgtcagccaa atggcaatta tctgcgcggc tgcggaaaaa
     1261 gagcaggatt cgctcaacgg cgttgccgaa caggcggagt atcccgaagc ggtcagcacc
     1321 aacctggcgg ttgccggcgg cgcggtcagc gtggcgcgcg cggttcacgc caaagcgatt
     1381 gtcgccctga ccgaaagcgg ttcgaccgcc tttgaaatca gccgccacaa catcaccctg
     1441 ccgattttcg cgctgacccc gagcgtttcc gcccaacgcc gtatggcgat gtaccgcggc
     1501 gtgcgcccgc tgattttggc aaccagtacc gaccacgaca cggcgttgaa cgaagtcgaa
     1561 accatgctgg tggaacacaa catcctgcat tccggcgacc agtacatcat caccagcggt
     1621 tcgcaaatgc gcgaatccgg ttcgaccaac acactggaag tgctgcgcgt caaataatcc
     1681 gccctgagtg gaaaatgccg tctgaagccg atgcccgagg cttcagacgg cattttttgc
     1741 ggcggcgcgg cggttcgggc aaactgaaaa aattgtgcaa atccggcaac atcggataaa
     1801 attgagtacc tatactaaag cgaaacaagg catttccgac tgcctttttt atagtggatt
     1861 aaatttaaac cagtacggcg ttgccttgcc gtactatctg tactgtctgc ggcttcgtcg
     1921 ccttgtcctg atttttgtta atccactata tttatccacc gtccgccttt ttacggaaac
     1981 cgaaatgacc ccttccgcac tgaaaaaaac cgtcctactg ctcggcactg cctttgccgc
     2041 cgcatccgca caagcctccg gctaccactt cggcacacag tcggtcaacg cgcaaagcac
     2101 ggcaaatgcc gccgccgcag aagccgccga cgcatcgacc atcttctaca accctgccgg
     2161 cctgaccaaa ctcgacagca gccagatttc cgtcaacgcc aacatcgtgc tgcccagcat
     2221 tcattatgag gcggattccg ccaccgactt taccgggctt cccgtccaag gttcgaaaag
     2281 cggcaaaatc accaaaacca cggtcgcgcc ccacatctac ggcgcataca aagtcaacga
     2341 caatctgacc gtgggcttgg gcgtgtacgt ccccttcggc tctgccaccg aatacgaaaa
     2401 agattccgtg ttgcgccaca acatcaacaa actcggtctg accagcatcg ccgtcgaacc
     2461 tgtcgccgca tggaaactca acgaccgcca ttccttcggc gcaggcatca tcgcccaaca
     2521 tacttccgcc gaactgcgca aatatgccga ctgggggatt aagagtaaag cagagatatt
     2581 gacggcaaaa ccgcccaaac ctaacggtgt agccgaagct gcaaaaattc aggccgacgg
     2641 acacgccgat gtcaaaggca gcgattgggg cttcggctac caactggcgt ggatgtggga
     2701 catcaacgac cgcgcgcgcg tgggcgtgaa ctaccgttcc aaagtctcgc acacgctcaa
     2761 aggcgatgcc gaatgggcgg cagacggcgc ggcggcgaaa gcaatgtgga gtacgatgct
     2821 tgcagcaaac ggctacacgg cgaatgaaaa agcccgcgtt aaaatcgtta cgcctgagtc
     2881 tttgtccgta cacggtatgt acaaagtgtc cgataaagcc gacctgttcg gcgacgtaac
     2941 ttggacgcgc cacagccgct tcgataaggc ggaactggtt tttgaaaaag aaaaaaccat
     3001 cgtcaacggc aaatccgacc gcaccaccat cacccccaac tggcgcaaca cctacaaagt
     3061 cggcttcggc ggttcttatc aaatcagcga accgctgcaa ctgcgcgccg gcatcgcttt
     3121 tgacaaatcg cccgtccgca acgccgacta ccgcatgaac agcctgcccg acggcaaccg
     3181 catctggttc tccgccggca tgaaatacca tatcggcaaa aaccacgtcg tcgatgccgc
     3241 ctacacccac atccacatca acgacaccag ctaccgcacg gcgaaggcaa gcggcaacga
     3301 tgtggacagc aaaggcgcgt cttccgcacg tttcaaaaac cacgccgaca tcatcggcct
     3361 gcaatacacc tacaaattca aataaacggc ccgccgtttg attgtagaaa tgccgtctga
     3421 aacagatttc cgtttcagac ggcattgttt taggcgcgat ttatagtgga ttaacaaaaa
     3481 tcagaacaag gcgacgaagc cgcagacagt acaaatagta cggaaccgat tcacttggtg
     3541 cttcagcacc ttagagaatc gttctctttg agctaaggcg agacaacgcc gtactggttt
     3601 ttgttaatcc actataaaac gaagcaggaa aacactgccg ctatcaccgt acagacagga
     3661 atgacggggt gcattttgat ttgttccact gcaacaatgc cgtctgaacg cttccgtttc
     3721 agacggcatt tttatccggc agacgatacg cctacctcgg tattctatta aacatttgcc
     3781 aaactgcctt catatcaaaa caatcgggac gctcgggcaa caggacggcg gcaggcagct
     3841 tggtgatgcc gttcaagccg cgcgggaaca gcgcaatccg ctctttgccc ttttccgcat
     3901 aatccgcctt gcggttgtgg acggaaacca cttcgcggtg gcggtaaagc agcgtgttca
     3961 tttcgatata ggcttcgttg tggatggctg ccgactgttt ctgcaacacg tcaatctgcc
     4021 tattgagctt gtcgttggtt ttcatcagcc tgttgaagaa cgacggttac tcctgcagtt
     4081 tgacggtaca ggcttcgata ctttccgata ccggcccgaa ctgttcgagg tatttttcca
     4141 aacagttttc caagtcggtt aggcagccgg ccatcttgcg ggaaaattct tcttcaggct
     4201 ttccctgccg aatggac
//
LOCUS       DAXISH010000097         4207 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.097, whole genome shotgun sequence.
ACCESSION   DAXISH010000097 DAXISH010000000
VERSION     DAXISH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4207
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.097"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(598..1023)
                     /locus_tag="ACFOV4_001987"
                     /pseudo
     CDS             complement(598..1023)
                     /locus_tag="ACFOV4_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686491.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
     gene            1165..1617
                     /gene="dut"
                     /locus_tag="ACFOV4_001988"
     CDS             1165..1617
                     /gene="dut"
                     /locus_tag="ACFOV4_001988"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFC7619925.1"
                     /translation="MNIEVEMKVLDERMADFIPTYATAGSAGLDLRACLDEEVVLQPG
                     ETFLVPTGLAIYLANPSYAAVLLPRSGLGHKHGIVLGNLVGLIDSDYQGELKVSLWNR
                     SSEPFAVKPFERIAQMVIVPIVQARFKRVEEFVGSSRGEGGFGSTGLH"
     gene            1694..2881
                     /gene="dapC"
                     /locus_tag="ACFOV4_001989"
     CDS             1694..2881
                     /gene="dapC"
                     /locus_tag="ACFOV4_001989"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009016 - succinyldiaminopimelate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyldiaminopimelate transaminase"
                     /protein_id="HFC7619926.1"
                     /translation="MNTLLNQLKPYPFARLREAMQGISAPEGLEAVPLHIGEPKHPTP
                     KVITDALTASLHELEKYPLTAGLPELRQACANWLKRRYDGLTLNSDTEILPVLGSREA
                     LFSFVQTVLNPVSDGIKPVIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSI
                     SEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSEIYFDGNK
                     PLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSA
                     MSIPVQRASIAAWDDEQHVIDNRRLYQEKFERVIPILQQVFDVKLPDASFYIWLKVPD
                     GDDLAFARNLWQKAAIQVLPGRFLARDTEQGNPGEGYVRIALVADVATCVKAAETIVS
                     LYR"
     gene            3044..3823
                     /gene="yaaA"
                     /locus_tag="ACFOV4_001990"
     CDS             3044..3823
                     /gene="yaaA"
                     /locus_tag="ACFOV4_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HFC7619927.1"
                     /translation="MFFVLSPAKNLNEKDPAPVSEFTQPDLLAESEILMQQLRELALQ
                     QIAELMHVSDKIALLNAQRNAEWHTPFTPENAKQAVFMFNGDVYEGMDANTLDIGQIR
                     YLQNHVRLLSGLYGLLRPLDLIQPYRLEMGTAFANLRGKNLYEFWGDIITNLLNDTLA
                     QAGSNTLVNLASQEYFKSVNTKTLRAQLITPIFKDEKNGKYKIISFYAKRARGLMVRY
                     AAEHHITDPEMLKNFNYEGYAFNDAASNESEWVFMRSEQIK"
     gene            3906..3996
                     /locus_tag="ACFOV4_001991"
     tRNA            3906..3996
                     /locus_tag="ACFOV4_001991"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3940..3942,aa:Ser,seq:tga)
     gene            4074..4163
                     /locus_tag="ACFOV4_001992"
     tRNA            4074..4163
                     /locus_tag="ACFOV4_001992"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4108..4110,aa:Ser,seq:cga)
BASE COUNT         1087 a         1009 c         1012 g         1099 t
ORIGIN      
        1 gaatccatcc atacggaaac ctgcatcccg tcattcccac gaacctacat tccgtcattc
       61 ccacgaaagt gggaatccag ttttttgagt ttcagtcatt tccgataaat tgccttagta
      121 ttgaatgtct agattcccgc ctgcgcggga atgacgaatc catccgtacg gaaacctgca
      181 ccacgtcatt cccacgaacc tacattccgt cattcccacg aaagtgggaa tccagttttt
      241 tgagtttcag tcattcccga taaattgcct tagcattgaa tgtctagatt cccgcctgag
      301 cgggaatgac gaatccatcc atacggaaac ctgcaccacg tcattcccac gaaagtggaa
      361 atctaggatg cagggtttgg gaaaccgtgt tatccgataa gtttccgcac cgacaggtct
      421 agattcccgc ctgcgcggga atgacgattc atatagtgga ttaacaaaaa tcaggacaag
      481 gcggcgaagc tgcagacagt acagatagta cggaaccgat tcacttggtg cttcagcacc
      541 ttagagaatc gttctctttg agctaaggcg aggcaacgct gtactggttt ttgttaatcc
      601 actataaaaa ggcatattga atgcgggtaa accggttgct ttccgttttt ggatttcgga
      661 gaatgccatc gcccagcttt catcacacat aaaaaacagt gcgggcacgg cttttttcag
      721 cggtatttct ttcaggtgca gggcaagtgc cgcccccatc aggatatgcc gcgaattaat
      781 cataaaggtt acggtggcga taagcagtat cggcagaggt tccgcccaca ggttgaccgt
      841 ggcaaactcg gagccgccgg cgaagttcat accggtcatc aacaacattt ccagccagct
      901 catgcctttt tgtccaccct gcataccgag tattaatgcc caaggcagaa gtccgataag
      961 tatgggcgaa ctttctttga tggcgcgtat aaattcgtta tgcggggaag gtgtgtgcat
     1021 aatgttcgtc ttcataacgg gaagggcggg cattatacac tggcaacgga tttcaaaaca
     1081 aaaccgattt gccgtgtttc agcgtaaaca cggcttgtgt ataatctccc atctttgaaa
     1141 ccggccgtat gcaggagcaa gacgatgaat attgaagtag aaatgaaagt gttggacgag
     1201 aggatggcgg attttatccc tacctatgcg acagcgggtt ctgccggttt ggacttgcgc
     1261 gcctgtttgg atgaggaagt cgtcttgcag ccgggggaaa cgtttcttgt gccgacaggt
     1321 ttggcaattt atttggccaa tccttcatat gccgccgttt tgctgccccg ttccggcttg
     1381 gggcataaac acggcattgt tttgggcaat ttggtcggtt tgattgactc cgattatcaa
     1441 ggggaattga aggtgtcgtt atggaacaga agcagcgaac cgtttgccgt caagccgttt
     1501 gagcgtatcg cgcagatggt tatcgttcca atcgtgcagg cgcgtttcaa acgtgtcgaa
     1561 gaatttgtcg gaagcagccg tggagaaggc ggtttcggca gtacgggttt gcattgaata
     1621 taaaatgccg tctgatgggt gccgtcaggt tcagacggca tatcttccga tataccgaca
     1681 accggagaac attatgaata ccttactcaa ccaactcaaa ccctatccct ttgcccgact
     1741 gcgtgaagcg atgcagggca tttccgcccc cgaaggtctg gaagccgtcc cactgcatat
     1801 cggcgaaccg aaacatccaa caccgaaagt cattacagat gcgctgaccg cctcattgca
     1861 cgagttggaa aaatatccgc tgacggccgg tttgcctgaa ctgcgtcagg cgtgtgcgaa
     1921 ctggttaaaa cgccgttatg atgggttgac gctgaattcc gacaccgaaa ttctgccggt
     1981 tttgggcagt agggaggcgt tgttttcttt tgtccaaacc gtgttgaacc ctgtttcaga
     2041 cggcatcaaa cccgtaatcg tcagcccgaa tcccttttat cagatttatg aaggtgcgac
     2101 acttttgggc ggcggtgaaa tccattttgc caattgcccc gcgccgtctt tcaaccccga
     2161 ttggcgtagt atttccgaag aggtttggaa acgcaccaaa ctggtgttcg tctgctcgcc
     2221 caacaacccc agcggcagcg tgctggattt ggatggatgg aaagaagttt ttgatttaca
     2281 ggataaatat ggtttcatta ttgcctcgga tgaatgctat tccgaaatct atttcgacgg
     2341 caacaaacct ttaggctgcc tgcaggccgc tgcacagttg ggtcgaagca ggcaaaaact
     2401 gcttatgttc accagtttgt ccaagcgttc caacgttccg ggcctgcgtt ccggttttgt
     2461 cgccggcgat gccgaactgc ttaaaaactt tctgctttac agaacctatc acggcagtgc
     2521 aatgagcatt cccgtgcagc gcgcaagcat tgccgcttgg gatgacgaac agcacgttat
     2581 cgacaaccgc cgcctgtatc aggaaaaatt tgagcgcgtt attcccattt tgcaacaggt
     2641 atttgatgtt aaattaccag atgcctcgtt ttacatttgg ttgaaagtcc ccgatggcga
     2701 cgatttggca tttgcacgca atttatggca aaaagccgct atccaagtat tgcctggacg
     2761 ttttttggca cgggataccg aacagggcaa tcccggggaa ggttatgtgc gtattgcttt
     2821 ggttgccgat gtcgcaactt gtgtcaaagc tgcggaaacc attgtttccc tatatcggta
     2881 aagaataaaa aataccgtct gaacttttgt tcagacggca tttttcaata ttttacggtt
     2941 gaatttgcta taacggtatt tacttcactt ttaatctaat cggcttgccc gcaaacacgt
     3001 ttaaacttaa aatccccgtg tttgacacaa taccgagcag attatgtttt ttgtcctttc
     3061 ccctgcgaaa aaccttaacg aaaaagaccc tgcccctgtc agcgagttta cccaacccga
     3121 cctgctggca gagtccgaaa ttctaatgca gcagctgcgc gagcttgcgt tgcaacagat
     3181 tgccgaactg atgcacgttt ccgacaaaat tgccctctta aacgcgcagc gcaatgcaga
     3241 atggcacacg ccgtttacgc cggaaaacgc caaacaggcg gtctttatgt tcaacggcga
     3301 tgtttacgaa ggtatggatg caaacacatt ggatattgga cagatacgct atctgcaaaa
     3361 ccatgtccgc ctgctgtccg gtctatacgg tcttcttcgc ccgttagacc tgatacagcc
     3421 ctatcgtttg gaaatgggga cggcatttgc caatttgcgc ggcaagaatt tgtatgagtt
     3481 ttggggcgac atcattacca accttttaaa tgacacgctt gcccaagcag gcagcaatac
     3541 gcttgtcaac cttgcctcac aggaatattt caagtccgtc aacacgaaaa cacttcgggc
     3601 gcagctgatt accccgatat ttaaagacga aaaaaacggt aaatataaaa tcatcagttt
     3661 ctatgccaag cgtgcgcgcg gattaatggt gcgctatgcg gcagaacatc atattaccga
     3721 ccctgaaatg ctgaaaaatt ttaattacga aggctacgca ttcaatgacg cggcttcaaa
     3781 tgaaagcgaa tgggttttta tgcgttcgga acaaataaag tgaaaacaat aaattaagta
     3841 ttttccgaaa aaagtgcttg gcaaaatgta taaacttcat tattattctt cttcttcaag
     3901 aagacggaag cgtggcagag cggtttaatg caacggtctt gaaaaccgtc gagggttgat
     3961 agccctccgt gagttcgaat ctcaccgctt ccgccaatcc ttggggtcaa aaaccaaata
     4021 aaaatgaagt agcataaagc atcggcattt ttatttggtt ttacttcatt atcggaaacg
     4081 tggcagagag gctgaatgca gcggactcga aatccgctga gggtgcaaat cctccgtggg
     4141 ttcgaatccc accgtttccg ccacaaaaca aaaccgccct gattcggggc ggttcttttt
     4201 tgttcaa
//
LOCUS       DAXISH010000098         4054 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.098, whole genome shotgun sequence.
ACCESSION   DAXISH010000098 DAXISH010000000
VERSION     DAXISH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4054
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.098"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            339..1856
                     /locus_tag="ACFOV4_001993"
     CDS             339..1856
                     /locus_tag="ACFOV4_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein assembly modifier"
                     /protein_id="HFC7619928.1"
                     /translation="MLYFRYGFLVVWCAAGVSAAYGADAPAILDDKALLQVQRSVSDK
                     WAESDWKVENDAPRVVDGDFLLAHPKMLEHSLRDALNGNQADLIASLADLYAKLPDYD
                     AVLYGRARALLAKLAGRPAEAVARYRELHGENAADERILLDLAAAEFDDFRLKSAERH
                     FAEAAKLDLPAPVLENVGRFRKKTEGLTGWRFSGGISPAVNRNANNAAPQYCRQNGGR
                     QICSVSRAERAAGLNYEIEAEKLTALADNHYLLFRSNIGGTSYYFSKKSAYDDGFGRA
                     YLGWQYKNARQTAGILPFYQVQLSGSDGFDAKTKRVNNRRLPPYMLAHGVGVQLSHTY
                     RPNPGWQFSVALEHYRQRYREQDRAEYNNGRQDGFYVSLAKRLGESATVFGGWQFVRF
                     VPKRETVGGAVNNAAYRRNGVYAGWAQEWRQLGGLNSRVSASYARRNYKGIAAFSTEA
                     QRNREWNVSLALSHDKLSYKGIVPALNYRFGRTESNVPYAKRRNSEVFVSADWRF"
     gene            complement(1915..3696)
                     /locus_tag="ACFOV4_001994"
     CDS             complement(1915..3696)
                     /locus_tag="ACFOV4_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate-binding protein"
                     /protein_id="HFC7619929.1"
                     /translation="MPYFALFDDAVSGRAKRYQNHVESRFFRPEELDALDGALQSGWQ
                     KGLHAVLFADYGFGLPLTGVESERGGNLALHWFADCADTDAASWLARHSDGLPAGIST
                     PQSSVSEADYLDHIRQIHEAIRRGDTYQINYTTRLHLQAYGNPVKLYQRLRQPVPYAV
                     LSHLPDAQGQSAWTLCFSPELFLKIGSDGTISTEPMKGTAPILGDGQDERRAAELQAD
                     PKNRAENVMIVDLLRNDLGKIAQTGTVCVPEPFKVSRFGSVWQMTSTIQAQALPHTSF
                     ADILRAAFPCGSITGAPKKMSMQIIESLEAEPRGLYTGSIGYLNPSSGGLGFEGAFNV
                     VIRTLSLTPLSDGIYQGVYGVGSGIVIDSDPAAEYRECGWKARFLNELRPDFGIFETL
                     RVENRQCALLDRHLCRLKTSAQALNLPLPDGCENQIKQYIAHLPDGVFRVKARLASDG
                     ISLSRAVLNRLTDKQRVIISPAVLPAQNYLRRFKTTHRALFDQAWQTAETQGAFDSLF
                     FNSDGILLEGGRSNVFVKHRGQWLTPSLDLDILNGIMRQAVLDEPQKYLQTNQVIETH
                     ITQKTLQEAEEIRLSNALRGVFAAALA"
BASE COUNT          850 a          901 c         1325 g          978 t
ORIGIN      
        1 cttttgcggg aatgacggcg acagggttgc tgttatagtg gatgaacaaa aaccggtacg
       61 gcgttgtctc gccttagctc gaagagaacg attctctaag gtgctgaagc accaagtgaa
      121 tcggttccgt actatctgta ctgtctgcgg cttcgtcgcc ttgtcctgat ttttgttaat
      181 ccactataaa tgtgaaatcc gccctttgaa aatcgggcgg cggttttttg cctgcccgct
      241 ttcagacggt aaagccggtt ttcacgggtt tctgcctgtt tttcggatgg tttgacgtgc
      301 ttcggcggcg tgtttgccag aaaggtaaat gacagggtat gttgtatttc agatacggtt
      361 ttttggttgt ttggtgtgcg gcaggtgttt ctgccgccta tggggcggat gcgcccgcga
      421 ttttggatga caaggcattg ttgcaggtgc agcggtcggt gtcggataag tgggcggaat
      481 cggattggaa agttgaaaat gatgccccgc gcgtggttga cggggatttt ttgttggcgc
      541 acccgaaaat gttggaacat agtttgcgcg acgcgctcaa cggcaatcag gcggatttga
      601 tcgcttcgtt ggcggatttg tatgccaagc tgccggatta tgacgcggtt ttgtacggca
      661 gggcgcgggc tttgctggcg aaattagcgg gaaggccggc ggaggcggtg gcgcggtatc
      721 gggaactgca cggggaaaat gcggcagacg agcggatttt gctggatttg gcggcggcgg
      781 agtttgacga tttccgactg aagtcggcag aaaggcattt tgcggaggcg gcaaaattgg
      841 atttgccggc gccggttttg gaaaatgtgg ggcgttttcg gaaaaaaacg gaggggctga
      901 cgggctggcg tttttcgggc ggcatcagcc cggcggtcaa tagaaatgcc aataatgccg
      961 cgccgcagta ttgccggcaa aacggaggcc ggcagatatg cagtgtcagc cgggcggagc
     1021 gggcggcagg gttgaattat gaaatcgagg cggaaaaact gacggcgttg gcagataatc
     1081 attatttgtt gttccgttcc aatatcggcg gcacgagcta ttatttcagt aaaaaatcag
     1141 cttatgatga cgggttcggc agggcgtatt tgggttggca gtataaaaat gcgcggcaga
     1201 cggcggggat tttgccgttt tatcaggtgc agttgtcggg cagcgacggc tttgatgcga
     1261 aaacaaaacg ggtaaacaac cgccgcctgc cgccgtatat gctggcgcac ggagtcggcg
     1321 tgcagctgtc ccatacttac cgcccaaacc cgggatggca attttcggtc gcgctggaac
     1381 attaccgcca acgctaccgc gaacaggata gggcggaata caataacggc cggcaggacg
     1441 ggttttatgt ttcgttggca aaacgtttgg gtgaatcggc aactgtgttc ggcggctggc
     1501 agtttgtgcg gtttgtgccg aaacgtgaaa cggtgggcgg cgcggtcaat aatgccgcct
     1561 accggcgcaa cggtgtttat gccggttggg cgcaggagtg gcggcagttg ggcggtttga
     1621 acagtcgggt ttctgcgtct tatgcccgcc gcaactataa gggcattgcg gctttctcga
     1681 cagaggcgca acgcaaccgc gaatggaatg tctcgctggc tttgagccac gacaagttgt
     1741 cgtacaaagg tatcgtgccg gcgttgaatt atcgtttcgg caggacggaa agtaatgtgc
     1801 cgtatgcgaa acgccgcaac agcgaggtgt ttgtgtcggc ggattggcgg ttttgaatgg
     1861 tgggataatg ccgtccgaac tttggaaaca ggttcggacg gcatttttgc gcgttcaggc
     1921 aagggcggcg gcaaatacgc cgcgcagggc gttggagagg cggatttctt cggcttcttg
     1981 cagtgttttt tgtgtgatgt gtgtttcgat tacttgattt gtttgcaaat atttttgcgg
     2041 ttcgtccaat acggcttggc gcattatgcc gtttaaaatg tctaaatcta aagagggcgt
     2101 aagccattgt ccgcgatgtt tgacgaacac gttgcttctg ccgccttcga gcaggatgcc
     2161 gtccgaattg aaaaacaggc tgtcgaacgc gccttgtgtt tcggcggttt gccacgcttg
     2221 gtcgaagagg gcgcggtgtg tggttttgaa gcggcgcagg tagttttgtg cgggcaggac
     2281 ggcgggcgaa atgatgacgc gttgtttgtc ggtcagacgg tttaaaacgg cgcgggacag
     2341 gctgatgccg tctgaagcga gccgggcttt gacgcggaac acgccgtcgg gcaaatgggc
     2401 gatgtattgt ttgatttgat tttcgcaacc gtcgggcagg ggcaggttga gggcttgggc
     2461 ggaggttttc agacggcata ggtggcggtc gagcagggcg cattgcctgt tttccacgcg
     2521 cagggtttca aaaatgccga agtcggggcg caattcgttg aggaaacggg ctttccagcc
     2581 gcattcccga tattcggcgg cagggtcgct gtcgatgacg atgccggaac cgacaccgta
     2641 cacgccttga taaatgccgt ctgaaagcgg cgtgagcgat aaggtgcgga tgacgacgtt
     2701 gaacgcgcct tcaaacccca agccgccgga actcgggttc aaatagccga tgctgcccgt
     2761 ataaagtccg cgcggttcgg cttcgagcga ttcgataatc tgcatactca tttttttggg
     2821 cgcaccggtg atgctgccgc aggggaaggc ggcgcggagg atgtcggcga acgaggtgtg
     2881 cggcaaggct tgggcttgga tggtgctggt catctgccaa acgctgccga aacgcgatac
     2941 tttaaacggt tcgggtacgc atactgtgcc ggtttgggcg attttgccga gatcgttacg
     3001 cagcaaatcg acaatcatca cgttttcggc gcggtttttc gggtctgctt gcaactcggc
     3061 ggcgcggcgt tcgtcttgtc cgtcgcccaa aatcggcgcg gtgcctttca tcggttcggt
     3121 gctgatggtg ccgtccgaac cgattttgag gaagagttcg ggcgagaaac acagcgtcca
     3181 cgcggattgc ccttgtgcat cgggcaggtg ggacaaaacg gcatagggga cgggctggcg
     3241 caggcgttgg taaagtttga cgggattgcc gtaggcttgc aggtgcaggc gggtagtgta
     3301 gttgatttga taggtgtcgc cgcgtcggat ggcttcgtgg atttggcgga tatggtcgag
     3361 gtaatcggct tcggatacgg aggattgcgg cgtggaaatg ccggcgggga ggccgtctga
     3421 gtgtcgggca agccagcttg cggcatcggt gtcggcgcag tcggcaaacc agtgcagggc
     3481 aaggttgccg ccgcgttcgg actcgacccc cgtcagcggc aaaccgaatc cgtagtctgc
     3541 aaacaacacg gcatgcagcc ctttttgcca gcccgattgc agcgcgccgt ccaaagcatc
     3601 gagttcttcg ggacggaaaa aacggctttc cacatgattt tgatagcgtt ttgcgcggcc
     3661 gcttacggca tcgtcaaaca gggcgaaata aggcatggca attcggggca aatgttttga
     3721 ttatacgctc tttttacaca tattttcaga cgattcggca aatatcggca aaatgtaatt
     3781 ttatgtagag aaagtggggg gcgaaggtgt aaaattgtga aaacaaattc cgatttccaa
     3841 cctgaaatac aataaggaga cctttatgac agaccaccag ctgcaaccgt ttgaaaacgt
     3901 agaattaggc gaaaagcaag atcagctcca agtatagtgg attaacaaaa accagtacag
     3961 cgttgcctcg ccttggctca aagagaacga ttctctaagg tgctgaagca ccgagtgaat
     4021 cggtttcgta ctatctgtac tgtctgcgtc ttcg
//
LOCUS       DAXISH010000099         3830 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.099, whole genome shotgun sequence.
ACCESSION   DAXISH010000099 DAXISH010000000
VERSION     DAXISH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3830
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.099"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            48..287
                     /locus_tag="ACFOV4_001995"
     CDS             48..287
                     /locus_tag="ACFOV4_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619930.1"
                     /translation="MNVWDIWGRMVEIYHKYKKPCLVLAVDFVMGMVFIEPNEELCIG
                     RCYAPMSESPDFANAVAMAVAMICIVWIAVLSMTD"
     gene            501..1802
                     /gene="bioA"
                     /locus_tag="ACFOV4_001996"
     CDS             501..1802
                     /gene="bioA"
                     /locus_tag="ACFOV4_001996"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HFC7619931.1"
                     /translation="MPSEHQHTSSLLDFDRTHLLHPYTSMTDPLPVYPVKRAEGVFIE
                     LADGTRLIDGMSSWWCAIHGYNHPVLNQAVETQMKQMSHVMFGGLTHEPAVELGKLLV
                     GILPQGLDRIFYADSGSVSVEVALKMAVQYQQARGLRAKQNMATVRRGYHGDTWNAMS
                     VCDPETGMHHIFGSALPQRYFVDNLTSRFDDEWDEADLQPVRALFEAHHTDIAAFILE
                     PVVQGAGGMYFYHPQYLRGLRDLCDEFDIVLIFDEIATGFGRTGKMFACEHAEVVPDI
                     MCIGKGLSGGYMTLAAAITSQKVTETISRGEAGVFMHGPTFMANPLACAVACASVKLL
                     LSQDWQANIRRIESILKCRLKTAWDIRGVKDVRVLGAIGVIELEKGVDMARFQADCVA
                     QGIWVRPFGRLVYLMPPYIISDGVLTKLADKTVQILKEHSK"
     gene            1799..2446
                     /gene="bioD"
                     /locus_tag="ACFOV4_001997"
     CDS             1799..2446
                     /gene="bioD"
                     /locus_tag="ACFOV4_001997"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HFC7619932.1"
                     /translation="MKGVYFVSGIDTDIGKTVATGVLAKQLLQQGKSVITQKPVQTGC
                     QNIADDIAVHRKIMGKPMQEADKQGLTMPEIFSYPASPHLAARLDGRALDLDKIRTAT
                     QELAAQYEVVLVEGAGGLMVPLTENLLTIDYIRQQGYPVILVTSGRLGSINHTLLSFA
                     ALKQYGIRLYSLVFNHIHDSRDAHIAQDSLSYLKCRLKADFSEAEWMELAKTDAV"
     gene            2413..2643
                     /locus_tag="ACFOV4_001998"
     CDS             2413..2643
                     /locus_tag="ACFOV4_001998"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619933.1"
                     /translation="MDGVGKNRRGIKIGKNMEHLYDEYGNTTPNRRTTNKKDETISSK
                     VTVAAIPVAAPFAIADIVDQDFIQAIMKITGH"
     gene            2667..3053
                     /locus_tag="ACFOV4_001999"
     CDS             2667..3053
                     /locus_tag="ACFOV4_001999"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619934.1"
                     /translation="MKCYIKVVIIVFIMVMTTSCNPCFFATSSCDYSFRKNYPINSDD
                     EYYVKNNTSKETRIADLRYCISYACPEVYQKYQLPDENGDYREIIRRKYKDDYKKGYK
                     NADDVMTCYGKIGECMKNNKGYSTKW"
     gene            3047..3490
                     /locus_tag="ACFOV4_002000"
     CDS             3047..3490
                     /locus_tag="ACFOV4_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619935.1"
                     /translation="MVMFRLLSTALVLLIMQGCYYTTIDNEKCFVAPQSVHCPVSSDI
                     ENVIRKNPNKSINQVRSDIKYCANMYFSNIRELNIPQDFDNYIFMLKEKGIPRNDKEL
                     AYNAVRNMHIICLSSLGGYDYYQKTAEFQKIDYKKEMEKLLNENH"
     gene            3561..>3830
                     /locus_tag="ACFOV4_002001"
     CDS             3561..>3830
                     /locus_tag="ACFOV4_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619936.1"
                     /translation="MITRCFKVVIIVFIMVMTTSCNPCFFATSSCNYPFDDMTIRANN
                     DIEYFVKNNTTNEQRIDDFRSCLSVACPEIYKLYQLPDEKGNYQYI"
BASE COUNT         1057 a          734 c          965 g         1074 t
ORIGIN      
        1 agggctgtaa ccttcaatcg gaatttgttg cctgcgggat atgcggtatg aatgtttggg
       61 atatatgggg caggatggtg gaaatctatc ataagtataa gaagccgtgc ctggttttgg
      121 cggtggattt tgtgatgggt atggtattca tagagccgaa tgaggagctg tgcatcggta
      181 gatgctatgc gcctatgtcg gagtcccctg attttgctaa cgctgttgcg atggctgttg
      241 ctatgatctg tatcgtatgg attgccgttt tgtctatgac tgattgaagc gttgggcgga
      301 ggctgtgtga aacaatattg ggcgttgggt cgtctgattc caatcgggct tggggaatgc
      361 gaaacggtgt gcgcttatac tgcggacgat ttgttgcgtg gttttacgcc cgaaacggat
      421 ggaaaggtgt gggaagcggt ctgtcggagt agaatacgcg ttttgcgttt gaatgcagca
      481 ataagaaaag agagaaactt atgccgtctg aacatcaaca cacatcatca ttgcttgatt
      541 tcgaccgtac ccatctgctc catccctata cttccatgac cgatccgctt cccgtttatc
      601 ctgtcaaacg tgcagaaggg gtgtttatcg aattggcgga cggcacgcgg ctgattgacg
      661 ggatgtcgtc ttggtggtgt gcgatacacg gttacaatca tcccgttttg aatcaggcgg
      721 ttgagacgca gatgaaacag atgtcgcatg tgatgttcgg cggtttgacg catgagccgg
      781 cggtggagct gggcaaattg ttggtcggga ttttgccgca ggggctggat cgtatttttt
      841 atgcggattc gggttcggtt tcggtggaag tcgcgttgaa gatggcggtg caataccagc
      901 aggcgcgggg tttgcgtgca aaacaaaata tggcgacggt gcggcgcggg tatcacggcg
      961 atacttggaa cgcgatgtcc gtctgcgatc cggaaacggg gatgcaccat attttcggca
     1021 gcgcgttgcc gcagcgttat tttgtcgata acctgacaag ccgtttcgac gatgaatggg
     1081 acgaggcgga tttgcagcct gtccgcgcct tgtttgaagc gcatcatacg gacattgccg
     1141 cctttatttt ggaaccggtc gtgcagggcg cgggcggtat gtatttttat catccgcagt
     1201 atcttcgcgg attgcgcgat ttgtgcgacg agtttgatat cgttttgatt tttgatgaaa
     1261 tcgccaccgg attcgggcgc acgggcaaga tgtttgcctg cgaacacgcg gaggtcgtgc
     1321 cggatattat gtgcatcggc aagggtttga gcggcggcta tatgacgctg gcggcagcaa
     1381 tcacttcgca aaaagttacc gaaacgattt cgcgcggaga agcgggcgtg ttcatgcacg
     1441 gcccgacatt tatggcgaac ccgctggcgt gtgccgttgc ctgcgcttcg gtcaaactgc
     1501 ttttgtccca agattggcag gcaaatatcc gccgcatcga aagcatctta aaatgccgtc
     1561 tgaaaaccgc gtgggacatt cgtggtgtga aagacgtgcg cgttttgggc gccatcggcg
     1621 tgatcgagtt ggaaaaaggc gtggatatgg cgcgttttca agcggattgc gtggcgcagg
     1681 gcatttgggt gcgcccgttc ggcaggttgg tgtatctgat gccgccttac atcatttcag
     1741 acggcgtttt gaccaaactt gccgacaaaa ccgtgcaaat cttgaaggaa cacagcaaat
     1801 gaaaggcgtt tacttcgtca gcggcataga cacggacatc ggcaaaaccg tcgccaccgg
     1861 cgtgttggca aaacaattgt tgcagcaggg caaaagcgtg attacgcaaa agcccgtgca
     1921 aaccggttgc caaaacattg ccgacgacat cgccgtccat cgtaaaatca tgggtaaacc
     1981 catgcaggaa gccgacaaac aagggctgac catgcctgaa atcttcagtt atccagcttc
     2041 gcctcatctc gctgcccgtc ttgacggcag ggctttggac ttggacaaaa tccgcaccgc
     2101 cacacaagaa ttggcggcgc agtacgaagt cgttttggtc gaaggcgcgg gcggattgat
     2161 ggttccgctg acggaaaacc tgttaaccat tgattatatc cgtcagcaag gctatcccgt
     2221 catcctcgtt accagcggac ggcttggcag tatcaaccac actttactca gtttcgcagc
     2281 gctcaaacaa tacggcattc gcttgtacag cctcgtgttc aaccacatcc acgacagccg
     2341 cgacgcacac atcgcccaag acagcctgag ctacttgaaa tgccgtctga aagccgattt
     2401 ttccgaagcg gaatggatgg agttggcaaa aacagacgcg gtataaagat tgggaaaaat
     2461 atggaacacc tatatgatga atatggaaat acaacgccaa atagaagaac aacaaataaa
     2521 aaagatgaaa ctatttcaag taaagtaact gttgcagcga taccagtagc cgctccattt
     2581 gctattgctg atatagtcga tcaggatttt atccaagcga ttatgaaaat tactggtcat
     2641 tgattatcta tatattggtg gttgttatga aatgctatat taaagttgtc attattgttt
     2701 ttataatggt aatgacaact tcttgtaatc cttgcttttt tgcaacttct tcttgtgatt
     2761 attcttttag aaaaaactat cctataaata gcgacgatga atattatgtt aagaataata
     2821 cgagcaaaga aacaagaatt gcggatttac gctattgtat ttcttatgca tgtccagaag
     2881 tttatcaaaa atatcaacta ccagatgaaa atggagatta tagggagatt attcgtagaa
     2941 aatataaaga tgattataaa aagggctata agaatgcaga tgatgtcatg acatgctacg
     3001 gaaagattgg agaatgcatg aaaaataata aaggatattc aacaaaatgg taatgttccg
     3061 cttattatca acagcccttg tattgttgat aatgcagggc tgttattaca caactattga
     3121 taatgaaaaa tgctttgttg ccccacaaag cgttcattgt cctgtaagtt ctgatattga
     3181 aaatgttatt agaaaaaatc ctaataaaag cataaatcaa gttaggagtg atattaaata
     3241 ttgtgctaat atgtattttt ccaatatacg ggaattaaat attccgcaag attttgataa
     3301 ttacattttc atgcttaaag aaaaaggtat tccaagaaat gataaggaat tggcttataa
     3361 tgcagttaga aatatgcaca ttatttgttt gagttctttg ggtggttatg attattatca
     3421 aaaaaccgca gaatttcaga aaatagatta taaaaaagaa atggagaaat tgttaaatga
     3481 aaaccattaa atttgctatt gccgatatag ttgatagcga ctttatccaa gtgattatga
     3541 aattaagcgg gcattgattt atgattacgc gttgttttaa agttgtcatt attgttttta
     3601 taatggtaat gacaacttct tgtaatcctt gcttttttgc aacttcgtct tgtaattatc
     3661 cttttgatga tatgacgata agagcaaaca acgatattga atattttgtt aaaaataata
     3721 cgactaacga acaacgaatt gatgatttca gaagttgcct ttccgttgct tgtcctgaaa
     3781 tatataaatt atatcaatta cctgatgaaa agggtaatta tcaatatatt
//
LOCUS       DAXISH010000100         3686 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.100, whole genome shotgun sequence.
ACCESSION   DAXISH010000100 DAXISH010000000
VERSION     DAXISH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3686
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.100"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(166..384)
                     /locus_tag="ACFOV4_002002"
     CDS             complement(166..384)
                     /locus_tag="ACFOV4_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619937.1"
                     /translation="MNEYTFSYRFNGKSWSLSIWADNPEEARAKFRAARENAHYDGEV
                     VAKVYTFVNISWVKKLYKRTKYLMGIKE"
     gene            397..567
                     /locus_tag="ACFOV4_002003"
     CDS             397..567
                     /locus_tag="ACFOV4_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HFC7619938.1"
                     /translation="MYFEIYKDAKGEYRWRLKAANHEIIAQGEGYTSKQNCQHAVDLL
                     KSTTAATPVKEV"
     gene            complement(612..917)
                     /locus_tag="ACFOV4_002004"
     CDS             complement(612..917)
                     /locus_tag="ACFOV4_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619939.1"
                     /translation="MSLLKTVKMQAAVVLTALAITACSSTSAPSATEIKVVEKAVMPT
                     PPAALMVAPVRPNPPKDGKTATLLEHAAEFGGYVAELENQNQAWRDWAGNHSRKVGN"
     gene            complement(814..1233)
                     /locus_tag="ACFOV4_002005"
     CDS             complement(814..1233)
                     /locus_tag="ACFOV4_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619940.1"
                     /translation="MNLVKLLANNWQPIAIIALVGTGLAVSHHQGYKSAFAKQQVVIE
                     KMKRDKAQAMLLSAQNYARELEQARAEAKKYEVKAHAVGMALAKKQAEVSRLKTENKK
                     EIENVLTQDRKNAGGGCIDGFGHHGLQLYKRALGYGN"
     gene            complement(1205..1441)
                     /locus_tag="ACFOV4_002006"
     CDS             complement(1205..1441)
                     /locus_tag="ACFOV4_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619941.1"
                     /translation="MRILDIFKNPATGNVSHSKLWANVACAAGTFKFVMLPDPSAEIW
                     AVYLGIVGGYAVARSLVSVKRQEVENESRETASE"
     gene            complement(1444..1608)
                     /locus_tag="ACFOV4_002007"
     CDS             complement(1444..1608)
                     /locus_tag="ACFOV4_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619942.1"
                     /translation="MGQVAFYEKMIGLWSAKSREASEQADLAAFEFAEGELANYQEML
                     KRHLQTKSVE"
     gene            complement(1611..1817)
                     /locus_tag="ACFOV4_002008"
     CDS             complement(1611..1817)
                     /locus_tag="ACFOV4_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619943.1"
                     /translation="MNIIGKLKEAASYFLTKLIGENPSNEQVNRALIQMPNVRPIHTY
                     PRPNLRNSGVAAAKRAARKRKNRR"
     gene            complement(1814..2452)
                     /locus_tag="ACFOV4_002009"
     CDS             complement(1814..2452)
                     /locus_tag="ACFOV4_002009"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFC7619944.1"
                     /translation="MGKTVTLTAGHSNTDPGAVNGSDREADLAQDMRNIVAAILRDDY
                     GLTVKTDGTGKGNMPLREAVKLIRGSDVAIEFHTNSAAGGTGKGNMPLREAVKLIRGS
                     DVAIEFHTNSAAGKAATGIEALSTVKNKRWCQVLSKAVAKKTGWKLRGEDGFKPDNAG
                     HHSRLAYAQAGGIVEPFFVSNDTDLALFKTTKWGICRAIADAIAMKLGAARV"
     gene            complement(2760..3188)
                     /locus_tag="ACFOV4_002010"
     CDS             complement(2760..3188)
                     /locus_tag="ACFOV4_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFC7619945.1"
                     /translation="MGFEKVEHLLPDTVLDIVDVIGLAATEQLVKAIGGARFKFGKGK
                     VDTERLAILVEAIGEVKTHELLQVYGGEELYVPRCGKALIQLRNHRFYQEFVKLRDID
                     KESGLMAMTKLCPKYGISSRTGYTIINEMSRPAAQQAALF"
     gene            complement(3169..3603)
                     /locus_tag="ACFOV4_002011"
     CDS             complement(3169..3603)
                     /locus_tag="ACFOV4_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp16 family protein"
                     /protein_id="HFC7619946.1"
                     /translation="MRRALIAKIKIAQKELGLDDGTYRAVLERVTGKRSCADMDVSEL
                     ESVVADMRSHGFKPKAKGNPHGKPHLRRTSSAAMLDKVEALLTVGGKHWNYAHAMARR
                     MFGKDKVEYLDDTQLHKLVAALQIAENRKTEKAGGDDGVRKS"
BASE COUNT          873 a         1077 c          783 g          953 t
ORIGIN      
        1 tcgtctgaaa atccttatcc atgcgtaccg cgtactcaat gcctgcctta tccaacagat
       61 cggaaacatg aatgacaaac ggctcttgct cgcgtgcgcg gcttaagccc aattccaaat
      121 cggcatggcg cacagccaac tgacgttcaa ctaattcacg gtaggtcatt ctttgatacc
      181 cattaaatat tttgtccgct tgtacaattt cttaacccac gaaatattta caaatgtata
      241 aacctttgct acaacttcgc cgtcatagtg cgcattttct cgtgcagccc gaaatttcgc
      301 cctggcttct tcagggttgt ccgcccaaat gctcaatgac caggacttgc cgttaaagcg
      361 gtaagaaaac gtgtactcat tcataggaga aaccttatgt attttgaaat ctataaagac
      421 gcaaaaggcg aataccgttg gcgtttgaaa gcagccaacc atgaaatcat cgctcagggc
      481 gaaggctaca ccagcaagca aaactgtcag cacgcagtcg atttgctgaa aagcactacc
      541 gccgctaccc ctgtaaaaga ggtataaaat ccgctttcac cctcagcccg cgccctacgc
      601 gggctttttt gtcagtttcc gactttgcgg gagtgattgc ccgcccagtc gcgccaagcc
      661 tgattttgat tttccaactc cgccacatag ccgccaaact cggcggcgtg ttccaacagc
      721 gtggccgtct tgccgtcttt cggcggattt gggcgtaccg gcgcgaccat caatgcggca
      781 ggcggtgtcg gcatgaccgc cttttcgaca accttaattt ccgtagccga gggcgcgctt
      841 gtagagctgc aagccgtgat ggccaaagcc gtcaatacaa ccgccgcctg catttttacg
      901 gtcttgagta aggacatttt cgatttcctt tttattttcc gttttcagac ggctgacttc
      961 cgcctgtttt ttcgccaaag ccatgccgac ggcgtgcgcc ttgacttcat attttttcgc
     1021 ttccgcgcgc gcctgttcca gctcgcgtgc atagttttga gccgacaaca gcatggcttg
     1081 cgccttgtcg cgcttcattt tctcaatgac cacctgctgc ttcgcaaacg ccgacttata
     1141 gccttgatgg tgcgacaccg ccaaacccgt gccgacaagc gcgataatgg caattggttg
     1201 ccagttattc gctagcagtt tcacgagatt cattctcgac ctcctgacgt ttgacgctga
     1261 ccaacgaacg cgccaccgca tagccgccga caatgcccaa atacaccgcc caaatctccg
     1321 ccgatgggtc gggcaacatc acaaatttaa acgtccccgc cgcgcaggcg acgtttgccc
     1381 acagcttcga gtgcgacaca ttgcctgtcg ccgggttttt aaaaatatcc aaaatacgca
     1441 ttgctattcc acacttttgg tttgcaggtg ccgtttcagc atttcctgat aattggccag
     1501 ttcgccctcc gcaaattcaa acgccgccaa gtctgcctgt tcgcttgcct cacggctttt
     1561 ggccgaccac agcccaatca tcttttcgta aaacgcaacc tgtcccatga ttaacgacga
     1621 ttcttgcgtt tgcgcgcagc ccgtttcgcg gctgccacgc ctgagtttct taaatttggg
     1681 cgtggatagg tgtgtatcgg acgaacattt ggcatctgta taagtgcgcg gtttacctgc
     1741 tcattactag gattttctcc aatcaatttt gtaagaaaat aggaagcagc ttctttcaat
     1801 ttaccaataa tattcatact cttgccgccc ccaatttcat cgcaatcgcg tccgcaatcg
     1861 cgcggcagat gccccatttg gtcgtcttaa acaaggccaa atcagtgtcg ttgctgacga
     1921 aaaaaggctc aacaatgccg ccagcctgcg cataagccag gcgcgaatga tggcccgcat
     1981 tgtcgggttt aaagccgtct tcgccgcgca gtttccagcc ggttttcttg gcaacagctt
     2041 tgctcaacac ctgacaccag cgtttgtttt taacggtact caacgcctca atgcccgtag
     2101 ctgctttacc ggccgccgag ttggtatgga actcaatcgc cacatccgag ccgcgaatca
     2161 gttttacagc ttcacgcagc ggcatattgc ctttgcctgt gccgccggcc gccgagttgg
     2221 tatggaactc aatcgccaca tccgagccgc gaatcagttt tacagcttca cgcagcggca
     2281 tattgccttt gcctgtgccg tcggttttaa cagtcaaacc gtagtcatcg cgcaaaatag
     2341 cagccacaat gttgcgcata tcctgcgcca agtccgcctc acggtcgctg ccgttgaccg
     2401 cacccgggtc ggtgttgctg tgtccagcgg ttaaggttac ggttttgccc attcatcatc
     2461 tccaaaaaat attgattgca tatagtggat taacaaaaat caggacaagg cgacgaagcc
     2521 gcagacagta cagatagtac ggaaccgatt cacttggtgc ttcagcacct tagagaatcg
     2581 ttctctttga gctaaggcga ggcaacgccg tactggtttt tgttaatcca ctataacatt
     2641 tgaaaacccc attaaaccgt ctttaaccca tcgtcccgaa cggtagatgt ttcacccctg
     2701 caaaccaaaa aaaagaccgt ctgaatacag acggccaaag cctggtcaca catcactgcc
     2761 taaaataaag ctgcctgctg tgccgcaggt cggctcattt cattgataat cgtatatccc
     2821 gttcgtgaag agatgccgta tttagggcat agcttcgtca tcgccataag cccgctctcc
     2881 ttatcaatat cgcgcaattt gacaaactcc tgataaaacc tatggtttct caactgtatt
     2941 aacgccttgc cgcaccgtgg gacatacaat tcctcgccac catatacctg caacagctca
     3001 tgtgttttca cttcgccgat ggcttcgacc aaaattgcca aacgctcggt gtccaccttg
     3061 cccttaccaa atttaaaccg cgccccgcca atcgccttga ccagctgttc cgtcgctgcc
     3121 agtccgatga catccacaat gtccaacacg gtatccggca ataaatgttc aactttttcg
     3181 aaccccatca tccccacccg ctttttccgt tttcctgttt tccgcaatct gcaacgcagc
     3241 aaccagttta tgtagctgcg tatcgtctaa atattcgacc ttatccttac caaacatccg
     3301 ccgcgccatt gcgtgtgcat agttccaatg tttgccgccg acggtcagca gggcttcgac
     3361 tttgtccaac attgccgctg atgatgtccg acgcagatgt ggtttaccgt gtgggttacc
     3421 ttttgcttta ggcttaaatc cgtgcgaccg catatcagcg acaacagact caagttcgga
     3481 aacatccata tccgcacacg accgcttgcc cgtcacgcgc tccaacaccg cgcgataggt
     3541 accgtcgtcc aagcccagct ccttttgggc aattttaatt tttgcaatca acgcccggcg
     3601 catctcaaac ccataaaaca caatatattg actaattaac gcatattata ccaataaaat
     3661 acaatatata gtattaagcc gatgtt
//
LOCUS       DAXISH010000101         3412 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.101, whole genome shotgun sequence.
ACCESSION   DAXISH010000101 DAXISH010000000
VERSION     DAXISH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3412
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.101"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(65..2239)
                     /gene="fetA"
                     /locus_tag="ACFOV4_002012"
                     /gene_synonym="frpB"
     CDS             complement(65..2239)
                     /gene="fetA"
                     /locus_tag="ACFOV4_002012"
                     /gene_synonym="frpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021438799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor FetA/FrpB"
                     /protein_id="HFC7619947.1"
                     /translation="MNAPFFRLSLLSLTLAAGFAHAAENNANVALDTVTVKGDRQGSK
                     IRTNIVTLQQKDESTATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNA
                     YSDSQILYHQGRFIVDPALVKVVSVQKGAGSASAGIGATNGAIITKTVDAQDLLKGLD
                     KNWGVRLNSGFASNEGVSYGASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNNFNGGK
                     TVPYSALDKRSYLAKIGTTFGDGDHRIVLSHMKDQHRGIRTVREEFTVGGDKERISMK
                     RQAPSYRETTQSNTNLAYTGKDLGFVEKLDANVYVLEKKRYSADDSGTGYAGNVKGPN
                     HTRITTRGMNFNFDSRLAEQTLLKYGINYRHQEIKPQAFLNSKFKISDKKPDPNNPGK
                     EIAKTDEEKAKDKIDMALVHSYKLSNPAKTDTGAYIEAIHEINGFTLTGGLRYDRFKV
                     KTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHNYASRSPRLYDALQTHGKRGIISIA
                     DGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDALANPQNRHVSAAVREAVNAGYI
                     KNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLLSANPEFGAQVGRTWTASLAY
                     RFKNPNLEIGWRGRYVQKAVGSILVSGQKDRQGKLENVVRQGFGVNDVFANWKPLGKD
                     TLNVNLSVNNVFNTFYYPHSQRWTNTLPGVGRDVRLGVNYKF"
BASE COUNT          771 a          768 c          943 g          930 t
ORIGIN      
        1 tcaaattatc agaacagatg ccgtctgaaa ggctttcaga cggcattttt tcgggatgtg
       61 cgttttagaa cttgtagttc acgcccaagc gtacatcacg tcccacgccc ggcagggtat
      121 tggtccagcg ttggctgtgc ggatagtaga acgtgttgaa cacgttgtta accgaaagat
      181 taacattgag cgtgtctttg cccagcggtt tccagttggc gaagacatcg ttcacaccga
      241 aaccttggcg tacaacgttt tccagtttgc cttggcggtc tttttgacct gacaccaata
      301 tcgaacccac ggctttttga acatagcgtc cgcgccagcc gatttccaga ttcgggtttt
      361 tgaagcggta ggcaagggag gctgtccaag tgcggccgac ttgtgcgcca aattcaggat
      421 tcgcgctcaa cagcttgtct ttgtgcgtat cgtaaaagcg cggtttgctg tggcttacgc
      481 cgactttggc agtcaggccg ccggtgcggt aggacgcgcc caattcgtaa ccgtggtttt
      541 tgatgtaacc ggcattgacg gcttcacgga cggcggcaga gacgtggcgg ttttgcggat
      601 tggcaagcgc gtctttgatg gtttgccaga agtagctgcc gttggcggca aacgtgccgt
      661 cgttgtagtt gaagccgatt tcggtattgc gcgcgcgttc ggctttcgtg ccgtcggcaa
      721 tcgagatgat gccgcgttta ccgtgggttt gcagcgcgtc atacaggcgc gggctgcggc
      781 tggcgtagtt gtggctcgcg ctgaagctcc agtgttcgtg cggctgccaa atcacaccga
      841 aactcgggtt aaggttgctg cttgaaacag ttttgccgtc atgggttttc accttgaagc
      901 ggtcgtaacg cagcccgccg gtcagggtaa agccgttaat ttcgtgaatg gcttcgatat
      961 acgcgccggt atcggttttg gctgggttag acagtttgta ggaatggaca agagccatat
     1021 ctatcttgtc tttcgctttt tcttcatcgg tcttagctat ttcttttccg ggattgtttg
     1081 ggtctggttt cttatcggag atcttaaatt tgctgttcaa aaatgcttgt ggtttgattt
     1141 cctgatggcg gtagttgata ccgtatttca acagggtttg ttcggcaagg cggctgtcga
     1201 agttgaaatt cataccccga gtagtgattc gggtatggtt agggcctttt acattgcctg
     1261 cgtagccggt gccgctgtca tcggcggaat agcgtttctt ttccaacaca taaacattgg
     1321 catccagttt ttcgacaaag cccaaatctt tgccggtgta cgccaagttg gtgttggatt
     1381 gggtggtttc gcggtaggat ggggcttggc gtttcatact tattcgctct ttatcgccgc
     1441 cgacggtaaa ttcttcacgg acggtacgga tgccccggtg ctggtctttc atatggctca
     1501 atacgatgcg gtggtcgccg tcgccgaagg ttgttccgat tttggcgagg tagctgcgtt
     1561 tgtccagtgc gctgtacggt acggttttgc cgccgttgaa attattacgg aagcctttac
     1621 ctgcttcgta atctttttca tcgttgcggt tgtaagagaa caaaccgtcg aagttgccct
     1681 cttttccgaa tacgcttgcg ccgtagctta cgccttcgtt gctggcaaag ccgctgttga
     1741 ggcgcacgcc ccagttttta tccaagcctt tgagcaggtc ttgggcatcg acggttttgg
     1801 tgatgatcgc gccgttggtc gcgccgatac cggcagaggc ggaacccgcg cctttttgta
     1861 cggaaacgac tttaaccaaa gcgggatcga caataaatct gccttggtgg taaaggattt
     1921 ggctgtcgga ataggcgttg tccaccttga tgtcgacaga gttctgaccc atgccgcgca
     1981 gcgtcaggaa ttgggacgtg ccgttgccgc cgccgaaatc gatggagggc tcttctttta
     2041 agagttcgcg catatcggtt gcggtgcttt cgtctttttg ttgaagcgta acgatgttgg
     2101 tacggatttt gctgccttgg cggtcgcctt ttacggtaac ggtatccaat gcgacattgg
     2161 cattattttc tgccgcatgg gcaaaacctg ccgccagggt aagcgagagc aggctgaggc
     2221 ggaaaaacgg ggcgttcatt tgttcgtcct tttgagtgta tgaagggaag taaatccaaa
     2281 ccgttaaggt ttggcaggat aagaaaaata ataattattt ttgtttatat taacgagagg
     2341 ggggatttgt gtaaagctga ttatcgtttt tatttgcgaa gtgttgtttt ttgttgacag
     2401 gttttgtcgg aaatgtatag tggactaaca aaaatcagga taaggcgacg aagccgcaga
     2461 cagtacagat agtacggcaa ggcgaggcaa cgctgtactg gtttttgtta gtccactata
     2521 aaaaacggcg gaaatatagt ggattaacaa atgcgggaat gacgaaaagc aacctttccg
     2581 cgtccttccc gcgaaagcgg gaatctagaa cccctaacgc ggcaggaatc tatcggaaaa
     2641 aaccgaaacc gaacgaacct agattcccgc ctgcgcggga atgacgaggc ctgcgcggga
     2701 atgacgaagc ctgcgcggga atgacgaaaa gcaacctttc cgcgtccttc ccgcgaaagc
     2761 gggaatctag gaactcaaag ctgcaagaat ttatcagaaa caactggaac tcaaaaaaac
     2821 tagattcccg cctgcgcggg aatgacgaag ggttaaagaa atgatgagaa acggcggtaa
     2881 tttatcggga ataaccgaaa acgaacggaa atcaggacaa ggcggcgaag ccgcagacag
     2941 tacggatagg acggaaccga ttcacttggt gcttgagcac cttagagaat cgttctcttt
     3001 gagctaaggc gaggcaacga cgtactggtt tttgttcatc cactataaca gcaaccctgt
     3061 cgccgtcatt cccgcgaaag cgggaatcca gtccgttcag tttcggtcat ttccgataaa
     3121 ttcctgctgc ttttcatttc tagattccca cttttgcggg aatgacggcg gaagggtttt
     3181 ggttttttcc gataaattct tgaggcattg aaattctaga ttcccgcctg cgcgggaatg
     3241 acggcggagc ggtttctgtt ttttccgata aattcctaaa acttaaaatt tcatcattcc
     3301 cgcaaggaca gaaaaccaaa aacagaaacc taaaattcgt cattcccacg aaagtgggaa
     3361 tctagaatcc cggactttca gataatcttt gaatattgct gttgttctaa gg
//
LOCUS       DAXISH010000102         3234 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.102, whole genome shotgun sequence.
ACCESSION   DAXISH010000102 DAXISH010000000
VERSION     DAXISH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3234
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.102"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(522..959)
                     /gene="rnhA"
                     /locus_tag="ACFOV4_002013"
     CDS             complement(522..959)
                     /gene="rnhA"
                     /locus_tag="ACFOV4_002013"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HFC7619948.1"
                     /translation="MNQTVYLYTDGACKGNPGAGGWGVLMRYGSHEKELFGGEAQTTN
                     NRMELTAVIEGLKSLKRHCTVIICTDSQYVKNGMENWIHGWKRNGWKTAAKQPVKNDD
                     LWKELDVLVGQHQVSWTWVKGHAGHAENERADDLANRGAAQFS"
     gene            1073..1942
                     /gene="tehB"
                     /locus_tag="ACFOV4_002014"
     CDS             1073..1942
                     /gene="tehB"
                     /locus_tag="ACFOV4_002014"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HFC7619949.1"
                     /translation="MKERIVGQSGELFCFGQMPVWKVENLPEILLSGYSSEEGEWVCL
                     NVLQGDVEVRAPDGAAEVWSAESGDCVFAPQQVFSVKPKTDDAEIRLSMYCTAADYFH
                     KKYGMSATHSAVAAAQDTVPAGRALDMGCGQGRNALFLGLKGFDVTAADHNPAALANV
                     AELAEAEGLNVRTLEYDLNAAALQGEFDYIVATVVLMFLMPQRVPDVIADMQAHTAAG
                     GYNLIVSAMDTADFPCPMPFPFKFKEGELKDYYRDWELVEYKEELGAMHAKDENGNPI
                     RFKFVTMLAKKPE"
     gene            complement(1992..2798)
                     /gene="thiD"
                     /locus_tag="ACFOV4_002015"
     CDS             complement(1992..2798)
                     /gene="thiD"
                     /locus_tag="ACFOV4_002015"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFC7619950.1"
                     /translation="MKSSFVQTLTIAGSDSGGGAGIQADLKTFQMRGVFGTCVITAVT
                     AQNTLGVSAVHLVPTETIFAQIQAIREDFDIRAYKIGMLGTAEIIECVADKLKHCDFG
                     RRVLDPVMIAKGGAPLLQDSAVAALTRLLLPDTDVLTPNLPEAEALTGVHIENRKDAE
                     RAAKILLDYGVKNVVIKGGHLNGSTSGRCTDWLFTQNETLELDSPRFPTAHTHGTGCT
                     FSACITAELAKGSDVCKAVQTAKAYITAAISNPLEIGAGHGPVNHWAYRD"
BASE COUNT          683 a          792 c          941 g          818 t
ORIGIN      
        1 tgcagcgttg gatttttaga ttcctgcttt cgcgggaatg actgggcggt cggatgccgc
       61 ctgaaactcc gtcattcctg caacttttcg tcattcccgt gaaaatggga atctagaact
      121 tcaaactttc agataatctt tgaatattgc cgttacccga cggactggat tcccgcctgc
      181 gcgggaatga cggtggagcg gtttcagttg tttctaaata aatttttgca gcgttggatt
      241 tttagattcc cgctttcgcg ggaatgacgg ggcggtcgga tgccgcctga agcccgacaa
      301 agcccccaat gccgtctgaa acctcgtcat tcctctgctg tccgcaactt ttcgtcattc
      361 ccgcaaaagc gggaatctag agcctctaaa ttttcagacg gcttttgaat attgccgttg
      421 cccgacggtt tggattcccg cctgcgcggg aatgacggtg gaggacgatg ccgtctaaag
      481 cccattagcg gtttcagacg gcatttttgc cggagcggca gtcaggaaaa ctgcgctgcg
      541 ccacggtttg ccaaatcgtc ggcgcgttcg ttttccgcgt gtcccgcgtg tcctttaacc
      601 caagtccagc tgacttggtg ctgcccaacc agaacgtcga gttctttcca caagtcgtcg
      661 tttttgacgg gctgtttggc ggcggttttc cagccgttgc gcttccaacc gtgtatccag
      721 ttttccatgc cgtttttaac gtattgcgag tcggtgcaga tgatgacggt gcagtggcgt
      781 ttgagcgatt tcagtccttc gatgacggcg gtcagctcca tgcggttgtt ggtggtttgc
      841 gcttcgccgc cgaaaagttc tttttcgtgg ctgccgtagc gcattaatac gccccagccg
      901 cccgcgccgg gattgccttt gcacgcgccg tcggtgtaaa ggtaaacggt ttggttcatt
      961 attgtgcctt tatgtggtgt ccggcgtgat tataagcggt ttgcgcgccg tgccgtctga
     1021 aagattgcag cggattgaaa taggcatata atgtgcaact ttatttttga atatgaagga
     1081 gcggatagtg ggtcaaagcg gcgagttgtt ttgtttcgga caaatgcctg tatggaaagt
     1141 ggaaaacctg ccggaaattt tgttgtcggg ctattcgtct gaggaagggg aatgggtctg
     1201 cctgaatgtg ttgcagggcg atgtcgaagt ccgtgcacca gacggggcgg cagaggtttg
     1261 gtcggcagaa agcggcgatt gcgtgtttgc gccgcagcag gtgttttctg tcaaaccgaa
     1321 aacggacgat gccgaaatcc gtttgtcgat gtattgcacg gcggcagact attttcacaa
     1381 aaaatacggg atgagtgcca cgcattctgc ggtcgcggcg gcacaggata ccgtaccggc
     1441 gggcagggcg ttggatatgg gctgcggaca gggacgcaac gcgctgttcc tcggcttgaa
     1501 ggggtttgac gtaaccgccg ccgatcacaa tccggctgct ttggcaaacg tggcggagct
     1561 ggcagaggcg gagggcttga acgtccgcac gctggaatat gatttgaacg ccgccgcctt
     1621 gcagggtgag tttgattata ttgtggcaac agtggtgctg atgttcctga tgccgcagcg
     1681 cgtgcctgac gtgattgccg atatgcaggc gcatacggcg gcgggcgggt acaacttaat
     1741 cgtatcggca atggatacgg cggatttccc ttgtccgatg ccgttccctt ttaaatttaa
     1801 agagggagag ctgaaggatt attatcggga ttgggagctg gtcgaatata aagaagaatt
     1861 gggcgcgatg cacgccaaag acgaaaacgg caatccgata cggtttaaat ttgtaaccat
     1921 gctggcgaaa aagcctgaat aatcctcaaa aatgccgtct gaacattttg tttcagacgg
     1981 catttttacg gttagtcccg atacgcccaa tgattgaccg gcccgtgtcc cgcgccgatt
     2041 tccaaagggt ttgagattgc cgccgtgatg taggccttgg cagtctgtac ggctttgcaa
     2101 acgtccgagc cttttgccaa ctcggcggta atgcaggcgg aaaacgtgca gcccgtgccg
     2161 tgcgtgtggg cggttggaaa gcgcgggctg tccaattcca gcgtttcatt ttgcgtaaac
     2221 agccaatccg tgcagcgtcc gcttgtgctg ccgttcaaat gtccgccttt gataacgaca
     2281 tttttgacac cgtaatcaag caggattttt gccgcacgtt ccgcatcttt acggttttcg
     2341 atatgcacgc cggtcagggc ttccgcctcg ggcaggttgg gggtcaatac atccgtatcg
     2401 ggaagcagca ggcgcgtcag tgccgcaacg gcggaatcct gcaacagcgg cgcaccgcct
     2461 ttggcaatca tcacggggtc gagtacgcgc ctgccgaagt cgcagtgttt cagtttgtcg
     2521 gcaacgcatt cgatgatttc cgccgtgccg agcattccta ttttgtaggc gcggatgtca
     2581 aagtcttccc tgattgcttg gatttgtgcg aagatggttt cggtcgggac gagatgaacc
     2641 gccgacacgc ccaaggtatt ttgcgcggta acggcggtga tgacgcacgt tccgaacacg
     2701 ccgcgcatct gaaacgtttt caaatccgcc tgaatgcccg caccgccgcc cgaatccgaa
     2761 ccggcgatgg taagcgtttg cacaaaagag cttttcattt gttcctcctt aatattgtgt
     2821 ccgataaaaa gggctaatgc ctgtaaaaaa gcacggcgat gccgtctgaa aaccgcagcg
     2881 cggggtttgt ggtgcattat atgccgtatt gcaggacaag gcacagggca gggcggcggg
     2941 gtgcatcgta gcaactgtat ttttgcccga cggggtgaaa aatacagttg ctacacccac
     3001 tgataatgaa aaaagagagc aatgccgtct gaaccgcgtg ttgcggcgag cataaaccgg
     3061 cacgctttat tcgtcattcc cacaaaaaca gaaacctaaa attccgtcat tcctacgaaa
     3121 gcgggaatcc agtgtgttcg gtttcagttg tttttgggtt tcgggtgatt tccaaatcat
     3181 cattcccgcg caggcgggaa tctagccctt ggggcagcgg caatatttat aaag
//
LOCUS       DAXISH010000103         3081 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.103, whole genome shotgun sequence.
ACCESSION   DAXISH010000103 DAXISH010000000
VERSION     DAXISH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3081
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.103"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..1443
                     /locus_tag="ACFOV4_002016"
     CDS             <1..1443
                     /locus_tag="ACFOV4_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminase domain-containing protein"
                     /protein_id="HFC7619951.1"
                     /translation="INGGSLKDNLGDAALGAIVSTVHGEVASKIKFNLSEDYITHKIA
                     HAIAGCAAAAANKGKCQDGAIGAAVGEIVGEALTNGKNPATLTAKEREQILAYSKLVA
                     GTVSGVVGGDVNTAANAAKVAIENNLLSQEEYALREKLIKKAKGKGLLSLDWGSLTEQ
                     EARQFIYLIEKDRYSNQLLDRYQKNPSSLNNQEKNILAYFINQTSGGNTAWAASILKT
                     PQSMGNLTIPSKDINNTLSKAYQTLSRYDSFDYKSAVAAQPALYLLNGPLGFSVKAAT
                     VAAGGYNIGQGAKAISNGEYLHGTVQVVNGTLMVAGSVSAQAAISAKPAPVTRYLSND
                     SAPALRQALTAESQRIRMKLPEEYRQIGNLAIAKIDVKGLPQRMEAFSSFQKGEHGFI
                     SLPETKIFKPISVDKYHNIASPPRGTLRNIDGEYKLLETIAQQLGNNRNVSGRIDLFT
                     ELKACQSCSNVILEFRNRYPNIQLNIFTGK"
     gene            1448..1831
                     /locus_tag="ACFOV4_002017"
     CDS             1448..1831
                     /locus_tag="ACFOV4_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619952.1"
                     /translation="MEKIKNYIEFKKLFKNITEKFVRDLDITLIEAAEYSIIEFEIYL
                     SEYPEDSTFIFTAWAIYLLENNCLNERGKDNFFIAEMKKCYQQTNLDRIKSIYSSSDY
                     HIFAKDVNKIQQTFKLNLANIMQQE"
     gene            2081..>3081
                     /locus_tag="ACFOV4_002018"
     CDS             2081..>3081
                     /locus_tag="ACFOV4_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer family protein"
                     /protein_id="HFC7619953.1"
                     /translation="MLKTPPMLAAELSGKTGVSISAPYANENSRIILSAADIAAENGK
                     IKLQSYGDQSYYAGQGELYTLERRSYKTGKWYNRKHITEVKEHKNAKPDAVNLSASQG
                     IDIKSGGSIDAYATVFDAPKGSINIEAGRKLTLYAVEELNYDKLDSHKKRKFLGITYD
                     KVHDTSTQQMQTALPSRVVAESANLQSGWDTKLQGTQFETTLGGAVIRAGVGDQARAD
                     AKIILEGIKTTIHNETVSSSKSALWQKQAGRGSNIETLQLPSFTGPVAPVLSAPGGYI
                     VDIPKGNLKTQIETLTKQPEYAYLKQLQTVKDVNWNQVQLAYDKWDYKQEGLTGAGAA
                     "
BASE COUNT         1023 a          669 c          657 g          732 t
ORIGIN      
        1 atcaacggcg gcagcctcaa agacaacttg ggcgatgccg cactgggtgc gatagtcagt
       61 accgtacacg gagaagtagc gagcaaaatc aaatttaatc tcagcgaaga ctacattacc
      121 cacaagattg cccatgccat agcgggctgt gcggcagcgg cggcgaataa gggtaagtgt
      181 caggatggtg cgatcggtgc ggctgtgggc gagatagtcg gggaggcttt gacaaacggc
      241 aaaaatcctg ccactttgac agctaaagaa cgcgaacaga ttttggcata cagcaaactg
      301 gttgccggta cggtaagcgg tgtggtcggc ggcgatgtga atacagcggc gaatgcggct
      361 aaagtcgcga ttgaaaataa cctattatct caagaagagt atgctcttag agaaaaattg
      421 atcaaaaaag ccaaagggaa aggcctatta tctttagatt ggggcagcct gaccgaacaa
      481 gaggcaaggc agtttatcta tttgattgag aaagatcgat attctaatca attgcttgac
      541 cgatatcaaa aaaatccaag tagtttaaat aatcaagaaa aaaatattct tgcatatttt
      601 attaaccaaa cctctggagg taacacagct tgggcagctt cgatactgaa aacgccccag
      661 tcaatgggta atctcactat tccttccaaa gatattaata acaccttatc gaaagcctat
      721 caaacattga gtcgttatga ttcttttgat tacaaatcag ctgttgccgc acaacctgca
      781 ctttacttat taaacggacc gcttggcttc agtgtcaaag cagctactgt ggcagcagga
      841 ggatataaca ttggacaggg agcgaaagca atctctaatg gagaatatct gcatggtaca
      901 gttcaggttg ttaatggcac attgatggtt gcaggatctg tatctgcaca ggctgcaata
      961 tcggccaagc ctgcacctgt tacccgttat ctgagcaatg acagtgctcc tgctttaaga
     1021 caagctttaa ctgctgaaag ccagagaatc cgcatgaaac tgccggaaga gtatcgacaa
     1081 atagggaatc ttgcgatagc aaaaattgat gttaaaggat taccgcaaag gatggaagca
     1141 tttagttctt tccaaaaagg ggaacatgga tttatttcgt tacctgaaac aaaaattttt
     1201 aaacctatat ctgttgataa atatcataat attgcctctc ctcctagagg aacattaaga
     1261 aatatagatg gagaatataa attacttgaa actatagcac agcaactcgg aaataatcgt
     1321 aatgtatcag gtagaattga tctatttaca gaattaaagg cctgtcaatc ttgcagcaat
     1381 gttattttag agtttagaaa tcgctatcca aatattcaat taaatatttt tacaggaaaa
     1441 tagaatcatg gaaaaaataa aaaattatat agaattcaag aaattattta aaaatataac
     1501 ggaaaaattt gtcagagatt tagatataac attaattgaa gcagctgaat attctataat
     1561 tgaattcgaa atttatttat ctgaatatcc ggaagatagt acatttattt ttacagcatg
     1621 ggcaatctat ctgttagaaa ataactgtct caatgaaaga ggaaaagata attttttcat
     1681 cgcggaaatg aaaaaatgtt atcaacaaac taatttggat agaataaaat ctatctattc
     1741 ttcgagtgac tatcatattt ttgctaagga tgtaaacaag attcaacaaa catttaaatt
     1801 aaatcttgcc aatatcatgc agcaagagta gcaactgtat ttttaacccc gtcgggcaaa
     1861 attaccaaaa acggtaaatc actaaaaata cttttatacc gccgccgcag caagctgtag
     1921 cctgcatgaa acctaaaatc catgcgtaag gtgtgtgctc cagcacgcac gcgttccatg
     1981 atttacggct caatgccgtc tgaaaagctc acaatttttc agacggcatt tgttatgcaa
     2041 gtaaatattc agattcccta tatactgccc agatgcgtgc gtgctgaaga caccccctat
     2101 gcttgctgca gaactttcgg gtaaaaccgg tgtgagcatt agcgcaccgt atgccaatga
     2161 gaacagccgc atcattttga gtgccgccga tatagccgca gaaaacggca aaatcaaact
     2221 gcaatcctac ggcgaccaat cctattacgc cggacagggc gaactctata ccttagaacg
     2281 ccgcagctac aaaaccggca aatggtacaa ccgcaaacac attaccgaag tcaaagaaca
     2341 caaaaacgcc aagcccgacg cagtaaacct cagcgcatcc caaggtatcg acatcaaatc
     2401 tggtggcagc atcgacgcct acgccaccgt attcgatgcc cccaaaggca gcattaacat
     2461 cgaagccggg cggaaattga cactctatgc cgtagaagag ctcaactacg acaaactaga
     2521 cagtcataag aaacgcaaat ttctcggcat tacttatgat aaggtacatg atacctctac
     2581 ccaacagatg caaactgcct taccaagccg tgtagtggct gaatcagcta atctgcaatc
     2641 aggttgggat accaagttac aaggtacgca gtttgaaacc acgctgggcg gcgcggtcat
     2701 ccgtgcaggc gtaggcgacc aggcacgggc cgatgccaag attatcctcg aaggcatcaa
     2761 aaccacgatc cacaacgaaa ccgtgagcag cagcaaatct gctctatggc aaaaacaggc
     2821 aggacggggc agtaacatcg aaaccttgca attgccgagt ttcaccggtc ccgttgcgcc
     2881 cgtactgtcc gcacccggcg gttacattgt cgatattccc aaaggcaatc tgaaaaccca
     2941 aatcgaaacc ctcaccaagc agcccgagta tgcttatctg aaacagcttc agacggtcaa
     3001 ggacgtgaac tggaaccaag tacagctcgc ttacgacaaa tgggactata aacaggaagg
     3061 cctaaccgga gccggagccg c
//
LOCUS       DAXISH010000104         3054 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.104, whole genome shotgun sequence.
ACCESSION   DAXISH010000104 DAXISH010000000
VERSION     DAXISH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3054
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.104"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            399..2624
                     /locus_tag="ACFOV4_002019"
     CDS             399..2624
                     /locus_tag="ACFOV4_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0030256 - type I protein secretion system
                     complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0030253 - protein secretion by the type I
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HFC7619954.1"
                     /translation="MRSAVLFIYFFLLNIFLFQPAVIHIQSNYILFMSIVSAPLPALS
                     ALIILAHYHGIAANPADIQHEFCTSAQSDLNETQWLLAAKSLGLKAKVVRQPIKRLAM
                     ATLPALVWCDDGNHFILAKTDGEGEHAQFLIQDLVTNKSAVLSFAEFSNRYSGKLILV
                     ASRASVLGSLAKFDFTWFIPAVIKYRRLFFEVLVVSVVLQLFALITPLFFQVVMDKVL
                     VHRGFSTLDVVSVALLVVSLFEIVLGGLRTYLFAHTTSRIDVELGARLFRHLLSLPLS
                     YFEHRRVGDTVARRELEQIRNFLTGQALTSVLDLAFSFIFLAVMWYYSSTLTWVVLAS
                     LPAYAFWSAFISPILRTRLNDKFARNADNQSFLVESITAVGTVKAMAVEPQMTQRWDN
                     QLAAYVASGFRVTKLAVVGQQGVQLIQKLVTVATLWIGARLVIEGKLTVGQLIAFNML
                     SGQVAAPVIRLAQLWQDFQQVGISVARLGDILNAPTENASSHLALPDIRGEITFEHVD
                     FRYKADGRLILQDLNLRIRAGEVLGIVGRSGSGKSTLTKLVQRLYVPEQGRVLVDGND
                     LALAAPAWLRRQVGVVLQENVLLNRSIRDNIALTDTGMPLERIIEAAKLAGAHEFIME
                     LPEGYGTVVGEQGAGLSGGQRQRIAIARALITNPRILIFDEATSALDYESERAIMQNM
                     QAICANRTVLIIAHRLSTVKTAHRIIAMDKGRIVEAGTQQELLAKPNGYYRYLYDLQN
                     G"
     gene            2848..>3054
                     /locus_tag="ACFOV4_002020"
     CDS             2848..>3054
                     /locus_tag="ACFOV4_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC7619955.1"
                     /translation="MSTFFQQTAQAMIAKHIDRFPLLKLDRVIDWQPIEQYLNRQKNR
                     YLRDHRGRPAYPLLSMFKAVLLGQW"
BASE COUNT          658 a          706 c          830 g          860 t
ORIGIN      
        1 atttttatct ctatgtttct gattggttta tgatattcga agcctcctta gaatttaagt
       61 agatagtttt ccttgtcact tcgcgcgttg cttgtcattg ataataagtc actttactcc
      121 tttcttgaaa aatcgtcaag aacagttatc aatctttaaa atctatttaa aacaaaaata
      181 tacagatatt tcaggctgcc tgaaacacaa aaaataacat tatccgaccg caacagagtt
      241 cggagcagcc tgcaccttaa ccctgttcct taacggtatg caggaggcac gagaggtgcg
      301 aggcatcctc atctaactcg attcctaagc cgttttacct tcctgaaacg agaacttttc
      361 catactttct ctttacaatt cccatatata tccttacaat gcgttctgct gttttattta
      421 tatatttctt tctacttaat atattccttt tccagccagc cgttatccac atccaatcta
      481 actatatttt atttatgtct atcgtatccg caccgctccc cgccctttcc gccctcatca
      541 tcctcgccca ttaccacggc attgccgcca atcctgccga tatacagcat gaattttgta
      601 cttccgcaca gagcgattta aatgaaacgc aatggctgtt agccgccaaa tctttgggat
      661 tgaaggcaaa ggtagtccgc cagcctatta aacgtttggc tatggcgact ttacccgcat
      721 tggtatggtg tgatgacggc aaccatttca ttttggccaa aacagacggt gagggtgagc
      781 atgcccaatt tttgatacag gatttggtta cgaataagtc tgcggtattg tcttttgccg
      841 aattttctaa cagatattcg ggcaaactga tattggttgc ttcccgcgct tcggtattgg
      901 gcagtttggc aaagtttgac tttacctggt ttattccggc ggtaatcaaa taccgccggt
      961 tgttttttga agtattggtg gtgtcggtgg tgttgcagct gtttgcgctg attacgcctc
     1021 tgtttttcca agtggtgatg gacaaggtgc tggtacatcg gggattctct actttggatg
     1081 tggtgtcggt ggctttgttg gtggtgtcgc tgtttgagat tgtgttgggc ggtttgcgga
     1141 cgtatctgtt tgcacatacg acttcacgta ttgatgtgga attgggcgcg cgtttgttcc
     1201 ggcatctgct ttccctgcct ttatcctatt tcgagcacag acgagtgggt gatacggtgg
     1261 ctcggcggga attggagcag attcgcaatt tcttgaccgg tcaggcgctg acttcggtgt
     1321 tggatttggc gttttcgttt atctttctgg cggtgatgtg gtattacagc tccactctga
     1381 cttgggtggt attggcttcg ttgcctgcct atgcgttttg gtcggcattt atcagtccga
     1441 tactgcggac gcgtctgaac gataagttcg cgcgcaatgc agacaaccag tcgtttttag
     1501 tagaaagcat cactgcggtg ggtacggtaa aggcgatggc ggtagagccg cagatgacgc
     1561 agcgttggga caatcagttg gcggcttatg tggcttcggg atttcgggta acgaagttgg
     1621 cggtggtcgg ccagcagggg gtgcagctga ttcagaagct ggtgacggtg gcgacgttgt
     1681 ggattggcgc acggctggta attgagggca agctgacggt ggggcagctg attgcgttta
     1741 atatgctctc gggacaggtg gcggcgcctg ttatccgttt ggcgcagttg tggcaggatt
     1801 tccagcaggt ggggatttcg gtggcgcgtt tgggggatat tctgaatgcg ccgaccgaga
     1861 atgcgtcttc gcatttggct ttgcccgata tccgggggga gattacgttc gaacatgtcg
     1921 atttccgcta taaggcggac ggcaggctga ttttgcagga tttgaacctg cggattcggg
     1981 cgggggaagt gctggggatt gtgggacgtt cggggtcggg caaatccaca ctcaccaaat
     2041 tggtgcagcg tctgtatgta ccggagcagg gacgggtgtt ggtggacggc aacgatttgg
     2101 ctttggccgc tcctgcctgg ctgcggcggc aggtcggcgt ggtcttgcag gagaatgtgc
     2161 tgctcaaccg cagcatacgc gacaatatcg cgctgacgga tacgggtatg ccgctggaac
     2221 gcattatcga agcagccaaa ctggcgggcg cacacgagtt tattatggag ctgccggaag
     2281 gctacggcac cgtggtgggc gaacaagggg ccggcttgtc gggcggacag cggcagcgta
     2341 ttgcgattgc ccgcgcgtta atcaccaatc cgcgcattct gatttttgac gaagccacca
     2401 gcgcgctgga ttatgaaagt gaacgagcga ttatgcagaa catgcaggcc atttgcgcca
     2461 accggacggt gctgattatc gcccaccgtc tgtccaccgt taaaacggca caccggatca
     2521 ttgccatgga taaaggcagg attgtggaag cgggaacaca gcaggaattg ctggcgaagc
     2581 cgaacggata ttaccgctat ctgtatgatt tacagaacgg gtagaaggcg ggggatgggc
     2641 gtgtaggctg cttttttcgt aacgttctgc gtttttagac cgtcgtttac tgggtttact
     2701 gactgaaatg aaaccaaagt gcaggctgcc ggaaagactt tttctgtctt tttaggcagc
     2761 ctgcacttct ttttcactca tctagagacc tttgcaaaat tccccaaaat cccctaaatt
     2821 cccaccaaga catttaggag atttctcatg agcaccttct tccaacaaac cgcccaagcc
     2881 atgattgcca aacacatcga ccgtttccca ctattgaagt tggaccgggt gattgattgg
     2941 cagccgatcg agcagtacct gaaccgtcaa aaaaaccgtt acctccgaga ccaccgcggc
     3001 cgtcctgcct atcccctgct gtccatgttc aaagccgtcc tgctcggaca atgg
//
LOCUS       DAXISH010000105         2989 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.105, whole genome shotgun sequence.
ACCESSION   DAXISH010000105 DAXISH010000000
VERSION     DAXISH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2989
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.105"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            111..221
                     /locus_tag="ACFOV4_002021"
                     /pseudo
     CDS             111..221
                     /locus_tag="ACFOV4_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005108432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family metal-binding protein"
     gene            291..674
                     /locus_tag="ACFOV4_002022"
     CDS             291..674
                     /locus_tag="ACFOV4_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HFC7619956.1"
                     /translation="MYCLRLRRLVLIFVNPLYIIATTVPAQQAFLDAAELMQWSIETE
                     GLGLNVISHKILGKDHAQVEFEAYFRDGQHRSAHHELSGFVNIGGQWYFIDPTVPHPA
                     MKQPCICGSGKKFKACCGKYLKPVA"
     gene            complement(893..1687)
                     /locus_tag="ACFOV4_002023"
     CDS             complement(893..1687)
                     /locus_tag="ACFOV4_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFC7619957.1"
                     /translation="MLHRLQKVVRHIAQTEIMPRFLNTPSHRKEDGSMLSEADIAAQT
                     AFAAALPLLIDCPMLGEEMSRQEQSALWEQYSGEKGLWIVDPIDGTNNFVNGLPHFAV
                     SVAFVRNGRAELGVIYNPVSGECFYAERGQGAFLNGTRLPLRLVDKKLNEAIAGVEIK
                     YLRSGKLSSRMSTLAPFGTIRSMGSSTLDWCYLACGRYDVYVHGGQKLWDYAAGALIF
                     EEAGGRLTTLEGDGFWSGEHVFKRSVVAALEPKLFERWVGWIRENQ"
     gene            1791..2516
                     /locus_tag="ACFOV4_002024"
     CDS             1791..2516
                     /locus_tag="ACFOV4_002024"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFC7619958.1"
                     /translation="MPRFYLPENLSVGQTVALPDNIVRHLNVLRVRPNENITLFDGKG
                     KAHAARLTVLEKRRAEAEILHEDTTDNESPLNITLIQSISSGDRMDFTLQKSVELGVT
                     AIQPVISERCIVRLDGERAAKRLARWQEIVISACEQSGRNTVPPVLPIIGYREALDKM
                     PSESTKLIMSINRARKLGDIRHPSGAIVFMVGPEGGWTEQEEQQAFEAGFQAVTLGKR
                     ILRTETAPLAALAAMQTLWGDFA"
BASE COUNT          774 a          905 c          689 g          621 t
ORIGIN      
        1 ggtatttggg gcgaaaacag ccgaaaacct gtgttggggt ttcggctgtc gggagggaaa
       61 ggaattttgc aaaggtctca agctatgccg gctgctgccg cccacttcat ctgcgccaaa
      121 tcctgccgcc caccgccgaa gccctcatgc gttcgcggta cagcgcgtat gtgctgcacc
      181 ttatcgacta tagtggatta acaaaaacca gtacagcgtt gcctcgcctt agctcaaaga
      241 gaacgattct ctaaggtgct gaagcaccga gtgaatcggt tccgtactat ttgtactgtc
      301 ttcggcttcg tcgccttgtc ctgatttttg ttaatccact atacatcatc gctactaccg
      361 ttccggcgca acaggcattc ctcgatgccg ccgaactgat gcaatggagt atagaaaccg
      421 aagggctggg cttgaacgtc atctcgcaca agatactcgg caaagaccac gcccaagtcg
      481 aatttgaagc ctacttccga gacggacaac accgatccgc gcatcacgaa ctgtccggct
      541 tcgtcaacat cggcggacaa tggtatttta tcgatcccac cgttccgcat cctgcgatga
      601 aacaaccctg catttgcgga tcaggcaaaa aattcaaagc ctgctgcggc aaatatctga
      661 aacctgtcgc ataaaaatgc cgtctgaacg ttcagacggc attttcaacg tgcaaaaaaa
      721 aaccattcat accaagggta agtatgaatg gtcaatacat tgcgggaaaa cgtcttactt
      781 gctgcactgc cgaaaaggga gaaacggcag cggtaatcag cggaaatgat tgtacccgaa
      841 ttaatgttaa gaaacgttaa tcgcgaaaat atattaacaa acctgttgaa acctattggt
      901 tttcccgtat ccacccgacc cagcgttcaa acagcttcgg ttcgagcgcg gcaacgaccg
      961 agcgtttgaa cacgtgttca ccactccaaa acccgtcgcc ttccaaagtc gtcagcctgc
     1021 cgcccgcctc ctcgaaaatc agcgcaccgg cggcataatc ccacagcttc tgcccgccgt
     1081 ggacataaac atcataacgc ccgcacgcca gataacacca gtccaacgta ctgctgccca
     1141 tactccgtat cgtcccgaaa ggcgcgagcg tactcatgcg gctggaaagt ttgcccgaac
     1201 gcagatattt gatttccacg cccgcaatcg cctcattgag ttttttatcc acgaggcgca
     1261 ggggcaggcg cgtcccgttt aaaaacgccc cctgcccccg ttcggcataa aaacattcgc
     1321 cgctgaccgg attgtagatt acgcccaatt cggcgcgccc gttgcggaca aacgccaccg
     1381 acacggcaaa atgcggcagc ccgttgacaa aattgtttgt cccgtctatc ggatcgacaa
     1441 tccacagccc cttttccccc gaatattgtt cccacaaagc cgactgttcc tgccgcgaca
     1501 tttcctcgcc caacatcggg caatcgatca gaagcggcaa cgcggcggca aaagccgtct
     1561 gcgcggcaat gtccgcctcg ctcaacatcg aaccatcttc cttgcggtga gacggcgtat
     1621 tcaaaaaacg cggcataatt tcggtttgcg cgatatggcg cacgactttc tgcaaacggt
     1681 gtaacacttc ctactgtcct catattttga acttgcggcg cgcgaacgta taatgcccgt
     1741 ttccatcacg ccgctgcgac ggattataac cgtccgaacc gccaaaaact atgccccgat
     1801 tctacctgcc tgaaaacctt tccgtcggac aaaccgtcgc cctgcccgac aacatcgtcc
     1861 gccacctcaa cgtcctgcgc gtccgcccca acgaaaacat caccctcttc gacggcaaag
     1921 gcaaggcaca cgccgcacgg ctgaccgttt tggaaaaacg ccgcgccgaa gccgaaatcc
     1981 tgcacgaaga cacaaccgac aacgagtccc cgctcaacat cacactgata caatccatct
     2041 cctccggcga tcgcatggat ttcaccctgc aaaaaagcgt cgaactcggc gtaaccgcca
     2101 tacagcccgt catcagcgaa cgctgcatcg tccgcctcga cggagaacgc gccgccaaac
     2161 gcctcgcacg ctggcaggaa atcgtcatct ccgcgtgcga acaaagcggc agaaacaccg
     2221 ttccccccgt actgcccatc atcggctacc gtgaagcact cgacaaaatg ccgtctgaaa
     2281 gcaccaagct gattatgagc atcaaccgcg cccgcaaact cggcgacatc cgccacccgt
     2341 ccggcgcaat cgtctttatg gtcgggcccg aaggcggctg gacagaacag gaagaacaac
     2401 aggcatttga agctggcttt caggcggtta cactcggcaa acggatttta cgcacagaaa
     2461 ccgccccact cgccgccctc gccgccatgc agacgctttg gggcgatttc gcataaacag
     2521 aaatgccgtc tgaaacccgt tcagacggca ttttgcagcc gattaagata gtaggttcaa
     2581 ataagatttc ccgtgtcgtc attcccgcga aagcgggaat ctagaaacga aaaactacag
     2641 ggatttatcc gaaacaacaa ccctctccgc cgtcattccc gcgcaggcgg gaatctagaa
     2701 acgaaaaact acagggattt atccgaaaca acaaaccctc tccgccgtca ttcccgcgca
     2761 ggcgggaatc tagaaattta acgttgcggt gatttatcgg aaatgactga aactcaacgg
     2821 actggattcc cactttcgcg ggaatgacga agtggaagtt acccgaaact taaaacaagc
     2881 gaaaccgaac ggactagatt cccgcctgcg cgggaatgac gaattttagg ttgctgtttt
     2941 ttggttttct gtttttgcgg gaatgacgag attttaggtt tctgttttt
//
LOCUS       DAXISH010000106         2610 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.106, whole genome shotgun sequence.
ACCESSION   DAXISH010000106 DAXISH010000000
VERSION     DAXISH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.106"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(286..939)
                     /locus_tag="ACFOV4_002025"
     CDS             complement(286..939)
                     /locus_tag="ACFOV4_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC7619959.1"
                     /translation="MKTTHCKLKKKVQKELLRFFVLEVTARSAADILGIQPDSAILFY
                     RTIRMVISHYPALAADEVFEGSVELDESYFGGRRKGRRGRGAAGKVVVFGILKRNGRV
                     YTVVVDNARSETLLPVIKRKIMPDSIVYTDSLSSYDKLHVSGFIHHRINHSKEFADRQ
                     NHINGIENFWNQAKRALRKYNEIDRKSFPLFLKECKFRFNFGTPSRQLKILRDWCGI"
     gene            1276..1710
                     /locus_tag="ACFOV4_002026"
     CDS             1276..1710
                     /locus_tag="ACFOV4_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619960.1"
                     /translation="MDNKKEFINNLTNRYMWIYPLVLNILFLPFYQPYQSFFIALGCL
                     FALVRKMQSLDFKLQNHIVLLNIKSAWADKKVFLIRIVVSWLAVMEIWMCFISESSTW
                     VCGAFCLNSEILEKIFRGFGYSGSLYFLFILMIDLNKLRESI"
     gene            1751..>2610
                     /locus_tag="ACFOV4_002027"
     CDS             1751..>2610
                     /locus_tag="ACFOV4_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HFC7619961.1"
                     /translation="MIGSGDTKQCKKFSADEFAKTIQSNFQSGIKYDGPTLATAGVSN
                     IIDEYLKDAYGGNGLKEAQRNLVAKEIADRIEAELHRQRANYQAQEAAKYSPAHGGVE
                     KSMYKHHADLQKTNTNIANRYSASANEYAAQAKSLGSLPKSVGYAALKNLGNALAALQ
                     MGEALYSNKANNIAKTGSSILGGMLAVAAAGAIASLAGVTLPFWASIAVGASIGLGIS
                     AAWDAFGVGEKLGLDPNVPAFDPFFGWLYDKTGGWEGGIPDWAKEWLGLNRDGKYHQY
                     DPLTLDLDGDG"
BASE COUNT          807 a          447 c          569 g          787 t
ORIGIN      
        1 gtacaaatat aatcctctta tacaatttat tgcacagttg attatgtctt atggagcaag
       61 cgtagggtgg gcacttgctg ccccacgcgt ttcatatttc aaggcagcct gaaactgtgt
      121 gggcataatg cctaccctac atcccaaaaa aacaagcgca gcctgcgtgt gtagggtgcg
      181 aactttcggc aggcagacac gcggttttat agtttcaagc tgagttggga tgcttaagat
      241 aaagtacaaa accttaaaaa ataagggggc tgtactagat tagccctaaa ttccacacca
      301 atcccgcaaa atttttagct gtcgggacgg tgtgccgaag ttaaaccgaa atttgcattc
      361 tttcaagaac agcgggaaag atttacgatc aatttcgttg tatttgcgca aggcgcgttt
      421 cgcctgattc caaaagtttt caatgccgtt aatgtggttc tgacggtctg caaactcctt
      481 agaatggttg atgcggtgat ggataaaacc gcttacgtgc agcttgtcat agctgctcag
      541 actatcggta taaacaatac tgtccggcat gattttcctt ttgatgacag ggagtaacgt
      601 ttcagacctg gcattatcta caacaacggt atagacccgt ccgttgcgtt tcagaatgcc
      661 gaagacaacc acttttcctg ccgcaccgcg accgcgtctg cctttacgcc gtccgccgaa
      721 atagctttcg tccaactcga cagagccctc aaaaacctca tcggcagcca aggccggata
      781 atggctgatg accatacgga ttgtgcggta gaacagaata gcggagtcgg gctggatgcc
      841 caaaatatcg gcagctgaac gggcggtaac ttcaagtaca aaaaagcgga gcagttcttt
      901 ctgtactttt ttctttaatt tgcagtgtgt tgtcttcata tttcgagggt aacatatctg
      961 ctaatctagt acagcctcaa acaaaaaaga gaaattttaa tttcgctaaa tcacataaag
     1021 attaatcaag agtatcatta aatgatatga gtgagcatct ataatgccaa gaagagttgt
     1081 taagacataa tgattattga aatagattgt aaaatagata cttagatagt ctgaaaaacg
     1141 gatttgtgaa actttttatt acgcgccatc atttgaaaat gaaacttaaa aaacacttat
     1201 cataataaat attttcttta cgttgtttgc taataaactc agtgcaatat catcgcaata
     1261 ttttatggaa attttatgga taacaaaaaa gaatttatta ataatttaac aaataggtat
     1321 atgtggatct atccattggt cttaaatatt ctatttctac ctttttacca gccctaccaa
     1381 tcttttttta ttgcgcttgg ttgtttgttt gcactggtta gaaaaatgca aagcttagat
     1441 tttaaattac aaaatcatat tgtattgtta aatataaaaa gtgcttgggc agataaaaaa
     1501 gtatttttga ttaggatagt agtgtcatgg ttggcggtaa tggaaatatg gatgtgtttt
     1561 atttcggaat catcaacgtg ggtatgcggt gctttttgtt taaatagtga aatattggaa
     1621 aaaatttttc gtggctttgg ttattctggt agtttatatt ttttatttat attgatgatt
     1681 gatctcaata agttaagaga gagtatttga atttcatttt ttgtttgact taaactcaag
     1741 gagaataaca atgattggta gtggtgatac taaacaatgc aaaaaatttt ctgcggatga
     1801 gtttgcaaaa acaatccaaa gcaactttca atcaggtatt aaatatgatg ggccgacttt
     1861 ggcaacggca ggcgtatcta atataataga tgaatactta aaggatgctt atggcggaaa
     1921 tgggttaaaa gaagcgcaac gcaatcttgt agctaaagag attgcggata gaatagaggc
     1981 agagttgcat aggcagcgtg ctaattatca agcacaagaa gctgcaaaat attctcctgc
     2041 gcatggcgga gtggagaaaa gtatgtacaa gcatcatgct gatcttcaaa aaacaaatac
     2101 taatattgct aatcgttatt ctgcaagtgc taatgaatat gcggctcaag caaaatcatt
     2161 aggaagtttg ccaaaatcag ttggctatgc tgcactaaaa aatttgggaa atgctttggc
     2221 ggcgttgcaa atgggagaag ctctatactc aaataaagct aataatatag ccaaaacagg
     2281 ctcttctatt ttaggtggta tgttagcggt tgcagcagca ggtgctatag ctagtttagc
     2341 aggagttaca ttgccttttt gggcttctat tgcagttggt gcatctattg gtttaggtat
     2401 tagtgcagca tgggatgctt ttggtgttgg ggaaaaatta ggattagacc ctaatgtgcc
     2461 agcttttgat ccattcttcg gttggctata cgataaaaca ggcggctggg aaggaggtat
     2521 tcctgattgg gctaaagaat ggttgggatt aaaccgcgat ggcaaatacc accaatacga
     2581 cccactaacc ctagacttag acggagacgg
//
LOCUS       DAXISH010000107         2609 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.107, whole genome shotgun sequence.
ACCESSION   DAXISH010000107 DAXISH010000000
VERSION     DAXISH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2609
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.107"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            77..487
                     /locus_tag="ACFOV4_002028"
     CDS             77..487
                     /locus_tag="ACFOV4_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF596 domain-containing protein"
                     /protein_id="HFC7619962.1"
                     /translation="MRKLNNHDVHKRYQDRLEEDVEFTINYELPLSCLWSTIKDFSSD
                     FEEKTEAFFILFKELLRRGHLKLQRDGQIIGHTPEEWEQIFREVWSEYEIEPNPLPGY
                     APFDIGMWLTVEAPAYAVWIDPEDGSELKYQCLE"
     gene            590..1210
                     /locus_tag="ACFOV4_002029"
     CDS             590..1210
                     /locus_tag="ACFOV4_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619963.1"
                     /translation="MLGVVPGIGESIQAYKVAKAAKNLQGMKKALDKAVTVATAQGYV
                     SKTKIKVGQTELRVTAATDKQLLKTISEGRDTTGKMTEQLFDSLAKQNGFKVLSGGKY
                     GANNGFDHVWQAADGSVVLIVESKQIRNGTVQLNPNGAGGYTQMSEDWIKQVANNLPD
                     GSPAKAAVFKAEREGKLKTAIAGVDRQTGKAVILPVKVPSKTNIRR"
     gene            1213..2148
                     /locus_tag="ACFOV4_002030"
     CDS             1213..2148
                     /locus_tag="ACFOV4_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 49 family protein"
                     /protein_id="HFC7619964.1"
                     /translation="MGHNMMTTQKWYEHITNVIMGNTANFNSGCPEAIDYVDERKGVP
                     LAAMRHILMYTEAAASHAYLFEHDLNKFKQYAYVAGKLGILRSVNSTDPEPFFFPCDM
                     LNIQDPMFLMLMSDSPQLREFLVRNIDNIANDTEAFVNRYDLNRHMIYNTLLMVEGKQ
                     LERLKQRSEKVLAHPTPSKWLQKRLYDYHFFLAFAEQDAEAMKAALEPLFDKKTARMA
                     AKETLSYFDFYLQPQIVTYAKIASMHGFDLGIDQEIAPRDLIVYDPLSAAEYQDIFDF
                     MKQYDLSYPYEYLQDWIDYYTFKTDKLVFGNAKRE"
     gene            complement(2494..>2609)
                     /locus_tag="ACFOV4_002031"
     CDS             complement(2494..>2609)
                     /locus_tag="ACFOV4_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC7619965.1"
                     /translation="ARAAYFGLLKVSAQSHLKAMCLNLLKAANKLSAPAAA"
BASE COUNT          784 a          562 c          594 g          669 t
ORIGIN      
        1 atggggatac cctgaaaatc tttgcgctga ttctaattaa gtaagcaaga ataggttata
       61 gggaaataaa attcaaatga gaaaattgaa taatcacgat gttcataaac ggtatcaaga
      121 tcgtttagaa gaggatgtag agttcactat caactatgag cttcctttga gttgtttgtg
      181 gtcaaccatc aaagactttt ccagcgattt tgaggaaaaa actgaagcgt tctttattct
      241 tttcaaagag ctgctgcgca gaggtcatct gaaactgcaa cgcgacgggc aaattatcgg
      301 gcatacgccc gaagaatggg aacaaatatt tagggaagta tggtctgaat atgaaatcga
      361 acccaatcca cttcccggct atgccccgtt tgatattgga atgtggctta cggtcgaggc
      421 tcctgcctac gccgtatgga tagatcccga agacggtagc gaattaaaat accaatgttt
      481 ggaataaatc ccgtctgaaa aacagctttt tcagacagga tttattccaa acattggtga
      541 tatacagagt tttgtacaag cacagaccgc tgccgattac ctgtttgctt tgctgggtgt
      601 ggttccgggt atcggcgaat cgatacaggc ctataaagta gcgaaagcgg caaaaaattt
      661 acaaggcatg aaaaaagcct tggacaaggc agtaaccgtt gccactgcac agggctatgt
      721 cagtaaaacc aaaatcaaag tcggtcaaac tgaattaagg gttactgcag caactgacaa
      781 acaattgctg aaaaccatta gcgaaggaag ggacacgaca ggtaaaatga ctgagcagtt
      841 atttgactct ttagctaaac aaaatggctt caaagtgctt tcgggcggca aatacggcgc
      901 aaataacggg tttgatcatg tatggcaggc tgccgatggt agtgttgttt tgattgtaga
      961 aagtaagcag attaggaacg gtacggtaca gctgaatccg aatggtgcgg gtggatatac
     1021 tcagatgagt gaggattgga ttaaacaagt tgcaaataac ttacctgatg gtagtcctgc
     1081 taaagctgct gtcttcaaag cggagcggga aggcaaatta aaaacagcaa tagcaggcgt
     1141 tgatcgtcaa acaggtaagg ccgttattct tcctgtcaaa gttccttcta aaaccaatat
     1201 aaggagataa caatggggca caatatgatg accacccaaa aatggtatga gcatattact
     1261 aatgtaatca tgggcaatac tgctaatttt aatagcggtt gccctgaagc tatagattat
     1321 gtagatgaaa gaaaaggcgt tccacttgca gcaatgagac atattttaat gtacactgaa
     1381 gctgcggctt cccatgccta tctatttgaa catgatctta ataaattcaa gcaatatgct
     1441 tatgttgcag gaaagctggg tattttgcgg agtgtaaatt ctacagaccc tgaacccttc
     1501 ttctttccct gtgacatgct caacattcaa gatccgatgt ttctgatgct gatgagcgac
     1561 agcccgcagc tgcgtgagtt tctggtgcgc aatatcgaca acatcgccaa cgatacagaa
     1621 gccttcgtaa accgctacga cctcaaccgg catatgattt acaatactct gctgatggtg
     1681 gaaggcaagc agcttgaacg tttgaaacaa cgtagcgaga aagtcttggc gcaccccacc
     1741 cctagcaaat ggctgcaaaa gcggttgtac gattaccact tcttcctcgc tttcgccgaa
     1801 caggatgccg aggcgatgaa agccgcctta gagccgcttt tcgataaaaa aaccgcgcgt
     1861 atggctgcca aagaaacatt gtcctatttc gatttctacc tgcagccgca aatcgttacc
     1921 tatgccaaaa tcgcatccat gcacggtttc gatttgggca tagatcaaga aatcgcaccg
     1981 agggatttga ttgtttacga tccgctgtcg gcagccgaat atcaagacat cttcgatttt
     2041 atgaaacagt atgacttgtc ttacccgtat gaatatctgc aggattggat agattactat
     2101 acgttcaaaa ccgataagct ggtatttggt aacgcgaagc gagagtgagc cgtaaaactc
     2161 tgagctcctg ttttatagat tacaacttta ggccgtctta aagctgaaag attttcgaaa
     2221 gctataaatt gaagcccttc cacagtacat agatctgtgt tgtggcgggg ctttaccacg
     2281 ctgattgccg gagaagaact caacctgctg gcaaaacaag gcatgagatc tttgcaataa
     2341 catgagttga gacctttgca aaaaagccct tccccgacag ccgaaaccca aacacaggtt
     2401 ttcgtctatt ttcgccccaa ataccgccta attctaccca aatatcccct taatcctgcc
     2461 cggatacccg ataatcaggc atccggtctc cttttaggcg gcagcgggcg cacttagctt
     2521 gttggcggct ttcaacaggt tcaaacacat cgccttcaga tggctttgcg cactcacttt
     2581 gagcagacca aaataggctg cccgcgcat
//
LOCUS       DAXISH010000108         2317 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.108, whole genome shotgun sequence.
ACCESSION   DAXISH010000108 DAXISH010000000
VERSION     DAXISH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2317
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.108"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(53..1462)
                     /gene="dacB"
                     /locus_tag="ACFOV4_002032"
     CDS             complement(53..1462)
                     /gene="dacB"
                     /locus_tag="ACFOV4_002032"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="HFC7619966.1"
                     /translation="MNFPKTAASLLLLLASLAAHALDTGRIPQNEIAVYVQELDSGKV
                     IIDHRSDVPVNPASTMKLVTAFAAFKTFGSNYRWATEFKSNGTVNDGTLDGNLYWAGS
                     GDPVFNQENLLAVQRQLREQGIRNITGHLMLDHSLWGEVGSPDDFEADSGSPFMTPPN
                     PTMLSAGMVMVRAERNAADSTDILTDPPLPHIFAQNNLKITASQAACPSIKKLMRASF
                     SDNTLKLRGNIPESCLGKPVGVRMFALDELIRQSFTNHWLLGGGRISDGIGISDTPEG
                     AQTLAVAHSKPMKEILTDMNKRSDNLIARSVFLKLGGDGKLPAVSEQAASAVRRELAV
                     SGIDIADLVLENGSGLSRKERVTARMMAQMLETAYFSPFAQDFIDTLPIAGTDGTLRN
                     RFKQSGGLLRLKTGTLNNVRALAGYWLGDKPMAVVVIINSGRAVSLLPDLDNFVANNI
                     ISGGDGWLDAKLMCKERRA"
     gene            1627..2193
                     /locus_tag="ACFOV4_002033"
     CDS             1627..2193
                     /locus_tag="ACFOV4_002033"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFC7619967.1"
                     /translation="MAKKISILVGSLRRASFARKVALNAAEMFPEGWQAEIVEIGHLP
                     LYNFDYDDPAVEDVPLPESYTAFRETIKASDGILFVTSENNRTIPACLKNAVDIGSKP
                     NADVAWKNKPAGIISHSVGKMGGYSSQKNLRLALSYFDMPVTGQPEVFLGNSPTLFDE
                     NGKLIDSARDFVQSYINQFVGLIERNAK"
BASE COUNT          526 a          563 c          670 g          558 t
ORIGIN      
        1 tcctagttat ctaggacagc cccttaaatt taatccacta tattttcctg tttcaggctc
       61 ggcgttcttt gcacatcagt ttcgcatcca gccagccatc gccgccggag atgatgttgt
      121 tggcaacgaa gttgtccaag tcgggcagca gggaaacggc gcggccgctg ttgatgatga
      181 cgaccaccgc catcggtttg tcgcccagcc aataacctgc aagggcgcgg acattgttga
      241 gcgtgccggt ttttaagcgc aacagcccgc cgctttgttt gaagcggttg cgtaaagtcc
      301 cgtctgtgcc ggcgatgggt agcgtatcga tgaaatcttg tgcaaacggg ctgaaataag
      361 ccgtttccaa catttgcgcc atcattctcg ccgttaccct ttcttttctg gacaggcctg
      421 aaccgttttc caaaaccaaa tccgcaatat cgatgcccga cacggcaagt tcgcgccgga
      481 cggcagatgc cgcctgttcg gaaacggcgg gcagtttgcc gtcgccgccg agtttgagga
      541 agacggaacg cgcaattaga ttgtccgaac gcttgttcat gtccgtcaaa atttccttca
      601 tcggctttga gtgtgcaacg gcaagcgtct gcgcgccttc cggcgtgtcg gatatgccga
      661 tgccgtctga aatccgtccg ccgccgagca gccagtggtt ggtaaaactt tgccggatca
      721 gttcgtcaag cgcgaacatc cggacaccga caggcttgcc caaacagctc tcgggaatat
      781 tgccgcgcaa tttcagcgta ttgtccgaaa aagatgcacg catcagtttt ttgatcgaag
      841 ggcaggcagc ttgggaggcg gtaattttca agttgttttg ggcgaaaata tgcggcaaag
      901 gcggatcggt gaggatgtcg gtactgtcgg cggcattgcg ttcggcgcgc accataacca
      961 taccggcaga cagcatagtt ggattggggg gcgtcataaa cggcgaaccg ctgtcggctt
     1021 cgaaatcgtc ggggctgccg acttcgcccc acaggctgtg gtcgagcatc aggtgtcccg
     1081 tgatattgcg tatgccttgt tcgcgcaact ggcgttggac ggcaagcagg ttttcctgat
     1141 tgaaaacggg gtcgccgctg cccgcccaat acaggtttcc gtcaagcgtg ccgtcgttta
     1201 ccgtaccgtt gcttttaaac tcggtcgccc agcggtaatt gctgccgaag gttttgaagg
     1261 cggcaaacgc ggtaacgagt ttcattgtgg aggcggggtt gacggggaca tccgagcggt
     1321 ggtcaatgat gacttttccg ctgtcaagct cttggacata tacggcgatt tcgttttgcg
     1381 gaatgcggcc ggtatcgagc gcgtgtgcgg cgagggaggc gagaagcagc agcagggagg
     1441 ccgctgtttt ggggaaattc ataggtaaat ctgttacata aaaaaagcaa ttataaggca
     1501 aagccggata agtgggaacg ctgtggcggc gggccggctt gtttgcaggg gaaatcacat
     1561 atataataat cgctatcatt atgaaatgat tgagacgcac aaacttaata ttcaggagga
     1621 atgattatgg ctaagaaaat cagtattttg gtgggcagcc tgcgccgtgc ttcttttgcg
     1681 cgcaaagtgg cattgaatgc ggcggagatg ttccccgaag gctggcaggc ggaaatcgtc
     1741 gaaatcggac atctgccgct ttacaatttc gattatgacg accctgcggt ggaagatgtg
     1801 ccgctgcccg aaagctacac ggctttccgc gaaacgatta aggcttcgga cggcattttg
     1861 ttcgttacgt ccgaaaataa ccgcaccatt cccgcctgtt tgaaaaatgc ggtggacatc
     1921 ggctcgaaac cgaatgccga cgtggcgtgg aaaaacaaac cggccggtat catcagccat
     1981 tccgtcggca agatgggcgg ttacagttcg caaaaaaacc tgcgccttgc gctgtcttat
     2041 ttcgatatgc ccgtaaccgg acagccggaa gtgtttttgg gcaattcgcc gacgctgttt
     2101 gatgaaaacg gcaaattgat cgactcggca agggattttg ttcagtcata tattaatcag
     2161 tttgttggtt tgattgaaag aaatgccaaa taaacaaacc aagtcgaaag gccgcaaaac
     2221 cggttcgggt tttgcggctt ttttatatgg gctgggcagc gtcaaggttt gccgtttgcc
     2281 ggataatgcg cggcaaatga ccggcgtgtt tatagcg
//
LOCUS       DAXISH010000109         2274 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.109, whole genome shotgun sequence.
ACCESSION   DAXISH010000109 DAXISH010000000
VERSION     DAXISH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2274
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.109"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..1889
                     /locus_tag="ACFOV4_002034"
     CDS             <1..1889
                     /locus_tag="ACFOV4_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
                     /protein_id="HFC7619968.1"
                     /translation="LNVQKSTRFIGIKVGKSNYSKNELNETKLPVRVIAQTAKTRSGW
                     DTVLEGTEFKTTLFGADIQAGVGEKARADAKIILKGIVNRIQTEEKLESNSTVWQKQA
                     GSGSTVETLKLPSFEGPALPKLTAPGGYIADIPKGNLKTEIEKLAKQPEYAYLKQLQT
                     VKDVNWNQVQLAYDKWDYKQEGLTGAGAAIIALAVAAVTGGVGAGLIGAAQGTTSAAI
                     ANAAFTSLATQASISLVNNKGNVGKTLKELGRSRTVKNLVVAAATAGVSNKIGTSALA
                     NVSDKQWVNNMTVNLADAGSAALINTAVNGGSLKDNLEANILAALVNTAHGEAASKIK
                     GLDQHYVAHKIAHAIAGCAAAAANKGKCQDGAIGAAVGEILGETLLDGRDPGSLNVKD
                     RAKIIAKAKLAAGAVAALSKGDVSTAANAAAVAVENNSLNDIQDRLLSGNYALCMSAG
                     GAESFCESYRPLGLPHFVSVSGEMKLPNKFGNRMVNGKLIINTRNGNVYFSVGKIWST
                     VKSTKSNISGVSVGWVLNVSPNDYLKEASMNDFRNSNQNKAYAEMISQTLVGESVGGS
                     LCLTRACFSVSSTISKSKSPFKDSKIIGEIGLGSGVAAGVEKTIYIGNIKDIDKFISA
                     NIKK"
     gene            1939..>2274
                     /locus_tag="ACFOV4_002035"
     CDS             1939..>2274
                     /locus_tag="ACFOV4_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619969.1"
                     /translation="MSWVLVILIIGTFYDYYQIRQYAELEKKSISNILLYAQKEKFRL
                     ESKDKYMRGGYTKYEFIFSEYSNTTFLNFINDLKKDNYLPLDGYGHGFLCRKGESISI
                     NIYPEINKFI"
BASE COUNT          736 a          447 c          554 g          537 t
ORIGIN      
        1 aattgaatgt tcagaaaagt acccgtttca tcggcatcaa agtgggtaaa agcaattaca
       61 gcaaaaacga gctgaacgaa accaaactgc ccgtacgcgt tatcgcccaa acagccaaaa
      121 cccgttccgg ctgggatacc gtactcgaag gcaccgaatt caaaaccacc cttttcggag
      181 ccgacataca ggcaggggtg ggtgaaaaag cccgagccga tgcgaaaatt atcctaaaag
      241 gcatcgttaa ccgcatccaa accgaagaaa agctggaatc caactcgacc gtatggcaaa
      301 agcaggccgg aagcggcagc acggttgaaa cgctgaagct accgagcttt gaagggccgg
      361 cactgcctaa gctgaccgct cccggcggct atatcgccga catccccaaa ggcaacctca
      421 aaaccgaaat cgaaaagctg gccaaacagc ccgaatatgc ctatctgaaa cagcttcaga
      481 cggtcaagga cgtgaactgg aaccaagtac agctcgctta cgacaaatgg gactataaac
      541 aggaaggcct aaccggagcc ggagccgcaa ttatcgccct ggcagtagcg gcggtaaccg
      601 gaggagtagg cgcaggcctt atcggagcgg cacagggaac cacatctgcc gccatagcca
      661 atgcagcatt tacctcgctg gctacccaag cttccatttc gctggttaat aacaaaggca
      721 acgtcggcaa aaccctgaaa gaactgggca gaagccgtac ggtgaaaaat ctggtcgtgg
      781 ctgctgccac cgcaggcgta tccaacaaaa tcggcacgtc tgctttagcc aatgtcagcg
      841 acaagcagtg ggtcaacaac atgaccgtga atctggccga tgcgggcagt gccgcgctga
      901 ttaacaccgc cgttaacggc ggtagcctga aagacaattt ggaagcgaat atccttgcgg
      961 ctttggtgaa taccgcgcat ggggaggcgg cgagtaagat caaaggactg gatcagcact
     1021 atgtcgccca caaaatcgct catgccatag cgggctgtgc ggctgcagcg gcgaataagg
     1081 gcaagtgtca ggatggtgcg atcggcgctg cggtcggtga aatccttggc gaaaccctac
     1141 tggacggcag agaccctggc agcctgaatg tgaaggacag ggcaaaaatc attgctaagg
     1201 cgaagctggc agcaggggcg gttgcggcgt tgagtaaggg ggatgtgagt acggcggcga
     1261 atgcggctgc tgtggcggta gagaataatt ctttaaatga tatacaggat cgtttgttga
     1321 gtggaaatta tgctttatgt atgagtgcag gaggagcaga aagcttttgt gagtcttatc
     1381 gaccactggg cttgccacac tttgtaagtg tttcaggaga aatgaaatta cctaataaat
     1441 tcgggaatcg tatggttaat ggaaaattaa ttattaacac tagaaatggc aatgtatatt
     1501 tctctgtagg taaaatatgg agtactgtaa aatcaacaaa atcaaatata agtggggtat
     1561 ctgtcggttg ggttttaaat gtttccccta atgattattt aaaagaagca tctatgaatg
     1621 atttcagaaa tagtaatcaa aataaagcct atgcagaaat gatttcccag actttggtag
     1681 gtgagagtgt tggtggtagt ctttgtctga caagagcctg cttttcggta agttcaacaa
     1741 tatctaaatc taaatctcct tttaaagatt caaaaattat tggggaaatc ggtttgggaa
     1801 gtggtgttgc tgcaggagta gaaaaaacaa tatacatagg taacataaaa gatattgata
     1861 aatttattag tgcaaacata aaaaaatagg agttagtatg aaatatatga ttaattttct
     1921 aaaaaaacat ttgaattaat gagttgggta ttagtcatac taataattgg gacattttat
     1981 gactattatc aaataaggca atatgctgaa ttagaaaaga aatctatatc aaatatcttg
     2041 ctatatgccc aaaaagaaaa atttcgctta gagagtaaag ataaatacat gcgaggagga
     2101 tatacaaaat atgaatttat tttttcagaa tatagtaata ctactttttt aaacttcata
     2161 aatgacctga aaaaagataa ttatttacca cttgacggct atggacatgg ttttctatgt
     2221 agaaaaggag agtctatatc aatcaatata taccctgaaa ttaataaatt tatt
//
LOCUS       DAXISH010000110         2146 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.110, whole genome shotgun sequence.
ACCESSION   DAXISH010000110 DAXISH010000000
VERSION     DAXISH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2146
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.110"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..>2146
                     /gene="frpC"
                     /locus_tag="ACFOV4_002036"
     CDS             <1..>2146
                     /gene="frpC"
                     /locus_tag="ACFOV4_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated protein FrpC"
                     /protein_id="HFC7619970.1"
                     /translation="GFAGALFDHRNQGIRTATGWVAADDGLLVRDLNGNGIIDNGAEL
                     FGDNTKLADGSFAKHGYAALAELDSNGDNIINAADAAFQSLRVWQDLNQDGISQANEL
                     RTLEELGIQSLDLAYKDVNKNLGNGNTLAQQGSYTKTDGTTAKMGDLLLAADNLHSRF
                     KDKVELTAEQAKAANLAGIGRLRDLREAAALSGDLANMLKAYSAAETKEAQLALLDNL
                     IHKWAETDSEWGKKPPMHLSTSWTQTANGGVALTPSQVTRLKQNALVSLSDKAKAAID
                     AARDRIAVLDAYTGQDSSTLYYMSEEDALNIVKVTNDTYDHLAKNIYQNLLFQTRLQP
                     YLNQISFKMENDTFTLDFSGLVQAFNHVKETNPQKAFVDLAEMLAYGELRSWYEGRRL
                     MADYVEEAKKAGKFEDYQKVLGQETVALLAKTSGTQADDILQNVGFGHNKNVSLYGND
                     GNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYDYATGRKDIIRFTDGITADML
                     TFTREGNHLLIKAKDGSGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLDVATVKKLVQQ
                     STDGSDRLYAYQSGNTLNGGLGDDYLYGADGNDLLNGDAGNDSIYSGNGNDTLNGGEG
                     NDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQD
                     TVYNYDYATGRKDIIRFTDGITADMLTFTREGN"
BASE COUNT          609 a          507 c          532 g          498 t
ORIGIN      
        1 ggctttgcag gtgcattgtt cgaccaccgc aatcaaggca tccgcaccgc caccggttgg
       61 gttgctgccg atgacggttt actcgtccgc gatttgaacg gcaacggcat catcgacaac
      121 ggcgcggaac tcttcggcga caacaccaaa ctggcagacg gttcttttgc caaacacggc
      181 tatgcagctt tggccgaatt ggattcaaac ggcgacaaca tcatcaacgc ggcagacgcc
      241 gcattccaat ccctgcgtgt atggcaggat ctcaaccagg acggcatttc ccaagctaat
      301 gaattgcgta cccttgaaga attgggtatc caatctttgg atctcgccta taaagatgta
      361 aataaaaatc tcggcaatgg taacactttg gctcagcaag gcagctatac caaaacagac
      421 ggtacaaccg caaaaatggg ggatttactt ttagcagccg acaatctgca cagccgcttc
      481 aaagacaaag tggaactcac tgccgaacag gcaaaagccg ccaatcttgc gggcattggt
      541 cgtctgcgcg atttgcgcga agctgccgca ttgtccggtg atttggccaa tatgctgaaa
      601 gcttattctg ccgccgaaac taaagaagca cagttggcat tgttagataa tttgattcac
      661 aaatgggcgg aaaccgattc ggaatggggc aaaaaaccgc cgatgcatct ttcaaccagt
      721 tggacgcaaa cggctaacgg gggtgtggct cttaccccgt ctcaagtaac gcgactaaaa
      781 cagaacgctt tagtttctct ttccgacaaa gccaaagcag ctatcgatgc cgcccgcgac
      841 cgcattgccg tgcttgatgc ctacacgggg caggattcca gcacactcta ttacatgagc
      901 gaagaagacg cgcttaatat cgtcaaagta accaacgata catacgacca tctcgccaaa
      961 aacatctacc aaaacctgtt attccaaacc cgtttgcagc catatttgaa tcaaatcagt
     1021 ttcaaaatgg aaaatgatac gttcactttg gattttagtg gtcttgttca agcatttaac
     1081 catgtcaaag aaactaatcc gcaaaaagct tttgtggatt tggccgagat gcttgcatat
     1141 ggcgaacttc gttcttggta tgaaggccga agactaatgg ccgattatgt ggaggaggca
     1201 aaaaaagcag gtaaatttga agattaccag aaagtgttgg gtcaggagac cgttgcatta
     1261 ttagctaaaa catcgggtac gcaagcagat gatatcctgc aaaatgtagg ctttggtcat
     1321 aataaaaatg tttctttata tggtaatgac ggcaacgaca ctctaatcgg cggtgcaggt
     1381 aatgattact tggagggcgg cagcggttcg gatacttatg tcttcggcaa aggcttcggt
     1441 caggatacgg tctataatta cgactacgct accggacgca aagacatcat ccgctttacc
     1501 gacggtatta cagccgatat gctgactttt acccgagagg gcaaccatct tcttatcaag
     1561 gcaaaagacg gcagtggaca agtgactgtt cagtcctatt tccagaacga tggctcaggt
     1621 gcttaccgta tcgatgagat tcatttcgat aacggcaaag tactggatgt tgccactgtc
     1681 aaaaaactgg tacagcaatc caccgacggt tcggacagat tgtatgccta ccaatccgga
     1741 aataccttaa atggcggatt gggcgatgac tatctgtacg gtgccgacgg gaatgacctg
     1801 ctgaatggtg atgcaggcaa cgacagtatc tacagtggca atggcaatga tacgctcaat
     1861 ggaggagaag gcaacgacgc cctgtacggc tataatggta acgatgcact gaatggtggc
     1921 gaaggcaatg atcatttgaa cggcgaagac ggtaacgaca ctctaatcgg cggtgcaggc
     1981 aatgattact tggagggcgg cagcggttcg gatacttatg tcttcggcaa aggcttcggt
     2041 caggatacgg tctataatta cgactacgct accggacgca aagacatcat ccgctttacc
     2101 gacggtatta cagccgatat gctgactttt acccgagagg gcaacc
//
LOCUS       DAXISH010000111         1855 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.111, whole genome shotgun sequence.
ACCESSION   DAXISH010000111 DAXISH010000000
VERSION     DAXISH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.111"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            501..1661
                     /locus_tag="ACFOV4_002037"
     CDS             501..1661
                     /locus_tag="ACFOV4_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HFC7619971.1"
                     /translation="MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNIQLQLTEPL
                     QNIQQPQVTKRKSRIRTKISDFGSFIGFKGSEDLGEGLKAVWQLEQDVSVAGGGATRW
                     GNRESFVGLAGEFGTLRAGRVANQFDDASKAIDPWDSNNVVASQLGIFKRHDDMPVSV
                     RYDSPEFSGFSGSVQFVPAQNSKSAYTPAHFVQQTPQSQPTLVPAVVGKPGSDVYYAG
                     LNYKNGGFAGNYAFKYAKHANVGRDAFELFLLGSGSDEAKGTDPLKNHQVHRLTGGYE
                     EGGLNLALAAQLDLSENADKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKG
                     ENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF"
BASE COUNT          466 a          444 c          477 g          468 t
ORIGIN      
        1 agattcccgc ctacgcggga atgacggctg cagatgcccg acggtcttta tagcggatta
       61 acaaaaatca ggacaaggcg gcgaagccga agacagtaca aatagcacgg aaccgattca
      121 cttggtgctt cagcacctta gagaatcgtt ctctttgagc taaggcgagg caacgccgta
      181 ctggtttttg ttcatccact ataaagtgcc gtgtgtgttt tttatggcgt tttaaaaagc
      241 cgggactgca tccgggcagc agcgcatcgg cccgcacgag gtctgcgctt gaattgtgtt
      301 gtagaaacac aacgtttttt gaaaaataag ctattgtttt atatcaaaat ataatcattt
      361 ttaaaataaa ggttgcggca tttatcagat atttgttctg aaaaatggtt ttttgcgggg
      421 ggggggggta taattgatga catatcgggt gtttgcccga tgtttttagg tttttatcaa
      481 atttacaaaa ggaagccgat atgcgaaaaa aacttaccgc gctcgtattg tccgcactgc
      541 cgcttgcggc cgttgccgat gttagcctgt acggcgaaat caaagccggc gtggaaggca
      601 ggaacatcca gctgcagttg accgaaccgc tccaaaatat tcaacaacct caggttacta
      661 agcgcaaaag ccgcatcagg acgaaaatca gcgatttcgg ctcgtttatc ggctttaagg
      721 ggagcgagga tttgggcgaa gggctgaagg ctgtttggca gcttgagcaa gacgtatccg
      781 ttgccggcgg cggcgcgacc cgttggggca acagggaatc ctttgtcggc ttggcaggtg
      841 aattcggcac gctgcgcgcc ggccgcgttg cgaatcagtt tgacgatgcc agcaaagcca
      901 ttgatccttg ggacagcaat aatgttgtgg cttcgcaatt gggtattttc aaacgccacg
      961 acgatatgcc ggtttccgta cgctacgatt cccccgaatt ttccggtttc agcggcagcg
     1021 tccaattcgt tccggctcaa aacagcaagt ccgcctatac gccggctcat tttgttcagc
     1081 agactcctca aagtcagcct actctcgttc cggctgttgt cggcaagccg gggtcggatg
     1141 tgtattatgc cggtctgaat tacaaaaatg gcggttttgc cgggaactat gcctttaaat
     1201 acgcgaaaca cgccaatgtg ggccgtgatg cttttgagtt gttcttgctc ggcagcggga
     1261 gtgatgaagc caaaggtacc gatcccttga aaaaccatca ggtacaccgc ctgacgggcg
     1321 gctatgagga aggcggcttg aatctcgcct tggcggctca gttggatttg tctgaaaatg
     1381 ccgacaaaac caaaaacagt acgaccgaaa ttgccgccac tgcttcctac cgcttcggta
     1441 atgcagttcc acgcatcagc tatgcccatg gtttcgactt tatcgaacgc ggtaaaaaag
     1501 gcgaaaatac cagctacgat caaatcatcg ccggcgttga ttatgatttt tccaaacgca
     1561 cttccgccat cgtgtctggc gcttggctga aacgcaatac cggcatcggc aactacactc
     1621 aaattaatgc cgcctccgtc ggtttgcgcc acaaattcta aatatcgggg cggtgaagcg
     1681 gatagctttg tttttgacgg ctcgccttca ttctttgatt gcaatctgac tgccaatctg
     1741 cttcagcccc aaacaaaaat ccggatacgg aagaaaaacg gcaataaaga cagcaaatac
     1801 cgtctgaaag attttcagac ggtatttcgc attttcggct tggtttgcac atata
//
LOCUS       DAXISH010000112         1795 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.112, whole genome shotgun sequence.
ACCESSION   DAXISH010000112 DAXISH010000000
VERSION     DAXISH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1795
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.112"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            278..1696
                     /locus_tag="ACFOV4_002038"
     CDS             278..1696
                     /locus_tag="ACFOV4_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HFC7619972.1"
                     /translation="MNIHTLLSKQWTLPPFLPKRLLLSLLILLAPNAMFWVLALLTAT
                     ARPIVNLDYLPAALLIALPWRFVKITGVLAFWLAVLFDGLMMVIQLFPFMDLIGAINL
                     VPFILTAPAPYQIMTGLLLLYMLAMPFVLQKAAAKTDFRHIAVCAAVVAAAGYFTGHL
                     SYYDRGRMANIFGANNFYYAKSQAMLYTVSQNADFITAGLVDPVFLPLGNQQRAATHL
                     NEPKSQKILFIVAESWGLPANPELQNATFAKLLAQKDRFSVWESGSFPFIGATVEGEM
                     RELCAYGGLRGFALRRAPDEKFARCLPNRLKQEGYATFAMHGAGSSLYDRFSWYPRAG
                     FQEIKTAENLISKKTCAIFSGVCDSELFGEVSAFFKKHDKGLFYWMTLTSHADYPESD
                     IFNHRLKCIEYGLPAETDLCRNFSLHTQFFDQLADLIQRPEMKGTEVIIVGDHPPPVG
                     NLNETFRYLKQGHVAWLHFKIK"
BASE COUNT          396 a          572 c          421 g          406 t
ORIGIN      
        1 cctgttttcc tttccccgac acgcgcgcgc gacccctgcc gcaccgtgcc gcactttcgc
       61 gcccggacgg catcgttccg ccatccggtt ctctgtttca aatacccctg tttcagaaag
      121 aaattccaga tgcttcaaca cacaggacga catataaagc accgccctat gtgttgccct
      181 gatttggaag gggttgcgcc tcccaaataa agtctgatcc tgccgccccg aaggacagat
      241 gtccgagtgg cgaagtttca accgaaaagg aaatacgatg aatattcaca ccctgctctc
      301 caaacaatgg acgctgccgc cattcctgcc aaaacggctg ctgctgtccc tgctgatact
      361 gctggccccc aatgcgatgt tttgggtttt ggcactgctg accgccactg cccgcccaat
      421 tgtcaatttg gactaccttc ccgccgcgct gctgatcgcc ctgccttggc gtttcgtcaa
      481 aattaccggc gtattggcgt tttggctggc ggttttgttt gacgggctga tgatggtgat
      541 ccagcttttc ccttttatgg acctcatcgg cgccatcaac ctcgtcccct tcatcctgac
      601 cgcccccgcc ccttatcaga taatgaccgg gctgttgctg ctgtatatgc tggcgatgcc
      661 gtttgtgttg cagaaagccg ccgccaaaac cgacttccgg cacattgccg tctgcgccgc
      721 cgttgtggcg gcagccggct atttcaccgg ccatttgagt tactacgacc ggggtcggat
      781 ggccaatatc ttcggcgcaa acaacttcta ctacgccaaa agtcaggcga tgctctacac
      841 cgtcagccag aatgccgact ttattaccgc cggcctggtc gaccccgtct tcctcccctt
      901 gggcaatcag cagcgtgccg ccacgcatct gaacgagccg aaatctcaaa aaatcctctt
      961 tatcgtcgcc gaatcttggg ggctgccggc caatcccgaa cttcaaaacg ccacttttgc
     1021 caaactgctg gcgcaaaaag accgtttttc agtttgggaa agcggcagtt ttccctttat
     1081 cggcgcgacg gtcgaaggcg aaatgcgcga attgtgcgcc tacggcggtt tgcgcgggtt
     1141 tgcactgcgc cgcgcgcccg acgaaaaatt tgcccgctgc ctccccaacc gtttgaaaca
     1201 agaaggttac gccacctttg cgatgcacgg cgcgggcagt tcgctttacg accgcttcag
     1261 ctggtatccg agggcgggct ttcaagaaat caaaaccgcc gaaaacctga tcagtaaaaa
     1321 aacctgcgcc attttcagcg gcgtgtgcga cagcgagctg ttcggcgaag tgtcggcatt
     1381 tttcaaaaaa cacgacaagg gactgtttta ctggatgacg ctgaccagcc acgccgacta
     1441 tcccgaatcc gacattttca accacaggct caaatgcatc gaatacggcc tgcctgccga
     1501 aaccgacctc tgccgcaatt tcagcctgca cacccaattc ttcgaccaac tggcagattt
     1561 aatccaacgc cccgaaatga aaggcacgga agtcatcatc gtcggcgacc atccgccgcc
     1621 cgtcggcaac ctcaatgaaa ccttccgcta tctcaaacag gggcacgtcg cctggctgca
     1681 cttcaaaatc aaataacaac aatgccgtct gaacgcacca acagccttca gacggcattt
     1741 tgcagacaga ccgacccctc aagcccactt tttcatcatt tccgataaat tgctt
//
LOCUS       DAXISH010000113         1735 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.113, whole genome shotgun sequence.
ACCESSION   DAXISH010000113 DAXISH010000000
VERSION     DAXISH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1735
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.113"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            357..1661
                     /locus_tag="ACFOV4_002039"
     CDS             357..1661
                     /locus_tag="ACFOV4_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFC7619973.1"
                     /translation="MKKHIWAASLLPASLSAEPLNWWKPYSAVNSGDTAWVMTAAALV
                     LLMTLPGLALFYGGMVRKKNLLSTMMHSFSIATLVGILWVAVGYSLAFTPGNAFIGGL
                     GRVFLSGMQIDATAQMLTVSPNAPTVPEPVFMFFQMTFAIISTAIITGAFAERMKYSA
                     MMLFSGIWFLLVYVPGAHWVWGGGFMSKGGVLDYAGGTVVHINAGIAGLVAALVLGRR
                     IGYGREAMPPHNMAMTLIGAAMLWFGWFGFNAGSALAADAAAGMAMAVTQVSAVFGAA
                     GWLACEKIAGHKPSALGLASGAVSGLVGITPAAGFTGPSGAAAIGILTAAACFVSVTV
                     VKHKLRYDDSLDAFGIHGFGGLVGGILTGIFFDNRIFGGDAAVWQQLWIQVKDGFVMA
                     AYSGLMSWAILKVVGKICGGLRVGKDVEREGLDLNIHGERVE"
BASE COUNT          359 a          432 c          509 g          435 t
ORIGIN      
        1 caattaaaaa tttttaatat attaatcaat aaattaattt tataaaataa aaatattgtc
       61 aacaatattt tgccttatcg cccaaacctc tgtatatttt cctacagtaa attgttgaca
      121 atccatacgc ccacatatgc gccgcctaag gataaatcct cccgccggac aacgggtgca
      181 agggattgga tgcgatattt ccatattcaa acaagggatt tgtttcacgc acagggcggc
      241 acatcggcaa aatccccgcg ccgccccggt ccagcagggc ttgcgtccct cccggacaag
      301 ccccgacccc gcctttccga aagacgggct caaccattaa ggaaacttta atcaaaatga
      361 aaaaacacat atgggcggca tctttgctgc cggcatccct atcggcagaa cctttaaact
      421 ggtggaagcc ttattccgcc gtcaattcgg gcgataccgc ctgggtgatg actgcggctg
      481 ccttggtact gttgatgacg cttcccgggc tggctttatt ctacggcggt atggtgcgga
      541 aaaaaaacct gctctcgacg atgatgcaca gcttttccat cgcgacattg gtgggcatcc
      601 tttgggtcgc cgtcggctat tctttagcgt tcacgccggg aaatgccttt atcggcggtt
      661 tggggcgtgt atttttaagc gggatgcaga tagacgctac cgcacagatg ctgaccgtgt
      721 cgcccaatgc gccgactgtt cccgaaccgg tatttatgtt ttttcagatg acgtttgcca
      781 ttatttcgac cgccattatt accggcgcgt ttgccgaacg gatgaaatat tcggcaatga
      841 tgctgttttc gggcatatgg tttttattgg tttatgtgcc gggcgcgcat tgggtgtggg
      901 gcggcggctt tatgagcaag ggcggcgtat tggattatgc cggcggtacg gtggtgcaca
      961 tcaatgccgg tatcgcggga ctcgtcgccg ccttggtttt gggcaggcgc ataggctacg
     1021 ggcgcgaggc gatgcctccg cacaatatgg cgatgacact gatcggcgcg gcaatgttgt
     1081 ggttcggctg gttcggcttt aacgccggat cggcgcttgc ggcagacgcg gcggcgggta
     1141 tggcgatggc ggtaacgcag gtgtcggccg tattcggcgc ggcaggctgg cttgcctgcg
     1201 aaaaaatagc gggacacaaa ccttccgctt tggggctggc ttccggcgcg gtttccggtc
     1261 tggtcggcat cacccctgcc gccggcttta ccggcccgtc tggagcggcc gccatcggta
     1321 tattgactgc cgccgcgtgc tttgtgtccg tcaccgtcgt caaacacaaa ttgcgttacg
     1381 atgattcttt ggacgctttc ggcatacacg gattcggcgg gctggtgggc ggaatattga
     1441 ccggcatctt tttcgacaac cgcattttcg gcggggatgc ggcagtttgg cagcagttgt
     1501 ggatacaggt aaaagacggg ttcgttatgg cggcatacag cgggctgatg agttgggcga
     1561 ttttgaaggt cgtggggaaa atctgcggcg gcctgcgcgt cggcaaggat gtcgaacgcg
     1621 aaggtttgga tctgaatatc cacggagaac gcgtggaata agggcggcta tgccgtctga
     1681 agcctgaaaa tcgggtttca gacggcattt ttcacgtttg ccgccgatgg ataaa
//
LOCUS       DAXISH010000114         1717 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.114, whole genome shotgun sequence.
ACCESSION   DAXISH010000114 DAXISH010000000
VERSION     DAXISH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1717
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.114"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..433)
                     /locus_tag="ACFOV4_002040"
     CDS             complement(<1..433)
                     /locus_tag="ACFOV4_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619974.1"
                     /translation="MQPGSKNDEKNKITLNEFNNAIVTIFSDENVVRAIGTINTMHGE
                     YLTRSHKIDQQKFLSDGERLSSKAKDFQHSAEKTQRALKEGIGRAASKFHANSKEAFV
                     ARKMQSDLQKKLNASNYNKQQYARQAVTALENASKAENKGNI"
     gene            complement(483..989)
                     /locus_tag="ACFOV4_002041"
     CDS             complement(483..989)
                     /locus_tag="ACFOV4_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619975.1"
                     /translation="MDFFDFFAQGKYKKIATEQGLDRKYFIFHYIVCNLSAISSFCLM
                     KVVHSYTILCLLIMIIGIAFGFILRNRVLSIVKNKQKFLSDMFPLEMPFFSRVYKIPI
                     LARFLNRGMKWLYLQNFFCLVMICFSISLILNEERGWMPYFICYWFGLCYPANTYYVF
                     LSRDYKRI"
BASE COUNT          595 a          318 c          241 g          563 t
ORIGIN      
        1 caatattacc tttattttct gcttttgaag cattttccaa agctgtgact gcttgtcttg
       61 catattgttg cttgttatag ttactagcat ttaacttctt ttgcaaatca ctttgcattt
      121 ttcttgcaac aaatgcctcc ttcgaattgg catgaaattt actagcagcc cttccaatcc
      181 cttcttttaa agccctttga gttttttctg ctgagtgctg aaaatctttc gctttactag
      241 acaaccgctc accatcactc aaaaattttt gttgatctat tttatgcgaa cgagttaaat
      301 actccccatg cattgtgtta attgtaccga ttgccctaac cacattttca tcagagaaaa
      361 tagttacaat ggcattattg aattcattta gtgtaatctt atttttttca tcattcttag
      421 aaccgggttg catgacaaca ccttccatca actaaaatat tatattatta agagactaca
      481 acttagatac gtttataatc tctggataaa aaaacgtaat aagtgtttgc tggataacaa
      541 agtccaaacc aatagcagat aaaataaggc atccaccccc tttcttcatt aaggataaga
      601 gatatcgaga aacaaatcat aactaaacag aaaaaatttt ggagataaag ccatttcatt
      661 cccctattca agaatctggc caagataggt attttgtata ctctagaaaa gaaaggcatt
      721 tccaagggaa acatatcaga taaaaacttt tgtttatttt ttactataga tagaacccta
      781 tttctcaaga taaatccaaa tgcaatgcca attatcatta ttaataaaca aaggatagta
      841 taactatgga caaccttcat taaacaaaaa gaagaaatgg cagataaatt acatacgata
      901 tagtggaata taaaatattt acggtctaaa ccttgttcag ttgcaatttt tttatactta
      961 ccttgcgcaa aaaaatcaaa gaaatccatt aaactatctt tcacattaga aatttaaaag
     1021 ctaaataata cgacaaacaa tgtgaagtac tattcatggt ttatttaaaa aataatacta
     1081 ttctgaacat tatttagata cagaaattaa caaattggaa ctaaacaagc ttttaaatac
     1141 tttaatttta ttggaaagct ataaaaggaa ctatagtttc acacactaat tacttcctaa
     1201 tcacttcttt attaagaggc acaagggatt gggaaggctg tcttggagat aagcactgat
     1261 gttctaggca aacccctcca tcttaaagtt aaaacaacca caggcagcct ggaaatgatc
     1321 tatgatctat gcccatacaa ggacattcta gatagttttc cttgttgctt cgtgtatcac
     1381 acaagataga attggcactc tactctttcc ttaaaaaacc gtcaagaatg gttatcaatt
     1441 tttttaaact tattcaaaac aatattctta tacacatctc aaacccgctg aaataaagca
     1501 aagtggtggt tcatagatgg caataccgat ttcaaagcag cctgcacttt gacaacacac
     1561 gagaaatacg ggaagaacag ggcatcagca tatatttcag cccgaagccg tttcattcgt
     1621 ttaaaaaact gcttttttca caatttacct ttacaaagcc tatacgtatc cttacaattt
     1681 gttttgctgt ttttggtata tttttggggc tgtacta
//
LOCUS       DAXISH010000115         1601 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.115, whole genome shotgun sequence.
ACCESSION   DAXISH010000115 DAXISH010000000
VERSION     DAXISH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1601
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.115"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            46..738
                     /locus_tag="ACFOV4_002042"
     CDS             46..738
                     /locus_tag="ACFOV4_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="opacity family porin"
                     /protein_id="HFC7619976.1"
                     /translation="MQADLAYAAERITHDYPQATGANNTSTVSDYFRNIRAHSIHPRV
                     SVGYDFGGWRIAADYASYRKWNDNKYSVNTKEVLRNNTSGNWKELKTENQENGTFHAV
                     SSLGLSAIYDFKLNDKFDKFKPYIGARVAYGHVKHQVHSVRKETTTAFLAPTGNAKVP
                     GKIVQGPVSQPAYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFK
                     THEVSLGVRYRF"
BASE COUNT          429 a          464 c          383 g          325 t
ORIGIN      
        1 gcagcgcagg cggcaagtga agacagcagc cgcagcccgt attatgtgca ggcggattta
       61 gcttatgccg ccgaacgcat tacccacgat tatccgcaag caaccggtgc aaacaacaca
      121 agcacagtaa gcgattattt cagaaacatc cgtgcgcatt ccatccaccc tcgtgtgtcg
      181 gtcggctacg acttcggcgg ctggagaata gcggcagatt atgccagtta cagaaaatgg
      241 aacgacaata aatattccgt caacacaaaa gaggtgctaa gaaacaatac cagtggcaac
      301 tggaaagaac tgaagacgga aaatcaggaa aacggtacgt tccacgccgt ctcttctctc
      361 ggcttatcag ccatttacga tttcaaactc aacgataaat tcgataaatt caaaccctat
      421 atcggcgcgc gcgtcgccta cggacacgtt aaacatcagg ttcattcggt gagaaaagaa
      481 accacgactg ctttccttgc accaacggga aacgctaaag tgccaggcaa gatcgtacaa
      541 ggtccagtca gccaacctgc ctatcacgaa agccacagca tcagcagctt gggtcttggt
      601 gtcatcgccg gtgtcggttt cgacatcacg cccaagctga ccttggacac cggataccgt
      661 taccacaact ggggacgctt ggaaaacacc cgattcaaaa cccacgaagt ctcattgggc
      721 gtgcgctacc gcttctgatt ccccgatacc gatgccgtct gaaccttcag acggcatttt
      781 tgatgcacct gccgtttaca gacgcggggc gggcgtggaa ataccccaac cgtcattccc
      841 gacaacaccg taatctcgaa attcgtcatt cccgcgcagg cgggaatcca gacccccgac
      901 gcggcgggaa tctatcggaa atgactgaaa ccccgagatt ctagattccc acttccgtgg
      961 gaatgacggt tcagttgcgt tccgacaaca ccgtaatctc gaaacccgtc cgacaacacc
     1021 gtaatcttga aattcgtcat tcccgcacag gcgggaatcc agaccccctg acgcggcggg
     1081 aatctatcgg aaatgactga aaccccgaga ttctagattc ccacttccgt gggaatgacg
     1141 tggtgcaggt ttccgtatgg atggattcgt cattcccgac aacaccccaa tcttgaaacc
     1201 cgtcattccc gcacaggcgg gaatctagac ctgtccgcac agaaacttat cggataaaaa
     1261 cagttgctca aacccctcgt tctagattcc cactttcgtg ggaatgacgt ggtgcaggtt
     1321 tccgtatgga tgggcgcagg cgggaatcca gacctctgac gcggcgggaa tctatcggaa
     1381 atgactgaaa ccccgagatt ctagattccc acttccgtgg gaatgacggt tcagttgcgc
     1441 tccgacaaca ccgtaatctt gaaacccgtc cgacaacacc gtaatcttaa aacccgtcat
     1501 tcccgcgcag gcgggaatcc agccccccga cgcggcggga atctatcgga aatgactgaa
     1561 accccgagat tctagattcc cacttccgtg ggaatgacgt g
//
LOCUS       DAXISH010000116         1474 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.116, whole genome shotgun sequence.
ACCESSION   DAXISH010000116 DAXISH010000000
VERSION     DAXISH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1474
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.116"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            184..396
                     /locus_tag="ACFOV4_002043"
     CDS             184..396
                     /locus_tag="ACFOV4_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger domain-containing protein"
                     /protein_id="HFC7619977.1"
                     /translation="MPHIHPLHLFPPHIAERGLLYFQQGKVGAVQKTSTGRYRAEVCG
                     LENYWVWLKLDSDLYIKDESCDCPYV"
     gene            580..848
                     /locus_tag="ACFOV4_002044"
                     /pseudo
     CDS             580..848
                     /locus_tag="ACFOV4_002044"
                     /inference="COORDINATES: protein motif:HMM:NF017953.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase"
     gene            complement(938..1387)
                     /locus_tag="ACFOV4_002045"
     CDS             complement(938..1387)
                     /locus_tag="ACFOV4_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin protein"
                     /protein_id="HFC7619978.1"
                     /translation="MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRA
                     ALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEGFCIRLNGIARGALDSKFMLKAV
                     AIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK"
BASE COUNT          472 a          355 c          222 g          425 t
ORIGIN      
        1 ttttgcaaag gtctcagtct ttttaaacca cagcccttcc caactaaacc aaaaggtcgt
       61 ctgaacccta ttttcagacg accttttgcc actttgtaaa acaaatcttc ccaccatcct
      121 ctccccaaac atcgcccgaa ccagtaaact tctcatattt caacaacttc ttggaagcaa
      181 accatgcccc atatccaccc gctccacctg ttcccgcccc atatcgccga acgcggactg
      241 ctctattttc agcagggcaa agttggtgct gtccaaaaaa cttccaccgg gcgttatcgg
      301 gcggaggtat gcggtttgga aaactattgg gtatggctga agctggatag tgatttgtat
      361 attaaagacg aaagctgcga ttgcccttat gtctaaaggt gcaaacatac cttaaattac
      421 tatattacat aggcaaaata caagcctata acgaattgga aacaaaatgc cgtctgaaag
      481 cattataaaa tctgttcacc ttttcagatg agtaatgtac acccctatac aatttttgct
      541 actatacccc ataaatccac ggctaaagat atccttatta tgtcctatga tttatcgaaa
      601 cgacttgtaa tcggcttagc atcaagtgcc ctattcgact tatccgaatc ggataatata
      661 tttagaatgg aaggggcaga aacctatagg caatatcaga gagaaaaaca aaaccatccc
      721 ctaaaaaagg cgttgtcttt ccatttatta aaaaacttct gtcaatcaat gaaataaacc
      781 caaacgaccc aacgattggg tttattcttt tatccagaaa caatccagat acagattacg
      841 agtcataact ataggcttaa tattacacga ttctcattcc atcaaggcgg aaaaccgcac
      901 aaatactgaa acactatcga tcgatttgta aacaagccta cttaagtaac ttgcagtcct
      961 tatcatttcc tttaaaataa tccagcccgt cactacacga actggcggac ttcttgcaaa
     1021 taaaggttac tagattttca ttcatcttaa taataaaagg atttttatct ttatctatgg
     1081 ctaccgcctt caacatgaat ttactgtcta aggccccgcg cgcgattcca ttcaaacgga
     1141 tacaaaagcc ttctgcctct ttaatcggca aacttggcca tttggtagat gtttgtttaa
     1201 atctcccatt ctgcagataa aacttttcca taaaatgtgc attttctaac aaggctgccc
     1261 gcactgcatt tatctttgct ttctcaacat aattgcgata gctcggataa acaattaaag
     1321 caagtacaga caatatcaag accactgata ttaattcaac cagcgtaaac ccccgattat
     1381 cagtcattac tttacttcca ataagaacag attattcaac atatttcttt gaacagactt
     1441 actatcccat tcagcagtat gcatatttcc cact
//
LOCUS       DAXISH010000117         1428 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.117, whole genome shotgun sequence.
ACCESSION   DAXISH010000117 DAXISH010000000
VERSION     DAXISH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1428
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.117"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(483..914)
                     /locus_tag="ACFOV4_002046"
     CDS             complement(483..914)
                     /locus_tag="ACFOV4_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619979.1"
                     /translation="MMFFQIACNSGNSYISLLKSMRFYIDNKECDYIFFRKAVNISDD
                     FIQSGFITPEGLITKNSNPKLFNQYSKMVSKNKCQYEMVTFLSDEMKNIIELLSNDDA
                     YIEFAYSEDFYVLPEIKIDKRTLKSLNFYIDFGVKYIINKI"
     gene            complement(988..>1428)
                     /locus_tag="ACFOV4_002047"
     CDS             complement(988..>1428)
                     /locus_tag="ACFOV4_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619980.1"
                     /translation="KKQITAAVMMLSMIAPAMANGLDNQTFENQVFHTQADAPMQLAE
                     LSQKEMKETEGAAAPLVAIGILHAGRFLAQRWVTQRVAAQALSRGANVYARTSQQARA
                     VANQAWGRQNVIRHGQKEIHSNYSHFQNSSQKIRGHAFYGNKHR"
BASE COUNT          461 a          266 c          200 g          501 t
ORIGIN      
        1 tcctagttat ctaggacagc ccctaaactt tttggaagca tctctaattt attaatatcg
       61 ttcatatccc ctacacacag aaaaaatctt ggggaatttc ctttaatctt tttaataaat
      121 cttcacaaag cctaaaatga tttaatttta gtttcttttt atttttttga taaattctag
      181 ataacctcgc ttattaggaa aaatttcagg atatattcct ttttcttcta aagaagtata
      241 gtggattaaa tttaaatcag gacaaggcga ggaagccgca gacagtacaa atagtacggc
      301 aaggcgaggc aacgccgtac taatccacta tatatatcca ttcatataga gaaaaattct
      361 tatacccaat ataaaacaag gtctttcatt atattttgaa aaacctagaa gctttgtatc
      421 tattggttta tcaaaattaa taattattgc agaagacatg taggctaata atcttgattt
      481 atctatattt tattaattat atatttaacc ccgaagtcaa tatagaaatt tagtgatttt
      541 aaagttctct tatcaatttt aatctcaggg agtacataaa aatcctcaga ataggcaaac
      601 tctatatatg catcatcatt cgataataat tcaataatat ttttcatttc atccgaaaga
      661 aatgtaacca tctcatattg acatttattt ttagatacca tttttgaata ttgattaaat
      721 aattttggat tactattttt agtaattaat ccttccggag taataaaacc actttgtata
      781 aagtcatcac ttatattaac agccttccga aaaaaaatat aatcacactc tttgttatca
      841 atataaaatc tcatactctt taataatgaa atataagaat ttccagaatt acaagcaatt
      901 tgaaaaaaca tcattactcc taaaactcat aaatagtaag gaatatatat atatgcatat
      961 tccttactat tttttcacaa attatgctta tctatgctta tttccataaa aagcatgccc
     1021 tcgaattttt tgacttgagt tctggaaatg agaataattt gaatggattt ccttctgtcc
     1081 atgtctaata acattttgtc ttccccaagc ttggtttgct accgctcttg cttgttgaga
     1141 tgttcgtgca tagacattag ctcctcttga taaagcttgt gctgcaacac gctgcgtaac
     1201 ccaacgctgc gcaaggaatc tgcccgcatg caaaattcct attgccacca acggtgccgc
     1261 agccccttca gtttctttca tctccttttg agaaagctcc gccaactgca tcggcgcatc
     1321 tgcctgcgtg tggaacactt ggttttcaaa tgtctgattg tccaagccgt ttgccattgc
     1381 gggggcaatc atagacagca tcattacggc tgcggtgatt tgtttttt
//
LOCUS       DAXISH010000118         1411 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.118, whole genome shotgun sequence.
ACCESSION   DAXISH010000118 DAXISH010000000
VERSION     DAXISH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1411
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.118"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(146..409)
                     /locus_tag="ACFOV4_002048"
     CDS             complement(146..409)
                     /locus_tag="ACFOV4_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619981.1"
                     /translation="MDKEIKICPRCEQGYLYHAKPKYFSGEVILCDECYAMWLGDMKI
                     FYGQYGKDFYDYHEFMKDKGIEEINMWEGELFDHPYYEDEKFK"
     gene            complement(428..>1411)
                     /locus_tag="ACFOV4_002049"
     CDS             complement(428..>1411)
                     /locus_tag="ACFOV4_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
                     /protein_id="HFC7619982.1"
                     /translation="VNGGSLKDNLEANILAALVNTAHGEAASKIKQLDQHYIVHKIAH
                     AIAGCAAAAANKGKCQDGAIGAVVGEIVGEALVKNTDFSGMTASEIEKAKANITAYAK
                     LVAGATVGVTGGNVDVAANASETAVKNNALDIIWDIGNLVWDGGKWIYAKSIGDKQMA
                     REAAIDFGVDAAAAAVPFVPAGATKISRGGAYVLKAGDEAVDTAKAIQEIQKQTGIKL
                     TYDKVNKVWTTPAGLDYGLDAKHGNRIKHVLAHTIPNPNKPVHSVFNVSRKEVLPLVD
                     EAWRMKGNPLPNDSSVYLVDMKKPIGTKGETKVRIVVQKGTNKIISAYPQK"
BASE COUNT          373 a          357 c          238 g          443 t
ORIGIN      
        1 ttggtgttgg tgaatgcctt cggctgccag cagttgcatt gaggccgtct gaaaaacgga
       61 tattcagacg gcctattgct actttaaata atatttgggt ttaaaatatc atcgtatttc
      121 ccaaattcgg ggaacagaaa atcaattatt taaatttttc atcctcataa tatgggtgat
      181 caaaaagctc tccttcccac atatttattt cttctatgcc tttatctttc ataaactcat
      241 gataatcata aaaatctttt ccatattgtc cgtaaaaaat tttcatatcc ccaagccaca
      301 tagcataaca ttcatcgcat aaaatgacct ccccagagaa atatttaggc tttgcatgat
      361 aaaggtagcc ttgctcacat cttgggcaaa ttttaatttc tttatccata agagattcct
      421 ttcttaatta tttctgagga tatgcagaaa tgattttatt tgttcctttt tgcacaacaa
      481 tccgcacttt tgtttctcct tttgttccaa taggtttctt catatctaca agatatacgg
      541 atgaatcatt tggcaaagga tttcctttca ttctccaagc ttcatcaacc aaaggcaaaa
      601 cttctttacg ggacacatta aaaacagaat gaacaggttt gtttggattt ggaattgtat
      661 gggctaaaac atgtttaatc ctattaccat gcttagcatc taacccataa tctaaccccg
      721 ccggtgttgt ccaaacctta ttaaccttat cataagtaag cttgattccg gtctgcttct
      781 gaatttcctg tatggcttta gccgtatcaa ctgcttcgtc tcccgccttc agaacataag
      841 ccccgcctcg gctgatttta gtcgcacctg ccggaacaaa gggaacggca gctgcggcgg
      901 catccacacc aaaatcaatc gccgcttctc gagccatctg cttatcgcca atagatttgg
      961 cgtaaatcca tttaccgccg tcccatacga ggttgccgat atcccaaata atatctaatg
     1021 cattattttt aacagctgtt tcggaagcat ttgccgccac atcaacattg cctcctgtaa
     1081 cacctacagt cgctccggct accaattttg catacgcagt aatattcgct ttagcttttt
     1141 caatttcaga agcagtcata ccgctgaaat cggtattctt aaccaaagcc tccccgacaa
     1201 tctcccccac gaccgcacca atcgcgccgt cctgacactt gcccttattc gccgccgctg
     1261 ccgcacagcc cgctatggca tgggcaatct tgtggactat gtagtgctga tccaactgtt
     1321 tgattttact ggctgcttct ccatgcgcag tattcaccaa agccgcaagg atattcgctt
     1381 ccagattgtc tttcaggctg ccgccgttga c
//
LOCUS       DAXISH010000119         1369 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.119, whole genome shotgun sequence.
ACCESSION   DAXISH010000119 DAXISH010000000
VERSION     DAXISH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1369
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.119"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..797)
                     /locus_tag="ACFOV4_002050"
     CDS             complement(<1..797)
                     /locus_tag="ACFOV4_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619983.1"
                     /translation="MYSNNAITNNRNNITLGAYRDAIIFIFSDENVVRAIGTINSMYE
                     EYLTRSHKIDQKEFLREGERLSAKAREFQRTAEEAQKSLKEGIGRAASKFRGNSKEAF
                     VARKVQSDLQKALNASNYNKQQYARRAATALENASKSKVMAANLGKFTYGATVAMGTL
                     SMGSAWWKALDGEGNWSDVGLSSASFLGGLMGVQWGAALGVGAFGLLTGGAGWLVVGA
                     ILGGGAGAWWGSLGAEKAWRWFEDFLNLNRSDKYHVYDPLALDLDGDG"
BASE COUNT          471 a          301 c          167 g          430 t
ORIGIN      
        1 ccgtcgccgt ctagatctag ggcgaggggg tcgtaaacgt ggtatttgtc gctgcggtta
       61 agatttaaga aatcctcaaa ccatctccaa gctttttcag ctcctaatga tccccaccaa
      121 gctcctgcgc cacctccaag tatagctcca actactagcc aacctgcgcc accagtaagt
      181 aaaccaaaag ccccaacacc caaagccgca ccccattgga cgcccattag cccacccaaa
      241 aaagaagctg atgagagacc aacatcactc caatttcctt ctccatccaa ggctttccac
      301 caagcacttc ccatactcaa agttcccatg gcaacagttg ccccataagt aaacttaccc
      361 aaattcgctg ccataacttt tgattttgaa gcattctcta acgctgttgc cgcacgtctt
      421 gcatattgct gcttgttata gttgctagca ttcaatgctt tttgcaaatc actttgtact
      481 tttcttgcaa caaatgcctc ctttgaatta ccacgaaatt tactagcagc tcttccaatt
      541 ccttctttta agcttttttg tgcctcttct gctgtgcgtt ggaattctct tgccttagca
      601 gacagacgct caccctccct taaaaattct ttttgatcta tcttgtgcga acgggtcaaa
      661 tattcttcgt acattgagtt aatcgtacca atcgccctaa ccacattttc atcagaaaat
      721 atgaaaataa tagcatccct atacgcacct agtgtaatat tgtttctatt attagttata
      781 gcattattcg aatacataat agcacctcca aatttagaac tgaatacgtt tatattctct
      841 gtgtaataat atcaaataat taattaatgg ataagtaagt ccgaaaaaat aacaactaaa
      901 ataagcaata tactgattct ctcctttatt aattagatat attgaaaaac aaataaaaaa
      961 taaacagaaa acattcatgt gaaaaagcca cctcatattc ttatttataa gtttaaaata
     1021 actaggcatt gtatatttaa aaatcggcac atccaacgga aacaaaccac ataaaaattt
     1081 ttctttattc tttattaaag acatagtttt attttttaaa attagtccaa ataatatact
     1141 aacaattact attaaaacaa taagcacagc gtaatttttt ataaaattca ttaaaataat
     1201 aacgaaaata ctaaatagat tacatactat aaattgaaat ataaaatatt cagtatttaa
     1261 tccattttca accgcgagtt ttttaaaata tccttgctcg aaaaaattaa aaaaatccat
     1321 taatactttc ctctcaagaa aactaatttt agtttagtta agataaaat
//
LOCUS       DAXISH010000120         1297 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.120, whole genome shotgun sequence.
ACCESSION   DAXISH010000120 DAXISH010000000
VERSION     DAXISH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.120"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(241..1095)
                     /locus_tag="ACFOV4_002051"
     CDS             complement(241..1095)
                     /locus_tag="ACFOV4_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HFC7619984.1"
                     /translation="MFYQILALIIWSSSFIAAKYVYGGIDPALMVGVRLLIAALPALP
                     ACRRHVGKIPREEWKPLLIVSFVNYVLTLLLQFVGLKYTSAASASVIVGLEPLLMVFV
                     GHFFFNDKARAYHWICGAAAFAGVALLMAGGAEEGGEVGWFGCLLVLLAGAGFCAAMR
                     PTQRLIARIGAPAFTSVSIAAASLMCLPFSLALAQSYTVDWNVGMVLSLLYLGLGCGW
                     YAYWLWNKGMSRVPANVSGLLISLEPVVGVLLAVLILGEHLSPVSALGVFVVIAATLV
                     AGRLSHQK"
BASE COUNT          367 a          380 c          330 g          220 t
ORIGIN      
        1 cactataaaa tcccgtcatt cccgcgcagg cgggaatccg gacatccaac gctgcagcaa
       61 tttgtcggaa ataaccgaaa ctcaaaaaac cggatgcccg cctgcgcggg aatgacgatg
      121 caaagatggt cgttatttcg gataaatatc cgtcttttcg ttccggatac ccgctttcgc
      181 aggaatggag atggaaagat ttcagcctat tcggcaatca tcaaataccg cttcccaact
      241 ttatttttga tgcgacagcc ggccggcaac caaggtggcg gcgatgacga caaacacgcc
      301 caaggcggac acgggcgaca ggtgttcgcc caaaatcaaa accgccagca gcacgccgac
      361 gacgggttcg agcgaaatca acagtcccga aacgttggca ggaacacggc tcatcccctt
      421 gttccacagc caataggcgt accagccgca ccccaagccc aaatacagca gcgacaatac
      481 catcccgacg ttccagtcca cggtataact ttgcgccaaa gcaagcgaaa acggcaggca
      541 catcaacgat gcggcggcaa tggaaacaga tgtgaatgcc ggtgcgccga tgcgtgcaat
      601 cagcctttgc gtcggacgca tagcggcaca aaagcccgcg cccgccaaca acaccagcag
      661 gcagccgaac cagccgactt cgccgccctc ttccgcaccg cccgccatca gcagcgcgac
      721 accggcaaat gccgccgcgc cgcatatcca gtggtaggca cgcgctttgt cgttgaagaa
      781 aaagtgtccg acaaacacca tcagcagcgg ctcgagtccg acaatgaccg atgcgctggc
      841 ggcggaagtg tatttcaacc cgacaaactg aagcagcagg gtcagcacat agttgacgaa
      901 cgacacaatc agcaacggct tccattcctc acgcggaatc ttgccgacat gacggcggca
      961 ggcgggcagt gcaggcagcg cagcaatcag caggcgcacg ccgaccatca atgcgggatc
     1021 gatgccgcca tagacatatt tggcggcaat aaacgagctg ctccagataa tcagggcaag
     1081 gatttggtaa aacatagtga gtgataaagt cagatgatca tacaaaagta tagcggatta
     1141 acaaaaatca ggacaaggcg acgaagccgc agacagtaca aatagtacgg aaccgattca
     1201 cttggtgctt cagcacctta gagaatcgtt ctctttgagc taaggcgagg caacgccgta
     1261 ctggtttttg ttcatccact ataacagcaa ccctgtc
//
LOCUS       DAXISH010000121         1201 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.121, whole genome shotgun sequence.
ACCESSION   DAXISH010000121 DAXISH010000000
VERSION     DAXISH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1201
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.121"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..214)
                     /locus_tag="ACFOV4_002052"
     CDS             complement(<1..214)
                     /locus_tag="ACFOV4_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619985.1"
                     /translation="MRLSLYGCFYFTFSFVWAWFEEAGGYRFLLVVLKIVSFSADFRH
                     FFIGVGYLYWHGASGVLIGSEFEIFEF"
     gene            359..874
                     /locus_tag="ACFOV4_002053"
     CDS             359..874
                     /locus_tag="ACFOV4_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
                     /protein_id="HFC7619986.1"
                     /translation="MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAI
                     LLAEGQKSAVTEYYLNHGEWPANNSSAGVATSANIKGKYVQSVTVANGVITAQMASSN
                     VNNEIKGKKLSLWAKRQDGSVKWFCGQPVQRANANGANNDEVTAATGKGTDKIDTKHL
                     PSTCRDESTAD"
BASE COUNT          382 a          335 c          231 g          253 t
ORIGIN      
        1 caaattcaaa aatctcaaat tccgacccaa tcaacacacc cgatgcccca tgccaataga
       61 gataccccac gccaataaaa aagtgccgaa aatcggcact aaaactgaca attttcaaca
      121 ctactaacaa aaaacggtaa ccccctgctt cctcaaacca cgcccaaacg aaagaaaatg
      181 taaaataaaa acaaccatat aaagataaac gcataaattt tcacctcaaa acacaaactt
      241 gataccaatc ttgctttata atgcacaggt atcgtaacaa aataccgatg gtcaaataca
      301 ttgcataatg ccgatggcgt aagcttgaag catttccttt ccaattagga gtaattttat
      361 gaacaccctt caaaaaggtt ttacccttat cgagctgatg attgtgattg ccatcgtcgg
      421 cattttggcg gcagtcgccc ttcctgctta tcaagactac acagcccgcg cacaagtttc
      481 cgaagccatt cttttggctg aaggtcaaaa atcagccgtc accgagtatt acctgaatca
      541 cggcgaatgg cccgccaaca acagttctgc cggcgtggca acctccgcca acatcaaagg
      601 caaatatgtt caaagcgtta cagtcgcaaa cggcgtcatt accgcccaaa tggcttcaag
      661 caacgtaaac aatgaaatca aaggcaaaaa actctccctg tgggccaagc gtcaagacgg
      721 ttcggtaaaa tggttctgcg gacagccggt tcagcgcgcc aacgccaacg gcgccaacaa
      781 cgacgaagtc accgccgcca ccggcaaggg caccgacaaa atcgacacca agcacctgcc
      841 gtcaacctgc cgcgatgaat caactgccga ctaaggtaaa ttataccata aattttaaat
      901 aaatcaagcg gtaagtgatt ttccacggcc actcggatta atccgggtgg cttccttttt
      961 aaaggtttgc aaggcaagcg gggtcgtccg ttttggtgga aaataatata tcgactgcgc
     1021 ttcaaggctc tgcgcgtacc tcattgccgc ccgtttaaac acgtggttta tctgacaggc
     1081 gcgcaatccg ccctctcatt taccgaacaa gcggactaga ttcccgccta ctcgggaatg
     1141 atgaagctat ccgcacggaa acctgcacca cgtcattccc acaaggacag aaacccacaa
     1201 a
//
LOCUS       DAXISH010000122         1175 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.122, whole genome shotgun sequence.
ACCESSION   DAXISH010000122 DAXISH010000000
VERSION     DAXISH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.122"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(333..743)
                     /locus_tag="ACFOV4_002054"
     CDS             complement(333..743)
                     /locus_tag="ACFOV4_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619987.1"
                     /translation="MKIYNLDNIITSSALSLYKSTWVKLDLISCAKFIIKGTDFTFDW
                     DEGIENWIVFFHKNKVIGYLCAKLPFAILDNEQLKNQLYHKYPHVLTLQIKNIETEKI
                     SLNVNICRLTLCPSFHDEHDTLVCSVQDFYVNTV"
     gene            complement(747..>1175)
                     /locus_tag="ACFOV4_002055"
     CDS             complement(747..>1175)
                     /locus_tag="ACFOV4_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HFC7619988.1"
                     /translation="PAKQATPNGKAGVSTQQSLQNSLVPQKNYTHTTYNGGSAITDGK
                     YITDPLSMVRHKPDASSLDKIDSKSLFKSDVDAEKATLDAARYADKHNLWDSQNKAKV
                     PTNDVVGYTDGKPTHIINIYRRKPNKDGFRPVHGTPGKER"
BASE COUNT          356 a          209 c          187 g          423 t
ORIGIN      
        1 ttgtatccga caaaaatatt tgacgcgtct atcgtttccg aaatgccgct gttgaaaaac
       61 gtcggattcg agaatccgac ctacggttgc tgaacaatgt tttgtagaac ttgctcaaaa
      121 tccatgtttc gccattttcc tttatatata cctaatgcag cacgggttac gatttcgttt
      181 aagtcataaa tagccattta cgtcctctgc taattttcag cgagtagatt gggttaccaa
      241 acccaacaaa aaagcagcct gaaaaatttc aggatgcttg ttttatgttt tttatcaatg
      301 aattaggttt taatccagcc tgcgcttgct agttaaacag tatttacata aaaatcttgc
      361 actgaacaaa caagcgtatc atgttcatca tgaaatgatg ggcataacgt taatctacaa
      421 atgtttacat ttaaagatat tttttcagtt tcaatatttt taatttgtaa ggttaataca
      481 tgaggatatt tgtgatatag ctgatttttt aattgttcgt tgtctaatat agcaaaaggt
      541 aattttgcac acaaataacc aataactttg tttttatgaa aaaaaactat ccaattttca
      601 attccttcat cccaatcaaa agtaaaatcc gttcctttta tgataaattt agcacaagat
      661 attaaatcta acttaaccca agtggattta tacagactca atgctgatga agttataata
      721 ttatctaaat tataaatttt cataaatcaa cgttccttac ctggtgttcc atgcacaggt
      781 ctaaacccat ctttattcgg ctttctacga taaatgttaa ttatatgtgt cggttttccg
      841 tctgtatagc caactacgtc gttcgttgga acttttgcct tattttgact atcccataaa
      901 ttatgtttat ctgcatatct agcagcatct aatgtagctt tttccgcatc aacatctgat
      961 ttaaataaac ttttgctatc tatcttgtct agactagatg catcaggttt gtgtcgtacc
     1021 atactgagag ggtcagtaat atatttacca tctgtaatag ctgatccacc attataggta
     1081 gtatgcgtat aatttttttg tggaacgaga ctattttgca aagattgttg tgtagaaacg
     1141 ccagctttgc cattaggagt agcttgcttc gctgg
//
LOCUS       DAXISH010000123         1174 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.123, whole genome shotgun sequence.
ACCESSION   DAXISH010000123 DAXISH010000000
VERSION     DAXISH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.123"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            25..>1174
                     /locus_tag="ACFOV4_002056"
     CDS             25..>1174
                     /locus_tag="ACFOV4_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6716 putative glycosyltransferase"
                     /protein_id="HFC7619989.1"
                     /translation="MNKKRVLLIASYDSFLNTGYAVAKEINYSTIDIYIHQTKKNILS
                     ESQLSLNGLSLKEINFFHIDDYFDKLMYQNYDIVILSLGNGLLTRFFRNSSKLNLTLP
                     IVITLFPGVIFGDSESIITRLGANILLFNNYYDYQIGNKFKERYNLSCTNILYGYPIL
                     RKKHHCSDGNKVYFIDQVKIPDGKKERLLILKKLIALANRYPHKDLVLLLRVHQNDIT
                     VHEDKYSYAELAKNMKLPDNFKIERKRTQDALQEMGYCLSFSSTMLFEAESCGIPIGV
                     ISDLGVDKKYANTHFKDSGVLVNLDTVDLDSPNTINPTWAELYTNPDSLSSKEFNQLL
                     EVTSTQPPSFDNYFIAVNDVQPVSMVLLRKFKKLIYHPKQFFVDSKLYK"
BASE COUNT          428 a          167 c          168 g          411 t
ORIGIN      
        1 ttaatatcta atatttaaaa tacaatgaat aaaaaacgag tcctattaat tgctagttat
       61 gattcttttt tgaatactgg atatgctgtt gcaaaagaaa ttaactattc aacaatcgat
      121 atttatatcc accaaacaaa aaaaaatatt ctttcggaat cacaattaag tttaaatggg
      181 ctttctttaa aagaaatcaa tttttttcat attgatgatt atttcgacaa attaatgtac
      241 cagaattatg atattgttat tctatcatta ggtaatggtt tactgacgcg tttttttcgg
      301 aatagtagca aacttaattt aacattacct atagtaatta ctctatttcc aggggtaatt
      361 tttggtgatt cagaaagtat tataactagg ttaggtgcta atattttatt gttcaataat
      421 tattatgatt accaaatagg caataagttc aaagaacgtt acaacttatc gtgtacaaat
      481 attttatatg gttatcctat cctacgaaaa aaacaccatt gctctgatgg caataaagtt
      541 tatttcattg atcaagtaaa aattccagat ggaaaaaaag aaagattatt aattctaaaa
      601 aaattaatag cactggctaa tcgctatcca cataaagatt tagtactatt attacgtgtc
      661 catcaaaatg atatcacagt acatgaagat aaatactctt atgctgaatt agcaaaaaat
      721 atgaaattgc ctgataattt taaaatagag agaaaacgga cacaagatgc cttacaagaa
      781 atgggatatt gtttatcatt ctcttcaaca atgttatttg aagctgaaag ctgcggaatt
      841 cctattggtg tcattagtga tttaggggtt gacaagaaat atgccaatac acatttcaaa
      901 gatagtggtg ttttggttaa tttagatacg gtagacttgg actctccaaa taccattaat
      961 ccaacttggg ctgaactata tactaatcca gatagcctct cttcaaaaga gtttaaccaa
     1021 ttattagagg ttacttctac tcaaccacct agttttgata attattttat tgcagttaat
     1081 gacgttcagc ctgtatctat ggttctgtta cgtaaattta aaaagcttat atatcatcct
     1141 aagcaattct ttgttgattc aaaactatat aaaa
//
LOCUS       DAXISH010000124         1144 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.124, whole genome shotgun sequence.
ACCESSION   DAXISH010000124 DAXISH010000000
VERSION     DAXISH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1144
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.124"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..>1144
                     /gene="tuf"
                     /locus_tag="ACFOV4_002057"
     CDS             <1..>1144
                     /gene="tuf"
                     /locus_tag="ACFOV4_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012081251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFC7619990.1"
                     /translation="RSKPHVNVGTIGHVDHGKTTLTAALTTILAKKFGGAAKAYDQID
                     NAPEEKARGITINTSHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAA
                     DGPMPQTREHILLARQVGVPYIIVFMNKCDMVDDAELLELVEMEIRDLLSSYDFPGDD
                     CPIVQGSALKALEGDAAYEEKIFELAAALDSYIPTPERAVDKPFLLPIEDVFSISGRG
                     TVVTGRVERGIIHVGDEIEIVGLKETQKTTCTGVEMFRKLLDEGQAGDNVGVLLRGTK
                     REDVERGQVLAKPGTITPHTKFKAEVYVLSKEEGGRHTPFFANYRPQFYFRTTDVTGA
                     VTLEEGVEMVMPGENVTITVELIAPIAMEEGLRFAIREGGRTVGAGV"
BASE COUNT          297 a          320 c          301 g          226 t
ORIGIN      
        1 acgtagcaaa ccgcacgtaa acgttggcac catcggtcac gttgaccatg gtaaaaccac
       61 cctgactgcc gctttgacta ctattttggc taaaaaattc ggtggtgctg caaaagctta
      121 cgaccaaatc gacaacgcac ccgaagaaaa agcacgcggt attaccatta acacctcgca
      181 cgtggaatac gaaaccgaaa cccgccacta cgcacacgta gactgcccgg ggcacgccga
      241 ctacgttaaa aacatgatta ccggcgccgc acaaatggac ggtgcaatcc tggtatgttc
      301 cgcagccgac ggccctatgc cgcaaacccg cgaacacatc ctgctggccc gtcaagtagg
      361 cgtaccttac atcatcgtgt tcatgaacaa atgcgacatg gtcgacgatg ccgagctgtt
      421 ggaactggtt gaaatggaaa tccgcgacct gctgtccagc tacgacttcc ccggcgacga
      481 ctgcccgatt gtacaaggtt ctgcactgaa agccttggaa ggcgatgccg cttatgaaga
      541 gaaaatcttc gaactggctg ccgcattgga cagctacatc ccgactcccg agcgtgccgt
      601 ggacaaaccg ttcctgctgc ctatcgaaga cgtgttctcc atttccggcc gaggtacagt
      661 agtaaccggc cgtgtagagc gcggtatcat ccacgttggt gacgagatcg aaatcgtcgg
      721 tctgaaagaa acccaaaaaa ccacctgtac cggtgttgaa atgttccgca aactgctgga
      781 cgaaggtcag gcgggcgaca acgtaggcgt attgctgcgc ggtaccaaac gtgaagacgt
      841 ggaacgcggt caggtattgg ccaaaccggg tactatcact cctcacacca aattcaaagc
      901 agaagtgtac gtactgagca aagaagaggg cggccgccat actccgttct tcgccaacta
      961 ccgtccgcaa ttctacttcc gtaccaccga cgtaaccggc gcggttactt tggaagaagg
     1021 tgtggaaatg gtaatgccgg gtgagaacgt aaccattacc gtagaactga ttgcgcctat
     1081 cgctatggaa gaaggcctgc gctttgcgat tcgcgaaggc ggtcgtaccg tgggtgccgg
     1141 cgtg
//
LOCUS       DAXISH010000125         1122 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.125, whole genome shotgun sequence.
ACCESSION   DAXISH010000125 DAXISH010000000
VERSION     DAXISH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.125"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            118..1071
                     /locus_tag="ACFOV4_002058"
                     /pseudo
     CDS             118..1071
                     /locus_tag="ACFOV4_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611093.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT          293 a          289 c          321 g          219 t
ORIGIN      
        1 ctgaaggcga tgtgtttgaa cctgttgaaa gcggccaaca ggctaagtgc gcccgctgcc
       61 gcctaaaagg cggcccggat gcctgattat cgggtatccg gagaggatta aggggggatt
      121 tgggtagaat taggcggtat ttggggcgaa aacagccgaa aacagctgaa aacagctgaa
      181 aacagctgaa aacctgtgtt tgggtttcgg ctgtcgggag ggaaaggaat tttgcaaagg
      241 tctcaggtcg ccctcgtcgt gacggaaagt actggcggtc tcgaaatccc cgccgccaaa
      301 gccatccgcc gagcaggcat agccgtgatt atcgccaacc cgcgtcagac gcatcagttt
      361 gcccaatcgc agccgctgac caaaaccgac gccaaagatg ccaaaatgcc cgccttcttc
      421 gcacagatga cggcacagaa agaagattcg caaaccatgc cctaccaacc gcccaccgaa
      481 gcggaagaag tgttggaagc cttggttaac cgccgcaacc aaccggcgga tatgcggact
      541 gccgagaaaa accgtctgca tcaggttcac gaaacgcaag tcggaagcgt caaacaactg
      601 attgcccatt ttgaccggct gattgacgaa ttggacaaac aaatcgacaa ccacacccac
      661 acgcattttg acggcaaaga ccaagtggcg gagcaaatca aaggcatcgg ttcgataacg
      721 acggctacgc tgatggcgat gttgcccgaa ttggggcggc tgtcgcacaa acggatagcg
      781 ggtttggccg gcattgcccc gcacccgagg gagggcgggg aaaccaaatt caaaagccgc
      841 tgctttggcg gaaggtctgc ggtgcgtaaa gcactgtata tggctaccgt ggcagcgaca
      901 cgttttgaac cgcttattcg ggatttccac caacgcccgc tgtccgaggg taagccgtat
      961 aaggttgccg ttacggcatg tatgcgcaaa ctgctgacga tatcgaatgc ccggatgcgt
     1021 gattattttg ccgaaaacga taccgccgaa aacggtatcc ggacggcttg atttgagttt
     1081 tggtattttt gcccgacggg gtgaaaaata cagttgcttt tt
//
LOCUS       DAXISH010000126         1067 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.126, whole genome shotgun sequence.
ACCESSION   DAXISH010000126 DAXISH010000000
VERSION     DAXISH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1067
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.126"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            1..522
                     /locus_tag="ACFOV4_002059"
                     /pseudo
     CDS             1..522
                     /locus_tag="ACFOV4_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          322 a          254 c          254 g          237 t
ORIGIN      
        1 gaactgatta accgccaact gaccgaaaaa aacctaaaaa tagagaaagc atccgccgcc
       61 gtcattgacg ccaccattat tcagaccgcc ggcagcaaac agcgtcaggc catagaagtc
      121 gatgaagaag gacaagtcag cggccaaacc acaccgagta aagacagcga tgcccgttgg
      181 acaaagaaaa acggcctcta cagactcggt tacaaacaac atacccgtac cgatgcggaa
      241 ggctatatcg agaaactgca catcacccca gccaataccc atgagtgcaa ccacctgttg
      301 cctttgctgg aaggcattac cgaaggcacg accatctatg ccgacaaagg ctatgacagt
      361 gcggaaaacc gaacatctgg aagaacatca gttgttagac ggcattatgc gcgggcagcc
      421 tatttcggac tgattaaagt gagtgcgcaa agccacctga aggcgatgtg tttgaacctg
      481 ttgaaagcgg ccaacaggct aagtgcgccc gctgccgcct aaaaggcagc ccggatgcct
      541 gattatcggg tatccgggga ggattaaggg ggtatttggg tagaattagg cggtatttgg
      601 ggcgaaaaca gctgaaaacc tgtgtttggg tttcggctgt cgggagggaa aggaattttg
      661 caaaggtctc atcctgttat tttcacaaaa acagaaaacc aaaaacagca acctgaaatt
      721 cgtcattccc acgaaagtgg gaatccagtt tcttgagttt cagtcatttc cgataaattg
      781 ccttagcatt gaatgtctag attcccgcct gcgcgggaat gacggcggag cggtttctgt
      841 tttttccggt aaatacccac aagctgaaat cccgttattt tcacaaaaac agaaaaccaa
      901 aaacagcaac ctgaaattcg tcattcccgc gcaggcggga atccagttcg ttgagtttca
      961 gctatttaga ataaattttg aaactctaat cccgtcattc ccacgaaagt gggaatccag
     1021 ttttttgagt ttcagtcatt tccgataaat tgccttagca ttgaatg
//
LOCUS       DAXISH010000127         1050 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.127, whole genome shotgun sequence.
ACCESSION   DAXISH010000127 DAXISH010000000
VERSION     DAXISH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.127"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..911)
                     /gene="mafB"
                     /locus_tag="ACFOV4_002060"
     CDS             complement(<1..911)
                     /gene="mafB"
                     /locus_tag="ACFOV4_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 3"
                     /protein_id="HFC7619991.1"
                     /translation="MNLPIQKFMMLFAAAISLLQIPISHANGLDARLRDDMQAKHYEP
                     GGKYHLFGDGRGSVKNRVYAVQTFDATAVGPILPITHERTGFEGVIGYETHFSGHGHE
                     VHSPFDHHDSKSTSDFSGGVDGGFTVYQLHRTGSEIHPEDGYDGPQGSDYPPPGGARD
                     IYSYYVKGTSTKTKTNIVPQAPFSDRWLKENAGAASGFFSRADEAGKLIWESDPNKNW
                     WGNRMDDIRGIIQGAANPFLTGFQGLGVGAITDSAVNPVTYAAARKTLQGIHNLGNLS
                     PEAQLAAATALQDSAFAVKDGINSAKQ"
     gene            complement(951..>1050)
                     /locus_tag="ACFOV4_002061"
     CDS             complement(951..>1050)
                     /locus_tag="ACFOV4_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFC7619992.1"
                     /translation="TGNSAPSVEADNSHEGYGYSDEVVRQHRQGQP"
BASE COUNT          241 a          261 c          242 g          306 t
ORIGIN      
        1 cattgtttgg cagagttgat accgtctttt accgcaaaag cactgtcttg taatgcggtt
       61 gcggccgcaa gttgtgcttc cggacttaaa tttcctaaat tgtgaatacc ctgtaaagtt
      121 ttccgtgctg ccgcataggt taccgggttt accgcactgt ctgtaattgc cccaactccc
      181 aatccctgaa aacccgttag aaaaggattg gctgcacctt ggatgatgcc gcgaatatca
      241 tccatacggt taccccacca atttttattg gggtcgcttt cccatatcag ttttcctgct
      301 tcatccgcac ggctgaaaaa accagaggcg gcaccggcat tttcttttag ccaacggtct
      361 gaaaatgggg cttgagggac aatattagtc tttgtttttg ttgaagttcc tttgacatag
      421 tagctgtata tatcccttgc tcctccgggg ggcggataat cgctgccttg cggtccgtca
      481 tatccatcct ccggatggat ttccgaccct gtccgatgaa gttggtaaac agtaaaaccg
      541 ccgtctacac cgccgctgaa atcagaagtg ctttttgaat catgatgatc gaacggactg
      601 tgtacttcat gtccgtgccc tgaaaaatgg gtttcatagc cgataacacc ttcaaaccct
      661 gtccgttcgt gtgtaatagg cagtatgggg ccgaccgcag ttgcatcaaa tgtttggacg
      721 gcgtaaaccc gatttttaac actgccgcga ccatcaccga acagatggta tttgccaccc
      781 ggttcgtagt gttttgcctg catatcatcg cgcaaacggg catccaaacc gttcgcatga
      841 ctaatgggga tttgcagcaa cgatattgct gctgcaaaca gcatcatgaa tttttgaata
      901 ggcaaattca ttttgttttc cttggtagca agcggttatg gtagtgtgaa tcaaggttgc
      961 ccttgtctat gttgtcgcac tacttcatcg ctgtatccat acccctcatg actgttatca
     1021 gcctctacgg atggggcgga gttacccgta
//
LOCUS       DAXISH010000128         1032 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.128, whole genome shotgun sequence.
ACCESSION   DAXISH010000128 DAXISH010000000
VERSION     DAXISH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.128"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..101
                     /locus_tag="ACFOV4_002062"
     CDS             <1..101
                     /locus_tag="ACFOV4_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC7619993.1"
                     /translation="KSFPLFLKECEFRFNFGTPSQQLKILRDWCGI"
BASE COUNT          261 a          248 c          264 g          259 t
ORIGIN      
        1 gcaaatcttt cccgctgttc ttgaaagaat gcgaatttcg atttaacttc ggcacaccgt
       61 ctcaacagct taaaatcctg cgggattggt gtggaattta gggctaatct agtacagccc
      121 cttagattta attcactata cctgcgtaat ggtatcgggt actcatcatc aacctgcctt
      181 gcattcggtt gtgttgtccg gcaactgtcc ggttgtgtcg atgggttgcc ctgccgctcc
      241 ctgtgctacg caacggttgt gtgccttggg tgggcgcggg tggcggccgg gcggtttgtt
      301 gctatgatac gggagttccg atatacaagg gtgggcttca gcccaccaat caacgaccga
      361 aaaagaaaaa acgttgggct gaagcccact ctacgcaatt acgcaactgt tatcgtgggg
      421 atgacgggat tttaggtttt tgtttttctg tttttgcggg aaggatgggt tttaggttgc
      481 ggtcatttat cggaaaagca gaaatcgctc cgccgtcatt cccgcgaaag cgggaatctg
      541 aacacgtccg tagggaaacc tatatcccgt cattcccacg aaagtgggaa tctagaacct
      601 ctgaattttc agacaacctt tgaatattgc cgccgtcccg cgttctagat tcccgcctgc
      661 gcgggaatga cgattcatca gtttcccgaa acgcccgaaa aaccgaaacc gagcaaaccg
      721 gattcccgcc tgcgcgggaa tgacgattta taagtttccc gaaacgccca aaaaaaccga
      781 aatccgacag gcaggatttt tgctttcgtg gggatgacgg gattttaagt tacggtcatt
      841 tatcggaaaa gcagaaactg ctccgccgtt attccagcga aggcgggaat ctgaacacgt
      901 ccgcacggaa acctatagtg gattaacaaa aatcaggaca aggcgacgaa accgcagaca
      961 gtacagatag tacggcaagg cgaggcaacg ccgtactggt ttaaatttaa tccactataa
     1021 tcctgttgct ta
//
LOCUS       DAXISH010000129         1022 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.129, whole genome shotgun sequence.
ACCESSION   DAXISH010000129 DAXISH010000000
VERSION     DAXISH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1022
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.129"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            147..413
                     /locus_tag="ACFOV4_002063"
     CDS             147..413
                     /locus_tag="ACFOV4_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619994.1"
                     /translation="MDFEFGFRTLWPIATAAFWFWVNGISGRLKEADKRIDDLKEELH
                     AVKLSYHTKQDAKADRDNIAASLGRIENKLEKVNEKLDRKADKS"
     gene            410..607
                     /locus_tag="ACFOV4_002064"
     CDS             410..607
                     /locus_tag="ACFOV4_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7619995.1"
                     /translation="MSDPILEALARIENKTDQTLKNQKEMQAEIAQIRQDTKRTAITF
                     GALGGGVITVGWELLKAKMGL"
     gene            610..>1022
                     /locus_tag="ACFOV4_002065"
     CDS             610..>1022
                     /locus_tag="ACFOV4_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1804 family protein"
                     /protein_id="HFC7619996.1"
                     /translation="MAHPQEIREKLRRLYVSGEQTLETAALMCEIPQTTARAWKRADK
                     EKGDDWDKMRAAYTLAGGGIEDLSRAMLAGFMVQYNSTMTMLQDSSTEDLPPSDRAKL
                     LASLADAFTKTVSANARVMPETSKLATALELIEFL"
BASE COUNT          267 a          230 c          306 g          219 t
ORIGIN      
        1 acctttaaac gtgcggtttg gcaaactttg ggggcgtatt actgtgtttg taatgatggt
       61 gatggactgg agattgccag caatcgccct gacggttacg ccgtccgtat cgtattcggc
      121 gatgtgccgg tttaaagggg ttttaaatgg actttgaatt tggtttcaga accctgtggc
      181 cgattgcgac ggcggcattt tggttttggg tcaacggcat ttcaggccgt ctgaaagagg
      241 cggacaagcg tatcgacgac ctgaaagagg agctgcacgc ggtcaagctc tcttatcaca
      301 ccaagcaaga tgccaaggca gaccgcgaca atattgcggc ttcgttggga cgcatcgaaa
      361 acaagttgga aaaagtaaac gaaaaactgg acaggaaagc agacaaatca tgagcgaccc
      421 gattttggaa gccttggcgc gtattgaaaa caagactgat caaacgctga aaaatcagaa
      481 agaaatgcag gcggaaattg cgcaaatccg ccaagacacg aaacgcacgg ccattacatt
      541 cggcgcactg ggcggcggcg tgattacggt cggctgggaa ttgcttaaag cgaaaatggg
      601 actgtaatta tggctcaccc gcaagaaatc cgtgaaaagt tacgtcggct ctatgtgagc
      661 ggcgagcaaa ctttggaaac ggcggccttg atgtgcgaaa tcccgcagac cactgcgcgt
      721 gcgtggaaac gtgcggataa ggaaaaaggc gacgactggg ataagatgcg cgccgcctac
      781 actttggccg gcggcggtat tgaggacttg agccgtgcga tgttggccgg ttttatggtg
      841 cagtacaaca gcacgatgac gatgctgcag gattcgagta ccgaagattt gcccccgtcc
      901 gaccgcgcca agctgttggc cagcctggcc gatgcgttta cgaaaaccgt atcggccaat
      961 gcgcgtgtga tgccggaaac gtcaaaactg gcgacggctt tggaattgat tgagttcttg
     1021 at
//
LOCUS       DAXISH010000130          962 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.130, whole genome shotgun sequence.
ACCESSION   DAXISH010000130 DAXISH010000000
VERSION     DAXISH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.130"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..496
                     /locus_tag="ACFOV4_002066"
     CDS             <1..496
                     /locus_tag="ACFOV4_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFC7619997.1"
                     /translation="PLASLLLPENYAAVRFIVVSCMLPPLFCTLVEISGIGLNVVRKT
                     RPIALATLGALAANLLLLGLAVPSGGARGAAVACAASFWLFFVFKTESSCRLWQPLKR
                     LPLYMHTLFCLASSAAYTCFGTPANYPLFAGVWAAYLAGCILRHRKDLHKLFHYLKKQ
                     GFPL"
     gene            493..>962
                     /locus_tag="ACFOV4_002067"
     CDS             493..>962
                     /locus_tag="ACFOV4_002067"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC7619998.1"
                     /translation="MKIVLTTSMAGLGGTETATVRLGRLLKRRGHDIILASSDGPFVG
                     EAQASGIRWQPVDFYRGGLAGYLKSTFAYARMLRREQPDIIDCQMARVVPACALAAKI
                     VSPKTKIIYHSHGLDAATYPKIAKLFDKLGVYIIGNCKHEREKLIRHGFPASRIA"
BASE COUNT          177 a          322 c          257 g          206 t
ORIGIN      
        1 gcccctcgcc tccctcctgc tgccggaaaa ctacgccgcc gtccggttta tcgtcgtatc
       61 gtgtatgctg ccgccgctgt tttgcacgct ggtagaaatc agcggcatcg gtttgaacgt
      121 cgtccgaaaa acacgcccga tcgcgctcgc caccttgggc gcgctggcgg caaacctgct
      181 gctgctgggg cttgccgtac cgtccggcgg cgcgcgcggc gcggcggttg cctgtgccgc
      241 ctcattttgg ctgttttttg ttttcaagac cgaaagctcc tgccgcctgt ggcagccgct
      301 caaacgcctg ccgctttata tgcacacatt gttctgcctg gcctcctcgg cggcctacac
      361 ctgcttcggc acgccggcaa actaccccct gtttgccggc gtatgggcgg catatctggc
      421 aggctgcatc ctgcgccacc ggaaagattt gcacaaactg tttcattatt tgaaaaaaca
      481 agggtttcca ttatgaaaat cgttttgacc acatctatgg caggcttggg cggcacggaa
      541 accgccaccg tccgcctcgg gcggctgctc aaacggcgcg ggcacgacat catccttgct
      601 tcttcggacg ggccttttgt cggagaggcg caagcatcgg gcatccgttg gcagccggtt
      661 gatttttacc ggggcgggct tgccggctac ctcaaaagca cctttgccta cgcccggatg
      721 ctgcgccgcg aacaacccga catcatcgac tgccaaatgg cgcgcgtcgt tccagcctgc
      781 gcccttgccg ccaaaatcgt ttcgccgaaa accaaaatca tctaccactc gcacggtttg
      841 gacgcggcaa cctaccccaa aatcgccaag ctcttcgaca agctgggcgt gtacatcatc
      901 ggcaactgta aacacgagcg cgaaaaactc atccgccacg gcttccccgc cagccggatt
      961 gc
//
LOCUS       DAXISH010000131          919 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.131, whole genome shotgun sequence.
ACCESSION   DAXISH010000131 DAXISH010000000
VERSION     DAXISH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.131"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            840..919
                     /locus_tag="ACFOV4_002068"
                     /pseudo
     CDS             840..919
                     /locus_tag="ACFOV4_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060537127.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter"
BASE COUNT          312 a          206 c          184 g          217 t
ORIGIN      
        1 aataatctcc aatctgttga cgtgaagccc cattccggaa atatccattt ggatgccaaa
       61 ggaaaaattc aatttaattt gaatgttccc gatgttgatg gggtacaaga tgtagccagt
      121 gaaaaaaata ccgacaaaca atagtgcctt agttcggtat gtcaacacta tcagcccccc
      181 gatgaaaatg acaaaggcag catatccttt cattcaaaaa caggcaattt gttcaatatg
      241 aacgttaaag ttcataaaga cacacaccat ttcggtattc acaacctcaa caataccgat
      301 gttcatctga ctgccgaaga cagcgataat gtgattgaga ttaaagggga actcgccgac
      361 cctatgccga caggaaatgt tgagagtaca agttttttaa ggggcattga aacggctttt
      421 aaatccaata ccgtattaac ggggaataac aataaaatat ccatcgccac tgagggcaag
      481 ggcttgggat tgggcgtaaa tggtctccag tccaactccc cctattccgg acacacgacg
      541 ggcattttca tcaataatca atcaagcgac cttacccaac cttcccttga tggcatcagc
      601 accatcaaac tcaaagccgt caagggaaat aatgaagttg atttaaatgt aaaaaaccac
      661 gcctccgtaa aaggcattat cgcgtcgcat tctgcaaaag caacgcttga agccgaaggg
      721 gacaatattg tccaggttaa aaatccggac accaatacgg ctttaatcga tgctttgaaa
      781 aaacaatacc ccaatgcttc gaaagaacta tacagggtgg gggttcaatc cacgactgga
      841 acagtacgca tttcgccaaa cggcaaaatc gcattaacgg aattgaaaac ttttggaatt
      901 gtacaaaacg gcatttgcg
//
LOCUS       DAXISH010000132          900 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.132, whole genome shotgun sequence.
ACCESSION   DAXISH010000132 DAXISH010000000
VERSION     DAXISH010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..900
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.132"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..895
                     /locus_tag="ACFOV4_002069"
     CDS             <1..895
                     /locus_tag="ACFOV4_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element IS1655 family transposase"
                     /protein_id="HFC7619999.1"
                     /translation="EIAKQLNRHKSTISREIRRHRTQGQQYSAEKAQRQSRTIKQRKR
                     QPYKLDSQLIQHIDTLIRRKLSPEQVCAYLCKHHQITLHHSTIYRYLRQDKSNGSTLW
                     QHLRICSKPYRKRYGSTWTRGKVPNRVGIENRPAIVDQKSRIGDWEADTIVGKGQKSA
                     LLTLVERVTRYTIICRLDSLKAEDTARAAVRALKAHKDRVHTITMDNGKEFYQHTKIT
                     KALKAETYFCRPYHSWEKGLNENTNGLIRQYFPKQTDFRNISDREIRRVQDELNHRPR
                     KTLGYETPSVLFLNLFQPLIH"
BASE COUNT          290 a          269 c          190 g          151 t
ORIGIN      
        1 cgaaatcgcc aaacagctga accgccacaa aagcaccatc agccgcgaaa tcagacggca
       61 ccgcacccaa gggcagcaat acagcgccga aaaagcccag cggcaaagcc ggactatcaa
      121 acagcgtaag cgacaaccct ataagctcga ttcgcagctg attcagcaca tcgacaccct
      181 tatccgccgc aaactcagtc ccgaacaagt atgcgcctac ctgtgcaaac accaccagat
      241 cacgctccac cacagcacca tttaccgcta ccttcgccaa gacaaaagca acggcagcac
      301 gttgtggcaa catctcagaa tatgcagcaa accctaccgc aaacgctacg gcagcacatg
      361 gaccagaggc aaagtcccca accgtgtcgg catagaaaac cgacccgcta tcgtcgacca
      421 gaaatcccgt atcggcgatt gggaagccga caccattgtc ggcaaaggac agaaaagcgc
      481 attattgacc ttggtcgaac gcgttacccg ctacaccatc atctgcagat tggatagcct
      541 caaagccgaa gacactgccc gggcagctgt tagggcatta aaggcacata aagacagggt
      601 gcacaccatt accatggata acggcaaaga gttctaccaa cacaccaaaa taaccaaagc
      661 attgaaagcg gagacttatt tttgtcgccc ttaccattct tgggagaaag ggctgaatga
      721 gaacaccaac ggactcatcc ggcaatactt ccccaaacaa accgatttcc gtaacatcag
      781 tgatcgggag atacgcaggg ttcaagatga gttgaaccac cgaccaagaa aaacacttgg
      841 ctacgaaacg ccaagtgttt tattcttgaa tctgttccaa ccactaatac actagtgttg
//
LOCUS       DAXISH010000133          885 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.133, whole genome shotgun sequence.
ACCESSION   DAXISH010000133 DAXISH010000000
VERSION     DAXISH010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..885
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.133"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            219..>885
                     /locus_tag="ACFOV4_002070"
     CDS             219..>885
                     /locus_tag="ACFOV4_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFC7620000.1"
                     /translation="MFPDKYKLSLEENIFLAKKVLVAQIHNLSRFENCQTTLLQTEQI
                     IHGKNVASASLEDIQTILNLKRAYQYVISHISNGEPVDISLLKKINNIVAKDDSLAPG
                     DFRTGSVGVTLLDGSRHAPNPVKEIEVARVLQNIGLQSGSTTEAAVRFMLYCMRQQVF
                     WDGNKRTATLFANGLMMAGGCGILEISEMQMPQFNEKLSAFYRSGDDTDISKFVYQNC
                     ISGI"
BASE COUNT          251 a          195 c          203 g          236 t
ORIGIN      
        1 cggatgaaat caaccgatat tcaaacacag tcatttttag cgcattttca gcgtatcgtt
       61 aatgcggaaa atttcgtgaa caggtttttt gcacaggtct ccgcctcgtt tcgcgggatg
      121 ggaaaccgta ttagaaaacg gacgcacgca acataaaccc cgaaagtgat gataagatga
      181 tgatttaacg tactgcttta attatttaag gaattatcgt gtttcccgac aaatacaagt
      241 tgagtttgga agaaaatatt tttctggcaa agaaagtatt ggttgcccaa attcacaacc
      301 tcagccgttt tgagaattgt cagacgacct tgttgcagac cgaacaaatt atccatggca
      361 aaaatgtagc ctccgcgtca ctggaagaca tccaaaccat cttgaacctg aaacgtgcct
      421 atcaatatgt gatttcgcat atttcaaacg gcgaaccggt cgatatttca ctccttaaaa
      481 aaatcaacaa cattgttgcc aaggacgatt ctttggcacc cggtgatttc cgtaccggtt
      541 cggtcggcgt aacgctattg gacggttccc gtcatgcccc aaatccggtg aaggaaattg
      601 aagtggctcg cgtgttacaa aatatcggac tgcaaagcgg ttcgacgacg gaggcagccg
      661 tccgttttat gctttattgt atgcggcagc aggttttttg ggacggcaac aaacgaacgg
      721 caaccttatt tgccaacggt ctgatgatgg cggggggctg cggcatcttg gaaatctccg
      781 aaatgcagat gccgcaattc aatgaaaaac tgtccgcatt ctatcgctcc ggcgacgata
      841 ccgatatttc caagtttgtg tatcaaaatt gtatatcggg catag
//
LOCUS       DAXISH010000134          875 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.134, whole genome shotgun sequence.
ACCESSION   DAXISH010000134 DAXISH010000000
VERSION     DAXISH010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.134"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..173)
                     /locus_tag="ACFOV4_002071"
     CDS             complement(<1..173)
                     /locus_tag="ACFOV4_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC7620001.1"
                     /translation="MKYRRCYRNGGTYFFTVVTDKRQKILTDDAVRLALRQAVMAVRE
                     RYPFEILAWVLMP"
     gene            complement(798..>875)
                     /locus_tag="ACFOV4_002072"
     CDS             complement(798..>875)
                     /locus_tag="ACFOV4_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="opacity family porin"
                     /protein_id="HFC7620002.1"
                     /translation="YHNWGRLENTRFKTHEVSLGVRYRF"
BASE COUNT          211 a          197 c          246 g          221 t
ORIGIN      
        1 tcgggcatca acacccatgc caaaatttca aacggatacc gttcgcgcac cgccattacc
       61 gcctgccgta aagccaaacg caccgcatca tcggtcaaaa tcttctgccg tttatcggtt
      121 acaaccgtaa aaaagtaagt gccaccattg cggtaacaac gacggtattt cataatgtta
      181 tgctcggaat gattttgtag gtcggattct tgaattcgac attttgggca ttgctgcaat
      241 ggattgcaat gatgggaatg ttaaaggttt tgtcggatac aagtatccga cctacgcttg
      301 ctgaaccgtc attcccacgg aagtgggaat ctagaacgcg gggtttcagt catttccgat
      361 agattcccgc cgcgtcaggg ggctggattc ccgcctgcgc gggaatgacg ggtttcaaga
      421 ttacggtgtt gtcggaacga aactgaatcg tcattcccac gaaagtggga atctagaatc
      481 tcggggtttc agtcatttcc gatagattcc cgccgcgtcg ggggtctgga ttcccgcctg
      541 cgcaggaatg acgggtttcg agattgcgtt gttgtcggga atgcaactga accgtcattc
      601 ccacggaagt gggaatctag gacgtaaaat ctaaagaaac cgttttatcc gataagtttc
      661 tgtgcggaca ggtctggatt cccgcctgcg cgggaatgac gggtttcgag attacggtgt
      721 atcgggaatg atgggaaacg gtgggaattg tgtaaaaaat gccgtctgaa ggttcagacg
      781 gcatcggtat cggggaatca gaagcggtag cgcacgccca atgagacttc gtgggttttg
      841 aagcgggtgt tttccaagcg tccccagttg tggta
//
LOCUS       DAXISH010000135          855 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.135, whole genome shotgun sequence.
ACCESSION   DAXISH010000135 DAXISH010000000
VERSION     DAXISH010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.135"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            76..705
                     /locus_tag="ACFOV4_002073"
     CDS             76..705
                     /locus_tag="ACFOV4_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFC7620003.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGIKVLLLGDSDGEAIAKEGLRK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFVAVVYLGLGVYILIENNSFDMLWTVSGQEKIL"
BASE COUNT          230 a          134 c          171 g          320 t
ORIGIN      
        1 gatggggttg aagttgacat ctacaaagtt taatgtttga atacattaaa aaaatatatt
       61 tgaatgagat gttttatgat tcaaaatgtt gttacttcaa taatcctgta ttctgggaca
      121 gccgtagact tacttattat cctaatgtta ttttttgcca aaagaaaaag cagaaaagac
      181 atcattaaca tctatttagg acaatttcta ggctctgtta gcctgatatt gctaagtttg
      241 ctttttgcat ttgtcttaga ttatattcct agtaaagaga ttttaggttt gctcggcttg
      301 attccaattt tcctaggcat caaagttttg ctgttaggag attctgatgg agaggctatt
      361 gccaaagagg gtttgcgcaa agataataaa aacctgattt ttctagtcgc tatgattact
      421 tttgcaagtt gtggtgctga caatattggt gtctttgttc catattttac taccttaaat
      481 ttagcgaatt tgatagtggc tttacttacc tttctagtca tgatttatct cttggttttt
      541 tctgcccaaa aattagcaca agtcccttct gttggagaaa ctttggaaaa atatagcaga
      601 tggtttgttg ctgttgttta tttgggattg ggggtatata tcctgattga aaacaacagt
      661 tttgatatgc tatggactgt gtcgggccag gaaaaaatat tatgaaaaag atagtatctg
      721 caaagactgc catgtgcagt cttttttgtt gccggtcttt ttgtgtctga tgccgtctga
      781 agcagtctct gcacgacctt tgtgcgaata tttgctacac ttggcaatcc gtccatttct
      841 tctcacgctt atgct
//
LOCUS       DAXISH010000136          850 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.136, whole genome shotgun sequence.
ACCESSION   DAXISH010000136 DAXISH010000000
VERSION     DAXISH010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.136"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..78
                     /locus_tag="ACFOV4_002074"
     CDS             <1..78
                     /locus_tag="ACFOV4_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="opacity family porin"
                     /protein_id="HFC7620004.1"
                     /translation="YHNWGRLENTRFKTHEVSLGMRYRF"
BASE COUNT          217 a          264 c          193 g          176 t
ORIGIN      
        1 taccacaact ggggacgctt ggaaaacacc cgcttcaaaa cccacgaagt ctcattgggc
       61 atgcgctacc gcttctgatt ccccgacacc gatgccgtct gaaccttcag acggcatttt
      121 tgattcacct gccgtttaca gacgcggggc gggcgtggaa atacccaaac cgtcattccc
      181 gacaacaccg taatcttgaa acccgccatt cccgataaca gcgcaatctt gaaacccgtc
      241 attcccgaca acaccgtaat ctcgaaattc gtcattcccg cgcaggcggg aatccaaacc
      301 cccgacgcgg cgggaatcta tcggaaatga ctgaaacccc gagattctag attcccactt
      361 ccgtgggaat gacggttcag ttgcgttccg acaacaccgt aatcttgaaa tccgtccgac
      421 aacaccgtaa tcttaaaacc cgtcattccc gcgcaggtgg gaatccagac cccctgacgc
      481 ggcgggaatc tatcggaaat gactgaaacc ccgagattct agattcccac tttcgtggga
      541 atgacgtggt gcaggtttcc gtatggatgg attcgtcatt cccgacaaca ccccaatctt
      601 gaaacccgtc attcccgcac aggcgggaat ccagacctgt ccgcacagaa acttatcgga
      661 taaaaacagt tgcccaaacc ccgcgttcta gattcccact tccgtgggaa tgacgtggtg
      721 caggtttccg tatggatgga ttcgtcattc ccgacaacac cgtaatctcg aaattcgtca
      781 ttcccgcgca ggcgggaatc cagccccctg acgcggcggg aatctatcgg aaatgactga
      841 aaccccgaga
//
LOCUS       DAXISH010000137          841 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.137, whole genome shotgun sequence.
ACCESSION   DAXISH010000137 DAXISH010000000
VERSION     DAXISH010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..841
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.137"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..>841
                     /locus_tag="ACFOV4_002075"
     CDS             <1..>841
                     /locus_tag="ACFOV4_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
                     /protein_id="HFC7620005.1"
                     /translation="AVVGEIVGEALTNGKNPDTLTAKEREQILAYSKLVAGTVSGVVG
                     GDVNAAANAAEVAVKNNQLSDKEGREFDNEMTACAKQNNPQLCRKNTVKKYQNVADKR
                     LAASIAICTDISRSTECRTIRKQHLIDSRSLHSSWEAGLIGKDDEWYKLFSKSYTQAD
                     LALQSYHLNTAAKSWLQSGNTKPLSEWMSDQGYTLISGVNPRFIPIPRGFVKQNTPIT
                     NVKYPEGISFDTNLKRHLANADGFSQKQGIKGAHNRTNFMAELNSRGGRVKSETQTDI
                     EGIT"
BASE COUNT          288 a          156 c          190 g          207 t
ORIGIN      
        1 gtgcggtcgt gggggagatt gtcggggagg ctttgacaaa cggcaaaaat cctgacactt
       61 tgacagctaa agaacgcgaa cagattttgg catacagcaa actggttgcc ggtacggtaa
      121 gcggtgtggt cggcggcgat gtaaatgcgg cggcgaatgc ggctgaggta gcggtgaaaa
      181 ataatcagct tagcgacaaa gagggtagag aatttgataa cgaaatgact gcatgcgcca
      241 aacagaataa tcctcaactg tgcagaaaaa atactgtaaa aaagtatcaa aatgttgctg
      301 ataaaagact tgctgcttcg attgcaatat gtacggatat atcccgtagt actgaatgta
      361 gaacaatcag aaaacaacat ttgatcgata gtagaagcct tcattcatct tgggaagcag
      421 gtctaattgg taaagatgat gaatggtata aattattcag caaatcttac acccaagcag
      481 atttggcttt acagtcttat catttgaata ctgctgctaa atcttggctt caatcgggca
      541 atacaaagcc tttatccgaa tggatgtccg accaaggtta tacacttatt tcaggagtta
      601 atcctagatt cattccaata ccaagagggt ttgtaaaaca aaatacacct attactaatg
      661 tcaaataccc ggaaggcatc agtttcgata caaacctaaa aagacatctg gcaaatgctg
      721 atggttttag tcaaaaacag ggcattaaag gagcccataa ccgcaccaat tttatggcag
      781 aactaaattc acgaggagga cgcgtaaaat ctgaaaccca aactgatatt gaaggcatta
      841 c
//
LOCUS       DAXISH010000138          751 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.138, whole genome shotgun sequence.
ACCESSION   DAXISH010000138 DAXISH010000000
VERSION     DAXISH010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.138"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..180)
                     /locus_tag="ACFOV4_002076"
     CDS             complement(<1..180)
                     /locus_tag="ACFOV4_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC7620006.1"
                     /translation="MSYTQLTQGERYHIQYLSRHCTVTEIAKQLNRHKSTISREIRRH
                     RTQGQQYSAEKAQRQS"
     gene            complement(568..643)
                     /locus_tag="ACFOV4_002077"
     tRNA            complement(568..643)
                     /locus_tag="ACFOV4_002077"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Glu,seq:ttc)
BASE COUNT          164 a          176 c          210 g          201 t
ORIGIN      
        1 gctttgccgc tgggcttttt cggcgctgta ttgctgccct tgggtgcggt gccgtctgat
       61 ttcgcggctg atggtgcttt tgtggcggtt cagctgtttg gcgatttcgg tgacggtgca
      121 gtggcgggac aggtattgga tgtggtatcg ttcgccctgg gtcagttgcg tgtagctcat
      181 ggcaatcttt cttgcaggaa aggccgtatg ctaccgcata ctggcctttt tctgttaggg
      241 aaagttgcac ttcaaatgcg aatccgccgc cgtctgaaaa ttcagaagtt ctagattccc
      301 gttttcacgg gaatgacgaa gggttgtggg aatgacgaag tttcagacgg catcaaatgc
      361 tttgtcaggc ttcagacagc atcgtccacc ctctgccgtc attcccgcgc aggcgggaat
      421 ccagccttgt cggcacggaa acttatcgga taaaacggtt tcttcaaccc tacgctctag
      481 attcccgttt tcacgggaat gacgaagagt gtgagaatga cggttcataa ataaaaaaac
      541 ctgcttaaaa caagcaggtt tttgaattgg cacgcccacg gggattcgaa ccccggttgc
      601 cgccgtgaaa gggcagtgtc ctaggcctct agacgatggg cgcgtgggaa tgggcattat
      661 acatacttct agaaatttag caatacgatg ccgtctgaaa cttcgtcatt cccgcgaaag
      721 cgggaatcta gaatctccaa gttttcagac a
//
LOCUS       DAXISH010000139          698 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.139, whole genome shotgun sequence.
ACCESSION   DAXISH010000139 DAXISH010000000
VERSION     DAXISH010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.139"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..698)
                     /locus_tag="ACFOV4_002078"
     CDS             complement(join(<1..479,479..698))
                     /locus_tag="ACFOV4_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242698.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1301 family transposase"
                     /protein_id="HFC7620007.1"
                     /translation="MARTAITDNIWEQLQTTMKAHGCHQWKNDRTVMEAILWKLRTGA
                     PWRDIPIELGSWKTAYNRFNRWSKKGLWQKFFFDLRKEIDKEWVFIDGSYVRCHQHAS
                     GARRGFDRAIGQSRGGNTTKIHLCVDSHGNPLDFKVTGGNVHDGQVANDLIEVIQEAQ
                     YFIADKGYDSQEIRDKAIEHGMKAIIPKRKNAKKPNPDFDSYLYKLRHLVENAFARLK
                     QFRSIATRYEKLARN"
BASE COUNT          161 a          162 c          136 g          239 t
ORIGIN      
        1 attacgagct aatttctcat agcgagtagc aatactacga aactgcttta atcgtgcaaa
       61 tgcattctcg actaagtggc gtaatttata aaggtagcta tcaaaatcag ggttaggttt
      121 cttggcattt ttacgctttg gtataatagc tttcataccg tgttctatcg ctttatctct
      181 gatttcttgc gagtcatacc ctttgtcagc gataaaatac tgggcttctt gtatgacttc
      241 tatcaagtcg tttgcaactt gaccgtcgtg cacgttaccc ccagtgactt taaaatcgag
      301 cggatttcca tgcgagtcca cacataggtg tatttttgtc gtgtttccgc cacggctttg
      361 tccaattgct ctatcgaaac cacgccgagc tccacttgca tgttgatgac accgtacata
      421 acttccgtcg atgaataccc attctttgtc aatttctttt cgtagatcaa aaaaaaattc
      481 tgccacaagc cttttttaga ccatcggtta aagcggttat aagcggtttt ccatgaccct
      541 agctcaatag gtatgtctcg ccatggtgca cctgttctta gcttccatag tatggcttcc
      601 atcacggtac ggtcgttctt ccattgatga cagccgtgcg ctttcatggt tgtttgtaat
      661 tgttcccata tgttgtcagt tattgcggtt ctcgccat
//
LOCUS       DAXISH010000140          689 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.140, whole genome shotgun sequence.
ACCESSION   DAXISH010000140 DAXISH010000000
VERSION     DAXISH010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.140"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..281
                     /locus_tag="ACFOV4_002079"
     CDS             <1..281
                     /locus_tag="ACFOV4_002079"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7620008.1"
                     /translation="SGGNDVSVATVTVRFRLCWNFGKLMNRHSRAGGNLEFQCLKNLS
                     EKTKTLPPSFPRKWESRNEKQQEFIGNDRNRTDWIPAFAGMTATGLLL"
BASE COUNT          172 a          150 c          173 g          194 t
ORIGIN      
        1 aaagtggtgg gaatgacgtt tcagttgcta cggttactgt caggtttcgg ttatgttgga
       61 atttcgggaa acttatgaat cgtcattccc gcgcaggcgg gaatctggaa tttcaatgcc
      121 tcaagaattt atcggaaaaa accaaaaccc ttccgccgtc attcccacga aagtgggaat
      181 ctagaaatga aaagcagcag gaatttatcg gaaacgaccg aaaccgaacg gactggattc
      241 ccgcttttgc gggaatgacg gcgacagggt tgctgttata gcggattaac aaaaaccagt
      301 acggcgttgc ctcgccttag ctcaaagaga acgattctct aaggtgctga agtaccgagt
      361 gaatcggttc cgtactattt gtacggtctg cggcttcgcc gccttgtcct gatttttgtt
      421 aatccgctat aaagaccgtc gggcatctgc agccgtcatt cccgcgcagg cgggaatcta
      481 ggtctgttcg gtttcagtta tttccgataa atgcctgttg cttttcattt ctagattccc
      541 actttcgtgg gaatgacggt tcagttgcta cggttactgt caggtttcgg ttatgttgga
      601 atttcgggaa acttatgaat cgtcatttcc gcgcaggcgg gaatctagac tttagaacaa
      661 cagcaatatt cacagattat ctgaaagtc
//
LOCUS       DAXISH010000141          671 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.141, whole genome shotgun sequence.
ACCESSION   DAXISH010000141 DAXISH010000000
VERSION     DAXISH010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.141"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..81)
                     /locus_tag="ACFOV4_002080"
     CDS             complement(<1..81)
                     /locus_tag="ACFOV4_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC7620009.1"
                     /translation="MLPSKYEDNALQIKEKSTERTAPFFCT"
     gene            complement(185..>671)
                     /locus_tag="ACFOV4_002081"
     CDS             complement(185..>671)
                     /locus_tag="ACFOV4_002081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7620010.1"
                     /translation="IGGSLQPHQMPSEHVFGRRFVGGYRSGTSEKGFQAVFGRVVTVE
                     NVIRLPEKFGRFSGSLWYWAQQTQVQIRRCAVIVRMPIQPKQTSVFRKWMFDGAKVVR
                     RMEGNLWVFGMVALEKTCFKGQMPSENRFQTAFSVYLKQTGKGSNILQSSYSHKRFIV
                     N"
BASE COUNT          178 a          178 c          112 g          203 t
ORIGIN      
        1 agtacaaaaa aacggagcag ttctttctgt acttttttct ttaatttgca gtgcgttatc
       61 ttcatatttc gagggtaaca tatctgctaa tctagtacag cccctagttt aaagctttgt
      121 ttcttaagtc cgcagagtat gccatggtta gaccttcaaa gttgagtatt gtactatttt
      181 gtttttaatt aactataaaa cgcttgtgtg aataggaaga ctgcagaata ttgctgcctt
      241 ttcctgtttg ctttaaataa acagaaaatg ccgtctgaaa ccgattttca gacggcattt
      301 gtcccttaaa acacgttttt tcaagcgcga ccataccaaa cacccacagg ttgccttcca
      361 tccttcgtac aacctttgct ccatcaaaca tccacttcct aaatactgat gtctgcttag
      421 gttgaatcgg cattcgtacg attacggcac accgcctaat ctgtacctgc gtctgttgcg
      481 cccaatacca aaggctacct gaaaatctcc caaacttttc aggtagcctt atcacgtttt
      541 cgactgtcac cacacgccca aagaccgcct gaaacccttt ttcagacgtt ccactccgat
      601 accccccaac aaaacgccgc ccgaacacat gttcagacgg catttgatgc ggctgcagac
      661 ttccccctat t
//
LOCUS       DAXISH010000142          661 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.142, whole genome shotgun sequence.
ACCESSION   DAXISH010000142 DAXISH010000000
VERSION     DAXISH010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.142"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            316..661
                     /locus_tag="ACFOV4_002082"
                     /pseudo
     CDS             316..661
                     /locus_tag="ACFOV4_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          189 a          164 c          150 g          158 t
ORIGIN      
        1 gggaatctag tctgttcggt ttcagttatt tccgataaat tcctgctgct ttttatttct
       61 agattcccac tttcgtggga atgacgaaaa gtggcgggaa tgacggttcg ggcattcctt
      121 aaatcacccg tgtatcgctg taaatcttag agatggcgga atatagcgga ttaacaaaaa
      181 ccagtacggc gttgtctcgc cttagctcaa agagaacgat tctctaaggt gctgaagcac
      241 caagtgaatc ggttccgtac tattcgtact gtctgcggct tcgtcgcctt gtcctgattt
      301 ttgttaatcc actatacttt atgccgctac cgcaactggc tggcgcaaga caataccctg
      361 tctgaactgt tggaactgat taaccgccaa ctgaccgaaa aaggtttaaa aatagagaaa
      421 gcatccgccg ccgtcattga cgccaccatt attcagaccg ccggcagcaa acagcgtcag
      481 gccatagaag ttgacgaaga aggacaaatc agcggccaaa ccacaccgag taaggacagc
      541 gatgcccgtt ggataaagaa aaacggcctc tacaaactcg gttacaaaca acatacccgt
      601 accgatgagg aaggctatat cgagaaactg cacattactc ccgccaatgc ccatgagtgc
      661 a
//
LOCUS       DAXISH010000143          654 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.143, whole genome shotgun sequence.
ACCESSION   DAXISH010000143 DAXISH010000000
VERSION     DAXISH010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..654
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.143"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(147..446)
                     /locus_tag="ACFOV4_002083"
                     /pseudo
     CDS             complement(147..446)
                     /locus_tag="ACFOV4_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009349130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
BASE COUNT          125 a          150 c          181 g          198 t
ORIGIN      
        1 attttggttt tctgtccttg tgggaatgat gaaattttaa gttttaagaa tttatcggaa
       61 aaaacagaaa ccgctccgcc gtcattcccg cgcaggcggg aatctagcct cgtcggtgcg
      121 gaaacttatc gggtaaaaag gtttctctag tttggtgtcg attttcttgt cggtgctgtt
      181 gacggcaggt gcttggtgtc gatttcgttg ccggtgactt tgttaacggc gtcggcgctg
      241 gcgttggggg cgtcgcgcgt aaccggctgt ccgcagaacc attttaccga accgttttga
      301 cgcttggccc acagggagag ttttttgcct tggatttctt tgtttacgcc gcttgatttc
      361 atttcggcgg taacgacgcc gtttttgact tcaactttct caacatattt gcctttgatg
      421 tcggaggcgg atgccacgcc ggcggcatca ttaaatcccg tcattcccac gaaagtggga
      481 atctagaact cagggccgga gaaacctttt tacccgataa gtttccgcac cgacaaacct
      541 agattcccgc ctgcgcggga atgacgaagt ttttcggcca tgtgccgtga ttcgggcaat
      601 actcggtgac ggctgatttt ttggaagtgt ttgaagtcgg cgcgtggtgt ttct
//
LOCUS       DAXISH010000144          610 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.144, whole genome shotgun sequence.
ACCESSION   DAXISH010000144 DAXISH010000000
VERSION     DAXISH010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.144"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT          145 a          118 c          163 g          184 t
ORIGIN      
        1 ttttttgggg gctggattca ttttcgactc cgtattcggt tttaactgat taaaaagaaa
       61 gattttcaat gatgttgcag gagcggacta tatcaggttt ggggcgatgt ttcaacacaa
      121 tatagcggat gaacaaaaaa gagaacgatt ctctaaggtg ctgaagcacc aagtgaatcg
      181 gttccgtact atctgtactg tctgcagctc gtcgccttgt cctgattttt gttaatccac
      241 tataaagacc gtcgggcatc tgcagccgtc attcccgcgc aggcgggaat gacgggattt
      301 taggtttctg tttttggttt tctgtccttg tgggaatgat gggatgtagg ttcgtgggaa
      361 tgacgtggtg caggtttccg tgcggatgga ttcgtcattc ccgcgcaggc gggaatccag
      421 accttagaac aacagcaata ttcaaagatt atctgaaagt ccgagattct agattcccac
      481 tttcgtggga atgacggttc agttgctacg gttactgtca ggtttcggtt atgttggaat
      541 ttcgggaaac ttatgaatcg tcatttccgc gcaggcggga atctagacct taaggcagcg
      601 gcaatattca
//
LOCUS       DAXISH010000145          605 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.145, whole genome shotgun sequence.
ACCESSION   DAXISH010000145 DAXISH010000000
VERSION     DAXISH010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.145"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            33..395
                     /locus_tag="ACFOV4_002084"
     CDS             33..395
                     /locus_tag="ACFOV4_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFC7620011.1"
                     /translation="MNQLDQLGTRINLICNVFDKWIGQQDLNYNLFAVLYTLATEGSR
                     TQKHIGEKWSLPKQTVSGVCKTLAGQGLIEWQESEQDRRERLLSLTEKGKAHAAPLTE
                     SAQEFSDKETFAKFPKIP"
     gene            426..>605
                     /locus_tag="ACFOV4_002085"
     CDS             426..>605
                     /locus_tag="ACFOV4_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC7620012.1"
                     /translation="MSTFFRQTAQAMIAKHINRFPLLKLDQVIDWQPIEQYLNRQRTR
                     YLRDHRGRPAYPLLSM"
BASE COUNT          177 a          177 c          132 g          119 t
ORIGIN      
        1 ccgcacaaat ttagtcaata tcaagaccaa ttatgaacca actcgaccaa cttggcaccc
       61 gtatcaacct gatttgcaat gtcttcgaca aatggatcgg gcagcaggat ctgaattaca
      121 acctctttgc cgtactttat accctggcaa ccgaaggcag ccgcacgcaa aagcatatcg
      181 gcgaaaagtg gagcctgccc aaacagaccg tttcaggcgt atgcaaaacc cttgccggac
      241 aagggttgat tgaatggcag gaaagcgaac aggaccggcg cgaacggttg ctgtcgctga
      301 ccgaaaaagg caaagcccat gccgcacctt taacagaaag cgcgcaggaa ttcagcgaca
      361 aagagacctt tgcaaaattc cccaaaatcc cctaaattcc caccaagaca tttaggggat
      421 tttccatgag caccttcttc cggcaaaccg cccaagccat gattgccaaa cacatcaacc
      481 gcttcccgct attgaagttg gaccaggtga ttgattggca gccgatcgaa cagtatctga
      541 atcgtcaaag aacccgttac cttagagacc accgcggccg tcccgcctat cccctgctgt
      601 ccatg
//
LOCUS       DAXISH010000146          604 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.146, whole genome shotgun sequence.
ACCESSION   DAXISH010000146 DAXISH010000000
VERSION     DAXISH010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.146"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..403
                     /locus_tag="ACFOV4_002086"
     CDS             <1..403
                     /locus_tag="ACFOV4_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pilin"
                     /protein_id="HFC7620013.1"
                     /translation="KTPEYYLNHGEWPANNSSAGVATSANIKGKYVQSVEVKNGVVTA
                     TMLSTGVNKEIQGKKLSLWAKRQAGSVKWFCGQPVTRAANAKADKAANADDVAADGTN
                     KIDTKHLPSTCRDASSAVCIETPPTAFYKNT"
BASE COUNT          183 a          192 c          122 g          107 t
ORIGIN      
        1 aaaaacaccc gagtattacc tgaatcacgg cgaatggccc gccaacaaca gttctgccgg
       61 cgtggcaacc tccgccaaca tcaaaggcaa atatgttcaa agcgttgaag tcaaaaacgg
      121 cgtcgttacc gccacaatgc tttcaaccgg cgtaaacaaa gaaatccaag gcaaaaaact
      181 ctccctgtgg gccaagcgtc aagccggttc ggtaaaatgg ttctgcggac agccggttac
      241 gcgcgccgcc aacgccaaag ccgacaaagc cgccaacgcc gacgacgtcg ccgccgacgg
      301 caccaacaaa atcgacacca agcacctgcc gtcaacctgc cgcgacgctt catctgccgt
      361 ttgcatagaa acaccaccta cggctttcta taaaaatacc taaaccgtca ttcccacgaa
      421 cctacatccc gtcattccca cgaaagtggg aatccagaac gcaaaatcta aagaaaccgc
      481 tttcccgata agtttccgta ccgacagacc tagattcccg cctgcgcggg aatgacggcg
      541 gagcggtttc tgttgctccc gataaattcc taaaacttaa aatttcatca ttcccacaaa
      601 aaca
//
LOCUS       DAXISH010000147          601 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.147, whole genome shotgun sequence.
ACCESSION   DAXISH010000147 DAXISH010000000
VERSION     DAXISH010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.147"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(354..>601)
                     /locus_tag="ACFOV4_002087"
     CDS             complement(354..>601)
                     /locus_tag="ACFOV4_002087"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7620014.1"
                     /translation="SAPTDLDSRLRGNDGGAVSVFSGKYPQAKILLFSQKQKTKNSNL
                     KFVIPAQAGIQCVEFQLFRINFETLIASFPRKWEFRT"
BASE COUNT          146 a          116 c          156 g          183 t
ORIGIN      
        1 tttttaaaat ttttatattc acatagatgg ggatgatggg atttagggtt ctgattttgt
       61 ttttgagaga atgaaggaat ttgagattgt gggtgattat cgggaaaaat agaatctttc
      121 cgccgtcatt cccacgcagg cgggaatcta ggtctgtcgg tgcggaaact tatcgggcaa
      181 aacggtttct tgagattttg cgtcctggat tcccactttc gtgggaatga cggcagagcg
      241 gattctgttg ctcccgataa atgccgcaat ctcaaatccc gtcattcccg cgcaggcggg
      301 aatctaggtc tgtcggcaca gaaacttatc gggtaaaacg gtttcttgag attttacgtt
      361 ctgaattccc actttcgtgg gaatgacgcg attagagttt caaaatttat tctaaatagc
      421 tgaaactcaa cgcactggat tcccgcctgc gcgggaatga cgaatttcag gttgctgttt
      481 ttggttttct gtttttgtga aaataacagg attttagctt gtgggtattt accggaaaaa
      541 acagaaaccg ctccgccgtc attcccgcgc aggcgggaat ctaggtctgt cggtgcggaa
      601 a
//
LOCUS       DAXISH010000148          583 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.148, whole genome shotgun sequence.
ACCESSION   DAXISH010000148 DAXISH010000000
VERSION     DAXISH010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.148"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(152..>583)
                     /locus_tag="ACFOV4_002088"
     CDS             complement(152..>583)
                     /locus_tag="ACFOV4_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HFC7620015.1"
                     /translation="IGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYHVDKNSDTMHFK
                     GFKAADVHFIRSGSDLVLSASEQDNVRISGFFYGENHRVDTFVFDDAAISNPDFAKYI
                     NAGNNLVQSMSVFGSNTAATGGNVDANIQSVQQPLLVTPSA"
BASE COUNT          183 a          129 c          107 g          164 t
ORIGIN      
        1 gtactggttt ttgtgaatcc actatattgc tagaagtgca ccgattaagg ttaattaaaa
       61 tacgaccctt atcccaatat taagaaaaac agcaatcaaa ataaacttga ttgctgtttt
      121 tcagtttaag ccatgaatgt gattaggctc cttatgcaga tggcgttacc aataacggct
      181 gctgtacgga ttgtatattg gcatccacat ttcctcctgt cgcagcagta ttagaaccga
      241 acacagacat agactgtacc aaattattgc cagcattaat atacttggca aaatctggat
      301 tactgatagc tgcatcatca aagacaaatg tatctacacg atggttttca ccatagaaga
      361 atccggaaat acgtacgttg tcttgttcag aagcgctaag caccaaatca cttccggaac
      421 ggataaaatg aacatctgct gctttaaatc ctttaaagtg catagtgtca gagtttttat
      481 ccacatggta attatagacc gtatcctgac cgaagccttt gccgaagaca taagtatccg
      541 aaccgctgcc gccctccaag taatcattac cggcaccgcc gat
//
LOCUS       DAXISH010000149          583 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.149, whole genome shotgun sequence.
ACCESSION   DAXISH010000149 DAXISH010000000
VERSION     DAXISH010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.149"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT          145 a          120 c          151 g          167 t
ORIGIN      
        1 tgggttcgtg ggaatgacgt ggtgcaggtt tccgtgcgga tggattcgtc attcccgcgc
       61 aggcgggaat ccagacctta gaacaacagc aatattcaaa gattatctga aagtctgaga
      121 ttctagattc ccacttttgc gggaatgacg gttcagttgc tacggttact gtcaggtttc
      181 ggttatgttg gaatttcggg aaacttatga atcgtcattc ccgcgcaggc gggaatctag
      241 aatttcaatg tctcaagaat ttatcggaaa aaaccaaaac ccttccgccg tcattcccac
      301 gaaagtggga atctagaaat gaaaagcagc aggcatttat cggaaatgac cgaaactgaa
      361 cggactggat tcccgctttt gcgggaatga cggttcagtt gctacggtta ctgtcaggtt
      421 tcggttcagt tgctacggtt actgtcaggt ttcggttatg ttggaatttc gggaaactta
      481 tgaatcgtca ttcccgcgca ggcgggaatc tagaccgttc ggtacggaaa cttatcgggt
      541 aaaacggttt cttcagattt tacgttctag attcccactt ttg
//
LOCUS       DAXISH010000150          542 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.150, whole genome shotgun sequence.
ACCESSION   DAXISH010000150 DAXISH010000000
VERSION     DAXISH010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.150"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(<1..173)
                     /locus_tag="ACFOV4_002089"
     CDS             complement(<1..173)
                     /locus_tag="ACFOV4_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC7620016.1"
                     /translation="MKYRRFYRNGGTYFFTVVTNKRQKILTDDAVRLALRQAVMAVRE
                     RYPFEILAWVLMP"
BASE COUNT          143 a          143 c          123 g          133 t
ORIGIN      
        1 tcgggcatca acacccatgc caaaatttca aacggatacc gttcgcgcac cgccattacc
       61 gcctgccgta aagccaaacg caccgcatca tcggtcaaaa tcttctgccg tttattggtt
      121 acaaccgtaa aaaagtaagt gccgccattg cggtaaaaac gacggtattt catagtatta
      181 tgctcggaat gattttgtag gtcggattct tgaattcgac attttgggca ttgctgcaat
      241 ggattgcaat gatgggaatg ttaaaggttt tgtcggatac aagtatccga cctacgcttg
      301 ctgaaccgtc attcccacgg aagtgggaat ctggaatctc ggggtttcag tcatttccga
      361 tagattcccg ccgcgtcagg gggctggatt cccgcctgcg cgggaatgac gaatccatcc
      421 gcacggaaac ctgcaccacg tcattcctac gaacctacat cccgtcattc ccacgaaagt
      481 ggcaatccag aacgtaaaat ctgaagaaac cgttttatcc gatacgtttc cgcaccgaca
      541 ga
//
LOCUS       DAXISH010000151          542 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.151, whole genome shotgun sequence.
ACCESSION   DAXISH010000151 DAXISH010000000
VERSION     DAXISH010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.151"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT          136 a          105 c          125 g          176 t
ORIGIN      
        1 tgttcctgtg caaacggcag ttgaatcatc gcggcaggtt tccgtgcgga tggcttcgtc
       61 attcccgcgc aggcgggaat ccagcctcgt cggcacggaa acttatcggg aaaacggttt
      121 ctttagattt tacgttctgg attcccactt tcgcgggaat gacgaatttt aggtttctgt
      181 ttttggtttt ctgtccttgt gggaatgatg aaattttaag ttttaggaat ttatcggaaa
      241 aaacagaaac cgctctgccg tcattcccac gaaagtggga atccagcctt gtcggtacgg
      301 aaacttatcg ggtaaaacgg tttcttgaga ttttacgttc tggattccca ctttcgtggg
      361 aatgacggga ttaaagtttc aaaatttatc taaataactg aaactcaacg aactagattc
      421 ccgcttttgc gggaatgacg ggatttaagt ttcaaaattt attctaaata actgaaactc
      481 aacgaactag attcccactt tcgtgggaat gacgaatttt aggtttctgt ttttggtttt
      541 ct
//
LOCUS       DAXISH010000152          508 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.152, whole genome shotgun sequence.
ACCESSION   DAXISH010000152 DAXISH010000000
VERSION     DAXISH010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.152"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            153..508
                     /locus_tag="ACFOV4_002090"
                     /pseudo
     CDS             153..508
                     /locus_tag="ACFOV4_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          135 a          129 c          126 g          118 t
ORIGIN      
        1 aaatttttat agtggattaa caaaaaccag tacggcggtg cctcgcctta gctcaaagag
       61 aacgattctc taaggtgctg aagcaccaag tgaatgggtt ccgtactatt tgtactgtct
      121 gcggcttcgt cgccttgtcc tgatttttgt taatccacta tacctccgcc aatgcccatg
      181 agtgcaaaca cctgtcgccg ttgttggaag gactgcccaa aggtacgacc gtctatgccg
      241 acaaaggcta tgacagtgcg gaaaaccggc aacatctgga agaacatcag ttgcaggacg
      301 gcattatgcg caaagcctgc cgcaaccgtc cgctgacgga agcgcaaacc aaacgcaacc
      361 gatatttgtc gaagacccgt tatgtggtcg aacaaagctt cggtacgctg caccgcaaat
      421 tccgctatgc tcgggcagcc tatttcggac tgattaaagt gagtgcgcaa agccatctga
      481 aggcgatgtg tttgaacctg ttgaaagc
//
LOCUS       DAXISH010000153          486 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.153, whole genome shotgun sequence.
ACCESSION   DAXISH010000153 DAXISH010000000
VERSION     DAXISH010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.153"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(159..470)
                     /gene="rpsJ"
                     /locus_tag="ACFOV4_002091"
     CDS             complement(159..470)
                     /gene="rpsJ"
                     /locus_tag="ACFOV4_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012504051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFC7620017.1"
                     /translation="MANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPT
                     KIERFNILRSPHVNKTSREQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKV
                     Q"
BASE COUNT          121 a           97 c          122 g          146 t
ORIGIN      
        1 atcatggctt gggcggtttg ctgaaagaag gtgctcatga gaaatctcct aaatgtcttg
       61 gtgggaattt aggggatttt ggggaatttt gcaaaggtct cggcataaca taaaaaatcc
      121 ccaagcattg attgcttggg gattttcaat agtccgaatt attggacttt gatttctaca
      181 tcaacaccgg ccggcaaatc cagcttcatc agcgcatcgg tagttttatc ggtccaatcc
      241 acgatgtcca tcaggcgcaa gtgggtgcgg atttccaatt gttcacggga agttttgttc
      301 acgtgcggag aacgcagaat gttgaaacgt tcgattttgg tcggcaacgg aatcggacct
      361 tttacaacgg caccggtacg ttttgcagtt tcaacgattt cttgtgcaga acggtcaatc
      421 agggcgtaat cataagcttt caggcggata cggatttttt ggtttgccat ttatcaatat
      481 ccttca
//
LOCUS       DAXISH010000154          485 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.154, whole genome shotgun sequence.
ACCESSION   DAXISH010000154 DAXISH010000000
VERSION     DAXISH010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.154"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT          112 a          108 c          125 g          140 t
ORIGIN      
        1 caaaaccctt ccgccgtcat tcccacgaaa gtgggaatct agaaatgaaa agcagcaggc
       61 atttatcgga aatgaccgaa actgaacgga ctggattccc gcttttgcgg gaatgacggc
      121 gacagggttg ctgttatagt ggatgaacaa aaaccagtac ggcgttgcct cgccttagct
      181 caaagagaac gattctctaa ggtgctgaag caccgagtga atcggttccg tactatctgt
      241 actgtctgca gctcgtcgcc ttgtcctgat ttttgttaat ccactataaa gaccgtcggg
      301 catctgcagc cgtcattccc gcgcaggcgg gaatctagtc tgttcggttt cagttatttc
      361 cgataaatgc ctgttgcttt tcatttctag attcccactt tcgtgggaat gacgggattt
      421 taggtttctg attttggttt tctgtccttg tgggaatgac gggatgtagg ttcgtaggaa
      481 tgacg
//
LOCUS       DAXISH010000155          440 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.155, whole genome shotgun sequence.
ACCESSION   DAXISH010000155 DAXISH010000000
VERSION     DAXISH010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.155"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT          120 a           91 c          103 g          126 t
ORIGIN      
        1 ttcccacttt cgtgggaatg acggcggagc ggtttctgct ttttccaata aatgccccca
       61 acctaaaatc cgtcattccc gcgtaggcgg gaatctagac attcaatgct aaggcaattt
      121 atcggaaatg actgaaactc aaaaaactgg attcccactt tcgtgggaat gacgggatgc
      181 aggtttccgt atggatggat tcgtcattcc cgcgcaggcg ggaatctagg tctgtcagtg
      241 cggaaactta tcaggtaaaa cggtttcttg agattttgcg tcctggattc ccactttcgt
      301 gggaatgacg cgattagagt ttcaaaattt attctaaata gctgaaactc aatgaaccgg
      361 attcccgcct gagcgggaat gacgggatta agttttcaaa attcatcaga aattattgat
      421 tcaatggcat aaatttttga
//
LOCUS       DAXISH010000156          421 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.156, whole genome shotgun sequence.
ACCESSION   DAXISH010000156 DAXISH010000000
VERSION     DAXISH010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.156"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..410
                     /locus_tag="ACFOV4_002092"
     CDS             <1..410
                     /locus_tag="ACFOV4_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pilin"
                     /protein_id="HFC7620018.1"
                     /translation="KYVKEVTVANGVVTATMLSSGVNKEIQGKKLSLWAKRQNGSVKW
                     FCGQPVTRDKADKADDGVTAANDKQIDTKHLPSTCRDDSSTGCIETPRADFKHFQKIS
                     RYRVLPESRHMAEKLRHSRAGGNPGLSVRKLIG"
BASE COUNT          125 a          121 c          100 g           75 t
ORIGIN      
        1 gaaaatatgt taaggaagtt acagtcgcaa acggcgtcgt taccgccaca atgctttcaa
       61 gcggcgtaaa caaagaaatc caaggcaaaa aactctccct gtgggccaag cgtcaaaacg
      121 gttcggtaaa atggttctgc ggacagccgg ttacgcgcga caaagccgac aaagccgacg
      181 acggcgttac cgccgccaac gacaagcaga tcgacaccaa gcacctgccg tcaacctgcc
      241 gcgatgattc atctaccggt tgcatagaaa caccacgcgc cgacttcaaa cacttccaaa
      301 aaatcagccg ttaccgagta ttgcccgaat cacggcacat ggccgaaaaa cttcgtcatt
      361 cccgcgcagg cgggaatcca ggtctgtcgg tacggaaact tatcgggtaa aacggtttct
      421 t
//
LOCUS       DAXISH010000157          410 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.157, whole genome shotgun sequence.
ACCESSION   DAXISH010000157 DAXISH010000000
VERSION     DAXISH010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.157"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            1..121
                     /locus_tag="ACFOV4_002093"
                     /pseudo
     CDS             1..121
                     /locus_tag="ACFOV4_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581605.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
     gene            complement(258..>410)
                     /locus_tag="ACFOV4_002094"
     CDS             complement(258..>410)
                     /locus_tag="ACFOV4_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC7620019.1"
                     /translation="EQSFGTLHRKFRYARAAYFGLIKVSAQSHLKAMCLNLLKAANRL
                     SASAAA"
BASE COUNT           99 a          122 c           91 g           98 t
ORIGIN      
        1 agccattctt ttggctgaag gtcaaaaatc agccgtcacc gagtattacc tgaatcacgg
       61 caaatggccc ggcggcaaca gtgatgccga cgtggcatcc tcctctaaaa tcaaaggaaa
      121 gagacctttg caaaattcct ttccctcccg acagccgaaa cccaaacaca ggttttcggc
      181 tgttttcagc tgttttcgcc ccaaataccc ccttaatcct gcccggatac ccgataatca
      241 ggcatccggg ctgcttttta ggcggcagcg gacgcactta acctgttggc cgctttcaac
      301 aggttcaaac acatcgcctt cagatggctt tgcgcactca ctttaatcag tccgaaatag
      361 gctgcccgcg catagcggaa tttgcggtgc agcgtaccga agctttgttc
//
LOCUS       DAXISH010000158          410 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.158, whole genome shotgun sequence.
ACCESSION   DAXISH010000158 DAXISH010000000
VERSION     DAXISH010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.158"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT          105 a          123 c           97 g           85 t
ORIGIN      
        1 cgtgggaatg acggttcagt tgcgttccga caacaccgca atcttgaaac ccgtccgaca
       61 acaccgtaat cttaagaccc gtcattcccg cacaggcggg aatctagacc tgtccgcaca
      121 gaaacttatc ggataaaaac agttgcccaa accccgcgtt ctagattccc actttcgtgg
      181 gaatgacgtg gtgcaggttc cgtatggatg gattcgtcat tcccgcacag gcgggaatcc
      241 agacctccga cgcggcggga atctatcgga aatgactgaa accccgagat tctagattcc
      301 cacttccgtg ggaatgacgg ttcagttgcg ctccgacaac accgcaatct tgaaacccgt
      361 ccgacaacac cgtaatctta aaacccgtca ttcccgcgca ggtgggaatc
//
LOCUS       DAXISH010000159          356 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.159, whole genome shotgun sequence.
ACCESSION   DAXISH010000159 DAXISH010000000
VERSION     DAXISH010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.159"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            26..>356
                     /locus_tag="ACFOV4_002095"
     CDS             26..>356
                     /locus_tag="ACFOV4_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595-like element ISNme3 family transposase"
                     /protein_id="HFC7620020.1"
                     /translation="MKLKNKYQKFSKISEQKFREIIRCFALDLTASDTAKMTGISVRG
                     INPIFLKIRHRIAALCEQSSPLSGVVELDESYFGARRIRGKRGRGASGKTIVFGILKR
                     NGVVYTEI"
BASE COUNT          110 a           74 c           80 g           92 t
ORIGIN      
        1 tcaaaaaacc tgataagctc ctaatatgaa actaaaaaat aagtatcaaa agttcagcaa
       61 aatttcagag caaaagttta gagaaataat ccgctgtttc gctcttgatt tgaccgcttc
      121 cgatactgct aaaatgaccg gcattagtgt acgcggtatc aatcctattt tcctgaaaat
      181 cagacacagg attgctgctc tgtgcgaaca aagctcacca ctgtccggtg tggtcgaatt
      241 agatgaatct tactttggtg cgcgacgtat caggggtaag cgcggtcgcg gagcgtcagg
      301 taaaaccatc gtatttggca tactgaaacg caatggcgtg gtctatacgg aaatcg
//
LOCUS       DAXISH010000160          334 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.160, whole genome shotgun sequence.
ACCESSION   DAXISH010000160 DAXISH010000000
VERSION     DAXISH010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.160"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT          101 a           74 c           85 g           74 t
ORIGIN      
        1 agggttaagg gggtatttgg gtaaaattag gaggtatttg gggcgaaaat agacgaaaac
       61 ctgtgtttgg gtttcggctg tcgggaggga aaggaatttt gcaaagatct catcctgtta
      121 ttttcacaaa aacagaaaac caaaaacagc aacctgaaat tcgtcattcc cgcgcaggcg
      181 ggaatccaga cccccaacgc ggcaggaatc tatcggaaat aaccgaaacc ggacgaacct
      241 agattcccgc tttcgcggga atgacggcag agtggtttca gttgctcccg ataaatgccg
      301 ccatctcaag tctcgtcatt cccttaaaac agaa
//
LOCUS       DAXISH010000161          327 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.161, whole genome shotgun sequence.
ACCESSION   DAXISH010000161 DAXISH010000000
VERSION     DAXISH010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.161"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
BASE COUNT           87 a           64 c           87 g           89 t
ORIGIN      
        1 tttttgacac attttcatga tttcaaatcc cgttattccc aagtggacgg aaacccgata
       61 atgggaagcc gcagagactt atcgggaaaa cggcaagccc tccgccgtca ttcccgcgca
      121 ggcgggaatc tagaaataaa aaaccacggt gttatcggca atgactgaaa ccggagaaat
      181 gacgaaattg aagcgtgcgg aaatgtgtcg gaaatcgctg aagccggata aactagattc
      241 ccgcttttgc gggaatgacg ggattttagg tttttggttt gttttcgcgg caatgatggg
      301 attttaggtt tttggtttgt tttcacg
//
LOCUS       DAXISH010000162          304 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.162, whole genome shotgun sequence.
ACCESSION   DAXISH010000162 DAXISH010000000
VERSION     DAXISH010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.162"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            complement(1..>304)
                     /locus_tag="ACFOV4_002096"
     CDS             complement(1..>304)
                     /locus_tag="ACFOV4_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS1595-like element ISNme3 family transposase"
                     /protein_id="HFC7620021.1"
                     /translation="HISADSEINTDGWKAYDGLVDMGYEKHYRVHHGSNEFARGKQHI
                     NGIESFWSYTKGRLAKFHGISKEMFYLHLKETEFRFNHRHEDLGKILMKMLRNNPI"
BASE COUNT           92 a           67 c           49 g           96 t
ORIGIN      
        1 ttaaattggg ttatttcgaa gcatcttcat taatatttta cctaaatctt catgccggtg
       61 gttaaaccta aactccgttt ctttgagatg cagataaaac atctctttgg aaataccatg
      121 aaatttagcc aaacgcccct tagtataact ccaaaaagat tcaataccat tgatatgttg
      181 ctttcctcga gcaaactcat tggaaccatg atggacacgg taatgcttct catagcccat
      241 atcgacaaga ccgtcatatg ctttccagcc gtcagtattg atttcactgt cagcagatat
      301 gtga
//
LOCUS       DAXISH010000163          301 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.163, whole genome shotgun sequence.
ACCESSION   DAXISH010000163 DAXISH010000000
VERSION     DAXISH010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.163"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            82..>301
                     /locus_tag="ACFOV4_002097"
     CDS             82..>301
                     /locus_tag="ACFOV4_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFC7620022.1"
                     /translation="MLRLTALAVCTVLALGACSPQNSDSAPQAKEQAVSAAQSESASL
                     TVKTARGDVQIPQNPERIAVYDLGMLDTL"
BASE COUNT           66 a           94 c           65 g           76 t
ORIGIN      
        1 attatcattt atcctttcta aagccgttcc ggtttgtccg accggcggct ttgccccaat
       61 atccccattt tggagacacc tatgttacgt ttgactgctt tagccgtatg caccgtcctc
      121 gccttgggcg cgtgttcgcc gcaaaattcc gactctgccc cacaagccaa agaacaggca
      181 gtttccgccg cacaatccga aagcgcgtcc ctgactgtca aaacggcgcg cggcgatgtt
      241 caaataccgc aaaaccccga acgtatcgcc gtttacgatt tgggtatgct cgacacttta
      301 a
//
LOCUS       DAXISH010000164          296 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.164, whole genome shotgun sequence.
ACCESSION   DAXISH010000164 DAXISH010000000
VERSION     DAXISH010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.164"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..>296
                     /locus_tag="ACFOV4_002098"
     CDS             <1..>296
                     /locus_tag="ACFOV4_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
                     /protein_id="HFC7620023.1"
                     /translation="VVTSGAGTGAVLGLNGAAAAATDAAFASLASQASVSFINNKGDV
                     GKTLKELGRSSTVKNLVVAAATAGVADKIGASALNNVSDKQWINNLTVNLANAG"
BASE COUNT           76 a           86 c           86 g           48 t
ORIGIN      
        1 gtggtcacct caggcgcagg aaccggagcc gtattgggat taaacggtgc ggccgccgcc
       61 gcaaccgatg cagcattcgc ctctttggcc agccaggctt ccgtatcgtt catcaacaac
      121 aaaggcgatg tcggcaaaac cctgaaagag ctgggcagaa gcagcacggt gaaaaatctg
      181 gtggttgccg ccgctaccgc aggcgtagcc gacaaaatcg gcgcttcggc actgaacaat
      241 gtcagcgata agcagtggat caacaacctg accgtcaacc tagccaatgc gggcag
//
LOCUS       DAXISH010000165          290 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.165, whole genome shotgun sequence.
ACCESSION   DAXISH010000165 DAXISH010000000
VERSION     DAXISH010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.165"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..222
                     /locus_tag="ACFOV4_002099"
     CDS             <1..222
                     /locus_tag="ACFOV4_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009347026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC7620024.1"
                     /translation="GFRLSGGKGILQRSRALIAAKIDQAEISDSEKSWLKKELGKIKD
                     TALSTLTENAINAIPAATLITLLKKFVGL"
     gene            complement(219..>290)
                     /locus_tag="ACFOV4_002100"
     CDS             complement(219..>290)
                     /locus_tag="ACFOV4_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFC7620025.1"
                     /translation="PKHLPAFVEVLEPFGAEVEKKFG"
BASE COUNT           91 a           65 c           63 g           71 t
ORIGIN      
        1 gggtttcggc tgtcgggagg gaaaggaatt ttgcaaaggt ctcgggcttt aattgcggca
       61 aaaatagacc aagcggagat ttctgattca gaaaaaagct ggttgaaaaa agaattaggg
      121 aaaatcaagg acactgcatt aagtacgctt acggaaaatg caattaatgc tatccctgcc
      181 gccaccctca ttactctttt aaaaaaattt gttggcctct aaccaaactt cttctccact
      241 tccgccccaa acggctccaa tacctccaca aaggcaggca aatgtttggg
//
LOCUS       DAXISH010000166          284 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate S22BD04179
            SAMN42001076-rid22908003.denovo.166, whole genome shotgun sequence.
ACCESSION   DAXISH010000166 DAXISH010000000
VERSION     DAXISH010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42001076
            Sequence Read Archive: SRR29505777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002328202.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002328202.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 01:42:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,046
            Genes (coding)                    :: 1,917
            CDSs (with protein)               :: 1,917
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 54 of 129
            Pseudo Genes (incomplete)         :: 84 of 129
            Pseudo Genes (internal stop)      :: 13 of 129
            Pseudo Genes (multiple problems)  :: 20 of 129
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42001076-rid22908003.denovo.166"
                     /isolate="S22BD04179"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Belgium"
                     /collection_date="2022-05-28"
                     /collected_by="Belgian National Reference Centre for
                     Neisseria meningitidis"
     gene            <1..>284
                     /locus_tag="ACFOV4_002101"
     CDS             <1..>284
                     /locus_tag="ACFOV4_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS1595-like element IS1016C family transposase"
                     /protein_id="HFC7620026.1"
                     /translation="AADEVFEGPVEPDESDFGGRRKGRRGRGAAGKVVVFGILKRNGR
                     VYTVVVDNAKSETLLPVIKKKIMPDSIVYTNSLSSCDKLDVSGFIHYRIN"
BASE COUNT           70 a           63 c           85 g           66 t
ORIGIN      
        1 tggctgccga tgaggttttt gagggccctg tcgagccgga cgaaagcgat ttcggcggac
       61 ggcgtaaagg cagacgtggt cgcggtgcgg caggaaaagt ggttgtcttc ggcattctga
      121 aacgcaacgg acgggtctat accgttgtgg tggataatgc caagtctgaa acgttactcc
      181 ctgtcatcaa aaagaaaatc atgccggaca gcattgttta taccaatagt ctgagcagct
      241 gcgacaagtt ggacgtgagc ggttttatcc attaccgcat caac
//
